ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:1.10.8.60 352 435 1.9E-33 T 09-03-2017 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 715 1.3E-53 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SUPERFAMILY SSF81923 3 144 5.59E-32 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SUPERFAMILY SSF52540 170 443 7.2E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 655 669 4.1E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 593 611 4.1E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 548 566 4.1E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 622 640 4.1E-40 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SMART SM00382 544 694 6.0E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SMART SM00382 207 351 6.8E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SMART SM01086 722 815 8.7E-39 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:3.40.50.300 705 733 6.0E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:3.40.50.300 497 670 6.0E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:1.10.1780.10 1 143 2.0E-52 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 302 314 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 578 596 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:3.40.50.300 170 350 2.2E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF02151 UvrB/uvrC motif 424 456 8.7E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 802 2.9E-26 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 SUPERFAMILY SSF52540 493 806 2.61E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Gene3D G3DSA:1.10.8.60 734 818 4.0E-33 T 09-03-2017 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 212 341 3.1E-13 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.4E-17 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS17850 31a51880b8a08e062bd91d76b9958ab7 830 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.5E-17 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 372 394 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 510 526 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 208 223 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 485 501 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 294 308 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 259 279 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 PRINTS PR00743 Glycosyl hydrolase family 36 signature 322 337 1.1E-43 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 Gene3D G3DSA:3.20.20.70 292 380 1.2E-41 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 Gene3D G3DSA:3.20.20.70 417 587 1.2E-41 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 SUPERFAMILY SSF51445 290 619 4.02E-95 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 22 246 1.3E-40 T 09-03-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 ProSitePatterns PS00512 Alpha-galactosidase signature. 323 339 - T 09-03-2017 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS01745 2c92ea37859e95af295436c9e04f8b94 723 Pfam PF02065 Melibiase 256 600 5.9E-116 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 ARZXY2_RS18960 643b2af90d83c9f1181f43cce6017ca1 77 Gene3D G3DSA:3.30.70.100 6 73 2.9E-19 T 09-03-2017 ARZXY2_RS18960 643b2af90d83c9f1181f43cce6017ca1 77 Pfam PF00403 Heavy-metal-associated domain 9 70 7.0E-14 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS18960 643b2af90d83c9f1181f43cce6017ca1 77 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ARZXY2_RS18960 643b2af90d83c9f1181f43cce6017ca1 77 SUPERFAMILY SSF55008 2 72 1.28E-14 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 SUPERFAMILY SSF54909 58 142 7.24E-16 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 Gene3D G3DSA:3.30.70.920 51 136 4.3E-17 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 SUPERFAMILY SSF46785 1 58 3.47E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 SMART SM00344 2 104 2.0E-19 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 Pfam PF01037 Lrp/AsnC ligand binding domain 64 133 3.4E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 Gene3D G3DSA:1.10.10.10 2 45 7.3E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 44 1.6E-11 T 09-03-2017 ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 44 3.1E-6 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS04040 7a7ac0a19c0c4df8f8c28ee95c821e0a 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 25 3.1E-6 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS10440 39a7423643753d462d6a9f258e5bb260 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 160 6.8E-52 T 09-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC ARZXY2_RS10440 39a7423643753d462d6a9f258e5bb260 165 SUPERFAMILY SSF55826 10 160 8.89E-43 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS10440 39a7423643753d462d6a9f258e5bb260 165 Pfam PF04073 Aminoacyl-tRNA editing domain 40 152 1.7E-25 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS10440 39a7423643753d462d6a9f258e5bb260 165 PIRSF PIRSF006181 5 164 8.3E-49 T 09-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC ARZXY2_RS10440 39a7423643753d462d6a9f258e5bb260 165 Gene3D G3DSA:3.90.960.10 3 160 8.8E-58 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 SUPERFAMILY SSF51735 101 278 3.04E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 Gene3D G3DSA:3.40.50.720 108 280 2.4E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 Gene3D G3DSA:3.40.50.720 5 107 9.1E-8 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 278 1.3E-44 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS09715 e5fceb6686b075fc24aa80c285167cfa 337 SUPERFAMILY SSF52283 7 130 1.34E-7 T 09-03-2017 ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 31 335 8.7E-36 T 09-03-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 Gene3D G3DSA:1.20.272.20 231 327 1.7E-6 T 09-03-2017 ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 Gene3D G3DSA:1.10.8.60 156 230 5.5E-7 T 09-03-2017 ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 Pfam PF06144 DNA polymerase III, delta subunit 35 194 9.2E-9 T 09-03-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 Gene3D G3DSA:3.40.50.300 31 124 3.9E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 SUPERFAMILY SSF52540 28 201 9.03E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08240 aa410e1e9b7d80cce1e9609eec4446d0 344 SUPERFAMILY SSF48019 222 338 2.47E-22 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 SUPERFAMILY SSF52922 230 357 2.75E-36 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 SUPERFAMILY SSF52518 33 212 6.38E-66 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 Gene3D G3DSA:3.40.50.920 234 355 1.7E-41 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 Gene3D G3DSA:3.40.50.970 32 211 3.4E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 SMART SM00861 34 209 2.4E-63 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 Pfam PF02780 Transketolase, C-terminal domain 230 351 8.3E-36 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS02670 cd927ccec103707a83c35074391171c3 362 Pfam PF02779 Transketolase, pyrimidine binding domain 33 207 7.5E-45 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS04415 d20517da464c3cd178226a0e48cdd7b8 220 SUPERFAMILY SSF51391 7 218 1.09E-55 T 09-03-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ARZXY2_RS04415 d20517da464c3cd178226a0e48cdd7b8 220 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 11 214 5.9E-54 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ARZXY2_RS04415 d20517da464c3cd178226a0e48cdd7b8 220 Gene3D G3DSA:3.20.20.70 8 219 2.2E-66 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS04415 d20517da464c3cd178226a0e48cdd7b8 220 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 9 219 23.599 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ARZXY2_RS04415 d20517da464c3cd178226a0e48cdd7b8 220 Pfam PF02581 Thiamine monophosphate synthase/TENI 12 201 5.2E-49 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ARZXY2_RS16250 c10dee13f44f3a294c2dd62704ed2a14 313 SUPERFAMILY SSF161098 91 298 2.75E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16250 c10dee13f44f3a294c2dd62704ed2a14 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 311 6.8E-32 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16250 c10dee13f44f3a294c2dd62704ed2a14 313 Gene3D G3DSA:1.10.3720.10 89 308 3.8E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 SUPERFAMILY SSF81593 341 493 1.96E-36 T 09-03-2017 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 597 835 2.0E-42 T 09-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 75 327 7.8E-43 T 09-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 SUPERFAMILY SSF81301 60 334 2.45E-57 T 09-03-2017 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 SUPERFAMILY SSF81301 569 844 1.57E-58 T 09-03-2017 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 SUPERFAMILY SSF81593 852 1000 1.02E-36 T 09-03-2017 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Pfam PF08335 GlnD PII-uridylyltransferase 347 492 3.0E-34 T 09-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Pfam PF08335 GlnD PII-uridylyltransferase 858 998 7.5E-24 T 09-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Gene3D G3DSA:3.30.460.10 681 844 4.7E-44 T 09-03-2017 ARZXY2_RS10745 bb070e85dc9f5168c77617c5ebece69a 1003 Gene3D G3DSA:3.30.460.10 175 334 6.5E-51 T 09-03-2017 ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 Pfam PF00266 Aminotransferase class-V 144 333 5.0E-15 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 SUPERFAMILY SSF53383 14 372 8.3E-72 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 PIRSF PIRSF000525 4 375 5.9E-71 T 09-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 Gene3D G3DSA:3.40.640.10 22 268 1.3E-46 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 Gene3D G3DSA:3.90.1150.10 269 374 1.2E-6 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS14245 a1ccdada234c5e92c8a226f1b343b2dc 376 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 14 373 3.7E-187 T 09-03-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 PIRSF PIRSF006485 77 515 1.0E-156 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Hamap MF_00195 GTPase Der [der]. 78 510 35.342 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 254 408 1.5E-20 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 80 230 7.0E-24 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 79 507 2.6E-156 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 429 507 2.4E-23 T 09-03-2017 IPR032859 GTPase Der, C-terminal KH-domain-like ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 SMART SM00382 77 241 0.044 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 SMART SM00382 252 395 0.0018 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Gene3D G3DSA:3.30.300.20 435 509 1.1E-26 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Pfam PF01926 50S ribosome-binding GTPase 81 195 1.1E-25 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Pfam PF01926 50S ribosome-binding GTPase 255 373 8.5E-21 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Gene3D G3DSA:3.40.50.300 75 240 4.7E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 SUPERFAMILY SSF52540 213 509 7.3E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 Gene3D G3DSA:3.40.50.300 254 434 5.2E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 256 276 1.4E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 305 320 1.4E-6 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11020 9d2a850fe8254abccc243102d4bb63ea 516 SUPERFAMILY SSF52540 79 242 3.62E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 589 2.5E-251 T 09-03-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Gene3D G3DSA:3.30.559.10 341 580 6.9E-82 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Gene3D G3DSA:2.40.50.100 2 96 4.9E-29 T 09-03-2017 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Gene3D G3DSA:2.40.50.100 134 226 4.6E-29 T 09-03-2017 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 158 187 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Pfam PF00364 Biotin-requiring enzyme 134 207 9.2E-22 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Pfam PF00364 Biotin-requiring enzyme 4 76 6.6E-22 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Pfam PF02817 e3 binding domain 284 317 2.4E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 SUPERFAMILY SSF51230 134 226 1.44E-26 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 SUPERFAMILY SSF52777 341 580 1.29E-78 T 09-03-2017 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Gene3D G3DSA:4.10.320.10 279 329 6.4E-19 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 SUPERFAMILY SSF51230 3 95 8.64E-26 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 SUPERFAMILY SSF47005 278 320 1.16E-11 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS10680 014044b1352568736c6d9186a32338bb 589 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 353 580 3.8E-77 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 Gene3D G3DSA:3.10.105.10 343 530 1.4E-43 T 09-03-2017 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 SUPERFAMILY SSF53850 176 557 2.71E-94 T 09-03-2017 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 SUPERFAMILY SSF53850 41 145 2.71E-94 T 09-03-2017 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 Gene3D G3DSA:3.90.76.10 54 220 1.8E-32 T 09-03-2017 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 Gene3D G3DSA:3.40.190.10 221 342 4.1E-24 T 09-03-2017 ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 481 2.2E-55 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS04210 8cde1135b7c06ad03a01fac79a9888db 560 PIRSF PIRSF002741 2 555 2.6E-73 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ARZXY2_RS18765 8706a97a52837943db9549f63029e556 117 Pfam PF07883 Cupin domain 41 107 1.5E-6 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS18765 8706a97a52837943db9549f63029e556 117 Gene3D G3DSA:2.60.120.10 26 108 3.3E-14 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS18765 8706a97a52837943db9549f63029e556 117 SUPERFAMILY SSF51182 34 109 2.31E-12 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 Pfam PF00128 Alpha amylase, catalytic domain 191 283 1.5E-4 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 SUPERFAMILY SSF51445 515 584 1.08E-121 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 SUPERFAMILY SSF51445 137 486 1.08E-121 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 SUPERFAMILY SSF81296 38 149 2.66E-11 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 Gene3D G3DSA:3.20.20.80 155 584 4.0E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 SMART SM00642 167 583 1.9E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 SUPERFAMILY SSF51011 602 657 1.8E-6 T 09-03-2017 ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 Gene3D G3DSA:2.60.40.1180 602 657 1.4E-7 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 Gene3D G3DSA:2.60.40.10 38 154 4.9E-16 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS14865 f6f705360e82738f9c13c33b17c53e84 704 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 135 702 7.0E-207 T 09-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Gene3D G3DSA:1.10.10.10 276 327 1.2E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Pfam PF04545 Sigma-70, region 4 371 424 3.1E-18 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 227 240 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 PRINTS PR00046 Major sigma-70 factor signature 411 422 3.2E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 PRINTS PR00046 Major sigma-70 factor signature 251 259 3.2E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 PRINTS PR00046 Major sigma-70 factor signature 227 240 3.2E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 PRINTS PR00046 Major sigma-70 factor signature 396 411 3.2E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 PRINTS PR00046 Major sigma-70 factor signature 375 387 3.2E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Pfam PF04539 Sigma-70 region 3 282 358 2.5E-28 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 SUPERFAMILY SSF88946 134 273 4.49E-52 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Pfam PF00140 Sigma-70 factor, region 1.2 137 170 2.4E-13 T 09-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 SUPERFAMILY SSF88659 334 435 2.03E-27 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 SUPERFAMILY SSF88659 276 349 1.87E-20 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 199 424 3.9E-36 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 199 435 3.9E-112 T 09-03-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Gene3D G3DSA:1.10.601.10 117 272 1.5E-68 T 09-03-2017 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 396 422 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 48 436 30.834 T 09-03-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Pfam PF04542 Sigma-70 region 2 203 272 2.3E-22 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10650 ab4bf562f2b26fe8ee0c2e71deaf837d 436 Gene3D G3DSA:1.10.10.10 365 436 1.6E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 SUPERFAMILY SSF52317 28 233 7.37E-53 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 Gene3D G3DSA:3.40.50.880 26 238 8.8E-79 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 29 232 9.5E-59 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 PIRSF PIRSF000495 27 236 1.8E-61 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 Pfam PF00117 Glutamine amidotransferase class-I 31 229 1.1E-16 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS11325 b593888ba69b30317669b8ef34698137 254 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 28 233 31.868 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 8 248 1.3E-94 T 09-03-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 2.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 SUPERFAMILY SSF51735 6 248 6.58E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.1E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 Gene3D G3DSA:3.40.50.720 2 248 3.6E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16810 7cd57b169019f7d2f720065179db4c36 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 8.3E-50 T 09-03-2017 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Pfam PF01380 SIS domain 476 606 3.8E-24 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Pfam PF01380 SIS domain 303 428 7.2E-32 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 SUPERFAMILY SSF53697 258 626 1.02E-108 T 09-03-2017 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Gene3D G3DSA:3.40.50.10490 456 626 5.6E-63 T 09-03-2017 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 SUPERFAMILY SSF56235 2 244 8.23E-64 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Gene3D G3DSA:3.40.50.10490 257 455 5.6E-72 T 09-03-2017 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 626 39.659 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Gene3D G3DSA:3.60.20.10 2 253 8.2E-73 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 626 4.1E-236 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ARZXY2_RS03755 dafed97a0b1e858194c46f3d41f916aa 626 Pfam PF13522 Glutamine amidotransferase domain 74 197 2.2E-20 T 09-03-2017 ARZXY2_RS05330 ba25321b3ab0e24f68a0b702e4afa8ec 247 Gene3D G3DSA:3.40.50.300 1 220 3.1E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05330 ba25321b3ab0e24f68a0b702e4afa8ec 247 SUPERFAMILY SSF52540 1 221 7.52E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05330 ba25321b3ab0e24f68a0b702e4afa8ec 247 Pfam PF00005 ABC transporter 17 159 1.6E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05330 ba25321b3ab0e24f68a0b702e4afa8ec 247 SMART SM00382 25 210 4.0E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Gene3D G3DSA:3.30.565.10 371 544 7.2E-44 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Gene3D G3DSA:3.40.50.2300 12 126 2.6E-7 T 09-03-2017 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 9.4E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 9.4E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 9.4E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 9.4E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Gene3D G3DSA:3.30.450.40 132 310 7.3E-15 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Pfam PF00512 His Kinase A (phospho-acceptor) domain 317 383 1.1E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SUPERFAMILY SSF52172 12 141 9.53E-13 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Gene3D G3DSA:1.10.287.130 311 370 2.7E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SUPERFAMILY SSF55781 136 297 2.04E-10 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SUPERFAMILY SSF47384 300 383 1.16E-19 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SMART SM00387 429 546 3.1E-35 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 430 543 5.0E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SUPERFAMILY SSF55874 375 544 4.85E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02345 10efbc4d995d2df677b2f076fb36ea42 547 SMART SM00388 317 385 4.2E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 162 249 2.7E-23 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 303 39.314 T 09-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Gene3D G3DSA:1.10.8.50 164 303 2.7E-46 T 09-03-2017 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 SUPERFAMILY SSF81624 2 134 1.96E-32 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 SMART SM01232 162 254 7.7E-41 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Gene3D G3DSA:3.20.190.10 2 134 2.4E-33 T 09-03-2017 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 ProSitePatterns PS01242 Zinc finger FPG-type signature. 278 302 - T 09-03-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 302 1.0E-78 T 09-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 SUPERFAMILY SSF46946 162 251 1.44E-25 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 SUPERFAMILY SSF57716 254 303 3.99E-16 T 09-03-2017 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Pfam PF06827 Zinc finger found in FPG and IleRS 275 303 8.1E-10 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 130 5.9E-31 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS05840 9a8e2c3a661bba25dd3316c1206c4315 312 SMART SM00898 2 132 2.7E-40 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 421 7.6E-127 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 Hamap MF_00220_B Dihydroorotase [pyrC]. 5 427 41.282 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 Pfam PF01979 Amidohydrolase family 49 421 1.3E-21 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 SUPERFAMILY SSF51338 6 52 3.16E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 SUPERFAMILY SSF51338 369 434 3.16E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 Gene3D G3DSA:3.20.20.140 67 409 1.0E-107 T 09-03-2017 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 SUPERFAMILY SSF51556 53 368 3.76E-101 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 09-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 ARZXY2_RS08125 345b7788fd7a412985a96aa68c45d892 451 Gene3D G3DSA:2.30.40.10 7 66 6.3E-17 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 SUPERFAMILY SSF52540 9 560 6.24E-230 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 6 562 46.502 T 09-03-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 108 118 - T 09-03-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Gene3D G3DSA:3.10.410.10 449 538 7.7E-37 T 09-03-2017 ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Gene3D G3DSA:3.40.50.300 253 447 6.8E-134 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Gene3D G3DSA:3.40.50.300 19 133 6.8E-134 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 1.6E-251 T 09-03-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ARZXY2_RS03795 8204941fc700b5f068ed72e68eb06d06 562 Gene3D G3DSA:3.30.1510.10 134 252 5.4E-53 T 09-03-2017 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 Gene3D G3DSA:1.10.1200.80 274 342 1.7E-16 T 09-03-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 SUPERFAMILY SSF51395 27 339 2.56E-78 T 09-03-2017 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 111 129 - T 09-03-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 20 339 1.7E-107 T 09-03-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 Pfam PF01207 Dihydrouridine synthase (Dus) 29 337 1.7E-96 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 PIRSF PIRSF006621 17 348 3.8E-98 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 ARZXY2_RS12185 5d5c75c219d7c1c5512350fd250ead8a 393 Gene3D G3DSA:3.20.20.70 24 265 1.4E-82 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS17670 9d3fd68ad1f3826ee9923386a6b3d686 235 Pfam PF01569 PAP2 superfamily 112 225 1.3E-18 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS17670 9d3fd68ad1f3826ee9923386a6b3d686 235 SMART SM00014 108 226 4.6E-12 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS17670 9d3fd68ad1f3826ee9923386a6b3d686 235 SUPERFAMILY SSF48317 34 226 2.49E-28 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS17670 9d3fd68ad1f3826ee9923386a6b3d686 235 Gene3D G3DSA:1.20.144.10 60 225 2.3E-23 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Gene3D G3DSA:1.20.140.10 233 384 6.4E-38 T 09-03-2017 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 1.4E-29 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 SUPERFAMILY SSF47203 236 384 2.9E-37 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 378 4.7E-28 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Gene3D G3DSA:2.40.110.10 129 230 6.0E-34 T 09-03-2017 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 SUPERFAMILY SSF56645 5 231 2.23E-70 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Gene3D G3DSA:1.10.540.10 5 128 8.6E-40 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS16685 4b568a5c845da24368f239e5ab4a0e36 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 219 1.4E-22 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 SMART SM00345 14 72 4.8E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 SMART SM00895 82 206 5.2E-22 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 Pfam PF07729 FCD domain 82 205 1.6E-22 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 SUPERFAMILY SSF46785 1 98 7.08E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 9.7E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.6E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.6E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 Gene3D G3DSA:1.10.10.10 3 72 1.5E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 SUPERFAMILY SSF48008 78 212 7.59E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS16675 14a15fb76bd49af86a7aaef817d3e2ea 239 Gene3D G3DSA:1.20.120.530 75 211 1.9E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 SMART SM01002 148 296 1.9E-89 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 Gene3D G3DSA:3.40.50.1770 200 353 2.1E-28 T 09-03-2017 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 SUPERFAMILY SSF51735 136 302 8.07E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 Gene3D G3DSA:3.40.50.1770 3 178 1.0E-63 T 09-03-2017 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 SMART SM01003 4 136 6.2E-77 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 364 8.8E-170 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 351 1.0E-80 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 PIRSF PIRSF000183 1 369 5.0E-168 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 Gene3D G3DSA:3.40.50.720 179 199 1.4E-4 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 SUPERFAMILY SSF52283 1 136 8.08E-63 T 09-03-2017 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 SUPERFAMILY SSF52283 304 359 8.08E-63 T 09-03-2017 ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 4.6E-46 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal ARZXY2_RS20150 7536c7a064f737914ded7a16446e19ae 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 09-03-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 18 341 6.4E-158 T 09-03-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 17 339 43.525 T 09-03-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 126 165 9.0E-18 T 09-03-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 Gene3D G3DSA:3.30.60.70 126 165 3.8E-5 T 09-03-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 SUPERFAMILY SSF51161 91 285 1.39E-37 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 Gene3D G3DSA:2.160.10.10 167 338 8.2E-31 T 09-03-2017 ARZXY2_RS04285 be4e12d63582b8a0feff3069e9588734 341 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 249 279 1.7E-12 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS04530 2944b1f6cc9dc42b22bf367ea7ff3bfd 138 SUPERFAMILY SSF46767 4 78 6.67E-14 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS04530 2944b1f6cc9dc42b22bf367ea7ff3bfd 138 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 6 78 2.6E-15 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS04530 2944b1f6cc9dc42b22bf367ea7ff3bfd 138 Gene3D G3DSA:1.10.10.10 7 78 6.8E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 09-03-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 PIRSF PIRSF001553 1 299 3.1E-116 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 4.2E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 4.2E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 4.2E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 4.2E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 Gene3D G3DSA:3.40.50.720 2 131 3.9E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 SUPERFAMILY SSF51735 1 118 2.91E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 Pfam PF02629 CoA binding domain 6 103 1.8E-23 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 Gene3D G3DSA:3.40.50.261 132 297 2.1E-65 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 SMART SM00881 4 104 6.4E-29 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 Pfam PF00549 CoA-ligase 163 280 2.1E-14 T 09-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 SUPERFAMILY SSF52210 134 296 4.97E-47 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 163 190 - T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS14100 3dae4023d7d462d9e5c40a54acd1644d 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 296 2.5E-125 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 2.0E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 Gene3D G3DSA:1.10.10.10 3 66 1.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 SUPERFAMILY SSF48008 71 207 1.15E-17 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 SUPERFAMILY SSF46785 3 69 2.32E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 SMART SM00345 7 65 5.4E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.0E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.0E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 SMART SM00895 75 201 2.0E-8 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 Pfam PF07729 FCD domain 75 201 4.2E-17 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS11075 540b5997376059d51efa03dccc07d69a 213 Gene3D G3DSA:1.20.120.530 68 210 4.2E-19 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS08590 bc01153892e334bcfaf88971622f9c48 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 22.111 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 ARZXY2_RS08590 bc01153892e334bcfaf88971622f9c48 115 Pfam PF13397 RNA polymerase-binding protein 4 106 3.3E-39 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 6.9E-37 T 09-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Gene3D G3DSA:2.40.50.140 1 64 3.1E-20 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Pfam PF14520 Helix-hairpin-helix domain 71 127 6.9E-14 T 09-03-2017 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 SUPERFAMILY SSF46929 150 201 1.02E-9 T 09-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Gene3D G3DSA:1.10.8.10 142 201 2.1E-11 T 09-03-2017 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 SUPERFAMILY SSF47781 64 132 1.04E-17 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 SUPERFAMILY SSF50249 1 62 1.2E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 26.631 T 09-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 SMART SM00278 107 126 0.41 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 SMART SM00278 72 91 5.5 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Pfam PF01330 RuvA N terminal domain 2 61 1.6E-16 T 09-03-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Pfam PF07499 RuvA, C-terminal domain 150 200 6.4E-5 T 09-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 ARZXY2_RS07975 57c35b7210b3fe0e7b96b62b2ca1fcb4 214 Gene3D G3DSA:1.10.150.20 66 134 4.7E-24 T 09-03-2017 ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 Gene3D G3DSA:3.40.50.720 4 248 6.2E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 5.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 247 1.4E-55 T 09-03-2017 ARZXY2_RS16990 614fc19a2e7949b874249cfe8c41453b 258 SUPERFAMILY SSF51735 13 248 5.35E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 PRINTS PR00332 Histidine triad family signature 25 43 5.6E-12 T 09-03-2017 IPR001310 Histidine triad (HIT) protein ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 PRINTS PR00332 Histidine triad family signature 87 97 5.6E-12 T 09-03-2017 IPR001310 Histidine triad (HIT) protein ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 PRINTS PR00332 Histidine triad family signature 4 20 5.6E-12 T 09-03-2017 IPR001310 Histidine triad (HIT) protein ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 Gene3D G3DSA:3.30.428.10 2 130 5.5E-27 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 SUPERFAMILY SSF54197 3 131 2.01E-32 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS05110 a174eb6393641ff52cb5b10aa9adebca 142 Pfam PF01230 HIT domain 11 101 1.5E-18 T 09-03-2017 IPR001310 Histidine triad (HIT) protein ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 SMART SM00640 42 479 1.7E-103 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 SUPERFAMILY SSF75005 34 362 6.28E-62 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 405 479 3.9E-8 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 SUPERFAMILY SSF49899 361 516 7.91E-29 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 Gene3D G3DSA:2.60.120.560 357 515 3.6E-26 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS16015 0abc470fae0fbcd56920aa9c60b2f7ec 519 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 42 351 9.4E-60 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 Pfam PF03129 Anticodon binding domain 356 427 3.6E-7 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 429 3.8E-105 T 09-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 PIRSF PIRSF001549 1 440 8.4E-97 T 09-03-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 Gene3D G3DSA:3.40.50.800 353 430 1.4E-14 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 Pfam PF13393 Histidyl-tRNA synthetase 9 336 1.6E-27 T 09-03-2017 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 SUPERFAMILY SSF55681 7 344 8.09E-60 T 09-03-2017 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 Gene3D G3DSA:3.30.930.10 6 193 8.8E-74 T 09-03-2017 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 Gene3D G3DSA:3.30.930.10 245 344 8.8E-74 T 09-03-2017 ARZXY2_RS08020 f36c17949488f0f486a3ce7188084fc6 448 SUPERFAMILY SSF52954 353 430 6.05E-14 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 22 453 37.616 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 387 405 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 276 295 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 346 371 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 254 275 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 189 215 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 51 75 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PRINTS PR00083 Histidinol dehydrogenase signature 152 178 1.9E-66 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 PIRSF PIRSF000099 18 456 3.0E-142 T 09-03-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 Gene3D G3DSA:3.40.50.1980 45 264 1.5E-68 T 09-03-2017 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 254 286 - T 09-03-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 Pfam PF00815 Histidinol dehydrogenase 40 453 1.3E-150 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 51 452 2.9E-138 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 ARZXY2_RS10775 e31dca03cac302cd1003c0e4b0837da6 457 SUPERFAMILY SSF53720 44 453 1.26E-67 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS18025 afcd7558c60299b4c66cab6d0984a46d 162 Gene3D G3DSA:3.90.80.10 4 158 6.6E-52 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 ARZXY2_RS18025 afcd7558c60299b4c66cab6d0984a46d 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.394 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 ARZXY2_RS18025 afcd7558c60299b4c66cab6d0984a46d 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 ARZXY2_RS18025 afcd7558c60299b4c66cab6d0984a46d 162 SUPERFAMILY SSF50324 4 157 5.1E-55 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 ARZXY2_RS18025 afcd7558c60299b4c66cab6d0984a46d 162 Pfam PF00719 Inorganic pyrophosphatase 5 157 3.1E-52 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 SUPERFAMILY SSF51735 17 144 3.75E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 Pfam PF02254 TrkA-N domain 17 132 1.5E-21 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 Gene3D G3DSA:3.40.50.720 16 146 2.6E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 SUPERFAMILY SSF116726 142 225 9.29E-15 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 Pfam PF02080 TrkA-C domain 167 226 1.9E-6 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS01920 3cdabe4234db7003912988794b812b64 228 Gene3D G3DSA:3.30.70.1450 165 226 2.4E-11 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 Gene3D G3DSA:2.40.270.10 945 1058 1.0E-14 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 Gene3D G3DSA:2.40.40.20 1337 1437 2.2E-14 T 09-03-2017 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 SUPERFAMILY SSF64484 1234 1281 1.47E-17 T 09-03-2017 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 SUPERFAMILY SSF64484 1308 1442 1.47E-17 T 09-03-2017 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 SUPERFAMILY SSF64484 945 1058 7.94E-12 T 09-03-2017 ARZXY2_RS06790 fc05789cd6da22bf6357aeeabbf34772 1853 Pfam PF00562 RNA polymerase Rpb2, domain 6 976 1057 2.3E-5 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS04770 0514f300bcacac58f920f89b3dbc159f 242 SUPERFAMILY SSF69754 3 112 4.84E-23 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ARZXY2_RS04770 0514f300bcacac58f920f89b3dbc159f 242 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 157 211 1.0E-18 T 09-03-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal ARZXY2_RS04770 0514f300bcacac58f920f89b3dbc159f 242 Gene3D G3DSA:3.30.160.100 1 101 5.1E-23 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ARZXY2_RS04770 0514f300bcacac58f920f89b3dbc159f 242 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 99 3.3E-19 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ARZXY2_RS04770 0514f300bcacac58f920f89b3dbc159f 242 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 103 2.2E-21 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 ARZXY2_RS20610 d6c0764b2f2360786e5df14ca7260204 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.2E-23 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS20610 d6c0764b2f2360786e5df14ca7260204 78 Gene3D G3DSA:2.30.170.40 2 77 4.0E-30 T 09-03-2017 ARZXY2_RS20610 d6c0764b2f2360786e5df14ca7260204 78 SUPERFAMILY SSF143800 2 77 4.91E-25 T 09-03-2017 ARZXY2_RS20610 d6c0764b2f2360786e5df14ca7260204 78 Pfam PF00830 Ribosomal L28 family 4 60 6.3E-22 T 09-03-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS20610 d6c0764b2f2360786e5df14ca7260204 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 18.55 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 Pfam PF00075 RNase H 7 138 9.7E-27 T 09-03-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 Pfam PF14534 Domain of unknown function (DUF4440) 241 337 1.4E-10 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 SUPERFAMILY SSF53098 3 140 5.69E-40 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 Gene3D G3DSA:3.30.420.10 2 140 8.0E-46 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 Gene3D G3DSA:3.10.450.50 237 344 1.2E-10 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS14315 7901ed862b895406f57d8d6399a3ff15 346 SUPERFAMILY SSF54427 237 344 3.84E-13 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Pfam PF13361 UvrD-like helicase C-terminal domain 286 415 1.5E-15 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Pfam PF13361 UvrD-like helicase C-terminal domain 452 561 3.5E-23 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 SUPERFAMILY SSF47819 624 702 6.54E-23 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Pfam PF00570 HRDC domain 634 700 1.4E-22 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Pfam PF00580 UvrD/REP helicase N-terminal domain 133 279 2.0E-26 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 83 1.1E-20 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Gene3D G3DSA:3.40.50.300 15 284 5.6E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Gene3D G3DSA:3.40.50.300 498 584 1.5E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Gene3D G3DSA:3.40.50.300 290 409 1.5E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 SUPERFAMILY SSF52540 10 583 6.44E-122 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 SMART SM00341 630 706 8.2E-14 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 ARZXY2_RS04555 ece8fc70f1444d93d7f84369648766c8 706 Gene3D G3DSA:1.10.150.80 633 702 1.5E-14 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 SUPERFAMILY SSF52540 54 300 4.24E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 96 227 2.6E-18 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 272 284 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 215 234 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 94 109 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 177 189 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 54 68 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 146 165 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 198 215 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 PRINTS PR00819 CbxX/CfqX superfamily signature 132 146 2.7E-54 T 09-03-2017 IPR000641 CbxX/CfqX GO:0005524 ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 Gene3D G3DSA:3.40.50.300 53 243 1.9E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09490 526caffb902c30e522a31fa33b4ab461 344 SMART SM00382 91 230 4.9E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17975 c29fa83266cd6947924693b3d5cedb79 179 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 137 2.6E-36 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17975 c29fa83266cd6947924693b3d5cedb79 179 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 93 104 - T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17975 c29fa83266cd6947924693b3d5cedb79 179 SUPERFAMILY SSF55083 6 153 1.06E-47 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17975 c29fa83266cd6947924693b3d5cedb79 179 Gene3D G3DSA:3.30.70.560 7 153 3.3E-53 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17975 c29fa83266cd6947924693b3d5cedb79 179 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 137 9.7E-42 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS16005 83433f817d25333c5aa5828e97770664 445 Gene3D G3DSA:3.40.190.10 58 174 4.3E-17 T 09-03-2017 ARZXY2_RS16005 83433f817d25333c5aa5828e97770664 445 Gene3D G3DSA:3.40.190.10 175 353 2.6E-30 T 09-03-2017 ARZXY2_RS16005 83433f817d25333c5aa5828e97770664 445 Pfam PF01547 Bacterial extracellular solute-binding protein 59 350 5.7E-27 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS16005 83433f817d25333c5aa5828e97770664 445 SUPERFAMILY SSF53850 19 437 6.52E-62 T 09-03-2017 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 Pfam PF00005 ABC transporter 457 605 3.8E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 Gene3D G3DSA:3.40.50.300 439 670 4.8E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 SUPERFAMILY SSF90123 149 425 2.88E-84 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 SUPERFAMILY SSF90123 68 110 2.88E-84 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 SUPERFAMILY SSF52540 432 676 5.43E-89 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 ProSitePatterns PS00211 ABC transporters family signature. 577 591 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 SMART SM00382 465 651 3.5E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 Pfam PF00664 ABC transporter transmembrane region 86 393 1.8E-60 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 Gene3D G3DSA:1.20.1560.10 151 425 1.4E-88 T 09-03-2017 ARZXY2_RS13960 968a2d9f7aec88d6dd7cb904db4c49d3 694 Gene3D G3DSA:1.20.1560.10 71 115 1.4E-88 T 09-03-2017 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 116 608 1.7E-230 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 337 1.6E-45 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 643 36.798 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 Gene3D G3DSA:3.40.50.300 161 346 1.1E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 SMART SM00382 201 340 4.5E-24 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 Gene3D G3DSA:1.10.8.60 347 412 8.4E-23 T 09-03-2017 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 SUPERFAMILY SSF52540 161 409 1.1E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 Pfam PF01434 Peptidase family M41 400 607 3.7E-80 T 09-03-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 SUPERFAMILY SSF140990 419 615 6.15E-72 T 09-03-2017 ARZXY2_RS17995 3a6e79b70e930263241e6cf87bf3c249 689 ProSitePatterns PS00674 AAA-protein family signature. 308 326 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 Gene3D G3DSA:3.40.190.10 98 187 1.3E-19 T 09-03-2017 ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 Gene3D G3DSA:3.40.190.10 188 276 2.5E-23 T 09-03-2017 ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 SUPERFAMILY SSF53850 99 307 5.89E-34 T 09-03-2017 ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 Gene3D G3DSA:1.10.10.10 10 95 2.9E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 9.8E-21 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 Pfam PF03466 LysR substrate binding domain 97 302 1.7E-36 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS16900 85a98b55fde43d0cf9a2a71dd3c896dc 312 SUPERFAMILY SSF46785 4 117 3.01E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00820 93adc5b4a3888e2ad27649dc973e7a97 275 SUPERFAMILY SSF52540 11 242 8.6E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00820 93adc5b4a3888e2ad27649dc973e7a97 275 SMART SM00382 37 242 3.6E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00820 93adc5b4a3888e2ad27649dc973e7a97 275 Pfam PF00005 ABC transporter 30 186 2.7E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00820 93adc5b4a3888e2ad27649dc973e7a97 275 Gene3D G3DSA:3.40.50.300 9 250 1.6E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Pfam PF01799 [2Fe-2S] binding domain 70 138 1.0E-25 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:1.10.150.120 72 139 6.5E-26 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 345 882 1.4E-153 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 SUPERFAMILY SSF54292 3 84 2.23E-18 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.10.20.30 3 71 2.0E-23 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 197 311 4.3E-25 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 473 548 1.2E-37 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 313 366 1.2E-37 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 SUPERFAMILY SSF54665 179 332 2.36E-38 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 367 471 1.4E-37 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.90.1170.50 179 311 3.2E-37 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 645 789 4.8E-30 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 SUPERFAMILY SSF56003 316 943 4.58E-172 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 09-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 549 644 3.0E-50 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Gene3D G3DSA:3.30.365.10 799 944 3.0E-50 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 SMART SM01008 197 312 2.8E-43 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 56 1.1E-5 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS01625 9e0b79100306286d83863afa1d32a18d 949 SUPERFAMILY SSF47741 76 145 1.15E-23 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 214 1.5E-62 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 SUPERFAMILY SSF53335 1 211 1.36E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 Gene3D G3DSA:3.40.50.150 1 212 5.1E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 214 33.13 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 122 136 - T 09-03-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 ARZXY2_RS02810 f668c14026cb42ca4900a79a81b179e2 241 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 1 214 4.4E-73 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 SMART SM00388 235 300 1.6E-8 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 452 6.2E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 Pfam PF00672 HAMP domain 164 229 8.3E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 Gene3D G3DSA:3.30.565.10 319 456 2.6E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 SMART SM00304 182 234 8.5E-6 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 8.4E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 8.4E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 SMART SM00387 357 466 5.4E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 SUPERFAMILY SSF47384 219 298 3.73E-10 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 6.3E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 SUPERFAMILY SSF55874 317 461 2.88E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15560 7b4259f5ee138a4928b6ec8e23d8bcaa 468 Gene3D G3DSA:1.10.287.130 225 295 7.3E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 SUPERFAMILY SSF46785 2 83 2.79E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 332 1.3E-85 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 326 24.968 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 Gene3D G3DSA:1.10.10.10 2 84 1.9E-35 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 Pfam PF08220 DeoR-like helix-turn-helix domain 19 57 6.4E-5 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 SUPERFAMILY SSF55781 71 334 1.96E-49 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 Pfam PF01628 HrcA protein C terminal domain 103 319 2.5E-54 T 09-03-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 PIRSF PIRSF005485 1 335 1.8E-93 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 ARZXY2_RS08275 522363dce6443deb48bdb3ca6d09b88b 335 Gene3D G3DSA:3.30.450.40 197 333 1.3E-30 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 SUPERFAMILY SSF53383 59 508 7.09E-117 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 Gene3D G3DSA:3.90.1150.10 391 509 4.2E-37 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 Gene3D G3DSA:1.20.1650.10 30 104 1.0E-22 T 09-03-2017 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 Gene3D G3DSA:3.40.640.10 115 390 3.5E-97 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 107 440 3.6E-70 T 09-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 145 164 4.2E-5 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 378 393 4.2E-5 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 ARZXY2_RS17390 3b041f951515e34d9c48da536eacd13d 520 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 421 440 4.2E-5 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 ARZXY2_RS05050 2d1b936b0a9792a1dc399e60fcbf0459 209 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 20 187 2.8E-11 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS05050 2d1b936b0a9792a1dc399e60fcbf0459 209 Gene3D G3DSA:3.40.50.1110 15 197 2.1E-32 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS05050 2d1b936b0a9792a1dc399e60fcbf0459 209 SUPERFAMILY SSF52266 14 195 1.83E-26 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 7.7E-126 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 40.51 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 SUPERFAMILY SSF52210 231 385 2.62E-41 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 SUPERFAMILY SSF56059 3 226 1.77E-64 T 09-03-2017 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Gene3D G3DSA:3.40.50.261 232 385 1.3E-52 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Pfam PF08442 ATP-grasp domain 2 194 5.5E-69 T 09-03-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Pfam PF00549 CoA-ligase 256 374 5.4E-13 T 09-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 PIRSF PIRSF001554 1 388 3.6E-137 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 09-03-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Gene3D G3DSA:3.30.1490.20 22 87 1.2E-19 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS14105 660537bb62c1f635a33dffbddb741d9c 389 Gene3D G3DSA:3.30.470.20 88 230 5.2E-52 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 SUPERFAMILY SSF54368 12 119 1.31E-14 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 SUPERFAMILY SSF55931 122 461 9.81E-105 T 09-03-2017 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 Gene3D G3DSA:3.10.20.70 12 124 5.7E-13 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 SMART SM01230 121 377 9.0E-104 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 Gene3D G3DSA:3.30.590.10 125 449 7.6E-104 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 ARZXY2_RS07165 6c39824a1529113a9dc20f5478825c04 463 Pfam PF00120 Glutamine synthetase, catalytic domain 122 459 7.1E-103 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 SMART SM00387 62 157 7.1E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 SUPERFAMILY SSF55874 31 156 2.36E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 98 112 7.3E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 118 136 7.3E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 142 155 7.3E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 66 156 5.3E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS01535 8f7e3fb575ad803b274dc10d403b16c7 157 Gene3D G3DSA:3.30.565.10 22 156 1.5E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 SUPERFAMILY SSF53927 24 282 2.59E-73 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 283 32.451 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 Gene3D G3DSA:3.40.140.10 143 283 1.2E-51 T 09-03-2017 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 Gene3D G3DSA:3.10.20.10 36 126 1.2E-22 T 09-03-2017 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 PIRSF PIRSF015626 1 286 1.0E-81 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 29 283 6.6E-44 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS14205 9b9c7cf4fc5990a0431aebda31b1e390 292 Pfam PF02634 FdhD/NarQ family 34 282 2.6E-76 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS09385 457559abbc5edb00df8e38cf1fd19b41 261 Gene3D G3DSA:3.90.850.10 1 260 1.6E-84 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09385 457559abbc5edb00df8e38cf1fd19b41 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 101 257 5.7E-6 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09385 457559abbc5edb00df8e38cf1fd19b41 261 SUPERFAMILY SSF56529 2 260 1.02E-77 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09385 457559abbc5edb00df8e38cf1fd19b41 261 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 260 7.6E-114 T 09-03-2017 IPR012690 2-oxo-hepta-3-ene-1,7-dioic acid hydratase GO:0019439 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 Pfam PF00164 Ribosomal protein S12/S23 3 122 1.2E-42 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PIRSF PIRSF002133 1 124 5.5E-53 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.1E-56 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 6.6E-66 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 Gene3D G3DSA:2.40.50.140 2 123 1.1E-62 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.327 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03460 a34e047f60b1933de4b4e240aecf0166 124 SUPERFAMILY SSF50249 2 123 1.63E-51 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 161 31.083 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 Gene3D G3DSA:3.40.50.7700 6 164 1.6E-69 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 PIRSF PIRSF001338 5 172 6.8E-64 T 09-03-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 157 4.4E-61 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 Pfam PF00731 AIR carboxylase 10 148 1.0E-62 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 SUPERFAMILY SSF52255 8 162 4.84E-62 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS12925 d8c9cfcdbf92828019ce525692d5672b 187 SMART SM01001 8 157 3.8E-90 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 ARZXY2_RS16805 a50139923858e801a05eac3bcce9a803 479 ProSitePatterns PS00218 Amino acid permeases signature. 53 83 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS16805 a50139923858e801a05eac3bcce9a803 479 Pfam PF00324 Amino acid permease 28 465 7.2E-112 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS16805 a50139923858e801a05eac3bcce9a803 479 PIRSF PIRSF006060 14 477 1.9E-74 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Gene3D G3DSA:3.30.1360.10 7 61 1.0E-10 T 09-03-2017 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 9.2E-24 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 SUPERFAMILY SSF47789 248 316 2.49E-24 T 09-03-2017 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 6.8E-19 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.5E-114 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 33.985 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 SMART SM00662 18 225 4.0E-90 T 09-03-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Gene3D G3DSA:2.170.120.12 62 168 3.0E-46 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 313 3.0E-30 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 1.4E-26 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 SUPERFAMILY SSF55257 16 48 2.94E-23 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 SUPERFAMILY SSF55257 170 220 2.94E-23 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 Gene3D G3DSA:1.10.150.20 247 317 5.4E-32 T 09-03-2017 ARZXY2_RS03670 2fbb1bc2478ced23656e0ce15182ae0e 336 SUPERFAMILY SSF56553 48 169 2.35E-42 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS01245 8459f273086b7da83dd309eddd7568b0 678 Pfam PF13673 Acetyltransferase (GNAT) domain 52 134 4.4E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS01245 8459f273086b7da83dd309eddd7568b0 678 Gene3D G3DSA:3.40.50.1010 171 297 4.9E-5 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS01245 8459f273086b7da83dd309eddd7568b0 678 Gene3D G3DSA:3.40.630.30 13 133 3.7E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS01245 8459f273086b7da83dd309eddd7568b0 678 SUPERFAMILY SSF55729 12 133 1.2E-13 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 SUPERFAMILY SSF55424 260 395 3.95E-36 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 SUPERFAMILY SSF51905 42 298 1.59E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 30 237 2.6E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Gene3D G3DSA:3.50.50.60 4 55 6.7E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Gene3D G3DSA:3.50.50.60 181 248 6.7E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Gene3D G3DSA:3.30.390.30 259 390 9.8E-46 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 217 224 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 82 107 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 380 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 188 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 353 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 56 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 281 3.4E-45 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Gene3D G3DSA:3.50.50.60 62 180 2.2E-25 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 62 2.9E-26 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 82 100 2.9E-26 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 189 2.9E-26 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 224 2.9E-26 T 09-03-2017 ARZXY2_RS19315 35cffccbbb703ce04597c37553a15f33 401 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 264 385 7.5E-30 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Gene3D G3DSA:3.40.50.300 483 579 1.5E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Gene3D G3DSA:3.40.50.300 445 446 1.5E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Gene3D G3DSA:3.40.50.300 333 403 1.5E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Pfam PF13245 Part of AAA domain 344 407 3.3E-9 T 09-03-2017 ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Pfam PF00580 UvrD/REP helicase N-terminal domain 447 562 1.2E-8 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 SUPERFAMILY SSF52540 331 619 3.44E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 SUPERFAMILY SSF52540 656 874 3.44E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Pfam PF13538 UvrD-like helicase C-terminal domain 823 866 2.5E-10 T 09-03-2017 IPR027785 UvrD-like helicase C-terminal domain ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Gene3D G3DSA:3.40.50.300 580 690 3.5E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06590 00a0126fa24c15d904a88433b2fec396 929 Gene3D G3DSA:3.40.50.300 814 877 3.5E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SUPERFAMILY SSF63825 47 240 9.94E-6 T 09-03-2017 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SMART SM00060 1473 1547 2.9E-10 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SMART SM00060 1660 1739 1.6E-4 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SMART SM00060 1562 1642 0.054 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 Gene3D G3DSA:2.60.40.10 1471 1554 1.1E-17 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 Gene3D G3DSA:2.60.40.10 1654 1753 3.5E-10 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SUPERFAMILY SSF49265 1458 1569 2.04E-19 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 Pfam PF00041 Fibronectin type III domain 1569 1641 2.7E-7 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 Pfam PF00041 Fibronectin type III domain 1475 1550 3.7E-8 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 SUPERFAMILY SSF49265 1562 1749 1.26E-22 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12450 eb318a9764a1c33c5d7cbbc05757d80e 2033 Gene3D G3DSA:2.60.40.10 1562 1653 4.8E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS11590 4299df2cbb25539eb48aeb558aad1252 253 Gene3D G3DSA:3.40.50.300 8 232 2.6E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11590 4299df2cbb25539eb48aeb558aad1252 253 Pfam PF00005 ABC transporter 31 168 3.4E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS11590 4299df2cbb25539eb48aeb558aad1252 253 SMART SM00382 40 224 5.3E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS11590 4299df2cbb25539eb48aeb558aad1252 253 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS11590 4299df2cbb25539eb48aeb558aad1252 253 SUPERFAMILY SSF52540 15 229 9.61E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 SUPERFAMILY SSF52540 68 244 3.5E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 SUPERFAMILY SSF52540 275 422 3.5E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 Pfam PF09369 Domain of unknown function (DUF1998) 672 751 1.8E-18 T 09-03-2017 IPR018973 DEAD/DEAH-box helicase, putative ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 Pfam PF00270 DEAD/DEAH box helicase 58 242 9.0E-20 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 SMART SM00487 52 271 2.2E-24 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 Gene3D G3DSA:3.40.50.300 298 438 2.1E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 Pfam PF00271 Helicase conserved C-terminal domain 302 411 9.3E-10 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 Gene3D G3DSA:3.40.50.300 40 245 5.3E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 20 778 0.0 T 09-03-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria ARZXY2_RS01860 9500706fdef3d1655d695d435b1e9525 780 SMART SM00490 333 411 4.6E-13 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 Gene3D G3DSA:3.40.190.10 46 127 1.4E-39 T 09-03-2017 ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 Gene3D G3DSA:3.40.190.10 228 271 1.4E-39 T 09-03-2017 ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 SMART SM00062 49 269 2.1E-73 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 267 1.0E-59 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 SUPERFAMILY SSF53850 8 270 1.92E-64 T 09-03-2017 ARZXY2_RS14175 132f7baf89392352efc4522315ebf504 272 Gene3D G3DSA:3.40.190.10 128 227 1.3E-27 T 09-03-2017 ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 Pfam PF07690 Major Facilitator Superfamily 23 411 6.5E-60 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 SUPERFAMILY SSF103473 8 200 4.05E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 SUPERFAMILY SSF103473 250 446 4.05E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 419 1.5E-70 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 Gene3D G3DSA:1.20.1250.20 17 200 1.4E-28 T 09-03-2017 ARZXY2_RS17900 4eeff79c45c6af5a7cf1e3ac428e5496 457 Gene3D G3DSA:1.20.1250.20 263 449 1.2E-22 T 09-03-2017 ARZXY2_RS15495 7c0e2b34d1915264b3bcd286f8d34324 142 SUPERFAMILY SSF55298 13 128 1.32E-33 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS15495 7c0e2b34d1915264b3bcd286f8d34324 142 Pfam PF01042 Endoribonuclease L-PSP 15 126 4.7E-27 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family ARZXY2_RS15495 7c0e2b34d1915264b3bcd286f8d34324 142 Gene3D G3DSA:3.30.1330.40 13 127 9.8E-35 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 18 260 2.4E-112 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 261 436 4.2E-83 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 PIRSF PIRSF001362 7 437 1.9E-235 T 09-03-2017 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 ProSitePatterns PS00161 Isocitrate lyase signature. 198 203 - T 09-03-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 SUPERFAMILY SSF51621 12 436 1.39E-156 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 Gene3D G3DSA:3.20.20.60 12 417 3.2E-167 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 Pfam PF00463 Isocitrate lyase family 21 260 2.5E-56 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 ARZXY2_RS15590 229d29329dd6d9a99e3adaf07af5e629 437 Pfam PF00463 Isocitrate lyase family 262 430 4.4E-44 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 ARZXY2_RS05665 8c6fda77877822488d7576235be87c80 264 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS05665 8c6fda77877822488d7576235be87c80 264 SUPERFAMILY SSF52540 29 246 2.2E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05665 8c6fda77877822488d7576235be87c80 264 SMART SM00382 56 242 9.5E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05665 8c6fda77877822488d7576235be87c80 264 Gene3D G3DSA:3.40.50.300 28 246 4.9E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05665 8c6fda77877822488d7576235be87c80 264 Pfam PF00005 ABC transporter 47 193 5.8E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 200 248 - T 09-03-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 264 2.7E-50 T 09-03-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 SUPERFAMILY SSF49503 131 275 3.34E-40 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 137 254 5.2E-21 T 09-03-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 Gene3D G3DSA:2.60.40.420 135 266 2.6E-41 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 Gene3D G3DSA:1.10.287.90 44 127 1.3E-12 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 237 254 3.6E-11 T 09-03-2017 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 199 219 3.6E-11 T 09-03-2017 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 219 236 3.6E-11 T 09-03-2017 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 132 151 3.6E-11 T 09-03-2017 ARZXY2_RS08380 b324f985352a93348228db5a8b64d706 290 SUPERFAMILY SSF81464 28 129 5.07E-15 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 SUPERFAMILY SSF46785 814 878 7.75E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 SMART SM00382 549 747 0.0039 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 Pfam PF01580 FtsK/SpoIIIE family 514 714 1.9E-55 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 Gene3D G3DSA:3.40.50.300 488 781 6.1E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 Pfam PF09397 Ftsk gamma domain 817 874 1.4E-21 T 09-03-2017 IPR018541 FtsK gamma domain ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 SUPERFAMILY SSF52540 488 787 7.59E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11415 76ee8b11f2da3c8e7716e808a98858be 955 SMART SM00843 813 877 3.8E-28 T 09-03-2017 IPR018541 FtsK gamma domain ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 Gene3D G3DSA:3.40.1030.10 86 351 3.3E-103 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 16 349 34.775 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 SUPERFAMILY SSF47648 14 80 2.49E-19 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 Pfam PF00591 Glycosyl transferase family, a/b domain 85 339 5.3E-80 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 17 76 1.3E-19 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 Gene3D G3DSA:1.20.970.10 17 81 4.0E-26 T 09-03-2017 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 SUPERFAMILY SSF52418 85 352 3.53E-82 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS08425 4bc06be32d7bd67c352c78b946f5bf61 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 19 348 1.1E-109 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 ARZXY2_RS16795 d4791d4b92c8c5794da2dc466d3a9f82 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 132 1.0E-13 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase ARZXY2_RS16795 d4791d4b92c8c5794da2dc466d3a9f82 143 SUPERFAMILY SSF55961 3 139 1.48E-22 T 09-03-2017 ARZXY2_RS16795 d4791d4b92c8c5794da2dc466d3a9f82 143 Gene3D G3DSA:3.30.530.20 3 100 2.6E-15 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 Gene3D G3DSA:3.10.170.10 51 168 6.8E-44 T 09-03-2017 IPR013856 Peptidase M4 domain GO:0004222 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 58 164 1.4E-28 T 09-03-2017 IPR013856 Peptidase M4 domain GO:0004222 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 SUPERFAMILY SSF55486 47 336 6.96E-81 T 09-03-2017 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 167 336 2.9E-55 T 09-03-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 176 187 7.6E-29 T 09-03-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 257 273 7.6E-29 T 09-03-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 155 171 7.6E-29 T 09-03-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 119 139 7.6E-29 T 09-03-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 ARZXY2_RS05135 ae239cec5c01ec98daf50931ca51e557 338 Gene3D G3DSA:1.10.390.10 169 336 5.7E-53 T 09-03-2017 ARZXY2_RS19405 d9b818547410a59dbf56910bf9ef59d0 127 Gene3D G3DSA:3.30.1330.40 1 127 4.1E-39 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS19405 d9b818547410a59dbf56910bf9ef59d0 127 SUPERFAMILY SSF55298 1 126 1.29E-33 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS19405 d9b818547410a59dbf56910bf9ef59d0 127 Pfam PF01042 Endoribonuclease L-PSP 11 125 1.2E-28 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 188 9.2E-37 T 09-03-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 SUPERFAMILY SSF100939 1 263 1.8E-59 T 09-03-2017 IPR016194 SPOC-like, C-terminal domain ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 258 32.393 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 260 1.7E-85 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 PIRSF PIRSF006493 1 294 4.0E-91 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 SMART SM00559 52 179 2.0E-36 T 09-03-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 ARZXY2_RS17280 7589611bccde41876745aa5b4a5d7e14 294 Gene3D G3DSA:2.40.290.10 4 178 1.5E-11 T 09-03-2017 IPR016194 SPOC-like, C-terminal domain ARZXY2_RS03850 638535bbd0de7bf618a634875957e886 376 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 240 352 9.7E-10 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal ARZXY2_RS03850 638535bbd0de7bf618a634875957e886 376 Gene3D G3DSA:3.30.1220.10 235 352 9.7E-4 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal ARZXY2_RS03850 638535bbd0de7bf618a634875957e886 376 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 48 142 1.2E-4 T 09-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain ARZXY2_RS03850 638535bbd0de7bf618a634875957e886 376 SMART SM00833 239 353 4.1E-17 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal ARZXY2_RS03850 638535bbd0de7bf618a634875957e886 376 Gene3D G3DSA:3.40.50.300 37 131 1.4E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 SUPERFAMILY SSF46609 3 88 6.81E-32 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 8.0E-31 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 Gene3D G3DSA:1.10.287.990 21 84 4.7E-24 T 09-03-2017 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PIRSF PIRSF000349 1 202 6.4E-77 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 SUPERFAMILY SSF54719 84 197 3.67E-44 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 7.7E-36 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 09-03-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 2.7E-21 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 2.7E-21 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 2.7E-21 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 2.7E-21 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS09080 996777c43e7f4a953615d1603e103e6e 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 2.7E-21 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 7 864 1.5E-290 T 09-03-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 6.4E-18 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 6.4E-18 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 272 282 6.4E-18 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 321 6.4E-18 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 325 337 6.4E-18 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 Gene3D G3DSA:1.10.390.10 319 464 5.4E-42 T 09-03-2017 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 SUPERFAMILY SSF63737 8 201 4.45E-33 T 09-03-2017 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 Pfam PF01433 Peptidase family M1 21 398 3.1E-64 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 SUPERFAMILY SSF55486 220 461 6.01E-73 T 09-03-2017 ARZXY2_RS08870 6f78f65ef80c661af3f6b352215c3654 871 Pfam PF11838 ERAP1-like C-terminal domain 539 856 7.2E-48 T 09-03-2017 IPR024571 ERAP1-like C-terminal domain ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Gene3D G3DSA:1.10.1740.10 309 388 4.8E-31 T 09-03-2017 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 PIRSF PIRSF006205 3 393 9.2E-138 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 6 388 43.201 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 387 1.3E-115 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 SUPERFAMILY SSF51735 2 156 1.87E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Pfam PF13288 DXP reductoisomerase C-terminal domain 268 383 2.3E-38 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 152 235 4.8E-36 T 09-03-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 140 5.2E-34 T 09-03-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 SUPERFAMILY SSF69055 298 388 5.1E-29 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 SUPERFAMILY SSF55347 134 270 1.8E-53 T 09-03-2017 ARZXY2_RS11625 c5f81daeee7571c8448bf6168dc06383 394 Gene3D G3DSA:3.40.50.720 2 156 5.9E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 796 5.6E-61 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 14 797 0.0 T 09-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 PIRSF PIRSF000854 8 801 0.0 T 09-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 SUPERFAMILY SSF56059 11 392 5.42E-100 T 09-03-2017 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Gene3D G3DSA:3.30.1490.20 11 202 3.0E-64 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Gene3D G3DSA:3.30.470.20 204 365 1.5E-50 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 422 433 - T 09-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 SUPERFAMILY SSF52009 354 473 5.89E-32 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Gene3D G3DSA:3.20.20.60 488 799 3.9E-97 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 SUPERFAMILY SSF51621 469 800 4.97E-95 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Pfam PF00391 PEP-utilising enzyme, mobile domain 394 463 5.2E-25 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 27 348 1.2E-110 T 09-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 Gene3D G3DSA:3.50.30.10 384 481 1.7E-32 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09970 f079b37181d46dec20851fa0a9d1134f 802 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 703 721 - T 09-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 96 2.3E-15 T 09-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 261 2.0E-49 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 261 6.8E-42 T 09-03-2017 IPR000150 Cof protein GO:0016787 ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 Gene3D G3DSA:3.40.50.1000 1 72 2.1E-42 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 Gene3D G3DSA:3.40.50.1000 168 265 2.1E-42 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18285 b6df2c96fe13c2a44537f375d910477b 270 SUPERFAMILY SSF56784 1 263 5.02E-55 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS01985 31e52e3857d3982819dcf9d084445cfb 483 Pfam PF00171 Aldehyde dehydrogenase family 7 425 1.4E-40 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01985 31e52e3857d3982819dcf9d084445cfb 483 Gene3D G3DSA:3.40.605.10 7 234 6.9E-34 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01985 31e52e3857d3982819dcf9d084445cfb 483 Gene3D G3DSA:3.40.309.10 235 414 8.6E-49 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS01985 31e52e3857d3982819dcf9d084445cfb 483 SUPERFAMILY SSF53720 7 477 3.8E-78 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12435 b09c1fed9e89eab474560db4bffefd34 799 Gene3D G3DSA:3.90.260.10 497 591 4.6E-15 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS12435 b09c1fed9e89eab474560db4bffefd34 799 SUPERFAMILY SSF54001 525 591 1.23E-18 T 09-03-2017 ARZXY2_RS12435 b09c1fed9e89eab474560db4bffefd34 799 SMART SM00460 516 589 4.0E-9 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS12435 b09c1fed9e89eab474560db4bffefd34 799 Pfam PF01841 Transglutaminase-like superfamily 462 587 4.3E-21 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS04010 cee30d2e408986b31e59e1f4eadaad21 176 Pfam PF00582 Universal stress protein family 18 162 2.5E-15 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS04010 cee30d2e408986b31e59e1f4eadaad21 176 Gene3D G3DSA:3.40.50.620 12 165 1.7E-17 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS04010 cee30d2e408986b31e59e1f4eadaad21 176 SUPERFAMILY SSF52402 27 165 6.87E-18 T 09-03-2017 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Gene3D G3DSA:3.40.50.720 21 170 1.7E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 166 247 4.4E-19 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 SUPERFAMILY SSF55347 159 244 1.96E-29 T 09-03-2017 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 SUPERFAMILY SSF55347 298 358 1.96E-29 T 09-03-2017 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 26 154 8.4E-18 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 SUPERFAMILY SSF51735 21 185 2.88E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Gene3D G3DSA:3.30.360.10 299 359 8.4E-51 T 09-03-2017 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Gene3D G3DSA:3.30.360.10 401 456 8.4E-51 T 09-03-2017 ARZXY2_RS01965 17a17f1fcc630763b2c717912eac2bf8 469 Gene3D G3DSA:3.30.360.10 171 243 8.4E-51 T 09-03-2017 ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 Pfam PF01047 MarR family 69 110 4.6E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 2.4E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 2.4E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 2.4E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 Gene3D G3DSA:1.10.10.10 25 156 1.3E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 SUPERFAMILY SSF46785 26 157 2.51E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16060 92075c4fc938ded87c1b7fc859c26faf 169 SMART SM00347 41 144 6.5E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS06690 592fa0ff28266ff276a8314f75b41ac1 218 SMART SM00226 86 211 1.1E-41 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06690 592fa0ff28266ff276a8314f75b41ac1 218 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 88 208 6.7E-24 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06690 592fa0ff28266ff276a8314f75b41ac1 218 SUPERFAMILY SSF52788 87 209 4.06E-33 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06690 592fa0ff28266ff276a8314f75b41ac1 218 Gene3D G3DSA:3.40.50.270 86 209 2.4E-36 T 09-03-2017 ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 SUPERFAMILY SSF103473 24 442 6.8E-71 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 Pfam PF07690 Major Facilitator Superfamily 31 383 1.4E-29 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 307 324 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 Gene3D G3DSA:1.20.1250.20 24 227 1.8E-22 T 09-03-2017 ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 Gene3D G3DSA:1.20.1250.20 251 438 1.3E-22 T 09-03-2017 ARZXY2_RS00685 31c7d25e7169fb9bd6321e5a130ed54a 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.7E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 Gene3D G3DSA:3.40.50.720 3 245 1.2E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 184 0.0033 T 09-03-2017 ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.7E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.7E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.7E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 SUPERFAMILY SSF51735 3 245 1.45E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09565 a83d89d0717e5dc6a25a22fdb2158b96 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 3.1E-56 T 09-03-2017 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Gene3D G3DSA:2.30.42.10 473 560 2.8E-20 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 PRINTS PR00834 HtrA/DegQ protease family signature 417 434 7.1E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 PRINTS PR00834 HtrA/DegQ protease family signature 395 412 7.1E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 PRINTS PR00834 HtrA/DegQ protease family signature 507 519 7.1E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 PRINTS PR00834 HtrA/DegQ protease family signature 257 269 7.1E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 PRINTS PR00834 HtrA/DegQ protease family signature 283 303 7.1E-31 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 SUPERFAMILY SSF50156 451 558 2.5E-21 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Pfam PF13180 PDZ domain 471 558 6.5E-17 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 SMART SM00228 470 549 4.5E-13 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Gene3D G3DSA:2.40.10.10 243 324 1.8E-25 T 09-03-2017 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 SUPERFAMILY SSF50494 221 356 1.11E-51 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 SUPERFAMILY SSF50494 393 466 1.11E-51 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Gene3D G3DSA:2.40.10.10 325 358 8.6E-40 T 09-03-2017 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Gene3D G3DSA:2.40.10.10 395 472 8.6E-40 T 09-03-2017 ARZXY2_RS04605 0b6b85d34884112a305ecc86ab56bb39 562 Pfam PF13365 Trypsin-like peptidase domain 248 424 2.8E-31 T 09-03-2017 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 SMART SM01005 240 369 2.2E-45 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 Gene3D G3DSA:3.20.20.10 3 218 5.8E-65 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 Gene3D G3DSA:2.40.37.10 219 370 1.8E-47 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 TIGRFAM TIGR00492 alr: alanine racemase 1 368 4.6E-86 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 SUPERFAMILY SSF50621 233 370 8.37E-38 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 Pfam PF01168 Alanine racemase, N-terminal domain 1 226 3.4E-60 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 24 34 - T 09-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 351 364 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 119 131 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 294 311 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 19 35 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 273 288 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 55 73 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 199 226 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 PRINTS PR00992 Alanine racemase signature 156 167 8.7E-50 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 Hamap MF_01201 Alanine racemase. 1 369 28.042 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 SUPERFAMILY SSF51419 1 241 4.84E-57 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS13315 e679cbe47a722a86faab10aa18d2e583 390 Pfam PF00842 Alanine racemase, C-terminal domain 241 368 6.5E-31 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS01490 dbc4514252c05c941656992b8fa7be9f 275 Gene3D G3DSA:3.90.550.10 71 251 3.2E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01490 dbc4514252c05c941656992b8fa7be9f 275 Gene3D G3DSA:3.90.550.10 9 37 3.2E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01490 dbc4514252c05c941656992b8fa7be9f 275 SUPERFAMILY SSF53448 7 29 1.05E-27 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01490 dbc4514252c05c941656992b8fa7be9f 275 SUPERFAMILY SSF53448 62 264 1.05E-27 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01490 dbc4514252c05c941656992b8fa7be9f 275 Pfam PF00535 Glycosyl transferase family 2 11 177 9.1E-12 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS09955 fae71ba8208048ffec362326811f690e 85 Pfam PF02583 Metal-sensitive transcriptional repressor 11 80 3.1E-24 T 09-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 SMART SM00839 203 443 3.8E-79 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Gene3D G3DSA:1.10.285.10 370 444 3.0E-24 T 09-03-2017 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Gene3D G3DSA:1.10.285.10 5 65 3.1E-24 T 09-03-2017 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Gene3D G3DSA:3.40.192.10 66 186 2.9E-61 T 09-03-2017 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 SUPERFAMILY SSF51735 201 444 1.69E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 SUPERFAMILY SSF53223 5 195 3.84E-74 T 09-03-2017 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 443 6.2E-83 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 112 126 7.6E-30 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 369 380 7.6E-30 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 7.6E-30 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 7.6E-30 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 55 183 2.1E-49 T 09-03-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 Gene3D G3DSA:3.40.50.720 208 369 2.5E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01945 dea597a766e6449718af6478357fb19f 445 PIRSF PIRSF000185 19 445 8.3E-115 T 09-03-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 SUPERFAMILY SSF52402 23 159 2.43E-28 T 09-03-2017 ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 SUPERFAMILY SSF52402 191 327 1.05E-31 T 09-03-2017 ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 Gene3D G3DSA:3.40.50.620 21 159 7.7E-30 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 PRINTS PR01438 Universal stress protein signature 188 206 6.2E-15 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 PRINTS PR01438 Universal stress protein signature 285 297 6.2E-15 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 PRINTS PR01438 Universal stress protein signature 303 325 6.2E-15 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 Pfam PF00582 Universal stress protein family 190 325 9.6E-25 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 Pfam PF00582 Universal stress protein family 24 159 3.4E-20 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS16735 502dfba4ba4e9c6614e4edf0f3103cf3 345 Gene3D G3DSA:3.40.50.620 188 325 8.6E-35 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Pfam PF11941 Domain of unknown function (DUF3459) 501 584 4.4E-12 T 09-03-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Gene3D G3DSA:2.60.40.10 9 88 1.3E-21 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Gene3D G3DSA:3.20.20.80 104 438 2.8E-77 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Gene3D G3DSA:3.20.20.80 481 515 2.8E-77 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Pfam PF00128 Alpha amylase, catalytic domain 232 434 1.3E-5 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 Pfam PF00128 Alpha amylase, catalytic domain 121 213 7.0E-14 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 SUPERFAMILY SSF51445 88 518 2.32E-106 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 SUPERFAMILY SSF81296 7 88 8.2E-14 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 PIRSF PIRSF006337 2 587 8.0E-232 T 09-03-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 11 552 1.2E-227 T 09-03-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 ARZXY2_RS03780 c04ec64220ffbe6f933dffdd8e4866b7 588 SMART SM00642 88 457 3.8E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 188 200 3.8E-25 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 473 489 3.8E-25 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 517 531 3.8E-25 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 218 3.8E-25 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 6.2E-205 T 09-03-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Gene3D G3DSA:2.40.50.140 3 102 3.1E-35 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 562 34.882 T 09-03-2017 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 3.5E-15 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 SUPERFAMILY SSF50249 2 101 1.83E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 SUPERFAMILY SSF55261 286 408 1.8E-35 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Gene3D G3DSA:3.30.1360.30 274 402 8.5E-43 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Pfam PF02938 GAD domain 309 387 1.2E-14 T 09-03-2017 IPR029351 GAD domain Reactome: R-HSA-379726 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Gene3D G3DSA:3.30.930.10 133 273 8.5E-103 T 09-03-2017 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Gene3D G3DSA:3.30.930.10 403 583 8.5E-103 T 09-03-2017 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 556 2.4E-96 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 SUPERFAMILY SSF55681 116 308 1.06E-95 T 09-03-2017 ARZXY2_RS08025 257dd480e68c85b3b21223a85ea9f9f1 597 SUPERFAMILY SSF55681 395 556 1.06E-95 T 09-03-2017 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 36 263 2.5E-74 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 09-03-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 Pfam PF01255 Putative undecaprenyl diphosphate synthase 43 263 7.1E-75 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 Gene3D G3DSA:3.40.1180.10 32 265 4.6E-92 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 SUPERFAMILY SSF64005 36 259 1.11E-83 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS08340 c4bcad265e7ade66e4b483236dec2ece 273 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 36 264 37.938 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 13 467 32.353 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Gene3D G3DSA:1.10.8.60 298 366 3.6E-28 T 09-03-2017 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 SMART SM00382 164 292 9.7E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 ProSitePatterns PS01008 DnaA protein signature. 426 445 - T 09-03-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 378 445 1.3E-30 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 SMART SM00760 376 445 2.6E-39 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Pfam PF00308 Bacterial dnaA protein 132 349 1.3E-97 T 09-03-2017 IPR013317 Chromosomal replication initiator protein DnaA ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 426 445 1.2E-52 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 263 290 1.2E-52 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 197 211 1.2E-52 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 229 243 1.2E-52 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 165 185 1.2E-52 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Gene3D G3DSA:1.10.1750.10 367 468 2.7E-40 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 Gene3D G3DSA:3.40.50.300 131 296 4.0E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 17 466 5.6E-161 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 SUPERFAMILY SSF52540 132 343 1.3E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18570 8e78555584d937e9fb16dc0d5af2b0cf 473 SUPERFAMILY SSF48295 363 468 7.32E-36 T 09-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 16 699 0.0 T 09-03-2017 IPR011966 Phenylacetic acid degradation protein PaaN ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 Gene3D G3DSA:3.40.309.10 282 475 2.6E-37 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 Gene3D G3DSA:3.10.129.10 553 698 6.1E-38 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 Gene3D G3DSA:3.40.605.10 15 281 9.7E-32 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 SUPERFAMILY SSF53720 12 523 4.84E-74 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 Pfam PF01575 MaoC like domain 571 667 2.1E-18 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 SUPERFAMILY SSF54637 555 698 8.89E-31 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02305 1e52d82e7c1af6663e6e6c309d8406dc 699 Pfam PF00171 Aldehyde dehydrogenase family 25 510 4.6E-56 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 PRINTS PR00625 DnaJ domain signature 12 30 2.6E-20 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 PRINTS PR00625 DnaJ domain signature 30 45 2.6E-20 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 PRINTS PR00625 DnaJ domain signature 47 67 2.6E-20 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 SUPERFAMILY SSF49493 142 218 6.93E-17 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 SMART SM00271 9 67 1.2E-28 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 SUPERFAMILY SSF46565 9 113 4.32E-30 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 Pfam PF00226 DnaJ domain 10 72 1.3E-26 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 SUPERFAMILY SSF49493 216 299 2.62E-22 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 Gene3D G3DSA:1.10.287.110 4 108 2.1E-31 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 Gene3D G3DSA:2.60.260.20 214 291 4.8E-22 T 09-03-2017 ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 Gene3D G3DSA:2.60.260.20 141 212 2.5E-15 T 09-03-2017 ARZXY2_RS00730 328ef3faf20d4fe04cf621741ab90c87 323 Pfam PF01556 DnaJ C terminal domain 151 290 2.0E-34 T 09-03-2017 IPR002939 Chaperone DnaJ, C-terminal ARZXY2_RS02310 967f31a510a6ad924911c5fae77c0589 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 89 1.4E-4 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS02310 967f31a510a6ad924911c5fae77c0589 135 Gene3D G3DSA:3.10.180.10 10 130 1.1E-15 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS02310 967f31a510a6ad924911c5fae77c0589 135 SUPERFAMILY SSF54593 10 128 1.34E-15 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 Gene3D G3DSA:1.20.120.530 83 222 8.7E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 3.5E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 SUPERFAMILY SSF46785 13 83 2.46E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 SUPERFAMILY SSF48008 86 222 4.97E-21 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 Pfam PF07729 FCD domain 90 212 2.0E-18 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 Gene3D G3DSA:1.10.10.10 10 78 1.5E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 SMART SM00345 21 79 1.6E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20370 c062971ee253ad634418c9250c75088a 223 SMART SM00895 89 214 2.7E-16 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 SUPERFAMILY SSF51735 6 256 1.41E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.3E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.3E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.3E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.3E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 255 6.8E-58 T 09-03-2017 ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 Gene3D G3DSA:3.40.50.720 4 256 5.2E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 8.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 8.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18875 6408a804ae0ed6befff2d5ea2da2a71d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 8.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 Pfam PF00072 Response regulator receiver domain 11 119 5.3E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 SUPERFAMILY SSF52172 7 131 1.42E-36 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 SMART SM00331 159 366 5.9E-26 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 SUPERFAMILY SSF81606 171 366 2.09E-12 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 Gene3D G3DSA:3.40.50.2300 10 140 2.8E-35 T 09-03-2017 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 185 366 5.9E-36 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 SMART SM00448 8 118 1.1E-35 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS01205 e5a4f21b4a42eeb697bac54d286aefdf 375 Gene3D G3DSA:3.60.40.10 294 365 8.2E-8 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS05565 680ce2761a8f299957b11b5274212f0b 374 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 355 1.9E-210 T 09-03-2017 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative ARZXY2_RS05565 680ce2761a8f299957b11b5274212f0b 374 SUPERFAMILY SSF51679 1 333 6.95E-71 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS05565 680ce2761a8f299957b11b5274212f0b 374 Pfam PF00296 Luciferase-like monooxygenase 1 294 1.1E-55 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS05565 680ce2761a8f299957b11b5274212f0b 374 Gene3D G3DSA:3.20.20.30 1 336 7.9E-79 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS14035 7dd4ec8edc8d6409d9ee323c5a35d2fa 304 SMART SM00382 51 244 3.8E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14035 7dd4ec8edc8d6409d9ee323c5a35d2fa 304 SUPERFAMILY SSF52540 26 254 1.47E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14035 7dd4ec8edc8d6409d9ee323c5a35d2fa 304 Gene3D G3DSA:3.40.50.300 26 261 1.9E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14035 7dd4ec8edc8d6409d9ee323c5a35d2fa 304 Pfam PF00005 ABC transporter 42 196 9.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14035 7dd4ec8edc8d6409d9ee323c5a35d2fa 304 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Gene3D G3DSA:3.40.50.300 17 207 7.4E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Pfam PF00009 Elongation factor Tu GTP binding domain 19 195 1.8E-52 T 09-03-2017 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Hamap MF_00071 Elongation factor 4 [lepA]. 1 611 279.874 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Gene3D G3DSA:3.30.70.870 306 382 1.6E-23 T 09-03-2017 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Gene3D G3DSA:2.40.30.10 208 302 3.5E-20 T 09-03-2017 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Pfam PF06421 GTP-binding protein LepA C-terminus 502 606 8.5E-48 T 09-03-2017 IPR013842 GTP-binding protein LepA, C-terminal ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 SUPERFAMILY SSF50447 196 299 1.14E-17 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Pfam PF00679 Elongation factor G C-terminus 412 498 2.4E-20 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 SUPERFAMILY SSF54980 306 384 2.48E-18 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 Gene3D G3DSA:3.30.70.240 414 503 3.1E-20 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 SUPERFAMILY SSF52540 14 220 4.82E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 PRINTS PR00315 GTP-binding elongation factor signature 64 72 5.8E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 PRINTS PR00315 GTP-binding elongation factor signature 88 98 5.8E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 PRINTS PR00315 GTP-binding elongation factor signature 104 115 5.8E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 PRINTS PR00315 GTP-binding elongation factor signature 140 149 5.8E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 PRINTS PR00315 GTP-binding elongation factor signature 21 34 5.8E-14 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 SUPERFAMILY SSF54980 412 507 1.49E-23 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 SMART SM00838 414 499 4.6E-4 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 TIGRFAM TIGR01393 lepA: elongation factor 4 19 608 1.9E-288 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 ARZXY2_RS08255 fa766320f283dad0edd766152ad93d36 617 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 190 5.7E-21 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 Pfam PF00106 short chain dehydrogenase 18 211 2.0E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 Gene3D G3DSA:3.40.50.720 11 251 1.3E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 8.8E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 8.8E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 8.8E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12475 592870393f6210ced34f4f95414763d6 288 SUPERFAMILY SSF51735 12 244 8.96E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04840 e0ac546f9fcfb3cd20892bccae139055 205 SUPERFAMILY SSF51161 9 170 2.09E-39 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS04840 e0ac546f9fcfb3cd20892bccae139055 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 151 7.4E-5 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS04840 e0ac546f9fcfb3cd20892bccae139055 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 23 56 6.6E-8 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS04840 e0ac546f9fcfb3cd20892bccae139055 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 58 93 5.8E-5 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS04840 e0ac546f9fcfb3cd20892bccae139055 205 Gene3D G3DSA:2.160.10.10 21 181 6.2E-36 T 09-03-2017 ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 SMART SM00967 81 157 3.3E-16 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 Gene3D G3DSA:3.40.1280.10 177 328 3.4E-46 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 SUPERFAMILY SSF55315 76 154 1.88E-15 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 Gene3D G3DSA:3.30.1330.30 74 153 7.3E-19 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 81 156 5.8E-16 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 Pfam PF00588 SpoU rRNA Methylase family 180 321 1.3E-34 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 SUPERFAMILY SSF75217 145 328 3.14E-42 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS14875 c5c98cafb34f021217b28fc55140c34a 330 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 80 327 2.9E-60 T 09-03-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 ARZXY2_RS09055 c59c123d477e946b4efffeae33da59a0 256 Gene3D G3DSA:3.40.50.1360 3 244 2.2E-69 T 09-03-2017 ARZXY2_RS09055 c59c123d477e946b4efffeae33da59a0 256 SUPERFAMILY SSF100950 3 245 4.95E-59 T 09-03-2017 ARZXY2_RS09055 c59c123d477e946b4efffeae33da59a0 256 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 2 234 7.7E-72 T 09-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 ARZXY2_RS09055 c59c123d477e946b4efffeae33da59a0 256 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 3 243 7.1E-65 T 09-03-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 ARZXY2_RS06365 68786078c211496d88ce1ab669078c0a 162 Pfam PF10686 Protein of unknown function (DUF2493) 10 76 1.0E-10 T 09-03-2017 IPR019627 Mycobacteriophage D29, Gp61 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 12 208 39.744 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 Gene3D G3DSA:3.30.230.40 12 99 2.3E-34 T 09-03-2017 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 Gene3D G3DSA:3.30.230.40 100 208 9.0E-30 T 09-03-2017 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 170 182 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 41 188 1.3E-56 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 SUPERFAMILY SSF54211 12 95 1.39E-30 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 71 84 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 ARZXY2_RS11330 124d5470d0744e38dcc77faf1c39eb1c 208 SUPERFAMILY SSF54211 97 193 2.15E-28 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 SUPERFAMILY SSF53167 12 271 3.34E-76 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 32 270 1.7E-71 T 09-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 32 270 2.4E-98 T 09-03-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 PIRSF PIRSF000477 4 272 5.7E-85 T 09-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 Pfam PF01048 Phosphorylase superfamily 32 270 3.2E-39 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ARZXY2_RS12555 4f6aa1b66a94aa92fab0c4d748896bb4 272 Gene3D G3DSA:3.40.50.1580 9 272 3.6E-87 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 6 350 56.452 T 09-03-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 SUPERFAMILY SSF53659 6 350 1.42E-109 T 09-03-2017 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 245 264 - T 09-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 Gene3D G3DSA:3.40.718.10 6 340 5.6E-112 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 8 332 7.3E-93 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS05680 3d5f3fb9b2b2e5948676266e71a483e4 350 SMART SM01329 7 346 5.5E-163 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS09505 90d6c9b83ac84f5b29b63e80ad6ec9b6 255 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 8 255 4.7E-107 T 09-03-2017 IPR022292 Conserved hypothetical protein CHP03843 ARZXY2_RS18250 50d8f888855d5bc38097b149ba62b6a7 237 SMART SM00849 7 216 3.0E-28 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS18250 50d8f888855d5bc38097b149ba62b6a7 237 Gene3D G3DSA:3.60.15.10 8 227 1.4E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS18250 50d8f888855d5bc38097b149ba62b6a7 237 SUPERFAMILY SSF56281 7 230 1.78E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS18250 50d8f888855d5bc38097b149ba62b6a7 237 Pfam PF00753 Metallo-beta-lactamase superfamily 7 216 2.3E-30 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 Gene3D G3DSA:3.40.190.10 270 308 8.0E-21 T 09-03-2017 ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 Gene3D G3DSA:3.40.190.10 75 155 8.0E-21 T 09-03-2017 ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 79 307 4.6E-37 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 SUPERFAMILY SSF53850 68 308 2.65E-43 T 09-03-2017 ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 Gene3D G3DSA:3.40.190.10 156 267 5.3E-28 T 09-03-2017 ARZXY2_RS00160 0bfdae757e9155386b5d795c0a826107 326 SMART SM00062 78 310 2.4E-25 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS00425 064c3e3ad8876f2ddd0ffd5b59aed5be 242 Pfam PF04954 Siderophore-interacting protein 120 241 5.9E-21 T 09-03-2017 IPR007037 Siderophore-interacting protein ARZXY2_RS00425 064c3e3ad8876f2ddd0ffd5b59aed5be 242 Pfam PF08021 Siderophore-interacting FAD-binding domain 52 106 3.4E-7 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting ARZXY2_RS00425 064c3e3ad8876f2ddd0ffd5b59aed5be 242 Gene3D G3DSA:3.40.50.80 116 241 3.8E-26 T 09-03-2017 ARZXY2_RS00425 064c3e3ad8876f2ddd0ffd5b59aed5be 242 Gene3D G3DSA:2.40.30.10 15 109 1.1E-17 T 09-03-2017 ARZXY2_RS00425 064c3e3ad8876f2ddd0ffd5b59aed5be 242 SUPERFAMILY SSF63380 11 107 2.21E-9 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 24 1132 12.3 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF04561 RNA polymerase Rpb2, domain 2 171 373 1.8E-26 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 09-03-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:2.40.50.100 637 707 6.8E-24 T 09-03-2017 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:2.40.270.10 708 735 1.8E-76 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:2.40.270.10 875 1032 1.8E-76 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 237 852 2.5E-304 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:2.30.150.10 511 578 5.2E-26 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 SUPERFAMILY SSF64484 23 1141 0.0 T 09-03-2017 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF04563 RNA polymerase beta subunit 82 417 4.3E-23 T 09-03-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:3.90.1100.10 362 510 2.6E-147 T 09-03-2017 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:3.90.1100.10 581 635 2.6E-147 T 09-03-2017 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:3.90.1100.10 31 171 2.6E-147 T 09-03-2017 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:2.40.50.150 744 874 2.0E-55 T 09-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF04560 RNA polymerase Rpb2, domain 7 1056 1130 1.8E-27 T 09-03-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Gene3D G3DSA:3.90.1110.10 173 345 1.4E-64 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF10385 RNA polymerase beta subunit external 1 domain 510 578 4.0E-24 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF00562 RNA polymerase Rpb2, domain 6 639 1054 3.0E-157 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03450 1f2cb950543658813c2f815711aadd4a 1168 Pfam PF04565 RNA polymerase Rpb2, domain 3 432 500 6.8E-28 T 09-03-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 SUPERFAMILY SSF51905 262 373 2.82E-69 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 SUPERFAMILY SSF51905 5 175 2.82E-69 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 Pfam PF01494 FAD binding domain 6 339 2.5E-80 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 Gene3D G3DSA:3.50.50.60 263 347 1.4E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 Gene3D G3DSA:3.50.50.60 4 180 1.4E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.3E-38 T 09-03-2017 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 4.3E-38 T 09-03-2017 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 4.3E-38 T 09-03-2017 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 326 4.3E-38 T 09-03-2017 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 4.3E-38 T 09-03-2017 ARZXY2_RS19100 2e12232d590f06df34d42b93d2e512e1 547 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 4.3E-38 T 09-03-2017 ARZXY2_RS05365 6fa84da0118c15ea415c2cc698f3903d 120 Gene3D G3DSA:3.30.1390.10 15 105 5.7E-27 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ARZXY2_RS05365 6fa84da0118c15ea415c2cc698f3903d 120 SUPERFAMILY SSF54736 29 103 5.23E-23 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ARZXY2_RS05365 6fa84da0118c15ea415c2cc698f3903d 120 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 32 100 7.8E-20 T 09-03-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 ARZXY2_RS05365 6fa84da0118c15ea415c2cc698f3903d 120 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 13 106 15.47 T 09-03-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 Gene3D G3DSA:3.40.50.1820 20 260 1.2E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 SUPERFAMILY SSF53474 20 260 4.39E-43 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 2.6E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.6E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 2.6E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 2.6E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17455 d93caf87323661e3205392144007502c 267 Pfam PF12697 Alpha/beta hydrolase family 27 252 2.9E-23 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17960 99c39f80296ff1ade2a1fc2883ecba62 513 Pfam PF03703 Bacterial PH domain 83 162 3.2E-17 T 09-03-2017 IPR005182 Domain of unknown function DUF304 ARZXY2_RS17960 99c39f80296ff1ade2a1fc2883ecba62 513 Pfam PF03703 Bacterial PH domain 381 456 3.5E-11 T 09-03-2017 IPR005182 Domain of unknown function DUF304 ARZXY2_RS17960 99c39f80296ff1ade2a1fc2883ecba62 513 Pfam PF03703 Bacterial PH domain 250 308 7.1E-9 T 09-03-2017 IPR005182 Domain of unknown function DUF304 ARZXY2_RS17960 99c39f80296ff1ade2a1fc2883ecba62 513 PIRSF PIRSF026631 14 471 5.0E-86 T 09-03-2017 IPR014529 Uncharacterised conserved protein UCP026631 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PIRSF PIRSF000530 1 386 2.1E-117 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 Pfam PF00288 GHMP kinases N terminal domain 117 183 9.9E-14 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 Gene3D G3DSA:3.30.230.10 10 212 2.8E-69 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 ProSitePatterns PS00106 Galactokinase signature. 30 41 - T 09-03-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 TIGRFAM TIGR00131 gal_kin: galactokinase 11 366 9.2E-95 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 Pfam PF08544 GHMP kinases C terminal 286 368 2.3E-11 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 SUPERFAMILY SSF55060 209 384 3.96E-48 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 Gene3D G3DSA:3.30.70.890 213 383 6.3E-55 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 SUPERFAMILY SSF54211 8 205 4.93E-59 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 Pfam PF10509 Galactokinase galactose-binding signature 13 60 1.0E-21 T 09-03-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00473 Galactokinase signature 114 132 7.5E-25 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00473 Galactokinase signature 30 48 7.5E-25 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00473 Galactokinase signature 268 282 7.5E-25 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00473 Galactokinase signature 94 105 7.5E-25 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00959 Mevalonate kinase family signature 164 183 1.3E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00959 Mevalonate kinase family signature 331 348 1.3E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00959 Mevalonate kinase family signature 121 143 1.3E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS13045 63599a81d111c2d85c7cc62fb642fe8b 386 PRINTS PR00959 Mevalonate kinase family signature 28 52 1.3E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 SMART SM00857 5 146 4.3E-19 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 Pfam PF13408 Recombinase zinc beta ribbon domain 266 319 2.6E-8 T 09-03-2017 IPR025827 Recombinase zinc beta ribbon domain ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 Pfam PF00239 Resolvase, N terminal domain 5 97 7.8E-15 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 SUPERFAMILY SSF53041 4 145 1.03E-16 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 Gene3D G3DSA:3.40.50.1390 4 97 4.5E-13 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS07120 5afab44c0a2786752edd7dacf27af00c 480 Pfam PF07508 Recombinase 167 253 1.6E-11 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 SUPERFAMILY SSF52540 196 443 5.19E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 Gene3D G3DSA:1.10.860.10 21 123 4.2E-40 T 09-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 Pfam PF00772 DnaB-like helicase N terminal domain 21 122 2.8E-35 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 21 452 1.7E-169 T 09-03-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 SUPERFAMILY SSF48024 19 130 2.48E-37 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 Pfam PF03796 DnaB-like helicase C terminal domain 196 450 1.5E-108 T 09-03-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS18850 831d4ba3cba7219cd9f7f67b0908710e 461 Gene3D G3DSA:3.40.50.300 180 452 2.3E-115 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 Pfam PF08031 Berberine and berberine like 405 439 6.1E-10 T 09-03-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 Pfam PF01565 FAD binding domain 26 160 1.7E-34 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 Gene3D G3DSA:3.30.465.10 84 191 7.6E-17 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 Gene3D G3DSA:3.30.43.10 17 83 8.5E-12 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 26 59 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 ARZXY2_RS01060 796ed57e80cb9b224d6695a6a304ea60 444 SUPERFAMILY SSF56176 3 191 1.68E-55 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 SMART SM00387 426 548 3.5E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Gene3D G3DSA:1.10.287.130 317 375 7.7E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Gene3D G3DSA:3.30.565.10 396 545 4.9E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 1.5E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 484 1.5E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 545 1.5E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 SUPERFAMILY SSF55785 234 331 5.08E-5 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 SUPERFAMILY SSF55890 337 385 1.18E-9 T 09-03-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 SUPERFAMILY SSF103190 32 176 7.46E-26 T 09-03-2017 IPR029151 Periplasmic sensor domain-like ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 330 375 8.9E-12 T 09-03-2017 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Gene3D G3DSA:3.30.450.20 31 178 1.2E-37 T 09-03-2017 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Pfam PF17203 Single cache domain 3 33 178 2.7E-18 T 09-03-2017 IPR033463 Single cache domain 3 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 SUPERFAMILY SSF55874 395 545 1.06E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Gene3D G3DSA:3.30.450.20 227 259 8.7E-5 T 09-03-2017 ARZXY2_RS12365 376e649573b65a7e5b31ab15c91f80c2 575 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 544 4.2E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 523 559 0.002 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 286 8.8E-4 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 SUPERFAMILY SSF52540 299 543 1.82E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Gene3D G3DSA:3.40.50.300 11 278 3.0E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Gene3D G3DSA:3.40.50.300 297 544 1.1E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Pfam PF00005 ABC transporter 321 472 2.3E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 Pfam PF00005 ABC transporter 38 199 1.9E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 SMART SM00382 47 249 1.8E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 SMART SM00382 329 517 3.1E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04705 f782f2928f1e5fd3bc6b8218fba7bca8 572 SUPERFAMILY SSF52540 18 271 3.99E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 Pfam PF13185 GAF domain 34 163 2.9E-7 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 SUPERFAMILY SSF55781 32 169 1.3E-15 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 SMART SM00065 26 173 1.1E-4 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 Gene3D G3DSA:3.30.450.40 5 170 2.2E-15 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 Gene3D G3DSA:1.10.10.10 178 232 1.1E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 PIRSF PIRSF036625 2 242 4.8E-40 T 09-03-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 SMART SM01012 175 230 3.2E-19 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS16050 500d0411017279f903646c95f4754b13 246 Pfam PF03861 ANTAR domain 178 229 2.1E-16 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 SUPERFAMILY SSF102588 37 254 9.55E-37 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 Gene3D G3DSA:3.40.50.150 263 426 2.1E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 SUPERFAMILY SSF53335 268 410 4.48E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 Pfam PF05401 Nodulation protein S (NodS) 278 405 1.6E-13 T 09-03-2017 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 Pfam PF02585 GlcNAc-PI de-N-acetylase 41 169 9.6E-19 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS01495 62e3a9004a72cf1f449411dc14d8b46c 454 Gene3D G3DSA:3.40.50.10320 37 260 5.8E-36 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 SMART SM00861 30 194 1.0E-49 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 SUPERFAMILY SSF52922 200 335 3.14E-31 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 Gene3D G3DSA:3.40.50.970 25 206 1.4E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 Pfam PF02779 Transketolase, pyrimidine binding domain 31 193 3.7E-33 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 SUPERFAMILY SSF52518 24 195 6.38E-48 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 Pfam PF02780 Transketolase, C-terminal domain 206 327 7.0E-25 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS18895 ecdb0e09bc8c25053b2177b73e9e079b 336 Gene3D G3DSA:3.40.50.920 207 333 1.1E-31 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS07540 b5220617480e5c29077c31b66a098fc2 231 Pfam PF00924 Mechanosensitive ion channel 88 194 9.0E-29 T 09-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 ARZXY2_RS07540 b5220617480e5c29077c31b66a098fc2 231 Gene3D G3DSA:2.30.30.60 145 187 4.0E-10 T 09-03-2017 ARZXY2_RS07540 b5220617480e5c29077c31b66a098fc2 231 SUPERFAMILY SSF82861 68 128 1.83E-11 T 09-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 ARZXY2_RS07540 b5220617480e5c29077c31b66a098fc2 231 SUPERFAMILY SSF50182 130 187 2.84E-11 T 09-03-2017 IPR010920 LSM domain ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 Gene3D G3DSA:1.20.1250.20 260 471 6.8E-15 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 Gene3D G3DSA:1.20.1250.20 15 183 3.0E-27 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.2E-6 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 2.2E-6 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 201 219 2.2E-6 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 2.2E-6 T 09-03-2017 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 Pfam PF07690 Major Facilitator Superfamily 19 408 3.1E-49 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 SUPERFAMILY SSF103473 11 195 5.23E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS07280 d89b3db25baab778b8ef7f1ae5290693 477 SUPERFAMILY SSF103473 246 461 5.23E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 PIRSF PIRSF000545 5 321 1.3E-135 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 15 320 2.4E-120 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 94 237 2.4E-11 T 09-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 Gene3D G3DSA:3.40.50.300 14 320 5.9E-103 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 SUPERFAMILY SSF52540 14 320 1.01E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03750 9aa223b56b6fcd905841da9a70165c93 321 Hamap MF_00215 Pantothenate kinase [coaA]. 1 321 167.498 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 Gene3D G3DSA:3.40.50.150 322 535 1.4E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 441 465 2.3E-8 T 09-03-2017 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 335 2.3E-8 T 09-03-2017 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 425 437 2.3E-8 T 09-03-2017 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 343 357 2.3E-8 T 09-03-2017 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 Pfam PF02384 N-6 DNA Methylase 297 523 1.1E-24 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04160 9fd1887b6ffc9a2979cac0dd7461fabc 620 SUPERFAMILY SSF53335 269 566 3.38E-57 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SUPERFAMILY SSF53098 335 486 4.32E-48 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Pfam PF16921 Tex protein YqgF-like domain 340 468 7.0E-50 T 09-03-2017 IPR032639 Tex protein, YqgF-like domain ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:1.10.10.650 11 119 4.4E-44 T 09-03-2017 IPR023319 Tex-like protein, HTH domain ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:1.10.150.310 516 638 2.5E-40 T 09-03-2017 IPR023097 Tex RuvX-like domain ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:2.40.50.140 647 728 1.2E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SMART SM00732 339 441 1.3E-33 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SMART SM00316 657 728 2.0E-25 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:1.10.3500.10 468 515 1.3E-93 T 09-03-2017 IPR023323 Tex-like domain ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:1.10.3500.10 120 335 1.3E-93 T 09-03-2017 IPR023323 Tex-like domain ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SUPERFAMILY SSF158832 14 334 3.66E-106 T 09-03-2017 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Pfam PF00575 S1 RNA binding domain 657 728 6.3E-19 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Pfam PF12836 Helix-hairpin-helix motif 508 572 5.0E-28 T 09-03-2017 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Gene3D G3DSA:3.30.420.140 339 467 2.4E-48 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SUPERFAMILY SSF47781 487 574 4.11E-27 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SUPERFAMILY SSF47781 578 639 4.0E-14 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 Pfam PF09371 Tex-like protein N-terminal domain 19 203 1.6E-68 T 09-03-2017 IPR018974 Tex-like protein, N-terminal ARZXY2_RS13760 5fed4a00aff055866f343388ceb974c8 805 SUPERFAMILY SSF50249 645 730 1.49E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PIRSF PIRSF000109 1 474 7.9E-201 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 355 377 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.4E-79 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 Gene3D G3DSA:3.40.50.720 2 179 2.0E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 172 5.6E-50 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 SUPERFAMILY SSF48179 176 469 3.13E-114 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 466 4.7E-204 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 Gene3D G3DSA:1.20.5.320 435 475 4.2E-17 T 09-03-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 465 3.8E-120 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 Gene3D G3DSA:1.10.1040.10 180 432 7.9E-104 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 SUPERFAMILY SSF51735 3 176 8.25E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 09-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS07420 22bbc96d4f58089622e851cc94476450 478 SMART SM01350 178 466 1.4E-193 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 Pfam PF00171 Aldehyde dehydrogenase family 20 470 4.3E-151 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 Gene3D G3DSA:3.40.309.10 262 450 1.4E-60 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 Gene3D G3DSA:3.40.605.10 3 261 1.7E-85 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02945 d15b695cf2e2592157a6a0a8f014ff92 476 SUPERFAMILY SSF53720 3 471 7.33E-149 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 6.7E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 6.7E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 6.7E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 6.7E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 09-03-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 12 73 2.2E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 Gene3D G3DSA:4.10.640.10 12 74 3.2E-28 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 SUPERFAMILY SSF46911 6 74 3.01E-25 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 75 6.0E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 19.843 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18790 ddf7f08a623987c841fbef3a8b5d480e 79 Pfam PF01084 Ribosomal protein S18 22 71 4.1E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 18 27 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Hamap MF_01228 Methionine--tRNA ligase [metG]. 4 513 46.229 T 09-03-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 484 6.7E-160 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Gene3D G3DSA:2.170.220.10 120 232 2.6E-44 T 09-03-2017 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 43 57 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 231 242 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 356 367 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 264 279 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 91 102 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 11 24 1.4E-34 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 SUPERFAMILY SSF47323 357 512 4.67E-42 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Pfam PF09334 tRNA synthetases class I (M) 9 368 8.5E-113 T 09-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 SUPERFAMILY SSF52374 6 359 9.92E-115 T 09-03-2017 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Pfam PF08264 Anticodon-binding domain of tRNA 390 482 6.3E-6 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Gene3D G3DSA:3.40.50.620 6 117 1.3E-79 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Gene3D G3DSA:3.40.50.620 233 342 1.3E-79 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05655 09d7f63bc37c3ce731755f348f87924a 519 Gene3D G3DSA:1.10.730.10 346 512 2.8E-55 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS19320 77dcff7275250690629bedd0bc23241d 515 Pfam PF04986 Putative transposase 174 367 5.2E-52 T 09-03-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS19320 77dcff7275250690629bedd0bc23241d 515 Pfam PF14319 Transposase zinc-binding domain 47 139 1.6E-21 T 09-03-2017 IPR026889 Transposase zinc-binding domain ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 103 2.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 2.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 34 2.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 3 110 8.9E-14 T 09-03-2017 ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 SUPERFAMILY SSF51735 1 110 3.42E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS22820 575b9551a158eac0856416b4467516f6 110 Gene3D G3DSA:3.40.50.720 1 110 1.7E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09760 f3a3f78f4433442dc739b1cd5f30118e 299 Gene3D G3DSA:3.90.850.10 82 296 5.3E-79 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09760 f3a3f78f4433442dc739b1cd5f30118e 299 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 294 5.9E-66 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09760 f3a3f78f4433442dc739b1cd5f30118e 299 SUPERFAMILY SSF56529 78 294 3.01E-75 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS10145 0a468a58a4811fb390eb826c467e5c5e 290 SUPERFAMILY SSF49299 8 54 9.68E-5 T 09-03-2017 IPR000601 PKD domain ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 PRINTS PR00315 GTP-binding elongation factor signature 456 469 7.9E-10 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 PRINTS PR00315 GTP-binding elongation factor signature 508 518 7.9E-10 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 PRINTS PR00315 GTP-binding elongation factor signature 560 569 7.9E-10 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 PRINTS PR00315 GTP-binding elongation factor signature 524 535 7.9E-10 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Gene3D G3DSA:2.40.30.10 628 722 2.9E-21 T 09-03-2017 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 SUPERFAMILY SSF52156 737 867 4.97E-34 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Pfam PF00009 Elongation factor Tu GTP binding domain 457 616 8.3E-33 T 09-03-2017 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 959 16.813 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Gene3D G3DSA:3.40.50.10050 758 838 1.1E-20 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Gene3D G3DSA:2.40.30.10 862 959 4.2E-31 T 09-03-2017 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 SUPERFAMILY SSF50447 861 959 1.26E-25 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Gene3D G3DSA:3.40.50.300 453 616 1.3E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 370 417 5.1E-8 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 1.0E-13 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 456 615 2.7E-30 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 SUPERFAMILY SSF50447 629 712 2.91E-24 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 366 958 1.5E-227 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 SUPERFAMILY SSF52540 450 619 8.33E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 ProSitePatterns PS01176 Initiation factor 2 signature. 912 934 - T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11550 1ce302358fb388caeaff47a6f54dd977 960 Pfam PF11987 Translation-initiation factor 2 744 850 1.7E-32 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Gene3D G3DSA:3.40.50.970 3 189 1.2E-46 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Gene3D G3DSA:3.40.50.970 244 312 1.2E-46 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Gene3D G3DSA:3.40.50.920 512 628 2.8E-23 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 631 9.1E-176 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Pfam PF02779 Transketolase, pyrimidine binding domain 325 487 1.9E-37 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 SUPERFAMILY SSF52922 512 629 2.75E-19 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 SUPERFAMILY SSF52518 247 371 1.75E-65 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 SUPERFAMILY SSF52518 21 195 1.75E-65 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Gene3D G3DSA:3.40.50.970 313 488 5.5E-52 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 SMART SM00861 324 488 1.6E-48 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Pfam PF02780 Transketolase, C-terminal domain 512 624 1.4E-22 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 633 39.005 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 SUPERFAMILY SSF52518 302 486 1.21E-50 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 ProSitePatterns PS00802 Transketolase signature 2. 430 446 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 287 8.0E-101 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS10510 0e0cdf7490033405acbf18c5f9aab29b 657 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 Gene3D G3DSA:3.30.200.20 16 82 2.1E-17 T 09-03-2017 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 Pfam PF00069 Protein kinase domain 18 267 3.2E-41 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 Gene3D G3DSA:1.10.510.10 83 267 3.5E-39 T 09-03-2017 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 SMART SM00220 16 275 3.2E-49 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 SUPERFAMILY SSF56112 14 363 8.63E-63 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS12415 1a7a1b934ce5a423e3e5620ef76ccb89 573 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 ARZXY2_RS10835 0fff013196192026a0a8938b896b205d 323 Pfam PF03799 Cell division protein FtsQ 197 300 8.1E-8 T 09-03-2017 IPR005548 Cell division protein FtsQ/DivIB ARZXY2_RS10835 0fff013196192026a0a8938b896b205d 323 Pfam PF08478 POTRA domain, FtsQ-type 126 193 2.3E-9 T 09-03-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type ARZXY2_RS15505 3ee2ff973acfc7b50c3fdedbf795e451 179 Gene3D G3DSA:3.90.79.10 57 153 7.3E-5 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS15505 3ee2ff973acfc7b50c3fdedbf795e451 179 Pfam PF16262 Domain of unknown function (DUF4916) 9 176 4.0E-79 T 09-03-2017 IPR032582 Protein of unknown function DUF4916 ARZXY2_RS15505 3ee2ff973acfc7b50c3fdedbf795e451 179 SUPERFAMILY SSF55811 49 154 1.12E-5 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 SUPERFAMILY SSF50677 224 449 9.94E-38 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Pfam PF08264 Anticodon-binding domain of tRNA 753 891 4.5E-20 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Gene3D G3DSA:3.40.50.620 19 214 1.4E-142 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Gene3D G3DSA:3.40.50.620 452 694 1.4E-142 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 30 697 4.0E-167 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 15 1093 13.658 T 09-03-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 79 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 582 595 1.3E-22 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 622 631 1.3E-22 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 252 275 1.3E-22 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 61 72 1.3E-22 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 SUPERFAMILY SSF52374 21 218 1.74E-126 T 09-03-2017 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 SUPERFAMILY SSF52374 449 696 1.74E-126 T 09-03-2017 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 18 898 9.1E-244 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Gene3D G3DSA:3.90.740.10 225 435 4.8E-46 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 Gene3D G3DSA:1.10.730.10 705 884 2.1E-38 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07635 76462fdc518669f45be2c32bd0c51a9c 1099 SUPERFAMILY SSF47323 717 955 1.4E-37 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 Gene3D G3DSA:3.40.50.720 5 254 9.0E-83 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 SUPERFAMILY SSF51735 5 254 1.39E-78 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 7.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 7.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 7.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07405 79b0483b7f077406ee0ae995ac21420b 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 1.8E-58 T 09-03-2017 ARZXY2_RS19010 6e578d11454dc582232ab25539833d75 164 Pfam PF14031 Putative serine dehydratase domain 41 128 2.1E-9 T 09-03-2017 IPR026956 D-serine dehydratase-like domain ARZXY2_RS19010 6e578d11454dc582232ab25539833d75 164 SMART SM01119 36 130 2.1E-18 T 09-03-2017 IPR026956 D-serine dehydratase-like domain ARZXY2_RS09990 96e9b308a2d4c6fd27c4650718ab3857 312 SUPERFAMILY SSF52540 8 228 3.73E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09990 96e9b308a2d4c6fd27c4650718ab3857 312 SMART SM00382 32 212 6.8E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09990 96e9b308a2d4c6fd27c4650718ab3857 312 Gene3D G3DSA:3.40.50.300 5 232 5.9E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09990 96e9b308a2d4c6fd27c4650718ab3857 312 Pfam PF00005 ABC transporter 23 166 2.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 SUPERFAMILY SSF53474 99 156 2.19E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 SUPERFAMILY SSF53474 202 256 2.19E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 SUPERFAMILY SSF53474 355 501 2.19E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 Pfam PF00561 alpha/beta hydrolase fold 105 487 6.0E-34 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 Gene3D G3DSA:3.40.50.1820 339 340 1.3E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 Gene3D G3DSA:3.40.50.1820 200 304 1.3E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 Gene3D G3DSA:3.40.50.1820 71 155 1.3E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS14955 19b1a290521de483825377e293feee80 514 Gene3D G3DSA:3.40.50.1820 383 502 1.3E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 145 3.7E-30 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 Gene3D G3DSA:3.40.390.30 5 149 3.0E-40 T 09-03-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 116 126 - T 09-03-2017 IPR020549 Endoribonuclease YbeY, conserved site ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 SUPERFAMILY SSF55486 3 145 5.31E-36 T 09-03-2017 ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 151 20.472 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ARZXY2_RS08305 99dc9c350a3d758a51fe3da28bc30d3c 157 Pfam PF02130 Uncharacterized protein family UPF0054 23 146 5.0E-34 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 320 9.6E-87 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 SUPERFAMILY SSF54782 240 326 1.31E-19 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 1.5E-20 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 PRINTS PR00151 Porphobilinogen deaminase signature 40 60 1.5E-20 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 1.5E-20 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 1.5E-20 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Gene3D G3DSA:3.30.160.40 241 325 7.5E-22 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 219 1.9E-67 T 09-03-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Gene3D G3DSA:3.40.190.10 106 208 2.0E-34 T 09-03-2017 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 246 318 4.3E-17 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 PIRSF PIRSF001438 1 331 9.6E-107 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Gene3D G3DSA:3.40.190.10 3 105 4.3E-35 T 09-03-2017 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 SUPERFAMILY SSF53850 3 221 1.19E-63 T 09-03-2017 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 320 31.808 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04480 051eba585d62c45beaa127f783aec86b 331 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 251 267 - T 09-03-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS13665 e843b7233ad36979b064c6d5fd208377 143 Gene3D G3DSA:3.10.180.10 1 142 3.7E-34 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS13665 e843b7233ad36979b064c6d5fd208377 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 126 1.6E-10 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS13665 e843b7233ad36979b064c6d5fd208377 143 SUPERFAMILY SSF54593 3 137 3.22E-27 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS17375 65f539438db0709a72d7134e17423c66 611 Pfam PF04183 IucA / IucC family 159 409 1.3E-78 T 09-03-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 ARZXY2_RS17375 65f539438db0709a72d7134e17423c66 611 Pfam PF06276 Ferric iron reductase FhuF-like transporter 431 587 3.0E-39 T 09-03-2017 IPR022770 Ferric iron reductase FhuF domain ARZXY2_RS09225 a0fa629ba5cbb0ba98a54d4b3a58a121 298 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 31 296 38.223 T 09-03-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 ARZXY2_RS09225 a0fa629ba5cbb0ba98a54d4b3a58a121 298 Pfam PF03301 Tryptophan 2,3-dioxygenase 26 168 5.4E-40 T 09-03-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 ARZXY2_RS09225 a0fa629ba5cbb0ba98a54d4b3a58a121 298 Pfam PF03301 Tryptophan 2,3-dioxygenase 222 294 7.0E-20 T 09-03-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 ARZXY2_RS09225 a0fa629ba5cbb0ba98a54d4b3a58a121 298 SUPERFAMILY SSF140959 37 296 1.44E-95 T 09-03-2017 ARZXY2_RS09225 a0fa629ba5cbb0ba98a54d4b3a58a121 298 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 31 296 1.2E-121 T 09-03-2017 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Gene3D G3DSA:3.30.70.870 334 433 4.9E-35 T 09-03-2017 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 PRINTS PR00315 GTP-binding elongation factor signature 139 148 7.4E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 PRINTS PR00315 GTP-binding elongation factor signature 87 97 7.4E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 PRINTS PR00315 GTP-binding elongation factor signature 103 114 7.4E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 PRINTS PR00315 GTP-binding elongation factor signature 16 29 7.4E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 PRINTS PR00315 GTP-binding elongation factor signature 60 68 7.4E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 SUPERFAMILY SSF54980 430 544 3.93E-27 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Pfam PF00679 Elongation factor G C-terminus 428 510 1.8E-21 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Pfam PF00009 Elongation factor Tu GTP binding domain 14 226 3.1E-50 T 09-03-2017 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Pfam PF03144 Elongation factor Tu domain 2 250 320 2.1E-11 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Gene3D G3DSA:2.40.50.250 514 608 4.4E-37 T 09-03-2017 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Gene3D G3DSA:3.40.50.300 10 236 3.2E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 SUPERFAMILY SSF52540 11 233 3.74E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 14 630 1.2E-271 T 09-03-2017 IPR006298 GTP-binding protein TypA GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 SUPERFAMILY SSF54980 334 419 7.67E-11 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 159 8.8E-22 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Gene3D G3DSA:2.40.30.10 237 333 1.1E-28 T 09-03-2017 ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 SUPERFAMILY SSF50447 211 332 9.94E-32 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 Gene3D G3DSA:3.30.70.240 434 512 2.6E-30 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS04235 3f8aaaabd8f9869c197de421f534f232 638 SMART SM00838 427 515 0.0062 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 PIRSF PIRSF001586 20 253 1.6E-80 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 23 248 7.8E-75 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 23 228 1.4E-33 T 09-03-2017 ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 22 249 36.853 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 SMART SM01211 21 251 3.2E-112 T 09-03-2017 ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 SUPERFAMILY SSF52317 20 248 1.11E-65 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS15910 b5c61d8d02ae335de88538d36b63a3e7 256 Gene3D G3DSA:3.40.50.880 23 248 4.7E-36 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 424 432 - T 09-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Gene3D G3DSA:2.40.30.10 46 140 1.1E-25 T 09-03-2017 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Pfam PF00970 Oxidoreductase FAD-binding domain 73 149 2.5E-9 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 398 465 1.1E-8 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 SUPERFAMILY SSF54292 382 473 1.7E-21 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Gene3D G3DSA:3.40.50.80 141 281 5.6E-29 T 09-03-2017 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 PRINTS PR00410 Phenol hydroxylase reductase family signature 77 89 3.6E-9 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 PRINTS PR00410 Phenol hydroxylase reductase family signature 253 261 3.6E-9 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 PRINTS PR00410 Phenol hydroxylase reductase family signature 160 179 3.6E-9 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 SUPERFAMILY SSF63380 44 148 9.14E-25 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 SUPERFAMILY SSF52343 139 283 1.31E-29 T 09-03-2017 ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Gene3D G3DSA:3.10.20.30 378 473 1.7E-23 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS16375 98ab1332a1a23483a1acf7e25d7da87f 474 Pfam PF00175 Oxidoreductase NAD-binding domain 161 264 4.8E-13 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 ARZXY2_RS06270 53442b61e36700f3fdc2e41a43a2e8e8 215 Pfam PF00565 Staphylococcal nuclease homologue 95 198 3.2E-9 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS06270 53442b61e36700f3fdc2e41a43a2e8e8 215 SUPERFAMILY SSF50199 59 208 2.35E-21 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS06270 53442b61e36700f3fdc2e41a43a2e8e8 215 SMART SM00318 58 208 1.8E-5 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS06270 53442b61e36700f3fdc2e41a43a2e8e8 215 Gene3D G3DSA:2.40.50.90 56 174 2.4E-20 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS07435 0712e5fd691dedb7203a729f77a6da4d 174 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 5.0E-58 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS07435 0712e5fd691dedb7203a729f77a6da4d 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 158 33.523 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS07435 0712e5fd691dedb7203a729f77a6da4d 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 153 5.1E-53 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS07435 0712e5fd691dedb7203a729f77a6da4d 174 Gene3D G3DSA:3.30.1060.10 1 153 1.8E-62 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS07435 0712e5fd691dedb7203a729f77a6da4d 174 SUPERFAMILY SSF55068 1 164 1.24E-66 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS14720 5aa4899412bf30baef2b4b0cb6eb4c07 305 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 4 305 16.619 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS14720 5aa4899412bf30baef2b4b0cb6eb4c07 305 Gene3D G3DSA:3.40.1190.20 17 303 1.5E-58 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS14720 5aa4899412bf30baef2b4b0cb6eb4c07 305 SUPERFAMILY SSF53613 16 302 5.89E-50 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS14720 5aa4899412bf30baef2b4b0cb6eb4c07 305 Pfam PF01256 Carbohydrate kinase 34 297 9.2E-35 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS14720 5aa4899412bf30baef2b4b0cb6eb4c07 305 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 27 300 2.2E-40 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS20110 bcdc8f7d116783ec48616718fb26d0d3 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 125 488 5.6E-55 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS20110 bcdc8f7d116783ec48616718fb26d0d3 575 Gene3D G3DSA:3.10.105.10 334 529 5.5E-33 T 09-03-2017 ARZXY2_RS20110 bcdc8f7d116783ec48616718fb26d0d3 575 Gene3D G3DSA:3.40.190.10 235 333 3.4E-24 T 09-03-2017 ARZXY2_RS20110 bcdc8f7d116783ec48616718fb26d0d3 575 SUPERFAMILY SSF53850 107 557 3.62E-75 T 09-03-2017 ARZXY2_RS20110 bcdc8f7d116783ec48616718fb26d0d3 575 Gene3D G3DSA:3.90.76.10 108 209 1.2E-11 T 09-03-2017 ARZXY2_RS03440 82f1ff7cc8ccca41558f7069a615c051 158 SUPERFAMILY SSF55826 9 154 2.35E-32 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS03440 82f1ff7cc8ccca41558f7069a615c051 158 Gene3D G3DSA:3.90.960.10 11 156 3.0E-34 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS03440 82f1ff7cc8ccca41558f7069a615c051 158 Pfam PF04073 Aminoacyl-tRNA editing domain 27 143 8.6E-26 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 Gene3D G3DSA:3.40.50.720 48 293 9.2E-85 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 141 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 221 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 71 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 240 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 192 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 258 278 5.9E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 SUPERFAMILY SSF51735 51 293 7.33E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 189 217 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 293 8.5E-65 T 09-03-2017 ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 202 221 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 141 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14735 da03d6a812ad556665c6aac650f52382 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 190 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 SUPERFAMILY SSF53748 13 407 8.36E-129 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 Gene3D G3DSA:3.40.50.1260 13 189 1.0E-55 T 09-03-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 177 199 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 200 219 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 384 401 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 327 352 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 360 371 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PRINTS PR00477 Phosphoglycerate kinase family signature 147 169 1.4E-75 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 Gene3D G3DSA:3.40.50.1270 190 396 6.4E-77 T 09-03-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 408 38.804 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 PIRSF PIRSF000724 2 408 1.0E-121 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09070 ff2f89a8f2e7680e5341ea094b14dff6 408 Pfam PF00162 Phosphoglycerate kinase 14 398 2.4E-134 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07010 b8935df9677cf4c8e10b1de3212084ea 80 Gene3D G3DSA:3.30.300.120 6 65 9.9E-8 T 09-03-2017 ARZXY2_RS07010 b8935df9677cf4c8e10b1de3212084ea 80 SUPERFAMILY SSF54814 16 60 6.1E-7 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 ARZXY2_RS07010 b8935df9677cf4c8e10b1de3212084ea 80 Pfam PF13083 KH domain 4 73 2.6E-21 T 09-03-2017 ARZXY2_RS07010 b8935df9677cf4c8e10b1de3212084ea 80 Hamap MF_00088 UPF0109 protein . 2 74 21.144 T 09-03-2017 IPR020627 Uncharacterised protein family UPF0109 ARZXY2_RS09245 71738c171aba7807fee8264f472670f9 373 SUPERFAMILY SSF89392 93 264 2.08E-13 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX ARZXY2_RS09245 71738c171aba7807fee8264f472670f9 373 Gene3D G3DSA:2.50.20.10 94 262 6.3E-16 T 09-03-2017 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 SUPERFAMILY SSF46946 141 223 2.75E-24 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 Gene3D G3DSA:3.20.190.10 2 141 1.8E-13 T 09-03-2017 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 Pfam PF06827 Zinc finger found in FPG and IleRS 248 276 5.7E-7 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 141 225 1.9E-21 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 SUPERFAMILY SSF81624 2 150 9.68E-19 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 SMART SM00898 2 127 4.7E-11 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 SMART SM01232 141 233 5.9E-32 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 Gene3D G3DSA:1.10.8.50 142 276 6.8E-36 T 09-03-2017 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 SUPERFAMILY SSF57716 234 276 1.17E-9 T 09-03-2017 ARZXY2_RS07610 10e5acea47f967b6f0af2cd903f5f3ff 291 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 86 1.4E-13 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS15585 e1a2d54a147488dbb74bea1e14e401b1 504 Pfam PF12844 Helix-turn-helix domain 37 96 2.9E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS15585 e1a2d54a147488dbb74bea1e14e401b1 504 Pfam PF06114 Domain of unknown function (DUF955) 229 328 6.7E-9 T 09-03-2017 IPR010359 HTH domain, IrrE-type ARZXY2_RS15585 e1a2d54a147488dbb74bea1e14e401b1 504 SUPERFAMILY SSF47413 33 100 7.04E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15585 e1a2d54a147488dbb74bea1e14e401b1 504 Gene3D G3DSA:1.10.260.40 35 100 2.0E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15585 e1a2d54a147488dbb74bea1e14e401b1 504 SMART SM00530 39 94 5.1E-15 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS17350 01ca3051ada4aa1b091bc1a34ca07119 310 Pfam PF00892 EamA-like transporter family 21 152 2.4E-14 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS17350 01ca3051ada4aa1b091bc1a34ca07119 310 Pfam PF00892 EamA-like transporter family 164 294 1.1E-18 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS17350 01ca3051ada4aa1b091bc1a34ca07119 310 SUPERFAMILY SSF103481 57 156 1.44E-7 T 09-03-2017 ARZXY2_RS17350 01ca3051ada4aa1b091bc1a34ca07119 310 SUPERFAMILY SSF103481 199 295 1.83E-12 T 09-03-2017 ARZXY2_RS15870 a2006ca030a190af944ffe432aad9d51 299 Gene3D G3DSA:1.20.1250.20 89 286 7.0E-20 T 09-03-2017 ARZXY2_RS15870 a2006ca030a190af944ffe432aad9d51 299 Pfam PF07690 Major Facilitator Superfamily 27 235 4.8E-17 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS15870 a2006ca030a190af944ffe432aad9d51 299 SUPERFAMILY SSF103473 36 287 1.57E-26 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Gene3D G3DSA:3.90.980.10 118 243 1.1E-39 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Pfam PF13662 Toprim domain 263 334 1.3E-17 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Gene3D G3DSA:3.40.1360.10 244 372 3.7E-40 T 09-03-2017 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 TIGRFAM TIGR01391 dnaG: DNA primase 5 422 1.5E-115 T 09-03-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Hamap MF_00974 DNA primase [dnaG]. 4 615 26.199 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Pfam PF08278 DNA primase DnaG DnaB-binding 482 608 8.9E-13 T 09-03-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Gene3D G3DSA:1.20.50.20 374 431 4.1E-12 T 09-03-2017 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 254 5.0E-37 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 SUPERFAMILY SSF57783 5 101 4.08E-31 T 09-03-2017 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 SMART SM00400 37 91 2.4E-31 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 SMART SM00493 262 339 5.5E-15 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Pfam PF10410 DnaB-helicase binding domain of primase 375 428 9.3E-17 T 09-03-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 PIRSF PIRSF002811 2 624 3.6E-147 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 SUPERFAMILY SSF56731 118 429 3.66E-95 T 09-03-2017 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Gene3D G3DSA:3.90.580.10 4 102 2.7E-35 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ARZXY2_RS12175 cb0995fe2c0ed61e566b698e06f69a41 627 Pfam PF01807 CHC2 zinc finger 6 101 4.6E-33 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 Gene3D G3DSA:3.40.190.10 90 176 4.5E-12 T 09-03-2017 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 SUPERFAMILY SSF53850 89 298 1.86E-30 T 09-03-2017 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.3E-22 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 Gene3D G3DSA:1.10.10.10 1 82 6.1E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 Gene3D G3DSA:3.40.190.10 177 265 5.4E-12 T 09-03-2017 ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 SUPERFAMILY SSF46785 1 109 3.58E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19940 fa8c02d60c636b085a61af98951ea798 314 Pfam PF03466 LysR substrate binding domain 88 293 3.4E-31 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 Gene3D G3DSA:3.40.190.10 7 95 1.1E-24 T 09-03-2017 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 Gene3D G3DSA:3.40.190.10 96 175 5.8E-21 T 09-03-2017 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 Pfam PF01842 ACT domain 208 265 1.4E-6 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 SUPERFAMILY SSF53850 7 194 9.41E-48 T 09-03-2017 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 SUPERFAMILY SSF55021 182 280 6.7E-23 T 09-03-2017 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 Gene3D G3DSA:3.30.70.260 193 281 2.0E-28 T 09-03-2017 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 09-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 PIRSF PIRSF001500 3 283 9.7E-59 T 09-03-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS18165 4b625ac322377a63232a0656595dc4d9 310 Pfam PF00800 Prephenate dehydratase 8 187 3.1E-48 T 09-03-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Pfam PF08029 HisG, C-terminal domain 211 282 1.0E-26 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 3.9E-53 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 194 285 1.3E-29 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 286 33.055 T 09-03-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Gene3D G3DSA:3.40.190.10 1 108 1.3E-33 T 09-03-2017 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Gene3D G3DSA:3.40.190.10 109 173 1.2E-25 T 09-03-2017 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 09-03-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 SUPERFAMILY SSF53850 1 212 2.67E-63 T 09-03-2017 ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Gene3D G3DSA:3.30.70.120 214 285 6.1E-28 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 SUPERFAMILY SSF54913 213 285 5.45E-22 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta ARZXY2_RS10305 d7a995b5f24594b3d722e2d4b2a28543 286 Pfam PF01634 ATP phosphoribosyltransferase 49 207 5.0E-42 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 ARZXY2_RS03175 f28e242df2b7bd27f2ef64e4564cae77 218 SUPERFAMILY SSF51735 1 204 8.45E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03175 f28e242df2b7bd27f2ef64e4564cae77 218 Gene3D G3DSA:3.40.50.720 1 207 8.1E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03175 f28e242df2b7bd27f2ef64e4564cae77 218 Pfam PF13460 NAD(P)H-binding 8 193 8.4E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 SUPERFAMILY SSF48208 286 747 3.06E-112 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Gene3D G3DSA:2.60.420.10 680 753 1.6E-21 T 09-03-2017 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 697 752 1.2E-12 T 09-03-2017 IPR005194 Glycoside hydrolase family 65, C-terminal ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 25 274 3.3E-44 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 PIRSF PIRSF036289 6 764 1.5E-174 T 09-03-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Gene3D G3DSA:1.50.10.10 327 679 5.2E-118 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 333 691 9.4E-110 T 09-03-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 SUPERFAMILY SSF74650 9 274 7.85E-53 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS17170 620e44d8edc99c068b9a04d9e2354c6c 787 Gene3D G3DSA:2.70.98.40 11 274 1.3E-57 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ARZXY2_RS17330 2bd2ec6757955e4123a54f3e77e98426 291 Gene3D G3DSA:1.10.3720.10 57 279 2.7E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17330 2bd2ec6757955e4123a54f3e77e98426 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 285 9.8E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17330 2bd2ec6757955e4123a54f3e77e98426 291 SUPERFAMILY SSF161098 50 277 3.53E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17330 2bd2ec6757955e4123a54f3e77e98426 291 Gene3D G3DSA:1.20.58.370 6 35 4.2E-4 T 09-03-2017 ARZXY2_RS17330 2bd2ec6757955e4123a54f3e77e98426 291 SUPERFAMILY SSF160964 6 37 4.71E-5 T 09-03-2017 ARZXY2_RS08730 39b31263773d4d08ca5d765d79f7a8dc 434 Pfam PF04932 O-Antigen ligase 237 362 1.8E-10 T 09-03-2017 IPR007016 O-antigen ligase-related ARZXY2_RS14790 81aa9787c8cdff866fe6e42088ecd840 159 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 18 137 5.9E-26 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS14790 81aa9787c8cdff866fe6e42088ecd840 159 SUPERFAMILY SSF50475 14 138 1.23E-28 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS14790 81aa9787c8cdff866fe6e42088ecd840 159 Gene3D G3DSA:2.30.110.10 9 146 8.7E-44 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS13155 710d960411b52236099c83dd1bf0164e 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 102 1.2E-13 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 ARZXY2_RS13155 710d960411b52236099c83dd1bf0164e 132 SUPERFAMILY SSF53927 1 128 1.24E-42 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS13155 710d960411b52236099c83dd1bf0164e 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 8 127 4.9E-38 T 09-03-2017 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-73614 ARZXY2_RS13155 710d960411b52236099c83dd1bf0164e 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 96 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ARZXY2_RS13155 710d960411b52236099c83dd1bf0164e 132 Gene3D G3DSA:3.40.140.10 5 129 5.7E-46 T 09-03-2017 ARZXY2_RS06335 2d266c0205a683c52047deac725ef8cb 477 Gene3D G3DSA:2.30.42.10 160 277 6.9E-18 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS06335 2d266c0205a683c52047deac725ef8cb 477 SUPERFAMILY SSF50156 164 276 1.28E-13 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS06335 2d266c0205a683c52047deac725ef8cb 477 SMART SM00228 185 271 0.0016 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS06335 2d266c0205a683c52047deac725ef8cb 477 Pfam PF02163 Peptidase family M50 9 428 3.1E-42 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 ARZXY2_RS06335 2d266c0205a683c52047deac725ef8cb 477 Pfam PF13180 PDZ domain 219 277 2.5E-6 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS09695 105865e0fee81946dbf4729e8c50b597 294 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09695 105865e0fee81946dbf4729e8c50b597 294 SUPERFAMILY SSF52540 10 241 7.56E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09695 105865e0fee81946dbf4729e8c50b597 294 Gene3D G3DSA:3.40.50.300 9 242 4.5E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09695 105865e0fee81946dbf4729e8c50b597 294 Pfam PF00005 ABC transporter 27 182 1.5E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS09695 105865e0fee81946dbf4729e8c50b597 294 SMART SM00382 36 233 1.2E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Gene3D G3DSA:3.40.50.300 52 270 3.8E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 SMART SM00487 77 281 1.1E-62 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 53 601 44.245 T 09-03-2017 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Pfam PF03880 DbpA RNA binding domain 529 599 8.1E-21 T 09-03-2017 IPR005580 DbpA, RNA-binding domain ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Pfam PF00271 Helicase conserved C-terminal domain 290 398 1.4E-27 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Pfam PF00270 DEAD/DEAH box helicase 83 252 2.9E-48 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 Gene3D G3DSA:3.40.50.300 271 435 1.3E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 SMART SM00490 317 398 5.6E-34 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 SUPERFAMILY SSF52540 132 419 1.21E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03155 d1d6070ccd54b7cd5c9bc29f37594bc6 694 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 212 220 - T 09-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 116 151 - T 09-03-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 5 154 1.2E-51 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 SUPERFAMILY SSF53098 3 159 6.45E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 3 157 42.714 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 Gene3D G3DSA:3.30.420.10 4 158 4.5E-53 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 86 102 6.6E-37 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 6 19 6.6E-37 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 110 129 6.6E-37 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 64 80 6.6E-37 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 142 154 6.6E-37 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS07970 fda47e864692ed056da7c07765cfa3ed 191 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 5 158 6.3E-35 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 PIRSF PIRSF039085 6 245 3.0E-99 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 SMART SM00382 33 218 1.5E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 Pfam PF00005 ABC transporter 24 170 1.3E-38 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 SUPERFAMILY SSF52540 9 240 1.68E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04510 ee415abc7b119e8cad7844a2e899233b 245 Gene3D G3DSA:3.40.50.300 9 241 2.1E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17240 67bd2d40359039c81cba7eb52e5b6c05 60 Gene3D G3DSA:3.30.1340.10 1 52 6.3E-12 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17240 67bd2d40359039c81cba7eb52e5b6c05 60 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site ARZXY2_RS17240 67bd2d40359039c81cba7eb52e5b6c05 60 SUPERFAMILY SSF55594 1 43 1.57E-10 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17240 67bd2d40359039c81cba7eb52e5b6c05 60 Pfam PF00381 PTS HPr component phosphorylation site 3 53 1.7E-12 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17240 67bd2d40359039c81cba7eb52e5b6c05 60 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 53 2.1E-13 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 197 207 - T 09-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 SUPERFAMILY SSF51161 297 412 1.39E-18 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 SUPERFAMILY SSF53448 348 365 1.1E-68 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 SUPERFAMILY SSF53448 4 281 1.1E-68 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 384 1.5E-136 T 09-03-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 97 105 - T 09-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 Gene3D G3DSA:3.90.550.10 6 288 1.8E-71 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 Gene3D G3DSA:3.90.550.10 331 374 1.8E-71 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 Pfam PF00483 Nucleotidyl transferase 8 277 5.2E-68 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ARZXY2_RS08845 b85a8d19e652a9c0cc98fc0ede721664 468 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 411 46.246 T 09-03-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 SUPERFAMILY SSF103473 20 402 5.49E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 Pfam PF07690 Major Facilitator Superfamily 34 363 1.9E-32 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 Gene3D G3DSA:1.20.1250.20 230 401 9.2E-10 T 09-03-2017 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 Gene3D G3DSA:1.20.1250.20 28 210 5.9E-30 T 09-03-2017 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 PRINTS PR01035 Tetracycline resistance protein signature 39 55 5.1E-12 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 PRINTS PR01035 Tetracycline resistance protein signature 153 175 5.1E-12 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS20255 f1cda8935182dcdba2785aa10a69aa5c 413 PRINTS PR01035 Tetracycline resistance protein signature 181 201 5.1E-12 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS14610 ab2ea46933351f37343ed83cc3884121 339 Pfam PF01261 Xylose isomerase-like TIM barrel 19 236 1.3E-33 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14610 ab2ea46933351f37343ed83cc3884121 339 Pfam PF07582 AP endonuclease family 2 C terminus 286 327 1.2E-5 T 09-03-2017 IPR011418 AP endonuclease, family 2, C-terminal ARZXY2_RS14610 ab2ea46933351f37343ed83cc3884121 339 SUPERFAMILY SSF51658 266 327 1.96E-48 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14610 ab2ea46933351f37343ed83cc3884121 339 SUPERFAMILY SSF51658 1 227 1.96E-48 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14610 ab2ea46933351f37343ed83cc3884121 339 Gene3D G3DSA:3.20.20.150 1 327 4.6E-70 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 363 8.3E-149 T 09-03-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 Pfam PF03462 PCRF domain 29 219 2.8E-57 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 Gene3D G3DSA:3.30.160.20 227 305 2.4E-33 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 SMART SM00937 84 194 2.0E-49 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 Gene3D G3DSA:1.20.58.410 2 114 6.4E-31 T 09-03-2017 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 Pfam PF00472 RF-1 domain 228 336 1.0E-35 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 SUPERFAMILY SSF75620 29 365 4.71E-121 T 09-03-2017 ARZXY2_RS04950 156d21997f45d8b60f9c22381c1094da 371 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 36.911 T 09-03-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS01580 d4e786dc356fa21a21d9cb43252be6e2 499 TIGRFAM TIGR03173 pbuX: xanthine permease 33 441 2.8E-154 T 09-03-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 ARZXY2_RS01580 d4e786dc356fa21a21d9cb43252be6e2 499 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 25 439 6.3E-100 T 09-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ARZXY2_RS01580 d4e786dc356fa21a21d9cb43252be6e2 499 Pfam PF00860 Permease family 29 408 2.7E-85 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS01580 d4e786dc356fa21a21d9cb43252be6e2 499 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 356 376 - T 09-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ARZXY2_RS04690 88dc65f7d48cb21c79d0f091ea821dc5 542 Gene3D G3DSA:3.90.76.10 51 212 3.1E-27 T 09-03-2017 ARZXY2_RS04690 88dc65f7d48cb21c79d0f091ea821dc5 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 462 1.6E-72 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS04690 88dc65f7d48cb21c79d0f091ea821dc5 542 Gene3D G3DSA:3.10.105.10 288 511 4.8E-49 T 09-03-2017 ARZXY2_RS04690 88dc65f7d48cb21c79d0f091ea821dc5 542 PIRSF PIRSF002741 1 536 3.8E-66 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ARZXY2_RS04690 88dc65f7d48cb21c79d0f091ea821dc5 542 SUPERFAMILY SSF53850 38 535 5.29E-98 T 09-03-2017 ARZXY2_RS00205 0c507d5541fd862d727f87312ba91e39 388 Gene3D G3DSA:3.20.20.150 13 375 1.3E-90 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00205 0c507d5541fd862d727f87312ba91e39 388 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 10 378 3.5E-192 T 09-03-2017 IPR013457 Rhamnose isomerase-related ARZXY2_RS00205 0c507d5541fd862d727f87312ba91e39 388 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 4 328 3.0E-6 T 09-03-2017 ARZXY2_RS00205 0c507d5541fd862d727f87312ba91e39 388 SUPERFAMILY SSF51658 25 360 5.85E-94 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00205 0c507d5541fd862d727f87312ba91e39 388 Pfam PF06134 L-rhamnose isomerase (RhaA) 79 338 1.4E-7 T 09-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 ARZXY2_RS16890 892d320b72c0543930b8f327d8336ec3 480 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 66 212 5.8E-45 T 09-03-2017 IPR009827 Dicarboxylate carrier MatC N-terminal ARZXY2_RS00075 0345ca55043e2e33643c4645da8f42fe 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 293 6.0E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS00075 0345ca55043e2e33643c4645da8f42fe 326 SUPERFAMILY SSF161098 75 279 3.01E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS00075 0345ca55043e2e33643c4645da8f42fe 326 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 74 136 4.3E-13 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS00075 0345ca55043e2e33643c4645da8f42fe 326 Gene3D G3DSA:1.10.3720.10 68 294 4.9E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20180 3a088faed44b95574b69679e725a85e9 264 Gene3D G3DSA:3.40.50.1820 37 262 6.7E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS20180 3a088faed44b95574b69679e725a85e9 264 Pfam PF12697 Alpha/beta hydrolase family 45 256 1.2E-15 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS20180 3a088faed44b95574b69679e725a85e9 264 SUPERFAMILY SSF53474 37 261 2.22E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Gene3D G3DSA:3.40.50.980 168 329 3.6E-30 T 09-03-2017 ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 497 5.7E-17 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Pfam PF00501 AMP-binding enzyme 12 411 2.4E-85 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Gene3D G3DSA:2.30.38.10 330 401 2.3E-24 T 09-03-2017 ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 SUPERFAMILY SSF56801 2 504 1.44E-132 T 09-03-2017 ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Gene3D G3DSA:3.30.300.30 406 504 2.5E-30 T 09-03-2017 ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS16975 b2ab5466492564b29908843b566f0017 511 Gene3D G3DSA:3.40.50.980 2 167 9.5E-30 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 500 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 610 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 627 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 151 165 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 301 315 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 521 1.7E-39 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 566 671 2.7E-30 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 320 8.5E-44 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 605 1.2E-22 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Gene3D G3DSA:2.70.150.10 10 46 1.8E-33 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Gene3D G3DSA:2.70.150.10 99 200 1.8E-33 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 61 3.1E-12 T 09-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF81665 202 295 1.83E-94 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF81665 10 104 1.83E-94 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF81665 641 859 1.83E-94 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF56784 300 319 2.12E-51 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF56784 441 696 2.12E-51 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SUPERFAMILY SSF81653 103 199 1.7E-26 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Gene3D G3DSA:3.40.1110.10 291 496 2.8E-39 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Pfam PF00122 E1-E2 ATPase 71 292 3.2E-61 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Gene3D G3DSA:1.20.1110.10 560 857 7.1E-82 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Gene3D G3DSA:1.20.1110.10 47 98 7.1E-82 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 303 309 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 SMART SM00831 3 66 8.8E-10 T 09-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 Pfam PF00689 Cation transporting ATPase, C-terminus 677 858 8.3E-35 T 09-03-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 294 315 9.0E-14 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 423 441 9.0E-14 T 09-03-2017 ARZXY2_RS09810 63ea02756eacbaa6632ee37e66f79c22 873 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 53 67 9.0E-14 T 09-03-2017 ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 SUPERFAMILY SSF56801 29 372 1.7E-63 T 09-03-2017 ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 Pfam PF00501 AMP-binding enzyme 36 279 3.6E-38 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 ProSitePatterns PS00455 Putative AMP-binding domain signature. 46 57 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 Gene3D G3DSA:2.30.38.10 204 273 4.3E-13 T 09-03-2017 ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 Gene3D G3DSA:3.40.50.980 41 203 4.1E-23 T 09-03-2017 ARZXY2_RS02215 d3ec29d8d88767c7843ff5d0bf45629c 379 Gene3D G3DSA:3.30.300.30 274 371 1.8E-11 T 09-03-2017 ARZXY2_RS19125 7f03d534fe4d7f5217bd12739407975a 203 SUPERFAMILY SSF46689 4 66 3.04E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19125 7f03d534fe4d7f5217bd12739407975a 203 Gene3D G3DSA:1.10.357.10 2 196 4.9E-24 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS19125 7f03d534fe4d7f5217bd12739407975a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 5.5E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS19125 7f03d534fe4d7f5217bd12739407975a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 5.5E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS19125 7f03d534fe4d7f5217bd12739407975a 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.7E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS18855 6c11fdfe771708240800cc5116ad48a7 127 Gene3D G3DSA:3.10.180.10 4 120 1.5E-10 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS18855 6c11fdfe771708240800cc5116ad48a7 127 SUPERFAMILY SSF54593 1 121 2.54E-14 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 PIRSF PIRSF036625 3 243 7.4E-31 T 09-03-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 Gene3D G3DSA:1.10.10.10 180 235 5.8E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 SUPERFAMILY SSF52172 161 232 4.92E-7 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 Pfam PF03861 ANTAR domain 180 232 7.0E-16 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 SMART SM01012 177 232 5.5E-18 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 Gene3D G3DSA:3.30.450.40 42 168 7.1E-5 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09480 72c8fb9e1fecbb1cde92afedb37b501d 252 SUPERFAMILY SSF55781 31 168 6.87E-9 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 SUPERFAMILY SSF46785 16 85 2.29E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 Pfam PF12840 Helix-turn-helix domain 15 69 1.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 SMART SM00226 97 220 2.3E-23 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 Gene3D G3DSA:1.10.10.10 16 83 2.8E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 SMART SM00418 13 94 1.5E-4 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 Gene3D G3DSA:3.40.50.270 97 217 1.7E-29 T 09-03-2017 ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 SUPERFAMILY SSF52788 97 221 7.85E-30 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS17690 b8ab2d9a1cb87e76198c3baee2c85382 224 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 99 217 9.8E-19 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 SUPERFAMILY SSF47819 237 324 1.31E-21 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 Pfam PF01612 3'-5' exonuclease 48 210 9.1E-28 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 SMART SM00474 45 211 6.6E-31 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 SUPERFAMILY SSF53098 10 247 6.32E-50 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 Pfam PF00570 HRDC domain 253 320 4.1E-15 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 SMART SM00341 250 330 3.3E-14 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 ARZXY2_RS10475 fcfdc640ff0345b06ed2ab7b1f857998 441 Gene3D G3DSA:3.30.420.10 48 218 7.7E-8 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.7E-17 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 SUPERFAMILY SSF46785 2 112 5.2E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 SUPERFAMILY SSF53850 88 299 4.16E-28 T 09-03-2017 ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 Gene3D G3DSA:1.10.10.10 1 80 6.5E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 Gene3D G3DSA:3.40.190.10 92 182 8.6E-9 T 09-03-2017 ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 Gene3D G3DSA:3.40.190.10 183 266 5.8E-16 T 09-03-2017 ARZXY2_RS07785 7f73c4d95b44d4d4ad8e1098ba3c7ec7 321 Pfam PF03466 LysR substrate binding domain 88 297 3.4E-29 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 Gene3D G3DSA:1.10.10.10 78 159 6.1E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 129 135 - T 09-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 81 158 2.7E-31 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 SUPERFAMILY SSF46767 79 159 4.58E-30 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 75 1.5E-6 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 80 158 1.4E-31 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18465 54b2392c974e74931c67cdfd801e1367 169 SUPERFAMILY SSF53155 4 83 1.43E-14 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Pfam PF00005 ABC transporter 342 471 2.9E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Pfam PF00005 ABC transporter 18 187 1.0E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 SUPERFAMILY SSF52540 305 516 8.32E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Gene3D G3DSA:3.40.50.300 135 282 2.6E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Gene3D G3DSA:3.40.50.300 2 102 2.6E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 SMART SM00382 26 231 9.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 SMART SM00382 350 515 1.2E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 SUPERFAMILY SSF52540 2 79 1.43E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 SUPERFAMILY SSF52540 128 233 1.43E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Gene3D G3DSA:3.40.50.300 326 505 5.6E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08945 13be5730128a28ca83332262135de582 532 Pfam PF12848 ABC transporter 230 305 3.0E-8 T 09-03-2017 IPR032781 ABC-transporter extension domain ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 Pfam PF00294 pfkB family carbohydrate kinase 2 294 4.3E-22 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 Gene3D G3DSA:3.40.50.620 344 462 1.5E-34 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 334 473 2.8E-55 T 09-03-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 Gene3D G3DSA:3.40.1190.20 1 291 1.0E-39 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 345 410 7.1E-15 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 SUPERFAMILY SSF52374 345 469 9.19E-23 T 09-03-2017 ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 Pfam PF01467 Cytidylyltransferase-like 348 438 7.6E-15 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS18090 fe9ba2bc0c612d489d391358aa13a9a2 478 SUPERFAMILY SSF53613 1 289 6.08E-34 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 30.523 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 Gene3D G3DSA:3.90.230.10 1 255 4.7E-59 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 3.1E-14 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 3.1E-14 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 3.1E-14 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 3.1E-14 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 Pfam PF00557 Metallopeptidase family M24 14 246 1.8E-33 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 3.1E-65 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS08180 773e777f5ebfa143baff7b94be0dc2a0 260 SUPERFAMILY SSF55920 1 253 1.31E-62 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS00015 92fc84b2bc4b39642b4be8c9a81cf1d7 194 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 5 193 9.5E-96 T 09-03-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD ARZXY2_RS00015 92fc84b2bc4b39642b4be8c9a81cf1d7 194 Gene3D G3DSA:1.10.340.30 18 137 2.4E-10 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS00015 92fc84b2bc4b39642b4be8c9a81cf1d7 194 SUPERFAMILY SSF48150 20 143 1.48E-11 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS00015 92fc84b2bc4b39642b4be8c9a81cf1d7 194 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 188 8.9E-14 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 Pfam PF05235 CHAD domain 229 460 2.0E-42 T 09-03-2017 IPR007899 CHAD domain ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 Pfam PF01928 CYTH domain 7 176 4.1E-13 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 SUPERFAMILY SSF55154 4 208 3.27E-42 T 09-03-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 Gene3D G3DSA:2.40.320.10 4 207 5.0E-51 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 SMART SM01118 5 201 4.2E-17 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 ARZXY2_RS01415 7d75521d1daeac5acbe9279c05b791ee 507 SMART SM00880 229 492 8.3E-52 T 09-03-2017 IPR007899 CHAD domain ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 149 363 7.2E-48 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 Gene3D G3DSA:3.40.50.720 8 147 1.1E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 SUPERFAMILY SSF55347 139 364 2.15E-70 T 09-03-2017 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 SMART SM00859 8 127 1.7E-21 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 Gene3D G3DSA:3.30.360.10 148 360 5.5E-69 T 09-03-2017 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 8 376 2.6E-177 T 09-03-2017 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 PIRSF PIRSF000148 6 380 2.6E-60 T 09-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 125 4.2E-20 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 271 285 - T 09-03-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS03270 7d0ad5dcde64b4710bc6a08ff025d797 380 SUPERFAMILY SSF51735 8 152 1.05E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 SUPERFAMILY SSF52540 126 343 4.78E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 Pfam PF03193 Protein of unknown function, DUF258 107 282 6.5E-43 T 09-03-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 54 346 29.862 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 89 338 4.0E-44 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 Gene3D G3DSA:3.40.50.300 123 281 1.1E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04085 3d9496180116568db45134f07dcde09c 396 Gene3D G3DSA:1.10.40.50 287 352 1.4E-21 T 09-03-2017 ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 Pfam PF00005 ABC transporter 24 173 4.8E-36 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 Pfam PF08402 TOBE domain 281 318 2.0E-6 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 Gene3D G3DSA:3.40.50.300 4 248 3.7E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 SUPERFAMILY SSF50331 251 320 5.1E-9 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 SUPERFAMILY SSF52540 9 249 2.84E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15445 e7e0551d34cb4af69890a50004c09a65 370 SMART SM00382 33 223 9.3E-21 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 245 2.7E-56 T 09-03-2017 ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.5E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 SUPERFAMILY SSF51735 5 247 6.36E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17470 6c7b78b966ceb8b061be223d860e4511 262 Gene3D G3DSA:3.40.50.720 2 247 5.8E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03100 acd81bbb04c6f8203783215babe635ec 177 SUPERFAMILY SSF46785 6 146 4.49E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03100 acd81bbb04c6f8203783215babe635ec 177 Pfam PF01638 HxlR-like helix-turn-helix 20 108 4.8E-14 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type ARZXY2_RS03100 acd81bbb04c6f8203783215babe635ec 177 Gene3D G3DSA:1.10.10.10 4 112 3.3E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 419 51.532 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 SMART SM01086 321 415 1.3E-32 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 SMART SM00994 10 49 6.2E-24 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Gene3D G3DSA:3.40.50.300 62 261 1.4E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Gene3D G3DSA:3.40.50.300 298 315 1.4E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Gene3D G3DSA:1.10.8.60 321 419 4.7E-36 T 09-03-2017 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 SMART SM00382 119 272 7.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 SUPERFAMILY SSF52540 60 406 2.84E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Pfam PF06689 ClpX C4-type zinc finger 11 48 4.1E-21 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 SUPERFAMILY SSF57716 11 46 1.25E-11 T 09-03-2017 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 120 315 4.2E-49 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 416 2.8E-193 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 ARZXY2_RS07600 6841da8f0c870efa1eaaa7cbfc321936 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 321 398 9.6E-16 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 Pfam PF00005 ABC transporter 405 559 2.2E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 SUPERFAMILY SSF161098 76 267 2.22E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 ProSitePatterns PS00211 ABC transporters family signature. 532 546 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 611 667 5.4E-9 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 609 668 6.8E-11 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 Gene3D G3DSA:3.40.50.300 382 638 2.4E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 Gene3D G3DSA:1.10.3720.10 73 276 3.3E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 273 1.1E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 SMART SM00382 414 609 2.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS15145 de4a4b9c61b2a481aef8db178f0ec27f 705 SUPERFAMILY SSF52540 385 630 4.28E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 Pfam PF07883 Cupin domain 127 193 2.2E-13 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 SMART SM00530 21 76 1.7E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 SUPERFAMILY SSF47413 15 83 5.63E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 Gene3D G3DSA:2.60.120.10 121 196 2.5E-22 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 SUPERFAMILY SSF51182 69 196 1.59E-26 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 Pfam PF01381 Helix-turn-helix 23 73 8.5E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS13875 96c60a88eee737dad93184688c4acaf7 199 Gene3D G3DSA:1.10.260.40 17 120 4.6E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS02100 d4e11995c46f98758265de1ea34ef572 382 PIRSF PIRSF001361 17 380 3.3E-151 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 ARZXY2_RS02100 d4e11995c46f98758265de1ea34ef572 382 SUPERFAMILY SSF51569 27 376 2.83E-121 T 09-03-2017 ARZXY2_RS02100 d4e11995c46f98758265de1ea34ef572 382 Gene3D G3DSA:3.20.20.70 29 377 4.2E-142 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS02100 d4e11995c46f98758265de1ea34ef572 382 Pfam PF00793 DAHP synthetase I family 64 366 1.4E-94 T 09-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 ARZXY2_RS02100 d4e11995c46f98758265de1ea34ef572 382 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 27 377 3.3E-144 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 SUPERFAMILY SSF48498 82 182 1.61E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.6E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 SUPERFAMILY SSF46689 13 76 6.67E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 6.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 6.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS14990 42aae25579c89be79a89e3cbad073cd6 199 Gene3D G3DSA:1.10.357.10 13 189 1.5E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 323 1.8E-68 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF51230 1047 1123 3.8E-15 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF51246 334 451 1.41E-38 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF00682 HMGL-like 524 796 4.5E-23 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:3.30.1490.20 131 201 1.9E-21 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:2.40.50.100 1049 1123 1.3E-17 T 09-03-2017 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:3.40.50.20 1 130 2.6E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF02436 Conserved carboxylase domain 820 1006 6.0E-54 T 09-03-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 PIRSF PIRSF001594 1 1125 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF52440 1 112 6.76E-39 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF51569 519 828 2.75E-71 T 09-03-2017 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:3.10.600.10 958 1044 3.4E-31 T 09-03-2017 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:3.20.20.70 502 811 1.1E-122 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF00364 Biotin-requiring enzyme 1064 1122 5.4E-12 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1122 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Gene3D G3DSA:3.30.470.20 205 452 1.1E-101 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF56059 84 362 5.3E-71 T 09-03-2017 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 2.5E-35 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SUPERFAMILY SSF89000 825 989 1.92E-40 T 09-03-2017 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 3.2E-37 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS19495 c5eb052638c9a64da3e8f191976f53b5 1126 SMART SM00878 339 446 9.9E-56 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 SUPERFAMILY SSF48498 79 217 8.0E-43 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 3.6E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 SUPERFAMILY SSF46689 3 82 1.15E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 Gene3D G3DSA:1.10.357.10 5 195 7.2E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15530 e65cc5dc6df1da9e403c3d235fe8f405 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 SUPERFAMILY SSF52540 4 249 5.84E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 Gene3D G3DSA:3.40.50.300 4 239 2.0E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 SMART SM00382 28 233 3.2E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 SUPERFAMILY SSF50331 243 355 2.25E-13 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 Pfam PF00005 ABC transporter 19 167 2.7E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS09640 42f4d3c0e98df929e1b2f9695a38bf3f 367 Pfam PF08402 TOBE domain 282 346 2.2E-7 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 SUPERFAMILY SSF55973 257 407 8.63E-66 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 257 396 1.0E-65 T 09-03-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 139 149 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 283 291 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 PIRSF PIRSF000497 11 408 4.6E-162 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 SUPERFAMILY SSF55973 135 256 6.67E-43 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 18 406 3.5E-164 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 18 113 6.7E-41 T 09-03-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 15 407 53.603 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Gene3D G3DSA:3.30.300.10 26 147 1.2E-42 T 09-03-2017 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Pfam PF02772 S-adenosylmethionine synthetase, central domain 138 255 8.2E-42 T 09-03-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Gene3D G3DSA:3.30.300.10 152 257 2.4E-37 T 09-03-2017 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 Gene3D G3DSA:3.30.300.10 268 408 6.9E-67 T 09-03-2017 ARZXY2_RS08170 c49589e68f83fa25fa1f42dac93d3fac 409 SUPERFAMILY SSF55973 17 122 9.03E-44 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 285 3.4E-49 T 09-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 9 283 36.117 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 31 279 6.2E-65 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 Pfam PF05175 Methyltransferase small domain 86 197 2.8E-12 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 Gene3D G3DSA:3.40.50.150 92 282 1.3E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 SUPERFAMILY SSF53335 9 279 9.67E-49 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05195 a85d44e08b7f7a3abeea32816fa076e8 290 Gene3D G3DSA:1.10.8.10 8 90 1.9E-17 T 09-03-2017 ARZXY2_RS10560 617444ac34f1c74b0aa59ff34501bcc0 165 Pfam PF11292 Protein of unknown function (DUF3093) 14 151 2.0E-45 T 09-03-2017 IPR021443 Protein of unknown function DUF3093 ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 7 183 5.7E-65 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 Gene3D G3DSA:3.40.50.300 4 27 9.5E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 Gene3D G3DSA:3.40.50.300 88 183 9.5E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 09-03-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 Gene3D G3DSA:3.30.63.10 35 87 1.9E-25 T 09-03-2017 ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 Pfam PF00625 Guanylate kinase 8 183 8.2E-39 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 SUPERFAMILY SSF52540 7 183 1.73E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 34.658 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 ARZXY2_RS08155 619ad59760dddceba2e7d4b94e7557df 190 SMART SM00072 4 187 3.8E-56 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS04400 102da62b2b0d665585250a68dbee87f6 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS18700 102da62b2b0d665585250a68dbee87f6 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Gene3D G3DSA:3.40.120.10 174 256 6.5E-30 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 1.3E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 211 224 1.3E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.3E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 1.3E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 384 463 2.4E-12 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 SUPERFAMILY SSF53738 155 262 1.96E-28 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 269 376 5.5E-24 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 SUPERFAMILY SSF53738 5 123 7.85E-27 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 131 6.0E-27 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Gene3D G3DSA:3.40.120.10 257 379 1.3E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Gene3D G3DSA:3.40.120.10 5 122 5.4E-25 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 260 1.8E-22 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 Gene3D G3DSA:3.30.310.50 381 463 4.9E-18 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 SUPERFAMILY SSF53738 279 374 2.75E-26 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS10110 79fd3b74628adacf12c22a79a7f28c04 464 SUPERFAMILY SSF55957 378 464 1.03E-15 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS02040 45f010da8560b543d8e32e2a84a5c9b6 306 Gene3D G3DSA:1.10.3720.10 29 293 1.5E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02040 45f010da8560b543d8e32e2a84a5c9b6 306 SUPERFAMILY SSF161098 30 306 1.87E-72 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02040 45f010da8560b543d8e32e2a84a5c9b6 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 299 1.4E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS00705 31f88ca22ad4773803a6b7d6df32add3 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 1.0E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS00705 31f88ca22ad4773803a6b7d6df32add3 237 Gene3D G3DSA:1.10.357.10 8 231 8.6E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS00705 31f88ca22ad4773803a6b7d6df32add3 237 SUPERFAMILY SSF46689 10 84 1.95E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS00705 31f88ca22ad4773803a6b7d6df32add3 237 SUPERFAMILY SSF48498 95 231 1.67E-26 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS13475 45ec28f168490367dd15a42c6a32f2fa 416 PIRSF PIRSF006060 2 414 4.3E-64 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS13475 45ec28f168490367dd15a42c6a32f2fa 416 Pfam PF13520 Amino acid permease 11 385 3.5E-42 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 PIRSF PIRSF001456 1 385 2.0E-125 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 SUPERFAMILY SSF103263 2 390 1.44E-138 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 Gene3D G3DSA:3.60.150.10 1 391 2.8E-151 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 ProSitePatterns PS00789 Chorismate synthase signature 3. 342 358 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 TIGRFAM TIGR00033 aroC: chorismate synthase 2 373 1.9E-129 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 Pfam PF01264 Chorismate synthase 2 368 2.6E-117 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 Hamap MF_00300 Chorismate synthase [aroC]. 2 375 33.715 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS08080 86d33e8d791b1aade8f4023759ee5740 399 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 449 1.2E-30 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Gene3D G3DSA:2.40.110.10 176 280 3.6E-33 T 09-03-2017 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Gene3D G3DSA:1.10.540.10 37 174 1.3E-26 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 SUPERFAMILY SSF47203 291 450 3.06E-34 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 279 1.1E-21 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 67 172 1.2E-19 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 SUPERFAMILY SSF56645 85 304 8.51E-59 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS20540 d3a0af51cc452c8d1f31f6b5617a2f43 654 Gene3D G3DSA:1.20.140.10 281 452 5.2E-47 T 09-03-2017 ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.9E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.9E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 Gene3D G3DSA:1.20.120.530 89 228 1.1E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 SUPERFAMILY SSF46785 19 108 2.56E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 SUPERFAMILY SSF48008 91 224 6.54E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 Pfam PF07729 FCD domain 95 217 4.5E-20 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 Gene3D G3DSA:1.10.10.10 18 86 6.4E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 SMART SM00895 95 218 2.6E-15 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 SMART SM00345 27 85 4.3E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14785 cc644039b21e3582b7cebb22970f6998 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 85 2.8E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS09645 3734ffb6f13ee952321c6e263ade1276 364 Pfam PF01212 Beta-eliminating lyase 13 295 8.5E-79 T 09-03-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 ARZXY2_RS09645 3734ffb6f13ee952321c6e263ade1276 364 SUPERFAMILY SSF53383 12 353 3.3E-102 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS09645 3734ffb6f13ee952321c6e263ade1276 364 Gene3D G3DSA:3.90.1150.10 258 352 1.6E-24 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS09645 3734ffb6f13ee952321c6e263ade1276 364 Gene3D G3DSA:3.40.640.10 12 257 3.2E-65 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS09645 3734ffb6f13ee952321c6e263ade1276 364 PIRSF PIRSF017617 6 363 3.7E-118 T 09-03-2017 IPR023603 Threonine aldolase ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Gene3D G3DSA:3.10.150.10 124 248 3.8E-31 T 09-03-2017 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 SUPERFAMILY SSF55979 126 243 3.02E-23 T 09-03-2017 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 2.9E-32 T 09-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 244 1.7E-27 T 09-03-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 SMART SM00480 17 368 6.1E-110 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 SUPERFAMILY SSF55979 246 372 1.1E-29 T 09-03-2017 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 372 7.4E-89 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 PIRSF PIRSF000804 1 373 1.2E-97 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Gene3D G3DSA:3.10.150.10 2 120 1.5E-30 T 09-03-2017 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 370 6.3E-29 T 09-03-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 Gene3D G3DSA:3.10.150.10 250 373 1.5E-39 T 09-03-2017 ARZXY2_RS18565 f4feeac1123dce278933c2a8990e34d9 374 SUPERFAMILY SSF55979 2 119 4.32E-24 T 09-03-2017 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Pfam PF00013 KH domain 590 647 7.9E-11 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 274 348 3.2E-18 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 726 0.0 T 09-03-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF54211 7 152 6.07E-44 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SMART SM00322 584 649 3.6E-11 T 09-03-2017 IPR004087 K Homology domain GO:0003676 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Pfam PF01138 3' exoribonuclease family, domain 1 353 485 8.8E-15 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 2.0E-15 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF55666 153 265 1.48E-24 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Gene3D G3DSA:3.30.1370.10 584 656 3.7E-24 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF50249 652 726 2.22E-15 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF55666 480 578 2.32E-23 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SMART SM00316 654 728 2.9E-19 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 731 27.005 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Gene3D G3DSA:3.30.230.70 8 253 4.3E-80 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Gene3D G3DSA:3.30.230.70 341 575 8.6E-80 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF54211 325 497 2.58E-43 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 726 9.5E-259 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 PIRSF PIRSF005499 8 749 4.5E-282 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Pfam PF00575 S1 RNA binding domain 653 726 1.2E-14 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF54791 587 673 5.69E-19 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Gene3D G3DSA:2.40.50.140 657 726 6.9E-20 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 SUPERFAMILY SSF46915 270 350 1.39E-19 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS11505 109c0facb1628248836761f4f3e84a22 749 Gene3D G3DSA:1.10.10.400 268 340 1.1E-25 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 Pfam PF01614 Bacterial transcriptional regulator 136 256 1.1E-13 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 SUPERFAMILY SSF46785 18 84 4.05E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 SUPERFAMILY SSF55781 74 261 6.38E-36 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 Pfam PF09339 IclR helix-turn-helix domain 18 68 2.2E-14 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 SMART SM00346 16 106 1.7E-25 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 Gene3D G3DSA:3.30.450.40 85 262 2.6E-38 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00695 7beb294bd337d3b09d5f2c4a15d3d934 267 Gene3D G3DSA:1.10.10.10 13 84 4.7E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 PIRSF PIRSF001423 3 573 6.2E-269 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 Gene3D G3DSA:3.40.50.10730 143 364 5.9E-81 T 09-03-2017 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 Gene3D G3DSA:3.40.1770.10 375 569 4.8E-155 T 09-03-2017 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 Gene3D G3DSA:3.40.1770.10 11 142 4.8E-155 T 09-03-2017 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 Pfam PF01175 Urocanase 13 562 2.9E-249 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 TIGRFAM TIGR01228 hutU: urocanate hydratase 13 569 8.3E-263 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 Hamap MF_00577 Urocanate hydratase [hutU]. 8 571 49.457 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 SUPERFAMILY SSF111326 10 570 6.8E-242 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16790 733a67abd4f519eec60613326c791018 573 ProSitePatterns PS01233 Urocanase signature. 457 472 - T 09-03-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS04965 3c949f806b78f33f297f8c2770382017 471 SUPERFAMILY SSF57997 40 138 1.34E-5 T 09-03-2017 ARZXY2_RS04965 3c949f806b78f33f297f8c2770382017 471 Pfam PF01551 Peptidase family M23 367 467 4.1E-27 T 09-03-2017 IPR016047 Peptidase M23 ARZXY2_RS04965 3c949f806b78f33f297f8c2770382017 471 SUPERFAMILY SSF51261 263 471 1.99E-47 T 09-03-2017 IPR011055 Duplicated hybrid motif ARZXY2_RS04965 3c949f806b78f33f297f8c2770382017 471 Gene3D G3DSA:2.70.70.10 325 471 2.5E-40 T 09-03-2017 ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 Gene3D G3DSA:3.90.226.10 3 260 8.8E-81 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 Gene3D G3DSA:3.90.226.10 274 527 4.6E-97 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 4.5E-5 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 4.5E-5 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 SUPERFAMILY SSF52096 11 261 3.84E-78 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 SUPERFAMILY SSF52096 248 527 6.55E-87 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS12480 bbdef678c57ab60d3e36507e9df7e992 527 Pfam PF01039 Carboxyl transferase domain 33 525 4.9E-192 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18535 5e6ecd2b2566492d94671c98434c8b00 222 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 104 221 3.3E-41 T 09-03-2017 IPR021949 Domain of unknown function DUF3566. transmembrane ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 SUPERFAMILY SSF52518 375 591 5.89E-21 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 ProSitePatterns PS60002 Phosphoketolase signature 1. 143 149 - T 09-03-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 Pfam PF09364 XFP N-terminal domain 9 382 2.9E-161 T 09-03-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 PIRSF PIRSF017245 1 795 0.0 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 575 7.1E-76 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 Pfam PF09363 XFP C-terminal domain 586 793 2.4E-78 T 09-03-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 SUPERFAMILY SSF52518 8 365 1.29E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 ProSitePatterns PS60003 Phosphoketolase signature 2. 156 174 - T 09-03-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 ARZXY2_RS09795 8d0ea5e85851ac30d046dcb9d2d6f138 798 Gene3D G3DSA:3.40.50.970 7 265 1.4E-22 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 Gene3D G3DSA:3.30.70.360 194 309 2.1E-33 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 Gene3D G3DSA:3.40.630.10 310 403 4.4E-80 T 09-03-2017 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 Gene3D G3DSA:3.40.630.10 8 190 4.4E-80 T 09-03-2017 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 Pfam PF07687 Peptidase dimerisation domain 199 290 3.9E-11 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 PIRSF PIRSF005962 6 406 1.9E-92 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 SUPERFAMILY SSF53187 310 402 1.19E-67 T 09-03-2017 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 SUPERFAMILY SSF53187 11 209 1.19E-67 T 09-03-2017 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 387 3.5E-80 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 Pfam PF01546 Peptidase family M20/M25/M40 82 397 4.1E-25 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS07130 f1131c0a5234b5fe0e1eff41eb1bf518 409 SUPERFAMILY SSF55031 198 308 4.32E-27 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 SUPERFAMILY SSF48264 28 363 5.63E-41 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 Gene3D G3DSA:1.10.630.10 22 363 1.4E-43 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 Pfam PF00067 Cytochrome P450 270 364 4.7E-9 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 PRINTS PR00463 E-class P450 group I signature 225 242 5.5E-5 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 PRINTS PR00463 E-class P450 group I signature 342 365 5.5E-5 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 PRINTS PR00463 E-class P450 group I signature 332 342 5.5E-5 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 PRINTS PR00463 E-class P450 group I signature 269 287 5.5E-5 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS03610 f0013418be9faaeb5cb80a7bd41a2080 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 Pfam PF01494 FAD binding domain 2 340 3.4E-69 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 326 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 6.5E-38 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 Gene3D G3DSA:3.50.50.60 273 313 1.7E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 Gene3D G3DSA:3.50.50.60 3 164 1.7E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 Gene3D G3DSA:3.30.9.10 165 268 1.5E-14 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 Gene3D G3DSA:3.30.9.10 323 353 1.5E-14 T 09-03-2017 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 SUPERFAMILY SSF51905 3 174 4.63E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17090 ba8a8c80fa1d597d5fee93ab519f8737 536 SUPERFAMILY SSF51905 262 376 4.63E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14650 9ff63ef58a30eb2edd98996f172afe66 512 Pfam PF13520 Amino acid permease 28 457 1.4E-27 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS14650 9ff63ef58a30eb2edd98996f172afe66 512 PIRSF PIRSF006060 7 494 6.9E-51 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 09-03-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 PRINTS PR00342 Rhesus blood group protein signature 263 276 9.1E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 PRINTS PR00342 Rhesus blood group protein signature 96 112 9.1E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 PRINTS PR00342 Rhesus blood group protein signature 200 218 9.1E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 TIGRFAM TIGR00836 amt: ammonium transporter 8 403 9.4E-117 T 09-03-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 Pfam PF00909 Ammonium Transporter Family 8 403 1.2E-108 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 Gene3D G3DSA:1.10.3430.10 5 384 6.1E-115 T 09-03-2017 IPR029020 Ammonium/urea transporter ARZXY2_RS01515 5ef8923e7c482f04dd5293eec9390a6b 442 SUPERFAMILY SSF111352 7 384 8.24E-104 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 Pfam PF00561 alpha/beta hydrolase fold 38 271 2.6E-21 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 8.3E-10 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 8.3E-10 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 8.3E-10 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 Gene3D G3DSA:3.40.50.1820 18 284 1.2E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19080 437f6d88ba563538b8b2ada563510279 286 SUPERFAMILY SSF53474 12 284 5.8E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Gene3D G3DSA:1.10.3120.10 212 384 7.1E-37 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Hamap MF_00303 Trigger factor [tig]. 1 414 17.289 T 09-03-2017 IPR005215 Trigger factor GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Gene3D G3DSA:3.30.70.1050 3 123 7.7E-32 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 SUPERFAMILY SSF109998 248 426 3.4E-36 T 09-03-2017 IPR027304 Trigger factor/SurA domain ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Gene3D G3DSA:3.10.50.40 161 211 6.2E-5 T 09-03-2017 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 PIRSF PIRSF003095 1 424 3.6E-104 T 09-03-2017 IPR005215 Trigger factor GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 TIGRFAM TIGR00115 tig: trigger factor 12 407 2.8E-107 T 09-03-2017 IPR005215 Trigger factor GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 260 408 1.7E-24 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 SUPERFAMILY SSF102735 3 134 1.57E-33 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 SUPERFAMILY SSF54534 138 246 1.61E-17 T 09-03-2017 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Pfam PF05697 Bacterial trigger factor protein (TF) 3 149 9.9E-40 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 ARZXY2_RS07585 ce5c7b321dace510b76f30fbdd2f72a5 458 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 162 216 1.9E-4 T 09-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 ARZXY2_RS04880 af227f4a3c76338eed3fb13a34d415a2 161 Pfam PF04138 GtrA-like protein 15 128 1.5E-16 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ARZXY2_RS17325 b182d320fe125c0aca9344b83307186d 277 Gene3D G3DSA:1.10.3720.10 8 264 3.5E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17325 b182d320fe125c0aca9344b83307186d 277 SUPERFAMILY SSF161098 9 277 2.71E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17325 b182d320fe125c0aca9344b83307186d 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 271 7.3E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13005 2193c974f25cbf809d1f0cdd99e2353d 300 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 10 299 3.0E-140 T 09-03-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 ARZXY2_RS13005 2193c974f25cbf809d1f0cdd99e2353d 300 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 13 300 49.415 T 09-03-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 ARZXY2_RS13005 2193c974f25cbf809d1f0cdd99e2353d 300 Gene3D G3DSA:3.40.50.10320 8 300 8.2E-82 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS13005 2193c974f25cbf809d1f0cdd99e2353d 300 SUPERFAMILY SSF102588 9 299 2.22E-72 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS13005 2193c974f25cbf809d1f0cdd99e2353d 300 Pfam PF02585 GlcNAc-PI de-N-acetylase 13 160 4.3E-24 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 SUPERFAMILY SSF46894 140 209 2.21E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.1E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 Pfam PF00072 Response regulator receiver domain 1 113 2.0E-15 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 SMART SM00421 147 204 7.5E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 SUPERFAMILY SSF52172 1 131 2.42E-21 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.5E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.5E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.5E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 Gene3D G3DSA:3.40.50.2300 1 118 5.3E-23 T 09-03-2017 ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 Gene3D G3DSA:1.10.10.10 119 210 9.6E-36 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03385 94bec5d4f0cff8e6ad28857d824b9bb5 210 SMART SM00448 1 113 6.3E-11 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS15235 b7879fd506227f7b29f63c8bbd9221f0 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 42.238 T 09-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ARZXY2_RS15235 b7879fd506227f7b29f63c8bbd9221f0 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 5 208 2.0E-76 T 09-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ARZXY2_RS15235 b7879fd506227f7b29f63c8bbd9221f0 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 208 1.1E-63 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS15235 b7879fd506227f7b29f63c8bbd9221f0 211 SUPERFAMILY SSF53271 4 208 1.26E-63 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS15235 b7879fd506227f7b29f63c8bbd9221f0 211 Gene3D G3DSA:3.40.50.2020 3 208 3.4E-72 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS19280 95ceea24734490edb279ce192fb71153 181 Gene3D G3DSA:3.30.460.10 2 163 1.5E-43 T 09-03-2017 ARZXY2_RS19280 95ceea24734490edb279ce192fb71153 181 SUPERFAMILY SSF81301 5 162 1.44E-38 T 09-03-2017 ARZXY2_RS19280 95ceea24734490edb279ce192fb71153 181 Pfam PF04229 GrpB protein 2 161 4.6E-42 T 09-03-2017 IPR007344 GrpB/Dephospho-CoA kinase ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 2.6E-29 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 SUPERFAMILY SSF51735 138 311 3.25E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 Pfam PF00107 Zinc-binding dehydrogenase 175 304 4.6E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 Gene3D G3DSA:3.40.50.720 169 288 4.8E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 SMART SM00829 8 341 3.8E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 Gene3D G3DSA:3.90.180.10 2 168 2.4E-53 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS00610 a92850e94b9c2161df7e543e0b7040ea 345 SUPERFAMILY SSF50129 2 169 3.2E-47 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 89 100 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 352 363 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 153 168 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 294 321 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 136 152 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 343 352 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 277 288 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00359 B-class P450 signature 322 337 1.4E-33 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 Pfam PF00067 Cytochrome P450 172 371 1.2E-28 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00385 P450 superfamily signature 242 259 5.6E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00385 P450 superfamily signature 352 363 5.6E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 PRINTS PR00385 P450 superfamily signature 343 352 5.6E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 SUPERFAMILY SSF48264 45 389 3.93E-85 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS07180 a23503317ce44d65597edeeed018ee2d 397 Gene3D G3DSA:1.10.630.10 23 386 2.4E-99 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 ARZXY2_RS01925 30370dc4ca42d9e981a917ed715db7cf 477 Pfam PF02386 Cation transport protein 69 455 4.4E-45 T 09-03-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 ARZXY2_RS11340 43e9c167ae3c517cbbae32591853f35b 118 SUPERFAMILY SSF54106 67 116 4.32E-5 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS11340 43e9c167ae3c517cbbae32591853f35b 118 Pfam PF01476 LysM domain 69 116 9.9E-9 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS11340 43e9c167ae3c517cbbae32591853f35b 118 Gene3D G3DSA:3.10.350.10 69 116 6.2E-9 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS11340 43e9c167ae3c517cbbae32591853f35b 118 SMART SM00257 67 116 5.4E-6 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PRINTS PR00471 Acetate kinase family signature 181 202 3.0E-31 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PRINTS PR00471 Acetate kinase family signature 151 164 3.0E-31 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PRINTS PR00471 Acetate kinase family signature 276 289 3.0E-31 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PRINTS PR00471 Acetate kinase family signature 3 14 3.0E-31 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PRINTS PR00471 Acetate kinase family signature 298 314 3.0E-31 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 Hamap MF_00020 Acetate kinase [ackA]. 1 381 131.516 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 TIGRFAM TIGR00016 ackA: acetate kinase 2 377 4.5E-105 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 Gene3D G3DSA:3.30.420.40 183 377 2.2E-67 T 09-03-2017 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 PIRSF PIRSF000722 46 382 5.7E-106 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 Pfam PF00871 Acetokinase family 3 372 6.7E-104 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 SUPERFAMILY SSF53067 1 170 1.12E-45 T 09-03-2017 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 SUPERFAMILY SSF53067 135 378 2.82E-71 T 09-03-2017 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 Gene3D G3DSA:3.30.420.40 1 182 2.5E-10 T 09-03-2017 ARZXY2_RS09800 dfa8dfe9b7a8bb6743c375dd9503a12c 383 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 181 198 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 Gene3D G3DSA:1.20.1560.10 7 321 7.5E-63 T 09-03-2017 ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 Pfam PF00005 ABC transporter 351 498 2.5E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 SUPERFAMILY SSF52540 326 570 1.64E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 Pfam PF00664 ABC transporter transmembrane region 18 285 9.5E-42 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 Gene3D G3DSA:3.40.50.300 334 561 1.0E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 SMART SM00382 360 552 1.3E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13965 07414136a393cd630c867a3c21b0720a 577 SUPERFAMILY SSF90123 6 316 3.53E-70 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 SMART SM00354 1 72 6.1E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 Gene3D G3DSA:3.40.50.2300 55 173 3.0E-33 T 09-03-2017 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 09-03-2017 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 49 5.0E-18 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 Gene3D G3DSA:1.10.260.40 1 54 1.2E-24 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 SUPERFAMILY SSF53822 62 329 3.53E-63 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 70 299 3.0E-31 T 09-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 SUPERFAMILY SSF47413 1 57 1.9E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15990 c6a6208a76b3daa66a21d7706a48e98a 334 Gene3D G3DSA:3.40.50.2300 174 306 2.0E-47 T 09-03-2017 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 Pfam PF01144 Coenzyme A transferase 37 235 5.4E-47 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 33 241 5.4E-100 T 09-03-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 SUPERFAMILY SSF100950 33 244 7.23E-75 T 09-03-2017 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 74 82 - T 09-03-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 Gene3D G3DSA:3.40.810.20 33 241 1.5E-92 T 09-03-2017 ARZXY2_RS11685 9acf21d9a2d59e62fd67aa4069b8acf9 250 SMART SM00882 36 236 5.1E-74 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS08675 3c4181745780d5a93f9a2cac9273ed10 388 SUPERFAMILY SSF54631 268 379 3.54E-6 T 09-03-2017 ARZXY2_RS08675 3c4181745780d5a93f9a2cac9273ed10 388 Pfam PF02163 Peptidase family M50 144 191 5.5E-7 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 ARZXY2_RS08675 3c4181745780d5a93f9a2cac9273ed10 388 PIRSF PIRSF006404 14 386 1.5E-62 T 09-03-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 SUPERFAMILY SSF46785 3 64 4.72E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 SUPERFAMILY SSF53067 73 386 5.28E-52 T 09-03-2017 ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 Pfam PF00480 ROK family 84 385 3.5E-46 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 ProSitePatterns PS01125 ROK family signature. 208 235 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 Gene3D G3DSA:3.30.420.40 213 366 1.4E-40 T 09-03-2017 ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 Gene3D G3DSA:3.30.420.40 71 212 1.3E-41 T 09-03-2017 ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 Gene3D G3DSA:1.10.10.10 8 69 1.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07735 805a897549a82161d32c66865a42a537 399 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 49 1.0E-6 T 09-03-2017 ARZXY2_RS20375 4e867dc2f7db97ba1b06dc52fec5819c 453 SUPERFAMILY SSF103473 27 451 9.02E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20375 4e867dc2f7db97ba1b06dc52fec5819c 453 ProSitePatterns PS00216 Sugar transport proteins signature 1. 318 335 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS20375 4e867dc2f7db97ba1b06dc52fec5819c 453 Gene3D G3DSA:1.20.1250.20 261 449 9.0E-26 T 09-03-2017 ARZXY2_RS20375 4e867dc2f7db97ba1b06dc52fec5819c 453 Gene3D G3DSA:1.20.1250.20 33 242 4.3E-28 T 09-03-2017 ARZXY2_RS20375 4e867dc2f7db97ba1b06dc52fec5819c 453 Pfam PF07690 Major Facilitator Superfamily 43 402 1.6E-36 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS10300 5807e65aa127a06de208e79ad567ea4c 258 Pfam PF00977 Histidine biosynthesis protein 6 238 3.0E-82 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 ARZXY2_RS10300 5807e65aa127a06de208e79ad567ea4c 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 258 9.8E-105 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 ARZXY2_RS10300 5807e65aa127a06de208e79ad567ea4c 258 SUPERFAMILY SSF51366 4 258 3.69E-76 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS10300 5807e65aa127a06de208e79ad567ea4c 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 258 44.526 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 ARZXY2_RS10300 5807e65aa127a06de208e79ad567ea4c 258 Gene3D G3DSA:3.20.20.70 6 258 2.0E-99 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS09060 9e7141f6abcd7e4eeebcbe4db7066786 85 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 6.0E-5 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS09060 9e7141f6abcd7e4eeebcbe4db7066786 85 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 6.0E-5 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS09060 9e7141f6abcd7e4eeebcbe4db7066786 85 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 6.0E-5 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS09060 9e7141f6abcd7e4eeebcbe4db7066786 85 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 4.1E-17 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS09060 9e7141f6abcd7e4eeebcbe4db7066786 85 Pfam PF03840 Preprotein translocase SecG subunit 7 76 1.4E-16 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS06675 c1a6d424d6c80f717787aca254cfd5f8 140 SUPERFAMILY SSF52788 8 132 7.2E-36 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06675 c1a6d424d6c80f717787aca254cfd5f8 140 SMART SM00226 9 134 4.3E-47 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06675 c1a6d424d6c80f717787aca254cfd5f8 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 11 131 9.9E-24 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06675 c1a6d424d6c80f717787aca254cfd5f8 140 Gene3D G3DSA:3.40.50.270 7 132 8.1E-41 T 09-03-2017 ARZXY2_RS00220 85c11d47692a490c4e1b9d8d4d0489d8 298 SUPERFAMILY SSF74650 5 295 5.4E-61 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS00220 85c11d47692a490c4e1b9d8d4d0489d8 298 Gene3D G3DSA:2.70.98.10 4 295 3.6E-43 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS00220 85c11d47692a490c4e1b9d8d4d0489d8 298 Pfam PF01263 Aldose 1-epimerase 5 294 2.4E-43 T 09-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 SUPERFAMILY SSF55620 2 118 6.12E-35 T 09-03-2017 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 Gene3D G3DSA:3.30.1130.10 2 118 4.9E-41 T 09-03-2017 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 1.8E-33 T 09-03-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 Pfam PF02152 Dihydroneopterin aldolase 4 114 4.1E-32 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 1.6E-28 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS17980 1dc6352ed2ff23d8633eeb5699e81e46 119 SMART SM00905 4 116 1.0E-44 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 491 3.3E-41 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Gene3D G3DSA:3.90.960.10 290 410 8.4E-4 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Pfam PF03129 Anticodon binding domain 507 597 8.8E-16 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 SUPERFAMILY SSF55681 439 510 2.84E-88 T 09-03-2017 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 SUPERFAMILY SSF55681 12 238 2.84E-88 T 09-03-2017 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Gene3D G3DSA:3.40.50.800 502 600 3.6E-24 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.7E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 4.7E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.7E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 4.7E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Gene3D G3DSA:3.30.930.10 424 500 1.5E-96 T 09-03-2017 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Gene3D G3DSA:3.30.930.10 8 206 1.5E-96 T 09-03-2017 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 SUPERFAMILY SSF55826 287 410 5.36E-5 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 3 596 8.5E-160 T 09-03-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 SUPERFAMILY SSF52954 496 601 2.62E-27 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Pfam PF04073 Aminoacyl-tRNA editing domain 258 411 8.6E-18 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS11585 05871057281c85f15114922bf77a10f5 603 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 601 36.398 T 09-03-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 ARZXY2_RS04005 e5355faa0d3e43ef0a7bf73f98b830be 568 SUPERFAMILY SSF56112 209 457 7.33E-22 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS04005 e5355faa0d3e43ef0a7bf73f98b830be 568 SUPERFAMILY SSF56112 104 174 7.33E-22 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS04005 e5355faa0d3e43ef0a7bf73f98b830be 568 Gene3D G3DSA:3.90.1200.10 289 338 1.8E-7 T 09-03-2017 ARZXY2_RS04005 e5355faa0d3e43ef0a7bf73f98b830be 568 Pfam PF03109 ABC1 family 122 246 2.3E-26 T 09-03-2017 IPR004147 UbiB domain ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 56 2.7E-11 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 Gene3D G3DSA:1.10.260.40 9 58 2.3E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 SMART SM00354 9 79 4.9E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 Pfam PF13377 Periplasmic binding protein-like domain 173 331 2.2E-35 T 09-03-2017 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 Gene3D G3DSA:3.40.50.2300 180 313 3.7E-41 T 09-03-2017 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 SUPERFAMILY SSF47413 9 65 5.9E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 Gene3D G3DSA:3.40.50.2300 59 179 1.6E-28 T 09-03-2017 ARZXY2_RS12620 e8c3ee801b277e3f4df4e8cc51fc1304 335 SUPERFAMILY SSF53822 70 334 2.17E-56 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 SUPERFAMILY SSF56235 37 598 6.4E-154 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 48 593 9.4E-130 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 272 288 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 416 434 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 163 182 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 145 163 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 440 458 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 473 488 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 68 93 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 497 514 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 302 321 1.4E-69 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS01355 7694acb290a6a3de6d090bfbc06b4b0d 621 Pfam PF01019 Gamma-glutamyltranspeptidase 61 597 3.1E-153 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 ARZXY2_RS19420 39b5cf238ca2f5553a38c7f009a57608 186 SUPERFAMILY SSF50199 48 183 5.62E-31 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS19420 39b5cf238ca2f5553a38c7f009a57608 186 Pfam PF00565 Staphylococcal nuclease homologue 75 183 1.9E-14 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS19420 39b5cf238ca2f5553a38c7f009a57608 186 SMART SM00318 49 184 1.2E-17 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS19420 39b5cf238ca2f5553a38c7f009a57608 186 Gene3D G3DSA:2.40.50.90 49 153 1.3E-25 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS11830 1d2d7c2b5959f32a40221eae7de096ba 416 Pfam PF00589 Phage integrase family 166 358 2.9E-18 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS11830 1d2d7c2b5959f32a40221eae7de096ba 416 SUPERFAMILY SSF56349 61 365 2.06E-55 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS11830 1d2d7c2b5959f32a40221eae7de096ba 416 Gene3D G3DSA:1.10.150.130 62 158 7.2E-15 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS11830 1d2d7c2b5959f32a40221eae7de096ba 416 Gene3D G3DSA:1.10.443.10 165 364 2.0E-37 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS11830 1d2d7c2b5959f32a40221eae7de096ba 416 ProSitePatterns PS00221 MIP family signature. 344 352 - T 09-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS19085 597b8cc85e780000a67fb442d4316af3 264 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 89 232 1.3E-7 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS19085 597b8cc85e780000a67fb442d4316af3 264 Gene3D G3DSA:3.90.850.10 2 258 2.4E-63 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS19085 597b8cc85e780000a67fb442d4316af3 264 SUPERFAMILY SSF56529 4 254 8.77E-57 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 Pfam PF01966 HD domain 78 229 9.0E-18 T 09-03-2017 IPR006674 HD domain ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 Gene3D G3DSA:1.10.3410.10 227 356 1.5E-19 T 09-03-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 17 431 30.288 T 09-03-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 41 431 1.5E-84 T 09-03-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 SUPERFAMILY SSF109604 32 178 4.87E-56 T 09-03-2017 ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 SUPERFAMILY SSF109604 211 255 4.87E-56 T 09-03-2017 ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 Pfam PF13286 Phosphohydrolase-associated domain 338 429 1.7E-20 T 09-03-2017 IPR026875 Phosphohydrolase-associated domain ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 Gene3D G3DSA:1.10.3210.10 27 226 2.2E-67 T 09-03-2017 IPR006674 HD domain ARZXY2_RS12180 d02e86a334518035e6c5fd73cef9b8e0 438 SMART SM00471 74 240 8.8E-13 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 Gene3D G3DSA:1.10.10.10 19 90 7.5E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 SMART SM00346 20 109 3.9E-24 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 SUPERFAMILY SSF55781 77 266 1.57E-49 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 Gene3D G3DSA:3.30.450.40 92 267 9.3E-55 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 SUPERFAMILY SSF46785 20 89 2.56E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 Pfam PF01614 Bacterial transcriptional regulator 139 261 2.0E-33 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS16490 f8c209768bd404b79c7f2951d8425a06 268 Pfam PF09339 IclR helix-turn-helix domain 22 71 1.2E-15 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS11840 cde39f9e7c71a668f769ff0b863b6071 91 SMART SM00530 8 64 1.8E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS11840 cde39f9e7c71a668f769ff0b863b6071 91 Gene3D G3DSA:1.10.260.40 7 76 1.4E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11840 cde39f9e7c71a668f769ff0b863b6071 91 SUPERFAMILY SSF47413 6 70 1.07E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11840 cde39f9e7c71a668f769ff0b863b6071 91 Pfam PF13560 Helix-turn-helix domain 9 49 3.5E-6 T 09-03-2017 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 ProSitePatterns PS01155 Endonuclease III family signature. 112 141 - T 09-03-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 SMART SM00525 196 216 1.3E-6 T 09-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Gene3D G3DSA:1.10.340.30 33 132 1.8E-33 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 197 213 1.8E-5 T 09-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 SMART SM00478 48 195 2.6E-54 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 197 213 - T 09-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Pfam PF00633 Helix-hairpin-helix motif 109 136 1.3E-7 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 179 1.6E-19 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 TIGRFAM TIGR01083 nth: endonuclease III 14 204 2.2E-74 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Hamap MF_00942 Endonuclease III [nth]. 10 219 36.723 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 SUPERFAMILY SSF48150 13 219 2.51E-66 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS01800 473b6029bc9569c73135c6fbafebaeb9 267 Gene3D G3DSA:1.10.1670.10 133 218 3.5E-32 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 SUPERFAMILY SSF75304 4 487 1.57E-152 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 ProSitePatterns PS00571 Amidases signature. 157 188 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 20 488 8.6E-181 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 Gene3D G3DSA:3.90.1300.10 3 490 3.7E-168 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 16 488 88.507 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS12350 6239b91b999015e3617db71fac5e57fb 518 Pfam PF01425 Amidase 29 476 1.1E-149 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 SUPERFAMILY SSF56420 2 161 3.01E-54 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 Pfam PF01327 Polypeptide deformylase 5 150 3.5E-45 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 8 152 4.4E-37 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 Hamap MF_00163 Peptide deformylase [def]. 2 160 27.868 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 Gene3D G3DSA:3.90.45.10 5 167 2.2E-58 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 PIRSF PIRSF004749 1 175 1.1E-46 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 PRINTS PR01576 Peptide deformylase signature 118 147 6.3E-33 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 PRINTS PR01576 Peptide deformylase signature 33 62 6.3E-33 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 PRINTS PR01576 Peptide deformylase signature 87 98 6.3E-33 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS10360 4dc5e330f588396bd2bc3e9a8cfeeb07 190 PRINTS PR01576 Peptide deformylase signature 99 117 6.3E-33 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Gene3D G3DSA:3.40.50.300 553 650 1.4E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Gene3D G3DSA:3.40.50.300 208 347 1.4E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Pfam PF13361 UvrD-like helicase C-terminal domain 752 818 9.1E-14 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 SUPERFAMILY SSF57783 844 888 8.5E-8 T 09-03-2017 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Gene3D G3DSA:3.40.91.30 381 498 1.2E-4 T 09-03-2017 IPR011578 Restriction endonuclease, FokI, C-terminal/endonuclease I, core GO:0003677|GO:0004536 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Gene3D G3DSA:3.40.50.300 657 833 1.1E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 855 890 1.2E-8 T 09-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Gene3D G3DSA:3.30.65.10 847 888 3.6E-9 T 09-03-2017 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 SUPERFAMILY SSF52540 543 824 1.66E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 SUPERFAMILY SSF52540 208 340 1.66E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Pfam PF00580 UvrD/REP helicase N-terminal domain 210 299 1.8E-16 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS05930 3edca089a351f9d20a3d180c30c47cff 894 Pfam PF00580 UvrD/REP helicase N-terminal domain 510 645 7.4E-16 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 Gene3D G3DSA:3.30.1390.20 10 66 2.2E-22 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 12 66 1.9E-19 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 PIRSF PIRSF002211 1 68 8.0E-26 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 66 17.111 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 Pfam PF00327 Ribosomal protein L30p/L7e 13 62 1.8E-16 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 SUPERFAMILY SSF55129 12 66 2.75E-17 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain ARZXY2_RS03580 9c4c4710779edad7ed866ff1e0838aa8 68 ProSitePatterns PS00634 Ribosomal protein L30 signature. 30 62 - T 09-03-2017 IPR018038 Ribosomal protein L30, conserved site ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 PIRSF PIRSF005650 9 245 6.0E-89 T 09-03-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 12 244 41.81 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 Gene3D G3DSA:3.40.1160.10 9 245 7.7E-84 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 15 244 2.9E-90 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 Pfam PF00696 Amino acid kinase family 16 222 4.7E-29 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS11800 d78ce678d88fc1a6a53ff9786dbabf62 245 SUPERFAMILY SSF53633 14 245 1.7E-67 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS16235 c397d144f6801e9c13d2f28e679cfa06 278 SUPERFAMILY SSF51658 13 256 6.88E-35 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16235 c397d144f6801e9c13d2f28e679cfa06 278 Gene3D G3DSA:3.20.20.150 4 269 8.4E-44 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16235 c397d144f6801e9c13d2f28e679cfa06 278 Pfam PF01261 Xylose isomerase-like TIM barrel 16 197 2.4E-13 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 SMART SM00387 309 412 4.0E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 SUPERFAMILY SSF55874 285 410 4.93E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 Pfam PF07730 Histidine kinase 198 265 1.9E-15 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 411 3.4E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 PIRSF PIRSF037434 1 416 3.2E-123 T 09-03-2017 IPR017205 Signal transduction histidine kinase, ChrS ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 Gene3D G3DSA:3.30.565.10 291 412 8.1E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 9.3E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 9.3E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS18675 21eef1e08e0993de02363ec5e517c54a 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 9.3E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 SUPERFAMILY SSF48008 94 225 3.4E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 SMART SM00895 96 220 2.0E-18 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 67 1.0E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 Gene3D G3DSA:1.10.10.10 3 68 8.7E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 SUPERFAMILY SSF46785 3 71 7.06E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 Gene3D G3DSA:1.20.120.530 93 226 2.5E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 SMART SM00345 9 67 0.0016 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS07415 8c206cd559a802b5de861f77e11b8231 242 Pfam PF07729 FCD domain 97 218 5.6E-22 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1030 1044 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SUPERFAMILY SSF50494 9 128 2.98E-15 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SUPERFAMILY SSF50494 155 195 2.98E-15 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 904 918 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SUPERFAMILY SSF50978 1094 1423 4.52E-69 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:2.130.10.10 929 1157 7.1E-62 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1240 1254 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:3.40.50.300 252 379 7.5E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 778 792 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SUPERFAMILY SSF52540 254 420 1.3E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1323 1337 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF13191 AAA ATPase domain 256 375 6.7E-9 T 09-03-2017 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF13365 Trypsin-like peptidase domain 23 184 5.9E-8 T 09-03-2017 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 838 870 0.05 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1217 1253 5.7E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1258 1293 0.12 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1049 1085 3.0E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 964 1001 1.5E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1176 1211 0.001 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 881 917 3.7E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1299 1336 5.9E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Pfam PF00400 WD domain, G-beta repeat 1096 1126 0.23 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:2.130.10.10 746 928 5.8E-41 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 PRINTS PR00320 G protein beta WD-40 repeat signature 1156 1170 1.9E-5 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 PRINTS PR00320 G protein beta WD-40 repeat signature 1198 1212 1.9E-5 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 PRINTS PR00320 G protein beta WD-40 repeat signature 1030 1044 1.9E-5 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1198 1212 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:2.40.10.10 79 200 8.8E-4 T 09-03-2017 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00382 273 496 0.007 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:2.40.10.10 9 78 3.5E-4 T 09-03-2017 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1072 1086 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1004 1043 0.011 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 837 875 3.3E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1130 1169 0.0013 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1339 1379 130.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1214 1253 2.4E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1172 1211 2.5E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1046 1085 5.9E-8 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1382 1421 290.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 752 791 0.02 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1297 1336 2.2E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 794 834 6.6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1088 1127 0.68 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 962 1001 1.1E-8 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 878 917 9.7E-7 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 920 959 9.1E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SMART SM00320 1256 1294 0.0026 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 946 960 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 Gene3D G3DSA:2.130.10.10 1158 1423 1.6E-58 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 988 1002 - T 09-03-2017 IPR019775 WD40 repeat, conserved site ARZXY2_RS13545 b650fdae265a810f248dcb38b3ab90ec 1431 SUPERFAMILY SSF50978 754 1043 1.21E-68 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 Pfam PF13378 Enolase C-terminal domain-like 101 300 3.3E-36 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 6 293 24.98 T 09-03-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 Gene3D G3DSA:3.20.20.120 99 322 1.3E-56 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 SMART SM00922 88 182 1.2E-19 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 Gene3D G3DSA:3.30.390.10 10 98 2.5E-41 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS02775 49309aafa5624603f33f93e222e2ba68 336 SUPERFAMILY SSF51604 74 293 9.04E-54 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS14010 c6f7dfbde470e00e4cb75b8a7ec00863 278 Pfam PF00413 Matrixin 223 265 6.8E-7 T 09-03-2017 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 ARZXY2_RS14010 c6f7dfbde470e00e4cb75b8a7ec00863 278 Gene3D G3DSA:3.40.390.10 101 267 9.0E-11 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ARZXY2_RS14010 c6f7dfbde470e00e4cb75b8a7ec00863 278 SUPERFAMILY SSF55486 99 266 4.89E-13 T 09-03-2017 ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 9.5E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 SUPERFAMILY SSF48008 82 210 6.8E-30 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 SUPERFAMILY SSF46785 10 102 6.44E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 SMART SM00895 86 206 4.6E-24 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 SMART SM00345 18 76 4.0E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 Gene3D G3DSA:1.10.10.10 6 77 1.5E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 Pfam PF07729 FCD domain 86 204 4.1E-28 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 5.7E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 5.7E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19565 64677efa696479a95bc331573d06e667 229 Gene3D G3DSA:1.20.120.530 80 211 8.1E-30 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 Pfam PF04715 Anthranilate synthase component I, N terminal region 33 173 2.1E-28 T 09-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 32 501 6.7E-179 T 09-03-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 SUPERFAMILY SSF56322 22 501 1.7E-144 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 PRINTS PR00095 Anthranilate synthase component I signature 354 367 4.2E-23 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 PRINTS PR00095 Anthranilate synthase component I signature 340 353 4.2E-23 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 PRINTS PR00095 Anthranilate synthase component I signature 434 448 4.2E-23 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 PRINTS PR00095 Anthranilate synthase component I signature 449 463 4.2E-23 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 Pfam PF00425 chorismate binding enzyme 234 492 4.5E-94 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal ARZXY2_RS10285 513d36091259ad292a3a87b656fa10b5 527 Gene3D G3DSA:3.60.120.10 21 502 1.1E-158 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS11005 7566d9d3bdce74ccac701a76cf9f77eb 422 Pfam PF07690 Major Facilitator Superfamily 8 317 1.7E-37 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS11005 7566d9d3bdce74ccac701a76cf9f77eb 422 SUPERFAMILY SSF103473 5 375 9.68E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS11005 7566d9d3bdce74ccac701a76cf9f77eb 422 Gene3D G3DSA:1.20.1250.20 199 374 5.8E-13 T 09-03-2017 ARZXY2_RS11005 7566d9d3bdce74ccac701a76cf9f77eb 422 Gene3D G3DSA:1.20.1250.20 5 186 2.1E-26 T 09-03-2017 ARZXY2_RS08995 d6d78fc745768afe75d3af090cb8394a 434 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 150 421 2.2E-75 T 09-03-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 ARZXY2_RS08995 d6d78fc745768afe75d3af090cb8394a 434 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 404 3.8E-72 T 09-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 ARZXY2_RS08995 d6d78fc745768afe75d3af090cb8394a 434 SUPERFAMILY SSF101960 85 429 1.96E-87 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 Pfam PF00344 SecY translocase 73 419 5.3E-113 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 Gene3D G3DSA:1.10.3370.10 3 436 4.1E-148 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 181 204 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 268 287 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 404 422 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 155 180 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.2E-101 T 09-03-2017 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 PIRSF PIRSF004557 1 436 5.0E-116 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 SUPERFAMILY SSF103491 2 426 4.84E-120 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 435 28.481 T 09-03-2017 IPR026593 Protein translocase subunit SecY ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 431 2.8E-131 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 09-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03590 e767bffa3baa0c1aca8e04b37d1c056b 436 ProSitePatterns PS00756 Protein secY signature 2. 174 191 - T 09-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03835 89997bad01ce3ffb9567f497cf6bedfc 167 Gene3D G3DSA:3.40.630.30 11 156 8.0E-38 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03835 89997bad01ce3ffb9567f497cf6bedfc 167 Pfam PF00583 Acetyltransferase (GNAT) family 59 134 8.8E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS03835 89997bad01ce3ffb9567f497cf6bedfc 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 152 9.5E-35 T 09-03-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 ARZXY2_RS03835 89997bad01ce3ffb9567f497cf6bedfc 167 SUPERFAMILY SSF55729 12 157 3.43E-34 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 PIRSF PIRSF500136 1 424 1.4E-143 T 09-03-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 SUPERFAMILY SSF48179 206 299 1.02E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 293 5.8E-27 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 186 1.0E-50 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 SUPERFAMILY SSF52413 312 421 5.1E-24 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 413 3.1E-123 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 Gene3D G3DSA:3.40.50.720 3 227 3.9E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 SMART SM00984 317 417 5.3E-25 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 SUPERFAMILY SSF51735 6 200 5.26E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 416 7.9E-21 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 Gene3D G3DSA:3.40.50.720 237 418 8.5E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02615 b9eb67800e8d1a266c2be57987632b09 426 PIRSF PIRSF000124 5 424 8.2E-80 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS12265 9d6819b627a94f96c374e587ebe50ec5 284 SUPERFAMILY SSF51569 8 280 1.13E-79 T 09-03-2017 ARZXY2_RS12265 9d6819b627a94f96c374e587ebe50ec5 284 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 78 90 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS12265 9d6819b627a94f96c374e587ebe50ec5 284 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 282 1.8E-79 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS12265 9d6819b627a94f96c374e587ebe50ec5 284 Gene3D G3DSA:3.20.20.70 8 281 3.9E-83 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS12265 9d6819b627a94f96c374e587ebe50ec5 284 PIRSF PIRSF001359 6 282 5.9E-69 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS06555 64ec11281619b647f4254dc5de220e99 181 SUPERFAMILY SSF54106 133 178 1.22E-8 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS06555 64ec11281619b647f4254dc5de220e99 181 SMART SM00257 134 178 7.3E-8 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS06555 64ec11281619b647f4254dc5de220e99 181 Gene3D G3DSA:3.10.350.10 133 178 1.3E-11 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS06555 64ec11281619b647f4254dc5de220e99 181 Pfam PF01476 LysM domain 135 178 3.3E-7 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS04860 4d825c6e00f9a5a29fcee7983f916b14 670 SUPERFAMILY SSF53448 199 466 2.53E-30 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS04860 4d825c6e00f9a5a29fcee7983f916b14 670 Gene3D G3DSA:3.90.550.10 200 455 5.9E-17 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS04860 4d825c6e00f9a5a29fcee7983f916b14 670 Pfam PF13641 Glycosyltransferase like family 2 201 453 2.1E-43 T 09-03-2017 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 PIRSF PIRSF005917 1 276 1.5E-95 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 273 1.4E-68 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 Gene3D G3DSA:3.40.1010.10 4 112 3.6E-7 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 SUPERFAMILY SSF53790 2 222 1.06E-75 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 1.9E-28 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 Gene3D G3DSA:3.30.950.10 113 225 5.0E-45 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 83 94 - T 09-03-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS12840 fe7b9b8854b1e2d3bf3f6f4d3fda43d3 276 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 224 34.715 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 Pfam PF00375 Sodium:dicarboxylate symporter family 25 402 7.7E-97 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 3.6E-18 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 PRINTS PR00173 Glutamate-aspartate symporter signature 18 43 3.6E-18 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 3.6E-18 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 3.6E-18 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 3.6E-18 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 52 67 - T 09-03-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 Gene3D G3DSA:1.10.3860.10 21 408 1.4E-100 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11060 676acba6a53ec18cddf363102a7d7412 445 SUPERFAMILY SSF118215 25 403 1.44E-99 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SUPERFAMILY SSF55945 204 311 1.37E-16 T 09-03-2017 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SUPERFAMILY SSF57884 2 81 4.45E-31 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SMART SM01009 204 332 2.1E-40 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SMART SM00478 342 495 1.9E-4 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Gene3D G3DSA:1.10.10.60 135 183 5.6E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Pfam PF02805 Metal binding domain of Ada 5 69 4.3E-30 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Gene3D G3DSA:3.30.310.20 204 332 7.6E-27 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Pfam PF12833 Helix-turn-helix domain 104 181 3.7E-16 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 135 177 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SMART SM00342 98 181 1.0E-15 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Gene3D G3DSA:1.10.1670.10 449 493 2.5E-8 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Gene3D G3DSA:3.40.10.10 3 81 3.8E-33 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Gene3D G3DSA:1.10.340.30 335 447 8.5E-27 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SUPERFAMILY SSF46689 135 183 1.12E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 SUPERFAMILY SSF48150 323 492 9.07E-33 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS11185 ebd5c2faa2c2caf9beeb33ee1c6c4d07 497 Pfam PF06029 AlkA N-terminal domain 204 332 6.0E-28 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal ARZXY2_RS11640 af1fc41dec47c694c0a2baff1107e2e9 442 Gene3D G3DSA:3.40.190.10 171 369 7.6E-36 T 09-03-2017 ARZXY2_RS11640 af1fc41dec47c694c0a2baff1107e2e9 442 Gene3D G3DSA:3.40.190.10 52 170 1.3E-19 T 09-03-2017 ARZXY2_RS11640 af1fc41dec47c694c0a2baff1107e2e9 442 Pfam PF01547 Bacterial extracellular solute-binding protein 53 349 6.1E-36 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS11640 af1fc41dec47c694c0a2baff1107e2e9 442 SUPERFAMILY SSF53850 26 440 2.75E-72 T 09-03-2017 ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 SUPERFAMILY SSF46785 26 86 3.0E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 Gene3D G3DSA:3.30.70.920 80 167 1.4E-20 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 SMART SM00344 27 136 2.5E-31 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 Gene3D G3DSA:1.10.10.10 22 78 2.0E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 43 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 54 73 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 54 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 SUPERFAMILY SSF54909 87 166 1.29E-13 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 Pfam PF01037 Lrp/AsnC ligand binding domain 93 166 4.4E-16 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS07220 f8ceff1f20d1b1968e6587bcdd361052 175 Pfam PF13412 Winged helix-turn-helix DNA-binding 27 74 6.3E-14 T 09-03-2017 ARZXY2_RS01275 49394ae2ffedfcb551f278c2d7c586d6 319 Gene3D G3DSA:1.10.3720.10 24 304 9.8E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01275 49394ae2ffedfcb551f278c2d7c586d6 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 303 1.4E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01275 49394ae2ffedfcb551f278c2d7c586d6 319 SUPERFAMILY SSF161098 75 302 1.57E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02940 29550e79473e5cb0058c3a342b1ff62b 480 Pfam PF13556 PucR C-terminal helix-turn-helix domain 413 470 3.1E-23 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS02940 29550e79473e5cb0058c3a342b1ff62b 480 Pfam PF07905 Purine catabolism regulatory protein-like family 11 122 1.4E-27 T 09-03-2017 IPR012914 Purine catabolism PurC-like domain ARZXY2_RS19030 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS17625 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS18405 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS15115 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS07370 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS18400 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS19035 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS10225 ed3910a115fc50fdff4686bbe64e31ef 327 Pfam PF00872 Transposase, Mutator family 61 141 6.1E-12 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 Gene3D G3DSA:3.40.190.10 93 198 1.5E-39 T 09-03-2017 ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 299 1.3E-104 T 09-03-2017 IPR017685 HTH-type transcriptional regulator ArgP ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 Pfam PF03466 LysR substrate binding domain 105 295 9.4E-13 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 SUPERFAMILY SSF46785 4 89 2.85E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 Gene3D G3DSA:1.10.10.10 5 79 3.0E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.8E-16 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS14290 2a256d795f2e2fe3a10bfc85ef103a2d 303 SUPERFAMILY SSF53850 87 297 3.8E-19 T 09-03-2017 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 134 9.3E-22 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 63 75 9.3E-22 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 135 150 9.3E-22 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 21 36 9.3E-22 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 107 122 9.3E-22 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 58 75 - T 09-03-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 175 3.6E-41 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 SUPERFAMILY SSF50891 7 176 1.61E-56 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 PIRSF PIRSF001467 1 179 5.1E-53 T 09-03-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 ARZXY2_RS18500 9d402024ed47e4538376ab3d80749c20 180 Gene3D G3DSA:2.40.100.10 5 177 1.1E-60 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 TIGRFAM TIGR01529 argR_whole: arginine repressor 17 170 2.3E-42 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 Pfam PF02863 Arginine repressor, C-terminal domain 104 167 2.0E-22 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 Gene3D G3DSA:3.30.1360.40 96 170 2.7E-26 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 Gene3D G3DSA:1.10.10.10 12 83 9.5E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 SUPERFAMILY SSF46785 13 81 8.84E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 112 167 2.0E-14 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 Hamap MF_00173 Arginine repressor [argR]. 1 174 56.635 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 SUPERFAMILY SSF55252 103 169 4.45E-17 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 Pfam PF01316 Arginine repressor, DNA binding domain 14 80 9.3E-25 T 09-03-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 PRINTS PR01467 Bacterial arginine repressor signature 110 123 9.8E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 PRINTS PR01467 Bacterial arginine repressor signature 33 46 9.8E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 PRINTS PR01467 Bacterial arginine repressor signature 140 155 9.8E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS11205 1391de9c89add948887a5dd36744972e 178 PRINTS PR01467 Bacterial arginine repressor signature 49 64 9.8E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 22 282 1.0E-76 T 09-03-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 Gene3D G3DSA:3.40.1190.20 20 283 6.5E-95 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 SUPERFAMILY SSF53613 18 285 9.98E-71 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 Gene3D G3DSA:1.20.910.10 292 501 4.9E-60 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 Pfam PF03070 TENA/THI-4/PQQC family 313 501 1.2E-31 T 09-03-2017 IPR004305 Thiaminase-2/PQQC ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 Pfam PF08543 Phosphomethylpyrimidine kinase 29 280 1.2E-75 T 09-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 ARZXY2_RS07665 dcd666dc0d04b5ebc4a2ed4cf6ae5fe4 506 SUPERFAMILY SSF48613 291 501 4.77E-57 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 ARZXY2_RS18825 a8d434ad0f5df7fcc1f568a04424389f 172 SUPERFAMILY SSF53474 3 166 1.32E-12 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS18825 a8d434ad0f5df7fcc1f568a04424389f 172 Gene3D G3DSA:3.40.50.1820 3 168 1.8E-15 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS11405 8f2c7de5af52791956bee6e6d47b5383 169 Pfam PF02464 Competence-damaged protein 12 159 1.6E-49 T 09-03-2017 IPR008136 CinA, C-terminal ARZXY2_RS11405 8f2c7de5af52791956bee6e6d47b5383 169 SUPERFAMILY SSF142433 7 161 1.31E-46 T 09-03-2017 IPR008136 CinA, C-terminal ARZXY2_RS11405 8f2c7de5af52791956bee6e6d47b5383 169 Gene3D G3DSA:3.90.950.20 6 162 3.9E-53 T 09-03-2017 IPR008136 CinA, C-terminal ARZXY2_RS11405 8f2c7de5af52791956bee6e6d47b5383 169 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 22 158 2.3E-38 T 09-03-2017 IPR008136 CinA, C-terminal ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 Gene3D G3DSA:1.20.1250.20 2 135 1.2E-22 T 09-03-2017 ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 Gene3D G3DSA:1.20.1250.20 161 280 6.0E-17 T 09-03-2017 ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 Pfam PF07690 Major Facilitator Superfamily 2 138 2.9E-19 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 Pfam PF07690 Major Facilitator Superfamily 174 280 7.6E-12 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 SUPERFAMILY SSF103473 3 280 6.67E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS23045 63f4db11d64567ac8c40fb4acb81da72 281 ProSitePatterns PS00216 Sugar transport proteins signature 1. 4 20 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 34 331 1.2E-64 T 09-03-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 Gene3D G3DSA:3.30.460.20 3 134 4.5E-42 T 09-03-2017 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 SUPERFAMILY SSF144083 267 329 1.31E-20 T 09-03-2017 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 Gene3D G3DSA:1.20.58.340 135 245 3.7E-37 T 09-03-2017 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 Gene3D G3DSA:1.20.58.340 258 331 2.8E-27 T 09-03-2017 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 Pfam PF01544 CorA-like Mg2+ transporter protein 33 327 2.2E-66 T 09-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 ARZXY2_RS04030 daacfc713ee18b497779e1820b9b30b5 331 SUPERFAMILY SSF143865 6 249 2.09E-65 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.30.70.1400 522 578 2.3E-15 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Pfam PF16350 FAD dependent oxidoreductase central domain 378 433 4.9E-18 T 09-03-2017 IPR032503 FAD dependent oxidoreductase, central domain ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 727 817 1.5E-17 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.30.9.10 86 139 1.2E-61 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.30.9.10 220 338 1.2E-61 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 SUPERFAMILY SSF51905 5 220 1.81E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 SUPERFAMILY SSF51905 339 421 1.81E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:2.40.30.110 743 816 2.6E-26 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.50.50.60 140 219 1.4E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.50.50.60 339 419 1.4E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.50.50.60 1 76 1.4E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 SUPERFAMILY SSF54373 220 338 2.39E-36 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 SUPERFAMILY SSF103025 428 735 1.88E-92 T 09-03-2017 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 SUPERFAMILY SSF101790 744 830 7.36E-24 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Pfam PF01266 FAD dependent oxidoreductase 6 374 9.3E-48 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Pfam PF01571 Aminomethyltransferase folate-binding domain 435 720 5.5E-74 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.30.1360.120 431 521 2.0E-12 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS16455 cbe362d0ce2647f23b91d613d1e855b2 830 Gene3D G3DSA:3.30.1360.120 601 697 2.4E-23 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Pfam PF00580 UvrD/REP helicase N-terminal domain 177 307 2.3E-7 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 SUPERFAMILY SSF52540 382 686 3.6E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 SUPERFAMILY SSF52540 716 753 3.6E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 SUPERFAMILY SSF52540 30 354 3.6E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Pfam PF13361 UvrD-like helicase C-terminal domain 599 739 7.3E-7 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Gene3D G3DSA:3.40.50.300 30 173 3.5E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Gene3D G3DSA:3.40.50.300 215 310 3.5E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Pfam PF12705 PD-(D/E)XK nuclease superfamily 845 1116 2.4E-27 T 09-03-2017 ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Gene3D G3DSA:3.40.50.300 330 469 2.0E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Gene3D G3DSA:3.40.50.300 649 752 2.0E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04535 8bcedd832ac849f092b7f3264515ef28 1126 Pfam PF13245 Part of AAA domain 42 96 3.6E-9 T 09-03-2017 ARZXY2_RS20095 7833668dc8e5a1d651198f0870e3cd9e 327 Gene3D G3DSA:1.10.3720.10 92 315 1.2E-9 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20095 7833668dc8e5a1d651198f0870e3cd9e 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 325 8.2E-31 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20095 7833668dc8e5a1d651198f0870e3cd9e 327 SUPERFAMILY SSF161098 189 306 7.63E-9 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20095 7833668dc8e5a1d651198f0870e3cd9e 327 SUPERFAMILY SSF161098 94 162 7.63E-9 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 SUPERFAMILY SSF51735 955 1057 1.38E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 SUPERFAMILY SSF51735 1095 1224 1.38E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 Gene3D G3DSA:3.40.50.720 952 1063 2.1E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 Gene3D G3DSA:3.40.50.720 1108 1191 2.1E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 PIRSF PIRSF036761 5 1618 0.0 T 09-03-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 SUPERFAMILY SSF53223 766 966 1.34E-24 T 09-03-2017 ARZXY2_RS04815 d3fb8baecae2b968bf76abf6b0478660 1618 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 67 1613 0.0 T 09-03-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 ARZXY2_RS19190 37c3bdc441f3a43cb18e61b4a94b5a44 222 SUPERFAMILY SSF51569 15 210 1.04E-52 T 09-03-2017 ARZXY2_RS19190 37c3bdc441f3a43cb18e61b4a94b5a44 222 Pfam PF01081 KDPG and KHG aldolase 15 186 7.0E-37 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS19190 37c3bdc441f3a43cb18e61b4a94b5a44 222 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 15 208 1.1E-46 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS19190 37c3bdc441f3a43cb18e61b4a94b5a44 222 Gene3D G3DSA:3.20.20.70 16 216 8.4E-62 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS12930 1dbeeedd0e6db36dd6ef8395cc74d2c1 556 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 198 379 8.9E-21 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS12930 1dbeeedd0e6db36dd6ef8395cc74d2c1 556 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 197 379 3.9E-21 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 38 181 1.6E-37 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 2 552 4.2E-275 T 09-03-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Gene3D G3DSA:3.30.310.50 475 552 6.4E-29 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 SUPERFAMILY SSF53738 210 325 2.71E-6 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 SUPERFAMILY SSF53738 24 236 7.3E-49 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 SUPERFAMILY SSF53738 314 456 7.46E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Gene3D G3DSA:3.40.120.10 26 226 4.5E-60 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 329 448 4.9E-28 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 SUPERFAMILY SSF55957 443 552 7.32E-20 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 489 547 1.2E-9 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Gene3D G3DSA:3.40.120.10 227 318 2.7E-43 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Gene3D G3DSA:3.40.120.10 319 454 1.7E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS18195 156fec4c559b9b308b4e655817d3a1ad 553 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 325 3.6E-11 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15600 f1f1444bfb6beba73d7227962e508ae6 397 SUPERFAMILY SSF103473 9 396 8.11E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15600 f1f1444bfb6beba73d7227962e508ae6 397 Gene3D G3DSA:1.20.1250.20 12 193 6.6E-17 T 09-03-2017 ARZXY2_RS15600 f1f1444bfb6beba73d7227962e508ae6 397 Gene3D G3DSA:1.20.1250.20 214 389 1.3E-13 T 09-03-2017 ARZXY2_RS15600 f1f1444bfb6beba73d7227962e508ae6 397 Pfam PF07690 Major Facilitator Superfamily 20 307 4.7E-19 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS12330 1ca702307ab18f59c6be6b3b84630604 262 SUPERFAMILY SSF52540 105 224 1.07E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12330 1ca702307ab18f59c6be6b3b84630604 262 Pfam PF01695 IstB-like ATP binding protein 68 239 2.0E-55 T 09-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 ARZXY2_RS12330 1ca702307ab18f59c6be6b3b84630604 262 SMART SM00382 109 240 6.9E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12330 1ca702307ab18f59c6be6b3b84630604 262 PIRSF PIRSF003073 11 259 4.9E-59 T 09-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein ARZXY2_RS12330 1ca702307ab18f59c6be6b3b84630604 262 Gene3D G3DSA:3.40.50.300 80 240 8.0E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02545 1ca702307ab18f59c6be6b3b84630604 262 SUPERFAMILY SSF52540 105 224 1.07E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02545 1ca702307ab18f59c6be6b3b84630604 262 Pfam PF01695 IstB-like ATP binding protein 68 239 2.0E-55 T 09-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 ARZXY2_RS02545 1ca702307ab18f59c6be6b3b84630604 262 SMART SM00382 109 240 6.9E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02545 1ca702307ab18f59c6be6b3b84630604 262 PIRSF PIRSF003073 11 259 4.9E-59 T 09-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein ARZXY2_RS02545 1ca702307ab18f59c6be6b3b84630604 262 Gene3D G3DSA:3.40.50.300 80 240 8.0E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 SUPERFAMILY SSF51556 128 404 8.51E-58 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 Gene3D G3DSA:3.20.20.140 130 399 4.7E-50 T 09-03-2017 ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 Gene3D G3DSA:2.30.40.10 404 443 1.5E-20 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 Gene3D G3DSA:2.30.40.10 64 129 1.5E-20 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 Pfam PF01979 Amidohydrolase family 124 441 1.7E-24 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 SUPERFAMILY SSF51338 404 435 1.89E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS13670 4edf8021bf3ece5ede5d806f9b57955e 445 SUPERFAMILY SSF51338 65 128 1.89E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 356 362 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 113 125 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 386 398 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 61 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 67 79 1.6E-30 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 419 544 1.6E-30 T 09-03-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 Pfam PF01266 FAD dependent oxidoreductase 39 392 2.3E-46 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 391 401 - T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 SUPERFAMILY SSF51905 39 268 6.6E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 SUPERFAMILY SSF51905 305 367 6.6E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 43 60 - T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 Gene3D G3DSA:3.30.9.10 254 361 3.3E-4 T 09-03-2017 ARZXY2_RS03925 01002fc5fb98911a5cc130a18c08dde8 584 Gene3D G3DSA:3.50.50.60 37 253 4.1E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 SMART SM00382 53 238 5.9E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 Gene3D G3DSA:3.40.50.300 29 261 3.3E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 PIRSF PIRSF039085 25 265 4.5E-97 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 SUPERFAMILY SSF52540 29 260 6.27E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16085 7968693d907f4a4f07568def61074e30 265 Pfam PF00005 ABC transporter 44 190 7.1E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05590 d72f8c6374cb7eb5d1d4fbdf364c51da 157 SUPERFAMILY SSF52833 5 154 1.43E-47 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS05590 d72f8c6374cb7eb5d1d4fbdf364c51da 157 Gene3D G3DSA:3.40.30.10 3 154 6.3E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS05590 d72f8c6374cb7eb5d1d4fbdf364c51da 157 Pfam PF00578 AhpC/TSA family 8 134 5.1E-38 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS05590 d72f8c6374cb7eb5d1d4fbdf364c51da 157 PIRSF PIRSF000239 2 150 2.8E-19 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 Gene3D G3DSA:3.90.930.12 83 177 1.7E-38 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 Pfam PF00347 Ribosomal protein L6 90 164 3.0E-19 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 Pfam PF00347 Ribosomal protein L6 11 82 8.8E-20 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.437 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 SUPERFAMILY SSF56053 1 82 1.96E-26 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 09-03-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 SUPERFAMILY SSF56053 83 176 1.44E-35 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.2E-75 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 9.3E-34 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 9.3E-34 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 9.3E-34 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 PIRSF PIRSF002162 1 177 2.8E-49 T 09-03-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03565 90d80448090d77b89f541dc1347c7301 178 Gene3D G3DSA:3.90.930.12 2 82 1.4E-31 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Gene3D G3DSA:3.40.50.300 25 183 7.9E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 SUPERFAMILY SSF52540 26 246 1.82E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 SUPERFAMILY SSF52540 272 523 6.97E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Pfam PF07724 AAA domain (Cdc48 subfamily) 308 474 6.9E-32 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 SMART SM00382 46 183 0.44 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 SMART SM00382 309 469 1.6E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 51 166 9.8E-7 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Gene3D G3DSA:1.10.8.60 185 248 2.4E-4 T 09-03-2017 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 409 423 3.1E-11 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 313 331 3.1E-11 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Gene3D G3DSA:3.40.50.300 463 499 4.1E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06805 5e380df112fdb5522c6c6da0e648c3ec 588 Gene3D G3DSA:3.40.50.300 273 424 4.1E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 SUPERFAMILY SSF56014 428 573 1.83E-29 T 09-03-2017 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 103 167 7.1E-18 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 352 416 7.6E-14 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 177 331 1.1E-33 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 429 560 7.6E-12 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 SUPERFAMILY SSF55124 27 176 6.05E-37 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Gene3D G3DSA:3.30.413.10 427 573 3.2E-32 T 09-03-2017 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 480 496 - T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Gene3D G3DSA:3.90.480.10 105 174 8.0E-48 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Gene3D G3DSA:3.90.480.10 345 421 8.0E-48 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 SUPERFAMILY SSF55124 309 440 3.43E-20 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 SUPERFAMILY SSF56014 177 337 6.02E-43 T 09-03-2017 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 PRINTS PR00397 Sirohaem Fe-binding site signature 480 498 2.8E-9 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 2.8E-9 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS02845 af96321066b746c6e881cec9d1e4b2db 578 Gene3D G3DSA:3.30.413.10 177 334 3.3E-40 T 09-03-2017 ARZXY2_RS20190 e3480cda96e7645becd9d063554d98bd 139 SUPERFAMILY SSF46955 70 123 1.01E-7 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS20190 e3480cda96e7645becd9d063554d98bd 139 Gene3D G3DSA:1.10.10.10 70 122 1.1E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20190 e3480cda96e7645becd9d063554d98bd 139 Pfam PF12728 Helix-turn-helix domain 70 119 3.0E-13 T 09-03-2017 ARZXY2_RS20190 e3480cda96e7645becd9d063554d98bd 139 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 71 118 9.5E-12 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 SUPERFAMILY SSF89550 4 76 1.39E-7 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 Gene3D G3DSA:2.40.50.140 1049 1126 2.0E-4 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 335 781 4.5E-114 T 09-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 SMART SM00481 4 71 3.7E-11 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 1092 6.1E-151 T 09-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 Gene3D G3DSA:3.20.20.140 3 88 1.6E-7 T 09-03-2017 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 Pfam PF02811 PHP domain 5 111 8.5E-15 T 09-03-2017 IPR004013 PHP domain GO:0003824 ARZXY2_RS07915 a5bf389ae46011ae85e62a16c733e44c 1175 Pfam PF14579 Helix-hairpin-helix motif 868 955 1.9E-18 T 09-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS02875 bc02040a6f6e8b4015bd11671d18cd11 243 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02875 bc02040a6f6e8b4015bd11671d18cd11 243 Pfam PF00005 ABC transporter 19 154 1.8E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02875 bc02040a6f6e8b4015bd11671d18cd11 243 SUPERFAMILY SSF52540 3 213 1.24E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02875 bc02040a6f6e8b4015bd11671d18cd11 243 Gene3D G3DSA:3.40.50.300 4 214 1.9E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02875 bc02040a6f6e8b4015bd11671d18cd11 243 SMART SM00382 28 204 1.4E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02160 b73c98dd6b4c5492cfcf04337252908a 565 Pfam PF05140 ResB-like family 49 532 9.0E-128 T 09-03-2017 IPR007816 ResB-like domain ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 Gene3D G3DSA:3.40.190.10 161 252 3.4E-17 T 09-03-2017 ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 75 291 1.5E-49 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 SUPERFAMILY SSF53850 7 26 5.74E-52 T 09-03-2017 ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 SUPERFAMILY SSF53850 65 292 5.74E-52 T 09-03-2017 ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 SMART SM00062 74 293 1.0E-49 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 Gene3D G3DSA:3.40.190.10 253 291 1.2E-30 T 09-03-2017 ARZXY2_RS04520 e1ac003ccf6a2fa4fe143c902d7a03ac 316 Gene3D G3DSA:3.40.190.10 72 160 1.2E-30 T 09-03-2017 ARZXY2_RS18385 be6cb10827152d4fab705ce267cdee93 309 Pfam PF04203 Sortase family 124 249 8.8E-22 T 09-03-2017 IPR005754 Sortase family ARZXY2_RS18385 be6cb10827152d4fab705ce267cdee93 309 Gene3D G3DSA:2.40.260.10 117 250 4.4E-44 T 09-03-2017 IPR023365 Sortase domain ARZXY2_RS18385 be6cb10827152d4fab705ce267cdee93 309 TIGRFAM TIGR01076 sortase_fam: sortase 123 249 3.3E-42 T 09-03-2017 IPR005754 Sortase family ARZXY2_RS18385 be6cb10827152d4fab705ce267cdee93 309 SUPERFAMILY SSF63817 117 250 1.23E-41 T 09-03-2017 IPR023365 Sortase domain ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 Gene3D G3DSA:3.40.1410.10 64 232 1.6E-28 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 Pfam PF07702 UTRA domain 95 225 6.8E-24 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 SMART SM00866 87 227 7.3E-14 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 2.5E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 Gene3D G3DSA:1.10.10.10 3 63 1.3E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 SMART SM00345 9 68 3.7E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 SUPERFAMILY SSF46785 3 70 1.07E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 SUPERFAMILY SSF64288 56 233 1.41E-31 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.5E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08495 c03088c658bf6525f2888d1d43e5ca97 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.5E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 SUPERFAMILY SSF69318 986 1131 3.14E-23 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 808 875 2.1E-18 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 641 705 5.5E-17 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 721 791 9.1E-19 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 SUPERFAMILY SSF63829 137 345 6.98E-6 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 SUPERFAMILY SSF63829 64 107 6.98E-6 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 940 1000 1.6E-10 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1040 1100 1.7E-7 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Gene3D G3DSA:2.60.40.1560 545 627 3.4E-4 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 SUPERFAMILY SSF69318 865 1033 5.36E-28 T 09-03-2017 ARZXY2_RS04890 c29b8b978d3dacd1f6d470a4b12e788e 1136 Gene3D G3DSA:2.130.10.130 981 1120 3.3E-14 T 09-03-2017 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 125 3.1E-15 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 PIRSF PIRSF016578 19 394 2.4E-22 T 09-03-2017 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 SUPERFAMILY SSF56645 15 252 1.44E-53 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 227 5.9E-24 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 SUPERFAMILY SSF47203 238 393 2.26E-44 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Gene3D G3DSA:2.40.110.10 129 228 7.2E-31 T 09-03-2017 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Gene3D G3DSA:1.20.140.10 229 394 1.1E-50 T 09-03-2017 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 387 7.4E-33 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16945 0ebdab1d3380d3208ff466a6b2588d4b 395 Gene3D G3DSA:1.10.540.10 15 125 1.3E-20 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 SUPERFAMILY SSF52172 8 149 6.55E-33 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 1.0E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 1.0E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 1.0E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 Gene3D G3DSA:1.10.10.10 139 234 1.5E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 Gene3D G3DSA:3.40.50.2300 8 138 4.5E-38 T 09-03-2017 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 SMART SM00448 8 130 2.3E-32 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 Pfam PF00072 Response regulator receiver domain 10 131 1.6E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 SMART SM00421 170 227 5.8E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 SUPERFAMILY SSF46894 156 234 7.48E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS05670 2cd6e91b8e059d0601b2bcba67b34abe 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 227 1.9E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS06775 d105173fcfe6d47d525c6882c8cff841 123 Pfam PF00216 Bacterial DNA-binding protein 10 69 5.8E-7 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS06775 d105173fcfe6d47d525c6882c8cff841 123 Gene3D G3DSA:4.10.520.10 9 94 5.3E-10 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ARZXY2_RS06775 d105173fcfe6d47d525c6882c8cff841 123 SUPERFAMILY SSF47729 9 93 2.8E-9 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ARZXY2_RS17535 89f7bb4d1c2b83853a18bf892ac2b8fd 340 SUPERFAMILY SSF51004 37 318 3.14E-26 T 09-03-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain ARZXY2_RS17535 89f7bb4d1c2b83853a18bf892ac2b8fd 340 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2 336 3.1E-62 T 09-03-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 ARZXY2_RS17535 89f7bb4d1c2b83853a18bf892ac2b8fd 340 Gene3D G3DSA:2.130.10.10 2 338 1.6E-59 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 Pfam PF10646 Sporulation and spore germination 166 273 7.0E-10 T 09-03-2017 IPR019606 GerMN domain ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 SUPERFAMILY SSF82171 316 465 2.86E-6 T 09-03-2017 ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 Gene3D G3DSA:2.120.10.30 312 389 2.5E-6 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 Gene3D G3DSA:2.120.10.30 173 174 2.5E-6 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 Gene3D G3DSA:2.120.10.30 77 94 2.5E-6 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 304 558 5.9E-53 T 09-03-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal ARZXY2_RS04760 da6ccfcb7455a71fbf7518bb7500302f 559 SMART SM00909 190 281 1.4E-12 T 09-03-2017 IPR019606 GerMN domain ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 Gene3D G3DSA:2.160.20.10 59 323 1.5E-35 T 09-03-2017 IPR012334 Pectin lyase fold ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SUPERFAMILY SSF51126 62 363 1.08E-39 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SMART SM00710 282 303 5.7 T 09-03-2017 IPR006626 Parallel beta-helix repeat ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SMART SM00710 171 193 2700.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SMART SM00710 194 222 4700.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SMART SM00710 254 277 3800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 SMART SM00710 223 249 850.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat ARZXY2_RS09325 599fabbfbfc1bfd4dcfb8a14a136ff6e 367 Pfam PF12708 Pectate lyase superfamily protein 61 306 5.6E-14 T 09-03-2017 IPR024535 Pectate lyase superfamily protein ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 09-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 PIRSF PIRSF000429 1 408 8.4E-129 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Pfam PF02803 Thiolase, C-terminal domain 281 406 7.7E-41 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Gene3D G3DSA:3.40.47.10 161 204 8.9E-52 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Gene3D G3DSA:3.40.47.10 287 406 8.9E-52 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 ProSitePatterns PS00099 Thiolases active site. 389 402 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Pfam PF00108 Thiolase, N-terminal domain 6 272 1.6E-74 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 406 6.5E-136 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 SUPERFAMILY SSF53901 281 406 4.55E-37 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 SUPERFAMILY SSF53901 4 280 2.18E-83 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Gene3D G3DSA:3.40.47.10 205 286 6.8E-74 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 Gene3D G3DSA:3.40.47.10 4 124 6.8E-74 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02275 ce220fe949a74ad3442e528609f1e512 408 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 150 1.2E-26 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 SUPERFAMILY SSF51735 156 329 1.79E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 SMART SM00829 14 364 2.3E-4 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 Gene3D G3DSA:3.40.50.720 187 308 2.3E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 SUPERFAMILY SSF50129 318 364 2.35E-6 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 SUPERFAMILY SSF50129 5 190 2.28E-51 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 Gene3D G3DSA:3.90.180.10 3 186 2.4E-55 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07140 5c91074ef3af87889968fcc0da16add1 368 Pfam PF00107 Zinc-binding dehydrogenase 194 316 1.4E-21 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 SUPERFAMILY SSF55347 151 318 7.85E-37 T 09-03-2017 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 Gene3D G3DSA:3.30.360.10 338 380 5.6E-50 T 09-03-2017 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 Gene3D G3DSA:3.30.360.10 166 290 5.6E-50 T 09-03-2017 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 18 137 1.1E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 Gene3D G3DSA:3.40.50.720 13 165 4.4E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 157 280 1.5E-13 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01295 eaebd7af7a5b0895079b7b89d4dde711 381 SUPERFAMILY SSF51735 11 177 4.67E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.9E-35 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.9E-35 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.9E-35 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 5.4E-35 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 3.0E-16 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.006 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 Gene3D G3DSA:2.40.50.100 20 81 1.3E-28 T 09-03-2017 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 SUPERFAMILY SSF110324 2 81 6.28E-31 T 09-03-2017 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 09-03-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS07675 9a905d234ce3bbe49553a8b753b8efee 87 Pfam PF01016 Ribosomal L27 protein 2 80 1.0E-35 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS04685 15809e4c349c5c03d8584116cc64abec 275 Gene3D G3DSA:3.40.50.1460 2 266 4.2E-54 T 09-03-2017 IPR029030 Caspase-like domain ARZXY2_RS04685 15809e4c349c5c03d8584116cc64abec 275 Pfam PF00656 Caspase domain 3 270 1.1E-32 T 09-03-2017 ARZXY2_RS04685 15809e4c349c5c03d8584116cc64abec 275 SUPERFAMILY SSF52129 192 247 2.12E-7 T 09-03-2017 IPR029030 Caspase-like domain ARZXY2_RS04685 15809e4c349c5c03d8584116cc64abec 275 SUPERFAMILY SSF52129 6 157 2.12E-7 T 09-03-2017 IPR029030 Caspase-like domain ARZXY2_RS15240 6e40ae85b6d588555e8c30484606e286 170 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 168 47.361 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 ARZXY2_RS15240 6e40ae85b6d588555e8c30484606e286 170 SUPERFAMILY SSF53927 6 167 1.67E-52 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS15240 6e40ae85b6d588555e8c30484606e286 170 Gene3D G3DSA:3.40.140.10 5 165 3.2E-60 T 09-03-2017 ARZXY2_RS15240 6e40ae85b6d588555e8c30484606e286 170 Pfam PF14437 MafB19-like deaminase 10 167 3.0E-31 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 ARZXY2_RS15240 6e40ae85b6d588555e8c30484606e286 170 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 109 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ARZXY2_RS17095 d6b0d65b721ebc3f057fee95614cbffa 350 SUPERFAMILY SSF53850 55 334 1.7E-46 T 09-03-2017 ARZXY2_RS17095 d6b0d65b721ebc3f057fee95614cbffa 350 Gene3D G3DSA:3.40.190.10 154 286 5.8E-25 T 09-03-2017 ARZXY2_RS17095 d6b0d65b721ebc3f057fee95614cbffa 350 Gene3D G3DSA:3.40.190.10 287 341 6.2E-33 T 09-03-2017 ARZXY2_RS17095 d6b0d65b721ebc3f057fee95614cbffa 350 Gene3D G3DSA:3.40.190.10 4 147 6.2E-33 T 09-03-2017 ARZXY2_RS17095 d6b0d65b721ebc3f057fee95614cbffa 350 Pfam PF13343 Bacterial extracellular solute-binding protein 103 321 3.9E-24 T 09-03-2017 ARZXY2_RS15695 70a217eaf063f28433f935cbee830477 711 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 21 201 8.1E-33 T 09-03-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal ARZXY2_RS15695 70a217eaf063f28433f935cbee830477 711 Pfam PF06202 Amylo-alpha-1,6-glucosidase 267 631 5.2E-11 T 09-03-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS15695 70a217eaf063f28433f935cbee830477 711 SUPERFAMILY SSF48208 271 649 9.64E-81 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 SUPERFAMILY SSF88946 25 111 3.14E-23 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 Pfam PF04542 Sigma-70 region 2 43 107 5.6E-17 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 SUPERFAMILY SSF88659 137 197 1.16E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 197 8.7E-24 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 Gene3D G3DSA:1.10.1740.10 27 127 1.6E-23 T 09-03-2017 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 Pfam PF08281 Sigma-70, region 4 141 193 5.4E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04635 358dd4f5323b8957d39952a9714b16c0 200 Gene3D G3DSA:1.10.10.10 138 198 4.1E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16210 c27f9ee4780a18a8e5e0652291e4da1c 441 Gene3D G3DSA:1.20.1250.20 18 203 6.3E-12 T 09-03-2017 ARZXY2_RS16210 c27f9ee4780a18a8e5e0652291e4da1c 441 Gene3D G3DSA:1.20.1250.20 224 422 5.9E-12 T 09-03-2017 ARZXY2_RS16210 c27f9ee4780a18a8e5e0652291e4da1c 441 Pfam PF13347 MFS/sugar transport protein 11 427 2.3E-92 T 09-03-2017 ARZXY2_RS16210 c27f9ee4780a18a8e5e0652291e4da1c 441 SUPERFAMILY SSF103473 8 421 3.14E-34 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16210 c27f9ee4780a18a8e5e0652291e4da1c 441 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 10 440 1.5E-125 T 09-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 SUPERFAMILY SSF46785 2 111 2.33E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 SUPERFAMILY SSF53850 90 296 1.45E-25 T 09-03-2017 ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.8E-11 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 Gene3D G3DSA:3.40.190.10 198 267 2.8E-16 T 09-03-2017 ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 Gene3D G3DSA:1.10.10.10 2 85 8.4E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 Pfam PF03466 LysR substrate binding domain 90 294 1.0E-28 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS15780 3de55765cd7227c324e25864947b7910 299 Gene3D G3DSA:3.40.190.10 90 197 5.2E-16 T 09-03-2017 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 470 560 1.7E-27 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 462 2.6E-8 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF04997 RNA polymerase Rpb1, domain 1 9 417 2.9E-80 T 09-03-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF05000 RNA polymerase Rpb1, domain 4 758 817 2.7E-10 T 09-03-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1246 0.0 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 SMART SM00663 310 589 1.8E-173 T 09-03-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF04998 RNA polymerase Rpb1, domain 5 829 1195 3.3E-60 T 09-03-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 SUPERFAMILY SSF64484 9 1249 0.0 T 09-03-2017 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Gene3D G3DSA:2.40.40.20 492 564 1.2E-37 T 09-03-2017 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Gene3D G3DSA:2.40.40.20 424 451 1.2E-37 T 09-03-2017 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Gene3D G3DSA:2.40.50.100 1037 1090 1.8E-6 T 09-03-2017 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1256 10.016 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS03455 c5fb3f867a1989d0145319bc3c9adcd4 1299 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 722 2.7E-21 T 09-03-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS18830 9dc95c94972e9066ac13233010d5c1cd 207 Gene3D G3DSA:3.40.50.360 3 180 2.5E-31 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS18830 9dc95c94972e9066ac13233010d5c1cd 207 Pfam PF03358 NADPH-dependent FMN reductase 5 155 2.0E-29 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ARZXY2_RS18830 9dc95c94972e9066ac13233010d5c1cd 207 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 200 1.2E-79 T 09-03-2017 IPR023932 Uncharacterised protein family, CE1759 ARZXY2_RS18830 9dc95c94972e9066ac13233010d5c1cd 207 SUPERFAMILY SSF52218 4 179 1.51E-26 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS04070 6d644138e1ddde6cd85a1fe944312cc8 315 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 26 269 4.9E-21 T 09-03-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 ARZXY2_RS04070 6d644138e1ddde6cd85a1fe944312cc8 315 Gene3D G3DSA:3.30.420.40 198 286 6.7E-4 T 09-03-2017 ARZXY2_RS04070 6d644138e1ddde6cd85a1fe944312cc8 315 Gene3D G3DSA:3.30.420.40 143 161 6.7E-4 T 09-03-2017 ARZXY2_RS04070 6d644138e1ddde6cd85a1fe944312cc8 315 SUPERFAMILY SSF53067 129 313 1.9E-42 T 09-03-2017 ARZXY2_RS04070 6d644138e1ddde6cd85a1fe944312cc8 315 SUPERFAMILY SSF53067 25 125 1.49E-5 T 09-03-2017 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 61 349 1.5E-89 T 09-03-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 23 349 43.612 T 09-03-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 Gene3D G3DSA:3.30.930.10 24 350 1.2E-117 T 09-03-2017 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 SUPERFAMILY SSF55681 107 350 3.38E-77 T 09-03-2017 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 Pfam PF01409 tRNA synthetases class II core domain (F) 107 349 1.7E-100 T 09-03-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 SUPERFAMILY SSF46589 27 111 9.42E-13 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 ARZXY2_RS11250 fdfd76e528f8e9203962fa82499039b3 353 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 34 101 4.4E-14 T 09-03-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ARZXY2_RS11440 121d45ff74eb664a660ac161b8fd434c 162 Gene3D G3DSA:1.25.40.10 110 157 7.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS11440 121d45ff74eb664a660ac161b8fd434c 162 SUPERFAMILY SSF48452 112 156 7.01E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 40 115 1.6E-8 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 Gene3D G3DSA:3.30.1330.30 12 116 3.6E-25 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 SMART SM00967 39 120 6.2E-15 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 SUPERFAMILY SSF55315 13 117 1.18E-14 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 Pfam PF00588 SpoU rRNA Methylase family 132 289 2.2E-33 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 SUPERFAMILY SSF75217 108 298 5.3E-38 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS11285 4aad4ad00caa21d1de13a4cc95aedf9b 303 Gene3D G3DSA:3.40.1280.10 128 296 1.3E-44 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS12500 491ca5dfc3d4b46cd8180c9db424dacd 162 SUPERFAMILY SSF117782 1 103 7.98E-34 T 09-03-2017 IPR002765 Uncharacterised protein family UPF0145 ARZXY2_RS12500 491ca5dfc3d4b46cd8180c9db424dacd 162 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 21.931 T 09-03-2017 IPR002765 Uncharacterised protein family UPF0145 ARZXY2_RS12500 491ca5dfc3d4b46cd8180c9db424dacd 162 Gene3D G3DSA:3.30.110.70 1 102 1.0E-33 T 09-03-2017 IPR002765 Uncharacterised protein family UPF0145 ARZXY2_RS12500 491ca5dfc3d4b46cd8180c9db424dacd 162 Pfam PF01906 Putative heavy-metal-binding 1 103 3.0E-35 T 09-03-2017 IPR002765 Uncharacterised protein family UPF0145 ARZXY2_RS16660 cde10141fc754e9834672b02468b4be2 279 Gene3D G3DSA:1.10.3720.10 47 275 3.0E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16660 cde10141fc754e9834672b02468b4be2 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 274 2.9E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16660 cde10141fc754e9834672b02468b4be2 279 SUPERFAMILY SSF161098 41 266 1.7E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02570 2d21a234cb3f526689299b618aed7e45 628 SUPERFAMILY SSF53474 145 300 8.87E-10 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02570 2d21a234cb3f526689299b618aed7e45 628 Gene3D G3DSA:3.40.50.1820 150 272 1.0E-7 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 SUPERFAMILY SSF46785 8 89 5.95E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 Gene3D G3DSA:1.10.10.10 9 78 9.9E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 Pfam PF07729 FCD domain 96 215 2.6E-24 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 Gene3D G3DSA:1.20.120.530 94 218 3.9E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 2.9E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 SUPERFAMILY SSF48008 94 220 4.97E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 SMART SM00895 95 219 3.3E-25 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS02930 4a3f145b9541c1705d743077606298e6 227 SMART SM00345 15 74 3.5E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS03250 bb3acc8cf9fd75981709dca3ea66b511 145 PRINTS PR01483 Fatty acid synthase signature 45 66 6.7E-8 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 ARZXY2_RS03250 bb3acc8cf9fd75981709dca3ea66b511 145 PRINTS PR01483 Fatty acid synthase signature 23 45 6.7E-8 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 ARZXY2_RS03250 bb3acc8cf9fd75981709dca3ea66b511 145 Gene3D G3DSA:3.10.129.10 6 144 2.6E-39 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS03250 bb3acc8cf9fd75981709dca3ea66b511 145 Pfam PF01575 MaoC like domain 10 98 7.9E-26 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS03250 bb3acc8cf9fd75981709dca3ea66b511 145 SUPERFAMILY SSF54637 3 135 1.73E-27 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 Pfam PF13409 Glutathione S-transferase, N-terminal domain 60 151 5.3E-10 T 09-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 Gene3D G3DSA:1.20.1050.10 176 286 3.8E-26 T 09-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 SUPERFAMILY SSF52833 39 109 8.2E-6 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 SUPERFAMILY SSF47616 173 338 3.62E-36 T 09-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 PIRSF PIRSF015753 3 320 4.1E-110 T 09-03-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 Pfam PF13410 Glutathione S-transferase, C-terminal domain 201 271 1.6E-12 T 09-03-2017 ARZXY2_RS18290 bc7041471d635f02c21e4190759f375e 351 Gene3D G3DSA:3.40.30.10 38 175 5.7E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 SUPERFAMILY SSF46689 4 85 1.63E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 Gene3D G3DSA:3.30.420.10 135 313 2.2E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 Gene3D G3DSA:1.10.10.60 13 61 7.7E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS02415 daab09481403fed3cf95d5786d762fc3 325 Pfam PF00665 Integrase core domain 139 276 4.5E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 SUPERFAMILY SSF46689 4 85 1.63E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 Gene3D G3DSA:3.30.420.10 135 313 2.2E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 Gene3D G3DSA:1.10.10.60 13 61 7.7E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS10160 daab09481403fed3cf95d5786d762fc3 325 Pfam PF00665 Integrase core domain 139 276 4.5E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS07885 6ffbc23d3816be749a7d79581d74c049 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 9 84 5.1E-29 T 09-03-2017 IPR011915 Glutaredoxin-like protein, actinobacteria ARZXY2_RS07885 6ffbc23d3816be749a7d79581d74c049 85 Pfam PF00462 Glutaredoxin 10 65 3.4E-13 T 09-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 ARZXY2_RS07885 6ffbc23d3816be749a7d79581d74c049 85 Gene3D G3DSA:3.40.30.10 9 83 1.2E-17 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07885 6ffbc23d3816be749a7d79581d74c049 85 SUPERFAMILY SSF52833 9 74 2.29E-14 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07885 6ffbc23d3816be749a7d79581d74c049 85 ProSitePatterns PS00194 Thioredoxin family active site. 10 28 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 SUPERFAMILY SSF52540 292 505 8.04E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 Pfam PF00005 ABC transporter 35 190 6.3E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 Pfam PF00005 ABC transporter 297 453 1.4E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 SMART SM00382 306 501 4.6E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 SMART SM00382 44 238 7.5E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 Gene3D G3DSA:3.40.50.300 292 506 9.8E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 SUPERFAMILY SSF52540 18 247 1.49E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS19215 c1351d5b280904531301581c6f51eebd 536 Gene3D G3DSA:3.40.50.300 17 251 1.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02840 f7e871bc832e9d0124bacb972c05bb30 231 SUPERFAMILY SSF53800 6 227 2.49E-23 T 09-03-2017 ARZXY2_RS02840 f7e871bc832e9d0124bacb972c05bb30 231 Gene3D G3DSA:3.40.50.1400 6 114 2.5E-20 T 09-03-2017 ARZXY2_RS02840 f7e871bc832e9d0124bacb972c05bb30 231 Gene3D G3DSA:3.40.50.1400 118 230 1.8E-15 T 09-03-2017 ARZXY2_RS02840 f7e871bc832e9d0124bacb972c05bb30 231 Pfam PF01903 CbiX 127 197 1.0E-5 T 09-03-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 ARZXY2_RS02840 f7e871bc832e9d0124bacb972c05bb30 231 Pfam PF01903 CbiX 11 107 2.7E-15 T 09-03-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 ARZXY2_RS10975 62aca0b47f36018efa9dec33db5836a8 197 Gene3D G3DSA:1.10.1660.10 47 118 3.5E-14 T 09-03-2017 ARZXY2_RS10975 62aca0b47f36018efa9dec33db5836a8 197 SMART SM00422 42 114 3.8E-20 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS10975 62aca0b47f36018efa9dec33db5836a8 197 Pfam PF13411 MerR HTH family regulatory protein 46 112 1.3E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS10975 62aca0b47f36018efa9dec33db5836a8 197 SUPERFAMILY SSF46955 45 130 2.15E-15 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 SUPERFAMILY SSF51735 4 249 2.7E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 Gene3D G3DSA:3.40.50.720 4 249 1.5E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00855 4c8b316ec16574207c7b189c0df356f2 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 248 4.0E-64 T 09-03-2017 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 Gene3D G3DSA:3.90.400.10 121 198 3.6E-28 T 09-03-2017 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 Pfam PF00128 Alpha amylase, catalytic domain 44 359 1.5E-69 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 SMART SM00642 29 461 8.4E-117 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 SUPERFAMILY SSF51445 402 517 2.36E-120 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 SUPERFAMILY SSF51445 18 363 2.36E-120 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 Gene3D G3DSA:3.20.20.80 19 120 2.8E-104 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 Gene3D G3DSA:3.20.20.80 398 516 2.8E-104 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03205 ba7b7ba5c06e48ebb00d4f2006a461fe 584 Gene3D G3DSA:3.20.20.80 199 358 2.8E-104 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 SUPERFAMILY SSF51905 410 448 1.1E-64 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 SUPERFAMILY SSF51905 5 308 1.1E-64 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 PRINTS PR00757 Flavin-containing amine oxidase signature 397 419 3.4E-14 T 09-03-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 PRINTS PR00757 Flavin-containing amine oxidase signature 376 395 3.4E-14 T 09-03-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 PRINTS PR00757 Flavin-containing amine oxidase signature 428 445 3.4E-14 T 09-03-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 PRINTS PR00757 Flavin-containing amine oxidase signature 7 26 3.4E-14 T 09-03-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 PRINTS PR00757 Flavin-containing amine oxidase signature 293 312 3.4E-14 T 09-03-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 Pfam PF01593 Flavin containing amine oxidoreductase 16 446 1.8E-71 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 Gene3D G3DSA:3.50.50.60 191 213 8.7E-14 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 Gene3D G3DSA:3.50.50.60 7 58 8.7E-14 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 Gene3D G3DSA:1.10.405.10 112 190 9.7E-25 T 09-03-2017 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 Gene3D G3DSA:3.90.660.10 227 395 8.5E-61 T 09-03-2017 ARZXY2_RS18365 e5a43affdcf3f721280e5085cb871700 457 SUPERFAMILY SSF54373 290 395 3.14E-30 T 09-03-2017 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 SUPERFAMILY SSF53223 21 170 2.52E-49 T 09-03-2017 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 Gene3D G3DSA:3.40.50.720 170 394 4.7E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 Gene3D G3DSA:3.40.50.10380 23 169 5.4E-48 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 SMART SM00919 172 396 6.1E-107 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 Pfam PF03949 Malic enzyme, NAD binding domain 174 396 1.7E-20 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 SMART SM01274 27 160 3.2E-71 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 PIRSF PIRSF000106 16 397 1.2E-66 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 SUPERFAMILY SSF51735 172 395 4.76E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20310 19e730631cccdb87865805debcb4f3de 397 Pfam PF00390 Malic enzyme, N-terminal domain 29 159 1.8E-23 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 116 3.2E-20 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 SUPERFAMILY SSF52788 5 125 4.45E-31 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 SUPERFAMILY SSF52788 162 189 4.45E-31 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 9 26 8.5E-7 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 84 99 8.5E-7 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 Gene3D G3DSA:3.40.50.270 7 119 9.2E-36 T 09-03-2017 ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 Gene3D G3DSA:3.40.50.270 158 190 9.2E-36 T 09-03-2017 ARZXY2_RS02380 9b6629460d9f45e1ee1c61488fb2b068 202 SMART SM00226 7 191 7.7E-11 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 SUPERFAMILY SSF55031 192 305 4.32E-30 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 PIRSF PIRSF005962 1 401 2.7E-106 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 384 2.5E-90 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 Gene3D G3DSA:3.30.70.360 191 306 3.2E-38 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 SUPERFAMILY SSF53187 2 206 3.46E-70 T 09-03-2017 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 SUPERFAMILY SSF53187 307 398 3.46E-70 T 09-03-2017 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 Pfam PF07687 Peptidase dimerisation domain 194 290 3.9E-12 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 Pfam PF01546 Peptidase family M20/M25/M40 77 395 3.5E-28 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 Gene3D G3DSA:3.40.630.10 307 399 8.0E-84 T 09-03-2017 ARZXY2_RS00985 df46dbdb29b0686024c92875a122d3a9 405 Gene3D G3DSA:3.40.630.10 2 187 8.0E-84 T 09-03-2017 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 Gene3D G3DSA:1.10.510.10 132 275 3.0E-34 T 09-03-2017 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 Pfam PF00069 Protein kinase domain 20 265 1.1E-41 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 Gene3D G3DSA:3.30.200.20 12 131 3.2E-22 T 09-03-2017 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 SMART SM00220 19 269 2.9E-38 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS19725 ea69da4dee26db36efb52e34db0592d0 276 SUPERFAMILY SSF56112 12 274 2.56E-62 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 PIRSF PIRSF001084 11 672 3.7E-257 T 09-03-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 Pfam PF02449 Beta-galactosidase 24 395 6.4E-151 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 SUPERFAMILY SSF52317 403 608 1.14E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 SUPERFAMILY SSF51445 19 377 7.15E-114 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 Pfam PF08532 Beta-galactosidase trimerisation domain 407 608 4.4E-54 T 09-03-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 Pfam PF08533 Beta-galactosidase C-terminal domain 621 669 2.9E-7 T 09-03-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 Gene3D G3DSA:3.20.20.80 21 399 2.8E-129 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS02025 d5a2f6c61fce3184df41cea5f4b0628d 672 Gene3D G3DSA:3.40.50.880 403 610 6.8E-64 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 43 263 1.8E-115 T 09-03-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 Gene3D G3DSA:3.60.20.10 47 248 7.8E-52 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 PRINTS PR00141 Proteasome component signature 181 192 2.9E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 PRINTS PR00141 Proteasome component signature 54 69 2.9E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 PRINTS PR00141 Proteasome component signature 192 203 2.9E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 Hamap MF_02113_B Proteasome subunit beta [prcB]. 1 268 46.922 T 09-03-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 SUPERFAMILY SSF56235 14 255 9.97E-55 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS08650 5255b4902ec303178db49917e8186da5 269 Pfam PF00227 Proteasome subunit 45 223 4.0E-34 T 09-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 SUPERFAMILY SSF53383 12 429 2.85E-167 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 230 246 - T 09-03-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 PIRSF PIRSF000412 2 433 6.2E-153 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 Gene3D G3DSA:3.90.1150.10 292 430 1.6E-48 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 Gene3D G3DSA:3.40.640.10 45 291 1.1E-98 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 Pfam PF00464 Serine hydroxymethyltransferase 17 397 2.8E-158 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS13285 c769f2788452e12d7b1face9cc7e9506 434 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 15 429 49.586 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 SUPERFAMILY SSF50677 228 381 1.06E-31 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Pfam PF08264 Anticodon-binding domain of tRNA 677 816 1.2E-27 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Gene3D G3DSA:3.90.740.10 232 382 1.7E-26 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Hamap MF_02005 Valine--tRNA ligase [valS]. 18 850 26.673 T 09-03-2017 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 631 3.4E-92 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 SUPERFAMILY SSF47323 646 856 5.42E-37 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Gene3D G3DSA:3.40.50.620 393 625 8.7E-99 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Gene3D G3DSA:3.40.50.620 19 225 8.7E-99 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 SUPERFAMILY SSF52374 17 229 5.2E-104 T 09-03-2017 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 SUPERFAMILY SSF52374 390 635 5.2E-104 T 09-03-2017 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 PRINTS PR00986 Valyl-tRNA synthetase signature 395 408 6.7E-19 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 PRINTS PR00986 Valyl-tRNA synthetase signature 266 283 6.7E-19 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 6.7E-19 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 PRINTS PR00986 Valyl-tRNA synthetase signature 546 564 6.7E-19 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 PRINTS PR00986 Valyl-tRNA synthetase signature 515 536 6.7E-19 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07615 4076f3467f3b562c579e2a3661b43cb6 873 Gene3D G3DSA:1.10.730.10 636 805 6.3E-36 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS13870 b9b449d75d925ea868443b21a3f85fd2 126 Gene3D G3DSA:1.20.120.160 5 122 2.1E-13 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS13870 b9b449d75d925ea868443b21a3f85fd2 126 Pfam PF01627 Hpt domain 35 112 3.7E-5 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS13870 b9b449d75d925ea868443b21a3f85fd2 126 SUPERFAMILY SSF47226 5 122 1.7E-14 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 SUPERFAMILY SSF46785 13 72 5.09E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 SUPERFAMILY SSF54909 76 151 1.09E-16 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 Gene3D G3DSA:1.10.10.10 11 64 2.6E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 Gene3D G3DSA:3.30.70.920 65 152 1.8E-22 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 Pfam PF13404 AsnC-type helix-turn-helix domain 13 53 1.7E-10 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 5.8E-9 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 5.8E-9 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 5.8E-9 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 SMART SM00344 13 119 2.5E-29 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS02660 873c694c6d25b284849cfae158c6489a 154 Pfam PF01037 Lrp/AsnC ligand binding domain 79 149 1.8E-14 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 Gene3D G3DSA:1.20.1250.20 241 426 2.5E-24 T 09-03-2017 ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 Gene3D G3DSA:1.20.1250.20 19 226 8.3E-29 T 09-03-2017 ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 SUPERFAMILY SSF103473 12 428 4.58E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 Pfam PF00083 Sugar (and other) transporter 233 428 1.7E-16 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 Pfam PF00083 Sugar (and other) transporter 26 231 8.8E-28 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS00980 2373c19604714fd7ad4f744128d9734d 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 SUPERFAMILY SSF47323 422 549 9.16E-32 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 549 9.9E-111 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 94 2.9E-20 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Gene3D G3DSA:3.30.1360.70 5 114 1.7E-27 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 SUPERFAMILY SSF52374 121 417 2.0E-74 T 09-03-2017 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 SMART SM00836 428 549 9.6E-43 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Pfam PF00750 tRNA synthetases class I (R) 122 180 3.9E-6 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Pfam PF00750 tRNA synthetases class I (R) 265 389 8.4E-6 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 549 23.398 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 SUPERFAMILY SSF55190 27 104 4.97E-18 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Gene3D G3DSA:3.40.50.620 121 433 2.2E-82 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Pfam PF05746 DALR anticodon binding domain 428 549 2.0E-31 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 Gene3D G3DSA:1.10.730.10 434 549 1.9E-39 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 3.4E-20 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 300 321 3.4E-20 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 3.4E-20 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 3.4E-20 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS05160 94d6ba8fcda259e3d36a72050a92f55d 549 SMART SM01016 4 95 9.2E-32 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 PRINTS PR01576 Peptide deformylase signature 135 146 1.5E-27 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 PRINTS PR01576 Peptide deformylase signature 166 195 1.5E-27 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 PRINTS PR01576 Peptide deformylase signature 147 165 1.5E-27 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 PRINTS PR01576 Peptide deformylase signature 66 95 1.5E-27 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 SUPERFAMILY SSF56420 32 194 6.54E-46 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 Gene3D G3DSA:3.90.45.10 36 201 1.9E-49 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 Pfam PF01327 Polypeptide deformylase 36 195 7.2E-39 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS08565 6ab351b1d1704f6a1b10cbf001d79f5c 240 Hamap MF_00163 Peptide deformylase [def]. 33 201 24.191 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07375 e345251be6608fea2d87175a52e4ee63 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS13470 e345251be6608fea2d87175a52e4ee63 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 SUPERFAMILY SSF53098 141 320 1.52E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS18205 e345251be6608fea2d87175a52e4ee63 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 SUPERFAMILY SSF47203 231 382 3.22E-23 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 PIRSF PIRSF016578 2 386 2.0E-39 T 09-03-2017 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 82 2.4E-5 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 Gene3D G3DSA:1.20.140.10 212 382 1.9E-31 T 09-03-2017 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 Gene3D G3DSA:1.10.540.10 9 90 6.1E-15 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 SUPERFAMILY SSF56645 11 218 3.4E-35 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 Gene3D G3DSA:2.40.110.10 125 211 1.4E-14 T 09-03-2017 ARZXY2_RS08800 9c2d42e3e25f7e0554cd3f3c11ddce68 386 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 241 368 4.9E-17 T 09-03-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 4.5E-55 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 09-03-2017 IPR020081 SsrA-binding protein, conserved site ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 68.956 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 Pfam PF01668 SmpB protein 9 73 1.3E-28 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 SUPERFAMILY SSF74982 4 133 2.62E-50 T 09-03-2017 IPR023620 Small protein B ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 Gene3D G3DSA:2.40.280.10 8 128 1.1E-49 T 09-03-2017 IPR023620 Small protein B ARZXY2_RS04970 94e9d0505811e624300e9236a64ed402 157 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 1.0E-54 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 Pfam PF07702 UTRA domain 106 243 5.3E-17 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 SMART SM00345 27 84 7.9E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 Gene3D G3DSA:3.40.1410.10 83 248 1.9E-28 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 SUPERFAMILY SSF46785 16 99 9.65E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 84 1.3E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 Gene3D G3DSA:1.10.10.10 16 82 6.4E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 5.6E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 5.6E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 SMART SM00866 105 244 1.6E-15 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS04590 4a2c05b9ee168224262210c520ff4954 268 SUPERFAMILY SSF64288 72 248 2.04E-31 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 SUPERFAMILY SSF88659 126 191 4.67E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 191 1.3E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 SUPERFAMILY SSF88946 18 124 3.92E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 Pfam PF13490 Putative zinc-finger 205 238 7.4E-6 T 09-03-2017 IPR027383 Putative zinc-finger ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 Pfam PF04542 Sigma-70 region 2 41 109 3.0E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 Gene3D G3DSA:1.10.10.10 133 192 9.9E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17405 7d80d3811dca9234e9c05d20c813cd36 537 Gene3D G3DSA:1.10.1740.10 19 116 1.1E-18 T 09-03-2017 ARZXY2_RS00660 eb6af16c8b091e3e70f5482e7cc2b91c 159 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 15 150 9.0E-37 T 09-03-2017 IPR011747 Conserved hypothetical protein CHP02241 ARZXY2_RS00660 eb6af16c8b091e3e70f5482e7cc2b91c 159 Pfam PF06841 T4-like virus tail tube protein gp19 19 150 1.7E-38 T 09-03-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 Gene3D G3DSA:1.10.10.10 6 84 6.5E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.4E-13 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 SUPERFAMILY SSF53850 88 301 2.17E-35 T 09-03-2017 ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 Pfam PF03466 LysR substrate binding domain 89 295 9.0E-39 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 SUPERFAMILY SSF46785 6 85 5.79E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 Gene3D G3DSA:3.40.190.10 92 180 4.2E-14 T 09-03-2017 ARZXY2_RS16385 ae53741a670e5b7b8be7306be631e73e 310 Gene3D G3DSA:3.40.190.10 181 266 6.3E-28 T 09-03-2017 ARZXY2_RS00270 8877b5b322ef032bc20206ec11cad183 404 Pfam PF06187 Protein of unknown function (DUF993) 5 402 4.8E-179 T 09-03-2017 IPR009334 Protein of unknown function DUF993 ARZXY2_RS00270 8877b5b322ef032bc20206ec11cad183 404 SUPERFAMILY SSF51569 154 350 1.34E-9 T 09-03-2017 ARZXY2_RS00270 8877b5b322ef032bc20206ec11cad183 404 Gene3D G3DSA:3.20.20.70 151 342 2.7E-6 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 5.3E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 5.6E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 5.6E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 SUPERFAMILY SSF48498 100 212 1.4E-27 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 Gene3D G3DSA:1.10.357.10 20 211 6.5E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS04445 574abb0d1c7721bb4936ae09e352e073 217 SUPERFAMILY SSF46689 22 104 9.48E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 SUPERFAMILY SSF53218 193 347 1.96E-26 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Gene3D G3DSA:2.40.340.10 354 420 2.7E-7 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 SUPERFAMILY SSF63867 353 421 6.54E-9 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Gene3D G3DSA:3.40.980.10 169 347 2.1E-41 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Pfam PF00994 Probable molybdopterin binding domain 198 342 2.0E-19 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Pfam PF03454 MoeA C-terminal region (domain IV) 360 420 4.1E-7 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Gene3D G3DSA:2.170.190.11 64 159 4.2E-9 T 09-03-2017 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 Pfam PF03453 MoeA N-terminal region (domain I and II) 36 185 5.0E-26 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 SUPERFAMILY SSF63882 24 194 2.35E-32 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 SMART SM00852 198 344 7.5E-24 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS16480 4c91cff28bc2a3bb7ad4966a1ac5c8eb 444 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 270 283 - T 09-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 SUPERFAMILY SSF53448 411 602 6.84E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 SUPERFAMILY SSF53756 121 388 1.83E-10 T 09-03-2017 ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 Pfam PF00535 Glycosyl transferase family 2 412 533 1.1E-5 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 Pfam PF13524 Glycosyl transferases group 1 295 387 4.7E-18 T 09-03-2017 ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 Gene3D G3DSA:3.90.550.10 411 598 3.2E-15 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02610 65e4a5e632ab7bb497e1e429a06f7955 627 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 150 223 5.6E-9 T 09-03-2017 IPR024542 Domain of unknown function DUF3880 ARZXY2_RS01200 749f861c5e0abe197f2edbd8e4cfa0c6 653 SUPERFAMILY SSF53448 398 505 4.03E-11 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01200 749f861c5e0abe197f2edbd8e4cfa0c6 653 Gene3D G3DSA:3.90.550.10 76 245 1.9E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01200 749f861c5e0abe197f2edbd8e4cfa0c6 653 SUPERFAMILY SSF53448 74 244 1.2E-25 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01200 749f861c5e0abe197f2edbd8e4cfa0c6 653 Pfam PF03552 Cellulose synthase 128 626 3.6E-24 T 09-03-2017 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 SUPERFAMILY SSF53738 258 365 1.73E-29 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Gene3D G3DSA:3.40.120.10 176 250 1.1E-24 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 445 43.984 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Gene3D G3DSA:3.30.310.50 370 445 2.3E-16 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 367 8.8E-33 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 SUPERFAMILY SSF53738 4 181 1.18E-43 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 440 4.2E-11 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 SUPERFAMILY SSF53738 158 256 2.12E-27 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 254 2.1E-19 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 1.7E-171 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Gene3D G3DSA:3.40.120.10 251 369 1.9E-32 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 4.1E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 4.1E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 4.1E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Gene3D G3DSA:3.40.120.10 3 154 2.0E-42 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 SUPERFAMILY SSF55957 359 446 8.63E-21 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS03740 ff0beb1d8e3bd0a9004eb2dffdd6b1b4 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 2.1E-39 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS20485 acc4181985219dc84f942b066e5cf7b3 364 Gene3D G3DSA:2.40.50.90 25 127 5.8E-28 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS20485 acc4181985219dc84f942b066e5cf7b3 364 Pfam PF00565 Staphylococcal nuclease homologue 51 157 7.9E-17 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS20485 acc4181985219dc84f942b066e5cf7b3 364 SUPERFAMILY SSF50199 25 159 7.72E-28 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS20485 acc4181985219dc84f942b066e5cf7b3 364 SMART SM00318 26 159 5.8E-22 T 09-03-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold ARZXY2_RS20485 acc4181985219dc84f942b066e5cf7b3 364 ProSitePatterns PS01284 Thermonuclease family signature 2. 100 110 - T 09-03-2017 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 09-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 Pfam PF12327 FtsZ family, C-terminal domain 219 313 1.8E-33 T 09-03-2017 IPR024757 Cell division protein FtsZ, C-terminal ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 PRINTS PR00423 Cell division protein FtsZ signature 95 115 3.4E-50 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 PRINTS PR00423 Cell division protein FtsZ signature 123 144 3.4E-50 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 PRINTS PR00423 Cell division protein FtsZ signature 186 208 3.4E-50 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 PRINTS PR00423 Cell division protein FtsZ signature 209 230 3.4E-50 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 09-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 Gene3D G3DSA:3.30.1330.20 212 315 2.2E-47 T 09-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 378 38.273 T 09-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 Gene3D G3DSA:3.40.50.1440 11 211 4.6E-90 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 SUPERFAMILY SSF55307 201 314 1.79E-42 T 09-03-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 323 1.2E-125 T 09-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 SUPERFAMILY SSF52490 9 205 5.36E-67 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 SMART SM00864 10 202 1.9E-107 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 SMART SM00865 204 321 2.6E-54 T 09-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 ARZXY2_RS10830 32c1d87b23f7807794c7763e1020d66c 406 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 2.8E-37 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 ARZXY2_RS16280 b7ca60b10a5cfed35823031454796d2d 211 Gene3D G3DSA:1.10.10.10 70 158 7.8E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16280 b7ca60b10a5cfed35823031454796d2d 211 SUPERFAMILY SSF46785 68 159 2.84E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16280 b7ca60b10a5cfed35823031454796d2d 211 Pfam PF03551 Transcriptional regulator PadR-like family 79 147 1.6E-16 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS18590 911b9044eec1a7579e731b50a2c47236 183 SUPERFAMILY SSF82708 126 181 3.14E-11 T 09-03-2017 IPR001374 R3H domain GO:0003676 ARZXY2_RS18590 911b9044eec1a7579e731b50a2c47236 183 Gene3D G3DSA:3.30.1370.50 116 182 1.2E-21 T 09-03-2017 IPR001374 R3H domain GO:0003676 ARZXY2_RS18590 911b9044eec1a7579e731b50a2c47236 183 Gene3D G3DSA:3.30.300.120 33 115 4.1E-19 T 09-03-2017 ARZXY2_RS18590 911b9044eec1a7579e731b50a2c47236 183 Pfam PF01424 R3H domain 125 181 1.0E-16 T 09-03-2017 IPR001374 R3H domain GO:0003676 ARZXY2_RS18590 911b9044eec1a7579e731b50a2c47236 183 SMART SM00393 105 183 2.4E-17 T 09-03-2017 IPR001374 R3H domain GO:0003676 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 SUPERFAMILY SSF82679 92 197 5.23E-36 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 Gene3D G3DSA:2.30.30.30 216 275 7.2E-24 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 SMART SM00738 90 198 2.3E-40 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 Gene3D G3DSA:3.30.70.940 92 198 6.2E-41 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 Pfam PF02357 Transcription termination factor nusG 92 194 6.3E-23 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 PRINTS PR00338 Transcription termination factor NUSG signature 145 157 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 PRINTS PR00338 Transcription termination factor NUSG signature 251 267 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 PRINTS PR00338 Transcription termination factor NUSG signature 233 248 1.5E-12 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 SMART SM00739 221 248 0.0081 T 09-03-2017 IPR005824 KOW ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 SUPERFAMILY SSF50104 220 275 7.22E-14 T 09-03-2017 IPR008991 Translation protein SH3-like domain ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 93 275 9.9E-56 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 ARZXY2_RS03405 585eabd1dde4c4e739038c29776abff0 275 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 90 275 22.298 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 ARZXY2_RS17335 0c38976167192821fa3872559b846611 419 Pfam PF13416 Bacterial extracellular solute-binding protein 62 344 6.8E-41 T 09-03-2017 ARZXY2_RS17335 0c38976167192821fa3872559b846611 419 SUPERFAMILY SSF53850 43 415 6.92E-71 T 09-03-2017 ARZXY2_RS17335 0c38976167192821fa3872559b846611 419 Gene3D G3DSA:3.40.190.10 169 341 2.7E-42 T 09-03-2017 ARZXY2_RS17335 0c38976167192821fa3872559b846611 419 Gene3D G3DSA:3.40.190.10 50 168 2.8E-17 T 09-03-2017 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 SUPERFAMILY SSF52540 1 427 6.16E-166 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Gene3D G3DSA:1.10.300.10 101 193 3.9E-34 T 09-03-2017 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Gene3D G3DSA:3.90.170.10 265 423 1.2E-63 T 09-03-2017 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Gene3D G3DSA:3.40.440.10 194 264 2.5E-64 T 09-03-2017 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Gene3D G3DSA:3.40.440.10 2 93 2.5E-64 T 09-03-2017 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 09-03-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 SMART SM00788 3 422 5.4E-273 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 193.359 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 1.3E-158 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 3.2E-167 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS16135 bcd21a7ec56f28e4572af76cd417880d 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 09-03-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 SUPERFAMILY SSF52540 10 175 4.97E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 Gene3D G3DSA:3.40.50.300 8 176 6.0E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 Hamap MF_00109 Shikimate kinase [aroK]. 7 173 23.432 T 09-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 ProSitePatterns PS01128 Shikimate kinase signature. 62 90 - T 09-03-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 Pfam PF01202 Shikimate kinase 16 171 6.3E-37 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 PRINTS PR01100 Shikimate kinase family signature 82 91 3.4E-15 T 09-03-2017 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 PRINTS PR01100 Shikimate kinase family signature 34 47 3.4E-15 T 09-03-2017 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 PRINTS PR01100 Shikimate kinase family signature 102 119 3.4E-15 T 09-03-2017 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 PRINTS PR01100 Shikimate kinase family signature 10 25 3.4E-15 T 09-03-2017 ARZXY2_RS08085 ed56b4c9c61655ddabc047236e912036 184 PRINTS PR01100 Shikimate kinase family signature 61 69 3.4E-15 T 09-03-2017 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 5.9E-137 T 09-03-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 153 4.5E-61 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 2.3E-68 T 09-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 Gene3D G3DSA:3.40.50.720 2 161 3.8E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PIRSF PIRSF000149 1 335 1.5E-135 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 09-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 SUPERFAMILY SSF51735 2 180 1.06E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.0E-37 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 2.0E-37 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 2.0E-37 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 2.0E-37 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 2.0E-37 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 SUPERFAMILY SSF55347 152 314 3.27E-70 T 09-03-2017 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 SMART SM00846 3 153 1.7E-94 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09075 324e3447aa294f3389fd0cd1e9f2c3a9 336 Gene3D G3DSA:3.30.360.10 162 316 3.7E-74 T 09-03-2017 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 PIRSF PIRSF002191 1 117 1.6E-47 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.986 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 Pfam PF01245 Ribosomal protein L19 3 112 3.2E-48 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 SUPERFAMILY SSF50104 1 114 6.62E-45 T 09-03-2017 IPR008991 Translation protein SH3-like domain ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 09-03-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.0E-40 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.0E-40 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.0E-40 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07025 0ffcc4571d66ed051631bcdc010f1b8b 117 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 1.6E-48 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS09135 0badf2d690ab0202a3e9c58f33449b16 457 SUPERFAMILY SSF89796 69 179 2.62E-13 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS09135 0badf2d690ab0202a3e9c58f33449b16 457 Gene3D G3DSA:3.40.50.10540 195 396 7.3E-62 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS09135 0badf2d690ab0202a3e9c58f33449b16 457 Pfam PF02515 CoA-transferase family III 199 408 1.5E-42 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 ARZXY2_RS09135 0badf2d690ab0202a3e9c58f33449b16 457 Gene3D G3DSA:3.40.50.10540 82 150 3.0E-4 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS09135 0badf2d690ab0202a3e9c58f33449b16 457 SUPERFAMILY SSF89796 197 410 3.66E-51 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS08985 8715d4a3035d1bbc99fa30155970e28d 261 SMART SM00382 32 226 2.8E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08985 8715d4a3035d1bbc99fa30155970e28d 261 Gene3D G3DSA:3.40.50.300 3 234 1.9E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08985 8715d4a3035d1bbc99fa30155970e28d 261 SUPERFAMILY SSF52540 4 234 1.09E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08985 8715d4a3035d1bbc99fa30155970e28d 261 Pfam PF00005 ABC transporter 23 174 4.8E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08985 8715d4a3035d1bbc99fa30155970e28d 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 3.9E-103 T 09-03-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 ARZXY2_RS19305 6c4a4f18011f180e72ecba473c9989f6 368 SUPERFAMILY SSF56349 26 344 3.53E-32 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS19305 6c4a4f18011f180e72ecba473c9989f6 368 Pfam PF00589 Phage integrase family 160 338 3.2E-22 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS19305 6c4a4f18011f180e72ecba473c9989f6 368 Gene3D G3DSA:1.10.443.10 146 344 4.2E-30 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS19305 6c4a4f18011f180e72ecba473c9989f6 368 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 30 105 3.0E-6 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 72 1.7E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 SMART SM00895 82 204 9.6E-18 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 Gene3D G3DSA:1.10.10.10 8 72 4.7E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 SMART SM00345 14 72 8.4E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 SUPERFAMILY SSF46785 12 76 8.17E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 Gene3D G3DSA:1.20.120.530 75 215 3.7E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 SUPERFAMILY SSF48008 80 211 7.32E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS00925 621063a9d2a7d4bbc82c0662db3c3205 221 Pfam PF07729 FCD domain 82 202 1.2E-26 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS10270 9a562f4209a16f92c4fe8a7e08ca78e8 273 Gene3D G3DSA:3.20.20.70 3 264 8.0E-90 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10270 9a562f4209a16f92c4fe8a7e08ca78e8 273 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 260 2.3E-79 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 ARZXY2_RS10270 9a562f4209a16f92c4fe8a7e08ca78e8 273 SUPERFAMILY SSF51366 13 262 3.3E-76 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS10270 9a562f4209a16f92c4fe8a7e08ca78e8 273 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 57 74 - T 09-03-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 ARZXY2_RS10270 9a562f4209a16f92c4fe8a7e08ca78e8 273 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 263 32.622 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 ARZXY2_RS13390 583531d421aa14f58268220190ea039d 332 SUPERFAMILY SSF50494 105 314 2.42E-16 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS13390 583531d421aa14f58268220190ea039d 332 Gene3D G3DSA:2.40.10.10 133 211 9.6E-10 T 09-03-2017 ARZXY2_RS11540 67b7537e1a770bf00242974055cd7887 160 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 106 1.6E-18 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 ARZXY2_RS11540 67b7537e1a770bf00242974055cd7887 160 Gene3D G3DSA:3.40.140.10 4 129 1.7E-38 T 09-03-2017 ARZXY2_RS11540 67b7537e1a770bf00242974055cd7887 160 SUPERFAMILY SSF53927 9 127 8.2E-37 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 Gene3D G3DSA:1.10.10.10 11 80 8.4E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 SUPERFAMILY SSF53067 89 389 2.26E-45 T 09-03-2017 ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 SUPERFAMILY SSF46785 11 69 2.39E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 Pfam PF09339 IclR helix-turn-helix domain 30 60 3.1E-5 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 Gene3D G3DSA:3.30.420.40 85 225 8.8E-29 T 09-03-2017 ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 Pfam PF00480 ROK family 90 362 7.8E-35 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS03185 c60ad96f7eabb94c9113db3a631c0458 405 Gene3D G3DSA:3.30.420.40 226 365 5.3E-24 T 09-03-2017 ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 SUPERFAMILY SSF51735 16 174 7.0E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 Gene3D G3DSA:3.40.50.720 15 184 1.3E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 Pfam PF02153 Prephenate dehydrogenase 30 264 1.3E-49 T 09-03-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 SUPERFAMILY SSF55021 299 359 7.63E-7 T 09-03-2017 ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 Gene3D G3DSA:3.30.70.260 301 361 7.4E-6 T 09-03-2017 ARZXY2_RS11035 f7c974f6b9befcdff1085af2ddf0eda6 368 SUPERFAMILY SSF48179 179 264 2.38E-23 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS12870 c7c667b3757c9c7e7133e18c765d10d8 405 Gene3D G3DSA:2.40.440.10 250 379 2.9E-20 T 09-03-2017 ARZXY2_RS12870 c7c667b3757c9c7e7133e18c765d10d8 405 SUPERFAMILY SSF141523 250 378 1.96E-26 T 09-03-2017 ARZXY2_RS12870 c7c667b3757c9c7e7133e18c765d10d8 405 Pfam PF13205 Bacterial Ig-like domain 154 248 8.1E-8 T 09-03-2017 IPR032812 SbsA, Ig-like domain ARZXY2_RS12870 c7c667b3757c9c7e7133e18c765d10d8 405 Pfam PF03734 L,D-transpeptidase catalytic domain 252 378 6.2E-18 T 09-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 6 20 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 171 184 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 81 92 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 106 114 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00097 Anthranilate synthase component II signature 126 138 1.5E-34 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 SUPERFAMILY SSF52317 5 193 2.72E-55 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 Gene3D G3DSA:3.40.50.880 5 193 3.9E-64 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 6 193 3.1E-61 T 09-03-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 Pfam PF00117 Glutamine amidotransferase class-I 8 191 1.4E-52 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 7.8E-10 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 7.8E-10 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.2E-14 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 4.2E-14 T 09-03-2017 ARZXY2_RS18450 da9cfbddd590274b904af3074da409de 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 4.2E-14 T 09-03-2017 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 Pfam PF13377 Periplasmic binding protein-like domain 170 323 3.0E-32 T 09-03-2017 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 7.9E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 SMART SM00354 5 75 1.3E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 SUPERFAMILY SSF47413 4 63 8.44E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 Gene3D G3DSA:3.40.50.2300 174 304 1.1E-37 T 09-03-2017 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 SUPERFAMILY SSF53822 62 310 3.93E-49 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 Gene3D G3DSA:1.10.260.40 6 57 6.6E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16885 e0dcb3a6257d03b237d7bbb12f6ab85c 332 Gene3D G3DSA:3.40.50.2300 58 173 4.8E-25 T 09-03-2017 ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 Gene3D G3DSA:3.90.180.10 2 176 1.6E-55 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 SUPERFAMILY SSF50129 2 162 3.46E-56 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 Pfam PF00107 Zinc-binding dehydrogenase 183 307 8.1E-26 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 135 3.8E-29 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 SMART SM00829 7 348 5.9E-5 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 Gene3D G3DSA:3.40.50.720 177 291 2.7E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06075 7afda392d49758e3eaef30935a16330a 350 SUPERFAMILY SSF51735 144 313 1.97E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04505 06fa0854d6887f2d9851dc2db3c6b17d 325 Gene3D G3DSA:3.20.20.300 2 322 4.0E-61 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS04505 06fa0854d6887f2d9851dc2db3c6b17d 325 SUPERFAMILY SSF51445 9 322 1.9E-53 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS04505 06fa0854d6887f2d9851dc2db3c6b17d 325 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 16 319 3.4E-41 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 SUPERFAMILY SSF47384 603 683 6.67E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Pfam PF00512 His Kinase A (phospho-acceptor) domain 619 683 8.4E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Gene3D G3DSA:1.20.120.620 376 473 1.2E-18 T 09-03-2017 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 SUPERFAMILY SSF52402 232 354 6.03E-10 T 09-03-2017 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 SUPERFAMILY SSF55874 674 839 6.68E-28 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Gene3D G3DSA:3.30.565.10 669 840 3.3E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Gene3D G3DSA:3.40.50.300 2 210 2.4E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Gene3D G3DSA:3.40.50.620 227 354 6.3E-11 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 725 840 1.3E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Pfam PF00582 Universal stress protein family 232 346 3.0E-8 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Pfam PF13493 Domain of unknown function (DUF4118) 381 485 1.7E-22 T 09-03-2017 IPR025201 Sensor protein KdpD, transmembrane domain ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 SMART SM00388 615 683 1.4E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Gene3D G3DSA:1.10.287.130 608 668 4.9E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 782 5.9E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 825 838 5.9E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 801 819 5.9E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 786 796 5.9E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 8.3E-78 T 09-03-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 ARZXY2_RS17770 f710982c96b225c30f16a8ffe2bb187a 857 SMART SM00387 723 841 4.5E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 SUPERFAMILY SSF52141 31 251 1.37E-68 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 SMART SM00987 75 240 8.2E-32 T 09-03-2017 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 83 92 - T 09-03-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 Gene3D G3DSA:3.40.470.10 27 252 8.8E-77 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 Pfam PF03167 Uracil DNA glycosylase superfamily 78 239 2.6E-16 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 33 251 32.808 T 09-03-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14340 eba5af276e98783e0f3eeb56c4b7a8be 255 SMART SM00986 75 240 8.2E-32 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 SUPERFAMILY SSF51905 2 177 8.82E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 SUPERFAMILY SSF51905 277 384 8.82E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 Gene3D G3DSA:3.30.9.10 168 331 1.3E-46 T 09-03-2017 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 Gene3D G3DSA:3.50.50.60 1 167 4.5E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 Pfam PF01494 FAD binding domain 1 318 4.7E-19 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.5E-12 T 09-03-2017 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.5E-12 T 09-03-2017 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.5E-12 T 09-03-2017 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 1.5E-12 T 09-03-2017 ARZXY2_RS02815 aeb536e3d00b3a18d98ffd2739340ae6 447 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 323 4.6E-72 T 09-03-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 SUPERFAMILY SSF47384 116 194 6.47E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 SMART SM00388 130 196 2.1E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 SUPERFAMILY SSF55874 186 351 2.23E-47 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 SMART SM00387 241 353 6.0E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 Gene3D G3DSA:3.30.565.10 182 354 4.6E-50 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 292 1.3E-21 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 1.3E-21 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 350 1.3E-21 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 306 1.3E-21 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 195 5.6E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 351 3.8E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14915 74de95e746d14c50f9c6c1e6275ef15d 407 Gene3D G3DSA:1.10.287.130 122 181 1.7E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS09465 79a07042fe2f436feb89ce379126e0a7 249 Gene3D G3DSA:3.40.50.1820 3 243 6.4E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09465 79a07042fe2f436feb89ce379126e0a7 249 SUPERFAMILY SSF53474 3 247 4.09E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09465 79a07042fe2f436feb89ce379126e0a7 249 Pfam PF01738 Dienelactone hydrolase family 13 243 2.2E-34 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 ARZXY2_RS18735 d45621dac1fdd66a38d1b4a5d801486b 426 SUPERFAMILY SSF55874 304 416 5.02E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18735 d45621dac1fdd66a38d1b4a5d801486b 426 Gene3D G3DSA:3.30.565.10 330 419 2.5E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18735 d45621dac1fdd66a38d1b4a5d801486b 426 Pfam PF07730 Histidine kinase 216 281 2.2E-18 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS05690 8f03d06860ad667d32afef6dd7894843 272 Pfam PF00753 Metallo-beta-lactamase superfamily 41 202 1.2E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05690 8f03d06860ad667d32afef6dd7894843 272 Gene3D G3DSA:3.60.15.10 16 231 4.9E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05690 8f03d06860ad667d32afef6dd7894843 272 SMART SM00849 43 202 5.7E-25 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05690 8f03d06860ad667d32afef6dd7894843 272 SUPERFAMILY SSF56281 33 271 8.78E-52 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 272 364 1.1E-10 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 SUPERFAMILY SSF81296 251 364 1.05E-26 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 Pfam PF00174 Oxidoreductase molybdopterin binding domain 56 227 1.9E-52 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 207 220 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 191 204 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 345 358 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 96 107 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 44 60 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 332 344 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 PRINTS PR00407 Eukaryotic molybdopterin domain signature 174 190 1.9E-18 T 09-03-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 Gene3D G3DSA:2.60.40.650 267 364 1.9E-23 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 Gene3D G3DSA:3.90.420.10 32 239 2.0E-68 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS20515 b37ed5a2d3b64bc385aa2827fb72ad92 365 SUPERFAMILY SSF56524 35 285 4.19E-69 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 371 9.5E-17 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 Gene3D G3DSA:3.40.50.300 2 167 4.1E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 Gene3D G3DSA:3.40.50.300 264 370 4.1E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 SUPERFAMILY SSF52540 268 369 1.26E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 SUPERFAMILY SSF52540 2 220 1.26E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 09-03-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 ProSitePatterns PS00618 RecF protein signature 2. 339 357 - T 09-03-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 386 4.7E-111 T 09-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 397 88.732 T 09-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS18555 5d714e05cc7a60f80e72cf0a3be313ac 397 SMART SM00382 22 392 1.5E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS16710 d1090d9bc5bd1794500276e110b939b5 307 SUPERFAMILY SSF53613 11 300 8.57E-58 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS16710 d1090d9bc5bd1794500276e110b939b5 307 Pfam PF00294 pfkB family carbohydrate kinase 13 296 2.2E-34 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS16710 d1090d9bc5bd1794500276e110b939b5 307 Gene3D G3DSA:3.40.1190.20 5 303 2.2E-58 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS16710 d1090d9bc5bd1794500276e110b939b5 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS16305 bbb4b1845766771202583ca608d352b0 479 Pfam PF02720 Domain of unknown function (DUF222) 8 395 2.3E-26 T 09-03-2017 IPR003870 Domain of unknown function DUF222 ARZXY2_RS16305 bbb4b1845766771202583ca608d352b0 479 SMART SM00507 386 438 2.3E-6 T 09-03-2017 IPR003615 HNH nuclease ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 135 145 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 Pfam PF00920 Dehydratase family 47 570 1.9E-214 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 17 573 46.148 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 31 570 5.9E-222 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 SUPERFAMILY SSF52016 395 572 3.92E-57 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 SUPERFAMILY SSF143975 7 394 1.1E-138 T 09-03-2017 ARZXY2_RS05620 981b22ea66f5e7b1761769622b142ee3 573 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 481 492 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 SUPERFAMILY SSF54768 112 227 5.66E-21 T 09-03-2017 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 Gene3D G3DSA:3.30.160.20 155 224 8.1E-22 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 Pfam PF00035 Double-stranded RNA binding motif 158 223 1.5E-12 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 SMART SM00535 18 151 8.8E-53 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 9 222 1.8E-66 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 SMART SM00358 158 224 7.9E-18 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 SUPERFAMILY SSF69065 3 159 1.5E-44 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 ProSitePatterns PS00517 Ribonuclease III family signature. 40 48 - T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 Gene3D G3DSA:1.10.1520.10 5 147 1.1E-42 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 Pfam PF14622 Ribonuclease-III-like 16 140 9.6E-34 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 ARZXY2_RS05835 2aa54b1aba5f61ed22e958db0de65b6b 236 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 220 27.837 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 ARZXY2_RS15485 0d69ab225734ac0c4eb618539220f37d 393 Pfam PF13556 PucR C-terminal helix-turn-helix domain 337 391 2.8E-16 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS17915 478e2ce1a4fc3153b04fb48d50bfe7be 107 SUPERFAMILY SSF69118 9 105 2.04E-29 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS17915 478e2ce1a4fc3153b04fb48d50bfe7be 107 Gene3D G3DSA:1.20.1290.10 11 105 1.6E-25 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS17915 478e2ce1a4fc3153b04fb48d50bfe7be 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 102 1.0E-22 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Pfam PF08448 PAS fold 174 279 2.4E-10 T 09-03-2017 IPR013656 PAS fold-4 ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 486 4.9E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 SUPERFAMILY SSF55785 176 284 7.5E-8 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 SMART SM00387 387 488 8.1E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Gene3D G3DSA:3.30.450.20 174 276 1.3E-6 T 09-03-2017 ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Gene3D G3DSA:3.30.565.10 353 487 9.2E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Pfam PF07568 Histidine kinase 293 356 1.2E-20 T 09-03-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 SUPERFAMILY SSF55874 364 486 1.7E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04820 6c611d1f3cc7ef586e30a06a37748788 489 Pfam PF12282 Signal transduction histidine kinase 5 146 7.3E-48 T 09-03-2017 IPR022066 Signal transduction histidine kinase ARZXY2_RS09230 472a88ede6ac51ef6554f1816262d01b 412 PIRSF PIRSF038800 4 412 9.1E-147 T 09-03-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 ARZXY2_RS09230 472a88ede6ac51ef6554f1816262d01b 412 Pfam PF00266 Aminotransferase class-V 118 332 3.0E-22 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS09230 472a88ede6ac51ef6554f1816262d01b 412 Gene3D G3DSA:3.40.640.10 120 252 3.1E-18 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS09230 472a88ede6ac51ef6554f1816262d01b 412 Gene3D G3DSA:3.90.1150.10 265 410 1.9E-42 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS09230 472a88ede6ac51ef6554f1816262d01b 412 SUPERFAMILY SSF53383 9 408 2.27E-72 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 Gene3D G3DSA:2.40.30.10 381 460 5.4E-5 T 09-03-2017 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 PRINTS PR00315 GTP-binding elongation factor signature 109 119 1.9E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 PRINTS PR00315 GTP-binding elongation factor signature 125 136 1.9E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 PRINTS PR00315 GTP-binding elongation factor signature 89 97 1.9E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 PRINTS PR00315 GTP-binding elongation factor signature 26 39 1.9E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 PRINTS PR00315 GTP-binding elongation factor signature 162 171 1.9E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 26 459 1.3E-147 T 09-03-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 SUPERFAMILY SSF52540 23 239 3.94E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 Gene3D G3DSA:2.40.30.10 249 380 2.4E-23 T 09-03-2017 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 82 97 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 SUPERFAMILY SSF50447 250 353 1.66E-13 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 SUPERFAMILY SSF50465 359 460 8.15E-25 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 Pfam PF00009 Elongation factor Tu GTP binding domain 26 234 4.0E-41 T 09-03-2017 ARZXY2_RS02860 9e89e9004b1e53628f4715b8e161d09d 473 Gene3D G3DSA:3.40.50.300 23 239 8.4E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 SUPERFAMILY SSF52266 405 585 3.82E-17 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Gene3D G3DSA:3.40.50.1110 390 585 8.2E-12 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 263 314 3.8E-14 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 155 207 1.1E-18 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 209 261 5.0E-15 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 102 153 8.8E-10 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 316 359 6.6E-8 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF08310 LGFP repeat 51 99 1.1E-9 T 09-03-2017 IPR013207 LGFP ARZXY2_RS03060 0e59ecd9b7f08f973373b992a8b69497 590 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 410 574 2.8E-10 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 50.257 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 129 2.0E-65 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 68 1.3E-17 T 09-03-2017 IPR020603 MraZ domain ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 136 2.5E-15 T 09-03-2017 IPR020603 MraZ domain ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 134 3.9E-34 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 ARZXY2_RS10890 28f2a5c7a729da8918c0991310bf290c 143 SUPERFAMILY SSF89447 2 135 1.83E-43 T 09-03-2017 ARZXY2_RS05800 f31d02e4477a01a504dcef8b65e58bf0 196 SUPERFAMILY SSF53335 10 192 6.7E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05800 f31d02e4477a01a504dcef8b65e58bf0 196 PIRSF PIRSF004553 9 196 1.0E-44 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS05800 f31d02e4477a01a504dcef8b65e58bf0 196 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 5 194 4.8E-40 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS05800 f31d02e4477a01a504dcef8b65e58bf0 196 Gene3D G3DSA:3.40.50.150 9 194 2.1E-49 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05800 f31d02e4477a01a504dcef8b65e58bf0 196 Pfam PF03602 Conserved hypothetical protein 95 11 193 2.4E-45 T 09-03-2017 ARZXY2_RS19830 b972e5a0bc800c6ecc513861b99952f5 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 302 6.3E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19830 b972e5a0bc800c6ecc513861b99952f5 309 Gene3D G3DSA:1.10.3720.10 38 296 1.1E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19830 b972e5a0bc800c6ecc513861b99952f5 309 SUPERFAMILY SSF161098 38 309 7.1E-70 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 SMART SM01400 12 128 2.2E-64 T 09-03-2017 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 09-03-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 Gene3D G3DSA:3.40.50.2020 9 167 1.0E-68 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 44.745 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 Gene3D G3DSA:3.40.50.2020 168 295 6.2E-47 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 213 322 1.4E-21 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 323 8.8E-116 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 13 128 1.5E-42 T 09-03-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 ARZXY2_RS12770 5361493d33f76ff1817a834b97f40f45 326 SUPERFAMILY SSF53271 77 314 1.31E-59 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS16865 e7a5a58b7a3a5f5cb580248659a59800 451 Pfam PF04286 Protein of unknown function (DUF445) 86 448 3.8E-104 T 09-03-2017 IPR007383 Protein of unknown function DUF445 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 Gene3D G3DSA:3.20.20.70 2 356 8.4E-123 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 350 46.055 T 09-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 306 326 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 SUPERFAMILY SSF51395 4 352 1.83E-95 T 09-03-2017 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 Pfam PF01180 Dihydroorotate dehydrogenase 50 352 5.3E-92 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 ARZXY2_RS08360 e6fa4e08ba2a111754813199a7430f1a 359 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 355 5.6E-122 T 09-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS03965 6d43f5d80f6d43d14ffb29694a7dc398 200 SUPERFAMILY SSF100950 3 198 4.19E-36 T 09-03-2017 ARZXY2_RS03965 6d43f5d80f6d43d14ffb29694a7dc398 200 PIRSF PIRSF006806 1 195 1.4E-24 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase ARZXY2_RS03965 6d43f5d80f6d43d14ffb29694a7dc398 200 Gene3D G3DSA:3.40.50.10420 4 198 1.4E-42 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain ARZXY2_RS03965 6d43f5d80f6d43d14ffb29694a7dc398 200 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 192 3.6E-32 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase ARZXY2_RS03965 6d43f5d80f6d43d14ffb29694a7dc398 200 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 192 6.3E-32 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase ARZXY2_RS14085 8ca6cc1b1de7b5e992c432c4c2802973 320 Gene3D G3DSA:3.20.20.70 44 294 3.2E-32 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS14085 8ca6cc1b1de7b5e992c432c4c2802973 320 SUPERFAMILY SSF51569 42 282 6.59E-33 T 09-03-2017 ARZXY2_RS00350 815029bd8e92a885ade826e8ef331f2f 160 Pfam PF02080 TrkA-C domain 89 157 3.3E-15 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS00350 815029bd8e92a885ade826e8ef331f2f 160 PIRSF PIRSF005028 1 160 2.8E-59 T 09-03-2017 IPR026278 Potassium/proton antiporter subunit KhtT ARZXY2_RS00350 815029bd8e92a885ade826e8ef331f2f 160 SUPERFAMILY SSF116726 84 157 4.58E-16 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS00350 815029bd8e92a885ade826e8ef331f2f 160 Gene3D G3DSA:3.30.70.1450 87 156 5.8E-18 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 Gene3D G3DSA:1.10.10.60 275 320 3.1E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 SUPERFAMILY SSF46689 272 322 2.82E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 Pfam PF14525 AraC-binding-like domain 24 202 5.1E-32 T 09-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 SUPERFAMILY SSF46689 220 269 1.49E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 Gene3D G3DSA:1.10.10.60 218 274 5.9E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 Pfam PF12833 Helix-turn-helix domain 242 324 3.2E-23 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 273 318 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS17465 73998688e58dc3e8d7f9b788d8a3d5a1 324 SMART SM00342 236 322 3.9E-26 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 Pfam PF12802 MarR family 48 106 2.1E-10 T 09-03-2017 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 SMART SM00347 38 142 2.7E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 2.6E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 2.6E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 2.6E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 2.6E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 SUPERFAMILY SSF46785 25 159 5.86E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 Gene3D G3DSA:1.10.10.10 26 158 1.5E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19720 9d35b843003e0a7338bea8398bc97cbc 162 ProSitePatterns PS01117 MarR-type HTH domain signature. 81 115 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site ARZXY2_RS12485 567870cc3fb5b3a81acb24ea0ff64af3 78 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 16 73 1.5E-16 T 09-03-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 32 517 3.5E-195 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 SUPERFAMILY SSF51735 21 221 7.09E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 31 517 86.377 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 220 516 4.1E-110 T 09-03-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 208 214 - T 09-03-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 Gene3D G3DSA:3.30.360.10 218 516 2.0E-118 T 09-03-2017 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 Gene3D G3DSA:3.40.50.720 30 217 1.8E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PIRSF PIRSF000110 10 518 8.0E-176 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 35 218 3.9E-62 T 09-03-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 SUPERFAMILY SSF55347 208 516 8.5E-113 T 09-03-2017 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 268 284 4.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 357 383 4.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 174 187 4.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 198 226 4.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS09045 946d01e9f1829d131fa815755a059413 518 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 250 267 4.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS15490 60d76187394f0cd2c1ea70db8c0503cb 460 SUPERFAMILY SSF103473 21 433 1.31E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15490 60d76187394f0cd2c1ea70db8c0503cb 460 Pfam PF07690 Major Facilitator Superfamily 50 386 1.0E-26 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS15490 60d76187394f0cd2c1ea70db8c0503cb 460 Gene3D G3DSA:1.20.1250.20 23 225 1.8E-18 T 09-03-2017 ARZXY2_RS15490 60d76187394f0cd2c1ea70db8c0503cb 460 Gene3D G3DSA:1.20.1250.20 248 433 3.6E-19 T 09-03-2017 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 Gene3D G3DSA:3.20.20.70 2 338 8.6E-119 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 5.6E-125 T 09-03-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 PIRSF PIRSF001359 6 338 4.9E-65 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 SUPERFAMILY SSF51569 5 337 6.15E-96 T 09-03-2017 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 Pfam PF01116 Fructose-bisphosphate aldolase class-II 10 337 3.3E-81 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS16150 37cffad95ee4a6d1b38b420b412c338b 339 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 337 2.6E-70 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 Gene3D G3DSA:1.20.1080.10 172 230 2.8E-6 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 Gene3D G3DSA:1.20.1080.10 4 171 1.9E-28 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 PRINTS PR00783 Major intrinsic protein family signature 52 76 2.5E-14 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 PRINTS PR00783 Major intrinsic protein family signature 136 154 2.5E-14 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 PRINTS PR00783 Major intrinsic protein family signature 10 29 2.5E-14 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 Pfam PF00230 Major intrinsic protein 4 172 7.8E-19 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS17695 45b2a908dce57d39185ad5df208649c8 245 SUPERFAMILY SSF81338 5 225 8.29E-35 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS01100 ed989e0babbb1894c496c70b73b3e336 74 Pfam PF11273 Protein of unknown function (DUF3073) 2 63 2.3E-21 T 09-03-2017 IPR021426 Protein of unknown function DUF3073 ARZXY2_RS13200 3c96cdce74c199c63d6cfb871f64fa72 377 SUPERFAMILY SSF53448 16 298 1.72E-52 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS13200 3c96cdce74c199c63d6cfb871f64fa72 377 Pfam PF00483 Nucleotidyl transferase 18 299 6.5E-41 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ARZXY2_RS13200 3c96cdce74c199c63d6cfb871f64fa72 377 Gene3D G3DSA:3.90.550.10 15 288 3.7E-78 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS13200 3c96cdce74c199c63d6cfb871f64fa72 377 SUPERFAMILY SSF159283 315 369 6.67E-14 T 09-03-2017 ARZXY2_RS13200 3c96cdce74c199c63d6cfb871f64fa72 377 Pfam PF01050 Mannose-6-phosphate isomerase 336 374 2.2E-5 T 09-03-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 705 7.0E-131 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 124 198 1.1E-28 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 302 376 1.1E-28 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 SUPERFAMILY SSF56003 127 767 1.23E-152 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 SUPERFAMILY SSF54665 13 136 1.57E-40 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 SMART SM01008 29 135 5.2E-45 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 135 1.2E-28 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 457 581 1.1E-33 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 199 299 5.4E-28 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 378 456 1.1E-51 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.30.365.10 622 767 1.1E-51 T 09-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 ARZXY2_RS09600 764d361afa0761835a5da0bb665810e2 779 Gene3D G3DSA:3.90.1170.50 12 123 2.5E-40 T 09-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead ARZXY2_RS19375 2d561f16050b7e90ab12140fb08af681 91 Pfam PF12728 Helix-turn-helix domain 22 70 5.7E-12 T 09-03-2017 ARZXY2_RS19375 2d561f16050b7e90ab12140fb08af681 91 SUPERFAMILY SSF46955 22 65 6.41E-6 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS19375 2d561f16050b7e90ab12140fb08af681 91 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 22 65 1.3E-10 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS19375 2d561f16050b7e90ab12140fb08af681 91 Gene3D G3DSA:1.10.260.40 23 48 4.4E-4 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Gene3D G3DSA:3.90.180.10 1 180 9.3E-48 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Gene3D G3DSA:3.40.50.720 181 255 3.4E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Gene3D G3DSA:3.40.50.720 290 331 3.4E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Pfam PF00107 Zinc-binding dehydrogenase 189 255 2.8E-9 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 SUPERFAMILY SSF51735 156 350 1.51E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 5.1E-10 T 09-03-2017 IPR027399 Alcohol dehydrogenase GroES-associated ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 4.1E-28 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS13850 501f293f81bd4137d2e19f586a124054 391 SUPERFAMILY SSF50129 1 188 1.05E-57 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS02150 fa1ea9b47a93a705665289590061769a 202 Pfam PF00578 AhpC/TSA family 74 180 1.7E-17 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS02150 fa1ea9b47a93a705665289590061769a 202 SUPERFAMILY SSF52833 69 201 2.55E-30 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS02150 fa1ea9b47a93a705665289590061769a 202 Gene3D G3DSA:3.40.30.10 17 202 1.4E-38 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 Gene3D G3DSA:3.40.50.720 398 672 2.3E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 Gene3D G3DSA:3.40.225.10 4 208 9.2E-30 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 6 677 0.0 T 09-03-2017 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 493 504 5.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 567 586 5.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 547 555 5.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 493 504 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 541 557 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 567 586 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 588 605 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 420 437 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 635 655 4.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 SUPERFAMILY SSF51735 419 671 1.39E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 SMART SM01007 7 209 5.9E-32 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 207 9.0E-23 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 425 671 4.6E-51 T 09-03-2017 ARZXY2_RS00200 591f3dd783ed04d8646fa4f93153e6c0 677 SUPERFAMILY SSF53639 3 210 2.75E-30 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 85 275 1.5E-38 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 Gene3D G3DSA:2.10.109.10 230 283 1.2E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 Gene3D G3DSA:2.10.109.10 98 192 1.2E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 ProSitePatterns PS00761 Signal peptidases I signature 3. 235 248 - T 09-03-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 Pfam PF00717 Peptidase S24-like 107 149 1.6E-7 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 230 249 6.6E-22 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 101 117 6.6E-22 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 182 194 6.6E-22 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 Pfam PF10502 Signal peptidase, peptidase S26 181 267 1.8E-7 T 09-03-2017 IPR019533 Peptidase S26 ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 SUPERFAMILY SSF51306 100 147 3.98E-45 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS07035 2773073e4c1e76086aad81b831e8b77c 298 SUPERFAMILY SSF51306 177 281 3.98E-45 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 SUPERFAMILY SSF53671 7 315 1.31E-98 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 314 7.5E-116 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 8 315 76.639 T 09-03-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 3.9E-24 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 3.9E-24 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 302 3.9E-24 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 3.9E-24 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 Gene3D G3DSA:3.40.50.1370 6 148 3.5E-50 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 312 1.8E-55 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 3.4E-29 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 231 241 3.4E-29 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 3.4E-29 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 3.4E-29 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 293 304 3.4E-29 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 Gene3D G3DSA:3.40.50.1370 149 301 2.3E-64 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS11210 16ce49c427405a0d875007756fffa6cc 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 151 2.8E-43 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 29 530 31.015 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Gene3D G3DSA:3.40.1390.10 39 131 3.8E-21 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Gene3D G3DSA:3.90.190.20 375 523 1.0E-44 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Pfam PF02875 Mur ligase family, glutamate ligase domain 372 455 3.1E-19 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 SUPERFAMILY SSF53244 372 532 1.39E-39 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 143 167 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Pfam PF01225 Mur ligase family, catalytic domain 51 127 7.4E-12 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 51 530 2.1E-130 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Pfam PF08245 Mur ligase middle domain 145 347 2.2E-46 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 SUPERFAMILY SSF63418 39 131 1.96E-19 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 Gene3D G3DSA:3.40.1190.10 140 367 2.7E-72 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10870 760806dcf605ed5504243e0150f23c24 545 SUPERFAMILY SSF53623 140 366 1.72E-68 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 13 502 81.622 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 489 6.9E-152 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 304 316 - T 09-03-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SUPERFAMILY SSF54631 69 211 4.17E-28 T 09-03-2017 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 PIRSF PIRSF000130 4 502 2.0E-197 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SMART SM00116 165 213 5.3E-6 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SMART SM00116 101 149 2.2E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 Pfam PF00571 CBS domain 98 143 2.3E-9 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 Pfam PF00571 CBS domain 157 211 6.7E-4 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 13 470 2.3E-177 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SUPERFAMILY SSF51412 224 493 8.77E-114 T 09-03-2017 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SUPERFAMILY SSF51412 12 95 8.77E-114 T 09-03-2017 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 Gene3D G3DSA:3.20.20.70 12 501 2.3E-190 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS03895 71c49a68b73bf3dd8837a946c39e9463 502 SMART SM01240 12 489 9.0E-302 T 09-03-2017 ARZXY2_RS13060 c48a9c88b8ed9f0e416869208578afed 425 Pfam PF13620 Carboxypeptidase regulatory-like domain 36 87 1.9E-8 T 09-03-2017 ARZXY2_RS13060 c48a9c88b8ed9f0e416869208578afed 425 Pfam PF02653 Branched-chain amino acid transport system / permease component 142 410 3.0E-36 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS13060 c48a9c88b8ed9f0e416869208578afed 425 SUPERFAMILY SSF49464 36 87 1.06E-5 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 SMART SM00937 63 177 1.4E-55 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 Pfam PF03462 PCRF domain 10 202 1.6E-65 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 Pfam PF00472 RF-1 domain 212 320 9.2E-41 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 Gene3D G3DSA:1.20.58.410 5 88 4.3E-16 T 09-03-2017 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 37.408 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 Gene3D G3DSA:3.30.160.20 210 284 1.0E-33 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 SUPERFAMILY SSF75620 8 352 1.57E-126 T 09-03-2017 ARZXY2_RS05190 bce7588c0aabc99ea86a13d7b0f62a1e 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 1.8E-146 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 ARZXY2_RS20615 ecf15b1a9598c97d29d1e4d76f3a21ec 55 Pfam PF00471 Ribosomal protein L33 10 55 5.3E-17 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS20615 ecf15b1a9598c97d29d1e4d76f3a21ec 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 55 14.518 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS20615 ecf15b1a9598c97d29d1e4d76f3a21ec 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 09-03-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS20615 ecf15b1a9598c97d29d1e4d76f3a21ec 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.4E-22 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS20615 ecf15b1a9598c97d29d1e4d76f3a21ec 55 SUPERFAMILY SSF57829 3 55 7.94E-18 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 ARZXY2_RS17000 00c12815995f663fc01976393f675d38 112 Gene3D G3DSA:3.30.70.900 1 100 2.5E-17 T 09-03-2017 ARZXY2_RS17000 00c12815995f663fc01976393f675d38 112 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 90 1.8E-13 T 09-03-2017 IPR009799 EthD domain ARZXY2_RS17000 00c12815995f663fc01976393f675d38 112 Pfam PF09448 Methylmuconolactone methyl-isomerase 1 99 1.1E-15 T 09-03-2017 IPR018566 4-Methylmuconolactone methyl-isomerase ARZXY2_RS17000 00c12815995f663fc01976393f675d38 112 SUPERFAMILY SSF54909 1 101 6.08E-25 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 Pfam PF00696 Amino acid kinase family 23 251 2.7E-56 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 22 434 2.2E-125 T 09-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 SUPERFAMILY SSF53633 24 264 3.01E-76 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 SUPERFAMILY SSF55021 360 435 1.14E-23 T 09-03-2017 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 Pfam PF01842 ACT domain 295 355 4.4E-8 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 PIRSF PIRSF000726 77 441 1.8E-124 T 09-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 ProSitePatterns PS00324 Aspartokinase signature. 25 33 - T 09-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 Gene3D G3DSA:3.40.1160.10 21 265 2.1E-73 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 SUPERFAMILY SSF55021 277 356 1.49E-15 T 09-03-2017 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 84 433 5.0E-115 T 09-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 ARZXY2_RS15815 f87f206e56347fca17b3108d2e631745 448 Pfam PF13840 ACT domain 368 429 3.5E-12 T 09-03-2017 IPR027795 GATS-like ACT domain ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 SUPERFAMILY SSF51366 10 257 5.18E-79 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 Pfam PF00290 Tryptophan synthase alpha chain 15 246 4.2E-70 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 16 246 1.1E-67 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 262 32.393 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 Gene3D G3DSA:3.20.20.70 10 264 3.1E-91 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10260 8217858ffc300d3c503e56c25086865c 270 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 53 66 - T 09-03-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10555 b58e687ef62c4cfb82fd25bfdedec48d 178 SUPERFAMILY SSF51283 31 171 7.2E-49 T 09-03-2017 IPR029054 dUTPase-like ARZXY2_RS10555 b58e687ef62c4cfb82fd25bfdedec48d 178 Pfam PF00692 dUTPase 42 171 8.4E-33 T 09-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 ARZXY2_RS10555 b58e687ef62c4cfb82fd25bfdedec48d 178 Gene3D G3DSA:2.70.40.10 30 171 1.4E-56 T 09-03-2017 IPR029054 dUTPase-like ARZXY2_RS10555 b58e687ef62c4cfb82fd25bfdedec48d 178 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 30 172 32.058 T 09-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 ARZXY2_RS10555 b58e687ef62c4cfb82fd25bfdedec48d 178 TIGRFAM TIGR00576 dut: dUTP diphosphatase 33 171 1.2E-49 T 09-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 Pfam PF00152 tRNA synthetases class II (D, K and N) 168 504 5.7E-63 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 Gene3D G3DSA:2.40.50.140 19 161 6.1E-45 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 506 2.7E-142 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 Pfam PF01336 OB-fold nucleic acid binding domain 72 151 5.2E-8 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 268 285 5.9E-33 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 221 237 5.9E-33 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 205 215 5.9E-33 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 250 263 5.9E-33 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 PRINTS PR00982 Lysyl-tRNA synthetase signature 390 406 5.9E-33 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 24 507 34.288 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 SUPERFAMILY SSF50249 17 161 3.18E-34 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 Gene3D G3DSA:3.30.930.10 166 502 1.2E-103 T 09-03-2017 ARZXY2_RS17860 231a21cc00391f55482a3c7481d86c8f 509 SUPERFAMILY SSF55681 168 505 1.19E-98 T 09-03-2017 ARZXY2_RS17315 ee4f5c26ab15a8d2124bcb0059285819 496 Pfam PF00171 Aldehyde dehydrogenase family 4 431 4.0E-43 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17315 ee4f5c26ab15a8d2124bcb0059285819 496 SUPERFAMILY SSF53720 3 481 6.41E-81 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17315 ee4f5c26ab15a8d2124bcb0059285819 496 Gene3D G3DSA:3.40.605.10 4 229 4.5E-38 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17315 ee4f5c26ab15a8d2124bcb0059285819 496 Gene3D G3DSA:3.40.309.10 230 419 1.2E-43 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 29 348 2.1E-102 T 09-03-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Pfam PF00589 Phage integrase family 138 333 1.6E-44 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 114 1.4E-15 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Gene3D G3DSA:1.10.150.130 24 124 4.3E-25 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 SUPERFAMILY SSF56349 132 346 1.53E-52 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 25 348 52.68 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Gene3D G3DSA:1.10.443.10 137 341 2.6E-55 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 SUPERFAMILY SSF47823 26 123 4.12E-14 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal ARZXY2_RS11105 979a43c2366beac09e867d71596c4f68 350 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 23 348 55.036 T 09-03-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 ARZXY2_RS15945 a3d43aa063eb4c7317c250a3224c01c0 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 289 3.1E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15945 a3d43aa063eb4c7317c250a3224c01c0 297 Gene3D G3DSA:1.10.3720.10 30 285 3.4E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15945 a3d43aa063eb4c7317c250a3224c01c0 297 SUPERFAMILY SSF161098 28 297 6.07E-69 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 Gene3D G3DSA:3.40.50.200 39 346 1.3E-68 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 SUPERFAMILY SSF52743 44 347 1.28E-67 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 287 297 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 63 74 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 Pfam PF00082 Subtilase family 58 337 9.7E-36 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 7.9E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 286 302 7.9E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS13105 49cc08112d398ce8ef64855cddcab6e1 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 101 114 7.9E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS08855 2f8d8b4aac1e570532365ea84c78f590 283 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 83 7.4E-21 T 09-03-2017 IPR013589 Bacterial transglutaminase-like, N-terminal ARZXY2_RS08855 2f8d8b4aac1e570532365ea84c78f590 283 SMART SM00460 171 238 9.6E-15 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS08855 2f8d8b4aac1e570532365ea84c78f590 283 Gene3D G3DSA:3.90.260.10 173 242 1.3E-8 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS08855 2f8d8b4aac1e570532365ea84c78f590 283 Pfam PF01841 Transglutaminase-like superfamily 139 236 2.1E-21 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS08855 2f8d8b4aac1e570532365ea84c78f590 283 SUPERFAMILY SSF54001 8 264 1.07E-35 T 09-03-2017 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 236 251 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 252 271 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 290 309 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 271 290 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 3.6E-61 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Gene3D G3DSA:2.60.120.10 254 289 2.3E-60 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Gene3D G3DSA:2.60.120.10 6 140 2.3E-60 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Pfam PF01238 Phosphomannose isomerase type I 2 367 1.2E-71 T 09-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 126 134 - T 09-03-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 PIRSF PIRSF001480 1 411 4.2E-98 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Gene3D G3DSA:2.60.120.10 302 389 2.4E-13 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 396 1.8E-72 T 09-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Gene3D G3DSA:1.10.441.10 290 301 3.0E-20 T 09-03-2017 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 Gene3D G3DSA:1.10.441.10 141 247 3.0E-20 T 09-03-2017 ARZXY2_RS12935 ff015e1f9b44afddf03e87e46fbe3d27 416 SUPERFAMILY SSF51182 2 387 2.41E-89 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SUPERFAMILY SSF52540 400 606 3.42E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SUPERFAMILY SSF81767 231 350 2.49E-42 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Pfam PF01043 SecA preprotein cross-linking domain 232 340 1.8E-35 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 830 19.594 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 358 375 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 321 343 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 395 408 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 62 86 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 169 189 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 116 126 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 PRINTS PR00906 SecA protein signature 100 114 6.4E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Gene3D G3DSA:3.40.50.300 400 607 1.8E-90 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SMART SM00958 228 340 4.1E-61 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SUPERFAMILY SSF81886 616 838 1.11E-66 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Gene3D G3DSA:3.40.50.300 351 398 1.4E-119 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Gene3D G3DSA:3.40.50.300 3 227 1.4E-119 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Gene3D G3DSA:3.90.1440.10 232 350 2.8E-46 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SMART SM00957 5 384 1.9E-276 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Pfam PF07517 SecA DEAD-like domain 6 383 7.1E-129 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 ProSitePatterns PS01312 SecA family signature. 482 497 - T 09-03-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 816 0.0 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Gene3D G3DSA:1.10.3060.10 644 828 1.0E-52 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 Pfam PF07516 SecA Wing and Scaffold domain 614 827 6.6E-60 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SUPERFAMILY SSF52540 350 397 1.36E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04780 5de0780b5bce763d6b6f8d43e8fe6857 913 SUPERFAMILY SSF52540 5 227 1.36E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Gene3D G3DSA:2.170.190.11 49 147 7.4E-21 T 09-03-2017 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Gene3D G3DSA:2.40.340.10 336 404 1.4E-15 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 SUPERFAMILY SSF63882 12 180 4.45E-41 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 321 5.3E-29 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Gene3D G3DSA:3.40.980.10 169 335 1.9E-49 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 17 173 3.7E-33 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 SUPERFAMILY SSF63867 333 404 4.58E-15 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Pfam PF03454 MoeA C-terminal region (domain IV) 338 404 1.1E-13 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 SMART SM00852 186 325 1.1E-32 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Pfam PF00994 Probable molybdopterin binding domain 188 322 3.4E-20 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Gene3D G3DSA:3.90.105.10 25 48 8.2E-19 T 09-03-2017 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 Gene3D G3DSA:3.90.105.10 148 168 8.2E-19 T 09-03-2017 ARZXY2_RS11465 dceade60250879df88de502403c1de77 404 SUPERFAMILY SSF53218 183 328 2.22E-34 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Gene3D G3DSA:3.90.190.20 356 510 7.4E-44 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Pfam PF08245 Mur ligase middle domain 149 334 1.6E-21 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 SUPERFAMILY SSF53623 143 352 4.32E-45 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Gene3D G3DSA:3.40.50.720 26 126 6.4E-16 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Gene3D G3DSA:3.40.1190.10 127 352 1.1E-58 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 31 511 1.8E-117 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 30 46 8.6E-7 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 304 321 8.6E-7 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 235 252 8.6E-7 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 145 161 8.6E-7 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 SUPERFAMILY SSF51984 26 127 5.1E-13 T 09-03-2017 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 SUPERFAMILY SSF53244 356 513 1.97E-37 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 30 513 31.831 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 147 170 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Pfam PF02875 Mur ligase family, glutamate ligase domain 356 425 2.9E-10 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10855 01f6fd6f073591839655967492935085 523 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 31 70 3.4E-5 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS10005 454a9914ad8eb56e345ec43cac8fb1d5 331 Pfam PF01522 Polysaccharide deacetylase 136 252 1.5E-27 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS10005 454a9914ad8eb56e345ec43cac8fb1d5 331 Gene3D G3DSA:3.20.20.370 128 328 7.5E-50 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS10005 454a9914ad8eb56e345ec43cac8fb1d5 331 SUPERFAMILY SSF88713 118 328 1.51E-49 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS05920 81a36def57ea59090a9d6f52231da998 99 Pfam PF13834 Domain of unknown function (DUF4193) 2 98 5.3E-31 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 ProSitePatterns PS00217 Sugar transport proteins signature 2. 174 199 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 Pfam PF00083 Sugar (and other) transporter 69 487 3.2E-41 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 Gene3D G3DSA:1.20.1250.20 84 264 1.2E-23 T 09-03-2017 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 Gene3D G3DSA:1.20.1250.20 298 485 8.1E-24 T 09-03-2017 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 ProSitePatterns PS00216 Sugar transport proteins signature 1. 355 372 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS17305 fcda32c4c4492dae015f05f203c65600 540 SUPERFAMILY SSF103473 53 487 2.49E-70 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS10020 6244e4a30d7146a6fd73c0e73da85b45 323 SUPERFAMILY SSF52540 10 234 4.89E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10020 6244e4a30d7146a6fd73c0e73da85b45 323 Pfam PF00005 ABC transporter 31 173 7.4E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS10020 6244e4a30d7146a6fd73c0e73da85b45 323 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS10020 6244e4a30d7146a6fd73c0e73da85b45 323 SMART SM00382 39 221 1.3E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS10020 6244e4a30d7146a6fd73c0e73da85b45 323 Gene3D G3DSA:3.40.50.300 11 236 1.2E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 Gene3D G3DSA:1.10.1660.10 10 63 1.4E-22 T 09-03-2017 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 ProSitePatterns PS00552 MerR-type HTH domain signature. 13 35 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 Pfam PF00376 MerR family regulatory protein 11 47 5.3E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 146 3.6E-63 T 09-03-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 SUPERFAMILY SSF46955 10 131 1.03E-30 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 SMART SM00422 10 78 1.0E-27 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 Gene3D G3DSA:1.10.1660.10 64 140 1.6E-18 T 09-03-2017 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 Pfam PF09278 MerR, DNA binding 52 117 2.7E-19 T 09-03-2017 IPR015358 Transcription regulator MerR, DNA binding ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 6.0E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 6.0E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01000 4800c1afce7410d7fe6ca1bf6de87611 151 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 6.0E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS10605 056dbe4b328c9bedaf77b09509fe43e0 172 SUPERFAMILY SSF109854 17 170 4.58E-25 T 09-03-2017 ARZXY2_RS10605 056dbe4b328c9bedaf77b09509fe43e0 172 Gene3D G3DSA:1.20.120.450 51 170 1.2E-14 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase ARZXY2_RS10605 056dbe4b328c9bedaf77b09509fe43e0 172 Pfam PF12867 DinB superfamily 52 166 8.5E-6 T 09-03-2017 IPR024775 DinB-like domain ARZXY2_RS02495 15c80ab6c7039b2a5e2b3b314eeb5908 209 SUPERFAMILY SSF53448 2 153 1.69E-17 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02495 15c80ab6c7039b2a5e2b3b314eeb5908 209 Gene3D G3DSA:3.90.550.10 2 158 1.5E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS15765 ca086a8c1cc4941d4a3bdaf8d36d8515 534 SUPERFAMILY SSF51261 116 250 1.46E-43 T 09-03-2017 IPR011055 Duplicated hybrid motif ARZXY2_RS15765 ca086a8c1cc4941d4a3bdaf8d36d8515 534 Gene3D G3DSA:2.70.70.10 120 250 1.0E-38 T 09-03-2017 ARZXY2_RS15765 ca086a8c1cc4941d4a3bdaf8d36d8515 534 Pfam PF01551 Peptidase family M23 152 247 1.1E-26 T 09-03-2017 IPR016047 Peptidase M23 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 SMART SM00917 439 574 1.8E-33 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 11 575 1.6E-254 T 09-03-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 SUPERFAMILY SSF51569 29 337 1.39E-97 T 09-03-2017 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 Pfam PF00682 HMGL-like 40 320 2.8E-75 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 Gene3D G3DSA:3.20.20.70 21 411 1.5E-145 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 47 63 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 12 575 54.051 T 09-03-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 SUPERFAMILY SSF110921 469 573 2.09E-33 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 Pfam PF08502 LeuA allosteric (dimerisation) domain 439 573 2.1E-29 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 ARZXY2_RS08330 c1c5c213e94cfa5d5a5a9522ae252740 579 SUPERFAMILY SSF89000 405 454 2.86E-14 T 09-03-2017 ARZXY2_RS16065 9ad952af4cdacb15e162d7077b32a4b1 454 Pfam PF07690 Major Facilitator Superfamily 35 397 1.6E-27 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS16065 9ad952af4cdacb15e162d7077b32a4b1 454 SUPERFAMILY SSF103473 27 451 3.79E-62 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16065 9ad952af4cdacb15e162d7077b32a4b1 454 Gene3D G3DSA:1.20.1250.20 32 230 2.0E-21 T 09-03-2017 ARZXY2_RS16065 9ad952af4cdacb15e162d7077b32a4b1 454 Gene3D G3DSA:1.20.1250.20 254 445 1.1E-16 T 09-03-2017 ARZXY2_RS00480 fb3c6a659a7132e208072123bf0e4ba6 500 PIRSF PIRSF006060 21 498 1.5E-81 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS00480 fb3c6a659a7132e208072123bf0e4ba6 500 ProSitePatterns PS00218 Amino acid permeases signature. 70 101 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS00480 fb3c6a659a7132e208072123bf0e4ba6 500 Pfam PF00324 Amino acid permease 45 480 1.1E-113 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 Pfam PF13377 Periplasmic binding protein-like domain 178 334 1.6E-27 T 09-03-2017 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 2.3E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 SMART SM00354 11 81 1.3E-22 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 Gene3D G3DSA:3.40.50.2300 64 183 2.8E-38 T 09-03-2017 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 SUPERFAMILY SSF53822 71 337 9.58E-64 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 SUPERFAMILY SSF47413 11 69 1.15E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 Gene3D G3DSA:1.10.260.40 12 63 2.2E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16925 b020829b4175ef4db5405a71b5b83871 341 Gene3D G3DSA:3.40.50.2300 184 312 3.2E-37 T 09-03-2017 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:3.40.50.300 368 480 1.7E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:3.40.50.300 492 552 1.5E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:3.40.50.300 11 70 1.7E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:3.40.50.300 679 792 1.5E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 SUPERFAMILY SSF52540 500 768 1.61E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 SUPERFAMILY SSF52540 306 457 4.9E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 SUPERFAMILY SSF52540 23 71 4.9E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Pfam PF00005 ABC transporter 508 715 1.0E-13 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 SMART SM00382 42 454 10.0 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 SMART SM00382 517 761 0.054 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:1.20.1580.10 556 678 2.8E-35 T 09-03-2017 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:1.20.1580.10 111 188 3.3E-33 T 09-03-2017 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:1.20.1580.10 302 367 3.3E-33 T 09-03-2017 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 Gene3D G3DSA:1.10.8.280 191 301 1.4E-7 T 09-03-2017 ARZXY2_RS08540 4c4d4b4ec61d0a2bef26bc2637964382 797 ProSitePatterns PS00211 ABC transporters family signature. 688 702 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 SUPERFAMILY SSF52833 3 107 2.34E-34 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 9.2E-36 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 PIRSF PIRSF000077 1 107 1.0E-39 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 PRINTS PR00421 Thioredoxin family signature 71 82 1.3E-6 T 09-03-2017 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 PRINTS PR00421 Thioredoxin family signature 23 31 1.3E-6 T 09-03-2017 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 PRINTS PR00421 Thioredoxin family signature 31 40 1.3E-6 T 09-03-2017 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 Pfam PF00085 Thioredoxin 6 100 2.1E-27 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 ARZXY2_RS18610 a520853b1b403ad14482a5f3d494617e 108 Gene3D G3DSA:3.40.30.10 3 104 1.2E-33 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 Pfam PF00296 Luciferase-like monooxygenase 23 386 2.9E-58 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 PIRSF PIRSF000337 4 445 2.3E-162 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 430 2.1E-168 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 SUPERFAMILY SSF51679 5 436 3.53E-130 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 Gene3D G3DSA:3.20.20.30 4 306 1.6E-137 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS12385 cafc0e6b7047ee8d087a6cf02d5183a5 455 Gene3D G3DSA:3.20.20.30 348 436 1.6E-137 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS16185 d13590d2399453e7674d5ff0732e53da 143 SUPERFAMILY SSF88723 8 120 1.34E-12 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS16185 d13590d2399453e7674d5ff0732e53da 143 Gene3D G3DSA:3.40.50.1010 8 115 8.3E-7 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS16185 d13590d2399453e7674d5ff0732e53da 143 Pfam PF01850 PIN domain 8 121 2.0E-12 T 09-03-2017 IPR002716 PIN domain ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 Gene3D G3DSA:1.20.1640.10 589 813 8.3E-35 T 09-03-2017 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 Gene3D G3DSA:1.20.1640.10 239 437 2.9E-27 T 09-03-2017 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 Pfam PF03176 MMPL family 45 444 6.8E-46 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 Pfam PF03176 MMPL family 505 807 7.9E-39 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 SUPERFAMILY SSF82866 219 431 7.72E-26 T 09-03-2017 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 PRINTS PR00702 Acriflavin resistance protein family signature 273 296 5.5E-7 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 PRINTS PR00702 Acriflavin resistance protein family signature 326 350 5.5E-7 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 PRINTS PR00702 Acriflavin resistance protein family signature 401 424 5.5E-7 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12515 734184f828b5ac6b86883e3d58de25af 841 SUPERFAMILY SSF82866 565 807 1.01E-30 T 09-03-2017 ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 SUPERFAMILY SSF52172 166 233 1.14E-7 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 Pfam PF03861 ANTAR domain 181 233 3.6E-16 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 SMART SM01012 178 233 7.2E-19 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 Gene3D G3DSA:1.10.10.10 181 237 9.9E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 Gene3D G3DSA:3.30.450.40 15 166 2.2E-10 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 SUPERFAMILY SSF55781 27 177 2.16E-14 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS18130 b7600ddf8efa37c13680af5229b36607 246 PIRSF PIRSF036625 1 244 9.5E-42 T 09-03-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Gene3D G3DSA:3.40.50.980 347 403 7.2E-23 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Gene3D G3DSA:3.40.50.980 198 291 7.2E-23 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Gene3D G3DSA:2.30.38.10 409 473 1.1E-19 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Pfam PF00501 AMP-binding enzyme 41 479 9.8E-86 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 SUPERFAMILY SSF56801 17 296 1.83E-106 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 SUPERFAMILY SSF56801 350 608 1.83E-106 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Gene3D G3DSA:3.30.300.30 477 535 3.1E-5 T 09-03-2017 ARZXY2_RS12850 fe50e5b3e5e8d0bba1b4d83fff1e97ca 610 Gene3D G3DSA:3.40.50.980 55 197 2.3E-28 T 09-03-2017 ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 SUPERFAMILY SSF52402 8 142 3.85E-30 T 09-03-2017 ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 Pfam PF00582 Universal stress protein family 9 142 3.0E-24 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 PRINTS PR01438 Universal stress protein signature 120 142 2.4E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 PRINTS PR01438 Universal stress protein signature 7 25 2.4E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 PRINTS PR01438 Universal stress protein signature 102 114 2.4E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09985 1a08719cbe86084f1267e5cbf8558972 144 Gene3D G3DSA:3.40.50.620 7 142 7.8E-32 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 SUPERFAMILY SSF69742 3 158 1.96E-30 T 09-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 157 1.7E-31 T 09-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 8 414 1.4E-69 T 09-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 PIRSF PIRSF000445 1 428 2.1E-99 T 09-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 181 302 6.3E-12 T 09-03-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 412 20.492 T 09-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 SUPERFAMILY SSF51735 180 306 9.11E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 Gene3D G3DSA:3.40.50.720 165 308 3.9E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 100 123 - T 09-03-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 317 413 1.7E-16 T 09-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS04455 6cab0cc2d8e0135aaea02f68f89026ba 439 SUPERFAMILY SSF69075 316 413 9.02E-12 T 09-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 ARZXY2_RS01280 965c27c52082017821ede2ad875e30b4 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 293 1.8E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01280 965c27c52082017821ede2ad875e30b4 299 SUPERFAMILY SSF161098 30 299 1.21E-73 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01280 965c27c52082017821ede2ad875e30b4 299 Gene3D G3DSA:1.10.3720.10 22 286 6.4E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15580 8b5158dcdfa2b5bfe4dab07c01f283ca 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 3.8E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15580 8b5158dcdfa2b5bfe4dab07c01f283ca 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.9E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15580 8b5158dcdfa2b5bfe4dab07c01f283ca 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.9E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15580 8b5158dcdfa2b5bfe4dab07c01f283ca 204 Gene3D G3DSA:1.10.357.10 19 201 1.3E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS15580 8b5158dcdfa2b5bfe4dab07c01f283ca 204 SUPERFAMILY SSF46689 18 91 2.46E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12685 2d2a41082f78ef3326e4d5f4875f428d 379 Pfam PF13439 Glycosyltransferase Family 4 16 177 3.1E-19 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS12685 2d2a41082f78ef3326e4d5f4875f428d 379 Gene3D G3DSA:3.40.50.2000 185 327 7.6E-29 T 09-03-2017 ARZXY2_RS12685 2d2a41082f78ef3326e4d5f4875f428d 379 SUPERFAMILY SSF53756 9 362 3.14E-75 T 09-03-2017 ARZXY2_RS12685 2d2a41082f78ef3326e4d5f4875f428d 379 Pfam PF00534 Glycosyl transferases group 1 185 329 3.5E-28 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS12685 2d2a41082f78ef3326e4d5f4875f428d 379 ProDom PD149122 TRANSFERASE GUANYLYLTRANSFERASE NUCLEOTIDYLTRANSFERASE CORE-SPIKE LAMBDA-2 MRNA CAPPING VP1 ENZYME 3D-STRUCTURE 152 211 0.002 T 09-03-2017 IPR010311 Reovirus core-spike lambda-2 GO:0004482|GO:0004484|GO:0005524|GO:0006370|GO:0019028 MetaCyc: PWY-7375 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.031 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 SUPERFAMILY SSF54686 1 136 1.26E-55 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 09-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.5E-48 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.9E-40 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.9E-40 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.9E-40 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.9E-40 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 09-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 3.0E-56 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03530 1690c8bf5ddbd31971b89376de38c046 138 Gene3D G3DSA:3.90.1170.10 23 136 3.0E-53 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS02705 5b94b7968d5d4c550b8f0b9aff30bb5a 299 SMART SM00849 26 215 1.2E-13 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02705 5b94b7968d5d4c550b8f0b9aff30bb5a 299 Pfam PF00753 Metallo-beta-lactamase superfamily 28 215 6.9E-16 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02705 5b94b7968d5d4c550b8f0b9aff30bb5a 299 SUPERFAMILY SSF56281 10 264 1.82E-41 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02705 5b94b7968d5d4c550b8f0b9aff30bb5a 299 Gene3D G3DSA:3.60.15.10 3 235 4.9E-40 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00035 64250fa616a98ed1ebed391ce77340e3 187 SUPERFAMILY SSF55729 18 185 1.78E-40 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS00035 64250fa616a98ed1ebed391ce77340e3 187 Pfam PF13302 Acetyltransferase (GNAT) domain 18 161 7.1E-18 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS00035 64250fa616a98ed1ebed391ce77340e3 187 Gene3D G3DSA:3.40.630.30 17 184 1.8E-42 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS05890 ead33bbc72b2b655010bf83c934b0bc7 279 Pfam PF13683 Integrase core domain 198 263 3.2E-23 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS05890 ead33bbc72b2b655010bf83c934b0bc7 279 Pfam PF13276 HTH-like domain 36 93 3.7E-9 T 09-03-2017 IPR025948 HTH-like domain ARZXY2_RS05890 ead33bbc72b2b655010bf83c934b0bc7 279 SUPERFAMILY SSF53098 112 268 1.39E-33 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS05890 ead33bbc72b2b655010bf83c934b0bc7 279 Gene3D G3DSA:3.30.420.10 105 263 7.0E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS05470 cf1973a6c873adff1f8cad5f4d77be32 218 Gene3D G3DSA:3.40.50.2020 3 68 5.9E-38 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS05470 cf1973a6c873adff1f8cad5f4d77be32 218 Gene3D G3DSA:3.40.50.2020 104 209 5.9E-38 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS05470 cf1973a6c873adff1f8cad5f4d77be32 218 SUPERFAMILY SSF53271 3 215 6.01E-37 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS05470 cf1973a6c873adff1f8cad5f4d77be32 218 Pfam PF00156 Phosphoribosyl transferase domain 14 199 1.9E-18 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 198 213 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 372 390 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 339 354 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 56 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 390 406 6.3E-34 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Pfam PF01494 FAD binding domain 32 405 1.3E-72 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Gene3D G3DSA:3.30.9.10 210 322 1.2E-62 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Gene3D G3DSA:3.30.9.10 387 438 1.2E-62 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 SUPERFAMILY SSF54373 222 322 7.06E-32 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 SUPERFAMILY SSF51905 33 219 7.78E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 SUPERFAMILY SSF51905 316 415 7.78E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Gene3D G3DSA:3.40.30.20 439 630 2.0E-49 T 09-03-2017 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Gene3D G3DSA:3.50.50.60 337 377 5.2E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Gene3D G3DSA:3.50.50.60 30 209 5.2E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 Pfam PF07976 Phenol hydroxylase, C-terminal dimerisation domain 435 593 1.3E-37 T 09-03-2017 IPR012941 Phenol hydroxylase, C-terminal dimerisation domain ARZXY2_RS09315 b303760a2443912e426ffbc4ca1ceb05 658 SUPERFAMILY SSF52833 445 631 2.1E-49 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS01545 c66daf02eef99a2aa613f655fb9ee273 102 Pfam PF04237 YjbR 12 95 3.4E-12 T 09-03-2017 IPR007351 Uncharacterised protein YjbR ARZXY2_RS01545 c66daf02eef99a2aa613f655fb9ee273 102 SUPERFAMILY SSF142906 1 97 4.97E-10 T 09-03-2017 ARZXY2_RS04545 e224c20f63c7b5c4402ea298cdf3030a 426 SUPERFAMILY SSF56112 20 287 3.35E-30 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS04545 e224c20f63c7b5c4402ea298cdf3030a 426 Pfam PF01636 Phosphotransferase enzyme family 41 263 2.8E-20 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase ARZXY2_RS04545 e224c20f63c7b5c4402ea298cdf3030a 426 Gene3D G3DSA:3.90.1200.10 114 280 1.9E-21 T 09-03-2017 ARZXY2_RS13865 67deb85114458c14aaebf7cb4984065b 167 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 6 126 8.2E-39 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 ARZXY2_RS13865 67deb85114458c14aaebf7cb4984065b 167 Pfam PF03852 DNA mismatch endonuclease Vsr 6 81 8.0E-28 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 ARZXY2_RS13865 67deb85114458c14aaebf7cb4984065b 167 PIRSF PIRSF018267 4 150 5.7E-48 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 ARZXY2_RS13865 67deb85114458c14aaebf7cb4984065b 167 SUPERFAMILY SSF52980 6 145 2.2E-45 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS13865 67deb85114458c14aaebf7cb4984065b 167 Gene3D G3DSA:3.40.960.10 24 137 1.7E-44 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 7 89 2.6E-38 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 Pfam PF00312 Ribosomal protein S15 8 88 3.7E-37 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 SUPERFAMILY SSF47060 3 89 1.94E-35 T 09-03-2017 IPR009068 S15/NS1, RNA-binding ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-36 T 09-03-2017 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 Gene3D G3DSA:1.10.287.10 3 89 3.3E-39 T 09-03-2017 IPR009068 S15/NS1, RNA-binding ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 SMART SM01387 8 88 8.2E-53 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11510 cba843014e54dc9627e6f4feb712bf43 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.377 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 SUPERFAMILY SSF50037 151 223 9.61E-6 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 8 64 3.2E-19 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 SMART SM00899 148 225 5.2E-14 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 SUPERFAMILY SSF47979 68 140 2.09E-26 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 SMART SM00529 29 128 6.5E-42 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 Pfam PF04023 FeoA domain 149 224 2.2E-15 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 Gene3D G3DSA:1.10.10.10 6 75 1.7E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 SUPERFAMILY SSF46785 8 67 1.37E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 Gene3D G3DSA:1.10.60.10 78 142 3.2E-31 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS04995 ad39bb042b1c0aeac0febca7dda1de0d 236 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 136 2.6E-30 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS17045 659775e47efa03c4f154c518ecdf2993 255 Gene3D G3DSA:1.20.120.450 25 143 1.4E-6 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase ARZXY2_RS17045 659775e47efa03c4f154c518ecdf2993 255 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 156 3.6E-28 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 ARZXY2_RS17045 659775e47efa03c4f154c518ecdf2993 255 SUPERFAMILY SSF55718 165 254 1.65E-12 T 09-03-2017 IPR003033 SCP2 sterol-binding domain ARZXY2_RS17045 659775e47efa03c4f154c518ecdf2993 255 SUPERFAMILY SSF109854 8 163 4.58E-45 T 09-03-2017 ARZXY2_RS17045 659775e47efa03c4f154c518ecdf2993 255 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 231 1.0E-40 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 Gene3D G3DSA:3.90.1310.10 150 250 2.8E-27 T 09-03-2017 ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 SUPERFAMILY SSF56601 195 587 1.6E-82 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 Pfam PF03717 Penicillin-binding Protein dimerisation domain 63 222 3.9E-15 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 Gene3D G3DSA:3.40.710.10 251 580 1.1E-78 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 SUPERFAMILY SSF56519 61 243 2.75E-36 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ARZXY2_RS10875 724f8477e6df13e059a5408c860ba37c 598 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 574 3.1E-64 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 SUPERFAMILY SSF88659 100 156 6.35E-14 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 Gene3D G3DSA:1.10.10.10 101 156 1.1E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 SUPERFAMILY SSF88946 6 86 1.88E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 156 5.4E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 Pfam PF08281 Sigma-70, region 4 101 150 1.9E-13 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 Gene3D G3DSA:1.10.1740.10 5 79 5.8E-10 T 09-03-2017 ARZXY2_RS17550 3b1f20cd6240fe5f30b4adadcdbec165 169 Pfam PF04542 Sigma-70 region 2 16 77 1.1E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS13880 d941c1b6cf6435483cd15ad58cf85fc8 442 Gene3D G3DSA:1.20.1250.20 247 434 9.7E-6 T 09-03-2017 ARZXY2_RS13880 d941c1b6cf6435483cd15ad58cf85fc8 442 SUPERFAMILY SSF103473 21 439 5.49E-52 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13880 d941c1b6cf6435483cd15ad58cf85fc8 442 Pfam PF07690 Major Facilitator Superfamily 70 385 1.5E-22 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS13880 d941c1b6cf6435483cd15ad58cf85fc8 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 93 109 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS13880 d941c1b6cf6435483cd15ad58cf85fc8 442 Gene3D G3DSA:1.20.1250.20 32 236 3.2E-24 T 09-03-2017 ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1 157 3.0E-32 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 Pfam PF00563 EAL domain 175 412 3.0E-70 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 SUPERFAMILY SSF55073 5 160 1.41E-36 T 09-03-2017 IPR029787 Nucleotide cyclase ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 SMART SM00267 1 158 1.4E-32 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 SUPERFAMILY SSF141868 174 424 8.63E-83 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 Gene3D G3DSA:3.20.20.450 172 425 3.7E-90 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 SMART SM00052 168 417 9.8E-95 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1 154 1.4E-34 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS15920 e13febd7185d3f5c4d1abc3730b4bd16 430 Gene3D G3DSA:3.30.70.270 1 161 5.3E-43 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Gene3D G3DSA:3.40.50.980 102 288 1.9E-40 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Gene3D G3DSA:3.30.300.30 547 673 3.5E-28 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 51 671 3.6E-288 T 09-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Gene3D G3DSA:3.40.50.980 289 453 4.5E-26 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 31 673 49.808 T 09-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 ProSitePatterns PS00455 Putative AMP-binding domain signature. 283 294 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Gene3D G3DSA:2.30.38.10 469 544 1.7E-10 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 SUPERFAMILY SSF56801 55 669 3.14E-171 T 09-03-2017 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Pfam PF13193 AMP-binding enzyme C-terminal domain 560 639 2.8E-28 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 52 104 5.1E-18 T 09-03-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 ARZXY2_RS01790 d1317744415d5f2723178442fbfc1164 675 Pfam PF00501 AMP-binding enzyme 113 551 1.6E-93 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS11045 f6654131e9c3b68ecf62f79c12f66f08 217 Gene3D G3DSA:1.10.10.10 116 189 1.8E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11045 f6654131e9c3b68ecf62f79c12f66f08 217 Gene3D G3DSA:1.10.10.10 17 112 4.8E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11045 f6654131e9c3b68ecf62f79c12f66f08 217 SUPERFAMILY SSF46785 21 111 2.9E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11045 f6654131e9c3b68ecf62f79c12f66f08 217 Pfam PF04079 Segregation and condensation complex subunit ScpB 22 198 6.4E-57 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 ARZXY2_RS11045 f6654131e9c3b68ecf62f79c12f66f08 217 SUPERFAMILY SSF46785 116 189 2.09E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Gene3D G3DSA:3.40.50.300 475 566 1.3E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Gene3D G3DSA:3.40.50.300 284 285 1.3E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Gene3D G3DSA:3.40.50.300 151 247 1.3E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Pfam PF13087 AAA domain 542 723 6.1E-31 T 09-03-2017 ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 SUPERFAMILY SSF52540 426 728 1.22E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 SUPERFAMILY SSF52540 291 305 1.22E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 SUPERFAMILY SSF52540 165 231 1.22E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Pfam PF10881 Protein of unknown function (DUF2726) 784 905 1.1E-11 T 09-03-2017 IPR024402 Domain of unknown function DUF2726 ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Gene3D G3DSA:3.40.50.300 567 725 3.2E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11825 8516fc97ce25c1f88b9f748113eec3c7 908 Pfam PF13086 AAA domain 164 512 1.0E-21 T 09-03-2017 ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 PRINTS PR00069 Aldo-keto reductase signature 144 161 8.1E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 PRINTS PR00069 Aldo-keto reductase signature 113 131 8.1E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 PRINTS PR00069 Aldo-keto reductase signature 47 71 8.1E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 Pfam PF00248 Aldo/keto reductase family 17 315 2.1E-74 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 Gene3D G3DSA:3.20.20.100 9 320 1.0E-105 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08535 96810694197910813fbaeb2b18814650 325 SUPERFAMILY SSF51430 1 320 3.67E-104 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 SUPERFAMILY SSF51338 17 72 1.16E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 SUPERFAMILY SSF51338 479 505 1.16E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 SUPERFAMILY SSF51556 71 128 5.19E-29 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 SUPERFAMILY SSF51556 192 472 5.19E-29 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 Gene3D G3DSA:2.30.40.10 12 80 6.4E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 Gene3D G3DSA:3.20.20.140 81 93 2.2E-25 T 09-03-2017 ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 Gene3D G3DSA:3.20.20.140 194 470 2.2E-25 T 09-03-2017 ARZXY2_RS08600 67d9c84bb69e85de87521f0e2569238c 549 Pfam PF07969 Amidohydrolase family 60 540 3.7E-66 T 09-03-2017 IPR013108 Amidohydrolase 3 ARZXY2_RS14855 8e8bb8616d479f7000933627e98f0492 119 SUPERFAMILY SSF52038 25 112 4.58E-16 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) ARZXY2_RS14855 8e8bb8616d479f7000933627e98f0492 119 Pfam PF01337 Barstar (barnase inhibitor) 31 107 1.1E-11 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) ARZXY2_RS14855 8e8bb8616d479f7000933627e98f0492 119 Gene3D G3DSA:3.30.370.10 31 108 6.2E-14 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) ARZXY2_RS04885 c91cc387cad980129ae4bff032434ef1 318 Pfam PF00535 Glycosyl transferase family 2 9 170 2.8E-18 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS04885 c91cc387cad980129ae4bff032434ef1 318 SUPERFAMILY SSF53448 6 239 7.5E-34 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS04885 c91cc387cad980129ae4bff032434ef1 318 Gene3D G3DSA:3.90.550.10 9 211 5.4E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS04915 0bd0c1c6981da4a2e1a8318e99a1f0c5 407 Gene3D G3DSA:3.40.50.300 170 363 2.1E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04915 0bd0c1c6981da4a2e1a8318e99a1f0c5 407 Pfam PF00437 Type II/IV secretion system protein 71 345 6.7E-57 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 ARZXY2_RS04915 0bd0c1c6981da4a2e1a8318e99a1f0c5 407 SUPERFAMILY SSF52540 56 350 4.18E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04915 0bd0c1c6981da4a2e1a8318e99a1f0c5 407 Gene3D G3DSA:3.30.450.90 67 163 5.7E-28 T 09-03-2017 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Pfam PF00289 Biotin carboxylase, N-terminal domain 20 128 1.5E-42 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 SMART SM00878 361 479 1.0E-42 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Gene3D G3DSA:2.40.50.100 637 702 8.9E-20 T 09-03-2017 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 347 1.2E-70 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 171 185 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Gene3D G3DSA:3.30.1490.20 148 219 5.3E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 SUPERFAMILY SSF51246 356 482 1.36E-30 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 SUPERFAMILY SSF52440 16 131 1.44E-46 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Pfam PF02785 Biotin carboxylase C-terminal domain 361 480 4.3E-29 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Pfam PF00364 Biotin-requiring enzyme 637 702 3.1E-15 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 SUPERFAMILY SSF56059 101 373 2.83E-60 T 09-03-2017 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 SUPERFAMILY SSF51230 634 702 5.1E-18 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 660 677 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 311 318 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Gene3D G3DSA:3.30.470.20 222 482 1.4E-90 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS11700 20a1b8ea0184f8922d34137cd648629b 718 Gene3D G3DSA:3.40.50.20 20 147 1.5E-49 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 SUPERFAMILY SSF103473 484 521 2.35E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 SUPERFAMILY SSF103473 269 441 2.35E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 SUPERFAMILY SSF103473 23 215 2.35E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 Gene3D G3DSA:1.20.1250.20 286 442 3.6E-24 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 Gene3D G3DSA:1.20.1250.20 487 518 3.6E-24 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 Gene3D G3DSA:1.20.1250.20 34 208 5.3E-32 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 Pfam PF07690 Major Facilitator Superfamily 36 431 8.1E-49 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 145 9.5E-11 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 PRINTS PR01036 Tetracycline resistance protein TetB signature 422 441 9.5E-11 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 PRINTS PR01036 Tetracycline resistance protein TetB signature 155 179 9.5E-11 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 PRINTS PR01036 Tetracycline resistance protein TetB signature 221 239 9.5E-11 T 09-03-2017 ARZXY2_RS13970 d5cd2d33c301937d7f9498d367737057 692 PRINTS PR01036 Tetracycline resistance protein TetB signature 34 58 9.5E-11 T 09-03-2017 ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Pfam PF00571 CBS domain 283 336 5.5E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Pfam PF00571 CBS domain 217 267 7.5E-6 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 SMART SM01091 351 431 1.7E-18 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Gene3D G3DSA:3.30.465.10 331 428 2.4E-22 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 SUPERFAMILY SSF56176 352 438 1.23E-16 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Pfam PF01595 Domain of unknown function DUF21 9 199 1.6E-31 T 09-03-2017 IPR002550 Domain of unknown function DUF21 ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 SUPERFAMILY SSF54631 208 346 1.77E-27 T 09-03-2017 ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Pfam PF03471 Transporter associated domain 354 427 1.5E-17 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS05060 48b67d7c0b7f2cd1b50748bcad47a5e6 450 Gene3D G3DSA:3.10.580.10 205 330 2.2E-17 T 09-03-2017 ARZXY2_RS10990 d8fdd8b47e57a341f9c12886d4b6e2c2 158 Gene3D G3DSA:2.60.200.20 53 152 1.3E-28 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS10990 d8fdd8b47e57a341f9c12886d4b6e2c2 158 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 63 147 2.6E-20 T 09-03-2017 IPR032030 YscD, cytoplasmic domain ARZXY2_RS10990 d8fdd8b47e57a341f9c12886d4b6e2c2 158 SMART SM00240 77 127 3.1E-13 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS10990 d8fdd8b47e57a341f9c12886d4b6e2c2 158 SUPERFAMILY SSF49879 28 150 1.51E-31 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 ProSitePatterns PS00622 LuxR-type HTH domain signature. 374 401 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 Gene3D G3DSA:1.10.10.10 360 419 4.5E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 374 390 2.1E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 360 374 2.1E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 390 402 2.1E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 SUPERFAMILY SSF55874 220 345 9.03E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 SUPERFAMILY SSF46894 349 419 8.84E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 Pfam PF00196 Bacterial regulatory proteins, luxR family 360 414 3.5E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18985 6af113abab361684f7523fe62cc27b01 420 SMART SM00421 357 414 1.5E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS08105 2642c346c807bea0f18df4e488a18edc 136 Gene3D G3DSA:1.10.940.10 3 129 1.2E-38 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS08105 2642c346c807bea0f18df4e488a18edc 136 Pfam PF01029 NusB family 6 129 4.4E-32 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS08105 2642c346c807bea0f18df4e488a18edc 136 SUPERFAMILY SSF48013 4 127 9.29E-35 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS08105 2642c346c807bea0f18df4e488a18edc 136 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 132 20.427 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 ARZXY2_RS08105 2642c346c807bea0f18df4e488a18edc 136 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 129 2.5E-35 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 Pfam PF01494 FAD binding domain 8 345 8.3E-70 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 SUPERFAMILY SSF51905 268 368 2.76E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 SUPERFAMILY SSF51905 8 176 2.76E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 SUPERFAMILY SSF54373 179 278 1.69E-38 T 09-03-2017 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 Gene3D G3DSA:3.30.9.10 157 302 9.4E-57 T 09-03-2017 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 Gene3D G3DSA:3.50.50.60 4 156 1.6E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 4.0E-28 T 09-03-2017 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 4.0E-28 T 09-03-2017 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 4.0E-28 T 09-03-2017 ARZXY2_RS19765 aa2fda899cd8d81e7f58ca97356a7f73 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.0E-28 T 09-03-2017 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 Gene3D G3DSA:3.40.50.170 89 281 1.5E-55 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 281 1.1E-98 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 Pfam PF00551 Formyl transferase 87 263 4.9E-37 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PIRSF PIRSF036480 3 282 1.1E-108 T 09-03-2017 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 87 109 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 109 136 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 233 255 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 255 280 1.1E-49 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 281 46.307 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 Gene3D G3DSA:3.30.70.260 4 81 4.8E-27 T 09-03-2017 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 SUPERFAMILY SSF55021 3 83 1.83E-19 T 09-03-2017 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 Pfam PF13740 ACT domain 6 78 2.8E-10 T 09-03-2017 ARZXY2_RS13290 9f6193edd87e4d492185db983c03c752 282 SUPERFAMILY SSF53328 87 282 5.23E-61 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 Pfam PF02355 Protein export membrane protein 124 308 4.2E-46 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 PRINTS PR01755 Bacterial translocase SecF protein signature 242 257 2.4E-16 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 PRINTS PR01755 Bacterial translocase SecF protein signature 47 62 2.4E-16 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 PRINTS PR01755 Bacterial translocase SecF protein signature 207 225 2.4E-16 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 Gene3D G3DSA:1.20.1640.10 107 313 1.5E-18 T 09-03-2017 ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 48 299 3.6E-50 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 19 310 22.386 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 SUPERFAMILY SSF82866 129 308 1.18E-27 T 09-03-2017 ARZXY2_RS07995 c1a4fa5da4a3892b9330e8d757da920e 329 Pfam PF07549 SecD/SecF GG Motif 48 63 7.3E-5 T 09-03-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 SUPERFAMILY SSF53850 90 301 3.46E-24 T 09-03-2017 ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 Gene3D G3DSA:3.40.190.10 186 264 9.1E-8 T 09-03-2017 ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.4E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 Gene3D G3DSA:1.10.10.10 3 86 8.9E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 Pfam PF03466 LysR substrate binding domain 90 298 1.2E-24 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 SUPERFAMILY SSF46785 2 112 2.73E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19065 9ef04c8f1dd7c66bd8bc089ec586b239 307 Gene3D G3DSA:3.40.190.10 90 185 1.5E-16 T 09-03-2017 ARZXY2_RS13130 a8261edf7a3b92c8483b211e99d65c4e 229 Gene3D G3DSA:1.10.287.1080 10 80 3.9E-7 T 09-03-2017 ARZXY2_RS13130 a8261edf7a3b92c8483b211e99d65c4e 229 SUPERFAMILY SSF101386 13 109 1.18E-19 T 09-03-2017 ARZXY2_RS13130 a8261edf7a3b92c8483b211e99d65c4e 229 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 35 108 3.1E-24 T 09-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core ARZXY2_RS03695 c011b647bc2ad6b56822b1545741a794 483 Pfam PF00437 Type II/IV secretion system protein 126 402 1.6E-88 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 ARZXY2_RS03695 c011b647bc2ad6b56822b1545741a794 483 Gene3D G3DSA:3.40.50.300 224 433 3.6E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03695 c011b647bc2ad6b56822b1545741a794 483 SUPERFAMILY SSF52540 106 419 7.79E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03695 c011b647bc2ad6b56822b1545741a794 483 Gene3D G3DSA:3.30.450.90 123 220 7.1E-38 T 09-03-2017 ARZXY2_RS02500 ed6660c7b150a7617c3d4124712a5362 325 Gene3D G3DSA:3.40.109.10 139 293 1.3E-29 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ARZXY2_RS02500 ed6660c7b150a7617c3d4124712a5362 325 Pfam PF00881 Nitroreductase family 148 205 1.6E-7 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 ARZXY2_RS02500 ed6660c7b150a7617c3d4124712a5362 325 Pfam PF00881 Nitroreductase family 218 291 1.6E-10 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 ARZXY2_RS02500 ed6660c7b150a7617c3d4124712a5362 325 SUPERFAMILY SSF55469 140 314 3.66E-31 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 Gene3D G3DSA:3.90.20.20 71 152 6.7E-20 T 09-03-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 Hamap MF_01151 Protein GrpE [grpE]. 6 211 16.213 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 PRINTS PR00773 GrpE protein signature 87 103 1.9E-21 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 PRINTS PR00773 GrpE protein signature 190 209 1.9E-21 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 PRINTS PR00773 GrpE protein signature 115 130 1.9E-21 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 PRINTS PR00773 GrpE protein signature 163 178 1.9E-21 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 Pfam PF01025 GrpE 73 210 3.8E-33 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 SUPERFAMILY SSF51064 156 210 4.18E-15 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 Gene3D G3DSA:2.30.22.10 155 210 3.1E-20 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 SUPERFAMILY SSF58014 73 152 3.79E-18 T 09-03-2017 ARZXY2_RS00725 ea80dab3387c1a143ec11721c168b4c5 213 ProSitePatterns PS01071 grpE protein signature. 166 209 - T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 ARZXY2_RS15955 55df6ed87470bde4902b633d3966699c 469 Gene3D G3DSA:3.40.190.10 179 379 2.2E-27 T 09-03-2017 ARZXY2_RS15955 55df6ed87470bde4902b633d3966699c 469 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 25 466 5.6E-192 T 09-03-2017 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding ARZXY2_RS15955 55df6ed87470bde4902b633d3966699c 469 Pfam PF01547 Bacterial extracellular solute-binding protein 77 373 8.9E-28 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS15955 55df6ed87470bde4902b633d3966699c 469 SUPERFAMILY SSF53850 57 420 6.29E-40 T 09-03-2017 ARZXY2_RS19145 c0f31791c967662b92484ed82c0eeb1f 280 Gene3D G3DSA:3.90.850.10 60 278 2.6E-71 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS19145 c0f31791c967662b92484ed82c0eeb1f 280 SUPERFAMILY SSF56529 63 279 2.35E-70 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS19145 c0f31791c967662b92484ed82c0eeb1f 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 278 2.9E-58 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Gene3D G3DSA:3.30.300.20 255 320 2.8E-31 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Pfam PF08529 NusA N-terminal domain 6 60 6.1E-7 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Pfam PF08529 NusA N-terminal domain 62 100 1.2E-5 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 75 319 8.8E-97 T 09-03-2017 IPR010213 Transcription termination factor NusA GO:0003723 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Gene3D G3DSA:2.40.50.140 106 175 1.1E-22 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 SUPERFAMILY SSF54814 256 319 2.75E-17 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Gene3D G3DSA:3.30.300.20 176 254 2.0E-32 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 325 25.317 T 09-03-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 SMART SM00316 110 175 0.0041 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Pfam PF13184 NusA-like KH domain 207 275 1.6E-27 T 09-03-2017 IPR025249 KH domain, NusA-like GO:0003723 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 SUPERFAMILY SSF50249 108 176 4.71E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 Gene3D G3DSA:3.30.1480.10 2 99 2.4E-28 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 SUPERFAMILY SSF54814 177 255 5.23E-27 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 ARZXY2_RS11560 b7a05a9245452042781a18b2de455788 326 SUPERFAMILY SSF69705 2 99 2.75E-27 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 Pfam PF00912 Transglycosylase 77 264 2.0E-57 T 09-03-2017 IPR001264 Glycosyl transferase, family 51 ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 SUPERFAMILY SSF56601 246 268 9.66E-72 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 SUPERFAMILY SSF56601 301 719 9.66E-72 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 SUPERFAMILY SSF53955 66 288 9.84E-69 T 09-03-2017 IPR023346 Lysozyme-like domain ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 Pfam PF00905 Penicillin binding protein transpeptidase domain 486 653 9.2E-14 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 Pfam PF00905 Penicillin binding protein transpeptidase domain 367 444 6.7E-5 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 Gene3D G3DSA:3.40.710.10 268 711 2.9E-84 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01530 7b97aadc24fc2880be2d6718f358fb71 729 Gene3D G3DSA:1.10.3810.10 77 267 1.1E-67 T 09-03-2017 ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 Pfam PF02687 FtsX-like permease family 548 661 2.2E-11 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 SMART SM00382 42 231 8.2E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 SUPERFAMILY SSF52540 13 229 1.33E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 Gene3D G3DSA:3.40.50.300 12 230 2.5E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 Pfam PF12704 MacB-like periplasmic core domain 292 480 1.6E-6 T 09-03-2017 IPR025857 MacB-like periplasmic core domain ARZXY2_RS14365 74009e90eed5811ab7982e0ef1ac511f 667 Pfam PF00005 ABC transporter 35 181 1.7E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 SMART SM01091 337 417 1.3E-21 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 SUPERFAMILY SSF54631 194 340 4.03E-32 T 09-03-2017 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Pfam PF01595 Domain of unknown function DUF21 11 184 1.4E-16 T 09-03-2017 IPR002550 Domain of unknown function DUF21 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Gene3D G3DSA:3.10.580.10 186 328 2.5E-19 T 09-03-2017 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 SMART SM00116 274 322 6.6 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 SMART SM00116 208 257 5.5E-8 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 SUPERFAMILY SSF56176 336 405 4.91E-17 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Pfam PF03471 Transporter associated domain 339 411 2.7E-16 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Gene3D G3DSA:3.30.465.10 329 407 1.4E-24 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Pfam PF00571 CBS domain 200 257 5.0E-10 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS08310 d9827ae3c400543ebe8e97412e3df2d7 443 Pfam PF00571 CBS domain 271 322 3.6E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS01035 f71697068996e1d3c3e3ca15653517e3 198 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 194 1.7E-42 T 09-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 ARZXY2_RS01035 f71697068996e1d3c3e3ca15653517e3 198 Gene3D G3DSA:3.20.20.70 1 197 2.2E-52 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS01035 f71697068996e1d3c3e3ca15653517e3 198 SUPERFAMILY SSF51366 1 196 1.05E-46 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS01035 f71697068996e1d3c3e3ca15653517e3 198 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 198 31.277 T 09-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 Pfam PF00069 Protein kinase domain 15 257 3.5E-48 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 Gene3D G3DSA:1.10.510.10 80 264 9.0E-50 T 09-03-2017 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 SMART SM00220 13 269 1.5E-58 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 Gene3D G3DSA:3.30.200.20 7 79 3.6E-20 T 09-03-2017 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 Pfam PF03793 PASTA domain 530 590 3.6E-6 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 Pfam PF03793 PASTA domain 466 522 6.0E-8 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 SUPERFAMILY SSF56112 374 454 6.34E-78 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 SUPERFAMILY SSF56112 10 270 6.34E-78 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 SMART SM00740 456 522 1.9E-4 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18440 bec1b7814fc733a5d775c960956f8151 615 SMART SM00740 526 595 0.11 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 Gene3D G3DSA:3.30.420.40 2 172 5.5E-32 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 PRINTS PR01217 Proline rich extensin signature 587 603 3.4E-11 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 PRINTS PR01217 Proline rich extensin signature 606 623 3.4E-11 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 PRINTS PR01217 Proline rich extensin signature 554 575 3.4E-11 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 PRINTS PR01217 Proline rich extensin signature 624 649 3.4E-11 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 Gene3D G3DSA:3.90.640.10 210 290 1.8E-10 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 Gene3D G3DSA:3.30.420.40 173 209 1.4E-14 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 Gene3D G3DSA:3.30.420.40 296 331 1.4E-14 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 Pfam PF00012 Hsp70 protein 89 355 1.0E-42 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 314 328 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 SUPERFAMILY SSF53067 169 354 1.06E-35 T 09-03-2017 ARZXY2_RS02170 3168e4cdb10f038596769e52cc0b2da0 679 SUPERFAMILY SSF53067 3 162 1.01E-31 T 09-03-2017 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 SUPERFAMILY SSF56112 17 326 6.79E-70 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 Gene3D G3DSA:3.30.200.20 16 101 1.1E-23 T 09-03-2017 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 30 53 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 Gene3D G3DSA:1.10.510.10 102 279 7.3E-42 T 09-03-2017 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 SMART SM00220 24 281 4.6E-58 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS19800 fd0b403d0ca6410534fc929075a373af 485 Pfam PF00069 Protein kinase domain 24 276 2.2E-46 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS03635 512d645853e0ee901e7c0c962df27072 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 307 2.8E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03635 512d645853e0ee901e7c0c962df27072 314 SUPERFAMILY SSF161098 48 313 4.58E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03635 512d645853e0ee901e7c0c962df27072 314 Gene3D G3DSA:1.10.3720.10 49 301 6.2E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09125 8c91c9cadf69343af5ac081d29268858 257 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 256 43.48 T 09-03-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ARZXY2_RS09125 8c91c9cadf69343af5ac081d29268858 257 Pfam PF13649 Methyltransferase domain 34 124 3.6E-17 T 09-03-2017 ARZXY2_RS09125 8c91c9cadf69343af5ac081d29268858 257 Gene3D G3DSA:1.10.150.290 182 237 3.3E-28 T 09-03-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ARZXY2_RS09125 8c91c9cadf69343af5ac081d29268858 257 Gene3D G3DSA:3.40.50.150 3 180 3.2E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS09125 8c91c9cadf69343af5ac081d29268858 257 SUPERFAMILY SSF53335 16 221 1.35E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 Pfam PF04321 RmlD substrate binding domain 189 463 2.0E-67 T 09-03-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 9 182 1.0E-76 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 12 180 2.4E-37 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 Gene3D G3DSA:2.60.120.10 7 183 1.7E-49 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 SUPERFAMILY SSF51182 9 183 7.51E-50 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 SUPERFAMILY SSF51735 189 466 1.54E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08715 61b640e3dcafcdfd408145f65a4e43f4 487 Gene3D G3DSA:3.40.50.720 189 413 2.3E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SMART SM00490 467 553 1.7E-16 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:3.40.50.300 15 98 5.3E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:3.40.50.300 286 346 5.3E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:3.40.50.300 396 417 5.3E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Pfam PF12344 Ultra-violet resistance protein B 559 600 6.4E-22 T 09-03-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SMART SM00487 18 433 2.9E-24 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SUPERFAMILY SSF52540 13 422 2.01E-132 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:4.10.860.10 651 690 2.0E-12 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Pfam PF02151 UvrB/uvrC motif 656 688 8.2E-8 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SUPERFAMILY SSF52540 477 599 4.33E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SUPERFAMILY SSF52540 41 89 4.33E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:3.30.2060.10 168 238 4.9E-12 T 09-03-2017 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Pfam PF04851 Type III restriction enzyme, res subunit 22 147 5.6E-10 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 689 42.275 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 SUPERFAMILY SSF46600 649 692 1.7E-9 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Pfam PF00271 Helicase conserved C-terminal domain 440 552 3.3E-17 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 Gene3D G3DSA:3.40.50.300 426 588 3.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09160 289eb98f961faf02e2447dfdb1ebd14e 699 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 687 0.0 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 SMART SM00450 26 140 2.1E-18 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 SMART SM00450 162 290 1.1E-20 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 Gene3D G3DSA:3.40.250.10 14 154 2.1E-36 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 Gene3D G3DSA:3.40.250.10 170 295 3.7E-33 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 SUPERFAMILY SSF52821 14 157 9.82E-37 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 ProSitePatterns PS00380 Rhodanese signature 1. 52 63 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 ProSitePatterns PS00683 Rhodanese C-terminal signature. 274 284 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 SUPERFAMILY SSF52821 168 295 1.14E-31 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 Pfam PF00581 Rhodanese-like domain 22 136 1.9E-14 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10430 1442124bfca4999f0e3b644143d8bc49 308 Pfam PF00581 Rhodanese-like domain 169 286 2.6E-18 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 Pfam PF00083 Sugar (and other) transporter 20 471 1.9E-111 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 14 466 7.1E-107 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 Gene3D G3DSA:1.20.1250.20 264 466 2.8E-24 T 09-03-2017 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 Gene3D G3DSA:1.20.1250.20 23 217 1.6E-27 T 09-03-2017 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 SUPERFAMILY SSF103473 8 468 4.32E-70 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 ProSitePatterns PS00216 Sugar transport proteins signature 1. 321 338 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 PRINTS PR00171 Sugar transporter signature 110 129 8.5E-25 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 PRINTS PR00171 Sugar transporter signature 277 287 8.5E-25 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 PRINTS PR00171 Sugar transporter signature 373 394 8.5E-25 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 PRINTS PR00171 Sugar transporter signature 396 408 8.5E-25 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS20260 ab458a52d8f548c2748d95798288f9b2 488 PRINTS PR00171 Sugar transporter signature 27 37 8.5E-25 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 SUPERFAMILY SSF51011 598 704 2.66E-20 T 09-03-2017 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Pfam PF00128 Alpha amylase, catalytic domain 198 281 3.5E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Pfam PF00128 Alpha amylase, catalytic domain 295 537 2.8E-6 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Gene3D G3DSA:2.60.40.10 12 158 1.4E-53 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Gene3D G3DSA:3.20.20.80 159 581 1.9E-115 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Gene3D G3DSA:2.60.40.1180 597 704 3.9E-22 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 17 103 8.9E-17 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 SUPERFAMILY SSF51445 507 580 2.94E-128 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 SUPERFAMILY SSF51445 143 478 2.94E-128 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 SUPERFAMILY SSF81296 12 154 6.72E-44 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 SMART SM00642 188 573 3.4E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS06050 e3354e5e1137f85c43e10a2e830eca41 720 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 13 704 1.2E-293 T 09-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SUPERFAMILY SSF52210 328 486 1.57E-31 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Pfam PF13380 CoA binding domain 206 330 1.2E-18 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SUPERFAMILY SSF55729 24 167 4.46E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SUPERFAMILY SSF51735 194 333 1.31E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Pfam PF13549 ATP-grasp domain 667 878 9.2E-52 T 09-03-2017 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 349 484 1.9E-41 T 09-03-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SUPERFAMILY SSF56059 673 880 4.91E-26 T 09-03-2017 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Gene3D G3DSA:3.40.50.720 186 325 1.2E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Gene3D G3DSA:3.40.50.261 326 483 3.8E-25 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Gene3D G3DSA:3.40.630.30 19 171 2.6E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Gene3D G3DSA:3.30.470.20 677 717 1.7E-4 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SUPERFAMILY SSF52210 491 635 1.44E-12 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 SMART SM00881 201 296 9.0E-30 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS10590 b947079829418a8537b361b4e79fca75 895 Pfam PF00583 Acetyltransferase (GNAT) family 85 159 2.3E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 Pfam PF00571 CBS domain 4 55 1.2E-11 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 Pfam PF00571 CBS domain 77 121 9.0E-10 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 SMART SM00116 11 59 1.3E-6 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 SMART SM00116 77 124 7.8E-7 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 SUPERFAMILY SSF54631 3 125 4.55E-31 T 09-03-2017 ARZXY2_RS13770 c6aa6edd54fe5fee750b74bdf2e5f454 143 Gene3D G3DSA:3.10.580.10 4 125 4.9E-31 T 09-03-2017 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 60 4.1E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 SUPERFAMILY SSF47413 16 73 3.26E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 Pfam PF13377 Periplasmic binding protein-like domain 181 345 1.3E-31 T 09-03-2017 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 SMART SM00354 15 85 1.5E-22 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 SUPERFAMILY SSF53822 74 348 8.7E-64 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 Gene3D G3DSA:3.40.50.2300 186 325 6.7E-42 T 09-03-2017 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 09-03-2017 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 Gene3D G3DSA:3.40.50.2300 68 185 7.5E-34 T 09-03-2017 ARZXY2_RS16570 26cd86168aaa4eea9bcba10009f2d908 350 Gene3D G3DSA:1.10.260.40 16 67 3.5E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Gene3D G3DSA:1.20.140.10 227 385 2.9E-61 T 09-03-2017 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 SUPERFAMILY SSF47203 235 385 2.58E-46 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 PIRSF PIRSF016578 3 386 2.0E-15 T 09-03-2017 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Gene3D G3DSA:1.10.540.10 4 119 1.2E-42 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 SUPERFAMILY SSF56645 4 250 1.44E-72 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 5.4E-44 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 225 5.4E-18 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 2.4E-36 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS11695 79192266435bf0f8ec721d3e458af40f 387 Gene3D G3DSA:2.40.110.10 123 226 9.2E-31 T 09-03-2017 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 09-03-2017 IPR019844 Cold-shock conserved site ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 SUPERFAMILY SSF50249 1 66 6.21E-26 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 PIRSF PIRSF002599 1 67 3.4E-27 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.4E-32 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 PRINTS PR00050 Cold shock protein signature 25 34 2.4E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 PRINTS PR00050 Cold shock protein signature 40 58 2.4E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 PRINTS PR00050 Cold shock protein signature 4 19 2.4E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 Gene3D G3DSA:2.40.50.140 1 65 4.4E-33 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS13485 e7737ce98750785e1b0535569ac44ce8 67 SMART SM00357 3 67 2.3E-30 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 25 933 0.0 T 09-03-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Gene3D G3DSA:3.30.499.10 29 245 1.0E-78 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Pfam PF00330 Aconitase family (aconitate hydratase) 65 600 5.6E-178 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 289 302 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 166 174 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 142 155 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 213 228 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 199 212 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 275 288 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 368 382 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 469 480 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 PRINTS PR00415 Aconitase family signature 531 544 4.6E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Gene3D G3DSA:3.20.19.10 675 933 1.4E-78 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 ProSitePatterns PS00450 Aconitase family signature 1. 465 481 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Gene3D G3DSA:3.30.499.10 364 389 1.0E-67 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Gene3D G3DSA:3.30.499.10 457 613 1.0E-67 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 SUPERFAMILY SSF52016 669 932 4.32E-84 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 SUPERFAMILY SSF53732 7 402 1.7E-220 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 SUPERFAMILY SSF53732 439 665 1.7E-220 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Pfam PF00694 Aconitase C-terminal domain 730 859 3.3E-45 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 Gene3D G3DSA:3.40.1060.10 246 363 6.9E-34 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS10515 cf52766f172b302722929289828d50b7 935 ProSitePatterns PS01244 Aconitase family signature 2. 531 544 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 SUPERFAMILY SSF52794 405 491 8.89E-23 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 SUPERFAMILY SSF55804 552 685 4.97E-34 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 17 366 3.4E-153 T 09-03-2017 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 407 491 2.4E-10 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 Pfam PF02378 Phosphotransferase system, EIIC 26 296 2.4E-14 T 09-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 593 609 - T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 Gene3D G3DSA:3.40.930.10 550 685 1.2E-36 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 552 684 2.4E-29 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS20210 82fb1ab35ab7f360f2d320d7ac7ae7f0 689 Gene3D G3DSA:3.40.50.10370 405 496 1.7E-37 T 09-03-2017 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 ARZXY2_RS16240 bcd2b3e35e2827185824b7826c271970 293 SMART SM00382 43 234 3.4E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS16240 bcd2b3e35e2827185824b7826c271970 293 Gene3D G3DSA:3.40.50.300 10 257 4.3E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16240 bcd2b3e35e2827185824b7826c271970 293 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS16240 bcd2b3e35e2827185824b7826c271970 293 SUPERFAMILY SSF52540 11 256 2.77E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16240 bcd2b3e35e2827185824b7826c271970 293 Pfam PF00005 ABC transporter 34 184 1.4E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 SUPERFAMILY SSF56327 164 457 3.18E-46 T 09-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.2E-34 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 438 2.8E-37 T 09-03-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 Gene3D G3DSA:3.90.110.10 164 452 8.0E-79 T 09-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 Pfam PF02056 Family 4 glycosyl hydrolase 6 176 1.2E-36 T 09-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 09-03-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 SUPERFAMILY SSF51735 1 163 7.51E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03810 632ce00bf889b3485184e852a5a8c044 465 Gene3D G3DSA:3.40.50.720 1 163 2.5E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02525 ae675f197e5057243d269a5424c2f577 151 Pfam PF00534 Glycosyl transferases group 1 4 116 1.4E-21 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS02525 ae675f197e5057243d269a5424c2f577 151 SUPERFAMILY SSF53756 3 116 1.05E-28 T 09-03-2017 ARZXY2_RS02525 ae675f197e5057243d269a5424c2f577 151 Gene3D G3DSA:3.40.50.2000 6 117 1.5E-15 T 09-03-2017 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 Gene3D G3DSA:3.50.50.60 19 111 2.9E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 Gene3D G3DSA:3.50.50.60 170 287 6.0E-14 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 Gene3D G3DSA:3.50.50.60 112 150 1.9E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 203 262 5.2E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 21 164 3.8E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 SUPERFAMILY SSF51905 15 290 7.35E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 22 41 4.7E-14 T 09-03-2017 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 4.7E-14 T 09-03-2017 ARZXY2_RS12665 170a45dd7e03b7e960d90707443da52c 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 4.7E-14 T 09-03-2017 ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 PIRSF PIRSF001227 3 711 9.2E-179 T 09-03-2017 IPR014395 Penicillin acylase GO:0016811 ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 Gene3D G3DSA:1.10.439.10 16 166 7.1E-37 T 09-03-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 SUPERFAMILY SSF56235 16 708 1.31E-141 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 Gene3D G3DSA:3.60.20.10 181 257 1.8E-69 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 Gene3D G3DSA:3.60.20.10 340 533 1.8E-69 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 Pfam PF01804 Penicillin amidase 16 706 1.2E-166 T 09-03-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 ARZXY2_RS00420 bac3fd0652828eb5ebd6fe64e2e2e889 711 Gene3D G3DSA:2.30.120.10 258 327 5.3E-9 T 09-03-2017 ARZXY2_RS04730 3d214ee33bec1f1de1709e5bf9d580c2 315 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 2.1E-63 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 ARZXY2_RS04730 3d214ee33bec1f1de1709e5bf9d580c2 315 SUPERFAMILY SSF52540 5 290 6.34E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04730 3d214ee33bec1f1de1709e5bf9d580c2 315 Gene3D G3DSA:3.40.50.300 19 183 7.4E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04730 3d214ee33bec1f1de1709e5bf9d580c2 315 PIRSF PIRSF002849 1 315 2.6E-127 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted ARZXY2_RS04730 3d214ee33bec1f1de1709e5bf9d580c2 315 Gene3D G3DSA:1.10.8.300 205 311 3.4E-36 T 09-03-2017 ARZXY2_RS01550 616cead5d788e01d6ebab854cde5cc63 98 SUPERFAMILY SSF81442 31 96 8.5E-5 T 09-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 SUPERFAMILY SSF53067 1 179 1.81E-56 T 09-03-2017 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PIRSF PIRSF000722 1 383 3.2E-120 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 304 320 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 187 208 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 282 295 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 157 170 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 3 14 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 PRINTS PR00471 Acetate kinase family signature 361 373 2.7E-37 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 Hamap MF_00020 Acetate kinase [ackA]. 1 383 155.667 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 TIGRFAM TIGR00016 ackA: acetate kinase 1 378 5.4E-115 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 SUPERFAMILY SSF53067 141 380 8.64E-78 T 09-03-2017 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 Gene3D G3DSA:3.30.420.40 1 190 1.6E-11 T 09-03-2017 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 Gene3D G3DSA:3.30.420.40 191 379 2.4E-70 T 09-03-2017 ARZXY2_RS06045 03f2accab11c721c5a62775c6fd608c4 383 Pfam PF00871 Acetokinase family 3 374 1.6E-113 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 SUPERFAMILY SSF46689 7 76 2.23E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 Pfam PF13977 Bacterial transcriptional repressor 118 188 3.5E-6 T 09-03-2017 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 SUPERFAMILY SSF48498 88 191 1.78E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.8E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 Gene3D G3DSA:1.10.357.10 12 191 2.3E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15820 a34dbcae57925c850e3988ee0885b0a1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS13935 72783b7910d509820946d9bd3650459e 402 Pfam PF10117 McrBC 5-methylcytosine restriction system component 43 344 2.1E-58 T 09-03-2017 IPR019292 5-methylcytosine restriction system component ARZXY2_RS01410 3038ef26afd79dbf6a8d7c7406a6185a 161 Gene3D G3DSA:3.30.530.20 3 123 4.6E-8 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS01410 3038ef26afd79dbf6a8d7c7406a6185a 161 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 106 4.4E-11 T 09-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain ARZXY2_RS01410 3038ef26afd79dbf6a8d7c7406a6185a 161 SUPERFAMILY SSF55961 1 140 2.65E-23 T 09-03-2017 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 SUPERFAMILY SSF50129 4 186 2.13E-51 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 4.0E-208 T 09-03-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 Pfam PF00107 Zinc-binding dehydrogenase 190 316 4.9E-30 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 Gene3D G3DSA:3.40.50.720 183 302 4.0E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 SUPERFAMILY SSF50129 310 359 4.08E-9 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 7.7E-26 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 SMART SM00829 14 355 6.1E-5 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 SUPERFAMILY SSF51735 153 326 1.6E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07880 26755b8b18061792eac2d129f94a0884 361 Gene3D G3DSA:3.90.180.10 3 182 3.9E-55 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS13365 7b342a1f1110f052d1da96b704c22919 361 SUPERFAMILY SSF51230 68 128 2.04E-6 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS13365 7b342a1f1110f052d1da96b704c22919 361 Gene3D G3DSA:2.40.50.100 68 159 7.9E-9 T 09-03-2017 ARZXY2_RS02975 1c6f32eadbaa2093b1dd13bd5ac6251e 138 Pfam PF05610 Protein of unknown function (DUF779) 27 127 2.5E-46 T 09-03-2017 IPR008497 Protein of unknown function DUF779 ARZXY2_RS02975 1c6f32eadbaa2093b1dd13bd5ac6251e 138 PIRSF PIRSF009151 4 137 8.1E-54 T 09-03-2017 IPR008497 Protein of unknown function DUF779 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 Gene3D G3DSA:3.40.630.30 173 317 9.2E-33 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 SUPERFAMILY SSF55729 45 154 7.09E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 17 317 2.7E-108 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 12 319 34.907 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 Gene3D G3DSA:3.40.630.30 77 146 2.3E-10 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 Pfam PF00583 Acetyltransferase (GNAT) family 87 146 4.5E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 Pfam PF00583 Acetyltransferase (GNAT) family 229 308 1.9E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 PIRSF PIRSF021524 5 323 3.0E-123 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 ARZXY2_RS03310 63aeb49f192e11d74c137611a1147a23 323 SUPERFAMILY SSF55729 128 317 5.23E-34 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 3.6E-15 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 Gene3D G3DSA:1.10.10.10 162 219 1.3E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 Gene3D G3DSA:3.40.50.2300 17 161 9.8E-33 T 09-03-2017 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 SUPERFAMILY SSF52172 17 192 1.08E-27 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 Pfam PF00072 Response regulator receiver domain 19 129 1.9E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 5.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 5.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 5.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 SMART SM00421 161 218 1.3E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09855 3d6a5aea81be30943ab9f25a11aacb74 231 SMART SM00448 17 129 8.4E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 Gene3D G3DSA:3.30.420.40 228 359 2.0E-39 T 09-03-2017 ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 Gene3D G3DSA:3.30.420.40 90 227 1.2E-28 T 09-03-2017 ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 SUPERFAMILY SSF46785 15 79 4.47E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 SUPERFAMILY SSF53067 90 386 1.03E-39 T 09-03-2017 ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 Pfam PF00480 ROK family 91 382 3.3E-42 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 Gene3D G3DSA:1.10.10.10 14 86 6.7E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00255 1b137c20d57fe21775cfadd091ebcb29 403 Pfam PF12802 MarR family 23 67 1.4E-6 T 09-03-2017 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 53 1.5E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 SUPERFAMILY SSF53822 66 346 6.56E-64 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 Pfam PF13377 Periplasmic binding protein-like domain 175 344 1.2E-39 T 09-03-2017 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 Gene3D G3DSA:3.40.50.2300 59 180 2.0E-31 T 09-03-2017 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 Gene3D G3DSA:3.40.50.2300 181 321 4.7E-48 T 09-03-2017 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 Gene3D G3DSA:1.10.260.40 6 58 3.6E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 SMART SM00354 4 76 1.1E-19 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS02760 01d1659a57d5bc839fec0084024294a6 349 SUPERFAMILY SSF47413 3 64 1.82E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 1.1E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 SUPERFAMILY SSF53822 72 336 3.08E-56 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 SUPERFAMILY SSF47413 11 69 1.59E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 Pfam PF13377 Periplasmic binding protein-like domain 175 333 7.4E-32 T 09-03-2017 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 Gene3D G3DSA:3.40.50.2300 62 180 1.6E-36 T 09-03-2017 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 Gene3D G3DSA:3.40.50.2300 181 310 2.4E-40 T 09-03-2017 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 Gene3D G3DSA:1.10.260.40 11 61 7.9E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16270 73eb79ae990440084853a37c9b60bf32 338 SMART SM00354 11 81 1.6E-26 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF81653 94 188 1.57E-22 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Gene3D G3DSA:2.70.150.10 2 37 2.0E-24 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Gene3D G3DSA:2.70.150.10 89 189 2.0E-24 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF81665 2 94 5.49E-54 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF81665 592 780 5.49E-54 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF81665 192 294 5.49E-54 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Gene3D G3DSA:1.20.1110.10 512 710 1.4E-44 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Gene3D G3DSA:1.20.1110.10 45 88 1.4E-44 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 403 421 2.4E-7 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 543 559 2.4E-7 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 557 1.2E-20 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 302 308 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Pfam PF00122 E1-E2 ATPase 65 291 7.9E-53 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF56784 442 585 5.22E-33 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 SUPERFAMILY SSF56784 288 359 5.22E-33 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 578 9.1E-25 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 562 9.1E-25 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 141 155 9.1E-25 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 476 9.1E-25 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 300 314 9.1E-25 T 09-03-2017 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 514 623 5.1E-23 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 68 490 1.5E-32 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09935 b58d113bba01905aff7513f5b44ad05f 804 Gene3D G3DSA:3.40.1110.10 290 321 3.4E-6 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS10785 811cddb62de17080d3ac80ee52bd10fb 152 Pfam PF01613 Flavin reductase like domain 2 143 2.2E-29 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS10785 811cddb62de17080d3ac80ee52bd10fb 152 Gene3D G3DSA:2.30.110.10 2 143 1.4E-42 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10785 811cddb62de17080d3ac80ee52bd10fb 152 SUPERFAMILY SSF50475 2 145 2.5E-36 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10785 811cddb62de17080d3ac80ee52bd10fb 152 SMART SM00903 2 144 2.2E-43 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS16830 f48d15b5cfe0b8b7d03ff67cf0b3b4cc 223 Pfam PF01596 O-methyltransferase 35 207 1.5E-43 T 09-03-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 ARZXY2_RS16830 f48d15b5cfe0b8b7d03ff67cf0b3b4cc 223 Gene3D G3DSA:3.40.50.150 10 221 4.0E-62 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS16830 f48d15b5cfe0b8b7d03ff67cf0b3b4cc 223 SUPERFAMILY SSF53335 17 221 1.41E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.30.70.380 756 847 2.1E-28 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SMART SM00873 241 414 7.8E-87 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Pfam PF01588 Putative tRNA binding domain 48 156 1.2E-5 T 09-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SMART SM00874 430 498 4.7E-22 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Pfam PF03484 tRNA synthetase B5 domain 432 498 6.4E-17 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF56037 241 423 9.68E-68 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Pfam PF03147 Ferredoxin-fold anticodon binding domain 754 847 4.1E-23 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF54991 750 847 5.49E-26 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF50249 42 212 4.51E-23 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Pfam PF03483 B3/4 domain 241 414 1.3E-68 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 847 8.6E-183 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SMART SM00896 754 847 1.6E-39 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF46955 431 502 1.19E-17 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.30.56.20 431 502 4.7E-23 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF55681 640 741 2.48E-41 T 09-03-2017 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 SUPERFAMILY SSF55681 494 610 2.48E-41 T 09-03-2017 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.30.930.10 514 742 5.6E-61 T 09-03-2017 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 841 39.828 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.30.56.10 3 40 5.8E-12 T 09-03-2017 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.30.56.10 177 206 5.8E-12 T 09-03-2017 ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:2.40.50.140 45 175 2.0E-36 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11245 2578285ae61e1040282ec7fc012c6d6b 847 Gene3D G3DSA:3.50.40.10 239 420 8.6E-80 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 ARZXY2_RS03500 42dfe9147c6a683828a89a9bdcd8aa59 205 SUPERFAMILY SSF52166 6 194 9.16E-69 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03500 42dfe9147c6a683828a89a9bdcd8aa59 205 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 3 198 31.796 T 09-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03500 42dfe9147c6a683828a89a9bdcd8aa59 205 Pfam PF00573 Ribosomal protein L4/L1 family 7 193 2.0E-61 T 09-03-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03500 42dfe9147c6a683828a89a9bdcd8aa59 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 7 192 2.4E-68 T 09-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03500 42dfe9147c6a683828a89a9bdcd8aa59 205 Gene3D G3DSA:3.40.1370.10 48 193 2.1E-48 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS07195 728ce2b4918d0efb77a82d0dcb2ec4d1 550 SUPERFAMILY SSF55781 2 144 2.01E-19 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS07195 728ce2b4918d0efb77a82d0dcb2ec4d1 550 Pfam PF13185 GAF domain 4 129 1.8E-12 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS07195 728ce2b4918d0efb77a82d0dcb2ec4d1 550 SMART SM00065 1 142 0.0027 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS07195 728ce2b4918d0efb77a82d0dcb2ec4d1 550 Pfam PF13556 PucR C-terminal helix-turn-helix domain 471 528 6.0E-15 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS07195 728ce2b4918d0efb77a82d0dcb2ec4d1 550 Gene3D G3DSA:3.30.450.40 1 146 6.3E-24 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Gene3D G3DSA:1.25.60.10 165 277 2.3E-37 T 09-03-2017 ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Pfam PF05239 PRC-barrel domain 8 75 7.8E-6 T 09-03-2017 IPR027275 PRC-barrel domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 SMART SM00924 179 282 5.9E-35 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Gene3D G3DSA:3.10.580.10 281 406 5.6E-23 T 09-03-2017 ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 SMART SM00116 358 406 2.7E-4 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 SUPERFAMILY SSF158791 167 279 2.35E-30 T 09-03-2017 ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Pfam PF03448 MgtE intracellular N domain 179 280 1.7E-26 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Pfam PF00571 CBS domain 357 406 4.4E-9 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 Pfam PF00571 CBS domain 283 345 0.0016 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 SUPERFAMILY SSF50346 12 69 9.26E-5 T 09-03-2017 IPR011033 PRC-barrel-like ARZXY2_RS04365 c667b6de20ca2450f8c7ecdacd3cdaaa 427 SUPERFAMILY SSF54631 281 422 7.47E-26 T 09-03-2017 ARZXY2_RS17435 6792479825ad0956cbd1f7e6a1eca112 291 Gene3D G3DSA:3.20.20.70 3 259 2.0E-68 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS17435 6792479825ad0956cbd1f7e6a1eca112 291 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 257 3.3E-62 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS17435 6792479825ad0956cbd1f7e6a1eca112 291 PIRSF PIRSF001359 1 271 1.5E-50 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 ARZXY2_RS17435 6792479825ad0956cbd1f7e6a1eca112 291 SUPERFAMILY SSF51569 6 253 6.78E-58 T 09-03-2017 ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 1.3E-25 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 3 47 7.3E-19 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 148 1.1E-37 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 SUPERFAMILY SSF55653 58 149 6.67E-22 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 SUPERFAMILY SSF55658 3 57 1.1E-16 T 09-03-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 149 24.127 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 Gene3D G3DSA:3.10.430.100 63 149 1.1E-26 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal ARZXY2_RS18795 f7b6e4256d3020a5576fd07f49026be6 150 Gene3D G3DSA:3.40.5.10 3 52 8.5E-21 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 Pfam PF00990 Diguanylate cyclase, GGDEF domain 138 295 4.6E-44 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 Pfam PF00072 Response regulator receiver domain 3 112 7.2E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 SUPERFAMILY SSF52172 1 137 5.83E-37 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 135 299 1.5E-47 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 SMART SM00267 127 299 6.5E-59 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 Gene3D G3DSA:3.30.70.270 139 301 9.0E-50 T 09-03-2017 ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 Gene3D G3DSA:3.40.50.2300 1 122 6.3E-34 T 09-03-2017 ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 SMART SM00448 1 114 5.1E-36 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02365 4bff79f1f957b721219f6ecf2eca4b60 306 SUPERFAMILY SSF55073 143 299 5.89E-43 T 09-03-2017 IPR029787 Nucleotide cyclase ARZXY2_RS04315 b0e7ea6b7746ce7806992e864868e674 275 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 87 259 2.3E-43 T 09-03-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG ARZXY2_RS04315 b0e7ea6b7746ce7806992e864868e674 275 Pfam PF03641 Possible lysine decarboxylase 129 258 1.9E-33 T 09-03-2017 IPR031100 LOG family ARZXY2_RS04315 b0e7ea6b7746ce7806992e864868e674 275 Gene3D G3DSA:3.40.50.450 66 260 2.3E-63 T 09-03-2017 ARZXY2_RS04315 b0e7ea6b7746ce7806992e864868e674 275 SUPERFAMILY SSF102405 58 258 9.31E-64 T 09-03-2017 ARZXY2_RS17520 5a34daf017f0e3ca6b27e0708430d0b7 323 Pfam PF00248 Aldo/keto reductase family 15 310 5.1E-72 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17520 5a34daf017f0e3ca6b27e0708430d0b7 323 SUPERFAMILY SSF51430 1 315 1.57E-96 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17520 5a34daf017f0e3ca6b27e0708430d0b7 323 Gene3D G3DSA:3.20.20.100 1 315 1.9E-97 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 Gene3D G3DSA:2.30.40.10 494 526 2.4E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 Gene3D G3DSA:3.20.20.140 199 493 1.5E-33 T 09-03-2017 ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 Gene3D G3DSA:2.30.40.10 3 86 5.9E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 SUPERFAMILY SSF51556 197 510 4.66E-33 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 SUPERFAMILY SSF51556 57 117 4.66E-33 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 Pfam PF07969 Amidohydrolase family 46 549 2.2E-79 T 09-03-2017 IPR013108 Amidohydrolase 3 ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 SUPERFAMILY SSF51338 510 549 4.7E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS15465 a83df7abf41ceb6d4a540b953a1498ef 574 SUPERFAMILY SSF51338 2 58 4.7E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS18600 f404864f6e6e0a13e1b7cc3574086b7a 270 Pfam PF13614 AAA domain 12 194 8.2E-55 T 09-03-2017 IPR025669 AAA domain ARZXY2_RS18600 f404864f6e6e0a13e1b7cc3574086b7a 270 Gene3D G3DSA:3.40.50.300 12 269 9.1E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18600 f404864f6e6e0a13e1b7cc3574086b7a 270 SUPERFAMILY SSF52540 11 269 1.25E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 SMART SM00354 10 85 6.8E-21 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 Gene3D G3DSA:1.10.260.40 11 67 1.1E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 SUPERFAMILY SSF53822 80 338 2.94E-35 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 Pfam PF13377 Periplasmic binding protein-like domain 181 336 3.2E-21 T 09-03-2017 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 62 1.5E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 SUPERFAMILY SSF47413 10 74 4.33E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 Gene3D G3DSA:3.40.50.2300 181 336 6.6E-29 T 09-03-2017 ARZXY2_RS12315 0b8bc1e6d6f411b721bf132b9bc466b5 347 Gene3D G3DSA:3.40.50.2300 68 180 7.9E-17 T 09-03-2017 ARZXY2_RS15645 552986b201b32d53cbbfe47af634fc5e 529 SUPERFAMILY SSF56524 229 424 2.22E-54 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS15645 552986b201b32d53cbbfe47af634fc5e 529 Pfam PF00174 Oxidoreductase molybdopterin binding domain 255 402 1.9E-38 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS15645 552986b201b32d53cbbfe47af634fc5e 529 SUPERFAMILY SSF81296 420 528 1.12E-22 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS15645 552986b201b32d53cbbfe47af634fc5e 529 Gene3D G3DSA:2.60.40.650 424 528 4.5E-19 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS15645 552986b201b32d53cbbfe47af634fc5e 529 Gene3D G3DSA:3.90.420.10 226 423 6.4E-52 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 164 3.5E-40 T 09-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 Pfam PF01782 RimM N-terminal domain 4 85 2.5E-22 T 09-03-2017 IPR002676 RimM protein GO:0006364 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 Gene3D G3DSA:2.30.30.240 95 164 5.1E-16 T 09-03-2017 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 164 22.441 T 09-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 Gene3D G3DSA:2.40.30.60 3 87 1.6E-19 T 09-03-2017 IPR002676 RimM protein GO:0006364 ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 SUPERFAMILY SSF50447 3 87 3.77E-18 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS07015 747ef5737d8dde6f6d98d859dd484a13 179 SUPERFAMILY SSF50346 95 164 5.89E-16 T 09-03-2017 IPR011033 PRC-barrel-like ARZXY2_RS09710 b77c653c20dca457f20d05521a78ff1e 485 PIRSF PIRSF006060 3 484 3.2E-52 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS09710 b77c653c20dca457f20d05521a78ff1e 485 Pfam PF13520 Amino acid permease 34 451 3.3E-25 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 Gene3D G3DSA:3.40.50.300 361 544 7.0E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 Gene3D G3DSA:3.40.50.300 8 104 3.3E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 Gene3D G3DSA:3.40.50.300 136 276 3.3E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 SUPERFAMILY SSF52540 5 247 8.58E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 SMART SM00382 29 232 5.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 SMART SM00382 374 541 3.3E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 Pfam PF00005 ABC transporter 367 495 1.6E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 Pfam PF00005 ABC transporter 21 187 4.8E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14160 4f75db97901b289566c4babbc7123934 553 SUPERFAMILY SSF52540 357 545 8.12E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 165 192 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 SUPERFAMILY SSF51735 125 303 4.32E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 40 328 2.2E-11 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 Gene3D G3DSA:3.40.50.720 140 306 2.0E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 SUPERFAMILY SSF52283 20 144 1.19E-23 T 09-03-2017 ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 Gene3D G3DSA:3.40.50.720 35 139 4.5E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18265 d006439d63cd0fe3085b0c2ef52e02b5 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 131 303 2.0E-58 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 Pfam PF01029 NusB family 66 188 2.8E-23 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 Gene3D G3DSA:1.10.940.10 65 221 1.4E-44 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 Pfam PF01189 16S rRNA methyltransferase RsmB/F 323 518 5.0E-52 T 09-03-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 328 338 4.0E-21 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 503 520 4.0E-21 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 306 4.0E-21 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 396 408 4.0E-21 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 446 462 4.0E-21 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 Gene3D G3DSA:3.40.50.150 304 521 6.2E-51 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 SUPERFAMILY SSF48013 66 220 8.34E-33 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 395 406 - T 09-03-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 ARZXY2_RS10350 e2369640b801fb987729d2ba9802a928 522 SUPERFAMILY SSF53335 284 521 4.56E-50 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 86 102 - T 09-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 SUPERFAMILY SSF55620 21 207 8.15E-76 T 09-03-2017 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 Gene3D G3DSA:3.30.1130.10 79 207 4.7E-58 T 09-03-2017 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 Pfam PF01227 GTP cyclohydrolase I 30 207 7.0E-76 T 09-03-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 136 146 - T 09-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 Gene3D G3DSA:1.10.286.10 25 76 9.9E-25 T 09-03-2017 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 207 5.4E-72 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 ARZXY2_RS17990 65956d4ff81171c5063c3d0eae3ef401 210 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 26 208 40.97 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 ARZXY2_RS09765 89756d73c4b9d78ee2ca0457e14f5004 425 Gene3D G3DSA:3.40.640.10 76 306 6.9E-61 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS09765 89756d73c4b9d78ee2ca0457e14f5004 425 SUPERFAMILY SSF53383 30 411 3.5E-83 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS09765 89756d73c4b9d78ee2ca0457e14f5004 425 Gene3D G3DSA:3.90.1150.10 307 414 4.2E-12 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS09765 89756d73c4b9d78ee2ca0457e14f5004 425 Pfam PF00202 Aminotransferase class-III 46 354 6.7E-51 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 Gene3D G3DSA:3.40.50.10300 187 409 7.9E-75 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 Pfam PF02441 Flavoprotein 2 127 2.1E-25 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 SUPERFAMILY SSF102645 187 407 5.1E-63 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 190 381 1.9E-64 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 Gene3D G3DSA:3.40.50.1950 2 172 1.9E-53 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 405 2.5E-108 T 09-03-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 ARZXY2_RS08165 56069bf67df32260a0ad7478ddb23f2a 417 SUPERFAMILY SSF52507 2 171 3.53E-51 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 ARZXY2_RS20060 83a47c2f15c2ba35a208b4a9d1a5ec7b 435 Gene3D G3DSA:3.40.640.10 85 305 9.6E-75 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS20060 83a47c2f15c2ba35a208b4a9d1a5ec7b 435 Gene3D G3DSA:3.90.1150.10 306 423 2.8E-10 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS20060 83a47c2f15c2ba35a208b4a9d1a5ec7b 435 SUPERFAMILY SSF53383 32 424 8.66E-105 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS20060 83a47c2f15c2ba35a208b4a9d1a5ec7b 435 Pfam PF00155 Aminotransferase class I and II 63 418 5.9E-39 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Gene3D G3DSA:3.30.310.50 389 471 3.5E-22 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Gene3D G3DSA:3.40.120.10 4 172 5.8E-31 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 393 470 5.9E-14 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 SUPERFAMILY SSF53738 292 383 2.35E-23 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 165 269 5.6E-24 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 SUPERFAMILY SSF55957 387 472 4.19E-19 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Gene3D G3DSA:3.40.120.10 183 265 5.9E-31 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 286 385 1.2E-21 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 SUPERFAMILY SSF53738 164 271 1.02E-28 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Gene3D G3DSA:3.40.120.10 266 388 3.3E-30 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 142 1.3E-31 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 181 200 4.2E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 249 264 4.2E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 220 233 4.2E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 4.2E-22 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS15085 2847e12246ece0b63bda79d09f5cdc41 472 SUPERFAMILY SSF53738 7 176 1.29E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS13660 a902cc9dd29c45cf3240fb1c4e2f51b3 254 Gene3D G3DSA:3.40.50.720 20 249 3.6E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13660 a902cc9dd29c45cf3240fb1c4e2f51b3 254 Pfam PF00106 short chain dehydrogenase 21 179 1.1E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13660 a902cc9dd29c45cf3240fb1c4e2f51b3 254 SUPERFAMILY SSF51735 21 249 3.46E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 Gene3D G3DSA:3.40.50.2300 183 312 3.0E-43 T 09-03-2017 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 Gene3D G3DSA:1.10.260.40 13 64 4.4E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 Gene3D G3DSA:3.40.50.2300 65 182 2.2E-29 T 09-03-2017 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 7.2E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 SUPERFAMILY SSF47413 11 70 2.91E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 Pfam PF13377 Periplasmic binding protein-like domain 176 333 1.4E-35 T 09-03-2017 ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 SUPERFAMILY SSF53822 71 335 9.01E-62 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS14620 378a8f3ccb03e17c533c36f9492014c1 339 SMART SM00354 12 82 8.3E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06430 307b464792584b6efac72b5f51c97a92 358 SUPERFAMILY SSF109604 130 297 2.9E-38 T 09-03-2017 ARZXY2_RS06430 307b464792584b6efac72b5f51c97a92 358 Gene3D G3DSA:1.10.3210.10 130 299 3.6E-44 T 09-03-2017 IPR006674 HD domain ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF55464 302 561 7.78E-75 T 09-03-2017 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF55464 131 209 7.78E-75 T 09-03-2017 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Pfam PF01443 Viral (Superfamily 1) RNA helicase 1042 1121 1.9E-4 T 09-03-2017 IPR027351 (+) RNA virus helicase core domain GO:0005524 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Pfam PF08275 DNA primase catalytic core, N-terminal domain 1728 1853 7.6E-20 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF52540 725 905 3.13E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Pfam PF08751 TrwC relaxase 139 545 4.8E-93 T 09-03-2017 IPR014862 TrwC relaxase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Pfam PF13155 Toprim-like 1864 1955 4.0E-7 T 09-03-2017 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Pfam PF13604 AAA domain 728 953 1.8E-54 T 09-03-2017 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Gene3D G3DSA:3.90.980.10 1706 1842 1.2E-21 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF56731 1706 1999 1.52E-56 T 09-03-2017 ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF52540 871 931 6.68E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SUPERFAMILY SSF52540 971 1129 6.68E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Gene3D G3DSA:3.40.50.300 1070 1124 1.5E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Gene3D G3DSA:3.40.50.300 874 998 1.5E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 SMART SM00493 1861 1940 0.0022 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Gene3D G3DSA:3.40.50.300 725 872 3.2E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19435 2a97c4165901400acb23e2899dd6deb3 2109 Gene3D G3DSA:3.40.1360.10 1843 1973 2.1E-22 T 09-03-2017 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 Gene3D G3DSA:3.30.110.10 64 156 2.6E-35 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 SUPERFAMILY SSF54364 1 63 2.09E-22 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 4.5E-55 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 Gene3D G3DSA:3.10.20.80 1 63 6.6E-27 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 4.9E-24 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 SUPERFAMILY SSF55200 68 156 1.02E-29 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 69 152 6.8E-32 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS11300 4e93beeb5a06d54215ed0c47d32a5870 327 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 24.55 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 Gene3D G3DSA:1.10.1040.10 202 296 7.3E-24 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 PIRSF PIRSF000105 11 327 2.5E-78 T 09-03-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 SUPERFAMILY SSF48179 200 295 2.3E-23 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 Gene3D G3DSA:3.40.50.720 10 201 2.2E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 197 221 - T 09-03-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 18 198 9.3E-50 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 296 7.7E-24 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS13805 ad79c619a0cb63ebe2864d5810f238ce 330 SUPERFAMILY SSF51735 16 198 5.99E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 55 171 2.9E-25 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 Pfam PF00107 Zinc-binding dehydrogenase 213 336 1.1E-24 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 Gene3D G3DSA:3.40.50.720 206 320 3.3E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 Gene3D G3DSA:3.90.180.10 32 205 1.3E-60 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 206 234 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 88 102 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 SMART SM00829 41 370 2.5E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 SUPERFAMILY SSF50129 37 198 1.4E-47 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS05105 3b5d7b198e4297e8a8cdd977adf29a6e 384 SUPERFAMILY SSF51735 176 340 5.97E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 ProSitePatterns PS00056 Ribosomal protein S17 signature. 72 84 - T 09-03-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 Pfam PF00366 Ribosomal protein S17 26 93 2.1E-30 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 21 92 7.1E-34 T 09-03-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 SUPERFAMILY SSF50249 21 98 2.91E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 PRINTS PR00973 Ribosomal protein S17 family signature 40 63 4.9E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 PRINTS PR00973 Ribosomal protein S17 family signature 72 82 4.9E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 PRINTS PR00973 Ribosomal protein S17 family signature 82 89 4.9E-12 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 26 92 4.0E-30 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 Gene3D G3DSA:2.40.50.140 21 98 7.8E-35 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03540 76b1b4eaacc20f5c16e061b0724feaa3 99 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 19 97 24.084 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Pfam PF00742 Homoserine dehydrogenase 138 321 4.9E-70 T 09-03-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 09-03-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Gene3D G3DSA:3.30.70.260 353 428 2.6E-7 T 09-03-2017 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 SUPERFAMILY SSF51735 5 159 2.01E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 SUPERFAMILY SSF55021 353 430 1.78E-10 T 09-03-2017 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 PIRSF PIRSF000098 4 438 4.4E-158 T 09-03-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Gene3D G3DSA:3.30.360.10 150 305 9.9E-58 T 09-03-2017 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Gene3D G3DSA:3.40.50.720 4 149 9.2E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Pfam PF01842 ACT domain 354 423 2.2E-11 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 SUPERFAMILY SSF55347 138 308 9.15E-55 T 09-03-2017 ARZXY2_RS05170 65c9da46e0a66b12ee66d8a093681216 438 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 130 8.6E-20 T 09-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 ARZXY2_RS00995 855e7424ff1c730ecfc7cd396bdbf9ac 242 Gene3D G3DSA:3.40.50.150 55 239 3.7E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS00995 855e7424ff1c730ecfc7cd396bdbf9ac 242 Pfam PF13649 Methyltransferase domain 76 168 7.0E-15 T 09-03-2017 ARZXY2_RS00995 855e7424ff1c730ecfc7cd396bdbf9ac 242 SUPERFAMILY SSF53335 38 202 3.07E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 Gene3D G3DSA:3.90.1150.10 259 363 1.9E-27 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 14 362 1.1E-90 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 Gene3D G3DSA:3.40.640.10 62 258 3.9E-53 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 09-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 SUPERFAMILY SSF53383 31 363 1.06E-72 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 364 53.162 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 ARZXY2_RS11335 e3475c80054a13e7e51d6c99f2b5bf84 367 Pfam PF00155 Aminotransferase class I and II 32 360 1.9E-53 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 PIRSF PIRSF000183 1 370 5.3E-168 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 SUPERFAMILY SSF52283 1 136 2.81E-63 T 09-03-2017 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 SUPERFAMILY SSF52283 304 359 2.81E-63 T 09-03-2017 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.4E-81 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 361 7.0E-170 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 SMART SM01003 4 136 1.1E-74 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 SMART SM01002 148 296 2.3E-89 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 Gene3D G3DSA:3.40.50.1770 3 187 5.1E-62 T 09-03-2017 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 SUPERFAMILY SSF51735 136 302 5.71E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 136 2.7E-46 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 09-03-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 ARZXY2_RS07215 0a0ea0c27f49315d4cf74fa37bc412c1 371 Gene3D G3DSA:3.40.50.1770 188 356 1.8E-31 T 09-03-2017 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 SUPERFAMILY SSF88659 90 161 2.06E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 Pfam PF08281 Sigma-70, region 4 110 160 2.9E-9 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 SUPERFAMILY SSF54427 169 291 7.72E-11 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 160 1.8E-12 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 SUPERFAMILY SSF88946 10 72 1.14E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 Gene3D G3DSA:3.10.450.50 171 291 1.3E-9 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 Gene3D G3DSA:1.10.1740.10 12 73 4.2E-10 T 09-03-2017 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 Pfam PF04542 Sigma-70 region 2 12 73 8.6E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00600 2adf6b6d7bdb5c897d6fa2df647247e5 294 Gene3D G3DSA:1.10.10.10 104 160 1.7E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16870 1e4ea06d31866b8b0bdf1ce4a3e9885b 263 SMART SM00797 20 263 1.7E-21 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS16870 1e4ea06d31866b8b0bdf1ce4a3e9885b 263 Pfam PF02626 Allophanate hydrolase subunit 2 20 260 7.1E-49 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 4.0E-56 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 Gene3D G3DSA:3.30.420.40 1 253 2.7E-107 T 09-03-2017 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 496 1.7E-213 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 PIRSF PIRSF000538 3 499 3.0E-187 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 1.4E-82 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 57.088 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 Gene3D G3DSA:3.30.420.40 254 497 2.5E-94 T 09-03-2017 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 SUPERFAMILY SSF53067 4 255 4.7E-99 T 09-03-2017 ARZXY2_RS00790 c6f8ae67d5d5228a84812f9569f4ec25 499 SUPERFAMILY SSF53067 255 497 2.59E-82 T 09-03-2017 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 284 2.2E-88 T 09-03-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 Gene3D G3DSA:3.90.1170.20 4 134 1.6E-43 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 Gene3D G3DSA:3.20.20.70 135 275 2.2E-54 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 SUPERFAMILY SSF51690 114 284 9.81E-53 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 284 2.9E-54 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 PIRSF PIRSF006250 7 288 3.1E-81 T 09-03-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 SUPERFAMILY SSF54675 4 112 3.34E-27 T 09-03-2017 ARZXY2_RS05525 afe6e44637dd00c867f95c3c46875414 298 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 112 3.2E-22 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 Gene3D G3DSA:1.50.10.10 242 348 1.1E-7 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 PIRSF PIRSF006402 8 717 1.0E-176 T 09-03-2017 IPR024705 Spermatogenesis-associated protein 20 ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 Pfam PF03190 Protein of unknown function, DUF255 19 177 1.5E-67 T 09-03-2017 IPR004879 Domain of unknown function DUF255 ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 SUPERFAMILY SSF52833 15 142 8.4E-26 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 Gene3D G3DSA:3.40.30.10 37 163 2.0E-28 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS12995 4b15929ad3cade6800e2364c5d35e55a 717 SUPERFAMILY SSF48208 209 537 1.97E-46 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS14520 03fec738ac0c243a588123ca2763bf32 141 Pfam PF02050 Flagellar FliJ protein 20 134 2.4E-8 T 09-03-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 Gene3D G3DSA:3.40.50.300 12 205 3.7E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 PRINTS PR00988 Uridine kinase signature 51 62 4.0E-9 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 PRINTS PR00988 Uridine kinase signature 192 205 4.0E-9 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 PRINTS PR00988 Uridine kinase signature 22 39 4.0E-9 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 PRINTS PR00988 Uridine kinase signature 158 168 4.0E-9 T 09-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 ARZXY2_RS09470 f4041bde32c48a3b404c67dc89ca46d6 208 SUPERFAMILY SSF52540 21 207 3.77E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 Gene3D G3DSA:3.40.50.720 7 190 2.6E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 SUPERFAMILY SSF48179 189 286 1.19E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 187 2.6E-53 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 285 7.5E-27 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 Gene3D G3DSA:1.10.1040.10 191 285 1.5E-29 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 SUPERFAMILY SSF51735 11 189 2.48E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02285 2e30b6a5644b957d47580e97416cedcb 287 PIRSF PIRSF000105 3 287 5.3E-74 T 09-03-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF81665 563 573 1.11E-14 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF81665 245 290 1.11E-14 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF81665 387 480 1.11E-14 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Pfam PF00403 Heavy-metal-associated domain 3 61 2.5E-10 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF81653 289 386 3.53E-28 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 225 793 3.8E-186 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Gene3D G3DSA:3.40.50.1000 612 752 8.2E-59 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Gene3D G3DSA:3.40.50.1000 457 500 8.2E-59 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Gene3D G3DSA:2.70.150.10 248 387 3.4E-31 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 488 494 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Gene3D G3DSA:3.40.1110.10 501 611 7.0E-23 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 794 4.4E-180 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 486 500 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 707 719 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 620 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 684 703 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 641 6.8E-31 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Pfam PF00702 haloacid dehalogenase-like hydrolase 482 698 7.9E-51 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF55008 2 70 2.36E-10 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF56784 484 504 4.79E-59 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 SUPERFAMILY SSF56784 542 791 4.79E-59 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 767 1.3E-92 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Gene3D G3DSA:3.30.70.100 2 62 2.9E-9 T 09-03-2017 ARZXY2_RS06110 0b70aecffb849e4adc14b601c47d4212 821 Pfam PF00122 E1-E2 ATPase 258 477 1.5E-64 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Gene3D G3DSA:3.40.50.300 418 505 2.6E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Gene3D G3DSA:3.40.50.300 342 376 2.6E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SMART SM00490 403 495 6.0E-10 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Pfam PF08148 DSHCT (NUC185) domain 817 980 4.3E-37 T 09-03-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SMART SM00487 35 217 1.8E-32 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Gene3D G3DSA:3.40.50.300 36 220 5.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SMART SM01142 813 985 1.7E-63 T 09-03-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Pfam PF13234 rRNA-processing arch domain 552 658 8.4E-5 T 09-03-2017 IPR025696 rRNA-processing arch domain ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SUPERFAMILY SSF52540 50 190 2.17E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SUPERFAMILY SSF52540 321 373 2.17E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 SUPERFAMILY SSF52540 415 509 2.17E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08605 ed0bb0e21a4974db1c904df6fd258051 986 Pfam PF00270 DEAD/DEAH box helicase 41 189 4.2E-19 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 SUPERFAMILY SSF51905 367 439 9.08E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 SUPERFAMILY SSF51905 2 268 9.08E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Pfam PF00890 FAD binding domain 7 409 4.8E-112 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Pfam PF02910 Fumarate reductase flavoprotein C-term 463 599 7.7E-43 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Gene3D G3DSA:4.10.80.40 552 595 3.7E-13 T 09-03-2017 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Gene3D G3DSA:3.90.700.10 252 357 8.4E-40 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 599 2.3E-242 T 09-03-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 PIRSF PIRSF000171 1 584 2.1E-49 T 09-03-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 09-03-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Gene3D G3DSA:1.20.58.100 436 551 2.9E-37 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Gene3D G3DSA:3.50.50.60 359 429 8.5E-115 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 Gene3D G3DSA:3.50.50.60 2 251 8.5E-115 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 599 6.4E-276 T 09-03-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 SUPERFAMILY SSF46977 455 599 4.06E-45 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 SUPERFAMILY SSF56425 245 363 4.34E-41 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.9E-7 T 09-03-2017 ARZXY2_RS13215 37ecdea20298838d5db3d3962cd75c2f 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 372 394 4.9E-7 T 09-03-2017 ARZXY2_RS18885 278e98a6647b6a3170fe952cd9b8f025 445 SUPERFAMILY SSF103473 19 427 1.96E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18885 278e98a6647b6a3170fe952cd9b8f025 445 Pfam PF00083 Sugar (and other) transporter 28 218 8.4E-17 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS18885 278e98a6647b6a3170fe952cd9b8f025 445 Gene3D G3DSA:1.20.1250.20 241 430 8.2E-19 T 09-03-2017 ARZXY2_RS18885 278e98a6647b6a3170fe952cd9b8f025 445 Gene3D G3DSA:1.20.1250.20 27 217 2.3E-19 T 09-03-2017 ARZXY2_RS18885 278e98a6647b6a3170fe952cd9b8f025 445 Pfam PF07690 Major Facilitator Superfamily 254 431 2.1E-10 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS20585 d9925543a126249ed7bdd0de9cf5c62a 274 Pfam PF00005 ABC transporter 20 167 2.5E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS20585 d9925543a126249ed7bdd0de9cf5c62a 274 SUPERFAMILY SSF52540 3 229 1.17E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20585 d9925543a126249ed7bdd0de9cf5c62a 274 SMART SM00382 28 217 3.4E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS20585 d9925543a126249ed7bdd0de9cf5c62a 274 Gene3D G3DSA:3.40.50.300 3 236 2.7E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20585 d9925543a126249ed7bdd0de9cf5c62a 274 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02145 5eb0095f7521b2838f2b66146a115d05 221 SUPERFAMILY SSF53254 2 204 1.39E-35 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS02145 5eb0095f7521b2838f2b66146a115d05 221 SMART SM00855 5 165 4.6E-16 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS02145 5eb0095f7521b2838f2b66146a115d05 221 Gene3D G3DSA:3.40.50.1240 5 200 2.4E-29 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS02145 5eb0095f7521b2838f2b66146a115d05 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 200 4.9E-29 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 SUPERFAMILY SSF48179 173 277 1.19E-25 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 SUPERFAMILY SSF51735 9 170 1.22E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 Pfam PF10727 Rossmann-like domain 3 123 4.1E-50 T 09-03-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 Gene3D G3DSA:1.10.1040.20 172 274 1.3E-31 T 09-03-2017 IPR018931 Domain of unknown function DUF2520 ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 Pfam PF10728 Domain of unknown function (DUF2520) 140 270 9.5E-42 T 09-03-2017 IPR018931 Domain of unknown function DUF2520 ARZXY2_RS17955 3ca11f085533aa2e16b81e089c414c28 308 Gene3D G3DSA:3.40.50.720 8 170 2.6E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PIRSF PIRSF000097 1 267 1.0E-78 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 Pfam PF00248 Aldo/keto reductase family 18 261 4.0E-44 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 SUPERFAMILY SSF51430 7 265 9.95E-87 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 3.1E-44 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 3.1E-44 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 3.1E-44 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PRINTS PR00069 Aldo-keto reductase signature 93 111 3.1E-44 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 PRINTS PR00069 Aldo-keto reductase signature 37 61 3.1E-44 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 Gene3D G3DSA:3.20.20.100 6 264 1.5E-96 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17530 b6c98861805af0da0f57e116e7ef734f 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS11490 693b83e172310003e12ddeb7651f7c70 88 Pfam PF02597 ThiS family 3 88 2.0E-10 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 ARZXY2_RS11490 693b83e172310003e12ddeb7651f7c70 88 SUPERFAMILY SSF54285 3 86 1.72E-10 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp ARZXY2_RS11490 693b83e172310003e12ddeb7651f7c70 88 Gene3D G3DSA:3.10.20.30 3 88 8.5E-14 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS08320 f3e7cde4f2fa144aee3485dcd9b03d05 518 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 401 483 2.8E-10 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain ARZXY2_RS08320 f3e7cde4f2fa144aee3485dcd9b03d05 518 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 124 281 3.1E-42 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS08320 f3e7cde4f2fa144aee3485dcd9b03d05 518 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 123 281 2.1E-40 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS09250 86b5e2774c82f90eb4947ceeea3f1794 319 Pfam PF00005 ABC transporter 32 174 8.1E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS09250 86b5e2774c82f90eb4947ceeea3f1794 319 SMART SM00382 38 246 3.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09250 86b5e2774c82f90eb4947ceeea3f1794 319 Gene3D G3DSA:3.40.50.300 11 242 3.0E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09250 86b5e2774c82f90eb4947ceeea3f1794 319 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09250 86b5e2774c82f90eb4947ceeea3f1794 319 SUPERFAMILY SSF52540 12 241 4.52E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16370 3564fab6d9dbd58e7d4dff7270fd15ab 730 Pfam PF06202 Amylo-alpha-1,6-glucosidase 342 626 4.6E-6 T 09-03-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS16370 3564fab6d9dbd58e7d4dff7270fd15ab 730 SUPERFAMILY SSF48208 266 633 3.53E-81 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS16370 3564fab6d9dbd58e7d4dff7270fd15ab 730 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 20 199 2.4E-36 T 09-03-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 Gene3D G3DSA:3.40.50.620 26 233 3.3E-88 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 27 355 41.626 T 09-03-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 SUPERFAMILY SSF52374 29 354 2.64E-97 T 09-03-2017 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 168 189 2.2E-25 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 221 231 2.2E-25 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 91 110 2.2E-25 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 41 57 2.2E-25 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 Pfam PF00579 tRNA synthetases class I (W and Y) 27 308 1.6E-81 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 Gene3D G3DSA:1.10.240.10 234 322 4.5E-19 T 09-03-2017 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 27 354 2.1E-105 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 ARZXY2_RS13250 4038e98871b887155628767968b6e629 369 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 36 46 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 Gene3D G3DSA:3.90.45.10 4 187 3.5E-60 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 166 5.9E-38 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 Hamap MF_00163 Peptide deformylase [def]. 2 170 27.512 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 PRINTS PR01576 Peptide deformylase signature 97 108 1.3E-30 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 PRINTS PR01576 Peptide deformylase signature 33 62 1.3E-30 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 PRINTS PR01576 Peptide deformylase signature 109 127 1.3E-30 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 PRINTS PR01576 Peptide deformylase signature 128 157 1.3E-30 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 Pfam PF01327 Polypeptide deformylase 4 157 9.2E-43 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 PIRSF PIRSF004749 1 176 1.6E-44 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS07480 ebcb11cca794fbe370b78820b7b9bd77 190 SUPERFAMILY SSF56420 3 182 2.36E-54 T 09-03-2017 IPR023635 Peptide deformylase ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 SUPERFAMILY SSF51735 13 196 7.58E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 Gene3D G3DSA:1.10.1040.10 196 341 2.2E-49 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 SUPERFAMILY SSF48179 195 347 2.21E-49 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PIRSF PIRSF000114 9 348 3.6E-97 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 196 334 5.4E-45 T 09-03-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 13 176 3.4E-51 T 09-03-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 Gene3D G3DSA:3.40.50.720 12 195 1.1E-63 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 204 225 - T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 12 338 35.036 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 189 213 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 214 238 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 72 99 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 16 33 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 149 169 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS05770 d56f01bfb420f1b34bf7188048cfbca4 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 254 271 2.1E-45 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 SMART SM00382 37 230 1.5E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 SMART SM00382 315 509 1.9E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 SUPERFAMILY SSF52540 14 247 3.24E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 SUPERFAMILY SSF52540 298 492 2.61E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 Pfam PF00005 ABC transporter 29 181 1.2E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 Pfam PF00005 ABC transporter 308 454 1.2E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 Gene3D G3DSA:3.40.50.300 303 488 6.1E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00405 dbe749a0138862bdb589a78be634a0cd 513 Gene3D G3DSA:3.40.50.300 16 249 1.2E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 Gene3D G3DSA:1.20.1080.10 16 237 3.6E-45 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 Pfam PF00230 Major intrinsic protein 20 235 2.8E-36 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 SUPERFAMILY SSF81338 18 238 1.57E-44 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 ProSitePatterns PS00221 MIP family signature. 70 78 - T 09-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 179 201 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 218 238 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 17 36 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 148 166 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 52 76 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS05440 e59d4ae18fd4ab0f9e98195de2eb65ce 299 PRINTS PR00783 Major intrinsic protein family signature 89 108 2.3E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS19605 897305e29d5e24ac948ce4e8a5a5936c 470 Gene3D G3DSA:3.30.1330.90 11 162 9.8E-50 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS19605 897305e29d5e24ac948ce4e8a5a5936c 470 Pfam PF03315 Serine dehydratase beta chain 5 160 2.1E-52 T 09-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS19605 897305e29d5e24ac948ce4e8a5a5936c 470 Pfam PF03313 Serine dehydratase alpha chain 193 464 4.8E-102 T 09-03-2017 IPR005130 Serine dehydratase-like, alpha subunit ARZXY2_RS19605 897305e29d5e24ac948ce4e8a5a5936c 470 SUPERFAMILY SSF143548 17 161 1.94E-39 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS19605 897305e29d5e24ac948ce4e8a5a5936c 470 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 467 1.2E-196 T 09-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 Gene3D G3DSA:1.10.10.10 1 58 3.5E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 Gene3D G3DSA:3.40.50.1360 77 220 4.4E-17 T 09-03-2017 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 SMART SM01134 74 241 3.5E-59 T 09-03-2017 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 SUPERFAMILY SSF46785 5 59 5.62E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 SMART SM00420 6 58 5.4E-20 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 Pfam PF00455 DeoR C terminal sensor domain 78 240 1.4E-46 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.5E-18 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.8E-9 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.8E-9 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 SUPERFAMILY SSF100950 160 241 4.9E-32 T 09-03-2017 ARZXY2_RS01785 86fd6ca2964e564e5186b580b30753f9 264 SUPERFAMILY SSF100950 76 133 4.9E-32 T 09-03-2017 ARZXY2_RS01055 8b3df288e5c4f9d81a925285de5b31d0 294 SUPERFAMILY SSF109604 106 282 9.42E-26 T 09-03-2017 ARZXY2_RS01055 8b3df288e5c4f9d81a925285de5b31d0 294 Gene3D G3DSA:1.10.3210.10 114 220 2.9E-11 T 09-03-2017 IPR006674 HD domain ARZXY2_RS01055 8b3df288e5c4f9d81a925285de5b31d0 294 Pfam PF13223 Protein of unknown function (DUF4031) 3 75 3.7E-27 T 09-03-2017 IPR025109 Domain of unknown function DUF4031 ARZXY2_RS14495 d2433754e0aa1e4cd7322b51e057f70e 424 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 8 107 2.4E-22 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 ARZXY2_RS14495 d2433754e0aa1e4cd7322b51e057f70e 424 Pfam PF13657 HipA N-terminal domain 8 107 1.9E-20 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 ARZXY2_RS14495 d2433754e0aa1e4cd7322b51e057f70e 424 Pfam PF07804 HipA-like C-terminal domain 236 383 3.5E-26 T 09-03-2017 IPR012893 HipA-like, C-terminal ARZXY2_RS14495 d2433754e0aa1e4cd7322b51e057f70e 424 Pfam PF07805 HipA-like N-terminal domain 149 230 3.0E-14 T 09-03-2017 IPR012894 HipA, N-terminal subdomain 2 ARZXY2_RS02645 8c56e6e319aaca49bfc46a253e8affd1 384 Gene3D G3DSA:3.40.50.2000 204 366 2.4E-56 T 09-03-2017 ARZXY2_RS02645 8c56e6e319aaca49bfc46a253e8affd1 384 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 365 3.0E-114 T 09-03-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS02645 8c56e6e319aaca49bfc46a253e8affd1 384 SUPERFAMILY SSF53756 4 372 1.57E-125 T 09-03-2017 ARZXY2_RS02645 8c56e6e319aaca49bfc46a253e8affd1 384 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 365 2.0E-139 T 09-03-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 ARZXY2_RS02645 8c56e6e319aaca49bfc46a253e8affd1 384 Gene3D G3DSA:3.40.50.2000 4 203 9.2E-82 T 09-03-2017 ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 279 290 2.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 332 340 2.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 352 371 2.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 SUPERFAMILY SSF51735 102 190 1.54E-5 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 339 367 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 Gene3D G3DSA:3.40.50.720 197 443 3.4E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 213 440 1.2E-51 T 09-03-2017 ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 225 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 326 342 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 406 426 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 352 371 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 373 390 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 279 290 3.1E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 SUPERFAMILY SSF51735 200 444 8.63E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08820 41c7b5b0cb2bba184173a96a61e95bc3 446 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 207 383 1.4E-5 T 09-03-2017 ARZXY2_RS00830 f3513d623f96d7d076cd2cca00d946a5 350 Gene3D G3DSA:3.40.50.2300 40 159 1.1E-37 T 09-03-2017 ARZXY2_RS00830 f3513d623f96d7d076cd2cca00d946a5 350 Gene3D G3DSA:3.40.50.2300 160 331 4.1E-35 T 09-03-2017 ARZXY2_RS00830 f3513d623f96d7d076cd2cca00d946a5 350 Pfam PF13407 Periplasmic binding protein domain 41 309 1.4E-47 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS00830 f3513d623f96d7d076cd2cca00d946a5 350 SUPERFAMILY SSF53822 16 332 1.04E-58 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS12275 fb3d66e927e192ab09652f90cafdb5d8 307 SUPERFAMILY SSF53067 10 304 3.55E-45 T 09-03-2017 ARZXY2_RS12275 fb3d66e927e192ab09652f90cafdb5d8 307 Gene3D G3DSA:3.30.420.40 9 146 1.6E-33 T 09-03-2017 ARZXY2_RS12275 fb3d66e927e192ab09652f90cafdb5d8 307 Gene3D G3DSA:3.30.420.40 147 284 1.7E-30 T 09-03-2017 ARZXY2_RS12275 fb3d66e927e192ab09652f90cafdb5d8 307 Pfam PF00480 ROK family 11 299 2.5E-48 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Gene3D G3DSA:3.40.50.10490 265 464 1.0E-65 T 09-03-2017 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Pfam PF13522 Glutamine amidotransferase domain 73 172 4.9E-19 T 09-03-2017 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 SUPERFAMILY SSF53697 267 634 6.41E-100 T 09-03-2017 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 SUPERFAMILY SSF56235 2 253 2.32E-59 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Gene3D G3DSA:3.60.20.10 2 261 5.5E-68 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 634 6.3E-222 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Gene3D G3DSA:3.40.50.10490 465 634 1.2E-57 T 09-03-2017 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 634 38.059 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Pfam PF01380 SIS domain 483 615 2.9E-19 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS00835 11ffe25f4a8e6081ec9834f7218cc1bd 634 Pfam PF01380 SIS domain 314 432 3.7E-27 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS07545 3c25a5a81d48e8d86c1d8ca6febcdab6 341 Gene3D G3DSA:3.40.50.720 1 298 3.7E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07545 3c25a5a81d48e8d86c1d8ca6febcdab6 341 SUPERFAMILY SSF51735 1 305 1.44E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07545 3c25a5a81d48e8d86c1d8ca6febcdab6 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 204 7.6E-6 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 SUPERFAMILY SSF52009 123 236 3.4E-27 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 3.3E-12 T 09-03-2017 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 429 444 3.3E-12 T 09-03-2017 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 446 461 3.3E-12 T 09-03-2017 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Gene3D G3DSA:3.50.30.10 132 240 3.1E-30 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 124 1.7E-18 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 51 554 6.0E-106 T 09-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Gene3D G3DSA:1.10.274.10 37 131 3.7E-15 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Gene3D G3DSA:3.20.20.60 253 556 7.6E-83 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 PIRSF PIRSF000732 1 560 1.9E-144 T 09-03-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 222 9.0E-19 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 254 528 1.3E-71 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 SUPERFAMILY SSF51621 250 529 2.7E-76 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS20200 68846edea048d065906ed0bde8678e0e 566 SUPERFAMILY SSF47831 38 141 9.68E-17 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 SUPERFAMILY SSF101790 266 335 3.27E-5 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 SUPERFAMILY SSF103025 24 262 1.3E-55 T 09-03-2017 ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 211 272 6.9E-20 T 09-03-2017 IPR017703 YgfZ/GcvT conserved site ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 Pfam PF01571 Aminomethyltransferase folate-binding domain 23 141 6.5E-18 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 247 329 3.4E-8 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 Gene3D G3DSA:3.30.70.1400 48 132 2.2E-11 T 09-03-2017 ARZXY2_RS03335 8d209833c0a97008b7c3158e587f2846 361 Gene3D G3DSA:2.40.30.110 264 327 8.2E-5 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS06070 c885ff96702ad50c2b710bbf22d1c8b3 714 Pfam PF00293 NUDIX domain 523 603 1.9E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS06070 c885ff96702ad50c2b710bbf22d1c8b3 714 Gene3D G3DSA:3.60.110.10 269 426 1.2E-9 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS06070 c885ff96702ad50c2b710bbf22d1c8b3 714 SUPERFAMILY SSF55811 520 637 1.18E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS06070 c885ff96702ad50c2b710bbf22d1c8b3 714 SUPERFAMILY SSF56317 266 447 4.19E-14 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS06070 c885ff96702ad50c2b710bbf22d1c8b3 714 Gene3D G3DSA:3.90.79.10 513 638 8.9E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS10295 88dae4c683349334775e4f6bdcaf8cfd 214 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 91 7.5E-6 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 ARZXY2_RS10295 88dae4c683349334775e4f6bdcaf8cfd 214 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 6 207 7.7E-75 T 09-03-2017 IPR017519 Conserved hypothetical protein CHP03085 ARZXY2_RS10295 88dae4c683349334775e4f6bdcaf8cfd 214 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 189 6.8E-31 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 76 181 1.2E-14 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Gene3D G3DSA:3.20.20.80 291 599 6.6E-56 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Gene3D G3DSA:2.60.120.260 11 174 2.1E-58 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 SUPERFAMILY SSF51445 289 599 1.51E-55 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 291 456 5.5E-7 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 SUPERFAMILY SSF49785 9 184 7.05E-52 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Gene3D G3DSA:2.60.40.320 175 288 1.5E-17 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 Pfam PF00703 Glycosyl hydrolases family 2 186 284 1.2E-9 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ARZXY2_RS18270 4e6a83ff494312665cf31c122f44a48a 612 SUPERFAMILY SSF49303 186 286 6.33E-10 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.2E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.2E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 Gene3D G3DSA:3.40.50.720 1 242 5.6E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 PIRSF PIRSF000126 1 261 3.3E-78 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 4.9E-4 T 09-03-2017 ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 SUPERFAMILY SSF51735 1 244 1.92E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20430 4325321d560d67869da15cd8ae1062e0 262 Pfam PF00106 short chain dehydrogenase 9 197 1.8E-49 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS20100 1b1e2cb46a899960f64ecf3cf660c1d1 329 Gene3D G3DSA:1.10.3720.10 94 302 5.9E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20100 1b1e2cb46a899960f64ecf3cf660c1d1 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 302 4.1E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20100 1b1e2cb46a899960f64ecf3cf660c1d1 329 SUPERFAMILY SSF161098 95 286 2.88E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20100 1b1e2cb46a899960f64ecf3cf660c1d1 329 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 64 9.9E-12 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SMART SM00220 27 294 4.3E-61 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SUPERFAMILY SSF54184 555 615 4.06E-5 T 09-03-2017 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SMART SM00740 555 617 6.4E-9 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SMART SM00740 483 552 6.0E-8 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SMART SM00740 416 482 1.9E-9 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 154 166 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Pfam PF03793 PASTA domain 555 617 1.0E-13 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Pfam PF03793 PASTA domain 487 551 1.9E-10 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Pfam PF03793 PASTA domain 420 481 2.0E-8 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Gene3D G3DSA:1.10.510.10 119 295 6.3E-48 T 09-03-2017 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Gene3D G3DSA:3.30.200.20 16 115 1.1E-25 T 09-03-2017 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 SUPERFAMILY SSF56112 17 292 1.22E-72 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 Pfam PF00069 Protein kinase domain 27 285 1.6E-49 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS18445 89b6d663a7d3b20fd6e85294f2f26333 643 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 56 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 460 665 1.2E-67 T 09-03-2017 IPR017501 Phage infection protein, YhgE, C-terminal ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 Pfam PF12698 ABC-2 family transporter protein 463 657 7.0E-11 T 09-03-2017 ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 175 1.0E-50 T 09-03-2017 IPR017500 Phage infection protein, YhgE, N-terminal ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 199 226 2.4E-7 T 09-03-2017 IPR023908 xxxLxxG heptad repeat ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 229 253 1.1E-7 T 09-03-2017 IPR023908 xxxLxxG heptad repeat ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 405 432 2.2E-5 T 09-03-2017 IPR023908 xxxLxxG heptad repeat ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 373 397 1.6E-4 T 09-03-2017 IPR023908 xxxLxxG heptad repeat ARZXY2_RS15180 3e28565c656b9fdec80838be25cdff0e 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 185 205 1.3E-4 T 09-03-2017 IPR023908 xxxLxxG heptad repeat ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 SUPERFAMILY SSF47005 185 224 1.19E-9 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Pfam PF00364 Biotin-requiring enzyme 7 79 1.3E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Gene3D G3DSA:4.10.320.10 187 233 1.6E-15 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Gene3D G3DSA:3.30.559.10 263 487 2.3E-68 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Pfam PF02817 e3 binding domain 188 221 5.1E-11 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 263 487 1.5E-69 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 SUPERFAMILY SSF51230 6 96 5.89E-25 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 Gene3D G3DSA:2.40.50.100 6 96 3.9E-25 T 09-03-2017 ARZXY2_RS02675 c7ceaafb192a2b2b02b7c661613e606b 493 SUPERFAMILY SSF52777 264 487 1.07E-66 T 09-03-2017 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 2.1E-105 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 Gene3D G3DSA:3.40.50.10490 159 242 2.7E-68 T 09-03-2017 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 Gene3D G3DSA:3.40.50.10490 23 99 2.7E-68 T 09-03-2017 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 SUPERFAMILY SSF52313 6 226 1.24E-90 T 09-03-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 Gene3D G3DSA:1.10.287.610 100 153 1.8E-20 T 09-03-2017 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 09-03-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 Pfam PF00318 Ribosomal protein S2 9 225 5.2E-95 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 176 187 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 197 211 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 159 176 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.7E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11810 cebb098fc5824b2c231f9d8478307bc7 279 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 41.529 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS09670 48997f1dcaae26399699503873b66c90 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 2.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09670 48997f1dcaae26399699503873b66c90 229 Gene3D G3DSA:1.10.357.10 29 206 3.8E-18 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS09670 48997f1dcaae26399699503873b66c90 229 SUPERFAMILY SSF46689 29 93 2.77E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 ProSitePatterns PS00145 Urease active site. 320 336 - T 09-03-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Gene3D G3DSA:2.30.40.10 71 146 7.1E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 SUPERFAMILY SSF51338 433 486 9.42E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Gene3D G3DSA:2.30.40.10 427 464 1.3E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 SUPERFAMILY SSF51556 489 576 2.45E-191 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 SUPERFAMILY SSF51556 133 440 2.45E-191 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 410 425 3.6E-33 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 3.6E-33 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 3.6E-33 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 436 449 3.6E-33 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 09-03-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Gene3D G3DSA:3.20.20.140 497 574 3.7E-199 T 09-03-2017 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Gene3D G3DSA:3.20.20.140 147 426 3.7E-199 T 09-03-2017 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 5 576 1.9E-291 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 122 1.1E-53 T 09-03-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Hamap MF_01953 Urease subunit alpha [ureC]. 3 576 57.002 T 09-03-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 Pfam PF01979 Amidohydrolase family 128 461 1.4E-72 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS17580 f409c52c8aa3218ed69d36f9e19e6e61 576 SUPERFAMILY SSF51338 4 180 6.59E-58 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS03845 dfc2db67e12627b685b2b9ae1a99c18e 383 SUPERFAMILY SSF55931 3 378 3.73E-111 T 09-03-2017 ARZXY2_RS03845 dfc2db67e12627b685b2b9ae1a99c18e 383 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 383 101.017 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS03845 dfc2db67e12627b685b2b9ae1a99c18e 383 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 12 305 2.3E-101 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS03845 dfc2db67e12627b685b2b9ae1a99c18e 383 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 299 1.1E-66 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 Gene3D G3DSA:3.65.10.10 92 290 1.6E-36 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 78 495 2.1E-42 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 SMART SM00530 12 67 4.0E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 SUPERFAMILY SSF47413 4 64 8.85E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 Gene3D G3DSA:3.65.10.10 291 503 2.3E-40 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 Pfam PF01381 Helix-turn-helix 13 65 9.9E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 Gene3D G3DSA:1.10.260.40 4 66 1.5E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00430 68f014a23531eaaf5335792c9f772649 507 SUPERFAMILY SSF55205 72 506 3.6E-95 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:1.10.8.280 178 287 1.3E-27 T 09-03-2017 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 ProSitePatterns PS00211 ABC transporters family signature. 752 766 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 SUPERFAMILY SSF52540 338 463 7.25E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 SUPERFAMILY SSF52540 30 210 7.25E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 ProSitePatterns PS00211 ABC transporters family signature. 382 396 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 148 847 1.2E-219 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 SUPERFAMILY SSF52540 525 566 3.67E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 SUPERFAMILY SSF52540 606 834 3.67E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:1.20.1580.10 117 177 4.4E-30 T 09-03-2017 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:1.20.1580.10 288 372 4.4E-30 T 09-03-2017 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:1.20.1580.10 616 742 2.0E-46 T 09-03-2017 ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:3.40.50.300 28 75 5.8E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:3.40.50.300 514 577 1.8E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:3.40.50.300 373 486 5.8E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04195 b0fd5725ab794c947449b8b0ec76cef7 866 Gene3D G3DSA:3.40.50.300 743 861 1.8E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12210 b8764a770a58db441c38ef059d88eb37 76 Pfam PF13275 S4 domain 9 72 3.4E-26 T 09-03-2017 ARZXY2_RS12210 b8764a770a58db441c38ef059d88eb37 76 Gene3D G3DSA:3.10.290.10 4 72 7.2E-28 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS12210 b8764a770a58db441c38ef059d88eb37 76 SUPERFAMILY SSF55174 5 72 1.57E-18 T 09-03-2017 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 409 8.4E-130 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 ProSitePatterns PS00099 Thiolases active site. 392 405 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 09-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 SUPERFAMILY SSF53901 3 286 2.46E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Gene3D G3DSA:3.40.47.10 216 294 4.4E-54 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Gene3D G3DSA:3.40.47.10 4 130 4.4E-54 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 ProSitePatterns PS00737 Thiolases signature 2. 357 373 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 SUPERFAMILY SSF53901 289 410 1.22E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Gene3D G3DSA:3.40.47.10 177 215 3.9E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Gene3D G3DSA:3.40.47.10 295 410 3.9E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 PIRSF PIRSF000429 1 412 1.4E-120 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Pfam PF02803 Thiolase, C-terminal domain 289 410 1.2E-46 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS13050 502f742835220c67c90a42174c600b0b 412 Pfam PF00108 Thiolase, N-terminal domain 5 280 1.1E-57 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS07325 0c815d35fb72d50759c8ebffb64695e1 81 Gene3D G3DSA:1.10.1200.10 3 78 8.4E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS07325 0c815d35fb72d50759c8ebffb64695e1 81 Pfam PF00550 Phosphopantetheine attachment site 11 76 6.3E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS07325 0c815d35fb72d50759c8ebffb64695e1 81 SUPERFAMILY SSF47336 3 79 4.97E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS07325 0c815d35fb72d50759c8ebffb64695e1 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 76 8.0E-14 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS07325 0c815d35fb72d50759c8ebffb64695e1 81 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 16.497 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS06085 d3e642f7b4aa4b42a0256b085e56213f 226 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 102 185 6.6E-8 T 09-03-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 120 453 3.3E-111 T 09-03-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 SUPERFAMILY SSF51735 119 295 3.95E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 SMART SM00846 118 279 1.3E-49 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 119 279 1.3E-36 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 277 284 - T 09-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 291 6.0E-18 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 398 413 6.0E-18 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 356 373 6.0E-18 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 237 250 6.0E-18 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 300 316 6.0E-18 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 Gene3D G3DSA:3.40.50.720 119 287 7.4E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 SUPERFAMILY SSF55347 279 442 2.08E-55 T 09-03-2017 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 284 441 5.7E-49 T 09-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS07460 086844c9eaca8a96f274daa5b4f3137d 483 Gene3D G3DSA:3.30.360.10 288 443 2.0E-58 T 09-03-2017 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Gene3D G3DSA:3.40.50.300 220 372 6.1E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 4 999 0.0 T 09-03-2017 IPR010222 RNA helicase HrpA GO:0004004 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 SMART SM00487 9 197 5.8E-26 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 SMART SM00847 421 537 3.1E-31 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Pfam PF04408 Helicase associated domain (HA2) 423 524 3.6E-14 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Pfam PF00271 Helicase conserved C-terminal domain 234 356 3.4E-10 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 SMART SM00382 26 337 3.2E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Pfam PF11898 Domain of unknown function (DUF3418) 695 1321 1.3E-223 T 09-03-2017 IPR024590 RNA helicase HrpA, C-terminal ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 126 135 - T 09-03-2017 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Gene3D G3DSA:3.40.50.300 10 167 8.7E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 SMART SM00490 256 357 1.6E-12 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 601 682 3.8E-13 T 09-03-2017 IPR011709 Domain of unknown function DUF1605 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 Pfam PF00270 DEAD/DEAH box helicase 21 167 8.5E-6 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS05115 9fef5b02193f3ca99ee02cfab620b24e 1327 SUPERFAMILY SSF52540 8 576 4.59E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 317 4.7E-7 T 09-03-2017 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 220 4.7E-7 T 09-03-2017 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.7E-7 T 09-03-2017 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 SUPERFAMILY SSF51905 10 407 2.07E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 326 1.2E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 Gene3D G3DSA:3.50.50.60 207 309 6.6E-10 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17675 21f2723e74954edccedd8c2096a86268 465 Gene3D G3DSA:3.50.50.60 10 206 2.9E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 PIRSF PIRSF002131 3 133 3.6E-53 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 Gene3D G3DSA:3.30.420.80 13 133 2.1E-55 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 4.7E-57 T 09-03-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 Pfam PF00411 Ribosomal protein S11 23 132 6.7E-47 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 133 33.165 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 09-03-2017 IPR018102 Ribosomal S11, conserved site ARZXY2_RS03665 67efb783a91f76b750b45bbef5b6d8c9 133 SUPERFAMILY SSF53137 18 133 9.59E-48 T 09-03-2017 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 SUPERFAMILY SSF51905 336 396 6.28E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 SUPERFAMILY SSF51905 7 241 6.28E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 9 382 6.9E-86 T 09-03-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 Gene3D G3DSA:3.30.9.10 225 334 1.6E-7 T 09-03-2017 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 SUPERFAMILY SSF54373 239 335 6.54E-13 T 09-03-2017 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 Pfam PF01266 FAD dependent oxidoreductase 8 377 2.9E-42 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 Gene3D G3DSA:3.50.50.60 3 86 1.6E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 Gene3D G3DSA:3.50.50.60 336 398 1.6E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04420 1470dd79e12f4b3d92e87d8458183040 419 Gene3D G3DSA:3.50.50.60 144 224 1.6E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 13 399 1.0E-180 T 09-03-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 SUPERFAMILY SSF53383 25 401 4.57E-109 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 Gene3D G3DSA:3.40.640.10 11 260 4.2E-83 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 PIRSF PIRSF001434 4 402 1.6E-116 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 14 400 52.139 T 09-03-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 400 2.3E-126 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS00445 c7b5ff3ba9023778afc77e4f5f2f8958 402 Gene3D G3DSA:3.90.1150.10 263 402 2.5E-45 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 SUPERFAMILY SSF54637 69 165 4.23E-5 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 Gene3D G3DSA:3.10.129.10 188 302 1.2E-19 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 PRINTS PR01483 Fatty acid synthase signature 219 240 4.2E-8 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 PRINTS PR01483 Fatty acid synthase signature 197 219 4.2E-8 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 Pfam PF01575 MaoC like domain 181 280 4.0E-15 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS08815 06f5dc124f9e657528d5898b501ec366 306 SUPERFAMILY SSF54637 190 298 1.12E-16 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS17060 67d04b2ea1da9256fe931f7a30a5610e 506 SUPERFAMILY SSF53720 27 498 1.44E-159 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17060 67d04b2ea1da9256fe931f7a30a5610e 506 Gene3D G3DSA:3.40.309.10 289 473 2.5E-65 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS17060 67d04b2ea1da9256fe931f7a30a5610e 506 Gene3D G3DSA:3.40.605.10 29 288 2.4E-93 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17060 67d04b2ea1da9256fe931f7a30a5610e 506 Pfam PF00171 Aldehyde dehydrogenase family 38 497 2.1E-164 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS17060 67d04b2ea1da9256fe931f7a30a5610e 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 274 281 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 SUPERFAMILY SSF52172 9 140 7.12E-44 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 Gene3D G3DSA:1.10.10.10 139 236 9.0E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 SMART SM00448 15 125 3.0E-45 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 SMART SM00862 160 235 7.2E-29 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 SUPERFAMILY SSF46894 142 235 1.64E-29 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 Gene3D G3DSA:3.40.50.2300 15 133 5.0E-41 T 09-03-2017 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 235 9.8E-28 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS11480 121d6bbbb33030cfe6f51175e7cb2fc4 244 Pfam PF00072 Response regulator receiver domain 17 125 4.1E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 SUPERFAMILY SSF55021 337 403 1.87E-7 T 09-03-2017 ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 Gene3D G3DSA:3.40.50.1100 76 330 2.0E-77 T 09-03-2017 ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 SUPERFAMILY SSF53686 10 320 7.6E-98 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 313 2.5E-82 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 28 407 1.4E-140 T 09-03-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 Gene3D G3DSA:3.30.70.260 334 402 2.9E-10 T 09-03-2017 ARZXY2_RS13025 d96d230397bb4fccb4109361a644cc7e 412 Pfam PF01842 ACT domain 337 404 2.0E-7 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Gene3D G3DSA:3.40.50.360 20 174 2.4E-42 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 SUPERFAMILY SSF52218 30 176 1.22E-43 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 SUPERFAMILY SSF63380 199 415 4.12E-50 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Pfam PF00175 Oxidoreductase NAD-binding domain 427 531 3.7E-15 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Pfam PF00667 FAD binding domain 310 394 1.2E-13 T 09-03-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Pfam PF00667 FAD binding domain 201 268 2.7E-13 T 09-03-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00369 Flavodoxin signature 31 44 1.4E-10 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00369 Flavodoxin signature 135 154 1.4E-10 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00369 Flavodoxin signature 111 121 1.4E-10 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00369 Flavodoxin signature 79 90 1.4E-10 T 09-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Gene3D G3DSA:1.20.990.10 249 353 9.7E-16 T 09-03-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Gene3D G3DSA:3.40.50.80 425 568 1.5E-50 T 09-03-2017 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Pfam PF00258 Flavodoxin 32 155 6.7E-30 T 09-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 SUPERFAMILY SSF52343 414 568 9.82E-46 T 09-03-2017 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Gene3D G3DSA:2.40.30.10 354 424 4.6E-33 T 09-03-2017 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 Gene3D G3DSA:2.40.30.10 197 248 4.6E-33 T 09-03-2017 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 389 398 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 238 248 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 356 363 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 426 445 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 464 475 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 518 526 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 451 460 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS07160 ae4998e989a2452ab4f5c8d213d5fca0 568 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 495 511 2.7E-25 T 09-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 SMART SM00861 19 194 1.1E-65 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 Gene3D G3DSA:3.40.50.920 220 342 6.5E-43 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 SUPERFAMILY SSF52518 19 197 3.63E-63 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 Pfam PF02780 Transketolase, C-terminal domain 219 338 9.7E-38 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 Gene3D G3DSA:3.40.50.970 19 201 4.2E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 Pfam PF02779 Transketolase, pyrimidine binding domain 19 192 3.3E-45 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS05490 0a8dc4c747cdd6a72af38f2ff027bbd0 351 SUPERFAMILY SSF52922 217 347 4.32E-39 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS02090 8ed6399b39443173f4627d4ed47f1b90 235 ProDom PD113327 YESU 3D-STRUCTURE 6 223 1.0E-80 T 09-03-2017 IPR015305 Protein of unknown function DUF1961 ARZXY2_RS02090 8ed6399b39443173f4627d4ed47f1b90 235 SUPERFAMILY SSF49899 5 225 1.74E-91 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS02090 8ed6399b39443173f4627d4ed47f1b90 235 Pfam PF09224 Domain of unknown function (DUF1961) 6 223 2.4E-88 T 09-03-2017 IPR015305 Protein of unknown function DUF1961 ARZXY2_RS02090 8ed6399b39443173f4627d4ed47f1b90 235 Gene3D G3DSA:2.60.120.200 5 224 1.2E-85 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 SUPERFAMILY SSF46785 12 100 1.78E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 SMART SM00345 19 77 1.9E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 Gene3D G3DSA:1.20.120.530 81 217 4.8E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 SMART SM00895 87 211 1.0E-21 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 SUPERFAMILY SSF48008 83 217 4.97E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 Pfam PF07729 FCD domain 87 210 5.6E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 Gene3D G3DSA:1.10.10.10 11 74 2.6E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.5E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.5E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18900 a4ab9318501920c62857ca28ea727473 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 71 5.7E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 SUPERFAMILY SSF51338 1 56 1.92E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 SUPERFAMILY SSF51338 370 443 1.92E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 Gene3D G3DSA:3.20.20.140 65 388 8.8E-103 T 09-03-2017 ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 SUPERFAMILY SSF51556 56 369 6.81E-94 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 Pfam PF01979 Amidohydrolase family 53 395 1.5E-54 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS01600 4fcedd0dd4f76eac763a02a718e1b4c3 446 Gene3D G3DSA:2.30.40.10 12 64 1.7E-7 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 SUPERFAMILY SSF51556 74 384 5.88E-77 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 Pfam PF01979 Amidohydrolase family 71 411 5.6E-14 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 PIRSF PIRSF038994 57 414 1.5E-85 T 09-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 Gene3D G3DSA:3.20.20.140 79 383 2.1E-89 T 09-03-2017 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 Gene3D G3DSA:2.30.40.10 11 78 1.4E-5 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 SUPERFAMILY SSF51338 384 413 9.18E-8 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS05290 2fb0ce137b2ea9390de74d9c734d79d3 414 SUPERFAMILY SSF51338 14 73 9.18E-8 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SMART SM00382 42 447 8.9E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Pfam PF08494 DEAD/H associated 744 932 1.1E-75 T 09-03-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Gene3D G3DSA:3.40.50.300 16 245 3.0E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SUPERFAMILY SSF52540 273 327 9.81E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SUPERFAMILY SSF52540 391 464 9.81E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SUPERFAMILY SSF52540 38 231 9.81E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SMART SM00487 25 264 8.9E-38 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Gene3D G3DSA:3.40.50.300 391 505 5.2E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Gene3D G3DSA:3.40.50.300 301 327 5.2E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 SMART SM00490 379 460 4.9E-13 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Pfam PF00271 Helicase conserved C-terminal domain 396 460 1.7E-11 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS15320 263f2855da736cc8712e160fe2b5d934 1674 Pfam PF00270 DEAD/DEAH box helicase 30 231 3.2E-26 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 330 391 2.6E-13 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Pfam PF00970 Oxidoreductase FAD-binding domain 18 124 2.7E-8 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Gene3D G3DSA:3.40.50.80 116 279 6.1E-35 T 09-03-2017 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 SUPERFAMILY SSF63380 14 124 8.11E-19 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Gene3D G3DSA:3.10.20.30 280 399 1.7E-27 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 348 356 - T 09-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Pfam PF00175 Oxidoreductase NAD-binding domain 159 267 9.1E-15 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 SUPERFAMILY SSF52343 153 286 4.58E-30 T 09-03-2017 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 Gene3D G3DSA:2.40.30.10 13 115 4.0E-21 T 09-03-2017 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 15 400 1.7E-146 T 09-03-2017 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 ARZXY2_RS02405 86b48c423355232ec69b816990456611 401 SUPERFAMILY SSF54292 277 399 5.51E-25 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 TIGRFAM TIGR00613 reco: DNA repair protein RecO 13 246 3.8E-31 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 Gene3D G3DSA:2.40.50.140 10 88 2.5E-35 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 Pfam PF02565 Recombination protein O C terminal 94 245 1.0E-32 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 Pfam PF11967 Recombination protein O N terminal 12 82 5.1E-23 T 09-03-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 SUPERFAMILY SSF50249 10 85 6.0E-19 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 SUPERFAMILY SSF57863 91 240 8.89E-38 T 09-03-2017 ARZXY2_RS08335 d02233b370d1d1f6cefdcd0dc51c9a30 251 Hamap MF_00201 DNA repair protein RecO [recO]. 10 251 25.616 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 ARZXY2_RS07820 c6bce71bcdbc7c84c630dd1de489e377 113 Gene3D G3DSA:3.30.70.1060 1 108 2.2E-16 T 09-03-2017 ARZXY2_RS07820 c6bce71bcdbc7c84c630dd1de489e377 113 SUPERFAMILY SSF54909 2 108 3.7E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Gene3D G3DSA:3.40.50.1220 184 337 5.6E-51 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 SUPERFAMILY SSF52518 1 181 5.19E-47 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 4.2E-31 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Gene3D G3DSA:3.40.50.970 2 182 6.1E-59 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 588 0.0 T 09-03-2017 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 2.0E-52 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 SUPERFAMILY SSF52467 186 376 1.8E-48 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 SUPERFAMILY SSF52518 369 572 7.0E-49 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Gene3D G3DSA:3.40.50.970 360 581 1.3E-56 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01230 17ca297f6623030db24cbf7e087a9796 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 5.2E-35 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 SUPERFAMILY SSF103473 8 433 8.76E-78 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 Pfam PF07690 Major Facilitator Superfamily 24 381 1.6E-43 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 Gene3D G3DSA:1.20.1250.20 253 435 2.2E-30 T 09-03-2017 ARZXY2_RS09420 66d2756a06595d95624aaa3755eda123 452 Gene3D G3DSA:1.20.1250.20 20 198 5.1E-26 T 09-03-2017 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 793 0.0 T 09-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Gene3D G3DSA:3.50.30.10 372 472 1.9E-34 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 09-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 700 718 - T 09-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Gene3D G3DSA:3.20.20.60 480 793 1.5E-99 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 PIRSF PIRSF000854 1 800 0.0 T 09-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Gene3D G3DSA:3.30.470.20 195 353 4.8E-54 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 342 5.5E-115 T 09-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 SUPERFAMILY SSF52009 348 466 1.07E-33 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 SUPERFAMILY SSF56059 3 383 6.27E-108 T 09-03-2017 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 SUPERFAMILY SSF51621 461 795 6.54E-95 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 469 792 4.1E-59 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 1.5E-25 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS09410 072737790f07ea944f717da01c146341 800 Gene3D G3DSA:3.30.1490.20 4 192 3.5E-69 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 Pfam PF00171 Aldehyde dehydrogenase family 516 937 6.1E-109 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 720 727 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 SUPERFAMILY SSF51730 138 470 6.67E-72 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 Pfam PF01619 Proline dehydrogenase 142 432 3.8E-61 T 09-03-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 Gene3D G3DSA:3.40.309.10 735 926 4.4E-46 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 Gene3D G3DSA:3.20.20.220 136 470 5.2E-67 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 748 759 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 SUPERFAMILY SSF53720 514 941 2.09E-104 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 Gene3D G3DSA:3.40.605.10 516 734 7.1E-49 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15775 58e864cf1259f99bff3fbd98d3211728 1153 PIRSF PIRSF000197 16 1151 1.1E-269 T 09-03-2017 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 SUPERFAMILY SSF90123 5 314 1.44E-70 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 SUPERFAMILY SSF52540 328 571 1.07E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 Pfam PF00664 ABC transporter transmembrane region 18 288 4.6E-45 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 Gene3D G3DSA:1.20.1560.10 5 312 6.4E-63 T 09-03-2017 ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 Gene3D G3DSA:3.40.50.300 335 565 5.8E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 SMART SM00382 361 547 8.1E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01425 0b5112d2b83021f34e5e9858b202ca25 578 Pfam PF00005 ABC transporter 352 499 5.2E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS09140 c7481790045d1d2c13e52cf00fc29537 170 Gene3D G3DSA:3.40.630.30 3 155 3.3E-58 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09140 c7481790045d1d2c13e52cf00fc29537 170 Pfam PF00583 Acetyltransferase (GNAT) family 59 136 1.4E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS09140 c7481790045d1d2c13e52cf00fc29537 170 SUPERFAMILY SSF55729 3 151 4.73E-37 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS11620 2d3dfea88c2f9da6251ca5ad2cb52939 443 Gene3D G3DSA:2.30.42.10 125 242 2.5E-20 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS11620 2d3dfea88c2f9da6251ca5ad2cb52939 443 SUPERFAMILY SSF50156 130 242 7.1E-15 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS11620 2d3dfea88c2f9da6251ca5ad2cb52939 443 Pfam PF13180 PDZ domain 186 241 1.2E-8 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS11620 2d3dfea88c2f9da6251ca5ad2cb52939 443 Pfam PF02163 Peptidase family M50 14 395 1.1E-45 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 ARZXY2_RS10945 71b72257ee1d6a672e18d84ee12e335e 267 SUPERFAMILY SSF53474 15 246 3.38E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10945 71b72257ee1d6a672e18d84ee12e335e 267 PIRSF PIRSF017388 6 248 7.7E-57 T 09-03-2017 IPR012354 Esterase/lipase GO:0052689 ARZXY2_RS10945 71b72257ee1d6a672e18d84ee12e335e 267 Pfam PF12146 Serine aminopeptidase, S33 19 230 2.6E-14 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS10945 71b72257ee1d6a672e18d84ee12e335e 267 Gene3D G3DSA:3.40.50.1820 15 247 1.9E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19550 49fc332e8e3b6e3b839f0c69f32b8ec3 242 PIRSF PIRSF015736 1 242 8.1E-73 T 09-03-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase ARZXY2_RS19550 49fc332e8e3b6e3b839f0c69f32b8ec3 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 223 7.3E-9 T 09-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 Gene3D G3DSA:3.40.50.720 20 161 7.2E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 SUPERFAMILY SSF55347 169 310 2.05E-9 T 09-03-2017 ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 Pfam PF14100 Methane oxygenase PmoA 420 673 1.7E-61 T 09-03-2017 IPR029475 Methane oxygenase PmoA ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 24 143 9.2E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 SUPERFAMILY SSF51735 18 156 5.13E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02055 4995fa0b83c4f3bcc5d59f0d96a5da89 674 Gene3D G3DSA:3.30.360.10 175 348 7.1E-15 T 09-03-2017 ARZXY2_RS02825 c202fa39fbb228ce760265153e440cae 288 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 23 92 2.5E-8 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin ARZXY2_RS08765 404cb4df45b9708d5dfcda381f1101ad 220 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 141 172 9.4E-5 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS08765 404cb4df45b9708d5dfcda381f1101ad 220 SUPERFAMILY SSF51161 90 210 4.02E-33 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS08765 404cb4df45b9708d5dfcda381f1101ad 220 Gene3D G3DSA:2.160.10.10 94 210 2.5E-28 T 09-03-2017 ARZXY2_RS08765 404cb4df45b9708d5dfcda381f1101ad 220 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 206 3.1E-57 T 09-03-2017 IPR020019 Sialic acid O-acyltransferase NeuD-like ARZXY2_RS08765 404cb4df45b9708d5dfcda381f1101ad 220 Gene3D G3DSA:3.40.50.20 1 85 2.7E-8 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 164 5.4E-15 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 SUPERFAMILY SSF88659 110 163 9.35E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 Pfam PF08281 Sigma-70, region 4 110 160 2.2E-15 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 Gene3D G3DSA:1.10.10.10 110 164 2.0E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 Pfam PF04542 Sigma-70 region 2 27 86 2.4E-4 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 Gene3D G3DSA:1.10.1740.10 16 86 5.7E-8 T 09-03-2017 ARZXY2_RS18990 419d796b33715af14c7b48bb540a781b 175 SUPERFAMILY SSF88946 15 83 8.63E-8 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 SUPERFAMILY SSF46785 2 61 2.6E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 9.4E-15 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 9.4E-15 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 9.4E-15 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 09-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 1.9E-16 T 09-03-2017 ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 Gene3D G3DSA:1.10.10.10 3 53 7.8E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 7.4E-19 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 Gene3D G3DSA:3.30.70.920 55 150 6.5E-26 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 SUPERFAMILY SSF54909 62 150 7.37E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS20410 4c9ac3c07a5ac98a51769796a05d0395 151 SMART SM00344 2 111 2.8E-40 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS18245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS18245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS18245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS19930 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS19930 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS19930 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS17245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS17245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS17245 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS05725 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS05725 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS05725 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS17820 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS17820 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS17820 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS17935 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS17935 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS17935 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS08295 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS08295 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS08295 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS19655 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS19655 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS19655 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS14660 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS14660 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS14660 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS09700 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF01610 Transposase 182 419 2.9E-48 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS09700 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 44 86 1.2E-8 T 09-03-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger ARZXY2_RS09700 5c20fd32269fd2e9a9a6253828502c15 429 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 101 147 1.3E-7 T 09-03-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 Gene3D G3DSA:3.40.190.10 175 247 5.9E-4 T 09-03-2017 ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 44 253 4.1E-39 T 09-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 Gene3D G3DSA:3.40.190.10 35 165 5.3E-41 T 09-03-2017 ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 SUPERFAMILY SSF53850 38 258 6.76E-56 T 09-03-2017 ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 PIRSF PIRSF004846 2 259 9.0E-67 T 09-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 ARZXY2_RS01070 0d6090c68740700fc36eef2c4f118131 259 Pfam PF13531 Bacterial extracellular solute-binding protein 39 256 1.2E-43 T 09-03-2017 ARZXY2_RS00970 2eb845eb6039258ddb49049de21220f2 301 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 30 301 28.513 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ARZXY2_RS00970 2eb845eb6039258ddb49049de21220f2 301 Pfam PF02390 Putative methyltransferase 80 225 3.6E-46 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ARZXY2_RS00970 2eb845eb6039258ddb49049de21220f2 301 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 71 222 1.8E-44 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 ARZXY2_RS00970 2eb845eb6039258ddb49049de21220f2 301 Gene3D G3DSA:3.40.50.150 74 201 3.8E-7 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS00970 2eb845eb6039258ddb49049de21220f2 301 SUPERFAMILY SSF53335 68 219 3.84E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 Gene3D G3DSA:1.10.357.10 9 188 2.7E-32 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.3E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 SUPERFAMILY SSF48498 114 187 6.04E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS16840 8382911baf88e3abab47585c06dea368 209 SUPERFAMILY SSF46689 8 89 8.74E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12190 cd8590e9373cee3ee14cfe1f7d504b94 488 Pfam PF07907 YibE/F-like protein 166 404 1.7E-72 T 09-03-2017 IPR012507 YibE/F-like ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 SUPERFAMILY SSF53720 42 453 2.75E-110 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 50 443 3.1E-145 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 Gene3D G3DSA:3.40.605.10 35 260 2.0E-100 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 Gene3D G3DSA:3.40.605.10 412 453 2.0E-100 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 PIRSF PIRSF000151 34 454 2.0E-167 T 09-03-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 41 453 40.44 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 Pfam PF00171 Aldehyde dehydrogenase family 32 324 1.5E-12 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 Gene3D G3DSA:3.40.309.10 263 411 1.5E-40 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS07690 97c9d6d8b1b9de002e899efff4865ba0 454 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 360 381 - T 09-03-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 Pfam PF00268 Ribonucleotide reductase, small chain 14 285 1.6E-91 T 09-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 Gene3D G3DSA:1.10.620.20 3 285 3.6E-95 T 09-03-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 102 118 - T 09-03-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 12 324 6.5E-148 T 09-03-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 PIRSF PIRSF000355 2 321 1.1E-82 T 09-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07805 001c0c666ac22d4e26688e1edd1661c8 324 SUPERFAMILY SSF47240 10 324 1.27E-107 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS14150 5cf0e201a3f1fa4e47509610c8d33f02 132 Pfam PF00293 NUDIX domain 5 117 1.0E-16 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS14150 5cf0e201a3f1fa4e47509610c8d33f02 132 SUPERFAMILY SSF55811 3 120 3.66E-23 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS14150 5cf0e201a3f1fa4e47509610c8d33f02 132 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS14150 5cf0e201a3f1fa4e47509610c8d33f02 132 Gene3D G3DSA:3.90.79.10 2 114 5.4E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 SUPERFAMILY SSF50129 1 161 3.8E-55 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 SMART SM00829 8 349 2.4E-5 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 SUPERFAMILY SSF51735 144 314 1.48E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 136 6.7E-28 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 Gene3D G3DSA:3.90.180.10 1 177 6.6E-54 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 Gene3D G3DSA:3.40.50.720 178 292 1.9E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09835 eecec382dfea3f284e45270f5e1f7eb8 355 Pfam PF00107 Zinc-binding dehydrogenase 183 309 1.7E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 SUPERFAMILY SSF101898 333 521 4.97E-30 T 09-03-2017 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 SUPERFAMILY SSF101898 167 279 4.97E-30 T 09-03-2017 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 SUPERFAMILY SSF52833 23 177 5.95E-29 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Pfam PF01436 NHL repeat 448 475 2.0E-4 T 09-03-2017 IPR001258 NHL repeat GO:0005515 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Pfam PF01436 NHL repeat 389 414 1.0E-4 T 09-03-2017 IPR001258 NHL repeat GO:0005515 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Gene3D G3DSA:2.120.10.30 332 520 7.0E-47 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Gene3D G3DSA:2.120.10.30 176 280 7.0E-47 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Pfam PF00578 AhpC/TSA family 23 132 5.9E-9 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS00050 0fbd28a8fc67ae0a01808a99e2c61cbc 661 Gene3D G3DSA:3.40.30.10 13 156 4.5E-38 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS11795 20a4d8d69e76edb7821b6666f9df7ddf 185 Gene3D G3DSA:1.10.132.20 66 185 1.8E-38 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 ARZXY2_RS11795 20a4d8d69e76edb7821b6666f9df7ddf 185 Pfam PF01765 Ribosome recycling factor 21 183 4.3E-58 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 ARZXY2_RS11795 20a4d8d69e76edb7821b6666f9df7ddf 185 SUPERFAMILY SSF55194 3 184 1.44E-66 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 ARZXY2_RS11795 20a4d8d69e76edb7821b6666f9df7ddf 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 2.1E-63 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 ARZXY2_RS11795 20a4d8d69e76edb7821b6666f9df7ddf 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.177 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 ARZXY2_RS04350 122c5d916727d2f67a8b0b8347e15f8a 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.1E-8 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 ARZXY2_RS04350 122c5d916727d2f67a8b0b8347e15f8a 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.1E-8 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 ARZXY2_RS04350 122c5d916727d2f67a8b0b8347e15f8a 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.1E-8 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 Gene3D G3DSA:3.40.50.300 3 166 6.2E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 Pfam PF00425 chorismate binding enzyme 429 689 2.3E-85 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 Pfam PF04715 Anthranilate synthase component I, N terminal region 215 358 2.8E-9 T 09-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 SUPERFAMILY SSF52540 1 150 1.94E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 SUPERFAMILY SSF56322 211 392 1.57E-112 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 SUPERFAMILY SSF56322 419 698 1.57E-112 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 314 690 2.3E-99 T 09-03-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 Gene3D G3DSA:3.60.120.10 202 698 6.7E-131 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 PRINTS PR00095 Anthranilate synthase component I signature 626 640 6.9E-14 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 PRINTS PR00095 Anthranilate synthase component I signature 532 545 6.9E-14 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 PRINTS PR00095 Anthranilate synthase component I signature 546 559 6.9E-14 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS00495 c642c5eb8580eb98485b76dac2a8a698 703 PRINTS PR00095 Anthranilate synthase component I signature 641 655 6.9E-14 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 Gene3D G3DSA:1.10.10.10 115 175 2.0E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 Pfam PF04545 Sigma-70, region 4 125 174 1.5E-12 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 Gene3D G3DSA:1.10.1740.10 8 112 5.4E-11 T 09-03-2017 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 42 174 3.6E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 SUPERFAMILY SSF88659 105 176 5.98E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 SUPERFAMILY SSF88946 8 101 4.32E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15980 2946425479f698dda4df6f885ecc6a26 184 Pfam PF04542 Sigma-70 region 2 42 91 1.6E-5 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 Gene3D G3DSA:3.40.50.300 664 844 5.4E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 Pfam PF08455 Bacterial SNF2 helicase associated 367 627 3.8E-6 T 09-03-2017 IPR013663 Helicase, SWF/SNF/SWI type, bacterial ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 Pfam PF00271 Helicase conserved C-terminal domain 977 1080 3.0E-15 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 Gene3D G3DSA:3.40.50.300 968 1117 7.9E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 SUPERFAMILY SSF52540 656 889 2.41E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 Pfam PF00176 SNF2 family N-terminal domain 685 942 1.2E-54 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 SMART SM00490 1000 1080 5.4E-19 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 SUPERFAMILY SSF52540 890 1135 5.11E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00935 ffd1371a216457d98d65007383260116 1136 SMART SM00487 667 861 1.6E-19 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 SUPERFAMILY SSF55681 260 557 2.68E-91 T 09-03-2017 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Gene3D G3DSA:3.40.50.800 563 667 4.0E-29 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Pfam PF03129 Anticodon binding domain 573 660 8.5E-16 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 SUPERFAMILY SSF52954 561 666 2.57E-27 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 666 32.775 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 236 2.0E-11 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 SUPERFAMILY SSF55186 63 257 5.49E-55 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 SMART SM00863 179 236 9.8E-19 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Gene3D G3DSA:3.30.54.20 129 203 2.5E-16 T 09-03-2017 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Gene3D G3DSA:3.30.980.10 65 128 1.3E-37 T 09-03-2017 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Gene3D G3DSA:3.30.980.10 204 241 1.3E-37 T 09-03-2017 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 71 662 1.3E-195 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 PRINTS PR01047 Threonyl-tRNA synthetase signature 360 388 2.9E-52 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 PRINTS PR01047 Threonyl-tRNA synthetase signature 566 578 2.9E-52 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 PRINTS PR01047 Threonyl-tRNA synthetase signature 539 552 2.9E-52 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 PRINTS PR01047 Threonyl-tRNA synthetase signature 496 524 2.9E-52 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 PRINTS PR01047 Threonyl-tRNA synthetase signature 393 416 2.9E-52 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 355 561 1.6E-36 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07920 4c07d2dde8bd1ea98d88134eff8593c0 669 Gene3D G3DSA:3.30.930.10 259 562 3.2E-103 T 09-03-2017 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 Pfam PF02261 Aspartate decarboxylase 1 110 8.1E-48 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 Gene3D G3DSA:2.40.40.20 1 115 6.3E-52 T 09-03-2017 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 SUPERFAMILY SSF50692 1 112 9.11E-46 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 124 68.745 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 9.8E-50 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 1 110 2.0E-36 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 ARZXY2_RS00180 a3a5a4dd937f049fa2049b0eb8ce21f9 139 PIRSF PIRSF006246 1 126 2.5E-48 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 ARZXY2_RS18775 ec3bde71b7697619f46ff35d97c1237d 112 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 110 2.8E-44 T 09-03-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 ARZXY2_RS18775 ec3bde71b7697619f46ff35d97c1237d 112 SUPERFAMILY SSF103481 10 108 1.57E-8 T 09-03-2017 ARZXY2_RS18775 ec3bde71b7697619f46ff35d97c1237d 112 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 22.152 T 09-03-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 SMART SM01208 207 285 7.3E-24 T 09-03-2017 IPR011098 G5 domain ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 Pfam PF07501 G5 domain 211 284 2.9E-19 T 09-03-2017 IPR011098 G5 domain ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 Pfam PF03990 Domain of unknown function (DUF348) 40 80 4.2E-11 T 09-03-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 Pfam PF03990 Domain of unknown function (DUF348) 153 191 1.6E-10 T 09-03-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 Pfam PF06737 Transglycosylase-like domain 306 380 3.8E-31 T 09-03-2017 IPR010618 Transglycosylase-like ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 SUPERFAMILY SSF53955 306 381 2.72E-28 T 09-03-2017 IPR023346 Lysozyme-like domain ARZXY2_RS12810 b81f986f1e371b5e4243f1a762dcd7c4 383 Gene3D G3DSA:1.10.530.10 290 380 4.4E-35 T 09-03-2017 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 SUPERFAMILY SSF81442 23 535 9.94E-177 T 09-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 09-03-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 Gene3D G3DSA:1.20.210.10 20 551 2.9E-195 T 09-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 1.0E-150 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 1.8E-101 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08385 2220ba7f27a263f2a6d24d2ec6af2827 573 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 27 532 2.6E-213 T 09-03-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 75 292 4.2E-42 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SMART SM01217 751 818 3.8E-22 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Gene3D G3DSA:3.40.50.1700 316 397 1.1E-70 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Gene3D G3DSA:3.40.50.1700 559 717 1.1E-70 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 PRINTS PR00133 Glycosyl hydrolase family 3 signature 50 66 3.2E-26 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 PRINTS PR00133 Glycosyl hydrolase family 3 signature 79 98 3.2E-26 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 PRINTS PR00133 Glycosyl hydrolase family 3 signature 125 141 3.2E-26 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 PRINTS PR00133 Glycosyl hydrolase family 3 signature 225 243 3.2E-26 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 PRINTS PR00133 Glycosyl hydrolase family 3 signature 156 172 3.2E-26 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SUPERFAMILY SSF52279 704 717 1.7E-52 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SUPERFAMILY SSF52279 328 397 1.7E-52 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SUPERFAMILY SSF52279 559 670 1.7E-52 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 328 691 7.0E-60 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Pfam PF14310 Fibronectin type III-like domain 751 817 4.2E-17 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 Gene3D G3DSA:3.20.20.300 15 302 4.6E-85 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SUPERFAMILY SSF56988 448 604 2.48E-6 T 09-03-2017 ARZXY2_RS15825 9925db03ad1d0ff6b6e7243f1d9d8c04 830 SUPERFAMILY SSF51445 15 308 5.69E-77 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 Pfam PF00106 short chain dehydrogenase 10 190 4.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 Gene3D G3DSA:3.40.50.720 7 239 1.7E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07620 d14d284bac66e81d0059f71b6d82f5b1 255 SUPERFAMILY SSF51735 8 230 2.32E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04045 a76eef8b041ec5d4a720aa65b5776536 411 SUPERFAMILY SSF103473 27 405 1.24E-34 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS04045 a76eef8b041ec5d4a720aa65b5776536 411 Pfam PF07690 Major Facilitator Superfamily 33 366 1.1E-21 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS04045 a76eef8b041ec5d4a720aa65b5776536 411 Gene3D G3DSA:1.20.1250.20 26 201 2.7E-21 T 09-03-2017 ARZXY2_RS09005 1480646bfd213acf18ddeed23120853d 273 Gene3D G3DSA:1.10.10.10 32 132 2.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09005 1480646bfd213acf18ddeed23120853d 273 SUPERFAMILY SSF46785 30 225 1.13E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09005 1480646bfd213acf18ddeed23120853d 273 Pfam PF12840 Helix-turn-helix domain 30 80 8.7E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 SMART SM00100 11 129 8.6E-29 T 09-03-2017 IPR000595 Cyclic nucleotide-binding domain ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 SMART SM00419 168 216 7.0E-13 T 09-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 79 96 - T 09-03-2017 IPR018488 Cyclic nucleotide-binding, conserved site ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 SUPERFAMILY SSF51206 5 143 1.44E-39 T 09-03-2017 IPR018490 Cyclic nucleotide-binding-like ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 SUPERFAMILY SSF46785 146 223 7.55E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 Gene3D G3DSA:2.60.120.10 3 143 5.6E-41 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 PRINTS PR00103 cAMP-dependent protein kinase signature 32 46 4.3E-6 T 09-03-2017 ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 PRINTS PR00103 cAMP-dependent protein kinase signature 77 86 4.3E-6 T 09-03-2017 ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 PRINTS PR00103 cAMP-dependent protein kinase signature 89 100 4.3E-6 T 09-03-2017 ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 Pfam PF13545 Crp-like helix-turn-helix domain 149 222 6.7E-18 T 09-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 Pfam PF00027 Cyclic nucleotide-binding domain 30 116 7.2E-26 T 09-03-2017 IPR000595 Cyclic nucleotide-binding domain ARZXY2_RS01730 67efa4e87f2a4c3baed3365e45e5fba4 225 Gene3D G3DSA:1.10.10.10 146 223 8.4E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS23285 9b850e192e63652ddefc7955b97b34a7 108 SUPERFAMILY SSF161098 2 108 1.02E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS23285 9b850e192e63652ddefc7955b97b34a7 108 Gene3D G3DSA:1.10.3720.10 2 108 6.8E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS23285 9b850e192e63652ddefc7955b97b34a7 108 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 2 103 1.0E-13 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS20270 7dc186ce94d6dffae998deec0ef5dbaf 157 SUPERFAMILY SSF89562 5 155 6.67E-45 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS20270 7dc186ce94d6dffae998deec0ef5dbaf 157 Gene3D G3DSA:3.50.30.40 4 155 1.1E-46 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS20270 7dc186ce94d6dffae998deec0ef5dbaf 157 TIGRFAM TIGR01935 NOT-MenG: RraA family 7 155 7.1E-59 T 09-03-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 ARZXY2_RS20270 7dc186ce94d6dffae998deec0ef5dbaf 157 Pfam PF03737 Demethylmenaquinone methyltransferase 7 155 3.5E-42 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 5.7E-23 T 09-03-2017 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 271 286 5.7E-23 T 09-03-2017 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.7E-23 T 09-03-2017 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 302 5.7E-23 T 09-03-2017 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 Pfam PF01494 FAD binding domain 6 335 5.8E-43 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 Gene3D G3DSA:3.50.50.60 259 332 1.8E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 Gene3D G3DSA:3.50.50.60 5 178 1.8E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 SUPERFAMILY SSF51905 5 173 7.21E-56 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08555 fa9667636d2db3996aafde93ab78f605 379 SUPERFAMILY SSF51905 258 370 7.21E-56 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 SUPERFAMILY SSF52540 113 362 8.81E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 Pfam PF01883 Domain of unknown function DUF59 7 78 9.4E-17 T 09-03-2017 IPR002744 Domain of unknown function DUF59 ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 Hamap MF_02040 Iron-sulfur cluster carrier protein. 107 359 32.567 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 SUPERFAMILY SSF117916 4 96 6.87E-23 T 09-03-2017 ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 Gene3D G3DSA:3.40.50.300 104 357 1.6E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04355 2b8157edef987bfa2eca3b91bbf43016 375 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 113 358 5.7E-85 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.30.1490.20 687 743 1.2E-25 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF52440 1 127 2.59E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF52335 957 1091 1.3E-31 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.5E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 9.9E-68 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 874 1.7E-34 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF56059 673 947 1.45E-93 T 09-03-2017 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.30.470.20 744 948 3.1E-64 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.30.470.20 200 399 2.3E-76 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 542 1.9E-38 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.40.50.1380 953 1092 2.5E-39 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF52440 554 673 1.42E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Pfam PF02142 MGS-like domain 975 1061 4.7E-20 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF56059 128 400 6.54E-105 T 09-03-2017 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SMART SM01096 421 542 5.9E-63 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.40.50.20 534 661 2.2E-55 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.30.1490.20 143 199 3.4E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SUPERFAMILY SSF48108 395 548 2.88E-46 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 SMART SM00851 970 1061 9.1E-26 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1072 0.0 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 708 722 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:1.10.1030.10 400 533 1.3E-46 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 837 844 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Gene3D G3DSA:3.40.50.20 4 108 5.7E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS08140 f73018b52f016939de5653ea333c5ad5 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1082 12.849 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 Gene3D G3DSA:3.10.25.10 205 305 1.2E-26 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 Pfam PF02911 Formyl transferase, C-terminal domain 201 297 2.7E-22 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 SUPERFAMILY SSF53328 1 195 1.44E-51 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 SUPERFAMILY SSF50486 203 300 7.69E-26 T 09-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 Gene3D G3DSA:3.40.50.170 1 202 9.1E-54 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 303 2.1E-66 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 300 31.323 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 ARZXY2_RS10355 5a281925ade83742beba789955f46931 306 Pfam PF00551 Formyl transferase 3 173 1.9E-30 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 8.7E-50 T 09-03-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 PIRSF PIRSF001223 1 100 2.5E-51 T 09-03-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 Gene3D G3DSA:3.30.280.10 1 100 5.8E-50 T 09-03-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-43 T 09-03-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.663 T 09-03-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 Pfam PF00547 Urease, gamma subunit 1 99 1.7E-47 T 09-03-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17590 11345b49a77494a86d72253f91ced8ba 100 SUPERFAMILY SSF54111 1 100 3.66E-47 T 09-03-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 SUPERFAMILY SSF52172 3 178 2.56E-39 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 SMART SM00862 148 224 3.6E-24 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 Gene3D G3DSA:1.10.10.10 127 225 7.8E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 Gene3D G3DSA:3.40.50.2300 3 118 8.1E-35 T 09-03-2017 ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.1E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS17775 65981ce2f84231790a18d72dfecb2006 226 SMART SM00448 2 112 1.3E-42 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:3.30.450.20 346 455 9.2E-25 T 09-03-2017 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF52172 719 844 7.12E-26 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF08448 PAS fold 351 459 1.5E-15 T 09-03-2017 IPR013656 PAS fold-4 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00387 589 705 2.4E-38 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00073 1034 1135 4.0E-6 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:3.40.50.2300 868 986 4.2E-42 T 09-03-2017 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF52172 868 985 5.69E-36 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF01627 Hpt domain 1046 1128 6.0E-12 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF00072 Response regulator receiver domain 724 839 2.2E-16 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF00072 Response regulator receiver domain 870 980 7.0E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF47384 463 543 9.61E-21 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:3.40.50.2300 721 847 6.1E-27 T 09-03-2017 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:1.10.287.130 471 538 9.8E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00448 722 840 1.8E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00448 867 981 6.8E-34 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00388 477 542 1.2E-23 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 589 704 7.1E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Pfam PF00512 His Kinase A (phospho-acceptor) domain 478 542 1.8E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 702 9.0E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 644 9.0E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 PRINTS PR00344 Bacterial sensor protein C-terminal signature 648 658 9.0E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 683 9.0E-15 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SMART SM00091 344 410 3.1E-7 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF55785 355 464 8.54E-28 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 344 464 2.6E-24 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF55874 531 702 1.17E-45 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:1.20.120.160 1019 1132 9.6E-20 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 Gene3D G3DSA:3.30.565.10 543 704 5.0E-46 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF47226 964 977 4.97E-17 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS02370 7d2b48df2dc5fa102987c5715b0ab342 1139 SUPERFAMILY SSF47226 1024 1106 4.97E-17 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 Pfam PF03459 TOBE domain 65 126 2.0E-8 T 09-03-2017 IPR005116 Transport-associated OB, type 1 ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 38 3.0E-8 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 SUPERFAMILY SSF50331 10 127 7.78E-17 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 Gene3D G3DSA:1.10.1660.10 5 37 6.2E-5 T 09-03-2017 ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 Gene3D G3DSA:2.40.50.100 65 127 2.1E-20 T 09-03-2017 ARZXY2_RS01065 bf6d26bcd0c492b656dcebd7a0a5bd5d 136 Pfam PF00376 MerR family regulatory protein 5 38 3.9E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 PRINTS PR00084 Mannitol dehydrogenase signature 156 169 1.4E-15 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 PRINTS PR00084 Mannitol dehydrogenase signature 195 208 1.4E-15 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 PRINTS PR00084 Mannitol dehydrogenase signature 225 240 1.4E-15 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 PRINTS PR00084 Mannitol dehydrogenase signature 19 29 1.4E-15 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 SUPERFAMILY SSF51735 11 259 7.09E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 Gene3D G3DSA:1.10.1040.10 259 415 1.2E-40 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 195 207 - T 09-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 194 416 1.8E-56 T 09-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 SUPERFAMILY SSF48179 260 434 2.45E-37 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 Gene3D G3DSA:3.40.50.720 12 258 1.3E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16215 26ab4708d0afa0a54460db191f31c139 461 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 18 165 6.4E-23 T 09-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 ARZXY2_RS19630 adaf9167f81dba93ff129484e4341419 919 SUPERFAMILY SSF49899 692 898 1.5E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS19630 adaf9167f81dba93ff129484e4341419 919 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 739 883 1.2E-10 T 09-03-2017 ARZXY2_RS19630 adaf9167f81dba93ff129484e4341419 919 Gene3D G3DSA:2.60.120.200 714 896 1.1E-12 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 09-03-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.9E-60 T 09-03-2017 IPR023798 Ribosomal protein S7 domain ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 SUPERFAMILY SSF47973 1 149 9.03E-58 T 09-03-2017 IPR023798 Ribosomal protein S7 domain ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.846 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 PIRSF PIRSF002122 4 156 3.5E-55 T 09-03-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.1E-65 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03465 016e2383cc8b28bd1f83ae52e125e916 156 Gene3D G3DSA:1.10.455.10 8 156 1.4E-61 T 09-03-2017 IPR023798 Ribosomal protein S7 domain ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 PIRSF PIRSF029271 10 308 2.5E-150 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 Pfam PF01680 SOR/SNZ family 21 226 3.4E-107 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 18 308 52.892 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 Gene3D G3DSA:3.20.20.70 38 174 1.3E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 Gene3D G3DSA:3.20.20.70 206 292 1.3E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 SUPERFAMILY SSF51366 32 281 2.78E-62 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 23 308 1.0E-144 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07935 9921d0b24af62abef417dddc11a202b9 308 ProSitePatterns PS01235 PdxS/SNZ family signature. 219 237 - T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 SUPERFAMILY SSF52518 19 408 2.36E-60 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 Gene3D G3DSA:3.40.50.970 18 408 5.9E-89 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 SUPERFAMILY SSF52922 653 797 1.26E-20 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 PIRSF PIRSF000156 2 798 3.4E-61 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 SMART SM00861 433 637 7.1E-5 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 Gene3D G3DSA:3.40.50.920 658 797 3.4E-31 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 SUPERFAMILY SSF52518 428 637 3.77E-46 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 58 254 7.6E-8 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS09655 988af523f56949a633f54ea0dd24d369 798 Gene3D G3DSA:3.40.50.970 428 645 6.2E-67 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 48 153 3.3E-6 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 PIRSF PIRSF000168 13 699 4.8E-172 T 09-03-2017 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0050660|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Pfam PF01756 Acyl-CoA oxidase 529 663 1.0E-18 T 09-03-2017 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 303 464 1.0E-9 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Gene3D G3DSA:2.40.110.10 158 289 8.5E-42 T 09-03-2017 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 159 269 1.0E-12 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Gene3D G3DSA:1.10.540.10 47 156 8.2E-7 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 SUPERFAMILY SSF56645 44 282 3.4E-52 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 SUPERFAMILY SSF47203 299 482 4.99E-50 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Gene3D G3DSA:1.20.140.10 523 652 1.7E-32 T 09-03-2017 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 SUPERFAMILY SSF47203 524 663 1.46E-33 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS08835 70d3e836c1d9daf29717aa55e30abf11 703 Gene3D G3DSA:1.20.140.10 310 472 4.1E-52 T 09-03-2017 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 Gene3D G3DSA:3.30.2130.10 1 128 4.3E-48 T 09-03-2017 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 Pfam PF10000 ACT domain 2 68 2.5E-21 T 09-03-2017 IPR018717 Domain of unknown function DUF2241 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 Gene3D G3DSA:3.40.630.30 130 268 4.9E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 SUPERFAMILY SSF55021 69 127 4.35E-17 T 09-03-2017 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 Pfam PF13508 Acetyltransferase (GNAT) domain 187 264 5.8E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 SUPERFAMILY SSF55021 3 65 7.32E-14 T 09-03-2017 ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 Pfam PF13840 ACT domain 69 125 1.4E-11 T 09-03-2017 IPR027795 GATS-like ACT domain ARZXY2_RS13095 ec1d2969c8c1e9504705a4f39b1f4623 306 SUPERFAMILY SSF55729 131 268 4.03E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09320 b3a38da9d20c8d39b3efb49347ed11e5 265 Pfam PF02585 GlcNAc-PI de-N-acetylase 18 189 1.1E-7 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS09320 b3a38da9d20c8d39b3efb49347ed11e5 265 Gene3D G3DSA:3.40.50.10320 18 111 2.3E-7 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS09320 b3a38da9d20c8d39b3efb49347ed11e5 265 Gene3D G3DSA:3.40.50.10320 148 196 2.3E-7 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS09320 b3a38da9d20c8d39b3efb49347ed11e5 265 SUPERFAMILY SSF102588 148 259 2.88E-15 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS09320 b3a38da9d20c8d39b3efb49347ed11e5 265 SUPERFAMILY SSF102588 17 111 2.88E-15 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS07490 e0dc5c800165e56a72af724647581898 197 SMART SM00479 1 167 2.4E-10 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS07490 e0dc5c800165e56a72af724647581898 197 Gene3D G3DSA:3.30.420.10 1 166 1.5E-56 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07490 e0dc5c800165e56a72af724647581898 197 Pfam PF00929 Exonuclease 1 157 4.5E-20 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS07490 e0dc5c800165e56a72af724647581898 197 SUPERFAMILY SSF53098 1 166 1.26E-31 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS11270 290eb972229cfb1483069d4499022f8d 363 Pfam PF04055 Radical SAM superfamily 77 251 3.0E-11 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS11270 290eb972229cfb1483069d4499022f8d 363 SMART SM00729 73 300 5.3E-4 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS11270 290eb972229cfb1483069d4499022f8d 363 SUPERFAMILY SSF102114 73 287 3.53E-9 T 09-03-2017 ARZXY2_RS11270 290eb972229cfb1483069d4499022f8d 363 Gene3D G3DSA:3.20.20.70 76 336 1.3E-8 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Gene3D G3DSA:1.20.120.140 2 89 1.8E-34 T 09-03-2017 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.2 T 09-03-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 SMART SM00962 100 304 5.7E-106 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 436 2.6E-173 T 09-03-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Pfam PF00448 SRP54-type protein, GTPase domain 100 303 1.2E-67 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 SMART SM00382 99 309 1.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 SUPERFAMILY SSF47446 336 437 6.05E-34 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 277 290 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 SUPERFAMILY SSF52540 42 363 4.78E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.0E-22 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Pfam PF02978 Signal peptide binding domain 337 434 7.1E-31 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Gene3D G3DSA:3.40.50.300 95 305 4.9E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 Gene3D G3DSA:1.10.260.30 337 438 5.7E-37 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 ARZXY2_RS06975 ae6c77ddb27d5d26e207e8337c0829fe 525 SMART SM00963 1 86 5.3E-35 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 Gene3D G3DSA:3.40.50.300 663 772 7.4E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 Gene3D G3DSA:3.40.50.300 842 896 7.4E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SUPERFAMILY SSF52540 745 903 4.96E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SUPERFAMILY SSF52540 645 710 4.96E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SMART SM00382 545 777 1.4E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SUPERFAMILY SSF55464 137 366 1.88E-76 T 09-03-2017 ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SUPERFAMILY SSF55464 3 95 1.88E-76 T 09-03-2017 ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 Gene3D G3DSA:3.40.50.300 530 662 9.0E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 Pfam PF08751 TrwC relaxase 12 364 3.0E-99 T 09-03-2017 IPR014862 TrwC relaxase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 SUPERFAMILY SSF52540 525 675 3.45E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19460 72f8d8d40d39686247fcb8a56547bb57 1162 Pfam PF13604 AAA domain 529 727 2.4E-56 T 09-03-2017 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 PIRSF PIRSF001430 17 295 2.8E-64 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 SUPERFAMILY SSF55120 17 286 1.04E-65 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 Gene3D G3DSA:3.30.70.660 140 276 2.5E-32 T 09-03-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 17 278 29.002 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 Gene3D G3DSA:3.30.70.580 18 138 2.8E-27 T 09-03-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS03680 f8fe35fbc5513e0aa72017fb73a0eac0 296 Pfam PF01416 tRNA pseudouridine synthase 179 279 1.2E-18 T 09-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS00385 5bc15bb9f84977fdb3ec3ae828390e03 127 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 18 104 4.2E-24 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 ARZXY2_RS00385 5bc15bb9f84977fdb3ec3ae828390e03 127 Pfam PF03334 Na+/H+ antiporter subunit 19 98 1.7E-26 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 750 824 3.0E-15 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 SMART SM00640 51 824 2.4E-157 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 51 64 - T 09-03-2017 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Gene3D G3DSA:2.120.10.10 97 239 1.1E-9 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Gene3D G3DSA:2.120.10.10 279 322 1.1E-9 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 SUPERFAMILY SSF49899 704 863 1.5E-31 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Gene3D G3DSA:2.60.120.560 696 863 6.1E-38 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 SUPERFAMILY SSF75005 43 310 3.77E-102 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 SUPERFAMILY SSF75005 635 702 3.77E-102 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 51 300 1.4E-75 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS19855 768fdae541eb13a8a8fbc9dcefd14896 865 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 627 701 3.2E-17 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 Pfam PF11762 L-arabinose isomerase C-terminal domain 370 483 1.5E-46 T 09-03-2017 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 PIRSF PIRSF001478 9 507 1.5E-231 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 SUPERFAMILY SSF50443 337 505 5.75E-65 T 09-03-2017 IPR004216 L-fucose/L-arabinose isomerase, C-terminal ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 Pfam PF02610 L-arabinose isomerase 13 366 2.3E-172 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 SUPERFAMILY SSF53743 12 335 6.67E-118 T 09-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 Hamap MF_00519 L-arabinose isomerase [araA]. 9 484 63.658 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ARZXY2_RS00225 f5ddf62ee18c84824aa599ca35e3c5bb 509 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 11 312 3.0E-149 T 09-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 ProSitePatterns PS00164 Enolase signature. 332 345 - T 09-03-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 SMART SM01192 139 423 8.6E-224 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 Pfam PF03952 Enolase, N-terminal domain 4 134 7.8E-62 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 161 174 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 332 346 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 107 123 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 361 378 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 309 320 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PRINTS PR00148 Enolase signature 37 51 1.2E-47 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 PIRSF PIRSF001400 1 422 8.6E-195 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 Gene3D G3DSA:3.30.390.10 4 125 7.8E-58 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 2.0E-209 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 Gene3D G3DSA:3.20.20.120 128 421 1.0E-135 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 420 6.7E-134 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 SUPERFAMILY SSF51604 138 422 1.7E-130 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 SMART SM01193 4 134 4.4E-97 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 SUPERFAMILY SSF54826 3 138 8.99E-59 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS13125 7b22980e83585ff3f789ab457f8492b2 426 Hamap MF_00318 Enolase [eno]. 2 409 46.086 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS19875 1e44899f1a4c116f1aa0da89483ecff7 181 Gene3D G3DSA:3.40.50.850 3 179 7.7E-41 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS19875 1e44899f1a4c116f1aa0da89483ecff7 181 SUPERFAMILY SSF52499 3 180 8.37E-38 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS19875 1e44899f1a4c116f1aa0da89483ecff7 181 Pfam PF00857 Isochorismatase family 3 163 1.2E-27 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 33 448 4.2E-180 T 09-03-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 SUPERFAMILY SSF53383 41 447 2.42E-125 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 Gene3D G3DSA:3.90.1150.10 330 449 5.1E-42 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 Pfam PF00202 Aminotransferase class-III 47 446 3.0E-125 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS02950 c471c1921f9480b130ad8eba2125bb16 451 Gene3D G3DSA:3.40.640.10 83 329 8.3E-84 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 Gene3D G3DSA:3.90.76.10 73 219 2.5E-34 T 09-03-2017 ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 105 454 9.2E-73 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 PIRSF PIRSF002741 17 536 2.5E-72 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 Gene3D G3DSA:3.10.105.10 295 509 3.9E-39 T 09-03-2017 ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 110 132 - T 09-03-2017 IPR023765 Solute-binding protein family 5, conserved site ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 15 37 3.7E-6 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal ARZXY2_RS15135 71ea988b277b68dcada58f45bdf709ab 540 SUPERFAMILY SSF53850 70 537 1.15E-98 T 09-03-2017 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 Gene3D G3DSA:3.30.379.10 7 142 1.4E-28 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 Gene3D G3DSA:3.20.20.80 143 507 7.2E-96 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 334 473 5.4E-20 T 09-03-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 145 328 1.6E-52 T 09-03-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 SUPERFAMILY SSF51445 145 486 2.22E-94 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 311 324 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 437 453 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 90 110 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 289 307 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 241 258 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 PRINTS PR00738 Glycosyl hydrolase family 20 signature 455 472 5.1E-28 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 SUPERFAMILY SSF55545 7 144 1.94E-22 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS14775 d080502c8b423e41570c43c858d4ed16 530 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 7 142 1.4E-20 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 195 1.2E-25 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 262 350 1.6E-25 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 13 352 59.125 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 14 350 2.5E-97 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 SUPERFAMILY SSF53901 12 351 2.45E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 Gene3D G3DSA:3.40.47.10 13 182 1.2E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS07330 048354fdb0ce64754569bc1b2bc261b1 353 Gene3D G3DSA:3.40.47.10 224 350 1.6E-41 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 4.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 4.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.0E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 SUPERFAMILY SSF46689 10 83 5.49E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 SUPERFAMILY SSF48498 80 192 1.02E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 Gene3D G3DSA:1.10.10.60 10 58 3.3E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS16980 9fac4f1370ecb463f19beb08dc99fea6 196 Gene3D G3DSA:1.10.357.10 59 194 1.5E-33 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS22790 173e02bd6068d009069048152b41d787 148 Pfam PF00296 Luciferase-like monooxygenase 1 146 9.6E-14 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS22790 173e02bd6068d009069048152b41d787 148 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 1 146 6.6E-61 T 09-03-2017 IPR019949 Luciferase family oxidoreductase, group 1 ARZXY2_RS22790 173e02bd6068d009069048152b41d787 148 Gene3D G3DSA:3.20.20.30 1 146 1.5E-37 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS22790 173e02bd6068d009069048152b41d787 148 SUPERFAMILY SSF51679 8 147 8.77E-44 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 Pfam PF01632 Ribosomal protein L35 2 62 2.8E-24 T 09-03-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.556 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.9E-15 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.9E-15 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.9E-15 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 09-03-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.4E-25 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11295 b716dffbf289c3ebcb622b121e49b066 64 SUPERFAMILY SSF143034 2 63 3.53E-22 T 09-03-2017 ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 PRINTS PR01438 Universal stress protein signature 116 138 8.3E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 PRINTS PR01438 Universal stress protein signature 99 111 8.3E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 PRINTS PR01438 Universal stress protein signature 2 20 8.3E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 Gene3D G3DSA:3.40.50.620 5 137 4.6E-29 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 SUPERFAMILY SSF52402 5 138 1.47E-24 T 09-03-2017 ARZXY2_RS17495 278ebe02b1aa73d77a4f5f8ba35ff9f4 143 Pfam PF00582 Universal stress protein family 1 137 1.5E-25 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 31 96 1.6E-12 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 SUPERFAMILY SSF50615 26 98 2.94E-22 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 SUPERFAMILY SSF52540 100 382 4.72E-95 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 507 5.6E-47 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Gene3D G3DSA:2.40.30.20 5 97 1.9E-26 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 7.6E-68 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 SUPERFAMILY SSF47917 385 511 4.71E-46 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.071 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 511 4.6E-236 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Gene3D G3DSA:3.40.50.300 98 383 4.5E-110 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05250 3ec1ae6ec801e7000357169d4a408f32 545 Gene3D G3DSA:1.20.150.20 385 511 2.0E-52 T 09-03-2017 ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 Gene3D G3DSA:1.20.1250.20 2 198 3.3E-24 T 09-03-2017 ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 Gene3D G3DSA:1.20.1250.20 220 409 3.8E-17 T 09-03-2017 ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 ProSitePatterns PS00216 Sugar transport proteins signature 1. 275 291 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 Pfam PF07690 Major Facilitator Superfamily 23 358 1.2E-29 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 SUPERFAMILY SSF103473 1 410 2.09E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16935 aabbddb572d5a67d50285c4e15796434 412 ProSitePatterns PS00217 Sugar transport proteins signature 2. 102 127 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 SUPERFAMILY SSF52540 4 221 1.14E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 SMART SM00382 29 225 2.1E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 SUPERFAMILY SSF52540 265 471 4.67E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 Gene3D G3DSA:3.40.50.300 265 472 3.0E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 Gene3D G3DSA:3.40.50.300 4 220 4.6E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 Pfam PF00005 ABC transporter 266 416 3.5E-15 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08910 18f03f74cf95bb42d3fc6e945c079995 510 Pfam PF00005 ABC transporter 20 164 1.2E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 Pfam PF08386 TAP-like protein 197 242 3.3E-7 T 09-03-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 3.5E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 3.5E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 3.5E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 3.5E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 Gene3D G3DSA:3.40.50.1820 5 253 7.9E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 SUPERFAMILY SSF53474 8 247 3.46E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS01440 0c1b1092dc7feff233fe8400ca67025c 259 Pfam PF00561 alpha/beta hydrolase fold 22 182 1.6E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 Pfam PF00248 Aldo/keto reductase family 10 294 1.8E-56 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 PRINTS PR00069 Aldo-keto reductase signature 194 223 2.7E-8 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 PRINTS PR00069 Aldo-keto reductase signature 110 128 2.7E-8 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 PRINTS PR00069 Aldo-keto reductase signature 242 266 2.7E-8 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 SUPERFAMILY SSF51430 9 307 6.94E-69 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS03210 a3320aa74139a985680411c1ffa00aa8 317 Gene3D G3DSA:3.20.20.100 9 305 9.0E-66 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS00605 35c39b281b405b6ffc5c83b7c204a209 152 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 28 74 3.8E-15 T 09-03-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ARZXY2_RS00605 35c39b281b405b6ffc5c83b7c204a209 152 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 91 1.0E-12 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ARZXY2_RS00605 35c39b281b405b6ffc5c83b7c204a209 152 SUPERFAMILY SSF69118 16 144 1.44E-36 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS00605 35c39b281b405b6ffc5c83b7c204a209 152 Gene3D G3DSA:1.20.1290.10 14 145 2.5E-43 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 Gene3D G3DSA:3.40.630.30 81 161 3.0E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 Pfam PF13527 Acetyltransferase (GNAT) domain 82 159 6.6E-15 T 09-03-2017 ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 SUPERFAMILY SSF55729 48 329 5.99E-42 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 SUPERFAMILY SSF55718 330 436 7.06E-19 T 09-03-2017 IPR003033 SCP2 sterol-binding domain ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 Gene3D G3DSA:3.40.630.30 172 314 1.4E-29 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 Pfam PF13530 Sterol carrier protein domain 208 432 1.9E-46 T 09-03-2017 IPR025559 Enhanced intracellular survival protein domain ARZXY2_RS09180 df286077073f013c8535c6180b27d210 436 Gene3D G3DSA:3.30.1050.10 331 425 3.2E-19 T 09-03-2017 IPR003033 SCP2 sterol-binding domain ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 SUPERFAMILY SSF51344 4 84 6.54E-21 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 87 3.0E-21 T 09-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 93 11.52 T 09-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 8.7E-24 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 87 1.0E-23 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05265 9ce70e9bd57173fcf9c5342e45a20de0 94 Gene3D G3DSA:2.60.15.10 1 86 1.2E-23 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS02430 f38315db00b1d70c91c4cc47a47c1c56 213 SUPERFAMILY SSF51306 63 119 1.1E-5 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS02430 f38315db00b1d70c91c4cc47a47c1c56 213 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 45 167 7.9E-23 T 09-03-2017 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 ARZXY2_RS02430 f38315db00b1d70c91c4cc47a47c1c56 213 Gene3D G3DSA:2.10.109.10 63 154 3.8E-5 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS02430 f38315db00b1d70c91c4cc47a47c1c56 213 Pfam PF00717 Peptidase S24-like 68 118 8.6E-5 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS09435 5ce0946beb0314128ca83197452f9e8b 290 Pfam PF13622 Thioesterase-like superfamily 39 286 5.5E-53 T 09-03-2017 ARZXY2_RS09435 5ce0946beb0314128ca83197452f9e8b 290 Gene3D G3DSA:3.10.129.10 133 288 1.6E-47 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09435 5ce0946beb0314128ca83197452f9e8b 290 SUPERFAMILY SSF54637 124 287 9.9E-46 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09435 5ce0946beb0314128ca83197452f9e8b 290 Gene3D G3DSA:3.10.129.10 10 121 1.2E-32 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09435 5ce0946beb0314128ca83197452f9e8b 290 SUPERFAMILY SSF54637 11 121 8.4E-31 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS08745 f0fa020d33f860d87638062312113222 301 Pfam PF11316 Putative rhamnosyl transferase 4 212 1.1E-51 T 09-03-2017 IPR021466 Putative rhamnosyl transferase ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 277 32.459 T 09-03-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 266 7.4E-34 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 267 1.4E-80 T 09-03-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 Gene3D G3DSA:3.20.20.70 7 270 9.5E-64 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 SUPERFAMILY SSF51366 5 271 9.85E-63 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS08145 6a98afb840ea5dc9005e77fab597f7f1 277 SMART SM00934 18 267 1.1E-26 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 SUPERFAMILY SSF52467 173 350 1.47E-33 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Gene3D G3DSA:3.40.50.970 370 555 3.3E-40 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Gene3D G3DSA:3.40.50.970 17 192 3.8E-48 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 SUPERFAMILY SSF52518 17 192 5.89E-41 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 553 2.2E-29 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 19 188 4.5E-47 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 SUPERFAMILY SSF52518 388 555 2.14E-37 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Gene3D G3DSA:3.40.50.1220 204 350 2.4E-38 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS13980 1935a1500b4806fc9289a6551cb43d89 567 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 340 2.7E-27 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 5 200 4.0E-96 T 09-03-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 Gene3D G3DSA:3.40.50.300 4 195 2.2E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 PIRSF PIRSF005624 2 202 3.4E-47 T 09-03-2017 ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 SUPERFAMILY SSF52540 3 196 2.34E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 Hamap MF_01389 Urease accessory protein UreG [ureG]. 3 201 44.335 T 09-03-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 ARZXY2_RS17565 e99249bce0de3a0f3995a6376f178278 205 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 176 6.0E-38 T 09-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 SUPERFAMILY SSF56214 1 114 3.66E-24 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 Gene3D G3DSA:3.90.470.20 1 114 2.0E-34 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 115 18.839 T 09-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 13 78 1.0E-24 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 113 1.1E-19 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 ARZXY2_RS03760 b15a7ec26ce6c8e8afb741d1a7f2e96f 115 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 99 2.0E-11 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.5E-85 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 Gene3D G3DSA:3.40.50.140 115 169 1.7E-5 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 Pfam PF02132 RecR protein 39 77 6.1E-17 T 09-03-2017 IPR023628 Recombination protein RecR, C4-type zinc finger ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 09-03-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 106.223 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 Pfam PF13662 Toprim domain 79 170 1.2E-25 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 Gene3D G3DSA:3.90.79.10 64 112 7.6E-4 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 SMART SM00493 79 164 3.0E-14 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS15805 e565209556cf7be7bfd96a3a7b45c991 199 SUPERFAMILY SSF111304 2 196 1.31E-74 T 09-03-2017 IPR023627 Recombination protein RecR ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 Gene3D G3DSA:1.10.10.10 3 73 2.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 Gene3D G3DSA:3.30.450.40 74 234 8.3E-40 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 SUPERFAMILY SSF55781 62 234 1.7E-34 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 Pfam PF09339 IclR helix-turn-helix domain 10 57 2.8E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 SMART SM00346 7 93 2.0E-19 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 SUPERFAMILY SSF46785 7 75 5.45E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05745 94207926c3a50ef5ad724286470d83ed 239 Pfam PF01614 Bacterial transcriptional regulator 125 230 1.7E-16 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 Gene3D G3DSA:3.30.160.20 63 126 4.7E-30 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 Pfam PF03719 Ribosomal protein S5, C-terminal domain 141 211 1.1E-27 T 09-03-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 ProSitePatterns PS00585 Ribosomal protein S5 signature. 82 114 - T 09-03-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 Gene3D G3DSA:3.30.230.10 131 212 8.0E-32 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 SUPERFAMILY SSF54211 133 212 2.25E-24 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 SUPERFAMILY SSF54768 62 130 8.16E-23 T 09-03-2017 ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 Pfam PF00333 Ribosomal protein S5, N-terminal domain 66 129 5.0E-28 T 09-03-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 63 216 4.0E-67 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03575 912b16c14f256239c0e5630eb92147ab 234 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 28 217 34.383 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 SUPERFAMILY SSF46785 23 123 1.17E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 4.8E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 4.8E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 Gene3D G3DSA:1.10.10.10 24 96 8.8E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 Gene3D G3DSA:1.20.120.530 108 241 2.9E-30 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 SUPERFAMILY SSF48008 108 232 2.2E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 92 1.2E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 SMART SM00345 33 92 9.1E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 Pfam PF07729 FCD domain 110 230 1.0E-26 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS20465 ed268f770078fa6495504ecbd166b3de 242 SMART SM00895 110 231 8.2E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS06535 0dea9cb19a1ebef9ab79e60b5d48ffef 105 SUPERFAMILY SSF47413 8 51 1.24E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS06535 0dea9cb19a1ebef9ab79e60b5d48ffef 105 Gene3D G3DSA:1.10.260.40 9 86 3.2E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS03245 00f333d6e67430398fb8d1de0d2e70ea 153 Pfam PF13452 N-terminal half of MaoC dehydratase 9 127 3.9E-30 T 09-03-2017 ARZXY2_RS03245 00f333d6e67430398fb8d1de0d2e70ea 153 SUPERFAMILY SSF54637 8 152 7.47E-39 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS03245 00f333d6e67430398fb8d1de0d2e70ea 153 PIRSF PIRSF018072 1 153 5.3E-59 T 09-03-2017 IPR016709 Uncharacterised protein family UPF0336 ARZXY2_RS03245 00f333d6e67430398fb8d1de0d2e70ea 153 Hamap MF_00799 UPF0336 protein . 1 152 32.144 T 09-03-2017 IPR016709 Uncharacterised protein family UPF0336 ARZXY2_RS03245 00f333d6e67430398fb8d1de0d2e70ea 153 Gene3D G3DSA:3.10.129.10 1 152 1.7E-45 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 SUPERFAMILY SSF88659 102 169 1.22E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Pfam PF04542 Sigma-70 region 2 28 95 7.7E-15 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 243 6.1E-26 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Gene3D G3DSA:1.10.601.10 26 95 4.7E-14 T 09-03-2017 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 SUPERFAMILY SSF88659 183 245 4.67E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Gene3D G3DSA:1.10.10.10 184 243 1.4E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Gene3D G3DSA:1.10.10.10 97 150 2.5E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Pfam PF04545 Sigma-70, region 4 192 240 8.8E-11 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 Pfam PF04539 Sigma-70 region 3 111 172 4.4E-11 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18125 bcbbb8a58814eaf23242e1befa1cdcfd 256 SUPERFAMILY SSF88946 24 97 1.31E-20 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 SUPERFAMILY SSF81324 11 201 6.28E-36 T 09-03-2017 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 Gene3D G3DSA:1.20.5.110 164 205 3.9E-20 T 09-03-2017 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 PRINTS PR00169 Potassium channel signature 25 45 4.0E-11 T 09-03-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 PRINTS PR00169 Potassium channel signature 81 107 4.0E-11 T 09-03-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 PRINTS PR00169 Potassium channel signature 172 198 4.0E-11 T 09-03-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 PRINTS PR00169 Potassium channel signature 143 165 4.0E-11 T 09-03-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 Gene3D G3DSA:1.10.287.70 114 162 2.0E-14 T 09-03-2017 ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 Pfam PF07885 Ion channel 125 199 3.9E-17 T 09-03-2017 IPR013099 Potassium channel domain ARZXY2_RS03030 fc65e3267410e86bbebab3b8dec0e52c 252 Gene3D G3DSA:1.20.120.350 9 101 2.2E-4 T 09-03-2017 IPR027359 Voltage-dependent channel, four helix bundle domain ARZXY2_RS19180 b8023ee639605b2ea9ee473955b88b33 150 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 20 125 4.0E-9 T 09-03-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 ARZXY2_RS19180 b8023ee639605b2ea9ee473955b88b33 150 Gene3D G3DSA:3.10.450.50 16 129 4.8E-14 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS19180 b8023ee639605b2ea9ee473955b88b33 150 Pfam PF13474 SnoaL-like domain 17 127 2.6E-11 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS19180 b8023ee639605b2ea9ee473955b88b33 150 SUPERFAMILY SSF54427 17 130 3.77E-18 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 761 5.3E-266 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Pfam PF01568 Molydopterin dinucleotide binding domain 648 755 1.2E-10 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 SUPERFAMILY SSF50692 644 766 1.38E-17 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Pfam PF00384 Molybdopterin oxidoreductase 120 492 5.1E-32 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Gene3D G3DSA:3.40.228.10 194 399 2.9E-51 T 09-03-2017 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Gene3D G3DSA:2.40.40.20 644 765 7.4E-11 T 09-03-2017 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 PIRSF PIRSF000144 2 765 0.0 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 SUPERFAMILY SSF53706 59 639 1.7E-129 T 09-03-2017 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Gene3D G3DSA:3.40.50.740 400 633 1.4E-48 T 09-03-2017 ARZXY2_RS07870 14fdb9ef08c3657bdf3506757c07dacf 775 Gene3D G3DSA:3.40.50.740 120 193 1.4E-48 T 09-03-2017 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 Pfam PF01183 Glycosyl hydrolases family 25 191 386 7.2E-46 T 09-03-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 SUPERFAMILY SSF69318 770 900 1.02E-6 T 09-03-2017 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 191 224 - T 09-03-2017 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 Gene3D G3DSA:3.20.20.80 187 404 3.0E-65 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 SUPERFAMILY SSF69318 519 752 1.57E-12 T 09-03-2017 ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 SMART SM00641 187 297 9.7E-25 T 09-03-2017 IPR018077 Glycoside hydrolase, family 25 subgroup ARZXY2_RS04910 4d46e23cc2f8d09c4415f8964238de6d 909 SUPERFAMILY SSF51445 184 403 6.46E-57 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 294 5.3E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 Gene3D G3DSA:3.50.50.60 4 117 5.4E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 09-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 Gene3D G3DSA:3.50.50.60 231 302 1.3E-7 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 SUPERFAMILY SSF51905 6 305 3.24E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.4E-35 T 09-03-2017 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 4.4E-35 T 09-03-2017 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 4.4E-35 T 09-03-2017 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 4.4E-35 T 09-03-2017 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 4.4E-35 T 09-03-2017 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 286 305 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.2E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 305 1.3E-116 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 ARZXY2_RS17680 2bd25aff2bbe3a03f00bb16131d267e1 325 Gene3D G3DSA:3.50.50.60 119 230 3.3E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14480 80e24cf91a85a8264d090af59822ef14 255 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 167 184 - T 09-03-2017 IPR000540 Flagellar motor protein MotA, conserved site ARZXY2_RS14480 80e24cf91a85a8264d090af59822ef14 255 Pfam PF01618 MotA/TolQ/ExbB proton channel family 82 201 2.4E-23 T 09-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 26 533 4.8E-233 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 Gene3D G3DSA:1.20.1220.12 420 528 1.8E-29 T 09-03-2017 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 ProSitePatterns PS00510 Malate synthase signature. 271 286 - T 09-03-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 SUPERFAMILY SSF51645 15 534 2.22E-181 T 09-03-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 PIRSF PIRSF001363 5 536 2.1E-236 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 Pfam PF01274 Malate synthase 22 532 4.5E-196 T 09-03-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS15595 23b8d4176be61059f3db7f257bacd67b 550 Gene3D G3DSA:3.20.20.360 75 419 2.4E-119 T 09-03-2017 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 TIGRFAM TIGR00510 lipA: lipoyl synthase 22 306 4.4E-101 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 PIRSF PIRSF005963 4 318 3.8E-120 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 SUPERFAMILY SSF102114 42 307 5.23E-58 T 09-03-2017 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 Pfam PF04055 Radical SAM superfamily 81 235 7.5E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 SMART SM00729 71 277 4.6E-11 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 135.029 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 3.0E-7 T 09-03-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS19610 64d852c5bebf04b60c916a073f552524 335 Gene3D G3DSA:3.20.20.70 43 302 1.3E-64 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 Gene3D G3DSA:1.10.1040.10 40 325 1.4E-109 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 3.1E-76 T 09-03-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 329 4.7E-128 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 Gene3D G3DSA:3.50.50.60 5 39 5.6E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 SUPERFAMILY SSF51735 3 183 9.51E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 SUPERFAMILY SSF48179 184 332 1.48E-66 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 2.8E-62 T 09-03-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 ARZXY2_RS05635 633a8cce309291cb47ece22d9ed7161e 341 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.597 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 SUPERFAMILY SSF53187 14 207 5.94E-72 T 09-03-2017 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 SUPERFAMILY SSF53187 308 397 5.94E-72 T 09-03-2017 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 Pfam PF07687 Peptidase dimerisation domain 195 293 1.1E-4 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 PIRSF PIRSF005962 14 400 1.7E-97 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 SUPERFAMILY SSF55031 192 309 1.5E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 25 382 7.9E-102 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 Gene3D G3DSA:3.30.70.360 192 307 6.7E-28 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 Gene3D G3DSA:3.40.630.10 13 188 7.2E-89 T 09-03-2017 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 Gene3D G3DSA:3.40.630.10 308 399 7.2E-89 T 09-03-2017 ARZXY2_RS13195 d98872193df7a961fd913709b87413a1 401 Pfam PF01546 Peptidase family M20/M25/M40 80 391 1.1E-29 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 SUPERFAMILY SSF55031 216 327 1.38E-18 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 Gene3D G3DSA:3.40.630.10 11 229 8.4E-87 T 09-03-2017 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 Gene3D G3DSA:3.40.630.10 354 413 8.4E-87 T 09-03-2017 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 PIRSF PIRSF001235 8 415 2.0E-109 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 16 408 3.1E-82 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 SUPERFAMILY SSF53187 13 226 8.2E-71 T 09-03-2017 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 SUPERFAMILY SSF53187 339 412 8.2E-71 T 09-03-2017 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 Pfam PF01546 Peptidase family M20/M25/M40 82 408 1.4E-27 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS15460 564e5242b90993427ebbdbb79293c97f 418 Gene3D G3DSA:3.30.70.360 230 330 1.8E-28 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS20280 40b4725ba21457c9981af0598e96089c 394 SUPERFAMILY SSF69318 122 279 2.09E-25 T 09-03-2017 ARZXY2_RS20280 40b4725ba21457c9981af0598e96089c 394 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 183 243 2.8E-8 T 09-03-2017 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 9.2E-27 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 SMART SM00862 154 230 1.2E-28 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 Gene3D G3DSA:1.10.10.10 131 232 2.4E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 SMART SM00448 8 119 2.4E-46 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 SUPERFAMILY SSF52172 7 132 5.55E-44 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 Pfam PF00072 Response regulator receiver domain 11 120 1.6E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 SUPERFAMILY SSF46894 131 231 5.67E-31 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS14300 8be091530e283079ead9af2b50efba27 236 Gene3D G3DSA:3.40.50.2300 4 128 7.5E-44 T 09-03-2017 ARZXY2_RS05780 cc7cd36a03b195ee1fd48c38706e3b7d 164 Pfam PF12028 Protein of unknown function (DUF3515) 29 140 4.0E-17 T 09-03-2017 IPR021903 Protein of unknown function DUF3515 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.5E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.5E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 Gene3D G3DSA:1.10.10.10 22 83 2.2E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 SUPERFAMILY SSF53383 95 463 2.78E-75 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 82 2.2E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 Gene3D G3DSA:3.90.1150.10 331 460 1.7E-20 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 Gene3D G3DSA:3.40.640.10 142 330 6.4E-41 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 SUPERFAMILY SSF46785 21 84 2.24E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15335 fb0509c43c090ba90265122b71774a23 483 Pfam PF00155 Aminotransferase class I and II 146 457 7.5E-25 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Gene3D G3DSA:3.30.450.40 37 200 3.0E-31 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Gene3D G3DSA:3.30.450.40 233 370 7.2E-7 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Gene3D G3DSA:3.30.565.10 464 569 2.0E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 569 4.1E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 SUPERFAMILY SSF55781 233 367 3.27E-6 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 SUPERFAMILY SSF55874 478 569 1.44E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 SMART SM00387 481 570 1.6E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 SMART SM00065 55 202 8.4E-20 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Pfam PF13185 GAF domain 54 193 1.2E-14 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 Pfam PF07730 Histidine kinase 378 440 5.1E-12 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS09850 2ebb0edbac926dc9004c94b73c39c6ce 570 SUPERFAMILY SSF55781 38 220 4.8E-37 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.2E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.2E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 SUPERFAMILY SSF46785 4 59 3.5E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 Gene3D G3DSA:1.10.10.10 4 56 2.7E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 3.4E-16 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 SUPERFAMILY SSF100950 74 237 3.03E-27 T 09-03-2017 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 SMART SM01134 72 241 3.6E-56 T 09-03-2017 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 SMART SM00420 6 58 2.5E-15 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 Pfam PF00455 DeoR C terminal sensor domain 74 240 2.4E-43 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS12260 2c5f4bf1e2a44e1ebc1db60cd4c3497f 266 Gene3D G3DSA:3.40.50.1360 74 224 7.3E-17 T 09-03-2017 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 51 1.6E-15 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 Gene3D G3DSA:3.30.1390.10 54 126 2.7E-33 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 Gene3D G3DSA:1.20.5.710 3 53 7.2E-17 T 09-03-2017 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 SUPERFAMILY SSF54736 55 126 2.27E-24 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 SUPERFAMILY SSF48300 5 62 1.83E-14 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 126 8.0E-14 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 1.8E-29 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 126 24.394 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03435 c825848ad277df39db1d531beea2eca3 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 9.4E-48 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS08700 00e0c49a9ddcf0e4a51d0fea6f83935e 308 Gene3D G3DSA:3.20.20.100 1 307 1.2E-84 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08700 00e0c49a9ddcf0e4a51d0fea6f83935e 308 SUPERFAMILY SSF51430 1 307 4.98E-83 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08700 00e0c49a9ddcf0e4a51d0fea6f83935e 308 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 136 153 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS08700 00e0c49a9ddcf0e4a51d0fea6f83935e 308 Pfam PF00248 Aldo/keto reductase family 16 305 1.9E-65 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS12940 df65173f42ba3ea7baf053b733c40c01 320 Gene3D G3DSA:3.40.630.30 118 286 1.1E-35 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12940 df65173f42ba3ea7baf053b733c40c01 320 Gene3D G3DSA:3.40.630.30 3 117 9.9E-8 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12940 df65173f42ba3ea7baf053b733c40c01 320 Pfam PF13480 Acetyltransferase (GNAT) domain 140 256 1.3E-17 T 09-03-2017 ARZXY2_RS12940 df65173f42ba3ea7baf053b733c40c01 320 SUPERFAMILY SSF55729 120 301 6.42E-36 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12940 df65173f42ba3ea7baf053b733c40c01 320 SUPERFAMILY SSF55729 2 127 8.35E-10 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 296 7.1E-32 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 SUPERFAMILY SSF48179 202 301 5.95E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Gene3D G3DSA:3.40.50.720 1 205 4.4E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 421 1.4E-28 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 SUPERFAMILY SSF51735 1 187 4.79E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 170 2.9E-57 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 417 1.0E-126 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 SMART SM00984 320 421 1.6E-40 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 SUPERFAMILY SSF52413 313 431 3.01E-33 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Gene3D G3DSA:3.40.50.720 233 437 6.7E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 PIRSF PIRSF500134 1 437 5.0E-150 T 09-03-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 Gene3D G3DSA:1.20.5.100 206 231 6.1E-17 T 09-03-2017 ARZXY2_RS02475 03ab8e8f3a87d687fb25913f524c9170 437 PIRSF PIRSF000124 1 436 1.7E-120 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 Gene3D G3DSA:2.40.37.10 323 485 2.0E-46 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 SUPERFAMILY SSF50621 310 485 7.33E-45 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 Gene3D G3DSA:3.20.20.10 66 322 1.0E-83 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 326 345 1.8E-15 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 1.8E-15 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 442 455 1.8E-15 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 1.8E-15 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 237 250 1.8E-15 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 37 484 6.3E-126 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 362 461 1.7E-13 T 09-03-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 46 485 36.748 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 1.1E-17 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01181 Diaminopimelate decarboxylase signature 369 387 1.1E-17 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 PRINTS PR01181 Diaminopimelate decarboxylase signature 452 474 1.1E-17 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 09-03-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 SUPERFAMILY SSF51419 57 337 6.11E-67 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS05165 75391a803b45f2effd34ed4c782ff2d1 490 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 88 336 2.7E-53 T 09-03-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.9E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 Pfam PF13377 Periplasmic binding protein-like domain 170 331 2.0E-34 T 09-03-2017 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 Gene3D G3DSA:3.40.50.2300 168 332 9.7E-49 T 09-03-2017 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 SMART SM00354 2 72 1.3E-25 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 SUPERFAMILY SSF47413 2 60 1.64E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 Gene3D G3DSA:1.10.260.40 3 54 4.4E-24 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 Gene3D G3DSA:3.40.50.2300 55 167 4.8E-28 T 09-03-2017 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 5.0E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.0E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 SUPERFAMILY SSF53822 62 332 8.14E-58 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS15730 2096b9cf8cadb8ff9aa427bd5165c1c2 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 09-03-2017 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Gene3D G3DSA:1.10.1040.10 654 697 6.2E-6 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Gene3D G3DSA:3.40.50.720 339 529 2.7E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 345 524 6.0E-58 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 528 607 1.8E-13 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 SUPERFAMILY SSF48179 527 608 7.57E-16 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 SUPERFAMILY SSF52096 268 321 7.29E-34 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 SUPERFAMILY SSF52096 46 229 7.29E-34 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Gene3D G3DSA:3.90.226.10 33 235 1.1E-31 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 36 233 8.3E-16 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 SUPERFAMILY SSF48179 639 701 9.35E-12 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 SUPERFAMILY SSF51735 343 524 3.59E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10485 e0ba0e38189db945c8edf4e30fc3cdba 714 Gene3D G3DSA:1.10.1040.10 530 605 1.6E-13 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS01910 55a4b06af34b83ae791a60dcdf92d57f 276 Pfam PF01261 Xylose isomerase-like TIM barrel 32 218 2.2E-18 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS01910 55a4b06af34b83ae791a60dcdf92d57f 276 Gene3D G3DSA:3.20.20.150 10 267 2.0E-41 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS01910 55a4b06af34b83ae791a60dcdf92d57f 276 SUPERFAMILY SSF51658 13 264 6.94E-43 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 83 8.2E-10 T 09-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 45 61 8.2E-10 T 09-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 288 306 8.2E-10 T 09-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 SUPERFAMILY SSF53822 45 411 2.02E-59 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 Pfam PF13458 Periplasmic binding protein 45 402 8.0E-50 T 09-03-2017 IPR028081 Leucine-binding protein domain ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 Gene3D G3DSA:3.40.50.2300 194 333 1.9E-20 T 09-03-2017 ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 Gene3D G3DSA:3.40.50.2300 334 385 5.6E-33 T 09-03-2017 ARZXY2_RS16435 c7caa0b9a51c8f98f248120c2a8e9d75 425 Gene3D G3DSA:3.40.50.2300 40 173 5.6E-33 T 09-03-2017 ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 SUPERFAMILY SSF51735 10 252 1.43E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 Gene3D G3DSA:3.40.50.720 9 250 9.5E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.1E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17500 b86b0d90b33b9f8fdb40adc008fedc19 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 6.4E-55 T 09-03-2017 ARZXY2_RS15140 c905f2a60abe86b5dec2f2659aa5a714 301 Gene3D G3DSA:1.10.3720.10 76 291 8.0E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15140 c905f2a60abe86b5dec2f2659aa5a714 301 SUPERFAMILY SSF161098 76 284 3.27E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15140 c905f2a60abe86b5dec2f2659aa5a714 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 299 4.2E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05595 d0f84936c4bbb8af7e9ea36ece2aac70 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site ARZXY2_RS05595 d0f84936c4bbb8af7e9ea36ece2aac70 142 SUPERFAMILY SSF46785 9 117 4.49E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05595 d0f84936c4bbb8af7e9ea36ece2aac70 142 Pfam PF01047 MarR family 40 90 7.0E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05595 d0f84936c4bbb8af7e9ea36ece2aac70 142 SMART SM00347 26 124 8.0E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05595 d0f84936c4bbb8af7e9ea36ece2aac70 142 Gene3D G3DSA:1.10.10.10 4 117 1.2E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 PIRSF PIRSF039085 14 267 4.4E-105 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 Pfam PF00005 ABC transporter 33 191 1.0E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 SUPERFAMILY SSF52540 17 261 2.6E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 SMART SM00382 42 239 2.2E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS14185 ddf0e7359282296a93cfbd3f6d6e8f49 269 Gene3D G3DSA:3.40.50.300 16 262 1.8E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05765 7eaf1c3a3d2c1905580f4d69b23c5b04 245 Gene3D G3DSA:3.40.1130.10 19 223 1.1E-23 T 09-03-2017 ARZXY2_RS05765 7eaf1c3a3d2c1905580f4d69b23c5b04 245 SUPERFAMILY SSF69593 12 235 3.53E-45 T 09-03-2017 ARZXY2_RS05765 7eaf1c3a3d2c1905580f4d69b23c5b04 245 SMART SM00563 41 159 5.6E-35 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS05765 7eaf1c3a3d2c1905580f4d69b23c5b04 245 Pfam PF01553 Acyltransferase 31 156 2.9E-27 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 SUPERFAMILY SSF46689 11 60 6.27E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 Pfam PF12833 Helix-turn-helix domain 33 109 1.9E-20 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 Gene3D G3DSA:1.10.10.60 10 64 1.4E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 SMART SM00342 26 108 3.8E-27 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 SUPERFAMILY SSF46689 62 109 1.84E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS17190 9acf02a8f1fa26b54e8da7aafe08021a 140 Gene3D G3DSA:1.10.10.60 65 111 5.3E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 Gene3D G3DSA:3.40.50.720 27 264 5.6E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 SMART SM00450 297 394 2.2E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 Pfam PF00899 ThiF family 32 264 3.7E-60 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 Pfam PF00581 Rhodanese-like domain 293 390 2.9E-13 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 Gene3D G3DSA:3.40.250.10 288 394 4.5E-24 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS04450 643f4711869fa68da0c1a8fa5544dfcb 399 SUPERFAMILY SSF69572 19 363 1.96E-89 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 424 438 - T 09-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Pfam PF16353 Domain of unknown function(DUF4981) 624 715 1.5E-17 T 09-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Gene3D G3DSA:2.60.40.320 623 716 2.1E-20 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 349 367 5.9E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 145 160 5.9E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 318 332 5.9E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 424 439 5.9E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 511 526 5.9E-32 T 09-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SUPERFAMILY SSF49303 617 718 7.91E-21 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Gene3D G3DSA:2.70.98.10 762 1026 1.1E-58 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 309 607 3.0E-100 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SUPERFAMILY SSF49303 220 308 1.51E-13 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SMART SM01038 743 1026 5.0E-58 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 36 217 2.9E-42 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SUPERFAMILY SSF74650 751 1025 3.3E-68 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 359 384 - T 09-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SUPERFAMILY SSF51445 309 602 1.01E-94 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Gene3D G3DSA:3.20.20.80 308 603 2.3E-96 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Gene3D G3DSA:2.60.120.260 31 206 1.3E-62 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 SUPERFAMILY SSF49785 19 217 8.22E-61 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Gene3D G3DSA:2.60.40.320 207 307 5.0E-13 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 ARZXY2_RS03110 3a03047deab0bdf158ae547da3436765 1030 Pfam PF02929 Beta galactosidase small chain 762 1019 5.7E-46 T 09-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS02395 973ce5bce8716944661a947783020b2f 305 PIRSF PIRSF037834 53 305 6.2E-97 T 09-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 ARZXY2_RS02395 973ce5bce8716944661a947783020b2f 305 Pfam PF05138 Phenylacetic acid catabolic protein 59 305 1.5E-90 T 09-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 ARZXY2_RS02395 973ce5bce8716944661a947783020b2f 305 Gene3D G3DSA:1.20.1260.10 59 305 5.6E-91 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS02395 973ce5bce8716944661a947783020b2f 305 SUPERFAMILY SSF47240 62 298 5.68E-76 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS02395 973ce5bce8716944661a947783020b2f 305 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 69 305 1.4E-91 T 09-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 SMART SM00095 1 112 2.5E-7 T 09-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 4 113 2.3E-40 T 09-03-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 Pfam PF00576 HIUase/Transthyretin family 6 112 8.3E-37 T 09-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 Gene3D G3DSA:2.60.40.180 2 113 1.4E-40 T 09-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 ProSitePatterns PS00768 Transthyretin signature 1. 9 24 - T 09-03-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 SUPERFAMILY SSF49472 2 113 9.42E-41 T 09-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 PRINTS PR00189 Transthyretin signature 37 62 1.2E-8 T 09-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 PRINTS PR00189 Transthyretin signature 5 25 1.2E-8 T 09-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS01140 8846ca5ea710b7aa91c3b4ab471caf34 113 PRINTS PR00189 Transthyretin signature 91 113 1.2E-8 T 09-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 Pfam PF13242 HAD-hyrolase-like 188 261 1.3E-16 T 09-03-2017 ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 12 235 1.3E-34 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 Gene3D G3DSA:3.40.50.1000 5 81 2.9E-39 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 Gene3D G3DSA:3.40.50.1000 187 262 2.9E-39 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 Pfam PF13344 Haloacid dehalogenase-like hydrolase 12 113 5.2E-22 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 Gene3D G3DSA:3.40.50.10410 82 186 1.1E-26 T 09-03-2017 IPR023215 Nitrophenylphosphatase-like domain ARZXY2_RS11140 4a790e1531a1bfc50c5a305839cc38fd 328 SUPERFAMILY SSF56784 9 262 4.38E-54 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18315 91758413fb9e3e012244235da2ef4b26 417 Pfam PF01565 FAD binding domain 13 142 1.6E-18 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS18315 91758413fb9e3e012244235da2ef4b26 417 SUPERFAMILY SSF56176 2 171 2.33E-32 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS18315 91758413fb9e3e012244235da2ef4b26 417 Pfam PF04030 D-arabinono-1,4-lactone oxidase 281 406 3.5E-21 T 09-03-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 ARZXY2_RS18315 91758413fb9e3e012244235da2ef4b26 417 Gene3D G3DSA:3.30.465.10 63 170 3.3E-25 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS18315 91758413fb9e3e012244235da2ef4b26 417 Gene3D G3DSA:3.30.43.10 2 54 8.8E-10 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 SUPERFAMILY SSF52029 184 374 4.78E-81 T 09-03-2017 IPR027409 GroEL-like apical domain ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 09-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 5.8E-244 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 Gene3D G3DSA:1.10.560.10 6 194 1.7E-47 T 09-03-2017 IPR027413 GroEL-like equatorial domain ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 Gene3D G3DSA:3.50.7.10 195 368 7.0E-92 T 09-03-2017 IPR027409 GroEL-like apical domain ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 Gene3D G3DSA:1.10.560.10 369 516 7.5E-35 T 09-03-2017 IPR027413 GroEL-like equatorial domain ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 6.5E-92 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 SUPERFAMILY SSF54849 136 203 2.2E-26 T 09-03-2017 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 PRINTS PR00298 60kDa chaperonin signature 348 373 1.5E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 PRINTS PR00298 60kDa chaperonin signature 266 289 1.5E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 PRINTS PR00298 60kDa chaperonin signature 396 417 1.5E-69 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 SUPERFAMILY SSF48592 6 133 5.66E-70 T 09-03-2017 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 SUPERFAMILY SSF48592 404 519 5.66E-70 T 09-03-2017 ARZXY2_RS14320 7c4516bcae43a76f359517aadce6eb49 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 40.785 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS09825 15c4343c21383904551c7b369827fa79 140 Gene3D G3DSA:2.30.110.10 2 139 1.4E-44 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09825 15c4343c21383904551c7b369827fa79 140 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 129 4.5E-24 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS09825 15c4343c21383904551c7b369827fa79 140 SUPERFAMILY SSF50475 9 131 1.13E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.5E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.5E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 SUPERFAMILY SSF46785 3 72 2.25E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 6.2E-22 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 SMART SM00345 9 68 1.4E-21 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 Pfam PF07729 FCD domain 93 220 1.7E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 Gene3D G3DSA:1.10.10.10 3 71 2.4E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 Gene3D G3DSA:1.20.120.530 88 229 1.9E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 SUPERFAMILY SSF48008 89 227 2.75E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18395 158f706193fe1d1831740d06cf78260a 232 SMART SM00895 93 221 4.4E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS01760 38978c6cea91dcab2873dfd29540d444 320 SUPERFAMILY SSF161098 82 307 2.49E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01760 38978c6cea91dcab2873dfd29540d444 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 311 6.7E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01760 38978c6cea91dcab2873dfd29540d444 320 Gene3D G3DSA:1.10.3720.10 87 315 1.7E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15700 40358e339d74a0d385b834a3085073ef 357 Gene3D G3DSA:3.40.50.2000 172 306 2.9E-16 T 09-03-2017 ARZXY2_RS15700 40358e339d74a0d385b834a3085073ef 357 SUPERFAMILY SSF53756 12 336 6.85E-55 T 09-03-2017 ARZXY2_RS15700 40358e339d74a0d385b834a3085073ef 357 Pfam PF00534 Glycosyl transferases group 1 171 309 1.7E-17 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS15700 40358e339d74a0d385b834a3085073ef 357 Pfam PF13439 Glycosyltransferase Family 4 18 159 3.3E-16 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 SUPERFAMILY SSF51735 1 241 3.31E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 Gene3D G3DSA:3.40.50.720 2 229 2.1E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 Pfam PF00106 short chain dehydrogenase 7 190 2.3E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08915 149d56e1c7c401d5339568345d8b4728 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 8.1E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 27 38 8.1E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 119 132 8.1E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 8.1E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 SUPERFAMILY SSF56784 27 222 1.18E-41 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 30 206 1.5E-25 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 206 2.3E-16 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 Gene3D G3DSA:3.40.50.1000 28 42 2.2E-37 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00740 17b5618e7861e1328abd2cc9cfa0de7b 236 Gene3D G3DSA:3.40.50.1000 108 224 2.2E-37 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS05380 ec5d75c2424133c40cc12cfc4fa95ca1 265 Gene3D G3DSA:3.60.15.10 1 262 5.9E-53 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05380 ec5d75c2424133c40cc12cfc4fa95ca1 265 SUPERFAMILY SSF56281 1 263 1.57E-48 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05380 ec5d75c2424133c40cc12cfc4fa95ca1 265 Pfam PF12706 Beta-lactamase superfamily domain 50 233 2.8E-20 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05380 ec5d75c2424133c40cc12cfc4fa95ca1 265 SMART SM00849 18 232 0.0071 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 PRINTS PR00124 ATP synthase C subunit signature 26 41 2.8E-18 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 PRINTS PR00124 ATP synthase C subunit signature 5 24 2.8E-18 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 PRINTS PR00124 ATP synthase C subunit signature 43 67 2.8E-18 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 SUPERFAMILY SSF81333 9 67 6.02E-16 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 67 3.1E-12 T 09-03-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 Gene3D G3DSA:1.20.20.10 8 67 3.5E-21 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 09-03-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 Hamap MF_01396 ATP synthase subunit c [atpH]. 2 67 11.473 T 09-03-2017 ARZXY2_RS05235 ec1ffd2ff40d1809fd2dca9acf61ce68 67 Pfam PF00137 ATP synthase subunit C 10 67 1.5E-12 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 SUPERFAMILY SSF53098 141 320 1.39E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS01175 2b448163888a8c75cc1d3fe17e833386 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 SMART SM00529 26 125 9.4E-40 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Gene3D G3DSA:1.10.10.10 2 72 6.1E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Gene3D G3DSA:1.10.60.10 75 133 3.9E-30 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 SUPERFAMILY SSF50037 130 229 1.31E-20 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Pfam PF04023 FeoA domain 162 229 6.5E-8 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 SUPERFAMILY SSF47979 65 135 1.2E-25 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 SUPERFAMILY SSF46785 2 62 1.82E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 1.6E-28 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 SMART SM00899 151 230 9.6E-5 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 4.8E-18 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 ARZXY2_RS14240 5a80ac38f14c770f291b7d9f32ea928d 231 Gene3D G3DSA:2.30.30.90 134 229 8.0E-23 T 09-03-2017 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 SUPERFAMILY SSF63867 351 413 6.54E-6 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Pfam PF03453 MoeA N-terminal region (domain I and II) 15 170 4.3E-26 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Pfam PF03454 MoeA C-terminal region (domain IV) 352 410 4.9E-6 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Gene3D G3DSA:2.40.340.10 353 400 2.4E-6 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 SUPERFAMILY SSF63882 13 178 2.49E-31 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 263 276 - T 09-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Gene3D G3DSA:3.90.105.10 138 165 2.7E-11 T 09-03-2017 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Gene3D G3DSA:3.40.980.10 166 339 1.8E-40 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Gene3D G3DSA:2.170.190.11 55 137 4.2E-8 T 09-03-2017 ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 SUPERFAMILY SSF53218 182 338 3.93E-23 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 SMART SM00852 183 337 9.9E-21 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS14210 a7659307ce54ef0eba350d42d876aee7 452 Pfam PF00994 Probable molybdopterin binding domain 185 333 6.8E-15 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS08710 fe3ba35e32234e44fa5e01e4ee36c135 332 Gene3D G3DSA:3.90.25.10 181 321 1.4E-46 T 09-03-2017 ARZXY2_RS08710 fe3ba35e32234e44fa5e01e4ee36c135 332 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 318 7.8E-136 T 09-03-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 ARZXY2_RS08710 fe3ba35e32234e44fa5e01e4ee36c135 332 SUPERFAMILY SSF51735 1 320 1.12E-91 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08710 fe3ba35e32234e44fa5e01e4ee36c135 332 Gene3D G3DSA:3.40.50.720 1 180 1.9E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08710 fe3ba35e32234e44fa5e01e4ee36c135 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 296 2.3E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11080 06658ce49966f40726e457e1b71dddab 506 Gene3D G3DSA:3.30.1330.120 286 432 7.3E-47 T 09-03-2017 ARZXY2_RS11080 06658ce49966f40726e457e1b71dddab 506 SUPERFAMILY SSF103378 19 487 2.35E-127 T 09-03-2017 IPR005656 MmgE/PrpD GO:0016829 ARZXY2_RS11080 06658ce49966f40726e457e1b71dddab 506 Pfam PF03972 MmgE/PrpD family 20 476 1.2E-130 T 09-03-2017 IPR005656 MmgE/PrpD GO:0016829 ARZXY2_RS18480 2c57a3119797efe01a627e4f736a897b 238 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 27 233 9.8E-54 T 09-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like ARZXY2_RS18480 2c57a3119797efe01a627e4f736a897b 238 Gene3D G3DSA:2.60.120.590 25 233 2.6E-52 T 09-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like ARZXY2_RS18480 2c57a3119797efe01a627e4f736a897b 238 SUPERFAMILY SSF51197 25 234 5.49E-46 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Gene3D G3DSA:3.40.50.1000 452 494 5.0E-50 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Gene3D G3DSA:3.40.50.1000 614 756 5.0E-50 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 252 508 3.4E-43 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 587 771 4.3E-41 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Gene3D G3DSA:3.30.70.100 10 78 5.9E-21 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF56784 477 497 3.09E-53 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF56784 583 788 3.09E-53 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Gene3D G3DSA:3.40.1110.10 495 613 5.4E-20 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Gene3D G3DSA:2.70.150.10 205 380 6.9E-29 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 206 790 1.6E-182 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 481 487 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Pfam PF00122 E1-E2 ATPase 251 470 8.4E-66 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 ProSitePatterns PS01047 Heavy-metal-associated domain. 19 47 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF81665 247 283 9.15E-15 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF81665 380 472 9.15E-15 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 711 723 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 611 622 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 688 707 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 493 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 643 1.8E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF55008 8 82 1.83E-17 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 SUPERFAMILY SSF81653 285 379 1.11E-24 T 09-03-2017 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Pfam PF00403 Heavy-metal-associated domain 17 75 6.7E-10 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS18955 d9b9e962475f86e1c24e6ff2a0349d85 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 475 702 4.6E-39 T 09-03-2017 ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 Gene3D G3DSA:3.30.450.40 84 255 7.7E-40 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 SUPERFAMILY SSF46785 13 82 7.44E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 SUPERFAMILY SSF55781 76 254 1.44E-38 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 SMART SM00346 11 100 4.9E-16 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 Pfam PF09339 IclR helix-turn-helix domain 14 60 3.4E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 Gene3D G3DSA:1.10.10.10 10 83 1.2E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00880 c24e64484b2091cef57648c27049f385 271 Pfam PF01614 Bacterial transcriptional regulator 131 251 2.8E-18 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS00780 e8d08bfb9b20e7c49bd058bbcc8f8216 201 PIRSF PIRSF019325 6 201 5.5E-73 T 09-03-2017 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 ARZXY2_RS00780 e8d08bfb9b20e7c49bd058bbcc8f8216 201 SUPERFAMILY SSF51182 17 200 5.63E-36 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS00780 e8d08bfb9b20e7c49bd058bbcc8f8216 201 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 35 185 1.6E-28 T 09-03-2017 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 ARZXY2_RS00780 e8d08bfb9b20e7c49bd058bbcc8f8216 201 Gene3D G3DSA:2.60.120.10 25 200 3.1E-41 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS16510 310352ff3bd93c31b288ea6d1f2c8dd8 192 Gene3D G3DSA:3.40.630.30 37 190 5.2E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS16510 310352ff3bd93c31b288ea6d1f2c8dd8 192 Pfam PF00583 Acetyltransferase (GNAT) family 66 168 3.9E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS16510 310352ff3bd93c31b288ea6d1f2c8dd8 192 SUPERFAMILY SSF55729 50 189 6.35E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 ProSitePatterns PS00211 ABC transporters family signature. 524 538 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 Pfam PF00664 ABC transporter transmembrane region 44 314 6.3E-41 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 SMART SM00382 406 598 9.2E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 SUPERFAMILY SSF90123 30 350 5.89E-71 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 Pfam PF00005 ABC transporter 397 552 1.9E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 Gene3D G3DSA:3.40.50.300 361 616 1.1E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 Gene3D G3DSA:1.20.1560.10 30 350 8.4E-72 T 09-03-2017 ARZXY2_RS14155 dfd2a5fe3d3b519b89512425de66c020 633 SUPERFAMILY SSF52540 351 623 5.1E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 84 99 5.3E-28 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 257 273 5.3E-28 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 239 257 5.3E-28 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 221 237 5.3E-28 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 206 221 5.3E-28 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 Gene3D G3DSA:3.30.9.10 254 277 3.9E-16 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 Gene3D G3DSA:3.30.9.10 96 199 3.9E-16 T 09-03-2017 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 Pfam PF01494 FAD binding domain 27 270 5.8E-49 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 SUPERFAMILY SSF51905 193 306 1.46E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 SUPERFAMILY SSF51905 7 105 1.46E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 Gene3D G3DSA:3.50.50.60 204 244 6.0E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19155 9b5648dec9a43aa77db25de4b62d6dfc 462 Gene3D G3DSA:3.50.50.60 22 95 6.0E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 1.2E-35 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 201 1.7E-30 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 1 639 1.7E-252 T 09-03-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 420 595 8.2E-34 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Gene3D G3DSA:3.40.50.970 414 613 1.8E-46 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 SUPERFAMILY SSF52518 1 214 2.62E-25 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 SUPERFAMILY SSF52467 188 367 2.5E-44 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Gene3D G3DSA:3.40.50.970 1 214 3.5E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 SUPERFAMILY SSF52518 401 628 2.03E-42 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS14080 b60c96f59d05195839ee7de02e02e0c4 642 Gene3D G3DSA:3.40.50.1220 215 413 6.4E-52 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 77 8.0E-10 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 SUPERFAMILY SSF52540 351 607 2.66E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 Gene3D G3DSA:3.40.50.300 347 611 4.7E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 SUPERFAMILY SSF161098 93 280 1.3E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 296 2.3E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 Gene3D G3DSA:1.10.3720.10 90 295 4.0E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 Pfam PF00005 ABC transporter 373 535 2.8E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS16245 87fb9ba0d148d96112d3e93d09c11520 646 SMART SM00382 381 585 1.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13895 e05b44d5ee1ab97e7dce70a9b995f642 268 SUPERFAMILY SSF52096 9 268 1.22E-75 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS13895 e05b44d5ee1ab97e7dce70a9b995f642 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 267 3.5E-57 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS13895 e05b44d5ee1ab97e7dce70a9b995f642 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 109 129 - T 09-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 ARZXY2_RS13895 e05b44d5ee1ab97e7dce70a9b995f642 268 Gene3D G3DSA:3.90.226.10 7 207 1.1E-59 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS13895 e05b44d5ee1ab97e7dce70a9b995f642 268 Gene3D G3DSA:1.10.12.10 211 268 6.2E-17 T 09-03-2017 IPR014748 Crontonase, C-terminal ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 SUPERFAMILY SSF53067 18 259 8.42E-46 T 09-03-2017 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 SUPERFAMILY SSF53067 265 463 7.12E-32 T 09-03-2017 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 20 257 1.8E-28 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 268 459 8.1E-30 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 Gene3D G3DSA:3.30.420.40 17 257 2.4E-28 T 09-03-2017 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 Gene3D G3DSA:3.30.420.40 380 477 2.1E-13 T 09-03-2017 ARZXY2_RS00195 8e85b4161b2c8dd20857e76570bc06d8 502 PIRSF PIRSF000538 17 489 4.0E-39 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS04870 f05352f281e289799da4ecd116e9932b 243 Pfam PF00005 ABC transporter 44 175 1.5E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04870 f05352f281e289799da4ecd116e9932b 243 SUPERFAMILY SSF52540 40 235 4.89E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04870 f05352f281e289799da4ecd116e9932b 243 SMART SM00382 53 224 2.1E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04870 f05352f281e289799da4ecd116e9932b 243 Gene3D G3DSA:3.40.50.300 4 236 6.5E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07670 7ce19c2e6d3c890e20b8b830bbde3b82 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 3 101 7.5E-30 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07670 7ce19c2e6d3c890e20b8b830bbde3b82 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 3 101 8.9E-23 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07670 7ce19c2e6d3c890e20b8b830bbde3b82 102 SUPERFAMILY SSF141091 2 101 6.02E-30 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07670 7ce19c2e6d3c890e20b8b830bbde3b82 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 09-03-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS07670 7ce19c2e6d3c890e20b8b830bbde3b82 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 2 102 18.953 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 25 187 2.5E-40 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 SUPERFAMILY SSF52467 173 364 4.5E-29 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 SUPERFAMILY SSF52518 384 562 6.79E-37 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Gene3D G3DSA:3.40.50.970 23 196 8.5E-39 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 552 2.2E-20 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 210 340 1.1E-19 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Gene3D G3DSA:3.40.50.970 381 561 1.3E-37 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 SUPERFAMILY SSF52518 23 198 4.36E-37 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09460 98835bee5b8793a1ccf907b84de5f689 571 Gene3D G3DSA:3.40.50.1220 203 367 6.9E-27 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 SUPERFAMILY SSF53383 4 430 8.35E-111 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 278 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 Pfam PF00202 Aminotransferase class-III 39 427 3.0E-74 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 Gene3D G3DSA:3.90.1150.10 326 431 6.9E-37 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 Gene3D G3DSA:3.90.1150.10 3 73 6.9E-37 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 434 95.57 T 09-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 Gene3D G3DSA:3.40.640.10 74 322 9.6E-71 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS04500 413faadec25791a63e98251edd3e02c1 439 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 430 1.1E-167 T 09-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Pfam PF01751 Toprim domain 470 580 6.5E-15 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 ProSitePatterns PS00177 DNA topoisomerase II signature. 473 481 - T 09-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Gene3D G3DSA:3.40.50.670 455 673 2.0E-88 T 09-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 30 691 9.2E-289 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 30 40 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 293 311 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 644 656 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 411 425 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 425 445 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 363 379 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 267 289 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 660 676 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 521 530 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 205 220 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR01159 DNA gyrase subunit B signature 220 233 8.5E-70 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 27 691 87.32 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 537 553 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 575 587 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 94 107 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 319 332 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 137 151 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 555 572 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 623 639 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 471 485 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 PRINTS PR00418 DNA topoisomerase II family signature 59 74 7.8E-67 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Gene3D G3DSA:3.30.565.10 30 236 4.5E-86 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 SUPERFAMILY SSF54211 268 441 1.44E-56 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 621 680 4.1E-27 T 09-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 SUPERFAMILY SSF55874 30 234 1.0E-67 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 SMART SM00433 59 684 0.0 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Gene3D G3DSA:3.30.230.10 267 441 8.4E-72 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 SMART SM00387 55 200 1.2E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 SUPERFAMILY SSF56719 445 686 3.14E-84 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 57 197 1.6E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS18545 c68db40cdee1b031b599891f13184fbd 691 Pfam PF00204 DNA gyrase B 268 441 3.8E-64 T 09-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS02820 42a54b0179a3dd81c8645242e66d0f47 367 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 244 256 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS02820 42a54b0179a3dd81c8645242e66d0f47 367 SUPERFAMILY SSF48576 51 366 2.7E-77 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS02820 42a54b0179a3dd81c8645242e66d0f47 367 Pfam PF00348 Polyprenyl synthetase 75 288 6.4E-55 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS02820 42a54b0179a3dd81c8645242e66d0f47 367 Gene3D G3DSA:1.10.600.10 52 366 2.8E-83 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS10795 c694cdfa1277b9b3fa649a73d6c92170 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 302 1.1E-83 T 09-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS10795 c694cdfa1277b9b3fa649a73d6c92170 308 SUPERFAMILY SSF55120 76 303 2.88E-71 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS10795 c694cdfa1277b9b3fa649a73d6c92170 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 09-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS10795 c694cdfa1277b9b3fa649a73d6c92170 308 Pfam PF00849 RNA pseudouridylate synthase 88 242 2.6E-33 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Pfam PF03793 PASTA domain 625 682 8.5E-8 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Pfam PF03793 PASTA domain 559 620 8.6E-13 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Pfam PF03793 PASTA domain 423 484 1.1E-11 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Pfam PF03793 PASTA domain 491 552 7.9E-14 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Gene3D G3DSA:1.10.510.10 85 273 8.5E-52 T 09-03-2017 ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Pfam PF00069 Protein kinase domain 18 262 2.5E-52 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 Gene3D G3DSA:3.30.200.20 9 84 4.5E-26 T 09-03-2017 ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SUPERFAMILY SSF56112 15 349 5.8E-78 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SMART SM00740 553 620 3.0E-12 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SMART SM00740 485 552 4.0E-11 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SMART SM00740 621 683 2.1E-10 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SMART SM00740 418 484 6.5E-9 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS10925 3fc5b144704d72e55fa5cace246cb189 683 SMART SM00220 18 277 1.4E-56 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 Gene3D G3DSA:3.40.1410.10 79 246 5.0E-50 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 SUPERFAMILY SSF64288 71 246 6.75E-48 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 Pfam PF07702 UTRA domain 102 239 8.9E-38 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 SUPERFAMILY SSF46785 12 85 9.92E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 9.0E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 9.0E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 SMART SM00345 23 81 5.0E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 81 2.1E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 Gene3D G3DSA:1.10.10.10 11 78 4.6E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08400 dabdcc610303aab0cc34fa822837b534 262 SMART SM00866 101 239 2.1E-42 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF141259 515 596 2.88E-15 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Pfam PF03461 TRCF domain 1057 1144 1.0E-22 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SMART SM00982 1056 1153 6.2E-34 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Pfam PF00270 DEAD/DEAH box helicase 659 819 7.7E-19 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF52540 38 342 2.83E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Pfam PF02559 CarD-like/TRCF domain 523 628 1.1E-29 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Gene3D G3DSA:3.40.50.300 642 839 1.1E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Gene3D G3DSA:3.40.50.300 856 1009 3.5E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SMART SM01058 522 629 1.3E-44 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1149 28.547 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SMART SM00490 879 963 1.4E-17 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Gene3D G3DSA:3.30.2060.10 156 231 1.2E-15 T 09-03-2017 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF143517 1041 1198 2.48E-33 T 09-03-2017 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF52540 398 509 2.66E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 174 1129 0.0 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 Pfam PF00271 Helicase conserved C-terminal domain 863 962 3.5E-15 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF52540 835 1043 6.23E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SUPERFAMILY SSF52540 579 836 1.07E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12710 8512e04ff4cc14e420e875f8abef0548 1207 SMART SM00487 653 843 4.5E-33 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 Gene3D G3DSA:3.40.50.720 1 140 2.9E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 SUPERFAMILY SSF51735 2 157 2.32E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 SUPERFAMILY SSF55347 131 272 8.83E-31 T 09-03-2017 ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 Gene3D G3DSA:3.30.360.10 310 364 2.4E-42 T 09-03-2017 ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 Gene3D G3DSA:3.30.360.10 141 263 2.4E-42 T 09-03-2017 ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 118 3.7E-13 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS16230 b47d7bf1350a70c22c882bc45793f5bc 388 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 240 5.1E-9 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16910 efeb979c5183d319e8550f5eff1e311f 262 Gene3D G3DSA:3.20.20.150 3 243 2.3E-60 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16910 efeb979c5183d319e8550f5eff1e311f 262 Pfam PF01261 Xylose isomerase-like TIM barrel 44 216 7.6E-22 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16910 efeb979c5183d319e8550f5eff1e311f 262 PIRSF PIRSF006241 1 261 1.6E-60 T 09-03-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 ARZXY2_RS16910 efeb979c5183d319e8550f5eff1e311f 262 SUPERFAMILY SSF51658 3 241 3.04E-55 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS07765 26747c6b8ccd6cb43d6fb288a78f1540 317 Gene3D G3DSA:3.40.50.410 75 197 3.3E-10 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07765 26747c6b8ccd6cb43d6fb288a78f1540 317 SUPERFAMILY SSF53300 75 208 2.37E-14 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07765 26747c6b8ccd6cb43d6fb288a78f1540 317 SMART SM00327 75 248 6.2E-7 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07765 26747c6b8ccd6cb43d6fb288a78f1540 317 Pfam PF13519 von Willebrand factor type A domain 79 192 1.4E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS17855 ee5f91a7bb97eccde7c8f76e312bc5c3 108 Pfam PF11774 Lsr2 1 106 3.3E-39 T 09-03-2017 IPR024412 Lsr2 ARZXY2_RS17855 ee5f91a7bb97eccde7c8f76e312bc5c3 108 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 107 7.0E-39 T 09-03-2017 IPR024412 Lsr2 ARZXY2_RS00475 223c197334453b9eca64da81af4ee61e 160 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 104 5.7E-14 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ARZXY2_RS00475 223c197334453b9eca64da81af4ee61e 160 Gene3D G3DSA:1.20.1290.10 16 155 1.1E-34 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS00475 223c197334453b9eca64da81af4ee61e 160 SUPERFAMILY SSF69118 17 155 2.49E-31 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 ARZXY2_RS00475 223c197334453b9eca64da81af4ee61e 160 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 84 4.4E-13 T 09-03-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 SUPERFAMILY SSF51905 5 221 1.42E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 SUPERFAMILY SSF51905 314 369 1.42E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 Gene3D G3DSA:3.50.50.60 3 82 3.6E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 Gene3D G3DSA:3.50.50.60 314 369 3.6E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 Gene3D G3DSA:3.50.50.60 138 220 3.6E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16095 7c42203c82b35c28e12b68bb380f825e 370 Pfam PF01266 FAD dependent oxidoreductase 6 348 4.0E-37 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 Gene3D G3DSA:3.10.310.10 131 272 3.0E-39 T 09-03-2017 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 9 279 5.2E-51 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 SUPERFAMILY SSF54506 9 283 3.87E-70 T 09-03-2017 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 PIRSF PIRSF016184 7 283 5.1E-65 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 Gene3D G3DSA:3.10.310.10 9 130 6.7E-42 T 09-03-2017 ARZXY2_RS18805 24bdb312384476a23c326c0ce5780ea8 283 Pfam PF02567 Phenazine biosynthesis-like protein 14 278 1.6E-50 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 ARZXY2_RS04475 d5b6986ef4e2e703e1470004bbf8af85 407 Gene3D G3DSA:3.40.50.1400 202 349 1.7E-41 T 09-03-2017 ARZXY2_RS04475 d5b6986ef4e2e703e1470004bbf8af85 407 Gene3D G3DSA:3.40.50.1400 22 176 7.6E-35 T 09-03-2017 ARZXY2_RS04475 d5b6986ef4e2e703e1470004bbf8af85 407 SUPERFAMILY SSF53800 22 380 2.94E-75 T 09-03-2017 ARZXY2_RS04475 d5b6986ef4e2e703e1470004bbf8af85 407 Pfam PF00762 Ferrochelatase 25 349 6.8E-89 T 09-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ARZXY2_RS04475 d5b6986ef4e2e703e1470004bbf8af85 407 Hamap MF_00323 Ferrochelatase [hemH]. 23 350 27.742 T 09-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 Pfam PF04962 KduI/IolB family 23 280 8.2E-90 T 09-03-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 Gene3D G3DSA:2.60.120.10 125 287 1.2E-65 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 SUPERFAMILY SSF51182 31 265 1.53E-57 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 PIRSF PIRSF036628 17 286 6.2E-87 T 09-03-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 Gene3D G3DSA:2.60.120.10 30 124 2.1E-26 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS14055 c7d4ca31c7390310ab17c3c63661b3d3 297 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 30 281 2.6E-83 T 09-03-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 SUPERFAMILY SSF51735 7 163 7.89E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 Gene3D G3DSA:3.30.360.10 142 362 1.6E-48 T 09-03-2017 ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 130 5.6E-24 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 143 208 3.7E-6 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 SUPERFAMILY SSF55347 139 333 7.03E-30 T 09-03-2017 ARZXY2_RS01285 6700dd971665e43ec93a7aaaf513fd98 367 Gene3D G3DSA:3.40.50.720 7 141 7.2E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 230 1.6E-11 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 Gene3D G3DSA:3.30.360.10 139 344 2.7E-34 T 09-03-2017 ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 SUPERFAMILY SSF55347 138 294 1.34E-27 T 09-03-2017 ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 Gene3D G3DSA:3.40.50.720 7 138 1.8E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 SUPERFAMILY SSF51735 5 165 4.48E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16090 888ee214541d339b9a923f6732cf4f8b 347 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 128 5.4E-14 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 127 140 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 176 191 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 260 280 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 337 351 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 317 333 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PRINTS PR00143 Citrate synthase signature 198 226 3.7E-36 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 8 378 7.4E-137 T 09-03-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 Pfam PF00285 Citrate synthase, C-terminal domain 9 366 3.8E-118 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 PIRSF PIRSF001369 1 379 1.0E-118 T 09-03-2017 IPR024176 Citrate synthase, bacterial-type ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 SUPERFAMILY SSF48256 6 378 8.5E-126 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 Gene3D G3DSA:1.10.580.10 6 274 6.5E-92 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 ARZXY2_RS11090 8ee025562a9c12b7562d9d29a0e7fdc3 379 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 09-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 ARZXY2_RS16875 56fc15b38fe4d0625b5df8f0850a903d 249 Pfam PF03746 LamB/YcsF family 1 238 4.0E-93 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF ARZXY2_RS16875 56fc15b38fe4d0625b5df8f0850a903d 249 SUPERFAMILY SSF88713 1 248 5.41E-91 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS16875 56fc15b38fe4d0625b5df8f0850a903d 249 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 243 41.073 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 72 81 7.9E-13 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 172 184 7.9E-13 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 194 206 7.9E-13 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 262 272 7.9E-13 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 132 144 7.9E-13 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 77 272 2.3E-78 T 09-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 Pfam PF00813 FliP family 77 268 7.4E-74 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 249 261 - T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 113 132 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 222 243 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 246 271 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 221 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 74 93 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS14455 430e803b50d91cb64c3a5002aa0989fc 275 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 93 113 7.6E-62 T 09-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 PIRSF PIRSF000362 8 483 1.5E-156 T 09-03-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 Gene3D G3DSA:3.50.50.60 111 339 3.9E-65 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 SUPERFAMILY SSF51971 332 453 2.47E-5 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 193 3.0E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 SUPERFAMILY SSF51971 280 340 3.65E-56 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 SUPERFAMILY SSF51971 13 226 3.65E-56 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 PRINTS PR00419 Adrenodoxin reductase family signature 15 37 4.5E-16 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 PRINTS PR00419 Adrenodoxin reductase family signature 89 99 4.5E-16 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 PRINTS PR00419 Adrenodoxin reductase family signature 160 174 4.5E-16 T 09-03-2017 ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 Gene3D G3DSA:3.40.50.720 13 110 9.3E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02920 8d476b5abbbeedaf1d91b86f5bb0712d 488 Gene3D G3DSA:3.40.50.720 340 479 9.3E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13520 38d263b89973079fcb2e203e58c6627a 225 SMART SM00382 27 213 8.1E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13520 38d263b89973079fcb2e203e58c6627a 225 SUPERFAMILY SSF52540 8 212 2.86E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13520 38d263b89973079fcb2e203e58c6627a 225 Gene3D G3DSA:3.40.50.300 3 211 1.7E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13520 38d263b89973079fcb2e203e58c6627a 225 Pfam PF00005 ABC transporter 18 167 4.8E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13520 38d263b89973079fcb2e203e58c6627a 225 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS19895 f2ee94f7a6b11405bba71c77787f630b 62 Pfam PF05532 CsbD-like 5 57 1.0E-16 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS19895 f2ee94f7a6b11405bba71c77787f630b 62 Gene3D G3DSA:1.10.1470.10 5 59 1.6E-13 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS19895 f2ee94f7a6b11405bba71c77787f630b 62 SUPERFAMILY SSF69047 4 59 1.23E-7 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 Gene3D G3DSA:3.90.650.10 163 335 1.4E-43 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 SUPERFAMILY SSF56042 160 311 5.86E-24 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 SUPERFAMILY SSF55326 10 154 9.59E-24 T 09-03-2017 ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 154 1.2E-15 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 13 335 1.6E-65 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 167 266 8.7E-8 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 PIRSF PIRSF005303 6 335 1.2E-68 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 ARZXY2_RS05785 98821242ec998d16e9b65f946934b653 337 Gene3D G3DSA:3.30.1330.10 7 155 1.2E-38 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Gene3D G3DSA:3.90.1200.10 252 419 4.8E-5 T 09-03-2017 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 590 1214 43.889 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SUPERFAMILY SSF56112 141 419 6.33E-18 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 598 1211 3.0E-282 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SUPERFAMILY SSF81296 606 715 3.5E-31 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SUPERFAMILY SSF81296 505 603 4.0E-16 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Gene3D G3DSA:2.60.40.10 602 715 7.0E-36 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Gene3D G3DSA:2.60.40.10 504 595 1.3E-14 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 1116 1212 3.5E-22 T 09-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 614 700 1.8E-21 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SUPERFAMILY SSF51011 1111 1213 6.84E-30 T 09-03-2017 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Pfam PF00128 Alpha amylase, catalytic domain 763 834 9.0E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SUPERFAMILY SSF51445 727 1108 9.27E-111 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 SMART SM00642 743 1084 5.0E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Gene3D G3DSA:3.20.20.80 737 1098 5.2E-92 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14830 b99b9ffa7133c793376f12f3fe622f9f 1215 Gene3D G3DSA:2.60.40.1180 1111 1212 5.4E-35 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta ARZXY2_RS05880 1f57b686e7fa8c5be7d865a86d968469 704 Pfam PF16565 Phospholipase D-like domain at C-terminus of MIT 555 701 1.2E-40 T 09-03-2017 IPR032341 MIT, C-terminal phospholipase D-like domain ARZXY2_RS05880 1f57b686e7fa8c5be7d865a86d968469 704 Pfam PF13337 Putative ATP-dependent Lon protease 25 477 4.2E-181 T 09-03-2017 IPR014061 Conserved hypothetical protein CHP02688 ARZXY2_RS05880 1f57b686e7fa8c5be7d865a86d968469 704 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 22 470 4.6E-187 T 09-03-2017 IPR014061 Conserved hypothetical protein CHP02688 ARZXY2_RS17200 8d097a83e5242d551dbc120ea60af291 371 SUPERFAMILY SSF55931 2 357 3.24E-85 T 09-03-2017 ARZXY2_RS17200 8d097a83e5242d551dbc120ea60af291 371 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 371 74.273 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS17200 8d097a83e5242d551dbc120ea60af291 371 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 285 1.8E-88 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS17200 8d097a83e5242d551dbc120ea60af291 371 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 270 3.3E-50 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS01865 fbf6c52b14af181182ce127b194b3762 231 SUPERFAMILY SSF55729 66 213 2.36E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS01865 fbf6c52b14af181182ce127b194b3762 231 Gene3D G3DSA:3.40.630.30 102 212 2.5E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03195 7bde9486d4e7f70a9f50eb04aa8f30a1 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 3.0E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03195 7bde9486d4e7f70a9f50eb04aa8f30a1 317 SUPERFAMILY SSF161098 81 305 7.85E-47 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03195 7bde9486d4e7f70a9f50eb04aa8f30a1 317 Gene3D G3DSA:1.10.3720.10 32 307 2.2E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 19 329 3.5E-54 T 09-03-2017 IPR011852 TRAP transporter solute receptor, TAXI family ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 SUPERFAMILY SSF53850 34 328 6.09E-52 T 09-03-2017 ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 Gene3D G3DSA:3.40.190.10 132 258 9.5E-31 T 09-03-2017 ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 Pfam PF16868 NMT1-like family 41 328 3.3E-43 T 09-03-2017 IPR011852 TRAP transporter solute receptor, TAXI family ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 Gene3D G3DSA:3.40.190.10 259 328 8.3E-25 T 09-03-2017 ARZXY2_RS15565 b615b510eb29a3ae52347c390a7f7b70 332 Gene3D G3DSA:3.40.190.10 35 116 8.3E-25 T 09-03-2017 ARZXY2_RS15195 c6ee37ea50ebdc64a7bd3424e17418a4 304 SUPERFAMILY SSF103481 208 285 5.23E-9 T 09-03-2017 ARZXY2_RS15195 c6ee37ea50ebdc64a7bd3424e17418a4 304 SUPERFAMILY SSF103481 39 138 1.15E-14 T 09-03-2017 ARZXY2_RS15195 c6ee37ea50ebdc64a7bd3424e17418a4 304 Pfam PF00892 EamA-like transporter family 147 282 1.2E-13 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS15195 c6ee37ea50ebdc64a7bd3424e17418a4 304 Pfam PF00892 EamA-like transporter family 7 134 1.2E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 4.1E-11 T 09-03-2017 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 4.1E-11 T 09-03-2017 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.1E-11 T 09-03-2017 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 4.1E-11 T 09-03-2017 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 298 4.5E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 SUPERFAMILY SSF51905 3 305 1.1E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 Gene3D G3DSA:3.50.50.60 259 307 2.3E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 Gene3D G3DSA:3.50.50.60 4 134 2.3E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 4.4E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.4E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 4.4E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 4.4E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 4.4E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS14630 29a03435943ed39b2c691c7eabcc92b9 331 Gene3D G3DSA:3.50.50.60 135 233 1.2E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15480 8811dcb57c0b4662481383facbd2ab19 443 Pfam PF00083 Sugar (and other) transporter 28 239 3.4E-19 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS15480 8811dcb57c0b4662481383facbd2ab19 443 Gene3D G3DSA:1.20.1250.20 251 434 1.3E-11 T 09-03-2017 ARZXY2_RS15480 8811dcb57c0b4662481383facbd2ab19 443 Gene3D G3DSA:1.20.1250.20 25 233 2.4E-22 T 09-03-2017 ARZXY2_RS15480 8811dcb57c0b4662481383facbd2ab19 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 138 163 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS15480 8811dcb57c0b4662481383facbd2ab19 443 SUPERFAMILY SSF103473 10 433 1.06E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS02155 ff69cc88cf806fe9dd82f113d0d4ec14 251 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 229 3.3E-47 T 09-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 ARZXY2_RS14380 4da42e94530f29439eae24174cecc35d 273 SMART SM00477 28 247 2.4E-15 T 09-03-2017 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 ARZXY2_RS14380 4da42e94530f29439eae24174cecc35d 273 Pfam PF01223 DNA/RNA non-specific endonuclease 24 245 2.7E-48 T 09-03-2017 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 ARZXY2_RS14380 4da42e94530f29439eae24174cecc35d 273 Gene3D G3DSA:3.40.570.10 13 245 2.2E-41 T 09-03-2017 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 ARZXY2_RS14380 4da42e94530f29439eae24174cecc35d 273 SUPERFAMILY SSF54060 21 240 1.24E-45 T 09-03-2017 ARZXY2_RS14380 4da42e94530f29439eae24174cecc35d 273 SMART SM00892 27 247 1.2E-54 T 09-03-2017 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 ARZXY2_RS17505 919eae5755876b3a9fbe58a7ae9f4a77 69 Pfam PF07311 Dodecin 5 68 9.4E-29 T 09-03-2017 IPR009923 Dodecin ARZXY2_RS17505 919eae5755876b3a9fbe58a7ae9f4a77 69 Gene3D G3DSA:3.30.1660.10 3 68 1.5E-33 T 09-03-2017 IPR025543 Dodecin-like ARZXY2_RS17505 919eae5755876b3a9fbe58a7ae9f4a77 69 SUPERFAMILY SSF89807 3 68 5.62E-25 T 09-03-2017 IPR009923 Dodecin ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 Gene3D G3DSA:3.10.20.30 247 350 1.1E-23 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 SUPERFAMILY SSF52343 132 255 1.83E-22 T 09-03-2017 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 274 342 3.8E-9 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 301 309 - T 09-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 Pfam PF00970 Oxidoreductase FAD-binding domain 51 137 4.2E-5 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 Gene3D G3DSA:3.40.50.80 139 246 1.9E-23 T 09-03-2017 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 Gene3D G3DSA:2.40.30.10 37 135 1.2E-31 T 09-03-2017 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 SUPERFAMILY SSF63380 37 134 4.0E-27 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 SUPERFAMILY SSF54292 242 352 3.67E-23 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 223 231 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 179 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 74 86 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 86 100 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 110 124 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 64 74 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS09580 43989b2167be9da7519ceb49fbf31b02 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 145 164 1.8E-31 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 611 706 5.0E-22 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 328 1.3E-18 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 SUPERFAMILY SSF52540 25 273 1.47E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Gene3D G3DSA:3.40.50.300 378 642 2.5E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Gene3D G3DSA:3.40.50.300 24 277 1.3E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 SMART SM00382 54 253 9.0E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 SMART SM00382 419 611 4.9E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Pfam PF00005 ABC transporter 411 561 3.9E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Pfam PF00005 ABC transporter 46 203 4.2E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 613 675 1.2E-16 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 255 320 3.6E-17 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS20105 6afa4d4093db1f26a327ecf63b4ca3ad 720 SUPERFAMILY SSF52540 383 633 4.36E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14265 426e64f094ca18568bd25f6f30cbc0b2 821 Pfam PF13625 Helicase conserved C-terminal domain 543 664 1.0E-33 T 09-03-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 102 459 9.4E-133 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 Pfam PF16360 GTP-binding GTPase Middle Region 207 293 1.2E-29 T 09-03-2017 IPR032305 GTP-binding protein, middle domain ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 PIRSF PIRSF006809 92 519 1.5E-152 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 Hamap MF_00900 GTPase HflX [hflX]. 120 489 46.573 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 Pfam PF01926 50S ribosome-binding GTPase 301 419 6.0E-20 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 Pfam PF13167 GTP-binding GTPase N-terminal 117 205 2.3E-32 T 09-03-2017 IPR025121 GTPase HflX, N-terminal ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 Gene3D G3DSA:3.40.50.300 299 461 3.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 368 386 5.5E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 301 321 5.5E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS11355 b2d82aedd063aaa431de74c35fa91393 520 SUPERFAMILY SSF52540 290 461 1.7E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15055 f4cc6e3b66e91992c779be8a50cdff5a 488 Pfam PF00324 Amino acid permease 24 459 2.2E-111 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS15055 f4cc6e3b66e91992c779be8a50cdff5a 488 PIRSF PIRSF006060 3 480 3.3E-71 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS15055 f4cc6e3b66e91992c779be8a50cdff5a 488 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS18575 1873caed0e7f69a84a39114e2b7904ca 45 Pfam PF00468 Ribosomal protein L34 3 45 1.0E-19 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18575 1873caed0e7f69a84a39114e2b7904ca 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 09-03-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS18575 1873caed0e7f69a84a39114e2b7904ca 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.357 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18575 1873caed0e7f69a84a39114e2b7904ca 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 2.5E-19 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18575 1873caed0e7f69a84a39114e2b7904ca 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 23 3.0E-5 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 Gene3D G3DSA:3.30.860.10 1 92 1.8E-39 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.663 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.7E-24 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.7E-24 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.7E-24 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 09-03-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 PIRSF PIRSF002144 1 93 2.7E-30 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.3E-46 T 09-03-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 SUPERFAMILY SSF54570 3 84 1.7E-33 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03515 629ef780c979709af0406f4964989eab 93 Pfam PF00203 Ribosomal protein S19 3 83 4.2E-35 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 SMART SM01005 264 395 4.7E-52 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 TIGRFAM TIGR00492 alr: alanine racemase 27 395 1.2E-93 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 52 62 - T 09-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 Pfam PF00842 Alanine racemase, C-terminal domain 264 394 2.4E-36 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 SUPERFAMILY SSF50621 259 398 2.3E-40 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 297 312 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 83 101 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 377 390 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 47 63 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 317 334 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 223 250 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 280 295 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 143 155 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 PRINTS PR00992 Alanine racemase signature 180 191 1.6E-63 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 Gene3D G3DSA:2.40.37.10 244 398 3.1E-51 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 Hamap MF_01201 Alanine racemase. 22 395 32.033 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 Pfam PF01168 Alanine racemase, N-terminal domain 29 250 9.8E-67 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 SUPERFAMILY SSF51419 29 265 1.29E-64 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS03820 88b9d0c1fd5005b5897d5331b0c11cb1 425 Gene3D G3DSA:3.20.20.10 31 243 2.4E-72 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 SUPERFAMILY SSF82866 305 505 2.49E-32 T 09-03-2017 ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 6 513 36.815 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 Gene3D G3DSA:1.20.1640.10 305 506 3.9E-22 T 09-03-2017 ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 Pfam PF02355 Protein export membrane protein 327 500 7.1E-10 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 43 499 3.9E-100 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 ARZXY2_RS07990 45f095fb304db316335550a8ec76d52b 589 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 276 491 5.5E-57 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial ARZXY2_RS01630 0264e551d6c420485b3ef415a2a79654 203 SUPERFAMILY SSF53448 9 198 2.71E-30 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01630 0264e551d6c420485b3ef415a2a79654 203 Pfam PF12804 MobA-like NTP transferase domain 11 174 8.8E-36 T 09-03-2017 IPR025877 MobA-like NTP transferase ARZXY2_RS01630 0264e551d6c420485b3ef415a2a79654 203 Gene3D G3DSA:3.90.550.10 7 202 4.7E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Gene3D G3DSA:3.40.50.300 22 174 5.8E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Gene3D G3DSA:1.10.10.10 259 329 1.5E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 SMART SM00382 53 186 3.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Gene3D G3DSA:1.10.8.60 185 257 6.6E-28 T 09-03-2017 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 5.1E-29 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 SUPERFAMILY SSF52540 22 253 1.16E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 335 6.0E-28 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 358 151.822 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 236 1.6E-104 T 09-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 4.6E-131 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS07980 f28020c53e975d747028ec82af1710f5 358 SUPERFAMILY SSF46785 259 332 3.36E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 SMART SM00382 28 217 1.8E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 Gene3D G3DSA:3.40.50.300 4 239 1.3E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 SUPERFAMILY SSF52540 4 249 2.05E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 SUPERFAMILY SSF50331 244 359 2.88E-14 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS17100 2779b904d1a00462f30039ea82331d59 388 Pfam PF00005 ABC transporter 19 167 1.7E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS16670 2dab41ecd8c10991a7ffd67ea58e01aa 454 Pfam PF13416 Bacterial extracellular solute-binding protein 71 389 1.2E-40 T 09-03-2017 ARZXY2_RS16670 2dab41ecd8c10991a7ffd67ea58e01aa 454 SUPERFAMILY SSF53850 69 438 1.09E-62 T 09-03-2017 ARZXY2_RS16670 2dab41ecd8c10991a7ffd67ea58e01aa 454 Gene3D G3DSA:3.40.190.10 54 240 6.8E-38 T 09-03-2017 ARZXY2_RS18970 85ed61fb6fdd9c64b0b2fdb28edc476e 200 Pfam PF01380 SIS domain 49 162 4.8E-14 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS18970 85ed61fb6fdd9c64b0b2fdb28edc476e 200 Gene3D G3DSA:3.40.50.10490 28 199 1.5E-38 T 09-03-2017 ARZXY2_RS18970 85ed61fb6fdd9c64b0b2fdb28edc476e 200 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 24 200 3.1E-64 T 09-03-2017 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 ARZXY2_RS18970 85ed61fb6fdd9c64b0b2fdb28edc476e 200 SUPERFAMILY SSF53697 21 199 1.03E-34 T 09-03-2017 ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 SMART SM00849 12 192 4.8E-27 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 Gene3D G3DSA:3.40.250.10 365 459 1.9E-21 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 SUPERFAMILY SSF52821 235 359 1.17E-10 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 SUPERFAMILY SSF56281 1 259 7.14E-48 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 SUPERFAMILY SSF52821 367 458 1.05E-23 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 Gene3D G3DSA:3.40.250.10 267 356 1.7E-7 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 Gene3D G3DSA:3.60.15.10 4 256 8.1E-54 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 SMART SM00450 368 462 8.5E-11 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 Pfam PF00753 Metallo-beta-lactamase superfamily 13 187 2.3E-11 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00145 e9f06c29a692fa546935c743c142ef80 466 Pfam PF00581 Rhodanese-like domain 382 457 2.4E-11 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS10575 f1047a0d442129162a2f1925eeebb61b 234 SUPERFAMILY SSF52540 2 138 3.09E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10575 f1047a0d442129162a2f1925eeebb61b 234 Gene3D G3DSA:3.30.60.20 144 200 9.0E-5 T 09-03-2017 ARZXY2_RS10575 f1047a0d442129162a2f1925eeebb61b 234 Pfam PF00265 Thymidine kinase 3 198 1.1E-21 T 09-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 ARZXY2_RS10575 f1047a0d442129162a2f1925eeebb61b 234 PIRSF PIRSF035805 1 209 3.8E-35 T 09-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 ARZXY2_RS10575 f1047a0d442129162a2f1925eeebb61b 234 SUPERFAMILY SSF57716 144 202 2.52E-8 T 09-03-2017 ARZXY2_RS02605 ae6ac223f51e7a2c177ca072c3123a4a 296 SUPERFAMILY SSF52540 57 254 2.18E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02605 ae6ac223f51e7a2c177ca072c3123a4a 296 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02605 ae6ac223f51e7a2c177ca072c3123a4a 296 Gene3D G3DSA:3.40.50.300 57 276 6.8E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02605 ae6ac223f51e7a2c177ca072c3123a4a 296 Pfam PF00005 ABC transporter 62 192 4.7E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02605 ae6ac223f51e7a2c177ca072c3123a4a 296 SMART SM00382 69 240 2.9E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 SUPERFAMILY SSF50447 6 214 5.74E-81 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 Gene3D G3DSA:4.10.960.10 82 163 1.6E-34 T 09-03-2017 ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 Pfam PF00297 Ribosomal protein L3 102 186 2.7E-17 T 09-03-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 7 213 38.874 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 Gene3D G3DSA:2.40.30.10 9 38 4.3E-12 T 09-03-2017 ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 Gene3D G3DSA:2.40.30.10 164 214 4.3E-12 T 09-03-2017 ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 107 130 - T 09-03-2017 IPR019926 Ribosomal protein L3, conserved site ARZXY2_RS03495 8efdbf8b70ee3f837d7ece24efd4d1f8 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 9 210 6.2E-87 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Gene3D G3DSA:2.40.50.140 200 336 3.2E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 330 1.4E-15 T 09-03-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 SUPERFAMILY SSF56091 6 191 1.15E-40 T 09-03-2017 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Pfam PF01068 ATP dependent DNA ligase domain 11 197 2.3E-36 T 09-03-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Gene3D G3DSA:3.30.470.30 32 149 1.4E-28 T 09-03-2017 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 SUPERFAMILY SSF50249 200 339 1.63E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Gene3D G3DSA:3.30.1490.70 3 31 1.9E-8 T 09-03-2017 ARZXY2_RS20170 197f53ae4fb3f2c1cc4713aed43dca4f 355 Gene3D G3DSA:3.30.1490.70 156 197 1.9E-8 T 09-03-2017 ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 Pfam PF13242 HAD-hyrolase-like 99 167 2.7E-13 T 09-03-2017 ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 SUPERFAMILY SSF56784 6 172 1.77E-43 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 145 1.3E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 8 146 6.7E-32 T 09-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 Gene3D G3DSA:3.40.50.1000 7 172 1.6E-47 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18115 a0f402aab9e502da20721406511c9e4c 199 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 8 146 4.9E-31 T 09-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 ARZXY2_RS20115 94fcfb58df37e1fc1d2ae312c6981a39 59 Gene3D G3DSA:3.40.1620.10 4 39 7.0E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS20115 94fcfb58df37e1fc1d2ae312c6981a39 59 SUPERFAMILY SSF143120 4 46 3.01E-5 T 09-03-2017 ARZXY2_RS20115 94fcfb58df37e1fc1d2ae312c6981a39 59 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 50 9.3E-7 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS20115 94fcfb58df37e1fc1d2ae312c6981a39 59 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 41 7.0E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS14310 809c0a82ce68de352ae986803cbe6aa2 96 SUPERFAMILY SSF140453 2 94 4.19E-18 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS14310 809c0a82ce68de352ae986803cbe6aa2 96 Pfam PF06013 Proteins of 100 residues with WXG 4 88 2.2E-17 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS14310 809c0a82ce68de352ae986803cbe6aa2 96 Gene3D G3DSA:1.10.287.1060 3 95 6.2E-20 T 09-03-2017 ARZXY2_RS14310 809c0a82ce68de352ae986803cbe6aa2 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 6.6E-18 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 9.5E-15 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 9.5E-15 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 9.5E-15 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 9.5E-15 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 9.5E-15 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00370 a7284d466ae81f0de4b5fb28361c0c94 522 Pfam PF00361 Proton-conducting membrane transporter 133 420 3.1E-67 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 PIRSF PIRSF005496 10 877 2.1E-249 T 09-03-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 SUPERFAMILY SSF52540 216 378 1.03E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 SUPERFAMILY SSF52540 26 176 1.03E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Gene3D G3DSA:3.40.50.300 250 380 4.3E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 SMART SM00487 10 213 6.2E-17 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Pfam PF08482 ATP-dependent helicase C-terminal 724 864 3.3E-50 T 09-03-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Pfam PF00270 DEAD/DEAH box helicase 24 176 3.5E-9 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 SMART SM00847 429 521 2.3E-11 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Gene3D G3DSA:3.40.50.300 26 175 4.5E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 SMART SM00490 266 369 8.7E-14 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Pfam PF04408 Helicase associated domain (HA2) 430 487 2.2E-9 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 20 876 8.6E-196 T 09-03-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type ARZXY2_RS09290 f6298279f9bf875ce8aec84709d112cb 877 Pfam PF00271 Helicase conserved C-terminal domain 250 369 2.1E-10 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 Pfam PF00571 CBS domain 222 270 7.9E-7 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 Pfam PF01595 Domain of unknown function DUF21 10 200 6.2E-41 T 09-03-2017 IPR002550 Domain of unknown function DUF21 ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 Gene3D G3DSA:3.10.580.10 208 343 2.6E-17 T 09-03-2017 ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 SUPERFAMILY SSF54631 206 343 1.46E-23 T 09-03-2017 ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 SMART SM00116 287 335 0.48 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS05065 f4d7ca04b4632f2534e62e6fa56d30dd 357 SMART SM00116 225 273 0.0078 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 Gene3D G3DSA:3.30.360.10 181 459 7.6E-79 T 09-03-2017 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 7 462 65.39 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 320 346 4.6E-37 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 231 247 4.6E-37 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 213 230 4.6E-37 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 189 4.6E-37 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 137 150 4.6E-37 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 SUPERFAMILY SSF51735 8 183 2.36E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 PIRSF PIRSF000110 1 470 5.6E-115 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 Gene3D G3DSA:3.40.50.720 9 180 1.6E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 185 459 5.2E-68 T 09-03-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 SUPERFAMILY SSF55347 171 461 3.07E-76 T 09-03-2017 ARZXY2_RS06970 a10fbb1091ff56ce0d71966bddb05ca4 472 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 12 181 7.4E-34 T 09-03-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 SMART SM00490 268 349 8.3E-23 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 33 366 1.0E-66 T 09-03-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Gene3D G3DSA:3.40.50.2020 576 718 4.6E-7 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Gene3D G3DSA:1.10.10.10 373 433 3.9E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Gene3D G3DSA:3.40.50.300 31 215 8.9E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 SUPERFAMILY SSF52540 80 369 5.33E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Gene3D G3DSA:3.40.50.300 225 369 2.5E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 SMART SM00487 31 229 7.4E-25 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Pfam PF00271 Helicase conserved C-terminal domain 252 348 4.4E-13 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 SUPERFAMILY SSF53271 570 718 5.51E-9 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Gene3D G3DSA:1.10.10.10 447 504 9.1E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 Pfam PF00270 DEAD/DEAH box helicase 38 207 2.1E-17 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS15080 8a4b089edbc87340d06330ec49d74c1f 721 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 157 166 - T 09-03-2017 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 Gene3D G3DSA:3.50.50.60 127 236 3.9E-34 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 Gene3D G3DSA:3.50.50.60 237 308 9.0E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 Gene3D G3DSA:3.50.50.60 12 125 4.0E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 13 313 1.8E-117 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 302 7.5E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.2E-36 T 09-03-2017 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 1.2E-36 T 09-03-2017 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 1.2E-36 T 09-03-2017 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.2E-36 T 09-03-2017 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.2E-36 T 09-03-2017 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 143 163 - T 09-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 47 62 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 6.2E-78 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS06680 d56504a37772c7d27edbbfe9aec48bc0 333 SUPERFAMILY SSF51905 13 312 5.4E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 Gene3D G3DSA:3.40.50.720 107 295 1.5E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 SUPERFAMILY SSF52283 29 125 2.98E-11 T 09-03-2017 ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 SUPERFAMILY SSF51735 97 292 4.7E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 323 8.0E-9 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 291 6.2E-39 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS19260 5f935658818584e76fed709f238c9618 336 Gene3D G3DSA:3.40.50.720 1 106 4.4E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 Gene3D G3DSA:3.50.50.60 8 76 1.6E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 Gene3D G3DSA:3.50.50.60 151 331 1.6E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 SUPERFAMILY SSF51905 8 306 2.56E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 6 493 51.651 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 10 490 3.1E-229 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 ARZXY2_RS05575 864159a62d0856f5295c3c951987760a 501 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 9 493 6.9E-230 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 Gene3D G3DSA:1.10.10.10 3 67 2.4E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 SMART SM00895 96 218 7.5E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 SUPERFAMILY SSF46785 3 70 1.15E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 SUPERFAMILY SSF48008 95 218 2.62E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 SMART SM00345 8 66 4.3E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 Pfam PF07729 FCD domain 96 216 2.0E-22 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 Gene3D G3DSA:1.20.120.530 94 223 5.9E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS17340 1e155678cd392b37f6d351ef259aa314 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 3.1E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 Gene3D G3DSA:3.40.190.10 2 88 2.5E-27 T 09-03-2017 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 SUPERFAMILY SSF53850 4 185 9.99E-54 T 09-03-2017 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 Gene3D G3DSA:3.40.190.10 89 167 3.9E-19 T 09-03-2017 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 155 177 - T 09-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 Pfam PF00800 Prephenate dehydratase 5 180 3.0E-47 T 09-03-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 SUPERFAMILY SSF55021 174 274 1.94E-23 T 09-03-2017 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 PIRSF PIRSF001500 1 277 3.3E-54 T 09-03-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 ARZXY2_RS00585 6ad074a3fd33cc01a74a3d99fdf662b8 292 Gene3D G3DSA:3.30.70.260 191 275 4.5E-25 T 09-03-2017 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Gene3D G3DSA:3.40.710.10 336 538 6.0E-59 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Gene3D G3DSA:3.40.710.10 572 661 6.0E-59 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 ProSitePatterns PS00337 Beta-lactamase class-D active site. 383 393 - T 09-03-2017 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 SUPERFAMILY SSF54427 61 133 7.71E-7 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 656 1.4E-37 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Gene3D G3DSA:3.90.1310.10 242 335 2.7E-12 T 09-03-2017 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 30 134 3.9E-8 T 09-03-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 Pfam PF03717 Penicillin-binding Protein dimerisation domain 142 300 8.8E-17 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 SUPERFAMILY SSF56601 277 544 2.72E-59 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 SUPERFAMILY SSF56601 571 661 2.72E-59 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18685 b40b4633518daae97c67956004aa6d42 662 SUPERFAMILY SSF56519 138 329 1.31E-20 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 ARZXY2_RS17020 da61e8c5cabd034ee271617320e78010 175 Pfam PF12728 Helix-turn-helix domain 85 133 1.1E-11 T 09-03-2017 ARZXY2_RS17020 da61e8c5cabd034ee271617320e78010 175 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 84 130 6.4E-15 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS17020 da61e8c5cabd034ee271617320e78010 175 SUPERFAMILY SSF46955 83 136 1.56E-6 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS18940 90827eee5cf3c05cbcd03be6ea86390b 338 Pfam PF00892 EamA-like transporter family 162 305 8.9E-14 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18940 90827eee5cf3c05cbcd03be6ea86390b 338 Pfam PF00892 EamA-like transporter family 17 151 1.3E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18940 90827eee5cf3c05cbcd03be6ea86390b 338 SUPERFAMILY SSF103481 223 308 3.66E-13 T 09-03-2017 ARZXY2_RS18940 90827eee5cf3c05cbcd03be6ea86390b 338 SUPERFAMILY SSF103481 58 151 7.85E-12 T 09-03-2017 ARZXY2_RS12890 6184aa8d9efe8aa1795f8633904a5663 172 Pfam PF06262 Zinicin-like metallopeptidase 87 165 6.9E-8 T 09-03-2017 IPR010428 Zinicin-like metallopeptidase ARZXY2_RS12890 6184aa8d9efe8aa1795f8633904a5663 172 SUPERFAMILY SSF55486 58 167 4.39E-26 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 484 47.631 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SUPERFAMILY SSF51735 240 406 5.74E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 PIRSF PIRSF001109 1 492 3.9E-186 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SUPERFAMILY SSF52283 407 492 3.0E-111 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SUPERFAMILY SSF52283 192 239 3.0E-111 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SUPERFAMILY SSF52283 2 154 3.0E-111 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 5 484 8.3E-188 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Gene3D G3DSA:3.40.50.720 242 405 4.6E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 76 90 - T 09-03-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SMART SM00996 4 491 0.0 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 262 278 - T 09-03-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 4 491 9.5E-147 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 SMART SM00997 240 406 1.5E-103 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Gene3D G3DSA:3.40.50.1480 4 241 3.3E-144 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Gene3D G3DSA:3.40.50.1480 407 492 3.3E-144 T 09-03-2017 ARZXY2_RS12875 cdc8375b7e3cdf49ae51655010e68259 492 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 240 406 5.5E-77 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 ARZXY2_RS09285 c6d1d046088cc51aadeb8f475d1cc75d 245 Pfam PF13398 Peptidase M50B-like 32 229 4.4E-42 T 09-03-2017 ARZXY2_RS00290 017a88a473869844d5122720e5da0efc 257 SUPERFAMILY SSF51658 10 239 4.58E-27 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00290 017a88a473869844d5122720e5da0efc 257 Gene3D G3DSA:3.20.20.150 13 252 3.7E-34 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00290 017a88a473869844d5122720e5da0efc 257 Pfam PF01261 Xylose isomerase-like TIM barrel 29 169 2.1E-18 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 Gene3D G3DSA:3.50.50.60 213 292 1.4E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 Gene3D G3DSA:3.50.50.60 1 98 1.4E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 Pfam PF01593 Flavin containing amine oxidoreductase 7 445 3.0E-26 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 467 2.3E-38 T 09-03-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 SUPERFAMILY SSF54373 302 418 4.71E-10 T 09-03-2017 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 Gene3D G3DSA:1.10.3110.10 101 199 6.5E-11 T 09-03-2017 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 SUPERFAMILY SSF51905 436 467 4.75E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04465 f57103db331bac8ddffa4a3807ae1987 474 SUPERFAMILY SSF51905 1 316 4.75E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 SMART SM00448 5 113 9.0E-22 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 Gene3D G3DSA:1.10.10.10 158 200 1.9E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 Pfam PF00072 Response regulator receiver domain 7 113 3.8E-17 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 Gene3D G3DSA:3.40.50.2300 4 125 2.7E-24 T 09-03-2017 ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 155 202 4.2E-8 T 09-03-2017 IPR002831 Transcription regulator TrmB, N-terminal ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 SUPERFAMILY SSF52172 4 157 7.54E-29 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 PIRSF PIRSF006171 3 219 3.3E-62 T 09-03-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 ARZXY2_RS12370 868d28265d53f2f955f315b3f6ca6cd4 219 SUPERFAMILY SSF46785 155 217 7.52E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16895 ae92064273339778e45c86c2527eaa51 375 SUPERFAMILY SSF54506 170 357 3.3E-45 T 09-03-2017 ARZXY2_RS16895 ae92064273339778e45c86c2527eaa51 375 Pfam PF04303 PrpF protein 1 354 1.4E-87 T 09-03-2017 IPR007400 PrpF protein ARZXY2_RS16895 ae92064273339778e45c86c2527eaa51 375 Gene3D G3DSA:3.10.310.10 1 174 6.4E-61 T 09-03-2017 ARZXY2_RS16895 ae92064273339778e45c86c2527eaa51 375 SUPERFAMILY SSF54506 2 166 1.18E-47 T 09-03-2017 ARZXY2_RS16895 ae92064273339778e45c86c2527eaa51 375 Gene3D G3DSA:3.10.310.10 175 333 9.5E-48 T 09-03-2017 ARZXY2_RS15125 7b64c4458492de98b420d4834d10b0be 292 Pfam PF00665 Integrase core domain 142 252 6.9E-19 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS15125 7b64c4458492de98b420d4834d10b0be 292 SUPERFAMILY SSF46689 4 122 7.35E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS15125 7b64c4458492de98b420d4834d10b0be 292 Gene3D G3DSA:3.30.420.10 138 253 1.8E-23 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS15125 7b64c4458492de98b420d4834d10b0be 292 SUPERFAMILY SSF53098 138 253 2.28E-19 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 Gene3D G3DSA:2.40.50.100 289 354 6.9E-16 T 09-03-2017 ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 Gene3D G3DSA:3.40.50.300 15 232 4.2E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 SUPERFAMILY SSF50331 236 352 2.84E-17 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 SUPERFAMILY SSF52540 13 235 1.46E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 Pfam PF03459 TOBE domain 291 350 2.7E-14 T 09-03-2017 IPR005116 Transport-associated OB, type 1 ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 SMART SM00382 22 211 1.1E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01080 04584cf740fd42711b7251fc7e94d32e 356 Pfam PF00005 ABC transporter 15 164 5.3E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 Gene3D G3DSA:3.40.50.450 1 206 4.1E-73 T 09-03-2017 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 SUPERFAMILY SSF53784 1 331 3.27E-114 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 Pfam PF00365 Phosphofructokinase 2 295 6.3E-97 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PIRSF PIRSF000532 1 339 2.3E-114 T 09-03-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 40.422 T 09-03-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.7E-71 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 1.8E-139 T 09-03-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 ARZXY2_RS03360 312f09c71289dfd1ee259648654a6098 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 09-03-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS13245 1014b5f295333408a5688affeaba3914 225 Gene3D G3DSA:3.90.1140.10 46 213 3.2E-19 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase ARZXY2_RS13245 1014b5f295333408a5688affeaba3914 225 SUPERFAMILY SSF55144 41 204 2.88E-29 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase ARZXY2_RS13245 1014b5f295333408a5688affeaba3914 225 Pfam PF13563 2'-5' RNA ligase superfamily 46 190 1.2E-22 T 09-03-2017 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 Gene3D G3DSA:2.30.33.40 4 96 2.9E-37 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 25.707 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 PRINTS PR00297 10kDa chaperonin signature 27 48 4.3E-31 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 PRINTS PR00297 10kDa chaperonin signature 5 20 4.3E-31 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 PRINTS PR00297 10kDa chaperonin signature 62 74 4.3E-31 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 PRINTS PR00297 10kDa chaperonin signature 83 96 4.3E-31 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 09-03-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 SMART SM00883 4 96 1.4E-53 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 SUPERFAMILY SSF50129 3 96 9.23E-34 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS03875 f4f3ed48a47d2d848e8955191e9d9460 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 96 5.0E-34 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 Pfam PF01799 [2Fe-2S] binding domain 87 160 6.1E-25 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 20 84 5.6E-7 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 Gene3D G3DSA:3.10.20.30 15 88 6.5E-21 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 SUPERFAMILY SSF47741 99 168 2.36E-27 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 Gene3D G3DSA:1.10.150.120 89 173 1.6E-30 T 09-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 ARZXY2_RS09605 43187a1fc10591bd5e4418d99c1171b4 177 SUPERFAMILY SSF54292 15 92 3.93E-20 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 SMART SM00450 153 270 2.0E-12 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 SMART SM00450 6 131 7.7E-28 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 Gene3D G3DSA:3.40.250.10 2 143 6.2E-45 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 Gene3D G3DSA:3.40.250.10 153 278 2.6E-34 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 SUPERFAMILY SSF52821 151 278 4.71E-30 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 Pfam PF00581 Rhodanese-like domain 165 266 1.7E-9 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 Pfam PF00581 Rhodanese-like domain 7 127 4.5E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 SUPERFAMILY SSF52821 4 138 5.76E-40 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05100 40636a024bf5b410772d2fdf9088868f 297 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.485 T 09-03-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 3.1E-22 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 PRINTS PR01249 Ribosomal protein L31 signature 60 78 8.8E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 PRINTS PR01249 Ribosomal protein L31 signature 2 19 8.8E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 PRINTS PR01249 Ribosomal protein L31 signature 45 60 8.8E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 Pfam PF01197 Ribosomal protein L31 1 79 8.5E-30 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08880 0786ca0765516681a1e73f9ad2f20d92 85 SUPERFAMILY SSF143800 1 81 1.18E-22 T 09-03-2017 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 Pfam PF02734 DAK2 domain 390 561 5.0E-47 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 Gene3D G3DSA:3.30.1180.20 183 330 2.7E-48 T 09-03-2017 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 367 561 2.9E-43 T 09-03-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 Pfam PF02733 Dak1 domain 18 326 5.4E-106 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 Gene3D G3DSA:3.40.50.10440 13 180 3.4E-56 T 09-03-2017 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 SUPERFAMILY SSF82549 11 329 2.62E-105 T 09-03-2017 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 SUPERFAMILY SSF101473 365 564 5.23E-46 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS13815 baf6add1785130d13b5ca2884549a004 583 SMART SM01120 389 563 4.3E-59 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS14515 11b416c45333258cc82382bd4f4382ed 207 Pfam PF00877 NlpC/P60 family 99 194 7.0E-21 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS14515 11b416c45333258cc82382bd4f4382ed 207 SUPERFAMILY SSF54001 83 201 1.52E-32 T 09-03-2017 ARZXY2_RS14515 11b416c45333258cc82382bd4f4382ed 207 Gene3D G3DSA:3.90.1720.10 83 202 1.3E-36 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS10420 778d07267a7ac7451e9db8f0baad3773 414 TIGRFAM TIGR00843 benE: benzoate transporter 19 392 2.9E-75 T 09-03-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 ARZXY2_RS10420 778d07267a7ac7451e9db8f0baad3773 414 Pfam PF03594 Benzoate membrane transport protein 21 392 9.4E-97 T 09-03-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 ARZXY2_RS04425 39c9d940e2cf53449c79e7bf16913c97 78 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 78 4.9E-18 T 09-03-2017 IPR010035 ThiS, thiamine-biosynthesis ARZXY2_RS04425 39c9d940e2cf53449c79e7bf16913c97 78 Gene3D G3DSA:3.10.20.30 1 78 1.6E-24 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS04425 39c9d940e2cf53449c79e7bf16913c97 78 SUPERFAMILY SSF54285 1 78 6.21E-14 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp ARZXY2_RS04425 39c9d940e2cf53449c79e7bf16913c97 78 Pfam PF02597 ThiS family 5 78 1.7E-12 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 SUPERFAMILY SSF52540 197 398 4.44E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 125 398 1.3E-102 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 372 385 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 Pfam PF00448 SRP54-type protein, GTPase domain 199 398 7.0E-73 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 Gene3D G3DSA:1.20.120.140 126 210 6.4E-27 T 09-03-2017 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 SUPERFAMILY SSF47364 97 176 1.31E-18 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 SMART SM00963 102 182 2.1E-21 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 125 399 58.329 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 Pfam PF02881 SRP54-type protein, helical bundle domain 113 178 2.1E-12 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 SMART SM00382 198 349 2.7E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 SMART SM00962 199 399 5.1E-104 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 ARZXY2_RS06950 61ab1d5732352724642151e5a5857f5c 399 Gene3D G3DSA:3.40.50.300 211 398 7.8E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 SUPERFAMILY SSF55811 12 146 2.17E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 157 255 7.8E-14 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 Pfam PF00293 NUDIX domain 21 129 3.8E-17 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 SUPERFAMILY SSF53254 157 273 4.28E-17 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 Gene3D G3DSA:3.40.50.1240 157 278 6.5E-20 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 SMART SM00855 156 270 8.2E-7 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 PRINTS PR00502 NUDIX hydrolase family signature 48 62 1.3E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 PRINTS PR00502 NUDIX hydrolase family signature 62 77 1.3E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS03300 cde98598cf7173d2551cab4d63b72388 322 Gene3D G3DSA:3.90.79.10 20 144 7.9E-32 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS00560 7ef0aa3f37e68d1271a9cad18b49cfb2 188 SMART SM00347 46 150 4.7E-4 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS00560 7ef0aa3f37e68d1271a9cad18b49cfb2 188 Pfam PF12802 MarR family 53 114 1.4E-6 T 09-03-2017 ARZXY2_RS00560 7ef0aa3f37e68d1271a9cad18b49cfb2 188 Gene3D G3DSA:1.10.10.10 26 162 1.3E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00560 7ef0aa3f37e68d1271a9cad18b49cfb2 188 SUPERFAMILY SSF46785 26 164 3.14E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 Pfam PF13377 Periplasmic binding protein-like domain 176 334 5.8E-33 T 09-03-2017 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 Gene3D G3DSA:3.40.50.2300 62 182 4.1E-36 T 09-03-2017 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 56 9.6E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 SMART SM00354 9 79 1.1E-26 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 Gene3D G3DSA:1.10.260.40 11 61 3.7E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 SUPERFAMILY SSF53822 69 338 1.01E-57 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 SUPERFAMILY SSF47413 8 67 2.41E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 Gene3D G3DSA:3.40.50.2300 183 312 2.9E-41 T 09-03-2017 ARZXY2_RS01960 0e7a952da4f0b536f79460b1a7013e0c 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 09-03-2017 ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 23 315 28.865 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 SUPERFAMILY SSF55060 192 314 1.22E-19 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 Pfam PF08544 GHMP kinases C terminal 234 308 4.7E-7 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 SUPERFAMILY SSF54211 22 184 2.58E-39 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 Gene3D G3DSA:3.30.230.10 24 185 1.1E-47 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 PIRSF PIRSF010376 21 323 1.7E-68 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 22 302 6.1E-48 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 Gene3D G3DSA:3.30.70.890 192 316 5.3E-23 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS12800 50f2d12eceaf2b56b10d737361082323 330 Pfam PF00288 GHMP kinases N terminal domain 114 172 1.8E-10 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Pfam PF11798 IMS family HHH motif 169 198 3.7E-6 T 09-03-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 346 2.3E-19 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Gene3D G3DSA:1.10.150.20 166 239 2.2E-20 T 09-03-2017 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 SUPERFAMILY SSF100879 240 338 7.65E-27 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Gene3D G3DSA:3.30.70.270 67 164 6.2E-28 T 09-03-2017 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Pfam PF00817 impB/mucB/samB family 9 154 9.2E-47 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Hamap MF_01113 DNA polymerase IV [dinB]. 3 353 35.642 T 09-03-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 SUPERFAMILY SSF56672 5 235 2.4E-78 T 09-03-2017 ARZXY2_RS10900 114bfac5d1b378a246d9b854bad28590 394 Gene3D G3DSA:3.30.1490.100 242 349 4.6E-32 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 Gene3D G3DSA:3.90.550.10 9 250 3.2E-65 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 SUPERFAMILY SSF53448 11 249 2.5E-50 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 248 1.8E-59 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 112 119 - T 09-03-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 250 4.8E-60 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ARZXY2_RS14895 2c4e1c93e6db3bc56ea167517361cd54 260 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 252 27.206 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Gene3D G3DSA:3.20.20.70 466 805 1.3E-101 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Gene3D G3DSA:3.60.20.10 44 465 2.9E-180 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Gene3D G3DSA:2.160.20.60 1250 1520 2.1E-93 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 SUPERFAMILY SSF51395 470 1230 2.2E-257 T 09-03-2017 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Pfam PF01645 Conserved region in glutamate synthase 831 1196 2.6E-153 T 09-03-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Pfam PF01493 GXGXG motif 1276 1452 4.1E-72 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Pfam PF00310 Glutamine amidotransferases class-II 44 455 3.3E-173 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 SUPERFAMILY SSF69336 1245 1511 7.19E-85 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Gene3D G3DSA:3.20.20.70 880 1230 5.6E-175 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 SUPERFAMILY SSF56235 44 459 1.25E-144 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS10250 6a182064cff13882f66aef9c4b8156da 1537 Pfam PF04898 Glutamate synthase central domain 482 767 4.9E-107 T 09-03-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 SUPERFAMILY SSF51230 531 604 5.5E-20 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 SUPERFAMILY SSF56059 94 338 4.42E-58 T 09-03-2017 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Pfam PF00289 Biotin carboxylase, N-terminal domain 13 121 8.7E-44 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Gene3D G3DSA:3.40.50.20 13 140 3.6E-50 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 SUPERFAMILY SSF51246 340 456 1.26E-35 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 560 577 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Gene3D G3DSA:3.30.1490.20 141 213 1.3E-24 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Gene3D G3DSA:2.40.50.100 535 604 7.7E-22 T 09-03-2017 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 SUPERFAMILY SSF52440 11 124 4.24E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Pfam PF02785 Biotin carboxylase C-terminal domain 345 455 7.8E-36 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 SMART SM00878 345 455 1.9E-55 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Pfam PF00364 Biotin-requiring enzyme 538 603 1.0E-16 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Gene3D G3DSA:3.30.470.20 215 458 4.5E-86 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS12525 4ab009581f65a36c2c0b90f90fb71c00 605 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 126 332 6.4E-75 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 SUPERFAMILY SSF88713 254 519 7.12E-79 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 Gene3D G3DSA:1.20.1270.50 524 625 1.2E-24 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 Gene3D G3DSA:3.20.110.10 205 523 7.5E-88 T 09-03-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 663 1020 6.0E-55 T 09-03-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 Pfam PF09261 Alpha mannosidase middle domain 521 601 9.5E-29 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 SMART SM00872 521 601 4.8E-38 T 09-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 SUPERFAMILY SSF74650 668 983 1.35E-55 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 259 512 1.0E-84 T 09-03-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 ARZXY2_RS14200 b4910c7612437fb49a4d3836d5c1b68d 1023 SUPERFAMILY SSF88688 520 628 3.92E-28 T 09-03-2017 IPR028995 Glycoside hydrolase families 57/38, central domain ARZXY2_RS02980 d88c4bee93c4b8ee2a838081f5182847 510 PIRSF PIRSF006060 4 499 1.1E-90 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS02980 d88c4bee93c4b8ee2a838081f5182847 510 Pfam PF13520 Amino acid permease 27 460 2.5E-55 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 Pfam PF13185 GAF domain 69 162 8.1E-9 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 SUPERFAMILY SSF52172 160 231 1.64E-7 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 Gene3D G3DSA:1.10.10.10 179 235 3.2E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 Pfam PF03861 ANTAR domain 179 231 3.7E-16 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 SUPERFAMILY SSF55781 58 176 2.12E-15 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 SMART SM01012 176 231 6.7E-19 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS13620 eed2b6d671b5c66d0724bac82bb4026c 245 Gene3D G3DSA:3.30.450.40 64 165 2.6E-12 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 Gene3D G3DSA:3.20.20.70 4 207 5.4E-75 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 Pfam PF01081 KDPG and KHG aldolase 4 196 3.9E-67 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 SUPERFAMILY SSF51569 4 205 1.36E-65 T 09-03-2017 ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 35 44 - T 09-03-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 09-03-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS00810 c16c4b92f658a517eff0fab65c2b339b 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 4 204 3.4E-76 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS18380 1a6779a4a1834d80c1c3da649223f05f 493 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 205 304 1.8E-6 T 09-03-2017 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain ARZXY2_RS18380 1a6779a4a1834d80c1c3da649223f05f 493 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 192 315 3.7E-15 T 09-03-2017 IPR026466 Fimbrial isopeptide formation D2 domain ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 SUPERFAMILY SSF54713 181 277 3.43E-42 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 SUPERFAMILY SSF54713 57 92 3.43E-42 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 2.1E-75 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 SUPERFAMILY SSF46934 3 56 2.45E-15 T 09-03-2017 IPR009060 UBA-like GO:0005515 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Gene3D G3DSA:1.10.8.10 3 55 6.8E-24 T 09-03-2017 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Gene3D G3DSA:1.10.286.20 198 240 1.1E-17 T 09-03-2017 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Pfam PF00889 Elongation factor TS 71 277 3.0E-61 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.726 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Gene3D G3DSA:3.30.479.20 57 93 2.4E-26 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Gene3D G3DSA:3.30.479.20 243 277 2.4E-26 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS11805 0d6dc23a725fe75820676e2b84e6da42 278 Gene3D G3DSA:3.30.479.20 182 197 2.4E-26 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 SUPERFAMILY SSF50715 4 182 5.23E-49 T 09-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 93 2.0E-29 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 Gene3D G3DSA:2.40.240.10 5 93 4.0E-27 T 09-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 175 1.7E-46 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 178 25.579 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 Gene3D G3DSA:2.170.120.20 96 184 6.0E-23 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 Pfam PF01386 Ribosomal L25p family 6 90 4.0E-24 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 ARZXY2_RS12765 67ee24ab602c9bd4cda4340babda33d6 200 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 177 7.3E-21 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Pfam PF01336 OB-fold nucleic acid binding domain 1024 1100 4.5E-8 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 322 762 2.3E-162 T 09-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Gene3D G3DSA:2.40.50.140 1019 1098 3.0E-4 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 SUPERFAMILY SSF89550 123 293 1.14E-33 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 SUPERFAMILY SSF89550 8 94 1.14E-33 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Gene3D G3DSA:3.20.20.140 8 287 1.0E-41 T 09-03-2017 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 SMART SM00481 9 76 3.8E-25 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Pfam PF14579 Helix-hairpin-helix motif 835 924 8.9E-27 T 09-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 Pfam PF02811 PHP domain 10 197 7.6E-41 T 09-03-2017 IPR004013 PHP domain GO:0003824 ARZXY2_RS10790 4dce6953f799cf0e2e9967ff0d4fab40 1185 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 8 1062 0.0 T 09-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 Gene3D G3DSA:3.90.1030.10 4 116 4.5E-41 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 SUPERFAMILY SSF64263 1 117 6.67E-43 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 24.464 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 2.2E-35 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03675 f64c51f1f98c4b971124324bcc851add 186 Pfam PF01196 Ribosomal protein L17 20 116 1.4E-32 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 Gene3D G3DSA:1.10.10.10 9 81 9.0E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 SUPERFAMILY SSF55781 79 258 1.24E-40 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 SUPERFAMILY SSF46785 14 86 1.33E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 SMART SM00346 14 102 4.0E-29 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 Pfam PF09339 IclR helix-turn-helix domain 16 64 3.1E-17 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 Gene3D G3DSA:3.30.450.40 82 258 2.3E-48 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17075 e8089578dab3ed9f6edaf536c393f6c5 268 Pfam PF01614 Bacterial transcriptional regulator 131 256 4.2E-28 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Gene3D G3DSA:2.70.98.40 255 514 1.2E-60 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 262 512 1.4E-53 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Pfam PF00702 haloacid dehalogenase-like hydrolase 14 215 7.6E-13 T 09-03-2017 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Gene3D G3DSA:3.40.50.1000 106 248 6.5E-34 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Gene3D G3DSA:1.50.10.10 562 893 3.1E-95 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 SUPERFAMILY SSF56784 13 248 7.52E-36 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 SUPERFAMILY SSF48208 521 879 1.08E-66 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 110 222 4.0E-11 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 568 887 4.7E-101 T 09-03-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 ARZXY2_RS09965 9346f515f2a6b99cbdaa8ec599592ba0 899 SUPERFAMILY SSF74650 255 513 1.0E-50 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS10740 6e90200b663bc7a6e55d83a24a0df99f 178 Pfam PF00583 Acetyltransferase (GNAT) family 62 151 5.4E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS10740 6e90200b663bc7a6e55d83a24a0df99f 178 Gene3D G3DSA:3.40.630.30 41 159 1.1E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10740 6e90200b663bc7a6e55d83a24a0df99f 178 SUPERFAMILY SSF55729 40 168 1.49E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS15095 e3dd2631d80a5dd5fa60925716ba52c9 164 Pfam PF02082 Transcriptional regulator 1 82 1.4E-15 T 09-03-2017 IPR000944 Transcription regulator Rrf2-type ARZXY2_RS15095 e3dd2631d80a5dd5fa60925716ba52c9 164 Gene3D G3DSA:1.10.10.10 1 131 1.5E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15095 e3dd2631d80a5dd5fa60925716ba52c9 164 SUPERFAMILY SSF46785 2 132 2.73E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Gene3D G3DSA:3.40.50.1100 38 139 1.2E-38 T 09-03-2017 ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 SMART SM00116 415 460 88.0 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 SMART SM00116 345 398 7.0E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 SUPERFAMILY SSF54631 344 459 1.39E-14 T 09-03-2017 ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 SUPERFAMILY SSF53686 1 324 8.64E-95 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Pfam PF00571 CBS domain 413 460 0.0028 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Pfam PF00571 CBS domain 344 396 2.9E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Gene3D G3DSA:3.10.580.10 343 460 1.5E-16 T 09-03-2017 ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 303 1.4E-66 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 460 4.4E-183 T 09-03-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 ARZXY2_RS03085 4809d3aa96c906651a9e0dba65f7b13f 461 Gene3D G3DSA:3.40.50.1100 140 317 5.0E-67 T 09-03-2017 ARZXY2_RS05390 f1f1b530a402300cf12af25bc10a963c 220 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 13 208 9.4E-48 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 ARZXY2_RS05390 f1f1b530a402300cf12af25bc10a963c 220 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 11 213 44.893 T 09-03-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 ARZXY2_RS05390 f1f1b530a402300cf12af25bc10a963c 220 Gene3D G3DSA:3.90.950.10 13 213 7.9E-76 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like ARZXY2_RS05390 f1f1b530a402300cf12af25bc10a963c 220 Pfam PF01725 Ham1 family 13 208 1.4E-53 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 ARZXY2_RS05390 f1f1b530a402300cf12af25bc10a963c 220 SUPERFAMILY SSF52972 13 212 2.3E-62 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like ARZXY2_RS03340 7ee0ce39493feea3313ef4f1251a0c66 140 SMART SM00248 89 118 0.045 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS03340 7ee0ce39493feea3313ef4f1251a0c66 140 SMART SM00248 56 85 3.1E-5 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS03340 7ee0ce39493feea3313ef4f1251a0c66 140 Pfam PF12796 Ankyrin repeats (3 copies) 28 117 3.5E-12 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS03340 7ee0ce39493feea3313ef4f1251a0c66 140 Gene3D G3DSA:1.25.40.20 28 139 2.9E-24 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS03340 7ee0ce39493feea3313ef4f1251a0c66 140 SUPERFAMILY SSF48403 27 139 4.04E-24 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS18305 3c29bd69c457045d525d4833f2544aef 368 Pfam PF04607 Region found in RelA / SpoT proteins 57 201 5.7E-17 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 ARZXY2_RS18305 3c29bd69c457045d525d4833f2544aef 368 Gene3D G3DSA:1.10.287.860 187 238 9.9E-6 T 09-03-2017 ARZXY2_RS18305 3c29bd69c457045d525d4833f2544aef 368 SUPERFAMILY SSF81301 22 233 1.52E-27 T 09-03-2017 ARZXY2_RS18305 3c29bd69c457045d525d4833f2544aef 368 SMART SM00954 57 204 4.4E-15 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 ARZXY2_RS18305 3c29bd69c457045d525d4833f2544aef 368 Gene3D G3DSA:3.30.460.10 25 184 1.7E-19 T 09-03-2017 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 646 29.191 T 09-03-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SUPERFAMILY SSF46600 194 245 4.05E-12 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Pfam PF01541 GIY-YIG catalytic domain 18 92 4.1E-9 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Pfam PF02151 UvrB/uvrC motif 207 241 2.3E-10 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Gene3D G3DSA:3.40.1440.10 17 96 1.2E-8 T 09-03-2017 IPR027299 GIY-YIG domain ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SMART SM00278 627 646 0.99 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SMART SM00278 595 614 19.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Gene3D G3DSA:4.10.860.10 186 245 2.5E-17 T 09-03-2017 IPR001943 UVR domain GO:0005515 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 581 4.3E-51 T 09-03-2017 IPR001162 UvrC family homology region ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SUPERFAMILY SSF47781 554 653 6.04E-25 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 12 470 5.6E-124 T 09-03-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Pfam PF12826 Helix-hairpin-helix motif 599 653 1.4E-9 T 09-03-2017 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SUPERFAMILY SSF82771 17 101 1.2E-22 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 Gene3D G3DSA:1.10.150.20 595 647 1.1E-20 T 09-03-2017 ARZXY2_RS09100 411ba09aed944c90530533a3b75f63f5 670 SMART SM00465 17 99 1.1E-19 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 Gene3D G3DSA:3.90.180.10 1 162 1.3E-36 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 Pfam PF00107 Zinc-binding dehydrogenase 170 288 2.5E-12 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 Gene3D G3DSA:3.40.50.720 163 284 5.1E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 130 1.3E-15 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 SUPERFAMILY SSF50129 1 169 6.92E-42 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00800 42f16a3af99c56e5947526db86a1869e 355 SUPERFAMILY SSF51735 137 289 8.42E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10705 0abc47cea687b33520dc46814e6eba8f 539 Pfam PF00069 Protein kinase domain 17 228 1.1E-21 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 ARZXY2_RS10705 0abc47cea687b33520dc46814e6eba8f 539 SUPERFAMILY SSF56112 13 267 6.88E-40 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS10705 0abc47cea687b33520dc46814e6eba8f 539 Gene3D G3DSA:3.30.200.20 11 137 1.8E-17 T 09-03-2017 ARZXY2_RS10705 0abc47cea687b33520dc46814e6eba8f 539 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 51 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 ARZXY2_RS10705 0abc47cea687b33520dc46814e6eba8f 539 Gene3D G3DSA:1.10.510.10 138 266 1.5E-14 T 09-03-2017 ARZXY2_RS19200 04f12f56be268b2314ddd6afc84d57d9 384 Pfam PF13407 Periplasmic binding protein domain 75 342 1.3E-34 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS19200 04f12f56be268b2314ddd6afc84d57d9 384 Gene3D G3DSA:3.40.50.2300 206 370 4.5E-42 T 09-03-2017 ARZXY2_RS19200 04f12f56be268b2314ddd6afc84d57d9 384 Gene3D G3DSA:3.40.50.2300 72 205 9.5E-15 T 09-03-2017 ARZXY2_RS19200 04f12f56be268b2314ddd6afc84d57d9 384 SUPERFAMILY SSF53822 120 371 3.73E-52 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS04800 84656fe379db41ff4eaba3b37ace2091 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 53 1.3E-9 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS04800 84656fe379db41ff4eaba3b37ace2091 71 Pfam PF12728 Helix-turn-helix domain 4 55 2.3E-11 T 09-03-2017 ARZXY2_RS04620 d27b009ac2c7617ce3b28f018bfcd1e5 259 Pfam PF02585 GlcNAc-PI de-N-acetylase 23 152 1.3E-27 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS04620 d27b009ac2c7617ce3b28f018bfcd1e5 259 SUPERFAMILY SSF102588 21 248 2.62E-47 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS04620 d27b009ac2c7617ce3b28f018bfcd1e5 259 Gene3D G3DSA:3.40.50.10320 20 250 5.9E-54 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 09-03-2017 IPR019844 Cold-shock conserved site ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 SUPERFAMILY SSF50249 1 66 1.09E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 Gene3D G3DSA:2.40.50.140 1 66 1.9E-31 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 SMART SM00357 3 67 3.7E-29 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.2E-30 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 PRINTS PR00050 Cold shock protein signature 40 58 5.3E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 PRINTS PR00050 Cold shock protein signature 4 19 5.3E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 PRINTS PR00050 Cold shock protein signature 25 34 5.3E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS05285 1d206566e57162f354b030c7b2373f75 67 PIRSF PIRSF002599 1 67 8.6E-24 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 ARZXY2_RS01830 344d5dd012de23451ee13965b7251062 401 Gene3D G3DSA:3.40.50.300 174 356 3.0E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01830 344d5dd012de23451ee13965b7251062 401 SUPERFAMILY SSF52540 66 354 1.11E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01830 344d5dd012de23451ee13965b7251062 401 Pfam PF00437 Type II/IV secretion system protein 75 350 1.2E-67 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 ARZXY2_RS01830 344d5dd012de23451ee13965b7251062 401 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 24 360 4.5E-148 T 09-03-2017 IPR022399 Helicase/secretion neighbourhood ATPase ARZXY2_RS01830 344d5dd012de23451ee13965b7251062 401 Gene3D G3DSA:3.30.450.90 73 167 2.9E-27 T 09-03-2017 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 419 1.1E-160 T 09-03-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Gene3D G3DSA:1.20.970.10 8 73 2.1E-24 T 09-03-2017 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 122 137 - T 09-03-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 348 419 2.1E-20 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 SUPERFAMILY SSF47648 7 75 7.2E-18 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 SMART SM00941 346 420 7.6E-30 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Pfam PF00591 Glycosyl transferase family, a/b domain 89 301 2.2E-30 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 SUPERFAMILY SSF52418 87 328 3.92E-78 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 PIRSF PIRSF000478 6 436 1.3E-143 T 09-03-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 72 1.7E-15 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Gene3D G3DSA:3.90.1170.30 330 422 1.1E-28 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 Gene3D G3DSA:3.40.1030.10 87 328 3.7E-104 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS13150 d33383e2f5f5319b4611bb5a73dd8d25 436 SUPERFAMILY SSF54680 333 427 1.11E-23 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 SUPERFAMILY SSF55347 142 317 1.8E-34 T 09-03-2017 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 Gene3D G3DSA:3.30.360.10 157 300 6.6E-48 T 09-03-2017 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 Gene3D G3DSA:3.30.360.10 347 397 6.6E-48 T 09-03-2017 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 Gene3D G3DSA:3.40.50.720 3 156 2.5E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 220 9.9E-11 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 126 8.6E-27 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS11655 78a367186a6fa397c2cd411705ae6b90 400 SUPERFAMILY SSF51735 4 168 1.58E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 1.0E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 SUPERFAMILY SSF51905 5 334 3.5E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 Gene3D G3DSA:3.50.50.60 5 105 4.6E-25 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 Gene3D G3DSA:3.50.50.60 106 326 8.0E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.9E-9 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.9E-9 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.9E-9 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 3.7E-14 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.7E-14 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 3.7E-14 T 09-03-2017 ARZXY2_RS14710 1728ba5dc8f1b7d620a4b51d95bf4704 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.7E-14 T 09-03-2017 ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 Pfam PF08274 PhnA Zinc-Ribbon 4 33 3.7E-15 T 09-03-2017 IPR013987 PhnA protein, N-terminal ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 Gene3D G3DSA:2.30.30.40 47 117 6.9E-35 T 09-03-2017 ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 117 2.2E-40 T 09-03-2017 IPR004624 PhnA protein ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 SUPERFAMILY SSF82057 45 117 2.52E-26 T 09-03-2017 ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 Pfam PF03831 PhnA domain 48 117 1.4E-32 T 09-03-2017 IPR013988 PhnA protein, C-terminal ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 SUPERFAMILY SSF57783 4 36 4.76E-13 T 09-03-2017 ARZXY2_RS12610 d2f7726f9f50fda7d97ce211387e5b5c 117 Gene3D G3DSA:2.20.25.10 3 39 1.3E-19 T 09-03-2017 ARZXY2_RS01780 1bef2aa3c25591f1999dfc2547c0ff46 246 Pfam PF00005 ABC transporter 20 172 4.4E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01780 1bef2aa3c25591f1999dfc2547c0ff46 246 SMART SM00382 29 229 1.4E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01780 1bef2aa3c25591f1999dfc2547c0ff46 246 Gene3D G3DSA:3.40.50.300 2 225 7.8E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01780 1bef2aa3c25591f1999dfc2547c0ff46 246 SUPERFAMILY SSF52540 4 224 1.36E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 135 152 - T 09-03-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 SUPERFAMILY SSF53850 42 335 8.84E-76 T 09-03-2017 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 Gene3D G3DSA:3.40.190.10 141 279 7.0E-53 T 09-03-2017 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 Pfam PF13343 Bacterial extracellular solute-binding protein 90 317 9.4E-29 T 09-03-2017 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 Gene3D G3DSA:3.40.190.10 280 333 6.1E-36 T 09-03-2017 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 Gene3D G3DSA:3.40.190.10 10 136 6.1E-36 T 09-03-2017 ARZXY2_RS15435 ba296f668aedaa8882ccb2365fde04da 347 PIRSF PIRSF002825 1 347 6.6E-86 T 09-03-2017 IPR026045 Ferric binding protein ARZXY2_RS13350 5c91562bb11db7a7bee7e3baf7d4a2f5 365 Pfam PF13407 Periplasmic binding protein domain 47 319 1.7E-61 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS13350 5c91562bb11db7a7bee7e3baf7d4a2f5 365 SUPERFAMILY SSF53822 44 352 3.3E-59 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS13350 5c91562bb11db7a7bee7e3baf7d4a2f5 365 Gene3D G3DSA:3.40.50.2300 45 158 1.4E-22 T 09-03-2017 ARZXY2_RS13350 5c91562bb11db7a7bee7e3baf7d4a2f5 365 Gene3D G3DSA:3.40.50.2300 159 352 1.2E-35 T 09-03-2017 ARZXY2_RS13955 6f31144326c902cdb76325ebd08b93fc 138 Pfam PF13279 Thioesterase-like superfamily 2 125 7.2E-9 T 09-03-2017 ARZXY2_RS13955 6f31144326c902cdb76325ebd08b93fc 138 Gene3D G3DSA:3.10.129.10 2 136 2.4E-31 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS13955 6f31144326c902cdb76325ebd08b93fc 138 SUPERFAMILY SSF54637 2 136 1.14E-20 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02270 e004ee87100e328d8a24e7da5f5f9ad3 218 Pfam PF13599 Pentapeptide repeats (9 copies) 51 137 3.0E-8 T 09-03-2017 IPR001646 Pentapeptide repeat ARZXY2_RS02270 e004ee87100e328d8a24e7da5f5f9ad3 218 SUPERFAMILY SSF141571 29 187 6.97E-27 T 09-03-2017 ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 SUPERFAMILY SSF56042 183 356 5.08E-53 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 SUPERFAMILY SSF55326 16 180 2.24E-43 T 09-03-2017 ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 Gene3D G3DSA:3.30.1330.10 32 180 1.0E-49 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 16 380 40.829 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 Pfam PF02769 AIR synthase related protein, C-terminal domain 187 355 2.1E-28 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 175 1.4E-15 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 16 353 1.2E-121 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01125 6479215052756a3901755d73fb94c737 384 Gene3D G3DSA:3.90.650.10 183 356 1.3E-63 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 SUPERFAMILY SSF46946 2 122 1.44E-46 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 09-03-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 Gene3D G3DSA:1.10.8.50 1 72 3.7E-31 T 09-03-2017 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 PIRSF PIRSF002134 1 125 2.1E-44 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 Gene3D G3DSA:4.10.910.10 73 123 7.3E-26 T 09-03-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.05 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 8.8E-52 T 09-03-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03660 064d4e408d15c75cac0e3fac746c5c54 125 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.7E-32 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 20 99 2.5E-13 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 100 14.548 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 85 98 2.1E-6 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 64 80 2.1E-6 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 30 46 2.1E-6 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS14545 63a65d88265fce9dde8fea006e5dffaa 100 Pfam PF02049 Flagellar hook-basal body complex protein FliE 20 99 4.4E-21 T 09-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 ARZXY2_RS22330 01a49979edb0af69e186f98047250b46 106 SUPERFAMILY SSF51735 3 105 3.45E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS22330 01a49979edb0af69e186f98047250b46 106 Gene3D G3DSA:3.40.50.720 3 105 4.4E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS22330 01a49979edb0af69e186f98047250b46 106 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 75 6.6E-11 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS12565 d190326b5de926392bea326dfc1be7ec 533 Pfam PF02435 Levansucrase/Invertase 72 512 2.5E-135 T 09-03-2017 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 ARZXY2_RS12565 d190326b5de926392bea326dfc1be7ec 533 SUPERFAMILY SSF75005 66 503 1.68E-61 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS12565 d190326b5de926392bea326dfc1be7ec 533 Gene3D G3DSA:2.115.10.20 61 513 2.9E-143 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 269 355 1.1E-10 T 09-03-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 Gene3D G3DSA:3.30.230.10 224 358 9.3E-23 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 SUPERFAMILY SSF50156 166 222 2.04E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 SUPERFAMILY SSF54211 207 359 2.84E-22 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 Pfam PF13180 PDZ domain 169 235 6.0E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04570 1c5f4689c1455178f40ab3d4151d939a 379 Gene3D G3DSA:2.30.42.10 162 223 3.9E-12 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 Gene3D G3DSA:3.40.1160.10 33 306 2.2E-104 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 Pfam PF00696 Amino acid kinase family 35 284 4.1E-46 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 TIGRFAM TIGR00761 argB: acetylglutamate kinase 35 282 6.9E-74 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 SUPERFAMILY SSF53633 11 309 6.41E-87 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 PIRSF PIRSF000728 16 306 6.4E-101 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 PRINTS PR00474 Glutamate 5-kinase family signature 206 233 3.8E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 PRINTS PR00474 Glutamate 5-kinase family signature 65 79 3.8E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 PRINTS PR00474 Glutamate 5-kinase family signature 257 277 3.8E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS11220 e5fb6e47c3868ec5ad141fce9fa769c2 313 Hamap MF_00082_B Acetylglutamate kinase [argB]. 32 307 34.478 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS03715 ff049fbbe4f8d4bb688ba65297d7645e 135 Pfam PF07811 TadE-like protein 9 51 2.6E-16 T 09-03-2017 IPR012495 TadE-like ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 SUPERFAMILY SSF52540 23 231 7.41E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 Gene3D G3DSA:3.30.300.20 207 315 1.7E-34 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 153 2.2E-19 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 SUPERFAMILY SSF54814 201 320 1.11E-33 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 TIGRFAM TIGR00436 era: GTP-binding protein Era 22 303 7.6E-62 T 09-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 Pfam PF07650 KH domain 227 309 1.2E-15 T 09-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 Gene3D G3DSA:3.40.50.300 23 192 2.0E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 Hamap MF_00367 GTPase Era [era]. 17 320 33.51 T 09-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 ARZXY2_RS08315 5358f23a4f31916e8bdc9d7c6af8c011 320 Pfam PF01926 50S ribosome-binding GTPase 23 137 5.4E-21 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS08070 dad9f22fb13d4a0baf248edb8433adeb 577 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 238 568 6.3E-36 T 09-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like ARZXY2_RS08070 dad9f22fb13d4a0baf248edb8433adeb 577 Gene3D G3DSA:3.30.160.60 535 567 5.0E-5 T 09-03-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 ARZXY2_RS08070 dad9f22fb13d4a0baf248edb8433adeb 577 Pfam PF02618 YceG-like family 277 563 2.0E-58 T 09-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 Pfam PF00199 Catalase 64 449 4.9E-166 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 139 157 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 77 100 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 160 177 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 179 197 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 349 376 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PRINTS PR00067 Catalase signature 381 407 6.5E-68 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 Gene3D G3DSA:2.40.180.10 54 419 1.2E-170 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 SUPERFAMILY SSF56634 56 567 3.14E-206 T 09-03-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 SUPERFAMILY SSF52317 575 706 7.08E-14 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 394 402 - T 09-03-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 PIRSF PIRSF038927 36 739 8.9E-294 T 09-03-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 Gene3D G3DSA:3.40.50.880 575 735 1.0E-41 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 SMART SM01060 64 452 5.1E-252 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 Pfam PF06628 Catalase-related immune-responsive 481 544 2.2E-22 T 09-03-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS09400 6f059fea078384cba2c17a3b1f41a98c 740 ProSitePatterns PS00438 Catalase proximal active site signature. 100 116 - T 09-03-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 SMART SM00278 267 286 140.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 SMART SM00278 237 256 0.16 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 Pfam PF10531 SLBB domain 134 188 1.8E-14 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 Pfam PF12836 Helix-hairpin-helix motif 226 288 1.9E-22 T 09-03-2017 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 SUPERFAMILY SSF47781 221 289 1.89E-27 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 Gene3D G3DSA:1.10.150.320 222 289 2.1E-20 T 09-03-2017 ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 225 288 9.0E-16 T 09-03-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain ARZXY2_RS08230 93907fd30e7ac3dcfd34dc876ba8f401 292 Gene3D G3DSA:3.10.560.10 132 177 2.6E-7 T 09-03-2017 ARZXY2_RS16110 9861a15a358931b1ca4809c6a4070f7e 420 Gene3D G3DSA:1.20.1250.20 23 196 2.5E-22 T 09-03-2017 ARZXY2_RS16110 9861a15a358931b1ca4809c6a4070f7e 420 SUPERFAMILY SSF103473 11 405 6.15E-51 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16110 9861a15a358931b1ca4809c6a4070f7e 420 Gene3D G3DSA:1.20.1250.20 223 402 3.0E-21 T 09-03-2017 ARZXY2_RS16110 9861a15a358931b1ca4809c6a4070f7e 420 Pfam PF05977 Transmembrane secretion effector 4 400 2.4E-56 T 09-03-2017 IPR010290 Transmembrane secretion effector ARZXY2_RS02565 74cf58d5b8ab7e0cd3961c15612df9fc 685 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 341 668 1.5E-24 T 09-03-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 SMART SM00387 267 384 3.1E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 1.2E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 1.2E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 381 1.2E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 SUPERFAMILY SSF47384 144 223 1.94E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 SMART SM00388 158 222 3.3E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 Gene3D G3DSA:3.30.565.10 209 383 4.1E-35 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 Gene3D G3DSA:1.10.287.130 151 208 3.5E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 SUPERFAMILY SSF55874 211 382 2.1E-35 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 382 9.6E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11475 72c1f18d4762cd6194b74fb5f741bb5f 396 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 222 9.9E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS15255 92092f264bf0352cc31bbd97cb063afb 337 SUPERFAMILY SSF50129 11 165 5.09E-16 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS15255 92092f264bf0352cc31bbd97cb063afb 337 SUPERFAMILY SSF51735 132 276 1.24E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15255 92092f264bf0352cc31bbd97cb063afb 337 Gene3D G3DSA:3.90.180.10 123 156 1.8E-6 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS15255 92092f264bf0352cc31bbd97cb063afb 337 Gene3D G3DSA:3.40.50.720 157 267 3.5E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15255 92092f264bf0352cc31bbd97cb063afb 337 Gene3D G3DSA:3.90.180.10 21 122 5.1E-4 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 26 439 2.4E-107 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 PIRSF PIRSF000505 18 451 1.8E-111 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 ProSitePatterns PS00104 EPSP synthase signature 1. 110 124 - T 09-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 ProSitePatterns PS00885 EPSP synthase signature 2. 360 378 - T 09-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 Gene3D G3DSA:3.65.10.10 234 444 4.3E-53 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 Gene3D G3DSA:3.65.10.10 37 233 9.2E-55 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 32 445 1.3E-113 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 SUPERFAMILY SSF55205 27 443 2.62E-98 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ARZXY2_RS05020 a8f755354dbc09e449963a9a06b7cd07 465 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 27 447 28.151 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 ARZXY2_RS20245 2727a25642172c9621f2cad154a5430e 109 SUPERFAMILY SSF46785 5 104 1.36E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20245 2727a25642172c9621f2cad154a5430e 109 Pfam PF03551 Transcriptional regulator PadR-like family 17 89 9.8E-21 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS20245 2727a25642172c9621f2cad154a5430e 109 Gene3D G3DSA:1.10.10.10 3 106 6.4E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04735 afa8e037cc280c0ecbd1f6a1e45acab9 366 Pfam PF14258 Domain of unknown function (DUF4350) 34 94 2.0E-7 T 09-03-2017 IPR025646 Domain of unknown function DUF4350 ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 Gene3D G3DSA:3.40.50.720 178 291 9.6E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 SUPERFAMILY SSF51735 148 311 1.76E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 SUPERFAMILY SSF50129 7 172 5.78E-55 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 9.9E-30 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 Gene3D G3DSA:3.90.180.10 3 177 2.0E-66 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 Pfam PF00107 Zinc-binding dehydrogenase 185 307 8.2E-19 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS09295 a2670b7dce51b319db13451ca4c6dd9f 347 SMART SM00829 11 341 7.3E-8 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS20320 76ca18caa5b50965c20666c1facaaa43 317 Pfam PF01522 Polysaccharide deacetylase 55 160 2.6E-18 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS20320 76ca18caa5b50965c20666c1facaaa43 317 Gene3D G3DSA:3.20.20.370 11 283 2.5E-75 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS20320 76ca18caa5b50965c20666c1facaaa43 317 SUPERFAMILY SSF88713 9 281 1.38E-64 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 2.9E-35 T 09-03-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 PIRSF PIRSF000460 2 821 3.9E-246 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 Gene3D G3DSA:3.40.50.2000 27 433 1.1E-82 T 09-03-2017 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 SUPERFAMILY SSF53756 7 768 1.77E-189 T 09-03-2017 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 Gene3D G3DSA:3.40.50.2000 434 738 1.3E-87 T 09-03-2017 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 734 2.8E-223 T 09-03-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 Pfam PF00343 Carbohydrate phosphorylase 128 173 1.4E-5 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS14845 48ecb9033a246ffe21e106ad0c8b948a 877 Pfam PF00343 Carbohydrate phosphorylase 280 633 1.4E-16 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 Gene3D G3DSA:3.30.499.10 3 157 6.5E-24 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 Gene3D G3DSA:3.30.499.10 340 471 3.5E-58 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 SUPERFAMILY SSF53732 2 471 7.32E-161 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 Gene3D G3DSA:3.40.1060.10 158 293 9.6E-40 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 ProSitePatterns PS01244 Aconitase family signature 2. 404 417 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 2 464 3.5E-222 T 09-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 Pfam PF00330 Aconitase family (aconitate hydratase) 7 462 3.0E-152 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 471 59.359 T 09-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 138 153 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 200 213 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 348 359 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 87 100 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 113 121 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 214 227 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 291 305 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 124 137 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 PRINTS PR00415 Aconitase family signature 404 417 1.2E-45 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS05750 5903acbdbd0c3f0e90a8d5a1521e4cae 483 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 ARZXY2_RS00275 3a6b3e4af8b61510de3ed645095d2c37 389 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 140 3.6E-12 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS00275 3a6b3e4af8b61510de3ed645095d2c37 389 SUPERFAMILY SSF55347 148 350 2.83E-27 T 09-03-2017 ARZXY2_RS00275 3a6b3e4af8b61510de3ed645095d2c37 389 Gene3D G3DSA:3.40.50.720 6 151 3.2E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00275 3a6b3e4af8b61510de3ed645095d2c37 389 Gene3D G3DSA:3.30.360.10 152 380 8.3E-36 T 09-03-2017 ARZXY2_RS00275 3a6b3e4af8b61510de3ed645095d2c37 389 SUPERFAMILY SSF51735 5 175 6.68E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11660 5403d7389b716be0a722ad2d0573074f 334 Pfam PF01261 Xylose isomerase-like TIM barrel 23 273 1.8E-38 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS11660 5403d7389b716be0a722ad2d0573074f 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 330 5.9E-22 T 09-03-2017 IPR011418 AP endonuclease, family 2, C-terminal ARZXY2_RS11660 5403d7389b716be0a722ad2d0573074f 334 SUPERFAMILY SSF51658 11 318 9.03E-56 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS11660 5403d7389b716be0a722ad2d0573074f 334 Gene3D G3DSA:3.20.20.150 2 317 4.0E-72 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16145 4727f8274666736be707b37d68cff314 140 PIRSF PIRSF017349 4 139 2.0E-50 T 09-03-2017 IPR014487 Protein of unknown function DUF3151 ARZXY2_RS16145 4727f8274666736be707b37d68cff314 140 Pfam PF11349 Protein of unknown function (DUF3151) 11 135 1.5E-55 T 09-03-2017 IPR014487 Protein of unknown function DUF3151 ARZXY2_RS10040 43d55fac05daad26c1930da3f585a5e5 93 SUPERFAMILY SSF52402 12 86 4.77E-19 T 09-03-2017 ARZXY2_RS10040 43d55fac05daad26c1930da3f585a5e5 93 PRINTS PR01438 Universal stress protein signature 44 56 2.5E-8 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS10040 43d55fac05daad26c1930da3f585a5e5 93 PRINTS PR01438 Universal stress protein signature 62 84 2.5E-8 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS10040 43d55fac05daad26c1930da3f585a5e5 93 Gene3D G3DSA:3.40.50.620 9 84 4.2E-19 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS10040 43d55fac05daad26c1930da3f585a5e5 93 Pfam PF00582 Universal stress protein family 32 84 4.2E-13 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS19270 1844ebd16c6661c85604ce127f578f1b 248 Pfam PF13673 Acetyltransferase (GNAT) domain 61 146 9.5E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS19270 1844ebd16c6661c85604ce127f578f1b 248 SUPERFAMILY SSF55729 11 159 1.72E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS19270 1844ebd16c6661c85604ce127f578f1b 248 Gene3D G3DSA:3.40.630.30 12 159 1.3E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Gene3D G3DSA:3.30.70.80 41 128 6.1E-7 T 09-03-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 603 613 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Pfam PF00082 Subtilase family 170 658 5.3E-43 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 PRINTS PR00723 Subtilisin serine protease family (S8) signature 170 189 1.6E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 PRINTS PR00723 Subtilisin serine protease family (S8) signature 276 289 1.6E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 PRINTS PR00723 Subtilisin serine protease family (S8) signature 602 618 1.6E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 SUPERFAMILY SSF52743 556 670 6.55E-62 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 SUPERFAMILY SSF52743 159 190 6.55E-62 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 SUPERFAMILY SSF52743 243 449 6.55E-62 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Gene3D G3DSA:3.40.50.200 246 410 2.8E-66 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Gene3D G3DSA:3.40.50.200 129 191 2.8E-66 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Gene3D G3DSA:3.40.50.200 553 670 2.8E-66 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Pfam PF05922 Peptidase inhibitor I9 45 138 1.4E-8 T 09-03-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 ARZXY2_RS15880 347e370f3ecaf523fcfa92aa7c564f71 1033 Pfam PF02225 PA domain 454 519 8.0E-7 T 09-03-2017 IPR003137 PA domain ARZXY2_RS06140 137210efd433022027c51819857fa002 760 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 161 756 3.2E-161 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF81653 257 352 4.05E-23 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Gene3D G3DSA:3.30.70.100 11 78 2.7E-21 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 454 460 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Pfam PF00403 Heavy-metal-associated domain 17 75 7.7E-12 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Gene3D G3DSA:3.40.1110.10 467 578 7.3E-23 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF55008 10 79 4.19E-17 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 225 736 2.5E-82 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 ProSitePatterns PS01047 Heavy-metal-associated domain. 19 47 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 375 389 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 222 241 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 435 450 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 29 43 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 242 260 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00943 Copper-transporting ATPase signature 630 647 7.3E-12 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 179 755 1.6E-180 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Pfam PF00122 E1-E2 ATPase 223 443 5.6E-65 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Gene3D G3DSA:3.40.50.1000 425 466 5.6E-49 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Gene3D G3DSA:3.40.50.1000 579 721 5.6E-49 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Pfam PF00702 haloacid dehalogenase-like hydrolase 448 667 6.4E-39 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF56784 508 753 6.98E-55 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF56784 450 470 6.98E-55 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 466 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 608 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 587 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 7.5E-24 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 Gene3D G3DSA:2.70.150.10 179 353 1.4E-26 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF81665 702 720 8.63E-15 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF81665 353 446 8.63E-15 T 09-03-2017 ARZXY2_RS06140 137210efd433022027c51819857fa002 760 SUPERFAMILY SSF81665 218 256 8.63E-15 T 09-03-2017 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Gene3D G3DSA:3.30.70.870 424 493 3.2E-21 T 09-03-2017 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF50447 308 418 1.31E-25 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF50447 259 278 1.31E-25 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF54980 618 698 2.45E-18 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 PRINTS PR00315 GTP-binding elongation factor signature 39 52 2.1E-7 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 PRINTS PR00315 GTP-binding elongation factor signature 87 95 2.1E-7 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 PRINTS PR00315 GTP-binding elongation factor signature 121 132 2.1E-7 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 PRINTS PR00315 GTP-binding elongation factor signature 105 115 2.1E-7 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 38 172 4.1E-16 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF54211 501 612 1.29E-32 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF54980 421 487 2.84E-14 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Gene3D G3DSA:3.30.70.240 618 699 4.1E-22 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Gene3D G3DSA:2.40.30.10 312 423 1.4E-24 T 09-03-2017 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Pfam PF00009 Elongation factor Tu GTP binding domain 36 290 3.4E-35 T 09-03-2017 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SMART SM00889 497 615 4.7E-50 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Pfam PF03144 Elongation factor Tu domain 2 332 408 1.1E-9 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Gene3D G3DSA:3.40.50.300 32 294 4.6E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Pfam PF03764 Elongation factor G, domain IV 500 613 4.3E-35 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Gene3D G3DSA:3.30.230.10 501 617 3.9E-45 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Pfam PF00679 Elongation factor G C-terminus 617 698 5.3E-20 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 Pfam PF14492 Elongation Factor G, domain II 422 492 2.1E-21 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SMART SM00838 617 699 8.8E-16 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS09280 4bd90338d1ad8c93a29a39dcd304121b 699 SUPERFAMILY SSF52540 34 290 2.85E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01085 59dd2b61f09b516d06488af6e8184a90 205 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 34 123 5.5E-14 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 ARZXY2_RS01085 59dd2b61f09b516d06488af6e8184a90 205 SUPERFAMILY SSF50475 33 148 4.75E-17 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS01085 59dd2b61f09b516d06488af6e8184a90 205 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 8 203 5.7E-72 T 09-03-2017 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent ARZXY2_RS01085 59dd2b61f09b516d06488af6e8184a90 205 Gene3D G3DSA:2.30.110.10 21 148 2.4E-29 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS15535 67fb4f938a443836e107fb394a44dc7f 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 209 7.2E-13 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS15535 67fb4f938a443836e107fb394a44dc7f 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 291 1.9E-67 T 09-03-2017 IPR010099 Epimerase family protein SDR39U1 ARZXY2_RS15535 67fb4f938a443836e107fb394a44dc7f 299 Gene3D G3DSA:3.40.50.720 5 240 3.2E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15535 67fb4f938a443836e107fb394a44dc7f 299 SUPERFAMILY SSF51735 1 287 2.38E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15535 67fb4f938a443836e107fb394a44dc7f 299 Pfam PF08338 Domain of unknown function (DUF1731) 245 294 3.2E-13 T 09-03-2017 IPR013549 Domain of unknown function DUF1731 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 Gene3D G3DSA:1.10.3730.10 166 270 9.2E-32 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 SUPERFAMILY SSF51735 4 165 5.46E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 167 270 1.6E-29 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 SUPERFAMILY SSF48179 166 274 9.01E-31 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 227 249 - T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 PIRSF PIRSF000193 2 274 1.6E-73 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 103 2.5E-17 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 271 6.0E-69 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 Gene3D G3DSA:3.40.50.720 2 165 6.5E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01915 782e8e99d7d10b9b32a783f5b778c2f1 276 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 271 24.058 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 ARZXY2_RS07355 694658ba4d64e9ffe029d4eee1dd20b0 164 PIRSF PIRSF000239 9 164 6.1E-27 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS07355 694658ba4d64e9ffe029d4eee1dd20b0 164 Gene3D G3DSA:3.40.30.10 7 161 1.2E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07355 694658ba4d64e9ffe029d4eee1dd20b0 164 Pfam PF00578 AhpC/TSA family 16 139 1.3E-39 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS07355 694658ba4d64e9ffe029d4eee1dd20b0 164 SUPERFAMILY SSF52833 12 161 1.76E-49 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 10 373 42.932 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 24 364 7.6E-127 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 Gene3D G3DSA:3.40.50.1820 35 364 7.1E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 SUPERFAMILY SSF53474 18 367 1.45E-89 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 PIRSF PIRSF000443 2 377 2.1E-123 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 ARZXY2_RS12240 c7c6c4c24cd824de8b99a6887788bf86 379 Pfam PF00561 alpha/beta hydrolase fold 53 359 7.6E-30 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS04175 dcd9d65b6b40856b69c39b12b9b9ada2 414 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 342 353 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site ARZXY2_RS04175 dcd9d65b6b40856b69c39b12b9b9ada2 414 SUPERFAMILY SSF50494 203 367 5.47E-7 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS07525 42f1bc990d3a3f858d53b304b8d4916e 301 Gene3D G3DSA:3.10.129.10 33 133 2.7E-42 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS07525 42f1bc990d3a3f858d53b304b8d4916e 301 SUPERFAMILY SSF54637 134 299 1.39E-50 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS07525 42f1bc990d3a3f858d53b304b8d4916e 301 SUPERFAMILY SSF54637 31 132 1.56E-36 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS07525 42f1bc990d3a3f858d53b304b8d4916e 301 Gene3D G3DSA:3.10.129.10 144 300 8.7E-56 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS07525 42f1bc990d3a3f858d53b304b8d4916e 301 Pfam PF13622 Thioesterase-like superfamily 44 298 6.9E-57 T 09-03-2017 ARZXY2_RS02745 e9f260548f0978e22be00142f3d54d4a 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 312 1.1E-12 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02745 e9f260548f0978e22be00142f3d54d4a 316 SUPERFAMILY SSF161098 75 303 1.44E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02745 e9f260548f0978e22be00142f3d54d4a 316 Gene3D G3DSA:1.20.58.370 29 61 2.0E-6 T 09-03-2017 ARZXY2_RS02745 e9f260548f0978e22be00142f3d54d4a 316 SUPERFAMILY SSF160964 30 61 1.44E-6 T 09-03-2017 ARZXY2_RS02745 e9f260548f0978e22be00142f3d54d4a 316 Gene3D G3DSA:1.10.3720.10 81 312 5.0E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 SUPERFAMILY SSF54506 28 320 8.98E-35 T 09-03-2017 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 Gene3D G3DSA:3.10.310.10 159 298 7.7E-31 T 09-03-2017 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 Pfam PF01678 Diaminopimelate epimerase 190 301 1.1E-16 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 Pfam PF01678 Diaminopimelate epimerase 29 162 1.6E-28 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 27 322 26.415 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 Gene3D G3DSA:3.10.310.10 28 158 8.7E-37 T 09-03-2017 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 101 115 - T 09-03-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ARZXY2_RS11365 0ef7f75caaefd110c2dde66de5f9cd39 322 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 28 321 4.7E-56 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 Gene3D G3DSA:3.90.180.10 6 172 2.8E-48 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 SMART SM00829 17 339 0.0014 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 Gene3D G3DSA:3.40.50.720 173 286 5.7E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 SUPERFAMILY SSF51735 146 302 2.09E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 Pfam PF00107 Zinc-binding dehydrogenase 179 301 9.3E-17 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 SUPERFAMILY SSF50129 11 178 1.52E-43 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00875 1620b07664857f57d00b52e4390f68d2 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 137 1.4E-29 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS07305 aaf601fdb28e015d0c3937166e4fd4ca 409 SUPERFAMILY SSF102405 117 327 4.12E-32 T 09-03-2017 ARZXY2_RS07305 aaf601fdb28e015d0c3937166e4fd4ca 409 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 105 319 3.0E-59 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 ARZXY2_RS07305 aaf601fdb28e015d0c3937166e4fd4ca 409 Pfam PF02481 DNA recombination-mediator protein A 108 320 3.7E-66 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 ARZXY2_RS07305 aaf601fdb28e015d0c3937166e4fd4ca 409 Gene3D G3DSA:3.40.50.450 150 297 2.4E-11 T 09-03-2017 ARZXY2_RS11460 5b2457b4f865cf2395429f2203240d0b 164 Pfam PF01967 MoaC family 25 158 5.9E-53 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS11460 5b2457b4f865cf2395429f2203240d0b 164 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 14 160 1.3E-60 T 09-03-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS11460 5b2457b4f865cf2395429f2203240d0b 164 Gene3D G3DSA:3.30.70.640 13 163 7.7E-64 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS11460 5b2457b4f865cf2395429f2203240d0b 164 SUPERFAMILY SSF55040 21 163 4.58E-57 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 ARZXY2_RS11460 5b2457b4f865cf2395429f2203240d0b 164 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 12 164 33.867 T 09-03-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 Gene3D G3DSA:3.40.50.970 68 485 2.7E-154 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 Gene3D G3DSA:3.40.50.920 730 904 3.2E-64 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 SUPERFAMILY SSF52518 490 721 1.65E-84 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 PIRSF PIRSF000156 9 911 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 SUPERFAMILY SSF52922 725 902 8.9E-48 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 904 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 Gene3D G3DSA:3.40.50.970 490 725 1.9E-107 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 SUPERFAMILY SSF52518 69 486 1.52E-131 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07345 cd346b02855989d803753fc64f0f4316 917 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 318 5.0E-10 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 ProSitePatterns PS01117 MarR-type HTH domain signature. 78 112 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 Pfam PF12802 MarR family 55 103 1.7E-7 T 09-03-2017 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 SUPERFAMILY SSF46785 18 149 1.65E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 SMART SM00347 39 139 3.3E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 Gene3D G3DSA:1.10.10.10 20 149 2.4E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 2.8E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 2.8E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 2.8E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14690 b87d8931dd25e0c357d639cfe5bea8e2 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 2.8E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS03560 b8edc3ca2fc2369a09d3e32c58898d04 132 Gene3D G3DSA:3.30.1370.30 2 72 6.2E-27 T 09-03-2017 ARZXY2_RS03560 b8edc3ca2fc2369a09d3e32c58898d04 132 Gene3D G3DSA:3.30.1490.10 76 132 1.5E-27 T 09-03-2017 ARZXY2_RS03560 b8edc3ca2fc2369a09d3e32c58898d04 132 SUPERFAMILY SSF56047 3 132 4.19E-43 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03560 b8edc3ca2fc2369a09d3e32c58898d04 132 Pfam PF00410 Ribosomal protein S8 5 132 1.6E-48 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03560 b8edc3ca2fc2369a09d3e32c58898d04 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.378 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Pfam PF05199 GMC oxidoreductase 413 535 3.7E-25 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Pfam PF00732 GMC oxidoreductase 55 298 7.5E-13 T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 SUPERFAMILY SSF54373 412 485 2.82E-11 T 09-03-2017 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Gene3D G3DSA:3.50.50.60 217 323 3.1E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Gene3D G3DSA:3.50.50.60 9 146 3.1E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Gene3D G3DSA:3.50.50.60 423 436 3.1E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 Gene3D G3DSA:3.50.50.60 475 542 3.1E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 SUPERFAMILY SSF51905 9 321 6.22E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19240 a568e08d64b2b2fc2bba12bbe4898566 556 SUPERFAMILY SSF51905 481 544 6.22E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 SMART SM00421 855 912 1.5E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 Gene3D G3DSA:3.40.50.300 34 210 4.1E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 SUPERFAMILY SSF52540 52 236 1.04E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 SUPERFAMILY SSF46894 847 908 8.16E-16 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 Gene3D G3DSA:1.25.40.10 521 687 6.3E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 Pfam PF00196 Bacterial regulatory proteins, luxR family 857 908 2.5E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 Gene3D G3DSA:1.10.10.10 849 908 2.3E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 872 888 9.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 858 872 9.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12755 4e2675d366c6871351c7def7521f9cd6 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 900 9.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Gene3D G3DSA:1.10.8.60 780 861 9.1E-31 T 09-03-2017 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Gene3D G3DSA:3.40.50.300 159 343 3.6E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SUPERFAMILY SSF52540 551 850 7.98E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 854 0.0 T 09-03-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SUPERFAMILY SSF81923 4 156 6.38E-36 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SMART SM01086 769 860 4.7E-36 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 636 654 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 849 1.9E-26 T 09-03-2017 IPR019489 Clp ATPase, C-terminal ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Gene3D G3DSA:3.40.50.300 558 779 1.0E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Gene3D G3DSA:1.10.8.60 344 427 2.5E-35 T 09-03-2017 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SUPERFAMILY SSF52540 157 550 3.45E-91 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SMART SM00382 198 343 3.2E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 SMART SM00382 602 751 2.1E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Gene3D G3DSA:1.10.1780.10 4 148 1.4E-37 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 1.6E-13 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Pfam PF07724 AAA domain (Cdc48 subfamily) 601 763 7.2E-53 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 606 624 3.1E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 680 698 3.1E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 713 727 3.1E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 651 669 3.1E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 20 60 8.6E-9 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS01090 c17697ebc338537e3310c66143170913 890 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 5.5E-9 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 ARZXY2_RS15345 a5327a76ab89954051d1d5b21d2d3a95 219 SUPERFAMILY SSF46785 1 98 4.74E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15345 a5327a76ab89954051d1d5b21d2d3a95 219 Gene3D G3DSA:1.10.10.10 6 69 5.9E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15345 a5327a76ab89954051d1d5b21d2d3a95 219 SMART SM00418 15 100 0.009 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS15345 a5327a76ab89954051d1d5b21d2d3a95 219 Pfam PF12840 Helix-turn-helix domain 12 68 1.9E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15345 a5327a76ab89954051d1d5b21d2d3a95 219 Gene3D G3DSA:3.20.20.110 132 204 9.0E-4 T 09-03-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 SUPERFAMILY SSF50993 10 434 2.35E-38 T 09-03-2017 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 29 255 3.4E-20 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 Gene3D G3DSA:2.130.10.120 335 419 3.1E-4 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 Pfam PF00326 Prolyl oligopeptidase family 526 726 3.6E-44 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 583 603 1.2E-24 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 657 679 1.2E-24 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 638 653 1.2E-24 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 488 506 1.2E-24 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 SUPERFAMILY SSF53474 456 717 3.57E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS15065 064601acb7e21a78af654420c0af9624 729 Gene3D G3DSA:3.40.50.1820 420 725 2.1E-84 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02805 405e27065bf192e124f16df5b0797a1f 449 Pfam PF00425 chorismate binding enzyme 179 437 1.4E-65 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal ARZXY2_RS02805 405e27065bf192e124f16df5b0797a1f 449 Gene3D G3DSA:3.60.120.10 64 446 1.1E-83 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS02805 405e27065bf192e124f16df5b0797a1f 449 SUPERFAMILY SSF56322 31 446 2.49E-77 T 09-03-2017 IPR005801 ADC synthase GO:0009058 ARZXY2_RS02805 405e27065bf192e124f16df5b0797a1f 449 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 164 445 6.1E-73 T 09-03-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 ARZXY2_RS08775 b712193fcba1cca0daec348f805e4fd8 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 247 5.2E-49 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS08775 b712193fcba1cca0daec348f805e4fd8 339 SUPERFAMILY SSF51735 7 318 3.14E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08775 b712193fcba1cca0daec348f805e4fd8 339 Gene3D G3DSA:3.90.25.10 183 305 4.5E-25 T 09-03-2017 ARZXY2_RS08775 b712193fcba1cca0daec348f805e4fd8 339 Gene3D G3DSA:3.40.50.720 6 182 4.1E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 24 420 50.18 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 77 392 3.5E-46 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 SUPERFAMILY SSF53686 29 418 1.83E-139 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 Gene3D G3DSA:3.40.50.1100 121 200 5.1E-21 T 09-03-2017 ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 104 118 - T 09-03-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 31 417 1.9E-183 T 09-03-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 Gene3D G3DSA:3.40.50.1100 201 421 1.9E-95 T 09-03-2017 ARZXY2_RS10265 28cb2646614a6c464db2fabf2614d066 458 PIRSF PIRSF001413 23 425 1.3E-157 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 ARZXY2_RS08390 0a87e0df14fb51b841b0850ff95c04f2 133 PIRSF PIRSF017385 1 133 4.9E-46 T 09-03-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 ARZXY2_RS08390 0a87e0df14fb51b841b0850ff95c04f2 133 Pfam PF12270 Cytochrome c oxidase subunit IV 2 132 6.6E-52 T 09-03-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 Pfam PF00990 Diguanylate cyclase, GGDEF domain 85 239 5.3E-41 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 SUPERFAMILY SSF55073 90 245 1.1E-41 T 09-03-2017 IPR029787 Nucleotide cyclase ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 Gene3D G3DSA:3.30.70.270 87 249 4.4E-51 T 09-03-2017 ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 SUPERFAMILY SSF141868 260 512 5.49E-80 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 81 244 3.2E-39 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 SMART SM00052 254 503 2.6E-94 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 SMART SM00267 74 244 9.5E-55 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 Gene3D G3DSA:3.20.20.450 257 510 9.4E-89 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS02335 e3ff690f2200c47d57cb449987186786 518 Pfam PF00563 EAL domain 260 498 1.3E-69 T 09-03-2017 IPR001633 EAL domain ARZXY2_RS18640 d9ac398299b3751fa5e1b0599b6db5c1 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 10 191 6.1E-46 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS18640 d9ac398299b3751fa5e1b0599b6db5c1 192 SMART SM00855 9 153 2.2E-21 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS18640 d9ac398299b3751fa5e1b0599b6db5c1 192 SUPERFAMILY SSF53254 9 191 1.22E-47 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS18640 d9ac398299b3751fa5e1b0599b6db5c1 192 Gene3D G3DSA:3.40.50.1240 7 188 1.4E-45 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS18640 d9ac398299b3751fa5e1b0599b6db5c1 192 PIRSF PIRSF000709 1 175 4.0E-9 T 09-03-2017 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 Gene3D G3DSA:3.40.50.300 4 154 9.1E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 SUPERFAMILY SSF46894 821 882 3.74E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 Pfam PF13191 AAA ATPase domain 6 134 4.5E-11 T 09-03-2017 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 Gene3D G3DSA:1.10.10.10 822 882 2.8E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 SUPERFAMILY SSF52540 4 216 1.19E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 Pfam PF00196 Bacterial regulatory proteins, luxR family 829 879 1.6E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 844 860 8.5E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 830 844 8.5E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 860 872 8.5E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS12750 bb6032f4f458ed3df982e1632508d900 886 SMART SM00421 827 884 6.0E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 105 118 - T 09-03-2017 IPR033135 ClpP, histidine active site ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 PRINTS PR00127 Clp protease catalytic subunit P signature 12 27 1.4E-45 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 PRINTS PR00127 Clp protease catalytic subunit P signature 52 72 1.4E-45 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 PRINTS PR00127 Clp protease catalytic subunit P signature 83 100 1.4E-45 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 PRINTS PR00127 Clp protease catalytic subunit P signature 104 123 1.4E-45 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 PRINTS PR00127 Clp protease catalytic subunit P signature 161 180 1.4E-45 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 SUPERFAMILY SSF52096 12 183 1.67E-65 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 Gene3D G3DSA:3.90.226.10 13 184 6.8E-77 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 186 38.013 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07590 47ba33ea68818e058a5c5ca3e5628c0a 204 Pfam PF00574 Clp protease 11 184 5.5E-76 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Gene3D G3DSA:1.10.490.10 2 145 5.2E-41 T 09-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 SUPERFAMILY SSF46458 1 148 7.15E-31 T 09-03-2017 IPR009050 Globin-like ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Gene3D G3DSA:3.40.50.80 255 381 8.3E-22 T 09-03-2017 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 PRINTS PR00409 Phthalate dioxygenase reductase family signature 261 280 1.1E-8 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 PRINTS PR00409 Phthalate dioxygenase reductase family signature 345 353 1.1E-8 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 PRINTS PR00409 Phthalate dioxygenase reductase family signature 190 202 1.1E-8 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 PRINTS PR00409 Phthalate dioxygenase reductase family signature 239 253 1.1E-8 T 09-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Pfam PF00042 Globin 10 105 4.0E-7 T 09-03-2017 IPR000971 Globin GO:0019825|GO:0020037 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 SUPERFAMILY SSF52343 254 379 7.99E-25 T 09-03-2017 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 SUPERFAMILY SSF63380 149 255 4.48E-21 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Pfam PF00970 Oxidoreductase FAD-binding domain 157 251 8.7E-10 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Pfam PF00175 Oxidoreductase NAD-binding domain 264 359 3.0E-4 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 ARZXY2_RS15100 946b77243fde91cb9ceee13b721e3587 385 Gene3D G3DSA:2.40.30.10 153 253 7.3E-23 T 09-03-2017 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1126 1263 1.5E-43 T 09-03-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 149 377 5.1E-52 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Gene3D G3DSA:3.40.50.970 486 854 3.5E-79 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 13 46 3.9E-9 T 09-03-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Gene3D G3DSA:3.30.559.10 133 377 1.9E-53 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 SUPERFAMILY SSF52777 137 377 1.33E-56 T 09-03-2017 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Pfam PF00676 Dehydrogenase E1 component 532 852 2.0E-59 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Pfam PF02779 Transketolase, pyrimidine binding domain 928 1120 1.9E-54 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 SMART SM00861 928 1121 1.4E-48 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 406 1263 0.0 T 09-03-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 Gene3D G3DSA:3.40.50.970 948 1132 2.4E-19 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 PIRSF PIRSF000157 4 1265 0.0 T 09-03-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 SUPERFAMILY SSF52518 478 863 3.29E-87 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05055 61e6d457ad44b0280a6dd188eafd5ec0 1266 SUPERFAMILY SSF52518 916 1126 6.77E-45 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02750 03aaca439b098bd91d02584248fb8e8a 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 282 1.5E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02750 03aaca439b098bd91d02584248fb8e8a 290 Gene3D G3DSA:1.10.3720.10 17 278 4.0E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02750 03aaca439b098bd91d02584248fb8e8a 290 SUPERFAMILY SSF161098 19 289 9.35E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05540 3ad9c96898994f16d36a9a68130a6f04 282 SUPERFAMILY SSF56529 100 273 4.58E-53 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS05540 3ad9c96898994f16d36a9a68130a6f04 282 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 96 272 4.0E-50 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS05540 3ad9c96898994f16d36a9a68130a6f04 282 Gene3D G3DSA:3.90.850.10 100 273 4.4E-56 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 ProSitePatterns PS00331 Malic enzymes signature. 233 249 - T 09-03-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 SUPERFAMILY SSF53223 86 235 2.09E-54 T 09-03-2017 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 Pfam PF00390 Malic enzyme, N-terminal domain 93 225 1.1E-26 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 SUPERFAMILY SSF51735 237 461 6.01E-69 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 SMART SM01274 92 225 1.8E-78 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 PRINTS PR00072 Malic enzyme signature 264 280 1.2E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 PRINTS PR00072 Malic enzyme signature 154 176 1.2E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 PRINTS PR00072 Malic enzyme signature 233 249 1.2E-7 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 PIRSF PIRSF000106 18 464 2.7E-80 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 Gene3D G3DSA:3.40.50.720 235 458 3.0E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 1.0E-20 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 Gene3D G3DSA:3.40.50.10380 91 234 2.8E-52 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 ARZXY2_RS01570 152498660865da719a5688b85cfe054f 464 SMART SM00919 237 459 7.5E-110 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Pfam PF02803 Thiolase, C-terminal domain 277 395 2.5E-39 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 SUPERFAMILY SSF53901 8 275 5.51E-78 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Gene3D G3DSA:3.40.47.10 8 128 9.2E-68 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Gene3D G3DSA:3.40.47.10 199 280 9.2E-68 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 PIRSF PIRSF000429 3 397 1.1E-110 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Pfam PF00108 Thiolase, N-terminal domain 9 267 2.6E-89 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 09-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 SUPERFAMILY SSF53901 278 397 1.92E-32 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 395 1.2E-125 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Gene3D G3DSA:3.40.47.10 282 395 7.8E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 Gene3D G3DSA:3.40.47.10 149 198 7.8E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03445 953a7aa267f77fddac78677f62de992c 398 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 ARZXY2_RS11435 ca5605899fc5be46652acab00bfe28d7 411 Pfam PF07786 Protein of unknown function (DUF1624) 21 229 4.3E-12 T 09-03-2017 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 ARZXY2_RS00335 7a92d851d5afcf4c25659f84472c6d00 191 Gene3D G3DSA:2.70.40.10 2 183 1.4E-67 T 09-03-2017 IPR029054 dUTPase-like ARZXY2_RS00335 7a92d851d5afcf4c25659f84472c6d00 191 SUPERFAMILY SSF51283 3 183 1.64E-56 T 09-03-2017 IPR029054 dUTPase-like ARZXY2_RS00335 7a92d851d5afcf4c25659f84472c6d00 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.153 T 09-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 ARZXY2_RS00335 7a92d851d5afcf4c25659f84472c6d00 191 Pfam PF00692 dUTPase 69 178 8.4E-11 T 09-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 ARZXY2_RS00335 7a92d851d5afcf4c25659f84472c6d00 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 4.2E-65 T 09-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Gene3D G3DSA:3.40.50.740 120 193 2.5E-52 T 09-03-2017 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Gene3D G3DSA:3.40.50.740 405 646 2.5E-52 T 09-03-2017 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 SUPERFAMILY SSF53706 58 646 1.27E-138 T 09-03-2017 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Pfam PF00384 Molybdopterin oxidoreductase 120 550 8.8E-28 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Gene3D G3DSA:2.40.40.20 659 772 5.3E-11 T 09-03-2017 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 772 7.5E-288 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 SUPERFAMILY SSF50692 657 773 1.57E-18 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Pfam PF01568 Molydopterin dinucleotide binding domain 660 766 1.9E-12 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 PIRSF PIRSF000144 3 773 0.0 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 ARZXY2_RS16470 ae6fed4375d186e7a63acb0269ff47ab 773 Gene3D G3DSA:3.40.228.10 194 404 1.8E-53 T 09-03-2017 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 PIRSF PIRSF000484 1 428 8.4E-95 T 09-03-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 1 371 4.1E-122 T 09-03-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 147 334 6.8E-5 T 09-03-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 Gene3D G3DSA:3.20.140.10 1 359 4.1E-86 T 09-03-2017 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 SUPERFAMILY SSF54675 1 128 4.71E-41 T 09-03-2017 ARZXY2_RS05360 de18dd4ab54ec845390a01580a0bcd04 429 SUPERFAMILY SSF51690 130 427 3.24E-83 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 ARZXY2_RS11575 91e7321ad50b751e290a313824662ef4 335 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 49 295 9.1E-35 T 09-03-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 ARZXY2_RS11575 91e7321ad50b751e290a313824662ef4 335 SUPERFAMILY SSF56112 55 294 9.69E-16 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS17650 198d199e82561c5bcde11a9c4c5736d8 367 Gene3D G3DSA:1.10.3720.10 73 361 7.1E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17650 198d199e82561c5bcde11a9c4c5736d8 367 SUPERFAMILY SSF161098 84 353 1.44E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17650 198d199e82561c5bcde11a9c4c5736d8 367 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 75 361 6.3E-83 T 09-03-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 ARZXY2_RS17650 198d199e82561c5bcde11a9c4c5736d8 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 365 8.1E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04765 11320dde741f3b5ced6c554a7c815049 309 SUPERFAMILY SSF53271 222 292 3.28E-13 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS04765 11320dde741f3b5ced6c554a7c815049 309 SUPERFAMILY SSF53271 113 192 3.28E-13 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS04765 11320dde741f3b5ced6c554a7c815049 309 Gene3D G3DSA:3.40.50.2020 102 293 1.1E-19 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS04765 11320dde741f3b5ced6c554a7c815049 309 Pfam PF00156 Phosphoribosyl transferase domain 236 291 1.6E-7 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 Gene3D G3DSA:3.40.50.720 3 254 1.3E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 7.7E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 253 6.2E-59 T 09-03-2017 ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 TIGRFAM TIGR02415 23BDH: acetoin reductases 3 255 4.6E-101 T 09-03-2017 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS00765 d45f76a0bf2e95a7541264c827f54842 256 SUPERFAMILY SSF51735 3 254 1.13E-78 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 95 124 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 212 240 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 167 196 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 299 316 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 129 158 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 PRINTS PR00142 RecA protein signature 245 274 2.3E-84 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 Gene3D G3DSA:3.30.250.10 270 328 7.9E-27 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 Gene3D G3DSA:3.40.50.300 28 269 5.2E-84 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 9.8E-171 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 ProSitePatterns PS00321 recA signature. 215 223 - T 09-03-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 Pfam PF00154 recA bacterial DNA recombination protein 9 270 5.8E-142 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 SMART SM00382 59 230 3.1E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 Hamap MF_00268 Protein RecA [recA]. 7 331 52.123 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 SUPERFAMILY SSF52540 6 269 4.28E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11385 8acb332f7933145753ef06eb9e93695f 346 SUPERFAMILY SSF54752 270 328 1.57E-19 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal ARZXY2_RS12705 a8aff374d1c708355db66963575c3f4e 268 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 233 5.2E-23 T 09-03-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 Gene3D G3DSA:1.20.1250.20 269 449 9.9E-10 T 09-03-2017 ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 Gene3D G3DSA:1.20.1250.20 15 188 4.0E-20 T 09-03-2017 ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 SUPERFAMILY SSF103473 9 197 9.16E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 SUPERFAMILY SSF103473 252 452 9.16E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 Pfam PF07690 Major Facilitator Superfamily 24 333 9.2E-19 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 9.1E-6 T 09-03-2017 ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 9.1E-6 T 09-03-2017 ARZXY2_RS01005 c0582d17048d842ca9b1cbe25e6184eb 466 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 9.1E-6 T 09-03-2017 ARZXY2_RS10425 3ef1521bfa8458c0942dcb48c251b41a 345 Pfam PF03969 AFG1-like ATPase 43 220 2.1E-41 T 09-03-2017 IPR005654 ATPase, AFG1-like GO:0005524 ARZXY2_RS10425 3ef1521bfa8458c0942dcb48c251b41a 345 SUPERFAMILY SSF52540 71 184 3.97E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10425 3ef1521bfa8458c0942dcb48c251b41a 345 Gene3D G3DSA:3.40.50.300 16 204 1.3E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF56784 451 699 2.2E-53 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF56784 392 412 2.2E-53 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 168 680 6.9E-86 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 551 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 629 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 394 408 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 245 259 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 613 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 530 2.5E-27 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 396 402 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Gene3D G3DSA:3.40.50.1000 522 662 2.3E-50 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Gene3D G3DSA:3.40.50.1000 367 408 2.3E-50 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Pfam PF00702 haloacid dehalogenase-like hydrolase 390 607 6.2E-45 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF81653 198 295 7.85E-25 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Gene3D G3DSA:3.40.1110.10 409 521 1.0E-23 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 114 703 2.6E-171 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Gene3D G3DSA:2.70.150.10 136 295 4.4E-27 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 132 701 1.7E-172 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF81665 296 388 8.11E-13 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF81665 643 674 8.11E-13 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 SUPERFAMILY SSF81665 140 199 8.11E-13 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 Pfam PF00122 E1-E2 ATPase 166 385 4.6E-58 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 188 206 3.2E-9 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 377 392 3.2E-9 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 117 136 3.2E-9 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 667 681 3.2E-9 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 571 588 3.2E-9 T 09-03-2017 ARZXY2_RS10125 6fae1a30980f71f830b5419325309e24 713 PRINTS PR00943 Copper-transporting ATPase signature 628 642 3.2E-9 T 09-03-2017 ARZXY2_RS03010 2f4b3c645535a7530db7a15dd557edbd 289 Pfam PF01435 Peptidase family M48 72 283 2.1E-34 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 ARZXY2_RS03010 2f4b3c645535a7530db7a15dd557edbd 289 Gene3D G3DSA:3.30.2010.10 65 154 2.4E-30 T 09-03-2017 ARZXY2_RS03010 2f4b3c645535a7530db7a15dd557edbd 289 Hamap MF_00188 Protease HtpX [htpX]. 7 283 26.638 T 09-03-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 ARZXY2_RS08075 7de87618976b2e4136802757b27f422b 284 Gene3D G3DSA:3.40.192.10 3 111 6.1E-35 T 09-03-2017 ARZXY2_RS08075 7de87618976b2e4136802757b27f422b 284 SUPERFAMILY SSF53223 3 106 3.05E-24 T 09-03-2017 ARZXY2_RS08075 7de87618976b2e4136802757b27f422b 284 Gene3D G3DSA:3.40.50.720 112 271 3.7E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08075 7de87618976b2e4136802757b27f422b 284 SUPERFAMILY SSF51735 107 269 8.04E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08075 7de87618976b2e4136802757b27f422b 284 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 90 4.5E-24 T 09-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 8 160 27.063 T 09-03-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 Gene3D G3DSA:3.10.50.30 82 162 4.3E-16 T 09-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 SUPERFAMILY SSF54534 86 159 1.7E-11 T 09-03-2017 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 09-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 23 54 - T 09-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 PIRSF PIRSF006092 5 163 3.3E-34 T 09-03-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 Pfam PF03449 Transcription elongation factor, N-terminal 11 80 7.4E-27 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 SUPERFAMILY SSF46557 10 83 1.44E-23 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 88 160 2.1E-13 T 09-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 ARZXY2_RS13015 75ba88c72a1c8421ecdbe78e92de62a7 164 Gene3D G3DSA:1.10.287.180 10 80 7.2E-28 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 SUPERFAMILY SSF100934 484 583 1.47E-13 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.30.30.30 39 100 1.6E-16 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 580 2.2E-267 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 SUPERFAMILY SSF53067 163 359 1.49E-58 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 SUPERFAMILY SSF100920 361 517 6.67E-61 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 SUPERFAMILY SSF53067 1 159 1.74E-57 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:1.20.1270.10 510 580 6.6E-22 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 615 35.013 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.30.420.40 295 337 6.0E-30 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.30.420.40 167 206 6.0E-30 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Pfam PF00012 Hsp70 protein 4 580 4.2E-231 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:2.60.34.10 367 509 1.1E-72 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 174 184 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 342 362 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 114 134 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 365 384 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 446 462 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 PRINTS PR00301 70kDa heat shock protein signature 310 326 6.9E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.90.640.10 207 291 1.3E-25 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.30.420.40 4 38 2.6E-56 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 Gene3D G3DSA:3.30.420.40 101 166 2.6E-56 T 09-03-2017 ARZXY2_RS00720 ab6efca6de1dddac94ce2bec692fa923 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 ARZXY2_RS16985 5c8a21635323d2bae9fe48ed1efbe316 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 4.6E-85 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS16985 5c8a21635323d2bae9fe48ed1efbe316 366 SUPERFAMILY SSF51395 2 363 4.4E-116 T 09-03-2017 ARZXY2_RS16985 5c8a21635323d2bae9fe48ed1efbe316 366 Gene3D G3DSA:3.20.20.70 3 363 2.6E-123 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS18220 75c7a5e07991498be40f1bdf5983a0fe 73 Gene3D G3DSA:1.10.260.40 3 66 1.4E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS18220 75c7a5e07991498be40f1bdf5983a0fe 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 3.3E-18 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS18220 75c7a5e07991498be40f1bdf5983a0fe 73 SMART SM00530 6 62 0.0034 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS18220 75c7a5e07991498be40f1bdf5983a0fe 73 SUPERFAMILY SSF47413 2 68 4.02E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 SUPERFAMILY SSF46785 4 64 3.63E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 3.9E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 Pfam PF01037 Lrp/AsnC ligand binding domain 70 140 2.3E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.3E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.3E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.3E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 SMART SM00344 4 110 9.4E-23 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 Gene3D G3DSA:3.30.70.920 56 142 3.2E-19 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 SUPERFAMILY SSF54909 64 149 1.09E-15 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS11735 beebdf6cc4fb7206cd9a692e9dbbef93 156 Gene3D G3DSA:1.10.10.10 2 47 8.6E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 SMART SM00862 158 241 1.7E-20 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 241 9.5E-18 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 Gene3D G3DSA:1.10.10.10 136 244 3.5E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 Pfam PF00072 Response regulator receiver domain 8 116 5.9E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 Gene3D G3DSA:3.40.50.2300 8 124 2.3E-37 T 09-03-2017 ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 SUPERFAMILY SSF46894 134 242 3.12E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 SUPERFAMILY SSF52172 8 126 3.98E-37 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS13920 0db0ff00bfd174bb100447a1a7552a3d 248 SMART SM00448 4 115 1.7E-38 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 439 503 4.7E-7 T 09-03-2017 IPR018905 Alpha-galactosidase, NEW3 domain ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 SUPERFAMILY SSF50939 63 422 4.21E-91 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 Gene3D G3DSA:2.60.40.10 422 523 8.8E-33 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 Pfam PF13088 BNR repeat-like domain 83 401 2.5E-26 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 791 817 9.3E-4 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS15885 df3cb28afe0c2b5c33e2800e25c71a7d 990 Gene3D G3DSA:2.120.10.10 55 418 4.1E-85 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS07660 b7c2b5f06f45e569d28cde87502fca0a 1123 SMART SM00316 427 506 1.0E-7 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS07660 b7c2b5f06f45e569d28cde87502fca0a 1123 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 404 807 1.6E-150 T 09-03-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 ARZXY2_RS07660 b7c2b5f06f45e569d28cde87502fca0a 1123 Pfam PF10150 Ribonuclease E/G family 508 779 7.1E-104 T 09-03-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 ARZXY2_RS07660 b7c2b5f06f45e569d28cde87502fca0a 1123 SUPERFAMILY SSF50249 429 512 1.09E-16 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07660 b7c2b5f06f45e569d28cde87502fca0a 1123 Gene3D G3DSA:2.40.50.140 422 512 3.2E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 Pfam PF00817 impB/mucB/samB family 14 158 1.4E-20 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 SUPERFAMILY SSF56672 11 246 1.6E-53 T 09-03-2017 ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 Pfam PF13438 Domain of unknown function (DUF4113) 384 432 2.0E-14 T 09-03-2017 IPR025188 Domain of unknown function DUF4113 ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 Gene3D G3DSA:1.10.150.20 178 250 2.2E-18 T 09-03-2017 ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 Gene3D G3DSA:3.30.70.270 81 164 3.7E-14 T 09-03-2017 ARZXY2_RS06175 899935b4aae2bd9f79a14203427826d7 434 Pfam PF11799 impB/mucB/samB family C-terminal domain 253 364 1.8E-10 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS19025 10d042036cf68653434e12c44df01b80 463 PIRSF PIRSF002746 10 463 1.1E-145 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS19025 10d042036cf68653434e12c44df01b80 463 Pfam PF02447 GntP family permease 16 457 8.0E-124 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS19025 10d042036cf68653434e12c44df01b80 463 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 460 4.7E-112 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00397 Sirohaem Fe-binding site signature 696 714 3.0E-6 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00397 Sirohaem Fe-binding site signature 653 671 3.0E-6 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 SUPERFAMILY SSF55124 521 658 2.45E-27 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PIRSF PIRSF037149 6 853 0.0 T 09-03-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Gene3D G3DSA:3.50.50.60 240 326 1.1E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Gene3D G3DSA:3.50.50.60 116 239 5.7E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Pfam PF04324 BFD-like [2Fe-2S] binding domain 432 488 6.9E-9 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Pfam PF04324 BFD-like [2Fe-2S] binding domain 508 550 4.8E-6 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Gene3D G3DSA:3.50.50.60 8 115 4.7E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 298 6.3E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 696 712 - T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Gene3D G3DSA:3.30.413.10 649 780 8.5E-33 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 8.1E-22 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 8.1E-22 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 8.1E-22 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 8.1E-22 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 8.1E-22 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 649 770 5.4E-17 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 SUPERFAMILY SSF51905 7 324 9.72E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 14 818 1.2E-272 T 09-03-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 SUPERFAMILY SSF56014 650 824 3.79E-49 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 577 638 3.0E-11 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 9.4E-11 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 9.4E-11 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 9.4E-11 T 09-03-2017 ARZXY2_RS12585 5ebb8bbb90032c91af489594d40d0b35 874 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 183 9.4E-11 T 09-03-2017 ARZXY2_RS11680 10cf12bec0ae26899f404822d2c054e9 166 Pfam PF01575 MaoC like domain 20 129 2.2E-22 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS11680 10cf12bec0ae26899f404822d2c054e9 166 SUPERFAMILY SSF54637 5 155 2.96E-44 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS11680 10cf12bec0ae26899f404822d2c054e9 166 Gene3D G3DSA:3.10.129.10 6 155 1.7E-41 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 Pfam PF13555 P-loop containing region of AAA domain 35 95 2.3E-22 T 09-03-2017 ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 Pfam PF13558 Putative exonuclease SbcCD, C subunit 988 1086 1.2E-19 T 09-03-2017 ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 Gene3D G3DSA:3.40.1140.10 33 120 2.8E-26 T 09-03-2017 ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 Gene3D G3DSA:3.40.1140.10 157 251 2.8E-26 T 09-03-2017 ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 SUPERFAMILY SSF52540 934 1096 7.03E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13500 23d0cb0b1c8bb4e78740fa7e84981a14 1141 SUPERFAMILY SSF52540 53 85 7.03E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 SUPERFAMILY SSF103473 19 279 1.57E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 SUPERFAMILY SSF103473 307 465 1.57E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 Gene3D G3DSA:1.20.1250.20 248 460 9.8E-14 T 09-03-2017 ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 Pfam PF00083 Sugar (and other) transporter 308 460 8.8E-12 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 Pfam PF00083 Sugar (and other) transporter 23 236 2.2E-27 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 Gene3D G3DSA:1.20.1250.20 21 225 2.2E-19 T 09-03-2017 ARZXY2_RS12530 d5243a2da29d61ce82571bc0b407a5ed 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 332 349 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 SUPERFAMILY SSF51604 112 353 1.44E-63 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 Gene3D G3DSA:3.20.20.120 120 353 5.1E-68 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 Gene3D G3DSA:3.30.390.10 4 119 3.6E-25 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 124 1.7E-11 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 SMART SM00922 143 240 1.0E-29 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 Pfam PF13378 Enolase C-terminal domain-like 145 353 3.2E-59 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS01980 ed738652b9d4b88bc2e5010e68610de4 375 SUPERFAMILY SSF54826 4 125 6.9E-21 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS10080 a6eb6a1431ad925ddf45f23b5eaff0f3 429 Gene3D G3DSA:3.40.190.10 177 365 1.2E-29 T 09-03-2017 ARZXY2_RS10080 a6eb6a1431ad925ddf45f23b5eaff0f3 429 SUPERFAMILY SSF53850 50 427 9.39E-51 T 09-03-2017 ARZXY2_RS10080 a6eb6a1431ad925ddf45f23b5eaff0f3 429 Pfam PF01547 Bacterial extracellular solute-binding protein 62 350 1.1E-21 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS10080 a6eb6a1431ad925ddf45f23b5eaff0f3 429 Gene3D G3DSA:3.40.190.10 50 176 1.8E-12 T 09-03-2017 ARZXY2_RS08885 a0ac77e1f7aa16fc2c8ffcd105254147 269 SUPERFAMILY SSF75217 104 266 5.95E-39 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS08885 a0ac77e1f7aa16fc2c8ffcd105254147 269 Pfam PF00588 SpoU rRNA Methylase family 121 262 1.4E-31 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ARZXY2_RS08885 a0ac77e1f7aa16fc2c8ffcd105254147 269 Gene3D G3DSA:3.30.1330.30 6 106 3.1E-16 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS08885 a0ac77e1f7aa16fc2c8ffcd105254147 269 SUPERFAMILY SSF55315 5 106 4.94E-15 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like ARZXY2_RS08885 a0ac77e1f7aa16fc2c8ffcd105254147 269 Gene3D G3DSA:3.40.1280.10 117 266 9.5E-53 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 SMART SM00420 7 59 8.6E-10 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 Pfam PF08220 DeoR-like helix-turn-helix domain 7 58 6.1E-13 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 SUPERFAMILY SSF46785 5 60 2.73E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 3.7E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 3.7E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 Gene3D G3DSA:3.40.50.1360 77 213 9.3E-12 T 09-03-2017 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 Pfam PF00455 DeoR C terminal sensor domain 77 232 3.1E-42 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 Gene3D G3DSA:1.10.10.10 1 52 3.7E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 SUPERFAMILY SSF100950 76 236 5.98E-25 T 09-03-2017 ARZXY2_RS10190 eba5b1678f3d6708264cd030aa23b9eb 255 SMART SM01134 73 234 1.6E-57 T 09-03-2017 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 SUPERFAMILY SSF51735 3 132 5.84E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 SUPERFAMILY SSF116726 140 213 4.84E-5 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 PRINTS PR00335 TrkA potassium uptake protein signature 20 34 1.8E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 PRINTS PR00335 TrkA potassium uptake protein signature 3 17 1.8E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 PRINTS PR00335 TrkA potassium uptake protein signature 61 71 1.8E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 PRINTS PR00335 TrkA potassium uptake protein signature 74 88 1.8E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 Gene3D G3DSA:3.40.50.720 3 129 7.2E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10530 e4c660d53dea60d74bc73bd31675c7af 223 Pfam PF02254 TrkA-N domain 4 117 2.3E-25 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 ARZXY2_RS15670 bf47c68b426386586468ba480b4abd98 335 PIRSF PIRSF017082 4 335 1.3E-92 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 ARZXY2_RS15670 bf47c68b426386586468ba480b4abd98 335 SUPERFAMILY SSF53850 51 244 1.09E-9 T 09-03-2017 ARZXY2_RS15670 bf47c68b426386586468ba480b4abd98 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 334 1.2E-25 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Gene3D G3DSA:1.10.220.30 58 174 1.7E-22 T 09-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Gene3D G3DSA:1.10.220.30 182 320 2.4E-32 T 09-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Pfam PF01706 FliG C-terminal domain 205 310 3.2E-31 T 09-03-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 SUPERFAMILY SSF48029 99 311 6.93E-51 T 09-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Gene3D G3DSA:1.10.220.30 1 48 1.0E-7 T 09-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 319 5.7E-77 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Pfam PF14841 FliG middle domain 100 174 1.6E-21 T 09-03-2017 IPR032779 Flagellar motor switch protein FliG, middle domain ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 SUPERFAMILY SSF48029 2 100 1.26E-12 T 09-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 Pfam PF14842 FliG N-terminal domain 1 91 1.1E-16 T 09-03-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 19 45 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 235 255 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 182 207 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 213 233 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 99 122 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS14535 4a8df5dfa9a83673c5f5574440c54ce6 321 PRINTS PR00954 Flagellar motor switch protein FliG signature 259 285 2.4E-43 T 09-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 Gene3D G3DSA:3.90.1150.10 8 57 2.2E-14 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 Gene3D G3DSA:3.90.1150.10 312 414 2.2E-14 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 Pfam PF00202 Aminotransferase class-III 23 409 1.7E-59 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 Gene3D G3DSA:3.40.640.10 59 308 1.1E-50 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 SUPERFAMILY SSF53383 11 412 2.84E-71 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS01315 06b199ee0cf29740cacf26eea26f20ef 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 226 263 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Gene3D G3DSA:3.30.70.80 39 116 3.3E-5 T 09-03-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 228 238 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 632 692 5.1E-8 T 09-03-2017 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 482 542 1.2E-10 T 09-03-2017 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 PRINTS PR00723 Subtilisin serine protease family (S8) signature 224 237 1.4E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 PRINTS PR00723 Subtilisin serine protease family (S8) signature 405 421 1.4E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 PRINTS PR00723 Subtilisin serine protease family (S8) signature 159 178 1.4E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 SUPERFAMILY SSF52743 228 467 3.14E-71 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 SUPERFAMILY SSF52743 145 199 3.14E-71 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 164 174 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Gene3D G3DSA:2.130.10.130 567 705 1.3E-12 T 09-03-2017 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Pfam PF00082 Subtilase family 159 454 8.2E-46 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 SUPERFAMILY SSF69318 474 724 2.22E-41 T 09-03-2017 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 Gene3D G3DSA:3.40.50.200 117 464 3.1E-84 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS02700 18dc4a69e703e7890821650a8caddaf5 728 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 406 416 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site ARZXY2_RS04960 f48241dcbecebc34d254b714994458fa 304 PIRSF PIRSF003097 1 304 4.3E-73 T 09-03-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 ARZXY2_RS04960 f48241dcbecebc34d254b714994458fa 304 Pfam PF02687 FtsX-like permease family 185 302 4.7E-11 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS14740 f84a67fcdb47ffc130e925ce099a8c5f 404 Pfam PF00999 Sodium/hydrogen exchanger family 10 380 1.2E-39 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ARZXY2_RS02050 0e6d42e32cae98140a5b6b571041bb8a 426 Pfam PF05977 Transmembrane secretion effector 27 418 4.9E-48 T 09-03-2017 IPR010290 Transmembrane secretion effector ARZXY2_RS02050 0e6d42e32cae98140a5b6b571041bb8a 426 Gene3D G3DSA:1.20.1250.20 36 216 5.0E-20 T 09-03-2017 ARZXY2_RS02050 0e6d42e32cae98140a5b6b571041bb8a 426 Gene3D G3DSA:1.20.1250.20 248 423 4.2E-10 T 09-03-2017 ARZXY2_RS02050 0e6d42e32cae98140a5b6b571041bb8a 426 SUPERFAMILY SSF103473 31 424 1.7E-42 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 SUPERFAMILY SSF51735 6 163 3.95E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 SUPERFAMILY SSF48179 167 292 5.55E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 09-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 291 3.4E-29 T 09-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 Gene3D G3DSA:1.10.1040.10 167 293 7.8E-34 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 Gene3D G3DSA:3.40.50.720 3 164 2.2E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 161 3.3E-30 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS17445 2f3b8c7b822f5494511b1680833e2bb5 299 PIRSF PIRSF000103 1 299 4.1E-58 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Gene3D G3DSA:3.40.50.300 8 293 5.7E-106 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Pfam PF00009 Elongation factor Tu GTP binding domain 11 287 2.0E-68 T 09-03-2017 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Gene3D G3DSA:3.30.70.870 413 487 6.9E-38 T 09-03-2017 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SUPERFAMILY SSF54980 411 488 1.15E-24 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 PRINTS PR00315 GTP-binding elongation factor signature 132 141 2.0E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.0E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.0E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.0E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Pfam PF14492 Elongation Factor G, domain II 411 485 1.9E-34 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Hamap MF_00054_B Elongation factor G [fusA]. 8 701 108.908 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Gene3D G3DSA:3.30.230.10 491 608 1.5E-45 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SUPERFAMILY SSF52540 8 288 6.21E-110 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SUPERFAMILY SSF54980 613 700 6.83E-30 T 09-03-2017 IPR009022 Elongation factor G, III-V domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 2.4E-37 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Gene3D G3DSA:2.40.30.10 313 412 1.5E-35 T 09-03-2017 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Pfam PF03764 Elongation factor G, domain IV 486 608 4.9E-46 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SMART SM00838 610 697 6.6E-58 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 701 0.0 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SUPERFAMILY SSF50447 271 411 9.84E-33 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Pfam PF03144 Elongation factor Tu domain 2 331 398 3.9E-15 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SUPERFAMILY SSF54211 486 609 3.54E-39 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Pfam PF00679 Elongation factor G C-terminus 610 696 1.5E-29 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 SMART SM00889 487 608 3.8E-69 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 ARZXY2_RS03470 50c7d0b557934f2209198ac180d36c87 704 Gene3D G3DSA:3.30.70.240 609 695 1.5E-33 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS15760 abf6f411f0ddffb83ea8946610fd70c4 315 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 13 268 33.817 T 09-03-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 ARZXY2_RS15760 abf6f411f0ddffb83ea8946610fd70c4 315 Pfam PF00149 Calcineurin-like phosphoesterase 15 211 2.7E-13 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 ARZXY2_RS15760 abf6f411f0ddffb83ea8946610fd70c4 315 SUPERFAMILY SSF56300 12 266 2.69E-49 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS15760 abf6f411f0ddffb83ea8946610fd70c4 315 Gene3D G3DSA:3.60.21.10 11 262 1.2E-30 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 36.287 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 09-03-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 5.0E-67 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 252 8.2E-72 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 Gene3D G3DSA:3.40.1180.10 10 252 3.0E-89 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS12985 1b8c04b2e07508ce8fc85367edf5c474 253 SUPERFAMILY SSF64005 19 247 1.44E-74 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 SUPERFAMILY SSF48256 9 424 1.96E-154 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 Pfam PF00285 Citrate synthase, C-terminal domain 47 413 3.0E-132 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 220 235 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 361 377 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 242 270 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 298 318 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 381 395 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PRINTS PR00143 Citrate synthase signature 166 179 2.1E-52 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 Gene3D G3DSA:1.10.580.10 53 282 4.2E-90 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 424 1.8E-182 T 09-03-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 Gene3D G3DSA:1.10.230.10 283 375 1.2E-38 T 09-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 ProSitePatterns PS00480 Citrate synthase signature. 305 317 - T 09-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 ARZXY2_RS04260 de14239bd422090998a9fed3c2cc2932 427 PIRSF PIRSF001369 38 427 1.6E-154 T 09-03-2017 IPR024176 Citrate synthase, bacterial-type ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.2E-31 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 Pfam PF00886 Ribosomal protein S16 9 67 5.2E-23 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.34 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 Gene3D G3DSA:3.30.1320.10 2 83 1.1E-32 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 09-03-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS07005 793105324e49ba2cfe14befc82a5ba55 136 SUPERFAMILY SSF54565 2 96 1.7E-33 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18975 7e90f313e90c5ee5c6d6de89c67b7bf0 207 SMART SM00934 2 202 3.0E-44 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS18975 7e90f313e90c5ee5c6d6de89c67b7bf0 207 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 206 1.9E-78 T 09-03-2017 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861 ARZXY2_RS18975 7e90f313e90c5ee5c6d6de89c67b7bf0 207 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 1 201 8.8E-28 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS18975 7e90f313e90c5ee5c6d6de89c67b7bf0 207 Gene3D G3DSA:3.20.20.70 1 206 4.6E-65 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS18975 7e90f313e90c5ee5c6d6de89c67b7bf0 207 SUPERFAMILY SSF51366 2 206 2.48E-40 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 Gene3D G3DSA:3.40.50.150 256 450 1.4E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 292 365 4.2E-5 T 09-03-2017 ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 374 449 5.4E-9 T 09-03-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 Gene3D G3DSA:2.40.50.140 19 88 1.0E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 SUPERFAMILY SSF50249 23 82 2.68E-9 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 383 414 - T 09-03-2017 IPR030390 RNA methyltransferase TrmA, active site ARZXY2_RS10520 667b66c69082e9fc88ecc629770ddb0a 454 SUPERFAMILY SSF53335 105 451 1.24E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 PIRSF PIRSF000362 7 484 4.7E-155 T 09-03-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 Gene3D G3DSA:3.40.50.720 338 481 1.6E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 Gene3D G3DSA:3.40.50.720 12 110 1.6E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 PRINTS PR00419 Adrenodoxin reductase family signature 159 173 1.6E-16 T 09-03-2017 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 PRINTS PR00419 Adrenodoxin reductase family signature 14 36 1.6E-16 T 09-03-2017 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 PRINTS PR00419 Adrenodoxin reductase family signature 88 98 1.6E-16 T 09-03-2017 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 192 3.1E-10 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 Gene3D G3DSA:3.50.50.60 111 337 1.1E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 SUPERFAMILY SSF51971 278 338 2.35E-55 T 09-03-2017 ARZXY2_RS02960 fe80470148177bbb743c5179c2a4cfb2 484 SUPERFAMILY SSF51971 12 225 2.35E-55 T 09-03-2017 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 SUPERFAMILY SSF56712 5 558 2.35E-73 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Pfam PF01751 Toprim domain 5 138 4.4E-9 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Pfam PF13101 Protein of unknown function (DUF3945) 749 782 0.026 T 09-03-2017 IPR025222 Protein of unknown function DUF3945 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Pfam PF01131 DNA topoisomerase 160 556 5.7E-49 T 09-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 SMART SM00437 265 519 6.0E-5 T 09-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Gene3D G3DSA:1.10.460.10 457 557 7.4E-10 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Gene3D G3DSA:1.10.460.10 165 221 7.4E-10 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Gene3D G3DSA:1.10.290.10 273 400 6.8E-9 T 09-03-2017 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 4.1E-7 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 388 404 4.1E-7 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 306 315 4.1E-7 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 102 115 4.1E-7 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 197 215 4.1E-7 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS05985 4b98d80ddc2b15eeeb1745d72518a6ac 805 Gene3D G3DSA:3.40.50.140 5 153 8.0E-23 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 Gene3D G3DSA:3.40.50.150 240 257 1.1E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 Gene3D G3DSA:3.40.50.150 292 366 1.1E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 Gene3D G3DSA:3.40.50.150 457 592 1.1E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 Pfam PF07669 Eco57I restriction-modification methylase 465 552 5.2E-7 T 09-03-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 310 2.7E-10 T 09-03-2017 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 498 522 2.7E-10 T 09-03-2017 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 465 477 2.7E-10 T 09-03-2017 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 238 254 2.7E-10 T 09-03-2017 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 468 474 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 SUPERFAMILY SSF53335 292 368 1.14E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 SUPERFAMILY SSF53335 122 257 1.14E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 SUPERFAMILY SSF53335 460 627 1.14E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05870 602fe3d1bc220ac0f65ebd5e203418b0 1160 SUPERFAMILY SSF53335 62 87 1.14E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 Gene3D G3DSA:3.40.50.300 180 344 1.0E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 1.8E-11 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 Gene3D G3DSA:3.40.50.300 386 512 1.1E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 410 432 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 2.3E-36 T 09-03-2017 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 SMART SM00487 178 353 7.0E-21 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 SUPERFAMILY SSF52540 149 345 4.04E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 SMART SM00490 423 500 2.0E-10 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 541 2.8E-48 T 09-03-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 SUPERFAMILY SSF52540 285 354 1.48E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 SUPERFAMILY SSF52540 387 531 1.48E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14270 ec6f580e8f398080f86a81e32407915c 554 Pfam PF13625 Helicase conserved C-terminal domain 6 134 2.3E-45 T 09-03-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 ProSitePatterns PS00211 ABC transporters family signature. 193 207 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 Pfam PF00005 ABC transporter 66 221 3.2E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 Gene3D G3DSA:3.40.50.300 42 289 7.7E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 SUPERFAMILY SSF52540 44 292 2.51E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 269 291 1.1E-9 T 09-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal ARZXY2_RS13070 373f9b03ea7bcf3b1c5fd030f527542a 340 SMART SM00382 70 323 1.3E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12950 e9c7f4ee4ee88a74bdac06fcf060c66b 228 Pfam PF14030 Protein of unknown function (DUF4245) 43 209 1.5E-44 T 09-03-2017 IPR025339 Protein of unknown function DUF4245 ARZXY2_RS00325 10190b5c0bd16fb26cf3efe3ada8b318 398 SUPERFAMILY SSF69318 170 351 1.1E-12 T 09-03-2017 ARZXY2_RS00325 10190b5c0bd16fb26cf3efe3ada8b318 398 SUPERFAMILY SSF55797 2 107 1.75E-10 T 09-03-2017 IPR014044 CAP domain ARZXY2_RS00325 10190b5c0bd16fb26cf3efe3ada8b318 398 Pfam PF00188 Cysteine-rich secretory protein family 1 92 9.8E-6 T 09-03-2017 IPR014044 CAP domain ARZXY2_RS00325 10190b5c0bd16fb26cf3efe3ada8b318 398 Gene3D G3DSA:2.130.10.130 128 325 6.5E-7 T 09-03-2017 ARZXY2_RS03230 c57b6275bd477a74db6340f958f5b60d 351 SUPERFAMILY SSF53850 64 264 2.62E-29 T 09-03-2017 ARZXY2_RS03230 c57b6275bd477a74db6340f958f5b60d 351 Gene3D G3DSA:3.40.190.10 124 248 1.7E-18 T 09-03-2017 ARZXY2_RS03230 c57b6275bd477a74db6340f958f5b60d 351 Pfam PF09084 NMT1/THI5 like 74 264 1.6E-23 T 09-03-2017 IPR015168 SsuA/THI5-like ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 Gene3D G3DSA:3.30.70.920 67 139 2.3E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 Pfam PF13404 AsnC-type helix-turn-helix domain 7 46 5.6E-8 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 SMART SM00344 6 109 0.0027 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 3.8E-9 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 SUPERFAMILY SSF54909 67 147 5.77E-12 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS15290 f47f8ba50d9b02f94de35380347cf184 330 Gene3D G3DSA:1.10.10.10 5 50 3.7E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Pfam PF00270 DEAD/DEAH box helicase 22 194 1.1E-17 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 SUPERFAMILY SSF52540 33 80 5.31E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Gene3D G3DSA:1.10.10.10 431 498 1.9E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 SMART SM00490 262 343 3.5E-25 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Gene3D G3DSA:3.40.50.300 8 211 1.3E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Pfam PF16124 RecQ zinc-binding 430 488 3.8E-14 T 09-03-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Gene3D G3DSA:1.10.10.10 367 429 1.1E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 14 367 1.2E-101 T 09-03-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Pfam PF00271 Helicase conserved C-terminal domain 240 342 1.2E-17 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 SMART SM00487 16 225 3.6E-28 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 Gene3D G3DSA:3.40.50.300 214 358 6.1E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14725 e63d3610470c7b0698fb91076834e5f3 564 SUPERFAMILY SSF52540 70 360 3.72E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10850 ed4a2691b3b284119a999b0170517b26 441 Pfam PF01098 Cell cycle protein 61 414 2.0E-90 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 ARZXY2_RS10850 ed4a2691b3b284119a999b0170517b26 441 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 60 414 1.4E-110 T 09-03-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Gene3D G3DSA:3.30.450.20 28 155 4.9E-17 T 09-03-2017 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 315 358 1.9E-11 T 09-03-2017 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Gene3D G3DSA:3.30.450.20 212 304 2.9E-8 T 09-03-2017 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SUPERFAMILY SSF55785 212 260 1.74E-6 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SMART SM00091 209 274 1.9E-7 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SUPERFAMILY SSF103190 35 164 2.67E-19 T 09-03-2017 IPR029151 Periplasmic sensor domain-like ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SUPERFAMILY SSF55874 381 511 7.6E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SUPERFAMILY SSF55890 317 385 7.19E-11 T 09-03-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 1.9E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 502 1.9E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 479 1.9E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Pfam PF17203 Single cache domain 3 32 165 1.1E-18 T 09-03-2017 IPR033463 Single cache domain 3 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Gene3D G3DSA:3.30.565.10 386 514 2.4E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Gene3D G3DSA:1.10.287.130 305 366 1.9E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Pfam PF00989 PAS fold 210 253 8.1E-6 T 09-03-2017 IPR013767 PAS fold GO:0006355 ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 SMART SM00387 412 522 1.9E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS15665 036c5801f3607141939b4be52ff7c4e6 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 514 9.0E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS10635 5da41716569a38005fd0476eb158af6b 332 Pfam PF01435 Peptidase family M48 118 221 1.8E-11 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 ARZXY2_RS10635 5da41716569a38005fd0476eb158af6b 332 Gene3D G3DSA:3.30.2010.10 137 195 1.2E-10 T 09-03-2017 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 Gene3D G3DSA:1.10.357.10 207 380 4.7E-26 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 9.8E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 9.8E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 SUPERFAMILY SSF46689 10 84 5.99E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 Pfam PF00440 Bacterial regulatory proteins, tetR family 213 259 9.9E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.2E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 ProSitePatterns PS01081 TetR-type HTH domain signature. 225 256 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 Gene3D G3DSA:1.10.357.10 3 185 1.3E-26 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS09625 7df191b9d93052038cfd5fe7ea57082c 396 SUPERFAMILY SSF46689 207 267 8.21E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 Gene3D G3DSA:1.10.1040.10 201 375 2.4E-41 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 375 35.552 T 09-03-2017 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 SUPERFAMILY SSF51735 2 200 5.4E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 151 362 5.3E-47 T 09-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 122 1.3E-19 T 09-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 3.0E-14 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 PRINTS PR00084 Mannitol dehydrogenase signature 149 162 3.0E-14 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 3.0E-14 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 PRINTS PR00084 Mannitol dehydrogenase signature 167 182 3.0E-14 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 SUPERFAMILY SSF48179 202 374 3.09E-42 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS20215 e2221971c5cf7c36027645eb1c209342 381 Gene3D G3DSA:3.40.50.720 2 198 7.6E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 Pfam PF00413 Matrixin 253 280 2.4E-6 T 09-03-2017 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 PRINTS PR00138 Matrixin signature 148 163 9.8E-5 T 09-03-2017 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 PRINTS PR00138 Matrixin signature 255 280 9.8E-5 T 09-03-2017 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 SUPERFAMILY SSF55486 127 286 1.0E-13 T 09-03-2017 ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 SMART SM00235 120 299 0.0093 T 09-03-2017 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 ARZXY2_RS14015 e93872962839ac95871995fd4d8540b7 306 Gene3D G3DSA:3.40.390.10 129 296 4.4E-10 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ARZXY2_RS07175 471fbfa978acf8a8a8069d3f304ff8df 246 Gene3D G3DSA:3.40.50.880 3 238 3.1E-38 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07175 471fbfa978acf8a8a8069d3f304ff8df 246 Pfam PF07722 Peptidase C26 4 211 2.3E-52 T 09-03-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 ARZXY2_RS07175 471fbfa978acf8a8a8069d3f304ff8df 246 SUPERFAMILY SSF52317 30 235 3.25E-35 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS02265 ffe41ee0b73155385305e86970435351 152 SUPERFAMILY SSF55961 1 150 1.26E-21 T 09-03-2017 ARZXY2_RS02265 ffe41ee0b73155385305e86970435351 152 Gene3D G3DSA:3.30.530.20 8 150 1.3E-18 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS02265 ffe41ee0b73155385305e86970435351 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 150 1.2E-18 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 Gene3D G3DSA:3.30.572.10 7 267 3.9E-128 T 09-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 PRINTS PR00108 Thymidylate synthase family signature 162 188 3.5E-47 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 PRINTS PR00108 Thymidylate synthase family signature 200 217 3.5E-47 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 PRINTS PR00108 Thymidylate synthase family signature 144 159 3.5E-47 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 PRINTS PR00108 Thymidylate synthase family signature 45 66 3.5E-47 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 PRINTS PR00108 Thymidylate synthase family signature 118 137 3.5E-47 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 Hamap MF_00008 Thymidylate synthase [thyA]. 4 267 39.478 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 Pfam PF00303 Thymidylate synthase 6 267 3.3E-120 T 09-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 87 4.4E-37 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 267 2.9E-87 T 09-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 SUPERFAMILY SSF55831 6 267 7.85E-125 T 09-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS03285 d3b522c729f8e855994ad56330abd372 267 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 09-03-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 ARZXY2_RS10665 91869beecb42ff639b44ca0e6d2ade9c 312 Pfam PF09754 PAC2 family 37 253 3.6E-41 T 09-03-2017 IPR019151 Proteasome assembly chaperone 2 ARZXY2_RS10665 91869beecb42ff639b44ca0e6d2ade9c 312 Gene3D G3DSA:1.10.287.100 235 276 5.4E-15 T 09-03-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 ARZXY2_RS10665 91869beecb42ff639b44ca0e6d2ade9c 312 PIRSF PIRSF028754 17 312 6.6E-89 T 09-03-2017 IPR008492 Protein of unknown function DUF774 ARZXY2_RS10665 91869beecb42ff639b44ca0e6d2ade9c 312 SUPERFAMILY SSF159659 20 274 1.44E-83 T 09-03-2017 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 PRINTS PR00171 Sugar transporter signature 39 49 4.0E-22 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 PRINTS PR00171 Sugar transporter signature 282 292 4.0E-22 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 PRINTS PR00171 Sugar transporter signature 395 407 4.0E-22 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 PRINTS PR00171 Sugar transporter signature 122 141 4.0E-22 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 Pfam PF00083 Sugar (and other) transporter 31 470 4.6E-106 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 6 466 3.4E-102 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 SUPERFAMILY SSF103473 13 469 1.14E-77 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 102 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 Gene3D G3DSA:1.20.1250.20 273 468 5.0E-23 T 09-03-2017 ARZXY2_RS12615 34819d2501052c3d2372a1f7361b4ded 482 Gene3D G3DSA:1.20.1250.20 33 216 1.1E-27 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 463 6.0E-176 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 3.4E-51 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Gene3D G3DSA:1.10.40.30 382 439 1.8E-29 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Pfam PF00206 Lyase 19 308 1.9E-58 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 2.5E-23 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 2.5E-23 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 2.5E-23 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 2.5E-23 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 SUPERFAMILY SSF48557 13 464 1.19E-132 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Pfam PF14698 Argininosuccinate lyase C-terminal 371 438 4.7E-22 T 09-03-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Gene3D G3DSA:1.20.200.10 115 381 4.0E-95 T 09-03-2017 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 461 39.475 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11195 6fd6dec471462d566466dedb004483be 471 Gene3D G3DSA:1.10.275.10 9 114 8.6E-32 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS16540 85e9c92cc8f00be1a1e135a34f399211 191 SUPERFAMILY SSF143744 51 186 4.32E-28 T 09-03-2017 ARZXY2_RS16540 85e9c92cc8f00be1a1e135a34f399211 191 Pfam PF03928 Haem-degrading 66 183 5.5E-23 T 09-03-2017 IPR005624 Haem-degrading ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Gene3D G3DSA:3.30.9.10 207 260 2.5E-4 T 09-03-2017 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Gene3D G3DSA:3.30.9.10 110 128 2.5E-4 T 09-03-2017 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Gene3D G3DSA:3.50.50.60 4 81 2.3E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Gene3D G3DSA:3.50.50.60 299 346 2.3E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Gene3D G3DSA:3.50.50.60 129 206 2.3E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 Pfam PF01266 FAD dependent oxidoreductase 6 337 1.6E-43 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 SUPERFAMILY SSF51905 5 207 1.04E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12290 9c240ad33a744dd85b66550e5b5d617c 361 SUPERFAMILY SSF51905 299 349 1.04E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13270 ca5682eb2d200e4a0bed978a42cbda74 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 49 70 4.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13270 ca5682eb2d200e4a0bed978a42cbda74 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 224 243 4.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13270 ca5682eb2d200e4a0bed978a42cbda74 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 4.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13270 ca5682eb2d200e4a0bed978a42cbda74 284 PIRSF PIRSF006648 4 283 3.4E-21 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13270 ca5682eb2d200e4a0bed978a42cbda74 284 Pfam PF01061 ABC-2 type transporter 50 243 4.3E-18 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 234 2.8E-70 T 09-03-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 09-03-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 SMART SM00882 6 235 3.7E-91 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 Gene3D G3DSA:3.40.1080.10 4 234 9.2E-105 T 09-03-2017 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 Pfam PF01144 Coenzyme A transferase 7 234 6.3E-76 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS11690 e499be3e56bd61542259127806a2a55d 265 SUPERFAMILY SSF100950 2 246 1.88E-90 T 09-03-2017 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 Gene3D G3DSA:3.30.465.10 107 227 2.2E-42 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 Gene3D G3DSA:1.10.45.10 427 466 1.6E-8 T 09-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 SUPERFAMILY SSF56176 14 227 2.2E-67 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 227 465 6.0E-44 T 09-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 Pfam PF01565 FAD binding domain 51 190 9.0E-43 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 SUPERFAMILY SSF55103 200 466 1.13E-43 T 09-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 ARZXY2_RS14800 aface0a21cb302daef139a3942ebe721 467 Gene3D G3DSA:3.30.43.10 8 106 9.6E-26 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 SUPERFAMILY SSF56059 24 256 8.83E-94 T 09-03-2017 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 SUPERFAMILY SSF56059 297 378 8.83E-94 T 09-03-2017 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 Pfam PF00391 PEP-utilising enzyme, mobile domain 873 944 2.8E-25 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 39 353 1.2E-95 T 09-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 Gene3D G3DSA:3.30.470.20 204 361 2.4E-42 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 SUPERFAMILY SSF52009 847 947 1.83E-27 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 Gene3D G3DSA:3.50.30.10 872 947 5.3E-27 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 ARZXY2_RS16730 105f19132c091f290dc57cb86259acfc 949 Gene3D G3DSA:3.30.1490.20 25 203 2.7E-60 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 Pfam PF00171 Aldehyde dehydrogenase family 14 475 6.2E-147 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 Gene3D G3DSA:3.40.309.10 261 450 5.6E-60 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 SUPERFAMILY SSF53720 6 478 4.71E-150 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10095 f11f3dfe9884f3e676811b98a7f8c707 479 Gene3D G3DSA:3.40.605.10 7 260 2.8E-90 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 SUPERFAMILY SSF55424 350 464 1.37E-27 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 Gene3D G3DSA:3.50.50.60 11 147 1.0E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 347 368 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 454 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 282 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 427 2.9E-49 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 SUPERFAMILY SSF51905 9 340 5.19E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PIRSF PIRSF000350 2 463 3.4E-76 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 459 3.0E-24 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 331 2.0E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 Gene3D G3DSA:3.30.390.30 347 463 3.2E-30 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.5E-32 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 1.5E-32 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.5E-32 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.5E-32 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 1.5E-32 T 09-03-2017 ARZXY2_RS12550 317d73af99af6294723e88851675fd9f 467 Gene3D G3DSA:3.50.50.60 148 340 3.4E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15210 9e26b6028f1be42af984723ec38f9aa4 289 Pfam PF00486 Transcriptional regulatory protein, C terminal 199 273 5.6E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS15210 9e26b6028f1be42af984723ec38f9aa4 289 Gene3D G3DSA:1.10.10.10 180 274 2.2E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15210 9e26b6028f1be42af984723ec38f9aa4 289 SUPERFAMILY SSF46894 180 274 2.35E-24 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS15210 9e26b6028f1be42af984723ec38f9aa4 289 SMART SM00862 199 273 4.2E-22 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 SUPERFAMILY SSF50129 11 184 1.89E-40 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 Gene3D G3DSA:3.40.50.720 179 294 6.4E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 144 2.9E-14 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 SUPERFAMILY SSF51735 150 311 1.55E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 Gene3D G3DSA:3.90.180.10 8 178 1.4E-36 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS07410 6cae8a9690c00768a5f0bd010d815041 349 Pfam PF00107 Zinc-binding dehydrogenase 187 308 2.4E-17 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS16755 22eba6bc622479f269006f1650a9b9e4 480 Pfam PF00860 Permease family 25 430 4.8E-30 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 7 166 7.6E-45 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 SUPERFAMILY SSF55811 5 171 6.91E-46 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 5 178 32.288 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 Pfam PF00293 NUDIX domain 32 163 9.2E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 PIRSF PIRSF018427 1 179 1.9E-51 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 ARZXY2_RS17120 222cede2f63e258d5b1040c329fd8fea 182 Gene3D G3DSA:3.90.79.10 32 175 2.6E-41 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 326 55.812 T 09-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 Gene3D G3DSA:3.40.50.720 3 188 6.4E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 SUPERFAMILY SSF51735 3 323 1.11E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 Gene3D G3DSA:3.90.25.10 190 326 2.3E-46 T 09-03-2017 ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 316 9.0E-138 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02490 5b53e3ea41e51dd80d5f6d53399a8213 342 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 4 323 3.2E-156 T 09-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 Gene3D G3DSA:1.10.260.40 5 55 1.1E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 Pfam PF13377 Periplasmic binding protein-like domain 174 348 7.5E-31 T 09-03-2017 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 SUPERFAMILY SSF53822 67 349 1.65E-51 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 51 6.7E-11 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 SUPERFAMILY SSF47413 5 64 1.69E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 Gene3D G3DSA:3.40.50.2300 177 324 3.8E-41 T 09-03-2017 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 Gene3D G3DSA:3.40.50.2300 56 176 3.2E-24 T 09-03-2017 ARZXY2_RS17180 75308acf44ee6c8e390a9333d1fce14c 352 SMART SM00354 6 76 1.6E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13550 c852b994ad65df3ef800c8cfab3e98b2 204 Pfam PF01872 RibD C-terminal domain 4 172 8.1E-14 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS13550 c852b994ad65df3ef800c8cfab3e98b2 204 Gene3D G3DSA:3.40.430.10 6 189 1.1E-19 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS13550 c852b994ad65df3ef800c8cfab3e98b2 204 SUPERFAMILY SSF53597 9 189 3.14E-20 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 Gene3D G3DSA:3.40.50.620 20 321 1.8E-91 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 SMART SM00840 368 430 3.9E-15 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 485 2.3E-127 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 487 35.485 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 329 5.9E-109 T 09-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 Pfam PF09190 DALR domain 368 429 2.2E-12 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 SUPERFAMILY SSF52374 4 328 1.56E-81 T 09-03-2017 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 Gene3D G3DSA:1.20.120.640 325 420 1.9E-18 T 09-03-2017 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 SUPERFAMILY SSF47323 357 486 6.67E-33 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.2E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.2E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 240 261 2.2E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS14880 c13aedef69bec5541347fc468a2dfed3 489 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 209 227 2.2E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS04845 671fe472392718e854396480ae11e78d 363 PIRSF PIRSF000390 1 363 3.4E-108 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase ARZXY2_RS04845 671fe472392718e854396480ae11e78d 363 Gene3D G3DSA:3.40.640.10 5 242 1.6E-83 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS04845 671fe472392718e854396480ae11e78d 363 SUPERFAMILY SSF53383 5 359 2.28E-108 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS04845 671fe472392718e854396480ae11e78d 363 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 355 3.7E-121 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase ARZXY2_RS04845 671fe472392718e854396480ae11e78d 363 Gene3D G3DSA:3.90.1150.10 245 360 4.3E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS06930 b4f7458acf6b5d0e078634ec60bc9f85 400 Gene3D G3DSA:1.20.1250.20 233 392 5.2E-14 T 09-03-2017 ARZXY2_RS06930 b4f7458acf6b5d0e078634ec60bc9f85 400 Gene3D G3DSA:1.20.1250.20 7 196 8.0E-20 T 09-03-2017 ARZXY2_RS06930 b4f7458acf6b5d0e078634ec60bc9f85 400 Pfam PF07690 Major Facilitator Superfamily 14 252 1.1E-12 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS06930 b4f7458acf6b5d0e078634ec60bc9f85 400 SUPERFAMILY SSF103473 8 394 1.24E-42 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 Gene3D G3DSA:3.30.830.10 37 231 5.3E-51 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 SUPERFAMILY SSF63411 258 443 1.34E-47 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 58 81 - T 09-03-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 Pfam PF00675 Insulinase (Peptidase family M16) 37 184 1.5E-34 T 09-03-2017 IPR011765 Peptidase M16, N-terminal ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 Gene3D G3DSA:3.30.830.10 262 441 4.7E-53 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 SUPERFAMILY SSF63411 28 230 3.32E-54 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 ARZXY2_RS11500 921ebff5ed8490f2970784ab6cbac053 447 Pfam PF05193 Peptidase M16 inactive domain 192 373 1.9E-33 T 09-03-2017 IPR007863 Peptidase M16, C-terminal ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SUPERFAMILY SSF55021 711 790 2.29E-13 T 09-03-2017 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Pfam PF02824 TGS domain 457 516 2.3E-22 T 09-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Gene3D G3DSA:3.30.460.10 243 389 1.0E-49 T 09-03-2017 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Pfam PF13291 ACT domain 712 788 2.7E-15 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SMART SM00954 300 410 6.6E-67 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 93 788 5.0E-248 T 09-03-2017 IPR004811 RelA/SpoT family GO:0015969 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SUPERFAMILY SSF81301 245 461 3.43E-65 T 09-03-2017 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SUPERFAMILY SSF109604 70 255 1.29E-70 T 09-03-2017 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SMART SM00471 108 218 3.5E-11 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 SUPERFAMILY SSF81271 445 516 4.8E-21 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Pfam PF04607 Region found in RelA / SpoT proteins 300 409 1.7E-37 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Gene3D G3DSA:3.10.20.30 456 518 2.5E-23 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Gene3D G3DSA:3.30.70.260 714 786 2.4E-12 T 09-03-2017 ARZXY2_RS08000 52f30256ab3276a9da1e50452ce03d43 796 Pfam PF13328 HD domain 93 240 2.0E-47 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 196 217 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 42 60 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 249 267 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 73 86 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 86 103 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00690 Adhesin family signature 275 294 1.9E-40 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 Gene3D G3DSA:3.40.50.1980 188 310 1.0E-39 T 09-03-2017 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 86 105 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 42 63 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 67 85 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 222 240 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 196 213 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 PRINTS PR00691 Adhesin B signature 245 262 2.0E-33 T 09-03-2017 IPR006129 Adhesin B GO:0007155 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 Pfam PF01297 Zinc-uptake complex component A periplasmic 45 308 3.1E-70 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 Gene3D G3DSA:3.40.50.1980 30 187 2.0E-47 T 09-03-2017 ARZXY2_RS02235 0903c6c2df8786f1eb367744d6ba6b06 314 SUPERFAMILY SSF53807 38 310 4.41E-84 T 09-03-2017 ARZXY2_RS10765 5522dc76a8aa91e703de871e347bb826 267 Pfam PF00480 ROK family 15 175 1.3E-27 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS10765 5522dc76a8aa91e703de871e347bb826 267 SUPERFAMILY SSF53067 14 262 7.25E-42 T 09-03-2017 ARZXY2_RS10765 5522dc76a8aa91e703de871e347bb826 267 Gene3D G3DSA:3.30.420.40 123 258 3.2E-38 T 09-03-2017 ARZXY2_RS10765 5522dc76a8aa91e703de871e347bb826 267 Gene3D G3DSA:3.30.420.40 9 122 1.2E-47 T 09-03-2017 ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 Gene3D G3DSA:3.20.20.120 122 374 5.6E-67 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4 126 1.2E-21 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 SMART SM00922 144 243 1.1E-16 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 Pfam PF13378 Enolase C-terminal domain-like 151 363 1.5E-52 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 101 126 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 SUPERFAMILY SSF54826 1 126 2.4E-34 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 Gene3D G3DSA:3.30.390.10 1 121 1.6E-42 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 SUPERFAMILY SSF51604 114 372 1.02E-63 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS19250 0674019c0bfe47a8efc4b1f1e67d4dc6 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 189 220 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 4.6E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 4.6E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 4.6E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 4.6E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SUPERFAMILY SSF55874 299 472 1.7E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SMART SM00387 357 473 1.0E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 Gene3D G3DSA:1.10.287.130 238 296 3.6E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 309 7.3E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SUPERFAMILY SSF158472 185 231 4.71E-7 T 09-03-2017 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SUPERFAMILY SSF47384 233 310 1.45E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 Gene3D G3DSA:3.30.565.10 297 475 5.3E-49 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SMART SM00388 243 310 4.7E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 SMART SM00304 182 235 6.0E-11 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 Pfam PF00672 HAMP domain 163 231 3.2E-12 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS14305 f17c53ea0fc8fcc6c5339dbf5c505459 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 472 2.6E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11980 32b593a1d6b48efb395d42cb70d0d73a 276 Gene3D G3DSA:2.60.40.10 197 272 2.1E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS11980 32b593a1d6b48efb395d42cb70d0d73a 276 SUPERFAMILY SSF81296 204 269 3.92E-11 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS11980 32b593a1d6b48efb395d42cb70d0d73a 276 Pfam PF01833 IPT/TIG domain 206 264 1.9E-8 T 09-03-2017 IPR002909 IPT domain GO:0005515 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 45 475 3.5E-145 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 SUPERFAMILY SSF101904 529 791 6.28E-43 T 09-03-2017 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Gene3D G3DSA:2.120.10.90 529 785 3.6E-38 T 09-03-2017 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 SMART SM00434 24 477 4.9E-247 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Gene3D G3DSA:3.30.1360.40 248 345 1.0E-28 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 SUPERFAMILY SSF56719 44 499 1.57E-162 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Gene3D G3DSA:3.90.199.10 44 247 3.3E-107 T 09-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Gene3D G3DSA:3.90.199.10 346 411 3.3E-107 T 09-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 680 723 2.4E-9 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ARZXY2_RS10595 a1a072d083ce69a0f7ae082cc5eb70df 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 750 778 0.06 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 PIRSF PIRSF000103 4 310 4.9E-80 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 Gene3D G3DSA:1.10.1040.10 174 304 3.8E-41 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 14 27 - T 09-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 Gene3D G3DSA:3.40.50.720 12 173 1.6E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 14 301 4.8E-114 T 09-03-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 175 299 6.2E-36 T 09-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 SUPERFAMILY SSF48179 173 303 1.7E-36 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 SUPERFAMILY SSF51735 12 173 1.06E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16345 9166a042775047df7a9c9612f8ba5519 320 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 172 9.5E-46 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 SUPERFAMILY SSF88946 63 153 1.04E-24 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 SUPERFAMILY SSF88659 178 235 4.49E-14 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 Gene3D G3DSA:1.10.1740.10 61 141 1.4E-27 T 09-03-2017 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 Gene3D G3DSA:1.10.10.10 174 238 5.4E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 Pfam PF04542 Sigma-70 region 2 75 139 5.1E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 59 248 3.6E-115 T 09-03-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 72 235 2.4E-25 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS05030 fd683a193563053bd7da8687fb591c07 263 Pfam PF08281 Sigma-70, region 4 181 231 9.1E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 28 152 1.0E-50 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 SUPERFAMILY SSF52304 14 153 2.75E-58 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 Gene3D G3DSA:3.40.50.9100 14 153 3.1E-63 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 Pfam PF01220 Dehydroquinase class II 15 150 4.8E-59 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 ProSitePatterns PS01029 Dehydroquinase class II signature. 18 35 - T 09-03-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 PIRSF PIRSF001399 12 154 5.1E-59 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 15 153 6.8E-59 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS01740 c9ffef77a1142b053ef04dfdf777a424 154 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 154 67.786 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 Pfam PF13344 Haloacid dehalogenase-like hydrolase 39 142 2.3E-24 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 SUPERFAMILY SSF56784 36 288 9.74E-69 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 Pfam PF13242 HAD-hyrolase-like 215 288 3.2E-22 T 09-03-2017 ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 40 264 1.1E-47 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 Gene3D G3DSA:3.40.50.1000 215 290 2.6E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 Gene3D G3DSA:3.40.50.1000 34 112 2.6E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS16170 3fd230f7ecda59c1131b7f3905b4eb02 292 Gene3D G3DSA:3.40.50.10410 122 214 1.2E-33 T 09-03-2017 IPR023215 Nitrophenylphosphatase-like domain ARZXY2_RS17195 fce372f6b147af2b41718c874992f3e4 133 SUPERFAMILY SSF54593 5 133 3.62E-27 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS17195 fce372f6b147af2b41718c874992f3e4 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 130 3.6E-17 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS17195 fce372f6b147af2b41718c874992f3e4 133 Gene3D G3DSA:3.10.180.10 1 132 1.4E-31 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 Gene3D G3DSA:3.40.50.300 286 492 1.1E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 Gene3D G3DSA:3.40.50.300 19 250 2.4E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 Pfam PF00005 ABC transporter 37 186 3.6E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 Pfam PF00005 ABC transporter 285 438 7.0E-16 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 SUPERFAMILY SSF52540 285 491 1.17E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 SMART SM00382 46 234 6.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 SMART SM00382 293 487 0.0036 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00750 9dc5ee8774631e3fe6f3c538abc73856 509 SUPERFAMILY SSF52540 19 246 5.06E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02190 e81b89a826cadcfc0a9cd66734fa3930 501 Gene3D G3DSA:3.40.50.300 35 83 8.7E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02190 e81b89a826cadcfc0a9cd66734fa3930 501 Gene3D G3DSA:3.40.50.300 134 216 8.7E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02190 e81b89a826cadcfc0a9cd66734fa3930 501 SUPERFAMILY SSF52540 35 215 2.61E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02190 e81b89a826cadcfc0a9cd66734fa3930 501 Pfam PF00350 Dynamin family 43 186 9.7E-12 T 09-03-2017 IPR022812 Dynamin superfamily ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 PRINTS PR01438 Universal stress protein signature 102 114 2.9E-16 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 PRINTS PR01438 Universal stress protein signature 7 25 2.9E-16 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 PRINTS PR01438 Universal stress protein signature 120 142 2.9E-16 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 Pfam PF00582 Universal stress protein family 10 142 5.1E-23 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 Gene3D G3DSA:3.40.50.620 8 142 1.0E-32 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS09880 ac5a2df5dcdeba2e730b9e966cb08109 149 SUPERFAMILY SSF52402 10 144 2.09E-31 T 09-03-2017 ARZXY2_RS06505 a757094c7744265f9bcddd9d8440a19d 229 PIRSF PIRSF011491 1 221 1.4E-87 T 09-03-2017 IPR016584 S-adenosyl-L-methionine dependent methyltransferase, YbcY, predicted ARZXY2_RS06505 a757094c7744265f9bcddd9d8440a19d 229 Pfam PF13489 Methyltransferase domain 51 208 7.4E-10 T 09-03-2017 ARZXY2_RS06505 a757094c7744265f9bcddd9d8440a19d 229 Gene3D G3DSA:3.40.50.150 39 213 9.6E-15 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS06505 a757094c7744265f9bcddd9d8440a19d 229 SUPERFAMILY SSF53335 40 213 8.12E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 PIRSF PIRSF002741 1 535 7.6E-82 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 457 5.7E-72 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 Gene3D G3DSA:3.90.76.10 60 169 2.1E-19 T 09-03-2017 ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 SUPERFAMILY SSF53850 29 533 2.72E-107 T 09-03-2017 ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 Gene3D G3DSA:3.10.105.10 307 504 6.0E-42 T 09-03-2017 ARZXY2_RS05580 f97f113bc088c11c748f60f55274c2e0 536 Gene3D G3DSA:3.40.190.10 170 306 3.8E-34 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 SUPERFAMILY SSF52540 72 293 8.9E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 174 198 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 248 274 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 124 141 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 213 241 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 16 40 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 322 345 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 PRINTS PR01874 DNA repair protein radA signature 82 110 2.1E-82 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 Gene3D G3DSA:3.40.50.300 68 275 1.1E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 SUPERFAMILY SSF54211 294 455 2.01E-34 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 Hamap MF_01498 DNA repair protein RadA [radA]. 27 456 40.871 T 09-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 SMART SM00382 90 244 1.9E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 452 3.5E-152 T 09-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 Pfam PF13481 AAA domain 65 222 2.0E-16 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 368 428 8.6E-9 T 09-03-2017 ARZXY2_RS17725 707012387d2d675710df6dde8d50bae6 457 Gene3D G3DSA:3.30.230.10 284 455 2.3E-31 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Pfam PF00501 AMP-binding enzyme 52 449 3.3E-71 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Gene3D G3DSA:3.30.300.30 444 542 3.7E-22 T 09-03-2017 ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 535 4.5E-20 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Gene3D G3DSA:3.40.50.980 209 367 3.8E-25 T 09-03-2017 ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 SUPERFAMILY SSF56801 20 545 9.16E-130 T 09-03-2017 ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Gene3D G3DSA:2.30.38.10 368 442 3.5E-19 T 09-03-2017 ARZXY2_RS16315 d5a381f12c1e9ce8e34e65f9a04e164c 572 Gene3D G3DSA:3.40.50.980 52 208 5.2E-27 T 09-03-2017 ARZXY2_RS09150 7c4aade072cba4b7e29a6248d2ef5435 441 Gene3D G3DSA:1.20.1250.20 16 203 8.6E-14 T 09-03-2017 ARZXY2_RS09150 7c4aade072cba4b7e29a6248d2ef5435 441 Gene3D G3DSA:1.20.1250.20 238 432 3.1E-21 T 09-03-2017 ARZXY2_RS09150 7c4aade072cba4b7e29a6248d2ef5435 441 Pfam PF07690 Major Facilitator Superfamily 25 269 1.6E-16 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09150 7c4aade072cba4b7e29a6248d2ef5435 441 Pfam PF07690 Major Facilitator Superfamily 292 431 2.3E-12 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09150 7c4aade072cba4b7e29a6248d2ef5435 441 SUPERFAMILY SSF103473 13 437 1.09E-44 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 13 198 1.2E-39 T 09-03-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 Pfam PF01171 PP-loop family 14 193 3.8E-36 T 09-03-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 Gene3D G3DSA:3.40.50.620 12 174 6.8E-11 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 306 20.674 T 09-03-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 Pfam PF09179 TilS substrate binding domain 250 307 4.4E-4 T 09-03-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 SUPERFAMILY SSF82829 206 307 1.39E-15 T 09-03-2017 ARZXY2_RS18010 91eb168aee21a2f7b6b8aec521024430 352 SUPERFAMILY SSF52402 12 229 1.09E-47 T 09-03-2017 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Gene3D G3DSA:3.40.50.300 4 236 1.2E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Pfam PF03459 TOBE domain 293 349 5.7E-7 T 09-03-2017 IPR005116 Transport-associated OB, type 1 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 SUPERFAMILY SSF50331 238 358 5.35E-27 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 SUPERFAMILY SSF52540 4 245 8.28E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Pfam PF00005 ABC transporter 22 163 1.9E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Gene3D G3DSA:2.40.50.100 344 358 4.0E-8 T 09-03-2017 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Gene3D G3DSA:2.40.50.100 241 281 4.0E-8 T 09-03-2017 ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 SMART SM00382 30 213 2.8E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14770 a874ac119e062859cc5f32d28be44a4d 360 Gene3D G3DSA:2.40.50.140 282 342 6.9E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS01225 9909b2d418e71bc84fad96a95811c79c 389 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 377 5.4E-116 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS01225 9909b2d418e71bc84fad96a95811c79c 389 PIRSF PIRSF006078 1 382 7.9E-117 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS01225 9909b2d418e71bc84fad96a95811c79c 389 Gene3D G3DSA:3.90.1510.10 44 279 1.0E-83 T 09-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 ARZXY2_RS01225 9909b2d418e71bc84fad96a95811c79c 389 Pfam PF02595 Glycerate kinase family 3 374 2.7E-125 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS01225 9909b2d418e71bc84fad96a95811c79c 389 SUPERFAMILY SSF110738 1 373 1.83E-111 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS19955 ea2dfe53a4a5d72563f3169f7bae69b1 337 Gene3D G3DSA:2.40.100.10 198 300 2.9E-5 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS19955 ea2dfe53a4a5d72563f3169f7bae69b1 337 SMART SM00797 25 306 1.9E-61 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS19955 ea2dfe53a4a5d72563f3169f7bae69b1 337 Pfam PF02626 Allophanate hydrolase subunit 2 26 288 1.2E-63 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS19955 ea2dfe53a4a5d72563f3169f7bae69b1 337 SUPERFAMILY SSF50891 198 295 1.06E-5 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 116 19.351 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 09-03-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 SUPERFAMILY SSF89919 1 112 1.31E-29 T 09-03-2017 IPR023799 Ribosome-binding factor A domain ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 8.1E-27 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 Pfam PF02033 Ribosome-binding factor A 6 109 1.1E-25 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 Gene3D G3DSA:3.30.300.20 3 117 8.3E-38 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS11545 a254fc840d83c1237c2ca04d79c8dc65 167 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 10 96 4.0E-40 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 406 1.5E-5 T 09-03-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 SMART SM00849 32 226 1.5E-21 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 Pfam PF00753 Metallo-beta-lactamase superfamily 30 175 1.6E-11 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 563 40.18 T 09-03-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 SUPERFAMILY SSF56281 20 434 1.83E-89 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 Gene3D G3DSA:3.60.15.10 19 266 1.2E-73 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 PIRSF PIRSF004803 13 563 1.0E-212 T 09-03-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 ARZXY2_RS11420 985fe43b2d104eedbd65afc131b63b02 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 560 1.9E-150 T 09-03-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 154 3.5E-53 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 56 5.8E-17 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 9.0E-37 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 9.0E-37 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 9.0E-37 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 9.0E-37 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 9.0E-37 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 Gene3D G3DSA:3.40.50.620 1 154 1.7E-49 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 30.979 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 Pfam PF01467 Cytidylyltransferase-like 6 133 6.6E-19 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS05815 ff1cc3c86bb072d5d5dd9f730f3625e1 166 SUPERFAMILY SSF52374 1 154 8.58E-44 T 09-03-2017 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 328 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 Gene3D G3DSA:1.20.1250.20 21 234 2.9E-19 T 09-03-2017 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 Gene3D G3DSA:1.20.1250.20 252 441 9.1E-24 T 09-03-2017 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 Pfam PF07690 Major Facilitator Superfamily 64 283 3.7E-17 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 Pfam PF07690 Major Facilitator Superfamily 284 441 3.9E-11 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS19960 ea91cfd51cf00fc541cc33ed79d88acc 446 SUPERFAMILY SSF103473 19 443 6.93E-63 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 Gene3D G3DSA:2.130.10.10 27 147 2.1E-12 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 SUPERFAMILY SSF50969 81 351 7.85E-20 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 Gene3D G3DSA:2.130.10.10 148 352 1.6E-22 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 510 570 1.1E-6 T 09-03-2017 ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 360 420 5.6E-7 T 09-03-2017 ARZXY2_RS13460 df06cb8ae4c4e4d1dbc49b3790e204df 606 SUPERFAMILY SSF69318 328 602 1.12E-27 T 09-03-2017 ARZXY2_RS16745 794f325156da91fd49bc2b8495922c0f 261 SUPERFAMILY SSF54001 152 249 1.08E-14 T 09-03-2017 ARZXY2_RS16745 794f325156da91fd49bc2b8495922c0f 261 Gene3D G3DSA:3.90.1720.10 174 246 1.2E-10 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS16745 794f325156da91fd49bc2b8495922c0f 261 Pfam PF00877 NlpC/P60 family 173 233 9.0E-6 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 Pfam PF00072 Response regulator receiver domain 6 126 3.5E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 SUPERFAMILY SSF52172 1 135 9.96E-30 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 4.5E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 SMART SM00448 4 126 2.5E-33 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 SUPERFAMILY SSF46894 143 215 1.33E-19 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 SMART SM00421 152 209 2.6E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 Gene3D G3DSA:1.10.10.10 132 215 6.8E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18680 2a0147458615fe8e178277628335943c 218 Gene3D G3DSA:3.40.50.2300 1 131 2.0E-34 T 09-03-2017 ARZXY2_RS04625 cae42c00d5697b396645410d23ee300c 177 SUPERFAMILY SSF52540 7 166 1.02E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04625 cae42c00d5697b396645410d23ee300c 177 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 10 155 1.5E-56 T 09-03-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 ARZXY2_RS04625 cae42c00d5697b396645410d23ee300c 177 Gene3D G3DSA:3.40.50.300 3 167 5.5E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04625 cae42c00d5697b396645410d23ee300c 177 Pfam PF01202 Shikimate kinase 16 165 4.2E-10 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 4.8E-56 T 09-03-2017 ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 SUPERFAMILY SSF51735 14 253 2.23E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS09725 95f0a3ae52694f1a6b650d3d06a31886 255 Gene3D G3DSA:3.40.50.720 10 253 7.1E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 199 490 18.666 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 SUPERFAMILY SSF64153 1 220 4.32E-45 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 Gene3D G3DSA:3.40.50.10260 1 205 1.6E-54 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 Gene3D G3DSA:3.40.1190.20 206 487 1.5E-75 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 1 187 2.0E-32 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 406 416 - T 09-03-2017 IPR017953 Carbohydrate kinase, predicted, conserved site ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 Pfam PF01256 Carbohydrate kinase 223 465 7.8E-42 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 197 430 1.6E-38 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 SUPERFAMILY SSF53613 197 485 1.48E-50 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 Pfam PF03853 YjeF-related protein N-terminus 1 166 1.5E-36 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 ARZXY2_RS03765 22bc094c9eebf3741281a4cbf7df651f 497 PIRSF PIRSF017184 1 491 5.9E-93 T 09-03-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 SUPERFAMILY SSF52833 4 103 9.09E-31 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 Pfam PF00085 Thioredoxin 5 101 2.7E-25 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 Gene3D G3DSA:3.40.30.10 4 102 2.6E-32 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 PIRSF PIRSF000077 1 104 5.4E-27 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 PRINTS PR00421 Thioredoxin family signature 68 79 6.3E-8 T 09-03-2017 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 PRINTS PR00421 Thioredoxin family signature 29 38 6.3E-8 T 09-03-2017 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 PRINTS PR00421 Thioredoxin family signature 21 29 6.3E-8 T 09-03-2017 ARZXY2_RS00140 10fb1af73f04194f89bc3d325b331bea 120 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.2E-28 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.9E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 2.0E-67 T 09-03-2017 ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 SUPERFAMILY SSF51735 6 256 1.38E-81 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07170 61b2c9bf784a1d324d61049b0c400683 257 Gene3D G3DSA:3.40.50.720 5 256 9.9E-85 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 SUPERFAMILY SSF46785 13 75 3.72E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 Gene3D G3DSA:3.30.450.40 88 257 1.5E-41 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 Pfam PF01614 Bacterial transcriptional regulator 130 253 2.3E-19 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 Gene3D G3DSA:1.10.10.10 11 74 4.6E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 SMART SM00346 13 101 0.0033 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 SUPERFAMILY SSF55781 88 254 3.99E-35 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17030 95465d8acc9887764525d02e477e77bf 264 Pfam PF09339 IclR helix-turn-helix domain 15 64 2.5E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 Gene3D G3DSA:3.90.180.10 1 146 3.2E-49 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 SUPERFAMILY SSF50129 1 141 1.98E-39 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 2.5E-141 T 09-03-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 Gene3D G3DSA:3.40.50.720 147 262 9.6E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 SUPERFAMILY SSF51735 112 289 1.72E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 SMART SM00829 10 325 3.3E-52 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 3.9E-7 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS15040 6cb3fb9a2f389eaf348ac535f2ea5d45 327 Pfam PF00107 Zinc-binding dehydrogenase 152 266 5.0E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 144 161 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 Gene3D G3DSA:3.20.20.100 6 290 3.6E-99 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 Pfam PF00248 Aldo/keto reductase family 24 279 2.7E-45 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 PIRSF PIRSF000097 4 293 8.1E-76 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 SUPERFAMILY SSF51430 5 285 9.95E-87 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 PRINTS PR00069 Aldo-keto reductase signature 144 161 1.7E-36 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.7E-36 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 PRINTS PR00069 Aldo-keto reductase signature 215 239 1.7E-36 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS08195 13cda84e77b97065256ffcbe04a89413 293 PRINTS PR00069 Aldo-keto reductase signature 178 207 1.7E-36 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 SUPERFAMILY SSF48163 336 504 3.01E-34 T 09-03-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 23 339 1.4E-78 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Gene3D G3DSA:3.90.800.10 88 210 2.5E-32 T 09-03-2017 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 38 2.1E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 2.1E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 40 51 2.1E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 55 68 2.1E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 PRINTS PR00987 Glutamyl-tRNA synthetase signature 226 234 2.1E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Gene3D G3DSA:1.10.10.350 410 503 3.4E-19 T 09-03-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 23 502 2.7E-125 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 23 505 30.6 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 SUPERFAMILY SSF52374 23 335 1.1E-96 T 09-03-2017 ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Gene3D G3DSA:3.40.50.620 23 87 6.7E-44 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Gene3D G3DSA:3.40.50.620 212 266 6.7E-44 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS05700 a93877b17daf6e8b02c57e851807d34b 506 Gene3D G3DSA:1.10.1160.10 269 351 6.7E-26 T 09-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 Gene3D G3DSA:3.10.20.70 4 107 1.9E-34 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 SUPERFAMILY SSF54368 4 102 1.05E-30 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 09-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 SUPERFAMILY SSF55931 105 473 8.24E-138 T 09-03-2017 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 1.8E-132 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 09-03-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 Gene3D G3DSA:3.30.590.10 108 453 6.6E-136 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 SMART SM01230 104 383 2.2E-152 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 2.6E-23 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10730 266f548f66d5b81fbc8a36348150aea3 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 472 2.6E-193 T 09-03-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 SUPERFAMILY SSF50465 304 396 8.63E-35 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 2.6E-211 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 57.571 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.4E-56 T 09-03-2017 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Gene3D G3DSA:2.40.30.10 214 300 1.9E-36 T 09-03-2017 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 9.8E-13 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Gene3D G3DSA:3.40.50.300 5 213 7.5E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 SUPERFAMILY SSF52540 6 221 1.13E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.5E-16 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Gene3D G3DSA:2.40.30.10 302 395 2.6E-45 T 09-03-2017 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 6.9E-32 T 09-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 SUPERFAMILY SSF50447 207 303 2.29E-30 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 PRINTS PR00315 GTP-binding elongation factor signature 133 142 6.7E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.7E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 PRINTS PR00315 GTP-binding elongation factor signature 96 107 6.7E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 PRINTS PR00315 GTP-binding elongation factor signature 80 90 6.7E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS03475 730a36a103468052ff512a6f0da9015a 396 PRINTS PR00315 GTP-binding elongation factor signature 60 68 6.7E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 146 1.1E-38 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 297 311 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 228 237 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 278 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00101 Aspartate carbamoyltransferase signature 133 150 1.1E-29 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 Gene3D G3DSA:3.40.50.1370 145 295 1.3E-43 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 3.5E-20 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 278 3.5E-20 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 3.5E-20 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 281 304 3.5E-20 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 Gene3D G3DSA:3.40.50.1370 2 144 1.2E-48 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 316 7.6E-86 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 315 6.3E-16 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 318 39.826 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 SUPERFAMILY SSF53671 2 318 1.83E-84 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS08120 4f5ce0622da38c8ea828d548f4dc8483 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 SUPERFAMILY SSF55103 256 530 6.7E-52 T 09-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Gene3D G3DSA:1.10.1060.10 580 673 3.8E-13 T 09-03-2017 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Pfam PF13183 4Fe-4S dicluster domain 581 658 2.7E-10 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 SUPERFAMILY SSF56176 16 280 1.87E-47 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Pfam PF02754 Cysteine-rich domain 759 831 0.017 T 09-03-2017 IPR004017 Cysteine-rich domain ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Pfam PF02754 Cysteine-rich domain 901 958 0.12 T 09-03-2017 IPR004017 Cysteine-rich domain ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Pfam PF01565 FAD binding domain 51 191 2.3E-30 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 SUPERFAMILY SSF46548 576 663 3.4E-11 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 644 655 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Gene3D G3DSA:3.30.465.10 110 194 5.7E-24 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Gene3D G3DSA:3.30.465.10 230 280 5.7E-24 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Gene3D G3DSA:3.30.43.10 12 103 2.1E-20 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Gene3D G3DSA:1.10.45.10 490 525 2.3E-5 T 09-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 ARZXY2_RS09680 2b3fbebd3f54c00827206f5a4df1ea42 988 Pfam PF02913 FAD linked oxidases, C-terminal domain 279 525 2.5E-44 T 09-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 ARZXY2_RS12430 9bc24991f0b3cbca1b4e4b75e2e39a8f 498 Gene3D G3DSA:2.60.200.20 398 494 3.5E-12 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS12430 9bc24991f0b3cbca1b4e4b75e2e39a8f 498 Pfam PF06271 RDD family 103 271 1.8E-17 T 09-03-2017 IPR010432 RDD ARZXY2_RS12430 9bc24991f0b3cbca1b4e4b75e2e39a8f 498 Pfam PF00498 FHA domain 410 489 6.7E-6 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS12430 9bc24991f0b3cbca1b4e4b75e2e39a8f 498 SUPERFAMILY SSF49879 350 494 6.63E-12 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 SUPERFAMILY SSF52172 11 144 2.42E-37 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 Gene3D G3DSA:1.10.10.10 133 228 4.3E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 222 4.5E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 SMART SM00421 165 222 6.4E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 Pfam PF00072 Response regulator receiver domain 14 126 1.6E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 SUPERFAMILY SSF46894 158 228 1.56E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 SMART SM00448 12 125 2.7E-35 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 Gene3D G3DSA:3.40.50.2300 10 132 1.1E-41 T 09-03-2017 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 6.1E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 6.1E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS18740 da2b5383b0c882903bdb7e73f3862e33 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 6.1E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Gene3D G3DSA:3.30.390.30 259 321 1.1E-22 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 82 107 6.2E-31 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 281 6.2E-31 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 217 224 6.2E-31 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 188 6.2E-31 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 56 6.2E-31 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Gene3D G3DSA:3.50.50.60 181 248 2.6E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Gene3D G3DSA:3.50.50.60 4 55 2.6E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Gene3D G3DSA:3.50.50.60 62 180 3.6E-25 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 30 237 3.4E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 264 320 4.1E-16 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 189 1.6E-26 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 82 100 1.6E-26 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 62 1.6E-26 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 202 224 1.6E-26 T 09-03-2017 ARZXY2_RS19345 48cc436c6e69ff99f98ded98b7d781f7 334 SUPERFAMILY SSF51905 42 298 2.27E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 Pfam PF02811 PHP domain 102 191 3.8E-8 T 09-03-2017 IPR004013 PHP domain GO:0003824 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 Pfam PF14716 Helix-hairpin-helix domain 4 70 7.5E-13 T 09-03-2017 IPR010996 DNA polymerase beta-like, N-terminal domain ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 SUPERFAMILY SSF89550 100 338 8.63E-48 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 SMART SM00481 101 180 2.1E-14 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 PIRSF PIRSF036978 1 339 3.2E-155 T 09-03-2017 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 Gene3D G3DSA:1.10.8.310 4 81 7.7E-8 T 09-03-2017 IPR027420 DNA polymerase beta, N-terminal domain ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 Gene3D G3DSA:3.20.20.140 100 337 7.6E-45 T 09-03-2017 ARZXY2_RS11745 1f80462fe14998d54dbc7c8b32bc713f 339 SUPERFAMILY SSF47802 3 82 2.09E-11 T 09-03-2017 IPR010996 DNA polymerase beta-like, N-terminal domain ARZXY2_RS03825 6b94cd5d473c8a75ddd1147d5ed1fef9 195 SUPERFAMILY SSF52540 29 125 7.27E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03825 6b94cd5d473c8a75ddd1147d5ed1fef9 195 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14 138 7.9E-30 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 ARZXY2_RS03825 6b94cd5d473c8a75ddd1147d5ed1fef9 195 Gene3D G3DSA:3.40.50.300 8 183 2.4E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03825 6b94cd5d473c8a75ddd1147d5ed1fef9 195 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 17 141 3.3E-23 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 ARZXY2_RS10435 2dc48a0c0c44ae59a17cdfa112689391 152 SUPERFAMILY SSF82649 4 144 1.15E-30 T 09-03-2017 ARZXY2_RS10435 2dc48a0c0c44ae59a17cdfa112689391 152 Gene3D G3DSA:3.90.1010.10 3 147 7.8E-33 T 09-03-2017 ARZXY2_RS10435 2dc48a0c0c44ae59a17cdfa112689391 152 Pfam PF02657 Fe-S metabolism associated domain 15 143 3.2E-27 T 09-03-2017 IPR003808 Fe-S metabolism associated domain, SufE-like ARZXY2_RS02290 62db0f205311b9d6b5e3699bd9bb207a 201 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 5.7E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS02290 62db0f205311b9d6b5e3699bd9bb207a 201 Gene3D G3DSA:3.40.630.30 4 194 5.5E-59 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS02290 62db0f205311b9d6b5e3699bd9bb207a 201 SUPERFAMILY SSF55729 6 178 4.25E-35 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS06065 ca96ba200349eb537702b3fa3e329c0f 552 SUPERFAMILY SSF56112 94 157 4.28E-29 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS06065 ca96ba200349eb537702b3fa3e329c0f 552 SUPERFAMILY SSF56112 367 425 4.28E-29 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS06065 ca96ba200349eb537702b3fa3e329c0f 552 SUPERFAMILY SSF56112 192 309 4.28E-29 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS06065 ca96ba200349eb537702b3fa3e329c0f 552 Pfam PF03109 ABC1 family 111 229 1.1E-32 T 09-03-2017 IPR004147 UbiB domain ARZXY2_RS06065 ca96ba200349eb537702b3fa3e329c0f 552 Gene3D G3DSA:3.90.1200.10 259 312 3.0E-9 T 09-03-2017 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 Pfam PF13411 MerR HTH family regulatory protein 11 78 1.7E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.9E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.9E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 1.9E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 Gene3D G3DSA:1.10.1660.10 66 122 9.0E-11 T 09-03-2017 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 SUPERFAMILY SSF46955 11 124 2.2E-29 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 Gene3D G3DSA:1.10.1660.10 9 65 3.3E-26 T 09-03-2017 ARZXY2_RS06705 889c3f6e1837b1f594bd0c298d9e14d7 126 SMART SM00422 11 80 3.1E-29 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 SUPERFAMILY SSF57716 229 274 1.06E-9 T 09-03-2017 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 SMART SM00898 2 122 1.3E-17 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 Gene3D G3DSA:3.20.190.10 2 106 6.5E-11 T 09-03-2017 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 SUPERFAMILY SSF81624 2 137 2.09E-21 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 Gene3D G3DSA:1.10.8.50 136 274 2.0E-35 T 09-03-2017 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 SUPERFAMILY SSF46946 135 200 1.77E-19 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 214 5.3E-9 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS15325 a9ead183444c390bb037bdc3e888f974 276 SMART SM01232 136 224 4.8E-24 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS09620 b1e896ecdd8275e16530c5f2aa2e7efc 450 SUPERFAMILY SSF103473 14 427 9.55E-62 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS09620 b1e896ecdd8275e16530c5f2aa2e7efc 450 Gene3D G3DSA:1.20.1250.20 17 218 2.2E-20 T 09-03-2017 ARZXY2_RS09620 b1e896ecdd8275e16530c5f2aa2e7efc 450 Gene3D G3DSA:1.20.1250.20 241 426 1.8E-18 T 09-03-2017 ARZXY2_RS09620 b1e896ecdd8275e16530c5f2aa2e7efc 450 Pfam PF00083 Sugar (and other) transporter 18 226 1.4E-23 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS19285 174af00a2d66b6dfbac03530a9df313d 162 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS19285 174af00a2d66b6dfbac03530a9df313d 162 SUPERFAMILY SSF55811 5 132 1.49E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS19285 174af00a2d66b6dfbac03530a9df313d 162 Gene3D G3DSA:3.90.79.10 3 148 1.8E-23 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS19285 174af00a2d66b6dfbac03530a9df313d 162 Pfam PF00293 NUDIX domain 5 134 8.6E-18 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS00435 57a5f51dc1ec8cd7ec62853ebeddd2f4 403 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 403 75.301 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS00435 57a5f51dc1ec8cd7ec62853ebeddd2f4 403 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 280 1.1E-50 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS00435 57a5f51dc1ec8cd7ec62853ebeddd2f4 403 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 291 5.2E-86 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 ARZXY2_RS00435 57a5f51dc1ec8cd7ec62853ebeddd2f4 403 SUPERFAMILY SSF55931 2 352 2.84E-84 T 09-03-2017 ARZXY2_RS14715 e63d6031d5f5831d5a56ed311220274e 258 Gene3D G3DSA:3.40.50.1240 16 253 1.9E-48 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS14715 e63d6031d5f5831d5a56ed311220274e 258 SMART SM00855 17 190 7.1E-18 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS14715 e63d6031d5f5831d5a56ed311220274e 258 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 18 220 2.7E-35 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS14715 e63d6031d5f5831d5a56ed311220274e 258 SUPERFAMILY SSF53254 17 240 3.18E-46 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS14715 e63d6031d5f5831d5a56ed311220274e 258 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 20 29 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 73 81 4.5E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 103 114 4.5E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 161 175 4.5E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 Gene3D G3DSA:3.40.50.1820 20 264 1.0E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 Gene3D G3DSA:3.40.50.1820 330 441 1.0E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 SUPERFAMILY SSF53474 46 268 4.57E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09145 9cbd85dbc31ae31587fbe517d796d101 448 Pfam PF00561 alpha/beta hydrolase fold 71 203 1.8E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Pfam PF16193 AAA C-terminal domain 182 255 1.1E-22 T 09-03-2017 IPR032423 AAA ATPase, C-terminal domain ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Gene3D G3DSA:3.40.50.300 5 141 3.9E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 SUPERFAMILY SSF48019 241 423 8.08E-76 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Pfam PF12002 MgsA AAA+ ATPase C terminal 256 421 2.0E-70 T 09-03-2017 IPR021886 MgsA AAA+ ATPase C-terminal ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 129 1.0E-16 T 09-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Gene3D G3DSA:1.20.272.10 237 334 1.2E-45 T 09-03-2017 ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Gene3D G3DSA:1.10.3710.10 336 425 5.4E-29 T 09-03-2017 ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 SMART SM00382 40 156 1.8E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 SUPERFAMILY SSF52540 4 224 2.57E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06490 25e24adba876a031cc6b82171ba0548e 433 Gene3D G3DSA:1.10.8.60 142 230 3.0E-10 T 09-03-2017 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 13 942 0.0 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 SUPERFAMILY SSF53383 19 436 1.43E-95 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 Gene3D G3DSA:3.40.640.10 70 298 3.6E-10 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 Pfam PF02347 Glycine cleavage system P-protein 470 726 1.7E-9 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 Pfam PF02347 Glycine cleavage system P-protein 12 437 6.3E-174 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 4 948 24.333 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 SUPERFAMILY SSF53383 921 944 1.15E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 SUPERFAMILY SSF53383 464 878 1.15E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS19585 da1a71b272cce71097a8ec986c65534a 957 Gene3D G3DSA:3.40.640.10 494 726 1.9E-35 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 SUPERFAMILY SSF52425 3 205 2.09E-53 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Gene3D G3DSA:3.40.50.620 2 144 6.7E-46 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Gene3D G3DSA:1.25.40.80 201 276 1.4E-37 T 09-03-2017 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Gene3D G3DSA:1.25.40.80 145 167 1.4E-37 T 09-03-2017 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 SUPERFAMILY SSF48173 191 470 1.83E-96 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Pfam PF00875 DNA photolyase 4 166 9.6E-47 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Gene3D G3DSA:1.10.579.10 330 469 2.0E-67 T 09-03-2017 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Gene3D G3DSA:1.10.579.10 277 286 2.0E-67 T 09-03-2017 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 361 380 - T 09-03-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 PRINTS PR00147 DNA photolyase signature 361 379 1.9E-21 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 PRINTS PR00147 DNA photolyase signature 139 155 1.9E-21 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 PRINTS PR00147 DNA photolyase signature 400 414 1.9E-21 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 PRINTS PR00147 DNA photolyase signature 341 357 1.9E-21 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 ARZXY2_RS16360 6b140c9e54608330ddf83f170e04d856 472 Pfam PF03441 FAD binding domain of DNA photolyase 268 466 2.5E-69 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 ARZXY2_RS00940 7119bb6344baaa772822a4128cb372c0 318 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 32 116 6.7E-14 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin ARZXY2_RS00940 7119bb6344baaa772822a4128cb372c0 318 SUPERFAMILY SSF52980 233 314 6.43E-5 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 Pfam PF02502 Ribose/Galactose Isomerase 3 144 1.4E-39 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 151 7.3E-53 T 09-03-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 PIRSF PIRSF005384 1 152 5.4E-40 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 148 2.3E-28 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 Gene3D G3DSA:3.40.1400.10 1 150 7.6E-44 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS18865 aa8c447e2df15f627bbd01919575b54d 152 SUPERFAMILY SSF89623 1 150 4.71E-43 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 165 5.4E-12 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 SUPERFAMILY SSF88659 106 164 9.53E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 Pfam PF08281 Sigma-70, region 4 111 161 7.5E-9 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 SUPERFAMILY SSF88946 6 75 1.22E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 Gene3D G3DSA:1.10.10.10 106 165 7.7E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 Pfam PF04542 Sigma-70 region 2 13 78 1.6E-8 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00545 40376f1f23dd533ed94889265a999a18 418 Gene3D G3DSA:1.10.1740.10 9 103 2.7E-10 T 09-03-2017 ARZXY2_RS05355 7e485f8f3dbc95a8b510be245582e74e 208 Pfam PF00857 Isochorismatase family 4 204 2.0E-27 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS05355 7e485f8f3dbc95a8b510be245582e74e 208 SUPERFAMILY SSF52499 2 110 6.73E-43 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS05355 7e485f8f3dbc95a8b510be245582e74e 208 SUPERFAMILY SSF52499 138 191 6.73E-43 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS05355 7e485f8f3dbc95a8b510be245582e74e 208 Gene3D G3DSA:3.40.50.850 1 205 3.5E-56 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 SUPERFAMILY SSF50494 136 286 1.25E-26 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 SUPERFAMILY SSF50494 25 108 1.25E-26 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 Gene3D G3DSA:2.40.10.10 77 97 5.9E-4 T 09-03-2017 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 Gene3D G3DSA:2.40.10.10 139 194 5.9E-4 T 09-03-2017 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 Gene3D G3DSA:2.40.10.10 195 287 3.8E-13 T 09-03-2017 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 PRINTS PR00834 HtrA/DegQ protease family signature 254 271 1.0E-5 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 1.0E-5 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 PRINTS PR00834 HtrA/DegQ protease family signature 87 99 1.0E-5 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01300 94aa6c581491ecf238687d2b37885098 386 Pfam PF13365 Trypsin-like peptidase domain 78 261 8.0E-17 T 09-03-2017 ARZXY2_RS04320 b0132c870b5c091fe023468ef6995237 110 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 51 82 3.6E-10 T 09-03-2017 IPR019933 DivIVA domain ARZXY2_RS04320 b0132c870b5c091fe023468ef6995237 110 Pfam PF05103 DivIVA protein 52 101 1.1E-5 T 09-03-2017 IPR007793 DivIVA family ARZXY2_RS14645 2e1007cc226bf5260e47b4d06967cc65 341 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 5 338 4.5E-105 T 09-03-2017 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 ARZXY2_RS14645 2e1007cc226bf5260e47b4d06967cc65 341 Gene3D G3DSA:3.75.10.10 2 339 2.7E-116 T 09-03-2017 ARZXY2_RS14645 2e1007cc226bf5260e47b4d06967cc65 341 SUPERFAMILY SSF55909 2 339 4.28E-114 T 09-03-2017 ARZXY2_RS19340 4e7916157c4562521408314f4c180ad1 437 Pfam PF13700 Domain of unknown function (DUF4158) 13 169 9.3E-24 T 09-03-2017 IPR025296 Domain of unknown function DUF4158 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 Gene3D G3DSA:3.30.420.40 293 320 4.0E-5 T 09-03-2017 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 Pfam PF01968 Hydantoinase/oxoprolinase 216 503 3.5E-69 T 09-03-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 14 195 3.0E-47 T 09-03-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 SUPERFAMILY SSF53067 275 359 3.46E-9 T 09-03-2017 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 SUPERFAMILY SSF53067 13 90 3.46E-9 T 09-03-2017 ARZXY2_RS09755 5d6a019b9fe19dcc6cf6ae1273648d9c 696 SUPERFAMILY SSF53067 410 496 3.46E-9 T 09-03-2017 ARZXY2_RS18415 e3a4b09aa65407e027ce7acbd1c7a390 245 Gene3D G3DSA:2.60.200.20 154 241 2.3E-25 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS18415 e3a4b09aa65407e027ce7acbd1c7a390 245 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 5.4E-36 T 09-03-2017 IPR022128 Protein of unknown function DUF3662 ARZXY2_RS18415 e3a4b09aa65407e027ce7acbd1c7a390 245 SUPERFAMILY SSF49879 130 237 3.25E-26 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS18415 e3a4b09aa65407e027ce7acbd1c7a390 245 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 154 234 4.3E-18 T 09-03-2017 IPR032030 YscD, cytoplasmic domain ARZXY2_RS18415 e3a4b09aa65407e027ce7acbd1c7a390 245 SMART SM00240 163 213 2.3E-13 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS01635 be64d0d80790d4bdeb174dd345b07a12 63 Pfam PF07411 Domain of unknown function (DUF1508) 15 57 9.5E-9 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS01635 be64d0d80790d4bdeb174dd345b07a12 63 Gene3D G3DSA:3.30.160.160 4 49 1.5E-8 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS01635 be64d0d80790d4bdeb174dd345b07a12 63 SUPERFAMILY SSF160113 3 59 2.09E-13 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Pfam PF03572 Peptidase family S41 971 1127 2.9E-20 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Pfam PF14685 Tricorn protease PDZ domain 849 929 5.7E-20 T 09-03-2017 IPR029414 Tricorn protease, PDZ domain ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF52096 768 846 7.12E-63 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF52096 944 1154 7.12E-63 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:2.120.10.60 2 250 1.3E-53 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SMART SM00245 935 1128 1.4E-17 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF69304 6 261 1.07E-29 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Pfam PF14684 Tricorn protease C1 domain 770 836 1.6E-26 T 09-03-2017 IPR028204 Tricorn protease C1 domain ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:3.90.226.10 952 1156 1.1E-36 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:2.130.10.10 251 278 5.2E-67 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:2.130.10.10 335 361 5.2E-67 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:2.130.10.10 460 750 5.2E-67 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:3.30.750.44 767 837 1.8E-28 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF69322 466 649 2.62E-21 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF69322 242 267 2.62E-21 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF69322 324 367 2.62E-21 T 09-03-2017 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Gene3D G3DSA:2.30.42.10 848 948 3.9E-22 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 SUPERFAMILY SSF50156 849 929 4.51E-12 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Pfam PF07676 WD40-like Beta Propeller Repeat 565 587 0.0031 T 09-03-2017 IPR011659 WD40-like Beta Propeller ARZXY2_RS10695 bfe7cfdeefbfe3577e5eeca9ed6899fd 1182 Pfam PF07676 WD40-like Beta Propeller Repeat 44 61 0.0097 T 09-03-2017 IPR011659 WD40-like Beta Propeller ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Pfam PF08245 Mur ligase middle domain 119 310 3.0E-39 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 466 2.3E-116 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 SUPERFAMILY SSF53623 114 326 9.55E-47 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Pfam PF01225 Mur ligase family, catalytic domain 27 97 1.9E-9 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 SUPERFAMILY SSF53244 333 467 1.44E-34 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Gene3D G3DSA:3.90.190.20 331 471 9.0E-39 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Gene3D G3DSA:3.40.1390.10 1 78 9.7E-22 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 SUPERFAMILY SSF63418 1 99 1.7E-21 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 472 30.132 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 416 9.2E-19 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10865 92a449c469d5eeec8a4759b5ecac4c28 496 Gene3D G3DSA:3.40.1190.10 87 326 1.1E-60 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 Pfam PF13185 GAF domain 75 177 6.3E-9 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 SMART SM01012 189 244 1.2E-20 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 PIRSF PIRSF036625 20 255 1.2E-38 T 09-03-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 SUPERFAMILY SSF55781 65 188 2.11E-16 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 SUPERFAMILY SSF52172 174 244 1.19E-8 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 Gene3D G3DSA:1.10.10.10 193 247 3.7E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 Gene3D G3DSA:3.30.450.40 62 192 1.6E-11 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17210 6bf9f65af298d14368c9e169aff61bc7 258 Pfam PF03861 ANTAR domain 191 244 2.8E-16 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS10320 84abc003a92833736f86b60e32458de5 234 SUPERFAMILY SSF142695 25 188 1.22E-54 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ARZXY2_RS10320 84abc003a92833736f86b60e32458de5 234 Pfam PF00925 GTP cyclohydrolase II 26 186 1.0E-59 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ARZXY2_RS10320 84abc003a92833736f86b60e32458de5 234 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 17 213 37.709 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ARZXY2_RS10320 84abc003a92833736f86b60e32458de5 234 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 26 210 1.3E-66 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 ARZXY2_RS00690 bf883b3d92b1082ab2ef71373ff74781 259 SUPERFAMILY SSF52499 13 242 5.23E-56 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS00690 bf883b3d92b1082ab2ef71373ff74781 259 Pfam PF00857 Isochorismatase family 46 225 3.6E-30 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS00690 bf883b3d92b1082ab2ef71373ff74781 259 Gene3D G3DSA:3.40.50.850 21 237 2.3E-54 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 4.9E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 4.9E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 SUPERFAMILY SSF48498 106 162 1.14E-5 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 Gene3D G3DSA:1.10.357.10 35 217 6.3E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 84 2.9E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15185 6b17037636c240dd97b310b460ec4028 221 SUPERFAMILY SSF46689 28 110 9.98E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11945 0a8cf2ec2c51a237935478f7eb9d0973 253 Pfam PF04586 Caudovirus prohead serine protease 20 169 5.9E-33 T 09-03-2017 IPR006433 Prohead protease ARZXY2_RS11945 0a8cf2ec2c51a237935478f7eb9d0973 253 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 22 165 4.3E-40 T 09-03-2017 IPR006433 Prohead protease ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 49 273 2.0E-49 T 09-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 28 319 5.6E-135 T 09-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 Gene3D G3DSA:3.40.50.620 260 268 1.1E-53 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 Gene3D G3DSA:3.40.50.620 22 227 1.1E-53 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 SUPERFAMILY SSF52402 26 227 4.89E-66 T 09-03-2017 ARZXY2_RS02855 906892afff3ce029004a02841f635d5e 319 PIRSF PIRSF002936 19 319 4.8E-134 T 09-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 Gene3D G3DSA:3.20.20.120 115 354 1.5E-78 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 Pfam PF13378 Enolase C-terminal domain-like 135 357 3.7E-59 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 Gene3D G3DSA:3.30.390.10 1 114 1.0E-35 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 SUPERFAMILY SSF54826 1 115 1.61E-25 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 110 4.0E-18 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 SUPERFAMILY SSF51604 98 364 1.44E-77 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS17320 cf7e06f1cecd41d269ff25b0d0bd5240 395 SMART SM00922 131 236 2.4E-23 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS02325 bc073929ddf96d3efe442ace65c135cd 153 Gene3D G3DSA:3.10.129.10 10 153 4.5E-45 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02325 bc073929ddf96d3efe442ace65c135cd 153 Pfam PF03061 Thioesterase superfamily 49 127 7.2E-9 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS02325 bc073929ddf96d3efe442ace65c135cd 153 SUPERFAMILY SSF54637 12 150 3.74E-25 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02325 bc073929ddf96d3efe442ace65c135cd 153 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 126 1.4E-19 T 09-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 ARZXY2_RS09785 b0f9f14788fa30fc9163b14342368265 217 Gene3D G3DSA:1.10.357.10 29 209 3.5E-25 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS09785 b0f9f14788fa30fc9163b14342368265 217 SUPERFAMILY SSF46689 29 95 8.48E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09785 b0f9f14788fa30fc9163b14342368265 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 SMART SM01409 15 79 9.0E-11 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 8 80 13.146 T 09-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 9 77 1.1E-18 T 09-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 Gene3D G3DSA:3.90.940.10 8 83 1.2E-30 T 09-03-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 SUPERFAMILY SSF63562 8 83 1.66E-23 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ARZXY2_RS08160 92d9f06a8447e5c49c2dd21a25df7e2a 86 Pfam PF01192 RNA polymerase Rpb6 16 77 2.4E-11 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Pfam PF00384 Molybdopterin oxidoreductase 97 521 2.4E-68 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Pfam PF01568 Molydopterin dinucleotide binding domain 650 771 4.2E-28 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 SMART SM00926 39 94 8.7E-12 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 SUPERFAMILY SSF53706 40 598 1.57E-166 T 09-03-2017 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 471 488 - T 09-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Gene3D G3DSA:3.40.50.740 99 301 2.4E-40 T 09-03-2017 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 689 716 - T 09-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 SUPERFAMILY SSF50692 632 778 2.94E-41 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Gene3D G3DSA:2.20.25.90 40 98 7.5E-13 T 09-03-2017 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Gene3D G3DSA:2.40.40.20 586 778 4.7E-50 T 09-03-2017 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 40 87 1.2E-7 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Gene3D G3DSA:3.40.50.740 302 379 8.2E-50 T 09-03-2017 ARZXY2_RS19745 5f03994e4635a2554a53fab7537b2783 800 Gene3D G3DSA:3.40.50.740 412 585 8.2E-50 T 09-03-2017 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Gene3D G3DSA:2.40.50.100 516 585 3.0E-23 T 09-03-2017 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Gene3D G3DSA:3.30.1490.20 129 201 3.2E-21 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 SMART SM00878 334 443 2.4E-56 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Gene3D G3DSA:3.40.50.20 2 128 5.6E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Pfam PF02785 Biotin carboxylase C-terminal domain 334 443 9.1E-37 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 5.1E-42 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 541 558 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 SUPERFAMILY SSF51246 330 445 1.05E-34 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 SUPERFAMILY SSF51230 515 585 6.67E-21 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Pfam PF00364 Biotin-requiring enzyme 523 584 1.4E-16 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 8.3E-73 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 Gene3D G3DSA:3.30.470.20 203 446 5.3E-90 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 SUPERFAMILY SSF52440 2 112 1.22E-45 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS18320 aa84761e4bcddb8e23b339fe35096fe0 585 SUPERFAMILY SSF56059 82 326 3.54E-60 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Gene3D G3DSA:2.40.40.20 558 711 2.3E-40 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 SUPERFAMILY SSF50692 562 711 4.52E-40 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Gene3D G3DSA:2.20.25.90 5 72 7.9E-16 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 SMART SM00926 2 72 0.0011 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Gene3D G3DSA:3.40.228.10 152 338 3.5E-47 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Pfam PF00384 Molybdopterin oxidoreductase 75 508 1.1E-70 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Gene3D G3DSA:3.40.50.740 339 557 4.3E-69 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Gene3D G3DSA:3.40.50.740 75 151 4.3E-69 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Pfam PF01568 Molydopterin dinucleotide binding domain 598 703 3.5E-32 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 SUPERFAMILY SSF53706 6 584 4.19E-149 T 09-03-2017 ARZXY2_RS12540 85ce8f611547c3069367d730be6fd1ee 733 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 71 5.8E-6 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS04100 0d5d4c618986a81f942fd6a5366434ca 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 212 2.1E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04100 0d5d4c618986a81f942fd6a5366434ca 248 SUPERFAMILY SSF161098 22 206 4.32E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04100 0d5d4c618986a81f942fd6a5366434ca 248 Gene3D G3DSA:1.10.3720.10 27 211 2.8E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 09-03-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 SMART SM01403 7 101 7.4E-55 T 09-03-2017 IPR027486 Ribosomal protein S10 domain ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.0E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.0E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.0E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.2E-45 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 SUPERFAMILY SSF54999 5 102 3.14E-37 T 09-03-2017 IPR027486 Ribosomal protein S10 domain ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.086 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 Gene3D G3DSA:3.30.70.600 4 102 1.3E-42 T 09-03-2017 IPR027486 Ribosomal protein S10 domain ARZXY2_RS03490 136caca3914a5d85dc58d6fc76ec4c4e 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-34 T 09-03-2017 IPR027486 Ribosomal protein S10 domain ARZXY2_RS17735 1474262b01b6a332bc12cf8cf0c2c847 458 Pfam PF06965 Na+/H+ antiporter 1 27 413 1.3E-129 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS17735 1474262b01b6a332bc12cf8cf0c2c847 458 Gene3D G3DSA:1.20.1530.10 25 419 3.3E-132 T 09-03-2017 IPR023171 Na/H antiporter domain ARZXY2_RS17735 1474262b01b6a332bc12cf8cf0c2c847 458 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 28 412 1.3E-97 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS17735 1474262b01b6a332bc12cf8cf0c2c847 458 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 24 419 20.659 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS11645 0b014853a817b3f86539210954922778 309 Gene3D G3DSA:1.10.3720.10 19 295 3.7E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11645 0b014853a817b3f86539210954922778 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 295 1.8E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11645 0b014853a817b3f86539210954922778 309 SUPERFAMILY SSF161098 68 291 7.46E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:3.30.2090.10 182 265 4.1E-4 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82866 797 1028 1.07E-49 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82693 265 320 5.23E-11 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82693 134 180 5.23E-11 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:1.10.3850.10 803 1024 1.2E-59 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:3.30.2090.10 716 796 9.9E-7 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Pfam PF00873 AcrB/AcrD/AcrF family 6 1022 1.3E-210 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82693 41 129 4.19E-23 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:3.30.70.1430 41 141 1.6E-27 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82866 289 487 1.57E-43 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:1.20.1640.10 297 489 1.3E-54 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 SUPERFAMILY SSF82714 716 795 1.03E-7 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:3.30.70.1320 267 296 5.9E-6 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 Gene3D G3DSA:3.30.70.1320 161 177 5.9E-6 T 09-03-2017 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05570 d44e5305b9bebb84d35ae94d97bd4aa3 1073 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 1.0E-42 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS18425 22cc2346ff5e57ff55a74291231e24fa 571 SMART SM00332 11 250 3.2E-17 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS18425 22cc2346ff5e57ff55a74291231e24fa 571 Pfam PF13672 Protein phosphatase 2C 34 225 9.2E-12 T 09-03-2017 ARZXY2_RS18425 22cc2346ff5e57ff55a74291231e24fa 571 SMART SM00331 26 252 1.4E-26 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS18425 22cc2346ff5e57ff55a74291231e24fa 571 SUPERFAMILY SSF81606 19 250 9.02E-59 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS18425 22cc2346ff5e57ff55a74291231e24fa 571 Gene3D G3DSA:3.60.40.10 18 252 3.7E-63 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 257 3.3E-53 T 09-03-2017 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 SUPERFAMILY SSF51621 3 294 2.92E-97 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 09-03-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 Gene3D G3DSA:3.20.20.60 10 291 2.3E-94 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 294 7.2E-122 T 09-03-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 ARZXY2_RS11085 87892deca918ee8c29aaf76c1552dea8 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 46.197 T 09-03-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Gene3D G3DSA:2.70.150.10 129 243 3.0E-37 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Gene3D G3DSA:2.70.150.10 28 68 3.0E-37 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Pfam PF00689 Cation transporting ATPase, C-terminus 757 932 2.8E-51 T 09-03-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Pfam PF00690 Cation transporter/ATPase, N-terminus 16 84 6.7E-18 T 09-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Gene3D G3DSA:1.20.1110.10 69 128 1.4E-115 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Gene3D G3DSA:1.20.1110.10 629 934 1.4E-115 T 09-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF81653 135 243 1.31E-25 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Pfam PF00122 E1-E2 ATPase 101 339 2.1E-59 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Gene3D G3DSA:3.40.1110.10 338 565 7.1E-52 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SMART SM00831 15 89 1.3E-22 T 09-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 Pfam PF00702 haloacid dehalogenase-like hydrolase 346 674 1.0E-22 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF81665 15 134 7.19E-122 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF81665 244 342 7.19E-122 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF81665 710 938 7.19E-122 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF81660 355 562 5.67E-46 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 684 696 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 348 362 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 590 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 181 195 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 569 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 660 679 1.7E-36 T 09-03-2017 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 627 741 1.8E-32 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 102 369 2.4E-35 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF56784 346 366 2.94E-56 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 SUPERFAMILY SSF56784 510 777 2.94E-56 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 692 717 3.9E-16 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 513 531 3.9E-16 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 3.9E-16 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 660 676 3.9E-16 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS06030 abf4e35f768c5df8f2198ca71105667b 947 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 350 356 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS03860 4239ce1b28525b218b5a79906604f626 265 SUPERFAMILY SSF53223 3 97 1.38E-24 T 09-03-2017 ARZXY2_RS03860 4239ce1b28525b218b5a79906604f626 265 SUPERFAMILY SSF51735 98 257 3.12E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03860 4239ce1b28525b218b5a79906604f626 265 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 17 85 3.0E-15 T 09-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 ARZXY2_RS03860 4239ce1b28525b218b5a79906604f626 265 Gene3D G3DSA:3.40.50.720 103 258 4.1E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03860 4239ce1b28525b218b5a79906604f626 265 Gene3D G3DSA:3.40.192.10 17 102 1.4E-26 T 09-03-2017 ARZXY2_RS03315 e5580fca1b2ee77f4fac7395fac4e60a 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 2.4E-29 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS03315 e5580fca1b2ee77f4fac7395fac4e60a 232 SUPERFAMILY SSF46894 123 219 2.18E-31 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS03315 e5580fca1b2ee77f4fac7395fac4e60a 232 SMART SM00862 145 219 1.6E-30 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS03315 e5580fca1b2ee77f4fac7395fac4e60a 232 Gene3D G3DSA:1.10.10.10 122 220 6.0E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05035 d61f659a512569af2ffeb63ba3f8da47 86 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 2 84 9.7E-30 T 09-03-2017 IPR014295 Anti-sigma factor ARZXY2_RS05035 d61f659a512569af2ffeb63ba3f8da47 86 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 9 82 7.2E-28 T 09-03-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA ARZXY2_RS05035 d61f659a512569af2ffeb63ba3f8da47 86 Pfam PF13490 Putative zinc-finger 15 44 5.2E-9 T 09-03-2017 IPR027383 Putative zinc-finger ARZXY2_RS08640 d62b68776b04d257d84a1983bca19331 454 Pfam PF03136 Pup-ligase protein 4 423 6.7E-155 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 ARZXY2_RS08640 d62b68776b04d257d84a1983bca19331 454 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.986 T 09-03-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 ARZXY2_RS08640 d62b68776b04d257d84a1983bca19331 454 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.4E-234 T 09-03-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 ARZXY2_RS08640 d62b68776b04d257d84a1983bca19331 454 PIRSF PIRSF018077 1 454 5.3E-171 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 ARZXY2_RS08895 2ff2ddc43511d852877914b5dd62c037 261 SUPERFAMILY SSF52540 4 236 3.9E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08895 2ff2ddc43511d852877914b5dd62c037 261 SMART SM00382 29 230 2.5E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08895 2ff2ddc43511d852877914b5dd62c037 261 Pfam PF00005 ABC transporter 20 171 2.2E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08895 2ff2ddc43511d852877914b5dd62c037 261 Gene3D G3DSA:3.40.50.300 3 239 1.9E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00555 d84b85cd1c9f7ecaad871e6183ef01bc 271 Pfam PF13847 Methyltransferase domain 40 165 1.0E-30 T 09-03-2017 IPR025714 Methyltransferase domain ARZXY2_RS00555 d84b85cd1c9f7ecaad871e6183ef01bc 271 Gene3D G3DSA:3.40.50.150 8 227 2.0E-47 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS00555 d84b85cd1c9f7ecaad871e6183ef01bc 271 SUPERFAMILY SSF53335 8 219 1.7E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 892 163.544 T 09-03-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 SUPERFAMILY SSF101353 249 451 1.7E-53 T 09-03-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 Pfam PF02272 DHHA1 domain 818 885 2.5E-9 T 09-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 SMART SM00863 666 710 3.3E-17 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 666 710 9.3E-15 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 Pfam PF01411 tRNA synthetases class II (A) 5 569 3.2E-186 T 09-03-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 872 1.3E-252 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 310 323 1.6E-29 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.6E-29 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.6E-29 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.6E-29 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 286 302 1.6E-29 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 Gene3D G3DSA:3.30.930.10 1 244 1.8E-92 T 09-03-2017 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 SUPERFAMILY SSF55186 565 724 1.28E-39 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 SUPERFAMILY SSF50447 467 564 2.12E-15 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain ARZXY2_RS08060 6046df52f2a3ad216202143715f15664 892 SUPERFAMILY SSF55681 2 248 2.61E-86 T 09-03-2017 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Gene3D G3DSA:3.30.1270.10 213 248 6.4E-37 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Gene3D G3DSA:3.30.1270.10 83 137 6.4E-37 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Gene3D G3DSA:3.30.70.980 138 205 6.5E-25 T 09-03-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 SUPERFAMILY SSF75625 3 246 2.22E-87 T 09-03-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 33.784 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Gene3D G3DSA:1.10.10.200 1 77 2.4E-31 T 09-03-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 1.2E-92 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS07965 76d6fcad51e2a377cb8a2c7eb33561ee 251 Pfam PF01709 Transcriptional regulator 5 238 8.3E-86 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 PIRSF PIRSF038945 1 363 2.2E-154 T 09-03-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 TIGRFAM TIGR00260 thrC: threonine synthase 11 334 1.6E-89 T 09-03-2017 IPR004450 Threonine synthase-like ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 Gene3D G3DSA:3.40.50.1100 146 337 3.1E-44 T 09-03-2017 ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 SUPERFAMILY SSF53686 6 347 4.32E-104 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 328 4.9E-73 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 Gene3D G3DSA:3.40.50.1100 61 145 1.7E-41 T 09-03-2017 ARZXY2_RS05175 a3b1c5eb15eb332dd742b924efa08328 367 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 09-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 ARZXY2_RS01145 16b4c7c201aa705a4e3c4b4078d4120d 169 SUPERFAMILY SSF158694 3 162 2.49E-44 T 09-03-2017 ARZXY2_RS01145 16b4c7c201aa705a4e3c4b4078d4120d 169 Gene3D G3DSA:1.10.3330.10 11 164 1.1E-45 T 09-03-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 ARZXY2_RS01145 16b4c7c201aa705a4e3c4b4078d4120d 169 Pfam PF09349 OHCU decarboxylase 7 159 2.7E-40 T 09-03-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 ARZXY2_RS01145 16b4c7c201aa705a4e3c4b4078d4120d 169 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 6 163 4.8E-66 T 09-03-2017 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 ARZXY2_RS11705 14e87a678c96a575f801f29e432278a9 536 SUPERFAMILY SSF52096 237 518 2.05E-86 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS11705 14e87a678c96a575f801f29e432278a9 536 Pfam PF01039 Carboxyl transferase domain 48 524 1.0E-149 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS11705 14e87a678c96a575f801f29e432278a9 536 Gene3D G3DSA:3.90.226.10 282 531 4.0E-91 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS11705 14e87a678c96a575f801f29e432278a9 536 Gene3D G3DSA:3.90.226.10 28 268 1.3E-77 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS11705 14e87a678c96a575f801f29e432278a9 536 SUPERFAMILY SSF52096 25 270 1.24E-72 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS03650 dee9543e959ebe31a3f1d1562de731b2 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.187 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 ARZXY2_RS03650 dee9543e959ebe31a3f1d1562de731b2 73 SUPERFAMILY SSF50249 4 72 4.0E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03650 dee9543e959ebe31a3f1d1562de731b2 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 3.9E-37 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 ARZXY2_RS03650 dee9543e959ebe31a3f1d1562de731b2 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 7.6E-29 T 09-03-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 ARZXY2_RS03650 dee9543e959ebe31a3f1d1562de731b2 73 Gene3D G3DSA:2.40.50.140 2 73 1.5E-39 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS18595 da58276af4f000ea59930e623f1ac15e 216 Gene3D G3DSA:3.40.50.150 20 209 9.0E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS18595 da58276af4f000ea59930e623f1ac15e 216 SUPERFAMILY SSF53335 18 206 5.79E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS18595 da58276af4f000ea59930e623f1ac15e 216 Pfam PF02527 rRNA small subunit methyltransferase G 22 196 1.2E-48 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ARZXY2_RS18595 da58276af4f000ea59930e623f1ac15e 216 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 12 206 22.461 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ARZXY2_RS18595 da58276af4f000ea59930e623f1ac15e 216 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 24 193 4.5E-39 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 ARZXY2_RS13055 799cd1ca2f11bc98f89be34218ba8bde 307 Pfam PF12811 Bax inhibitor 1 like 62 304 2.7E-83 T 09-03-2017 IPR010539 Protein of unknown function UCP009160 ARZXY2_RS13055 799cd1ca2f11bc98f89be34218ba8bde 307 PIRSF PIRSF009160 1 307 6.1E-72 T 09-03-2017 IPR010539 Protein of unknown function UCP009160 ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 SUPERFAMILY SSF53448 10 263 2.5E-53 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Gene3D G3DSA:2.160.10.10 344 460 5.0E-28 T 09-03-2017 ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 406 440 7.1E-5 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 10 463 4.8E-158 T 09-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Gene3D G3DSA:3.90.550.10 9 256 3.2E-69 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 SUPERFAMILY SSF51161 260 461 6.04E-40 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 8 463 37.397 T 09-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Gene3D G3DSA:2.160.10.10 257 343 5.5E-15 T 09-03-2017 ARZXY2_RS12775 378234f72ae9331bbd867d804946d65c 499 Pfam PF12804 MobA-like NTP transferase domain 11 142 6.6E-19 T 09-03-2017 IPR025877 MobA-like NTP transferase ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 SMART SM00363 95 156 1.7E-14 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 SMART SM01390 8 94 6.5E-36 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 Pfam PF01479 S4 domain 95 142 6.7E-17 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 93 117 - T 09-03-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 6 206 30.385 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 10 206 5.8E-63 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 SUPERFAMILY SSF55174 12 206 5.06E-52 T 09-03-2017 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 Gene3D G3DSA:3.10.290.10 98 197 2.0E-22 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 9 94 1.9E-19 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 ARZXY2_RS08045 c527a3dac0fbff934ef2185336c936d9 206 Gene3D G3DSA:1.10.1050.10 10 97 3.5E-31 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 Pfam PF04954 Siderophore-interacting protein 174 346 7.7E-44 T 09-03-2017 IPR007037 Siderophore-interacting protein ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 Gene3D G3DSA:3.40.50.80 171 251 3.5E-46 T 09-03-2017 ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 Gene3D G3DSA:3.40.50.80 300 349 3.5E-46 T 09-03-2017 ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 Gene3D G3DSA:2.40.30.10 19 153 9.8E-30 T 09-03-2017 ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 Pfam PF08021 Siderophore-interacting FAD-binding domain 24 154 4.0E-30 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 SUPERFAMILY SSF63380 94 154 5.3E-11 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS20590 056c097dedd29e0a8ee99240b2a701e9 350 SUPERFAMILY SSF63380 20 66 5.3E-11 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS12820 a0c75ce3c3ad6d882a95bb13acf1209e 373 Gene3D G3DSA:1.10.8.300 248 355 6.5E-32 T 09-03-2017 ARZXY2_RS12820 a0c75ce3c3ad6d882a95bb13acf1209e 373 PIRSF PIRSF002849 25 361 5.7E-128 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted ARZXY2_RS12820 a0c75ce3c3ad6d882a95bb13acf1209e 373 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 87 216 5.2E-63 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 ARZXY2_RS12820 a0c75ce3c3ad6d882a95bb13acf1209e 373 SUPERFAMILY SSF52540 74 331 7.85E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12820 a0c75ce3c3ad6d882a95bb13acf1209e 373 Gene3D G3DSA:3.40.50.300 75 233 5.4E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13175 c1ff09750ce2cb9f88171ab722febfcf 355 SUPERFAMILY SSF53822 46 287 9.66E-13 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS13175 c1ff09750ce2cb9f88171ab722febfcf 355 Pfam PF02608 Basic membrane protein 38 346 4.5E-45 T 09-03-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 ARZXY2_RS13175 c1ff09750ce2cb9f88171ab722febfcf 355 Gene3D G3DSA:3.40.50.2300 31 154 1.8E-41 T 09-03-2017 ARZXY2_RS13175 c1ff09750ce2cb9f88171ab722febfcf 355 Gene3D G3DSA:3.40.50.2300 155 317 1.4E-40 T 09-03-2017 ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 Gene3D G3DSA:1.10.10.10 20 92 6.5E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 SMART SM00346 20 107 7.5E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 Gene3D G3DSA:3.30.450.40 93 244 9.0E-24 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 Pfam PF01614 Bacterial transcriptional regulator 158 240 1.5E-4 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 Pfam PF09339 IclR helix-turn-helix domain 22 72 9.5E-14 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 SUPERFAMILY SSF46785 21 91 9.11E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05460 ff7db3a742acba483a1c0f5c944908b3 245 SUPERFAMILY SSF55781 82 244 3.86E-25 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 Gene3D G3DSA:2.40.50.100 7 121 1.0E-42 T 09-03-2017 ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 124 27.929 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 SUPERFAMILY SSF51230 6 120 4.58E-37 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 Pfam PF01597 Glycine cleavage H-protein 8 120 6.0E-39 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS14390 f23412046f7fb92f7e3f5788f2592328 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 119 1.5E-41 T 09-03-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 ARZXY2_RS20470 8dd0d10f0cbe8acfbc7cd06e7febc499 284 Gene3D G3DSA:3.40.1440.10 181 284 1.9E-16 T 09-03-2017 IPR027299 GIY-YIG domain ARZXY2_RS20470 8dd0d10f0cbe8acfbc7cd06e7febc499 284 SUPERFAMILY SSF82771 182 229 1.44E-5 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 PIRSF PIRSF006171 2 237 3.6E-62 T 09-03-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 Pfam PF08220 DeoR-like helix-turn-helix domain 185 219 2.6E-5 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 Gene3D G3DSA:1.10.10.10 178 220 8.5E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 SUPERFAMILY SSF52172 1 129 1.21E-28 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 Pfam PF00072 Response regulator receiver domain 6 121 7.5E-19 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 SMART SM00448 4 122 2.7E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 Gene3D G3DSA:3.40.50.2300 2 125 5.8E-25 T 09-03-2017 ARZXY2_RS11070 b3c1b35fd06dda8786853ea9fb4dcbcc 237 SUPERFAMILY SSF46785 173 223 7.55E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10205 0a6f4fcf2321d6adcd792697ba0b25ae 348 SUPERFAMILY SSF51726 7 342 1.7E-69 T 09-03-2017 ARZXY2_RS10205 0a6f4fcf2321d6adcd792697ba0b25ae 348 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 327 3.4E-39 T 09-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ARZXY2_RS10205 0a6f4fcf2321d6adcd792697ba0b25ae 348 PIRSF PIRSF005632 1 344 1.3E-189 T 09-03-2017 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit ARZXY2_RS10205 0a6f4fcf2321d6adcd792697ba0b25ae 348 Gene3D G3DSA:3.20.20.210 2 341 1.5E-87 T 09-03-2017 ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Pfam PF07731 Multicopper oxidase 379 483 5.7E-25 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 SUPERFAMILY SSF49503 359 483 1.16E-29 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Gene3D G3DSA:2.60.40.420 357 483 6.8E-36 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 SUPERFAMILY SSF49503 186 316 2.34E-22 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Gene3D G3DSA:2.60.40.420 177 319 1.9E-28 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Gene3D G3DSA:2.60.40.420 48 176 1.3E-29 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 ProSitePatterns PS00080 Multicopper oxidases signature 2. 466 477 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Pfam PF07732 Multicopper oxidase 69 179 9.3E-23 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 Pfam PF00394 Multicopper oxidase 208 294 5.3E-9 T 09-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 ARZXY2_RS10120 8fc8889909fff31811638b7b33948b5d 484 SUPERFAMILY SSF49503 55 181 7.18E-29 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS15220 37bf89a497717a6d34002370319be73f 463 SUPERFAMILY SSF53383 6 459 1.28E-108 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS15220 37bf89a497717a6d34002370319be73f 463 Gene3D G3DSA:3.40.640.10 85 353 3.6E-82 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS15220 37bf89a497717a6d34002370319be73f 463 Gene3D G3DSA:1.20.1340.10 19 82 9.9E-5 T 09-03-2017 ARZXY2_RS15220 37bf89a497717a6d34002370319be73f 463 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 47 397 1.7E-39 T 09-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 ARZXY2_RS15220 37bf89a497717a6d34002370319be73f 463 Gene3D G3DSA:3.90.1150.10 354 458 9.7E-17 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS00065 8dc46122369a207c094864de955da870 172 Pfam PF00583 Acetyltransferase (GNAT) family 72 147 4.1E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS00065 8dc46122369a207c094864de955da870 172 Gene3D G3DSA:3.40.630.30 22 168 3.5E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS00065 8dc46122369a207c094864de955da870 172 SUPERFAMILY SSF55729 16 148 2.23E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 Gene3D G3DSA:2.40.100.10 100 265 6.9E-43 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 Gene3D G3DSA:3.30.1360.40 13 91 2.0E-15 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 SUPERFAMILY SSF50891 100 257 1.55E-26 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 SUPERFAMILY SSF160467 12 105 1.57E-17 T 09-03-2017 ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 SMART SM00796 11 232 2.6E-66 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS13750 f1de8429e42f5adb326d783d49d99d25 301 Pfam PF02682 Allophanate hydrolase subunit 1 12 229 1.0E-51 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 SUPERFAMILY SSF50156 197 297 1.84E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 Gene3D G3DSA:2.40.10.10 109 213 5.9E-34 T 09-03-2017 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 Gene3D G3DSA:2.30.42.10 214 302 1.3E-18 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 Pfam PF13365 Trypsin-like peptidase domain 38 177 4.2E-28 T 09-03-2017 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 SMART SM00228 212 294 7.8E-9 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 Pfam PF13180 PDZ domain 233 296 1.0E-11 T 09-03-2017 IPR001478 PDZ domain GO:0005515 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 108 132 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 148 165 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 47 59 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 252 264 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 68 88 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 PRINTS PR00834 HtrA/DegQ protease family signature 170 187 3.9E-46 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 SUPERFAMILY SSF50494 11 219 2.1E-45 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS04980 6ee3a87231bd6871381947689645b8fd 307 Gene3D G3DSA:2.40.10.10 33 108 1.6E-19 T 09-03-2017 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 SMART SM00418 35 116 1.3E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 Gene3D G3DSA:1.10.10.10 14 115 7.4E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 61 79 - T 09-03-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 2.1E-21 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.1E-21 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 2.1E-21 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.1E-21 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 SUPERFAMILY SSF46785 23 114 9.26E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17700 b7685347725c48a10aa6e89b5a40b813 117 Pfam PF01022 Bacterial regulatory protein, arsR family 42 89 1.5E-14 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS17130 3adb4ac735c66a33318dd4498b12d28c 301 Gene3D G3DSA:1.10.600.10 14 294 2.7E-36 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS17130 3adb4ac735c66a33318dd4498b12d28c 301 SUPERFAMILY SSF48576 18 296 5.61E-46 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS17130 3adb4ac735c66a33318dd4498b12d28c 301 Pfam PF00494 Squalene/phytoene synthase 26 266 3.2E-29 T 09-03-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 6 19 1.2E-10 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 38 51 1.2E-10 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 23 37 1.2E-10 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 Gene3D G3DSA:2.40.50.100 3 76 7.7E-23 T 09-03-2017 ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 SUPERFAMILY SSF51230 3 76 3.8E-19 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS13740 d64305c3b48060ac78562c5022fc4d1c 79 Pfam PF00364 Biotin-requiring enzyme 3 75 3.4E-15 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS05015 3279bbdfb061c9de5554b1a37d65235a 371 Gene3D G3DSA:3.40.50.300 118 292 6.2E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05015 3279bbdfb061c9de5554b1a37d65235a 371 Gene3D G3DSA:1.10.40.50 294 354 2.7E-9 T 09-03-2017 ARZXY2_RS05015 3279bbdfb061c9de5554b1a37d65235a 371 Pfam PF03193 Protein of unknown function, DUF258 100 292 3.3E-37 T 09-03-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 ARZXY2_RS05015 3279bbdfb061c9de5554b1a37d65235a 371 SUPERFAMILY SSF52540 118 309 7.39E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05015 3279bbdfb061c9de5554b1a37d65235a 371 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 360 25.553 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 5.1E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 SUPERFAMILY SSF48498 101 202 1.14E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 Pfam PF13977 Bacterial transcriptional repressor 103 204 2.1E-6 T 09-03-2017 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 Gene3D G3DSA:1.10.357.10 20 204 1.7E-37 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS07265 c75954c9e840367de0f62785ff7c51d1 213 SUPERFAMILY SSF46689 14 83 8.51E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 Gene3D G3DSA:1.10.10.10 8 70 1.1E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 Pfam PF01614 Bacterial transcriptional regulator 130 242 2.9E-10 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 SUPERFAMILY SSF55781 66 244 3.27E-34 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 SUPERFAMILY SSF46785 10 74 2.14E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 SMART SM00346 8 97 5.1E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 Pfam PF09339 IclR helix-turn-helix domain 11 58 2.7E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS19760 d7ed0e7001729cceb192fabf1cb4086d 246 Gene3D G3DSA:3.30.450.40 82 238 1.3E-33 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 SUPERFAMILY SSF52467 192 305 5.14E-68 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 SUPERFAMILY SSF52467 39 160 5.14E-68 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Pfam PF02146 Sir2 family 49 254 3.2E-35 T 09-03-2017 IPR003000 Sirtuin family GO:0070403 ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.40.50.1220 38 59 2.4E-36 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.40.50.1220 231 302 2.4E-36 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.40.50.1220 107 144 2.4E-36 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.30.1600.10 60 93 2.8E-14 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.30.1600.10 145 167 2.8E-14 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain ARZXY2_RS07360 f603cf11dba7fdcced49cd7641495ec7 318 Gene3D G3DSA:3.30.1600.10 201 225 2.8E-14 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 SUPERFAMILY SSF53720 15 499 6.02E-161 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 Gene3D G3DSA:3.40.605.10 19 271 7.9E-93 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 3.2E-162 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS02970 b1785d3428c0d13bdac923cacf99b9b7 507 Gene3D G3DSA:3.40.309.10 272 470 7.9E-58 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Pfam PF00270 DEAD/DEAH box helicase 42 97 7.5E-7 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SUPERFAMILY SSF52540 217 288 3.43E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SUPERFAMILY SSF52540 478 644 3.43E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SUPERFAMILY SSF52540 46 101 3.43E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SUPERFAMILY SSF52540 431 445 3.43E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Pfam PF13307 Helicase C-terminal domain 504 663 7.8E-32 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Gene3D G3DSA:3.40.50.300 35 130 4.6E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Gene3D G3DSA:3.40.50.300 228 296 4.6E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Gene3D G3DSA:3.40.50.300 433 442 4.6E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SMART SM00491 521 650 3.2E-40 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 Gene3D G3DSA:3.40.50.300 495 646 6.2E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11350 457d86e7cad99eb09cf6c30415994411 685 SMART SM00487 29 339 4.4E-5 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS17665 cdcd45315188beb674206cbaeafb5276 375 Pfam PF13515 Fusaric acid resistance protein-like 45 163 4.3E-10 T 09-03-2017 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 242 429 3.0E-61 T 09-03-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Gene3D G3DSA:1.10.730.10 636 777 6.9E-30 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 24 841 21.679 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Gene3D G3DSA:3.40.50.620 25 243 2.0E-142 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Gene3D G3DSA:3.40.50.620 451 635 2.0E-142 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 205 218 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 236 255 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 517 535 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 556 578 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 589 599 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 173 189 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 PRINTS PR00985 Leucyl-tRNA synthetase signature 147 164 4.1E-51 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 62 73 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 444 646 6.1E-16 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 SUPERFAMILY SSF50677 247 441 1.36E-48 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 SUPERFAMILY SSF52374 442 646 6.48E-138 T 09-03-2017 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 SUPERFAMILY SSF52374 23 247 6.48E-138 T 09-03-2017 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Gene3D G3DSA:3.90.740.10 244 450 3.7E-54 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 25 840 5.7E-286 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Pfam PF08264 Anticodon-binding domain of tRNA 680 803 8.0E-15 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 SUPERFAMILY SSF47323 656 840 3.55E-27 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS08220 063849f9291c9b1ca136c8d7494a6223 842 Pfam PF09334 tRNA synthetases class I (M) 61 202 2.5E-20 T 09-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.3E-28 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 Gene3D G3DSA:3.40.47.10 3 255 1.1E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 SUPERFAMILY SSF53901 213 410 1.57E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.5E-55 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 SMART SM00825 Beta-ketoacyl synthase 5 402 1.8E-12 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 PIRSF PIRSF000447 1 411 1.6E-140 T 09-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 Gene3D G3DSA:3.40.47.10 262 410 1.1E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS07320 30205476762b17faa027e6f035ecf623 411 SUPERFAMILY SSF53901 3 250 6.51E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 8.7E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 8.7E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 8.7E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.9E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.9E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.9E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.9E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.9E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 178 6.6E-4 T 09-03-2017 ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 Pfam PF00106 short chain dehydrogenase 5 188 2.6E-50 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 Gene3D G3DSA:3.40.50.720 3 236 8.4E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 SUPERFAMILY SSF51735 3 236 1.57E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01465 e1573eca7115c74f367c08033180da55 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS14230 f3448fe99db59f28b9eec1cb7a90176a 247 SUPERFAMILY SSF54001 136 236 1.37E-29 T 09-03-2017 ARZXY2_RS14230 f3448fe99db59f28b9eec1cb7a90176a 247 Gene3D G3DSA:3.90.1720.10 135 236 2.4E-28 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS14230 f3448fe99db59f28b9eec1cb7a90176a 247 Pfam PF00877 NlpC/P60 family 152 229 7.2E-20 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 SUPERFAMILY SSF53623 7 303 1.37E-88 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 445 2.0E-106 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 378 4.5E-10 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 Gene3D G3DSA:3.90.190.20 307 450 8.6E-35 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 Gene3D G3DSA:3.40.1190.10 13 304 9.9E-95 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 PIRSF PIRSF001563 2 452 4.8E-114 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 SUPERFAMILY SSF53244 306 445 3.66E-24 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS07640 87d2dcaf23ddbbb3a3c835d679507a47 453 Pfam PF08245 Mur ligase middle domain 49 279 2.8E-14 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 31 60 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 SUPERFAMILY SSF47005 143 184 6.93E-12 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 SUPERFAMILY SSF51230 4 99 3.8E-26 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Gene3D G3DSA:3.30.559.10 193 430 8.2E-82 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Pfam PF02817 e3 binding domain 147 181 5.0E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 202 428 5.1E-78 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 SUPERFAMILY SSF52777 192 430 4.89E-79 T 09-03-2017 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Gene3D G3DSA:2.40.50.100 3 98 1.4E-25 T 09-03-2017 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Gene3D G3DSA:4.10.320.10 143 190 7.1E-19 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS11720 c7c00bf5efcb8b6a1fb2ea2863cdfdc7 433 Pfam PF00364 Biotin-requiring enzyme 7 79 9.2E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 Gene3D G3DSA:3.40.800.10 17 319 7.8E-114 T 09-03-2017 IPR023696 Ureohydrolase domain ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 Pfam PF00491 Arginase family 41 313 7.7E-90 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 PRINTS PR00116 Arginase signature 128 143 3.4E-14 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 PRINTS PR00116 Arginase signature 242 271 3.4E-14 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 SUPERFAMILY SSF52768 21 318 9.18E-97 T 09-03-2017 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 TIGRFAM TIGR01230 agmatinase: agmatinase 38 314 3.6E-66 T 09-03-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 ProSitePatterns PS01053 Arginase family signature. 245 266 - T 09-03-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 ARZXY2_RS13985 db493b8e5efaa94236bf3f01dcd00e56 351 PIRSF PIRSF036979 21 321 1.3E-116 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 SUPERFAMILY SSF46689 13 85 1.24E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 Pfam PF01380 SIS domain 144 264 5.2E-17 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 SUPERFAMILY SSF53697 107 279 2.1E-15 T 09-03-2017 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 Gene3D G3DSA:3.40.50.10490 118 278 3.5E-13 T 09-03-2017 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 13 85 1.9E-8 T 09-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ARZXY2_RS16390 6db60925cba340b54366ec09131decf7 291 Gene3D G3DSA:1.10.10.10 13 86 5.0E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03225 ab0635bee5353b854ae3cf70430ca8b6 295 Pfam PF00005 ABC transporter 31 175 5.0E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS03225 ab0635bee5353b854ae3cf70430ca8b6 295 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS03225 ab0635bee5353b854ae3cf70430ca8b6 295 Gene3D G3DSA:3.40.50.300 3 227 1.8E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03225 ab0635bee5353b854ae3cf70430ca8b6 295 SMART SM00382 39 237 1.3E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS03225 ab0635bee5353b854ae3cf70430ca8b6 295 SUPERFAMILY SSF52540 6 228 9.56E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18310 6ab5250eb39db4f0e7468111e580bf0f 498 SUPERFAMILY SSF52091 408 488 2.35E-11 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS18310 6ab5250eb39db4f0e7468111e580bf0f 498 Gene3D G3DSA:3.30.750.24 408 487 1.1E-9 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS18310 6ab5250eb39db4f0e7468111e580bf0f 498 Pfam PF00916 Sulfate permease family 169 361 5.0E-24 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS18310 6ab5250eb39db4f0e7468111e580bf0f 498 Pfam PF00916 Sulfate permease family 24 149 1.8E-19 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS18310 6ab5250eb39db4f0e7468111e580bf0f 498 Pfam PF01740 STAS domain 410 490 9.1E-8 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 314 329 4.3E-10 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 157 171 4.3E-10 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 247 266 4.3E-10 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Gene3D G3DSA:3.40.120.10 248 325 2.7E-21 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 229 330 2.5E-25 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 SUPERFAMILY SSF55957 467 552 4.97E-15 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 57 179 4.0E-32 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Gene3D G3DSA:3.30.310.50 489 566 2.1E-19 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 158 167 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 SUPERFAMILY SSF53738 229 330 7.85E-23 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 344 459 4.3E-13 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Gene3D G3DSA:3.40.120.10 44 207 4.4E-50 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Gene3D G3DSA:3.40.120.10 326 466 9.3E-35 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 SUPERFAMILY SSF53738 47 254 1.81E-36 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 501 556 3.0E-8 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS12575 ad637a4692cb27b07afacc876b34f333 581 SUPERFAMILY SSF53738 322 465 2.28E-27 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 ProSitePatterns PS00438 Catalase proximal active site signature. 42 58 - T 09-03-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 Pfam PF06628 Catalase-related immune-responsive 416 478 5.1E-18 T 09-03-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 Gene3D G3DSA:2.40.180.10 4 355 3.6E-175 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 SUPERFAMILY SSF56634 4 482 1.83E-201 T 09-03-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PIRSF PIRSF038928 1 484 2.0E-227 T 09-03-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 Pfam PF00199 Catalase 6 385 9.5E-187 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 19 42 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 286 313 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 121 139 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 81 99 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 318 344 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 PRINTS PR00067 Catalase signature 102 119 4.0E-67 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 331 339 - T 09-03-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS02990 36719da28a02d96eb7fb40af5465581d 493 SMART SM01060 6 389 1.6E-278 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 PIRSF PIRSF000521 7 437 1.5E-36 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 Gene3D G3DSA:3.90.1150.10 314 437 5.5E-39 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 Pfam PF00202 Aminotransferase class-III 17 434 8.3E-105 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 Gene3D G3DSA:3.40.640.10 52 313 4.0E-80 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS07145 f00e4c78f804fe9cbbee20664d3f4324 460 SUPERFAMILY SSF53383 14 435 2.26E-117 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS19265 7467088b4b853214ecefe314c277311c 162 Gene3D G3DSA:3.40.50.880 21 160 1.3E-42 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS19265 7467088b4b853214ecefe314c277311c 162 Pfam PF01965 DJ-1/PfpI family 19 158 2.8E-42 T 09-03-2017 IPR002818 DJ-1/PfpI ARZXY2_RS19265 7467088b4b853214ecefe314c277311c 162 SUPERFAMILY SSF52317 22 161 9.17E-41 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS19265 7467088b4b853214ecefe314c277311c 162 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 22 161 1.8E-46 T 09-03-2017 IPR006286 Peptidase C56, PfpI ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 Gene3D G3DSA:3.30.428.10 72 205 8.3E-37 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 SUPERFAMILY SSF54197 48 206 2.84E-46 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 226 368 4.7E-16 T 09-03-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 PIRSF PIRSF000808 43 373 1.0E-102 T 09-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 52 370 3.4E-40 T 09-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 SUPERFAMILY SSF54197 233 370 1.87E-34 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 49 205 2.3E-33 T 09-03-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 181 198 - T 09-03-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 ARZXY2_RS13040 c684201d3479d345654f88236ca94c76 385 Gene3D G3DSA:3.30.428.10 216 370 7.8E-45 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS19530 e7a01f7ce4b51dbd36716488f99f9609 84 Pfam PF14081 Domain of unknown function (DUF4262) 10 67 3.9E-7 T 09-03-2017 IPR025358 Protein of unknown function DUF4262 ARZXY2_RS01540 e5d052e7e61f405cf146f14d745de49f 194 SUPERFAMILY SSF109854 2 156 9.16E-39 T 09-03-2017 ARZXY2_RS01540 e5d052e7e61f405cf146f14d745de49f 194 Gene3D G3DSA:1.20.120.450 2 160 3.1E-34 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase ARZXY2_RS01540 e5d052e7e61f405cf146f14d745de49f 194 Pfam PF04978 Protein of unknown function (DUF664) 6 157 1.2E-47 T 09-03-2017 IPR007061 Protein of unknown function DUF664 ARZXY2_RS06135 8da864cf5366bb6c116709fb46092a2f 141 SUPERFAMILY SSF50475 9 132 2.8E-25 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS06135 8da864cf5366bb6c116709fb46092a2f 141 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 130 1.0E-23 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS06135 8da864cf5366bb6c116709fb46092a2f 141 Gene3D G3DSA:2.30.110.10 4 140 1.9E-44 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS07245 d6cc611237ba86792ce6cff833b33b63 131 Gene3D G3DSA:2.60.120.10 10 118 2.0E-7 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS07245 d6cc611237ba86792ce6cff833b33b63 131 SUPERFAMILY SSF51182 65 130 6.82E-8 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS12425 f4e8068928da8b9a4ef233ce1ec5bd66 298 SMART SM00331 27 254 1.1E-24 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS12425 f4e8068928da8b9a4ef233ce1ec5bd66 298 SUPERFAMILY SSF81606 21 254 1.1E-55 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS12425 f4e8068928da8b9a4ef233ce1ec5bd66 298 Pfam PF13672 Protein phosphatase 2C 32 224 1.5E-11 T 09-03-2017 ARZXY2_RS12425 f4e8068928da8b9a4ef233ce1ec5bd66 298 SMART SM00332 12 252 9.0E-21 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS12425 f4e8068928da8b9a4ef233ce1ec5bd66 298 Gene3D G3DSA:3.60.40.10 21 253 2.7E-64 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 Gene3D G3DSA:3.30.360.10 136 333 1.6E-46 T 09-03-2017 ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 122 1.5E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 5 329 7.6E-108 T 09-03-2017 IPR030827 Inositol 2-dehydrogenase ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 Gene3D G3DSA:3.40.50.720 2 135 1.8E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 SUPERFAMILY SSF55347 130 278 3.27E-24 T 09-03-2017 ARZXY2_RS09705 f2547062e8d13db8de56fd005792cda4 336 SUPERFAMILY SSF51735 3 146 1.47E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16585 c521932cb639651149533c080612a96a 339 SUPERFAMILY SSF161098 31 326 1.44E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16585 c521932cb639651149533c080612a96a 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 324 3.4E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16585 c521932cb639651149533c080612a96a 339 Gene3D G3DSA:1.10.3720.10 27 321 1.1E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 Gene3D G3DSA:1.10.10.60 550 588 5.5E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 SUPERFAMILY SSF52540 338 536 2.2E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 Pfam PF02954 Bacterial regulatory protein, Fis family 551 589 2.1E-10 T 09-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 SUPERFAMILY SSF46689 549 589 6.57E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 Gene3D G3DSA:3.40.50.300 333 387 8.2E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 Gene3D G3DSA:1.10.8.60 472 539 5.6E-10 T 09-03-2017 ARZXY2_RS09775 a881fa43e9990d446697b450ae8458a9 598 Pfam PF14532 Sigma-54 interaction domain 341 450 4.6E-6 T 09-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 ARZXY2_RS16505 d4e47439127e617241d4458a38687430 228 Gene3D G3DSA:2.30.180.10 98 226 4.1E-25 T 09-03-2017 IPR000782 FAS1 domain ARZXY2_RS16505 d4e47439127e617241d4458a38687430 228 Pfam PF02469 Fasciclin domain 109 227 2.5E-26 T 09-03-2017 IPR000782 FAS1 domain ARZXY2_RS16505 d4e47439127e617241d4458a38687430 228 SUPERFAMILY SSF82153 72 227 1.83E-34 T 09-03-2017 IPR000782 FAS1 domain ARZXY2_RS16505 d4e47439127e617241d4458a38687430 228 SMART SM00554 133 228 9.0E-27 T 09-03-2017 IPR000782 FAS1 domain ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 23 432 1.4E-105 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 PIRSF PIRSF000337 11 446 4.3E-115 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 Gene3D G3DSA:3.20.20.30 351 438 7.5E-101 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 Gene3D G3DSA:3.20.20.30 8 299 7.5E-101 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 Pfam PF00296 Luciferase-like monooxygenase 14 388 1.4E-49 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00095 9dd3128673b642a0637a73c6b7813c14 447 SUPERFAMILY SSF51679 10 438 3.27E-97 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 SMART SM00487 34 238 8.6E-47 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 Gene3D G3DSA:3.40.50.300 229 379 3.0E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 Gene3D G3DSA:3.40.50.300 11 228 6.3E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 SMART SM00490 273 354 5.8E-27 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 SUPERFAMILY SSF52540 91 372 2.38E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 Pfam PF00270 DEAD/DEAH box helicase 39 212 5.8E-42 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS01010 0adc300cd2a86dd875faa8456c8bfd1c 590 Pfam PF00271 Helicase conserved C-terminal domain 254 354 1.7E-22 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 SUPERFAMILY SSF51735 8 232 3.36E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.2E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 Gene3D G3DSA:3.40.50.720 8 230 1.7E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 Pfam PF00106 short chain dehydrogenase 8 183 7.4E-48 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 0.0076 T 09-03-2017 ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 8.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 8.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19965 c0e16ce99c743816fa9764146b88c090 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 8.8E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01195 6b486c8e2a6066cd63674f6626901db8 110 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 3.9E-24 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 ARZXY2_RS01195 6b486c8e2a6066cd63674f6626901db8 110 SUPERFAMILY SSF52091 1 107 3.92E-27 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS01195 6b486c8e2a6066cd63674f6626901db8 110 Pfam PF13466 STAS domain 18 94 7.2E-15 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS01195 6b486c8e2a6066cd63674f6626901db8 110 Gene3D G3DSA:3.30.750.24 1 107 5.2E-36 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS00860 84f4001dc677a58827f603933568e476 129 SUPERFAMILY SSF53613 6 109 2.65E-17 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS00860 84f4001dc677a58827f603933568e476 129 Gene3D G3DSA:3.40.1190.20 3 108 6.7E-23 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS00860 84f4001dc677a58827f603933568e476 129 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 51 64 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS00860 84f4001dc677a58827f603933568e476 129 Pfam PF00294 pfkB family carbohydrate kinase 3 105 1.6E-13 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 Gene3D G3DSA:3.30.470.10 20 186 2.1E-69 T 09-03-2017 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 ProSitePatterns PS00770 Aminotransferases class-IV signature. 245 275 - T 09-03-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 Pfam PF01063 Amino-transferase class IV 82 323 4.3E-35 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 Gene3D G3DSA:3.20.10.10 187 355 2.1E-61 T 09-03-2017 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 56 368 2.7E-133 T 09-03-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 PIRSF PIRSF006468 8 370 5.3E-129 T 09-03-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 ARZXY2_RS05685 4c3bb95dad9361a555bbc2fcdb51e4f0 370 SUPERFAMILY SSF56752 9 366 6.93E-112 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 Hamap MF_01227 CTP synthase [pyrG]. 26 564 49.831 T 09-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 Gene3D G3DSA:3.40.50.880 313 564 1.5E-87 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 TIGRFAM TIGR00337 PyrG: CTP synthase 25 559 7.2E-231 T 09-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 SUPERFAMILY SSF52317 314 565 3.95E-74 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 Pfam PF00117 Glutamine amidotransferase class-I 327 559 2.7E-49 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 Gene3D G3DSA:3.40.50.300 23 310 4.8E-130 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 SUPERFAMILY SSF52540 26 292 6.51E-116 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11115 28c4cf84e6cfbee5ebcb4698ce74d559 581 Pfam PF06418 CTP synthase N-terminus 27 292 3.0E-121 T 09-03-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 ARZXY2_RS12220 f0a8ab82102b41bcbf2c6c568fed5c94 271 SUPERFAMILY SSF52266 18 206 9.49E-40 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS12220 f0a8ab82102b41bcbf2c6c568fed5c94 271 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 24 196 1.9E-24 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS12220 f0a8ab82102b41bcbf2c6c568fed5c94 271 Gene3D G3DSA:3.40.50.1110 18 208 1.4E-39 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS18070 0a2e6c5bf752458920aa331299d0beaf 344 SUPERFAMILY SSF51735 1 327 2.41E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18070 0a2e6c5bf752458920aa331299d0beaf 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 245 1.3E-22 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS18070 0a2e6c5bf752458920aa331299d0beaf 344 Gene3D G3DSA:3.90.25.10 225 327 2.8E-7 T 09-03-2017 ARZXY2_RS18070 0a2e6c5bf752458920aa331299d0beaf 344 Gene3D G3DSA:3.40.50.720 1 224 9.1E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 Pfam PF02626 Allophanate hydrolase subunit 2 259 536 4.3E-76 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 SMART SM00797 258 545 1.3E-88 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 Pfam PF02682 Allophanate hydrolase subunit 1 16 202 2.7E-57 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 SUPERFAMILY SSF50891 93 215 8.34E-40 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 SMART SM00796 14 203 5.8E-77 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 Gene3D G3DSA:2.40.100.10 428 538 1.0E-11 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 Gene3D G3DSA:2.40.100.10 92 216 4.0E-47 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS18325 fd483b32f29c4f62477c4b7600f0a054 549 SUPERFAMILY SSF50891 428 538 1.37E-16 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 SMART SM01012 142 197 2.2E-23 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 PIRSF PIRSF036382 6 201 1.4E-69 T 09-03-2017 IPR008327 Signal transduction response regulator, antiterminator ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 SUPERFAMILY SSF52172 15 197 1.85E-54 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 Gene3D G3DSA:1.10.10.10 145 200 1.4E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 Pfam PF00072 Response regulator receiver domain 17 126 5.1E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 Gene3D G3DSA:3.40.50.2300 12 137 3.2E-38 T 09-03-2017 ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 Pfam PF03861 ANTAR domain 145 197 1.8E-19 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS10235 9881bd207318b3325bce69899adeae60 201 SMART SM00448 15 126 4.4E-36 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 SUPERFAMILY SSF46785 16 86 1.02E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 SUPERFAMILY SSF48008 89 225 8.89E-32 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 2.1E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 SMART SM00895 93 220 7.8E-25 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 SMART SM00345 24 82 1.2E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 Gene3D G3DSA:1.20.120.530 87 227 9.4E-33 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 Gene3D G3DSA:1.10.10.10 15 84 1.7E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13825 593abe6f0e90a5f07fc747cfe814eb64 232 Pfam PF07729 FCD domain 93 219 7.7E-30 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 SUPERFAMILY SSF55424 368 479 1.19E-25 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 Gene3D G3DSA:3.30.390.30 365 481 1.3E-25 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 Gene3D G3DSA:3.50.50.60 8 152 8.2E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.6E-19 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 323 1.6E-19 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.6E-19 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 1.6E-19 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.6E-19 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 SUPERFAMILY SSF51905 3 346 3.09E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 325 3.1E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 Gene3D G3DSA:3.50.50.60 153 343 2.4E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 370 475 2.9E-20 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 316 323 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 446 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 387 5.5E-48 T 09-03-2017 ARZXY2_RS15170 d1ed9f128a6adcf7eb27050fad166336 484 PIRSF PIRSF000350 1 479 2.4E-72 T 09-03-2017 ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 Pfam PF13673 Acetyltransferase (GNAT) domain 44 133 2.3E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 Gene3D G3DSA:3.40.50.300 157 355 3.2E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 326 4.9E-24 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 Gene3D G3DSA:3.40.630.30 2 130 4.2E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 Gene3D G3DSA:1.10.8.60 356 421 7.0E-4 T 09-03-2017 ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 SUPERFAMILY SSF52540 158 380 2.72E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 SUPERFAMILY SSF55729 1 143 1.44E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 SMART SM00382 194 329 5.3E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS20435 33b8dbd9dafc02e4d93b2cfc42135f88 439 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 ARZXY2_RS13910 03b120b4f6628167f131a6097e104bd3 491 SUPERFAMILY SSF53720 12 490 1.1E-139 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS13910 03b120b4f6628167f131a6097e104bd3 491 Gene3D G3DSA:3.40.605.10 17 272 9.1E-82 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS13910 03b120b4f6628167f131a6097e104bd3 491 Pfam PF00171 Aldehyde dehydrogenase family 33 487 8.3E-142 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS13910 03b120b4f6628167f131a6097e104bd3 491 Gene3D G3DSA:3.40.309.10 273 460 1.7E-52 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS13910 03b120b4f6628167f131a6097e104bd3 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 287 298 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Gene3D G3DSA:3.40.50.1220 190 343 6.0E-35 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 174 1.6E-37 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 SUPERFAMILY SSF52518 6 184 5.4E-40 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Gene3D G3DSA:3.40.50.970 4 181 8.2E-48 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 SUPERFAMILY SSF52518 362 558 1.29E-59 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Gene3D G3DSA:3.40.50.970 358 560 1.4E-58 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 322 2.6E-25 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 530 6.3E-38 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS09355 ff4bc2a2b9c770fecde15c88b93c0dfd 582 SUPERFAMILY SSF52467 188 347 1.13E-35 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 Pfam PF07729 FCD domain 85 212 2.3E-17 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 SMART SM00345 14 72 3.7E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 SMART SM00895 82 213 2.0E-8 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 Gene3D G3DSA:1.10.10.10 3 73 4.6E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 SUPERFAMILY SSF46785 4 80 5.13E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 5.1E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 SUPERFAMILY SSF48008 78 219 4.97E-15 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS19140 de3125d0df8c982913f3c051c2c6c970 234 Gene3D G3DSA:1.20.120.530 76 221 2.1E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 Pfam PF02803 Thiolase, C-terminal domain 287 392 4.8E-9 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 Pfam PF00108 Thiolase, N-terminal domain 20 130 5.1E-14 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 Gene3D G3DSA:3.40.47.10 19 120 5.6E-28 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 Gene3D G3DSA:3.40.47.10 221 250 5.6E-28 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 Gene3D G3DSA:3.40.47.10 278 405 8.8E-20 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 PIRSF PIRSF000429 6 406 7.1E-52 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 SUPERFAMILY SSF53901 209 384 2.8E-39 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS16530 2b0721583a06f192b2f20fed0abb3dcf 409 SUPERFAMILY SSF53901 8 127 2.8E-39 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS02935 1e219841c27dcabad909f42a0ec47b37 423 SUPERFAMILY SSF103473 29 411 3.66E-31 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS02935 1e219841c27dcabad909f42a0ec47b37 423 Gene3D G3DSA:1.20.1250.20 238 413 2.6E-6 T 09-03-2017 ARZXY2_RS02935 1e219841c27dcabad909f42a0ec47b37 423 Gene3D G3DSA:1.20.1250.20 57 215 5.2E-10 T 09-03-2017 ARZXY2_RS02935 1e219841c27dcabad909f42a0ec47b37 423 Pfam PF07690 Major Facilitator Superfamily 53 373 5.0E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS20285 c7841e92ce2eb04ac5532918a4a48e45 272 SUPERFAMILY SSF69318 12 249 1.44E-25 T 09-03-2017 ARZXY2_RS20285 c7841e92ce2eb04ac5532918a4a48e45 272 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 61 121 1.4E-7 T 09-03-2017 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 Gene3D G3DSA:3.10.290.10 332 434 2.4E-32 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 SUPERFAMILY SSF52374 18 338 3.03E-96 T 09-03-2017 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 SUPERFAMILY SSF55174 341 433 4.42E-18 T 09-03-2017 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 18 434 5.8E-114 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 Gene3D G3DSA:1.10.240.10 248 331 7.5E-39 T 09-03-2017 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 59 81 2.0E-25 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 198 220 2.0E-25 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 177 192 2.0E-25 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 231 243 2.0E-25 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 55 65 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 SMART SM00363 369 430 0.0058 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 Gene3D G3DSA:3.40.50.620 6 247 3.0E-94 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 17 434 43.228 T 09-03-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 ARZXY2_RS11170 d76cd16ebe2722ca6e58022d67df5a2a 436 Pfam PF00579 tRNA synthetases class I (W and Y) 45 338 2.1E-76 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 Gene3D G3DSA:3.30.450.40 83 260 2.7E-38 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 SUPERFAMILY SSF55781 79 259 4.58E-39 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 SMART SM00346 14 104 1.2E-18 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 SUPERFAMILY SSF46785 15 87 1.17E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 Pfam PF09339 IclR helix-turn-helix domain 17 65 1.0E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 Gene3D G3DSA:1.10.10.10 12 82 2.4E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16515 d21ba36bb96f742b8f9ef69bc9926599 265 Pfam PF01614 Bacterial transcriptional regulator 135 253 1.1E-9 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS19510 ba88181c500933bda78cded28e4b941a 972 Gene3D G3DSA:2.60.120.200 785 939 8.3E-8 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS19510 ba88181c500933bda78cded28e4b941a 972 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 795 948 7.4E-11 T 09-03-2017 ARZXY2_RS19510 ba88181c500933bda78cded28e4b941a 972 SMART SM00560 810 945 0.0099 T 09-03-2017 IPR006558 LamG-like jellyroll fold ARZXY2_RS19510 ba88181c500933bda78cded28e4b941a 972 SUPERFAMILY SSF49899 794 953 1.28E-9 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS17035 223fbab573ef3e3f7c8b52f6ccf29d17 379 Gene3D G3DSA:2.60.120.10 58 198 3.8E-35 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS17035 223fbab573ef3e3f7c8b52f6ccf29d17 379 Gene3D G3DSA:2.60.120.10 234 371 5.6E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS17035 223fbab573ef3e3f7c8b52f6ccf29d17 379 Pfam PF07883 Cupin domain 116 181 1.3E-18 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS17035 223fbab573ef3e3f7c8b52f6ccf29d17 379 SUPERFAMILY SSF51182 27 371 1.03E-105 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 2.1E-127 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 SUPERFAMILY SSF56014 277 361 1.13E-11 T 09-03-2017 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 Pfam PF04551 GcpE protein 22 362 8.6E-132 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 Gene3D G3DSA:3.20.20.70 53 173 4.4E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.469 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 PIRSF PIRSF004640 13 374 2.6E-143 T 09-03-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 ARZXY2_RS11610 c51849bd443201b7c7a0d0b614750724 388 SUPERFAMILY SSF51717 48 219 7.22E-9 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 Gene3D G3DSA:3.40.1190.20 43 315 1.6E-59 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 SUPERFAMILY SSF53613 9 313 1.25E-56 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 Pfam PF00294 pfkB family carbohydrate kinase 18 302 4.1E-38 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 Gene3D G3DSA:2.20.150.10 16 42 7.2E-4 T 09-03-2017 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 PIRSF PIRSF000535 6 318 1.1E-63 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ARZXY2_RS12270 cb3c072827d3b79fc3977fddc17edee4 322 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 9 314 1.5E-71 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 4.0E-73 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.9E-46 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 538 555 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Gene3D G3DSA:3.30.1490.20 129 202 3.8E-25 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Gene3D G3DSA:3.40.50.20 1 128 2.6E-49 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Pfam PF02785 Biotin carboxylase C-terminal domain 334 442 1.0E-32 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 SUPERFAMILY SSF56059 116 322 7.78E-61 T 09-03-2017 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 SMART SM00878 334 441 1.7E-47 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Pfam PF00364 Biotin-requiring enzyme 516 580 3.6E-16 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Gene3D G3DSA:3.30.470.20 204 445 1.5E-91 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 SUPERFAMILY SSF51230 510 580 1.31E-19 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 SUPERFAMILY SSF51246 328 445 1.46E-33 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 Gene3D G3DSA:2.40.50.100 512 581 2.1E-23 T 09-03-2017 ARZXY2_RS16965 c31aa38a2c4479724a9f68d8e2edd8a3 587 SUPERFAMILY SSF52440 1 113 4.39E-48 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS01605 7a1162d7c69cee9f86338f05c3d1e1c5 164 SUPERFAMILY SSF53927 5 137 2.17E-39 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS01605 7a1162d7c69cee9f86338f05c3d1e1c5 164 Gene3D G3DSA:3.40.140.10 4 137 4.4E-42 T 09-03-2017 ARZXY2_RS01605 7a1162d7c69cee9f86338f05c3d1e1c5 164 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 104 2.4E-22 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 SUPERFAMILY SSF46785 9 97 5.82E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 Gene3D G3DSA:1.10.10.10 14 100 8.2E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 52 1.5E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.5E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.5E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.5E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 Pfam PF12840 Helix-turn-helix domain 19 75 3.2E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12600 c07acf45c65d94a01f1dd557f5c45c04 125 SMART SM00418 19 98 5.5E-19 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 Gene3D G3DSA:3.40.50.720 9 249 7.7E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.4E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.4E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.4E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 SUPERFAMILY SSF51735 7 250 1.26E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 Pfam PF00106 short chain dehydrogenase 12 198 1.1E-45 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.0E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.0E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.0E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS01655 20e2c3c3e6ae93c3d14f58fb9aba1b30 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.0E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 SMART SM01012 175 230 1.5E-19 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 Gene3D G3DSA:1.10.10.10 178 232 7.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 SUPERFAMILY SSF52172 151 230 2.63E-9 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 SUPERFAMILY SSF55781 31 170 1.22E-15 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 Gene3D G3DSA:3.30.450.40 11 166 2.4E-16 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 PIRSF PIRSF036625 1 242 3.8E-45 T 09-03-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 Pfam PF13185 GAF domain 62 147 4.5E-8 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS17160 a02ebf5f70a15afaed71e18f80e2242f 246 Pfam PF03861 ANTAR domain 178 230 1.5E-17 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 Pfam PF13558 Putative exonuclease SbcCD, C subunit 924 990 5.5E-14 T 09-03-2017 ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 Gene3D G3DSA:3.40.50.300 613 614 2.3E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 Gene3D G3DSA:3.40.50.300 889 1030 2.3E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 Gene3D G3DSA:3.40.50.300 2 179 2.3E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 Pfam PF13476 AAA domain 5 192 2.2E-26 T 09-03-2017 ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 SUPERFAMILY SSF52540 2 223 2.42E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 SUPERFAMILY SSF52540 684 698 2.42E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05450 7733ad7a47853a8895f8ce5bd1528962 1035 SUPERFAMILY SSF52540 878 1025 2.42E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.945 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 Pfam PF00444 Ribosomal protein L36 1 37 1.5E-19 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 SUPERFAMILY SSF57840 1 37 1.57E-17 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 09-03-2017 ARZXY2_RS03655 8891d7bbd612ee67cfc204f650d7fa0a 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.0E-22 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 Pfam PF02545 Maf-like protein 3 205 2.4E-45 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 Hamap MF_00528 Septum formation protein Maf [maf]. 3 210 26.741 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 203 9.7E-45 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 PIRSF PIRSF006305 1 211 1.6E-42 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 Gene3D G3DSA:3.90.950.10 2 208 1.5E-59 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like ARZXY2_RS12520 ff9ad6b92f18cab1482297ddd41fca50 223 SUPERFAMILY SSF52972 2 204 2.68E-48 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 Pfam PF00582 Universal stress protein family 9 141 1.1E-29 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 SUPERFAMILY SSF52402 9 143 1.09E-35 T 09-03-2017 ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 Gene3D G3DSA:3.40.50.620 8 143 1.2E-38 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 PRINTS PR01438 Universal stress protein signature 119 141 1.2E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 PRINTS PR01438 Universal stress protein signature 6 24 1.2E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS06040 b70330a5f7f5f83839a7f3437449d3a5 148 PRINTS PR01438 Universal stress protein signature 101 113 1.2E-18 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09360 3d0b28405185d0d39ff37098421a991c 68 Pfam PF11160 Protein of unknown function (DUF2945) 6 65 4.3E-26 T 09-03-2017 IPR021331 Protein of unknown function DUF2945 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 44 68 9.4E-8 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 155 9.4E-8 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 331 355 9.4E-8 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 165 189 9.4E-8 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 Gene3D G3DSA:1.20.1250.20 42 215 2.4E-22 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 Gene3D G3DSA:1.20.1250.20 295 484 8.8E-16 T 09-03-2017 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 SUPERFAMILY SSF103473 32 222 1.83E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 SUPERFAMILY SSF103473 277 482 1.83E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 40 445 3.0E-94 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ARZXY2_RS17945 18c7b395a54fa2bfcf7912adcbc3fe36 492 Pfam PF07690 Major Facilitator Superfamily 45 438 4.2E-40 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS03115 e1a12655eb260cda51b79d6ddd75c10c 308 Gene3D G3DSA:1.10.3720.10 30 296 3.4E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03115 e1a12655eb260cda51b79d6ddd75c10c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 293 3.1E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03115 e1a12655eb260cda51b79d6ddd75c10c 308 SUPERFAMILY SSF161098 31 308 9.29E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 Pfam PF00176 SNF2 family N-terminal domain 250 402 6.6E-8 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 SMART SM00487 13 316 4.4E-8 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 Pfam PF00271 Helicase conserved C-terminal domain 454 557 1.8E-5 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 SUPERFAMILY SSF52540 443 595 3.48E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 SUPERFAMILY SSF52540 248 304 3.48E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 Gene3D G3DSA:3.40.50.300 15 127 2.4E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 Gene3D G3DSA:3.40.50.300 242 301 2.4E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 SUPERFAMILY SSF52540 9 129 1.97E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 SUPERFAMILY SSF52540 242 328 1.97E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06425 8407311e5e56b49b06405ab4f8d453c6 622 Gene3D G3DSA:3.40.50.300 446 565 1.8E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 SUPERFAMILY SSF51338 25 86 5.4E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 Gene3D G3DSA:3.20.20.140 86 414 8.7E-81 T 09-03-2017 ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 SUPERFAMILY SSF51338 378 471 4.09E-23 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 Gene3D G3DSA:2.30.40.10 4 85 3.5E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 Pfam PF01979 Amidohydrolase family 75 446 3.2E-64 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS19335 3e2fba4571b75a3dce29c3cc68894e91 490 SUPERFAMILY SSF51556 77 395 1.64E-76 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 PRINTS PR00419 Adrenodoxin reductase family signature 45 58 1.0E-6 T 09-03-2017 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 PRINTS PR00419 Adrenodoxin reductase family signature 22 44 1.0E-6 T 09-03-2017 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 Pfam PF12831 FAD dependent oxidoreductase 357 426 1.1E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 Pfam PF12831 FAD dependent oxidoreductase 22 355 1.6E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 SUPERFAMILY SSF51905 21 105 7.02E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 SUPERFAMILY SSF51905 353 408 7.02E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 SUPERFAMILY SSF51905 133 214 7.02E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 Gene3D G3DSA:3.50.50.60 357 426 8.4E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 Gene3D G3DSA:3.50.50.60 21 196 8.4E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13885 dacd80b7b29305dd1f57ec84dba865cc 454 Gene3D G3DSA:3.50.50.60 252 295 8.4E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 Gene3D G3DSA:1.20.1250.20 22 226 5.7E-25 T 09-03-2017 ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 Gene3D G3DSA:1.20.1250.20 249 422 1.0E-19 T 09-03-2017 ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 Pfam PF07690 Major Facilitator Superfamily 31 377 3.9E-30 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 SUPERFAMILY SSF103473 21 423 3.01E-63 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00845 a226fe58d56f454ee5979b02e91be49d 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 300 316 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS22170 6b3e83a7520ead3fef7d7be4dc67981a 72 Pfam PF00581 Rhodanese-like domain 5 71 6.5E-9 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS22170 6b3e83a7520ead3fef7d7be4dc67981a 72 Gene3D G3DSA:3.40.250.10 1 71 1.6E-18 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS22170 6b3e83a7520ead3fef7d7be4dc67981a 72 SUPERFAMILY SSF52821 2 71 2.23E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS08980 a2500b5aeab1c3a00eab07da7436513f 110 Pfam PF01883 Domain of unknown function DUF59 12 72 2.5E-16 T 09-03-2017 IPR002744 Domain of unknown function DUF59 ARZXY2_RS08980 a2500b5aeab1c3a00eab07da7436513f 110 SUPERFAMILY SSF117916 11 104 2.13E-24 T 09-03-2017 ARZXY2_RS03045 f05bafc5d63d79513549650ba664c21b 266 Pfam PF12679 ABC-2 family transporter protein 7 264 1.2E-14 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 ARZXY2_RS03400 4e595d14f5173935f3b607529fd33228 93 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 31 86 2.3E-18 T 09-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 ARZXY2_RS03400 4e595d14f5173935f3b607529fd33228 93 Hamap MF_00422 Protein translocase subunit SecE [secE]. 28 83 12.766 T 09-03-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03400 4e595d14f5173935f3b607529fd33228 93 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 33 84 1.2E-19 T 09-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 ARZXY2_RS03400 4e595d14f5173935f3b607529fd33228 93 Gene3D G3DSA:1.20.5.1030 27 85 3.0E-21 T 09-03-2017 ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Pfam PF07731 Multicopper oxidase 395 509 2.2E-28 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Pfam PF00394 Multicopper oxidase 187 336 5.8E-15 T 09-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 SUPERFAMILY SSF49503 182 340 4.3E-21 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Gene3D G3DSA:2.60.40.420 182 380 1.8E-33 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Pfam PF07732 Multicopper oxidase 73 178 1.7E-33 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 ProSitePatterns PS00080 Multicopper oxidases signature 2. 494 505 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Gene3D G3DSA:2.60.40.420 56 179 5.8E-28 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 SUPERFAMILY SSF49503 52 195 7.34E-33 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 Gene3D G3DSA:2.60.40.420 381 511 2.6E-41 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06055 55b48042446f2a1ae335d703cbc3ad67 513 SUPERFAMILY SSF49503 392 509 2.17E-34 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Gene3D G3DSA:3.40.630.10 369 433 1.4E-58 T 09-03-2017 ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Gene3D G3DSA:3.40.630.10 7 206 1.4E-58 T 09-03-2017 ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Pfam PF01546 Peptidase family M20/M25/M40 79 432 4.9E-33 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 SUPERFAMILY SSF53187 7 188 9.71E-54 T 09-03-2017 ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 SUPERFAMILY SSF53187 344 434 9.71E-54 T 09-03-2017 ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Gene3D G3DSA:3.30.70.360 207 246 1.5E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Gene3D G3DSA:3.30.70.360 284 330 1.5E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 Pfam PF07687 Peptidase dimerisation domain 194 328 2.2E-14 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 SUPERFAMILY SSF55031 283 335 8.52E-11 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08805 676ff9a3e82a652d48603d8d56bccfb4 434 SUPERFAMILY SSF55031 197 239 8.52E-11 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS02255 7d5faf3689679594c57879fb1bc22a25 486 Pfam PF00324 Amino acid permease 35 471 3.8E-88 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS02255 7d5faf3689679594c57879fb1bc22a25 486 PIRSF PIRSF006060 15 486 6.4E-63 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS08225 48f3cdd86e3c2bb27cd3fdadb0f0782e 327 Pfam PF02645 Uncharacterised protein, DegV family COG1307 39 319 2.0E-70 T 09-03-2017 IPR003797 DegV ARZXY2_RS08225 48f3cdd86e3c2bb27cd3fdadb0f0782e 327 Gene3D G3DSA:3.40.50.10170 39 187 1.9E-40 T 09-03-2017 ARZXY2_RS08225 48f3cdd86e3c2bb27cd3fdadb0f0782e 327 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 40 319 1.7E-78 T 09-03-2017 IPR003797 DegV ARZXY2_RS08225 48f3cdd86e3c2bb27cd3fdadb0f0782e 327 SUPERFAMILY SSF82549 38 319 2.04E-68 T 09-03-2017 ARZXY2_RS08225 48f3cdd86e3c2bb27cd3fdadb0f0782e 327 Gene3D G3DSA:3.30.1180.10 191 319 3.1E-37 T 09-03-2017 ARZXY2_RS13945 c1a20e6b33573617c6aa3edd52daa4cd 628 Pfam PF17128 Domain of unknown function (DUF5107) 42 323 1.0E-46 T 09-03-2017 IPR033396 Domain of unknown function DUF5107 ARZXY2_RS13945 c1a20e6b33573617c6aa3edd52daa4cd 628 Gene3D G3DSA:1.25.40.10 458 596 1.6E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS13945 c1a20e6b33573617c6aa3edd52daa4cd 628 SUPERFAMILY SSF48452 459 596 1.44E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS04270 ffa6e7538ad24f0e357f9ebf73626855 206 Gene3D G3DSA:1.10.357.10 2 199 1.2E-39 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS04270 ffa6e7538ad24f0e357f9ebf73626855 206 SUPERFAMILY SSF48498 90 200 5.78E-19 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS04270 ffa6e7538ad24f0e357f9ebf73626855 206 SUPERFAMILY SSF46689 6 76 3.08E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04270 ffa6e7538ad24f0e357f9ebf73626855 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.5E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS04270 ffa6e7538ad24f0e357f9ebf73626855 206 Pfam PF13977 Bacterial transcriptional repressor 91 199 2.7E-14 T 09-03-2017 ARZXY2_RS00450 6a85a8f961936df80b9548416b592071 136 Pfam PF00581 Rhodanese-like domain 8 110 2.0E-6 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00450 6a85a8f961936df80b9548416b592071 136 Gene3D G3DSA:3.40.250.10 2 132 3.8E-36 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00450 6a85a8f961936df80b9548416b592071 136 SUPERFAMILY SSF52821 4 131 5.5E-16 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00450 6a85a8f961936df80b9548416b592071 136 SMART SM00450 7 118 1.2E-4 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 SUPERFAMILY SSF53182 2 212 1.16E-64 T 09-03-2017 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PIRSF PIRSF015592 1 211 1.1E-76 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 212 6.4E-76 T 09-03-2017 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 Pfam PF01470 Pyroglutamyl peptidase 2 200 1.2E-69 T 09-03-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 79 99 6.5E-46 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 6.5E-46 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 61 73 6.5E-46 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 131 147 6.5E-46 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 2 25 6.5E-46 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 Gene3D G3DSA:3.40.630.20 2 206 4.9E-63 T 09-03-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like ARZXY2_RS11265 e23a3c44848592ee4067076e428e903f 213 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 129 143 - T 09-03-2017 IPR033694 Pyroglutamyl peptidase I, Cys active site ARZXY2_RS15430 076adab9d225636929e42e7002f835a1 383 Gene3D G3DSA:1.50.10.10 60 254 8.9E-12 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS15430 076adab9d225636929e42e7002f835a1 383 Pfam PF03663 Glycosyl hydrolase family 76 57 331 1.2E-15 T 09-03-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 ARZXY2_RS15430 076adab9d225636929e42e7002f835a1 383 SUPERFAMILY SSF48208 56 335 2.3E-14 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 Pfam PF01895 PhoU domain 124 203 1.2E-9 T 09-03-2017 IPR026022 PhoU domain ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 Pfam PF01895 PhoU domain 17 103 9.2E-18 T 09-03-2017 IPR026022 PhoU domain ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 PIRSF PIRSF003107 1 215 2.4E-51 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 SUPERFAMILY SSF109755 2 213 1.47E-52 T 09-03-2017 ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 2.6E-50 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 Gene3D G3DSA:1.20.58.220 2 105 3.4E-27 T 09-03-2017 ARZXY2_RS14920 26248c593fe9f2d0f43a8f3350f88a6c 217 Gene3D G3DSA:1.20.58.220 114 211 1.0E-13 T 09-03-2017 ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 SMART SM00346 9 96 6.4E-24 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 Gene3D G3DSA:3.30.450.40 83 249 6.2E-55 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 SUPERFAMILY SSF55781 66 249 2.68E-45 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 Pfam PF09339 IclR helix-turn-helix domain 11 61 1.0E-16 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 Pfam PF01614 Bacterial transcriptional regulator 124 246 1.3E-27 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 SUPERFAMILY SSF46785 9 80 1.96E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01575 0909de7f857fb90138549f58c6e3f105 251 Gene3D G3DSA:1.10.10.10 7 82 3.3E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 357 375 2.7E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 537 562 2.7E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 505 521 2.7E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF81665 76 122 1.57E-10 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF81665 555 614 1.57E-10 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF81665 220 305 1.57E-10 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 519 3.1E-30 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 313 319 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 68 609 3.4E-140 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 68 607 2.1E-156 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF56784 310 394 5.36E-43 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF56784 422 606 5.36E-43 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 588 2.7E-68 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Gene3D G3DSA:2.70.150.10 72 220 4.3E-26 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Gene3D G3DSA:3.40.1110.10 336 407 1.3E-5 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 541 1.0E-23 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 442 1.0E-23 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 1.0E-23 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 1.0E-23 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 524 1.0E-23 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 SUPERFAMILY SSF81653 126 219 3.27E-22 T 09-03-2017 ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Gene3D G3DSA:3.40.50.1000 426 568 3.5E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Gene3D G3DSA:3.40.50.1000 284 327 3.5E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09830 f23cbc9df3f494ed2722861d78aff19e 641 Pfam PF00122 E1-E2 ATPase 90 302 1.0E-55 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 Gene3D G3DSA:3.40.50.1100 39 135 5.1E-40 T 09-03-2017 ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 295 2.3E-65 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 306 4.2E-131 T 09-03-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 SUPERFAMILY SSF53686 3 308 2.62E-101 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 306 5.1E-135 T 09-03-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 ARZXY2_RS07430 aa309fe18f3e8a48dbb0700a3ee43a0c 311 Gene3D G3DSA:3.40.50.1100 136 308 6.6E-74 T 09-03-2017 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 SUPERFAMILY SSF81271 277 358 1.26E-34 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Gene3D G3DSA:3.40.50.300 201 263 3.1E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Gene3D G3DSA:3.40.50.300 4 130 3.1E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Gene3D G3DSA:1.10.150.300 131 200 6.5E-20 T 09-03-2017 IPR023192 TGS-like domain ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Pfam PF06071 Protein of unknown function (DUF933) 277 358 9.4E-38 T 09-03-2017 IPR013029 Domain of unknown function DUF933 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Pfam PF01926 50S ribosome-binding GTPase 5 128 2.0E-22 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 361 42.43 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.7E-35 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.7E-35 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.7E-35 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.7E-35 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 359 6.0E-132 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 Gene3D G3DSA:3.10.20.30 264 359 6.5E-45 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 SUPERFAMILY SSF52540 3 299 2.39E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04145 dee23cfdc99cb39e0b4b5ea084d65517 369 PIRSF PIRSF006641 1 361 1.3E-140 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 146 210 1.1E-8 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 Gene3D G3DSA:3.30.360.10 335 389 1.2E-43 T 09-03-2017 ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 Gene3D G3DSA:3.30.360.10 153 292 1.2E-43 T 09-03-2017 ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 SUPERFAMILY SSF51735 5 163 7.43E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 Gene3D G3DSA:3.40.50.720 4 152 2.4E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 SUPERFAMILY SSF55347 138 318 7.36E-33 T 09-03-2017 ARZXY2_RS09730 cc04bf2777c435a0e5d289c9311d0223 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 134 6.7E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 Gene3D G3DSA:2.60.120.560 374 554 7.6E-27 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 Gene3D G3DSA:2.120.10.10 136 257 5.8E-10 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 81 392 2.2E-91 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 Gene3D G3DSA:2.115.10.20 87 135 2.2E-7 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 SUPERFAMILY SSF75005 72 394 9.1E-101 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 SMART SM00640 81 527 5.7E-131 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 451 527 1.3E-15 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS12570 078d72ad95a0eb36db5a558a70e2c83b 562 SUPERFAMILY SSF49899 414 554 1.11E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.2E-63 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 SUPERFAMILY SSF55424 340 459 1.56E-29 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 4.7E-34 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.7E-34 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 4.7E-34 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 4.7E-34 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 4.7E-34 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 Gene3D G3DSA:3.30.390.30 340 459 1.3E-30 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 6.2E-133 T 09-03-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 2.5E-24 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 Gene3D G3DSA:3.50.50.60 139 330 1.9E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 Gene3D G3DSA:3.50.50.60 8 138 4.1E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 SUPERFAMILY SSF51905 7 366 1.19E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 PIRSF PIRSF000350 1 452 3.6E-68 T 09-03-2017 ARZXY2_RS10675 af9d6deae665cdf43f5ab11981eb223c 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 321 4.1E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16000 6ff181797fb98ec4ed00d13f442c1344 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 285 9.7E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16000 6ff181797fb98ec4ed00d13f442c1344 293 SUPERFAMILY SSF161098 51 279 5.36E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16000 6ff181797fb98ec4ed00d13f442c1344 293 Gene3D G3DSA:1.10.3720.10 6 279 6.0E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 SUPERFAMILY SSF100950 3 218 1.58E-72 T 09-03-2017 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 09-03-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 215 1.1E-95 T 09-03-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 Gene3D G3DSA:3.40.810.20 3 217 5.4E-92 T 09-03-2017 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 Pfam PF01144 Coenzyme A transferase 7 206 3.6E-41 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS16525 37a664b44be9fb838caeb9e8fd7b2e59 232 SMART SM00882 6 209 6.0E-79 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS17355 b4a1ec1160659d127f85c1996d9d90e0 207 Pfam PF04299 Putative FMN-binding domain 1 166 9.2E-54 T 09-03-2017 IPR007396 Transcriptional regulator PAI 2-type ARZXY2_RS17355 b4a1ec1160659d127f85c1996d9d90e0 207 SUPERFAMILY SSF50475 10 192 4.91E-33 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS17355 b4a1ec1160659d127f85c1996d9d90e0 207 Gene3D G3DSA:2.30.110.10 1 198 1.1E-64 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS17355 b4a1ec1160659d127f85c1996d9d90e0 207 PIRSF PIRSF010372 1 207 5.9E-59 T 09-03-2017 IPR007396 Transcriptional regulator PAI 2-type ARZXY2_RS13820 99a7e329e1dad7f3905c672fe0823de6 334 Pfam PF01261 Xylose isomerase-like TIM barrel 39 242 1.2E-20 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS13820 99a7e329e1dad7f3905c672fe0823de6 334 SUPERFAMILY SSF51658 35 287 3.93E-36 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS13820 99a7e329e1dad7f3905c672fe0823de6 334 Gene3D G3DSA:3.20.20.150 35 304 3.3E-40 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS09665 1282cdb13d884f974f7b59974365cef6 487 Pfam PF13520 Amino acid permease 34 439 2.3E-26 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS09665 1282cdb13d884f974f7b59974365cef6 487 PIRSF PIRSF006060 7 479 3.8E-48 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 SUPERFAMILY SSF46565 6 84 5.76E-24 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 SMART SM00271 6 60 4.1E-18 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 Gene3D G3DSA:1.10.287.110 6 76 2.1E-21 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 PRINTS PR00625 DnaJ domain signature 60 79 1.8E-8 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 PRINTS PR00625 DnaJ domain signature 9 27 1.8E-8 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 PRINTS PR00625 DnaJ domain signature 27 42 1.8E-8 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 Pfam PF00226 DnaJ domain 8 65 3.2E-17 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS04645 0dc54e5fcf82df661fdef7d8891bd0ed 312 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 09-03-2017 IPR018253 DnaJ domain, conserved site ARZXY2_RS05085 7fad05328a01d69226ffc5f0a9715052 155 Gene3D G3DSA:1.10.10.10 22 92 3.0E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05085 7fad05328a01d69226ffc5f0a9715052 155 Pfam PF01475 Ferric uptake regulator family 23 139 3.8E-29 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 ARZXY2_RS05085 7fad05328a01d69226ffc5f0a9715052 155 SUPERFAMILY SSF46785 22 145 4.31E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16580 9762f8be610aa7e435416869aafdf139 294 Gene3D G3DSA:1.10.3720.10 18 282 4.0E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16580 9762f8be610aa7e435416869aafdf139 294 SUPERFAMILY SSF161098 23 294 1.31E-71 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16580 9762f8be610aa7e435416869aafdf139 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 287 2.4E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS08150 92d655f12fedecca7d2092b24f70bc04 108 Gene3D G3DSA:1.10.8.50 54 105 4.4E-8 T 09-03-2017 ARZXY2_RS08150 92d655f12fedecca7d2092b24f70bc04 108 SUPERFAMILY SSF46946 56 103 3.59E-5 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.1E-12 T 09-03-2017 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 2.1E-12 T 09-03-2017 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 2.1E-12 T 09-03-2017 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 2.1E-12 T 09-03-2017 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Gene3D G3DSA:3.20.20.70 393 736 2.1E-118 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Gene3D G3DSA:3.50.50.60 1 42 3.3E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Gene3D G3DSA:3.50.50.60 258 385 3.3E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Gene3D G3DSA:3.50.50.60 96 166 3.3E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Pfam PF01494 FAD binding domain 123 327 8.9E-17 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 396 733 8.7E-66 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 SUPERFAMILY SSF51905 1 150 2.59E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 SUPERFAMILY SSF51905 255 342 2.59E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS09425 49b8211503088fd70f1a32ce61f74d47 796 SUPERFAMILY SSF51395 394 739 1.73E-111 T 09-03-2017 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 Gene3D G3DSA:3.30.420.40 230 372 1.7E-43 T 09-03-2017 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 Pfam PF12802 MarR family 24 77 2.2E-8 T 09-03-2017 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 SUPERFAMILY SSF46785 20 103 2.07E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 Gene3D G3DSA:1.10.10.10 27 85 1.7E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 Pfam PF00480 ROK family 92 388 8.3E-57 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 SUPERFAMILY SSF53067 91 391 4.8E-52 T 09-03-2017 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 ProSitePatterns PS01125 ROK family signature. 225 252 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS13335 c2a4ed5f21d1efadaf75d410e0a353a7 395 Gene3D G3DSA:3.30.420.40 88 229 5.3E-41 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 Gene3D G3DSA:3.30.70.1150 84 164 4.5E-28 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 SUPERFAMILY SSF55021 2 76 2.24E-22 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 Pfam PF13710 ACT domain 12 74 3.1E-15 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 Gene3D G3DSA:3.30.70.260 1 79 1.0E-34 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.3E-24 T 09-03-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 6.2E-59 T 09-03-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 SUPERFAMILY SSF55021 80 162 3.04E-24 T 09-03-2017 ARZXY2_RS05630 02159c32963546bcccfbdb8775b05fdf 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 1.0E-36 T 09-03-2017 ARZXY2_RS14425 edcbb810cd1c650aa0e38589854f973f 80 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 47 2.0E-13 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 ARZXY2_RS14425 edcbb810cd1c650aa0e38589854f973f 80 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 1.9E-20 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 ARZXY2_RS14425 edcbb810cd1c650aa0e38589854f973f 80 Pfam PF02599 Global regulator protein family 1 52 4.3E-25 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 ARZXY2_RS14425 edcbb810cd1c650aa0e38589854f973f 80 Hamap MF_00167 Carbon storage regulator [csrA]. 1 70 19.11 T 09-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 ARZXY2_RS14425 edcbb810cd1c650aa0e38589854f973f 80 SUPERFAMILY SSF117130 1 53 1.44E-18 T 09-03-2017 ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 SMART SM00382 37 234 2.4E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 Pfam PF00005 ABC transporter 29 186 8.9E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 PIRSF PIRSF039085 9 262 6.0E-103 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 SUPERFAMILY SSF52540 12 256 8.54E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08480 83cf5039e4ec0b1283a23e03d029fb32 272 Gene3D G3DSA:3.40.50.300 11 257 7.8E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03505 78e06e466205068fba9e3209cc78af0f 101 Gene3D G3DSA:3.30.70.330 8 97 4.6E-33 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 ARZXY2_RS03505 78e06e466205068fba9e3209cc78af0f 101 Pfam PF00276 Ribosomal protein L23 11 91 3.7E-30 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03505 78e06e466205068fba9e3209cc78af0f 101 SUPERFAMILY SSF54189 7 92 1.37E-30 T 09-03-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03505 78e06e466205068fba9e3209cc78af0f 101 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 10 98 21.066 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11320 b6901fc3fdf2f3d6d4fc5c94a6d8881f 247 Gene3D G3DSA:3.20.20.70 10 243 1.2E-72 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS11320 b6901fc3fdf2f3d6d4fc5c94a6d8881f 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 10 243 33.851 T 09-03-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 ARZXY2_RS11320 b6901fc3fdf2f3d6d4fc5c94a6d8881f 247 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 9 244 1.6E-114 T 09-03-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 ARZXY2_RS11320 b6901fc3fdf2f3d6d4fc5c94a6d8881f 247 SUPERFAMILY SSF51366 10 242 1.49E-65 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS11320 b6901fc3fdf2f3d6d4fc5c94a6d8881f 247 Pfam PF00977 Histidine biosynthesis protein 11 236 1.4E-64 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 Gene3D G3DSA:2.30.38.10 310 366 1.5E-7 T 09-03-2017 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 Gene3D G3DSA:3.40.50.980 140 296 6.2E-25 T 09-03-2017 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 SUPERFAMILY SSF56801 11 458 5.49E-67 T 09-03-2017 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 SUPERFAMILY SSF47336 477 517 5.63E-5 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 Pfam PF00501 AMP-binding enzyme 14 373 1.8E-41 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 Gene3D G3DSA:3.40.50.980 12 139 1.9E-10 T 09-03-2017 ARZXY2_RS19580 ca8257dfb66c417c00a284d139255094 862 Gene3D G3DSA:1.10.1200.10 477 517 1.4E-5 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS03125 d2d54ed7dade24c0b8bd5ec488a6d3ab 444 SUPERFAMILY SSF53850 44 364 1.14E-49 T 09-03-2017 ARZXY2_RS03125 d2d54ed7dade24c0b8bd5ec488a6d3ab 444 Pfam PF01547 Bacterial extracellular solute-binding protein 57 338 4.2E-31 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS03125 d2d54ed7dade24c0b8bd5ec488a6d3ab 444 Gene3D G3DSA:3.40.190.10 172 347 1.8E-28 T 09-03-2017 ARZXY2_RS03125 d2d54ed7dade24c0b8bd5ec488a6d3ab 444 Gene3D G3DSA:3.40.190.10 43 171 2.6E-13 T 09-03-2017 ARZXY2_RS11995 75b3026ba11de700201f07f8698d812b 939 Gene3D G3DSA:1.25.10.10 531 675 1.0E-5 T 09-03-2017 IPR011989 Armadillo-like helical ARZXY2_RS11995 75b3026ba11de700201f07f8698d812b 939 SUPERFAMILY SSF48371 511 754 2.38E-8 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 2.4E-36 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 2.4E-36 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 2.4E-36 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 2.4E-36 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 2.4E-36 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 SUPERFAMILY SSF48179 160 290 8.16E-40 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 SUPERFAMILY SSF51735 2 149 6.03E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 Gene3D G3DSA:3.40.50.720 2 163 4.6E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 Gene3D G3DSA:1.10.1040.10 164 271 6.1E-35 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 271 1.8E-24 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 09-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 294 7.4E-98 T 09-03-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 SMART SM01350 162 290 8.6E-6 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 ARZXY2_RS18560 1e02f923fb1eb76c6c1e1d1739baf44c 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 1.4E-34 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS15035 17aa93766980db033c6f06534aac6c26 180 Pfam PF10400 Virulence activator alpha C-term 91 169 2.8E-9 T 09-03-2017 IPR018309 Transcription regulator PadR, C-terminal ARZXY2_RS15035 17aa93766980db033c6f06534aac6c26 180 Gene3D G3DSA:1.10.10.10 1 83 2.1E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15035 17aa93766980db033c6f06534aac6c26 180 SUPERFAMILY SSF46785 3 169 2.57E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15035 17aa93766980db033c6f06534aac6c26 180 Pfam PF03551 Transcriptional regulator PadR-like family 7 76 9.6E-18 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS18000 6541f33fd586766f9952b4ebc45d12e6 337 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 18 83 4.6E-6 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 SUPERFAMILY SSF90123 32 345 9.68E-70 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 SMART SM00382 388 581 5.3E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 Pfam PF00005 ABC transporter 382 528 3.1E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 Gene3D G3DSA:3.40.50.300 363 596 8.0E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 SUPERFAMILY SSF52540 352 603 4.44E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 Pfam PF00664 ABC transporter transmembrane region 44 316 2.5E-40 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01700 579523aec090bf4ee49e28ad3a0a80d3 610 Gene3D G3DSA:1.20.1560.10 32 349 1.3E-71 T 09-03-2017 ARZXY2_RS15685 659ca7c32508589ff7757bb45ff084ad 130 SUPERFAMILY SSF52402 1 128 1.0E-23 T 09-03-2017 ARZXY2_RS15685 659ca7c32508589ff7757bb45ff084ad 130 Pfam PF00582 Universal stress protein family 2 128 1.8E-20 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS15685 659ca7c32508589ff7757bb45ff084ad 130 Gene3D G3DSA:3.40.50.620 2 128 5.4E-26 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS15685 659ca7c32508589ff7757bb45ff084ad 130 PRINTS PR01438 Universal stress protein signature 106 128 2.3E-10 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS15685 659ca7c32508589ff7757bb45ff084ad 130 PRINTS PR01438 Universal stress protein signature 88 100 2.3E-10 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS11190 03ae8804d4d5e878e6e8b02a8ebce065 247 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 13 213 7.3E-38 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type ARZXY2_RS11190 03ae8804d4d5e878e6e8b02a8ebce065 247 Gene3D G3DSA:1.20.120.450 3 121 5.3E-7 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase ARZXY2_RS11190 03ae8804d4d5e878e6e8b02a8ebce065 247 SUPERFAMILY SSF109854 2 153 1.4E-31 T 09-03-2017 ARZXY2_RS11190 03ae8804d4d5e878e6e8b02a8ebce065 247 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 148 4.8E-18 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 ARZXY2_RS11190 03ae8804d4d5e878e6e8b02a8ebce065 247 SUPERFAMILY SSF55718 156 237 2.71E-6 T 09-03-2017 IPR003033 SCP2 sterol-binding domain ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 15 317 47.392 T 09-03-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 Gene3D G3DSA:3.40.50.720 19 221 4.4E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 Gene3D G3DSA:3.90.25.10 296 318 7.8E-10 T 09-03-2017 ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 Gene3D G3DSA:3.90.25.10 222 243 7.8E-10 T 09-03-2017 ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 249 8.2E-72 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS02485 e0679cf15970358917ab7b3d9e245b18 324 SUPERFAMILY SSF51735 19 319 2.6E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 Pfam PF01546 Peptidase family M20/M25/M40 101 439 1.7E-32 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 Gene3D G3DSA:3.40.630.10 26 223 2.6E-55 T 09-03-2017 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 Gene3D G3DSA:3.40.630.10 386 446 2.6E-55 T 09-03-2017 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 100 109 - T 09-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 SUPERFAMILY SSF53187 357 446 7.65E-51 T 09-03-2017 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 SUPERFAMILY SSF53187 15 202 7.65E-51 T 09-03-2017 ARZXY2_RS16410 6853fc7a8ca9f4f010d513d313ac9ca9 464 Gene3D G3DSA:3.30.70.360 224 337 5.1E-4 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS02205 17cab43979bf736e0e8e4edcd803d9f5 101 Pfam PF14012 Protein of unknown function (DUF4229) 4 65 5.8E-16 T 09-03-2017 IPR025323 Protein of unknown function DUF4229 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 SUPERFAMILY SSF53822 72 338 5.07E-72 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 Gene3D G3DSA:3.40.50.2300 183 316 7.3E-45 T 09-03-2017 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 SUPERFAMILY SSF47413 12 71 1.27E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 Gene3D G3DSA:1.10.260.40 13 65 2.9E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 SMART SM00354 12 83 1.2E-27 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 Gene3D G3DSA:3.40.50.2300 66 182 6.4E-42 T 09-03-2017 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 Pfam PF13377 Periplasmic binding protein-like domain 179 336 7.3E-35 T 09-03-2017 ARZXY2_RS01770 16daaf6f76ff75a324715f6fddd048a8 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 16 60 2.3E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 22 193 3.1E-24 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 Gene3D G3DSA:1.10.150.240 34 76 5.3E-10 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 4.9E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 19 30 4.9E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 4.9E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 4.9E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 21 193 4.9E-22 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 SUPERFAMILY SSF56784 19 201 9.34E-43 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS15225 02166e8d1b991313987f72e583263640 234 Gene3D G3DSA:3.40.50.1000 77 217 2.4E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Gene3D G3DSA:3.30.43.10 6 67 2.5E-21 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 355 74.905 T 09-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Pfam PF01565 FAD binding domain 21 146 1.8E-20 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 6 352 1.0E-48 T 09-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 SUPERFAMILY SSF56194 217 353 1.57E-30 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 218 351 6.8E-35 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 SUPERFAMILY SSF56176 7 187 2.01E-33 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Gene3D G3DSA:3.30.465.10 229 246 7.6E-46 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Gene3D G3DSA:3.30.465.10 77 195 7.6E-46 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS03255 bbfecc1d6ab646fabd5d89bcdb8127f3 355 Gene3D G3DSA:3.90.78.10 247 354 9.5E-42 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS15030 c74d999c17b05ec8b6fbe4e9fb33f49f 756 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 500 628 1.4E-30 T 09-03-2017 IPR025299 CstA, C-terminal domain ARZXY2_RS15030 c74d999c17b05ec8b6fbe4e9fb33f49f 756 Pfam PF02554 Carbon starvation protein CstA 65 443 1.5E-162 T 09-03-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 ARZXY2_RS00210 591a0ea34bbd789e525a4225c8f41646 115 Pfam PF05336 Domain of unknown function (DUF718) 2 103 6.8E-26 T 09-03-2017 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 ARZXY2_RS00210 591a0ea34bbd789e525a4225c8f41646 115 SUPERFAMILY SSF54909 1 103 2.06E-27 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS16425 e0f1ed1a7b1ad9f9f4372f52a676e3a7 251 SMART SM00382 26 211 6.5E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS16425 e0f1ed1a7b1ad9f9f4372f52a676e3a7 251 Gene3D G3DSA:3.40.50.300 2 219 3.7E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16425 e0f1ed1a7b1ad9f9f4372f52a676e3a7 251 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS16425 e0f1ed1a7b1ad9f9f4372f52a676e3a7 251 SUPERFAMILY SSF52540 2 232 5.9E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16425 e0f1ed1a7b1ad9f9f4372f52a676e3a7 251 Pfam PF00005 ABC transporter 19 162 1.9E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 Gene3D G3DSA:3.40.1280.10 1 163 6.7E-68 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 267 103.672 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 SUPERFAMILY SSF75217 1 234 3.73E-93 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 224 2.9E-67 T 09-03-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 Gene3D G3DSA:1.10.1270.20 164 249 1.4E-31 T 09-03-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 231 8.6E-80 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ARZXY2_RS07020 88c6ba3532cd32ee0d7c7fedd6d3fa34 267 PIRSF PIRSF000386 1 248 9.3E-94 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 SUPERFAMILY SSF53187 180 502 1.57E-109 T 09-03-2017 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 346 353 - T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 4.2E-50 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 4.2E-50 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 4.2E-50 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 4.2E-50 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 4.2E-50 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 25 149 2.0E-18 T 09-03-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 Gene3D G3DSA:3.40.630.10 179 502 8.0E-129 T 09-03-2017 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 SUPERFAMILY SSF52949 22 169 9.42E-23 T 09-03-2017 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 Gene3D G3DSA:3.40.220.10 21 178 1.4E-28 T 09-03-2017 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 496 8.4E-112 T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 ARZXY2_RS10670 bea683443b12a33196a8e2366232b62f 507 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 9 504 33.228 T 09-03-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 1.0E-7 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 Pfam PF13602 Zinc-binding dehydrogenase 188 303 1.6E-19 T 09-03-2017 ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 SUPERFAMILY SSF51735 119 280 3.2E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 Gene3D G3DSA:3.90.180.10 1 150 3.5E-46 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 SUPERFAMILY SSF50129 1 151 1.83E-38 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 SMART SM00829 10 303 1.1E-28 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS16025 3fbe6890a5485bd9eba292e2e6891127 306 Gene3D G3DSA:3.40.50.720 151 239 1.3E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10910 f14984f979473175f9865524267f1308 364 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS10910 f14984f979473175f9865524267f1308 364 SUPERFAMILY SSF48576 19 362 1.98E-75 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS10910 f14984f979473175f9865524267f1308 364 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 242 254 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS10910 f14984f979473175f9865524267f1308 364 Gene3D G3DSA:1.10.600.10 21 362 8.2E-84 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS10910 f14984f979473175f9865524267f1308 364 Pfam PF00348 Polyprenyl synthetase 47 313 1.6E-53 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS04090 2d5097a0cc1e061c05403a89b087b7d8 364 SMART SM00382 31 217 8.1E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04090 2d5097a0cc1e061c05403a89b087b7d8 364 Pfam PF00005 ABC transporter 23 167 3.6E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04090 2d5097a0cc1e061c05403a89b087b7d8 364 SUPERFAMILY SSF52540 5 243 5.46E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04090 2d5097a0cc1e061c05403a89b087b7d8 364 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04090 2d5097a0cc1e061c05403a89b087b7d8 364 Gene3D G3DSA:3.40.50.300 4 240 1.4E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07500 31edde03f9dc133cc6028f657ee92ab6 228 SUPERFAMILY SSF48371 13 225 2.49E-54 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 ARZXY2_RS07500 31edde03f9dc133cc6028f657ee92ab6 228 Gene3D G3DSA:1.25.40.290 131 226 1.0E-34 T 09-03-2017 ARZXY2_RS07500 31edde03f9dc133cc6028f657ee92ab6 228 Pfam PF08713 DNA alkylation repair enzyme 10 225 3.6E-62 T 09-03-2017 IPR014825 DNA alkylation repair enzyme ARZXY2_RS15960 663a972fdcd27863bad60623cc2e0511 131 Pfam PF04237 YjbR 11 112 5.5E-27 T 09-03-2017 IPR007351 Uncharacterised protein YjbR ARZXY2_RS15960 663a972fdcd27863bad60623cc2e0511 131 SUPERFAMILY SSF142906 1 127 4.58E-39 T 09-03-2017 ARZXY2_RS19210 aea5b6d46b25a3288e882938e0181faf 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 307 1.1E-38 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS16495 1638502a0a1d81608d26e4e859a7cf46 682 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 145 614 1.2E-147 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS16495 1638502a0a1d81608d26e4e859a7cf46 682 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 108 614 4.0E-171 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS16495 1638502a0a1d81608d26e4e859a7cf46 682 ProSitePatterns PS01303 BCCT family of transporters signature. 414 423 - T 09-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12900 bb260fff88c76d84acd136af307d43e4 1111 SUPERFAMILY SSF53448 3 250 5.06E-39 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS12900 bb260fff88c76d84acd136af307d43e4 1111 Pfam PF13641 Glycosyltransferase like family 2 5 229 2.6E-20 T 09-03-2017 ARZXY2_RS12900 bb260fff88c76d84acd136af307d43e4 1111 Gene3D G3DSA:3.90.550.10 3 244 2.6E-40 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Gene3D G3DSA:3.40.50.300 8 105 3.9E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Gene3D G3DSA:3.40.50.300 140 287 3.9E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 557 1.6E-278 T 09-03-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Pfam PF00005 ABC transporter 340 473 1.1E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Pfam PF00005 ABC transporter 21 190 5.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Gene3D G3DSA:3.40.50.300 322 513 8.3E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 SUPERFAMILY SSF52540 301 509 1.33E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 SMART SM00382 30 242 1.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 SMART SM00382 348 522 3.6E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 SUPERFAMILY SSF52540 13 243 8.98E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07520 c7ff393d152936fb6d073a98e7fb8b35 560 Pfam PF12848 ABC transporter 230 299 2.0E-12 T 09-03-2017 IPR032781 ABC-transporter extension domain ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Gene3D G3DSA:3.40.50.920 570 700 7.9E-47 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 353 3.0E-130 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 SUPERFAMILY SSF52922 565 702 7.33E-39 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Pfam PF02780 Transketolase, C-terminal domain 587 692 1.2E-13 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Gene3D G3DSA:3.40.50.970 349 554 2.4E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 ProSitePatterns PS00801 Transketolase signature 1. 20 40 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 TIGRFAM TIGR00232 tktlase_bact: transketolase 14 698 3.6E-225 T 09-03-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 SUPERFAMILY SSF52518 5 339 3.54E-96 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 SMART SM00861 369 549 3.8E-64 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 SUPERFAMILY SSF52518 357 550 5.11E-65 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Pfam PF02779 Transketolase, pyrimidine binding domain 368 548 6.7E-42 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS09030 605fbbb3c35df662fab7b41d46ece998 705 Gene3D G3DSA:3.40.50.970 9 339 2.8E-106 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 SUPERFAMILY SSF52540 572 793 1.05E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 Pfam PF01580 FtsK/SpoIIIE family 581 793 1.6E-29 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 Gene3D G3DSA:3.40.50.300 589 793 9.6E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 Gene3D G3DSA:2.60.200.20 82 143 2.2E-6 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 SMART SM00382 1232 1345 0.0044 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 SMART SM00382 609 784 1.9E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 Gene3D G3DSA:3.40.50.300 1228 1255 1.5E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 SUPERFAMILY SSF52540 1230 1331 1.73E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04835 11d916ed4fab5a8c8bef866094ccda14 1399 SUPERFAMILY SSF49879 84 142 9.12E-6 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS16860 689d666468c640535025b568fb97c80b 296 SUPERFAMILY SSF51695 10 289 3.66E-60 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS16860 689d666468c640535025b568fb97c80b 296 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 16 285 1.2E-35 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ARZXY2_RS16860 689d666468c640535025b568fb97c80b 296 Gene3D G3DSA:3.20.20.190 8 291 2.2E-61 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS10660 8b18b36f61009a5cceaead35eaf0111e 448 Gene3D G3DSA:1.20.1250.20 5 194 6.0E-26 T 09-03-2017 ARZXY2_RS10660 8b18b36f61009a5cceaead35eaf0111e 448 SUPERFAMILY SSF103473 3 412 9.68E-51 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS10660 8b18b36f61009a5cceaead35eaf0111e 448 Pfam PF07690 Major Facilitator Superfamily 15 359 8.9E-36 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS10660 8b18b36f61009a5cceaead35eaf0111e 448 Gene3D G3DSA:1.20.1250.20 226 412 2.4E-12 T 09-03-2017 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 Gene3D G3DSA:1.10.260.40 5 56 3.2E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 Pfam PF13377 Periplasmic binding protein-like domain 171 333 2.3E-29 T 09-03-2017 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 Gene3D G3DSA:3.40.50.2300 57 174 3.7E-40 T 09-03-2017 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 8.9E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 SUPERFAMILY SSF53822 63 335 3.73E-58 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 Gene3D G3DSA:3.40.50.2300 175 310 1.1E-37 T 09-03-2017 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 SMART SM00354 4 74 1.3E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00215 8b99d3952e363d8882ecafea06a9b013 338 SUPERFAMILY SSF47413 4 62 5.53E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 SUPERFAMILY SSF54211 20 169 2.43E-28 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 Hamap MF_00384 Homoserine kinase [thrB]. 20 319 28.521 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 Gene3D G3DSA:3.30.70.890 181 297 5.5E-33 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 Pfam PF00288 GHMP kinases N terminal domain 102 160 1.4E-11 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 Gene3D G3DSA:3.30.230.10 19 171 5.3E-52 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 SUPERFAMILY SSF55060 182 297 6.47E-25 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PIRSF PIRSF000676 16 322 2.1E-80 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 TIGRFAM TIGR00191 thrB: homoserine kinase 20 320 3.9E-66 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PRINTS PR00958 Homoserine kinase signature 263 278 4.7E-39 T 09-03-2017 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PRINTS PR00958 Homoserine kinase signature 111 126 4.7E-39 T 09-03-2017 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PRINTS PR00958 Homoserine kinase signature 186 203 4.7E-39 T 09-03-2017 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PRINTS PR00958 Homoserine kinase signature 27 42 4.7E-39 T 09-03-2017 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 PRINTS PR00958 Homoserine kinase signature 147 160 4.7E-39 T 09-03-2017 ARZXY2_RS05180 04f8f4af0962bc6559a2a1595af31dec 324 Pfam PF08544 GHMP kinases C terminal 242 288 3.1E-6 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain ARZXY2_RS13735 e577f766f72a374302ef9ea1884b1c46 254 Pfam PF03746 LamB/YcsF family 19 251 1.2E-84 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF ARZXY2_RS13735 e577f766f72a374302ef9ea1884b1c46 254 SUPERFAMILY SSF88713 18 252 4.22E-75 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 2 10 8.3E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 22 41 8.3E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 Gene3D G3DSA:3.40.50.720 1 54 1.4E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 SUPERFAMILY SSF51735 1 54 6.8E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 54 5.5E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 41 5.5E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 13 5.5E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 Pfam PF00106 short chain dehydrogenase 1 54 2.5E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS21455 e9e0f6f36f5fea972de44616eb3a1433 54 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 9 37 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS02955 87f38612ce6a2459a64de20bda2aa87e 360 SUPERFAMILY SSF103481 245 338 2.48E-9 T 09-03-2017 ARZXY2_RS02955 87f38612ce6a2459a64de20bda2aa87e 360 TIGRFAM TIGR00688 rarD: protein RarD 61 314 5.8E-58 T 09-03-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 ARZXY2_RS02955 87f38612ce6a2459a64de20bda2aa87e 360 SUPERFAMILY SSF103481 101 197 7.06E-11 T 09-03-2017 ARZXY2_RS02955 87f38612ce6a2459a64de20bda2aa87e 360 Pfam PF00892 EamA-like transporter family 60 196 8.9E-9 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS02955 87f38612ce6a2459a64de20bda2aa87e 360 Pfam PF00892 EamA-like transporter family 205 338 8.6E-8 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 PIRSF PIRSF037980 99 981 0.0 T 09-03-2017 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Pfam PF12831 FAD dependent oxidoreductase 127 170 1.1E-10 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 256 1.3E-5 T 09-03-2017 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 149 1.3E-5 T 09-03-2017 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 SUPERFAMILY SSF101790 884 980 3.11E-10 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 865 966 2.5E-12 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:2.40.30.110 883 980 2.7E-13 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Pfam PF01571 Aminomethyltransferase folate-binding domain 590 859 4.0E-74 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 102 2.2E-15 T 09-03-2017 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:3.30.70.1400 643 718 7.6E-23 T 09-03-2017 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:3.30.1360.120 735 837 9.0E-34 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:3.30.1360.120 585 642 9.0E-34 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:3.50.50.60 119 273 4.1E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 Gene3D G3DSA:3.50.50.60 316 401 4.1E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 SUPERFAMILY SSF103025 583 876 7.06E-91 T 09-03-2017 ARZXY2_RS20350 49c3e3f7a15158d788a059ed2f6e1502 981 SUPERFAMILY SSF51905 125 402 9.72E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12040 79f265be9313912a1e8983204adb6f4f 233 Pfam PF01391 Collagen triple helix repeat (20 copies) 106 156 2.6E-9 T 09-03-2017 IPR008160 Collagen triple helix repeat ARZXY2_RS00675 ba73f7bb35bef5e9c50732cdd07a4cd4 526 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 142 1.2E-28 T 09-03-2017 IPR032093 Phospholipase D, N-terminal ARZXY2_RS00675 ba73f7bb35bef5e9c50732cdd07a4cd4 526 Gene3D G3DSA:3.60.21.10 133 500 2.6E-12 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS00675 ba73f7bb35bef5e9c50732cdd07a4cd4 526 Pfam PF09423 PhoD-like phosphatase 155 497 1.4E-111 T 09-03-2017 IPR018946 Alkaline phosphatase D-related ARZXY2_RS00675 ba73f7bb35bef5e9c50732cdd07a4cd4 526 SUPERFAMILY SSF56300 155 501 2.88E-31 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 Gene3D G3DSA:3.20.20.70 4 221 2.5E-90 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 217 9.2E-79 T 09-03-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 Pfam PF01791 DeoC/LacD family aldolase 10 217 3.5E-19 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 5 221 36.065 T 09-03-2017 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 SMART SM01133 6 219 7.3E-95 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 PIRSF PIRSF001357 2 225 1.6E-75 T 09-03-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 ARZXY2_RS12670 f11c237c3ec94f735335dcd14309511e 226 SUPERFAMILY SSF51569 5 219 3.98E-81 T 09-03-2017 ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 Gene3D G3DSA:3.40.50.300 12 233 7.8E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 SUPERFAMILY SSF52540 12 233 7.21E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 ProSitePatterns PS00211 ABC transporters family signature. 416 430 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 SUPERFAMILY SSF52540 256 501 2.25E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 SMART SM00382 296 494 3.2E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 SMART SM00382 37 235 2.8E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 Gene3D G3DSA:3.40.50.300 268 508 3.8E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 Pfam PF00005 ABC transporter 288 443 2.1E-16 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13340 c0e912503ab8e1b0d0e6739485486686 519 Pfam PF00005 ABC transporter 28 179 1.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 SUPERFAMILY SSF52518 51 233 5.38E-60 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Gene3D G3DSA:3.40.50.1220 240 403 1.3E-62 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 SUPERFAMILY SSF52518 423 631 4.29E-67 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 244 379 8.5E-45 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Gene3D G3DSA:3.40.50.970 404 613 5.2E-74 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 480 499 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 55 619 2.4E-224 T 09-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Gene3D G3DSA:3.40.50.970 55 230 5.3E-73 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 SUPERFAMILY SSF52467 237 411 1.46E-57 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 55 217 5.9E-55 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS05625 7543559bd59ca5471fddeeab4357a086 633 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 443 598 1.1E-50 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 183 273 1.3E-17 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 301 655 1.2E-103 T 09-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 131 8.0E-33 T 09-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 SUPERFAMILY SSF52794 180 277 2.27E-30 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 144 2.8E-31 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 Gene3D G3DSA:3.40.930.10 2 147 1.5E-39 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 Gene3D G3DSA:3.40.50.2300 178 278 1.6E-37 T 09-03-2017 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 182 264 3.9E-25 T 09-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 ARZXY2_RS17235 08dc8c4c9ff029a61ac5fee318d3a1c4 675 SUPERFAMILY SSF55804 2 145 6.15E-32 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ARZXY2_RS18435 ca93354fde6f32051c431f631f939cf6 485 Gene3D G3DSA:3.90.1310.10 75 142 1.7E-7 T 09-03-2017 ARZXY2_RS18435 ca93354fde6f32051c431f631f939cf6 485 Gene3D G3DSA:3.40.710.10 143 484 5.1E-84 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18435 ca93354fde6f32051c431f631f939cf6 485 SUPERFAMILY SSF56601 138 484 1.79E-75 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18435 ca93354fde6f32051c431f631f939cf6 485 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 481 3.0E-60 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 Pfam PF01266 FAD dependent oxidoreductase 30 425 3.3E-41 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 447 570 2.8E-18 T 09-03-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 SUPERFAMILY SSF51905 310 377 3.24E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 SUPERFAMILY SSF51905 29 279 3.24E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 Gene3D G3DSA:3.50.50.60 27 294 8.0E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 28 40 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 57 69 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 370 376 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 102 114 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 41 51 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS08205 5f395f882cea59cdb014f7c6dcaec8dd 595 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 414 426 1.7E-19 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 1.7E-94 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 SUPERFAMILY SSF52029 182 373 5.08E-79 T 09-03-2017 IPR027409 GroEL-like apical domain ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 8.0E-236 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 SUPERFAMILY SSF54849 140 200 3.66E-20 T 09-03-2017 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 Gene3D G3DSA:1.10.560.10 366 518 1.3E-38 T 09-03-2017 IPR027413 GroEL-like equatorial domain ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 Gene3D G3DSA:1.10.560.10 3 185 6.1E-41 T 09-03-2017 IPR027413 GroEL-like equatorial domain ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 PRINTS PR00298 60kDa chaperonin signature 347 372 7.3E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 PRINTS PR00298 60kDa chaperonin signature 26 52 7.3E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 PRINTS PR00298 60kDa chaperonin signature 82 109 7.3E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 PRINTS PR00298 60kDa chaperonin signature 265 288 7.3E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 PRINTS PR00298 60kDa chaperonin signature 395 416 7.3E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 Hamap MF_00600 60 kDa chaperonin [groL]. 1 535 39.424 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 SUPERFAMILY SSF48592 403 521 4.75E-71 T 09-03-2017 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 SUPERFAMILY SSF48592 7 133 4.75E-71 T 09-03-2017 ARZXY2_RS03880 7445c1174c06f6105b6e6ac716067270 537 Gene3D G3DSA:3.50.7.10 186 365 5.7E-92 T 09-03-2017 IPR027409 GroEL-like apical domain ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 SUPERFAMILY SSF52279 398 644 3.92E-44 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 Gene3D G3DSA:3.20.20.300 14 368 3.8E-99 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 Gene3D G3DSA:3.40.50.1700 385 644 2.2E-56 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 Pfam PF14310 Fibronectin type III-like domain 678 747 3.2E-17 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 PRINTS PR00133 Glycosyl hydrolase family 3 signature 174 190 2.9E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 PRINTS PR00133 Glycosyl hydrolase family 3 signature 105 121 2.9E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 PRINTS PR00133 Glycosyl hydrolase family 3 signature 276 294 2.9E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 PRINTS PR00133 Glycosyl hydrolase family 3 signature 128 147 2.9E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 PRINTS PR00133 Glycosyl hydrolase family 3 signature 205 221 2.9E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 399 641 1.1E-39 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 SUPERFAMILY SSF51445 13 397 1.9E-95 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 SMART SM01217 678 747 8.0E-24 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS13650 3275444f3a547258ef9146f1635fbbd8 781 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 28 356 3.5E-74 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 SUPERFAMILY SSF52540 5 232 3.14E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 SMART SM00382 29 235 3.8E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 SMART SM00382 372 535 5.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 Gene3D G3DSA:3.40.50.300 5 93 3.7E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 Gene3D G3DSA:3.40.50.300 125 262 3.7E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 Gene3D G3DSA:3.40.50.300 364 530 2.1E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 Pfam PF00005 ABC transporter 364 492 2.8E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 Pfam PF00005 ABC transporter 21 190 9.8E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02250 d03ba64d9dd6ce8e89d5db617524a72d 553 SUPERFAMILY SSF52540 349 530 1.41E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 SUPERFAMILY SSF53187 250 486 8.86E-67 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 SUPERFAMILY SSF53187 46 98 8.86E-67 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 Pfam PF02225 PA domain 144 243 1.0E-15 T 09-03-2017 IPR003137 PA domain ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 Gene3D G3DSA:3.50.30.30 130 255 2.0E-19 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 Gene3D G3DSA:3.40.630.10 45 109 1.9E-73 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 Gene3D G3DSA:3.40.630.10 265 488 1.9E-73 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 SUPERFAMILY SSF52025 130 208 3.14E-13 T 09-03-2017 ARZXY2_RS02730 1c892d145c0501b2d52a1a535b7892aa 514 Pfam PF04389 Peptidase family M28 266 481 2.5E-45 T 09-03-2017 IPR007484 Peptidase M28 ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 SUPERFAMILY SSF52540 1 220 7.14E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 Pfam PF00005 ABC transporter 19 166 3.4E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 Gene3D G3DSA:3.40.50.300 1 220 2.0E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 SMART SM00382 28 215 6.8E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 2.4E-85 T 09-03-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 ARZXY2_RS04955 ca02ddb1758ddb517d0c53bebc4cec70 254 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS03605 cd5fbd691bc2fd737a092653e2a88fd5 267 Pfam PF00535 Glycosyl transferase family 2 22 159 7.8E-22 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS03605 cd5fbd691bc2fd737a092653e2a88fd5 267 SUPERFAMILY SSF53448 19 253 6.33E-37 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS03605 cd5fbd691bc2fd737a092653e2a88fd5 267 Gene3D G3DSA:3.90.550.10 23 240 1.3E-31 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS07300 cd2872b5e4124e09dde5e4dead64517a 294 Pfam PF01078 Magnesium chelatase, subunit ChlI 6 184 3.7E-72 T 09-03-2017 IPR000523 Magnesium chelatase ChlI domain ARZXY2_RS07300 cd2872b5e4124e09dde5e4dead64517a 294 SUPERFAMILY SSF52540 7 291 2.66E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07300 cd2872b5e4124e09dde5e4dead64517a 294 Gene3D G3DSA:3.40.50.300 7 176 5.4E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07300 cd2872b5e4124e09dde5e4dead64517a 294 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 193 288 2.8E-24 T 09-03-2017 IPR025158 Mg chelatase-related protein, C-terminal domain ARZXY2_RS10860 7358a83cfaeb43a92b0ead0543cc7d6b 369 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 357 5.5E-88 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS10860 7358a83cfaeb43a92b0ead0543cc7d6b 369 Pfam PF00953 Glycosyl transferase family 4 88 287 3.0E-36 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 ARZXY2_RS10860 7358a83cfaeb43a92b0ead0543cc7d6b 369 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 362 22.686 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS10860 7358a83cfaeb43a92b0ead0543cc7d6b 369 ProSitePatterns PS01348 MraY family signature 2. 188 199 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS08940 449e9326aad6a6346468118380579016 161 Pfam PF04073 Aminoacyl-tRNA editing domain 33 151 2.7E-27 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS08940 449e9326aad6a6346468118380579016 161 SUPERFAMILY SSF55826 15 160 9.94E-33 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS08940 449e9326aad6a6346468118380579016 161 Gene3D G3DSA:3.90.960.10 14 160 1.5E-38 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 ARZXY2_RS17870 c7f842c478ac660b9b438224d4423083 284 SUPERFAMILY SSF53474 2 282 1.96E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17870 c7f842c478ac660b9b438224d4423083 284 Gene3D G3DSA:3.40.50.1820 3 275 6.5E-23 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17870 c7f842c478ac660b9b438224d4423083 284 Pfam PF12697 Alpha/beta hydrolase family 30 237 1.1E-10 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 Gene3D G3DSA:1.25.40.10 182 256 4.1E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 SUPERFAMILY SSF52833 61 164 5.26E-14 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 Gene3D G3DSA:3.40.30.10 61 162 1.2E-10 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 Pfam PF14561 Tetratricopeptide repeat 242 328 3.6E-20 T 09-03-2017 ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 Pfam PF00085 Thioredoxin 62 160 2.0E-5 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 Gene3D G3DSA:1.25.40.10 257 328 1.4E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS05320 dd804bc3b097f62d215aafcde9931ba7 328 SUPERFAMILY SSF48452 182 277 5.01E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 SUPERFAMILY SSF55681 11 210 6.21E-59 T 09-03-2017 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 39 207 7.4E-37 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 72 87 - T 09-03-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 Gene3D G3DSA:3.90.1550.10 12 208 9.0E-67 T 09-03-2017 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 Hamap MF_00013 Octanoyltransferase [lipB]. 2 213 31.07 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 PIRSF PIRSF016262 3 218 9.6E-58 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 128 6.0E-21 T 09-03-2017 ARZXY2_RS10710 13dedc1c55687de6b6a5800c7152d420 222 Pfam PF03099 Biotin/lipoate A/B protein ligase family 65 163 1.5E-8 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 SUPERFAMILY SSF52768 19 374 5.28E-98 T 09-03-2017 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01270 Histone deacetylase superfamily signature 263 273 2.2E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01270 Histone deacetylase superfamily signature 144 167 2.2E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01270 Histone deacetylase superfamily signature 177 192 2.2E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01272 Acetoin utilisation ACUC protein signature 121 134 5.7E-11 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01272 Acetoin utilisation ACUC protein signature 100 114 5.7E-11 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 PRINTS PR01272 Acetoin utilisation ACUC protein signature 30 50 5.7E-11 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 Pfam PF00850 Histone deacetylase domain 36 331 4.7E-71 T 09-03-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 ARZXY2_RS01930 c69aaba68b58d8585b64cf15e2faf114 408 Gene3D G3DSA:3.40.800.20 13 357 5.0E-88 T 09-03-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 ARZXY2_RS01115 7057faaec5a1cd0ff9c37f297c395ae1 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 124 5.4E-8 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS01115 7057faaec5a1cd0ff9c37f297c395ae1 260 SUPERFAMILY SSF54593 144 254 5.64E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01115 7057faaec5a1cd0ff9c37f297c395ae1 260 Gene3D G3DSA:3.10.180.10 144 256 2.0E-27 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01115 7057faaec5a1cd0ff9c37f297c395ae1 260 Gene3D G3DSA:3.10.180.10 11 130 1.2E-34 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01115 7057faaec5a1cd0ff9c37f297c395ae1 260 SUPERFAMILY SSF54593 13 131 6.98E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS18300 4a2b69f889372d820ede83b9882fb93f 273 Gene3D G3DSA:3.40.50.1820 5 270 7.9E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS18300 4a2b69f889372d820ede83b9882fb93f 273 Pfam PF07859 alpha/beta hydrolase fold 40 248 1.3E-7 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 ARZXY2_RS18300 4a2b69f889372d820ede83b9882fb93f 273 SUPERFAMILY SSF53474 4 268 2.04E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09260 4f7d78e8f0a42bc5b7a236f8b31ad92b 206 Pfam PF01300 Telomere recombination 23 198 8.0E-42 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 ARZXY2_RS09260 4f7d78e8f0a42bc5b7a236f8b31ad92b 206 Gene3D G3DSA:3.90.870.10 2 204 2.8E-58 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS09260 4f7d78e8f0a42bc5b7a236f8b31ad92b 206 SUPERFAMILY SSF55821 1 204 1.92E-58 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS09260 4f7d78e8f0a42bc5b7a236f8b31ad92b 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 200 2.1E-54 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:1.20.1060.10 492 610 3.4E-28 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 TIGRFAM TIGR00593 pola: DNA polymerase I 1 876 1.5E-271 T 09-03-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 672 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 692 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 740 751 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 626 641 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 824 837 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 810 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 603 625 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 728 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 762 773 1.0E-68 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SMART SM00279 164 199 7.0E-10 T 09-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SUPERFAMILY SSF56672 474 876 4.23E-132 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SMART SM00475 1 252 9.5E-98 T 09-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SMART SM00474 296 467 0.0025 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SUPERFAMILY SSF88723 2 144 6.38E-45 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Pfam PF00476 DNA polymerase family A 500 875 7.8E-135 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SMART SM00482 634 841 3.7E-101 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:1.10.150.20 178 236 6.7E-22 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:3.30.70.370 611 660 1.5E-62 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:3.30.70.370 768 876 1.5E-62 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 162 255 5.4E-24 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SUPERFAMILY SSF53098 330 468 1.82E-23 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:3.30.420.10 309 490 2.3E-41 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 160 1.2E-45 T 09-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:1.10.150.20 661 767 9.1E-27 T 09-03-2017 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 SUPERFAMILY SSF47807 162 275 1.17E-28 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ARZXY2_RS09185 2fd6e5751666adb52cd3606d4e009215 878 Gene3D G3DSA:3.40.50.1010 1 177 1.1E-56 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 121 273 2.6E-21 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 Gene3D G3DSA:1.10.520.20 121 202 2.4E-5 T 09-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 Hamap MF_01416 ATP synthase subunit delta [atpD]. 92 275 14.493 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 235 254 - T 09-03-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 Pfam PF00213 ATP synthase delta (OSCP) subunit 121 273 5.7E-30 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 PRINTS PR00125 ATP synthase delta subunit signature 96 115 4.0E-10 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 PRINTS PR00125 ATP synthase delta subunit signature 233 248 4.0E-10 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS05245 2511f5e2cc447f2f812cd8367e7d235f 275 PRINTS PR00125 ATP synthase delta subunit signature 248 266 4.0E-10 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 ARZXY2_RS14385 92fcbee226711bdb3c0cede32e269ab4 470 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 467 2.1E-196 T 09-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS14385 92fcbee226711bdb3c0cede32e269ab4 470 Pfam PF03313 Serine dehydratase alpha chain 193 464 4.8E-102 T 09-03-2017 IPR005130 Serine dehydratase-like, alpha subunit ARZXY2_RS14385 92fcbee226711bdb3c0cede32e269ab4 470 Pfam PF03315 Serine dehydratase beta chain 5 160 4.2E-52 T 09-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS14385 92fcbee226711bdb3c0cede32e269ab4 470 SUPERFAMILY SSF143548 17 161 7.59E-39 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS14385 92fcbee226711bdb3c0cede32e269ab4 470 Gene3D G3DSA:3.30.1330.90 11 162 1.9E-49 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 Gene3D G3DSA:3.40.50.300 21 252 3.4E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 Gene3D G3DSA:3.40.50.300 263 409 3.6E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 SMART SM00487 56 266 3.9E-53 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 SUPERFAMILY SSF52540 116 401 2.18E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 Pfam PF00270 DEAD/DEAH box helicase 61 232 9.3E-48 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 SMART SM00490 302 383 1.3E-29 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 194 202 - T 09-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site ARZXY2_RS04395 be589eb602d2b0c7510cf26d8f0c9904 559 Pfam PF00271 Helicase conserved C-terminal domain 275 383 2.6E-28 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS02440 e9943b7c9fe5bdd919e40f3498e11b1c 175 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 46 2.0E-8 T 09-03-2017 IPR023833 Signal peptide, camelysin ARZXY2_RS02440 e9943b7c9fe5bdd919e40f3498e11b1c 175 TIGRFAM TIGR04089 exp_by_SipW_III: alternate signal-mediated exported protein, RER_14450 family 3 168 2.0E-36 T 09-03-2017 IPR024006 Conserved hypothetical protein CHP04089 ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 13 367 42.951 T 09-03-2017 IPR024892 Putative phenylalanine aminotransferase ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 366 46.312 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 Gene3D G3DSA:3.40.640.10 51 263 1.6E-63 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 Pfam PF00155 Aminotransferase class I and II 39 337 5.5E-50 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 Gene3D G3DSA:3.90.1150.10 264 362 4.9E-25 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS20005 b1f72e062b98df3e1a901cecef64cb62 372 SUPERFAMILY SSF53383 31 360 6.95E-71 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 236 5.9E-8 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 Gene3D G3DSA:3.30.360.10 136 347 1.7E-28 T 09-03-2017 ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 126 1.4E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 SUPERFAMILY SSF55347 136 266 1.1E-22 T 09-03-2017 ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 SUPERFAMILY SSF51735 2 160 1.07E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20120 d3f4008cc5739ae47dfbd55b68f5b1dc 349 Gene3D G3DSA:3.40.50.720 3 135 7.1E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18710 9e1762a617e2692e73e2abeea7375357 399 Pfam PF07690 Major Facilitator Superfamily 245 396 1.4E-14 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS18710 9e1762a617e2692e73e2abeea7375357 399 Gene3D G3DSA:1.20.1250.20 211 390 4.8E-23 T 09-03-2017 ARZXY2_RS18710 9e1762a617e2692e73e2abeea7375357 399 SUPERFAMILY SSF103473 15 394 4.58E-43 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18710 9e1762a617e2692e73e2abeea7375357 399 Gene3D G3DSA:1.20.1250.20 16 189 2.4E-12 T 09-03-2017 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 Gene3D G3DSA:3.40.190.10 185 237 1.4E-11 T 09-03-2017 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 Gene3D G3DSA:3.40.190.10 86 184 2.2E-17 T 09-03-2017 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 SUPERFAMILY SSF46785 2 110 1.04E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.2E-19 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 Pfam PF03466 LysR substrate binding domain 88 266 1.2E-30 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 SUPERFAMILY SSF53850 88 274 5.43E-29 T 09-03-2017 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.7E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.7E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS00295 d730a81d9065b84e1d3b6ba018b6a282 284 Gene3D G3DSA:1.10.10.10 6 83 4.3E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18240 9b16e7d261405d87f4eabdf0f872cb5f 183 Pfam PF01872 RibD C-terminal domain 2 173 6.8E-19 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS18240 9b16e7d261405d87f4eabdf0f872cb5f 183 Gene3D G3DSA:3.40.430.10 3 180 2.2E-24 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS18240 9b16e7d261405d87f4eabdf0f872cb5f 183 SUPERFAMILY SSF53597 2 180 3.14E-25 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 229 6.5E-22 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Gene3D G3DSA:1.10.540.10 9 120 1.4E-19 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Gene3D G3DSA:2.40.110.10 128 227 5.5E-29 T 09-03-2017 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 120 9.2E-15 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Gene3D G3DSA:1.20.140.10 228 401 1.9E-33 T 09-03-2017 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 SUPERFAMILY SSF47203 246 401 3.06E-33 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 SUPERFAMILY SSF56645 9 236 4.71E-54 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS15420 4aecad35cd9744a598e4ccb56ca233e2 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 398 4.7E-20 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS20520 ac16ee24cd5bf502cc1f36885d095e8b 344 SUPERFAMILY SSF51430 6 319 1.3E-92 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS20520 ac16ee24cd5bf502cc1f36885d095e8b 344 Gene3D G3DSA:3.20.20.100 6 318 1.5E-89 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS20520 ac16ee24cd5bf502cc1f36885d095e8b 344 Pfam PF00248 Aldo/keto reductase family 18 318 1.2E-70 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS02560 caf84d0777cbab0eaf82d7dc72eb0296 463 Pfam PF02706 Chain length determinant protein 1 134 4.1E-16 T 09-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 ARZXY2_RS02560 caf84d0777cbab0eaf82d7dc72eb0296 463 SUPERFAMILY SSF52540 262 441 5.7E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02560 caf84d0777cbab0eaf82d7dc72eb0296 463 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 243 447 2.3E-57 T 09-03-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 ARZXY2_RS02560 caf84d0777cbab0eaf82d7dc72eb0296 463 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 272 442 1.5E-14 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain ARZXY2_RS02560 caf84d0777cbab0eaf82d7dc72eb0296 463 Gene3D G3DSA:3.40.50.300 262 438 2.1E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13345 71660c8e2494a98b9f29b0ec4899237c 423 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 378 1.6E-40 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS01595 b5d26f2abf3e4033f24f1937d5fcb7b5 309 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 27 111 4.1E-15 T 09-03-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin ARZXY2_RS01595 b5d26f2abf3e4033f24f1937d5fcb7b5 309 SUPERFAMILY SSF52980 193 299 1.61E-5 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 Gene3D G3DSA:1.20.1250.20 270 465 6.3E-19 T 09-03-2017 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 Gene3D G3DSA:1.20.1250.20 15 198 2.7E-30 T 09-03-2017 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 1.2E-5 T 09-03-2017 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 404 423 1.2E-5 T 09-03-2017 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 1.2E-5 T 09-03-2017 ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 SUPERFAMILY SSF103473 252 467 3.92E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 SUPERFAMILY SSF103473 11 203 3.92E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16125 7fd286538824392be4fc32d49897f63e 484 Pfam PF07690 Major Facilitator Superfamily 22 413 1.9E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 25 642 6.8E-223 T 09-03-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 SUPERFAMILY SSF52467 204 386 1.7E-36 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 239 371 3.3E-26 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 SUPERFAMILY SSF52518 412 625 1.33E-37 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Gene3D G3DSA:3.40.50.970 20 230 5.2E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Gene3D G3DSA:3.40.50.970 424 606 1.3E-36 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 SUPERFAMILY SSF52518 24 229 5.43E-32 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 446 598 2.0E-26 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 26 215 6.7E-32 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS09740 516395f9bda15cc279c4628a032e0c3b 653 Gene3D G3DSA:3.40.50.1220 233 423 2.9E-41 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS05210 c70997b391a330f2b398b2069150de13 321 Gene3D G3DSA:3.90.550.10 8 223 2.9E-25 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS05210 c70997b391a330f2b398b2069150de13 321 Pfam PF00535 Glycosyl transferase family 2 8 138 2.2E-17 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS05210 c70997b391a330f2b398b2069150de13 321 SUPERFAMILY SSF53448 2 210 2.44E-28 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:3.30.470.30 151 283 2.2E-50 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SUPERFAMILY SSF50249 348 430 6.34E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SUPERFAMILY SSF56091 30 347 8.28E-113 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 353 429 1.6E-28 T 09-03-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:1.10.150.20 470 532 8.6E-9 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Pfam PF12826 Helix-hairpin-helix motif 580 643 2.0E-21 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:1.10.150.20 574 654 5.6E-28 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:1.10.287.610 29 95 2.2E-26 T 09-03-2017 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 441 468 9.9E-8 T 09-03-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 147 176 - T 09-03-2017 IPR018239 NAD-dependent DNA ligase, active site ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SUPERFAMILY SSF47781 561 654 5.72E-45 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SUPERFAMILY SSF47781 437 530 5.72E-45 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 39 531 1.9E-171 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 663 736 1.3E-12 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 362 377 - T 09-03-2017 IPR033136 NAD-dependent DNA ligase, conserved site ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:3.40.50.10190 662 744 3.7E-24 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SUPERFAMILY SSF52113 664 744 2.06E-18 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SMART SM00292 662 739 1.7E-13 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 SMART SM00532 31 483 4.8E-250 T 09-03-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Gene3D G3DSA:2.40.50.140 351 421 6.8E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 PIRSF PIRSF001604 26 740 2.5E-227 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 32 349 7.9E-120 T 09-03-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 ARZXY2_RS12395 4b0c81bb5eb50e5e7b5243a7e378817d 767 Hamap MF_01588 DNA ligase [ligA]. 30 736 49.746 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 ARZXY2_RS20240 1674389ba0545132f1ce398004f6e971 121 Pfam PF06304 Protein of unknown function (DUF1048) 12 113 6.5E-31 T 09-03-2017 IPR008316 Uncharacterised conserved protein UCP029876 ARZXY2_RS20240 1674389ba0545132f1ce398004f6e971 121 Gene3D G3DSA:1.10.1900.10 17 102 4.5E-25 T 09-03-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 ARZXY2_RS20240 1674389ba0545132f1ce398004f6e971 121 SUPERFAMILY SSF158560 4 112 4.05E-28 T 09-03-2017 ARZXY2_RS12645 4ed520c68bbdad1f0547d7ae433482d9 307 Pfam PF06314 Acetoacetate decarboxylase (ADC) 26 162 2.5E-18 T 09-03-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 ARZXY2_RS12645 4ed520c68bbdad1f0547d7ae433482d9 307 SUPERFAMILY SSF160104 24 172 1.24E-19 T 09-03-2017 ARZXY2_RS12645 4ed520c68bbdad1f0547d7ae433482d9 307 Gene3D G3DSA:2.40.400.10 26 161 7.9E-14 T 09-03-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 Gene3D G3DSA:3.40.50.1000 54 129 1.3E-24 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 Gene3D G3DSA:3.40.50.1000 203 285 1.3E-24 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 SUPERFAMILY SSF48208 491 868 8.08E-90 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 Gene3D G3DSA:1.50.10.10 505 869 8.3E-78 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 SUPERFAMILY SSF56784 54 280 7.27E-21 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 Pfam PF02358 Trehalose-phosphatase 59 246 5.9E-12 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 ARZXY2_RS00170 b0bdc344213624b9a6f9363c2ade1d61 878 Pfam PF00723 Glycosyl hydrolases family 15 504 865 1.7E-33 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 ARZXY2_RS19920 2e43fa8018d1d7c808355c71ca74174b 402 Pfam PF00155 Aminotransferase class I and II 34 394 4.6E-69 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS19920 2e43fa8018d1d7c808355c71ca74174b 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 238 251 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ARZXY2_RS19920 2e43fa8018d1d7c808355c71ca74174b 402 Gene3D G3DSA:3.90.1150.10 278 401 3.8E-39 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS19920 2e43fa8018d1d7c808355c71ca74174b 402 Gene3D G3DSA:3.40.640.10 47 277 1.4E-68 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS19920 2e43fa8018d1d7c808355c71ca74174b 402 SUPERFAMILY SSF53383 6 399 5.91E-105 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS16195 e4d76d075ef11cff80f753b1f901bdbd 190 Gene3D G3DSA:3.40.50.2020 9 184 5.3E-46 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS16195 e4d76d075ef11cff80f753b1f901bdbd 190 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 21 179 2.7E-36 T 09-03-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS16195 e4d76d075ef11cff80f753b1f901bdbd 190 SUPERFAMILY SSF53271 11 186 1.97E-32 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS16195 e4d76d075ef11cff80f753b1f901bdbd 190 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 190 24.377 T 09-03-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 ARZXY2_RS16195 e4d76d075ef11cff80f753b1f901bdbd 190 Pfam PF00156 Phosphoribosyl transferase domain 101 169 3.4E-8 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 SUPERFAMILY SSF52821 370 459 3.54E-17 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 SUPERFAMILY SSF56281 1 244 3.08E-35 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 Gene3D G3DSA:3.40.250.10 378 460 2.8E-15 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 SMART SM00450 363 457 6.6E-9 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 Gene3D G3DSA:3.60.15.10 9 237 1.3E-41 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 SMART SM00849 12 181 3.1E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 Pfam PF00581 Rhodanese-like domain 375 445 4.2E-6 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02925 a859072a01c198e6c6b921a98e1a98fd 464 SUPERFAMILY SSF52821 223 334 2.1E-6 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS05830 b39223c98065895867feaefbaedfb34e 67 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 65 12.008 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS05830 b39223c98065895867feaefbaedfb34e 67 Pfam PF01783 Ribosomal L32p protein family 2 44 2.1E-13 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS05830 b39223c98065895867feaefbaedfb34e 67 SUPERFAMILY SSF57829 2 38 2.08E-9 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 ARZXY2_RS05830 b39223c98065895867feaefbaedfb34e 67 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 44 4.2E-11 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 1.3E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 58 67 1.3E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 1.3E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Gene3D G3DSA:3.40.50.620 220 401 5.8E-57 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Gene3D G3DSA:3.40.50.880 8 219 7.1E-60 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Gene3D G3DSA:3.30.300.10 404 529 1.7E-48 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 SUPERFAMILY SSF52317 12 234 2.29E-55 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Pfam PF00958 GMP synthase C terminal domain 437 528 3.0E-38 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Pfam PF00117 Glutamine amidotransferase class-I 16 197 7.9E-41 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 SUPERFAMILY SSF52402 190 449 3.31E-54 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 529 3.4E-144 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 85 101 8.5E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 55 69 8.5E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 14 28 8.5E-6 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00097 Anthranilate synthase component II signature 58 67 7.0E-5 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00097 Anthranilate synthase component II signature 85 96 7.0E-5 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 PRINTS PR00097 Anthranilate synthase component II signature 174 187 7.0E-5 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 11 529 53.785 T 09-03-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 Pfam PF02540 NAD synthase 215 251 5.3E-7 T 09-03-2017 IPR022310 NAD/GMP synthase ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 SUPERFAMILY SSF54810 408 529 8.5E-47 T 09-03-2017 ARZXY2_RS03945 6a67071298dec9eb486335b297b2dbd7 529 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 14 196 8.9E-73 T 09-03-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 ARZXY2_RS15940 6be666bd3a86f2ba2f5f1aaa24dd4f34 106 Gene3D G3DSA:3.30.70.900 1 88 2.0E-25 T 09-03-2017 ARZXY2_RS15940 6be666bd3a86f2ba2f5f1aaa24dd4f34 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 5.1E-20 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain ARZXY2_RS15940 6be666bd3a86f2ba2f5f1aaa24dd4f34 106 SUPERFAMILY SSF54909 1 94 5.07E-28 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 Gene3D G3DSA:1.10.150.20 166 238 4.5E-18 T 09-03-2017 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 SUPERFAMILY SSF56672 6 236 9.78E-63 T 09-03-2017 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 SUPERFAMILY SSF100879 245 347 1.26E-19 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 Gene3D G3DSA:3.30.70.270 72 163 2.2E-16 T 09-03-2017 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 Pfam PF11799 impB/mucB/samB family C-terminal domain 247 342 3.5E-6 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 Pfam PF00817 impB/mucB/samB family 10 154 7.1E-33 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS00530 4c20a47192f5eb316f7fd5026ce998c4 357 Gene3D G3DSA:3.30.1490.100 247 342 7.3E-16 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 62 6.6E-9 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 184 1.4E-54 T 09-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 185 27.204 T 09-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 Pfam PF01467 Cytidylyltransferase-like 2 159 3.6E-30 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 Gene3D G3DSA:3.40.50.620 1 186 9.2E-65 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07700 e7abd0a520f171d52061b45a12074dcd 207 SUPERFAMILY SSF52374 1 187 1.34E-51 T 09-03-2017 ARZXY2_RS00300 116a254a5dac875b002447ff9538e1ce 471 Gene3D G3DSA:1.20.1250.20 268 446 1.3E-12 T 09-03-2017 ARZXY2_RS00300 116a254a5dac875b002447ff9538e1ce 471 Gene3D G3DSA:1.20.1250.20 61 246 2.1E-20 T 09-03-2017 ARZXY2_RS00300 116a254a5dac875b002447ff9538e1ce 471 Pfam PF05977 Transmembrane secretion effector 54 442 5.9E-45 T 09-03-2017 IPR010290 Transmembrane secretion effector ARZXY2_RS00300 116a254a5dac875b002447ff9538e1ce 471 SUPERFAMILY SSF103473 62 446 1.7E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 91 254 2.1E-27 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 259 465 1.0E-48 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 294 316 5.3E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 351 365 5.3E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 366 380 5.3E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 433 446 5.3E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 124 143 5.3E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 SUPERFAMILY SSF56601 101 479 7.79E-65 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 Gene3D G3DSA:3.40.710.10 256 480 1.2E-53 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 Gene3D G3DSA:3.40.710.10 106 180 1.2E-8 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS18020 4331b0063c993fce82b37a0b467c4128 481 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 259 456 8.4E-39 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 Gene3D G3DSA:3.30.70.920 75 160 2.5E-19 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 SUPERFAMILY SSF46785 18 77 1.85E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 SUPERFAMILY SSF54909 80 161 4.83E-15 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 Pfam PF01037 Lrp/AsnC ligand binding domain 84 157 5.4E-15 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 SMART SM00344 18 127 4.0E-34 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 2.5E-13 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 Gene3D G3DSA:1.10.10.10 17 69 4.5E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04050 b20b7b60d87450580324d75a71f60260 168 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 65 1.1E-13 T 09-03-2017 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 1.4E-23 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 SMART SM00649 11 142 5.1E-82 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 SUPERFAMILY SSF46906 69 142 3.14E-25 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 SUPERFAMILY SSF54747 4 74 1.57E-29 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 142 29.62 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 09-03-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 Gene3D G3DSA:1.10.10.250 74 142 7.7E-30 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 Gene3D G3DSA:3.30.1550.10 4 73 4.3E-38 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 1.7E-28 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 8.2E-62 T 09-03-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03410 64f3eba576b565d325136542e11c15f4 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 75 3.0E-16 T 09-03-2017 ARZXY2_RS10505 d8188922b15c935a3e11244491400ca8 189 Gene3D G3DSA:2.40.380.10 11 172 1.6E-14 T 09-03-2017 IPR007295 Domain of unknown function DUF402 ARZXY2_RS10505 d8188922b15c935a3e11244491400ca8 189 SUPERFAMILY SSF159234 10 172 6.28E-12 T 09-03-2017 ARZXY2_RS10505 d8188922b15c935a3e11244491400ca8 189 Pfam PF04167 Protein of unknown function (DUF402) 66 136 6.2E-9 T 09-03-2017 IPR007295 Domain of unknown function DUF402 ARZXY2_RS20325 0ddf6db2783055e0505ba26d469a8427 513 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 31 466 9.5E-39 T 09-03-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 ARZXY2_RS20325 0ddf6db2783055e0505ba26d469a8427 513 PIRSF PIRSF002744 2 492 1.2E-127 T 09-03-2017 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PIRSF PIRSF036480 17 299 1.0E-107 T 09-03-2017 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 Gene3D G3DSA:3.30.70.260 19 98 5.4E-25 T 09-03-2017 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 Gene3D G3DSA:3.40.50.170 104 298 3.0E-56 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 Pfam PF00551 Formyl transferase 104 280 7.7E-39 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 SUPERFAMILY SSF55021 20 100 6.25E-16 T 09-03-2017 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 104 126 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 54 66 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 272 297 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 126 153 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 250 272 1.1E-52 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 SUPERFAMILY SSF53328 104 298 9.94E-63 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 298 1.1E-97 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS20335 629eebb4c5da1ace627ac6d259d58d65 299 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 298 45.53 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS08865 8eda9815d03767c132bd72f6c0bec86c 518 SUPERFAMILY SSF56059 58 218 1.57E-51 T 09-03-2017 ARZXY2_RS08865 8eda9815d03767c132bd72f6c0bec86c 518 SUPERFAMILY SSF56059 325 471 1.57E-51 T 09-03-2017 ARZXY2_RS08865 8eda9815d03767c132bd72f6c0bec86c 518 Pfam PF14403 Circularly permuted ATP-grasp type 2 80 456 6.1E-160 T 09-03-2017 IPR025841 Circularly permuted ATP-grasp type 2 ARZXY2_RS08865 8eda9815d03767c132bd72f6c0bec86c 518 PIRSF PIRSF005522 3 483 7.5E-209 T 09-03-2017 IPR016450 Uncharacterised conserved protein UCP005522 ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 Pfam PF08279 HTH domain 164 209 1.3E-5 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 SMART SM00448 2 115 3.0E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 SUPERFAMILY SSF52172 2 133 1.71E-34 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 SUPERFAMILY SSF46785 161 205 1.12E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 PIRSF PIRSF006171 1 222 1.1E-75 T 09-03-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 Gene3D G3DSA:1.10.10.10 164 220 1.8E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 Pfam PF00072 Response regulator receiver domain 4 115 4.4E-24 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS15660 6c505096062375386f339d653f245e51 222 Gene3D G3DSA:3.40.50.2300 2 127 3.0E-31 T 09-03-2017 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 Pfam PF01960 ArgJ family 11 388 2.4E-130 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 Gene3D G3DSA:3.60.70.12 3 264 3.2E-95 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 SUPERFAMILY SSF56266 6 384 2.62E-126 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 387 1.5E-107 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 388 134.225 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS11225 67d72fc018de417f9fe41d32dfb51b38 388 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 386 0.0 T 09-03-2017 ARZXY2_RS00615 e63f1dc55d81391fc96c785707733d6f 408 SUPERFAMILY SSF53383 4 400 6.25E-92 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS00615 e63f1dc55d81391fc96c785707733d6f 408 Gene3D G3DSA:3.90.1150.10 246 403 4.8E-45 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS00615 e63f1dc55d81391fc96c785707733d6f 408 Gene3D G3DSA:3.40.640.10 51 245 1.2E-59 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS00615 e63f1dc55d81391fc96c785707733d6f 408 Pfam PF00155 Aminotransferase class I and II 52 395 2.0E-48 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Gene3D G3DSA:2.60.120.260 330 460 3.9E-12 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 SUPERFAMILY SSF102588 65 258 5.36E-8 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Gene3D G3DSA:3.40.50.10320 65 255 1.5E-6 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 474 539 2.4E-21 T 09-03-2017 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 557 624 3.8E-16 T 09-03-2017 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF13287 Fn3 associated 653 715 8.7E-13 T 09-03-2017 IPR026876 Fn3 associated repeat ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF02585 GlcNAc-PI de-N-acetylase 66 248 1.2E-10 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 SUPERFAMILY SSF49785 331 460 1.11E-10 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 SUPERFAMILY SSF69318 719 968 6.63E-37 T 09-03-2017 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 878 939 1.6E-6 T 09-03-2017 ARZXY2_RS14025 7b12ac9cc5d8465f76c755fa52bb2a87 976 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 727 789 3.5E-8 T 09-03-2017 ARZXY2_RS16995 c2224b8e9e6910bbd21020c7b58171a5 349 SUPERFAMILY SSF56281 6 326 6.42E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS16995 c2224b8e9e6910bbd21020c7b58171a5 349 Pfam PF00753 Metallo-beta-lactamase superfamily 30 241 6.5E-20 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS16995 c2224b8e9e6910bbd21020c7b58171a5 349 SMART SM00849 29 241 1.2E-21 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS16995 c2224b8e9e6910bbd21020c7b58171a5 349 Gene3D G3DSA:3.60.15.10 11 284 5.6E-37 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS16010 de07ba055420deaae9402f63c86be496 481 SMART SM00640 7 434 3.7E-9 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS16010 de07ba055420deaae9402f63c86be496 481 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 7 290 1.2E-27 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS16010 de07ba055420deaae9402f63c86be496 481 Gene3D G3DSA:2.60.120.560 349 475 1.1E-4 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS16010 de07ba055420deaae9402f63c86be496 481 Gene3D G3DSA:2.115.10.20 13 292 2.7E-19 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS16010 de07ba055420deaae9402f63c86be496 481 SUPERFAMILY SSF75005 5 291 2.86E-57 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS18015 a8336a687ce154f39e81283e6ff3ce03 373 SUPERFAMILY SSF55486 15 371 3.22E-98 T 09-03-2017 ARZXY2_RS18015 a8336a687ce154f39e81283e6ff3ce03 373 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 16 371 1.1E-127 T 09-03-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated ARZXY2_RS18015 a8336a687ce154f39e81283e6ff3ce03 373 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 16 371 2.7E-118 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 ARZXY2_RS18015 a8336a687ce154f39e81283e6ff3ce03 373 Pfam PF10103 Zinicin-like metallopeptidase 16 368 5.0E-110 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 Gene3D G3DSA:3.40.50.2300 70 179 2.3E-15 T 09-03-2017 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 Pfam PF13377 Periplasmic binding protein-like domain 179 339 2.4E-43 T 09-03-2017 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 SUPERFAMILY SSF53822 68 343 7.24E-70 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 54 5.5E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 SUPERFAMILY SSF47413 9 63 2.3E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 Gene3D G3DSA:1.10.260.40 9 54 1.2E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 Gene3D G3DSA:3.40.50.2300 180 340 1.1E-59 T 09-03-2017 ARZXY2_RS11635 029a6518ec7a089d445c9721357f92d9 361 SMART SM00354 9 77 3.7E-9 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Gene3D G3DSA:2.70.20.10 346 493 5.3E-34 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Gene3D G3DSA:2.70.20.10 202 341 1.2E-29 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 SUPERFAMILY SSF56712 9 588 1.44E-181 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Hamap MF_00952 DNA topoisomerase 1 [topA]. 9 782 51.775 T 09-03-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 319 328 6.4E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 180 198 6.4E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 6.4E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 398 414 6.4E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 510 524 6.4E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Gene3D G3DSA:3.40.50.140 8 152 4.7E-48 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 SMART SM00493 9 122 2.4E-33 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF01751 Toprim domain 11 131 1.7E-28 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 314 328 - T 09-03-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF13368 Topoisomerase C-terminal repeat 836 888 2.1E-17 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF13368 Topoisomerase C-terminal repeat 773 824 2.1E-15 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF13368 Topoisomerase C-terminal repeat 685 769 1.9E-11 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF13368 Topoisomerase C-terminal repeat 621 676 6.0E-5 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 SMART SM00437 277 547 9.6E-112 T 09-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Gene3D G3DSA:1.10.460.10 153 200 8.7E-51 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Gene3D G3DSA:1.10.460.10 494 588 8.7E-51 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 11 635 3.2E-233 T 09-03-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 Pfam PF01131 DNA topoisomerase 146 583 1.8E-120 T 09-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS01895 de93eb1b23e2b921002ccd95d1b52778 906 SMART SM00436 122 210 4.5E-45 T 09-03-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 Gene3D G3DSA:1.20.1560.10 53 348 4.9E-12 T 09-03-2017 ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 SUPERFAMILY SSF90123 42 340 9.29E-20 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 SMART SM00382 399 595 4.5E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 Pfam PF00005 ABC transporter 391 550 2.2E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 ProSitePatterns PS00211 ABC transporters family signature. 522 536 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 Gene3D G3DSA:3.40.50.300 372 614 1.7E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03900 f2eb3c96769951d5f5ad0d4006a993b2 632 SUPERFAMILY SSF52540 365 619 1.07E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 SUPERFAMILY SSF48452 157 286 4.93E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 SMART SM00530 8 62 2.9E-11 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 Gene3D G3DSA:1.25.40.10 314 390 3.2E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 Gene3D G3DSA:1.25.40.10 68 270 3.2E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 Gene3D G3DSA:1.10.260.40 5 62 1.7E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 Pfam PF13560 Helix-turn-helix domain 5 64 3.1E-11 T 09-03-2017 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 SUPERFAMILY SSF47413 5 62 4.22E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01685 c5f90d9d9c09c29b16450ee385c2b33b 422 SUPERFAMILY SSF48452 242 379 1.32E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 Gene3D G3DSA:3.40.50.300 1 213 7.2E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 Gene3D G3DSA:3.40.50.300 441 521 1.3E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 SUPERFAMILY SSF52540 326 517 3.83E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 SUPERFAMILY SSF52540 1 199 3.83E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 PIRSF PIRSF003128 1 575 4.4E-152 T 09-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 570 2.1E-160 T 09-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 ARZXY2_RS11120 d88541413d744a89696f7f1a9aef5384 579 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 518 8.8E-16 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 SUPERFAMILY SSF51905 274 369 1.28E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 SUPERFAMILY SSF51905 8 177 1.28E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 Gene3D G3DSA:3.50.50.60 274 359 8.0E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 Gene3D G3DSA:3.50.50.60 8 182 8.0E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 Pfam PF01494 FAD binding domain 8 318 1.9E-20 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 SUPERFAMILY SSF54373 182 279 8.44E-9 T 09-03-2017 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.5E-14 T 09-03-2017 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.5E-14 T 09-03-2017 ARZXY2_RS17025 010246cb84b99e0203539e0ffcc682cb 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.5E-14 T 09-03-2017 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 SUPERFAMILY SSF51430 3 268 1.44E-86 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 Gene3D G3DSA:3.20.20.100 2 268 9.9E-95 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 Pfam PF00248 Aldo/keto reductase family 21 260 2.7E-47 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.3E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 PRINTS PR00069 Aldo-keto reductase signature 34 58 4.3E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.3E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.3E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 PRINTS PR00069 Aldo-keto reductase signature 94 112 4.3E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17910 31ee246042c392c162a8c4429b0c0789 285 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 Pfam PF16884 N-terminal domain of oxidoreductase 12 117 2.3E-40 T 09-03-2017 ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 SUPERFAMILY SSF50129 291 339 4.57E-5 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 SMART SM00829 22 338 7.4E-8 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 Pfam PF00107 Zinc-binding dehydrogenase 164 294 1.0E-29 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 SUPERFAMILY SSF50129 10 147 2.25E-38 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 SUPERFAMILY SSF51735 128 305 3.4E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 Gene3D G3DSA:3.90.180.10 7 146 3.7E-51 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS13180 17e83bc17504cd25c0cdfb2a868f5817 340 Gene3D G3DSA:3.40.50.720 147 307 2.4E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19840 70a3de603a430600166fccfe3b0dc5ad 428 Pfam PF01547 Bacterial extracellular solute-binding protein 60 338 7.6E-28 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS19840 70a3de603a430600166fccfe3b0dc5ad 428 Gene3D G3DSA:3.40.190.10 154 358 2.3E-39 T 09-03-2017 ARZXY2_RS19840 70a3de603a430600166fccfe3b0dc5ad 428 Gene3D G3DSA:3.40.190.10 11 147 6.8E-17 T 09-03-2017 ARZXY2_RS19840 70a3de603a430600166fccfe3b0dc5ad 428 SUPERFAMILY SSF53850 25 427 2.99E-54 T 09-03-2017 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 Pfam PF01546 Peptidase family M20/M25/M40 74 358 3.4E-20 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 Gene3D G3DSA:3.40.630.10 300 376 1.1E-55 T 09-03-2017 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 Gene3D G3DSA:3.40.630.10 3 180 1.1E-55 T 09-03-2017 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 Pfam PF07687 Peptidase dimerisation domain 187 283 4.1E-11 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 PIRSF PIRSF005962 5 376 2.5E-83 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 SUPERFAMILY SSF53187 9 199 1.19E-47 T 09-03-2017 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 SUPERFAMILY SSF53187 300 375 1.19E-47 T 09-03-2017 ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 SUPERFAMILY SSF55031 185 292 2.09E-29 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 Gene3D G3DSA:3.30.70.360 183 299 4.6E-38 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS16395 c8c078b19ff7116e440dc00e21a7de52 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 359 1.9E-78 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Gene3D G3DSA:3.40.47.10 308 444 2.2E-38 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Gene3D G3DSA:3.40.47.10 182 225 2.2E-38 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Pfam PF00108 Thiolase, N-terminal domain 21 290 6.2E-49 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Pfam PF02803 Thiolase, C-terminal domain 317 444 4.8E-26 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Gene3D G3DSA:3.40.47.10 20 139 1.0E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 Gene3D G3DSA:3.40.47.10 226 302 1.0E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 SUPERFAMILY SSF53901 296 444 7.53E-27 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 22 444 3.2E-111 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 SUPERFAMILY SSF53901 20 297 2.76E-54 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08825 578207f99c32f0224b3d47dd2fbfcecc 446 PIRSF PIRSF000429 15 446 1.1E-100 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 SUPERFAMILY SSF49503 52 182 2.6E-33 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Gene3D G3DSA:2.60.40.420 50 177 3.8E-33 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Pfam PF07732 Multicopper oxidase 70 178 2.9E-27 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 SUPERFAMILY SSF49503 362 491 4.49E-27 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Gene3D G3DSA:2.60.40.420 357 492 2.9E-34 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Gene3D G3DSA:2.60.40.420 178 316 7.4E-26 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Pfam PF07731 Multicopper oxidase 389 492 4.3E-25 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 SUPERFAMILY SSF49503 184 314 6.29E-19 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 Pfam PF00394 Multicopper oxidase 213 294 4.2E-4 T 09-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 ARZXY2_RS06020 c30a00f5cf3f9789aec2c3e2ae9ac78b 494 ProSitePatterns PS00080 Multicopper oxidases signature 2. 476 487 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 ARZXY2_RS00415 9260a22b9d124c8af1dec2d9a86bfba8 200 Pfam PF13523 Acetyltransferase (GNAT) domain 32 174 1.3E-45 T 09-03-2017 ARZXY2_RS00415 9260a22b9d124c8af1dec2d9a86bfba8 200 Gene3D G3DSA:3.40.630.30 24 192 1.2E-45 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS00415 9260a22b9d124c8af1dec2d9a86bfba8 200 SUPERFAMILY SSF55729 24 187 1.12E-36 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS00415 9260a22b9d124c8af1dec2d9a86bfba8 200 SMART SM01006 28 76 1.5E-13 T 09-03-2017 IPR019432 Siderophore biosynthesis protein, conserved domain ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 SMART SM00345 7 66 3.9E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.8E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.8E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 SUPERFAMILY SSF48008 89 221 1.94E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 Gene3D G3DSA:1.20.120.530 88 222 1.5E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 SMART SM00895 92 214 6.8E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 Pfam PF07729 FCD domain 92 213 1.6E-25 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 Gene3D G3DSA:1.10.10.10 4 70 4.0E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 6.7E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS20445 b9c3e590c461039e1ebb09920e237aea 223 SUPERFAMILY SSF46785 4 70 4.05E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 PIRSF PIRSF000089 1 317 9.3E-84 T 09-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 SUPERFAMILY SSF52402 3 172 1.05E-31 T 09-03-2017 ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 Gene3D G3DSA:3.40.50.620 1 176 1.8E-29 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 Pfam PF01012 Electron transfer flavoprotein domain 5 173 7.5E-27 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 Gene3D G3DSA:3.40.50.1220 190 313 2.0E-50 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 SMART SM00893 4 186 3.0E-17 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 275 2.0E-30 T 09-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 ARZXY2_RS04615 78946118862bdb82f61c6bd540629336 317 SUPERFAMILY SSF52467 194 311 7.63E-41 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 SMART SM00650 45 218 1.3E-62 T 09-03-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 Gene3D G3DSA:3.40.50.150 17 219 8.4E-63 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 61 88 - T 09-03-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 Gene3D G3DSA:1.10.8.100 224 287 1.7E-18 T 09-03-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 Pfam PF00398 Ribosomal RNA adenine dimethylase 33 251 7.9E-41 T 09-03-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 29 286 4.1E-69 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 SUPERFAMILY SSF53335 29 289 3.93E-61 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS12805 2409fc70d7caff790c7d6f711e7e6d43 293 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 29 289 47.487 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 ARZXY2_RS15950 396904b75efae404cad2cbc2a8160478 340 SUPERFAMILY SSF161098 84 322 3.92E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15950 396904b75efae404cad2cbc2a8160478 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 329 1.5E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15950 396904b75efae404cad2cbc2a8160478 340 Gene3D G3DSA:1.10.3720.10 40 322 6.6E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Gene3D G3DSA:1.10.10.10 1 47 2.8E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Gene3D G3DSA:3.30.70.920 64 137 1.5E-6 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Gene3D G3DSA:3.30.70.920 234 318 2.1E-4 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Gene3D G3DSA:1.10.10.10 179 218 2.4E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 SUPERFAMILY SSF54909 64 146 1.34E-8 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 SUPERFAMILY SSF54909 238 318 6.17E-6 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Pfam PF13404 AsnC-type helix-turn-helix domain 7 44 7.2E-9 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 Pfam PF01037 Lrp/AsnC ligand binding domain 76 136 6.8E-6 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS00990 43e3f0a0054721de003dd1c55553b224 345 SMART SM00344 179 284 0.0013 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS14530 fb20a3828718db5bbf43b3445c2e4289 199 Pfam PF02108 Flagellar assembly protein FliH 71 185 2.8E-10 T 09-03-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE ARZXY2_RS02020 959a1681085ab794b058a5ba3b9e00b1 458 SUPERFAMILY SSF53850 49 456 3.8E-58 T 09-03-2017 ARZXY2_RS02020 959a1681085ab794b058a5ba3b9e00b1 458 Gene3D G3DSA:3.40.190.10 181 351 6.4E-25 T 09-03-2017 ARZXY2_RS02020 959a1681085ab794b058a5ba3b9e00b1 458 Pfam PF01547 Bacterial extracellular solute-binding protein 78 364 2.0E-29 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS02020 959a1681085ab794b058a5ba3b9e00b1 458 Gene3D G3DSA:3.40.190.10 53 174 1.1E-30 T 09-03-2017 ARZXY2_RS02020 959a1681085ab794b058a5ba3b9e00b1 458 Gene3D G3DSA:3.40.190.10 352 383 1.1E-30 T 09-03-2017 ARZXY2_RS20535 60ab0d34e70e4df890ab707612fc7335 151 Gene3D G3DSA:3.10.450.50 29 150 7.5E-41 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS20535 60ab0d34e70e4df890ab707612fc7335 151 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 26 149 26.401 T 09-03-2017 IPR023006 Uncharacterised protein family UPF0225 ARZXY2_RS20535 60ab0d34e70e4df890ab707612fc7335 151 SUPERFAMILY SSF54427 51 150 4.38E-32 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS20535 60ab0d34e70e4df890ab707612fc7335 151 Pfam PF02810 SEC-C motif 26 44 2.0E-5 T 09-03-2017 IPR004027 SEC-C motif ARZXY2_RS13510 8402933bd5ec7409d8ad9bcc48b8e8e4 123 Pfam PF04993 TfoX N-terminal domain 21 104 7.7E-13 T 09-03-2017 IPR007076 TfoX, N-terminal ARZXY2_RS13510 8402933bd5ec7409d8ad9bcc48b8e8e4 123 Gene3D G3DSA:3.30.1460.30 8 105 1.1E-8 T 09-03-2017 IPR007076 TfoX, N-terminal ARZXY2_RS13510 8402933bd5ec7409d8ad9bcc48b8e8e4 123 SUPERFAMILY SSF159894 8 106 9.94E-17 T 09-03-2017 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 Pfam PF00072 Response regulator receiver domain 5 114 7.5E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 Gene3D G3DSA:3.40.50.2300 2 123 3.8E-42 T 09-03-2017 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 SMART SM00862 146 222 2.2E-22 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 2.2E-25 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 SMART SM00448 3 113 1.9E-46 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 Gene3D G3DSA:1.10.10.10 124 221 1.8E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04750 47a3c86a1452185d219684a32d5404d8 224 SUPERFAMILY SSF52172 3 175 4.98E-44 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS03200 3941cbc16bb12bb65a550f7996802e41 280 Gene3D G3DSA:1.10.3720.10 3 267 8.6E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03200 3941cbc16bb12bb65a550f7996802e41 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 271 4.3E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03200 3941cbc16bb12bb65a550f7996802e41 280 SUPERFAMILY SSF161098 11 280 6.02E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09875 987e1e0d1b2969a075c96ca0eced0284 146 SUPERFAMILY SSF50475 18 142 3.45E-19 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09875 987e1e0d1b2969a075c96ca0eced0284 146 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 22 141 3.5E-19 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS09875 987e1e0d1b2969a075c96ca0eced0284 146 Gene3D G3DSA:2.30.110.10 15 144 5.1E-33 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS03855 3acd8c394cd20afdeb91b488c18630cc 40 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 40 15.239 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03855 3acd8c394cd20afdeb91b488c18630cc 40 SUPERFAMILY SSF57840 1 40 3.27E-11 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03855 3acd8c394cd20afdeb91b488c18630cc 40 Pfam PF00444 Ribosomal protein L36 1 40 5.6E-16 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS15930 25c54d53740600d305fe7a1b39327b10 392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 219 374 1.3E-37 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS15930 25c54d53740600d305fe7a1b39327b10 392 Gene3D G3DSA:3.30.70.270 221 377 6.3E-46 T 09-03-2017 ARZXY2_RS15930 25c54d53740600d305fe7a1b39327b10 392 SUPERFAMILY SSF55073 224 376 6.12E-41 T 09-03-2017 IPR029787 Nucleotide cyclase ARZXY2_RS15930 25c54d53740600d305fe7a1b39327b10 392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 216 377 2.9E-43 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS15930 25c54d53740600d305fe7a1b39327b10 392 SMART SM00267 208 378 5.0E-46 T 09-03-2017 IPR000160 GGDEF domain ARZXY2_RS19105 8ec04408512d40334a02cc84c399f6fd 331 Gene3D G3DSA:3.40.190.10 132 258 3.0E-18 T 09-03-2017 ARZXY2_RS19105 8ec04408512d40334a02cc84c399f6fd 331 Pfam PF09084 NMT1/THI5 like 56 269 4.3E-35 T 09-03-2017 IPR015168 SsuA/THI5-like ARZXY2_RS19105 8ec04408512d40334a02cc84c399f6fd 331 SUPERFAMILY SSF53850 50 285 2.29E-36 T 09-03-2017 ARZXY2_RS19105 8ec04408512d40334a02cc84c399f6fd 331 SMART SM00062 45 269 0.0053 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS00650 a4628c7d3de5eaf8493cb05c49612a95 506 Pfam PF04717 Type VI secretion system, phage-baseplate injector 348 451 3.7E-9 T 09-03-2017 IPR006531 Gp5 N-terminal ARZXY2_RS00650 a4628c7d3de5eaf8493cb05c49612a95 506 Gene3D G3DSA:2.40.50.230 361 421 1.8E-7 T 09-03-2017 IPR006531 Gp5 N-terminal ARZXY2_RS00650 a4628c7d3de5eaf8493cb05c49612a95 506 SUPERFAMILY SSF69279 26 180 1.81E-11 T 09-03-2017 ARZXY2_RS00650 a4628c7d3de5eaf8493cb05c49612a95 506 SUPERFAMILY SSF69255 350 422 2.22E-9 T 09-03-2017 ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 SMART SM00895 97 221 2.3E-24 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 Pfam PF07729 FCD domain 97 220 2.3E-26 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 9.2E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 2.4E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 2.4E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 Gene3D G3DSA:1.10.10.10 3 74 1.6E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 SUPERFAMILY SSF48008 95 227 1.6E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 Gene3D G3DSA:1.20.120.530 93 228 1.5E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 SMART SM00345 10 69 2.4E-22 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17460 89777469907513f777ae9f689b0902d3 233 SUPERFAMILY SSF46785 3 73 9.62E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04990 84fbdb841b579028082017fc0a135b2a 488 Gene3D G3DSA:1.20.1250.20 271 454 2.9E-15 T 09-03-2017 ARZXY2_RS04990 84fbdb841b579028082017fc0a135b2a 488 Pfam PF07690 Major Facilitator Superfamily 24 415 1.4E-36 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS04990 84fbdb841b579028082017fc0a135b2a 488 Gene3D G3DSA:1.20.1250.20 12 199 1.7E-24 T 09-03-2017 ARZXY2_RS04990 84fbdb841b579028082017fc0a135b2a 488 SUPERFAMILY SSF103473 8 200 1.01E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS04990 84fbdb841b579028082017fc0a135b2a 488 SUPERFAMILY SSF103473 254 456 1.01E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS01885 e208ee38a4242f9c7396f09a465b5f9c 548 SUPERFAMILY SSF53335 181 351 7.69E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01885 e208ee38a4242f9c7396f09a465b5f9c 548 Gene3D G3DSA:3.40.50.150 176 322 1.8E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01885 e208ee38a4242f9c7396f09a465b5f9c 548 Pfam PF05175 Methyltransferase small domain 155 274 4.1E-13 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 ARZXY2_RS01885 e208ee38a4242f9c7396f09a465b5f9c 548 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 263 269 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ARZXY2_RS02735 16275d96528307a6b316165bc1cd40ae 337 Pfam PF01569 PAP2 superfamily 177 249 1.2E-6 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS02735 16275d96528307a6b316165bc1cd40ae 337 SUPERFAMILY SSF48317 67 250 6.7E-19 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS02735 16275d96528307a6b316165bc1cd40ae 337 SMART SM00014 142 247 2.0E-5 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS02735 16275d96528307a6b316165bc1cd40ae 337 Gene3D G3DSA:1.20.144.10 122 243 9.0E-13 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 Gene3D G3DSA:1.20.1080.10 4 238 4.2E-75 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 PRINTS PR00783 Major intrinsic protein family signature 5 24 2.3E-28 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 PRINTS PR00783 Major intrinsic protein family signature 46 70 2.3E-28 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 PRINTS PR00783 Major intrinsic protein family signature 146 164 2.3E-28 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 PRINTS PR00783 Major intrinsic protein family signature 221 241 2.3E-28 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 PRINTS PR00783 Major intrinsic protein family signature 174 196 2.3E-28 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 ProSitePatterns PS00221 MIP family signature. 64 72 - T 09-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 SUPERFAMILY SSF81338 6 241 2.75E-57 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 ARZXY2_RS08210 4de9c3d3cc5fa4d1d94de93d56de39a6 250 Pfam PF00230 Major intrinsic protein 7 237 4.7E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 SUPERFAMILY SSF55594 144 223 7.33E-19 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 PRINTS PR00107 Phosphocarrier protein signature 174 189 5.6E-8 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 PRINTS PR00107 Phosphocarrier protein signature 189 206 5.6E-8 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 PRINTS PR00107 Phosphocarrier protein signature 153 169 5.6E-8 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 153 160 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 3 124 6.7E-36 T 09-03-2017 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 SUPERFAMILY SSF53062 1 124 2.62E-32 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 Gene3D G3DSA:3.40.50.510 1 125 1.5E-41 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 Pfam PF00381 PTS HPr component phosphorylation site 144 217 8.2E-20 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 Pfam PF03610 PTS system fructose IIA component 4 118 1.6E-25 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 145 217 2.2E-17 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17805 5994b6cab7bbdee671d756a343815906 224 Gene3D G3DSA:3.30.1340.10 143 223 5.9E-21 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 SUPERFAMILY SSF46785 27 81 2.78E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 Gene3D G3DSA:3.30.420.40 88 229 4.7E-43 T 09-03-2017 ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 Gene3D G3DSA:3.30.420.40 230 372 9.4E-46 T 09-03-2017 ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 SUPERFAMILY SSF53067 92 392 2.02E-57 T 09-03-2017 ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 ProSitePatterns PS01125 ROK family signature. 225 252 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 Gene3D G3DSA:1.10.10.10 27 85 2.0E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15605 2930fa89ebb97a92f84eca1992e8b712 406 Pfam PF00480 ROK family 93 390 1.8E-60 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS08485 cf8dc97d397ad424250dc55bf67900f2 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 250 2.8E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS08485 cf8dc97d397ad424250dc55bf67900f2 275 SUPERFAMILY SSF161098 32 236 5.49E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS08485 cf8dc97d397ad424250dc55bf67900f2 275 Gene3D G3DSA:1.10.3720.10 31 251 8.3E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS08485 cf8dc97d397ad424250dc55bf67900f2 275 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 31 145 3.1E-13 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS07845 b55e2228189ae937dd3959262e82df70 163 SUPERFAMILY SSF48371 12 156 6.04E-15 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 ARZXY2_RS07845 b55e2228189ae937dd3959262e82df70 163 Pfam PF08713 DNA alkylation repair enzyme 13 157 6.1E-14 T 09-03-2017 IPR014825 DNA alkylation repair enzyme ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 833 955 2.1E-27 T 09-03-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 149 170 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 8.5E-35 T 09-03-2017 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 Pfam PF00361 Proton-conducting membrane transporter 125 403 1.2E-63 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 Pfam PF13244 Domain of unknown function (DUF4040) 617 680 9.7E-19 T 09-03-2017 IPR025383 Domain of unknown function DUF4040 ARZXY2_RS00360 13c081f4c41356fe95a135c03cb2b3ab 993 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 60 105 2.2E-8 T 09-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 Gene3D G3DSA:3.50.50.60 109 299 1.9E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 305 1.1E-116 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 09-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-35 T 09-03-2017 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-35 T 09-03-2017 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.8E-35 T 09-03-2017 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.8E-35 T 09-03-2017 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 1.8E-35 T 09-03-2017 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 294 1.5E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 Gene3D G3DSA:3.50.50.60 5 108 3.4E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 SUPERFAMILY SSF51905 5 305 6.05E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 286 305 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS00570 a3a85dae59471446a96e9010a440283a 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 1.5E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS03425 ab920a8a148e540924df181dcabc3299 389 Gene3D G3DSA:3.40.630.30 36 180 5.4E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03425 ab920a8a148e540924df181dcabc3299 389 Pfam PF00583 Acetyltransferase (GNAT) family 78 143 9.4E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS03425 ab920a8a148e540924df181dcabc3299 389 SUPERFAMILY SSF55729 263 373 4.01E-6 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03425 ab920a8a148e540924df181dcabc3299 389 Gene3D G3DSA:3.40.630.30 265 371 2.0E-4 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03425 ab920a8a148e540924df181dcabc3299 389 SUPERFAMILY SSF55729 31 146 5.48E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 SMART SM00482 316 519 1.5E-10 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 Gene3D G3DSA:1.10.150.20 339 475 1.5E-14 T 09-03-2017 ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 Pfam PF00476 DNA polymerase family A 213 552 7.8E-32 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 SUPERFAMILY SSF56672 160 560 1.33E-67 T 09-03-2017 ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 Gene3D G3DSA:3.30.70.370 476 557 4.2E-12 T 09-03-2017 ARZXY2_RS01820 a1f2f23df16d79895624547f600b70a0 560 Gene3D G3DSA:3.30.70.370 300 338 4.2E-12 T 09-03-2017 ARZXY2_RS03710 ba296bead0875ac81085127adbc30200 347 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 25 71 2.8E-12 T 09-03-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal ARZXY2_RS10810 f5d3277e6dc37a6f9a3959b937c589e3 95 Pfam PF02325 YGGT family 10 88 2.4E-11 T 09-03-2017 IPR003425 CCB3/YggT GO:0016020 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 SUPERFAMILY SSF54373 252 329 1.57E-7 T 09-03-2017 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 SUPERFAMILY SSF51905 334 394 3.99E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 SUPERFAMILY SSF51905 23 244 3.99E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Gene3D G3DSA:3.50.50.60 165 243 2.6E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Gene3D G3DSA:3.50.50.60 15 101 2.6E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Gene3D G3DSA:3.50.50.60 334 392 2.6E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Pfam PF01266 FAD dependent oxidoreductase 24 370 1.2E-56 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 13 398 1.3E-189 T 09-03-2017 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Gene3D G3DSA:3.30.9.10 244 333 1.1E-20 T 09-03-2017 ARZXY2_RS20360 9b926f095ac8aa5f4e7d980ff528a986 406 Gene3D G3DSA:3.30.9.10 105 164 1.1E-20 T 09-03-2017 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 Gene3D G3DSA:1.10.357.10 74 189 6.1E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 SUPERFAMILY SSF46689 16 83 1.08E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 2.0E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 Gene3D G3DSA:1.10.10.60 20 73 2.9E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ARZXY2_RS11710 c3adcd8678bf8c7527934e3f82ed2fe0 211 SUPERFAMILY SSF48498 94 184 2.27E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS12505 8b39ed83c0d844769ca2a6eaadf77836 452 SMART SM00507 350 400 5.2E-9 T 09-03-2017 IPR003615 HNH nuclease ARZXY2_RS12505 8b39ed83c0d844769ca2a6eaadf77836 452 Pfam PF01844 HNH endonuclease 366 404 2.1E-7 T 09-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 ARZXY2_RS12505 8b39ed83c0d844769ca2a6eaadf77836 452 Pfam PF02720 Domain of unknown function (DUF222) 43 241 8.2E-12 T 09-03-2017 IPR003870 Domain of unknown function DUF222 ARZXY2_RS03735 1c93d600d2c80f95618c9cf167044686 168 SUPERFAMILY SSF54211 45 168 1.37E-42 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS03735 1c93d600d2c80f95618c9cf167044686 168 Pfam PF00380 Ribosomal protein S9/S16 47 168 3.4E-43 T 09-03-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03735 1c93d600d2c80f95618c9cf167044686 168 ProSitePatterns PS00360 Ribosomal protein S9 signature. 106 124 - T 09-03-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03735 1c93d600d2c80f95618c9cf167044686 168 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 38 168 31.851 T 09-03-2017 IPR023035 Ribosomal protein S9, bacterial/plastid ARZXY2_RS03735 1c93d600d2c80f95618c9cf167044686 168 Gene3D G3DSA:3.30.230.10 45 168 1.6E-47 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS05855 ee5de1eb1978862903bd719e85b2830e 209 Gene3D G3DSA:1.10.3540.10 7 201 1.6E-60 T 09-03-2017 IPR023137 DUF1819 domain ARZXY2_RS05855 ee5de1eb1978862903bd719e85b2830e 209 Pfam PF08849 Putative inner membrane protein (DUF1819) 10 188 2.9E-52 T 09-03-2017 IPR014948 Protein of unknown function DUF1819, putative inner membrane ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 ProSitePatterns PS00216 Sugar transport proteins signature 1. 301 318 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 Gene3D G3DSA:1.20.1250.20 68 217 1.6E-17 T 09-03-2017 ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 Gene3D G3DSA:1.20.1250.20 239 425 5.9E-23 T 09-03-2017 ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 85 110 - T 09-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 SUPERFAMILY SSF103473 67 426 4.05E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS07275 1b7f66874cabbf0f4e7b9bbae4fd46ef 428 Pfam PF07690 Major Facilitator Superfamily 41 296 1.8E-22 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Pfam PF00575 S1 RNA binding domain 36 108 2.0E-14 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Pfam PF00575 S1 RNA binding domain 124 191 1.2E-13 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Pfam PF00575 S1 RNA binding domain 208 280 2.5E-25 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Pfam PF00575 S1 RNA binding domain 294 366 1.6E-20 T 09-03-2017 IPR003029 S1 domain GO:0003676 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SUPERFAMILY SSF50249 32 133 1.5E-21 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SUPERFAMILY SSF50249 209 293 2.5E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SUPERFAMILY SSF50249 280 368 1.99E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Gene3D G3DSA:2.40.50.140 212 286 2.8E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Gene3D G3DSA:2.40.50.140 287 369 2.5E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SUPERFAMILY SSF50249 110 194 1.79E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SMART SM00316 210 280 1.9E-27 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SMART SM00316 124 191 1.3E-10 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SMART SM00316 295 366 4.3E-24 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 SMART SM00316 37 108 3.9E-15 T 09-03-2017 IPR022967 RNA-binding domain, S1 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Gene3D G3DSA:2.40.50.140 116 192 1.1E-15 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 Gene3D G3DSA:2.40.50.140 31 109 1.5E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 57 71 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 232 253 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 175 195 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 310 329 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 39 57 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 105 124 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 129 145 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 146 163 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS09175 29fc122c7192b731464c2033bf7c33bc 491 PRINTS PR00681 Ribosomal protein S1 signature 349 367 1.7E-86 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 249 28.479 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 131 148 - T 09-03-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 109 1.2E-23 T 09-03-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 44 244 3.2E-53 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 PIRSF PIRSF000161 3 250 3.7E-63 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 SUPERFAMILY SSF51735 5 136 2.23E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 Gene3D G3DSA:3.40.50.720 5 144 6.8E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 113 239 6.4E-28 T 09-03-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11445 d2e1816835fa5c9bdc2ea97b8c1eb4c4 252 SUPERFAMILY SSF55347 110 220 6.98E-41 T 09-03-2017 ARZXY2_RS09235 12c9a3444a908d9d7ac49db4a9c2b8b6 277 PIRSF PIRSF020623 1 276 4.6E-74 T 09-03-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 ARZXY2_RS09235 12c9a3444a908d9d7ac49db4a9c2b8b6 277 Pfam PF08223 PaaX-like protein C-terminal domain 95 260 6.4E-43 T 09-03-2017 IPR013225 PaaX-like, C-terminal ARZXY2_RS09235 12c9a3444a908d9d7ac49db4a9c2b8b6 277 Pfam PF07848 PaaX-like protein 8 64 3.8E-9 T 09-03-2017 IPR012906 PaaX-like, N-terminal ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Pfam PF02817 e3 binding domain 235 269 1.1E-10 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 SUPERFAMILY SSF52777 291 530 1.07E-75 T 09-03-2017 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 SUPERFAMILY SSF47005 233 274 2.49E-9 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Gene3D G3DSA:4.10.320.10 233 278 5.3E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 SUPERFAMILY SSF51230 3 93 5.63E-25 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Gene3D G3DSA:2.40.50.100 4 93 7.9E-26 T 09-03-2017 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Pfam PF00364 Biotin-requiring enzyme 5 76 1.7E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 296 530 1.1E-74 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS20020 721c7ba4ac6412bd8ffde301dca1befa 531 Gene3D G3DSA:3.30.559.10 291 530 3.0E-77 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 Hamap MF_00822 Urease accessory protein UreE [ureE]. 1 158 22.282 T 09-03-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 SMART SM00988 6 73 2.9E-18 T 09-03-2017 IPR004029 UreE urease accessory, N-terminal ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 Pfam PF02814 UreE urease accessory protein, N-terminal domain 19 73 2.6E-17 T 09-03-2017 IPR004029 UreE urease accessory, N-terminal ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 Gene3D G3DSA:3.30.70.790 79 158 2.2E-23 T 09-03-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 SUPERFAMILY SSF69737 79 153 1.7E-16 T 09-03-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 Pfam PF05194 UreE urease accessory protein, C-terminal domain 81 146 6.3E-6 T 09-03-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 PIRSF PIRSF036402 1 158 9.3E-48 T 09-03-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 Gene3D G3DSA:2.60.260.20 1 77 1.6E-24 T 09-03-2017 ARZXY2_RS17575 93d6a52fc2052aec65d4d0767c571513 158 SUPERFAMILY SSF69287 1 77 3.14E-18 T 09-03-2017 IPR004029 UreE urease accessory, N-terminal ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 Gene3D G3DSA:3.40.309.10 259 440 8.6E-60 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 Gene3D G3DSA:3.40.605.10 3 258 1.3E-86 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 SUPERFAMILY SSF53720 2 462 1.96E-149 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15470 edd154c30344b95cde3ca3577dcbe93b 465 Pfam PF00171 Aldehyde dehydrogenase family 17 460 1.0E-147 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0011 T 09-03-2017 ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 Gene3D G3DSA:3.40.50.720 1 227 1.8E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 SUPERFAMILY SSF51735 2 225 6.18E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 Pfam PF00106 short chain dehydrogenase 9 192 2.2E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.4E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.4E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00840 e69be326c1e247bd6d66838a1c2c091a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.4E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS05425 00b54907451df9a8ee984ed40dabd62c 352 Pfam PF03747 ADP-ribosylglycohydrolase 16 327 3.3E-57 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 ARZXY2_RS05425 00b54907451df9a8ee984ed40dabd62c 352 SUPERFAMILY SSF101478 8 350 6.93E-59 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 ARZXY2_RS18935 675495676467583f88651901e46ee238 182 Gene3D G3DSA:1.10.3300.10 3 178 5.0E-44 T 09-03-2017 IPR023286 ABATE domain ARZXY2_RS18935 675495676467583f88651901e46ee238 182 Pfam PF07336 Putative stress-induced transcription regulator 12 129 1.4E-15 T 09-03-2017 IPR010852 Putative stress-induced transcription regulator ARZXY2_RS18935 675495676467583f88651901e46ee238 182 Pfam PF11706 CGNR zinc finger 134 177 2.2E-15 T 09-03-2017 IPR021005 Zinc finger, CGNR ARZXY2_RS18935 675495676467583f88651901e46ee238 182 SUPERFAMILY SSF160904 2 176 3.4E-44 T 09-03-2017 ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 Pfam PF13183 4Fe-4S dicluster domain 170 242 1.8E-11 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 SUPERFAMILY SSF46548 131 257 1.53E-32 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 33 252 1.2E-78 T 09-03-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 Gene3D G3DSA:3.10.20.30 27 130 2.1E-37 T 09-03-2017 IPR012675 Beta-grasp domain ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 Gene3D G3DSA:1.10.1060.10 131 258 3.0E-39 T 09-03-2017 ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 30 135 2.0E-34 T 09-03-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13220 9b4ca4be49481f5ac3f395c9173b7f24 260 SUPERFAMILY SSF54292 27 130 2.59E-27 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 ARZXY2_RS07770 dd838d093bb761f66baecda733295288 245 Gene3D G3DSA:1.25.40.10 79 129 1.9E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-11 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 Gene3D G3DSA:3.40.190.10 147 184 1.4E-4 T 09-03-2017 ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 Gene3D G3DSA:1.10.10.10 1 86 3.1E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 Gene3D G3DSA:3.40.190.10 185 270 1.1E-19 T 09-03-2017 ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 SUPERFAMILY SSF53850 93 305 2.17E-21 T 09-03-2017 ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 SUPERFAMILY SSF46785 1 86 6.78E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12305 e35c3dee284f3ebca5c4449444e3cc4f 309 Pfam PF03466 LysR substrate binding domain 93 299 4.1E-21 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Pfam PF08245 Mur ligase middle domain 122 300 3.0E-27 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 SUPERFAMILY SSF53244 319 459 2.14E-41 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 406 1.5E-23 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Pfam PF01225 Mur ligase family, catalytic domain 20 118 4.2E-23 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 17 462 37.858 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 SUPERFAMILY SSF51984 19 105 7.59E-24 T 09-03-2017 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 SUPERFAMILY SSF53623 103 317 5.27E-59 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 20 452 3.9E-142 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Gene3D G3DSA:3.40.50.720 19 105 1.7E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Gene3D G3DSA:3.40.1190.10 106 322 5.1E-76 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS10840 a2dd0050f2692c7877f64d462e4dc1c4 462 Gene3D G3DSA:3.90.190.20 323 460 1.5E-47 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 ARZXY2_RS01505 02f49c5da1f5df42c1c2d765836db855 760 SMART SM00947 572 746 1.6E-38 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS01505 02f49c5da1f5df42c1c2d765836db855 760 SUPERFAMILY SSF53056 543 746 1.2E-46 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS01505 02f49c5da1f5df42c1c2d765836db855 760 Gene3D G3DSA:3.40.1050.10 530 748 3.0E-55 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS01505 02f49c5da1f5df42c1c2d765836db855 760 Pfam PF00484 Carbonic anhydrase 579 742 7.8E-39 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS01505 02f49c5da1f5df42c1c2d765836db855 760 Pfam PF00916 Sulfate permease family 31 383 4.3E-68 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 Gene3D G3DSA:3.40.50.150 10 43 5.1E-78 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 Gene3D G3DSA:3.40.50.150 79 279 5.1E-78 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 SUPERFAMILY SSF53335 6 279 1.39E-65 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 34 40 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 Pfam PF01555 DNA methylase 33 274 9.0E-43 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 30 44 1.2E-22 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 217 234 1.2E-22 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 259 279 1.2E-22 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 95 115 1.2E-22 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS04390 b8bc99a0c751f68142baf26a6388533f 283 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 236 254 1.2E-22 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 Pfam PF11896 Domain of unknown function (DUF3416) 16 209 2.4E-54 T 09-03-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 Pfam PF00128 Alpha amylase, catalytic domain 246 340 7.9E-5 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 14 681 43.738 T 09-03-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 SUPERFAMILY SSF51445 207 577 3.91E-80 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 Gene3D G3DSA:3.20.20.80 213 576 1.1E-63 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14840 465617277b28b175d34c22c4c97ad00b 683 SMART SM00642 215 571 3.8E-4 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 319 8.1E-35 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 SUPERFAMILY SSF52283 3 134 3.59E-38 T 09-03-2017 ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 SUPERFAMILY SSF51735 101 288 1.0E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 2.5E-58 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 Gene3D G3DSA:3.40.50.720 115 290 1.7E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17600 21d42898ef0cec1c18b5c22e901be3b7 320 Gene3D G3DSA:3.40.50.720 2 114 2.7E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 6 406 9.6E-154 T 09-03-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 Gene3D G3DSA:3.40.50.2000 187 382 4.8E-40 T 09-03-2017 ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 Pfam PF00534 Glycosyl transferases group 1 213 383 1.5E-34 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 Pfam PF13439 Glycosyltransferase Family 4 25 205 1.7E-33 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 5 410 43.76 T 09-03-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 ARZXY2_RS03800 d807d1ff717b34a6fa980b68f149faf2 418 SUPERFAMILY SSF53756 24 404 3.08E-87 T 09-03-2017 ARZXY2_RS13210 a4c9db5f1831ccb69d977ce33b4677d0 153 SUPERFAMILY SSF81343 13 142 4.14E-34 T 09-03-2017 ARZXY2_RS13210 a4c9db5f1831ccb69d977ce33b4677d0 153 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 17 124 6.9E-16 T 09-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13210 a4c9db5f1831ccb69d977ce33b4677d0 153 Gene3D G3DSA:1.20.950.10 13 137 1.2E-35 T 09-03-2017 ARZXY2_RS05875 c6c9dac9d80e331ef04d137a86804efe 831 Pfam PF08665 PglZ domain 444 616 4.6E-57 T 09-03-2017 IPR013973 PglZ domain ARZXY2_RS05875 c6c9dac9d80e331ef04d137a86804efe 831 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 10 803 1.6E-219 T 09-03-2017 IPR014060 Conserved hypothetical protein CHP02687 ARZXY2_RS05875 c6c9dac9d80e331ef04d137a86804efe 831 SUPERFAMILY SSF53649 443 617 1.7E-8 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ARZXY2_RS05875 c6c9dac9d80e331ef04d137a86804efe 831 Gene3D G3DSA:3.40.720.10 683 719 1.7E-6 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ARZXY2_RS05875 c6c9dac9d80e331ef04d137a86804efe 831 Gene3D G3DSA:3.40.720.10 532 615 1.7E-6 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 372 2.2E-174 T 09-03-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 SUPERFAMILY SSF51412 118 372 8.63E-72 T 09-03-2017 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 SUPERFAMILY SSF51412 13 78 8.63E-72 T 09-03-2017 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 Gene3D G3DSA:3.20.20.70 17 372 1.7E-77 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 SMART SM01240 15 375 1.6E-22 T 09-03-2017 ARZXY2_RS03905 8ca48c4e9ed1d001e3f547df7d1d1283 378 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 302 3.5E-43 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Gene3D G3DSA:2.40.30.110 296 369 8.1E-27 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 SUPERFAMILY SSF101790 296 375 6.38E-23 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 PIRSF PIRSF006487 1 377 7.6E-91 T 09-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 375 4.8E-104 T 09-03-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Gene3D G3DSA:3.30.1360.120 4 54 6.2E-50 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Gene3D G3DSA:3.30.1360.120 145 244 6.2E-50 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 265 2.2E-89 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Gene3D G3DSA:3.30.70.1400 55 141 1.2E-28 T 09-03-2017 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 375 41.596 T 09-03-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 274 369 1.4E-21 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS14395 d7a8e050ed3defd4353093fb08fcd25f 377 SUPERFAMILY SSF103025 3 289 3.61E-88 T 09-03-2017 ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 Pfam PF00717 Peptidase S24-like 59 125 5.4E-13 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 Gene3D G3DSA:2.10.109.10 29 142 8.5E-40 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 SUPERFAMILY SSF51306 25 140 5.58E-32 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 95 107 6.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 67 78 6.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS17710 b32b7eeff305ca9928df972b84327448 143 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 56 66 6.7E-10 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS20010 9e37e94085e6500133c21bc518e03e73 394 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 29 378 8.7E-130 T 09-03-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS20010 9e37e94085e6500133c21bc518e03e73 394 Gene3D G3DSA:3.40.50.970 22 375 1.2E-126 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS20010 9e37e94085e6500133c21bc518e03e73 394 Pfam PF00676 Dehydrogenase E1 component 64 335 4.7E-73 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 ARZXY2_RS20010 9e37e94085e6500133c21bc518e03e73 394 SUPERFAMILY SSF52518 48 387 1.02E-97 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Gene3D G3DSA:2.102.10.10 363 496 3.0E-23 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Gene3D G3DSA:3.50.50.60 159 238 4.5E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Gene3D G3DSA:3.50.50.60 14 113 4.5E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Gene3D G3DSA:3.50.50.60 328 362 4.5E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Pfam PF01266 FAD dependent oxidoreductase 24 366 1.4E-34 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 SUPERFAMILY SSF50022 418 495 3.01E-18 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 Pfam PF00355 Rieske [2Fe-2S] domain 433 496 1.7E-7 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 SUPERFAMILY SSF51905 328 377 2.46E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07850 5deadc0ce500c4df16a0cc5fc21358c0 503 SUPERFAMILY SSF51905 22 240 2.46E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 SUPERFAMILY SSF52540 459 504 2.6E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 SUPERFAMILY SSF52540 211 418 2.6E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 23 549 3.9E-257 T 09-03-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 ProSitePatterns PS00674 AAA-protein family signature. 371 389 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 Pfam PF16450 Proteasomal ATPase OB/ID domain 87 210 2.1E-45 T 09-03-2017 IPR032501 Proteasomal ATPase, OB/ID domain ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 SMART SM00382 249 403 6.6E-20 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 253 401 1.3E-46 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 Gene3D G3DSA:3.40.50.300 203 426 1.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08665 83a3658fedcc4f937479a26d0ba2f525 572 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 25 550 50.845 T 09-03-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 ARZXY2_RS15005 e09e4f546996287073de7288ca8a7f22 521 Pfam PF13520 Amino acid permease 18 453 9.3E-41 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS15005 e09e4f546996287073de7288ca8a7f22 521 PIRSF PIRSF006060 1 503 1.2E-63 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS16265 17fbb2d491f4d821f89455549876c5d9 281 SUPERFAMILY SSF51658 10 245 2.21E-34 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16265 17fbb2d491f4d821f89455549876c5d9 281 Gene3D G3DSA:3.20.20.150 15 247 5.9E-49 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS16265 17fbb2d491f4d821f89455549876c5d9 281 Pfam PF01261 Xylose isomerase-like TIM barrel 29 222 9.8E-26 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 Pfam PF00459 Inositol monophosphatase family 19 251 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 Gene3D G3DSA:3.40.190.80 199 268 1.6E-11 T 09-03-2017 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 92 105 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 Gene3D G3DSA:3.30.540.10 18 177 9.1E-37 T 09-03-2017 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 SUPERFAMILY SSF56655 16 278 1.05E-54 T 09-03-2017 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 72 88 3.6E-25 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 92 108 3.6E-25 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 198 219 3.6E-25 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 229 253 3.6E-25 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14120 ed1da2dd23734107cfd1b84ab98f80f8 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 50 70 3.6E-25 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS03325 7b2483c7f7b6d28be00298a6c7c413f5 199 SUPERFAMILY SSF50814 116 198 2.12E-40 T 09-03-2017 IPR011038 Calycin-like ARZXY2_RS03325 7b2483c7f7b6d28be00298a6c7c413f5 199 SUPERFAMILY SSF50814 8 81 2.12E-40 T 09-03-2017 IPR011038 Calycin-like ARZXY2_RS03325 7b2483c7f7b6d28be00298a6c7c413f5 199 Pfam PF08768 Domain of unknown function (DUF1794) 12 197 5.2E-43 T 09-03-2017 IPR014878 Domain of unknown function DUF1794 ARZXY2_RS03325 7b2483c7f7b6d28be00298a6c7c413f5 199 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 5 199 30.147 T 09-03-2017 IPR022939 Uncharacterised protein family UPF0678 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 SMART SM00354 10 80 6.1E-23 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 Gene3D G3DSA:3.40.50.2300 184 351 1.8E-38 T 09-03-2017 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 69 332 2.1E-29 T 09-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 SUPERFAMILY SSF53822 70 353 4.71E-62 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 SUPERFAMILY SSF47413 10 69 1.5E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 Gene3D G3DSA:1.10.260.40 11 62 1.3E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 6.5E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16070 f72522da565c3f762ef9c52c97f578d7 364 Gene3D G3DSA:3.40.50.2300 63 183 1.2E-40 T 09-03-2017 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 294 32.366 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Gene3D G3DSA:3.40.1380.10 64 197 4.6E-39 T 09-03-2017 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 SUPERFAMILY SSF52943 3 294 5.76E-79 T 09-03-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Gene3D G3DSA:1.10.287.80 243 289 2.7E-23 T 09-03-2017 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 294 8.5E-88 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Pfam PF00231 ATP synthase 5 294 2.2E-80 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Gene3D G3DSA:1.10.287.80 20 61 8.4E-26 T 09-03-2017 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 Gene3D G3DSA:1.10.287.80 209 242 8.4E-26 T 09-03-2017 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 PRINTS PR00126 ATP synthase gamma subunit signature 272 293 6.0E-32 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 6.0E-32 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 6.0E-32 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 PRINTS PR00126 ATP synthase gamma subunit signature 241 260 6.0E-32 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 ARZXY2_RS05255 8244444bf4236539aa164289e4a9abe8 296 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 280 293 - T 09-03-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 ARZXY2_RS16650 353644107a76e311dd547c3082e8845c 270 SUPERFAMILY SSF51695 3 248 1.44E-40 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS16650 353644107a76e311dd547c3082e8845c 270 Gene3D G3DSA:3.20.20.190 2 250 5.9E-44 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS16650 353644107a76e311dd547c3082e8845c 270 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 245 9.5E-27 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 Gene3D G3DSA:2.30.40.10 9 76 2.6E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 TIGRFAM TIGR01224 hutI: imidazolonepropionase 28 405 2.2E-92 T 09-03-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 SUPERFAMILY SSF51338 7 65 1.63E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 SUPERFAMILY SSF51338 368 407 1.63E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 Hamap MF_00372 Imidazolonepropionase [hutI]. 8 408 40.638 T 09-03-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 Pfam PF01979 Amidohydrolase family 62 383 4.4E-11 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 Gene3D G3DSA:3.20.20.140 77 356 3.2E-39 T 09-03-2017 ARZXY2_RS12285 904ad1735c61cf3e2031fce02cd00c46 409 SUPERFAMILY SSF51556 64 356 8.12E-60 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 Gene3D G3DSA:3.50.50.60 8 204 1.6E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 SUPERFAMILY SSF51905 10 78 9.5E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 SUPERFAMILY SSF51905 119 259 9.5E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 Pfam PF13454 FAD-NAD(P)-binding 10 197 5.2E-37 T 09-03-2017 ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 Gene3D G3DSA:3.50.50.60 591 608 8.9E-4 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS00070 126bb13cc34003ac2118d3e8a18a01dc 645 Gene3D G3DSA:3.50.50.60 453 470 8.9E-4 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 PIRSF PIRSF039085 8 250 9.1E-112 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 Gene3D G3DSA:3.40.50.300 10 245 2.5E-84 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 SMART SM00382 35 222 3.4E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 SUPERFAMILY SSF52540 10 244 1.73E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04310 fb6bbbe227c49a7e8907eea3babdfc19 251 Pfam PF00005 ABC transporter 26 174 2.8E-37 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS11885 7bf3a79c6998dd4f4a9004bb93da8233 79 SUPERFAMILY SSF52833 2 72 1.21E-16 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS11885 7bf3a79c6998dd4f4a9004bb93da8233 79 Gene3D G3DSA:3.40.30.10 3 73 1.6E-24 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS11885 7bf3a79c6998dd4f4a9004bb93da8233 79 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 72 2.2E-26 T 09-03-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 ARZXY2_RS11885 7bf3a79c6998dd4f4a9004bb93da8233 79 Pfam PF00462 Glutaredoxin 3 61 2.2E-13 T 09-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 Gene3D G3DSA:3.40.50.2300 172 331 3.8E-54 T 09-03-2017 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 SMART SM00354 3 73 8.7E-21 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 Gene3D G3DSA:1.10.260.40 2 53 9.0E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 SUPERFAMILY SSF53822 67 331 1.73E-65 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.5E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 09-03-2017 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 SUPERFAMILY SSF47413 2 61 1.02E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 6.2E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 6.2E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 Pfam PF13377 Periplasmic binding protein-like domain 170 330 3.0E-38 T 09-03-2017 ARZXY2_RS01265 1792e437d5e240c20c1ec5ba7ed85c33 331 Gene3D G3DSA:3.40.50.2300 54 171 1.6E-29 T 09-03-2017 ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 Gene3D G3DSA:1.10.8.10 34 63 5.7E-6 T 09-03-2017 ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 Gene3D G3DSA:3.40.50.150 68 238 4.6E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 7 253 1.7E-111 T 09-03-2017 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 SUPERFAMILY SSF53335 43 221 4.15E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 Pfam PF05175 Methyltransferase small domain 84 179 1.3E-7 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 ARZXY2_RS17300 49fcb536c3dcf7973021a5d7612c6d32 256 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 33 229 5.7E-41 T 09-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 ARZXY2_RS14490 59d61225cdc7edbe2ec6a0cc0d14238c 82 Pfam PF01381 Helix-turn-helix 22 69 2.2E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS14490 59d61225cdc7edbe2ec6a0cc0d14238c 82 SMART SM00530 18 72 9.8E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS14490 59d61225cdc7edbe2ec6a0cc0d14238c 82 Gene3D G3DSA:1.10.260.40 12 70 7.9E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS14490 59d61225cdc7edbe2ec6a0cc0d14238c 82 SUPERFAMILY SSF47413 13 76 6.97E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12955 c315d1e046b522cd9438c080b2fea356 204 SUPERFAMILY SSF53056 3 199 5.23E-53 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS12955 c315d1e046b522cd9438c080b2fea356 204 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 52 59 - T 09-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS12955 c315d1e046b522cd9438c080b2fea356 204 SMART SM00947 40 199 9.4E-47 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS12955 c315d1e046b522cd9438c080b2fea356 204 Pfam PF00484 Carbonic anhydrase 47 194 2.5E-36 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS12955 c315d1e046b522cd9438c080b2fea356 204 Gene3D G3DSA:3.40.1050.10 5 199 1.3E-51 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 ARZXY2_RS12325 1c914a41ee838af2471ad8d8b30e1f99 517 Pfam PF00665 Integrase core domain 120 243 5.1E-20 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS12325 1c914a41ee838af2471ad8d8b30e1f99 517 Gene3D G3DSA:3.30.420.10 119 285 5.3E-17 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS12325 1c914a41ee838af2471ad8d8b30e1f99 517 SUPERFAMILY SSF53098 117 286 1.67E-17 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS02540 1c914a41ee838af2471ad8d8b30e1f99 517 Pfam PF00665 Integrase core domain 120 243 5.1E-20 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS02540 1c914a41ee838af2471ad8d8b30e1f99 517 Gene3D G3DSA:3.30.420.10 119 285 5.3E-17 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS02540 1c914a41ee838af2471ad8d8b30e1f99 517 SUPERFAMILY SSF53098 117 286 1.67E-17 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS14475 480bbe54b6c597a8c1cf9cc091982389 272 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 60 1.9E-18 T 09-03-2017 IPR025713 Motility protein B, N-terminal domain ARZXY2_RS14475 480bbe54b6c597a8c1cf9cc091982389 272 Gene3D G3DSA:3.30.1330.60 135 242 1.1E-19 T 09-03-2017 IPR006665 OmpA-like domain ARZXY2_RS14475 480bbe54b6c597a8c1cf9cc091982389 272 SUPERFAMILY SSF103088 135 242 1.57E-19 T 09-03-2017 IPR006665 OmpA-like domain ARZXY2_RS14475 480bbe54b6c597a8c1cf9cc091982389 272 Pfam PF00691 OmpA family 140 236 4.1E-15 T 09-03-2017 IPR006665 OmpA-like domain ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Gene3D G3DSA:3.40.50.300 28 198 4.2E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Gene3D G3DSA:3.40.50.300 291 376 1.3E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Gene3D G3DSA:3.40.50.300 225 258 1.3E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Pfam PF12029 Domain of unknown function (DUF3516) 379 841 7.2E-207 T 09-03-2017 IPR021904 Protein of unknown function DUF3516 ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Pfam PF00270 DEAD/DEAH box helicase 38 185 3.2E-12 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 SUPERFAMILY SSF52540 288 381 1.8E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 SUPERFAMILY SSF52540 48 255 1.8E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 Pfam PF00271 Helicase conserved C-terminal domain 289 368 2.8E-6 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 SMART SM00490 278 368 1.5E-13 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS09130 5262900a9b31ad342ec08e7a8491f44b 844 SMART SM00487 32 215 1.6E-20 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 09-03-2017 IPR019844 Cold-shock conserved site ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 PIRSF PIRSF002599 1 67 3.2E-25 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 65 4.2E-30 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 Gene3D G3DSA:2.40.50.140 1 66 4.8E-32 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 PRINTS PR00050 Cold shock protein signature 40 58 1.6E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-18 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 SUPERFAMILY SSF50249 1 66 6.09E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS14325 98c648a11832a9cf4e55fed9b78e1fd6 67 SMART SM00357 3 67 9.7E-30 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 ARZXY2_RS13360 7bae2e96f887b8c8f0735ca49fbadcb4 242 Pfam PF00005 ABC transporter 31 180 4.7E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13360 7bae2e96f887b8c8f0735ca49fbadcb4 242 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13360 7bae2e96f887b8c8f0735ca49fbadcb4 242 SUPERFAMILY SSF52540 24 230 3.9E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13360 7bae2e96f887b8c8f0735ca49fbadcb4 242 Gene3D G3DSA:3.40.50.300 8 229 1.6E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13360 7bae2e96f887b8c8f0735ca49fbadcb4 242 SMART SM00382 40 231 2.2E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06570 14c1784171c0408858c900f04570e1b4 414 Pfam PF07728 AAA domain (dynein-related subfamily) 23 161 8.1E-11 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 ARZXY2_RS06570 14c1784171c0408858c900f04570e1b4 414 SMART SM00382 17 169 1.9E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06570 14c1784171c0408858c900f04570e1b4 414 SUPERFAMILY SSF52540 14 208 1.54E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06570 14c1784171c0408858c900f04570e1b4 414 ProSitePatterns PS00018 EF-hand calcium-binding domain. 212 224 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site ARZXY2_RS06570 14c1784171c0408858c900f04570e1b4 414 Gene3D G3DSA:3.40.50.300 13 187 4.6E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16180 4a85e686f3e348072d78d050eb9ddf84 382 SUPERFAMILY SSF53474 321 342 2.86E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS16180 4a85e686f3e348072d78d050eb9ddf84 382 SUPERFAMILY SSF53474 107 251 2.86E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS16180 4a85e686f3e348072d78d050eb9ddf84 382 Gene3D G3DSA:3.40.50.1820 108 226 2.5E-10 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17440 cac565b20d2ed5e56e6548fa82e76478 489 PIRSF PIRSF002746 24 485 1.1E-133 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS17440 cac565b20d2ed5e56e6548fa82e76478 489 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 30 482 9.9E-98 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS17440 cac565b20d2ed5e56e6548fa82e76478 489 Pfam PF02447 GntP family permease 29 480 2.7E-118 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 Gene3D G3DSA:3.40.50.2300 176 336 1.7E-63 T 09-03-2017 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 SUPERFAMILY SSF53822 67 336 4.57E-79 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 Pfam PF13377 Periplasmic binding protein-like domain 174 335 6.4E-42 T 09-03-2017 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 21 31 7.6E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 11 21 7.6E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 SMART SM00354 9 76 5.2E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 SUPERFAMILY SSF47413 9 60 3.28E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 09-03-2017 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 Gene3D G3DSA:1.10.260.40 10 64 3.3E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 54 4.8E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13630 f528ba3dc5d4c72c0240e1ba9e6f4b63 339 Gene3D G3DSA:3.40.50.2300 65 175 1.2E-22 T 09-03-2017 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 SUPERFAMILY SSF51351 10 264 6.28E-87 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 11 265 38.549 T 09-03-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 Gene3D G3DSA:3.20.20.70 11 264 3.8E-100 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 ProSitePatterns PS00171 Triosephosphate isomerase active site. 180 190 - T 09-03-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 Pfam PF00121 Triosephosphate isomerase 14 262 1.3E-83 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09065 98bf6fb3cca067eded41f3be087751b9 271 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 14 255 1.4E-51 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS03550 3ff92e6fe452347510efbd7a08a15dba 119 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 113 21.9 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03550 3ff92e6fe452347510efbd7a08a15dba 119 SUPERFAMILY SSF50104 3 103 3.07E-26 T 09-03-2017 IPR008991 Translation protein SH3-like domain ARZXY2_RS03550 3ff92e6fe452347510efbd7a08a15dba 119 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 119 1.9E-29 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03550 3ff92e6fe452347510efbd7a08a15dba 119 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 45 119 7.7E-23 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03550 3ff92e6fe452347510efbd7a08a15dba 119 Gene3D G3DSA:2.30.30.30 3 96 5.5E-24 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 ARZXY2_RS18495 70117328149eb031df680dfa0be10d99 284 Pfam PF01694 Rhomboid family 114 249 3.6E-30 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ARZXY2_RS18495 70117328149eb031df680dfa0be10d99 284 SUPERFAMILY SSF144091 76 254 4.97E-43 T 09-03-2017 ARZXY2_RS18495 70117328149eb031df680dfa0be10d99 284 Gene3D G3DSA:1.20.1540.10 76 249 5.3E-41 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ARZXY2_RS18495 70117328149eb031df680dfa0be10d99 284 Pfam PF00643 B-box zinc finger 15 41 4.2E-5 T 09-03-2017 IPR000315 B-box-type zinc finger GO:0005622|GO:0008270 ARZXY2_RS02140 774ac3dfef1f082a415fa5c05c0a9115 183 Gene3D G3DSA:2.40.128.110 10 179 1.8E-59 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like ARZXY2_RS02140 774ac3dfef1f082a415fa5c05c0a9115 183 SUPERFAMILY SSF101874 10 178 5.62E-56 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like ARZXY2_RS02140 774ac3dfef1f082a415fa5c05c0a9115 183 Pfam PF04264 YceI-like domain 12 176 2.4E-44 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like ARZXY2_RS02140 774ac3dfef1f082a415fa5c05c0a9115 183 SMART SM00867 11 178 1.3E-68 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 SUPERFAMILY SSF88697 246 311 3.08E-9 T 09-03-2017 IPR015947 PUA-like domain ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 15 229 1.8E-66 T 09-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 236 3.0E-14 T 09-03-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 246 310 6.6E-13 T 09-03-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 36 190 3.8E-48 T 09-03-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 14 309 17.322 T 09-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS11530 21cf46f09c461b077bfee23636a00030 333 SUPERFAMILY SSF55120 14 236 3.17E-71 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS16655 3c56e96aad4919af343adb6b6bc69c09 237 PRINTS PR01837 MgtC/SapB protein signature 8 27 3.2E-43 T 09-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 ARZXY2_RS16655 3c56e96aad4919af343adb6b6bc69c09 237 PRINTS PR01837 MgtC/SapB protein signature 27 45 3.2E-43 T 09-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 ARZXY2_RS16655 3c56e96aad4919af343adb6b6bc69c09 237 PRINTS PR01837 MgtC/SapB protein signature 61 83 3.2E-43 T 09-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 ARZXY2_RS16655 3c56e96aad4919af343adb6b6bc69c09 237 PRINTS PR01837 MgtC/SapB protein signature 88 112 3.2E-43 T 09-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 ARZXY2_RS16655 3c56e96aad4919af343adb6b6bc69c09 237 Pfam PF02308 MgtC family 5 131 2.0E-36 T 09-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 SUPERFAMILY SSF53901 8 258 9.77E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 385 7.1E-107 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Pfam PF00108 Thiolase, N-terminal domain 8 251 1.4E-58 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Pfam PF02803 Thiolase, C-terminal domain 269 386 2.8E-28 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Gene3D G3DSA:3.40.47.10 189 261 7.0E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Gene3D G3DSA:3.40.47.10 8 124 7.0E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 PIRSF PIRSF000429 2 388 4.6E-106 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 SUPERFAMILY SSF53901 264 385 2.04E-29 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Gene3D G3DSA:3.40.47.10 267 386 6.1E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08965 df318145f94166e94de22c779355b330 390 Gene3D G3DSA:3.40.47.10 146 188 6.1E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS13975 773060a4ccaf191989bb67a9ad2673d5 160 SUPERFAMILY SSF46785 8 143 9.79E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13975 773060a4ccaf191989bb67a9ad2673d5 160 Gene3D G3DSA:1.10.10.10 7 144 3.8E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13975 773060a4ccaf191989bb67a9ad2673d5 160 SMART SM00347 29 128 3.3E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13975 773060a4ccaf191989bb67a9ad2673d5 160 Pfam PF12802 MarR family 42 92 7.5E-12 T 09-03-2017 ARZXY2_RS09540 d3f965258f2912f89631ae5521b6ba19 363 SUPERFAMILY SSF55961 158 354 2.2E-37 T 09-03-2017 ARZXY2_RS09540 d3f965258f2912f89631ae5521b6ba19 363 Pfam PF00355 Rieske [2Fe-2S] domain 42 121 8.7E-14 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS09540 d3f965258f2912f89631ae5521b6ba19 363 Gene3D G3DSA:2.102.10.10 40 149 9.8E-22 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS09540 d3f965258f2912f89631ae5521b6ba19 363 SUPERFAMILY SSF50022 38 148 8.64E-25 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 SUPERFAMILY SSF51445 301 483 8.64E-33 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 SUPERFAMILY SSF51445 564 666 8.64E-33 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 SUPERFAMILY SSF51445 102 257 8.64E-33 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 TIGRFAM TIGR02455 TreS_stutzeri: trehalose synthase 81 757 5.0E-266 T 09-03-2017 IPR012665 Trehalose synthase ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 Gene3D G3DSA:3.20.20.80 334 498 1.3E-16 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 Gene3D G3DSA:3.20.20.80 128 275 1.3E-16 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS19000 640d95df5e5fa82634e04fce43ad1c22 769 Pfam PF00128 Alpha amylase, catalytic domain 196 380 8.4E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Gene3D G3DSA:2.60.40.10 1658 1747 1.7E-12 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 SUPERFAMILY SSF49265 1472 1644 1.82E-30 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 SMART SM00060 1474 1547 9.8E-13 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 SMART SM00060 1656 1740 7.7E-4 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 SMART SM00060 1562 1641 2.6E-5 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 SUPERFAMILY SSF49265 1656 1747 4.33E-13 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Gene3D G3DSA:2.60.40.10 1472 1556 1.1E-18 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Pfam PF00041 Fibronectin type III domain 1475 1550 1.5E-9 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Pfam PF00041 Fibronectin type III domain 1661 1741 3.7E-8 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Pfam PF00041 Fibronectin type III domain 1564 1644 1.0E-8 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 ARZXY2_RS12455 789ad190231ce3bdd54949975580bbd1 2043 Gene3D G3DSA:2.60.40.10 1558 1655 2.8E-13 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS03390 ad54f87543001e7cc27c4cf7fb0a9bb5 409 Gene3D G3DSA:3.90.1150.10 281 407 3.2E-35 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS03390 ad54f87543001e7cc27c4cf7fb0a9bb5 409 Pfam PF00155 Aminotransferase class I and II 38 400 5.0E-73 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS03390 ad54f87543001e7cc27c4cf7fb0a9bb5 409 Gene3D G3DSA:3.40.640.10 50 280 1.6E-79 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS03390 ad54f87543001e7cc27c4cf7fb0a9bb5 409 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ARZXY2_RS03390 ad54f87543001e7cc27c4cf7fb0a9bb5 409 SUPERFAMILY SSF53383 9 407 6.05E-116 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS00400 f13e20a0a6acd24e025e9985e41cba09 206 PIRSF PIRSF037394 6 204 2.9E-56 T 09-03-2017 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted ARZXY2_RS00400 f13e20a0a6acd24e025e9985e41cba09 206 Pfam PF09819 ABC-type cobalt transport system, permease component 16 137 8.5E-39 T 09-03-2017 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted ARZXY2_RS00315 1dfc6ec8cd849d7dadb8d3ca937c185f 517 SUPERFAMILY SSF55166 115 254 9.94E-36 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 ARZXY2_RS00315 1dfc6ec8cd849d7dadb8d3ca937c185f 517 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 119 248 3.8E-38 T 09-03-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 ARZXY2_RS00315 1dfc6ec8cd849d7dadb8d3ca937c185f 517 SUPERFAMILY SSF69318 217 463 1.99E-5 T 09-03-2017 ARZXY2_RS09415 0101f750f7af4225d260e02f3a82a83d 139 Gene3D G3DSA:3.10.129.10 10 136 1.7E-24 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09415 0101f750f7af4225d260e02f3a82a83d 139 Pfam PF03061 Thioesterase superfamily 22 93 9.5E-8 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS09415 0101f750f7af4225d260e02f3a82a83d 139 SUPERFAMILY SSF54637 8 135 9.96E-22 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS04215 a1219319902f3be86a25fd474450c506 308 SUPERFAMILY SSF161098 91 289 1.7E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04215 a1219319902f3be86a25fd474450c506 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 6.1E-40 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04215 a1219319902f3be86a25fd474450c506 308 Gene3D G3DSA:1.10.3720.10 89 303 9.8E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01165 63603f54e0aa666c05a1ae4633dd5394 192 SUPERFAMILY SSF54001 11 187 2.28E-18 T 09-03-2017 ARZXY2_RS01165 63603f54e0aa666c05a1ae4633dd5394 192 Gene3D G3DSA:3.90.70.10 118 187 4.1E-7 T 09-03-2017 ARZXY2_RS01165 63603f54e0aa666c05a1ae4633dd5394 192 Pfam PF00648 Calpain family cysteine protease 35 156 9.0E-10 T 09-03-2017 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 Reactome: R-HSA-1474228 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 Gene3D G3DSA:3.50.50.60 492 555 1.7E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 Gene3D G3DSA:3.50.50.60 10 282 1.7E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 Pfam PF00890 FAD binding domain 17 540 1.4E-93 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 PIRSF PIRSF036654 11 558 2.1E-251 T 09-03-2017 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 SUPERFAMILY SSF51905 13 292 5.94E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08355 1c081b0e4547f0270a84609e2744b54a 558 SUPERFAMILY SSF51905 495 555 5.94E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 SUPERFAMILY SSF55174 146 223 1.59E-13 T 09-03-2017 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 SUPERFAMILY SSF55120 215 396 7.38E-42 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 Gene3D G3DSA:3.10.290.10 156 221 3.1E-22 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 224 384 1.7E-45 T 09-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 SMART SM00363 158 222 1.8E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 Pfam PF00849 RNA pseudouridylate synthase 220 354 7.6E-22 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 Pfam PF01479 S4 domain 158 201 6.2E-11 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11040 1c17ee85bbbe0db6c907a2016e717316 398 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 260 274 - T 09-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 SUPERFAMILY SSF55961 179 433 1.33E-39 T 09-03-2017 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 198 430 5.3E-42 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 SUPERFAMILY SSF50022 30 174 3.27E-45 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 Gene3D G3DSA:2.102.10.10 61 165 7.7E-35 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 Gene3D G3DSA:3.90.380.10 166 415 4.7E-7 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 77 92 4.8E-20 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 47 72 4.8E-20 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 119 139 4.8E-20 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 98 118 4.8E-20 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 197 219 4.8E-20 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 ARZXY2_RS16380 1cc251abd7f0666ec35e425d3e6e312f 434 Pfam PF00355 Rieske [2Fe-2S] domain 62 146 1.8E-16 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS13795 2599ac5ea9c4042a6c8f5c3ac1d8b0bd 449 Pfam PF07690 Major Facilitator Superfamily 32 400 9.9E-40 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS13795 2599ac5ea9c4042a6c8f5c3ac1d8b0bd 449 Gene3D G3DSA:1.20.1250.20 26 224 1.9E-37 T 09-03-2017 ARZXY2_RS13795 2599ac5ea9c4042a6c8f5c3ac1d8b0bd 449 Gene3D G3DSA:1.20.1250.20 239 438 6.0E-14 T 09-03-2017 ARZXY2_RS13795 2599ac5ea9c4042a6c8f5c3ac1d8b0bd 449 SUPERFAMILY SSF103473 16 440 2.09E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS07050 aa2b0010cd8c90c048184544d0d5c1bb 118 Gene3D G3DSA:3.40.1350.10 11 117 5.6E-32 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 ARZXY2_RS07050 aa2b0010cd8c90c048184544d0d5c1bb 118 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 114 19.674 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 ARZXY2_RS07050 aa2b0010cd8c90c048184544d0d5c1bb 118 SUPERFAMILY SSF52980 10 106 1.61E-20 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS07050 aa2b0010cd8c90c048184544d0d5c1bb 118 Pfam PF02021 Uncharacterised protein family UPF0102 11 101 8.1E-26 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 Gene3D G3DSA:3.90.180.10 1 170 1.8E-52 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 134 2.4E-27 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 SUPERFAMILY SSF51735 142 296 1.41E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 3 329 1.4E-149 T 09-03-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 SUPERFAMILY SSF50129 14 168 5.93E-44 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS09940 c11dd0cd5c71525560bd4d2646a30320 332 Gene3D G3DSA:3.40.50.720 171 276 4.6E-10 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17005 bca1aeaea19c1e0ecd6d690bbc155111 525 SUPERFAMILY SSF52096 227 505 3.78E-73 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS17005 bca1aeaea19c1e0ecd6d690bbc155111 525 SUPERFAMILY SSF52096 22 265 2.78E-61 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS17005 bca1aeaea19c1e0ecd6d690bbc155111 525 Gene3D G3DSA:3.90.226.10 25 256 1.5E-58 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS17005 bca1aeaea19c1e0ecd6d690bbc155111 525 Gene3D G3DSA:3.90.226.10 257 518 5.4E-68 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS17005 bca1aeaea19c1e0ecd6d690bbc155111 525 Pfam PF01039 Carboxyl transferase domain 45 513 3.3E-131 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS02555 bcc0c14ff7631339b7d99cc97252a521 136 Pfam PF01610 Transposase 2 125 5.6E-17 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS03235 a4a46106b3ace6feef925e9c64da08be 287 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 22 222 8.5E-22 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS03235 a4a46106b3ace6feef925e9c64da08be 287 SUPERFAMILY SSF51621 20 237 9.77E-48 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS03235 a4a46106b3ace6feef925e9c64da08be 287 PIRSF PIRSF015582 3 286 1.2E-54 T 09-03-2017 IPR011206 Citrate lyase beta subunit-like ARZXY2_RS03235 a4a46106b3ace6feef925e9c64da08be 287 Gene3D G3DSA:3.20.20.60 20 237 4.4E-57 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09445 ac1e8da8e1d312d69b0928940d0a95b6 278 SUPERFAMILY SSF56529 55 268 4.97E-72 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09445 ac1e8da8e1d312d69b0928940d0a95b6 278 Gene3D G3DSA:3.90.850.10 62 269 1.1E-72 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09445 ac1e8da8e1d312d69b0928940d0a95b6 278 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 67 268 1.9E-63 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 Pfam PF13604 AAA domain 812 963 4.6E-13 T 09-03-2017 ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 Gene3D G3DSA:3.40.50.300 1044 1174 2.6E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 99 532 2.9E-47 T 09-03-2017 IPR019993 RecB family nuclease, TM0106, putative ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 Pfam PF13482 RNase_H superfamily 338 532 1.1E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 SUPERFAMILY SSF52540 896 1167 6.96E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 SUPERFAMILY SSF52540 805 865 6.96E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 Gene3D G3DSA:3.40.50.300 802 1018 2.4E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13785 e773ffa281fc909a3dfd81c64be2b4b2 1192 Pfam PF13087 AAA domain 989 1163 1.2E-24 T 09-03-2017 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 Gene3D G3DSA:3.50.50.60 198 394 4.7E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 Gene3D G3DSA:3.50.50.60 9 69 4.7E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 50 1.7E-5 T 09-03-2017 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.9E-5 T 09-03-2017 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 316 1.9E-5 T 09-03-2017 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 201 219 1.9E-5 T 09-03-2017 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 SUPERFAMILY SSF51905 147 397 3.45E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 SUPERFAMILY SSF51905 9 105 3.45E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 Gene3D G3DSA:3.50.50.60 77 122 5.2E-7 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06685 72e2e28a17986e0ec7ddcdb6753bfd99 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 134 325 2.1E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Pfam PF13361 UvrD-like helicase C-terminal domain 382 825 1.2E-32 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 SUPERFAMILY SSF52980 998 1129 1.07E-6 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 SUPERFAMILY SSF52540 252 553 1.33E-113 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 SUPERFAMILY SSF52540 803 847 1.33E-113 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 SUPERFAMILY SSF52540 604 759 1.33E-113 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 SUPERFAMILY SSF52540 41 220 1.33E-113 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Pfam PF12705 PD-(D/E)XK nuclease superfamily 992 1140 5.8E-15 T 09-03-2017 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.90.320.10 1066 1128 1.4E-5 T 09-03-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Pfam PF00580 UvrD/REP helicase N-terminal domain 43 360 3.3E-53 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 799 847 3.7E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 384 516 3.7E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 720 755 3.7E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:1.10.486.10 517 562 7.3E-19 T 09-03-2017 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:1.10.486.10 594 698 7.3E-19 T 09-03-2017 ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 262 361 5.0E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 41 106 5.0E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04540 5ac67e69efeba092989725b98d4719be 1167 Gene3D G3DSA:3.40.50.300 140 202 5.0E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SUPERFAMILY SSF52540 966 1197 4.59E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Gene3D G3DSA:2.60.200.20 102 195 1.5E-18 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SMART SM00382 692 869 0.55 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SMART SM00382 1295 1411 1.5 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SMART SM00382 1017 1193 0.42 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SUPERFAMILY SSF49879 103 198 4.97E-19 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SUPERFAMILY SSF52540 664 875 8.77E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SMART SM00240 128 177 4.7E-6 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Gene3D G3DSA:3.40.50.300 1296 1323 2.1E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Gene3D G3DSA:3.40.50.300 1233 1257 2.1E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 SUPERFAMILY SSF52540 1290 1386 5.19E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 111 195 5.9E-15 T 09-03-2017 IPR032030 YscD, cytoplasmic domain ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Pfam PF01580 FtsK/SpoIIIE family 665 869 3.7E-29 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Pfam PF01580 FtsK/SpoIIIE family 1006 1196 1.1E-23 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Gene3D G3DSA:3.40.50.300 664 874 1.3E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12405 a460ae432006ce699d15c4bb10644979 1482 Gene3D G3DSA:3.40.50.300 961 1200 4.0E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 SMART SM00729 71 277 1.5E-10 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 Pfam PF04055 Radical SAM superfamily 81 235 1.1E-11 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 SUPERFAMILY SSF102114 42 307 1.7E-57 T 09-03-2017 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 TIGRFAM TIGR00510 lipA: lipoyl synthase 22 306 8.3E-102 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 3.0E-7 T 09-03-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 135.433 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 Gene3D G3DSA:3.20.20.70 43 302 3.5E-65 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10715 f0405b0775bc6c5fb95a02c8fd7c56a0 335 PIRSF PIRSF005963 4 318 1.1E-121 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 ARZXY2_RS09405 de35ede611c58b6577acffbc6ed0e35e 280 Pfam PF03618 Kinase/pyrophosphorylase 17 273 3.7E-68 T 09-03-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 ARZXY2_RS09405 de35ede611c58b6577acffbc6ed0e35e 280 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 14 280 70.366 T 09-03-2017 IPR026530 Phosphoenolpyruvate synthase regulatory protein ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 2.5E-28 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 SMART SM00862 148 224 3.9E-30 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 SUPERFAMILY SSF46894 127 225 4.82E-32 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 Gene3D G3DSA:3.40.50.2300 3 122 1.4E-38 T 09-03-2017 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 Pfam PF00072 Response regulator receiver domain 4 113 2.9E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 SMART SM00448 2 112 4.0E-41 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 Gene3D G3DSA:1.10.10.10 128 225 2.3E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14910 b196e0c4bd9b04aa03e95e8cb48962fe 226 SUPERFAMILY SSF52172 3 125 7.4E-39 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 Gene3D G3DSA:1.20.1250.20 265 426 2.5E-25 T 09-03-2017 ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 Gene3D G3DSA:1.20.1250.20 8 186 5.1E-38 T 09-03-2017 ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 Gene3D G3DSA:1.20.1250.20 459 484 2.5E-25 T 09-03-2017 ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 SUPERFAMILY SSF103473 457 482 3.66E-72 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 SUPERFAMILY SSF103473 251 423 3.66E-72 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 SUPERFAMILY SSF103473 6 192 3.66E-72 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 Pfam PF07690 Major Facilitator Superfamily 15 413 6.5E-62 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS03350 3d1e6e77aebfbfdf60aff453ab9a9375 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 425 5.5E-94 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 13 313 9.5E-120 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 302 7.0E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 7.7E-37 T 09-03-2017 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 7.7E-37 T 09-03-2017 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 7.7E-37 T 09-03-2017 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 7.7E-37 T 09-03-2017 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 7.7E-37 T 09-03-2017 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 47 62 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 9.3E-79 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 Gene3D G3DSA:3.50.50.60 120 307 7.7E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 143 163 - T 09-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 SUPERFAMILY SSF51905 9 313 5.78E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18615 6fc71858539864869bb25fcf389ba33e 318 Gene3D G3DSA:3.50.50.60 10 119 1.6E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 Gene3D G3DSA:3.40.50.970 68 485 2.7E-154 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 SUPERFAMILY SSF52518 490 721 1.65E-84 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 PIRSF PIRSF000156 9 911 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 Gene3D G3DSA:3.40.50.920 730 904 3.3E-63 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 SUPERFAMILY SSF52922 725 902 4.54E-47 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 318 5.0E-10 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 Gene3D G3DSA:3.40.50.970 490 725 1.9E-107 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 904 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS01640 c77d8d59de9d5039dee2fdcbb576abcd 917 SUPERFAMILY SSF52518 69 486 1.52E-131 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS18750 1bd45eaf1c21aef834416cc7acfab2b4 471 PIRSF PIRSF006060 1 464 2.0E-81 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS18750 1bd45eaf1c21aef834416cc7acfab2b4 471 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS18750 1bd45eaf1c21aef834416cc7acfab2b4 471 Pfam PF00324 Amino acid permease 15 443 4.5E-114 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS09095 fa1d72c2274671b707770a3d3d4c0999 307 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 23 306 39.303 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 ARZXY2_RS09095 fa1d72c2274671b707770a3d3d4c0999 307 Pfam PF03668 P-loop ATPase protein family 24 307 5.4E-100 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 ARZXY2_RS09095 fa1d72c2274671b707770a3d3d4c0999 307 Gene3D G3DSA:3.40.50.300 15 178 2.1E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09095 fa1d72c2274671b707770a3d3d4c0999 307 PIRSF PIRSF005052 23 307 3.6E-103 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 ARZXY2_RS09095 fa1d72c2274671b707770a3d3d4c0999 307 SUPERFAMILY SSF52540 23 179 9.67E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16340 e0674d3a66c3544b685475df6ed584cb 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 5 250 6.1E-84 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS16340 e0674d3a66c3544b685475df6ed584cb 251 SUPERFAMILY SSF52096 2 251 1.42E-89 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS16340 e0674d3a66c3544b685475df6ed584cb 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 92 112 - T 09-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 ARZXY2_RS16340 e0674d3a66c3544b685475df6ed584cb 251 Gene3D G3DSA:3.90.226.10 2 249 4.9E-98 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS05510 3e78080eddc67182c6f4b7902b87b76c 239 Pfam PF00293 NUDIX domain 43 140 5.1E-11 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS05510 3e78080eddc67182c6f4b7902b87b76c 239 Gene3D G3DSA:1.10.10.10 156 227 7.5E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05510 3e78080eddc67182c6f4b7902b87b76c 239 SUPERFAMILY SSF46785 164 227 4.35E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05510 3e78080eddc67182c6f4b7902b87b76c 239 Gene3D G3DSA:3.90.79.10 13 152 3.5E-37 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS05510 3e78080eddc67182c6f4b7902b87b76c 239 SUPERFAMILY SSF55811 45 159 2.44E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 Gene3D G3DSA:3.30.360.10 147 371 6.0E-36 T 09-03-2017 ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 SUPERFAMILY SSF51735 10 161 3.2E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 151 227 5.8E-9 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 133 6.0E-21 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 SUPERFAMILY SSF55347 140 277 1.57E-29 T 09-03-2017 ARZXY2_RS10065 1aece45fe48abe114de29718e24dd0a7 380 Gene3D G3DSA:3.40.50.720 9 146 1.6E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS20575 e5e5f9d21f1c0c5ef800afac0f78d55a 370 SUPERFAMILY SSF81345 42 364 8.63E-79 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS20575 e5e5f9d21f1c0c5ef800afac0f78d55a 370 Pfam PF01032 FecCD transport family 55 364 2.0E-86 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 ARZXY2_RS20575 e5e5f9d21f1c0c5ef800afac0f78d55a 370 Gene3D G3DSA:1.10.3470.10 40 366 7.9E-98 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 Pfam PF00717 Peptidase S24-like 59 122 1.2E-12 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 SUPERFAMILY SSF51306 17 138 9.42E-29 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 54 64 8.4E-7 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 65 76 8.4E-7 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 93 105 8.4E-7 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS06170 7f037528fa2e6e1db2272c7c8545477b 151 Gene3D G3DSA:2.10.109.10 27 138 3.6E-36 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 397 1.8E-25 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 238 8.4E-23 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Gene3D G3DSA:1.20.140.10 239 400 5.4E-39 T 09-03-2017 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Gene3D G3DSA:2.40.110.10 144 238 7.4E-32 T 09-03-2017 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 SUPERFAMILY SSF47203 252 401 3.22E-36 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 SUPERFAMILY SSF56645 29 248 4.97E-57 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 137 4.0E-16 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS16310 2dabe60cdf50bbc850cf2b583a6190f8 404 Gene3D G3DSA:1.10.540.10 34 139 8.8E-20 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 Gene3D G3DSA:1.10.1740.10 25 117 9.6E-25 T 09-03-2017 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 183 3.6E-33 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 Pfam PF08281 Sigma-70, region 4 128 179 2.6E-18 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 Gene3D G3DSA:1.10.10.10 121 184 1.2E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 SUPERFAMILY SSF88659 123 183 1.02E-17 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 SUPERFAMILY SSF88946 25 106 3.14E-22 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS04340 077d781f023dfa548c99a7d21cc61910 207 Pfam PF04542 Sigma-70 region 2 30 95 2.5E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 Gene3D G3DSA:1.20.1250.20 280 435 1.2E-14 T 09-03-2017 ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 Gene3D G3DSA:1.20.1250.20 487 514 1.2E-14 T 09-03-2017 ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 SUPERFAMILY SSF103473 486 514 4.32E-58 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 SUPERFAMILY SSF103473 263 434 4.32E-58 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 SUPERFAMILY SSF103473 21 216 4.32E-58 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 Pfam PF07690 Major Facilitator Superfamily 37 424 2.5E-41 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS14410 592dd637527a388b06321ea8b6f0705d 517 Gene3D G3DSA:1.20.1250.20 25 210 1.2E-30 T 09-03-2017 ARZXY2_RS18065 9dd9922bab7e35af5447a25adecf0671 356 Pfam PF06081 Aromatic acid exporter family member 1 24 159 1.2E-6 T 09-03-2017 IPR010343 Aromatic acid exporter family member 1 ARZXY2_RS18170 8b8ef38fb4cacf188974ece72075ba34 108 Pfam PF00581 Rhodanese-like domain 17 92 3.1E-12 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS18170 8b8ef38fb4cacf188974ece72075ba34 108 SUPERFAMILY SSF52821 14 100 2.1E-28 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS18170 8b8ef38fb4cacf188974ece72075ba34 108 SMART SM00450 2 96 2.2E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS18170 8b8ef38fb4cacf188974ece72075ba34 108 Gene3D G3DSA:3.40.250.10 16 100 8.6E-27 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 SUPERFAMILY SSF51569 5 363 9.89E-80 T 09-03-2017 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 Hamap MF_00493 Transaldolase [tal]. 1 371 159.014 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 PIRSF PIRSF036915 1 372 4.0E-166 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 ProSitePatterns PS01054 Transaldolase signature 1. 42 50 - T 09-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 Gene3D G3DSA:3.20.20.70 4 360 6.8E-120 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 Pfam PF00923 Transaldolase 16 360 2.1E-82 T 09-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 1.3E-131 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS09035 5e3811fe06bf47d9b73541fde56bd41a 372 ProSitePatterns PS00958 Transaldolase active site. 138 155 - T 09-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 ARZXY2_RS15850 e337c6651584e691b0ad3aa3fd03cd2d 158 SUPERFAMILY SSF46785 14 149 4.01E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15850 e337c6651584e691b0ad3aa3fd03cd2d 158 SMART SM00347 39 137 2.1E-18 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS15850 e337c6651584e691b0ad3aa3fd03cd2d 158 Pfam PF01047 MarR family 46 103 7.4E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS15850 e337c6651584e691b0ad3aa3fd03cd2d 158 Gene3D G3DSA:1.10.10.10 10 148 4.3E-35 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 SUPERFAMILY SSF103473 507 536 3.4E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 SUPERFAMILY SSF103473 263 435 3.4E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 SUPERFAMILY SSF103473 23 216 3.4E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 2.2E-6 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 2.2E-6 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 2.2E-6 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 Gene3D G3DSA:1.20.1250.20 509 537 1.8E-18 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 Gene3D G3DSA:1.20.1250.20 279 436 1.8E-18 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 Gene3D G3DSA:1.20.1250.20 24 209 1.2E-27 T 09-03-2017 ARZXY2_RS20265 24000d2c5ecbdc505671dfd66e447f16 550 Pfam PF07690 Major Facilitator Superfamily 26 425 5.1E-44 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS02330 98cf1a222d18ce810cb7d54f78c54af5 187 SUPERFAMILY SSF55729 6 176 8.47E-38 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS02330 98cf1a222d18ce810cb7d54f78c54af5 187 Gene3D G3DSA:3.40.630.30 1 182 4.0E-43 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS02330 98cf1a222d18ce810cb7d54f78c54af5 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 9.4E-26 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS15690 3fe93a6bd5c25798e19714bbcf156808 176 Pfam PF13673 Acetyltransferase (GNAT) domain 33 158 1.1E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS15690 3fe93a6bd5c25798e19714bbcf156808 176 Gene3D G3DSA:3.40.630.30 4 174 3.0E-34 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS15690 3fe93a6bd5c25798e19714bbcf156808 176 SUPERFAMILY SSF55729 4 173 8.72E-30 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS06915 f139203566b34c1722c2b31a0a32d541 516 Pfam PF07508 Recombinase 198 295 5.0E-16 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 ARZXY2_RS06915 f139203566b34c1722c2b31a0a32d541 516 SMART SM00857 32 179 5.4E-35 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS06915 f139203566b34c1722c2b31a0a32d541 516 Gene3D G3DSA:3.40.50.1390 32 160 4.4E-21 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS06915 f139203566b34c1722c2b31a0a32d541 516 SUPERFAMILY SSF53041 32 178 1.27E-23 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS06915 f139203566b34c1722c2b31a0a32d541 516 Pfam PF00239 Resolvase, N terminal domain 32 177 1.0E-23 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS09090 249ac6833f6500a351c35591bda6e616 338 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 27 293 1.1E-75 T 09-03-2017 IPR010119 Gluconeogenesis factor ARZXY2_RS09090 249ac6833f6500a351c35591bda6e616 338 Pfam PF01933 Uncharacterised protein family UPF0052 27 293 7.0E-62 T 09-03-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 ARZXY2_RS09090 249ac6833f6500a351c35591bda6e616 338 Hamap MF_00973 Gluconeogenesis factor. 23 337 29.559 T 09-03-2017 IPR010119 Gluconeogenesis factor ARZXY2_RS09090 249ac6833f6500a351c35591bda6e616 338 Gene3D G3DSA:3.40.50.10680 109 336 7.1E-38 T 09-03-2017 ARZXY2_RS09090 249ac6833f6500a351c35591bda6e616 338 SUPERFAMILY SSF142338 24 331 1.14E-76 T 09-03-2017 ARZXY2_RS17790 d32896588dd56df1a5659f701376026b 120 SUPERFAMILY SSF54593 8 118 8.25E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS17790 d32896588dd56df1a5659f701376026b 120 Gene3D G3DSA:3.10.180.10 9 118 8.8E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS03075 14903ed07ff25ffce36e449b18a0277e 324 SUPERFAMILY SSF48150 129 309 4.36E-27 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS03075 14903ed07ff25ffce36e449b18a0277e 324 Gene3D G3DSA:1.10.340.30 140 251 1.5E-16 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Gene3D G3DSA:3.90.600.10 323 416 3.8E-34 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 SUPERFAMILY SSF52440 2 100 1.32E-30 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Gene3D G3DSA:3.30.470.20 183 320 1.2E-54 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 40.847 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 SUPERFAMILY SSF51246 321 416 4.08E-28 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 413 1.1E-26 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 8.9E-150 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 2.7E-67 T 09-03-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Gene3D G3DSA:3.30.1490.20 122 182 1.1E-21 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Gene3D G3DSA:3.40.50.20 2 92 2.7E-31 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 2.4E-30 T 09-03-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 SUPERFAMILY SSF56059 102 311 7.42E-58 T 09-03-2017 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 09-03-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 SMART SM01209 101 287 6.4E-118 T 09-03-2017 ARZXY2_RS01675 4788f82b4e73a5133c8a1dd6d60e2208 436 SMART SM01210 322 417 8.4E-46 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 ARZXY2_RS19755 8b595bf3c5206f5746ca6637f3071069 422 Gene3D G3DSA:1.20.1250.20 10 198 1.7E-31 T 09-03-2017 ARZXY2_RS19755 8b595bf3c5206f5746ca6637f3071069 422 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 84 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS19755 8b595bf3c5206f5746ca6637f3071069 422 Gene3D G3DSA:1.20.1250.20 220 408 3.2E-23 T 09-03-2017 ARZXY2_RS19755 8b595bf3c5206f5746ca6637f3071069 422 SUPERFAMILY SSF103473 5 408 4.58E-71 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS19755 8b595bf3c5206f5746ca6637f3071069 422 Pfam PF07690 Major Facilitator Superfamily 18 273 1.9E-30 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS12590 9e39d091a924f0d6c9bbfa2aa22064b3 344 Gene3D G3DSA:3.30.950.10 206 325 5.8E-34 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12590 9e39d091a924f0d6c9bbfa2aa22064b3 344 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 92 299 1.6E-42 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12590 9e39d091a924f0d6c9bbfa2aa22064b3 344 Gene3D G3DSA:3.40.1010.10 90 205 5.1E-37 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12590 9e39d091a924f0d6c9bbfa2aa22064b3 344 SUPERFAMILY SSF53790 90 322 2.88E-62 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS12590 9e39d091a924f0d6c9bbfa2aa22064b3 344 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 91 321 9.4E-75 T 09-03-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 ARZXY2_RS03830 af8542ecaf25ae9b1b9458a46291dbe4 223 Pfam PF00814 Glycoprotease family 34 139 8.0E-27 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03830 af8542ecaf25ae9b1b9458a46291dbe4 223 Gene3D G3DSA:3.30.420.40 1 135 8.6E-38 T 09-03-2017 ARZXY2_RS03830 af8542ecaf25ae9b1b9458a46291dbe4 223 SUPERFAMILY SSF53067 115 207 3.24E-13 T 09-03-2017 ARZXY2_RS03830 af8542ecaf25ae9b1b9458a46291dbe4 223 SUPERFAMILY SSF53067 1 103 5.61E-23 T 09-03-2017 ARZXY2_RS03830 af8542ecaf25ae9b1b9458a46291dbe4 223 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 209 3.3E-50 T 09-03-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 ARZXY2_RS01150 68497654e7e21318c7e7283060bab4f0 276 Gene3D G3DSA:1.20.144.10 88 260 4.1E-30 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS01150 68497654e7e21318c7e7283060bab4f0 276 Pfam PF01569 PAP2 superfamily 144 257 2.0E-22 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS01150 68497654e7e21318c7e7283060bab4f0 276 SUPERFAMILY SSF48317 59 267 1.31E-35 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS01150 68497654e7e21318c7e7283060bab4f0 276 SMART SM00014 141 257 2.6E-20 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS14640 8b5512baa2ff9e83230e60024997228a 337 Gene3D G3DSA:3.60.110.10 16 320 8.0E-65 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS14640 8b5512baa2ff9e83230e60024997228a 337 SUPERFAMILY SSF56317 23 318 7.72E-60 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS14640 8b5512baa2ff9e83230e60024997228a 337 Pfam PF00795 Carbon-nitrogen hydrolase 25 300 1.2E-42 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS20295 12ba411d746cff007785858dbae465ca 380 SUPERFAMILY SSF69318 158 376 1.22E-29 T 09-03-2017 ARZXY2_RS20295 12ba411d746cff007785858dbae465ca 380 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 234 294 1.6E-7 T 09-03-2017 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 21 454 3.3E-73 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 Pfam PF08345 Flagellar M-ring protein C-terminal 249 396 4.2E-26 T 09-03-2017 IPR013556 Flagellar M-ring C-terminal ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PRINTS PR01009 Flagellar M-ring protein signature 121 139 1.6E-20 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PRINTS PR01009 Flagellar M-ring protein signature 262 280 1.6E-20 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PRINTS PR01009 Flagellar M-ring protein signature 196 214 1.6E-20 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PRINTS PR01009 Flagellar M-ring protein signature 332 356 1.6E-20 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PRINTS PR01009 Flagellar M-ring protein signature 153 167 1.6E-20 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 Pfam PF01514 Secretory protein of YscJ/FliF family 31 220 3.3E-68 T 09-03-2017 IPR006182 Secretory protein YscJ/FliF ARZXY2_RS14540 a82f9301d5be19f7658ae3c578329d16 544 PIRSF PIRSF004862 1 543 6.4E-121 T 09-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 Pfam PF00117 Glutamine amidotransferase class-I 210 392 7.8E-36 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 23 150 5.1E-51 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 SUPERFAMILY SSF52021 23 159 1.14E-53 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 Gene3D G3DSA:3.40.50.880 173 398 1.2E-62 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00096 Glutamine amidotransferase superfamily signature 247 256 5.9E-10 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00096 Glutamine amidotransferase superfamily signature 275 286 5.9E-10 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00096 Glutamine amidotransferase superfamily signature 369 382 5.9E-10 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 Gene3D G3DSA:3.50.30.20 22 162 3.7E-58 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 SMART SM01097 21 151 7.1E-85 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 SUPERFAMILY SSF52317 188 397 5.16E-49 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 244 258 2.2E-29 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 291 2.2E-29 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 292 309 2.2E-29 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 205 219 2.2E-29 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 317 328 2.2E-29 T 09-03-2017 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 21 398 45.418 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS08135 cf69761fcad57d4dad34a9ae8b7ccf01 415 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 23 395 1.1E-134 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 15 473 2.8E-237 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 147 360 1.2E-62 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 SUPERFAMILY SSF52540 93 365 1.86E-87 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Gene3D G3DSA:1.10.1140.10 363 480 1.2E-45 T 09-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 89 3.5E-19 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Gene3D G3DSA:2.40.10.170 9 91 2.8E-29 T 09-03-2017 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Gene3D G3DSA:3.40.50.300 92 362 8.0E-102 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 SUPERFAMILY SSF47917 363 479 1.12E-46 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 SMART SM00382 159 422 9.0E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 Hamap MF_01347 ATP synthase subunit beta [atpB]. 13 478 54.157 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 351 360 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05260 f9a0a198da00740c4e6804e07fae4aaa 483 SUPERFAMILY SSF50615 15 91 2.51E-24 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 Gene3D G3DSA:1.10.260.40 1 50 1.1E-26 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 Gene3D G3DSA:3.40.50.2300 170 323 3.4E-56 T 09-03-2017 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 1.3E-20 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 SMART SM00354 1 68 6.4E-27 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 SUPERFAMILY SSF53822 55 305 2.69E-62 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 09-03-2017 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 Pfam PF13377 Periplasmic binding protein-like domain 165 322 8.8E-41 T 09-03-2017 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 Gene3D G3DSA:3.40.50.2300 51 169 2.5E-30 T 09-03-2017 ARZXY2_RS00240 c87cb87be37ffcdec9bb0863bcbe1094 327 SUPERFAMILY SSF47413 1 56 7.19E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS06760 5f77e2b16aec8b015b8ff1ff808e290e 262 SMART SM00382 103 236 4.0E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06760 5f77e2b16aec8b015b8ff1ff808e290e 262 Pfam PF01695 IstB-like ATP binding protein 63 235 2.9E-61 T 09-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 ARZXY2_RS06760 5f77e2b16aec8b015b8ff1ff808e290e 262 SUPERFAMILY SSF52540 70 232 3.91E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06760 5f77e2b16aec8b015b8ff1ff808e290e 262 Gene3D G3DSA:3.40.50.300 71 234 1.6E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06760 5f77e2b16aec8b015b8ff1ff808e290e 262 PIRSF PIRSF003073 3 256 2.0E-81 T 09-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.7E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.7E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.7E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 Gene3D G3DSA:3.40.50.720 2 258 2.0E-63 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 SUPERFAMILY SSF51735 1 258 6.28E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09560 48e00e4ac3a54df36a4d067fa14b3a9d 262 Pfam PF00106 short chain dehydrogenase 9 200 1.4E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 Gene3D G3DSA:3.20.20.70 3 217 7.8E-83 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 PIRSF PIRSF001461 1 223 1.9E-85 T 09-03-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 200 3.8E-72 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 SUPERFAMILY SSF51366 3 213 1.77E-61 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 213 7.3E-75 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS10345 baa8971972fc4b86e5c3864f6b9b4c06 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 ARZXY2_RS05070 0e2351503fb32544dc8302130bd38a23 332 Gene3D G3DSA:3.40.50.1980 234 330 6.9E-5 T 09-03-2017 ARZXY2_RS05070 0e2351503fb32544dc8302130bd38a23 332 Gene3D G3DSA:3.40.50.1980 43 215 5.3E-42 T 09-03-2017 ARZXY2_RS05070 0e2351503fb32544dc8302130bd38a23 332 Pfam PF01297 Zinc-uptake complex component A periplasmic 53 328 1.2E-41 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 ARZXY2_RS05070 0e2351503fb32544dc8302130bd38a23 332 SUPERFAMILY SSF53807 46 330 1.72E-54 T 09-03-2017 ARZXY2_RS05400 9add7a6ec6ccf0317aad7d473afe0c80 132 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 4.4E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS05400 9add7a6ec6ccf0317aad7d473afe0c80 132 Gene3D G3DSA:1.10.10.10 2 71 6.3E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05400 9add7a6ec6ccf0317aad7d473afe0c80 132 SUPERFAMILY SSF46785 3 85 5.44E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.2E-16 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 SUPERFAMILY SSF46785 5 60 1.34E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 SMART SM00420 6 58 1.6E-17 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 SUPERFAMILY SSF100950 78 234 2.83E-17 T 09-03-2017 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 Gene3D G3DSA:1.10.10.10 5 57 1.8E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.2E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.2E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 SMART SM01134 73 232 4.0E-44 T 09-03-2017 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 Gene3D G3DSA:3.40.50.1360 79 129 3.8E-4 T 09-03-2017 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ARZXY2_RS18705 b7a141f244a4e51edb33ada11da94553 251 Pfam PF00455 DeoR C terminal sensor domain 76 230 8.8E-32 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS03190 342277390d0fc9b3b57256ea0c99e918 423 Pfam PF01547 Bacterial extracellular solute-binding protein 50 340 9.1E-31 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS03190 342277390d0fc9b3b57256ea0c99e918 423 Gene3D G3DSA:3.40.190.10 163 346 8.9E-44 T 09-03-2017 ARZXY2_RS03190 342277390d0fc9b3b57256ea0c99e918 423 Gene3D G3DSA:3.40.190.10 40 162 4.8E-12 T 09-03-2017 ARZXY2_RS03190 342277390d0fc9b3b57256ea0c99e918 423 SUPERFAMILY SSF53850 27 419 2.72E-54 T 09-03-2017 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 Gene3D G3DSA:3.40.50.270 98 221 6.8E-25 T 09-03-2017 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 SUPERFAMILY SSF52788 98 217 2.22E-24 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 100 217 8.0E-15 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 SMART SM00418 14 95 1.3E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 Gene3D G3DSA:1.10.10.10 17 91 6.1E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 6.0E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 6.0E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 SMART SM00347 17 112 0.0011 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 SUPERFAMILY SSF46785 16 91 2.55E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 Pfam PF12840 Helix-turn-helix domain 17 70 1.6E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS06670 0b5161c68c19dd1abab2d0b9997fde74 224 SMART SM00226 98 220 7.4E-17 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 Gene3D G3DSA:3.50.50.60 112 313 3.4E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 303 1.1E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 SUPERFAMILY SSF51905 7 313 4.13E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.4E-24 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.4E-24 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-24 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.4E-24 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.4E-24 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 SUPERFAMILY SSF55424 318 415 6.59E-17 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 Gene3D G3DSA:3.50.50.60 4 111 2.8E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 Pfam PF14759 Reductase C-terminal 323 413 5.4E-8 T 09-03-2017 IPR028202 Reductase, C-terminal ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 Gene3D G3DSA:3.30.390.30 323 414 5.7E-16 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 8.8E-16 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 8.8E-16 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 8.8E-16 T 09-03-2017 ARZXY2_RS04670 ca9e91cca7a9345e4c7d3931f91e0575 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.8E-16 T 09-03-2017 ARZXY2_RS19090 650fc4249c45a63d9fc690e48241cfb0 150 SUPERFAMILY SSF54427 4 135 1.42E-22 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS19090 650fc4249c45a63d9fc690e48241cfb0 150 Pfam PF13577 SnoaL-like domain 6 126 1.3E-12 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS19090 650fc4249c45a63d9fc690e48241cfb0 150 Gene3D G3DSA:3.10.450.50 5 133 1.9E-18 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS14005 874db2ded97b76db2d091d7b221d5036 381 Gene3D G3DSA:1.20.1260.10 36 117 6.1E-9 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS14005 874db2ded97b76db2d091d7b221d5036 381 Pfam PF01988 VIT family 157 373 4.0E-56 T 09-03-2017 IPR008217 Ccc1 family ARZXY2_RS06755 f7a12cc2bc0acc64ee7b81a7f125dfc3 385 Gene3D G3DSA:3.30.420.10 95 258 1.3E-13 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS06755 f7a12cc2bc0acc64ee7b81a7f125dfc3 385 SUPERFAMILY SSF53098 95 255 6.45E-12 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS06755 f7a12cc2bc0acc64ee7b81a7f125dfc3 385 Pfam PF00665 Integrase core domain 94 216 4.2E-14 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS06755 f7a12cc2bc0acc64ee7b81a7f125dfc3 385 Gene3D G3DSA:1.10.10.10 43 72 1.6E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02400 2ad3ae0bd3bc5b62680d12760d614449 190 SUPERFAMILY SSF117916 13 123 1.83E-19 T 09-03-2017 ARZXY2_RS02400 2ad3ae0bd3bc5b62680d12760d614449 190 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 24 189 1.5E-51 T 09-03-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 SUPERFAMILY SSF56645 16 238 1.26E-58 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Gene3D G3DSA:1.20.140.10 228 391 6.3E-36 T 09-03-2017 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 29 131 3.7E-16 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Gene3D G3DSA:1.10.540.10 17 134 2.3E-21 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 389 1.5E-24 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 SUPERFAMILY SSF47203 244 392 5.32E-36 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Gene3D G3DSA:2.40.110.10 136 227 1.3E-28 T 09-03-2017 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 139 151 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 ARZXY2_RS11820 0db32a0fb3b308fdf2f68b51df27b6ca 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 230 1.2E-23 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Pfam PF00571 CBS domain 284 337 2.7E-6 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Pfam PF00571 CBS domain 217 268 1.1E-5 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 SUPERFAMILY SSF54631 207 346 1.16E-30 T 09-03-2017 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 SUPERFAMILY SSF56176 356 433 1.5E-13 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Gene3D G3DSA:3.10.580.10 205 348 3.4E-23 T 09-03-2017 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 SMART SM01091 351 430 6.7E-17 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Pfam PF01595 Domain of unknown function DUF21 10 201 1.9E-31 T 09-03-2017 IPR002550 Domain of unknown function DUF21 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 SMART SM00116 289 337 6.9 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 SMART SM00116 226 275 0.2 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Gene3D G3DSA:3.30.465.10 357 428 1.7E-15 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS14980 737372e97edbf100c7c55a241595c5a8 451 Pfam PF03471 Transporter associated domain 355 429 1.0E-13 T 09-03-2017 IPR005170 Transporter-associated domain ARZXY2_RS17845 96f9322a15bb46b513b2780bbcbd3fc7 404 Gene3D G3DSA:3.40.50.2000 1 244 1.6E-52 T 09-03-2017 ARZXY2_RS17845 96f9322a15bb46b513b2780bbcbd3fc7 404 Gene3D G3DSA:3.40.50.2000 245 385 2.4E-52 T 09-03-2017 ARZXY2_RS17845 96f9322a15bb46b513b2780bbcbd3fc7 404 SUPERFAMILY SSF53756 1 401 5.42E-81 T 09-03-2017 ARZXY2_RS17845 96f9322a15bb46b513b2780bbcbd3fc7 404 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 301 382 1.3E-10 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 ARZXY2_RS17845 96f9322a15bb46b513b2780bbcbd3fc7 404 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 132 1.9E-7 T 09-03-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 SUPERFAMILY SSF51645 12 535 2.09E-174 T 09-03-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 17 535 1.6E-221 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 Gene3D G3DSA:1.20.1220.12 417 530 2.8E-24 T 09-03-2017 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 PIRSF PIRSF001363 2 537 7.1E-224 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 Pfam PF01274 Malate synthase 13 534 8.1E-180 T 09-03-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 ARZXY2_RS01565 922c98ce70f0dc0c362e55743e5a067f 537 Gene3D G3DSA:3.20.20.360 66 416 7.6E-115 T 09-03-2017 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 Gene3D G3DSA:3.20.20.140 74 424 3.1E-92 T 09-03-2017 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 Pfam PF01979 Amidohydrolase family 55 438 6.6E-22 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 Gene3D G3DSA:2.30.40.10 6 73 3.5E-18 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 SUPERFAMILY SSF51338 6 58 1.31E-25 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 SUPERFAMILY SSF51338 384 455 1.31E-25 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19555 d792e210a035db6d17a2d4b72f2b387b 473 SUPERFAMILY SSF51556 59 384 1.03E-81 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 SUPERFAMILY SSF53098 4 167 2.86E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 SMART SM00479 4 170 1.9E-15 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 SUPERFAMILY SSF52113 245 334 5.75E-8 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 Pfam PF00929 Exonuclease 7 160 4.5E-16 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 Gene3D G3DSA:3.30.420.10 4 170 9.5E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 Gene3D G3DSA:3.40.50.10190 244 335 1.5E-13 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS05415 c843faa3d44465d6bb18b4ea29efcb85 337 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 247 333 9.6E-5 T 09-03-2017 IPR001357 BRCT domain ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 Gene3D G3DSA:3.40.50.720 27 122 1.9E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 Gene3D G3DSA:3.40.50.720 123 294 1.5E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 SUPERFAMILY SSF51735 113 293 3.36E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 316 8.8E-22 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 292 3.2E-49 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS00775 bece2f68221aef45055a0a24b05ce17b 318 SUPERFAMILY SSF52283 26 147 1.02E-26 T 09-03-2017 ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 SUPERFAMILY SSF52540 16 235 3.9E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 Pfam PF00005 ABC transporter 20 191 9.4E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 Pfam PF00005 ABC transporter 349 496 3.8E-13 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 SMART SM00382 29 235 3.2E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 SMART SM00382 356 549 5.3E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 Gene3D G3DSA:3.40.50.300 137 278 7.9E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 Gene3D G3DSA:3.40.50.300 13 103 7.9E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 Gene3D G3DSA:3.40.50.300 348 548 3.5E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18695 60aa3fd7023a6c6ea7dfa79622bfcd7a 560 SUPERFAMILY SSF52540 347 546 4.84E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02725 0aa199b96cf4a60bbe52f6835d469f5c 405 SUPERFAMILY SSF103473 19 403 2.88E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS02725 0aa199b96cf4a60bbe52f6835d469f5c 405 Gene3D G3DSA:1.20.1250.20 223 402 9.2E-24 T 09-03-2017 ARZXY2_RS02725 0aa199b96cf4a60bbe52f6835d469f5c 405 Gene3D G3DSA:1.20.1250.20 20 194 6.3E-23 T 09-03-2017 ARZXY2_RS02725 0aa199b96cf4a60bbe52f6835d469f5c 405 Pfam PF07690 Major Facilitator Superfamily 24 229 2.3E-17 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS14180 ff1ea21fb54640382768eb86ca338de3 219 Gene3D G3DSA:1.10.3720.10 17 215 3.8E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS14180 ff1ea21fb54640382768eb86ca338de3 219 SUPERFAMILY SSF161098 15 215 3.01E-46 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS14180 ff1ea21fb54640382768eb86ca338de3 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 3.1E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS14180 ff1ea21fb54640382768eb86ca338de3 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 108 1.6E-29 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS04485 f66df9ebbd1fc4bc56b90e2b4c91e43d 292 Gene3D G3DSA:3.40.50.10090 148 287 1.2E-18 T 09-03-2017 ARZXY2_RS04485 f66df9ebbd1fc4bc56b90e2b4c91e43d 292 SUPERFAMILY SSF69618 14 285 2.22E-42 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04485 f66df9ebbd1fc4bc56b90e2b4c91e43d 292 Gene3D G3DSA:3.40.50.10090 12 140 3.4E-26 T 09-03-2017 ARZXY2_RS04485 f66df9ebbd1fc4bc56b90e2b4c91e43d 292 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 277 2.4E-52 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Gene3D G3DSA:3.40.50.300 17 267 5.5E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Gene3D G3DSA:3.40.50.300 304 555 2.6E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Pfam PF00005 ABC transporter 331 481 2.3E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Pfam PF00005 ABC transporter 39 194 3.3E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 SUPERFAMILY SSF52540 18 265 5.97E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 281 1.8E-7 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 533 558 6.2E-5 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 SMART SM00382 47 243 1.9E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 SMART SM00382 339 531 4.3E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS04225 b2713ffe0d93cb3c1b3b332e7fe997d8 569 SUPERFAMILY SSF52540 305 553 1.64E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 SUPERFAMILY SSF51735 4 166 1.77E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 Gene3D G3DSA:3.40.50.720 2 154 6.1E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 147 209 4.6E-7 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 Gene3D G3DSA:3.30.360.10 155 291 2.4E-29 T 09-03-2017 ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 Gene3D G3DSA:3.30.360.10 341 388 2.4E-29 T 09-03-2017 ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 125 1.0E-21 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS14615 a658435d324fbcc9c9df4921e05336f6 395 SUPERFAMILY SSF55347 141 309 1.14E-26 T 09-03-2017 ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 Gene3D G3DSA:3.90.1150.10 254 386 3.6E-48 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 Gene3D G3DSA:3.40.640.10 8 252 1.1E-94 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 SUPERFAMILY SSF53383 10 386 4.3E-115 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 383 5.7E-141 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 PIRSF PIRSF001434 1 387 2.7E-140 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS03090 71796f863aad920b8b53f89bd88508a9 389 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Gene3D G3DSA:3.10.350.10 229 276 2.6E-17 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Gene3D G3DSA:3.10.350.10 89 134 2.8E-14 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Gene3D G3DSA:3.10.350.10 158 203 5.4E-18 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SUPERFAMILY SSF53955 323 446 9.7E-26 T 09-03-2017 IPR023346 Lysozyme-like domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SUPERFAMILY SSF54106 89 134 3.66E-9 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Pfam PF01464 Transglycosylase SLT domain 333 436 1.4E-17 T 09-03-2017 IPR008258 Transglycosylase SLT domain 1 ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SMART SM00257 90 134 3.1E-12 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SMART SM00257 231 275 8.8E-16 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SMART SM00257 159 203 9.1E-17 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SUPERFAMILY SSF54106 158 203 2.22E-11 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Gene3D G3DSA:1.10.530.10 324 447 8.0E-26 T 09-03-2017 ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 SUPERFAMILY SSF54106 230 275 1.12E-10 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Pfam PF01476 LysM domain 232 275 8.1E-15 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Pfam PF01476 LysM domain 91 133 1.7E-10 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS10920 8466756a61bb575c6446da4deee93fb4 449 Pfam PF01476 LysM domain 160 203 5.5E-14 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 SUPERFAMILY SSF51905 3 154 4.92E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 SUPERFAMILY SSF51905 279 357 4.92E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 Pfam PF01613 Flavin reductase like domain 423 566 4.0E-37 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 7.1E-5 T 09-03-2017 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 7.1E-5 T 09-03-2017 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.1E-5 T 09-03-2017 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 Gene3D G3DSA:2.30.110.10 412 564 5.6E-58 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 Gene3D G3DSA:3.40.50.720 110 173 1.7E-8 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 Gene3D G3DSA:3.40.50.720 2 35 1.7E-8 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 SMART SM00903 422 565 2.3E-62 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS17480 e9978de75268c2d83ddc11db5c0c6de1 572 SUPERFAMILY SSF50475 413 565 5.4E-50 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 Gene3D G3DSA:3.40.140.10 13 158 3.0E-32 T 09-03-2017 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 SUPERFAMILY SSF53927 14 151 2.51E-40 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 110 1.5E-20 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 Gene3D G3DSA:3.40.430.10 159 348 1.5E-55 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 99 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 Pfam PF01872 RibD C-terminal domain 157 325 1.4E-39 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 SUPERFAMILY SSF53597 157 347 1.83E-46 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS10335 61cd177424a7534babb987d9422646da 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 25 329 1.2E-78 T 09-03-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 3.6E-7 T 09-03-2017 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.6E-7 T 09-03-2017 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.6E-7 T 09-03-2017 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 SUPERFAMILY SSF51905 11 221 4.27E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 Gene3D G3DSA:3.50.50.60 120 356 2.7E-25 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 349 1.6E-41 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 Gene3D G3DSA:3.50.50.60 10 119 2.6E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13100 5ad967116f01072726851baac5677fa1 483 SUPERFAMILY SSF51905 173 327 3.24E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 SMART SM00938 4 105 9.3E-53 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.5E-34 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 Gene3D G3DSA:3.30.70.120 1 112 1.9E-40 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 09-03-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 SUPERFAMILY SSF54913 1 112 2.19E-37 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 PRINTS PR00340 P-II protein signature 23 41 3.0E-32 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 PRINTS PR00340 P-II protein signature 2 17 3.0E-32 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 PRINTS PR00340 P-II protein signature 83 103 3.0E-32 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS06965 249a9b7bd2033f96ac51c80a8beeb65f 112 PRINTS PR00340 P-II protein signature 52 75 3.0E-32 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Gene3D G3DSA:3.40.50.980 46 207 1.1E-28 T 09-03-2017 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Pfam PF00501 AMP-binding enzyme 49 444 1.0E-72 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 SUPERFAMILY SSF56801 29 544 1.83E-124 T 09-03-2017 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 531 2.3E-23 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Gene3D G3DSA:3.40.50.980 208 360 3.3E-28 T 09-03-2017 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Gene3D G3DSA:2.30.38.10 363 434 1.3E-12 T 09-03-2017 ARZXY2_RS09430 5aae532332d58864d0789af74d286b8d 566 Gene3D G3DSA:3.30.300.30 441 544 4.7E-29 T 09-03-2017 ARZXY2_RS15390 ae4d71ad87f0039f6c5be2dac56a4811 304 SUPERFAMILY SSF56059 108 280 3.7E-25 T 09-03-2017 ARZXY2_RS15390 ae4d71ad87f0039f6c5be2dac56a4811 304 Gene3D G3DSA:3.30.1490.20 118 188 7.0E-8 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS15390 ae4d71ad87f0039f6c5be2dac56a4811 304 Pfam PF02655 ATP-grasp domain 106 278 1.8E-11 T 09-03-2017 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 ARZXY2_RS15390 ae4d71ad87f0039f6c5be2dac56a4811 304 Gene3D G3DSA:3.40.50.20 3 115 9.2E-14 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS15390 ae4d71ad87f0039f6c5be2dac56a4811 304 Gene3D G3DSA:3.30.470.20 207 283 2.0E-9 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS14705 ab22cb6d9fc3fe21de527c0b71d4accc 153 Gene3D G3DSA:1.10.10.410 93 152 6.4E-19 T 09-03-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal ARZXY2_RS14705 ab22cb6d9fc3fe21de527c0b71d4accc 153 SUPERFAMILY SSF89095 1 152 1.99E-32 T 09-03-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 ARZXY2_RS14705 ab22cb6d9fc3fe21de527c0b71d4accc 153 Pfam PF09424 Yqey-like protein 4 152 1.5E-37 T 09-03-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial ARZXY2_RS14705 ab22cb6d9fc3fe21de527c0b71d4accc 153 Gene3D G3DSA:1.10.1510.10 1 92 4.1E-23 T 09-03-2017 ARZXY2_RS01120 6de54e697a194253d60c27abc5a7803f 260 Gene3D G3DSA:3.10.180.10 144 255 2.8E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01120 6de54e697a194253d60c27abc5a7803f 260 Gene3D G3DSA:3.10.180.10 12 131 2.8E-26 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01120 6de54e697a194253d60c27abc5a7803f 260 SUPERFAMILY SSF54593 144 258 9.8E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS01120 6de54e697a194253d60c27abc5a7803f 260 SUPERFAMILY SSF54593 14 196 3.49E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS10625 c289820cdf610fe62f43661814b772ed 534 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 493 2.3E-156 T 09-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 Gene3D G3DSA:2.30.250.10 90 217 1.4E-33 T 09-03-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 17 429 2.9E-116 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 SUPERFAMILY SSF53187 8 90 1.3E-97 T 09-03-2017 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 SUPERFAMILY SSF53187 211 429 1.3E-97 T 09-03-2017 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 Gene3D G3DSA:3.40.630.10 220 430 8.4E-109 T 09-03-2017 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 Gene3D G3DSA:3.40.630.10 9 89 8.4E-109 T 09-03-2017 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 SUPERFAMILY SSF101821 91 209 6.13E-27 T 09-03-2017 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 264 282 2.9E-36 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 307 323 2.9E-36 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 396 411 2.9E-36 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 79 95 2.9E-36 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS18745 a5cae3da3f7abeef6886880912d9932a 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 112 132 2.9E-36 T 09-03-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SUPERFAMILY SSF81624 2 78 5.23E-24 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SUPERFAMILY SSF81624 108 153 5.23E-24 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 Gene3D G3DSA:3.20.190.10 2 76 1.5E-14 T 09-03-2017 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 Gene3D G3DSA:3.20.190.10 110 152 1.5E-14 T 09-03-2017 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 Gene3D G3DSA:1.10.8.50 153 294 1.9E-39 T 09-03-2017 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 Pfam PF06827 Zinc finger found in FPG and IleRS 267 294 2.8E-5 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 152 238 1.1E-16 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SMART SM01232 152 245 6.9E-28 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SUPERFAMILY SSF57716 259 294 1.02E-9 T 09-03-2017 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SMART SM00898 2 138 1.6E-19 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 ARZXY2_RS07570 5afbf96503220faec0fdecf9d82ad915 295 SUPERFAMILY SSF46946 151 235 3.39E-23 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 ARZXY2_RS16960 4c8bcc0696b22161250c346563974b1a 289 SUPERFAMILY SSF51621 2 236 3.85E-46 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS16960 4c8bcc0696b22161250c346563974b1a 289 PIRSF PIRSF015582 1 289 2.7E-57 T 09-03-2017 IPR011206 Citrate lyase beta subunit-like ARZXY2_RS16960 4c8bcc0696b22161250c346563974b1a 289 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 226 1.4E-33 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS16960 4c8bcc0696b22161250c346563974b1a 289 Gene3D G3DSA:3.20.20.60 2 236 2.5E-53 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 SUPERFAMILY SSF88659 122 184 6.73E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 Gene3D G3DSA:1.10.1740.10 13 118 1.4E-15 T 09-03-2017 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 Pfam PF04542 Sigma-70 region 2 34 96 6.4E-8 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 SUPERFAMILY SSF88946 12 109 1.3E-14 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 184 1.4E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15295 3d7177ceb97cd430eacbbea31af5ac05 261 Gene3D G3DSA:1.10.10.10 129 184 3.7E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 SUPERFAMILY SSF53474 29 311 2.2E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00412 Epoxide hydrolase signature 125 138 7.1E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00412 Epoxide hydrolase signature 79 94 7.1E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00412 Epoxide hydrolase signature 286 308 7.1E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00412 Epoxide hydrolase signature 253 269 7.1E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 Pfam PF00561 alpha/beta hydrolase fold 56 296 3.5E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 Gene3D G3DSA:3.40.50.1820 22 310 1.4E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 3.7E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 94 3.7E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS08190 037f9c5cfd59e28aa22c6ab90cd2d13a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 139 152 3.7E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 PIRSF PIRSF002888 2 294 4.0E-65 T 09-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 Pfam PF02154 Flagellar motor switch protein FliM 14 195 3.6E-32 T 09-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 SUPERFAMILY SSF103039 22 185 1.1E-10 T 09-03-2017 IPR028976 CheC-like domain ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 220 284 7.9E-12 T 09-03-2017 IPR001543 Surface presentation of antigen (SpoA) ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 SUPERFAMILY SSF101801 218 289 6.02E-12 T 09-03-2017 IPR001543 Surface presentation of antigen (SpoA) ARZXY2_RS14470 a1651246a4bd4c65cd0a7af3ffeb155c 294 Gene3D G3DSA:2.30.330.10 219 280 1.4E-9 T 09-03-2017 ARZXY2_RS12640 7ac59facf43e17e37c71ade9cb1fc1a5 351 SUPERFAMILY SSF53474 200 343 7.29E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12640 7ac59facf43e17e37c71ade9cb1fc1a5 351 SUPERFAMILY SSF53474 9 165 7.29E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12640 7ac59facf43e17e37c71ade9cb1fc1a5 351 Gene3D G3DSA:3.40.50.1820 11 344 3.1E-38 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 Gene3D G3DSA:1.10.390.10 315 462 3.4E-40 T 09-03-2017 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 SUPERFAMILY SSF55486 214 460 3.22E-75 T 09-03-2017 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 SUPERFAMILY SSF63737 12 201 2.62E-39 T 09-03-2017 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 Pfam PF11838 ERAP1-like C-terminal domain 532 843 3.6E-55 T 09-03-2017 IPR024571 ERAP1-like C-terminal domain ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 849 0.0 T 09-03-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 268 278 1.2E-20 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 1.2E-20 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 1.2E-20 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 1.2E-20 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 131 146 1.2E-20 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS07555 95af9416b217733bdabd3e33d598d1e2 853 Pfam PF01433 Peptidase family M1 19 394 7.3E-72 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 ARZXY2_RS02070 d162ac5ba80d5623bce7156925a4da71 510 Pfam PF01547 Bacterial extracellular solute-binding protein 54 362 1.5E-19 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS02070 d162ac5ba80d5623bce7156925a4da71 510 SUPERFAMILY SSF53850 22 508 2.36E-90 T 09-03-2017 ARZXY2_RS02070 d162ac5ba80d5623bce7156925a4da71 510 Gene3D G3DSA:3.40.190.10 457 508 8.5E-62 T 09-03-2017 ARZXY2_RS02070 d162ac5ba80d5623bce7156925a4da71 510 Gene3D G3DSA:3.40.190.10 152 367 8.5E-62 T 09-03-2017 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 SMART SM00420 6 58 4.6E-17 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.2E-15 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 Gene3D G3DSA:1.10.10.10 5 71 4.8E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 SUPERFAMILY SSF46785 4 58 3.83E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 Pfam PF00455 DeoR C terminal sensor domain 77 242 3.6E-43 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 Gene3D G3DSA:3.40.50.1360 77 225 8.7E-10 T 09-03-2017 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 SUPERFAMILY SSF100950 77 243 6.7E-26 T 09-03-2017 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 SMART SM01134 74 243 6.1E-61 T 09-03-2017 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.8E-9 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.8E-9 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS17225 fddafad545effc579f6af5ca9032b810 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ARZXY2_RS14860 77ff4f78167aaa44b75888befab051b3 152 Pfam PF00545 ribonuclease 68 146 8.3E-25 T 09-03-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 ARZXY2_RS14860 77ff4f78167aaa44b75888befab051b3 152 Gene3D G3DSA:3.10.450.30 60 150 1.6E-34 T 09-03-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 ARZXY2_RS14860 77ff4f78167aaa44b75888befab051b3 152 SUPERFAMILY SSF53933 59 148 2.3E-30 T 09-03-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 ARZXY2_RS19490 2ce53f3ff2c0df4fb831b87031ca07d4 136 Pfam PF02467 Transcription factor WhiB 15 82 4.0E-23 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS19490 2ce53f3ff2c0df4fb831b87031ca07d4 136 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 88 17.468 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS00870 221b4dd1cab0f05973c6df08fa266076 297 Gene3D G3DSA:3.40.50.970 5 292 4.7E-100 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS00870 221b4dd1cab0f05973c6df08fa266076 297 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 288 4.1E-49 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS00870 221b4dd1cab0f05973c6df08fa266076 297 SUPERFAMILY SSF52518 11 291 6.33E-84 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 Pfam PF02223 Thymidylate kinase 12 198 1.7E-48 T 09-03-2017 ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 ProSitePatterns PS01331 Thymidylate kinase signature. 97 109 - T 09-03-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 SUPERFAMILY SSF52540 6 205 1.24E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 Hamap MF_00165 Thymidylate kinase [tmk]. 8 210 29.328 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 7 199 4.3E-51 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 ARZXY2_RS14945 5594b798d88fe520dbc2a5008b0801a8 216 Gene3D G3DSA:3.40.50.300 7 210 5.4E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 Gene3D G3DSA:3.20.20.140 77 419 4.5E-131 T 09-03-2017 ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 Pfam PF01979 Amidohydrolase family 58 432 2.8E-34 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 SUPERFAMILY SSF51556 62 380 9.36E-102 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 SUPERFAMILY SSF51338 8 61 2.0E-19 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 SUPERFAMILY SSF51338 380 434 2.0E-19 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 TIGRFAM TIGR03178 allantoinase: allantoinase 9 437 1.8E-169 T 09-03-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 ARZXY2_RS01220 7a1fe677b4124ec444ecc1588d776cc0 449 Gene3D G3DSA:2.30.40.10 9 76 5.6E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS08560 062a6ae32740d34be624356a4639fb23 137 Gene3D G3DSA:3.10.450.50 3 128 3.3E-11 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS08560 062a6ae32740d34be624356a4639fb23 137 SUPERFAMILY SSF54427 1 129 1.62E-13 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS08560 062a6ae32740d34be624356a4639fb23 137 Pfam PF12680 SnoaL-like domain 15 124 2.8E-10 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS16905 6d2f18ec7085472b9f2cc94d98315735 385 Gene3D G3DSA:3.30.360.10 151 362 2.4E-40 T 09-03-2017 ARZXY2_RS16905 6d2f18ec7085472b9f2cc94d98315735 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 133 9.3E-24 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS16905 6d2f18ec7085472b9f2cc94d98315735 385 SUPERFAMILY SSF51735 5 162 3.58E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16905 6d2f18ec7085472b9f2cc94d98315735 385 Gene3D G3DSA:3.40.50.720 8 150 7.6E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16905 6d2f18ec7085472b9f2cc94d98315735 385 SUPERFAMILY SSF55347 141 297 6.98E-21 T 09-03-2017 ARZXY2_RS06740 bb210fc7eddf02f5b10ea3267045f080 660 Pfam PF00589 Phage integrase family 310 493 1.9E-9 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06740 bb210fc7eddf02f5b10ea3267045f080 660 SUPERFAMILY SSF56349 297 503 2.85E-18 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06740 bb210fc7eddf02f5b10ea3267045f080 660 Gene3D G3DSA:1.10.443.10 306 500 4.7E-18 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS05005 78c3900b8df1e4acc93ba604606dbe23 469 Gene3D G3DSA:3.90.1150.10 303 424 1.7E-9 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS05005 78c3900b8df1e4acc93ba604606dbe23 469 SUPERFAMILY SSF53383 48 425 7.66E-75 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS05005 78c3900b8df1e4acc93ba604606dbe23 469 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 236 255 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ARZXY2_RS05005 78c3900b8df1e4acc93ba604606dbe23 469 Pfam PF00266 Aminotransferase class-V 52 417 3.7E-75 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS05005 78c3900b8df1e4acc93ba604606dbe23 469 Gene3D G3DSA:3.40.640.10 66 302 1.4E-56 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 402 2.1E-226 T 09-03-2017 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 1.1E-26 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 SUPERFAMILY SSF51735 172 362 8.01E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 SUPERFAMILY SSF50129 4 196 3.25E-57 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 Gene3D G3DSA:3.90.180.10 5 240 7.0E-72 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS16475 6b60c18f380d9c47b0d6cd1bfd4f915f 405 Pfam PF00107 Zinc-binding dehydrogenase 206 273 1.4E-7 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 Gene3D G3DSA:1.20.120.530 95 221 6.6E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.9E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.9E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 Gene3D G3DSA:1.10.10.10 3 63 2.3E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 SMART SM00345 7 70 3.8E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 Pfam PF07729 FCD domain 95 217 1.4E-19 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 SUPERFAMILY SSF48008 94 220 1.23E-23 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 63 7.6E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 SMART SM00895 95 218 1.2E-17 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS01955 be26177e568bc980cdbff55830393b6b 232 SUPERFAMILY SSF46785 3 63 1.18E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13540 5e4d4ea861bfaaed85881f66b01dc94e 205 SUPERFAMILY SSF55166 70 172 4.19E-19 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 ARZXY2_RS13540 5e4d4ea861bfaaed85881f66b01dc94e 205 Gene3D G3DSA:3.30.1380.10 82 181 2.5E-20 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 ARZXY2_RS13540 5e4d4ea861bfaaed85881f66b01dc94e 205 Pfam PF08291 Peptidase M15 86 171 9.6E-16 T 09-03-2017 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 Pfam PF07676 WD40-like Beta Propeller Repeat 57 89 5.4E-8 T 09-03-2017 IPR011659 WD40-like Beta Propeller ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 Pfam PF00326 Prolyl oligopeptidase family 457 662 1.9E-49 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 SUPERFAMILY SSF82171 10 125 5.76E-32 T 09-03-2017 ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 SUPERFAMILY SSF82171 165 388 5.76E-32 T 09-03-2017 ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 Gene3D G3DSA:2.120.10.30 10 156 4.1E-41 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 Gene3D G3DSA:2.120.10.30 200 313 4.1E-41 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 SUPERFAMILY SSF53474 415 662 4.89E-64 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08570 14d0ce45ae9a40c64e38d24f8468d542 683 Gene3D G3DSA:3.40.50.1820 414 662 1.7E-62 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 16 258 9.3E-84 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 SUPERFAMILY SSF63829 10 290 2.62E-70 T 09-03-2017 ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 157 177 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 197 214 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 239 257 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 134 156 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 17 34 6.3E-46 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS19255 5a3771fad9ffb7c6cc9bafd9c93c6a8d 292 Gene3D G3DSA:2.120.10.30 7 292 7.5E-96 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS19020 167f146881cb21412815eff1e8ac578b 211 SUPERFAMILY SSF51569 4 209 2.38E-56 T 09-03-2017 ARZXY2_RS19020 167f146881cb21412815eff1e8ac578b 211 Pfam PF01081 KDPG and KHG aldolase 10 200 2.6E-43 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS19020 167f146881cb21412815eff1e8ac578b 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 203 5.1E-54 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 ARZXY2_RS19020 167f146881cb21412815eff1e8ac578b 211 Gene3D G3DSA:3.20.20.70 3 210 5.6E-68 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 9.7E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 9.7E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 SMART SM00345 5 64 5.1E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 SUPERFAMILY SSF48008 86 215 2.88E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 SUPERFAMILY SSF46785 3 68 1.17E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 Gene3D G3DSA:1.10.10.10 2 68 1.5E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 Pfam PF07729 FCD domain 87 208 2.8E-26 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 4.3E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 SMART SM00895 87 209 1.8E-23 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19195 e5336a8f618ecf7eaa59cb0711933848 227 Gene3D G3DSA:1.20.120.530 86 220 3.2E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 Gene3D G3DSA:1.10.260.40 1 52 3.5E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 SUPERFAMILY SSF47413 2 55 4.13E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 Pfam PF13377 Periplasmic binding protein-like domain 168 329 5.4E-35 T 09-03-2017 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 47 5.0E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 SUPERFAMILY SSF53822 61 334 4.12E-61 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 Gene3D G3DSA:3.40.50.2300 53 171 2.4E-25 T 09-03-2017 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 Gene3D G3DSA:3.40.50.2300 172 308 9.6E-44 T 09-03-2017 ARZXY2_RS16715 d1e17fe7e856a0e2fcafeaaf9d4743bb 343 SMART SM00354 1 70 6.9E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS07900 d482c109229a59df278e03a38c747a33 179 Gene3D G3DSA:1.10.357.10 3 178 6.2E-25 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS07900 d482c109229a59df278e03a38c747a33 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 3.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS07900 d482c109229a59df278e03a38c747a33 179 SUPERFAMILY SSF46689 3 66 1.8E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Gene3D G3DSA:2.30.30.30 120 196 1.1E-31 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 SUPERFAMILY SSF50249 3 126 5.83E-50 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.5E-33 T 09-03-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 SMART SM01383 42 119 2.9E-41 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 3.5E-54 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 SUPERFAMILY SSF50104 127 271 2.77E-55 T 09-03-2017 IPR008991 Translation protein SH3-like domain ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 09-03-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.398 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Gene3D G3DSA:4.10.950.10 197 273 2.0E-30 T 09-03-2017 IPR014726 Ribosomal protein L2, domain 3 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 5.7E-127 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 Gene3D G3DSA:2.40.50.140 1 115 3.8E-51 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 PIRSF PIRSF002158 3 275 4.4E-94 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03510 6bcb260b77969a6e88e85b53b72b275e 279 SMART SM01382 125 253 4.4E-88 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 SUPERFAMILY SSF47413 4 65 1.73E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 Gene3D G3DSA:3.40.50.2300 182 319 1.0E-47 T 09-03-2017 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 54 2.0E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 Gene3D G3DSA:3.40.50.2300 60 181 4.8E-29 T 09-03-2017 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 09-03-2017 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 SUPERFAMILY SSF53822 68 345 1.11E-63 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 SMART SM00354 5 77 8.8E-27 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 Pfam PF13377 Periplasmic binding protein-like domain 178 341 1.1E-35 T 09-03-2017 ARZXY2_RS19825 3ac7c4a0b4fc30f4e49f24603ca9fee1 346 Gene3D G3DSA:1.10.260.40 7 59 5.7E-25 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS12830 98c6565b130d3cbbbd44b0d0daac1ebf 824 SUPERFAMILY SSF54001 421 576 4.42E-35 T 09-03-2017 ARZXY2_RS12830 98c6565b130d3cbbbd44b0d0daac1ebf 824 Pfam PF13559 Domain of unknown function (DUF4129) 682 751 3.0E-7 T 09-03-2017 IPR025403 Domain of unknown function DUF4129 ARZXY2_RS12830 98c6565b130d3cbbbd44b0d0daac1ebf 824 Gene3D G3DSA:3.90.260.10 440 576 3.5E-22 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS12830 98c6565b130d3cbbbd44b0d0daac1ebf 824 Pfam PF01841 Transglutaminase-like superfamily 442 571 2.5E-24 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS12830 98c6565b130d3cbbbd44b0d0daac1ebf 824 SMART SM00460 493 573 3.4E-17 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 Gene3D G3DSA:3.90.226.10 48 252 9.2E-62 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 Gene3D G3DSA:1.10.12.10 254 303 4.1E-28 T 09-03-2017 IPR014748 Crontonase, C-terminal ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 Pfam PF00378 Enoyl-CoA hydratase/isomerase 50 309 2.6E-49 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 18 314 52.794 T 09-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 152 172 - T 09-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 SUPERFAMILY SSF52096 48 312 9.95E-71 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS02220 d2f2cb71097481b4b8e404ba24e29375 315 TIGRFAM TIGR01929 menB: naphthoate synthase 48 311 1.1E-116 T 09-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 312 685 1.5E-54 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 SUPERFAMILY SSF51445 2 310 3.16E-78 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 PRINTS PR00133 Glycosyl hydrolase family 3 signature 106 122 1.5E-28 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 PRINTS PR00133 Glycosyl hydrolase family 3 signature 31 47 1.5E-28 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 PRINTS PR00133 Glycosyl hydrolase family 3 signature 137 153 1.5E-28 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 PRINTS PR00133 Glycosyl hydrolase family 3 signature 207 225 1.5E-28 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 PRINTS PR00133 Glycosyl hydrolase family 3 signature 60 79 1.5E-28 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 49 273 2.8E-47 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 207 224 - T 09-03-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Pfam PF14310 Fibronectin type III-like domain 720 773 1.8E-7 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 SMART SM01217 720 786 0.0014 T 09-03-2017 IPR026891 Fibronectin type III-like domain ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Gene3D G3DSA:3.40.50.1700 301 379 6.7E-64 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Gene3D G3DSA:3.40.50.1700 533 687 6.7E-64 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 Gene3D G3DSA:3.20.20.300 28 284 1.1E-85 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 SUPERFAMILY SSF52279 533 688 2.09E-48 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS07270 d87bb88da7a152e5fc7b1adb93e1f0b8 801 SUPERFAMILY SSF52279 312 381 2.09E-48 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 Gene3D G3DSA:2.60.120.560 414 455 3.0E-4 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 Gene3D G3DSA:2.60.120.560 330 368 6.9E-5 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 Gene3D G3DSA:2.115.10.20 19 159 2.8E-11 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 SUPERFAMILY SSF75005 17 356 2.36E-73 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 25 38 - T 09-03-2017 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 25 355 2.0E-57 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 SMART SM00640 25 431 5.4E-48 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS02755 b53dc49583f38b2ac167edb5c4e7a343 465 Gene3D G3DSA:2.115.10.20 160 254 7.6E-6 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.1E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.1E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 Gene3D G3DSA:3.40.50.720 3 203 1.1E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.2E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 Pfam PF00106 short chain dehydrogenase 9 193 6.2E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 SUPERFAMILY SSF51735 6 249 1.85E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17370 0a40758b9a45ca7adff797060be042da 261 PIRSF PIRSF000126 1 251 2.3E-62 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS05280 97a2f8aee7ea431bf67c25e5992a3bda 838 Gene3D G3DSA:1.20.1540.10 32 211 1.6E-5 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ARZXY2_RS05280 97a2f8aee7ea431bf67c25e5992a3bda 838 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 504 803 5.3E-94 T 09-03-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal ARZXY2_RS05280 97a2f8aee7ea431bf67c25e5992a3bda 838 SUPERFAMILY SSF144091 30 211 5.75E-8 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 Gene3D G3DSA:1.20.272.10 218 336 6.6E-14 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 SUPERFAMILY SSF48019 222 336 9.35E-20 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 Gene3D G3DSA:1.10.8.60 140 217 3.4E-19 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 Gene3D G3DSA:3.40.50.300 2 139 1.4E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 PRINTS PR01217 Proline rich extensin signature 867 892 2.2E-9 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 PRINTS PR01217 Proline rich extensin signature 832 849 2.2E-9 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 PRINTS PR01217 Proline rich extensin signature 718 734 2.2E-9 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 PRINTS PR01217 Proline rich extensin signature 776 797 2.2E-9 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 PRINTS PR01217 Proline rich extensin signature 703 715 2.2E-9 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 SMART SM00382 9 157 2.0E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 Pfam PF13177 DNA polymerase III, delta subunit 3 150 5.8E-35 T 09-03-2017 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 213 337 2.5E-14 T 09-03-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 335 1.1E-104 T 09-03-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 ARZXY2_RS15800 bc41782c31c5ad3a48c7109424ff6b87 1156 SUPERFAMILY SSF52540 4 195 1.84E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18725 cf3d4c0d9522a037a3eb246dafc82f53 315 SMART SM00382 26 204 4.4E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS18725 cf3d4c0d9522a037a3eb246dafc82f53 315 Pfam PF00005 ABC transporter 19 156 2.4E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS18725 cf3d4c0d9522a037a3eb246dafc82f53 315 Gene3D G3DSA:3.40.50.300 1 229 2.0E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18725 cf3d4c0d9522a037a3eb246dafc82f53 315 SUPERFAMILY SSF52540 2 231 5.92E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05735 cf4a32a66278baf646f46222de4334a1 539 SUPERFAMILY SSF52540 40 104 2.13E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05735 cf4a32a66278baf646f46222de4334a1 539 SUPERFAMILY SSF52540 131 239 2.13E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05735 cf4a32a66278baf646f46222de4334a1 539 Gene3D G3DSA:3.40.50.300 48 247 3.4E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05735 cf4a32a66278baf646f46222de4334a1 539 Pfam PF01926 50S ribosome-binding GTPase 59 180 2.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 SUPERFAMILY SSF52922 189 323 3.93E-36 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 SMART SM00861 3 178 1.5E-59 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 SUPERFAMILY SSF52518 3 184 3.93E-63 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 175 8.3E-39 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 Pfam PF02780 Transketolase, C-terminal domain 194 314 1.6E-34 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 Gene3D G3DSA:3.40.50.920 197 320 1.4E-40 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS09900 bda4138942608afd316940c779a95adc 325 Gene3D G3DSA:3.40.50.970 2 190 9.9E-72 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 149 294 1.1E-6 T 09-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Gene3D G3DSA:3.40.50.720 94 148 3.7E-4 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Gene3D G3DSA:3.40.50.720 4 93 4.0E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 SMART SM00846 4 141 2.9E-13 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 353 144.266 T 09-03-2017 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Gene3D G3DSA:3.30.360.10 149 303 1.9E-23 T 09-03-2017 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 9.3E-9 T 09-03-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 337 2.6E-92 T 09-03-2017 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 SUPERFAMILY SSF51735 5 155 1.8E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 PIRSF PIRSF000149 2 321 1.9E-48 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 SUPERFAMILY SSF55347 140 305 3.92E-35 T 09-03-2017 ARZXY2_RS06095 d7e0bc79dfa554207f257d55ec145fc9 353 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 09-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS08260 8f91e6500116d191cd62f7914ddcb459 409 Pfam PF04055 Radical SAM superfamily 34 211 1.8E-22 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS08260 8f91e6500116d191cd62f7914ddcb459 409 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 371 8.5E-73 T 09-03-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 ARZXY2_RS08260 8f91e6500116d191cd62f7914ddcb459 409 SMART SM00729 29 257 8.6E-54 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS08260 8f91e6500116d191cd62f7914ddcb459 409 Gene3D G3DSA:3.80.30.20 32 271 4.0E-37 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe ARZXY2_RS08260 8f91e6500116d191cd62f7914ddcb459 409 SUPERFAMILY SSF102114 24 407 5.62E-104 T 09-03-2017 ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SMART SM00487 273 483 9.9E-31 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Pfam PF00270 DEAD/DEAH box helicase 299 459 1.6E-15 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Gene3D G3DSA:2.40.50.140 45 144 1.2E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Pfam PF00271 Helicase conserved C-terminal domain 558 639 1.6E-15 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SUPERFAMILY SSF52540 193 476 6.23E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SMART SM00490 553 639 8.1E-19 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SUPERFAMILY SSF52540 415 520 2.3E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SUPERFAMILY SSF52540 550 650 2.3E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Pfam PF17191 RecG wedge domain 12 182 3.4E-9 T 09-03-2017 IPR033454 RecG, wedge domain ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Gene3D G3DSA:3.40.50.300 479 687 2.0E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 Gene3D G3DSA:3.40.50.300 264 478 1.4E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05795 61a1dfb6e734f274320b1aae04c19ac9 751 SUPERFAMILY SSF50249 11 186 3.26E-19 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 SUPERFAMILY SSF46785 9 89 6.54E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.0E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.0E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.0E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 Gene3D G3DSA:3.40.190.10 193 272 2.6E-7 T 09-03-2017 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 5.6E-19 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 Gene3D G3DSA:3.40.190.10 123 192 1.8E-4 T 09-03-2017 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 Gene3D G3DSA:1.10.10.10 8 87 8.3E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 SUPERFAMILY SSF53850 108 302 1.15E-19 T 09-03-2017 ARZXY2_RS10195 675e43064be33558517e06489fb96d6e 313 Pfam PF03466 LysR substrate binding domain 126 303 6.9E-8 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 3 236 6.4E-58 T 09-03-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 Gene3D G3DSA:3.10.290.10 3 91 6.2E-20 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 Pfam PF01728 FtsJ-like methyltransferase 59 239 1.3E-15 T 09-03-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 SMART SM00363 2 68 5.2E-6 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 PIRSF PIRSF005578 1 260 2.2E-86 T 09-03-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 Pfam PF01479 S4 domain 3 45 3.6E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 Gene3D G3DSA:3.40.50.150 92 131 4.2E-4 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 SUPERFAMILY SSF55174 3 60 9.71E-9 T 09-03-2017 ARZXY2_RS11130 639c8661f978567130cbedf14ea0f07e 270 SUPERFAMILY SSF53335 54 244 3.49E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS19815 46353a12a18712ce7982ccee8c53df20 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS19815 46353a12a18712ce7982ccee8c53df20 315 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS19815 46353a12a18712ce7982ccee8c53df20 315 Pfam PF00294 pfkB family carbohydrate kinase 16 298 5.8E-31 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS19815 46353a12a18712ce7982ccee8c53df20 315 SUPERFAMILY SSF53613 14 301 4.83E-56 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS19815 46353a12a18712ce7982ccee8c53df20 315 Gene3D G3DSA:3.40.1190.20 15 305 5.5E-56 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 255 2.6E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 SUPERFAMILY SSF51735 7 271 2.8E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 271 3.1E-35 T 09-03-2017 ARZXY2_RS13905 0bc93fd29939cd9101ac326c1344440b 275 Gene3D G3DSA:3.40.50.720 5 272 2.4E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Gene3D G3DSA:1.10.287.110 3 99 1.4E-32 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SUPERFAMILY SSF49493 211 253 1.01E-16 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SUPERFAMILY SSF49493 108 146 1.01E-16 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Gene3D G3DSA:2.60.260.20 257 332 1.0E-17 T 09-03-2017 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Gene3D G3DSA:2.60.260.20 109 137 1.5E-19 T 09-03-2017 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Gene3D G3DSA:2.60.260.20 211 252 1.5E-19 T 09-03-2017 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 371 35.741 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SUPERFAMILY SSF49493 257 342 9.81E-20 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Pfam PF00684 DnaJ central domain 141 205 5.0E-10 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SUPERFAMILY SSF57938 128 208 1.15E-16 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 44 63 - T 09-03-2017 IPR018253 DnaJ domain, conserved site ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Gene3D G3DSA:2.10.230.10 138 208 6.0E-18 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Pfam PF01556 DnaJ C terminal domain 116 331 1.7E-35 T 09-03-2017 IPR002939 Chaperone DnaJ, C-terminal ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 Pfam PF00226 DnaJ domain 4 64 3.0E-25 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 347 1.9E-114 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SMART SM00271 2 59 9.8E-28 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 SUPERFAMILY SSF46565 3 103 2.09E-33 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 PRINTS PR00625 DnaJ domain signature 59 78 3.3E-25 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 PRINTS PR00625 DnaJ domain signature 5 23 3.3E-25 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 PRINTS PR00625 DnaJ domain signature 39 59 3.3E-25 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08280 4f257968db46fa16dcc816486b22a5a7 375 PRINTS PR00625 DnaJ domain signature 23 38 3.3E-25 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS08575 23bfa3076a2a7e237678fea9f0040bb2 284 Pfam PF13649 Methyltransferase domain 96 179 8.4E-10 T 09-03-2017 ARZXY2_RS08575 23bfa3076a2a7e237678fea9f0040bb2 284 Gene3D G3DSA:3.40.50.150 80 199 1.4E-19 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08575 23bfa3076a2a7e237678fea9f0040bb2 284 SUPERFAMILY SSF53335 31 263 2.62E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08575 23bfa3076a2a7e237678fea9f0040bb2 284 PIRSF PIRSF018249 1 279 3.5E-75 T 09-03-2017 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 2.2E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 402 2.2E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 2.2E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 403 3.9E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 SUPERFAMILY SSF55874 281 403 1.92E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 Gene3D G3DSA:3.30.565.10 308 403 4.4E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 PIRSF PIRSF037434 8 403 1.5E-124 T 09-03-2017 IPR017205 Signal transduction histidine kinase, ChrS ARZXY2_RS16545 7e3c7e563e9b5b8dd54cea93bede93cf 403 Pfam PF07730 Histidine kinase 209 272 1.9E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 Gene3D G3DSA:3.30.420.40 1 245 2.0E-41 T 09-03-2017 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 SUPERFAMILY SSF53067 4 246 4.0E-43 T 09-03-2017 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 434 2.4E-29 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 229 4.8E-37 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 PIRSF PIRSF000538 1 453 1.8E-74 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 Gene3D G3DSA:3.30.420.40 251 434 2.5E-30 T 09-03-2017 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 TIGRFAM TIGR01312 XylB: xylulokinase 6 438 9.5E-115 T 09-03-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 SUPERFAMILY SSF53067 251 468 9.58E-42 T 09-03-2017 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 348 369 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00245 e1f735e90d53d5205cfe08541c7cc9a7 474 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 129 141 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS17250 4267691a890fc0b6a33398cf3e2dcb60 40 SUPERFAMILY SSF55594 1 39 2.88E-8 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17250 4267691a890fc0b6a33398cf3e2dcb60 40 Gene3D G3DSA:3.30.1340.10 1 36 1.6E-8 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17250 4267691a890fc0b6a33398cf3e2dcb60 40 Pfam PF00381 PTS HPr component phosphorylation site 1 35 3.5E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.5E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.5E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.5E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.5E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Pfam PF01018 GTP1/OBG 4 157 1.1E-48 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 342 3.0E-119 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Pfam PF09269 Domain of unknown function (DUF1967) 371 445 2.6E-22 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 SUPERFAMILY SSF102741 369 447 3.4E-18 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 SUPERFAMILY SSF82051 4 157 6.02E-45 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 SUPERFAMILY SSF52540 161 348 8.04E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 371 446 6.3E-26 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Hamap MF_01454 GTPase Obg [obg]. 3 343 42.403 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Gene3D G3DSA:2.70.210.12 3 156 9.6E-47 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Gene3D G3DSA:3.40.50.300 160 352 1.5E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 09-03-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 ARZXY2_RS07680 b2cdfca7094de503ea37a3e4f9a6e4cb 528 Pfam PF01926 50S ribosome-binding GTPase 161 296 1.3E-22 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 169 181 - T 09-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 Gene3D G3DSA:1.20.1250.20 49 225 5.7E-20 T 09-03-2017 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 Gene3D G3DSA:1.20.1250.20 301 487 1.1E-6 T 09-03-2017 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 Pfam PF00854 POT family 108 462 9.5E-61 T 09-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 25 495 1.3E-140 T 09-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 SUPERFAMILY SSF103473 271 488 1.29E-36 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18185 e9a564feded126b8091473af4e88bbac 499 SUPERFAMILY SSF103473 24 224 1.29E-36 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 SUPERFAMILY SSF161098 29 296 3.53E-50 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 Gene3D G3DSA:1.10.3720.10 29 293 1.1E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 296 1.5E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 405 576 1.9E-9 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 Gene3D G3DSA:1.10.3720.10 326 578 6.9E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09635 378f1cedb851d37c02959e9849a72250 584 SUPERFAMILY SSF161098 321 578 1.7E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS06875 c02ce61b5606a8d084dbb3ee7758a61c 163 Gene3D G3DSA:1.10.260.40 9 79 1.5E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS06875 c02ce61b5606a8d084dbb3ee7758a61c 163 SUPERFAMILY SSF47413 9 79 3.58E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS06875 c02ce61b5606a8d084dbb3ee7758a61c 163 SMART SM00530 12 73 2.7E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS06875 c02ce61b5606a8d084dbb3ee7758a61c 163 Pfam PF13560 Helix-turn-helix domain 9 71 6.5E-9 T 09-03-2017 ARZXY2_RS12280 b2c28842df612959edc5770939a8a951 305 SUPERFAMILY SSF53697 5 299 1.31E-46 T 09-03-2017 ARZXY2_RS12280 b2c28842df612959edc5770939a8a951 305 Gene3D G3DSA:3.40.50.10490 172 249 2.8E-19 T 09-03-2017 ARZXY2_RS12280 b2c28842df612959edc5770939a8a951 305 Pfam PF01380 SIS domain 39 158 1.4E-10 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS12280 b2c28842df612959edc5770939a8a951 305 Gene3D G3DSA:3.40.50.10490 7 159 6.2E-23 T 09-03-2017 ARZXY2_RS14460 0dc8217decc8a7c43df42a69e053cbd6 167 Pfam PF04347 Flagellar biosynthesis protein, FliO 22 110 3.7E-18 T 09-03-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 ARZXY2_RS14460 0dc8217decc8a7c43df42a69e053cbd6 167 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 11 78 6.1E-19 T 09-03-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 ARZXY2_RS03570 a42e9e16df8277d7e0931b7311ed0322 127 SUPERFAMILY SSF53137 14 125 1.57E-47 T 09-03-2017 ARZXY2_RS03570 a42e9e16df8277d7e0931b7311ed0322 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 14 127 1.6E-39 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03570 a42e9e16df8277d7e0931b7311ed0322 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 27.469 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03570 a42e9e16df8277d7e0931b7311ed0322 127 Gene3D G3DSA:3.30.420.100 31 126 3.8E-37 T 09-03-2017 ARZXY2_RS03570 a42e9e16df8277d7e0931b7311ed0322 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 5.3E-48 T 09-03-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Gene3D G3DSA:3.90.780.10 953 1142 4.3E-47 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Pfam PF02872 5'-nucleotidase, C-terminal domain 955 1109 1.0E-36 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 SUPERFAMILY SSF56219 330 550 2.49E-30 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 SUPERFAMILY SSF56219 579 608 2.49E-30 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 SUPERFAMILY SSF56219 273 286 2.49E-30 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 SUPERFAMILY SSF56300 609 929 4.18E-62 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Pfam PF00149 Calcineurin-like phosphoesterase 616 839 1.1E-7 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Gene3D G3DSA:3.60.10.10 279 289 6.4E-27 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Gene3D G3DSA:3.60.10.10 321 603 6.4E-27 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Gene3D G3DSA:3.60.21.10 609 926 1.0E-68 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 329 596 7.3E-9 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 PRINTS PR01607 Apyrase family signature 859 879 2.0E-19 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 PRINTS PR01607 Apyrase family signature 822 845 2.0E-19 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 PRINTS PR01607 Apyrase family signature 1004 1027 2.0E-19 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 PRINTS PR01607 Apyrase family signature 1083 1102 2.0E-19 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 PRINTS PR01607 Apyrase family signature 613 631 2.0E-19 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS15050 c62123669be316dc551fe9ed678ae239 1279 SUPERFAMILY SSF55816 929 1143 7.06E-47 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 ARZXY2_RS14095 6c8398a7d328b9b53a1baab34b8fd536 134 Pfam PF14552 Tautomerase enzyme 38 118 7.7E-26 T 09-03-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 ARZXY2_RS14095 6c8398a7d328b9b53a1baab34b8fd536 134 SUPERFAMILY SSF55331 2 128 1.2E-31 T 09-03-2017 IPR014347 Tautomerase/MIF superfamily ARZXY2_RS14095 6c8398a7d328b9b53a1baab34b8fd536 134 Gene3D G3DSA:3.30.429.10 3 125 1.3E-30 T 09-03-2017 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Gene3D G3DSA:3.30.470.30 549 664 7.8E-27 T 09-03-2017 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Gene3D G3DSA:3.30.1490.70 674 717 8.0E-20 T 09-03-2017 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Gene3D G3DSA:3.30.1490.70 520 548 8.0E-20 T 09-03-2017 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Pfam PF13298 DNA polymerase Ligase (LigD) 382 461 2.5E-29 T 09-03-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 525 836 5.2E-82 T 09-03-2017 IPR014146 DNA ligase D, ligase domain ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 SUPERFAMILY SSF56091 523 717 5.76E-43 T 09-03-2017 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 17 268 1.2E-76 T 09-03-2017 IPR014145 DNA ligase D, polymerase domain ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 SUPERFAMILY SSF50249 720 836 6.85E-33 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Pfam PF01068 ATP dependent DNA ligase domain 525 717 5.5E-34 T 09-03-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 544 552 - T 09-03-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Pfam PF04679 ATP dependent DNA ligase C terminal region 736 830 8.5E-27 T 09-03-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 ARZXY2_RS17285 62c7fa271fc086feb72628dd8bfaf8f1 839 Gene3D G3DSA:2.40.50.140 720 836 3.2E-43 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 SMART SM00382 98 247 2.1E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 SUPERFAMILY SSF52540 47 229 2.75E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 Pfam PF07724 AAA domain (Cdc48 subfamily) 97 252 1.2E-49 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 132 150 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 147 165 3.9E-43 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 176 194 3.9E-43 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 102 120 3.9E-43 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 209 223 3.9E-43 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS21720 edf946f95cd055048ab947f4bd32351d 252 Gene3D G3DSA:3.40.50.300 54 223 4.7E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 Gene3D G3DSA:3.40.800.10 12 314 8.5E-85 T 09-03-2017 IPR023696 Ureohydrolase domain ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 Pfam PF00491 Arginase family 48 313 2.6E-51 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 TIGRFAM TIGR01227 hutG: formimidoylglutamase 18 314 1.1E-82 T 09-03-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 Hamap MF_00737 Formimidoylglutamase [hutG]. 10 315 38.476 T 09-03-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 SUPERFAMILY SSF52768 22 314 1.98E-67 T 09-03-2017 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 ProSitePatterns PS01053 Arginase family signature. 244 265 - T 09-03-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 PRINTS PR00116 Arginase signature 127 142 2.0E-6 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 PRINTS PR00116 Arginase signature 276 290 2.0E-6 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS16760 7d4f6a87bdf183e5c8e14bd895ec217b 315 PRINTS PR00116 Arginase signature 241 270 2.0E-6 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 ARZXY2_RS15720 69cb7e3574d95d8d3a0caff0d8b7d584 312 SUPERFAMILY SSF161098 75 300 2.62E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15720 69cb7e3574d95d8d3a0caff0d8b7d584 312 Gene3D G3DSA:1.10.3720.10 82 310 7.3E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15720 69cb7e3574d95d8d3a0caff0d8b7d584 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 310 5.6E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19770 66fa10ee706f045b6e27ea5ee111079d 622 Pfam PF00723 Glycosyl hydrolases family 15 219 532 2.7E-55 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 ARZXY2_RS19770 66fa10ee706f045b6e27ea5ee111079d 622 SUPERFAMILY SSF48208 193 590 7.94E-102 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS19770 66fa10ee706f045b6e27ea5ee111079d 622 Gene3D G3DSA:1.50.10.10 216 604 2.2E-80 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS05850 15087de51be8ed71110b542464ce2566 66 Pfam PF12728 Helix-turn-helix domain 5 54 2.9E-12 T 09-03-2017 ARZXY2_RS05850 15087de51be8ed71110b542464ce2566 66 SUPERFAMILY SSF46955 5 52 4.58E-6 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS05850 15087de51be8ed71110b542464ce2566 66 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 52 5.7E-16 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS05850 15087de51be8ed71110b542464ce2566 66 Gene3D G3DSA:1.10.10.10 6 54 1.3E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 Gene3D G3DSA:3.40.1190.20 43 341 1.4E-52 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 SUPERFAMILY SSF53613 43 336 4.21E-52 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 280 293 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 Pfam PF00294 pfkB family carbohydrate kinase 71 325 9.7E-31 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 PRINTS PR00990 Ribokinase signature 73 92 1.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 PRINTS PR00990 Ribokinase signature 249 260 1.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS03815 7db02a48dce7c96ea0ddffd8b224253e 383 PRINTS PR00990 Ribokinase signature 211 226 1.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 111 241 8.9E-13 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 Gene3D G3DSA:1.10.357.10 35 242 5.0E-49 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00400 Tetracycline repressor protein signature 224 238 2.8E-10 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00400 Tetracycline repressor protein signature 61 84 2.8E-10 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00400 Tetracycline repressor protein signature 170 189 2.8E-10 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00400 Tetracycline repressor protein signature 113 132 2.8E-10 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 SUPERFAMILY SSF48498 111 242 5.89E-27 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 93 4.8E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 2.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 2.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS18370 34d164848ff8b259be6516fec8d8eb67 243 SUPERFAMILY SSF46689 49 101 3.64E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS13330 aebf7618f7492f9c53496f8543a482a1 286 Pfam PF00795 Carbon-nitrogen hydrolase 3 257 1.5E-35 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS13330 aebf7618f7492f9c53496f8543a482a1 286 SUPERFAMILY SSF56317 2 272 8.76E-58 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS13330 aebf7618f7492f9c53496f8543a482a1 286 Gene3D G3DSA:3.60.110.10 3 272 8.4E-60 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS09025 e009a6107a9df95d4db09fe990fbb372 320 Pfam PF01040 UbiA prenyltransferase family 43 283 9.9E-65 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 ARZXY2_RS09025 e009a6107a9df95d4db09fe990fbb372 320 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 28 310 3.7E-96 T 09-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 ARZXY2_RS09025 e009a6107a9df95d4db09fe990fbb372 320 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 312 19.148 T 09-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 ARZXY2_RS09025 e009a6107a9df95d4db09fe990fbb372 320 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 09-03-2017 IPR030470 UbiA prenyltransferase conserved site ARZXY2_RS14580 8ca81211c6b80e8b851bac70de4a8575 460 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 105 2.7E-15 T 09-03-2017 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 ARZXY2_RS14580 8ca81211c6b80e8b851bac70de4a8575 460 Pfam PF07196 Flagellin hook IN motif 125 177 2.7E-5 T 09-03-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 ARZXY2_RS14580 8ca81211c6b80e8b851bac70de4a8575 460 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 215 437 1.5E-24 T 09-03-2017 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 ARZXY2_RS14795 9974747a280826b6b3faf21a5993be68 445 SUPERFAMILY SSF103473 2 180 1.7E-28 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS14795 9974747a280826b6b3faf21a5993be68 445 SUPERFAMILY SSF103473 223 418 1.7E-28 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS14795 9974747a280826b6b3faf21a5993be68 445 Gene3D G3DSA:1.20.1250.20 23 169 3.0E-6 T 09-03-2017 ARZXY2_RS14795 9974747a280826b6b3faf21a5993be68 445 Gene3D G3DSA:1.20.1250.20 238 418 1.1E-12 T 09-03-2017 ARZXY2_RS14795 9974747a280826b6b3faf21a5993be68 445 Pfam PF07690 Major Facilitator Superfamily 18 351 3.3E-9 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS15575 6b62cc5a9f94b7913304cbd53b81bc6e 311 Pfam PF01292 Prokaryotic cytochrome b561 69 263 1.8E-12 T 09-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 ARZXY2_RS15575 6b62cc5a9f94b7913304cbd53b81bc6e 311 Gene3D G3DSA:1.20.950.20 71 253 2.3E-13 T 09-03-2017 ARZXY2_RS15575 6b62cc5a9f94b7913304cbd53b81bc6e 311 SUPERFAMILY SSF81342 67 265 3.3E-18 T 09-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 ARZXY2_RS02435 61b2d7e95dc54b56b4c3a4a5861da2da 205 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 47 3.3E-6 T 09-03-2017 IPR023833 Signal peptide, camelysin ARZXY2_RS19135 1842021b7e83f052484a3d53926f4c04 291 SUPERFAMILY SSF54593 6 269 1.32E-33 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS19135 1842021b7e83f052484a3d53926f4c04 291 Gene3D G3DSA:3.10.180.10 6 121 8.0E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS19135 1842021b7e83f052484a3d53926f4c04 291 Gene3D G3DSA:3.10.180.10 134 273 2.4E-34 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS19135 1842021b7e83f052484a3d53926f4c04 291 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 136 244 1.3E-9 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS19135 1842021b7e83f052484a3d53926f4c04 291 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 92 5.8E-6 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 ProSitePatterns PS01277 Ribonuclease PH signature. 126 139 - T 09-03-2017 IPR018336 Ribonuclease PH, conserved site ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 Hamap MF_00564 Ribonuclease PH [rph]. 11 249 47.342 T 09-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 Pfam PF03725 3' exoribonuclease family, domain 2 171 234 5.8E-10 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 12 248 1.0E-111 T 09-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 Gene3D G3DSA:3.30.230.70 11 249 8.2E-28 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 SUPERFAMILY SSF55666 166 249 1.96E-23 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 Pfam PF01138 3' exoribonuclease family, domain 1 20 150 3.0E-23 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 ARZXY2_RS05385 f1ea2e168740a06b3f0fbc43375aeb20 252 SUPERFAMILY SSF54211 11 192 9.11E-46 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS15165 df53752b74a7382fe214801aeb8307ef 228 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 9 227 34.083 T 09-03-2017 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 ARZXY2_RS15165 df53752b74a7382fe214801aeb8307ef 228 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 36 227 6.2E-53 T 09-03-2017 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 ARZXY2_RS15165 df53752b74a7382fe214801aeb8307ef 228 SUPERFAMILY SSF51366 11 223 8.95E-49 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 ARZXY2_RS15165 df53752b74a7382fe214801aeb8307ef 228 Gene3D G3DSA:3.20.20.70 6 227 2.6E-79 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 PIRSF PIRSF015626 1 281 1.7E-82 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 SUPERFAMILY SSF53927 23 278 1.96E-75 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 Pfam PF02634 FdhD/NarQ family 32 278 1.0E-78 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 Gene3D G3DSA:3.10.20.10 34 123 5.7E-25 T 09-03-2017 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 Gene3D G3DSA:3.40.140.10 140 278 4.1E-52 T 09-03-2017 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 279 34.038 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS16485 ca52fd55b0b99f76595575c44938ab8b 293 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 27 278 5.8E-49 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Gene3D G3DSA:3.40.50.1380 9 192 1.4E-77 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Gene3D G3DSA:3.40.140.20 379 546 6.2E-54 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 12 556 1.7E-170 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 SMART SM00851 23 137 1.5E-48 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 SUPERFAMILY SSF53927 222 556 1.2E-115 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 11 556 42.135 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Pfam PF01808 AICARFT/IMPCHase bienzyme 142 465 3.1E-111 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 PIRSF PIRSF000414 5 556 6.3E-197 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Pfam PF02142 MGS-like domain 23 136 4.9E-24 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 SUPERFAMILY SSF52335 11 200 1.74E-64 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 Gene3D G3DSA:3.40.140.20 252 371 8.8E-46 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS13395 2c879cca62f1705966a5f43c941ce1aa 556 SMART SM00798 142 466 6.7E-177 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS02905 7b2d2f6b4fe73e880842eda331ad7b31 348 SUPERFAMILY SSF51679 10 335 2.49E-56 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS02905 7b2d2f6b4fe73e880842eda331ad7b31 348 Gene3D G3DSA:3.20.20.30 7 343 1.1E-61 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS02905 7b2d2f6b4fe73e880842eda331ad7b31 348 Pfam PF00296 Luciferase-like monooxygenase 11 252 3.3E-30 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS07655 6df91cbef9a4a33ec278a375f4ed4f9e 215 Pfam PF07884 Vitamin K epoxide reductase family 30 162 4.2E-30 T 09-03-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 ARZXY2_RS07655 6df91cbef9a4a33ec278a375f4ed4f9e 215 SMART SM00756 25 166 3.3E-49 T 09-03-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 SUPERFAMILY SSF88946 3 80 2.2E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 Gene3D G3DSA:1.10.601.10 3 71 5.5E-6 T 09-03-2017 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 SUPERFAMILY SSF88659 83 143 1.13E-6 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 Pfam PF04542 Sigma-70 region 2 9 80 2.7E-8 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 SUPERFAMILY SSF88659 145 221 1.31E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 PIRSF PIRSF000770 1 240 8.8E-32 T 09-03-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 217 2.2E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 Gene3D G3DSA:1.10.10.10 83 127 1.3E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 Gene3D G3DSA:1.10.10.10 157 219 1.4E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14415 4b95407481f1c3476d7b009025cc05fb 271 Pfam PF04545 Sigma-70, region 4 169 216 1.5E-6 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 SMART SM00079 32 250 0.001 T 09-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 Gene3D G3DSA:3.40.190.10 210 250 8.3E-37 T 09-03-2017 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 Gene3D G3DSA:3.40.190.10 30 110 8.3E-37 T 09-03-2017 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 55 68 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 249 3.4E-56 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 SMART SM00062 32 251 1.5E-50 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 SUPERFAMILY SSF53850 22 251 4.91E-59 T 09-03-2017 ARZXY2_RS16075 a531077c6fa359a228c19118c68f7475 274 Gene3D G3DSA:3.40.190.10 111 198 2.4E-19 T 09-03-2017 ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 170 246 5.9E-10 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 Gene3D G3DSA:3.40.50.720 1 144 1.1E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 Gene3D G3DSA:3.30.360.10 145 339 2.1E-57 T 09-03-2017 ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 SUPERFAMILY SSF55347 135 304 1.16E-30 T 09-03-2017 ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 128 8.9E-19 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS14030 72078033841b22123789135776ba7ee5 340 SUPERFAMILY SSF51735 4 157 8.91E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18755 28c0cdd84194eee99a4fcd24f475091f 326 Pfam PF00892 EamA-like transporter family 157 293 2.0E-11 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18755 28c0cdd84194eee99a4fcd24f475091f 326 Pfam PF00892 EamA-like transporter family 8 143 1.3E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18755 28c0cdd84194eee99a4fcd24f475091f 326 SUPERFAMILY SSF103481 198 300 3.66E-5 T 09-03-2017 ARZXY2_RS18755 28c0cdd84194eee99a4fcd24f475091f 326 SUPERFAMILY SSF103481 43 145 3.4E-9 T 09-03-2017 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 Gene3D G3DSA:1.10.10.10 12 145 4.1E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 SMART SM00347 32 131 2.0E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.3E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.3E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.3E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 Pfam PF12802 MarR family 39 98 1.5E-11 T 09-03-2017 ARZXY2_RS11010 8cc1d2dc93eedc7d795d30ebd15c2fe2 148 SUPERFAMILY SSF46785 12 145 6.92E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 SMART SM00530 15 70 7.5E-17 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 Pfam PF07883 Cupin domain 111 177 1.6E-12 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 Pfam PF13560 Helix-turn-helix domain 12 70 9.1E-15 T 09-03-2017 ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 Gene3D G3DSA:1.10.260.40 11 81 7.3E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 SUPERFAMILY SSF51182 69 176 7.76E-19 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 SUPERFAMILY SSF47413 12 77 1.21E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS14635 eaf29898754eb4327689edf2bd3c807e 193 Gene3D G3DSA:2.60.120.10 90 180 1.5E-13 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 PIRSF PIRSF001365 2 305 2.8E-75 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 166 - T 09-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 SMART SM01130 4 303 9.3E-82 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 SUPERFAMILY SSF51569 3 304 3.56E-76 T 09-03-2017 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 Pfam PF00701 Dihydrodipicolinate synthetase family 5 300 3.9E-48 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 Gene3D G3DSA:3.20.20.70 3 304 5.3E-84 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 3.0E-9 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 3.0E-9 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS15155 80cf36eb5f77cdbae10afab09d92e57d 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 3.0E-9 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS01810 4ac6956db7ea1dcf545974edf86cce9a 66 SUPERFAMILY SSF160113 3 59 2.35E-15 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS01810 4ac6956db7ea1dcf545974edf86cce9a 66 Gene3D G3DSA:3.30.160.160 4 49 9.9E-12 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS01810 4ac6956db7ea1dcf545974edf86cce9a 66 Pfam PF07411 Domain of unknown function (DUF1508) 10 57 1.0E-12 T 09-03-2017 IPR010879 Domain of unknown function DUF1508 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 314 342 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 120 131 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Gene3D G3DSA:3.30.470.20 239 374 4.3E-47 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Gene3D G3DSA:3.40.50.20 13 142 5.6E-36 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 15 371 4.5E-103 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 14 372 39.721 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 PIRSF PIRSF039102 12 378 1.6E-106 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Pfam PF07478 D-ala D-ala ligase C-terminus 161 368 3.3E-66 T 09-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Gene3D G3DSA:3.30.1490.20 176 237 4.8E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 SUPERFAMILY SSF56059 153 374 5.3E-54 T 09-03-2017 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 Pfam PF01820 D-ala D-ala ligase N-terminus 15 143 6.0E-33 T 09-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05775 56dc7833354102351bcec655fcb208a5 379 SUPERFAMILY SSF52440 13 152 3.84E-35 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS09920 daa6a9a003bd8934639261bd5b038948 128 Gene3D G3DSA:3.10.180.10 4 103 1.5E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09920 daa6a9a003bd8934639261bd5b038948 128 SUPERFAMILY SSF54593 3 103 6.44E-11 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS00515 9802b52c0766c1f994ba7fb4b9e0d5c7 346 Gene3D G3DSA:3.90.245.10 10 318 4.8E-115 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ARZXY2_RS00515 9802b52c0766c1f994ba7fb4b9e0d5c7 346 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 16 26 - T 09-03-2017 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 ARZXY2_RS00515 9802b52c0766c1f994ba7fb4b9e0d5c7 346 SUPERFAMILY SSF53590 10 319 1.96E-106 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ARZXY2_RS00515 9802b52c0766c1f994ba7fb4b9e0d5c7 346 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 11 309 5.2E-78 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain ARZXY2_RS15500 15e31111362d769a50b5267d3a107226 206 Pfam PF03737 Demethylmenaquinone methyltransferase 40 167 7.5E-31 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS15500 15e31111362d769a50b5267d3a107226 206 Gene3D G3DSA:3.50.30.40 25 176 2.1E-39 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS15500 15e31111362d769a50b5267d3a107226 206 SUPERFAMILY SSF89562 16 176 1.57E-36 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS16420 be9ff1d0bfa038fe405bc5aa519f1a93 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 277 4.0E-31 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 345 54.0 T 09-03-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 Pfam PF00107 Zinc-binding dehydrogenase 175 302 1.3E-24 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 Gene3D G3DSA:3.40.50.720 174 288 3.0E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 SMART SM00829 8 343 0.006 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 Gene3D G3DSA:3.90.180.10 1 173 1.1E-46 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 SUPERFAMILY SSF50129 1 174 6.85E-50 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 4.5E-31 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS12300 a27322975aabaf0e3c8e33f942c69548 348 SUPERFAMILY SSF51735 143 302 8.02E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 Pfam PF07731 Multicopper oxidase 587 685 1.0E-20 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 Gene3D G3DSA:2.60.40.420 255 384 3.4E-29 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 ProSitePatterns PS00080 Multicopper oxidases signature 2. 669 680 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 SUPERFAMILY SSF49503 557 684 8.5E-32 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 SUPERFAMILY SSF49503 372 479 3.87E-8 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 Pfam PF07732 Multicopper oxidase 272 384 3.8E-29 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 SUPERFAMILY SSF49503 251 384 2.75E-32 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 Gene3D G3DSA:2.60.40.420 410 477 1.1E-6 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS14280 e6199cd8fa66341484022b3d934f8e7f 704 Gene3D G3DSA:2.60.40.420 560 684 5.9E-33 T 09-03-2017 IPR008972 Cupredoxin ARZXY2_RS04470 daff0c85742d5790ede308c13d8a81a2 233 Gene3D G3DSA:3.30.70.1100 135 232 2.6E-39 T 09-03-2017 ARZXY2_RS04470 daff0c85742d5790ede308c13d8a81a2 233 Pfam PF06778 Chlorite dismutase 37 223 5.1E-65 T 09-03-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase ARZXY2_RS04470 daff0c85742d5790ede308c13d8a81a2 233 SUPERFAMILY SSF54909 10 232 1.47E-72 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS04470 daff0c85742d5790ede308c13d8a81a2 233 Gene3D G3DSA:3.30.70.1030 12 134 4.2E-16 T 09-03-2017 ARZXY2_RS17830 4d390d642fa7777a978a9154b8182d1f 485 Gene3D G3DSA:3.30.43.10 44 98 7.7E-8 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS17830 4d390d642fa7777a978a9154b8182d1f 485 Gene3D G3DSA:3.30.465.10 100 210 8.8E-15 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS17830 4d390d642fa7777a978a9154b8182d1f 485 SUPERFAMILY SSF56176 22 210 2.76E-44 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS17830 4d390d642fa7777a978a9154b8182d1f 485 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 47 80 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 ARZXY2_RS17830 4d390d642fa7777a978a9154b8182d1f 485 Pfam PF01565 FAD binding domain 48 180 9.3E-26 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 SUPERFAMILY SSF52540 2 165 2.71E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 Gene3D G3DSA:3.40.50.300 4 163 1.4E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 Pfam PF01202 Shikimate kinase 15 162 7.3E-12 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 207 525 5.0E-58 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 8 161 6.5E-60 T 09-03-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 Gene3D G3DSA:3.20.20.300 218 537 2.1E-70 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 Gene3D G3DSA:3.40.50.1700 553 676 2.4E-4 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 ARZXY2_RS16200 303ca42bb1ad2b50419b87494f504425 757 SUPERFAMILY SSF51445 187 566 1.03E-78 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 Gene3D G3DSA:1.10.3720.10 326 590 2.5E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 SUPERFAMILY SSF161098 322 590 3.92E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 SUPERFAMILY SSF161098 25 310 4.97E-45 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 Gene3D G3DSA:1.10.3720.10 21 297 6.3E-41 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 402 584 7.5E-8 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17105 78caf835408949dd4706c779e8ddfc8e 608 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 295 3.2E-10 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS08395 dc02accab3370fdcd1192c4c362aea04 94 Gene3D G3DSA:3.30.1340.10 7 89 4.9E-18 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS08395 dc02accab3370fdcd1192c4c362aea04 94 SUPERFAMILY SSF55594 5 70 6.67E-14 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS08395 dc02accab3370fdcd1192c4c362aea04 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site ARZXY2_RS08395 dc02accab3370fdcd1192c4c362aea04 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 70 3.9E-14 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS08395 dc02accab3370fdcd1192c4c362aea04 94 Pfam PF00381 PTS HPr component phosphorylation site 7 92 1.1E-17 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 SUPERFAMILY SSF52374 4 298 4.15E-91 T 09-03-2017 ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 Gene3D G3DSA:3.40.50.620 3 190 3.0E-69 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 Pfam PF02569 Pantoate-beta-alanine ligase 5 296 1.0E-89 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 Gene3D G3DSA:3.30.1300.10 191 299 3.1E-30 T 09-03-2017 ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 Hamap MF_00158 Pantothenate synthetase [panC]. 4 298 38.158 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 ARZXY2_RS17950 ea9d97a62f2c609ff476aea22743c080 300 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 4 298 5.6E-80 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 ARZXY2_RS17125 0a016cf47270adc9f36fa7e9ad4e80c3 369 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 94 108 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS17125 0a016cf47270adc9f36fa7e9ad4e80c3 369 Pfam PF00348 Polyprenyl synthetase 48 303 9.4E-51 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 ARZXY2_RS17125 0a016cf47270adc9f36fa7e9ad4e80c3 369 SUPERFAMILY SSF48576 26 367 5.04E-62 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS17125 0a016cf47270adc9f36fa7e9ad4e80c3 369 Gene3D G3DSA:1.10.600.10 27 368 3.1E-69 T 09-03-2017 IPR008949 Isoprenoid synthase domain ARZXY2_RS02655 97b3e8f500a4848188f08cd25aae2194 183 Pfam PF02698 DUF218 domain 39 142 4.8E-10 T 09-03-2017 IPR003848 Domain of unknown function DUF218 ARZXY2_RS20355 606bd11153939d546c3f6fd4ac8e8866 126 TIGRFAM TIGR01374 soxD: sarcosine oxidase, delta subunit family 3 85 3.7E-38 T 09-03-2017 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 ARZXY2_RS20355 606bd11153939d546c3f6fd4ac8e8866 126 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 83 4.0E-36 T 09-03-2017 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 Pfam PF07690 Major Facilitator Superfamily 28 250 5.1E-29 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 SUPERFAMILY SSF103473 17 401 1.83E-70 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 PRINTS PR01035 Tetracycline resistance protein signature 176 196 2.3E-11 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 PRINTS PR01035 Tetracycline resistance protein signature 313 333 2.3E-11 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 PRINTS PR01035 Tetracycline resistance protein signature 33 49 2.3E-11 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 PRINTS PR01035 Tetracycline resistance protein signature 148 170 2.3E-11 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 Gene3D G3DSA:1.20.1250.20 23 201 4.8E-35 T 09-03-2017 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 278 294 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS06955 37bb69c748e02265589234951caff407 406 Gene3D G3DSA:1.20.1250.20 227 402 6.6E-29 T 09-03-2017 ARZXY2_RS04360 5e0a8dc29cd8a24de8bc0e055eb4e056 242 Pfam PF06210 Protein of unknown function (DUF1003) 56 160 3.6E-36 T 09-03-2017 IPR010406 Protein of unknown function DUF1003 ARZXY2_RS05445 b7420d75a2221df78dc1c40f7b8aa797 390 Gene3D G3DSA:3.60.21.10 1 268 1.2E-64 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS05445 b7420d75a2221df78dc1c40f7b8aa797 390 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 250 7.8E-53 T 09-03-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 ARZXY2_RS05445 b7420d75a2221df78dc1c40f7b8aa797 390 SUPERFAMILY SSF56300 1 312 3.04E-51 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS05445 b7420d75a2221df78dc1c40f7b8aa797 390 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 274 346 2.3E-5 T 09-03-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain ARZXY2_RS05445 b7420d75a2221df78dc1c40f7b8aa797 390 Pfam PF00149 Calcineurin-like phosphoesterase 1 91 3.0E-11 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 ARZXY2_RS02095 e375b16f2811582b67e8c6b44d00d2ff 335 SUPERFAMILY SSF53474 4 331 9.34E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02095 e375b16f2811582b67e8c6b44d00d2ff 335 Gene3D G3DSA:3.40.50.1820 1 333 7.1E-83 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02095 e375b16f2811582b67e8c6b44d00d2ff 335 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 331 1.9E-99 T 09-03-2017 IPR008391 Acetyl xylan esterase ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 Gene3D G3DSA:1.10.150.130 12 106 6.4E-23 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 Gene3D G3DSA:1.10.443.10 119 301 3.3E-54 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 15 96 1.3E-17 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 SUPERFAMILY SSF56349 120 306 1.18E-52 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 308 55.351 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 Pfam PF00589 Phage integrase family 120 293 8.3E-43 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS07310 c7e0c992f61d057d59c34a9a865f30f2 308 SUPERFAMILY SSF47823 14 107 2.75E-13 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal ARZXY2_RS08630 4e27f5e1066e3790d761f9297814961b 131 SUPERFAMILY SSF54534 22 130 1.89E-38 T 09-03-2017 ARZXY2_RS08630 4e27f5e1066e3790d761f9297814961b 131 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 38 128 5.1E-30 T 09-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 ARZXY2_RS08630 4e27f5e1066e3790d761f9297814961b 131 Gene3D G3DSA:3.10.50.40 19 130 1.5E-40 T 09-03-2017 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 905 919 1.4E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 919 935 1.4E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 935 947 1.4E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 SUPERFAMILY SSF48452 611 690 1.63E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 SUPERFAMILY SSF48452 396 421 1.63E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 SUPERFAMILY SSF46894 896 960 3.13E-17 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 SUPERFAMILY SSF52540 11 236 1.68E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Gene3D G3DSA:3.40.50.300 11 164 1.6E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Pfam PF13191 AAA ATPase domain 11 157 3.1E-20 T 09-03-2017 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Gene3D G3DSA:1.25.40.10 622 691 1.2E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Gene3D G3DSA:1.25.40.10 369 416 1.2E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 ProSitePatterns PS00622 LuxR-type HTH domain signature. 919 946 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Pfam PF00196 Bacterial regulatory proteins, luxR family 905 959 4.7E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 SMART SM00421 902 959 2.5E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS09520 267ca2f2be947e31a6f20074ebdf4f73 966 Gene3D G3DSA:1.10.10.10 893 960 7.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11125 452b2cb526820990e40a9cae715c0fb8 340 Gene3D G3DSA:3.40.50.10330 3 147 1.7E-29 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS11125 452b2cb526820990e40a9cae715c0fb8 340 Pfam PF01513 ATP-NAD kinase 65 275 1.0E-59 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS11125 452b2cb526820990e40a9cae715c0fb8 340 SUPERFAMILY SSF111331 4 297 5.1E-78 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS11125 452b2cb526820990e40a9cae715c0fb8 340 Gene3D G3DSA:2.60.200.30 148 267 6.1E-39 T 09-03-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS11125 452b2cb526820990e40a9cae715c0fb8 340 Hamap MF_00361 NAD kinase [nadK]. 3 291 29.456 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 4.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 Pfam PF00106 short chain dehydrogenase 4 185 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 SUPERFAMILY SSF51735 1 228 1.38E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 Gene3D G3DSA:3.40.50.720 2 228 4.2E-69 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 4.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 4.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 4.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS06515 1d9a433f2722cd2ec54483abe3e3dd57 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 174 2.6E-5 T 09-03-2017 ARZXY2_RS13085 8c4b8444c8add5ca274034bd3888f7b2 453 SUPERFAMILY SSF53822 82 446 7.07E-66 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS13085 8c4b8444c8add5ca274034bd3888f7b2 453 Pfam PF13458 Periplasmic binding protein 82 388 4.4E-42 T 09-03-2017 IPR028081 Leucine-binding protein domain ARZXY2_RS13085 8c4b8444c8add5ca274034bd3888f7b2 453 Gene3D G3DSA:3.40.50.2300 82 280 3.1E-52 T 09-03-2017 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 SUPERFAMILY SSF53623 229 294 3.27E-30 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 SUPERFAMILY SSF53623 49 196 3.27E-30 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 Gene3D G3DSA:3.40.1190.10 49 198 2.5E-39 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 Gene3D G3DSA:3.40.1190.10 232 296 2.5E-39 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 Pfam PF08245 Mur ligase middle domain 52 274 3.6E-16 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 ARZXY2_RS07955 49a8698c368d36c69c4c6c0844126a0c 439 Pfam PF08353 Domain of unknown function (DUF1727) 317 422 4.9E-26 T 09-03-2017 IPR013564 Domain of unknown function DUF1727 ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 PRINTS PR00625 DnaJ domain signature 27 42 7.2E-12 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 PRINTS PR00625 DnaJ domain signature 71 90 7.2E-12 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 PRINTS PR00625 DnaJ domain signature 51 71 7.2E-12 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 PRINTS PR00625 DnaJ domain signature 9 27 7.2E-12 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 Gene3D G3DSA:1.10.287.110 4 80 2.2E-20 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 SUPERFAMILY SSF46565 4 79 1.24E-19 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 Pfam PF00226 DnaJ domain 7 76 6.4E-17 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS13440 325a9d83a9d283e039de0e06769c8004 146 SMART SM00271 6 71 5.8E-13 T 09-03-2017 IPR001623 DnaJ domain ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 Pfam PF01614 Bacterial transcriptional regulator 126 244 2.9E-21 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 Pfam PF09339 IclR helix-turn-helix domain 12 55 3.0E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 SUPERFAMILY SSF55781 71 246 1.96E-40 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 SMART SM00346 6 94 4.2E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 SUPERFAMILY SSF46785 7 77 1.91E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 Gene3D G3DSA:3.30.450.40 83 246 1.1E-42 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS00885 4fd588e68cd73a2203bbfc18c2712597 246 Gene3D G3DSA:1.10.10.10 5 76 1.4E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15970 f7a81b504594642541887de008fdfd54 141 Gene3D G3DSA:3.40.50.720 12 137 2.2E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15970 f7a81b504594642541887de008fdfd54 141 SMART SM00881 14 110 2.3E-13 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS15970 f7a81b504594642541887de008fdfd54 141 Pfam PF13380 CoA binding domain 19 135 3.8E-32 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS15970 f7a81b504594642541887de008fdfd54 141 SUPERFAMILY SSF51735 4 140 1.84E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 PIRSF PIRSF005639 13 233 2.0E-69 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 Pfam PF01174 SNO glutamine amidotransferase family 20 229 5.6E-54 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 ProSitePatterns PS01236 PdxT/SNO family family signature. 55 65 - T 09-03-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 17 226 2.9E-62 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 18 228 37.71 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 SUPERFAMILY SSF52317 17 229 4.73E-46 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07960 38887ff3aa05df20418ab562681c14fa 233 Gene3D G3DSA:3.40.50.880 16 231 4.8E-75 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS16115 0587922bd9ae83d840d28602717eb722 151 Gene3D G3DSA:1.10.10.10 19 141 3.6E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16115 0587922bd9ae83d840d28602717eb722 151 Pfam PF01047 MarR family 43 100 3.1E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS16115 0587922bd9ae83d840d28602717eb722 151 SUPERFAMILY SSF46785 18 143 7.28E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16115 0587922bd9ae83d840d28602717eb722 151 SMART SM00347 36 135 1.7E-21 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11235 bee7d12b3ba67bc7d26f95934282bd15 362 PIRSF PIRSF015921 5 354 2.5E-72 T 09-03-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 ARZXY2_RS11235 bee7d12b3ba67bc7d26f95934282bd15 362 Pfam PF00487 Fatty acid desaturase 68 327 1.7E-41 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 ARZXY2_RS16400 4ed8d4a886932ea14bb77c8a7d2db57b 384 Gene3D G3DSA:3.20.20.140 7 382 7.8E-114 T 09-03-2017 ARZXY2_RS16400 4ed8d4a886932ea14bb77c8a7d2db57b 384 Pfam PF04909 Amidohydrolase 225 381 2.3E-9 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS16400 4ed8d4a886932ea14bb77c8a7d2db57b 384 SUPERFAMILY SSF51556 202 381 2.09E-10 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS17040 75b172a59e0c768612b115c65ab38581 277 Gene3D G3DSA:3.90.850.10 58 275 8.0E-73 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17040 75b172a59e0c768612b115c65ab38581 277 SUPERFAMILY SSF56529 61 274 5.63E-72 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17040 75b172a59e0c768612b115c65ab38581 277 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 272 4.7E-60 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS16160 70415bee4b55ec332ce6a6aa4d0de601 227 Pfam PF00588 SpoU rRNA Methylase family 79 215 3.0E-26 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ARZXY2_RS16160 70415bee4b55ec332ce6a6aa4d0de601 227 Gene3D G3DSA:3.40.1280.10 60 224 1.0E-42 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS16160 70415bee4b55ec332ce6a6aa4d0de601 227 SUPERFAMILY SSF75217 58 225 3.79E-40 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS09265 9ec792637288ef86d2776bedd7646d69 370 Gene3D G3DSA:3.40.710.10 186 334 2.9E-17 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS09265 9ec792637288ef86d2776bedd7646d69 370 Pfam PF00144 Beta-lactamase 92 175 8.6E-10 T 09-03-2017 IPR001466 Beta-lactamase-related ARZXY2_RS09265 9ec792637288ef86d2776bedd7646d69 370 Pfam PF00144 Beta-lactamase 184 333 2.3E-10 T 09-03-2017 IPR001466 Beta-lactamase-related ARZXY2_RS09265 9ec792637288ef86d2776bedd7646d69 370 SUPERFAMILY SSF56601 74 338 3.33E-33 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS09265 9ec792637288ef86d2776bedd7646d69 370 Gene3D G3DSA:3.40.710.10 57 175 1.3E-13 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS09105 617e7c18714aab82f94ff7cde7ced222 222 SUPERFAMILY SSF69593 10 216 5.1E-44 T 09-03-2017 ARZXY2_RS09105 617e7c18714aab82f94ff7cde7ced222 222 Pfam PF01553 Acyltransferase 21 151 1.3E-23 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS09105 617e7c18714aab82f94ff7cde7ced222 222 SMART SM00563 35 154 4.1E-31 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS09105 617e7c18714aab82f94ff7cde7ced222 222 Gene3D G3DSA:3.40.1130.10 19 206 1.1E-28 T 09-03-2017 ARZXY2_RS17380 1ace571b6d60c28873cd51ace4017697 196 SUPERFAMILY SSF55729 1 174 9.15E-40 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17380 1ace571b6d60c28873cd51ace4017697 196 Gene3D G3DSA:3.40.630.30 1 179 9.9E-54 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17380 1ace571b6d60c28873cd51ace4017697 196 SMART SM01006 6 53 9.7E-16 T 09-03-2017 IPR019432 Siderophore biosynthesis protein, conserved domain ARZXY2_RS17380 1ace571b6d60c28873cd51ace4017697 196 Pfam PF13523 Acetyltransferase (GNAT) domain 9 153 8.5E-46 T 09-03-2017 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 31 45 1.9E-6 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 45 63 1.9E-6 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 SMART SM00420 13 65 2.8E-14 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 Pfam PF08220 DeoR-like helix-turn-helix domain 13 66 4.2E-14 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 Gene3D G3DSA:3.40.50.1360 84 222 3.6E-9 T 09-03-2017 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 SUPERFAMILY SSF46785 10 66 9.1E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10060 52206462938175f152e47361015f9378 260 Pfam PF00455 DeoR C terminal sensor domain 83 238 9.8E-37 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain ARZXY2_RS10060 52206462938175f152e47361015f9378 260 SUPERFAMILY SSF100950 84 240 1.47E-22 T 09-03-2017 ARZXY2_RS10060 52206462938175f152e47361015f9378 260 Gene3D G3DSA:1.10.10.10 6 67 3.5E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10060 52206462938175f152e47361015f9378 260 SMART SM01134 80 240 1.7E-46 T 09-03-2017 ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 Gene3D G3DSA:1.10.10.10 123 218 5.8E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 9.7E-23 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 Pfam PF00072 Response regulator receiver domain 3 110 8.4E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 Gene3D G3DSA:3.40.50.2300 2 122 9.1E-33 T 09-03-2017 ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 SUPERFAMILY SSF52172 2 183 7.08E-33 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 SMART SM00862 145 217 4.0E-26 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS15555 9e6f8704e50c68cb585d5ed1a0429002 220 SMART SM00448 1 109 6.4E-31 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS01250 4e0be38f3e98e2ba06659e1e94edf918 153 Gene3D G3DSA:2.30.130.30 14 119 7.6E-8 T 09-03-2017 ARZXY2_RS01250 4e0be38f3e98e2ba06659e1e94edf918 153 SUPERFAMILY SSF88697 15 121 4.14E-14 T 09-03-2017 IPR015947 PUA-like domain ARZXY2_RS16560 a0d52716fcff162e8d214a1d9306241c 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 266 2.5E-58 T 09-03-2017 ARZXY2_RS16560 a0d52716fcff162e8d214a1d9306241c 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 1.5E-74 T 09-03-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 ARZXY2_RS16560 a0d52716fcff162e8d214a1d9306241c 268 Gene3D G3DSA:3.60.10.10 2 266 8.0E-77 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS16560 a0d52716fcff162e8d214a1d9306241c 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 259 1.5E-19 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS16560 a0d52716fcff162e8d214a1d9306241c 268 SUPERFAMILY SSF56219 2 266 4.58E-69 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS00465 c068fbb9047cde746f82e34053aa644e 517 Gene3D G3DSA:1.10.275.10 6 201 3.3E-46 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS00465 c068fbb9047cde746f82e34053aa644e 517 Pfam PF00221 Aromatic amino acid lyase 22 478 3.7E-112 T 09-03-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 ARZXY2_RS00465 c068fbb9047cde746f82e34053aa644e 517 Gene3D G3DSA:1.20.200.10 204 495 4.2E-68 T 09-03-2017 ARZXY2_RS00465 c068fbb9047cde746f82e34053aa644e 517 SUPERFAMILY SSF48557 5 499 5.89E-116 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS10700 59b5951536a60f2e81c91fc3ebfe20be 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 121 4.3E-10 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS10700 59b5951536a60f2e81c91fc3ebfe20be 300 Gene3D G3DSA:3.40.50.720 1 233 5.9E-16 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10700 59b5951536a60f2e81c91fc3ebfe20be 300 SUPERFAMILY SSF51735 1 292 5.24E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10700 59b5951536a60f2e81c91fc3ebfe20be 300 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 291 4.5E-80 T 09-03-2017 IPR010099 Epimerase family protein SDR39U1 ARZXY2_RS10700 59b5951536a60f2e81c91fc3ebfe20be 300 Pfam PF08338 Domain of unknown function (DUF1731) 247 294 4.4E-13 T 09-03-2017 IPR013549 Domain of unknown function DUF1731 ARZXY2_RS04335 599854d2eff99b073a82fe873f6e30b1 210 SUPERFAMILY SSF53335 20 210 3.34E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS04335 599854d2eff99b073a82fe873f6e30b1 210 Pfam PF01596 O-methyltransferase 29 209 2.7E-24 T 09-03-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 ARZXY2_RS04335 599854d2eff99b073a82fe873f6e30b1 210 Gene3D G3DSA:3.40.50.150 12 210 5.9E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10610 636f79cf7b43fe978a1214efc95c2aa1 346 SUPERFAMILY SSF55729 146 341 3.44E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10610 636f79cf7b43fe978a1214efc95c2aa1 346 SUPERFAMILY SSF55729 18 132 1.78E-10 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10610 636f79cf7b43fe978a1214efc95c2aa1 346 Pfam PF00583 Acetyltransferase (GNAT) family 254 333 3.7E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS10610 636f79cf7b43fe978a1214efc95c2aa1 346 Gene3D G3DSA:3.40.630.30 194 345 3.2E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS10610 636f79cf7b43fe978a1214efc95c2aa1 346 Gene3D G3DSA:3.40.630.30 30 175 4.7E-10 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Pfam PF07085 DRTGG domain 223 318 1.1E-15 T 09-03-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Gene3D G3DSA:3.40.50.300 4 208 2.3E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 383 684 6.6E-113 T 09-03-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 SUPERFAMILY SSF53659 367 687 4.93E-90 T 09-03-2017 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Pfam PF01515 Phosphate acetyl/butaryl transferase 368 684 5.2E-120 T 09-03-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 PIRSF PIRSF006107 1 689 9.0E-160 T 09-03-2017 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 SUPERFAMILY SSF52540 1 214 5.84E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 SUPERFAMILY SSF75138 208 325 2.08E-15 T 09-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Gene3D G3DSA:3.40.50.10750 502 660 2.4E-58 T 09-03-2017 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Pfam PF13500 AAA domain 4 203 1.6E-20 T 09-03-2017 ARZXY2_RS09820 1221387df3394c05b48dc3b8de9a67b1 689 Gene3D G3DSA:3.40.1390.20 209 341 2.1E-19 T 09-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 SUPERFAMILY SSF52317 3 194 7.15E-47 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 SUPERFAMILY SSF46689 265 315 3.05E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 Gene3D G3DSA:1.10.10.60 221 265 3.7E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 Gene3D G3DSA:3.40.50.880 4 220 1.6E-51 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 SMART SM00342 228 311 2.7E-25 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 Pfam PF12833 Helix-turn-helix domain 234 312 6.8E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 Pfam PF01965 DJ-1/PfpI family 3 172 4.0E-21 T 09-03-2017 IPR002818 DJ-1/PfpI ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 Gene3D G3DSA:1.10.10.60 266 314 8.6E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS05125 96e5a96bb088806befcd27cb48697489 322 SUPERFAMILY SSF46689 214 261 5.82E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS13185 8ca089ea3c2fa7aebd5b761385ce8c5f 143 Pfam PF02566 OsmC-like protein 39 136 5.3E-16 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS13185 8ca089ea3c2fa7aebd5b761385ce8c5f 143 SUPERFAMILY SSF82784 1 138 2.62E-39 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS13185 8ca089ea3c2fa7aebd5b761385ce8c5f 143 Gene3D G3DSA:3.30.300.20 45 139 1.4E-33 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS13185 8ca089ea3c2fa7aebd5b761385ce8c5f 143 Gene3D G3DSA:2.20.25.10 1 44 4.2E-18 T 09-03-2017 ARZXY2_RS13185 8ca089ea3c2fa7aebd5b761385ce8c5f 143 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 1.9E-51 T 09-03-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 09-03-2017 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 Pfam PF00406 Adenylate kinase 6 164 1.8E-51 T 09-03-2017 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 Gene3D G3DSA:3.40.50.300 3 185 3.5E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 SUPERFAMILY SSF52540 2 187 1.46E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 PRINTS PR00094 Adenylate kinase signature 82 98 5.8E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 PRINTS PR00094 Adenylate kinase signature 5 18 5.8E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 PRINTS PR00094 Adenylate kinase signature 33 47 5.8E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 PRINTS PR00094 Adenylate kinase signature 151 165 5.8E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 PRINTS PR00094 Adenylate kinase signature 134 149 5.8E-30 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS03595 280ab7b69d1e55a62b8a23ed27b8e501 192 Hamap MF_00235 Adenylate kinase [adk]. 2 187 42.789 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 Pfam PF01345 Domain of unknown function DUF11 701 732 2.4E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 Pfam PF01345 Domain of unknown function DUF11 557 614 4.0E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 702 731 6.1E-9 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 939 966 6.2E-4 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 585 613 2.2E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 820 849 8.7E-7 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS17400 9d358257076516f5e8cdc9673f903188 1204 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1056 1086 3.7E-5 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS19395 e185611368eec23f0ef1a841416a4b57 504 Pfam PF00665 Integrase core domain 113 235 9.0E-17 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS19395 e185611368eec23f0ef1a841416a4b57 504 SUPERFAMILY SSF53098 109 284 1.47E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS19395 e185611368eec23f0ef1a841416a4b57 504 Gene3D G3DSA:3.30.420.10 112 277 4.5E-12 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 PRINTS PR00990 Ribokinase signature 8 29 3.2E-32 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 PRINTS PR00990 Ribokinase signature 106 119 3.2E-32 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 PRINTS PR00990 Ribokinase signature 172 187 3.2E-32 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 PRINTS PR00990 Ribokinase signature 35 54 3.2E-32 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 PRINTS PR00990 Ribokinase signature 222 233 3.2E-32 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 Hamap MF_01987 Ribokinase [rbsK]. 4 310 24.681 T 09-03-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 Gene3D G3DSA:3.40.1190.20 6 309 2.6E-82 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 SUPERFAMILY SSF53613 3 309 3.27E-73 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 Pfam PF00294 pfkB family carbohydrate kinase 6 303 3.1E-59 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS00505 1cdfe05c831675afbacde7723a9a8ac9 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 SMART SM00478 45 197 5.5E-34 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 170 3.8E-12 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 SUPERFAMILY SSF48150 12 224 7.38E-63 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 Gene3D G3DSA:1.10.340.30 27 129 3.4E-35 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 199 215 4.4E-4 T 09-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 Pfam PF00633 Helix-hairpin-helix motif 106 134 4.8E-7 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 ProSitePatterns PS01155 Endonuclease III family signature. 108 137 - T 09-03-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 199 215 - T 09-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS17755 37f0af7314cb9b28460b2c888702aa6e 316 Gene3D G3DSA:1.10.1670.10 130 224 1.8E-32 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 SUPERFAMILY SSF52402 5 134 1.0E-15 T 09-03-2017 ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 SUPERFAMILY SSF52402 142 279 2.68E-28 T 09-03-2017 ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 PRINTS PR01438 Universal stress protein signature 239 251 2.2E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 PRINTS PR01438 Universal stress protein signature 140 158 2.2E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 PRINTS PR01438 Universal stress protein signature 257 279 2.2E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 Gene3D G3DSA:3.40.50.620 120 278 2.1E-35 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 Gene3D G3DSA:3.40.50.620 1 106 5.0E-16 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 Pfam PF00582 Universal stress protein family 142 279 4.0E-21 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09870 9930ed005457b9eb3fac0465fe9eecc1 287 Pfam PF00582 Universal stress protein family 1 132 5.0E-13 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 ProSitePatterns PS00216 Sugar transport proteins signature 1. 81 97 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 Gene3D G3DSA:1.20.1250.20 24 212 2.5E-29 T 09-03-2017 ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 Gene3D G3DSA:1.20.1250.20 240 419 5.3E-26 T 09-03-2017 ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 SUPERFAMILY SSF103473 25 418 1.31E-51 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 Pfam PF07690 Major Facilitator Superfamily 251 421 2.1E-19 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00150 8fc204e01ea16fa5363e44a3578afe5c 428 Pfam PF07690 Major Facilitator Superfamily 46 215 4.2E-23 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 SMART SM00732 13 119 1.7E-19 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 16 149 2.0E-25 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 Gene3D G3DSA:3.30.420.140 13 155 1.3E-42 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 Pfam PF03652 Holliday junction resolvase 15 151 9.0E-39 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 SUPERFAMILY SSF53098 13 153 7.74E-33 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS08065 2b671a3f761e9ad7c356c0c7a15aa1f6 196 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 13 154 20.586 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 Gene3D G3DSA:3.40.50.720 172 292 1.6E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 SUPERFAMILY SSF51735 142 312 1.62E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 SUPERFAMILY SSF50129 2 177 2.28E-48 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 Gene3D G3DSA:3.90.180.10 2 171 2.1E-49 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 127 1.0E-29 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 Pfam PF00107 Zinc-binding dehydrogenase 178 307 1.9E-20 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 ARZXY2_RS00795 0980bb4ee674651e7a671435d82a8428 349 SMART SM00829 10 344 1.5E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 SUPERFAMILY SSF51905 520 581 5.59E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 SUPERFAMILY SSF51905 26 336 5.59E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Pfam PF05199 GMC oxidoreductase 517 575 6.0E-16 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Pfam PF00890 FAD binding domain 31 63 4.7E-6 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Gene3D G3DSA:3.50.50.60 514 581 5.4E-72 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Gene3D G3DSA:3.50.50.60 28 156 5.4E-72 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Gene3D G3DSA:3.50.50.60 232 338 5.4E-72 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12630 9d7f9ff48844166b781639e62fc82373 888 Gene3D G3DSA:3.50.50.60 479 480 5.4E-72 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18200 23d6a5839da966492fa46543f30f2a8a 201 SUPERFAMILY SSF55469 19 198 5.23E-35 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ARZXY2_RS18200 23d6a5839da966492fa46543f30f2a8a 201 Pfam PF00881 Nitroreductase family 31 178 5.3E-10 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 ARZXY2_RS18200 23d6a5839da966492fa46543f30f2a8a 201 Gene3D G3DSA:3.40.109.10 6 199 1.0E-29 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 Gene3D G3DSA:3.50.50.60 3 187 2.1E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 Gene3D G3DSA:3.50.50.60 290 328 2.1E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 SUPERFAMILY SSF51905 279 369 1.11E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 SUPERFAMILY SSF51905 5 184 1.11E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 Pfam PF01494 FAD binding domain 5 346 3.0E-49 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 9.6E-21 T 09-03-2017 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.6E-21 T 09-03-2017 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 9.6E-21 T 09-03-2017 ARZXY2_RS18690 aa8d3a5a2c3593ec74747742b592d666 419 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 9.6E-21 T 09-03-2017 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 Pfam PF13394 4Fe-4S single cluster domain 43 127 5.4E-8 T 09-03-2017 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 SMART SM00729 36 241 1.0E-4 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 27 369 4.8E-107 T 09-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 Gene3D G3DSA:3.20.20.70 26 343 1.8E-77 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 SUPERFAMILY SSF102114 26 312 8.89E-70 T 09-03-2017 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 27 369 39.131 T 09-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 Pfam PF06463 Molybdenum Cofactor Synthesis C 208 346 1.5E-34 T 09-03-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 42 53 - T 09-03-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11485 90fdb1ab608562adf76f32ec6bd5a242 369 Pfam PF04055 Radical SAM superfamily 42 201 5.7E-33 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS07710 c1710a6e5ef7c3184ada30af85efbfc1 135 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 109 22.408 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS ARZXY2_RS07710 c1710a6e5ef7c3184ada30af85efbfc1 135 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 108 8.4E-31 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS ARZXY2_RS07710 c1710a6e5ef7c3184ada30af85efbfc1 135 Gene3D G3DSA:3.30.460.10 10 112 3.5E-32 T 09-03-2017 ARZXY2_RS07710 c1710a6e5ef7c3184ada30af85efbfc1 135 SUPERFAMILY SSF81301 10 117 2.29E-35 T 09-03-2017 ARZXY2_RS07710 c1710a6e5ef7c3184ada30af85efbfc1 135 Pfam PF02410 Ribosomal silencing factor during starvation 14 108 1.8E-22 T 09-03-2017 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 SUPERFAMILY SSF88659 121 171 2.99E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 SUPERFAMILY SSF88946 20 105 2.51E-9 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 Pfam PF04545 Sigma-70, region 4 122 171 9.2E-13 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 Pfam PF04542 Sigma-70 region 2 40 90 7.7E-5 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 Gene3D G3DSA:1.10.10.10 122 172 1.4E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 172 5.9E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS20140 67798f81f4975f56676c08df9319d6c4 185 Gene3D G3DSA:1.10.1740.10 21 112 1.9E-10 T 09-03-2017 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 97 688 1.0E-157 T 09-03-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 SUPERFAMILY SSF48168 10 168 3.27E-57 T 09-03-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Gene3D G3DSA:3.20.70.20 569 683 2.8E-53 T 09-03-2017 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Gene3D G3DSA:3.20.70.20 344 507 2.8E-53 T 09-03-2017 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Gene3D G3DSA:3.20.70.20 88 291 2.8E-53 T 09-03-2017 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 SUPERFAMILY SSF51998 169 690 5.49E-186 T 09-03-2017 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 5.3E-31 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 94 165 8.0E-11 T 09-03-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 685 1.9E-142 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 10 706 0.0 T 09-03-2017 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07800 ddb491f8b265ed43bdd68b395f873132 706 Pfam PF08343 Ribonucleotide reductase N-terminal 10 91 1.4E-31 T 09-03-2017 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 SUPERFAMILY SSF53597 28 197 1.14E-55 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 PRINTS PR00070 Dihydrofolate reductase signature 127 141 8.9E-17 T 09-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 PRINTS PR00070 Dihydrofolate reductase signature 66 77 8.9E-17 T 09-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 PRINTS PR00070 Dihydrofolate reductase signature 39 49 8.9E-17 T 09-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 PRINTS PR00070 Dihydrofolate reductase signature 53 61 8.9E-17 T 09-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 Gene3D G3DSA:3.40.430.10 24 197 3.6E-59 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 PIRSF PIRSF000194 22 199 1.1E-53 T 09-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 39 61 - T 09-03-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 ARZXY2_RS03280 4ec1d0607120ac7cd7fc52e2c1bc7943 199 Pfam PF00186 Dihydrofolate reductase 28 196 5.3E-53 T 09-03-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 Gene3D G3DSA:3.40.309.10 279 468 1.6E-70 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 SUPERFAMILY SSF53720 11 499 6.28E-170 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 Gene3D G3DSA:3.40.605.10 18 278 7.4E-96 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 Pfam PF00171 Aldehyde dehydrogenase family 28 493 2.0E-171 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 20 506 4.8E-203 T 09-03-2017 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 ARZXY2_RS09375 6ad916b96ef30531858eb6078f39ea0c 513 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 123 4.5E-8 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 143 216 2.8E-10 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 Gene3D G3DSA:1.10.760.10 47 133 2.9E-18 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 PIRSF PIRSF000007 1 261 6.5E-106 T 09-03-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 SUPERFAMILY SSF46626 10 128 8.75E-19 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 Gene3D G3DSA:1.10.760.10 142 221 5.5E-15 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS08415 070d9cdb28b41b1bc0618695a3fe7e3f 262 SUPERFAMILY SSF46626 129 218 3.2E-26 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 ARZXY2_RS17815 b7b027bcb0cef48c371d2b3eaf855b56 313 SUPERFAMILY SSF82549 9 312 2.62E-121 T 09-03-2017 ARZXY2_RS17815 b7b027bcb0cef48c371d2b3eaf855b56 313 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 2 309 4.8E-143 T 09-03-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 ARZXY2_RS17815 b7b027bcb0cef48c371d2b3eaf855b56 313 Gene3D G3DSA:3.40.50.10440 2 163 9.6E-68 T 09-03-2017 ARZXY2_RS17815 b7b027bcb0cef48c371d2b3eaf855b56 313 Pfam PF02733 Dak1 domain 2 307 5.8E-133 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS17815 b7b027bcb0cef48c371d2b3eaf855b56 313 Gene3D G3DSA:3.30.1180.20 165 312 8.2E-60 T 09-03-2017 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 SUPERFAMILY SSF117892 57 191 1.83E-40 T 09-03-2017 IPR001107 Band 7 domain ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 160 178 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 179 200 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 116 133 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 33 55 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 81 102 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 PRINTS PR00721 Stomatin signature 136 159 2.4E-32 T 09-03-2017 IPR001972 Stomatin family GO:0016020 ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 SMART SM00244 26 184 2.3E-57 T 09-03-2017 IPR001107 Band 7 domain ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 ProSitePatterns PS01270 Band 7 protein family signature. 140 168 - T 09-03-2017 IPR018080 Band 7/stomatin-like, conserved site ARZXY2_RS08585 d1536ee0654aa04ee9afefce4877b44c 323 Pfam PF01145 SPFH domain / Band 7 family 30 199 3.8E-36 T 09-03-2017 IPR001107 Band 7 domain ARZXY2_RS03160 82d6b70faadef4973a81dc20821ae748 157 Pfam PF01476 LysM domain 113 157 5.2E-8 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS03160 82d6b70faadef4973a81dc20821ae748 157 Gene3D G3DSA:3.10.350.10 113 157 2.5E-11 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS03160 82d6b70faadef4973a81dc20821ae748 157 SMART SM00257 111 157 9.1E-9 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS03160 82d6b70faadef4973a81dc20821ae748 157 SUPERFAMILY SSF54106 111 157 2.35E-8 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS12120 fe00a61208af2b6b2e671102c316417e 398 Pfam PF00534 Glycosyl transferases group 1 209 366 8.0E-35 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS12120 fe00a61208af2b6b2e671102c316417e 398 Gene3D G3DSA:3.40.50.2000 196 366 3.1E-32 T 09-03-2017 ARZXY2_RS12120 fe00a61208af2b6b2e671102c316417e 398 Pfam PF13439 Glycosyltransferase Family 4 23 199 3.5E-21 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS12120 fe00a61208af2b6b2e671102c316417e 398 SUPERFAMILY SSF53756 12 390 1.07E-75 T 09-03-2017 ARZXY2_RS12845 07661a4fce187dc139a7478a0a38e235 598 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 190 260 3.5E-10 T 09-03-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 ARZXY2_RS12845 07661a4fce187dc139a7478a0a38e235 598 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 407 597 9.6E-21 T 09-03-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 ARZXY2_RS14890 19dc5dac25c36e7c56363fdb7629c98a 180 Pfam PF02542 YgbB family 10 162 2.2E-45 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 ARZXY2_RS14890 19dc5dac25c36e7c56363fdb7629c98a 180 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 10 163 6.4E-43 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 ARZXY2_RS14890 19dc5dac25c36e7c56363fdb7629c98a 180 Gene3D G3DSA:3.30.1330.50 8 164 8.7E-54 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 ARZXY2_RS14890 19dc5dac25c36e7c56363fdb7629c98a 180 SUPERFAMILY SSF69765 8 164 2.35E-49 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 ARZXY2_RS14890 19dc5dac25c36e7c56363fdb7629c98a 180 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 9 164 30.07 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 SUPERFAMILY SSF102114 120 354 4.58E-54 T 09-03-2017 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 431 63.91 T 09-03-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 Pfam PF00919 Uncharacterized protein family UPF0004 1 89 1.2E-21 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 Pfam PF04055 Radical SAM superfamily 136 307 9.7E-29 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 427 5.7E-143 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 Gene3D G3DSA:3.80.30.20 132 362 1.5E-79 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 Pfam PF01938 TRAM domain 362 428 6.7E-5 T 09-03-2017 IPR002792 TRAM domain ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 SMART SM00729 132 350 2.0E-54 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS11375 54069c317fee43030b214b48f4f2403d 480 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 426 7.2E-131 T 09-03-2017 ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 Gene3D G3DSA:2.40.50.140 2 68 2.8E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 SUPERFAMILY SSF50249 2 68 3.92E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 60 3.3E-13 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 SMART SM00357 3 65 9.4E-16 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 PRINTS PR00050 Cold shock protein signature 38 56 2.3E-9 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 PRINTS PR00050 Cold shock protein signature 4 19 2.3E-9 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS14255 b69da81dc2e9f52b48d196357b5e0d44 127 PRINTS PR00050 Cold shock protein signature 24 33 2.3E-9 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Gene3D G3DSA:3.90.660.10 58 133 7.8E-31 T 09-03-2017 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Gene3D G3DSA:3.90.660.10 347 449 7.8E-31 T 09-03-2017 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Pfam PF01593 Flavin containing amine oxidoreductase 39 513 3.6E-48 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Gene3D G3DSA:3.50.50.60 225 343 7.7E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Gene3D G3DSA:3.50.50.60 483 522 7.7E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 SUPERFAMILY SSF51905 29 358 3.8E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 SUPERFAMILY SSF51905 480 521 3.8E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 Gene3D G3DSA:3.50.50.60 27 57 2.4E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13305 49814f198da96152016354df071efea0 543 SUPERFAMILY SSF54373 343 458 8.5E-28 T 09-03-2017 ARZXY2_RS04740 c5170b751fa9a07c26b5f433673fa095 230 Pfam PF13559 Domain of unknown function (DUF4129) 140 206 6.7E-11 T 09-03-2017 IPR025403 Domain of unknown function DUF4129 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 PIRSF PIRSF004491 2 326 2.3E-91 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 Pfam PF01687 Riboflavin kinase 195 324 2.6E-31 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 Gene3D G3DSA:3.40.50.620 4 190 3.3E-63 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 SUPERFAMILY SSF52374 17 186 1.85E-30 T 09-03-2017 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 SUPERFAMILY SSF82114 185 324 1.2E-37 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 Pfam PF06574 FAD synthetase 17 159 3.5E-49 T 09-03-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 324 2.2E-67 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 Gene3D G3DSA:2.40.30.30 191 325 4.3E-42 T 09-03-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 ARZXY2_RS11515 723e56936a977191d40929f480893a2a 327 SMART SM00904 194 325 1.7E-49 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.40.50.300 513 634 7.6E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.40.50.300 855 972 6.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.40.50.300 644 707 6.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.40.50.300 31 80 7.6E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 SMART SM00382 667 932 0.0038 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 ProSitePatterns PS00211 ABC transporters family signature. 522 536 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 SUPERFAMILY SSF52540 465 604 6.15E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 SUPERFAMILY SSF52540 39 233 6.15E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 33 959 0.0 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:1.10.8.280 319 441 2.3E-39 T 09-03-2017 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Hamap MF_00205 UvrABC system protein A [uvrA]. 30 974 22.62 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 ProSitePatterns PS00211 ABC transporters family signature. 864 878 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 SUPERFAMILY SSF52540 652 946 2.54E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:1.20.1580.10 283 317 5.2E-52 T 09-03-2017 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:1.20.1580.10 120 158 5.2E-52 T 09-03-2017 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:1.20.1580.10 442 512 5.2E-52 T 09-03-2017 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.30.1490.20 229 268 2.1E-27 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:3.30.1490.20 159 182 2.1E-27 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Gene3D G3DSA:1.20.1580.10 728 854 2.8E-54 T 09-03-2017 ARZXY2_RS09115 4e434bd733a83a5a8ae2ae977a7f2cc0 975 Pfam PF00005 ABC transporter 658 894 8.2E-11 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 SUPERFAMILY SSF46785 3 150 2.14E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 SMART SM00347 32 135 2.2E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 4.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 4.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 4.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 4.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 Gene3D G3DSA:1.10.10.10 1 151 8.7E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20600 54e75bd128ea97e6944cdb0b3b3abce8 159 Pfam PF12802 MarR family 44 97 3.6E-10 T 09-03-2017 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 SUPERFAMILY SSF55874 394 555 3.27E-47 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 447 555 6.2E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Gene3D G3DSA:1.10.287.130 330 397 2.5E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Pfam PF00512 His Kinase A (phospho-acceptor) domain 337 397 9.6E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Gene3D G3DSA:3.30.450.20 208 329 9.2E-8 T 09-03-2017 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 536 1.8E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 555 1.8E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 511 1.8E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 497 1.8E-17 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 SUPERFAMILY SSF55785 200 329 6.28E-7 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 SMART SM00387 446 556 2.0E-33 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Pfam PF08448 PAS fold 220 332 5.3E-5 T 09-03-2017 IPR013656 PAS fold-4 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 SMART SM00388 337 403 3.0E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 SUPERFAMILY SSF47384 324 398 9.42E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS13925 3be0bd7eacfc75f87fa8ecace988b40d 556 Gene3D G3DSA:3.30.565.10 408 555 1.3E-46 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS08955 57316f68ee99a7ffc64d03408aaca53b 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS08955 57316f68ee99a7ffc64d03408aaca53b 240 Gene3D G3DSA:3.40.50.300 3 226 6.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08955 57316f68ee99a7ffc64d03408aaca53b 240 SUPERFAMILY SSF52540 22 218 7.48E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08955 57316f68ee99a7ffc64d03408aaca53b 240 Pfam PF00005 ABC transporter 25 168 1.0E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08955 57316f68ee99a7ffc64d03408aaca53b 240 SMART SM00382 33 213 2.9E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 Gene3D G3DSA:1.10.10.10 18 91 8.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 SUPERFAMILY SSF55781 83 263 1.44E-34 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 Gene3D G3DSA:3.30.450.40 101 263 4.5E-39 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 SMART SM00346 18 97 4.2E-18 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 SUPERFAMILY SSF46785 20 91 1.74E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 Pfam PF01614 Bacterial transcriptional regulator 135 259 1.7E-20 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS07385 1569c358b4c4e1a380ab411228ab66e8 264 Pfam PF09339 IclR helix-turn-helix domain 20 71 1.1E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS08780 651789e054bb51d9f95dcea6a23114c7 369 Gene3D G3DSA:3.30.360.10 156 352 4.7E-25 T 09-03-2017 ARZXY2_RS08780 651789e054bb51d9f95dcea6a23114c7 369 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 20 138 2.2E-25 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS08780 651789e054bb51d9f95dcea6a23114c7 369 SUPERFAMILY SSF55347 145 265 3.49E-19 T 09-03-2017 ARZXY2_RS08780 651789e054bb51d9f95dcea6a23114c7 369 Gene3D G3DSA:3.40.50.720 19 155 2.2E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08780 651789e054bb51d9f95dcea6a23114c7 369 SUPERFAMILY SSF51735 18 167 7.69E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 157 2.2E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 Gene3D G3DSA:1.10.1740.10 4 96 5.3E-20 T 09-03-2017 ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 SUPERFAMILY SSF88659 97 159 2.62E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 Gene3D G3DSA:1.10.10.10 101 160 3.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 SUPERFAMILY SSF88946 4 90 7.46E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 Pfam PF04542 Sigma-70 region 2 11 77 3.6E-16 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS00950 a8fb9c1ed0a2499139332cd4aa2e270b 165 Pfam PF04545 Sigma-70, region 4 107 155 7.5E-10 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 SUPERFAMILY SSF54211 254 447 1.23E-34 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 SUPERFAMILY SSF56719 451 690 1.15E-75 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 140 5.3E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Gene3D G3DSA:3.40.50.670 461 681 1.1E-75 T 09-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Pfam PF00204 DNA gyrase B 254 447 1.8E-50 T 09-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 SUPERFAMILY SSF55874 7 234 3.54E-58 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Gene3D G3DSA:3.30.565.10 7 234 1.8E-80 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Pfam PF01751 Toprim domain 476 583 1.7E-15 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 561 578 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 477 491 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 543 559 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 71 84 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 581 593 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 36 51 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 632 648 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR00418 DNA topoisomerase II family signature 320 333 2.5E-61 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 ProSitePatterns PS00177 DNA topoisomerase II signature. 479 487 - T 09-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Gene3D G3DSA:3.30.230.10 253 448 1.9E-44 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 SMART SM00387 32 199 8.0E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 631 688 5.6E-25 T 09-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 431 451 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 669 685 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 365 381 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 7 17 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 253 275 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 220 233 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 527 536 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 PRINTS PR01159 DNA gyrase subunit B signature 653 665 8.0E-30 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 ARZXY2_RS10640 90bee6f55136fea262b9d6057f1ecf88 702 SMART SM00433 36 693 3.4E-254 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 ARZXY2_RS04865 d3929ef9d7d1cbfbe770eda2f5f8a9e4 285 Pfam PF01061 ABC-2 type transporter 26 237 2.7E-21 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS04865 d3929ef9d7d1cbfbe770eda2f5f8a9e4 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 154 178 4.9E-6 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS04865 d3929ef9d7d1cbfbe770eda2f5f8a9e4 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 77 99 4.9E-6 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS04865 d3929ef9d7d1cbfbe770eda2f5f8a9e4 285 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 4.9E-6 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13450 b8cbc845676002b380b87284aaa56342 147 Pfam PF13411 MerR HTH family regulatory protein 41 107 1.5E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13450 b8cbc845676002b380b87284aaa56342 147 Gene3D G3DSA:1.10.1660.10 41 134 1.6E-20 T 09-03-2017 ARZXY2_RS13450 b8cbc845676002b380b87284aaa56342 147 SMART SM00422 41 109 8.4E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13450 b8cbc845676002b380b87284aaa56342 147 SUPERFAMILY SSF46955 41 126 3.53E-18 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS13635 d2116bd96aa1dd0cd4dfdcbc0104b379 248 SUPERFAMILY SSF51182 26 131 4.26E-16 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS13635 d2116bd96aa1dd0cd4dfdcbc0104b379 248 Gene3D G3DSA:2.60.120.10 10 97 5.4E-14 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS13635 d2116bd96aa1dd0cd4dfdcbc0104b379 248 Pfam PF07883 Cupin domain 24 90 1.1E-10 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS15640 676939debf65b293fd68539cf37c86e5 332 Gene3D G3DSA:3.20.20.150 3 315 5.1E-75 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS15640 676939debf65b293fd68539cf37c86e5 332 Pfam PF01261 Xylose isomerase-like TIM barrel 22 272 1.1E-38 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS15640 676939debf65b293fd68539cf37c86e5 332 SUPERFAMILY SSF51658 7 316 8.25E-58 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS15640 676939debf65b293fd68539cf37c86e5 332 Pfam PF07582 AP endonuclease family 2 C terminus 274 328 5.4E-22 T 09-03-2017 IPR011418 AP endonuclease, family 2, C-terminal ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 Pfam PF01715 IPP transferase 46 286 3.7E-77 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 SUPERFAMILY SSF52540 13 164 3.19E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 Gene3D G3DSA:3.40.50.300 12 177 2.2E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 13 293 5.2E-81 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 Gene3D G3DSA:1.10.287.890 202 283 3.8E-27 T 09-03-2017 ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 SUPERFAMILY SSF52540 175 264 1.67E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 SUPERFAMILY SSF52540 12 80 1.67E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11370 8d3a2bf5729bbbff0fa47ec81ce4d717 307 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 13 302 27.872 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 SUPERFAMILY SSF46785 13 86 7.29E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 SUPERFAMILY SSF55781 78 261 4.64E-40 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 SMART SM00346 13 103 2.6E-9 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 Gene3D G3DSA:1.10.10.10 11 85 7.8E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 Pfam PF01614 Bacterial transcriptional regulator 132 258 3.0E-19 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 Gene3D G3DSA:3.30.450.40 86 264 6.0E-45 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS16800 924155734443d5841e10b9e0613ebd23 266 Pfam PF09339 IclR helix-turn-helix domain 15 62 3.1E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS08300 0ace8fe5515f99413ced9bd339549c92 361 SUPERFAMILY SSF52540 102 303 8.35E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08300 0ace8fe5515f99413ced9bd339549c92 361 Gene3D G3DSA:3.40.50.300 135 338 4.4E-97 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08300 0ace8fe5515f99413ced9bd339549c92 361 Pfam PF02562 PhoH-like protein 136 338 1.5E-92 T 09-03-2017 IPR003714 PhoH-like protein GO:0005524 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 30 576 1.0E-274 T 09-03-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Gene3D G3DSA:3.20.20.80 466 480 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Gene3D G3DSA:3.20.20.80 33 130 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Gene3D G3DSA:3.20.20.80 206 433 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Gene3D G3DSA:2.60.40.1180 487 576 1.3E-12 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Pfam PF16657 Maltogenic Amylase, C-terminal domain 487 573 4.0E-21 T 09-03-2017 IPR032091 Maltogenic Amylase, C-terminal ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Pfam PF00128 Alpha amylase, catalytic domain 54 408 2.9E-78 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 SUPERFAMILY SSF51445 377 484 4.04E-129 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 SUPERFAMILY SSF51445 28 350 4.04E-129 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 Gene3D G3DSA:3.90.400.10 131 198 2.9E-23 T 09-03-2017 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 SUPERFAMILY SSF51011 490 576 6.0E-14 T 09-03-2017 ARZXY2_RS14835 4a509106f447efe9096b214459c47385 598 SMART SM00642 39 439 1.3E-110 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 Pfam PF05195 Aminopeptidase P, N-terminal domain 60 190 1.1E-19 T 09-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 SUPERFAMILY SSF55920 252 519 7.07E-65 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 SMART SM01011 53 197 1.8E-35 T 09-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 Gene3D G3DSA:3.40.350.10 56 255 1.6E-36 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 SUPERFAMILY SSF53092 57 251 3.14E-26 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 Pfam PF00557 Metallopeptidase family M24 257 497 1.4E-51 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 431 443 - T 09-03-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site ARZXY2_RS04375 bb01dcea12b25a29d7c879bf550535f9 525 Gene3D G3DSA:3.90.230.10 256 518 2.9E-68 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 8 154 4.7E-60 T 09-03-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 Pfam PF02502 Ribose/Galactose Isomerase 9 149 1.1E-44 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 PIRSF PIRSF005384 7 156 4.5E-44 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 9 153 2.2E-32 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 Gene3D G3DSA:3.40.1400.10 8 156 6.3E-49 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS13810 5ce992cb9254baa3a6e6818f07be205f 160 SUPERFAMILY SSF89623 6 153 7.98E-47 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS15395 62aa350cd5243d8038dd621bc99e7d89 215 SUPERFAMILY SSF102588 9 207 2.09E-47 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS15395 62aa350cd5243d8038dd621bc99e7d89 215 Gene3D G3DSA:3.40.50.10320 9 207 3.5E-53 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS15395 62aa350cd5243d8038dd621bc99e7d89 215 Pfam PF02585 GlcNAc-PI de-N-acetylase 13 128 6.5E-25 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 Gene3D G3DSA:1.10.260.40 13 64 6.0E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 Pfam PF13377 Periplasmic binding protein-like domain 178 341 4.1E-35 T 09-03-2017 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 Gene3D G3DSA:3.40.50.2300 182 321 2.6E-37 T 09-03-2017 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 SUPERFAMILY SSF53822 76 342 4.93E-49 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 SUPERFAMILY SSF47413 13 71 2.06E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 Gene3D G3DSA:3.40.50.2300 65 181 1.9E-23 T 09-03-2017 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 SMART SM00354 13 85 1.4E-9 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00520 4a75d35519a04004e2d7293107ff2ae7 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 60 5.1E-10 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS06130 f83fcd93362a57abf4defe1114e79c1e 99 Gene3D G3DSA:3.40.50.450 29 98 2.4E-18 T 09-03-2017 ARZXY2_RS06130 f83fcd93362a57abf4defe1114e79c1e 99 SUPERFAMILY SSF102405 17 98 1.01E-19 T 09-03-2017 ARZXY2_RS13020 be2f88045e31531789721a87e483f971 212 Gene3D G3DSA:1.20.1540.10 57 198 1.3E-16 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ARZXY2_RS13020 be2f88045e31531789721a87e483f971 212 SUPERFAMILY SSF144091 31 201 3.4E-28 T 09-03-2017 ARZXY2_RS13020 be2f88045e31531789721a87e483f971 212 Pfam PF01694 Rhomboid family 65 200 1.7E-21 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 ARZXY2_RS20315 3d6fdc788897e9e5298a0e1125dac3c7 167 Pfam PF04306 Protein of unknown function (DUF456) 23 159 9.8E-27 T 09-03-2017 IPR007403 Protein of unknown function DUF456 ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 3.4E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 SUPERFAMILY SSF46785 8 75 1.51E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 Pfam PF07729 FCD domain 84 206 4.4E-26 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 SMART SM00895 81 207 1.4E-12 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 SMART SM00345 13 71 4.7E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 Gene3D G3DSA:1.10.10.10 8 72 4.9E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 Gene3D G3DSA:1.20.120.530 75 214 2.1E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS09370 ca7a7fe4baa48f797df44ad5d46dab1d 219 SUPERFAMILY SSF48008 84 214 1.33E-19 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 SUPERFAMILY SSF69618 26 286 6.93E-53 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 SUPERFAMILY SSF46894 294 382 1.56E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 SMART SM00862 312 381 1.5E-13 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 Pfam PF00486 Transcriptional regulatory protein, C terminal 312 381 1.5E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 Gene3D G3DSA:3.40.50.10090 23 152 4.2E-27 T 09-03-2017 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 Gene3D G3DSA:3.40.50.10090 153 286 1.0E-32 T 09-03-2017 ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 Gene3D G3DSA:1.10.10.10 293 382 1.6E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12595 8e6c0f1f7fdb2d812a7cb4f10bff73aa 383 Pfam PF02602 Uroporphyrinogen-III synthase HemD 39 279 6.2E-41 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS10315 b31b5e93efe5f5cca792d5b13ac84f2f 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 22 155 7.9E-50 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10315 b31b5e93efe5f5cca792d5b13ac84f2f 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 22 155 5.6E-40 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10315 b31b5e93efe5f5cca792d5b13ac84f2f 161 Gene3D G3DSA:3.40.50.960 18 160 2.9E-57 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10315 b31b5e93efe5f5cca792d5b13ac84f2f 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 17 160 27.313 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10315 b31b5e93efe5f5cca792d5b13ac84f2f 161 SUPERFAMILY SSF52121 18 160 1.1E-52 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 Gene3D G3DSA:3.40.50.720 963 1074 1.9E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 Gene3D G3DSA:3.40.50.720 1131 1223 1.9E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 SUPERFAMILY SSF53223 774 895 2.3E-23 T 09-03-2017 ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 SUPERFAMILY SSF53223 922 962 2.3E-23 T 09-03-2017 ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 Gene3D G3DSA:3.40.192.10 813 934 9.0E-4 T 09-03-2017 ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 SUPERFAMILY SSF51735 1106 1304 6.56E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 SUPERFAMILY SSF51735 966 1068 6.56E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 58 1628 0.0 T 09-03-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 ARZXY2_RS16770 557b2ac4ed23dafd1d6f4b0c2727fb08 1633 PIRSF PIRSF036761 6 1633 0.0 T 09-03-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 30.098 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 09-03-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 Pfam PF00551 Formyl transferase 1 181 2.6E-55 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 Gene3D G3DSA:3.40.50.170 1 186 7.8E-70 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 SUPERFAMILY SSF53328 1 185 4.19E-61 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS13420 2be1384b5a25fd430c7b9139e7f1028a 191 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 185 8.3E-70 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 124 27.542 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 Gene3D G3DSA:2.40.50.100 7 122 2.8E-44 T 09-03-2017 ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 SUPERFAMILY SSF51230 5 122 2.75E-38 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 Pfam PF01597 Glycine cleavage H-protein 8 121 4.7E-40 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS19595 197c64de3d35f59b67350f7a00644207 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 121 1.6E-42 T 09-03-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 ARZXY2_RS17425 58a9f53e7d387d722392f5e0816e36d8 139 Gene3D G3DSA:3.10.180.10 2 129 1.2E-27 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS17425 58a9f53e7d387d722392f5e0816e36d8 139 SUPERFAMILY SSF54593 3 128 3.22E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 SMART SM00354 3 74 5.0E-25 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 Gene3D G3DSA:3.40.50.2300 57 191 5.5E-26 T 09-03-2017 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 SUPERFAMILY SSF53822 62 319 4.32E-41 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 SUPERFAMILY SSF47413 4 62 6.83E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 Pfam PF13377 Periplasmic binding protein-like domain 195 319 3.0E-18 T 09-03-2017 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 Gene3D G3DSA:3.40.50.2300 192 319 1.6E-31 T 09-03-2017 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 Gene3D G3DSA:1.10.260.40 5 56 9.2E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 09-03-2017 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 7.3E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 5.1E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00280 6ee2bce4b26cd86d564f3fbb07a1073b 345 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 5.1E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 SUPERFAMILY SSF51905 1 190 2.59E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 SUPERFAMILY SSF51905 292 347 2.59E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 Gene3D G3DSA:3.30.9.10 49 112 5.3E-4 T 09-03-2017 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 Gene3D G3DSA:3.50.50.60 113 189 3.6E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 Gene3D G3DSA:3.50.50.60 292 348 3.6E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 Gene3D G3DSA:3.50.50.60 1 48 3.6E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS08475 fdbaeda33f00c0b98c13753948ce31ba 350 Pfam PF01266 FAD dependent oxidoreductase 1 328 1.8E-30 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS13400 4cb069f02deeebc678366ff8542d991e 315 Gene3D G3DSA:3.30.420.40 82 127 3.0E-4 T 09-03-2017 ARZXY2_RS13400 4cb069f02deeebc678366ff8542d991e 315 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 67 295 2.5E-16 T 09-03-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 ARZXY2_RS13400 4cb069f02deeebc678366ff8542d991e 315 SUPERFAMILY SSF53067 118 297 9.16E-34 T 09-03-2017 ARZXY2_RS12695 4fecbc47bbb1559b1af6f25a295a79e9 481 Gene3D G3DSA:3.40.50.2000 201 358 2.0E-23 T 09-03-2017 ARZXY2_RS12695 4fecbc47bbb1559b1af6f25a295a79e9 481 SUPERFAMILY SSF53756 18 376 1.41E-60 T 09-03-2017 ARZXY2_RS12695 4fecbc47bbb1559b1af6f25a295a79e9 481 Pfam PF13439 Glycosyltransferase Family 4 32 190 9.1E-14 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS12695 4fecbc47bbb1559b1af6f25a295a79e9 481 Pfam PF00534 Glycosyl transferases group 1 199 332 1.1E-28 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS04565 10ce65978db86910dc34461d4903b912 475 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 72 424 4.1E-114 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 ARZXY2_RS04565 10ce65978db86910dc34461d4903b912 475 SUPERFAMILY SSF55486 71 424 4.1E-111 T 09-03-2017 ARZXY2_RS04565 10ce65978db86910dc34461d4903b912 475 Pfam PF10103 Zinicin-like metallopeptidase 72 421 3.4E-120 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 ARZXY2_RS23050 a1e162aeea5073f883cff4eaa96b85ed 108 Pfam PF01988 VIT family 3 108 1.4E-19 T 09-03-2017 IPR008217 Ccc1 family ARZXY2_RS00395 023b7c5504dfee214415a9ea79e3dbdc 223 Pfam PF00293 NUDIX domain 15 172 9.5E-10 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS00395 023b7c5504dfee214415a9ea79e3dbdc 223 Gene3D G3DSA:3.90.79.10 94 183 2.2E-19 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS00395 023b7c5504dfee214415a9ea79e3dbdc 223 Gene3D G3DSA:3.90.79.10 13 60 2.2E-19 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS00395 023b7c5504dfee214415a9ea79e3dbdc 223 SUPERFAMILY SSF55811 12 60 2.39E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS00395 023b7c5504dfee214415a9ea79e3dbdc 223 SUPERFAMILY SSF55811 94 182 2.39E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11920 61b08c313e2c8b3200d607bb2a3386a4 88 Pfam PF01844 HNH endonuclease 19 74 1.2E-4 T 09-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 ARZXY2_RS01020 1117361f703fe9472935aed5e0a2e11c 131 SUPERFAMILY SSF103481 19 114 5.23E-10 T 09-03-2017 ARZXY2_RS01020 1117361f703fe9472935aed5e0a2e11c 131 Pfam PF00893 Small Multidrug Resistance protein 16 105 7.5E-16 T 09-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 ARZXY2_RS02420 18b3a919d0979a5ce02f522c7a87c279 315 Gene3D G3DSA:3.40.50.10330 7 101 1.3E-7 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS02420 18b3a919d0979a5ce02f522c7a87c279 315 SUPERFAMILY SSF111331 8 301 5.23E-69 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS02420 18b3a919d0979a5ce02f522c7a87c279 315 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 12 301 6.6E-45 T 09-03-2017 IPR005218 Diacylglycerol/lipid kinase ARZXY2_RS02420 18b3a919d0979a5ce02f522c7a87c279 315 SMART SM00046 7 138 5.9E-4 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS02420 18b3a919d0979a5ce02f522c7a87c279 315 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 129 1.2E-21 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS15705 2267b8d41d4c1b71eab387d8a00a232c 233 SUPERFAMILY SSF52833 1 210 2.64E-44 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS15705 2267b8d41d4c1b71eab387d8a00a232c 233 Gene3D G3DSA:3.40.30.10 1 209 2.2E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS15705 2267b8d41d4c1b71eab387d8a00a232c 233 Pfam PF01323 DSBA-like thioredoxin domain 2 204 1.1E-42 T 09-03-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 Pfam PF00501 AMP-binding enzyme 84 303 1.3E-13 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 Pfam PF14535 AMP-binding enzyme C-terminal domain 350 445 7.2E-22 T 09-03-2017 IPR028154 AMP-dependent ligase, C-terminal ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 24 445 7.7E-199 T 09-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 SUPERFAMILY SSF56801 32 410 1.7E-60 T 09-03-2017 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 Gene3D G3DSA:3.40.50.980 98 257 3.0E-14 T 09-03-2017 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 PIRSF PIRSF006444 13 447 8.2E-190 T 09-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 ARZXY2_RS02320 63bea0a15524b1f35093a17d33531d74 448 Gene3D G3DSA:3.30.300.30 340 445 1.4E-30 T 09-03-2017 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 Gene3D G3DSA:3.40.50.2300 193 324 8.5E-43 T 09-03-2017 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 Gene3D G3DSA:1.10.260.40 24 75 6.2E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 Gene3D G3DSA:3.40.50.2300 76 192 7.5E-39 T 09-03-2017 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 SUPERFAMILY SSF47413 24 81 4.13E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 SUPERFAMILY SSF53822 82 344 2.16E-61 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 Pfam PF13377 Periplasmic binding protein-like domain 186 343 6.6E-34 T 09-03-2017 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 SMART SM00354 23 93 1.2E-28 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16225 b34a2aa5d016f3dc2c4ffccb7ffd3e90 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 25 70 5.4E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 PIRSF PIRSF000535 1 321 1.4E-59 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 SUPERFAMILY SSF53613 1 311 2.81E-50 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 Gene3D G3DSA:3.40.1190.20 33 313 1.0E-64 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 Pfam PF00294 pfkB family carbohydrate kinase 21 309 4.4E-35 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS17230 8d7809439f12ee60871546d9db1f49f0 328 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 316 5.0E-82 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 ARZXY2_RS09860 1604426ab5376269c39ab3bdafb0c456 120 Pfam PF03779 SPW repeat 60 103 7.4E-6 T 09-03-2017 IPR005530 SPW repeat ARZXY2_RS14060 a64c53fd7705cb5c3c05477f1cd20380 289 Pfam PF01261 Xylose isomerase-like TIM barrel 22 238 3.5E-38 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14060 a64c53fd7705cb5c3c05477f1cd20380 289 SUPERFAMILY SSF51658 1 289 4.06E-54 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14060 a64c53fd7705cb5c3c05477f1cd20380 289 Gene3D G3DSA:3.20.20.150 1 285 6.9E-52 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS03150 cc8a55f07b2bfb2fc4b3701e00181ea9 218 Gene3D G3DSA:2.40.33.20 9 215 3.2E-65 T 09-03-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like ARZXY2_RS03150 cc8a55f07b2bfb2fc4b3701e00181ea9 218 SUPERFAMILY SSF50800 9 215 7.85E-54 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain ARZXY2_RS03150 cc8a55f07b2bfb2fc4b3701e00181ea9 218 Pfam PF03473 MOSC domain 52 163 2.1E-22 T 09-03-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 Gene3D G3DSA:3.50.50.60 159 369 5.1E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 Gene3D G3DSA:3.50.50.60 491 656 2.8E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 326 350 2.4E-6 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 183 2.4E-6 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 SUPERFAMILY SSF51905 160 372 2.47E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 Pfam PF00743 Flavin-binding monooxygenase-like 163 365 8.7E-17 T 09-03-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 SUPERFAMILY SSF51905 449 651 4.53E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 330 348 2.4E-5 T 09-03-2017 ARZXY2_RS19160 c2619d0e14cd2c912a21725377c2524c 660 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 181 2.4E-5 T 09-03-2017 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Pfam PF13089 Polyphosphate kinase N-terminal domain 57 162 2.1E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 SUPERFAMILY SSF140356 54 156 3.92E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Gene3D G3DSA:3.30.870.10 559 740 2.3E-69 T 09-03-2017 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 SUPERFAMILY SSF56024 383 556 9.64E-56 T 09-03-2017 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 PIRSF PIRSF015589 34 749 4.8E-275 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Pfam PF02503 Polyphosphate kinase middle domain 173 373 8.3E-63 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Hamap MF_00347 Polyphosphate kinase [ppk]. 54 740 33.458 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Pfam PF13090 Polyphosphate kinase C-terminal domain 388 736 3.9E-153 T 09-03-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 56 726 5.1E-253 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Gene3D G3DSA:3.30.1840.10 159 353 1.3E-69 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 Gene3D G3DSA:3.30.870.10 380 558 2.7E-78 T 09-03-2017 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 SUPERFAMILY SSF143724 160 366 9.42E-63 T 09-03-2017 ARZXY2_RS03305 f52c65645e40a5039699834cb30e6a03 749 SUPERFAMILY SSF56024 559 737 1.41E-65 T 09-03-2017 ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 SMART SM00014 65 176 1.2E-16 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 Pfam PF00781 Diacylglycerol kinase catalytic domain 218 318 9.6E-14 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 SUPERFAMILY SSF48317 12 189 4.19E-33 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 Gene3D G3DSA:3.40.50.10330 258 308 6.1E-4 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 Gene3D G3DSA:3.40.50.10330 371 390 6.1E-4 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 SUPERFAMILY SSF111331 217 496 6.32E-41 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 Gene3D G3DSA:1.20.144.10 12 180 9.4E-28 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 Pfam PF01569 PAP2 superfamily 71 181 3.8E-16 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18720 93cf18a9652deb9f94c67ef514cfb220 501 SMART SM00046 203 325 9.9E-5 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Gene3D G3DSA:2.30.30.30 3 63 2.4E-31 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.3E-25 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 SMART SM00841 129 184 5.2E-33 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 59 1.0E-26 T 09-03-2017 IPR013185 Translation elongation factor, KOW-like ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Gene3D G3DSA:2.40.50.140 128 185 6.7E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 SUPERFAMILY SSF50249 65 126 1.59E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 PIRSF PIRSF005901 1 186 1.5E-67 T 09-03-2017 IPR020599 Translation elongation factor P/YeiP ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Gene3D G3DSA:2.40.50.140 65 126 5.7E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 SUPERFAMILY SSF50104 2 63 2.86E-20 T 09-03-2017 IPR008991 Translation protein SH3-like domain ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 SMART SM01185 67 121 1.3E-27 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.35 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 3.0E-78 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 3.0E-21 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 09-03-2017 IPR013852 Translation elongation factor P/YeiP, conserved site ARZXY2_RS08100 e3a3cede6d9b4477336450c69769efe3 187 SUPERFAMILY SSF50249 129 185 9.59E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 SUPERFAMILY SSF54593 16 269 3.75E-30 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 Gene3D G3DSA:3.10.180.10 175 287 1.8E-20 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 129 5.5E-6 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 176 268 4.0E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 ProSitePatterns PS00934 Glyoxalase I signature 1. 179 200 - T 09-03-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 ARZXY2_RS06995 3f4d3833a17cd54e5dfd704ff7d9a714 290 Gene3D G3DSA:3.10.180.10 14 150 1.7E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 SUPERFAMILY SSF81330 10 126 7.06E-25 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 2.6E-6 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.6E-6 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 2.6E-6 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 131 4.4E-26 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS19575 d5b6f0fca52c330bf664181e64b60cb2 146 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 130 2.2E-36 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 93 298 8.1E-68 T 09-03-2017 ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 Gene3D G3DSA:3.40.50.1000 160 296 7.8E-44 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 SUPERFAMILY SSF56784 97 300 9.9E-44 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 Gene3D G3DSA:1.10.150.210 108 159 4.6E-25 T 09-03-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 Pfam PF12710 haloacid dehalogenase-like hydrolase 100 266 6.9E-23 T 09-03-2017 ARZXY2_RS08900 3345a7000e0e3fdcd7a3f4aa288e4130 303 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 98 266 1.7E-30 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 ARZXY2_RS07535 3e780e61133bfcebceb666dfbede257e 157 Pfam PF01152 Bacterial-like globin 34 151 1.8E-32 T 09-03-2017 IPR001486 Truncated hemoglobin GO:0019825 ARZXY2_RS07535 3e780e61133bfcebceb666dfbede257e 157 SUPERFAMILY SSF46458 33 154 2.88E-35 T 09-03-2017 IPR009050 Globin-like ARZXY2_RS07535 3e780e61133bfcebceb666dfbede257e 157 Gene3D G3DSA:1.10.490.10 33 153 9.8E-42 T 09-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 ARZXY2_RS07535 3e780e61133bfcebceb666dfbede257e 157 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 81 105 - T 09-03-2017 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 ARZXY2_RS02300 5a9abad9745f436a8e4ff7c2993ec33d 330 SUPERFAMILY SSF53448 10 231 1.53E-37 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02300 5a9abad9745f436a8e4ff7c2993ec33d 330 Gene3D G3DSA:3.90.550.10 9 235 8.8E-39 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02300 5a9abad9745f436a8e4ff7c2993ec33d 330 Pfam PF00535 Glycosyl transferase family 2 11 130 4.2E-22 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS14870 93dfbd0d7482b4693d2aec57a198aaf4 269 Pfam PF00795 Carbon-nitrogen hydrolase 2 257 1.8E-35 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS14870 93dfbd0d7482b4693d2aec57a198aaf4 269 Gene3D G3DSA:3.60.110.10 1 267 2.4E-64 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS14870 93dfbd0d7482b4693d2aec57a198aaf4 269 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 09-03-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site ARZXY2_RS14870 93dfbd0d7482b4693d2aec57a198aaf4 269 SUPERFAMILY SSF56317 1 266 4.58E-59 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 ARZXY2_RS02210 5b88d78db6624879569e383c8fe89dcd 292 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 21.866 T 09-03-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 ARZXY2_RS02210 5b88d78db6624879569e383c8fe89dcd 292 Pfam PF01040 UbiA prenyltransferase family 20 264 3.8E-38 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 ARZXY2_RS02210 5b88d78db6624879569e383c8fe89dcd 292 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 286 2.0E-85 T 09-03-2017 ARZXY2_RS02210 5b88d78db6624879569e383c8fe89dcd 292 PIRSF PIRSF005355 1 292 2.1E-91 T 09-03-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 3 735 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 SUPERFAMILY SSF53659 2 738 0.0 T 09-03-2017 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 Gene3D G3DSA:3.40.718.10 337 360 2.7E-35 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 Gene3D G3DSA:3.40.718.10 184 285 2.7E-35 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 Gene3D G3DSA:3.40.718.10 536 641 2.7E-35 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 739 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 ARZXY2_RS13385 33fbb2def818d250b4cc747bc26d3ced 739 PIRSF PIRSF009407 1 739 0.0 T 09-03-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:1.10.10.470 504 590 3.8E-20 T 09-03-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 SUPERFAMILY SSF51445 4 682 1.06E-121 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Pfam PF00128 Alpha amylase, catalytic domain 23 238 6.7E-17 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:3.30.1590.10 94 210 4.2E-37 T 09-03-2017 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:3.20.20.80 224 298 3.3E-68 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:3.20.20.80 3 93 3.3E-68 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:3.20.20.80 462 502 3.3E-68 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:3.20.20.80 594 706 3.3E-68 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 767 2.3E-271 T 09-03-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 SMART SM00642 11 675 1.1E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03775 e60f970678764d887c85a7811dabf767 770 Gene3D G3DSA:1.10.150.200 323 428 5.8E-14 T 09-03-2017 ARZXY2_RS19225 042b35c592b9af254306a84f1933ddd4 333 Gene3D G3DSA:3.40.50.10440 12 183 8.9E-61 T 09-03-2017 ARZXY2_RS19225 042b35c592b9af254306a84f1933ddd4 333 SUPERFAMILY SSF82549 11 332 1.7E-101 T 09-03-2017 ARZXY2_RS19225 042b35c592b9af254306a84f1933ddd4 333 Gene3D G3DSA:3.30.1180.20 186 332 4.0E-45 T 09-03-2017 ARZXY2_RS19225 042b35c592b9af254306a84f1933ddd4 333 Pfam PF02733 Dak1 domain 18 327 2.4E-108 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS04205 23f5374848dca1af1b83c74f91e74daf 111 Pfam PF01934 Protein of unknown function DUF86 45 109 2.6E-12 T 09-03-2017 IPR008201 Protein of unknown function DUF86 ARZXY2_RS04205 23f5374848dca1af1b83c74f91e74daf 111 Gene3D G3DSA:1.20.120.580 72 110 1.6E-4 T 09-03-2017 ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 Pfam PF00905 Penicillin binding protein transpeptidase domain 365 658 6.4E-21 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 SUPERFAMILY SSF56601 301 724 1.5E-63 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 SUPERFAMILY SSF56601 246 268 1.5E-63 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 Pfam PF00912 Transglycosylase 77 264 4.7E-57 T 09-03-2017 IPR001264 Glycosyl transferase, family 51 ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 Gene3D G3DSA:1.10.3810.10 78 267 1.2E-67 T 09-03-2017 ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 Gene3D G3DSA:3.40.710.10 268 736 3.3E-78 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS01715 a5c40fb2955104ced753b80a54870b6b 772 SUPERFAMILY SSF53955 66 291 1.27E-67 T 09-03-2017 IPR023346 Lysozyme-like domain ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 SUPERFAMILY SSF52467 155 342 1.06E-30 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 SUPERFAMILY SSF52518 360 534 1.39E-53 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 322 4.5E-19 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Gene3D G3DSA:3.40.50.970 378 535 4.6E-53 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Gene3D G3DSA:3.40.50.1220 181 377 3.9E-27 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 SUPERFAMILY SSF52518 3 179 1.14E-43 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 166 2.2E-43 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 7.9E-39 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS15475 9657a0346ef15dea31fc0f1350fcf879 540 Gene3D G3DSA:3.40.50.970 4 175 3.9E-50 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS19455 ebbf29f3ed69bc7759b5a3ee08413592 1197 Gene3D G3DSA:3.40.50.300 248 283 7.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19455 ebbf29f3ed69bc7759b5a3ee08413592 1197 Gene3D G3DSA:3.40.50.300 343 457 7.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19455 ebbf29f3ed69bc7759b5a3ee08413592 1197 SUPERFAMILY SSF52540 345 456 4.85E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19455 ebbf29f3ed69bc7759b5a3ee08413592 1197 SUPERFAMILY SSF52540 242 283 4.85E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00355 d1471cdfe6ef7f1d0e596cbd60495a5a 467 SUPERFAMILY SSF103473 30 457 8.63E-34 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00355 d1471cdfe6ef7f1d0e596cbd60495a5a 467 Pfam PF11700 Vacuole effluxer Atg22 like 161 419 2.8E-24 T 09-03-2017 IPR024671 Autophagy-related protein 22-like ARZXY2_RS00355 d1471cdfe6ef7f1d0e596cbd60495a5a 467 Gene3D G3DSA:1.20.1250.20 258 458 1.8E-13 T 09-03-2017 ARZXY2_RS00355 d1471cdfe6ef7f1d0e596cbd60495a5a 467 Gene3D G3DSA:1.20.1250.20 46 229 3.9E-9 T 09-03-2017 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 Pfam PF06445 GyrI-like small molecule binding domain 124 281 6.3E-15 T 09-03-2017 IPR029442 GyrI-like small molecule binding domain ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 Pfam PF12833 Helix-turn-helix domain 25 101 4.9E-18 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 96 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 SMART SM00342 18 100 5.7E-23 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 SUPERFAMILY SSF46689 54 104 1.37E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 SUPERFAMILY SSF55136 124 283 2.49E-15 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 Gene3D G3DSA:1.10.10.60 5 54 2.2E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 SMART SM00871 124 282 4.5E-20 T 09-03-2017 IPR010499 Bacterial transcription activator, effector binding ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 Gene3D G3DSA:3.20.80.10 112 281 1.4E-17 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 69 84 5.1E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 84 100 5.1E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 SUPERFAMILY SSF46689 4 52 2.66E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19880 a2d03fc1d30826bb7c94728bbc25149c 288 Gene3D G3DSA:1.10.10.60 55 111 1.7E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 Gene3D G3DSA:3.90.1150.10 286 428 1.3E-47 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 Gene3D G3DSA:3.40.640.10 38 285 5.3E-105 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 PIRSF PIRSF000412 3 432 6.1E-159 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 223 239 - T 09-03-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 SUPERFAMILY SSF53383 5 428 6.55E-172 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 Pfam PF00464 Serine hydroxymethyltransferase 9 391 5.3E-165 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS20365 906834801dd3a28d903d9e7bf6fa3d6f 449 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 8 427 50.767 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS01270 7a9ab9496b42606b333c6b4b9162a018 437 SUPERFAMILY SSF53850 73 430 1.59E-73 T 09-03-2017 ARZXY2_RS01270 7a9ab9496b42606b333c6b4b9162a018 437 Gene3D G3DSA:3.40.190.10 189 371 4.9E-42 T 09-03-2017 ARZXY2_RS01270 7a9ab9496b42606b333c6b4b9162a018 437 Pfam PF01547 Bacterial extracellular solute-binding protein 71 351 1.4E-29 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS01270 7a9ab9496b42606b333c6b4b9162a018 437 Gene3D G3DSA:3.40.190.10 61 188 1.6E-14 T 09-03-2017 ARZXY2_RS11400 728f279c6fd6b29a872e3b66fb928a9e 144 SMART SM00530 42 97 2.1E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS11400 728f279c6fd6b29a872e3b66fb928a9e 144 Gene3D G3DSA:1.10.260.40 39 107 3.1E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11400 728f279c6fd6b29a872e3b66fb928a9e 144 SUPERFAMILY SSF47413 32 101 9.29E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS11400 728f279c6fd6b29a872e3b66fb928a9e 144 Pfam PF13560 Helix-turn-helix domain 38 95 7.9E-11 T 09-03-2017 ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 SMART SM00421 799 855 5.0E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 SUPERFAMILY SSF46894 796 854 2.35E-13 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 SUPERFAMILY SSF52540 15 207 1.21E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 Pfam PF00196 Bacterial regulatory proteins, luxR family 800 853 6.9E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 Gene3D G3DSA:1.10.10.10 800 854 2.8E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13480 f4f16344e9cb392cc460ac214dd39e9c 862 Gene3D G3DSA:3.40.50.300 24 125 1.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 Gene3D G3DSA:3.40.309.10 262 444 2.5E-67 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 483 5.7E-198 T 09-03-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 Pfam PF00171 Aldehyde dehydrogenase family 18 479 5.4E-144 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 Gene3D G3DSA:3.40.605.10 5 261 2.0E-88 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16355 64d7c4dd7dde960008c6e93701b67587 499 SUPERFAMILY SSF53720 2 483 4.97E-155 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 SUPERFAMILY SSF82866 501 699 3.53E-29 T 09-03-2017 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 Pfam PF03176 MMPL family 477 704 7.1E-49 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 Pfam PF03176 MMPL family 51 373 6.8E-63 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 SUPERFAMILY SSF82866 113 334 4.05E-33 T 09-03-2017 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 Gene3D G3DSA:1.20.1640.10 126 335 4.9E-33 T 09-03-2017 ARZXY2_RS00565 ebac719705cfad08015cdc0016545caa 723 Gene3D G3DSA:1.20.1640.10 494 701 5.1E-24 T 09-03-2017 ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.2E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.2E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.2E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 Gene3D G3DSA:3.40.50.720 8 257 7.0E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 1.4E-34 T 09-03-2017 ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS12625 6334794715556bfc459760863a7bb3a2 258 SUPERFAMILY SSF51735 8 257 7.6E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 Pfam PF00119 ATP synthase A chain 41 257 5.7E-47 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 SUPERFAMILY SSF81336 90 257 1.96E-36 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 PRINTS PR00123 ATP synthase A subunit signature 244 259 2.2E-18 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 PRINTS PR00123 ATP synthase A subunit signature 183 205 2.2E-18 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 PRINTS PR00123 ATP synthase A subunit signature 99 115 2.2E-18 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 Hamap MF_01393 ATP synthase subunit a [atpB]. 20 264 13.922 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 37 260 6.0E-43 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS05230 f2a7b9864e5e737abf13c396434ba40e 266 Gene3D G3DSA:1.20.120.220 91 262 1.6E-37 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 ARZXY2_RS07135 eb05ed80996f813185f1337d47386f32 497 Gene3D G3DSA:3.40.605.10 20 279 1.5E-58 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07135 eb05ed80996f813185f1337d47386f32 497 SUPERFAMILY SSF53720 16 492 1.28E-109 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07135 eb05ed80996f813185f1337d47386f32 497 Gene3D G3DSA:3.40.309.10 280 453 7.1E-46 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS07135 eb05ed80996f813185f1337d47386f32 497 Pfam PF00171 Aldehyde dehydrogenase family 37 484 9.0E-103 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS20065 4dde6210402a350b8e76edb231f59631 282 Pfam PF13714 Phosphoenolpyruvate phosphomutase 14 253 3.1E-72 T 09-03-2017 ARZXY2_RS20065 4dde6210402a350b8e76edb231f59631 282 Gene3D G3DSA:3.20.20.60 9 234 7.6E-60 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS20065 4dde6210402a350b8e76edb231f59631 282 SUPERFAMILY SSF51621 7 262 1.48E-58 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS12735 25eb89e60cbbe47e3a32cacc63efd51e 151 SUPERFAMILY SSF82649 2 147 6.8E-38 T 09-03-2017 ARZXY2_RS12735 25eb89e60cbbe47e3a32cacc63efd51e 151 Pfam PF01592 NifU-like N terminal domain 7 133 2.6E-19 T 09-03-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 ARZXY2_RS12735 25eb89e60cbbe47e3a32cacc63efd51e 151 Gene3D G3DSA:3.90.1010.10 5 149 7.3E-39 T 09-03-2017 ARZXY2_RS12735 25eb89e60cbbe47e3a32cacc63efd51e 151 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 145 1.0E-38 T 09-03-2017 ARZXY2_RS04680 d6e5320bb9f70ca7fec1ff3f6bb1c1c7 543 SUPERFAMILY SSF55486 59 380 7.87E-23 T 09-03-2017 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 SUPERFAMILY SSF51971 344 373 6.47E-45 T 09-03-2017 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 SUPERFAMILY SSF51971 4 273 6.47E-45 T 09-03-2017 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 Gene3D G3DSA:3.40.50.720 3 82 7.1E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 Gene3D G3DSA:3.40.50.720 334 380 7.1E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 Gene3D G3DSA:3.40.50.720 186 264 7.1E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 Pfam PF03275 UDP-galactopyranose mutase 151 359 1.2E-82 T 09-03-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 SUPERFAMILY SSF54373 255 326 2.94E-23 T 09-03-2017 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 76 5.2E-17 T 09-03-2017 ARZXY2_RS04855 b8f81b2135db839339d6880f36c302d4 394 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 377 3.8E-100 T 09-03-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 ARZXY2_RS01755 2db407ed671a50a59cb34ee21c582054 306 Gene3D G3DSA:1.10.3720.10 13 292 2.4E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01755 2db407ed671a50a59cb34ee21c582054 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 291 1.5E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01755 2db407ed671a50a59cb34ee21c582054 306 SUPERFAMILY SSF161098 20 306 1.03E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 TIGRFAM TIGR00498 lexA: repressor LexA 22 247 5.1E-68 T 09-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 SUPERFAMILY SSF51306 128 246 1.03E-35 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 Pfam PF01726 LexA DNA binding domain 22 85 3.3E-23 T 09-03-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 Gene3D G3DSA:2.10.109.10 129 247 3.1E-43 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 164 174 5.0E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 203 215 5.0E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 175 186 5.0E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 SUPERFAMILY SSF46785 23 89 6.4E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 Hamap MF_00015 LexA repressor [lexA]. 23 248 32.137 T 09-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 Gene3D G3DSA:1.10.10.10 22 89 7.3E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11345 dfb24e532fc51200bba4613c6663680d 248 Pfam PF00717 Peptidase S24-like 167 230 2.3E-14 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS02515 22f5881d3bfa130e0a83379dc35beeba 270 Pfam PF00535 Glycosyl transferase family 2 8 141 1.1E-17 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS02515 22f5881d3bfa130e0a83379dc35beeba 270 Gene3D G3DSA:3.90.550.10 8 193 9.4E-34 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02515 22f5881d3bfa130e0a83379dc35beeba 270 SUPERFAMILY SSF53448 5 194 5.34E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS09390 49332fa2c3ec99037bc66b306e59b9a3 235 SUPERFAMILY SSF51621 1 231 5.34E-74 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS09390 49332fa2c3ec99037bc66b306e59b9a3 235 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 1 223 2.8E-50 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS09390 49332fa2c3ec99037bc66b306e59b9a3 235 Gene3D G3DSA:3.20.20.60 1 227 2.3E-69 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 SUPERFAMILY SSF54862 3 87 6.05E-22 T 09-03-2017 ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.0E-18 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.0E-18 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.0E-18 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain ARZXY2_RS04250 f347b26fb82196e0707b6539697644a9 108 Gene3D G3DSA:3.30.70.20 3 74 4.4E-19 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 185 244 1.0E-17 T 09-03-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 SUPERFAMILY SSF81301 6 152 1.42E-39 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 12 471 4.0E-221 T 09-03-2017 IPR014065 tRNA adenylyltransferase ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 SMART SM00471 254 415 7.0E-6 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Gene3D G3DSA:1.10.3090.10 416 438 1.4E-52 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Gene3D G3DSA:1.10.3090.10 155 348 1.4E-52 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 TIGRFAM TIGR00277 HDIG: HDIG domain 255 332 4.4E-13 T 09-03-2017 IPR006675 HDIG domain ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 SUPERFAMILY SSF81891 156 472 2.75E-64 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Gene3D G3DSA:3.30.460.10 12 152 4.1E-43 T 09-03-2017 ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Pfam PF01966 HD domain 258 352 2.0E-12 T 09-03-2017 IPR006674 HD domain ARZXY2_RS18635 ee84a4c50ea569b0f7780ed0c5385a5f 488 Pfam PF01743 Poly A polymerase head domain 34 153 1.5E-31 T 09-03-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 ARZXY2_RS00135 c6697cd16d9edba27d07479d32174c79 98 SMART SM00450 2 96 3.9E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00135 c6697cd16d9edba27d07479d32174c79 98 Pfam PF00581 Rhodanese-like domain 7 92 9.4E-14 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00135 c6697cd16d9edba27d07479d32174c79 98 Gene3D G3DSA:3.40.250.10 2 97 2.1E-27 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00135 c6697cd16d9edba27d07479d32174c79 98 SUPERFAMILY SSF52821 3 97 1.23E-29 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02085 34705d49e803ed24ea335b336d82d0de 223 Gene3D G3DSA:3.40.50.1110 2 209 1.1E-61 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS02085 34705d49e803ed24ea335b336d82d0de 223 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 197 1.8E-19 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS02085 34705d49e803ed24ea335b336d82d0de 223 SUPERFAMILY SSF52266 1 210 4.89E-47 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS13415 70a77fa906c4623351a1b2e4eac3fb4b 233 SUPERFAMILY SSF52980 124 229 2.09E-6 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS14045 29c64187f52ff507147149fc7f98b2f7 331 Gene3D G3DSA:3.40.50.2300 45 165 3.7E-27 T 09-03-2017 ARZXY2_RS14045 29c64187f52ff507147149fc7f98b2f7 331 Pfam PF13407 Periplasmic binding protein domain 58 297 2.9E-36 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS14045 29c64187f52ff507147149fc7f98b2f7 331 SUPERFAMILY SSF53822 48 323 1.02E-47 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS14045 29c64187f52ff507147149fc7f98b2f7 331 Gene3D G3DSA:3.40.50.2300 166 298 3.3E-15 T 09-03-2017 ARZXY2_RS00110 2b2de2a10abde984290a78aa854afb0f 138 PIRSF PIRSF021774 1 135 3.8E-43 T 09-03-2017 IPR016796 Uncharacterised conserved protein UCP021774 ARZXY2_RS00110 2b2de2a10abde984290a78aa854afb0f 138 Gene3D G3DSA:3.30.310.70 3 132 8.8E-43 T 09-03-2017 IPR005180 Domain of unknown function DUF302 ARZXY2_RS00110 2b2de2a10abde984290a78aa854afb0f 138 Pfam PF03625 Domain of unknown function DUF302 35 103 2.3E-23 T 09-03-2017 IPR005180 Domain of unknown function DUF302 ARZXY2_RS00110 2b2de2a10abde984290a78aa854afb0f 138 SUPERFAMILY SSF103247 2 133 1.7E-30 T 09-03-2017 IPR005180 Domain of unknown function DUF302 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 Pfam PF00664 ABC transporter transmembrane region 53 364 1.5E-63 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 SMART SM00382 434 626 3.6E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 Gene3D G3DSA:3.40.50.300 409 637 3.5E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 ProSitePatterns PS00211 ABC transporters family signature. 546 560 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 SUPERFAMILY SSF52540 405 645 1.67E-87 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 Gene3D G3DSA:1.20.1560.10 39 88 1.6E-90 T 09-03-2017 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 Gene3D G3DSA:1.20.1560.10 122 397 1.6E-90 T 09-03-2017 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 Pfam PF00005 ABC transporter 427 574 2.4E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 SUPERFAMILY SSF90123 124 397 1.31E-87 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01430 3955c370a9739bd33753502f6a94152b 652 SUPERFAMILY SSF90123 39 83 1.31E-87 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 Gene3D G3DSA:3.40.50.920 199 320 1.9E-43 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 SUPERFAMILY SSF52518 3 183 4.91E-62 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 Gene3D G3DSA:3.40.50.970 2 187 1.1E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 177 4.0E-41 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 SMART SM00861 4 179 1.2E-60 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 Pfam PF02780 Transketolase, C-terminal domain 196 316 1.4E-39 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS20015 a76b7048bae238cbd43cb7fb48239d90 326 SUPERFAMILY SSF52922 196 323 2.22E-38 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 Gene3D G3DSA:3.40.50.620 37 341 1.4E-70 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 37 348 6.9E-79 T 09-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 257 278 3.5E-17 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.5E-17 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.5E-17 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 226 244 3.5E-17 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 427 4.9E-201 T 09-03-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 SUPERFAMILY SSF52374 34 349 1.9E-65 T 09-03-2017 ARZXY2_RS08690 2a9b926a16eaee177724c3ced767ea52 427 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 427 53.095 T 09-03-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 Pfam PF00582 Universal stress protein family 5 142 8.0E-21 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 Pfam PF00582 Universal stress protein family 151 280 5.4E-14 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 PRINTS PR01438 Universal stress protein signature 102 114 2.7E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 PRINTS PR01438 Universal stress protein signature 4 22 2.7E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 PRINTS PR01438 Universal stress protein signature 120 142 2.7E-13 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 Gene3D G3DSA:3.40.50.620 3 142 1.8E-29 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 Gene3D G3DSA:3.40.50.620 148 279 3.3E-22 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 SUPERFAMILY SSF52402 5 142 4.86E-28 T 09-03-2017 ARZXY2_RS16325 b7c06491dcc6c4a649bcc2f9016fd9fd 284 SUPERFAMILY SSF52402 150 282 2.68E-19 T 09-03-2017 ARZXY2_RS20040 813d570825cd02c66ac27290850ffca2 318 PIRSF PIRSF016660 1 311 2.4E-105 T 09-03-2017 IPR008526 Inner membrane protein YedI ARZXY2_RS20040 813d570825cd02c66ac27290850ffca2 318 Pfam PF05661 Protein of unknown function (DUF808) 4 299 4.9E-119 T 09-03-2017 IPR008526 Inner membrane protein YedI ARZXY2_RS00550 5cb9820d50ea2826a1d43134e35f1e30 119 Pfam PF03795 YCII-related domain 1 101 3.2E-8 T 09-03-2017 IPR005545 YCII-related ARZXY2_RS00550 5cb9820d50ea2826a1d43134e35f1e30 119 SUPERFAMILY SSF54909 1 100 5.2E-20 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS00550 5cb9820d50ea2826a1d43134e35f1e30 119 Gene3D G3DSA:3.30.70.1060 1 112 7.0E-29 T 09-03-2017 ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 Pfam PF04229 GrpB protein 215 382 4.6E-43 T 09-03-2017 IPR007344 GrpB/Dephospho-CoA kinase ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 Pfam PF01121 Dephospho-CoA kinase 4 179 2.0E-58 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 SUPERFAMILY SSF81301 215 382 5.56E-40 T 09-03-2017 ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 Gene3D G3DSA:3.30.460.10 215 383 2.0E-48 T 09-03-2017 ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 26.097 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 SUPERFAMILY SSF52540 3 194 6.68E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 Gene3D G3DSA:3.40.50.300 3 192 6.7E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09165 18c8e71d783eca13d796b9fe622a4863 403 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 186 9.1E-45 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 ARZXY2_RS20225 63594b7a02c73191006265682bcbebce 485 PIRSF PIRSF006060 5 442 6.0E-67 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS20225 63594b7a02c73191006265682bcbebce 485 Pfam PF00324 Amino acid permease 29 433 1.3E-106 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS07890 5c8896a30c255b485a51cf3b3651b468 248 SUPERFAMILY SSF143081 7 244 7.06E-57 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) ARZXY2_RS07890 5c8896a30c255b485a51cf3b3651b468 248 Pfam PF02586 SOS response associated peptidase (SRAP) 6 233 1.2E-57 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) ARZXY2_RS07890 5c8896a30c255b485a51cf3b3651b468 248 Gene3D G3DSA:3.90.1680.10 7 244 3.5E-63 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) ARZXY2_RS03935 101523289a4aa502e3eba7314c02e97d 299 Pfam PF02104 SURF1 family 20 233 7.2E-18 T 09-03-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.0E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Gene3D G3DSA:2.40.33.10 73 166 1.4E-28 T 09-03-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Gene3D G3DSA:3.20.20.60 167 322 3.2E-99 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Gene3D G3DSA:3.20.20.60 2 72 3.2E-99 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 SUPERFAMILY SSF51621 1 74 1.08E-96 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 SUPERFAMILY SSF51621 154 335 1.08E-96 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Pfam PF02887 Pyruvate kinase, alpha/beta domain 353 465 1.6E-30 T 09-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 467 5.1E-166 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 SUPERFAMILY SSF52935 320 468 7.59E-41 T 09-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Gene3D G3DSA:3.40.1380.20 323 467 1.3E-42 T 09-03-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 09-03-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 Pfam PF00224 Pyruvate kinase, barrel domain 1 334 2.7E-121 T 09-03-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 ARZXY2_RS10240 9628b3607b5e66b2e16bc9e18b91e9d5 496 SUPERFAMILY SSF50800 70 164 3.14E-26 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain ARZXY2_RS13995 e4c190f8af4273070ac839d4c13585e9 505 Pfam PF00474 Sodium:solute symporter family 35 429 1.4E-29 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS12835 db1009511aeccb1d96f0fb850020622e 493 SUPERFAMILY SSF53720 14 487 9.82E-162 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12835 db1009511aeccb1d96f0fb850020622e 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12835 db1009511aeccb1d96f0fb850020622e 493 Pfam PF00171 Aldehyde dehydrogenase family 25 485 3.0E-164 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12835 db1009511aeccb1d96f0fb850020622e 493 Gene3D G3DSA:3.40.309.10 276 460 7.3E-66 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS12835 db1009511aeccb1d96f0fb850020622e 493 Gene3D G3DSA:3.40.605.10 16 275 3.0E-95 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07090 dced6cf0ba7485eb6336f0b884f9659d 343 Pfam PF04860 Phage portal protein 60 327 1.0E-13 T 09-03-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein ARZXY2_RS14020 1a0f16e3b1b1033df32d1a5875ab98ff 379 SUPERFAMILY SSF102405 256 374 6.72E-26 T 09-03-2017 ARZXY2_RS14020 1a0f16e3b1b1033df32d1a5875ab98ff 379 SUPERFAMILY SSF102405 156 215 6.72E-26 T 09-03-2017 ARZXY2_RS14020 1a0f16e3b1b1033df32d1a5875ab98ff 379 Gene3D G3DSA:3.40.50.450 163 212 3.0E-37 T 09-03-2017 ARZXY2_RS14020 1a0f16e3b1b1033df32d1a5875ab98ff 379 Gene3D G3DSA:3.40.50.450 253 375 3.0E-37 T 09-03-2017 ARZXY2_RS14020 1a0f16e3b1b1033df32d1a5875ab98ff 379 Pfam PF03641 Possible lysine decarboxylase 259 373 1.9E-4 T 09-03-2017 IPR031100 LOG family ARZXY2_RS11410 1bd416bbc11d025823bf353013489ede 200 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 88 4.1E-15 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS11410 1bd416bbc11d025823bf353013489ede 200 PIRSF PIRSF000847 14 200 5.0E-44 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 ARZXY2_RS11410 1bd416bbc11d025823bf353013489ede 200 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 66 88 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS11410 1bd416bbc11d025823bf353013489ede 200 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 18 192 6.7E-37 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 ARZXY2_RS13940 60beb12186538a267632a1328f8110e2 741 Gene3D G3DSA:3.40.50.300 467 642 5.8E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13940 60beb12186538a267632a1328f8110e2 741 Pfam PF07728 AAA domain (dynein-related subfamily) 481 635 3.3E-19 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 ARZXY2_RS13940 60beb12186538a267632a1328f8110e2 741 SMART SM00382 477 645 2.8E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13940 60beb12186538a267632a1328f8110e2 741 SUPERFAMILY SSF52540 469 684 6.89E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02635 1c75513150b903f7b5107a676d35894f 843 SUPERFAMILY SSF53756 399 688 9.31E-5 T 09-03-2017 ARZXY2_RS02635 1c75513150b903f7b5107a676d35894f 843 Pfam PF13524 Glycosyl transferases group 1 249 323 1.3E-5 T 09-03-2017 ARZXY2_RS14555 9aa2f3ce2f982e869a3273a71eb708b0 113 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 8 111 2.1E-19 T 09-03-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 ARZXY2_RS14555 9aa2f3ce2f982e869a3273a71eb708b0 113 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 09-03-2017 IPR019776 Flagellar basal body rod protein, conserved site ARZXY2_RS14555 9aa2f3ce2f982e869a3273a71eb708b0 113 Pfam PF00460 Flagella basal body rod protein 11 37 1.2E-8 T 09-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 Pfam PF02780 Transketolase, C-terminal domain 178 299 3.9E-23 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 SMART SM00861 2 168 7.2E-47 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 Pfam PF02779 Transketolase, pyrimidine binding domain 5 165 2.6E-32 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 Gene3D G3DSA:3.40.50.970 3 178 2.1E-52 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 SUPERFAMILY SSF52518 3 166 4.21E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 SUPERFAMILY SSF52922 169 307 8.11E-27 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS00865 11a6b0f83ba7a8677206d68d87397413 310 Gene3D G3DSA:3.40.50.920 179 307 2.0E-27 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS15985 ab1b47915a5d9fcc9dd8906aa659a90a 473 SUPERFAMILY SSF103473 33 455 1.07E-29 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15985 ab1b47915a5d9fcc9dd8906aa659a90a 473 Gene3D G3DSA:1.20.1250.20 38 230 1.3E-14 T 09-03-2017 ARZXY2_RS15985 ab1b47915a5d9fcc9dd8906aa659a90a 473 Gene3D G3DSA:1.20.1250.20 255 458 1.3E-7 T 09-03-2017 ARZXY2_RS15985 ab1b47915a5d9fcc9dd8906aa659a90a 473 Pfam PF07690 Major Facilitator Superfamily 42 391 7.9E-14 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS12375 57c75e62726ca7f326a41744f5da1bd6 130 SUPERFAMILY SSF55298 1 128 1.08E-27 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS12375 57c75e62726ca7f326a41744f5da1bd6 130 Gene3D G3DSA:3.30.1330.40 2 128 3.0E-33 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS12375 57c75e62726ca7f326a41744f5da1bd6 130 Pfam PF01042 Endoribonuclease L-PSP 16 127 1.9E-20 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family ARZXY2_RS05790 dc88e2bbf2a843b0bb94f841c15eeb5e 331 Pfam PF02734 DAK2 domain 26 200 1.6E-29 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS05790 dc88e2bbf2a843b0bb94f841c15eeb5e 331 SMART SM01120 26 202 4.3E-41 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS05790 dc88e2bbf2a843b0bb94f841c15eeb5e 331 SUPERFAMILY SSF101473 2 203 7.98E-32 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS05790 dc88e2bbf2a843b0bb94f841c15eeb5e 331 Pfam PF13684 Dihydroxyacetone kinase family 238 320 6.6E-8 T 09-03-2017 IPR033470 Uncharacterised protein, DhaK domain ARZXY2_RS18510 9ace7c206219975599f8498f44fbe088 292 SUPERFAMILY SSF53448 16 249 8.13E-47 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS18510 9ace7c206219975599f8498f44fbe088 292 Gene3D G3DSA:3.90.550.10 18 216 8.0E-41 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS18510 9ace7c206219975599f8498f44fbe088 292 Pfam PF00535 Glycosyl transferase family 2 21 183 1.3E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 SMART SM00346 22 112 4.8E-17 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 Gene3D G3DSA:3.30.450.40 93 268 6.5E-36 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 Gene3D G3DSA:1.10.10.10 11 83 1.0E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 SUPERFAMILY SSF46785 25 91 4.94E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 Pfam PF09339 IclR helix-turn-helix domain 25 74 5.0E-14 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 SUPERFAMILY SSF55781 94 267 6.02E-34 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS20385 91f7aef5c00d7d87b88888b976ffad17 271 Pfam PF01614 Bacterial transcriptional regulator 152 262 6.4E-12 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal ARZXY2_RS08655 09e3d88e81cc76826fd3fe7d394400cd 67 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 36 67 7.3E-23 T 09-03-2017 IPR008515 Ubiquitin-like, Pup ARZXY2_RS08655 09e3d88e81cc76826fd3fe7d394400cd 67 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 67 17.394 T 09-03-2017 IPR008515 Ubiquitin-like, Pup ARZXY2_RS08655 09e3d88e81cc76826fd3fe7d394400cd 67 Pfam PF05639 Pup-like protein 2 67 3.0E-24 T 09-03-2017 IPR008515 Ubiquitin-like, Pup ARZXY2_RS03005 bdb77fe2a8d578398226a189e01997f7 423 Pfam PF05977 Transmembrane secretion effector 8 401 3.6E-35 T 09-03-2017 IPR010290 Transmembrane secretion effector ARZXY2_RS03005 bdb77fe2a8d578398226a189e01997f7 423 SUPERFAMILY SSF103473 16 411 1.7E-33 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03005 bdb77fe2a8d578398226a189e01997f7 423 Gene3D G3DSA:1.20.1250.20 23 202 5.5E-16 T 09-03-2017 ARZXY2_RS03005 bdb77fe2a8d578398226a189e01997f7 423 Gene3D G3DSA:1.20.1250.20 242 411 2.8E-7 T 09-03-2017 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 Pfam PF01266 FAD dependent oxidoreductase 13 398 2.9E-67 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 Gene3D G3DSA:3.50.50.60 10 83 6.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 Gene3D G3DSA:3.50.50.60 145 223 6.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 SUPERFAMILY SSF51905 11 224 2.89E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 SUPERFAMILY SSF51905 359 402 2.89E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 Gene3D G3DSA:3.30.9.10 94 144 1.3E-6 T 09-03-2017 ARZXY2_RS14670 8b36336d8a86afc6899989ac68366740 404 Gene3D G3DSA:3.30.9.10 225 353 1.3E-6 T 09-03-2017 ARZXY2_RS14220 9b8f55971cd933caf092c0edd7680371 166 Pfam PF14279 HNH endonuclease 82 129 5.5E-14 T 09-03-2017 IPR029471 HNH endonuclease 5 ARZXY2_RS14220 9b8f55971cd933caf092c0edd7680371 166 SMART SM00507 69 118 2.3E-14 T 09-03-2017 IPR003615 HNH nuclease ARZXY2_RS12605 9669a44586b480ecd749f4b31815e36c 561 Pfam PF01740 STAS domain 430 529 8.0E-15 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS12605 9669a44586b480ecd749f4b31815e36c 561 Gene3D G3DSA:3.30.750.24 433 537 8.5E-14 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS12605 9669a44586b480ecd749f4b31815e36c 561 Pfam PF00916 Sulfate permease family 22 386 7.3E-67 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS12605 9669a44586b480ecd749f4b31815e36c 561 SUPERFAMILY SSF52091 433 538 4.12E-16 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 Gene3D G3DSA:3.20.20.100 3 268 2.9E-94 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 224 239 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 SUPERFAMILY SSF51430 4 261 2.1E-81 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PRINTS PR00069 Aldo-keto reductase signature 120 137 4.2E-41 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PRINTS PR00069 Aldo-keto reductase signature 88 106 4.2E-41 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PRINTS PR00069 Aldo-keto reductase signature 154 183 4.2E-41 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PRINTS PR00069 Aldo-keto reductase signature 191 215 4.2E-41 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PRINTS PR00069 Aldo-keto reductase signature 34 58 4.2E-41 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 Pfam PF00248 Aldo/keto reductase family 21 256 1.3E-43 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS17515 9c8edd858b8a1c993076c693b9dfe1da 273 PIRSF PIRSF000097 1 270 2.7E-72 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 SUPERFAMILY SSF46785 19 166 1.82E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 SMART SM00347 51 154 1.1E-22 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 9.8E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 9.8E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 9.8E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 Gene3D G3DSA:1.10.10.10 13 166 2.9E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09530 d1cf5d8a1971e3e916fb66a0ddefaeaf 185 Pfam PF12802 MarR family 56 117 4.9E-13 T 09-03-2017 ARZXY2_RS17585 cf794ee7fae86641fcfb451fca1f8b6e 117 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.012 T 09-03-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17585 cf794ee7fae86641fcfb451fca1f8b6e 117 SUPERFAMILY SSF51278 1 104 6.67E-46 T 09-03-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17585 cf794ee7fae86641fcfb451fca1f8b6e 117 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 1.3E-43 T 09-03-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17585 cf794ee7fae86641fcfb451fca1f8b6e 117 Pfam PF00699 Urease beta subunit 3 99 5.3E-43 T 09-03-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS17585 cf794ee7fae86641fcfb451fca1f8b6e 117 Gene3D G3DSA:2.10.150.10 1 103 2.6E-48 T 09-03-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 ARZXY2_RS01720 9753dbac7b1a41f146a9280f93437786 178 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 21 176 1.7E-31 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS01720 9753dbac7b1a41f146a9280f93437786 178 Gene3D G3DSA:3.30.1330.40 18 176 5.4E-68 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS01720 9753dbac7b1a41f146a9280f93437786 178 SUPERFAMILY SSF55298 19 176 3.14E-53 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 SUPERFAMILY SSF52540 284 351 3.18E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 SUPERFAMILY SSF52540 809 871 3.18E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 SUPERFAMILY SSF52540 905 1097 3.18E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 Gene3D G3DSA:3.40.50.300 969 1097 5.0E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 Gene3D G3DSA:3.40.50.300 836 936 5.4E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03950 9f40fa958f8640c3ef5ac2e8c1f5f278 1425 Gene3D G3DSA:3.40.50.300 272 394 5.4E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 SMART SM00895 89 214 1.9E-12 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 SUPERFAMILY SSF46785 13 105 8.37E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 SUPERFAMILY SSF48008 87 222 4.97E-20 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 Gene3D G3DSA:1.10.10.10 8 78 1.9E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 SMART SM00345 21 79 1.2E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 1.1E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 Gene3D G3DSA:1.20.120.530 85 223 2.1E-21 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS16445 4d77ad4a631d2f2ef637482cacaec014 226 Pfam PF07729 FCD domain 91 213 7.2E-18 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 TIGRFAM TIGR00077 lspA: signal peptidase II 27 167 3.2E-27 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 23 175 15.278 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 Pfam PF01252 Signal peptidase (SPase) II 32 168 1.3E-31 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 70 78 1.2E-15 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 112 127 1.2E-15 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 150 166 1.2E-15 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS10800 3d7093dfa97f0aa48eb6bca34abe2f5e 196 ProSitePatterns PS00855 Signal peptidases II signature. 115 127 - T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 ARZXY2_RS12880 058939b770157f4e4ac97e26970be164 62 Gene3D G3DSA:2.20.25.10 11 55 1.4E-8 T 09-03-2017 ARZXY2_RS12880 058939b770157f4e4ac97e26970be164 62 SUPERFAMILY SSF158997 5 58 9.68E-9 T 09-03-2017 ARZXY2_RS06310 62a4f303c650f8e4d7c5362edd3ad7e3 240 SUPERFAMILY SSF109604 26 201 7.33E-19 T 09-03-2017 ARZXY2_RS06310 62a4f303c650f8e4d7c5362edd3ad7e3 240 SMART SM00471 63 179 2.0E-6 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS06310 62a4f303c650f8e4d7c5362edd3ad7e3 240 Pfam PF13328 HD domain 64 111 5.9E-7 T 09-03-2017 IPR003607 HD/PDEase domain ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 SUPERFAMILY SSF53474 467 718 1.38E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 SUPERFAMILY SSF50993 15 459 1.18E-85 T 09-03-2017 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 557 587 - T 09-03-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 18 439 1.4E-83 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 Gene3D G3DSA:2.130.10.120 86 455 9.8E-95 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 657 679 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 550 569 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 522 546 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 639 654 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 514 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 580 600 5.2E-48 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 Pfam PF00326 Prolyl oligopeptidase family 516 728 5.9E-63 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ARZXY2_RS02360 8576142fdab0b76a4559a34b0a29ea48 739 Gene3D G3DSA:3.40.50.1820 471 712 3.7E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 Gene3D G3DSA:3.40.50.300 865 1067 3.5E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 Gene3D G3DSA:3.40.50.300 393 471 3.5E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 402 686 1.9E-6 T 09-03-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 SUPERFAMILY SSF52540 867 1065 1.59E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 SUPERFAMILY SSF52540 403 560 1.59E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06795 14e15c6c9f159023fa8870b60ef40261 1364 Pfam PF12696 TraM recognition site of TraD and TraG 922 1048 6.1E-14 T 09-03-2017 IPR032689 TraD/TraG, TraM recognition site ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 8 462 5.3E-234 T 09-03-2017 IPR017817 Mycothione reductase MetaCyc: PWY-6421 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 SUPERFAMILY SSF51905 30 380 9.27E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 1.6E-26 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 4.0E-41 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 Gene3D G3DSA:3.50.50.60 9 150 1.4E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 325 1.4E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 Gene3D G3DSA:3.50.50.60 151 336 9.9E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 SUPERFAMILY SSF55424 346 459 1.89E-31 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 3.7E-18 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 3.7E-18 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.7E-18 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 3.7E-18 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 3.7E-18 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 PIRSF PIRSF000350 2 451 2.6E-75 T 09-03-2017 ARZXY2_RS20045 be4f49cb4b596aabc0dd04635b534df4 465 Gene3D G3DSA:3.30.390.30 339 461 5.8E-38 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS01510 76c817b44483f63f02d22d1af26ba163 195 Pfam PF09350 Domain of unknown function (DUF1992) 51 117 2.6E-13 T 09-03-2017 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain ARZXY2_RS03355 bf3858315341a7da828179158369e958 249 SUPERFAMILY SSF55729 97 243 3.36E-13 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03355 bf3858315341a7da828179158369e958 249 Gene3D G3DSA:3.40.630.30 180 241 3.3E-9 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03355 bf3858315341a7da828179158369e958 249 Pfam PF00583 Acetyltransferase (GNAT) family 178 238 3.5E-6 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS06935 97bdef6735ffca14126ec74016c3d66a 342 Pfam PF07676 WD40-like Beta Propeller Repeat 244 257 0.0044 T 09-03-2017 IPR011659 WD40-like Beta Propeller ARZXY2_RS06935 97bdef6735ffca14126ec74016c3d66a 342 SUPERFAMILY SSF82171 129 322 1.84E-12 T 09-03-2017 ARZXY2_RS06935 97bdef6735ffca14126ec74016c3d66a 342 Gene3D G3DSA:2.120.10.30 136 323 2.4E-13 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS05000 59c556834d2cb300abf2e317fa5da9dc 245 Pfam PF08241 Methyltransferase domain 45 132 7.0E-18 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 ARZXY2_RS05000 59c556834d2cb300abf2e317fa5da9dc 245 SUPERFAMILY SSF53335 11 204 7.19E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05000 59c556834d2cb300abf2e317fa5da9dc 245 Gene3D G3DSA:3.40.50.150 8 145 4.3E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS19810 21d8ba7316f7df1cf62886817d883b98 452 SUPERFAMILY SSF51126 5 339 6.29E-17 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor ARZXY2_RS19810 21d8ba7316f7df1cf62886817d883b98 452 Pfam PF05048 Periplasmic copper-binding protein (NosD) 159 304 8.3E-9 T 09-03-2017 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain ARZXY2_RS05270 8b6683cb5761ea899291fc0e7ef581e1 143 Pfam PF10739 Protein of unknown function (DUF2550) 16 135 9.9E-37 T 09-03-2017 IPR019675 Protein of unknown function DUF2550 ARZXY2_RS17510 0bf4f1f5bc12cc193013f3c49d3ac9a2 293 Pfam PF13560 Helix-turn-helix domain 6 86 4.1E-19 T 09-03-2017 ARZXY2_RS17510 0bf4f1f5bc12cc193013f3c49d3ac9a2 293 SUPERFAMILY SSF47413 32 82 1.44E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS17510 0bf4f1f5bc12cc193013f3c49d3ac9a2 293 Gene3D G3DSA:1.10.260.40 5 82 1.5E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS17510 0bf4f1f5bc12cc193013f3c49d3ac9a2 293 SMART SM00530 10 83 3.8E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS03975 38f2bf8895e1bbb4a313c526bc28bc0a 208 SUPERFAMILY SSF55729 8 188 8.66E-37 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03975 38f2bf8895e1bbb4a313c526bc28bc0a 208 Pfam PF13302 Acetyltransferase (GNAT) domain 16 164 3.5E-17 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS03975 38f2bf8895e1bbb4a313c526bc28bc0a 208 Gene3D G3DSA:3.40.630.30 5 194 4.0E-52 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 448 653 1.1E-20 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Gene3D G3DSA:3.40.50.300 424 707 1.7E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 SMART SM00357 339 411 5.2E-6 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 TIGRFAM TIGR00767 rho: transcription termination factor Rho 30 707 2.6E-190 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Pfam PF07497 Rho termination factor, RNA-binding domain 338 418 3.9E-28 T 09-03-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 SUPERFAMILY SSF50249 338 418 9.42E-16 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Hamap MF_01884 Transcription termination factor Rho [rho]. 330 709 195.239 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Gene3D G3DSA:2.40.50.140 29 70 5.2E-40 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Gene3D G3DSA:2.40.50.140 333 419 5.2E-40 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 SMART SM00382 460 645 2.1E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 SUPERFAMILY SSF52540 376 661 2.35E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 Pfam PF07498 Rho termination factor, N-terminal domain 31 63 6.1E-9 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 ARZXY2_RS05185 4fd88d4f75fab62d46cf29a533bb248a 719 SMART SM00959 30 69 4.4E-7 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 ARZXY2_RS09550 7ff7bbc34ec1af29ff67321dc9b55529 213 SUPERFAMILY SSF53474 15 171 2.23E-13 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09550 7ff7bbc34ec1af29ff67321dc9b55529 213 Gene3D G3DSA:3.40.50.1820 15 191 3.8E-12 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 218 6.9E-54 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 237 15.818 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 82 100 2.2E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 150 178 2.2E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 2.2E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 100 126 2.2E-34 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS08610 3d8117c39fd9a6cdb7dacc9da0edcbdf 264 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 223 5.2E-51 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 Gene3D G3DSA:3.40.50.720 1 154 5.6E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 Gene3D G3DSA:3.30.360.10 155 315 8.5E-58 T 09-03-2017 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 SUPERFAMILY SSF51735 3 175 3.36E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 318 3.2E-19 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 SMART SM00859 4 136 4.2E-44 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 136 2.8E-28 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 347 7.7E-116 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 341 38.967 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 09-03-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 ARZXY2_RS11230 589cd99b29f7efa98e440101a31d6557 347 SUPERFAMILY SSF55347 146 315 7.33E-48 T 09-03-2017 ARZXY2_RS02550 c9977e99497c28c9f73b1f9c4c8b344e 89 Pfam PF01610 Transposase 2 87 1.2E-16 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS04695 b34c72b4a2984a6046f71e81e7a20292 363 Gene3D G3DSA:1.10.3720.10 229 358 4.2E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04695 b34c72b4a2984a6046f71e81e7a20292 363 Gene3D G3DSA:1.10.3720.10 122 187 4.2E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04695 b34c72b4a2984a6046f71e81e7a20292 363 SUPERFAMILY SSF161098 226 350 1.03E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04695 b34c72b4a2984a6046f71e81e7a20292 363 SUPERFAMILY SSF161098 120 184 1.03E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04695 b34c72b4a2984a6046f71e81e7a20292 363 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 363 1.5E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13310 5733cc869f4405ba1e1bc384ab12de42 504 PIRSF PIRSF006060 27 497 4.0E-93 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS13310 5733cc869f4405ba1e1bc384ab12de42 504 Pfam PF13520 Amino acid permease 46 448 5.6E-58 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 SMART SM00382 36 223 1.1E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 PIRSF PIRSF039085 8 251 2.4E-111 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 Gene3D G3DSA:3.40.50.300 12 246 2.5E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 Pfam PF00005 ABC transporter 27 175 8.3E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02790 76461987d7e2f3fe5fe337a82677f2d8 260 SUPERFAMILY SSF52540 13 245 2.1E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00120 2edbb5f13ec2cb600e439525cd939f18 206 Pfam PF11127 Protein of unknown function (DUF2892) 121 179 1.2E-8 T 09-03-2017 IPR021309 Protein of unknown function DUF2892 ARZXY2_RS00120 2edbb5f13ec2cb600e439525cd939f18 206 Gene3D G3DSA:3.40.250.10 4 116 1.2E-26 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00120 2edbb5f13ec2cb600e439525cd939f18 206 SMART SM00450 14 111 1.8E-19 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00120 2edbb5f13ec2cb600e439525cd939f18 206 Pfam PF00581 Rhodanese-like domain 19 107 2.1E-12 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00120 2edbb5f13ec2cb600e439525cd939f18 206 SUPERFAMILY SSF52821 8 118 7.86E-30 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS02390 96b2493a1d6cbfa6eebafb8908375259 140 Pfam PF06243 Phenylacetic acid degradation B 51 136 3.2E-36 T 09-03-2017 IPR009359 Phenylacetic acid degradation B ARZXY2_RS02390 96b2493a1d6cbfa6eebafb8908375259 140 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 51 139 2.9E-37 T 09-03-2017 IPR009359 Phenylacetic acid degradation B ARZXY2_RS08375 a126c94e7f57155df8cda71d4767babd 129 Gene3D G3DSA:2.60.300.12 25 118 2.1E-28 T 09-03-2017 IPR000361 FeS cluster biogenesis ARZXY2_RS08375 a126c94e7f57155df8cda71d4767babd 129 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 111 128 - T 09-03-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site ARZXY2_RS08375 a126c94e7f57155df8cda71d4767babd 129 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 25 129 1.9E-34 T 09-03-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 ARZXY2_RS08375 a126c94e7f57155df8cda71d4767babd 129 SUPERFAMILY SSF89360 25 118 8.24E-27 T 09-03-2017 IPR000361 FeS cluster biogenesis ARZXY2_RS08375 a126c94e7f57155df8cda71d4767babd 129 Pfam PF01521 Iron-sulphur cluster biosynthesis 24 126 3.8E-17 T 09-03-2017 IPR000361 FeS cluster biogenesis ARZXY2_RS02890 5cc7caad4dbbd43a112d0b70f0fabcba 134 Gene3D G3DSA:3.10.180.10 3 129 5.4E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS02890 5cc7caad4dbbd43a112d0b70f0fabcba 134 SUPERFAMILY SSF54593 5 129 4.65E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 PIRSF PIRSF002161 7 191 3.2E-62 T 09-03-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 SUPERFAMILY SSF55282 13 188 2.28E-74 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 Gene3D G3DSA:3.30.1440.10 12 188 3.7E-75 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 Pfam PF00673 ribosomal L5P family C-terminus 94 187 2.2E-38 T 09-03-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 Pfam PF00281 Ribosomal protein L5 34 90 3.1E-27 T 09-03-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03555 ecbd24511bdbb18becf270a8134969fe 191 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 11 189 43.15 T 09-03-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS15355 9409d202f9d83452e9287cc2ce42e263 184 Pfam PF01661 Macro domain 19 136 2.6E-37 T 09-03-2017 IPR002589 Macro domain ARZXY2_RS15355 9409d202f9d83452e9287cc2ce42e263 184 SMART SM00506 2 136 1.7E-43 T 09-03-2017 IPR002589 Macro domain ARZXY2_RS15355 9409d202f9d83452e9287cc2ce42e263 184 Gene3D G3DSA:3.40.220.10 2 183 2.4E-58 T 09-03-2017 ARZXY2_RS15355 9409d202f9d83452e9287cc2ce42e263 184 SUPERFAMILY SSF52949 1 182 7.74E-51 T 09-03-2017 ARZXY2_RS01555 8d7407ed07fea65e78046d31b69fd198 270 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 4 269 1.5E-118 T 09-03-2017 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 ARZXY2_RS01555 8d7407ed07fea65e78046d31b69fd198 270 Pfam PF07883 Cupin domain 70 139 8.9E-9 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS01555 8d7407ed07fea65e78046d31b69fd198 270 Pfam PF07883 Cupin domain 192 257 6.0E-8 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS01555 8d7407ed07fea65e78046d31b69fd198 270 Gene3D G3DSA:2.60.120.10 4 268 3.4E-101 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS01555 8d7407ed07fea65e78046d31b69fd198 270 SUPERFAMILY SSF51182 18 269 8.74E-78 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 Gene3D G3DSA:3.30.360.10 132 240 4.0E-31 T 09-03-2017 ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 Gene3D G3DSA:3.30.360.10 275 328 4.0E-31 T 09-03-2017 ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 Gene3D G3DSA:3.40.50.720 3 131 1.6E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 9.5E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 SUPERFAMILY SSF55347 123 241 1.29E-19 T 09-03-2017 ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 SUPERFAMILY SSF51735 4 145 3.63E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04850 7d96bf7788aafc9e506423707a64e9aa 328 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 198 3.9E-7 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16835 9bce6329e520ba4ce67d2b9a957d7024 110 SUPERFAMILY SSF89957 5 108 4.06E-27 T 09-03-2017 IPR029756 MTH1187/YkoF-like ARZXY2_RS16835 9bce6329e520ba4ce67d2b9a957d7024 110 Gene3D G3DSA:3.30.70.930 1 107 2.3E-35 T 09-03-2017 IPR029756 MTH1187/YkoF-like ARZXY2_RS16835 9bce6329e520ba4ce67d2b9a957d7024 110 Pfam PF01910 Thiamine-binding protein 21 102 2.9E-27 T 09-03-2017 IPR002767 Thiamine-binding protein ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 SUPERFAMILY SSF89963 91 162 6.28E-22 T 09-03-2017 IPR007551 Protein of unknown function DUF520 ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 Pfam PF04461 Protein of unknown function (DUF520) 6 162 1.1E-56 T 09-03-2017 IPR007551 Protein of unknown function DUF520 ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 24.642 T 09-03-2017 IPR007551 Protein of unknown function DUF520 ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 Gene3D G3DSA:3.30.70.860 98 162 1.4E-27 T 09-03-2017 ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 SUPERFAMILY SSF89963 6 89 4.45E-27 T 09-03-2017 IPR007551 Protein of unknown function DUF520 ARZXY2_RS03015 f4002a8447cf34680efb1be00c227e3c 163 Gene3D G3DSA:3.30.70.990 12 97 2.4E-30 T 09-03-2017 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 Gene3D G3DSA:1.10.357.10 17 195 1.5E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 SUPERFAMILY SSF48498 89 197 1.02E-19 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 Pfam PF13977 Bacterial transcriptional repressor 127 188 6.9E-10 T 09-03-2017 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03130 8a7389b07a4736986f5fa1972b144a6a 201 SUPERFAMILY SSF46689 13 80 1.3E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09170 129243d476f0f29bc2effb3bfad91200 229 Gene3D G3DSA:3.30.70.240 158 228 2.5E-5 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain ARZXY2_RS09170 129243d476f0f29bc2effb3bfad91200 229 SUPERFAMILY SSF54211 19 147 8.72E-35 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold ARZXY2_RS09170 129243d476f0f29bc2effb3bfad91200 229 Pfam PF09186 Domain of unknown function (DUF1949) 158 213 1.1E-5 T 09-03-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal ARZXY2_RS09170 129243d476f0f29bc2effb3bfad91200 229 Gene3D G3DSA:3.30.230.30 20 148 1.1E-40 T 09-03-2017 IPR001498 Impact, N-terminal ARZXY2_RS09170 129243d476f0f29bc2effb3bfad91200 229 Pfam PF01205 Uncharacterized protein family UPF0029 28 140 2.0E-23 T 09-03-2017 IPR001498 Impact, N-terminal ARZXY2_RS10725 36f656c01d24f15fcb65bcbca1561184 145 Pfam PF06271 RDD family 41 138 2.6E-5 T 09-03-2017 IPR010432 RDD ARZXY2_RS10725 36f656c01d24f15fcb65bcbca1561184 145 PIRSF PIRSF021697 3 145 3.1E-45 T 09-03-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 ProSitePatterns PS00211 ABC transporters family signature. 1055 1069 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SUPERFAMILY SSF52540 325 525 2.61E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Pfam PF00664 ABC transporter transmembrane region 62 264 5.2E-15 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Gene3D G3DSA:3.40.50.300 331 524 5.0E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Gene3D G3DSA:1.20.1560.10 16 311 6.3E-26 T 09-03-2017 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Gene3D G3DSA:1.20.1560.10 584 882 3.9E-9 T 09-03-2017 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SMART SM00382 953 1136 8.6E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SMART SM00382 355 528 9.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Gene3D G3DSA:3.40.50.300 929 1133 2.6E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SUPERFAMILY SSF90123 14 311 2.75E-32 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SUPERFAMILY SSF52540 922 1126 5.59E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 583 1113 1.2E-152 T 09-03-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Pfam PF00005 ABC transporter 349 482 1.5E-13 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 Pfam PF00005 ABC transporter 945 1083 2.9E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 SUPERFAMILY SSF90123 583 882 2.49E-21 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS10615 64dc797038b402cd594511d2ab56a4ed 1145 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 524 7.4E-146 T 09-03-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 Pfam PF01261 Xylose isomerase-like TIM barrel 42 265 2.2E-25 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 Gene3D G3DSA:3.20.20.150 4 393 4.0E-137 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 Hamap MF_00455 Xylose isomerase [xylA]. 1 391 34.562 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 SUPERFAMILY SSF51658 5 394 6.55E-112 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 45 67 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 156 175 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 129 150 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 248 259 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 105 124 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 178 202 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 220 247 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 287 298 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 PRINTS PR00688 Xylose isomerase signature 82 102 6.7E-69 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS00250 62a638c120b2056992aa32d6130c21c0 395 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 4 392 1.9E-216 T 09-03-2017 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 ARZXY2_RS10985 dbabfebd36a9b88f803f20f6856f482d 238 Gene3D G3DSA:1.10.1660.10 13 120 4.6E-21 T 09-03-2017 ARZXY2_RS10985 dbabfebd36a9b88f803f20f6856f482d 238 SMART SM00422 12 86 1.8E-19 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS10985 dbabfebd36a9b88f803f20f6856f482d 238 SUPERFAMILY SSF46955 26 121 1.56E-15 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS10985 dbabfebd36a9b88f803f20f6856f482d 238 Pfam PF13411 MerR HTH family regulatory protein 27 85 2.4E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 SUPERFAMILY SSF52540 255 483 1.59E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 Pfam PF00005 ABC transporter 272 427 3.9E-15 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 Pfam PF00005 ABC transporter 19 168 7.5E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 Gene3D G3DSA:3.40.50.300 248 480 2.5E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 Gene3D G3DSA:3.40.50.300 2 225 9.9E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 SUPERFAMILY SSF52540 3 224 5.55E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 SMART SM00382 27 216 1.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13170 265f8c4e06fd3e3c47831fbd1095635c 507 SMART SM00382 280 476 8.2 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00930 eefbc55fc555bdf455bf064208567814 392 Pfam PF07690 Major Facilitator Superfamily 19 246 1.1E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00930 eefbc55fc555bdf455bf064208567814 392 SUPERFAMILY SSF103473 8 385 1.44E-44 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00930 eefbc55fc555bdf455bf064208567814 392 Gene3D G3DSA:1.20.1250.20 228 385 1.8E-22 T 09-03-2017 ARZXY2_RS00930 eefbc55fc555bdf455bf064208567814 392 Gene3D G3DSA:1.20.1250.20 11 187 1.1E-17 T 09-03-2017 ARZXY2_RS05145 9217f60c6a039da53ebf850beab7ada0 499 SUPERFAMILY SSF63380 276 371 8.06E-11 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS05145 9217f60c6a039da53ebf850beab7ada0 499 Gene3D G3DSA:2.40.30.10 279 357 4.2E-10 T 09-03-2017 ARZXY2_RS05145 9217f60c6a039da53ebf850beab7ada0 499 Gene3D G3DSA:3.40.50.80 358 490 4.1E-16 T 09-03-2017 ARZXY2_RS05145 9217f60c6a039da53ebf850beab7ada0 499 SUPERFAMILY SSF52343 371 496 5.5E-18 T 09-03-2017 ARZXY2_RS02630 56a6e121c12ed4b92ee3affcd2f74e4d 550 Pfam PF13524 Glycosyl transferases group 1 257 347 7.1E-12 T 09-03-2017 ARZXY2_RS02630 56a6e121c12ed4b92ee3affcd2f74e4d 550 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 118 190 2.3E-6 T 09-03-2017 IPR024542 Domain of unknown function DUF3880 ARZXY2_RS19975 4105a869f9a27e6339cd27b4687d3083 167 Gene3D G3DSA:3.40.630.30 50 156 7.7E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS19975 4105a869f9a27e6339cd27b4687d3083 167 SUPERFAMILY SSF55729 21 141 7.75E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS19975 4105a869f9a27e6339cd27b4687d3083 167 Pfam PF00583 Acetyltransferase (GNAT) family 61 135 7.4E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 422 4.7E-60 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 SUPERFAMILY SSF53850 44 499 2.9E-81 T 09-03-2017 ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 Gene3D G3DSA:3.10.105.10 303 480 5.0E-34 T 09-03-2017 ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 Gene3D G3DSA:3.40.190.10 192 302 1.4E-24 T 09-03-2017 ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 PIRSF PIRSF002741 5 509 3.6E-60 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 ARZXY2_RS16255 41391ba5b3bf3ea0fc4ac942fbbd2ad8 512 Gene3D G3DSA:3.90.76.10 53 191 1.2E-24 T 09-03-2017 ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 236 371 1.3E-28 T 09-03-2017 IPR012328 Chalcone/stilbene synthase, C-terminal ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 Gene3D G3DSA:3.40.47.10 228 372 2.1E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 Gene3D G3DSA:3.40.47.10 1 221 1.5E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 7 217 3.0E-31 T 09-03-2017 IPR001099 Chalcone/stilbene synthase, N-terminal ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 SUPERFAMILY SSF53901 2 373 3.53E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS08545 d172eab720aed4b0fc86b6b710ef8262 378 PIRSF PIRSF000451 1 375 1.7E-117 T 09-03-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 SUPERFAMILY SSF51445 26 378 3.79E-108 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 SUPERFAMILY SSF52317 405 613 1.95E-55 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 Pfam PF08532 Beta-galactosidase trimerisation domain 407 613 3.1E-61 T 09-03-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 PIRSF PIRSF001084 17 685 8.5E-241 T 09-03-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 Gene3D G3DSA:3.20.20.80 27 400 2.3E-120 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 Gene3D G3DSA:3.40.50.880 405 616 1.1E-64 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 Pfam PF08533 Beta-galactosidase C-terminal domain 638 683 4.4E-9 T 09-03-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS13695 107418b0fae7ec58c63f14656371aaed 690 Pfam PF02449 Beta-galactosidase 30 396 1.9E-136 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04115 dbe9ef336bea3b7fb9ef29a34ff5eda0 283 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 42 262 1.0E-72 T 09-03-2017 IPR022488 Polyphosphate kinase-2-related ARZXY2_RS04115 dbe9ef336bea3b7fb9ef29a34ff5eda0 283 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 15 276 1.3E-109 T 09-03-2017 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 ARZXY2_RS04115 dbe9ef336bea3b7fb9ef29a34ff5eda0 283 PIRSF PIRSF028756 15 281 3.7E-75 T 09-03-2017 IPR016898 Polyphosphate kinase 2 ARZXY2_RS04115 dbe9ef336bea3b7fb9ef29a34ff5eda0 283 Gene3D G3DSA:3.40.50.300 12 276 8.6E-94 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04115 dbe9ef336bea3b7fb9ef29a34ff5eda0 283 SUPERFAMILY SSF52540 78 261 8.86E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09495 726e3a41ec4bc74f566703b0f92cf125 230 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 208 1.3E-93 T 09-03-2017 IPR022492 Phosphomutase MSMEG4193, putative ARZXY2_RS09495 726e3a41ec4bc74f566703b0f92cf125 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 1.9E-44 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS09495 726e3a41ec4bc74f566703b0f92cf125 230 SMART SM00855 3 163 9.9E-20 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS09495 726e3a41ec4bc74f566703b0f92cf125 230 SUPERFAMILY SSF53254 1 201 3.33E-42 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS09495 726e3a41ec4bc74f566703b0f92cf125 230 Gene3D G3DSA:3.40.50.1240 2 202 5.7E-43 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS01290 d455d085cfb1f662d9c3365d2e819877 248 Gene3D G3DSA:3.40.50.880 3 237 1.9E-86 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS01290 d455d085cfb1f662d9c3365d2e819877 248 Pfam PF06283 Trehalose utilisation 7 226 1.1E-30 T 09-03-2017 IPR029010 ThuA-like domain ARZXY2_RS01290 d455d085cfb1f662d9c3365d2e819877 248 SUPERFAMILY SSF52317 4 236 8.24E-58 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS01290 d455d085cfb1f662d9c3365d2e819877 248 PIRSF PIRSF030013 5 243 4.5E-105 T 09-03-2017 IPR009381 Trehalose catabolism protein, ThuA, prokaryote ARZXY2_RS02115 d987da0911467ce693123110ddd8e78c 271 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 22 211 4.9E-15 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 ARZXY2_RS02115 d987da0911467ce693123110ddd8e78c 271 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 22 222 8.9E-54 T 09-03-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial ARZXY2_RS02115 d987da0911467ce693123110ddd8e78c 271 Pfam PF12710 haloacid dehalogenase-like hydrolase 23 208 4.4E-27 T 09-03-2017 ARZXY2_RS02115 d987da0911467ce693123110ddd8e78c 271 SUPERFAMILY SSF56784 22 239 7.74E-30 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS02115 d987da0911467ce693123110ddd8e78c 271 Gene3D G3DSA:3.40.50.1000 94 239 1.5E-47 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 SMART SM00421 144 201 3.6E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 2.1E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 2.1E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 2.1E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 Pfam PF00072 Response regulator receiver domain 6 118 2.8E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 SUPERFAMILY SSF52172 4 135 3.84E-33 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 3.1E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 Gene3D G3DSA:3.40.50.2300 2 148 3.4E-38 T 09-03-2017 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 Gene3D G3DSA:1.10.10.10 149 204 9.6E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 SMART SM00448 4 118 1.0E-32 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS16550 e64d8488c8a5b7b6324932631442aa65 208 SUPERFAMILY SSF46894 135 204 1.09E-19 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 SMART SM00382 25 222 5.6E-23 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 PIRSF PIRSF039085 1 250 1.5E-113 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 SUPERFAMILY SSF52540 2 244 1.19E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 Pfam PF00005 ABC transporter 16 174 1.5E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS00080 0014a2ae3e4f48105c5937bfe0300de7 255 Gene3D G3DSA:3.40.50.300 2 246 3.5E-84 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 SUPERFAMILY SSF51905 167 283 6.97E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 SUPERFAMILY SSF51905 338 413 6.97E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 134 4.2E-9 T 09-03-2017 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 4.2E-9 T 09-03-2017 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.2E-9 T 09-03-2017 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 Gene3D G3DSA:3.50.50.60 8 136 5.9E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 Gene3D G3DSA:3.50.50.60 348 411 5.9E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 SUPERFAMILY SSF51905 5 208 1.88E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 197 8.0E-24 T 09-03-2017 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 Gene3D G3DSA:3.50.50.60 263 283 2.2E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13530 b63f8d04e5ea01dda03e4b84d53ee600 413 Gene3D G3DSA:3.50.50.60 137 203 2.2E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04065 5b590d583c0d04932bac3d05ecfc62d0 343 Pfam PF03060 Nitronate monooxygenase 7 340 6.1E-71 T 09-03-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 ARZXY2_RS04065 5b590d583c0d04932bac3d05ecfc62d0 343 SUPERFAMILY SSF51412 4 67 4.88E-48 T 09-03-2017 ARZXY2_RS04065 5b590d583c0d04932bac3d05ecfc62d0 343 SUPERFAMILY SSF51412 108 293 4.88E-48 T 09-03-2017 ARZXY2_RS04065 5b590d583c0d04932bac3d05ecfc62d0 343 Gene3D G3DSA:3.20.20.70 4 311 1.6E-54 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 SUPERFAMILY SSF56042 596 768 1.5E-32 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 32 767 7.5E-251 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 SUPERFAMILY SSF55326 424 592 2.62E-54 T 09-03-2017 ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Gene3D G3DSA:3.30.1330.10 441 589 3.8E-55 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Gene3D G3DSA:3.30.1330.10 64 213 7.8E-49 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Pfam PF00586 AIR synthase related protein, N-terminal domain 467 585 1.8E-23 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Pfam PF00586 AIR synthase related protein, N-terminal domain 106 208 2.7E-20 T 09-03-2017 IPR016188 PurM-like, N-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 PIRSF PIRSF001587 9 769 2.2E-281 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 SUPERFAMILY SSF55326 27 213 3.29E-48 T 09-03-2017 ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Pfam PF02769 AIR synthase related protein, C-terminal domain 221 376 1.2E-26 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Pfam PF02769 AIR synthase related protein, C-terminal domain 600 740 4.3E-17 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 SUPERFAMILY SSF56042 219 453 2.84E-47 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain ARZXY2_RS15915 fad86323ebbf83309bfd90f6cfa5b28a 769 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 769 293.124 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 SMART SM00670 38 165 1.9E-16 T 09-03-2017 IPR002716 PIN domain ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 Gene3D G3DSA:3.40.50.300 254 459 4.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 Pfam PF02562 PhoH-like protein 255 458 6.0E-55 T 09-03-2017 IPR003714 PhoH-like protein GO:0005524 ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 SUPERFAMILY SSF88723 130 177 1.57E-10 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 SUPERFAMILY SSF88723 39 97 1.57E-10 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 SUPERFAMILY SSF52540 253 414 7.26E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 Pfam PF13638 PIN domain 40 178 1.4E-26 T 09-03-2017 IPR002716 PIN domain ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 Gene3D G3DSA:3.40.50.1010 38 97 5.7E-12 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS12980 c4b661efbff92e44b2b9097148f28cbf 464 Gene3D G3DSA:3.40.50.1010 130 178 5.7E-12 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS13275 1b42af05d4fb5955443016fc746c051e 309 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13275 1b42af05d4fb5955443016fc746c051e 309 SMART SM00382 31 213 1.7E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13275 1b42af05d4fb5955443016fc746c051e 309 Gene3D G3DSA:3.40.50.300 4 235 2.9E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13275 1b42af05d4fb5955443016fc746c051e 309 SUPERFAMILY SSF52540 5 228 3.91E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13275 1b42af05d4fb5955443016fc746c051e 309 Pfam PF00005 ABC transporter 22 165 4.5E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 9.1E-44 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 Pfam PF02780 Transketolase, C-terminal domain 197 317 6.4E-36 T 09-03-2017 IPR033248 Transketolase, C-terminal domain ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 SUPERFAMILY SSF52518 3 183 3.59E-65 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 SMART SM00861 4 179 5.9E-65 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 SUPERFAMILY SSF52922 193 325 5.5E-36 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 Gene3D G3DSA:3.40.50.920 200 321 1.4E-40 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 ARZXY2_RS11725 ca72e9a454100dd4af29d7748150609a 336 Gene3D G3DSA:3.40.50.970 2 198 1.0E-73 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS06985 7ed608ce89df94c309d884eb8bb45a74 597 Pfam PF01964 Radical SAM ThiC family 123 543 2.0E-201 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 ARZXY2_RS06985 7ed608ce89df94c309d884eb8bb45a74 597 Pfam PF13667 ThiC-associated domain 22 80 4.9E-9 T 09-03-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 ARZXY2_RS06985 7ed608ce89df94c309d884eb8bb45a74 597 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 122 549 55.816 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 ARZXY2_RS06985 7ed608ce89df94c309d884eb8bb45a74 597 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 122 546 3.7E-212 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 SUPERFAMILY SSF52540 273 392 5.11E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 SUPERFAMILY SSF52540 141 211 5.11E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 Gene3D G3DSA:3.40.50.300 24 182 3.3E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 Gene3D G3DSA:3.40.50.300 287 392 3.4E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 SMART SM00487 23 201 2.7E-8 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 SUPERFAMILY SSF52540 23 184 1.63E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05350 6cfdbefe4d66ee5479437e98801b3463 590 Pfam PF04851 Type III restriction enzyme, res subunit 26 179 8.5E-13 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ARZXY2_RS00525 cf4410b47c50c52f745c05c7b189fec0 207 Pfam PF01810 LysE type translocator 16 205 1.1E-40 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS00525 cf4410b47c50c52f745c05c7b189fec0 207 PIRSF PIRSF006324 1 207 9.6E-57 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 255 273 9.7E-10 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 150 172 9.7E-10 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 19 36 9.7E-10 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 18 273 6.0E-55 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 Gene3D G3DSA:2.120.10.30 11 284 8.1E-66 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS16120 b4d4a3d22005a1fdd75928c4751be36e 293 SUPERFAMILY SSF63829 7 284 4.36E-57 T 09-03-2017 ARZXY2_RS07825 635b128f85498839ce589d893b63a188 445 Pfam PF01844 HNH endonuclease 360 397 1.4E-8 T 09-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 ARZXY2_RS07825 635b128f85498839ce589d893b63a188 445 SMART SM00507 344 394 1.8E-8 T 09-03-2017 IPR003615 HNH nuclease ARZXY2_RS07825 635b128f85498839ce589d893b63a188 445 Pfam PF02720 Domain of unknown function (DUF222) 48 249 8.0E-12 T 09-03-2017 IPR003870 Domain of unknown function DUF222 ARZXY2_RS16955 fe4a4bddaa7d61cfa90d6f2738790744 159 Gene3D G3DSA:3.10.129.10 2 149 3.6E-44 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS16955 fe4a4bddaa7d61cfa90d6f2738790744 159 Pfam PF01575 MaoC like domain 10 122 5.9E-23 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS16955 fe4a4bddaa7d61cfa90d6f2738790744 159 SUPERFAMILY SSF54637 1 149 8.75E-43 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS03050 64dfbd07a7135ad0c720c1f9878e9b0c 335 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS03050 64dfbd07a7135ad0c720c1f9878e9b0c 335 SUPERFAMILY SSF52540 16 236 3.97E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03050 64dfbd07a7135ad0c720c1f9878e9b0c 335 Gene3D G3DSA:3.40.50.300 19 237 2.4E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03050 64dfbd07a7135ad0c720c1f9878e9b0c 335 SMART SM00382 46 250 3.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS03050 64dfbd07a7135ad0c720c1f9878e9b0c 335 Pfam PF00005 ABC transporter 37 176 8.5E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS19235 553bc0a0a37a00b5f019edba88dc3103 173 Gene3D G3DSA:3.40.50.880 3 172 9.2E-50 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS19235 553bc0a0a37a00b5f019edba88dc3103 173 Pfam PF01965 DJ-1/PfpI family 7 169 4.7E-49 T 09-03-2017 IPR002818 DJ-1/PfpI ARZXY2_RS19235 553bc0a0a37a00b5f019edba88dc3103 173 SUPERFAMILY SSF52317 6 172 1.63E-47 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS19235 553bc0a0a37a00b5f019edba88dc3103 173 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 7 172 3.3E-53 T 09-03-2017 IPR006286 Peptidase C56, PfpI ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 Gene3D G3DSA:3.90.1150.10 256 380 3.9E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 Gene3D G3DSA:3.40.640.10 50 255 2.3E-40 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 Pfam PF00155 Aminotransferase class I and II 34 378 4.6E-41 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 12 378 6.1E-176 T 09-03-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 ARZXY2_RS04255 d5442c1b29665911d534d2d4092a790c 382 SUPERFAMILY SSF53383 12 380 3.81E-76 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 SUPERFAMILY SSF51735 12 169 6.22E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 Pfam PF14100 Methane oxygenase PmoA 397 677 6.9E-69 T 09-03-2017 IPR029475 Methane oxygenase PmoA ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 Gene3D G3DSA:3.40.50.720 19 155 5.0E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 Gene3D G3DSA:3.30.360.10 156 339 1.6E-14 T 09-03-2017 ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 SUPERFAMILY SSF55347 149 301 8.5E-11 T 09-03-2017 ARZXY2_RS01995 5de9d7bdc2d74393c93092165ec6cb85 684 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 19 141 2.7E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 26.58 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 141 2.2E-58 T 09-03-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 Gene3D G3DSA:3.90.1180.10 3 141 7.7E-61 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 SUPERFAMILY SSF52161 4 144 4.58E-57 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 PIRSF PIRSF002181 2 147 2.3E-45 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03730 3a2b212e7d7c700579bb8a8c041f730d 147 Pfam PF00572 Ribosomal protein L13 14 138 4.3E-55 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS01525 a04453873d5146f5ef053aa4e0c1a574 243 Gene3D G3DSA:3.40.50.880 18 225 2.5E-33 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS01525 a04453873d5146f5ef053aa4e0c1a574 243 Pfam PF00117 Glutamine amidotransferase class-I 49 193 1.3E-10 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS01525 a04453873d5146f5ef053aa4e0c1a574 243 SUPERFAMILY SSF52317 42 238 7.59E-30 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 Pfam PF04452 RNA methyltransferase 24 250 1.0E-56 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 SUPERFAMILY SSF88697 18 72 4.22E-8 T 09-03-2017 IPR015947 PUA-like domain ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 PIRSF PIRSF015601 15 257 2.7E-46 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 SUPERFAMILY SSF75217 79 257 2.2E-42 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 22 251 9.0E-34 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS08285 69083d407e73f4c9ff836112a1f9a481 258 Gene3D G3DSA:3.40.1280.10 16 258 3.5E-65 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS02080 2fafa91d6aa853e4728a0fd918306361 290 SUPERFAMILY SSF161098 8 290 1.64E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02080 2fafa91d6aa853e4728a0fd918306361 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 283 2.4E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02080 2fafa91d6aa853e4728a0fd918306361 290 Gene3D G3DSA:1.10.3720.10 3 277 1.3E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02685 fd6b2ce0896ca805ab228a6eab63db42 323 Gene3D G3DSA:3.40.50.1820 154 246 8.0E-4 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02685 fd6b2ce0896ca805ab228a6eab63db42 323 SUPERFAMILY SSF53474 62 193 9.42E-6 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02685 fd6b2ce0896ca805ab228a6eab63db42 323 SUPERFAMILY SSF53474 151 312 4.1E-5 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 Gene3D G3DSA:3.40.50.620 4 146 4.8E-28 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 PRINTS PR01438 Universal stress protein signature 107 119 9.7E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 PRINTS PR01438 Universal stress protein signature 125 147 9.7E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 PRINTS PR01438 Universal stress protein signature 7 25 9.7E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 SUPERFAMILY SSF52402 8 147 1.0E-25 T 09-03-2017 ARZXY2_RS09815 05f7c740f30da12875679c7caf686373 153 Pfam PF00582 Universal stress protein family 8 146 1.8E-22 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS18295 6069630ed00294cd8cac21c3b1b80527 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS18295 6069630ed00294cd8cac21c3b1b80527 309 Pfam PF00294 pfkB family carbohydrate kinase 2 301 8.3E-42 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS18295 6069630ed00294cd8cac21c3b1b80527 309 Gene3D G3DSA:3.40.1190.20 2 308 1.2E-68 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS18295 6069630ed00294cd8cac21c3b1b80527 309 SUPERFAMILY SSF53613 3 306 1.71E-61 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS00945 5541367e104542f09debdc36648741ac 170 Pfam PF03640 Secreted repeat of unknown function 114 155 8.1E-18 T 09-03-2017 IPR005297 Lipoprotein repeat ARZXY2_RS00945 5541367e104542f09debdc36648741ac 170 Pfam PF03640 Secreted repeat of unknown function 52 96 8.1E-15 T 09-03-2017 IPR005297 Lipoprotein repeat ARZXY2_RS06145 5d38bc1fa8e1c22806f627fa489de15a 73 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ARZXY2_RS06145 5d38bc1fa8e1c22806f627fa489de15a 73 SUPERFAMILY SSF55008 1 68 1.44E-13 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06145 5d38bc1fa8e1c22806f627fa489de15a 73 Gene3D G3DSA:3.30.70.100 1 68 2.0E-19 T 09-03-2017 ARZXY2_RS06145 5d38bc1fa8e1c22806f627fa489de15a 73 Pfam PF00403 Heavy-metal-associated domain 4 66 3.7E-12 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS10630 0f38960063bd7dfec49127aef1735a55 126 Pfam PF03965 Penicillinase repressor 4 125 1.2E-19 T 09-03-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 ARZXY2_RS10630 0f38960063bd7dfec49127aef1735a55 126 Gene3D G3DSA:1.10.10.10 2 91 1.0E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10630 0f38960063bd7dfec49127aef1735a55 126 SUPERFAMILY SSF46785 2 125 1.52E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01215 651460d8a1d2fc5f5f121a972ff751ab 279 SMART SM00862 189 263 1.6E-15 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS01215 651460d8a1d2fc5f5f121a972ff751ab 279 Pfam PF00486 Transcriptional regulatory protein, C terminal 189 263 3.3E-12 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 ARZXY2_RS01215 651460d8a1d2fc5f5f121a972ff751ab 279 SUPERFAMILY SSF46894 174 264 2.78E-16 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS01215 651460d8a1d2fc5f5f121a972ff751ab 279 Gene3D G3DSA:1.10.10.10 174 265 1.9E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 Gene3D G3DSA:1.20.200.10 126 395 1.1E-82 T 09-03-2017 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 ProSitePatterns PS00163 Fumarate lyases signature. 300 309 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 Pfam PF08328 Adenylosuccinate lyase C-terminal 337 457 3.9E-44 T 09-03-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 PRINTS PR00149 Fumarate lyase superfamily signature 300 316 6.5E-17 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 PRINTS PR00149 Fumarate lyase superfamily signature 123 141 6.5E-17 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 PRINTS PR00149 Fumarate lyase superfamily signature 169 187 6.5E-17 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 PRINTS PR00149 Fumarate lyase superfamily signature 257 284 6.5E-17 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 Gene3D G3DSA:1.10.275.10 13 125 9.0E-35 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 SUPERFAMILY SSF48557 19 466 9.42E-93 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 Gene3D G3DSA:1.10.40.30 396 457 6.0E-26 T 09-03-2017 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 19 467 1.1E-101 T 09-03-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS19985 57f7ad8ec69e43ab583b62030eab23c6 468 Pfam PF00206 Lyase 21 316 1.4E-47 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal ARZXY2_RS00305 9516575959387b2e8b79cfdee4715929 158 Pfam PF12680 SnoaL-like domain 16 115 9.6E-17 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS00305 9516575959387b2e8b79cfdee4715929 158 SUPERFAMILY SSF54427 12 125 7.53E-21 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS00305 9516575959387b2e8b79cfdee4715929 158 Gene3D G3DSA:3.10.450.50 5 128 3.6E-17 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 3.7E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.7E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.7E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.7E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 SMART SM00347 28 128 9.0E-16 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 Pfam PF12802 MarR family 36 92 5.3E-11 T 09-03-2017 ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 Gene3D G3DSA:1.10.10.10 26 138 2.8E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20250 9b34595d3ecb06e19727f54d7d25d35d 147 SUPERFAMILY SSF46785 11 139 6.65E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20570 6ace3220dd4b80fbc7873f991b630701 356 Gene3D G3DSA:3.40.50.1980 191 317 8.2E-17 T 09-03-2017 ARZXY2_RS20570 6ace3220dd4b80fbc7873f991b630701 356 SUPERFAMILY SSF53807 52 347 4.71E-49 T 09-03-2017 ARZXY2_RS20570 6ace3220dd4b80fbc7873f991b630701 356 Gene3D G3DSA:3.40.50.1980 66 190 3.9E-26 T 09-03-2017 ARZXY2_RS20570 6ace3220dd4b80fbc7873f991b630701 356 Pfam PF01497 Periplasmic binding protein 70 317 1.8E-29 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 Gene3D G3DSA:3.40.50.1860 32 204 1.5E-49 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 TIGRFAM TIGR00067 glut_race: glutamate racemase 34 283 3.4E-66 T 09-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 211 221 - T 09-03-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 SUPERFAMILY SSF53681 141 294 9.65E-39 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 Hamap MF_00258 Glutamate racemase [murI]. 32 287 35.798 T 09-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 Pfam PF01177 Asp/Glu/Hydantoin racemase 34 245 3.6E-30 T 09-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS05375 d6ead6183be12c0e667df8b693fd8ec9 344 SUPERFAMILY SSF53681 33 139 4.84E-30 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS15855 95700ef058eb19d8a906064092a87b4d 197 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 140 181 1.0E-8 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15855 95700ef058eb19d8a906064092a87b4d 197 Gene3D G3DSA:3.30.350.10 82 186 1.3E-24 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15855 95700ef058eb19d8a906064092a87b4d 197 SUPERFAMILY SSF55399 98 187 1.7E-22 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15855 95700ef058eb19d8a906064092a87b4d 197 Pfam PF00720 Subtilisin inhibitor-like 99 169 3.1E-6 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS10050 86dc5ff86fc97373862e87778f495e56 318 Pfam PF03741 Integral membrane protein TerC family 69 271 1.0E-47 T 09-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 ARZXY2_RS10050 86dc5ff86fc97373862e87778f495e56 318 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 318 1.1E-103 T 09-03-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 ARZXY2_RS08365 bedf1195f34c95034cbaa8b0f98030f6 197 Pfam PF11241 Protein of unknown function (DUF3043) 28 194 2.0E-58 T 09-03-2017 IPR021403 Protein of unknown function DUF3043 ARZXY2_RS10980 84c2f38d98680aa0b8606c649b3df5a0 167 SUPERFAMILY SSF103256 1 136 4.32E-41 T 09-03-2017 IPR003729 Bifunctional nuclease domain GO:0004518 ARZXY2_RS10980 84c2f38d98680aa0b8606c649b3df5a0 167 Pfam PF02577 Bifunctional nuclease 6 128 3.7E-41 T 09-03-2017 IPR003729 Bifunctional nuclease domain GO:0004518 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 Gene3D G3DSA:3.40.50.1970 12 176 1.5E-55 T 09-03-2017 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 Pfam PF01761 3-dehydroquinate synthase 72 327 3.5E-97 T 09-03-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 Gene3D G3DSA:1.20.1090.10 177 353 6.2E-64 T 09-03-2017 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 PIRSF PIRSF001455 9 361 1.2E-99 T 09-03-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 37.864 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 348 1.2E-110 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 ARZXY2_RS08090 962cf4263fc5e4b879091c478cad03ad 363 SUPERFAMILY SSF56796 17 359 4.97E-104 T 09-03-2017 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 SMART SM01130 13 301 9.6E-40 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 9.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 PRINTS PR00146 Dihydrodipicolinate synthase signature 48 69 9.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 9.3E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 SUPERFAMILY SSF51569 13 298 6.18E-47 T 09-03-2017 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 Gene3D G3DSA:3.20.20.70 13 301 5.0E-49 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 PIRSF PIRSF001365 13 311 1.7E-33 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS13900 dbb62f0adeb7a5a15c3aa48750061d7d 313 Pfam PF00701 Dihydrodipicolinate synthetase family 15 299 8.8E-19 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 Pfam PF00817 impB/mucB/samB family 7 150 2.7E-30 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 SUPERFAMILY SSF56672 4 239 1.6E-63 T 09-03-2017 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 Gene3D G3DSA:1.10.150.20 170 242 1.7E-16 T 09-03-2017 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 Pfam PF11799 impB/mucB/samB family C-terminal domain 245 354 5.2E-7 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 Gene3D G3DSA:3.30.70.270 69 157 7.4E-20 T 09-03-2017 ARZXY2_RS17715 2fc95a20453a4b2bacddf4ca63fa208f 423 Pfam PF13438 Domain of unknown function (DUF4113) 374 420 1.4E-16 T 09-03-2017 IPR025188 Domain of unknown function DUF4113 ARZXY2_RS18580 5e894bc42a8c28f4c09b0002d017ed67 161 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 71 124 3.0E-24 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor ARZXY2_RS18580 5e894bc42a8c28f4c09b0002d017ed67 161 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 57 125 23.236 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor ARZXY2_RS18580 5e894bc42a8c28f4c09b0002d017ed67 161 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 61 127 4.4E-25 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor ARZXY2_RS18580 5e894bc42a8c28f4c09b0002d017ed67 161 Pfam PF01809 Haemolytic domain 59 124 1.4E-26 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor ARZXY2_RS18580 5e894bc42a8c28f4c09b0002d017ed67 161 SMART SM01234 57 124 6.0E-40 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor ARZXY2_RS16740 327ec2700d155de63cd0d142defb8606 202 Gene3D G3DSA:3.50.50.60 6 129 5.7E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16740 327ec2700d155de63cd0d142defb8606 202 Pfam PF01494 FAD binding domain 9 142 6.1E-6 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS16740 327ec2700d155de63cd0d142defb8606 202 SUPERFAMILY SSF51905 5 164 1.73E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13225 eed5008464fef9ae09b299a2230d0517 261 SUPERFAMILY SSF53474 183 251 1.94E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS13225 eed5008464fef9ae09b299a2230d0517 261 SUPERFAMILY SSF53474 3 139 1.94E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS13225 eed5008464fef9ae09b299a2230d0517 261 Pfam PF12146 Serine aminopeptidase, S33 41 138 2.3E-10 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS13225 eed5008464fef9ae09b299a2230d0517 261 Gene3D G3DSA:3.40.50.1820 183 253 2.8E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS13225 eed5008464fef9ae09b299a2230d0517 261 Gene3D G3DSA:3.40.50.1820 5 140 2.8E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19325 dfc705f6ba8fb2a445fb635817ee3fdb 442 Pfam PF00860 Permease family 20 395 5.7E-26 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS16940 e6bb649d4314b79c9c11847c6879fd8e 158 Pfam PF01575 MaoC like domain 27 125 7.9E-22 T 09-03-2017 IPR002539 MaoC-like domain ARZXY2_RS16940 e6bb649d4314b79c9c11847c6879fd8e 158 Gene3D G3DSA:3.10.129.10 14 158 5.9E-40 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS16940 e6bb649d4314b79c9c11847c6879fd8e 158 SUPERFAMILY SSF54637 14 158 7.47E-35 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS05150 b6fad21b2c85a893d990f913a1b141d6 290 SUPERFAMILY SSF143631 9 288 1.73E-50 T 09-03-2017 IPR003374 ApbE-like domain ARZXY2_RS05150 b6fad21b2c85a893d990f913a1b141d6 290 Pfam PF02424 ApbE family 15 258 2.4E-40 T 09-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 ARZXY2_RS12380 20ee055ca709071ed50fb086fa1e159d 170 Gene3D G3DSA:3.40.630.30 4 153 1.6E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12380 20ee055ca709071ed50fb086fa1e159d 170 SUPERFAMILY SSF55729 4 166 2.74E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12380 20ee055ca709071ed50fb086fa1e159d 170 Pfam PF00583 Acetyltransferase (GNAT) family 58 143 7.6E-11 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS10445 bcbfae62890df4faf67cd62c5253769d 429 Gene3D G3DSA:3.40.50.1820 148 288 5.3E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10445 bcbfae62890df4faf67cd62c5253769d 429 Gene3D G3DSA:3.40.50.1820 335 406 5.3E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10445 bcbfae62890df4faf67cd62c5253769d 429 SUPERFAMILY SSF53474 125 408 1.77E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10445 bcbfae62890df4faf67cd62c5253769d 429 Pfam PF00326 Prolyl oligopeptidase family 224 407 6.9E-10 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ARZXY2_RS20510 eecdae019a624e2ab1ac52f17efbdb24 109 SUPERFAMILY SSF55174 1 77 1.13E-17 T 09-03-2017 ARZXY2_RS20510 eecdae019a624e2ab1ac52f17efbdb24 109 PIRSF PIRSF016821 1 109 3.3E-38 T 09-03-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 ARZXY2_RS20510 eecdae019a624e2ab1ac52f17efbdb24 109 Gene3D G3DSA:3.10.290.10 1 84 7.0E-25 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS20510 eecdae019a624e2ab1ac52f17efbdb24 109 Pfam PF01479 S4 domain 2 41 8.9E-8 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 25 36 2.7E-5 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 119 132 2.7E-5 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 165 2.7E-5 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 Gene3D G3DSA:3.40.50.1000 14 39 7.8E-35 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 Gene3D G3DSA:3.40.50.1000 110 220 7.8E-35 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 27 210 2.5E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 210 2.3E-22 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08680 a7b21e9bbe7c04028f7bc44a31588fb2 261 SUPERFAMILY SSF56784 25 213 1.47E-42 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09395 6b031d82a49c23765bc25e2ab9a62354 158 SUPERFAMILY SSF50475 9 135 6.09E-28 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09395 6b031d82a49c23765bc25e2ab9a62354 158 Gene3D G3DSA:2.30.110.10 8 143 7.7E-40 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09395 6b031d82a49c23765bc25e2ab9a62354 158 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 16 134 3.2E-22 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 68 142 4.0E-5 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 SUPERFAMILY SSF56349 64 283 1.01E-6 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 Gene3D G3DSA:1.10.443.10 210 295 1.5E-22 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 Gene3D G3DSA:1.10.443.10 355 461 1.5E-22 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 Gene3D G3DSA:1.10.150.130 67 150 3.3E-8 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 SUPERFAMILY SSF56349 209 282 1.25E-15 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06725 179976594aa157cd6ef7547164fee704 512 SUPERFAMILY SSF56349 342 463 1.25E-15 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS09685 8d079614b547df98d6a03e53b1f710f9 322 Pfam PF13407 Periplasmic binding protein domain 42 299 2.2E-52 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS09685 8d079614b547df98d6a03e53b1f710f9 322 Gene3D G3DSA:3.40.50.2300 40 156 3.0E-26 T 09-03-2017 ARZXY2_RS09685 8d079614b547df98d6a03e53b1f710f9 322 Gene3D G3DSA:3.40.50.2300 157 321 3.4E-45 T 09-03-2017 ARZXY2_RS09685 8d079614b547df98d6a03e53b1f710f9 322 SUPERFAMILY SSF53822 38 321 1.19E-74 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS07230 fc6c45578c70616778c5073135dcccf5 260 SUPERFAMILY SSF56281 4 245 1.04E-17 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07230 fc6c45578c70616778c5073135dcccf5 260 Gene3D G3DSA:3.60.15.10 2 257 2.7E-36 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07230 fc6c45578c70616778c5073135dcccf5 260 Pfam PF12706 Beta-lactamase superfamily domain 22 219 1.7E-13 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS06390 51ea4d48246d9902b5ba444b885557b4 583 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 190 480 3.0E-42 T 09-03-2017 IPR006500 DNA primase, phage/plasmid ARZXY2_RS06390 51ea4d48246d9902b5ba444b885557b4 583 Pfam PF03288 Poxvirus D5 protein-like 445 500 1.8E-5 T 09-03-2017 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal ARZXY2_RS06390 51ea4d48246d9902b5ba444b885557b4 583 Gene3D G3DSA:3.40.50.300 261 415 3.7E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06390 51ea4d48246d9902b5ba444b885557b4 583 SUPERFAMILY SSF52540 234 415 2.92E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 Gene3D G3DSA:3.40.50.20 1 92 8.1E-20 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 1 350 1.3E-99 T 09-03-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 Gene3D G3DSA:3.30.470.20 141 366 7.0E-76 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 SUPERFAMILY SSF51246 294 353 1.26E-12 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 Gene3D G3DSA:3.30.1490.20 96 140 1.9E-13 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 1 347 33.812 T 09-03-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 SUPERFAMILY SSF56059 86 287 9.9E-58 T 09-03-2017 ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 Pfam PF02222 ATP-grasp domain 95 267 1.3E-49 T 09-03-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type ARZXY2_RS12920 ce55fe3c86a971130c305a44a65912d2 378 SUPERFAMILY SSF52440 1 81 5.47E-14 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 472 2.7E-202 T 09-03-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 3.6E-23 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 3.6E-23 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 3.6E-23 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 3.6E-23 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 SUPERFAMILY SSF46548 12 155 1.46E-33 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Gene3D G3DSA:3.50.50.60 235 398 5.0E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Gene3D G3DSA:1.10.1060.10 11 147 1.0E-37 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 131 6.4E-21 T 09-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Gene3D G3DSA:3.40.50.720 399 479 2.4E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Gene3D G3DSA:3.40.50.720 148 234 2.4E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 SUPERFAMILY SSF51971 143 399 4.06E-68 T 09-03-2017 ARZXY2_RS10245 15dbbef07e45bce8e11cc5340ad8fc2b 485 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 454 9.1E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS10970 4d868fa09875f7d05480d6a9d1139f16 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 206 7.2E-30 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain ARZXY2_RS10970 4d868fa09875f7d05480d6a9d1139f16 270 Gene3D G3DSA:3.40.50.300 2 261 5.2E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS10970 4d868fa09875f7d05480d6a9d1139f16 270 SUPERFAMILY SSF52540 2 259 4.03E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03805 c7b77612621d46599cfbe37c622aed5f 171 Pfam PF13420 Acetyltransferase (GNAT) domain 12 152 2.2E-10 T 09-03-2017 ARZXY2_RS03805 c7b77612621d46599cfbe37c622aed5f 171 Gene3D G3DSA:3.40.630.30 9 168 1.9E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03805 c7b77612621d46599cfbe37c622aed5f 171 SUPERFAMILY SSF55729 6 168 4.12E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 Gene3D G3DSA:1.10.1660.10 58 108 3.5E-5 T 09-03-2017 ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 Pfam PF07739 TipAS antibiotic-recognition domain 127 247 2.3E-28 T 09-03-2017 IPR012925 TipAS antibiotic-recognition domain ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 Gene3D G3DSA:1.10.490.50 156 251 9.4E-26 T 09-03-2017 IPR012925 TipAS antibiotic-recognition domain ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 SMART SM00422 3 72 1.9E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 SUPERFAMILY SSF89082 158 251 1.15E-15 T 09-03-2017 IPR012925 TipAS antibiotic-recognition domain ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 Gene3D G3DSA:1.10.1660.10 3 57 4.8E-22 T 09-03-2017 ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 SUPERFAMILY SSF46955 3 109 3.19E-26 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS16285 12739e93e65b164b93033cbe1700b144 252 Pfam PF13411 MerR HTH family regulatory protein 4 70 5.6E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 244 5.4E-85 T 09-03-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 213 2.9E-25 T 09-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 39.975 T 09-03-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 Gene3D G3DSA:3.40.50.1360 1 258 8.0E-97 T 09-03-2017 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 09-03-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 ARZXY2_RS05340 c7ccddfa57fc4a8a961bb050adf86e2a 260 SUPERFAMILY SSF100950 1 251 6.05E-92 T 09-03-2017 ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 Pfam PF06580 Histidine kinase 189 266 1.2E-23 T 09-03-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 SUPERFAMILY SSF55781 74 181 9.42E-6 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 Gene3D G3DSA:3.30.565.10 249 387 5.8E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 SMART SM00387 282 387 8.1E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 386 3.0E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11760 3f6192ba93d760933fc34b48042976d8 392 SUPERFAMILY SSF55874 245 384 3.14E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS00540 3396f6e555b5d912f66c887612e151bc 326 SUPERFAMILY SSF51430 1 318 1.7E-75 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS00540 3396f6e555b5d912f66c887612e151bc 326 Pfam PF00248 Aldo/keto reductase family 16 303 9.3E-62 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS00540 3396f6e555b5d912f66c887612e151bc 326 Gene3D G3DSA:3.20.20.100 1 314 1.5E-73 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 281 4.6E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 Gene3D G3DSA:3.50.50.60 3 83 3.5E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 Gene3D G3DSA:3.30.390.30 302 361 6.7E-5 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 SUPERFAMILY SSF51905 28 290 3.35E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 SUPERFAMILY SSF55424 294 360 3.85E-6 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 259 8.5E-16 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 79 97 8.5E-16 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 8.5E-16 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 222 8.5E-16 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 Gene3D G3DSA:3.50.50.60 84 289 1.2E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 122 147 1.6E-15 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 82 91 1.6E-15 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 207 221 1.6E-15 T 09-03-2017 ARZXY2_RS07190 876185fba726d0ce883155c0dea8dfb5 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 259 1.6E-15 T 09-03-2017 ARZXY2_RS00100 f3fd7a02c8dff94d89039f178e99716b 411 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 213 273 5.4E-8 T 09-03-2017 ARZXY2_RS00100 f3fd7a02c8dff94d89039f178e99716b 411 Gene3D G3DSA:2.130.10.130 199 274 2.9E-9 T 09-03-2017 ARZXY2_RS00100 f3fd7a02c8dff94d89039f178e99716b 411 SUPERFAMILY SSF69318 183 394 9.42E-23 T 09-03-2017 ARZXY2_RS03095 862f1b0e29c121fc4f733bdf58f3caf7 429 Pfam PF09594 Protein of unknown function (DUF2029) 69 318 6.5E-48 T 09-03-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 ARZXY2_RS12715 22fda6eccb5e801fc99bb761bb32d94a 545 Gene3D G3DSA:3.40.50.720 32 262 8.1E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12715 22fda6eccb5e801fc99bb761bb32d94a 545 Pfam PF11066 Protein of unknown function (DUF2867) 369 513 1.4E-33 T 09-03-2017 IPR021295 Protein of unknown function DUF2867 ARZXY2_RS12715 22fda6eccb5e801fc99bb761bb32d94a 545 SUPERFAMILY SSF55961 381 518 5.5E-8 T 09-03-2017 ARZXY2_RS12715 22fda6eccb5e801fc99bb761bb32d94a 545 Pfam PF13460 NAD(P)H-binding 50 159 3.4E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12715 22fda6eccb5e801fc99bb761bb32d94a 545 SUPERFAMILY SSF51735 42 275 3.34E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05650 ef0a782e330167f2c453dcc658ad09f6 251 ProSitePatterns PS00211 ABC transporters family signature. 179 193 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS05650 ef0a782e330167f2c453dcc658ad09f6 251 Pfam PF00005 ABC transporter 60 207 5.4E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05650 ef0a782e330167f2c453dcc658ad09f6 251 Gene3D G3DSA:3.40.50.300 37 248 2.6E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05650 ef0a782e330167f2c453dcc658ad09f6 251 SMART SM00382 68 244 2.6E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05650 ef0a782e330167f2c453dcc658ad09f6 251 SUPERFAMILY SSF52540 37 243 2.08E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06735 9949b7c9e61d38b823465ceeb2bd06a4 314 SUPERFAMILY SSF56349 108 293 4.71E-29 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06735 9949b7c9e61d38b823465ceeb2bd06a4 314 Pfam PF00589 Phage integrase family 111 291 1.5E-22 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06735 9949b7c9e61d38b823465ceeb2bd06a4 314 Gene3D G3DSA:1.10.443.10 103 297 2.3E-32 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 SMART SM00382 315 486 1.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 SMART SM00382 29 207 8.1E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 SUPERFAMILY SSF52540 9 199 1.05E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 Gene3D G3DSA:3.40.50.300 284 490 5.9E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 Gene3D G3DSA:3.40.50.300 8 223 4.9E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 SUPERFAMILY SSF52540 275 489 2.59E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 Pfam PF00005 ABC transporter 20 151 6.1E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS12795 19538e1c525c0ad2048e200f78841fcb 609 Pfam PF00005 ABC transporter 307 442 1.5E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS16350 65c69c06552f9e3b93151faf5bc04c9e 358 SUPERFAMILY SSF52096 250 326 1.58E-64 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS16350 65c69c06552f9e3b93151faf5bc04c9e 358 SUPERFAMILY SSF52096 11 195 1.58E-64 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS16350 65c69c06552f9e3b93151faf5bc04c9e 358 Gene3D G3DSA:3.90.226.10 10 205 1.5E-55 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS16350 65c69c06552f9e3b93151faf5bc04c9e 358 Pfam PF16113 Enoyl-CoA hydratase/isomerase 23 340 7.1E-123 T 09-03-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 ARZXY2_RS16350 65c69c06552f9e3b93151faf5bc04c9e 358 Gene3D G3DSA:1.10.12.10 267 324 1.1E-7 T 09-03-2017 IPR014748 Crontonase, C-terminal ARZXY2_RS07550 970d4e3a8c6340c23a84589e40d117e7 159 Pfam PF02566 OsmC-like protein 53 145 6.4E-16 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS07550 970d4e3a8c6340c23a84589e40d117e7 159 Gene3D G3DSA:3.30.300.20 4 153 7.8E-59 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS07550 970d4e3a8c6340c23a84589e40d117e7 159 SUPERFAMILY SSF82784 5 152 4.32E-46 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS04495 338c422a138c037025a235396987e2c5 359 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 19 351 3.8E-156 T 09-03-2017 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative ARZXY2_RS04495 338c422a138c037025a235396987e2c5 359 Pfam PF00296 Luciferase-like monooxygenase 37 320 3.0E-46 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS04495 338c422a138c037025a235396987e2c5 359 SUPERFAMILY SSF51679 35 352 2.83E-74 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS04495 338c422a138c037025a235396987e2c5 359 Gene3D G3DSA:3.20.20.30 16 355 2.6E-85 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS12700 d54728accd4da35c1ee828ec8b3ed6ba 240 Pfam PF00535 Glycosyl transferase family 2 10 174 2.7E-16 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS12700 d54728accd4da35c1ee828ec8b3ed6ba 240 SUPERFAMILY SSF53448 10 219 5.22E-28 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS12700 d54728accd4da35c1ee828ec8b3ed6ba 240 Gene3D G3DSA:3.90.550.10 9 210 3.6E-16 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS19095 7662a6ff448e312bbbb9815f8fc4e40a 250 SUPERFAMILY SSF51621 6 247 2.98E-54 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS19095 7662a6ff448e312bbbb9815f8fc4e40a 250 Gene3D G3DSA:3.20.20.60 6 246 2.3E-49 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS19095 7662a6ff448e312bbbb9815f8fc4e40a 250 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 21 212 1.0E-26 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 296 37.339 T 09-03-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 SUPERFAMILY SSF52374 5 261 1.13E-74 T 09-03-2017 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 Gene3D G3DSA:3.40.50.620 5 66 7.8E-39 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 Gene3D G3DSA:3.40.50.620 177 226 7.8E-39 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 1.1E-16 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 1.1E-16 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 175 185 1.1E-16 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 1.1E-16 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 199 1.1E-16 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 245 7.5E-48 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 4 257 5.2E-92 T 09-03-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 ARZXY2_RS20420 7e9402c5197ad9de6fbabfde29b7eb66 300 Gene3D G3DSA:3.90.800.10 67 174 3.3E-22 T 09-03-2017 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 1.6E-21 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Gene3D G3DSA:2.60.40.10 5 151 3.6E-58 T 09-03-2017 IPR013783 Immunoglobulin-like fold ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 698 0.0 T 09-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Pfam PF00128 Alpha amylase, catalytic domain 189 293 2.7E-9 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Pfam PF00128 Alpha amylase, catalytic domain 297 531 7.5E-6 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Gene3D G3DSA:3.20.20.80 152 574 4.1E-122 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 Gene3D G3DSA:2.60.40.1180 590 699 1.3E-21 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 SUPERFAMILY SSF51445 133 471 7.68E-133 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 SUPERFAMILY SSF51445 500 574 7.68E-133 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 SMART SM00642 166 566 2.9E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 SUPERFAMILY SSF51011 591 699 3.67E-17 T 09-03-2017 ARZXY2_RS03770 000d6e4a059d626973e43460591e2067 770 SUPERFAMILY SSF81296 5 147 5.32E-48 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS08420 d3ce0c6cb85d3321b1ed4dc6157429e6 178 Gene3D G3DSA:1.20.120.80 1 177 9.0E-45 T 09-03-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08420 d3ce0c6cb85d3321b1ed4dc6157429e6 178 SUPERFAMILY SSF81452 1 177 6.67E-45 T 09-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS08420 d3ce0c6cb85d3321b1ed4dc6157429e6 178 Pfam PF00510 Cytochrome c oxidase subunit III 1 176 2.7E-17 T 09-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.0E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.0E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.0E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 SUPERFAMILY SSF51735 7 253 3.71E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.4E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 Gene3D G3DSA:3.40.50.720 6 253 2.2E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13800 e9a661ef1047776afdf84c46fefc9f63 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 3.2E-62 T 09-03-2017 ARZXY2_RS20085 aeafebf20be4c6f4da471f92b7e76b6d 189 SUPERFAMILY SSF52218 5 178 7.54E-37 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS20085 aeafebf20be4c6f4da471f92b7e76b6d 189 Gene3D G3DSA:3.40.50.360 1 179 1.2E-39 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS20085 aeafebf20be4c6f4da471f92b7e76b6d 189 Pfam PF03358 NADPH-dependent FMN reductase 5 150 3.1E-32 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 758 784 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 579 599 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 201 217 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 621 650 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 150 163 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 259 274 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 414 434 1.2E-60 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 151 162 - T 09-03-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 Gene3D G3DSA:1.20.1440.90 290 417 1.1E-19 T 09-03-2017 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 932 18.403 T 09-03-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 Pfam PF00311 Phosphoenolpyruvate carboxylase 145 932 6.3E-290 T 09-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 ARZXY2_RS15370 a676eed7010c9fae05556c4eb1c3c92e 932 SUPERFAMILY SSF51621 17 932 5.34E-276 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 SUPERFAMILY SSF51735 1 335 1.67E-92 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 333 1.6E-133 T 09-03-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 Gene3D G3DSA:3.40.50.720 1 178 9.5E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 261 9.7E-58 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 Gene3D G3DSA:3.90.25.10 179 231 5.0E-48 T 09-03-2017 ARZXY2_RS04265 d52600060e983c65e6a0443a27457239 345 Gene3D G3DSA:3.90.25.10 263 336 5.0E-48 T 09-03-2017 ARZXY2_RS13110 ecf806f77ab8a53281b607e3dd92782a 317 Gene3D G3DSA:3.30.420.150 132 312 7.9E-57 T 09-03-2017 ARZXY2_RS13110 ecf806f77ab8a53281b607e3dd92782a 317 Pfam PF02541 Ppx/GppA phosphatase family 21 310 2.9E-59 T 09-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 ARZXY2_RS13110 ecf806f77ab8a53281b607e3dd92782a 317 SUPERFAMILY SSF53067 132 313 2.49E-36 T 09-03-2017 ARZXY2_RS13110 ecf806f77ab8a53281b607e3dd92782a 317 Gene3D G3DSA:3.30.420.40 1 125 3.9E-48 T 09-03-2017 ARZXY2_RS13110 ecf806f77ab8a53281b607e3dd92782a 317 SUPERFAMILY SSF53067 3 128 8.06E-34 T 09-03-2017 ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 SUPERFAMILY SSF51230 3 127 5.91E-41 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 Pfam PF01597 Glycine cleavage H-protein 8 126 8.3E-44 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 128 29.375 T 09-03-2017 IPR002930 Glycine cleavage system H-protein ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 Gene3D G3DSA:2.40.50.100 7 126 2.5E-47 T 09-03-2017 ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 50 79 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS10995 8383033df54fcf07c9649cbfdc0c5edd 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 2.0E-47 T 09-03-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 ARZXY2_RS08875 0a5f1c993c2dc000abc3519ff194b3be 376 SUPERFAMILY SSF55681 120 372 2.24E-65 T 09-03-2017 ARZXY2_RS08875 0a5f1c993c2dc000abc3519ff194b3be 376 Pfam PF03099 Biotin/lipoate A/B protein ligase family 186 290 6.7E-8 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ARZXY2_RS08875 0a5f1c993c2dc000abc3519ff194b3be 376 Gene3D G3DSA:3.90.1550.10 119 372 9.4E-67 T 09-03-2017 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 Gene3D G3DSA:3.40.309.10 266 445 4.8E-69 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 Gene3D G3DSA:3.40.605.10 7 265 9.0E-97 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 Pfam PF00171 Aldehyde dehydrogenase family 15 479 4.0E-171 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 SUPERFAMILY SSF53720 6 484 2.23E-166 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14995 3d4f23d3a6481ff7d64a0fc7087465d3 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS01670 13409444e9b2d1503d2ba2b43dbedf39 338 Pfam PF06089 L-asparaginase II 19 328 1.6E-104 T 09-03-2017 IPR010349 L-asparaginase II ARZXY2_RS11715 c68d85ba0463f5fbfcd672fba421c39e 284 Gene3D G3DSA:3.40.50.720 1 280 1.4E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11715 c68d85ba0463f5fbfcd672fba421c39e 284 SUPERFAMILY SSF51735 1 280 5.07E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11715 c68d85ba0463f5fbfcd672fba421c39e 284 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 9.2E-22 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 Pfam PF02733 Dak1 domain 18 325 1.1E-106 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 Pfam PF02734 DAK2 domain 392 565 7.4E-44 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 Gene3D G3DSA:3.30.1180.20 183 330 2.9E-44 T 09-03-2017 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 SUPERFAMILY SSF101473 367 565 2.75E-42 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 SMART SM01120 391 567 3.0E-57 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 Gene3D G3DSA:3.40.50.10440 13 181 3.6E-59 T 09-03-2017 ARZXY2_RS18870 0bc54cf176ae91b6dab3caeec2dcf97f 579 SUPERFAMILY SSF82549 11 329 3.4E-105 T 09-03-2017 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 Pfam PF00342 Phosphoglucose isomerase 79 230 4.7E-5 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 SUPERFAMILY SSF53697 11 382 2.45E-68 T 09-03-2017 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 Gene3D G3DSA:3.40.50.10490 189 291 7.5E-29 T 09-03-2017 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 Gene3D G3DSA:3.40.50.10490 442 522 7.0E-15 T 09-03-2017 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 187 205 3.1E-6 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 260 281 3.1E-6 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 83 102 3.1E-6 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 Gene3D G3DSA:3.40.50.10490 331 371 4.6E-9 T 09-03-2017 ARZXY2_RS09040 8d654cbe321b2b7b426c7ea76bd64ba6 543 Gene3D G3DSA:3.40.50.10490 78 188 4.9E-19 T 09-03-2017 ARZXY2_RS12905 d07b6845699eb25203cd62bfbe93279d 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 99 18.818 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS12905 d07b6845699eb25203cd62bfbe93279d 100 Pfam PF02467 Transcription factor WhiB 32 95 1.1E-26 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 70 83 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 SMART SM00062 48 263 1.5E-43 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 262 4.2E-51 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 Gene3D G3DSA:3.40.190.10 223 262 1.4E-32 T 09-03-2017 ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 Gene3D G3DSA:3.40.190.10 46 124 1.4E-32 T 09-03-2017 ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 Gene3D G3DSA:3.40.190.10 125 222 5.0E-20 T 09-03-2017 ARZXY2_RS02800 e84af2ba3075620a3bf1fe3e3c6bda9c 265 SUPERFAMILY SSF53850 15 262 9.42E-56 T 09-03-2017 ARZXY2_RS19070 0b11c3b66500196049f51fc6a75bc339 344 Gene3D G3DSA:3.20.20.30 12 342 8.5E-61 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS19070 0b11c3b66500196049f51fc6a75bc339 344 SUPERFAMILY SSF51679 14 333 1.44E-54 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS19070 0b11c3b66500196049f51fc6a75bc339 344 Pfam PF00296 Luciferase-like monooxygenase 27 298 3.0E-33 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS19300 ea052392bf0d1c4af3a850b82ca3caa1 110 Gene3D G3DSA:1.10.260.40 33 76 3.4E-4 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS19300 ea052392bf0d1c4af3a850b82ca3caa1 110 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 77 2.7E-17 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 SUPERFAMILY SSF51735 103 224 2.89E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 SMART SM00881 99 200 6.7E-16 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 Gene3D G3DSA:1.10.10.10 24 95 3.7E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 SUPERFAMILY SSF46785 27 98 3.95E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 21 229 33.557 T 09-03-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 Pfam PF02629 CoA binding domain 102 199 2.6E-18 T 09-03-2017 IPR003781 CoA-binding GO:0048037 ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 Pfam PF06971 Putative DNA-binding protein N-terminus 25 73 3.3E-17 T 09-03-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 ARZXY2_RS02125 c1ba5a91692f44581dfffc8143704296 235 Gene3D G3DSA:3.40.50.720 98 229 2.9E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 6.0E-235 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 SUPERFAMILY SSF52016 426 614 4.32E-60 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 SUPERFAMILY SSF143975 4 425 5.36E-127 T 09-03-2017 ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 44.299 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS16030 e54578e7f3d14306d5fe1d696ffc65a5 620 Pfam PF00920 Dehydratase family 34 610 3.6E-210 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 Pfam PF00717 Peptidase S24-like 39 77 1.0E-8 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 111 123 9.4E-19 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 159 178 9.4E-19 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 33 49 9.4E-19 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 Gene3D G3DSA:2.10.109.10 159 211 1.3E-35 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 Gene3D G3DSA:2.10.109.10 29 121 1.3E-35 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 Pfam PF10502 Signal peptidase, peptidase S26 103 179 5.0E-7 T 09-03-2017 IPR019533 Peptidase S26 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 18 206 1.5E-36 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 SUPERFAMILY SSF51306 106 210 3.19E-45 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS07030 23e04950192db35a174207c810c142f1 224 SUPERFAMILY SSF51306 31 79 3.19E-45 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C ARZXY2_RS18715 22aef11c9f5f5aa1c4314e01566b2b89 234 SMART SM00014 96 199 5.7E-13 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18715 22aef11c9f5f5aa1c4314e01566b2b89 234 Gene3D G3DSA:1.20.144.10 57 199 9.8E-26 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18715 22aef11c9f5f5aa1c4314e01566b2b89 234 Pfam PF01569 PAP2 superfamily 100 199 3.0E-15 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS18715 22aef11c9f5f5aa1c4314e01566b2b89 234 SUPERFAMILY SSF48317 27 202 3.14E-31 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 Pfam PF00293 NUDIX domain 9 131 2.6E-12 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 SUPERFAMILY SSF55811 6 138 2.44E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 Gene3D G3DSA:3.90.79.10 6 152 3.9E-34 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 24 40 1.0E-6 T 09-03-2017 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 88 107 1.0E-6 T 09-03-2017 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 ARZXY2_RS11095 fc8146f7cd6d861cb430ace9fc46fbe6 163 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 108 126 1.0E-6 T 09-03-2017 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 ARZXY2_RS18460 064f87b2e199d9c95b32d2155566288e 84 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 83 2.4E-31 T 09-03-2017 IPR009619 Cell division protein CrgA ARZXY2_RS18460 064f87b2e199d9c95b32d2155566288e 84 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 83 25.381 T 09-03-2017 IPR009619 Cell division protein CrgA ARZXY2_RS15350 f8c3c36dd4fb3c9c9e28eb221cca0e08 309 Pfam PF00849 RNA pseudouridylate synthase 96 252 3.5E-23 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS15350 f8c3c36dd4fb3c9c9e28eb221cca0e08 309 SUPERFAMILY SSF55120 88 302 1.6E-46 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 ARZXY2_RS18485 7f464b2a0411bad8265a5a1c9d1fd84b 200 Pfam PF03352 Methyladenine glycosylase 20 191 3.3E-68 T 09-03-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 ARZXY2_RS18485 7f464b2a0411bad8265a5a1c9d1fd84b 200 SUPERFAMILY SSF48150 16 193 5.61E-68 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS18485 7f464b2a0411bad8265a5a1c9d1fd84b 200 Gene3D G3DSA:1.10.340.30 16 193 1.4E-74 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 ARZXY2_RS05025 37256ec96e7649c1afe3cada44179f00 171 Pfam PF07681 DoxX 5 88 8.1E-13 T 09-03-2017 IPR032808 DoxX family ARZXY2_RS20425 987e504cb5cdb41aaef70065b9e433c2 384 Gene3D G3DSA:3.40.710.10 8 377 5.2E-52 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS20425 987e504cb5cdb41aaef70065b9e433c2 384 SUPERFAMILY SSF56601 7 367 4.83E-49 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS20425 987e504cb5cdb41aaef70065b9e433c2 384 Pfam PF00144 Beta-lactamase 20 364 1.1E-49 T 09-03-2017 IPR001466 Beta-lactamase-related ARZXY2_RS18430 4fdde64a7b3e164b246db084ffff95e6 476 Pfam PF01098 Cell cycle protein 76 435 1.7E-71 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 Gene3D G3DSA:3.30.450.40 224 355 1.1E-5 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 SMART SM00065 51 198 7.2E-19 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 Pfam PF13185 GAF domain 50 189 1.5E-15 T 09-03-2017 IPR003018 GAF domain GO:0005515 ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 Pfam PF07730 Histidine kinase 369 430 3.2E-11 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 SUPERFAMILY SSF55781 199 356 3.92E-6 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 SUPERFAMILY SSF55781 33 214 3.27E-37 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS09885 bde8c9d38acfc4ae81d76057698b9845 437 Gene3D G3DSA:3.30.450.40 32 196 2.2E-30 T 09-03-2017 IPR029016 GAF domain-like ARZXY2_RS17570 adeb1d66db46094fd04cb8f87af0e555 226 Pfam PF01730 UreF 40 183 7.6E-30 T 09-03-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 ARZXY2_RS17570 adeb1d66db46094fd04cb8f87af0e555 226 Hamap MF_01385 Urease accessory protein UreF [ureF]. 8 226 28.227 T 09-03-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 ARZXY2_RS17570 adeb1d66db46094fd04cb8f87af0e555 226 PIRSF PIRSF009467 6 226 8.9E-68 T 09-03-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 ARZXY2_RS11755 aa07098d88442d1b0d75326c4c351d1a 126 Pfam PF04341 Protein of unknown function, DUF485 20 106 9.8E-33 T 09-03-2017 IPR007436 Protein of unknown function DUF485 ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 SMART SM00895 100 221 6.9E-12 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 Pfam PF07729 FCD domain 100 220 3.9E-16 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 SMART SM00345 32 90 1.2E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 SUPERFAMILY SSF46785 27 107 1.84E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 Gene3D G3DSA:1.20.120.530 95 229 5.5E-31 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 SUPERFAMILY SSF48008 96 225 1.07E-23 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 Gene3D G3DSA:1.10.10.10 27 91 2.2E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18340 33783ac7f23c411100e33f4f0b3bbf60 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 90 2.3E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS10290 47b5f1053aea86b50a59e613a8097b6c 138 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 53 125 1.2E-33 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ARZXY2_RS10290 47b5f1053aea86b50a59e613a8097b6c 138 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 27 130 30.545 T 09-03-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ARZXY2_RS10290 47b5f1053aea86b50a59e613a8097b6c 138 SUPERFAMILY SSF141734 27 128 1.83E-45 T 09-03-2017 ARZXY2_RS10290 47b5f1053aea86b50a59e613a8097b6c 138 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 76 125 7.0E-23 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 ARZXY2_RS12320 7ba9069e5c7b98614ce8471ccb4e1f4c 542 SUPERFAMILY SSF53850 99 534 6.61E-43 T 09-03-2017 ARZXY2_RS12320 7ba9069e5c7b98614ce8471ccb4e1f4c 542 Gene3D G3DSA:3.40.190.10 239 401 8.1E-21 T 09-03-2017 ARZXY2_RS12320 7ba9069e5c7b98614ce8471ccb4e1f4c 542 Gene3D G3DSA:3.40.190.10 485 534 8.1E-21 T 09-03-2017 ARZXY2_RS12320 7ba9069e5c7b98614ce8471ccb4e1f4c 542 Gene3D G3DSA:3.40.190.10 103 238 3.4E-14 T 09-03-2017 ARZXY2_RS05895 78dd162abe5b1729826a8d56052b7bae 92 SUPERFAMILY SSF46689 2 77 8.51E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS05895 78dd162abe5b1729826a8d56052b7bae 92 Pfam PF01527 Transposase 3 75 1.6E-10 T 09-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS05895 78dd162abe5b1729826a8d56052b7bae 92 Gene3D G3DSA:1.10.10.60 20 89 1.0E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 Gene3D G3DSA:3.50.50.60 2 108 2.8E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 7.5E-12 T 09-03-2017 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.5E-12 T 09-03-2017 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 7.5E-12 T 09-03-2017 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 7.5E-12 T 09-03-2017 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 Pfam PF04324 BFD-like [2Fe-2S] binding domain 465 513 2.1E-12 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 291 2.3E-41 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 SUPERFAMILY SSF51905 3 198 1.94E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 SUPERFAMILY SSF51905 154 325 1.79E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12545 6e7b5c61c1153b6588f83c23a00ea52d 521 Gene3D G3DSA:3.50.50.60 109 326 2.1E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 Gene3D G3DSA:1.10.3860.10 23 438 2.6E-95 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 SUPERFAMILY SSF118215 26 436 1.15E-92 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 Pfam PF00375 Sodium:dicarboxylate symporter family 27 435 3.4E-107 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 180 202 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 329 355 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 390 410 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 364 383 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 100 125 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 227 246 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS12495 57199dde24e213c2b7f8df3bf8e2f497 477 PRINTS PR00173 Glutamate-aspartate symporter signature 70 90 5.0E-30 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 Gene3D G3DSA:2.30.38.10 398 461 2.1E-19 T 09-03-2017 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 SUPERFAMILY SSF56801 338 598 3.79E-109 T 09-03-2017 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 SUPERFAMILY SSF56801 17 290 3.79E-109 T 09-03-2017 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 Gene3D G3DSA:3.40.50.980 16 192 5.2E-29 T 09-03-2017 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 Pfam PF00501 AMP-binding enzyme 31 467 3.0E-91 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 Gene3D G3DSA:3.40.50.980 193 285 1.1E-28 T 09-03-2017 ARZXY2_RS10960 7123cbcc4df3902760ed3541c7b95431 603 Gene3D G3DSA:3.40.50.980 335 397 1.1E-28 T 09-03-2017 ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 Hamap MF_01974 Methionine aminopeptidase [map]. 45 292 40.324 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 132 148 9.0E-23 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 110 123 9.0E-23 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 214 9.0E-23 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 234 246 9.0E-23 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 208 226 - T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 Gene3D G3DSA:3.90.230.10 47 291 2.5E-95 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 Pfam PF00557 Metallopeptidase family M24 54 283 3.1E-52 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 SUPERFAMILY SSF55920 9 291 7.98E-87 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS10760 8db0068f4e578b612335d7b432565ce8 292 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 46 290 7.2E-92 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS12580 614b28de226613ed689e2b93832a6e0f 120 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 16 119 2.9E-28 T 09-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 ARZXY2_RS12580 614b28de226613ed689e2b93832a6e0f 120 SUPERFAMILY SSF50022 16 120 2.31E-32 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS12580 614b28de226613ed689e2b93832a6e0f 120 Pfam PF13806 Rieske-like [2Fe-2S] domain 16 119 5.6E-34 T 09-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 ARZXY2_RS12580 614b28de226613ed689e2b93832a6e0f 120 Gene3D G3DSA:2.102.10.10 15 120 5.0E-36 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS20305 affa2fcbf9f1e01552bc6fab99151303 202 SUPERFAMILY SSF46689 29 97 1.55E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20305 affa2fcbf9f1e01552bc6fab99151303 202 Gene3D G3DSA:1.10.357.10 27 182 1.2E-19 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS20305 affa2fcbf9f1e01552bc6fab99151303 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 82 2.9E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS08635 bc3aea316587b2510706aa00521b0b7f 308 Gene3D G3DSA:3.10.50.40 68 143 9.2E-4 T 09-03-2017 ARZXY2_RS08635 bc3aea316587b2510706aa00521b0b7f 308 SUPERFAMILY SSF54534 205 308 2.36E-30 T 09-03-2017 ARZXY2_RS08635 bc3aea316587b2510706aa00521b0b7f 308 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 219 304 1.6E-17 T 09-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 ARZXY2_RS08635 bc3aea316587b2510706aa00521b0b7f 308 SUPERFAMILY SSF54534 65 146 2.48E-5 T 09-03-2017 ARZXY2_RS08635 bc3aea316587b2510706aa00521b0b7f 308 Gene3D G3DSA:3.10.50.40 202 307 4.7E-30 T 09-03-2017 ARZXY2_RS08015 34e1ddd288d06b9595ecf205a2cebe90 247 Gene3D G3DSA:2.40.100.10 88 244 1.9E-23 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS08015 34e1ddd288d06b9595ecf205a2cebe90 247 SUPERFAMILY SSF50891 87 244 1.03E-24 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS08015 34e1ddd288d06b9595ecf205a2cebe90 247 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 91 243 1.2E-20 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 268 281 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 SUPERFAMILY SSF53613 19 320 4.21E-76 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 Gene3D G3DSA:3.40.1190.20 19 321 2.7E-82 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 Pfam PF00294 pfkB family carbohydrate kinase 19 314 3.3E-54 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 PRINTS PR00990 Ribokinase signature 199 214 3.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 PRINTS PR00990 Ribokinase signature 45 64 3.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS19185 f15a20cb6e4d7c0a5de22a26accdb9da 331 PRINTS PR00990 Ribokinase signature 239 250 3.0E-5 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS02105 80f7b38da98dc07d8292157501b496f1 70 SUPERFAMILY SSF46955 11 58 3.3E-6 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS02105 80f7b38da98dc07d8292157501b496f1 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 59 2.6E-21 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS02105 80f7b38da98dc07d8292157501b496f1 70 Pfam PF12728 Helix-turn-helix domain 12 60 2.1E-15 T 09-03-2017 ARZXY2_RS02105 80f7b38da98dc07d8292157501b496f1 70 Gene3D G3DSA:1.10.10.10 12 66 4.8E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02355 1a06b8f9bcdcc0bf1a4ccc4e3abccc8d 270 Gene3D G3DSA:3.40.50.150 39 189 7.3E-17 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS02355 1a06b8f9bcdcc0bf1a4ccc4e3abccc8d 270 Pfam PF13649 Methyltransferase domain 72 168 1.2E-8 T 09-03-2017 ARZXY2_RS02355 1a06b8f9bcdcc0bf1a4ccc4e3abccc8d 270 SUPERFAMILY SSF53335 26 183 7.38E-17 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS07440 a7d0e20f47d26762ee843144d4ae5fb3 303 Gene3D G3DSA:3.40.1390.30 27 138 3.0E-41 T 09-03-2017 ARZXY2_RS07440 a7d0e20f47d26762ee843144d4ae5fb3 303 SUPERFAMILY SSF102705 27 296 7.85E-80 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ARZXY2_RS07440 a7d0e20f47d26762ee843144d4ae5fb3 303 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 30 292 3.9E-49 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ARZXY2_RS07440 a7d0e20f47d26762ee843144d4ae5fb3 303 Gene3D G3DSA:3.40.1390.30 139 244 3.8E-33 T 09-03-2017 ARZXY2_RS07440 a7d0e20f47d26762ee843144d4ae5fb3 303 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 31 273 9.6E-68 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ARZXY2_RS03690 83af6e36c663643908d461ac827b9424 313 Pfam PF00482 Type II secretion system (T2SS), protein F 146 270 1.0E-18 T 09-03-2017 IPR018076 Type II secretion system F domain ARZXY2_RS16440 7862e1141d593486568a80586cf71f82 342 Gene3D G3DSA:3.40.50.720 139 294 9.3E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16440 7862e1141d593486568a80586cf71f82 342 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 312 6.5E-102 T 09-03-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 ARZXY2_RS16440 7862e1141d593486568a80586cf71f82 342 Gene3D G3DSA:3.30.1780.10 2 138 4.0E-40 T 09-03-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 ARZXY2_RS16440 7862e1141d593486568a80586cf71f82 342 SUPERFAMILY SSF51735 2 335 3.04E-95 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13465 f12452fbefbfe2c3cec2fbafd305943c 419 SUPERFAMILY SSF159941 10 191 1.03E-40 T 09-03-2017 IPR024047 Protein MM3350-like domain ARZXY2_RS13465 f12452fbefbfe2c3cec2fbafd305943c 419 Gene3D G3DSA:3.10.290.30 6 191 5.9E-43 T 09-03-2017 IPR024047 Protein MM3350-like domain ARZXY2_RS13465 f12452fbefbfe2c3cec2fbafd305943c 419 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 8 188 1.6E-44 T 09-03-2017 IPR012912 Plasmid pRiA4b, Orf3 ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 8 168 2.3E-69 T 09-03-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 Gene3D G3DSA:1.10.3130.10 4 64 8.9E-22 T 09-03-2017 ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 SUPERFAMILY SSF51161 3 169 2.08E-52 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 PIRSF PIRSF000441 1 189 3.3E-78 T 09-03-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 Gene3D G3DSA:2.160.10.10 65 174 4.3E-34 T 09-03-2017 ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 111 4.1E-5 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS07425 e3f8f2935a766d0f4066922ac8e26003 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 153 3.4E-8 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS01825 8bee4610b00195f55387f252ac2270f4 341 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 5 334 6.3E-89 T 09-03-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like ARZXY2_RS01825 8bee4610b00195f55387f252ac2270f4 341 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 114 263 3.7E-5 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain ARZXY2_RS01825 8bee4610b00195f55387f252ac2270f4 341 Gene3D G3DSA:3.40.50.300 111 318 4.9E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01825 8bee4610b00195f55387f252ac2270f4 341 SUPERFAMILY SSF52540 112 319 1.13E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04105 53df28ffd41fef0c91e5ad1a01ac4e64 320 Gene3D G3DSA:3.40.190.120 157 256 3.1E-31 T 09-03-2017 ARZXY2_RS04105 53df28ffd41fef0c91e5ad1a01ac4e64 320 SUPERFAMILY SSF53850 53 318 1.03E-50 T 09-03-2017 ARZXY2_RS04105 53df28ffd41fef0c91e5ad1a01ac4e64 320 Gene3D G3DSA:3.40.190.10 268 319 5.7E-43 T 09-03-2017 ARZXY2_RS04105 53df28ffd41fef0c91e5ad1a01ac4e64 320 Gene3D G3DSA:3.40.190.10 50 156 5.7E-43 T 09-03-2017 ARZXY2_RS04105 53df28ffd41fef0c91e5ad1a01ac4e64 320 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 53 314 2.6E-51 T 09-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 ARZXY2_RS19075 a813c5b85113fc41d1699989cc3ddfc3 313 Gene3D G3DSA:3.40.830.10 4 187 2.7E-70 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS19075 a813c5b85113fc41d1699989cc3ddfc3 313 Gene3D G3DSA:3.40.830.10 230 308 2.7E-70 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS19075 a813c5b85113fc41d1699989cc3ddfc3 313 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 6 303 1.9E-45 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS19075 a813c5b85113fc41d1699989cc3ddfc3 313 SUPERFAMILY SSF53213 5 185 1.19E-60 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS19075 a813c5b85113fc41d1699989cc3ddfc3 313 SUPERFAMILY SSF53213 228 306 1.19E-60 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS02600 8dc9b8cd51e8d7bfcfe73109a51f505b 296 Pfam PF01061 ABC-2 type transporter 61 256 4.0E-15 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS01155 3fae79b2b80b8f8e839632b11c339b18 364 Gene3D G3DSA:3.40.640.10 21 256 4.4E-47 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS01155 3fae79b2b80b8f8e839632b11c339b18 364 Gene3D G3DSA:3.90.1150.10 257 363 6.1E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS01155 3fae79b2b80b8f8e839632b11c339b18 364 SUPERFAMILY SSF53383 8 362 4.03E-85 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS01155 3fae79b2b80b8f8e839632b11c339b18 364 Pfam PF00266 Aminotransferase class-V 33 327 9.2E-29 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS01155 3fae79b2b80b8f8e839632b11c339b18 364 PIRSF PIRSF000524 1 364 1.2E-100 T 09-03-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 ARZXY2_RS01805 7d05677eb6c1409806f2a679ca86a192 225 SUPERFAMILY SSF55811 64 202 2.98E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01805 7d05677eb6c1409806f2a679ca86a192 225 Pfam PF00293 NUDIX domain 64 131 4.8E-12 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS01805 7d05677eb6c1409806f2a679ca86a192 225 Gene3D G3DSA:3.90.79.10 32 207 5.7E-34 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 16 57 2.0E-14 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 16 69 1.0E-20 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 Pfam PF02609 Exonuclease VII small subunit 17 66 1.8E-17 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 16 76 13.231 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 SUPERFAMILY SSF116842 11 69 7.72E-17 T 09-03-2017 ARZXY2_RS04120 661d37bfb3e48cb40a9194ebd2bd9725 77 Gene3D G3DSA:1.10.287.1040 14 72 1.8E-22 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 Gene3D G3DSA:1.20.58.110 3 86 1.2E-28 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.666 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 Pfam PF01649 Ribosomal protein S20 2 84 1.0E-26 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 SUPERFAMILY SSF46992 3 86 8.11E-27 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 1.2E-23 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS08245 12895479405f9be968ef7b2e2a0ea42d 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 3.0E-17 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS01500 7c08a262216697655e173fed7406d55d 354 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 113 190 2.0E-8 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 ARZXY2_RS01500 7c08a262216697655e173fed7406d55d 354 Gene3D G3DSA:2.40.110.10 113 190 4.6E-11 T 09-03-2017 ARZXY2_RS01500 7c08a262216697655e173fed7406d55d 354 Gene3D G3DSA:1.20.140.10 198 305 7.9E-7 T 09-03-2017 ARZXY2_RS01500 7c08a262216697655e173fed7406d55d 354 SUPERFAMILY SSF56645 38 192 6.54E-16 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 ARZXY2_RS19115 2c3f2958c3ac8fbfdd98ff193827922a 257 Gene3D G3DSA:1.10.3720.10 50 243 6.3E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19115 2c3f2958c3ac8fbfdd98ff193827922a 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 242 6.9E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19115 2c3f2958c3ac8fbfdd98ff193827922a 257 SUPERFAMILY SSF161098 52 234 1.31E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PIRSF PIRSF001529 1 425 7.5E-136 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PRINTS PR00981 Seryl-tRNA synthetase signature 261 273 5.9E-31 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PRINTS PR00981 Seryl-tRNA synthetase signature 273 286 5.9E-31 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PRINTS PR00981 Seryl-tRNA synthetase signature 313 326 5.9E-31 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PRINTS PR00981 Seryl-tRNA synthetase signature 330 346 5.9E-31 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 PRINTS PR00981 Seryl-tRNA synthetase signature 348 364 5.9E-31 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 Gene3D G3DSA:1.10.287.40 2 103 5.2E-26 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.0E-24 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 SUPERFAMILY SSF55681 115 424 3.67E-79 T 09-03-2017 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 417 2.3E-131 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 37.845 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 Gene3D G3DSA:3.30.930.10 104 421 1.7E-115 T 09-03-2017 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 SUPERFAMILY SSF46589 2 111 1.31E-25 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 ARZXY2_RS18150 15a333822a42ee2e29bde062e112a674 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 400 9.5E-24 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS20595 ad6c1adcf822d825168a16b9669d14c2 95 SUPERFAMILY SSF54909 1 82 6.7E-13 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS20595 ad6c1adcf822d825168a16b9669d14c2 95 Pfam PF03795 YCII-related domain 1 81 2.9E-8 T 09-03-2017 IPR005545 YCII-related ARZXY2_RS20595 ad6c1adcf822d825168a16b9669d14c2 95 Gene3D G3DSA:3.30.70.1060 15 82 1.2E-4 T 09-03-2017 ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 137 2.1E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 Gene3D G3DSA:3.30.360.10 327 385 7.3E-31 T 09-03-2017 ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 Gene3D G3DSA:3.30.360.10 160 289 7.3E-31 T 09-03-2017 ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 Gene3D G3DSA:3.40.50.720 5 159 6.8E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 SUPERFAMILY SSF51735 8 167 9.03E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 SUPERFAMILY SSF55347 146 322 8.01E-32 T 09-03-2017 ARZXY2_RS16920 dabab79850df230fd1b271a36a11afa6 394 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 153 272 4.2E-6 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS03970 f26b8304c82ca1e95f46bbeca091d834 301 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 6.6E-104 T 09-03-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 ARZXY2_RS03970 f26b8304c82ca1e95f46bbeca091d834 301 SUPERFAMILY SSF53448 6 277 1.57E-63 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS03970 f26b8304c82ca1e95f46bbeca091d834 301 Pfam PF00483 Nucleotidyl transferase 10 273 2.3E-26 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ARZXY2_RS03970 f26b8304c82ca1e95f46bbeca091d834 301 Gene3D G3DSA:3.90.550.10 9 283 4.6E-72 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS05435 836c7c7a6f2dad43d327214d2ccf9388 119 Pfam PF02656 Domain of unknown function (DUF202) 10 87 1.6E-18 T 09-03-2017 IPR003807 Domain of unknown function DUF202 ARZXY2_RS05435 836c7c7a6f2dad43d327214d2ccf9388 119 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 9 32 9.0E-4 T 09-03-2017 IPR020264 Uncharacterised protein family YidG ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 232 4.2E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 152 4.2E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 251 4.2E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 268 288 4.2E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 82 4.2E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 64 244 0.0047 T 09-03-2017 ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 Gene3D G3DSA:3.40.50.720 59 303 1.0E-80 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 SUPERFAMILY SSF51735 62 303 2.31E-78 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19870 69234b7871c73b1a0775cf0d6d84c218 306 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 73 303 1.1E-58 T 09-03-2017 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 Gene3D G3DSA:3.30.190.20 19 69 2.7E-42 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 Gene3D G3DSA:3.30.190.20 160 227 2.7E-42 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 2.6E-51 T 09-03-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.8E-99 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.795 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 Gene3D G3DSA:3.40.50.790 70 159 8.8E-42 T 09-03-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 09-03-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 PIRSF PIRSF002155 1 227 6.3E-72 T 09-03-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03415 6cf0b98173ec744fbaf02b84dbf7dcac 235 SUPERFAMILY SSF56808 6 227 1.27E-80 T 09-03-2017 IPR023674 Ribosomal protein L1-like ARZXY2_RS18785 c217ae1c089f055bc476423f9017c4e2 195 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 128 5.7E-33 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS18785 c217ae1c089f055bc476423f9017c4e2 195 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 32.015 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS18785 c217ae1c089f055bc476423f9017c4e2 195 Pfam PF00436 Single-strand binding protein family 6 106 2.4E-31 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 ARZXY2_RS18785 c217ae1c089f055bc476423f9017c4e2 195 Gene3D G3DSA:2.40.50.140 3 118 5.0E-42 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS18785 c217ae1c089f055bc476423f9017c4e2 195 SUPERFAMILY SSF50249 6 195 7.83E-44 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 Gene3D G3DSA:3.90.470.10 1 115 9.7E-41 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 Pfam PF00237 Ribosomal protein L22p/L17e 8 112 1.3E-32 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 SUPERFAMILY SSF54843 1 114 5.36E-40 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 115 29.365 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 112 6.3E-41 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03520 c1d44935343577683e38fe62391bf9f6 121 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 09-03-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS06370 662128a270688e4d57e20f8bd3a41890 111 Pfam PF11774 Lsr2 7 104 8.4E-24 T 09-03-2017 IPR024412 Lsr2 ARZXY2_RS06370 662128a270688e4d57e20f8bd3a41890 111 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 6 105 8.0E-7 T 09-03-2017 IPR024412 Lsr2 ARZXY2_RS05090 72525d6b15c1b4d091f3fa56a24b18ad 223 SMART SM00849 7 185 1.3E-4 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05090 72525d6b15c1b4d091f3fa56a24b18ad 223 Gene3D G3DSA:3.60.15.10 1 57 5.7E-27 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05090 72525d6b15c1b4d091f3fa56a24b18ad 223 Gene3D G3DSA:3.60.15.10 92 222 5.7E-27 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05090 72525d6b15c1b4d091f3fa56a24b18ad 223 SUPERFAMILY SSF56281 4 188 2.1E-19 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS05090 72525d6b15c1b4d091f3fa56a24b18ad 223 Pfam PF13483 Beta-lactamase superfamily domain 2 185 5.0E-16 T 09-03-2017 ARZXY2_RS03345 7e19d41ca4824ee1a3477a1acd387557 209 Pfam PF03551 Transcriptional regulator PadR-like family 15 88 1.7E-12 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS03345 7e19d41ca4824ee1a3477a1acd387557 209 SUPERFAMILY SSF46785 15 182 5.45E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03345 7e19d41ca4824ee1a3477a1acd387557 209 Gene3D G3DSA:1.10.10.10 10 95 6.7E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00485 3860f1e3b8e4097f384fcd74a8586562 313 SUPERFAMILY SSF56752 15 312 7.98E-53 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ARZXY2_RS00485 3860f1e3b8e4097f384fcd74a8586562 313 Gene3D G3DSA:3.20.10.10 137 312 1.1E-32 T 09-03-2017 ARZXY2_RS00485 3860f1e3b8e4097f384fcd74a8586562 313 Gene3D G3DSA:3.30.470.10 18 124 1.3E-19 T 09-03-2017 ARZXY2_RS00485 3860f1e3b8e4097f384fcd74a8586562 313 Pfam PF01063 Amino-transferase class IV 41 287 8.3E-42 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 ARZXY2_RS02075 17071a603e942def838524ffb79346af 324 Gene3D G3DSA:1.10.3720.10 86 317 1.3E-44 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02075 17071a603e942def838524ffb79346af 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 318 7.9E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02075 17071a603e942def838524ffb79346af 324 SUPERFAMILY SSF161098 81 308 8.11E-47 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS07260 36af280ef76c94fc13b848d28391951c 147 SUPERFAMILY SSF50475 4 128 3.37E-20 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS07260 36af280ef76c94fc13b848d28391951c 147 Gene3D G3DSA:2.30.110.10 4 129 7.4E-19 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS07260 36af280ef76c94fc13b848d28391951c 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 93 4.6E-9 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 ARZXY2_RS08850 fb125874a6576aa7d21336e5ad3b98e3 483 Gene3D G3DSA:3.40.50.720 323 461 6.2E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08850 fb125874a6576aa7d21336e5ad3b98e3 483 Gene3D G3DSA:3.40.50.720 124 227 6.2E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08850 fb125874a6576aa7d21336e5ad3b98e3 483 SUPERFAMILY SSF51735 328 435 1.25E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08850 fb125874a6576aa7d21336e5ad3b98e3 483 SUPERFAMILY SSF51735 137 235 1.25E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08850 fb125874a6576aa7d21336e5ad3b98e3 483 Pfam PF00106 short chain dehydrogenase 143 230 1.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS12025 99c087f8628e02a99434a6a9b3cc3c2c 442 Gene3D G3DSA:3.40.50.1110 296 438 8.0E-12 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS12025 99c087f8628e02a99434a6a9b3cc3c2c 442 Gene3D G3DSA:3.40.50.1110 175 222 8.0E-12 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS12025 99c087f8628e02a99434a6a9b3cc3c2c 442 SUPERFAMILY SSF52266 302 433 6.72E-10 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 471 46.064 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 SUPERFAMILY SSF53271 264 476 1.7E-70 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 SUPERFAMILY SSF56235 23 281 5.4E-67 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 Pfam PF00156 Phosphoribosyl transferase domain 293 399 4.2E-10 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 Gene3D G3DSA:3.40.50.2020 284 451 8.7E-47 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 Pfam PF13537 Glutamine amidotransferase domain 104 227 3.4E-16 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 Gene3D G3DSA:3.60.20.10 23 270 6.5E-67 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 470 1.0E-157 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ARZXY2_RS01130 272cc848a31a1501f1975b11fa846acf 547 PIRSF PIRSF000485 19 483 3.1E-164 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 SUPERFAMILY SSF51735 12 264 1.55E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 Gene3D G3DSA:3.40.50.720 13 255 6.4E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 Pfam PF00106 short chain dehydrogenase 16 208 8.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS00805 65cee5dfc8bd46f12e48fa5de01b1382 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 Gene3D G3DSA:1.20.1250.20 18 205 3.9E-32 T 09-03-2017 ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 Pfam PF00083 Sugar (and other) transporter 64 449 6.0E-42 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 336 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 SUPERFAMILY SSF103473 14 449 1.57E-79 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13410 e4cde4be8fad01b4f172ac4a316fb219 450 Gene3D G3DSA:1.20.1250.20 266 449 2.1E-23 T 09-03-2017 ARZXY2_RS10025 0f8f8dba0a2c16caf91faa7592e83ac1 384 Pfam PF12698 ABC-2 family transporter protein 13 374 2.2E-27 T 09-03-2017 ARZXY2_RS19050 a2ddcccb4eb1b1ae4829f9e247320225 844 Gene3D G3DSA:1.25.40.10 445 581 8.8E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS19050 a2ddcccb4eb1b1ae4829f9e247320225 844 Pfam PF12770 CHAT domain 73 344 4.8E-25 T 09-03-2017 IPR024983 CHAT domain ARZXY2_RS19050 a2ddcccb4eb1b1ae4829f9e247320225 844 SUPERFAMILY SSF48452 444 493 6.88E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS18225 b9bf4f4c727bab7720ab9e779a516e33 163 Pfam PF11188 Protein of unknown function (DUF2975) 44 163 2.4E-22 T 09-03-2017 IPR021354 Protein of unknown function DUF2975 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 SUPERFAMILY SSF51246 330 445 9.94E-40 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 SMART SM00878 335 441 9.3E-55 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 SUPERFAMILY SSF52440 1 112 1.29E-44 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 3.2E-42 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Gene3D G3DSA:3.30.1490.20 129 201 2.7E-24 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 SUPERFAMILY SSF56059 82 348 2.83E-64 T 09-03-2017 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Gene3D G3DSA:3.40.50.20 1 128 2.1E-46 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 4.8E-38 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 316 2.3E-69 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS13745 e62bd83ae2d5b48f14bac2b08467c549 450 Gene3D G3DSA:3.30.470.20 202 445 3.6E-93 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 Gene3D G3DSA:2.60.40.1280 42 161 1.0E-21 T 09-03-2017 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 SUPERFAMILY SSF49401 40 160 2.24E-19 T 09-03-2017 IPR008966 Adhesion domain ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 PRINTS PR01217 Proline rich extensin signature 248 264 3.7E-11 T 09-03-2017 ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 PRINTS PR01217 Proline rich extensin signature 337 353 3.7E-11 T 09-03-2017 ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 PRINTS PR01217 Proline rich extensin signature 312 333 3.7E-11 T 09-03-2017 ARZXY2_RS15410 ed13e3b58a5ebbae4dead7d2d9db9fff 446 PRINTS PR01217 Proline rich extensin signature 355 372 3.7E-11 T 09-03-2017 ARZXY2_RS15515 0f626899e7af44ebaab755a768dbffbb 235 Gene3D G3DSA:3.30.530.20 5 116 8.6E-7 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS15515 0f626899e7af44ebaab755a768dbffbb 235 SUPERFAMILY SSF55961 5 116 1.46E-10 T 09-03-2017 ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 PRINTS PR00990 Ribokinase signature 38 57 3.8E-7 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 PRINTS PR00990 Ribokinase signature 11 32 3.8E-7 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 PRINTS PR00990 Ribokinase signature 208 219 3.8E-7 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 SUPERFAMILY SSF53613 9 281 1.71E-46 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 Gene3D G3DSA:3.40.1190.20 8 286 7.2E-55 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 Pfam PF00294 pfkB family carbohydrate kinase 173 276 2.4E-17 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 Pfam PF00294 pfkB family carbohydrate kinase 10 115 4.3E-17 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS10070 fce7577f51b6e160190f60f95e4f1055 294 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS00710 8e82ce9acd23f3f07786f3187619ba5b 268 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 9 231 3.5E-56 T 09-03-2017 IPR018713 Domain of unknown function DUF2236 ARZXY2_RS05485 6bec21d90799463d6db75e4459d63e6d 110 Gene3D G3DSA:2.40.50.100 4 80 6.2E-23 T 09-03-2017 ARZXY2_RS05485 6bec21d90799463d6db75e4459d63e6d 110 Pfam PF00364 Biotin-requiring enzyme 6 76 3.1E-19 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS05485 6bec21d90799463d6db75e4459d63e6d 110 SUPERFAMILY SSF51230 4 93 1.3E-24 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS05485 6bec21d90799463d6db75e4459d63e6d 110 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 ARZXY2_RS18630 d3cfec2ab8c489a0435e64b61d2243d6 167 Gene3D G3DSA:3.90.79.10 28 161 5.4E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS18630 d3cfec2ab8c489a0435e64b61d2243d6 167 Pfam PF00293 NUDIX domain 31 149 3.7E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS18630 d3cfec2ab8c489a0435e64b61d2243d6 167 ProSitePatterns PS00893 Nudix box signature. 62 83 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS18630 d3cfec2ab8c489a0435e64b61d2243d6 167 SUPERFAMILY SSF55811 27 162 5.82E-31 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS07840 8990a19dd5443299c27b0b7d2ed68730 363 Pfam PF06250 Protein of unknown function (DUF1016) 31 335 5.6E-115 T 09-03-2017 IPR009362 Protein of unknown function DUF1016 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 235 251 - T 09-03-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 20 433 49.741 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 Gene3D G3DSA:3.40.640.10 52 297 1.1E-104 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 SUPERFAMILY SSF53383 19 433 6.61E-169 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 Pfam PF00464 Serine hydroxymethyltransferase 22 403 1.8E-164 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 PIRSF PIRSF000412 7 436 1.4E-155 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 ARZXY2_RS19600 8059bef0bc5c7116fe0101e9715f77e8 439 Gene3D G3DSA:3.90.1150.10 298 433 1.0E-46 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS12865 6f51779049cf9b6190a39985b45cdd6e 267 Pfam PF06271 RDD family 16 144 1.2E-16 T 09-03-2017 IPR010432 RDD ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Gene3D G3DSA:3.40.50.1220 193 352 5.7E-37 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 432 451 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 SUPERFAMILY SSF52467 157 360 1.25E-37 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 329 5.0E-27 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 SUPERFAMILY SSF52518 3 177 2.06E-49 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Gene3D G3DSA:3.40.50.970 1 175 1.9E-57 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 8.0E-47 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 550 1.1E-24 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 Gene3D G3DSA:3.40.50.970 353 563 4.9E-47 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS16930 5547c6bdc2341f6a7fbe9920a03b4708 604 SUPERFAMILY SSF52518 372 567 1.03E-47 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 Pfam PF00266 Aminotransferase class-V 2 366 2.9E-67 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 SUPERFAMILY SSF53383 1 376 1.29E-95 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 Gene3D G3DSA:3.90.1150.10 249 373 1.6E-35 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 PIRSF PIRSF005572 1 382 6.2E-120 T 09-03-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ARZXY2_RS05530 6a0f4616e60f26108428eb4a98fec418 387 Gene3D G3DSA:3.40.640.10 14 248 2.5E-82 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS11025 214ed7b43f7e7127aa3dcb91fb4d8eb5 243 SMART SM00563 44 153 4.5E-24 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS11025 214ed7b43f7e7127aa3dcb91fb4d8eb5 243 Gene3D G3DSA:3.40.1130.10 27 199 7.9E-16 T 09-03-2017 ARZXY2_RS11025 214ed7b43f7e7127aa3dcb91fb4d8eb5 243 SUPERFAMILY SSF69593 20 200 4.05E-33 T 09-03-2017 ARZXY2_RS11025 214ed7b43f7e7127aa3dcb91fb4d8eb5 243 Pfam PF01553 Acyltransferase 32 150 1.8E-17 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS00890 8e68d302143d2fb5b096a4058aa442ad 132 SUPERFAMILY SSF54427 17 127 1.14E-18 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS00890 8e68d302143d2fb5b096a4058aa442ad 132 Pfam PF13474 SnoaL-like domain 16 127 8.7E-10 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS00890 8e68d302143d2fb5b096a4058aa442ad 132 Gene3D G3DSA:3.10.450.50 20 130 3.4E-15 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS11180 b2354c12394bf6b7a62bd076d1bcbf6e 219 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 13 205 30.739 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS11180 b2354c12394bf6b7a62bd076d1bcbf6e 219 SUPERFAMILY SSF50486 13 209 3.69E-52 T 09-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 ARZXY2_RS11180 b2354c12394bf6b7a62bd076d1bcbf6e 219 Gene3D G3DSA:3.10.300.10 12 211 9.1E-61 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS11180 b2354c12394bf6b7a62bd076d1bcbf6e 219 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 14 205 4.2E-51 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS11180 b2354c12394bf6b7a62bd076d1bcbf6e 219 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 15 202 3.7E-56 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 ARZXY2_RS14665 431698a9a3f903b336af96b5ad2e58f5 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 8.4E-40 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 46 122 1.4E-9 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 128 205 4.2E-29 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 Gene3D G3DSA:1.10.10.10 128 206 1.4E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 176 182 - T 09-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 128 206 1.2E-25 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 Gene3D G3DSA:3.30.160.70 41 122 1.2E-8 T 09-03-2017 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 SUPERFAMILY SSF53155 45 122 4.9E-18 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS18475 5c806b296d4185d30db2d41269df8285 208 SUPERFAMILY SSF46767 127 205 4.58E-26 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 ARZXY2_RS12045 e3d9f93ad0155dc3d8841981c500fec9 298 SUPERFAMILY SSF54001 25 154 9.22E-5 T 09-03-2017 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 Gene3D G3DSA:3.40.1690.10 212 347 8.4E-51 T 09-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 8 30 4.9E-29 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 295 316 4.9E-29 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 222 239 4.9E-29 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 266 281 4.9E-29 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 202 220 4.9E-29 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 SUPERFAMILY SSF160544 238 343 2.09E-35 T 09-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal ARZXY2_RS14440 b786125a1d2efc7734600f8c6db3d79d 361 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 340 1.9E-98 T 09-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 PIRSF PIRSF000538 2 504 1.4E-172 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 498 1.1E-227 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 452 6.5E-70 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 Gene3D G3DSA:3.30.420.40 256 500 4.7E-106 T 09-03-2017 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 253 1.1E-82 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 499 56.455 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 SUPERFAMILY SSF53067 4 255 4.45E-93 T 09-03-2017 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 Gene3D G3DSA:3.30.420.40 1 254 3.3E-109 T 09-03-2017 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 SUPERFAMILY SSF53067 256 499 1.0E-85 T 09-03-2017 ARZXY2_RS08215 63fb823b8f1c06a68cc480b1060cffd3 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 Gene3D G3DSA:1.10.3430.10 7 385 5.0E-118 T 09-03-2017 IPR029020 Ammonium/urea transporter ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 PRINTS PR00342 Rhesus blood group protein signature 264 277 9.9E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 PRINTS PR00342 Rhesus blood group protein signature 201 219 9.9E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 PRINTS PR00342 Rhesus blood group protein signature 97 113 9.9E-6 T 09-03-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 ProSitePatterns PS01219 Ammonium transporters signature. 161 186 - T 09-03-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 Pfam PF00909 Ammonium Transporter Family 8 404 5.9E-116 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 TIGRFAM TIGR00836 amt: ammonium transporter 8 404 9.7E-123 T 09-03-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 ARZXY2_RS06960 3d66582d4045b307616476c1412ae440 445 SUPERFAMILY SSF111352 7 385 6.15E-106 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 ARZXY2_RS15835 fc450db6d50ee5c703844a56320185e2 130 Pfam PF06305 Protein of unknown function (DUF1049) 63 118 5.7E-8 T 09-03-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 Gene3D G3DSA:1.10.1740.10 12 92 2.8E-15 T 09-03-2017 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 SUPERFAMILY SSF88946 11 90 5.49E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 Pfam PF08281 Sigma-70, region 4 106 157 2.1E-10 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 Pfam PF04542 Sigma-70 region 2 17 79 1.4E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 4.4E-16 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 Gene3D G3DSA:1.10.10.10 103 162 8.9E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18470 16305a97a901d11b2e4e23816ca77e11 179 SUPERFAMILY SSF88659 104 161 1.21E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS10325 69964e9a14cbe9b099d48d3828945eac 197 SUPERFAMILY SSF55821 2 196 8.01E-78 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS10325 69964e9a14cbe9b099d48d3828945eac 197 Gene3D G3DSA:3.90.870.10 2 197 1.9E-88 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS10325 69964e9a14cbe9b099d48d3828945eac 197 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 196 8.3E-83 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10325 69964e9a14cbe9b099d48d3828945eac 197 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 2 196 1.7E-70 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS01455 17644fc815a71c3d1e8fd3ebf0e8e6e2 156 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS01455 17644fc815a71c3d1e8fd3ebf0e8e6e2 156 Gene3D G3DSA:3.90.79.10 4 152 5.7E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01455 17644fc815a71c3d1e8fd3ebf0e8e6e2 156 Pfam PF00293 NUDIX domain 4 148 2.5E-12 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS01455 17644fc815a71c3d1e8fd3ebf0e8e6e2 156 SUPERFAMILY SSF55811 4 154 3.11E-14 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS06715 a8cda462deb9cb1e39fcd36fb7a916dc 580 SUPERFAMILY SSF56349 227 418 1.32E-10 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06715 a8cda462deb9cb1e39fcd36fb7a916dc 580 Gene3D G3DSA:1.10.443.10 239 410 1.0E-6 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06715 a8cda462deb9cb1e39fcd36fb7a916dc 580 Gene3D G3DSA:1.10.150.130 6 59 1.9E-4 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS18055 ed83e10fae66f3c19ce479ce1bb47cab 143 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 22 131 3.0E-31 T 09-03-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III ARZXY2_RS09240 29b1238557abb97552033fae789ed0e1 302 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 41 273 6.9E-15 T 09-03-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 ARZXY2_RS09240 29b1238557abb97552033fae789ed0e1 302 SUPERFAMILY SSF53067 116 300 1.67E-40 T 09-03-2017 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 3.5E-5 T 09-03-2017 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 3.5E-5 T 09-03-2017 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 Gene3D G3DSA:3.50.50.60 211 380 3.0E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 Gene3D G3DSA:3.50.50.60 6 96 3.0E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 7 547 2.3E-164 T 09-03-2017 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 SUPERFAMILY SSF51905 4 261 2.1E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 SUPERFAMILY SSF51905 288 358 2.1E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 SUPERFAMILY SSF51905 501 535 2.1E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17135 a35e96130fcedbbb3d264382fc972fd8 557 Pfam PF01593 Flavin containing amine oxidoreductase 14 529 4.4E-25 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 112 236 2.8E-21 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 5.1E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 5.1E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 5.1E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 Pfam PF12840 Helix-turn-helix domain 3 62 8.8E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 SMART SM00418 3 78 5.3E-14 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 Gene3D G3DSA:1.10.10.10 2 101 2.5E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 SUPERFAMILY SSF46785 2 112 7.81E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 SUPERFAMILY SSF55961 101 241 2.06E-31 T 09-03-2017 ARZXY2_RS13700 31932792b11ce4f5c785ff3b50f1075b 250 Gene3D G3DSA:3.30.530.20 107 241 2.3E-25 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS09215 acc8e4f1251844aba0f22fb85522fdbb 400 Pfam PF01384 Phosphate transporter family 181 329 3.3E-45 T 09-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 ARZXY2_RS09215 acc8e4f1251844aba0f22fb85522fdbb 400 Pfam PF01384 Phosphate transporter family 21 164 7.9E-34 T 09-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 Pfam PF01467 Cytidylyltransferase-like 377 476 3.1E-13 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 375 440 4.1E-14 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 SUPERFAMILY SSF52374 373 504 5.93E-23 T 09-03-2017 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 Gene3D G3DSA:3.40.1190.20 25 351 5.9E-53 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 Pfam PF00294 pfkB family carbohydrate kinase 48 340 4.9E-33 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 63 86 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 365 505 1.0E-58 T 09-03-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 SUPERFAMILY SSF53613 25 339 8.57E-42 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS18075 83d62d2579ddc74ae72cb45f9fff2248 512 Gene3D G3DSA:3.40.50.620 373 492 3.0E-32 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 6.5E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 Gene3D G3DSA:1.10.10.60 8 58 3.3E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 SUPERFAMILY SSF48498 80 191 3.12E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 Gene3D G3DSA:1.10.357.10 59 194 9.8E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16950 5cbed0404009fd83fb7ba36895aa5e77 204 SUPERFAMILY SSF46689 7 84 1.55E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 SMART SM00481 3 68 7.5E-15 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 Gene3D G3DSA:3.20.20.140 156 255 1.2E-36 T 09-03-2017 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 Gene3D G3DSA:3.20.20.140 2 87 1.2E-36 T 09-03-2017 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 SUPERFAMILY SSF89550 164 256 6.28E-45 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 SUPERFAMILY SSF89550 2 82 6.28E-45 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 ARZXY2_RS04380 98434adda4effb24e8fc80ebfc3a7f87 281 Pfam PF02811 PHP domain 4 101 1.5E-9 T 09-03-2017 IPR004013 PHP domain GO:0003824 ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 SUPERFAMILY SSF46785 3 112 7.62E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 Pfam PF03466 LysR substrate binding domain 89 286 3.3E-29 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 SUPERFAMILY SSF53850 89 290 1.81E-33 T 09-03-2017 ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 Gene3D G3DSA:1.10.10.10 5 79 2.4E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 Gene3D G3DSA:3.40.190.10 173 254 3.8E-11 T 09-03-2017 ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 5.7E-14 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS16820 52049316b72aa4c5114494c39705616a 305 Gene3D G3DSA:3.40.190.10 88 172 5.1E-8 T 09-03-2017 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 Gene3D G3DSA:3.20.20.60 39 300 1.9E-103 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 SUPERFAMILY SSF51621 39 299 5.5E-96 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 39 300 3.8E-84 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 40 300 40.356 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 PIRSF PIRSF000388 31 300 1.5E-103 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 ARZXY2_RS10755 770c881e5d4f70e305249e6e79b4a076 300 Pfam PF02548 Ketopantoate hydroxymethyltransferase 39 295 3.0E-101 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 ARZXY2_RS01975 75c90adbdf3784c5b94f7ded4c5b2abf 301 Gene3D G3DSA:3.20.20.70 1 295 1.5E-67 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS01975 75c90adbdf3784c5b94f7ded4c5b2abf 301 SMART SM01130 2 295 4.9E-69 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS01975 75c90adbdf3784c5b94f7ded4c5b2abf 301 PIRSF PIRSF001365 1 301 1.2E-51 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS01975 75c90adbdf3784c5b94f7ded4c5b2abf 301 Pfam PF00701 Dihydrodipicolinate synthetase family 3 293 9.0E-53 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS01975 75c90adbdf3784c5b94f7ded4c5b2abf 301 SUPERFAMILY SSF51569 1 294 2.93E-62 T 09-03-2017 ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 Gene3D G3DSA:3.30.360.10 133 323 7.8E-35 T 09-03-2017 ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 236 9.6E-12 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 2.1E-25 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 SUPERFAMILY SSF51735 4 153 9.02E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 SUPERFAMILY SSF55347 129 280 1.29E-24 T 09-03-2017 ARZXY2_RS16260 ff1f5598c168b3967de246fbf989c757 335 Gene3D G3DSA:3.40.50.720 3 132 3.7E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04660 7e1867b67c274880244c796b3ce0596e 222 SUPERFAMILY SSF46785 15 195 6.82E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04660 7e1867b67c274880244c796b3ce0596e 222 Gene3D G3DSA:1.10.10.10 18 92 6.8E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13575 641022b9a91320ae15406d7881fc0b87 395 Pfam PF03741 Integral membrane protein TerC family 69 272 8.1E-49 T 09-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 ARZXY2_RS13575 641022b9a91320ae15406d7881fc0b87 395 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 317 7.2E-110 T 09-03-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 ARZXY2_RS01015 125ef27c190e626b17ce6dbee1544aa9 216 Pfam PF00753 Metallo-beta-lactamase superfamily 22 195 6.5E-11 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS01015 125ef27c190e626b17ce6dbee1544aa9 216 SUPERFAMILY SSF56281 12 212 3.52E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS01015 125ef27c190e626b17ce6dbee1544aa9 216 Gene3D G3DSA:3.60.15.10 10 214 1.1E-44 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS01015 125ef27c190e626b17ce6dbee1544aa9 216 SMART SM00849 22 195 6.8E-26 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 Pfam PF01494 FAD binding domain 128 305 8.1E-12 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 SUPERFAMILY SSF51905 240 325 6.08E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 SUPERFAMILY SSF51905 8 146 6.08E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 253 268 5.1E-8 T 09-03-2017 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 284 5.1E-8 T 09-03-2017 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.1E-8 T 09-03-2017 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 44 6.4E-6 T 09-03-2017 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 Gene3D G3DSA:3.50.50.60 241 318 8.3E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS07905 caf21f7eb5099c70a3ebc4f4f0a6527a 353 Gene3D G3DSA:3.50.50.60 5 152 8.3E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS04405 e78c94847eb20942dc337b5c6d0d2ea2 485 SUPERFAMILY SSF50249 21 410 1.14E-78 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS04405 e78c94847eb20942dc337b5c6d0d2ea2 485 Pfam PF00773 RNB domain 57 362 3.3E-37 T 09-03-2017 ARZXY2_RS04405 e78c94847eb20942dc337b5c6d0d2ea2 485 SMART SM00955 54 371 2.7E-43 T 09-03-2017 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 291 1.3E-114 T 09-03-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 PIRSF PIRSF000103 1 292 5.2E-80 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 Gene3D G3DSA:1.10.1040.10 165 289 8.3E-39 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 Gene3D G3DSA:3.40.50.720 2 163 7.8E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 SUPERFAMILY SSF48179 163 290 2.61E-36 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 SUPERFAMILY SSF51735 3 163 5.21E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 09-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 3.8E-37 T 09-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 ARZXY2_RS01235 a0cc66a8cde1c6b5165826d9c3c68e34 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 8.9E-52 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS10490 5b1f830c82503b8a3380ece9c83bea71 325 SUPERFAMILY SSF51430 3 319 5.76E-90 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS10490 5b1f830c82503b8a3380ece9c83bea71 325 Pfam PF00248 Aldo/keto reductase family 17 315 3.7E-60 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS10490 5b1f830c82503b8a3380ece9c83bea71 325 Gene3D G3DSA:3.20.20.100 3 319 8.5E-90 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS10490 5b1f830c82503b8a3380ece9c83bea71 325 PRINTS PR00069 Aldo-keto reductase signature 144 161 7.4E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS10490 5b1f830c82503b8a3380ece9c83bea71 325 PRINTS PR00069 Aldo-keto reductase signature 44 68 7.4E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS12225 9d54eb78a08045430a832e46a105285a 368 SUPERFAMILY SSF52540 4 263 7.91E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12225 9d54eb78a08045430a832e46a105285a 368 Gene3D G3DSA:3.40.50.300 4 181 2.6E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12225 9d54eb78a08045430a832e46a105285a 368 Pfam PF13191 AAA ATPase domain 32 166 9.4E-10 T 09-03-2017 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 SMART SM00850 136 231 1.4E-27 T 09-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-19 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 Gene3D G3DSA:2.40.50.40 128 196 2.9E-17 T 09-03-2017 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 Gene3D G3DSA:3.40.50.2300 1 118 6.7E-28 T 09-03-2017 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 Pfam PF04397 LytTr DNA-binding domain 138 230 6.5E-22 T 09-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 SUPERFAMILY SSF52172 1 118 4.84E-27 T 09-03-2017 IPR011006 CheY-like superfamily ARZXY2_RS11765 a05429b2e8199309ecb46df47d7e7ff4 239 SMART SM00448 2 113 4.6E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 15 156 18.941 T 09-03-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 Gene3D G3DSA:3.100.10.10 43 156 1.4E-33 T 09-03-2017 ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 SUPERFAMILY SSF52080 16 155 1.57E-40 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 ProSitePatterns PS00475 Ribosomal protein L15 signature. 120 150 - T 09-03-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 15 153 4.7E-45 T 09-03-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS03585 790eb1c8dfe91ce45f1d7705bc60c9fc 156 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 38 154 1.4E-31 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P ARZXY2_RS15610 bcd3ff347302119625bc1d97ef0ac286 246 SUPERFAMILY SSF51658 5 214 5.71E-37 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS15610 bcd3ff347302119625bc1d97ef0ac286 246 Pfam PF01261 Xylose isomerase-like TIM barrel 28 194 3.0E-20 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS15610 bcd3ff347302119625bc1d97ef0ac286 246 Gene3D G3DSA:3.20.20.150 3 240 2.8E-48 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 13 498 8.5E-140 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 SUPERFAMILY SSF89095 351 498 5.49E-22 T 09-03-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 SUPERFAMILY SSF55931 18 320 8.5E-109 T 09-03-2017 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 Pfam PF02934 GatB/GatE catalytic domain 19 313 2.0E-102 T 09-03-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 SMART SM00845 351 498 3.6E-52 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 499 34.574 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 Gene3D G3DSA:1.10.10.410 447 498 1.5E-4 T 09-03-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 Pfam PF02637 GatB domain 352 498 1.6E-37 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 ARZXY2_RS12345 8560a05e1cc6c2115abaa69369eb5b00 502 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 164 178 - T 09-03-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 82 283 4.1E-27 T 09-03-2017 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 Gene3D G3DSA:3.90.15.10 87 205 2.5E-29 T 09-03-2017 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 SUPERFAMILY SSF56349 78 299 3.53E-56 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 SUPERFAMILY SSF55869 17 83 3.53E-20 T 09-03-2017 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 231 245 2.6E-7 T 09-03-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 145 159 2.6E-7 T 09-03-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 122 141 2.6E-7 T 09-03-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 279 290 2.6E-7 T 09-03-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 ARZXY2_RS17255 5cfcbf07c9147ba6ae55f820f5107b07 318 Gene3D G3DSA:1.20.120.380 233 304 3.8E-20 T 09-03-2017 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 ARZXY2_RS14345 26bef10697d1740620073f4bf66dc3f5 280 Pfam PF08021 Siderophore-interacting FAD-binding domain 23 137 3.6E-34 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting ARZXY2_RS14345 26bef10697d1740620073f4bf66dc3f5 280 Pfam PF04954 Siderophore-interacting protein 144 263 2.9E-34 T 09-03-2017 IPR007037 Siderophore-interacting protein ARZXY2_RS14345 26bef10697d1740620073f4bf66dc3f5 280 Gene3D G3DSA:3.40.50.80 139 274 4.6E-42 T 09-03-2017 ARZXY2_RS14345 26bef10697d1740620073f4bf66dc3f5 280 SUPERFAMILY SSF63380 19 141 6.59E-11 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS14345 26bef10697d1740620073f4bf66dc3f5 280 Gene3D G3DSA:2.40.30.10 14 136 4.3E-32 T 09-03-2017 ARZXY2_RS13950 1c4c8e1226c0628df1eb90a8ae7e0167 252 Pfam PF03932 CutC family 2 206 2.1E-54 T 09-03-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 ARZXY2_RS13950 1c4c8e1226c0628df1eb90a8ae7e0167 252 SUPERFAMILY SSF110395 1 246 2.88E-54 T 09-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 ARZXY2_RS13950 1c4c8e1226c0628df1eb90a8ae7e0167 252 Gene3D G3DSA:3.20.20.380 2 247 3.7E-70 T 09-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 ARZXY2_RS20340 f7bede80fb5b68cf472051d223c7d191 459 SUPERFAMILY SSF143548 17 159 6.02E-46 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS20340 f7bede80fb5b68cf472051d223c7d191 459 Pfam PF03315 Serine dehydratase beta chain 4 155 1.2E-56 T 09-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS20340 f7bede80fb5b68cf472051d223c7d191 459 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 456 1.9E-212 T 09-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 ARZXY2_RS20340 f7bede80fb5b68cf472051d223c7d191 459 Pfam PF03313 Serine dehydratase alpha chain 188 453 3.7E-104 T 09-03-2017 IPR005130 Serine dehydratase-like, alpha subunit ARZXY2_RS20340 f7bede80fb5b68cf472051d223c7d191 459 Gene3D G3DSA:3.30.1330.90 11 158 4.1E-53 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS04200 1919117cb7868478b59a7ad482baf918 170 Pfam PF08974 Domain of unknown function (DUF1877) 1 166 4.2E-8 T 09-03-2017 IPR015068 Protein of unknown function DUF1877 ARZXY2_RS04200 1919117cb7868478b59a7ad482baf918 170 SUPERFAMILY SSF111069 48 169 1.57E-5 T 09-03-2017 IPR015068 Protein of unknown function DUF1877 ARZXY2_RS04200 1919117cb7868478b59a7ad482baf918 170 Gene3D G3DSA:3.40.1760.10 1 169 3.4E-11 T 09-03-2017 IPR015068 Protein of unknown function DUF1877 ARZXY2_RS08670 5070bfe79243cc13702a45c3a91416e5 348 Gene3D G3DSA:3.40.50.150 91 297 2.2E-60 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08670 5070bfe79243cc13702a45c3a91416e5 348 Gene3D G3DSA:3.10.330.20 17 90 5.9E-30 T 09-03-2017 ARZXY2_RS08670 5070bfe79243cc13702a45c3a91416e5 348 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 96 261 1.6E-19 T 09-03-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 ARZXY2_RS08670 5070bfe79243cc13702a45c3a91416e5 348 SUPERFAMILY SSF53335 28 285 6.34E-64 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08670 5070bfe79243cc13702a45c3a91416e5 348 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 26 76 2.0E-26 T 09-03-2017 ARZXY2_RS17905 79f34f2e522ffdd9f115ddbb528d3320 143 Pfam PF07883 Cupin domain 39 102 1.5E-13 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS17905 79f34f2e522ffdd9f115ddbb528d3320 143 Gene3D G3DSA:2.60.120.10 6 127 2.0E-28 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS17905 79f34f2e522ffdd9f115ddbb528d3320 143 SUPERFAMILY SSF51182 6 130 1.82E-30 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 SUPERFAMILY SSF46689 3 76 7.98E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 SUPERFAMILY SSF48498 81 188 2.22E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.1E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.1E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 6.5E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS12785 4d75e50c7103edaea8287f16d5192318 199 Gene3D G3DSA:1.10.357.10 2 187 8.8E-45 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Pfam PF00501 AMP-binding enzyme 10 455 6.5E-31 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Gene3D G3DSA:3.40.50.980 191 343 6.4E-18 T 09-03-2017 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 SUPERFAMILY SSF56801 11 557 2.75E-62 T 09-03-2017 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 536 1.5E-6 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Gene3D G3DSA:3.40.50.980 167 190 1.6E-18 T 09-03-2017 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Gene3D G3DSA:3.40.50.980 20 110 1.6E-18 T 09-03-2017 ARZXY2_RS03615 743f9bcc9d88fc032c2642a9811c9051 565 Gene3D G3DSA:3.30.300.30 450 551 3.2E-13 T 09-03-2017 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 ProSitePatterns PS01117 MarR-type HTH domain signature. 83 117 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 SUPERFAMILY SSF46785 14 158 4.71E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 Gene3D G3DSA:1.10.10.10 14 156 2.5E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 SMART SM00347 44 144 6.2E-17 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 Pfam PF01047 MarR family 55 108 4.2E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 1.9E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 1.9E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 1.9E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS11395 97aeb5aa74d2e2a484d46fa0ecc0d7fb 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 1.9E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 Gene3D G3DSA:2.30.330.10 152 231 1.1E-27 T 09-03-2017 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 159 228 8.0E-24 T 09-03-2017 IPR001543 Surface presentation of antigen (SpoA) ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 SUPERFAMILY SSF101801 156 231 7.98E-21 T 09-03-2017 IPR001543 Surface presentation of antigen (SpoA) ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 PRINTS PR00956 Flagellar motor switch protein FliN signature 191 204 9.3E-23 T 09-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 PRINTS PR00956 Flagellar motor switch protein FliN signature 175 191 9.3E-23 T 09-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 PRINTS PR00956 Flagellar motor switch protein FliN signature 204 219 9.3E-23 T 09-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 PRINTS PR00956 Flagellar motor switch protein FliN signature 158 174 9.3E-23 T 09-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 ARZXY2_RS14465 036469c65fc3b85d281d4c7a9904c699 235 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 157 229 4.8E-26 T 09-03-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 ARZXY2_RS13505 1aee3a51e9639342cfdaae407696a105 418 Pfam PF11795 Uncharacterized protein conserved in bacteria N-term (DUF3322) 14 193 2.5E-38 T 09-03-2017 IPR024537 Domain of unknown function DUF3322 ARZXY2_RS13505 1aee3a51e9639342cfdaae407696a105 418 PIRSF PIRSF028408 10 417 6.7E-76 T 09-03-2017 IPR014544 Uncharacterised conserved protein UCP028408 ARZXY2_RS13505 1aee3a51e9639342cfdaae407696a105 418 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 239 414 3.0E-56 T 09-03-2017 IPR024534 Domain of unknown function DUF2220 ARZXY2_RS02060 91a5f4c10d519a84ee103b50c99c158b 253 Pfam PF04854 Protein of unknown function, DUF624 20 95 1.1E-19 T 09-03-2017 IPR006938 Protein of unknown function DUF624 ARZXY2_RS12445 8979330457f0db8ae2eb07cbf54b0610 323 Gene3D G3DSA:3.40.50.300 27 188 1.0E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12445 8979330457f0db8ae2eb07cbf54b0610 323 SUPERFAMILY SSF52540 13 289 7.64E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12445 8979330457f0db8ae2eb07cbf54b0610 323 Gene3D G3DSA:1.10.8.300 207 314 4.5E-32 T 09-03-2017 ARZXY2_RS12445 8979330457f0db8ae2eb07cbf54b0610 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 175 8.7E-63 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 ARZXY2_RS12445 8979330457f0db8ae2eb07cbf54b0610 323 PIRSF PIRSF002849 1 319 2.7E-131 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted ARZXY2_RS13230 4ac1de1e61cfb4ed2b3f1b2186396a94 434 Gene3D G3DSA:3.40.190.10 38 220 4.7E-38 T 09-03-2017 ARZXY2_RS13230 4ac1de1e61cfb4ed2b3f1b2186396a94 434 SUPERFAMILY SSF53850 40 430 6.21E-61 T 09-03-2017 ARZXY2_RS13230 4ac1de1e61cfb4ed2b3f1b2186396a94 434 Pfam PF01547 Bacterial extracellular solute-binding protein 53 343 1.2E-31 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS16035 cc519fe0c7dccae22d5d954fe6c56359 275 Pfam PF13560 Helix-turn-helix domain 8 80 6.6E-17 T 09-03-2017 ARZXY2_RS16035 cc519fe0c7dccae22d5d954fe6c56359 275 Gene3D G3DSA:1.10.260.40 4 80 1.4E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16035 cc519fe0c7dccae22d5d954fe6c56359 275 SMART SM00530 12 84 1.3E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS16035 cc519fe0c7dccae22d5d954fe6c56359 275 SUPERFAMILY SSF47413 34 81 1.94E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 2.6E-27 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 Gene3D G3DSA:3.10.20.70 6 107 6.8E-38 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 233 248 - T 09-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 441 1.3E-136 T 09-03-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 SMART SM01230 104 356 1.8E-125 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 Gene3D G3DSA:3.30.590.10 108 431 4.5E-117 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 Pfam PF00120 Glutamine synthetase, catalytic domain 105 441 1.0E-125 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 SUPERFAMILY SSF55931 105 443 1.37E-118 T 09-03-2017 ARZXY2_RS10750 e0b19bccb22b1ced599b98706263af13 446 SUPERFAMILY SSF54368 8 102 3.01E-29 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS18005 11820d19e763da3e4d6c585708083f89 183 SUPERFAMILY SSF53271 5 183 1.75E-54 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS18005 11820d19e763da3e4d6c585708083f89 183 Pfam PF00156 Phosphoribosyl transferase domain 18 164 2.3E-22 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS18005 11820d19e763da3e4d6c585708083f89 183 Gene3D G3DSA:3.40.50.2020 3 183 5.0E-79 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS18005 11820d19e763da3e4d6c585708083f89 183 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 13 177 2.2E-61 T 09-03-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 SUPERFAMILY SSF46785 4 86 3.87E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 SMART SM00418 5 83 7.3E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.3E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.3E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 4.3E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 Gene3D G3DSA:1.10.10.10 4 84 6.4E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01940 71878494a058bd0458ea41f5e87dca4c 179 Pfam PF01022 Bacterial regulatory protein, arsR family 14 57 5.8E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS13570 55368a8cef1c2246c42eef1358a0bcf2 418 Gene3D G3DSA:3.40.50.1010 10 173 6.3E-23 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS13570 55368a8cef1c2246c42eef1358a0bcf2 418 Pfam PF01936 NYN domain 15 169 5.1E-16 T 09-03-2017 IPR021139 NYN domain, limkain-b1-type ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 183 2.3E-7 T 09-03-2017 ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.0E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.0E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.0E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 Gene3D G3DSA:3.40.50.720 7 237 2.1E-81 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.3E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 SUPERFAMILY SSF51735 8 237 2.05E-78 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08920 b9d14bd556ccfd55eac42244c13a223a 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 237 1.0E-56 T 09-03-2017 ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 Gene3D G3DSA:3.90.980.10 9 136 1.4E-28 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 Gene3D G3DSA:3.40.1360.10 137 258 2.9E-18 T 09-03-2017 ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 Pfam PF08275 DNA primase catalytic core, N-terminal domain 20 147 5.7E-26 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 SUPERFAMILY SSF56731 10 301 1.31E-54 T 09-03-2017 ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 Pfam PF13155 Toprim-like 156 230 4.9E-11 T 09-03-2017 ARZXY2_RS19470 08ee1e46d20b239f78360e989646ed05 363 SMART SM00493 153 226 0.0019 T 09-03-2017 IPR006171 Toprim domain ARZXY2_RS09010 30ee18877dc55365a4bb4301e86af382 319 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS09010 30ee18877dc55365a4bb4301e86af382 319 SUPERFAMILY SSF52540 7 234 3.34E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS09010 30ee18877dc55365a4bb4301e86af382 319 SMART SM00382 41 219 5.2E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09010 30ee18877dc55365a4bb4301e86af382 319 Pfam PF00005 ABC transporter 33 171 3.0E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS09010 30ee18877dc55365a4bb4301e86af382 319 Gene3D G3DSA:3.40.50.300 5 235 1.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 Gene3D G3DSA:3.40.1160.10 22 269 3.4E-55 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 SMART SM00359 291 374 3.7E-17 T 09-03-2017 IPR002478 PUA domain GO:0003723 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 Pfam PF01472 PUA domain 291 360 5.9E-19 T 09-03-2017 IPR002478 PUA domain GO:0003723 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 SUPERFAMILY SSF53633 23 269 2.23E-61 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 Hamap MF_00456 Glutamate 5-kinase [proB]. 23 272 33.919 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 Pfam PF00696 Amino acid kinase family 23 252 7.6E-42 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PRINTS PR00474 Glutamate 5-kinase family signature 226 246 1.0E-53 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PRINTS PR00474 Glutamate 5-kinase family signature 134 155 1.0E-53 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PRINTS PR00474 Glutamate 5-kinase family signature 166 193 1.0E-53 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PRINTS PR00474 Glutamate 5-kinase family signature 60 74 1.0E-53 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PRINTS PR00474 Glutamate 5-kinase family signature 94 122 1.0E-53 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 ProSitePatterns PS00902 Glutamate 5-kinase signature. 224 241 - T 09-03-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 SUPERFAMILY SSF88697 290 381 4.48E-22 T 09-03-2017 IPR015947 PUA-like domain ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 PIRSF PIRSF000729 18 383 4.4E-120 T 09-03-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 TIGRFAM TIGR01027 proB: glutamate 5-kinase 23 380 4.7E-122 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 ARZXY2_RS07685 20c8f5e7c275c67faade262f5979a2d9 392 Gene3D G3DSA:2.30.130.10 289 380 8.9E-25 T 09-03-2017 IPR015947 PUA-like domain ARZXY2_RS18920 0e9f5f63b73918fe7ed35de1a3062577 446 Pfam PF01554 MatE 22 181 1.5E-30 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ARZXY2_RS18920 0e9f5f63b73918fe7ed35de1a3062577 446 Pfam PF01554 MatE 253 393 4.1E-18 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ARZXY2_RS18920 0e9f5f63b73918fe7ed35de1a3062577 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 404 4.7E-93 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ARZXY2_RS18920 0e9f5f63b73918fe7ed35de1a3062577 446 PIRSF PIRSF006603 7 443 1.9E-59 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 183 33.045 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 189 3.2E-53 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 Gene3D G3DSA:3.40.50.1470 3 190 4.1E-69 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 SUPERFAMILY SSF53178 4 190 4.58E-62 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS12760 0490e65666e03232ac0dcd32c03031df 194 Pfam PF01195 Peptidyl-tRNA hydrolase 6 187 4.2E-53 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 ARZXY2_RS04125 fd64ad9fcd923c0d596e91d2c1d6a2aa 425 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 28 415 2.2E-114 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS04125 fd64ad9fcd923c0d596e91d2c1d6a2aa 425 Pfam PF13742 OB-fold nucleic acid binding domain 28 117 5.0E-12 T 09-03-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 ARZXY2_RS04125 fd64ad9fcd923c0d596e91d2c1d6a2aa 425 Pfam PF02601 Exonuclease VII, large subunit 140 356 1.5E-58 T 09-03-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 ARZXY2_RS04125 fd64ad9fcd923c0d596e91d2c1d6a2aa 425 Pfam PF02601 Exonuclease VII, large subunit 336 414 1.3E-7 T 09-03-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 ARZXY2_RS04125 fd64ad9fcd923c0d596e91d2c1d6a2aa 425 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 18 417 21.65 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 SUPERFAMILY SSF51055 451 504 2.35E-12 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 SUPERFAMILY SSF51445 48 328 1.74E-19 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Gene3D G3DSA:3.20.20.80 56 342 2.6E-11 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Pfam PF00704 Glycosyl hydrolases family 18 68 268 2.0E-10 T 09-03-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 SMART SM00495 390 438 3.3E-4 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 SMART SM00495 458 506 3.1E-11 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Gene3D G3DSA:2.10.10.20 388 440 1.4E-12 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Gene3D G3DSA:2.10.10.20 455 507 1.8E-15 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Pfam PF02839 Carbohydrate binding domain 458 503 4.1E-14 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 Pfam PF02839 Carbohydrate binding domain 390 435 1.4E-6 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS02450 5dc32a82d9735a6231f9f42dabff62c4 521 SUPERFAMILY SSF51055 387 440 1.96E-11 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 ARZXY2_RS17010 058883dc7f159a3e1e7835a5b9cb40b1 136 Pfam PF07883 Cupin domain 44 110 2.7E-10 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS17010 058883dc7f159a3e1e7835a5b9cb40b1 136 SUPERFAMILY SSF51182 4 118 1.83E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS17010 058883dc7f159a3e1e7835a5b9cb40b1 136 Gene3D G3DSA:2.60.120.10 5 114 1.6E-17 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS14505 78b5433bcaa37bee690d3de3e30321cc 140 Pfam PF03963 Flagellar hook capping protein - N-terminal region 9 69 3.8E-16 T 09-03-2017 IPR005648 Flagellar hook capping protein ARZXY2_RS20235 6d311d4bc4e631d3b06f3f25d1447712 261 SMART SM00382 34 223 5.1E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS20235 6d311d4bc4e631d3b06f3f25d1447712 261 Gene3D G3DSA:3.40.50.300 6 227 8.4E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20235 6d311d4bc4e631d3b06f3f25d1447712 261 Pfam PF00005 ABC transporter 25 166 2.3E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS20235 6d311d4bc4e631d3b06f3f25d1447712 261 SUPERFAMILY SSF52540 6 229 4.49E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20235 6d311d4bc4e631d3b06f3f25d1447712 261 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13075 93c436d73cc52605229e3f64b1455c0f 256 SMART SM00382 45 243 1.4E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS13075 93c436d73cc52605229e3f64b1455c0f 256 SUPERFAMILY SSF52540 19 250 1.38E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13075 93c436d73cc52605229e3f64b1455c0f 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS13075 93c436d73cc52605229e3f64b1455c0f 256 Gene3D G3DSA:3.40.50.300 16 248 1.8E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13075 93c436d73cc52605229e3f64b1455c0f 256 Pfam PF00005 ABC transporter 36 180 1.1E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02035 25e2c3d2e7084b382a8c342149600abe 317 Gene3D G3DSA:1.10.3720.10 23 303 1.2E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02035 25e2c3d2e7084b382a8c342149600abe 317 SUPERFAMILY SSF160964 33 76 1.57E-6 T 09-03-2017 ARZXY2_RS02035 25e2c3d2e7084b382a8c342149600abe 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 2.8E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02035 25e2c3d2e7084b382a8c342149600abe 317 SUPERFAMILY SSF161098 73 301 5.36E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 TIGRFAM TIGR03356 BGL: beta-galactosidase 19 465 8.1E-153 T 09-03-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 SUPERFAMILY SSF51445 18 473 6.17E-143 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 Pfam PF00232 Glycosyl hydrolase family 1 15 472 5.4E-138 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 444 456 1.9E-20 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 1.9E-20 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 1.9E-20 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 297 311 1.9E-20 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 420 437 1.9E-20 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 ARZXY2_RS03485 c460ab70e96b10dfe6801370b158ad57 479 Gene3D G3DSA:3.20.20.80 16 473 9.1E-137 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 SMART SM00487 309 499 2.2E-8 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Pfam PF13091 PLD-like domain 139 271 2.4E-13 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 SMART SM00490 565 646 6.0E-13 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Gene3D G3DSA:3.30.870.10 129 275 2.7E-11 T 09-03-2017 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 SUPERFAMILY SSF56024 125 274 4.4E-10 T 09-03-2017 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 SUPERFAMILY SSF52540 365 506 2.5E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 SUPERFAMILY SSF52540 534 666 2.5E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Pfam PF04851 Type III restriction enzyme, res subunit 313 465 7.9E-30 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Pfam PF11907 Domain of unknown function (DUF3427) 865 1045 7.2E-23 T 09-03-2017 IPR021835 Protein of unknown function DUF3427 ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Gene3D G3DSA:3.40.50.300 533 665 4.5E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Gene3D G3DSA:3.40.50.300 315 468 3.2E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13555 c5044b9d1506d9a900135ced86dc3a25 1051 Pfam PF00271 Helicase conserved C-terminal domain 551 644 3.2E-11 T 09-03-2017 IPR001650 Helicase, C-terminal ARZXY2_RS10035 f247a91ece35d96c2c4aa3d4c5d9d00b 167 Gene3D G3DSA:3.20.80.10 13 156 6.1E-12 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS10035 f247a91ece35d96c2c4aa3d4c5d9d00b 167 SMART SM00871 6 156 2.5E-16 T 09-03-2017 IPR010499 Bacterial transcription activator, effector binding ARZXY2_RS10035 f247a91ece35d96c2c4aa3d4c5d9d00b 167 SUPERFAMILY SSF55136 9 155 1.17E-16 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS10035 f247a91ece35d96c2c4aa3d4c5d9d00b 167 Pfam PF06445 GyrI-like small molecule binding domain 7 155 5.6E-11 T 09-03-2017 IPR029442 GyrI-like small molecule binding domain ARZXY2_RS00105 3588b3b5056e289487c275a97e7e9cd7 309 SUPERFAMILY SSF53686 5 305 4.71E-74 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS00105 3588b3b5056e289487c275a97e7e9cd7 309 Gene3D G3DSA:3.40.50.1100 70 307 4.3E-58 T 09-03-2017 ARZXY2_RS00105 3588b3b5056e289487c275a97e7e9cd7 309 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 39 52 - T 09-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 ARZXY2_RS00105 3588b3b5056e289487c275a97e7e9cd7 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 301 4.2E-69 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS02225 8934a0804c56a65cf678f4e58a13cea7 145 SUPERFAMILY SSF54593 6 144 5.98E-10 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS02225 8934a0804c56a65cf678f4e58a13cea7 145 Gene3D G3DSA:3.10.180.10 9 144 1.4E-5 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS12335 c63e85e5619bf83ccc854e8ba0cd4bf1 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 300 2.8E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS12335 c63e85e5619bf83ccc854e8ba0cd4bf1 307 SUPERFAMILY SSF161098 29 307 1.18E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS12335 c63e85e5619bf83ccc854e8ba0cd4bf1 307 Gene3D G3DSA:1.10.3720.10 25 294 7.6E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04810 f0d84ec671c6d358e42f910fa8e2e60d 432 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 152 368 6.7E-10 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain ARZXY2_RS04810 f0d84ec671c6d358e42f910fa8e2e60d 432 SUPERFAMILY SSF52540 150 408 3.82E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04810 f0d84ec671c6d358e42f910fa8e2e60d 432 Gene3D G3DSA:3.40.50.300 149 408 3.0E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16290 2e0760a680ef0da0f86f6440a7ae92d2 434 SMART SM00894 397 433 4.1E-18 T 09-03-2017 IPR008613 Excalibur calcium-binding domain ARZXY2_RS16290 2e0760a680ef0da0f86f6440a7ae92d2 434 Pfam PF05901 Excalibur calcium-binding domain 398 433 3.2E-12 T 09-03-2017 IPR008613 Excalibur calcium-binding domain ARZXY2_RS16290 2e0760a680ef0da0f86f6440a7ae92d2 434 Pfam PF07510 Protein of unknown function (DUF1524) 174 310 7.5E-14 T 09-03-2017 IPR011089 Domain of unknown function DUF1524 ARZXY2_RS20275 069cb796d3098c954de935f411d69a64 434 Gene3D G3DSA:1.20.1250.20 40 216 2.6E-21 T 09-03-2017 ARZXY2_RS20275 069cb796d3098c954de935f411d69a64 434 Gene3D G3DSA:1.20.1250.20 244 430 1.0E-21 T 09-03-2017 ARZXY2_RS20275 069cb796d3098c954de935f411d69a64 434 Pfam PF07690 Major Facilitator Superfamily 293 427 3.9E-17 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS20275 069cb796d3098c954de935f411d69a64 434 Pfam PF07690 Major Facilitator Superfamily 54 275 1.3E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS20275 069cb796d3098c954de935f411d69a64 434 SUPERFAMILY SSF103473 30 430 1.03E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 1.2E-62 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 8 528 8.0E-182 T 09-03-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 SUPERFAMILY SSF51735 103 284 3.89E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 SUPERFAMILY SSF55021 455 528 1.37E-14 T 09-03-2017 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Gene3D G3DSA:3.40.50.720 110 285 1.7E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Pfam PF01842 ACT domain 458 517 1.1E-8 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Gene3D G3DSA:3.30.1330.90 321 448 7.2E-40 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 SUPERFAMILY SSF52283 5 137 9.83E-36 T 09-03-2017 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 SUPERFAMILY SSF143548 323 451 9.42E-33 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Gene3D G3DSA:3.30.70.260 449 525 4.4E-18 T 09-03-2017 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Gene3D G3DSA:3.40.50.720 4 109 1.0E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 315 2.6E-33 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS05640 2b7a8e472eec3fae7cb8bd973727f0e4 531 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ARZXY2_RS14985 7014e8f6432113749f0d1a437045ebe4 346 SUPERFAMILY SSF54631 207 340 1.89E-22 T 09-03-2017 ARZXY2_RS14985 7014e8f6432113749f0d1a437045ebe4 346 Pfam PF01595 Domain of unknown function DUF21 11 201 4.1E-38 T 09-03-2017 IPR002550 Domain of unknown function DUF21 ARZXY2_RS14985 7014e8f6432113749f0d1a437045ebe4 346 Pfam PF00571 CBS domain 223 271 5.9E-4 T 09-03-2017 IPR000644 CBS domain ARZXY2_RS14985 7014e8f6432113749f0d1a437045ebe4 346 Gene3D G3DSA:3.10.580.10 221 336 2.7E-13 T 09-03-2017 ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 24 136 5.0E-25 T 09-03-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 3 355 40.158 T 09-03-2017 IPR023763 DNA integrity scanning protein, DisA ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 SUPERFAMILY SSF47781 281 349 4.08E-13 T 09-03-2017 IPR010994 RuvA domain 2-like ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Gene3D G3DSA:1.10.150.20 295 345 2.9E-11 T 09-03-2017 ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Pfam PF10635 DisA bacterial checkpoint controller linker region 141 281 2.4E-45 T 09-03-2017 IPR018906 DNA integrity scanning, DisA, linker region ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 SUPERFAMILY SSF143597 17 140 5.1E-27 T 09-03-2017 ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Gene3D G3DSA:3.40.1700.10 18 139 6.2E-31 T 09-03-2017 ARZXY2_RS17745 462cd0445a3d9bd61a9cc26b054d864d 358 Pfam PF12826 Helix-hairpin-helix motif 294 346 7.1E-9 T 09-03-2017 ARZXY2_RS17865 a2ac031df36fae8a005b503c9e933fe3 296 Pfam PF12697 Alpha/beta hydrolase family 40 253 3.2E-13 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17865 a2ac031df36fae8a005b503c9e933fe3 296 Gene3D G3DSA:3.40.50.1820 5 286 3.0E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17865 a2ac031df36fae8a005b503c9e933fe3 296 SUPERFAMILY SSF53474 3 137 4.68E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17865 a2ac031df36fae8a005b503c9e933fe3 296 SUPERFAMILY SSF53474 219 286 4.68E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS00230 b0702fe20cb6034a5bb561ab79fcdff2 235 Gene3D G3DSA:3.40.225.10 11 233 2.9E-65 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00230 b0702fe20cb6034a5bb561ab79fcdff2 235 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 204 4.0E-46 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00230 b0702fe20cb6034a5bb561ab79fcdff2 235 SMART SM01007 13 206 1.6E-61 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS00230 b0702fe20cb6034a5bb561ab79fcdff2 235 SUPERFAMILY SSF53639 6 230 4.12E-58 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal ARZXY2_RS05455 c879447ef68cd9e8684782b16cf6fe7f 458 Gene3D G3DSA:1.20.1250.20 281 447 1.9E-11 T 09-03-2017 ARZXY2_RS05455 c879447ef68cd9e8684782b16cf6fe7f 458 Gene3D G3DSA:1.20.1250.20 69 244 1.7E-8 T 09-03-2017 ARZXY2_RS05455 c879447ef68cd9e8684782b16cf6fe7f 458 SUPERFAMILY SSF103473 22 455 9.42E-25 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS05455 c879447ef68cd9e8684782b16cf6fe7f 458 Pfam PF07690 Major Facilitator Superfamily 66 400 2.2E-8 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09085 c74fdc3ae9f1df84e474deccfd4fa4b7 326 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 30.081 T 09-03-2017 IPR003802 Sporulation regulator WhiA GO:0043937 ARZXY2_RS09085 c74fdc3ae9f1df84e474deccfd4fa4b7 326 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.0E-104 T 09-03-2017 ARZXY2_RS09085 c74fdc3ae9f1df84e474deccfd4fa4b7 326 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 7.1E-24 T 09-03-2017 ARZXY2_RS09085 c74fdc3ae9f1df84e474deccfd4fa4b7 326 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 6.6E-26 T 09-03-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain ARZXY2_RS09085 c74fdc3ae9f1df84e474deccfd4fa4b7 326 Pfam PF02650 WhiA C-terminal HTH domain 221 303 4.8E-19 T 09-03-2017 IPR023054 Sporulation regulator WhiA, C-terminal ARZXY2_RS09455 3300526fd44c6a1f513aa612872aebb1 306 PIRSF PIRSF020623 19 306 3.1E-66 T 09-03-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 ARZXY2_RS09455 3300526fd44c6a1f513aa612872aebb1 306 Pfam PF08223 PaaX-like protein C-terminal domain 116 288 4.2E-45 T 09-03-2017 IPR013225 PaaX-like, C-terminal ARZXY2_RS09455 3300526fd44c6a1f513aa612872aebb1 306 Pfam PF07848 PaaX-like protein 29 93 8.6E-17 T 09-03-2017 IPR012906 PaaX-like, N-terminal ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 ProSitePatterns PS00163 Fumarate lyases signature. 324 333 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 Gene3D G3DSA:1.20.200.10 147 425 1.9E-88 T 09-03-2017 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 11 468 3.2E-207 T 09-03-2017 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 PRINTS PR00149 Fumarate lyase superfamily signature 324 340 4.1E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 PRINTS PR00149 Fumarate lyase superfamily signature 142 160 4.1E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 PRINTS PR00149 Fumarate lyase superfamily signature 187 205 4.1E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 PRINTS PR00149 Fumarate lyase superfamily signature 278 305 4.1E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 Gene3D G3DSA:1.10.275.10 10 146 5.2E-58 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 Pfam PF10415 Fumarase C C-terminus 415 467 1.0E-21 T 09-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 SUPERFAMILY SSF48557 10 465 1.33E-147 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 Gene3D G3DSA:1.10.40.30 426 469 5.6E-22 T 09-03-2017 ARZXY2_RS20455 eb36b637880ca8a326463ea6e82c53a1 471 Pfam PF00206 Lyase 19 349 2.9E-102 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal ARZXY2_RS03420 7f5b9ec54fd9ac817b545b7d43bf74ee 374 SUPERFAMILY SSF55729 35 137 1.66E-11 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03420 7f5b9ec54fd9ac817b545b7d43bf74ee 374 Gene3D G3DSA:3.40.630.30 252 364 5.3E-4 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03420 7f5b9ec54fd9ac817b545b7d43bf74ee 374 Gene3D G3DSA:3.40.630.30 35 136 2.6E-9 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03420 7f5b9ec54fd9ac817b545b7d43bf74ee 374 SUPERFAMILY SSF55729 249 365 2.27E-6 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 Gene3D G3DSA:1.10.10.10 36 179 1.8E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 SUPERFAMILY SSF46785 39 178 2.03E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 Pfam PF12802 MarR family 69 129 3.0E-11 T 09-03-2017 ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 SMART SM00347 61 165 2.7E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 121 2.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17115 dbc0fac4072d95c3a4c2d76343252d04 187 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 141 2.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.1E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.1E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.1E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.1E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.1E-43 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 Pfam PF00248 Aldo/keto reductase family 18 261 1.3E-48 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 PIRSF PIRSF000097 1 272 3.0E-82 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 SUPERFAMILY SSF51430 6 265 3.14E-90 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 Gene3D G3DSA:3.20.20.100 5 269 3.3E-101 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS15010 7c135c8f127630fc294c3088cdc51d68 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 ARZXY2_RS08840 ac83d6d6a00957606d748452499e9a24 398 Gene3D G3DSA:3.40.50.2000 166 375 1.3E-48 T 09-03-2017 ARZXY2_RS08840 ac83d6d6a00957606d748452499e9a24 398 Pfam PF13439 Glycosyltransferase Family 4 15 182 4.5E-30 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS08840 ac83d6d6a00957606d748452499e9a24 398 SUPERFAMILY SSF53756 9 397 2.1E-84 T 09-03-2017 ARZXY2_RS08840 ac83d6d6a00957606d748452499e9a24 398 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 2 397 9.6E-172 T 09-03-2017 IPR011875 Glycogen synthase, corynebacterial KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 ARZXY2_RS08840 ac83d6d6a00957606d748452499e9a24 398 Pfam PF00534 Glycosyl transferases group 1 190 375 5.1E-29 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS15710 2039b10d745a3005cc9dc032daa7c945 512 SUPERFAMILY SSF51011 368 507 4.68E-27 T 09-03-2017 ARZXY2_RS15710 2039b10d745a3005cc9dc032daa7c945 512 SMART SM00813 291 501 2.6E-58 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 ARZXY2_RS15710 2039b10d745a3005cc9dc032daa7c945 512 SUPERFAMILY SSF51445 18 385 8.45E-112 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS15710 2039b10d745a3005cc9dc032daa7c945 512 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 501 3.1E-36 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 ARZXY2_RS15710 2039b10d745a3005cc9dc032daa7c945 512 Gene3D G3DSA:3.20.20.80 36 360 1.2E-38 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS02120 70bb2cdd66bc51bb309f1a2df09fa12e 84 Gene3D G3DSA:3.40.30.10 5 80 2.3E-23 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS02120 70bb2cdd66bc51bb309f1a2df09fa12e 84 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 78 1.2E-13 T 09-03-2017 IPR008554 Glutaredoxin-like ARZXY2_RS02120 70bb2cdd66bc51bb309f1a2df09fa12e 84 SUPERFAMILY SSF52833 3 82 2.24E-16 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Pfam PF00364 Biotin-requiring enzyme 3 75 1.9E-18 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Pfam PF02817 e3 binding domain 143 178 1.4E-11 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Pfam PF02817 e3 binding domain 100 132 2.9E-11 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 SUPERFAMILY SSF52777 228 449 3.74E-57 T 09-03-2017 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 SUPERFAMILY SSF47005 91 135 2.09E-10 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 230 450 5.0E-57 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 SUPERFAMILY SSF51230 2 94 9.68E-25 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Gene3D G3DSA:3.30.559.10 225 450 1.0E-56 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Gene3D G3DSA:2.40.50.100 2 91 1.3E-26 T 09-03-2017 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Gene3D G3DSA:4.10.320.10 92 136 1.3E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 Gene3D G3DSA:4.10.320.10 137 181 7.4E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09895 55aaa2c4e332381fe7c1192b58aa1491 450 SUPERFAMILY SSF47005 138 181 1.06E-9 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 ARZXY2_RS09535 9396180049ea1d3fdbc6fb92efaab859 172 Pfam PF07883 Cupin domain 76 150 2.7E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS09535 9396180049ea1d3fdbc6fb92efaab859 172 Gene3D G3DSA:2.60.120.10 70 153 1.6E-16 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS09535 9396180049ea1d3fdbc6fb92efaab859 172 SUPERFAMILY SSF51182 31 164 1.7E-22 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 SUPERFAMILY SSF102114 26 329 6.93E-66 T 09-03-2017 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 Gene3D G3DSA:3.20.20.70 27 334 7.9E-76 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 Hamap MF_01694 Biotin synthase [bioB]. 27 335 37.101 T 09-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 PIRSF PIRSF001619 12 340 2.6E-102 T 09-03-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 SMART SM00729 67 277 5.5E-37 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 SMART SM00876 242 334 6.4E-27 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 242 331 3.8E-11 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 Pfam PF04055 Radical SAM superfamily 74 231 4.2E-13 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 ARZXY2_RS13855 484de73fe7a582e4cea74e50f4056556 341 TIGRFAM TIGR00433 bioB: biotin synthase 39 332 7.7E-103 T 09-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 ARZXY2_RS10600 95701e25165dd1ebe3e344e4af6434aa 127 SUPERFAMILY SSF54593 10 126 4.03E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS10600 95701e25165dd1ebe3e344e4af6434aa 127 Gene3D G3DSA:3.10.180.10 10 125 6.8E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 Gene3D G3DSA:1.20.120.530 107 241 7.5E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 SMART SM00345 21 80 6.9E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 SMART SM00895 109 231 1.2E-18 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 Gene3D G3DSA:1.10.10.10 20 84 5.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.8E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.8E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 Pfam PF07729 FCD domain 109 230 9.1E-25 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 SUPERFAMILY SSF46785 15 89 1.7E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 SUPERFAMILY SSF48008 107 239 1.39E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS15130 99c4cc75b94a2b09ada0aab92c675f36 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 80 2.9E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 Gene3D G3DSA:1.10.357.10 4 198 3.6E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.2E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.2E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 SUPERFAMILY SSF48498 84 166 1.85E-5 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.2E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS03055 0e1acbaace9112f2b5539775447485cb 212 SUPERFAMILY SSF46689 5 71 2.99E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20475 02b5a4405c40ee6efe7ed8d49db013b6 431 Pfam PF13657 HipA N-terminal domain 7 106 6.0E-23 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 ARZXY2_RS20475 02b5a4405c40ee6efe7ed8d49db013b6 431 Pfam PF07804 HipA-like C-terminal domain 245 394 7.8E-32 T 09-03-2017 IPR012893 HipA-like, C-terminal ARZXY2_RS20475 02b5a4405c40ee6efe7ed8d49db013b6 431 Pfam PF07805 HipA-like N-terminal domain 156 236 8.8E-16 T 09-03-2017 IPR012894 HipA, N-terminal subdomain 2 ARZXY2_RS20475 02b5a4405c40ee6efe7ed8d49db013b6 431 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 7 106 1.9E-27 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 ARZXY2_RS05755 4208de26fa361d19142ed1bfb6b9ecb1 199 Gene3D G3DSA:3.20.19.10 1 186 9.7E-37 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS05755 4208de26fa361d19142ed1bfb6b9ecb1 199 SUPERFAMILY SSF52016 1 188 3.73E-52 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS05755 4208de26fa361d19142ed1bfb6b9ecb1 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 37.784 T 09-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 ARZXY2_RS05755 4208de26fa361d19142ed1bfb6b9ecb1 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 7.4E-55 T 09-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 ARZXY2_RS05755 4208de26fa361d19142ed1bfb6b9ecb1 199 Pfam PF00694 Aconitase C-terminal domain 1 116 2.8E-24 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 Pfam PF03061 Thioesterase superfamily 28 97 2.5E-12 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 Pfam PF03061 Thioesterase superfamily 182 256 4.1E-16 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 Gene3D G3DSA:3.10.129.10 166 301 2.2E-37 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 Gene3D G3DSA:3.10.129.10 9 148 3.8E-36 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 SUPERFAMILY SSF54637 166 306 5.4E-37 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS18910 cfbacc49dad1443856e8f0734afccb88 328 SUPERFAMILY SSF54637 6 149 9.46E-35 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS02295 b1df75aa26ed5b60c7d7b87ec5a73983 248 Pfam PF13350 Tyrosine phosphatase family 26 236 2.1E-31 T 09-03-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type ARZXY2_RS02295 b1df75aa26ed5b60c7d7b87ec5a73983 248 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 135 145 - T 09-03-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 ARZXY2_RS02295 b1df75aa26ed5b60c7d7b87ec5a73983 248 Gene3D G3DSA:3.90.190.10 18 173 3.2E-18 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like ARZXY2_RS02295 b1df75aa26ed5b60c7d7b87ec5a73983 248 SUPERFAMILY SSF52799 14 235 1.41E-31 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like ARZXY2_RS03885 eb057917c585560cb6d0e11525626ec0 687 Pfam PF01757 Acyltransferase family 27 355 3.7E-15 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 ARZXY2_RS03865 e73b5c45c1bf763c3ed70dc54a4a07a2 410 SUPERFAMILY SSF53335 61 229 2.13E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS03865 e73b5c45c1bf763c3ed70dc54a4a07a2 410 Gene3D G3DSA:3.40.50.150 320 358 8.9E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS03865 e73b5c45c1bf763c3ed70dc54a4a07a2 410 Gene3D G3DSA:3.40.50.150 103 172 8.9E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS00640 1611fd4630df13a7e0b3c047b6ae137d 144 Pfam PF04965 Gene 25-like lysozyme 38 126 1.2E-20 T 09-03-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD ARZXY2_RS00640 1611fd4630df13a7e0b3c047b6ae137d 144 Gene3D G3DSA:3.10.450.40 25 141 4.8E-33 T 09-03-2017 ARZXY2_RS00640 1611fd4630df13a7e0b3c047b6ae137d 144 SUPERFAMILY SSF160719 34 139 5.36E-26 T 09-03-2017 ARZXY2_RS18135 a7725ddd64aeaf86009a0048863346ba 131 Pfam PF08570 Protein of unknown function (DUF1761) 8 126 1.8E-28 T 09-03-2017 IPR013879 Protein of unknown function DUF1761 ARZXY2_RS10015 dcc426075027512309ce285daabef506 156 Gene3D G3DSA:2.30.110.10 9 138 5.9E-36 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10015 dcc426075027512309ce285daabef506 156 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 134 1.5E-19 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS10015 dcc426075027512309ce285daabef506 156 SUPERFAMILY SSF50475 9 135 9.16E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 Pfam PF02388 FemAB family 6 411 3.5E-124 T 09-03-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 SUPERFAMILY SSF55729 308 407 4.94E-30 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 SUPERFAMILY SSF55729 165 244 4.94E-30 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 SUPERFAMILY SSF55729 1 162 1.14E-32 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 Gene3D G3DSA:3.40.630.30 1 164 7.0E-39 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 Gene3D G3DSA:3.40.630.30 165 243 1.3E-39 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14355 15b32f55778c9fb087999fbbc195a3d3 439 Gene3D G3DSA:3.40.630.30 307 387 1.3E-39 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 Gene3D G3DSA:3.40.250.10 101 236 7.4E-28 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 SMART SM00450 123 225 9.9E-13 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 Pfam PF12368 Rhodanase C-terminal 230 295 1.8E-16 T 09-03-2017 IPR022111 Rhodanase, C-terminal ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 264 36.09 T 09-03-2017 IPR020936 Uncharacterised protein family UPF0176 ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 Pfam PF00581 Rhodanese-like domain 133 220 8.5E-5 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS01870 c3ab546104c9ad2518b15933e8c7fa4c 298 SUPERFAMILY SSF52821 114 221 1.15E-21 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 SUPERFAMILY SSF51735 9 237 6.57E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 237 5.8E-44 T 09-03-2017 ARZXY2_RS19130 78aa523c20d7801d833434b5224fa5dd 241 Gene3D G3DSA:3.40.50.720 7 238 1.6E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS04295 78948e1e243583c0403f3552b43a3815 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 260 4.5E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04295 78948e1e243583c0403f3552b43a3815 297 Gene3D G3DSA:1.10.3720.10 62 260 3.8E-35 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04295 78948e1e243583c0403f3552b43a3815 297 SUPERFAMILY SSF161098 62 247 5.89E-33 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04295 78948e1e243583c0403f3552b43a3815 297 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 63 154 5.0E-12 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 SUPERFAMILY SSF47823 39 138 4.32E-21 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 Gene3D G3DSA:1.10.150.130 39 139 2.7E-20 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 SUPERFAMILY SSF56349 293 382 1.27E-20 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 SUPERFAMILY SSF56349 138 253 1.27E-20 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 Gene3D G3DSA:1.10.443.10 293 376 6.3E-34 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS06880 c407b7c23e48babfd5162e5de0f37e9f 390 Gene3D G3DSA:1.10.443.10 140 253 6.3E-34 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1130 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF89000 829 997 8.24E-39 T 09-03-2017 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SMART SM00878 343 450 2.4E-55 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:2.40.50.100 1056 1130 3.0E-19 T 09-03-2017 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF52440 1 112 7.91E-40 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF00682 HMGL-like 528 796 5.9E-28 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:3.10.600.10 965 1052 7.6E-30 T 09-03-2017 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF00364 Biotin-requiring enzyme 1073 1129 5.8E-14 T 09-03-2017 IPR000089 Biotin/lipoyl attachment ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:3.40.50.20 1 130 6.2E-46 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 PIRSF PIRSF001594 1 1131 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:3.30.1490.20 131 201 2.1E-24 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF02785 Biotin carboxylase C-terminal domain 343 450 1.4E-34 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF51569 523 832 5.49E-76 T 09-03-2017 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF56059 84 351 1.06E-66 T 09-03-2017 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF51230 1054 1130 1.83E-15 T 09-03-2017 IPR011053 Single hybrid motif ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:3.20.20.70 506 815 4.4E-127 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Gene3D G3DSA:3.30.470.20 205 456 5.4E-98 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 2.3E-38 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 326 1.0E-69 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 SUPERFAMILY SSF51246 338 456 5.07E-38 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS10965 27d72ab28b61a91e2a012a8641565c39 1131 Pfam PF02436 Conserved carboxylase domain 824 1013 5.6E-53 T 09-03-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 129 2.5E-23 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 SUPERFAMILY SSF51735 12 162 1.8E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 Gene3D G3DSA:3.30.360.10 316 368 1.6E-25 T 09-03-2017 ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 Gene3D G3DSA:3.30.360.10 152 275 1.6E-25 T 09-03-2017 ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 Gene3D G3DSA:3.40.50.720 9 151 4.2E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09745 b96fe545c2dbe48be87c9355d9f30458 387 SUPERFAMILY SSF55347 140 339 6.05E-27 T 09-03-2017 ARZXY2_RS15625 efecf8ad52bc57ecca1fe2b06a67fc04 331 SUPERFAMILY SSF161098 32 323 1.7E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15625 efecf8ad52bc57ecca1fe2b06a67fc04 331 Gene3D G3DSA:1.10.3720.10 28 320 4.6E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15625 efecf8ad52bc57ecca1fe2b06a67fc04 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 318 1.1E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05040 41d4bfb1f5cb38edd5a04dcb7cad4a3d 208 SUPERFAMILY SSF46785 10 114 4.87E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05040 41d4bfb1f5cb38edd5a04dcb7cad4a3d 208 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 1.9E-20 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS05040 41d4bfb1f5cb38edd5a04dcb7cad4a3d 208 Gene3D G3DSA:1.10.10.10 4 101 7.8E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 Gene3D G3DSA:3.30.1340.10 1 88 4.1E-27 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 SUPERFAMILY SSF55594 1 90 4.06E-23 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.0E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 PRINTS PR00107 Phosphocarrier protein signature 57 74 1.0E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 PRINTS PR00107 Phosphocarrier protein signature 42 57 1.0E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 86 1.0E-25 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS20195 285b146327bcb9307887568c7de4ab8a 92 Pfam PF00381 PTS HPr component phosphorylation site 3 86 6.6E-27 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PRINTS PR00093 Uricase signature 87 100 5.7E-24 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PRINTS PR00093 Uricase signature 165 177 5.7E-24 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PRINTS PR00093 Uricase signature 52 66 5.7E-24 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PRINTS PR00093 Uricase signature 13 24 5.7E-24 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PRINTS PR00093 Uricase signature 149 165 5.7E-24 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 Pfam PF01014 Uricase 11 133 1.3E-20 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 Pfam PF01014 Uricase 144 280 3.1E-32 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 TIGRFAM TIGR03383 urate_oxi: urate oxidase 7 285 6.1E-116 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 PIRSF PIRSF000241 1 292 1.0E-102 T 09-03-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 ProSitePatterns PS00366 Uricase signature. 149 176 - T 09-03-2017 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 SUPERFAMILY SSF55620 4 131 4.08E-48 T 09-03-2017 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 SUPERFAMILY SSF55620 140 295 3.22E-58 T 09-03-2017 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 179 285 4.0E-52 T 09-03-2017 ARZXY2_RS01585 98a1cde718cde01abefc30e79a5ca4ac 302 Gene3D G3DSA:3.10.270.10 4 289 2.0E-109 T 09-03-2017 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 Gene3D G3DSA:3.40.50.300 3 189 1.7E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 Hamap MF_00235 Adenylate kinase [adk]. 2 187 37.894 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 09-03-2017 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 SUPERFAMILY SSF52540 3 188 8.15E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 PRINTS PR00094 Adenylate kinase signature 33 47 4.6E-32 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 PRINTS PR00094 Adenylate kinase signature 151 165 4.6E-32 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 PRINTS PR00094 Adenylate kinase signature 5 18 4.6E-32 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 PRINTS PR00094 Adenylate kinase signature 82 98 4.6E-32 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 PRINTS PR00094 Adenylate kinase signature 134 149 4.6E-32 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 ARZXY2_RS01485 4116e068c27d9bbd093a0f9c9ba99e72 192 Pfam PF00406 Adenylate kinase 6 164 8.1E-49 T 09-03-2017 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 SMART SM00347 35 135 4.0E-14 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 5.5E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 5.5E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 5.5E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 5.5E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 Pfam PF12802 MarR family 40 99 1.6E-15 T 09-03-2017 ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 Gene3D G3DSA:1.10.10.10 11 150 9.9E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 SUPERFAMILY SSF46785 10 149 3.74E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05560 16e4838c8cedc08951f40b9fb7e4fbb7 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site ARZXY2_RS02780 219926c9d6ee5b473ab0089f44f00bad 694 Pfam PF05787 Bacterial protein of unknown function (DUF839) 105 654 1.6E-155 T 09-03-2017 IPR008557 Protein of unknown function DUF839 ARZXY2_RS02780 219926c9d6ee5b473ab0089f44f00bad 694 SUPERFAMILY SSF63829 339 458 1.24E-8 T 09-03-2017 ARZXY2_RS02780 219926c9d6ee5b473ab0089f44f00bad 694 SUPERFAMILY SSF63829 576 654 1.24E-8 T 09-03-2017 ARZXY2_RS02410 320037cc7898252c54ec8525a2471af3 259 Gene3D G3DSA:1.10.12.10 200 259 7.8E-16 T 09-03-2017 IPR014748 Crontonase, C-terminal ARZXY2_RS02410 320037cc7898252c54ec8525a2471af3 259 SUPERFAMILY SSF52096 2 259 2.25E-63 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS02410 320037cc7898252c54ec8525a2471af3 259 Gene3D G3DSA:3.90.226.10 2 199 8.3E-50 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS02410 320037cc7898252c54ec8525a2471af3 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 258 5.6E-45 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 SMART SM00530 18 73 1.4E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 SUPERFAMILY SSF51182 58 188 1.29E-18 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 Pfam PF07883 Cupin domain 136 184 1.3E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 Pfam PF13560 Helix-turn-helix domain 14 71 1.5E-11 T 09-03-2017 ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 Gene3D G3DSA:1.10.260.40 15 110 1.2E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 Gene3D G3DSA:2.60.120.10 111 188 3.5E-17 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS13990 e4d77d1f65d6215823735a3a80b966b8 191 SUPERFAMILY SSF47413 11 78 1.82E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS02230 4c1435fbdc3231c3b22d89c923baeaca 242 Pfam PF02517 CAAX protease self-immunity 134 226 8.3E-12 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 Gene3D G3DSA:2.115.10.20 30 80 8.1E-5 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 SUPERFAMILY SSF75005 18 362 4.08E-106 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 SMART SM00640 25 478 8.2E-153 T 09-03-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 Gene3D G3DSA:2.120.10.10 81 242 5.2E-10 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 404 478 8.0E-13 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 SUPERFAMILY SSF49899 385 514 2.61E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 25 361 7.3E-96 T 09-03-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal ARZXY2_RS19820 f0174de247cb56e1f72633a6644fdab1 515 Gene3D G3DSA:2.60.120.560 332 498 1.5E-27 T 09-03-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal ARZXY2_RS15875 e520f7256250168393afbd78c5fad057 276 SUPERFAMILY SSF47413 5 63 6.22E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS15875 e520f7256250168393afbd78c5fad057 276 Pfam PF13560 Helix-turn-helix domain 12 67 1.1E-13 T 09-03-2017 ARZXY2_RS15875 e520f7256250168393afbd78c5fad057 276 SMART SM00530 6 64 3.7E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS15875 e520f7256250168393afbd78c5fad057 276 Gene3D G3DSA:1.10.260.40 5 63 2.9E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS02245 afc574289f677bf86435e1339e3b23b2 286 SUPERFAMILY SSF81345 4 261 2.09E-39 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS02245 afc574289f677bf86435e1339e3b23b2 286 Gene3D G3DSA:1.10.3470.10 50 263 5.3E-9 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS02245 afc574289f677bf86435e1339e3b23b2 286 Pfam PF00950 ABC 3 transport family 9 264 8.3E-81 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 Gene3D G3DSA:1.20.1250.20 254 436 1.6E-18 T 09-03-2017 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 Gene3D G3DSA:1.20.1250.20 41 216 2.1E-19 T 09-03-2017 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 SUPERFAMILY SSF103473 19 444 6.02E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 325 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 Pfam PF00083 Sugar (and other) transporter 25 240 6.4E-25 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 Pfam PF00083 Sugar (and other) transporter 260 444 1.0E-12 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS16815 9eacbb61575df3e719dc7acc24f3f22f 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS18455 43b63af6c8ad9ba458fbca4fe64c51ac 274 Gene3D G3DSA:2.40.260.10 113 252 2.8E-22 T 09-03-2017 IPR023365 Sortase domain ARZXY2_RS18455 43b63af6c8ad9ba458fbca4fe64c51ac 274 SUPERFAMILY SSF63817 108 251 1.96E-26 T 09-03-2017 IPR023365 Sortase domain ARZXY2_RS18455 43b63af6c8ad9ba458fbca4fe64c51ac 274 Pfam PF04203 Sortase family 118 247 1.3E-24 T 09-03-2017 IPR005754 Sortase family ARZXY2_RS11950 b858eda009aa7a218480c6b3f4e6fc2e 408 SUPERFAMILY SSF56563 118 403 2.09E-60 T 09-03-2017 ARZXY2_RS11950 b858eda009aa7a218480c6b3f4e6fc2e 408 Pfam PF05065 Phage capsid family 125 401 2.5E-39 T 09-03-2017 IPR024455 Phage capsid ARZXY2_RS11950 b858eda009aa7a218480c6b3f4e6fc2e 408 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 4 401 4.1E-40 T 09-03-2017 IPR006444 Phage major capsid protein, HK97 ARZXY2_RS17875 746b362af317554d3487c748ead4fe61 277 Gene3D G3DSA:3.40.50.1820 2 276 3.9E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17875 746b362af317554d3487c748ead4fe61 277 SUPERFAMILY SSF53474 2 275 1.23E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17875 746b362af317554d3487c748ead4fe61 277 Pfam PF12697 Alpha/beta hydrolase family 30 230 4.0E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS11380 c85febefec8b9a90d20127d3007c242a 180 Hamap MF_01114 Regulatory protein RecX [recX]. 16 176 14.22 T 09-03-2017 IPR003783 Regulatory protein RecX GO:0006282 ARZXY2_RS11380 c85febefec8b9a90d20127d3007c242a 180 Gene3D G3DSA:1.10.10.10 26 68 9.2E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11380 c85febefec8b9a90d20127d3007c242a 180 Pfam PF02631 RecX family 47 171 6.2E-28 T 09-03-2017 IPR003783 Regulatory protein RecX GO:0006282 ARZXY2_RS11380 c85febefec8b9a90d20127d3007c242a 180 Gene3D G3DSA:1.10.10.10 71 114 3.3E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08860 1f4365ac3864e53d6540458a8e834933 308 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 295 7.9E-79 T 09-03-2017 IPR007296 Domain of unknown function DUF403 ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 6 558 31.594 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 Gene3D G3DSA:3.40.50.970 378 544 1.1E-14 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 Gene3D G3DSA:3.40.50.970 12 184 1.7E-43 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 176 7.0E-28 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 SUPERFAMILY SSF52518 12 186 1.08E-28 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 PIRSF PIRSF004983 4 564 1.1E-122 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 13 428 7.2E-109 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 ARZXY2_RS02785 782dff72b0744729ab717e910d381f39 568 SUPERFAMILY SSF52518 397 545 1.9E-16 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02240 e392e8bccb75ae056ba013f9045fcead 244 SUPERFAMILY SSF52540 4 227 2.93E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02240 e392e8bccb75ae056ba013f9045fcead 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02240 e392e8bccb75ae056ba013f9045fcead 244 Pfam PF00005 ABC transporter 21 169 1.3E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS02240 e392e8bccb75ae056ba013f9045fcead 244 Gene3D G3DSA:3.40.50.300 2 234 1.6E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02240 e392e8bccb75ae056ba013f9045fcead 244 SMART SM00382 30 218 2.9E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS10895 cdfcfd65bf60d5c810aa68c8e833da0a 122 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 3.2E-27 T 09-03-2017 IPR021401 Protein of unknown function DUF3040 ARZXY2_RS06080 75ed3c66d8e11bf7006e99b880469f32 306 SUPERFAMILY SSF103481 59 159 4.84E-13 T 09-03-2017 ARZXY2_RS06080 75ed3c66d8e11bf7006e99b880469f32 306 Pfam PF00892 EamA-like transporter family 162 295 2.6E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS06080 75ed3c66d8e11bf7006e99b880469f32 306 Pfam PF00892 EamA-like transporter family 28 154 5.3E-18 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS06080 75ed3c66d8e11bf7006e99b880469f32 306 SUPERFAMILY SSF103481 194 300 1.83E-13 T 09-03-2017 ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 ProSitePatterns PS01229 Hypothetical cof family signature 2. 231 253 - T 09-03-2017 ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 SUPERFAMILY SSF56784 20 280 2.2E-53 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 23 277 9.5E-45 T 09-03-2017 IPR000150 Cof protein GO:0016787 ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 Gene3D G3DSA:3.40.50.1000 17 92 5.3E-47 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 Gene3D G3DSA:3.40.50.1000 186 281 5.3E-47 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 23 250 2.0E-21 T 09-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ARZXY2_RS18145 dd1f7ff694c730710d9cc7d054e9bcbc 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 24 277 1.1E-48 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS02350 12b3411f63eda8af628d7d85bfd47676 127 Gene3D G3DSA:3.40.1680.10 8 79 4.5E-34 T 09-03-2017 ARZXY2_RS02350 12b3411f63eda8af628d7d85bfd47676 127 Gene3D G3DSA:3.40.970.30 80 124 1.9E-26 T 09-03-2017 ARZXY2_RS02350 12b3411f63eda8af628d7d85bfd47676 127 Pfam PF11964 SpoIIAA-like 35 124 2.3E-5 T 09-03-2017 IPR021866 SpoIIAA-like ARZXY2_RS14600 4177b981bed581741928cd3ea3591e05 295 Gene3D G3DSA:1.20.1330.10 54 250 3.8E-28 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS14600 4177b981bed581741928cd3ea3591e05 295 SUPERFAMILY SSF64518 1 295 2.62E-60 T 09-03-2017 ARZXY2_RS14600 4177b981bed581741928cd3ea3591e05 295 Pfam PF00700 Bacterial flagellin C-terminal helical region 212 294 1.0E-9 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS14600 4177b981bed581741928cd3ea3591e05 295 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 189 4.1E-48 T 09-03-2017 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 ARZXY2_RS14600 4177b981bed581741928cd3ea3591e05 295 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 2.5E-25 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS05215 dbf016820b0b7a5ee388c3ff1381a876 370 Pfam PF00953 Glycosyl transferase family 4 81 243 2.2E-36 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 ARZXY2_RS05215 dbf016820b0b7a5ee388c3ff1381a876 370 ProSitePatterns PS01348 MraY family signature 2. 156 167 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS02445 ac8324f6b273a67f84e4c7de7fd11aa9 297 Gene3D G3DSA:3.90.550.10 9 284 1.8E-70 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02445 ac8324f6b273a67f84e4c7de7fd11aa9 297 Pfam PF00483 Nucleotidyl transferase 10 274 3.1E-27 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ARZXY2_RS02445 ac8324f6b273a67f84e4c7de7fd11aa9 297 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 1.1E-103 T 09-03-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 ARZXY2_RS02445 ac8324f6b273a67f84e4c7de7fd11aa9 297 SUPERFAMILY SSF53448 6 278 7.09E-63 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 Gene3D G3DSA:1.10.10.10 1 64 4.7E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 Pfam PF13280 WYL domain 142 301 2.2E-26 T 09-03-2017 IPR026881 WYL domain ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 SMART SM00420 7 63 0.0042 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 Pfam PF08279 HTH domain 7 62 2.3E-15 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 ARZXY2_RS05120 6cde9c67e50376e37a609a81a33f05d9 330 SUPERFAMILY SSF46785 5 63 1.82E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 Gene3D G3DSA:3.30.70.20 3 71 8.5E-17 T 09-03-2017 ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 SUPERFAMILY SSF54862 3 77 4.19E-18 T 09-03-2017 ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.0E-15 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.0E-15 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.0E-15 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 ARZXY2_RS13915 fb01b26221a22b26016e82d2c0cd8c7a 103 Pfam PF00037 4Fe-4S binding domain 34 56 4.1E-7 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain ARZXY2_RS03960 66190898b833f1b9c6899cb1ef3a4a33 88 SMART SM00834 2 41 2.8E-11 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain ARZXY2_RS03960 66190898b833f1b9c6899cb1ef3a4a33 88 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 7.3E-18 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain ARZXY2_RS03960 66190898b833f1b9c6899cb1ef3a4a33 88 Pfam PF09723 Zinc ribbon domain 2 39 9.0E-14 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain ARZXY2_RS07790 027e838348519d1320febebc79107b72 81 SUPERFAMILY SSF52833 1 72 2.04E-19 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07790 027e838348519d1320febebc79107b72 81 Pfam PF00462 Glutaredoxin 3 61 8.4E-16 T 09-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 ARZXY2_RS07790 027e838348519d1320febebc79107b72 81 Gene3D G3DSA:3.40.30.10 1 74 7.8E-30 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07790 027e838348519d1320febebc79107b72 81 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 9.3E-33 T 09-03-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 Pfam PF00764 Arginosuccinate synthase 6 391 2.7E-180 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 Gene3D G3DSA:3.40.50.620 3 173 4.5E-54 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 8.7E-147 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 52.093 T 09-03-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 SUPERFAMILY SSF69864 171 392 1.12E-85 T 09-03-2017 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 SUPERFAMILY SSF52402 3 165 1.01E-41 T 09-03-2017 ARZXY2_RS11200 867d209fc53ccfbdaede4bef0fbb3073 401 Gene3D G3DSA:3.90.1260.10 174 393 3.4E-84 T 09-03-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 ARZXY2_RS10370 c9681c7d5ace931f068fa15022231eb1 75 Pfam PF14013 MT0933-like antitoxin protein 10 56 6.0E-13 T 09-03-2017 IPR028037 Antitoxin Rv0909/MT0933 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 SMART SM00155 223 250 0.3 T 09-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 SMART SM00155 403 430 3.5E-4 T 09-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 Gene3D G3DSA:3.30.870.10 114 323 2.5E-38 T 09-03-2017 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 Pfam PF13091 PLD-like domain 331 447 2.0E-24 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 Pfam PF13091 PLD-like domain 139 251 3.5E-12 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 SUPERFAMILY SSF56024 109 318 5.61E-42 T 09-03-2017 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 SUPERFAMILY SSF56024 278 473 2.18E-47 T 09-03-2017 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 23 486 1.2E-99 T 09-03-2017 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 Gene3D G3DSA:3.30.870.10 324 467 5.0E-36 T 09-03-2017 ARZXY2_RS00490 42289e00f4eb1ecee69b3738c723df54 490 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 64 2.5E-5 T 09-03-2017 IPR027379 Cardiolipin synthase N-terminal ARZXY2_RS00850 5775e4c37e2a348f197b16d9561255b4 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 137 3.2E-25 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS00850 5775e4c37e2a348f197b16d9561255b4 334 SUPERFAMILY SSF50129 17 187 2.13E-41 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00850 5775e4c37e2a348f197b16d9561255b4 334 Gene3D G3DSA:3.90.180.10 20 170 8.6E-40 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS00850 5775e4c37e2a348f197b16d9561255b4 334 Gene3D G3DSA:3.40.50.720 171 281 1.3E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00850 5775e4c37e2a348f197b16d9561255b4 334 SUPERFAMILY SSF51735 146 297 6.88E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10495 55ebfc94c42d6c4e0e4177f8c020f404 75 SUPERFAMILY SSF47789 17 70 1.83E-6 T 09-03-2017 ARZXY2_RS10495 55ebfc94c42d6c4e0e4177f8c020f404 75 Gene3D G3DSA:1.10.150.20 17 70 1.5E-4 T 09-03-2017 ARZXY2_RS04025 6e403ea420f644d5c90aeb558efcce54 176 Pfam PF00210 Ferritin-like domain 8 143 1.1E-34 T 09-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 ARZXY2_RS04025 6e403ea420f644d5c90aeb558efcce54 176 SUPERFAMILY SSF47240 1 146 2.64E-41 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS04025 6e403ea420f644d5c90aeb558efcce54 176 Gene3D G3DSA:1.20.1260.10 2 155 2.7E-41 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS14235 188bde03809740bf94d0667c570f9b78 276 Gene3D G3DSA:2.70.70.10 134 276 8.5E-47 T 09-03-2017 ARZXY2_RS14235 188bde03809740bf94d0667c570f9b78 276 SUPERFAMILY SSF51261 145 276 1.15E-51 T 09-03-2017 IPR011055 Duplicated hybrid motif ARZXY2_RS14235 188bde03809740bf94d0667c570f9b78 276 Pfam PF01551 Peptidase family M23 177 272 6.9E-31 T 09-03-2017 IPR016047 Peptidase M23 ARZXY2_RS05305 35e5d6a39c772dfff8b21566afdf8a29 264 Gene3D G3DSA:3.40.50.1820 31 241 2.1E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS05305 35e5d6a39c772dfff8b21566afdf8a29 264 SUPERFAMILY SSF53474 25 241 8.25E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS11605 2def94994003175c774fe9a9f483d04a 292 Pfam PF13312 Domain of unknown function (DUF4081) 62 165 5.1E-31 T 09-03-2017 IPR025289 Domain of unknown function DUF4081 ARZXY2_RS11605 2def94994003175c774fe9a9f483d04a 292 SUPERFAMILY SSF55729 20 287 1.03E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS11605 2def94994003175c774fe9a9f483d04a 292 Gene3D G3DSA:3.40.630.30 158 287 8.6E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 Pfam PF00772 DnaB-like helicase N terminal domain 4 96 5.6E-10 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 SUPERFAMILY SSF52540 160 334 1.83E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 Gene3D G3DSA:1.10.860.10 4 96 2.5E-10 T 09-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 Gene3D G3DSA:3.40.50.300 160 369 4.4E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 Pfam PF13481 AAA domain 155 322 1.8E-16 T 09-03-2017 ARZXY2_RS11880 44e99b4f9a4092ad899f016a2693e22e 411 SUPERFAMILY SSF48024 3 103 5.1E-12 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 ARZXY2_RS07240 81e64e0043ee8513e25aa755a43f6798 718 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 20 198 6.9E-37 T 09-03-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal ARZXY2_RS07240 81e64e0043ee8513e25aa755a43f6798 718 Pfam PF06202 Amylo-alpha-1,6-glucosidase 349 630 3.1E-6 T 09-03-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 ARZXY2_RS07240 81e64e0043ee8513e25aa755a43f6798 718 SUPERFAMILY SSF48208 267 638 7.23E-79 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 SUPERFAMILY SSF46785 4 115 1.82E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 Gene3D G3DSA:1.10.10.10 5 89 2.0E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.4E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.4E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.4E-5 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 SUPERFAMILY SSF53850 95 297 1.92E-37 T 09-03-2017 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 Gene3D G3DSA:3.40.190.10 93 175 7.1E-18 T 09-03-2017 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 Gene3D G3DSA:3.40.190.10 176 267 9.9E-17 T 09-03-2017 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.3E-17 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15655 43ceb685bc8d94a0f58e1165c85f7ef9 299 Pfam PF03466 LysR substrate binding domain 92 297 2.0E-42 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS15455 f23eb8ef17a8c299d04b19b6f88a9a0e 238 Gene3D G3DSA:3.10.180.10 18 87 1.8E-4 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS05555 2fc46566f599f73ed379f609ad9983c1 268 Pfam PF01841 Transglutaminase-like superfamily 125 210 9.8E-19 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS05555 2fc46566f599f73ed379f609ad9983c1 268 SUPERFAMILY SSF54001 110 237 4.63E-27 T 09-03-2017 ARZXY2_RS05555 2fc46566f599f73ed379f609ad9983c1 268 Gene3D G3DSA:3.90.260.10 156 214 3.8E-6 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS05555 2fc46566f599f73ed379f609ad9983c1 268 SMART SM00460 152 212 2.7E-14 T 09-03-2017 IPR002931 Transglutaminase-like ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 Gene3D G3DSA:3.40.50.300 487 592 3.6E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 Gene3D G3DSA:3.40.50.300 186 320 3.6E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 Gene3D G3DSA:3.40.50.300 593 715 7.8E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 Pfam PF13245 Part of AAA domain 199 278 5.4E-14 T 09-03-2017 ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 SUPERFAMILY SSF52540 186 266 7.25E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 SUPERFAMILY SSF52540 474 716 7.25E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13600 492573a2087ab129aa1718f2a69b9429 717 SUPERFAMILY SSF52540 363 380 7.25E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS13780 69512d7fd138d6696865dc70629185ba 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 102 1.3E-23 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 ARZXY2_RS13780 69512d7fd138d6696865dc70629185ba 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 91 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 ARZXY2_RS13780 69512d7fd138d6696865dc70629185ba 150 SUPERFAMILY SSF53927 11 147 7.86E-38 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 ARZXY2_RS13780 69512d7fd138d6696865dc70629185ba 150 Gene3D G3DSA:3.40.140.10 5 139 1.2E-37 T 09-03-2017 ARZXY2_RS09615 c2d99ce2f506dcd2981e085e179379eb 284 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 13 277 3.7E-60 T 09-03-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 ARZXY2_RS09615 c2d99ce2f506dcd2981e085e179379eb 284 Gene3D G3DSA:3.60.130.10 9 283 1.1E-85 T 09-03-2017 ARZXY2_RS09615 c2d99ce2f506dcd2981e085e179379eb 284 SUPERFAMILY SSF51197 11 283 2.66E-83 T 09-03-2017 ARZXY2_RS20345 288aa4a33cf4f967aad86d59b39b9b67 214 SUPERFAMILY SSF103025 87 208 3.73E-11 T 09-03-2017 ARZXY2_RS20345 288aa4a33cf4f967aad86d59b39b9b67 214 Pfam PF04268 Sarcosine oxidase, gamma subunit family 72 207 2.3E-25 T 09-03-2017 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 ARZXY2_RS04055 6e6e50d5caf1d2a1ea4ee5c17eccc0e6 212 Pfam PF06736 Protein of unknown function (DUF1211) 15 106 4.6E-24 T 09-03-2017 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 ARZXY2_RS02185 8f7fe53b55b6080e356ec460c66df4ef 644 SUPERFAMILY SSF52540 21 270 1.95E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02185 8f7fe53b55b6080e356ec460c66df4ef 644 Gene3D G3DSA:3.40.50.300 31 84 2.6E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02185 8f7fe53b55b6080e356ec460c66df4ef 644 Gene3D G3DSA:3.40.50.300 156 263 2.6E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02185 8f7fe53b55b6080e356ec460c66df4ef 644 Pfam PF00350 Dynamin family 44 212 1.6E-20 T 09-03-2017 IPR022812 Dynamin superfamily ARZXY2_RS16405 a8c27107d559f0e37f407c3cc343a47c 432 Gene3D G3DSA:3.30.590.10 102 417 1.0E-64 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 ARZXY2_RS16405 a8c27107d559f0e37f407c3cc343a47c 432 SMART SM01230 99 345 1.6E-61 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS16405 a8c27107d559f0e37f407c3cc343a47c 432 Pfam PF16952 Glutamine synthetase N-terminal domain 10 98 7.4E-12 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS16405 a8c27107d559f0e37f407c3cc343a47c 432 SUPERFAMILY SSF55931 100 423 1.24E-69 T 09-03-2017 ARZXY2_RS16405 a8c27107d559f0e37f407c3cc343a47c 432 Pfam PF00120 Glutamine synthetase, catalytic domain 100 418 1.2E-64 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 Pfam PF00221 Aromatic amino acid lyase 19 485 2.5E-175 T 09-03-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 11 525 2.2E-195 T 09-03-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 Gene3D G3DSA:1.10.275.10 5 211 1.8E-70 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 SUPERFAMILY SSF48557 5 518 7.3E-174 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 Gene3D G3DSA:1.20.200.10 212 525 3.3E-112 T 09-03-2017 ARZXY2_RS16785 74c888b275515fd98e0797a056b58b8e 530 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 146 162 - T 09-03-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 Gene3D G3DSA:3.40.50.720 4 139 5.7E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 SUPERFAMILY SSF51735 4 153 2.69E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 120 1.6E-16 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 Gene3D G3DSA:3.30.360.10 336 384 5.1E-7 T 09-03-2017 ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 Gene3D G3DSA:3.30.360.10 140 301 5.1E-7 T 09-03-2017 ARZXY2_RS01765 3a4fbe5ca22d4cc0a4822efcd687d041 399 SUPERFAMILY SSF55347 126 271 4.25E-5 T 09-03-2017 ARZXY2_RS05760 1d0f2c531a025f5dbfa4b626d2dea775 441 Gene3D G3DSA:3.65.10.10 22 225 7.2E-51 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05760 1d0f2c531a025f5dbfa4b626d2dea775 441 Gene3D G3DSA:3.65.10.10 226 435 3.2E-47 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05760 1d0f2c531a025f5dbfa4b626d2dea775 441 SUPERFAMILY SSF55205 4 437 2.45E-108 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 ARZXY2_RS05760 1d0f2c531a025f5dbfa4b626d2dea775 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 428 2.9E-57 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 ARZXY2_RS05760 1d0f2c531a025f5dbfa4b626d2dea775 441 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 434 2.5E-125 T 09-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS15735 10dd9d28248fa6c03f6fca659625f030 229 SUPERFAMILY SSF48498 87 175 1.09E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS15735 10dd9d28248fa6c03f6fca659625f030 229 Gene3D G3DSA:1.10.357.10 11 181 5.1E-28 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS15735 10dd9d28248fa6c03f6fca659625f030 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 65 5.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS15735 10dd9d28248fa6c03f6fca659625f030 229 SUPERFAMILY SSF46689 12 82 3.89E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS07395 e3eee4c3ab89e7077617d33ed2540e9e 355 SUPERFAMILY SSF51735 136 318 1.39E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07395 e3eee4c3ab89e7077617d33ed2540e9e 355 Gene3D G3DSA:3.40.50.720 138 318 4.4E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07395 e3eee4c3ab89e7077617d33ed2540e9e 355 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 146 317 4.4E-46 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS07395 e3eee4c3ab89e7077617d33ed2540e9e 355 SMART SM01002 168 290 0.0071 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain ARZXY2_RS07395 e3eee4c3ab89e7077617d33ed2540e9e 355 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 257 273 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS11595 17504229f1e1fc9ca8147f59c9040a0a 251 PIRSF PIRSF006648 2 251 1.5E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS11595 17504229f1e1fc9ca8147f59c9040a0a 251 Pfam PF01061 ABC-2 type transporter 16 214 1.8E-30 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS12815 f98cf83836095f175eb769565d805f85 298 SUPERFAMILY SSF51556 36 295 3.03E-69 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS12815 f98cf83836095f175eb769565d805f85 298 Gene3D G3DSA:3.20.20.140 29 295 3.3E-75 T 09-03-2017 ARZXY2_RS12815 f98cf83836095f175eb769565d805f85 298 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 38 294 4.7E-65 T 09-03-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 ARZXY2_RS12815 f98cf83836095f175eb769565d805f85 298 Pfam PF01026 TatD related DNase 39 294 7.3E-62 T 09-03-2017 IPR001130 TatD family GO:0016788 ARZXY2_RS12815 f98cf83836095f175eb769565d805f85 298 PIRSF PIRSF005902 9 298 2.1E-68 T 09-03-2017 IPR001130 TatD family GO:0016788 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 SUPERFAMILY SSF116726 147 216 2.49E-13 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 Gene3D G3DSA:3.30.70.1450 148 214 1.2E-10 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 Gene3D G3DSA:3.40.50.720 2 145 1.0E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 SUPERFAMILY SSF51735 2 145 8.99E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 Pfam PF02080 TrkA-C domain 149 216 5.7E-13 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 Pfam PF02254 TrkA-N domain 3 118 9.7E-26 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 4.7E-12 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.7E-12 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.7E-12 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS10535 4dd2a2442b3cff98fcd9f791e1b9b1bf 245 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 4.7E-12 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 ARZXY2_RS08185 b377659ebb9aea5899ee8ea2883a2d87 369 SUPERFAMILY SSF53756 16 352 8.9E-46 T 09-03-2017 ARZXY2_RS08185 b377659ebb9aea5899ee8ea2883a2d87 369 Gene3D G3DSA:3.40.50.2000 179 326 1.1E-13 T 09-03-2017 ARZXY2_RS08185 b377659ebb9aea5899ee8ea2883a2d87 369 Pfam PF00534 Glycosyl transferases group 1 179 316 8.7E-18 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS13300 507f407e5bf38fc0cca0037da131f4cd 173 Gene3D G3DSA:2.160.10.10 3 170 4.1E-44 T 09-03-2017 ARZXY2_RS13300 507f407e5bf38fc0cca0037da131f4cd 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 8.0E-8 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS13300 507f407e5bf38fc0cca0037da131f4cd 173 SUPERFAMILY SSF51161 3 168 1.66E-44 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS08465 3dec60b83610e70a699449dbcff2e763 80 SUPERFAMILY SSF48498 4 73 1.03E-11 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS08465 3dec60b83610e70a699449dbcff2e763 80 Gene3D G3DSA:1.10.357.10 3 75 8.6E-11 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS12130 afbadb0e8838627db41b953fb53c5ac4 208 Pfam PF01066 CDP-alcohol phosphatidyltransferase 23 87 1.8E-15 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS12130 afbadb0e8838627db41b953fb53c5ac4 208 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 65 87 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS12130 afbadb0e8838627db41b953fb53c5ac4 208 PIRSF PIRSF000847 18 203 4.8E-39 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 ARZXY2_RS20440 89752b556c26dff1cebf852726b7a7ef 306 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 282 3.8E-65 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS20440 89752b556c26dff1cebf852726b7a7ef 306 Gene3D G3DSA:3.90.850.10 72 283 1.6E-79 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS20440 89752b556c26dff1cebf852726b7a7ef 306 SUPERFAMILY SSF56529 69 283 5.76E-72 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09735 760452257248ec7319cee28a8c6cbd4a 451 Gene3D G3DSA:3.40.605.10 3 251 6.6E-76 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09735 760452257248ec7319cee28a8c6cbd4a 451 Gene3D G3DSA:3.40.309.10 252 427 3.6E-48 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS09735 760452257248ec7319cee28a8c6cbd4a 451 Pfam PF00171 Aldehyde dehydrogenase family 3 445 1.3E-121 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09735 760452257248ec7319cee28a8c6cbd4a 451 SUPERFAMILY SSF53720 3 447 7.46E-126 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS18660 d21d8b9757e34370635f53d2ab7ebb26 133 Gene3D G3DSA:1.10.10.10 7 122 8.8E-46 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS18660 d21d8b9757e34370635f53d2ab7ebb26 133 Pfam PF01638 HxlR-like helix-turn-helix 24 110 4.6E-26 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type ARZXY2_RS18660 d21d8b9757e34370635f53d2ab7ebb26 133 SUPERFAMILY SSF46785 9 122 9.25E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02885 7349a1107dcb0d999b01118d4822d11e 185 Pfam PF01872 RibD C-terminal domain 4 177 2.6E-19 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS02885 7349a1107dcb0d999b01118d4822d11e 185 SUPERFAMILY SSF53597 3 183 4.32E-28 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS02885 7349a1107dcb0d999b01118d4822d11e 185 Gene3D G3DSA:3.40.430.10 4 183 1.2E-23 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 484 593 1.2E-19 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 Pfam PF00672 HAMP domain 291 359 7.1E-13 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SUPERFAMILY SSF47384 353 437 8.24E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SMART SM00388 370 437 1.9E-18 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 Gene3D G3DSA:3.30.565.10 424 593 6.0E-37 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SMART SM00387 483 594 2.9E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 Gene3D G3DSA:1.10.287.130 361 423 8.7E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SMART SM00304 310 362 1.4E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 Pfam PF00512 His Kinase A (phospho-acceptor) domain 370 437 9.7E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SUPERFAMILY SSF55874 426 593 4.45E-39 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 SUPERFAMILY SSF158472 310 361 2.09E-7 T 09-03-2017 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 572 3.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 3.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 547 3.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS04755 1f15965aea9466e30b3a7e8f5aa91cff 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 591 3.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS19570 ce58de38c7f80a42f8ea2fd673390663 456 SUPERFAMILY SSF103473 26 449 4.05E-83 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS19570 ce58de38c7f80a42f8ea2fd673390663 456 Pfam PF07690 Major Facilitator Superfamily 47 414 1.6E-52 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS19570 ce58de38c7f80a42f8ea2fd673390663 456 PIRSF PIRSF002808 27 448 6.6E-35 T 09-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS19570 ce58de38c7f80a42f8ea2fd673390663 456 Gene3D G3DSA:1.20.1250.20 260 446 3.8E-22 T 09-03-2017 ARZXY2_RS19570 ce58de38c7f80a42f8ea2fd673390663 456 Gene3D G3DSA:1.20.1250.20 34 231 2.6E-51 T 09-03-2017 ARZXY2_RS11565 1894384d3a89d82b4de59c87ae86c55d 203 SUPERFAMILY SSF74942 110 184 7.98E-6 T 09-03-2017 IPR028998 Ribosome maturation factor RimP, C-terminal ARZXY2_RS11565 1894384d3a89d82b4de59c87ae86c55d 203 Pfam PF02576 Putative ribosome maturation factor RimP 33 179 4.0E-27 T 09-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 ARZXY2_RS11565 1894384d3a89d82b4de59c87ae86c55d 203 Gene3D G3DSA:3.30.300.70 26 106 9.4E-16 T 09-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal ARZXY2_RS11565 1894384d3a89d82b4de59c87ae86c55d 203 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 27 184 20.651 T 09-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 ARZXY2_RS11565 1894384d3a89d82b4de59c87ae86c55d 203 SUPERFAMILY SSF75420 23 108 8.24E-14 T 09-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal ARZXY2_RS13615 5cf7ba3b443c518aa89a76e2f864e9e2 459 Gene3D G3DSA:1.20.1250.20 265 452 2.0E-22 T 09-03-2017 ARZXY2_RS13615 5cf7ba3b443c518aa89a76e2f864e9e2 459 SUPERFAMILY SSF103473 251 453 2.62E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13615 5cf7ba3b443c518aa89a76e2f864e9e2 459 SUPERFAMILY SSF103473 5 200 2.62E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13615 5cf7ba3b443c518aa89a76e2f864e9e2 459 Gene3D G3DSA:1.20.1250.20 12 189 2.0E-31 T 09-03-2017 ARZXY2_RS13615 5cf7ba3b443c518aa89a76e2f864e9e2 459 Pfam PF07690 Major Facilitator Superfamily 15 411 4.4E-51 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS01890 f2abbeeb291e5c638688743b4e2ba9ce 212 SUPERFAMILY SSF46785 27 156 1.3E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01890 f2abbeeb291e5c638688743b4e2ba9ce 212 Gene3D G3DSA:1.10.10.10 28 88 3.8E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01890 f2abbeeb291e5c638688743b4e2ba9ce 212 Pfam PF12840 Helix-turn-helix domain 31 83 2.0E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01890 f2abbeeb291e5c638688743b4e2ba9ce 212 SMART SM00418 30 135 0.0019 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS16415 8088801bc2d14e96ddecbfe8fbdaf3ad 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 292 2.4E-38 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 SUPERFAMILY SSF54373 212 319 2.51E-12 T 09-03-2017 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 SUPERFAMILY SSF51905 319 364 1.17E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 SUPERFAMILY SSF51905 3 213 1.17E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Gene3D G3DSA:3.50.50.60 142 204 4.8E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Gene3D G3DSA:3.50.50.60 2 57 4.8E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Gene3D G3DSA:3.50.50.60 322 362 4.8E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Gene3D G3DSA:3.30.9.10 58 141 1.4E-28 T 09-03-2017 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Gene3D G3DSA:3.30.9.10 210 319 1.4E-28 T 09-03-2017 ARZXY2_RS13380 46b6e67c889cd717858f3ce92989938b 369 Pfam PF01266 FAD dependent oxidoreductase 4 354 3.9E-49 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 ARZXY2_RS13255 e4ef02d46bcd16999e399d5a700ec77e 277 SUPERFAMILY SSF56219 10 276 5.1E-66 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS13255 e4ef02d46bcd16999e399d5a700ec77e 277 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 10 273 1.4E-56 T 09-03-2017 ARZXY2_RS13255 e4ef02d46bcd16999e399d5a700ec77e 277 Gene3D G3DSA:3.60.10.10 10 276 4.1E-78 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS13255 e4ef02d46bcd16999e399d5a700ec77e 277 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 268 1.3E-20 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS13255 e4ef02d46bcd16999e399d5a700ec77e 277 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 10 275 4.5E-60 T 09-03-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 ARZXY2_RS05500 76507f274ff27af3e98341c34a7ef501 465 ProSitePatterns PS00218 Amino acid permeases signature. 48 78 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS05500 76507f274ff27af3e98341c34a7ef501 465 Pfam PF00324 Amino acid permease 24 422 7.8E-92 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS05500 76507f274ff27af3e98341c34a7ef501 465 PIRSF PIRSF006060 1 463 1.0E-76 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS02510 dbea4f05ed8a7288ee3fc905d553c48e 166 Gene3D G3DSA:2.160.10.10 11 159 3.7E-26 T 09-03-2017 ARZXY2_RS02510 dbea4f05ed8a7288ee3fc905d553c48e 166 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 117 145 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 ARZXY2_RS02510 dbea4f05ed8a7288ee3fc905d553c48e 166 PIRSF PIRSF000441 4 163 3.5E-40 T 09-03-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 ARZXY2_RS02510 dbea4f05ed8a7288ee3fc905d553c48e 166 SUPERFAMILY SSF51161 26 159 5.41E-34 T 09-03-2017 IPR011004 Trimeric LpxA-like ARZXY2_RS02510 dbea4f05ed8a7288ee3fc905d553c48e 166 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 142 2.8E-6 T 09-03-2017 IPR001451 Hexapeptide repeat ARZXY2_RS14405 2ed3968c775d33c1e6fe1fb44bd0a751 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.8E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS14405 2ed3968c775d33c1e6fe1fb44bd0a751 179 Gene3D G3DSA:1.10.357.10 7 158 1.7E-24 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS14405 2ed3968c775d33c1e6fe1fb44bd0a751 179 SUPERFAMILY SSF46689 4 76 9.75E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS14405 2ed3968c775d33c1e6fe1fb44bd0a751 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.6E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS14405 2ed3968c775d33c1e6fe1fb44bd0a751 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.6E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS01560 4b3eb96695d0126f671e4fb8ee5a84e8 420 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 180 287 8.6E-5 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS01560 4b3eb96695d0126f671e4fb8ee5a84e8 420 SUPERFAMILY SSF51621 89 334 1.02E-13 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS01560 4b3eb96695d0126f671e4fb8ee5a84e8 420 Gene3D G3DSA:3.20.20.60 91 299 5.3E-12 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.949 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 SUPERFAMILY SSF50193 2 122 4.45E-50 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 09-03-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 SMART SM01374 1 122 1.2E-85 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 Gene3D G3DSA:2.40.150.20 2 122 7.9E-53 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.1E-57 T 09-03-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 ARZXY2_RS03545 12ae1676e5dd96cb93e4f1e4d53b9d2e 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 2.4E-53 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 ARZXY2_RS02015 2d874ff7ccf47862ef854118b1750287 310 Gene3D G3DSA:1.10.3720.10 35 298 6.5E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02015 2d874ff7ccf47862ef854118b1750287 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 298 1.1E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02015 2d874ff7ccf47862ef854118b1750287 310 SUPERFAMILY SSF161098 37 310 5.49E-73 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01710 2f4a663eaefe797852d8cff36c2e486e 315 SUPERFAMILY SSF56300 54 272 3.61E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS01710 2f4a663eaefe797852d8cff36c2e486e 315 Gene3D G3DSA:3.60.21.10 59 259 1.9E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS01710 2f4a663eaefe797852d8cff36c2e486e 315 Pfam PF00149 Calcineurin-like phosphoesterase 60 246 2.3E-9 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 Gene3D G3DSA:3.40.640.10 47 272 4.1E-68 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 229 253 9.4E-14 T 09-03-2017 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 9.4E-14 T 09-03-2017 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 9.4E-14 T 09-03-2017 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 9.4E-14 T 09-03-2017 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 Gene3D G3DSA:3.90.1150.10 273 383 3.1E-27 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 SUPERFAMILY SSF53383 4 383 1.32E-100 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS11535 94ca0f6976f1b5c9408577f0f2005c8f 387 Pfam PF00155 Aminotransferase class I and II 33 377 1.8E-60 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS17595 ad802fe986df2f4886edfbdd9854d649 399 Gene3D G3DSA:3.90.1150.10 277 398 7.9E-22 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS17595 ad802fe986df2f4886edfbdd9854d649 399 SUPERFAMILY SSF53383 2 398 1.46E-88 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS17595 ad802fe986df2f4886edfbdd9854d649 399 Pfam PF00155 Aminotransferase class I and II 42 378 1.3E-43 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS17595 ad802fe986df2f4886edfbdd9854d649 399 Gene3D G3DSA:3.40.640.10 45 276 3.3E-64 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS07085 a5223c5418c8e0e541eb4014cbd8d476 513 SUPERFAMILY SSF56563 265 483 5.62E-6 T 09-03-2017 ARZXY2_RS09340 a3fe951491882ed579d47063a1809354 160 Gene3D G3DSA:2.30.110.10 4 159 5.3E-50 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09340 a3fe951491882ed579d47063a1809354 160 SUPERFAMILY SSF50475 6 132 2.24E-33 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09340 a3fe951491882ed579d47063a1809354 160 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 149 1.8E-45 T 09-03-2017 ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 Gene3D G3DSA:3.30.70.1350 220 296 2.1E-5 T 09-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 SUPERFAMILY SSF161111 16 213 2.75E-52 T 09-03-2017 ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 Gene3D G3DSA:1.20.1510.10 18 212 2.5E-57 T 09-03-2017 IPR027469 Cation efflux protein transmembrane domain ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 Pfam PF01545 Cation efflux family 21 212 4.0E-48 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 296 4.3E-83 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 ARZXY2_RS16725 da9a0f50c66fae68668888b82d899f72 306 SUPERFAMILY SSF160240 217 295 4.19E-11 T 09-03-2017 ARZXY2_RS08200 992abe0d54247a1d8fc2c61083307b6a 328 Pfam PF04198 Putative sugar-binding domain 58 314 5.2E-59 T 09-03-2017 IPR007324 Sugar-binding domain, putative GO:0030246 ARZXY2_RS08200 992abe0d54247a1d8fc2c61083307b6a 328 Gene3D G3DSA:1.10.10.10 14 46 7.9E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08200 992abe0d54247a1d8fc2c61083307b6a 328 SUPERFAMILY SSF100950 62 314 8.37E-62 T 09-03-2017 ARZXY2_RS08200 992abe0d54247a1d8fc2c61083307b6a 328 Gene3D G3DSA:3.40.50.1360 54 313 5.4E-76 T 09-03-2017 ARZXY2_RS08200 992abe0d54247a1d8fc2c61083307b6a 328 SUPERFAMILY SSF46689 11 70 6.27E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS09585 178defe81d374ee221003719786a41a7 114 Pfam PF01042 Endoribonuclease L-PSP 3 111 1.6E-21 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family ARZXY2_RS09585 178defe81d374ee221003719786a41a7 114 SUPERFAMILY SSF55298 2 112 5.81E-28 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS09585 178defe81d374ee221003719786a41a7 114 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 88 106 - T 09-03-2017 IPR019897 RidA, conserved site ARZXY2_RS09585 178defe81d374ee221003719786a41a7 114 Gene3D G3DSA:3.30.1330.40 3 112 8.2E-27 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS02575 0d8653e36ebd1fc0ed9c03e870a44381 351 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 107 253 5.5E-40 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS02575 0d8653e36ebd1fc0ed9c03e870a44381 351 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 107 252 1.0E-44 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 22 309 6.7E-74 T 09-03-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 ProSitePatterns PS01057 SAICAR synthetase signature 1. 116 130 - T 09-03-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 Gene3D G3DSA:3.30.470.20 128 260 1.5E-53 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 SUPERFAMILY SSF56104 15 311 7.85E-95 T 09-03-2017 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 20 308 24.081 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 Pfam PF01259 SAICAR synthetase 22 280 1.4E-99 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 ARZXY2_RS01680 cb341aa7c595fc0e6f64c681fe9bb538 312 Gene3D G3DSA:3.30.200.20 14 127 1.0E-39 T 09-03-2017 ARZXY2_RS01950 577390cb4582c485f997447e1c84d33e 443 Pfam PF01070 FMN-dependent dehydrogenase 78 439 8.3E-130 T 09-03-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 ARZXY2_RS01950 577390cb4582c485f997447e1c84d33e 443 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 333 339 - T 09-03-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 ARZXY2_RS01950 577390cb4582c485f997447e1c84d33e 443 Gene3D G3DSA:3.20.20.70 70 440 9.1E-130 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS01950 577390cb4582c485f997447e1c84d33e 443 PIRSF PIRSF000138 51 442 6.1E-130 T 09-03-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS01950 577390cb4582c485f997447e1c84d33e 443 SUPERFAMILY SSF51395 70 438 9.77E-98 T 09-03-2017 ARZXY2_RS04515 ba9ea69a9f271c35dfc0a37dc1d3d732 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 232 8.5E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04515 ba9ea69a9f271c35dfc0a37dc1d3d732 254 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 123 1.6E-19 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS04515 ba9ea69a9f271c35dfc0a37dc1d3d732 254 SUPERFAMILY SSF161098 24 217 4.32E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04515 ba9ea69a9f271c35dfc0a37dc1d3d732 254 Gene3D G3DSA:1.10.3720.10 24 232 8.8E-45 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11390 32a0a6074e7440e29b4d4fb3f2126af5 73 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 1.2E-26 T 09-03-2017 IPR021408 Protein of unknown function DUF3046 ARZXY2_RS12100 2e3c4b8057f3456c62b82f3e15e09ebe 113 Pfam PF14216 Domain of unknown function (DUF4326) 9 105 5.6E-24 T 09-03-2017 IPR025475 Protein of unknown function DUF4326) ARZXY2_RS05075 ed1ae7c148b5cadefe3fa70ac5dc4b17 267 Gene3D G3DSA:3.40.50.300 2 225 1.2E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05075 ed1ae7c148b5cadefe3fa70ac5dc4b17 267 Pfam PF00005 ABC transporter 17 161 5.0E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05075 ed1ae7c148b5cadefe3fa70ac5dc4b17 267 SUPERFAMILY SSF52540 4 222 2.83E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05075 ed1ae7c148b5cadefe3fa70ac5dc4b17 267 SMART SM00382 25 211 5.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05075 ed1ae7c148b5cadefe3fa70ac5dc4b17 267 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS15340 0fad6eff93ea241937126edc48c5b848 232 SUPERFAMILY SSF55961 3 116 1.47E-10 T 09-03-2017 ARZXY2_RS10210 b6839a3450a9f80be9e7dfcde3567f8d 190 Pfam PF01613 Flavin reductase like domain 32 182 9.0E-24 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS10210 b6839a3450a9f80be9e7dfcde3567f8d 190 SUPERFAMILY SSF50475 23 182 2.52E-31 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10210 b6839a3450a9f80be9e7dfcde3567f8d 190 Gene3D G3DSA:2.30.110.10 19 180 3.1E-39 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS10210 b6839a3450a9f80be9e7dfcde3567f8d 190 SMART SM00903 31 181 4.1E-29 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS00260 8f59a270ab0ad39e062f4d32c8678d76 360 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 42 302 2.8E-37 T 09-03-2017 IPR017039 Virulence factor BrkB ARZXY2_RS00260 8f59a270ab0ad39e062f4d32c8678d76 360 Pfam PF03631 Virulence factor BrkB 50 306 2.8E-65 T 09-03-2017 IPR017039 Virulence factor BrkB ARZXY2_RS00260 8f59a270ab0ad39e062f4d32c8678d76 360 PIRSF PIRSF035875 25 328 3.6E-84 T 09-03-2017 IPR017039 Virulence factor BrkB ARZXY2_RS11940 8a1d741a450cd5009b1e68edd51dd398 504 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 52 392 8.0E-43 T 09-03-2017 IPR006427 Phage portal protein, HK97 ARZXY2_RS11940 8a1d741a450cd5009b1e68edd51dd398 504 Pfam PF04860 Phage portal protein 55 386 2.1E-61 T 09-03-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 Gene3D G3DSA:3.40.50.1820 30 273 3.5E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 Pfam PF00561 alpha/beta hydrolase fold 37 259 8.0E-22 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 SUPERFAMILY SSF53474 29 272 1.5E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 8.2E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 8.2E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 8.2E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 8.2E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00412 Epoxide hydrolase signature 62 77 5.9E-5 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS09570 004010f86ceeaa134152e0842d8f3890 275 PRINTS PR00412 Epoxide hydrolase signature 248 270 5.9E-5 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 Gene3D G3DSA:1.10.10.10 35 160 2.6E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 SUPERFAMILY SSF46785 38 161 1.75E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 3.4E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 3.4E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 3.4E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 3.4E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 SMART SM00347 43 146 8.4E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS17150 8515b5cb4e3939f67109d4157ce91e8d 164 Pfam PF01047 MarR family 70 110 3.8E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS03720 a60787bbe87037d45cb13fddafb1ae7f 58 Pfam PF04964 Flp/Fap pilin component 17 56 8.8E-8 T 09-03-2017 IPR007047 Flp/Fap pilin component ARZXY2_RS19230 ae273e94e71d56be267f230696b48c8a 214 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 13 208 1.2E-56 T 09-03-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 ARZXY2_RS19230 ae273e94e71d56be267f230696b48c8a 214 SMART SM01120 36 211 3.0E-57 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS19230 ae273e94e71d56be267f230696b48c8a 214 SUPERFAMILY SSF101473 7 210 4.58E-49 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS19230 ae273e94e71d56be267f230696b48c8a 214 Pfam PF02734 DAK2 domain 38 210 3.4E-48 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 PRINTS PR00421 Thioredoxin family signature 29 38 2.9E-8 T 09-03-2017 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 PRINTS PR00421 Thioredoxin family signature 68 79 2.9E-8 T 09-03-2017 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 PRINTS PR00421 Thioredoxin family signature 21 29 2.9E-8 T 09-03-2017 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 Gene3D G3DSA:3.40.30.10 4 102 8.5E-30 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 Pfam PF00085 Thioredoxin 5 101 1.6E-24 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 ARZXY2_RS03065 166352ae88d1c77872f39bd598873c0a 126 SUPERFAMILY SSF52833 4 103 2.4E-29 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS04715 19521fa490e48d344128d49da23b7d28 341 SUPERFAMILY SSF51726 72 332 1.02E-18 T 09-03-2017 ARZXY2_RS04715 19521fa490e48d344128d49da23b7d28 341 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 332 9.4E-7 T 09-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 ARZXY2_RS04715 19521fa490e48d344128d49da23b7d28 341 Gene3D G3DSA:3.20.20.210 98 333 2.2E-8 T 09-03-2017 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 PIRSF PIRSF005900 1 151 2.0E-41 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 SUPERFAMILY SSF47240 1 145 4.06E-48 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 09-03-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 Pfam PF00210 Ferritin-like domain 9 145 6.9E-22 T 09-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 5.5E-10 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 5.5E-10 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 5.5E-10 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 ARZXY2_RS17260 77f587afede86d92456446f5fa5088fb 159 Gene3D G3DSA:1.20.1260.10 2 146 1.3E-45 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS02850 af99fc770f60d84fc9d163aa91c9a7a7 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 45 212 6.5E-37 T 09-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 ARZXY2_RS02850 af99fc770f60d84fc9d163aa91c9a7a7 237 SUPERFAMILY SSF52402 29 201 6.07E-38 T 09-03-2017 ARZXY2_RS02850 af99fc770f60d84fc9d163aa91c9a7a7 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 31 236 3.3E-56 T 09-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 ARZXY2_RS02850 af99fc770f60d84fc9d163aa91c9a7a7 237 PIRSF PIRSF000857 4 237 2.1E-82 T 09-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 ARZXY2_RS02850 af99fc770f60d84fc9d163aa91c9a7a7 237 Gene3D G3DSA:3.40.50.620 28 208 1.3E-47 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS10930 b1a52ea061c34c295dfd0e9a207626bc 467 Pfam PF01474 Class-II DAHP synthetase family 31 461 2.8E-192 T 09-03-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 ARZXY2_RS10930 b1a52ea061c34c295dfd0e9a207626bc 467 SUPERFAMILY SSF51569 26 464 8.79E-189 T 09-03-2017 ARZXY2_RS10930 b1a52ea061c34c295dfd0e9a207626bc 467 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 30 464 2.9E-203 T 09-03-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 SUPERFAMILY SSF48498 80 165 5.19E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.3E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.3E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 55 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 Gene3D G3DSA:1.10.357.10 12 170 1.3E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 SUPERFAMILY SSF46689 12 81 1.35E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20205 1330d545c1c96293376a9684078a416f 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 3.9E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS04020 6d9ff7b2da0bb34b42e76f51d4c43347 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 8.5E-20 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ARZXY2_RS04020 6d9ff7b2da0bb34b42e76f51d4c43347 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 17.553 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ARZXY2_RS04020 6d9ff7b2da0bb34b42e76f51d4c43347 123 TIGRFAM TIGR00494 crcB: protein CrcB 6 119 1.4E-26 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ARZXY2_RS18335 2f8f153b79f7b60f4df4c226de33bb31 228 Pfam PF03746 LamB/YcsF family 2 217 8.3E-90 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF ARZXY2_RS18335 2f8f153b79f7b60f4df4c226de33bb31 228 SUPERFAMILY SSF88713 2 227 1.04E-85 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS11555 711c4a6260d802f0cda00d0898241d55 113 SUPERFAMILY SSF64376 10 82 1.05E-20 T 09-03-2017 IPR007393 Domain of unknown function DUF448 ARZXY2_RS11555 711c4a6260d802f0cda00d0898241d55 113 Gene3D G3DSA:3.30.1230.10 10 83 7.7E-23 T 09-03-2017 IPR007393 Domain of unknown function DUF448 ARZXY2_RS11555 711c4a6260d802f0cda00d0898241d55 113 Pfam PF04296 Protein of unknown function (DUF448) 13 79 9.2E-22 T 09-03-2017 IPR007393 Domain of unknown function DUF448 ARZXY2_RS19905 a418d73ffbb7c9fb0ce1a89c869513b0 234 Pfam PF12697 Alpha/beta hydrolase family 3 222 2.3E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS19905 a418d73ffbb7c9fb0ce1a89c869513b0 234 SUPERFAMILY SSF53474 3 231 3.41E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19905 a418d73ffbb7c9fb0ce1a89c869513b0 234 Gene3D G3DSA:3.40.50.1820 3 232 4.2E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02595 75e2a070c7be9cec14aabfefe56378b2 576 Gene3D G3DSA:3.40.50.2000 356 552 4.7E-21 T 09-03-2017 ARZXY2_RS02595 75e2a070c7be9cec14aabfefe56378b2 576 Pfam PF13579 Glycosyl transferase 4-like domain 191 366 4.7E-14 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS02595 75e2a070c7be9cec14aabfefe56378b2 576 SUPERFAMILY SSF53756 177 574 2.71E-64 T 09-03-2017 ARZXY2_RS02595 75e2a070c7be9cec14aabfefe56378b2 576 Pfam PF00534 Glycosyl transferases group 1 383 552 3.3E-28 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 Gene3D G3DSA:3.30.70.920 59 136 1.4E-19 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 SUPERFAMILY SSF54909 66 146 4.02E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 Gene3D G3DSA:1.10.10.10 3 51 7.7E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 SUPERFAMILY SSF46785 3 63 9.1E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 Pfam PF01037 Lrp/AsnC ligand binding domain 73 139 9.6E-17 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 2.2E-11 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 SMART SM00344 4 110 8.1E-25 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.0E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.0E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS20415 abe80a145fe7fd858f14a32d675db64b 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.0E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS15750 fd1b8d42912edd12752716c009d5d31a 306 SUPERFAMILY SSF56784 20 252 2.55E-7 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS15750 fd1b8d42912edd12752716c009d5d31a 306 Gene3D G3DSA:3.40.50.1000 203 249 2.0E-5 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS15750 fd1b8d42912edd12752716c009d5d31a 306 Gene3D G3DSA:3.40.50.1000 21 96 2.0E-5 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 Gene3D G3DSA:1.10.150.170 129 233 6.7E-38 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 Gene3D G3DSA:3.40.50.150 234 327 1.3E-41 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 Gene3D G3DSA:3.40.50.150 14 126 1.3E-41 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 PIRSF PIRSF004486 8 327 1.8E-99 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 SUPERFAMILY SSF53335 14 129 3.76E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 SUPERFAMILY SSF53335 231 326 3.76E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 14 326 36.537 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 12 325 1.7E-94 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 SUPERFAMILY SSF81799 130 231 1.44E-34 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS10885 20e0046afdc973d943e1bf91c15c73b9 332 Pfam PF01795 MraW methylase family 13 326 1.7E-111 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 SUPERFAMILY SSF52540 1007 1091 9.56E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 SUPERFAMILY SSF52540 23 207 9.56E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 Gene3D G3DSA:3.40.1140.10 16 238 4.3E-17 T 09-03-2017 ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 Pfam PF13558 Putative exonuclease SbcCD, C subunit 988 1082 3.6E-16 T 09-03-2017 ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 Pfam PF13555 P-loop containing region of AAA domain 20 77 1.2E-18 T 09-03-2017 ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 SUPERFAMILY SSF52540 221 337 4.04E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 SUPERFAMILY SSF52540 970 1066 4.04E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20560 66a7f612184c7c20c95568fd092c9e3f 1147 SUPERFAMILY SSF52540 36 70 4.04E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12915 26b14c65c96b39b0dea17e59cb3baf1d 190 Pfam PF04138 GtrA-like protein 22 144 8.8E-25 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ARZXY2_RS00590 815a0c1725a8b220c2bc1f897f946e5d 213 Pfam PF01810 LysE type translocator 15 208 2.3E-27 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS00590 815a0c1725a8b220c2bc1f897f946e5d 213 PIRSF PIRSF006324 1 211 8.9E-42 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 Pfam PF00293 NUDIX domain 9 116 4.7E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 SUPERFAMILY SSF55811 5 139 2.3E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 Gene3D G3DSA:3.90.79.10 6 140 1.3E-31 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.6E-8 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS11275 6e1a215ab8e6fe45ba878e9f726828de 144 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.6E-8 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 185 2.6E-45 T 09-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 Gene3D G3DSA:3.40.50.1010 6 184 6.8E-45 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 SMART SM00475 7 280 6.8E-78 T 09-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 187 277 6.7E-20 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 SUPERFAMILY SSF47807 187 301 4.78E-20 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 SMART SM00279 189 224 1.8E-10 T 09-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 SUPERFAMILY SSF88723 6 165 1.05E-37 T 09-03-2017 IPR029060 PIN domain-like ARZXY2_RS09310 e1f5d0f9e09e6021de2617be907ea639 316 Gene3D G3DSA:1.10.150.20 185 254 6.6E-20 T 09-03-2017 ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 SUPERFAMILY SSF51735 3 213 1.27E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 211 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.0E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 Gene3D G3DSA:3.40.50.720 8 212 3.9E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 7.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 7.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 7.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS18085 96fabd5096cc5b99b6e445afa9a41249 231 Pfam PF00106 short chain dehydrogenase 9 186 2.9E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 Gene3D G3DSA:3.40.1410.10 78 243 1.3E-41 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 Gene3D G3DSA:1.10.10.10 9 77 3.5E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 3.4E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 SMART SM00345 21 80 2.2E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.2E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.2E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 SMART SM00866 100 238 7.9E-32 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 Pfam PF07702 UTRA domain 101 237 2.8E-33 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 SUPERFAMILY SSF46785 10 84 1.32E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS14050 1194f704a200f59bcb1d9d34ce2f3f2e 246 SUPERFAMILY SSF64288 68 243 4.24E-43 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain ARZXY2_RS01520 27b2bccd546c6d5be028ef92229ce46f 408 Gene3D G3DSA:1.20.1250.20 221 393 3.1E-14 T 09-03-2017 ARZXY2_RS01520 27b2bccd546c6d5be028ef92229ce46f 408 Gene3D G3DSA:1.20.1250.20 22 203 3.9E-28 T 09-03-2017 ARZXY2_RS01520 27b2bccd546c6d5be028ef92229ce46f 408 Pfam PF07690 Major Facilitator Superfamily 32 361 2.2E-33 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS01520 27b2bccd546c6d5be028ef92229ce46f 408 SUPERFAMILY SSF103473 14 396 3.79E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 Gene3D G3DSA:3.40.190.80 160 264 2.9E-22 T 09-03-2017 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 Pfam PF00459 Inositol monophosphatase family 22 257 6.4E-49 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 SUPERFAMILY SSF56655 8 264 9.82E-76 T 09-03-2017 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 5.2E-21 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 5.2E-21 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 5.2E-21 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 5.2E-21 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 5.2E-21 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 Gene3D G3DSA:3.30.540.10 7 159 2.8E-46 T 09-03-2017 ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site ARZXY2_RS05010 b192dc18395ac116fa19db91ef45538c 270 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 12 263 2.0E-91 T 09-03-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 ARZXY2_RS08030 931b98ec3a376dfea818e47e1b1fd488 271 Gene3D G3DSA:3.40.630.30 142 257 9.4E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS08030 931b98ec3a376dfea818e47e1b1fd488 271 Pfam PF00583 Acetyltransferase (GNAT) family 178 251 4.1E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS08030 931b98ec3a376dfea818e47e1b1fd488 271 SUPERFAMILY SSF55729 116 257 1.27E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PIRSF PIRSF006336 1 593 2.0E-210 T 09-03-2017 IPR026283 Beta-galactosidase 1-like GO:0004565 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 Gene3D G3DSA:2.60.120.260 458 574 6.3E-20 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 Gene3D G3DSA:3.20.20.80 7 329 1.7E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 Pfam PF01301 Glycosyl hydrolases family 35 13 325 1.9E-104 T 09-03-2017 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 150 162 - T 09-03-2017 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 SUPERFAMILY SSF51445 6 329 2.06E-95 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 93 112 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 148 163 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 37 55 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 297 313 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 234 249 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 16 33 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 528 544 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 PRINTS PR00742 Glycosyl hydrolase family 35 signature 270 285 6.6E-50 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 ARZXY2_RS04080 e1a20035cb7dbab148e07052beac399b 598 SUPERFAMILY SSF49785 455 574 4.5E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 Gene3D G3DSA:3.60.20.10 310 377 5.3E-52 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 Gene3D G3DSA:3.60.20.10 110 228 5.3E-52 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 SUPERFAMILY SSF56235 2 377 4.63E-89 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 Gene3D G3DSA:2.30.120.10 229 297 2.2E-9 T 09-03-2017 ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 Pfam PF01804 Penicillin amidase 2 386 8.8E-105 T 09-03-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 ARZXY2_RS22465 08f40ec1a3b276bbf50b3389f682f152 394 Gene3D G3DSA:1.10.439.10 2 109 3.0E-26 T 09-03-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 141 209 2.6E-5 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 125 7.1E-27 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 2 230 41.691 T 09-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 SUPERFAMILY SSF53254 1 222 8.57E-71 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 Gene3D G3DSA:3.40.50.1240 1 247 6.1E-89 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 4 247 1.3E-110 T 09-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 ARZXY2_RS14925 1cf3e8aa8c44a8de5b860ec457640ece 248 SMART SM00855 4 189 5.5E-23 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS18110 c06a7aba2981d18a433eccc8163612a6 361 Gene3D G3DSA:3.40.50.2000 3 161 4.6E-10 T 09-03-2017 ARZXY2_RS18110 c06a7aba2981d18a433eccc8163612a6 361 SUPERFAMILY SSF53756 3 347 7.85E-63 T 09-03-2017 ARZXY2_RS18110 c06a7aba2981d18a433eccc8163612a6 361 Gene3D G3DSA:3.40.50.2000 180 347 7.3E-53 T 09-03-2017 ARZXY2_RS18110 c06a7aba2981d18a433eccc8163612a6 361 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 176 323 2.6E-25 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 ARZXY2_RS15620 981191e6873eb5ae458b879de1b79594 441 SUPERFAMILY SSF53850 22 437 3.75E-72 T 09-03-2017 ARZXY2_RS15620 981191e6873eb5ae458b879de1b79594 441 Pfam PF01547 Bacterial extracellular solute-binding protein 47 351 1.3E-41 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS15620 981191e6873eb5ae458b879de1b79594 441 Gene3D G3DSA:3.40.190.10 172 370 2.1E-45 T 09-03-2017 ARZXY2_RS15620 981191e6873eb5ae458b879de1b79594 441 Gene3D G3DSA:3.40.190.10 36 171 3.0E-24 T 09-03-2017 ARZXY2_RS12975 4f038274c952d3f336d2f0a09d43dcbf 214 Pfam PF13302 Acetyltransferase (GNAT) domain 19 167 2.9E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS12975 4f038274c952d3f336d2f0a09d43dcbf 214 SUPERFAMILY SSF55729 11 175 8.92E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12975 4f038274c952d3f336d2f0a09d43dcbf 214 Gene3D G3DSA:3.40.630.30 10 176 1.5E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 Pfam PF01979 Amidohydrolase family 54 409 5.4E-45 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 Gene3D G3DSA:3.20.20.140 66 398 4.9E-75 T 09-03-2017 ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 SUPERFAMILY SSF51556 57 380 1.45E-70 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 Gene3D G3DSA:2.30.40.10 2 65 9.2E-18 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 SUPERFAMILY SSF51338 3 57 1.13E-19 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS19415 8ef1799ef27a60d4e3c62b31e781e442 456 SUPERFAMILY SSF51338 381 451 1.13E-19 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS18345 bfd804491e52cd559b3c8c61a975478e 239 SUPERFAMILY SSF53850 25 187 6.4E-20 T 09-03-2017 ARZXY2_RS18345 bfd804491e52cd559b3c8c61a975478e 239 Pfam PF03466 LysR substrate binding domain 26 110 2.0E-14 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS18345 bfd804491e52cd559b3c8c61a975478e 239 Pfam PF03466 LysR substrate binding domain 114 183 1.6E-6 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS18345 bfd804491e52cd559b3c8c61a975478e 239 Gene3D G3DSA:3.40.190.10 27 110 1.2E-12 T 09-03-2017 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Gene3D G3DSA:3.40.47.10 198 279 9.0E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Gene3D G3DSA:3.40.47.10 13 137 9.0E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 398 4.8E-124 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 PIRSF PIRSF000429 8 401 4.3E-120 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Pfam PF00108 Thiolase, N-terminal domain 14 267 1.1E-53 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 SUPERFAMILY SSF53901 11 271 2.88E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Pfam PF02803 Thiolase, C-terminal domain 276 398 5.3E-37 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 SUPERFAMILY SSF53901 278 398 5.13E-38 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Gene3D G3DSA:3.40.47.10 157 197 3.4E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS10480 f4ce0a403b8029a3c07539259ceadcaa 421 Gene3D G3DSA:3.40.47.10 281 399 3.4E-47 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS18100 b766b5d8e774049a201a560bb3eb94fa 422 Pfam PF13439 Glycosyltransferase Family 4 21 200 9.9E-32 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS18100 b766b5d8e774049a201a560bb3eb94fa 422 Gene3D G3DSA:3.40.50.2000 210 380 2.0E-39 T 09-03-2017 ARZXY2_RS18100 b766b5d8e774049a201a560bb3eb94fa 422 SUPERFAMILY SSF53756 1 402 3.14E-95 T 09-03-2017 ARZXY2_RS18100 b766b5d8e774049a201a560bb3eb94fa 422 Pfam PF00534 Glycosyl transferases group 1 213 378 5.6E-44 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS14730 8b677e7b8a96a4f2d4301c2f0500a781 106 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 5.0E-17 T 09-03-2017 IPR021401 Protein of unknown function DUF3040 ARZXY2_RS16175 a405a86f7192318e57ebacb8dfcd61eb 246 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 136 146 - T 09-03-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 ARZXY2_RS16175 a405a86f7192318e57ebacb8dfcd61eb 246 Pfam PF13350 Tyrosine phosphatase family 11 244 2.6E-31 T 09-03-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type ARZXY2_RS16175 a405a86f7192318e57ebacb8dfcd61eb 246 SUPERFAMILY SSF52799 5 244 3.13E-32 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like ARZXY2_RS16175 a405a86f7192318e57ebacb8dfcd61eb 246 Gene3D G3DSA:3.90.190.10 3 174 1.1E-14 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 SUPERFAMILY SSF82171 32 424 2.35E-36 T 09-03-2017 ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 Pfam PF00326 Prolyl oligopeptidase family 484 691 1.4E-42 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 Gene3D G3DSA:3.40.50.1820 443 691 1.0E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 SUPERFAMILY SSF53474 438 690 6.03E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 Gene3D G3DSA:2.130.10.10 17 126 3.1E-33 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS17840 b162a3e923794c32d47dff2b9c81844c 705 Gene3D G3DSA:2.130.10.10 226 442 3.1E-33 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS00265 b8e6d6f821c5803de4b7b1a6ce59bd69 279 SUPERFAMILY SSF51658 1 263 1.96E-54 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00265 b8e6d6f821c5803de4b7b1a6ce59bd69 279 Gene3D G3DSA:3.20.20.150 11 273 1.3E-54 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00265 b8e6d6f821c5803de4b7b1a6ce59bd69 279 Pfam PF01261 Xylose isomerase-like TIM barrel 36 220 1.4E-20 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS10940 272aa56f038f908599cf94b6dfbd9ba4 262 Gene3D G3DSA:3.40.50.1820 12 252 2.0E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10940 272aa56f038f908599cf94b6dfbd9ba4 262 PIRSF PIRSF017388 11 254 2.3E-59 T 09-03-2017 IPR012354 Esterase/lipase GO:0052689 ARZXY2_RS10940 272aa56f038f908599cf94b6dfbd9ba4 262 SUPERFAMILY SSF53474 16 253 5.63E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS10940 272aa56f038f908599cf94b6dfbd9ba4 262 Pfam PF12146 Serine aminopeptidase, S33 25 230 1.7E-14 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 138 150 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 318 330 4.4E-52 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 459 49.541 T 09-03-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 236 1.7E-80 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 332 6.7E-9 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 Pfam PF03129 Anticodon binding domain 367 456 1.6E-22 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 Gene3D G3DSA:3.40.50.800 363 457 5.4E-40 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 Gene3D G3DSA:3.30.930.10 8 362 3.8E-144 T 09-03-2017 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 SUPERFAMILY SSF55681 7 370 2.16E-119 T 09-03-2017 ARZXY2_RS12200 907fc351139413645bddb61ed85e2283 461 SUPERFAMILY SSF52954 354 458 2.42E-33 T 09-03-2017 IPR004154 Anticodon-binding ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 291 3.8E-83 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 3.7E-31 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 3.7E-31 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 3.7E-31 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 3.7E-31 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 09-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 296 53.752 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 SMART SM01130 10 298 2.8E-109 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 Gene3D G3DSA:3.20.20.70 12 299 3.0E-98 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 Pfam PF00701 Dihydrodipicolinate synthetase family 12 291 3.8E-80 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 SUPERFAMILY SSF51569 12 298 1.15E-85 T 09-03-2017 ARZXY2_RS11425 9e491ea3c755926c125aed1f2fd58bde 303 PIRSF PIRSF001365 9 302 7.3E-80 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 Gene3D G3DSA:3.90.79.10 8 146 4.8E-40 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 SUPERFAMILY SSF46785 156 223 3.54E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 Pfam PF00293 NUDIX domain 12 132 5.6E-15 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 Gene3D G3DSA:1.10.10.10 149 223 2.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS01380 15cecb40ef23c4c6da5a15979c2557af 244 SUPERFAMILY SSF55811 11 153 1.9E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 Gene3D G3DSA:3.40.190.10 53 136 6.8E-30 T 09-03-2017 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 Gene3D G3DSA:3.40.190.10 240 272 6.8E-30 T 09-03-2017 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 Gene3D G3DSA:3.40.190.10 137 239 5.5E-23 T 09-03-2017 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 79 92 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 SMART SM00062 56 279 6.9E-64 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 SUPERFAMILY SSF53850 8 272 1.67E-56 T 09-03-2017 ARZXY2_RS04305 348e7314644638211c6c77d9d481a86e 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 270 7.1E-52 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS16850 892c595c0a6dd573d1273d062dff3c5d 260 Pfam PF03591 AzlC protein 23 157 3.7E-31 T 09-03-2017 IPR011606 Branched-chain amino acid transport, permease ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 Gene3D G3DSA:3.40.390.10 274 395 8.0E-111 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 Gene3D G3DSA:3.40.390.10 435 650 8.0E-111 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 Pfam PF01431 Peptidase family M13 444 647 1.9E-73 T 09-03-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 436 448 1.1E-22 T 09-03-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 475 491 1.1E-22 T 09-03-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 548 559 1.1E-22 T 09-03-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 454 466 1.1E-22 T 09-03-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 SUPERFAMILY SSF55486 5 650 9.23E-209 T 09-03-2017 ARZXY2_RS08325 d2bb41fb7dc3c3ebd88ec6c8ea08681d 650 Pfam PF05649 Peptidase family M13 17 392 1.6E-96 T 09-03-2017 IPR008753 Peptidase M13, N-terminal domain GO:0006508 ARZXY2_RS19175 723205fb4b7f234b0325109327a1f1a1 389 SUPERFAMILY SSF56601 38 340 5.95E-64 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS19175 723205fb4b7f234b0325109327a1f1a1 389 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 09-03-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 ARZXY2_RS19175 723205fb4b7f234b0325109327a1f1a1 389 Gene3D G3DSA:3.40.710.10 38 336 4.9E-64 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS19175 723205fb4b7f234b0325109327a1f1a1 389 Pfam PF00144 Beta-lactamase 45 306 5.7E-46 T 09-03-2017 IPR001466 Beta-lactamase-related ARZXY2_RS18375 f4e0c132fa693e30af114b6fd79218a4 888 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 466 499 1.1E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS18375 f4e0c132fa693e30af114b6fd79218a4 888 Pfam PF01345 Domain of unknown function DUF11 453 501 1.1E-6 T 09-03-2017 IPR001434 Domain of unknown function DUF11 ARZXY2_RS18375 f4e0c132fa693e30af114b6fd79218a4 888 Pfam PF05738 Cna protein B-type domain 768 814 1.2E-8 T 09-03-2017 IPR008454 Collagen-binding surface protein Cna-like, B-type domain ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 Pfam PF00155 Aminotransferase class I and II 123 451 2.4E-17 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 Gene3D G3DSA:1.10.10.10 8 74 5.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 6.6E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 Gene3D G3DSA:3.40.640.10 132 348 3.2E-49 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 SUPERFAMILY SSF53383 97 467 3.99E-74 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 Gene3D G3DSA:3.90.1150.10 349 463 4.3E-5 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 SMART SM00345 9 66 1.4E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS17345 bbabf5dc11b5ae1eed401c97d7181d03 469 SUPERFAMILY SSF46785 7 70 1.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02795 f760a72ab570cecb8b9a2395b9b28650 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 257 1.1E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02795 f760a72ab570cecb8b9a2395b9b28650 263 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 54 149 4.0E-18 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS02795 f760a72ab570cecb8b9a2395b9b28650 263 SUPERFAMILY SSF161098 52 247 3.79E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02795 f760a72ab570cecb8b9a2395b9b28650 263 Gene3D G3DSA:1.10.3720.10 54 258 2.6E-40 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 SUPERFAMILY SSF53474 233 385 2.51E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 SUPERFAMILY SSF53474 67 109 2.51E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 SUPERFAMILY SSF53474 142 182 2.51E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 Pfam PF05448 Acetyl xylan esterase (AXE1) 234 280 5.9E-5 T 09-03-2017 IPR008391 Acetyl xylan esterase ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 Gene3D G3DSA:3.40.50.1820 150 184 3.5E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 Gene3D G3DSA:3.40.50.1820 56 118 3.5E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02000 bb296f96acb22ba4d0d18709e1430986 403 Gene3D G3DSA:3.40.50.1820 233 381 3.5E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08405 ad29250114e4882e3639922514ef6e3d 557 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 123 296 1.2E-59 T 09-03-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 ARZXY2_RS08405 ad29250114e4882e3639922514ef6e3d 557 SUPERFAMILY SSF81342 22 302 4.71E-65 T 09-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 ARZXY2_RS08405 ad29250114e4882e3639922514ef6e3d 557 Gene3D G3DSA:1.20.810.10 22 450 4.9E-88 T 09-03-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 ARZXY2_RS12680 1ab897ae146150a29e765a929314b6b3 261 SUPERFAMILY SSF102588 147 250 3.66E-20 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS12680 1ab897ae146150a29e765a929314b6b3 261 SUPERFAMILY SSF102588 7 96 3.66E-20 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS12680 1ab897ae146150a29e765a929314b6b3 261 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 187 1.0E-12 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 ARZXY2_RS12680 1ab897ae146150a29e765a929314b6b3 261 Gene3D G3DSA:3.40.50.10320 8 96 1.4E-12 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS12680 1ab897ae146150a29e765a929314b6b3 261 Gene3D G3DSA:3.40.50.10320 147 188 1.4E-12 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 ARZXY2_RS00510 31888562e8e26bb5045c2bcd836994dc 477 Gene3D G3DSA:1.20.1250.20 16 193 4.2E-26 T 09-03-2017 ARZXY2_RS00510 31888562e8e26bb5045c2bcd836994dc 477 Gene3D G3DSA:1.20.1250.20 263 471 5.6E-14 T 09-03-2017 ARZXY2_RS00510 31888562e8e26bb5045c2bcd836994dc 477 Pfam PF07690 Major Facilitator Superfamily 23 297 6.8E-25 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00510 31888562e8e26bb5045c2bcd836994dc 477 SUPERFAMILY SSF103473 15 203 1.1E-45 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS00510 31888562e8e26bb5045c2bcd836994dc 477 SUPERFAMILY SSF103473 254 468 1.1E-45 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS13445 b174bc0121d2f01664b58a48296b18c0 141 SUPERFAMILY SSF49764 4 132 3.0E-31 T 09-03-2017 IPR008978 HSP20-like chaperone ARZXY2_RS13445 b174bc0121d2f01664b58a48296b18c0 141 Gene3D G3DSA:2.60.40.790 6 130 2.2E-30 T 09-03-2017 IPR008978 HSP20-like chaperone ARZXY2_RS13445 b174bc0121d2f01664b58a48296b18c0 141 Pfam PF00011 Hsp20/alpha crystallin family 31 130 4.7E-22 T 09-03-2017 IPR002068 Alpha crystallin/Hsp20 domain ARZXY2_RS02385 1b3fce426a3d233026ac8f87dcb2924f 331 Gene3D G3DSA:1.20.1260.10 38 291 1.1E-97 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS02385 1b3fce426a3d233026ac8f87dcb2924f 331 SUPERFAMILY SSF47240 48 289 1.68E-77 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS02385 1b3fce426a3d233026ac8f87dcb2924f 331 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 28 316 5.1E-148 T 09-03-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 ARZXY2_RS02385 1b3fce426a3d233026ac8f87dcb2924f 331 Pfam PF05138 Phenylacetic acid catabolic protein 38 312 1.6E-97 T 09-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 ARZXY2_RS18190 926f4dd392b1519ce4733a18f3c0db65 208 Pfam PF13828 Domain of unknown function (DUF4190) 131 191 1.8E-15 T 09-03-2017 IPR025241 Domain of unknown function DUF4190 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 16 420 2.8E-142 T 09-03-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 SUPERFAMILY SSF46977 469 547 7.85E-16 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Gene3D G3DSA:3.90.700.10 245 360 4.3E-33 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 4.6E-11 T 09-03-2017 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 4.6E-11 T 09-03-2017 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 549 1.2E-6 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 SUPERFAMILY SSF51905 17 270 1.42E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 SUPERFAMILY SSF51905 368 424 1.42E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Pfam PF00890 FAD binding domain 17 404 2.0E-90 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Gene3D G3DSA:3.50.50.60 361 422 1.7E-93 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Gene3D G3DSA:3.50.50.60 17 244 1.7E-93 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 SUPERFAMILY SSF56425 239 365 5.98E-34 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS05520 5b7ad4800335f628e61c1a5547e996a5 573 Gene3D G3DSA:1.20.58.100 469 549 1.9E-14 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS16300 bd39fd67ed8e5722ffdfb3fe1064fab2 415 Pfam PF00872 Transposase, Mutator family 29 382 1.3E-112 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS17925 bd39fd67ed8e5722ffdfb3fe1064fab2 415 Pfam PF00872 Transposase, Mutator family 29 382 1.3E-112 T 09-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 315 2.5E-20 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 SUPERFAMILY SSF52283 22 136 1.83E-24 T 09-03-2017 ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 Gene3D G3DSA:3.40.50.720 30 112 3.1E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 Gene3D G3DSA:3.40.50.720 113 284 2.9E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 SUPERFAMILY SSF51735 107 284 2.63E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09770 4d3de0d2c5d6165a0873edda5f4f8ba8 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 283 6.6E-53 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS01435 700448791fe764f907e11b9b9f9c2a93 190 Gene3D G3DSA:2.40.33.20 24 164 5.0E-15 T 09-03-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like ARZXY2_RS01435 700448791fe764f907e11b9b9f9c2a93 190 SUPERFAMILY SSF50800 10 165 1.26E-22 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 SUPERFAMILY SSF74731 3 117 7.85E-43 T 09-03-2017 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 Gene3D G3DSA:1.10.1900.20 56 117 1.6E-29 T 09-03-2017 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 9.5E-41 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 Pfam PF00453 Ribosomal protein L20 3 109 6.1E-41 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.4E-35 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.4E-35 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.4E-35 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.487 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS11290 74091a0390e0cc807d9d87a0fe7dde21 226 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 2.0E-13 T 09-03-2017 ARZXY2_RS13370 030f99c013056908b62cdb1cf30375bf 356 Gene3D G3DSA:3.30.360.10 176 354 1.8E-43 T 09-03-2017 ARZXY2_RS13370 030f99c013056908b62cdb1cf30375bf 356 SUPERFAMILY SSF51735 19 183 1.63E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13370 030f99c013056908b62cdb1cf30375bf 356 Gene3D G3DSA:3.40.50.720 21 175 7.8E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13370 030f99c013056908b62cdb1cf30375bf 356 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 26 147 2.6E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS13370 030f99c013056908b62cdb1cf30375bf 356 SUPERFAMILY SSF55347 156 319 1.32E-32 T 09-03-2017 ARZXY2_RS01025 24f1ddb6e2e2acf30e317c292efb0ec2 104 SUPERFAMILY SSF103481 5 101 4.45E-11 T 09-03-2017 ARZXY2_RS01025 24f1ddb6e2e2acf30e317c292efb0ec2 104 Pfam PF00893 Small Multidrug Resistance protein 1 89 9.2E-19 T 09-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 ARZXY2_RS07860 05f53ca94afd6b10a2b9e46fa93f7e69 267 SUPERFAMILY SSF54637 129 253 6.93E-11 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS07860 05f53ca94afd6b10a2b9e46fa93f7e69 267 Pfam PF13622 Thioesterase-like superfamily 31 261 2.2E-32 T 09-03-2017 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 Pfam PF00155 Aminotransferase class I and II 47 388 2.3E-68 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 09-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 Gene3D G3DSA:3.90.1150.10 281 391 1.1E-30 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 397 52.707 T 09-03-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 392 2.8E-184 T 09-03-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 Gene3D G3DSA:3.40.640.10 62 280 2.5E-92 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS12295 7458123acc290d867fcf422982663992 399 SUPERFAMILY SSF53383 5 391 8.11E-115 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS06035 2e2e4b20b34d5ab41c8586b9e7b4ae20 192 Gene3D G3DSA:3.40.50.150 38 145 2.2E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS06035 2e2e4b20b34d5ab41c8586b9e7b4ae20 192 Pfam PF08241 Methyltransferase domain 40 134 2.6E-24 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 ARZXY2_RS06035 2e2e4b20b34d5ab41c8586b9e7b4ae20 192 SUPERFAMILY SSF53335 21 174 2.66E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS11675 88296a719414d8b7f5145e57b3b64a82 282 Gene3D G3DSA:3.20.20.60 12 236 1.5E-66 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS11675 88296a719414d8b7f5145e57b3b64a82 282 SUPERFAMILY SSF51621 10 236 2.37E-61 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS11675 88296a719414d8b7f5145e57b3b64a82 282 PIRSF PIRSF015582 2 282 2.3E-72 T 09-03-2017 IPR011206 Citrate lyase beta subunit-like ARZXY2_RS11675 88296a719414d8b7f5145e57b3b64a82 282 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 224 4.5E-31 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 Pfam PF01047 MarR family 35 93 4.9E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 Gene3D G3DSA:1.10.10.10 2 142 8.7E-43 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 SMART SM00347 28 126 3.3E-22 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.3E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.3E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.3E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS13190 653f914809b174f01027f95b7d948ce8 144 SUPERFAMILY SSF46785 5 141 5.27E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02985 f3a520776ff948444a1050dc8963d670 211 Pfam PF09365 Conserved hypothetical protein (DUF2461) 11 204 1.5E-50 T 09-03-2017 IPR012808 Conserved hypothetical protein CHP02453 ARZXY2_RS02985 f3a520776ff948444a1050dc8963d670 211 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 10 205 1.7E-41 T 09-03-2017 IPR012808 Conserved hypothetical protein CHP02453 ARZXY2_RS02985 f3a520776ff948444a1050dc8963d670 211 PIRSF PIRSF028451 3 209 3.8E-36 T 09-03-2017 IPR015996 Uncharacterised conserved protein UCP028451 ARZXY2_RS07040 62d5ee50f9aded2c156bed6151cff3f9 256 SUPERFAMILY SSF53098 40 251 3.19E-51 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07040 62d5ee50f9aded2c156bed6151cff3f9 256 Gene3D G3DSA:3.30.420.10 50 212 3.9E-38 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS07040 62d5ee50f9aded2c156bed6151cff3f9 256 Pfam PF01351 Ribonuclease HII 52 249 2.1E-30 T 09-03-2017 IPR024567 Ribonuclease HII/HIII domain ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 1179 8.8E-70 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 SUPERFAMILY SSF52540 988 1179 1.62E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 SUPERFAMILY SSF52540 1 202 1.62E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 PIRSF PIRSF005719 1 1190 2.8E-249 T 09-03-2017 IPR024704 Structural maintenance of chromosomes protein ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 Gene3D G3DSA:3.40.50.300 1035 1182 6.4E-86 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 Gene3D G3DSA:3.40.50.300 1 158 6.4E-86 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 Pfam PF06470 SMC proteins Flexible Hinge Domain 505 617 3.6E-18 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1188 22.156 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 SMART SM00968 505 618 1.6E-16 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 SUPERFAMILY SSF75553 461 643 5.23E-21 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 ARZXY2_RS06945 909c5d634fa6587500666e23ad45ef9a 1190 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 1 1186 2.7E-270 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 ARZXY2_RS19165 a7f66fdbf7884be98464bade8665fcad 465 SUPERFAMILY SSF53474 70 393 2.57E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19165 a7f66fdbf7884be98464bade8665fcad 465 Gene3D G3DSA:3.40.50.1820 71 434 2.7E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS19165 a7f66fdbf7884be98464bade8665fcad 465 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 171 186 - T 09-03-2017 IPR019826 Carboxylesterase type B, active site ARZXY2_RS19165 a7f66fdbf7884be98464bade8665fcad 465 Pfam PF00135 Carboxylesterase family 73 220 5.9E-36 T 09-03-2017 IPR002018 Carboxylesterase, type B ARZXY2_RS18620 78a425f7e2faf8b4f2bc9036694ff3ff 531 Gene3D G3DSA:2.60.120.260 404 508 5.7E-4 T 09-03-2017 IPR008979 Galactose-binding domain-like ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 Gene3D G3DSA:1.10.8.60 225 292 3.0E-5 T 09-03-2017 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 SUPERFAMILY SSF52540 55 297 4.42E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 SMART SM00382 75 224 2.2E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 SMART SM00382 377 549 5.5E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 Gene3D G3DSA:3.40.50.300 342 563 4.3E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 SUPERFAMILY SSF52540 340 613 5.04E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 381 399 2.4E-16 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 454 472 2.4E-16 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 487 501 2.4E-16 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 424 442 2.4E-16 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 Gene3D G3DSA:3.40.50.300 55 222 1.4E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 Pfam PF07724 AAA domain (Cdc48 subfamily) 380 540 1.9E-22 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS06580 df1ecf6fa36ddfdd5e026e79bf45beea 620 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 79 201 8.7E-13 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 ARZXY2_RS16970 8e63b0febc3dde8a3705c7e3eaf8721e 273 SUPERFAMILY SSF56529 54 271 8.5E-71 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS16970 8e63b0febc3dde8a3705c7e3eaf8721e 273 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 66 269 8.8E-62 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS16970 8e63b0febc3dde8a3705c7e3eaf8721e 273 Gene3D G3DSA:3.90.850.10 59 271 3.4E-74 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS01040 07f3bc2772d9b433ef70b3d565ff464e 150 SUPERFAMILY SSF55961 3 150 9.17E-32 T 09-03-2017 ARZXY2_RS01040 07f3bc2772d9b433ef70b3d565ff464e 150 Gene3D G3DSA:3.30.530.20 3 150 1.9E-31 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS01040 07f3bc2772d9b433ef70b3d565ff464e 150 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 149 4.8E-21 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 ARZXY2_RS10255 c3ffd1292e3951791a027a0d649b91aa 392 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 27 277 2.6E-40 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ARZXY2_RS10255 c3ffd1292e3951791a027a0d649b91aa 392 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 30 281 3.3E-61 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ARZXY2_RS10255 c3ffd1292e3951791a027a0d649b91aa 392 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 21 287 14.794 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ARZXY2_RS10255 c3ffd1292e3951791a027a0d649b91aa 392 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 157 169 - T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 ARZXY2_RS01390 a8c8eca2a7cae630ca1b1dafc1c66f06 409 Pfam PF01566 Natural resistance-associated macrophage protein 25 377 1.4E-57 T 09-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 214 1.8E-91 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 206 7.7E-38 T 09-03-2017 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 ProSitePatterns PS00548 Ribosomal protein S3 signature. 167 201 - T 09-03-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 SUPERFAMILY SSF54821 111 210 3.92E-38 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 Pfam PF07650 KH domain 42 114 2.3E-18 T 09-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 SMART SM00322 64 129 4.9E-6 T 09-03-2017 IPR004087 K Homology domain GO:0003676 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 Gene3D G3DSA:3.30.1140.32 112 211 1.1E-43 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 210 37.827 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 SUPERFAMILY SSF54814 2 110 7.06E-33 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 ARZXY2_RS03525 c48ebfc999d24103ab62b4b6914756c6 273 Gene3D G3DSA:3.30.300.20 17 111 2.6E-30 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS15725 e612bb27649f8bba462d2c485a94c2ad 444 Gene3D G3DSA:3.40.190.10 334 376 1.5E-17 T 09-03-2017 ARZXY2_RS15725 e612bb27649f8bba462d2c485a94c2ad 444 Gene3D G3DSA:3.40.190.10 48 163 1.5E-17 T 09-03-2017 ARZXY2_RS15725 e612bb27649f8bba462d2c485a94c2ad 444 SUPERFAMILY SSF53850 34 439 1.09E-45 T 09-03-2017 ARZXY2_RS15725 e612bb27649f8bba462d2c485a94c2ad 444 Pfam PF13416 Bacterial extracellular solute-binding protein 65 346 1.8E-16 T 09-03-2017 ARZXY2_RS15725 e612bb27649f8bba462d2c485a94c2ad 444 Gene3D G3DSA:3.40.190.10 165 333 9.2E-23 T 09-03-2017 ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 Gene3D G3DSA:3.40.50.720 2 259 6.0E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.8E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.8E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 200 0.0049 T 09-03-2017 ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.0E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 SUPERFAMILY SSF51735 1 258 2.5E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS15425 7d05d993c35b5674a0b1ddb24bc20f44 263 Pfam PF00106 short chain dehydrogenase 7 210 8.8E-48 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17085 cda062a0f2b4c4269c6ca7fc77953bd7 329 SUPERFAMILY SSF53213 2 189 8.11E-72 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS17085 cda062a0f2b4c4269c6ca7fc77953bd7 329 SUPERFAMILY SSF53213 230 304 8.11E-72 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS17085 cda062a0f2b4c4269c6ca7fc77953bd7 329 Gene3D G3DSA:3.40.830.10 232 305 1.6E-81 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS17085 cda062a0f2b4c4269c6ca7fc77953bd7 329 Gene3D G3DSA:3.40.830.10 1 191 1.6E-81 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS17085 cda062a0f2b4c4269c6ca7fc77953bd7 329 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 300 3.6E-46 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 ARZXY2_RS06460 d5730f5a3fc2684b482dbf3eea3409f2 113 Gene3D G3DSA:3.40.30.10 18 97 4.7E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS06460 d5730f5a3fc2684b482dbf3eea3409f2 113 SUPERFAMILY SSF52833 17 93 1.0E-8 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS06460 d5730f5a3fc2684b482dbf3eea3409f2 113 Pfam PF00462 Glutaredoxin 19 76 3.3E-6 T 09-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 ARZXY2_RS09575 016cd0e1c0367b397744211460a4ef96 336 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 255 2.3E-17 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS09575 016cd0e1c0367b397744211460a4ef96 336 Gene3D G3DSA:3.10.180.10 144 284 5.7E-39 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09575 016cd0e1c0367b397744211460a4ef96 336 Gene3D G3DSA:3.10.180.10 11 127 1.1E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09575 016cd0e1c0367b397744211460a4ef96 336 SUPERFAMILY SSF54593 2 258 1.02E-38 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS06695 5613ddd38a86ce317a66eb660e653570 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 131 3.4E-14 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06695 5613ddd38a86ce317a66eb660e653570 138 SUPERFAMILY SSF52788 5 135 7.2E-26 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS06695 5613ddd38a86ce317a66eb660e653570 138 Gene3D G3DSA:3.40.50.270 6 131 5.2E-25 T 09-03-2017 ARZXY2_RS06695 5613ddd38a86ce317a66eb660e653570 138 SMART SM00226 6 134 1.3E-18 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 33 369 42.454 T 09-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 32 367 2.8E-114 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 36 367 1.1E-104 T 09-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 49 58 - T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 SUPERFAMILY SSF51726 35 368 6.1E-94 T 09-03-2017 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 Gene3D G3DSA:3.20.20.210 29 368 1.8E-133 T 09-03-2017 ARZXY2_RS04460 2204856bbb8a13240f725782fe6e1961 371 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 166 182 - T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 ARZXY2_RS20300 7287a37edfed347a5b75d70d7a032fbf 375 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 279 339 1.4E-8 T 09-03-2017 ARZXY2_RS20300 7287a37edfed347a5b75d70d7a032fbf 375 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 179 239 6.9E-10 T 09-03-2017 ARZXY2_RS20300 7287a37edfed347a5b75d70d7a032fbf 375 SUPERFAMILY SSF69318 143 370 5.75E-33 T 09-03-2017 ARZXY2_RS20300 7287a37edfed347a5b75d70d7a032fbf 375 Gene3D G3DSA:2.130.10.130 84 353 2.8E-20 T 09-03-2017 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 Gene3D G3DSA:3.40.190.10 313 361 2.7E-7 T 09-03-2017 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 Gene3D G3DSA:3.40.190.10 10 104 2.7E-7 T 09-03-2017 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 Pfam PF12849 PBP superfamily domain 39 340 5.4E-50 T 09-03-2017 IPR024370 PBP domain ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 Gene3D G3DSA:3.40.190.10 132 309 5.2E-50 T 09-03-2017 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 SUPERFAMILY SSF53850 49 370 1.61E-82 T 09-03-2017 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 PIRSF PIRSF002756 7 372 5.6E-109 T 09-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 ARZXY2_RS17660 5f37b93ca38e325ea815d884bc3c88b1 373 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 50 369 1.7E-68 T 09-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 ARZXY2_RS03640 2c0c99b71571cae655f5bb8e0004ff29 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 274 3.6E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03640 2c0c99b71571cae655f5bb8e0004ff29 278 SUPERFAMILY SSF161098 40 266 1.44E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03640 2c0c99b71571cae655f5bb8e0004ff29 278 Gene3D G3DSA:1.10.3720.10 47 274 1.0E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13860 b4ad9b36bd38fda50d2d2f69ce59df46 77 Gene3D G3DSA:3.30.40.10 8 59 3.2E-4 T 09-03-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type ARZXY2_RS13860 b4ad9b36bd38fda50d2d2f69ce59df46 77 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 44 76 8.0E-10 T 09-03-2017 ARZXY2_RS12340 cc86e3d9033975c756caa8094e76a569 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 269 1.2E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS12340 cc86e3d9033975c756caa8094e76a569 344 Gene3D G3DSA:1.10.3720.10 102 331 9.6E-47 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS12340 cc86e3d9033975c756caa8094e76a569 344 SUPERFAMILY SSF161098 96 322 6.28E-50 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS18120 356f43dfdb1531741da5a065503dd205 316 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 152 272 4.4E-23 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 ARZXY2_RS18120 356f43dfdb1531741da5a065503dd205 316 SUPERFAMILY SSF53756 13 314 5.65E-53 T 09-03-2017 ARZXY2_RS18120 356f43dfdb1531741da5a065503dd205 316 Gene3D G3DSA:3.40.50.2000 13 63 7.0E-8 T 09-03-2017 ARZXY2_RS18120 356f43dfdb1531741da5a065503dd205 316 Gene3D G3DSA:3.40.50.2000 145 314 4.4E-37 T 09-03-2017 ARZXY2_RS16705 6ea48fb42a4a03fc67fb6b71fe834054 310 SUPERFAMILY SSF103481 213 308 1.57E-13 T 09-03-2017 ARZXY2_RS16705 6ea48fb42a4a03fc67fb6b71fe834054 310 SUPERFAMILY SSF103481 71 169 4.97E-14 T 09-03-2017 ARZXY2_RS16705 6ea48fb42a4a03fc67fb6b71fe834054 310 Pfam PF00892 EamA-like transporter family 177 309 5.3E-19 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS16705 6ea48fb42a4a03fc67fb6b71fe834054 310 Pfam PF00892 EamA-like transporter family 33 164 1.8E-15 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS17655 341396e2c933faffc8e1c2337a65b9a0 310 SUPERFAMILY SSF161098 30 299 2.45E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17655 341396e2c933faffc8e1c2337a65b9a0 310 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 17 303 7.4E-79 T 09-03-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 ARZXY2_RS17655 341396e2c933faffc8e1c2337a65b9a0 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 299 7.2E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17655 341396e2c933faffc8e1c2337a65b9a0 310 Gene3D G3DSA:1.10.3720.10 30 304 3.5E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS17070 ec723c3ace0de98f5dd58165cee5b053 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 92 256 1.5E-5 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17070 ec723c3ace0de98f5dd58165cee5b053 261 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 260 6.8E-111 T 09-03-2017 IPR012690 2-oxo-hepta-3-ene-1,7-dioic acid hydratase GO:0019439 ARZXY2_RS17070 ec723c3ace0de98f5dd58165cee5b053 261 SUPERFAMILY SSF56529 2 260 1.83E-75 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17070 ec723c3ace0de98f5dd58165cee5b053 261 Gene3D G3DSA:3.90.850.10 1 260 2.0E-81 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS13205 1072d4be094701d3ded90d618acb77e7 111 PIRSF PIRSF000178 1 104 6.8E-9 T 09-03-2017 ARZXY2_RS13205 1072d4be094701d3ded90d618acb77e7 111 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 1 99 7.1E-27 T 09-03-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13205 1072d4be094701d3ded90d618acb77e7 111 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 96 2.1E-19 T 09-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 ARZXY2_RS13205 1072d4be094701d3ded90d618acb77e7 111 SUPERFAMILY SSF81343 1 102 9.37E-25 T 09-03-2017 ARZXY2_RS13205 1072d4be094701d3ded90d618acb77e7 111 Gene3D G3DSA:1.20.1300.10 1 101 2.4E-26 T 09-03-2017 ARZXY2_RS08595 68f50ea3ccf0e95e1ac76dd9d5d389d3 247 Pfam PF00535 Glycosyl transferase family 2 6 168 2.6E-30 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS08595 68f50ea3ccf0e95e1ac76dd9d5d389d3 247 SUPERFAMILY SSF53448 6 216 4.5E-42 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08595 68f50ea3ccf0e95e1ac76dd9d5d389d3 247 Gene3D G3DSA:3.90.550.10 6 218 6.4E-24 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS15385 f22b377d427b143e3d78b444c7dbb9e9 425 SUPERFAMILY SSF53448 52 316 2.49E-64 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS15385 f22b377d427b143e3d78b444c7dbb9e9 425 Pfam PF13641 Glycosyltransferase like family 2 57 277 7.9E-34 T 09-03-2017 ARZXY2_RS15385 f22b377d427b143e3d78b444c7dbb9e9 425 Gene3D G3DSA:3.90.550.10 55 293 8.3E-53 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS17065 e164f29c9df25e5db9a574b960aa775f 245 SUPERFAMILY SSF51621 1 232 3.08E-75 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS17065 e164f29c9df25e5db9a574b960aa775f 245 Gene3D G3DSA:3.20.20.60 1 227 2.0E-71 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 ARZXY2_RS17065 e164f29c9df25e5db9a574b960aa775f 245 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 1 223 1.1E-50 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 ARZXY2_RS05480 9e23c655dffa1b1ea6dfacf4329ce0b9 275 Gene3D G3DSA:3.40.50.1820 205 272 4.5E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS05480 9e23c655dffa1b1ea6dfacf4329ce0b9 275 Gene3D G3DSA:3.40.50.1820 11 152 4.5E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS05480 9e23c655dffa1b1ea6dfacf4329ce0b9 275 SUPERFAMILY SSF53474 6 257 4.02E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS05480 9e23c655dffa1b1ea6dfacf4329ce0b9 275 Pfam PF00561 alpha/beta hydrolase fold 36 182 1.1E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS11670 e05f1efe6a34cdf4f0526735b68e70ae 373 Gene3D G3DSA:3.40.50.720 7 149 8.1E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11670 e05f1efe6a34cdf4f0526735b68e70ae 373 SUPERFAMILY SSF51735 8 159 6.59E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11670 e05f1efe6a34cdf4f0526735b68e70ae 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 126 1.4E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS11670 e05f1efe6a34cdf4f0526735b68e70ae 373 Gene3D G3DSA:3.30.360.10 150 355 1.0E-27 T 09-03-2017 ARZXY2_RS11670 e05f1efe6a34cdf4f0526735b68e70ae 373 SUPERFAMILY SSF55347 137 298 5.07E-32 T 09-03-2017 ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 SUPERFAMILY SSF56784 28 257 5.6E-37 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 Pfam PF02358 Trehalose-phosphatase 31 220 4.6E-32 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 28 222 9.7E-14 T 09-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 28 257 2.3E-29 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 Gene3D G3DSA:3.40.50.1000 181 261 2.8E-38 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS14765 7f9190c46af2a118b05e9691a2863279 267 Gene3D G3DSA:3.40.50.1000 27 103 2.8E-38 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS18255 ddf66497e5007871b231d0a860876fa5 78 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 1 78 9.0E-17 T 09-03-2017 IPR020311 Uncharacterised protein family, Rv0898c ARZXY2_RS18255 ddf66497e5007871b231d0a860876fa5 78 Pfam PF10944 Protein of unknown function (DUF2630) 2 78 3.1E-32 T 09-03-2017 IPR020311 Uncharacterised protein family, Rv0898c ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 SUPERFAMILY SSF56281 5 458 7.99E-122 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 Pfam PF00753 Metallo-beta-lactamase superfamily 23 207 3.6E-11 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 SMART SM00849 19 220 2.5E-10 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 Pfam PF10996 Beta-Casp domain 255 372 1.6E-22 T 09-03-2017 IPR022712 Beta-Casp domain ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 SMART SM01027 253 372 3.6E-44 T 09-03-2017 IPR022712 Beta-Casp domain ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 386 449 6.2E-11 T 09-03-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 Gene3D G3DSA:3.60.15.10 9 106 3.0E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS09865 3c967ca3f853924494b812a052756501 461 Gene3D G3DSA:3.60.15.10 141 263 3.0E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS11110 b004729388078c9ad395371f79cb20cc 220 SUPERFAMILY SSF55811 23 196 6.09E-39 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS11110 b004729388078c9ad395371f79cb20cc 220 Pfam PF00293 NUDIX domain 59 177 3.2E-16 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS11110 b004729388078c9ad395371f79cb20cc 220 Gene3D G3DSA:3.90.79.10 23 198 2.0E-47 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS05515 26487df956ec51872876b2f56a74c454 435 Hamap MF_00569 Quinolinate synthase A [nadA]. 78 432 53.116 T 09-03-2017 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 ARZXY2_RS05515 26487df956ec51872876b2f56a74c454 435 Pfam PF02445 Quinolinate synthetase A protein 85 431 2.9E-107 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 ARZXY2_RS05515 26487df956ec51872876b2f56a74c454 435 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 80 431 2.1E-89 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 ARZXY2_RS05515 26487df956ec51872876b2f56a74c454 435 SUPERFAMILY SSF142754 88 431 9.02E-94 T 09-03-2017 ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 Gene3D G3DSA:3.40.50.720 1 145 6.7E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 SUPERFAMILY SSF55347 133 263 1.8E-26 T 09-03-2017 ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 SUPERFAMILY SSF51735 3 159 1.3E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 Gene3D G3DSA:3.30.360.10 146 338 3.9E-36 T 09-03-2017 ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 245 5.6E-13 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS13645 7d7d9adf8e59d42a52d6c49631428f95 368 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 6.7E-24 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS15250 531565c57f89951226525a99ed0e6c9e 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 126 7.1E-24 T 09-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 ARZXY2_RS15250 531565c57f89951226525a99ed0e6c9e 132 Gene3D G3DSA:3.30.479.10 1 126 1.6E-36 T 09-03-2017 ARZXY2_RS15250 531565c57f89951226525a99ed0e6c9e 132 SUPERFAMILY SSF55620 1 125 2.11E-26 T 09-03-2017 ARZXY2_RS10955 992a7aedbafc947b729a742a9fa5dd87 352 SUPERFAMILY SSF53067 35 344 1.59E-64 T 09-03-2017 ARZXY2_RS10955 992a7aedbafc947b729a742a9fa5dd87 352 Gene3D G3DSA:3.30.420.40 34 169 8.2E-46 T 09-03-2017 ARZXY2_RS10955 992a7aedbafc947b729a742a9fa5dd87 352 Gene3D G3DSA:3.30.420.40 170 318 1.7E-49 T 09-03-2017 ARZXY2_RS10955 992a7aedbafc947b729a742a9fa5dd87 352 Pfam PF00480 ROK family 38 344 5.3E-75 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS10955 992a7aedbafc947b729a742a9fa5dd87 352 ProSitePatterns PS01125 ROK family signature. 164 191 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS10815 17a15314f1cc296fb5a8b9237e934e30 177 Hamap MF_01197 Cell division protein SepF [sepF]. 2 167 20.86 T 09-03-2017 IPR023052 Cell division protein SepF GO:0090529 ARZXY2_RS10815 17a15314f1cc296fb5a8b9237e934e30 177 Pfam PF04472 Protein of unknown function (DUF552) 88 159 3.9E-24 T 09-03-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 ARZXY2_RS15830 34ee0e6ecc34745e32152722e0c95007 99 Pfam PF13834 Domain of unknown function (DUF4193) 2 98 2.6E-30 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 ProSitePatterns PS00433 Phosphofructokinase signature. 97 115 - T 09-03-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 Pfam PF00365 Phosphofructokinase 2 128 5.4E-31 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 SUPERFAMILY SSF53784 2 169 1.7E-42 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 Gene3D G3DSA:3.40.50.460 2 121 2.4E-26 T 09-03-2017 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 115 6.5E-21 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 25 6.5E-21 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS09960 76c193b91a140e834af6d48eb85ffb6e 173 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 43 55 6.5E-21 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 261 9.8E-94 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 271 365 1.9E-23 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 SUPERFAMILY SSF101790 292 372 2.45E-24 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 SUPERFAMILY SSF103025 5 286 1.19E-94 T 09-03-2017 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Gene3D G3DSA:3.30.1360.120 142 240 1.1E-56 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Gene3D G3DSA:3.30.1360.120 6 53 1.1E-56 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Gene3D G3DSA:3.30.70.1400 54 141 3.2E-28 T 09-03-2017 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 371 42.587 T 09-03-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 6 371 2.0E-108 T 09-03-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 Gene3D G3DSA:2.40.30.110 292 365 1.2E-28 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 ARZXY2_RS19590 62b94706c7f102c2df10cc8635bfba99 373 PIRSF PIRSF006487 1 373 2.8E-98 T 09-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 ARZXY2_RS14700 f66d11aa3282b0a499fde770a5520c85 243 Pfam PF01904 Protein of unknown function DUF72 20 237 1.7E-63 T 09-03-2017 IPR002763 Protein of unknown function DUF72 ARZXY2_RS14700 f66d11aa3282b0a499fde770a5520c85 243 SUPERFAMILY SSF117396 1 241 2.49E-80 T 09-03-2017 IPR002763 Protein of unknown function DUF72 ARZXY2_RS14700 f66d11aa3282b0a499fde770a5520c85 243 Gene3D G3DSA:3.20.20.410 1 241 9.5E-80 T 09-03-2017 IPR002763 Protein of unknown function DUF72 ARZXY2_RS03645 410674a12509e9e5cff5763266fdfbbc 315 Pfam PF03576 Peptidase family S58 8 305 9.4E-63 T 09-03-2017 IPR005321 Peptidase S58, DmpA ARZXY2_RS03645 410674a12509e9e5cff5763266fdfbbc 315 SUPERFAMILY SSF56266 4 303 1.23E-62 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS03645 410674a12509e9e5cff5763266fdfbbc 315 Gene3D G3DSA:3.60.70.12 2 306 1.7E-70 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 ARZXY2_RS19785 95c365b25c666997173c5376cddb2a72 174 Pfam PF04343 Protein of unknown function, DUF488 15 132 6.0E-31 T 09-03-2017 IPR007438 Protein of unknown function DUF488 ARZXY2_RS19785 95c365b25c666997173c5376cddb2a72 174 PIRSF PIRSF024492 1 173 5.2E-50 T 09-03-2017 IPR014519 Uncharacterised conserved protein UCP024492 ARZXY2_RS04230 dd41e06ab0c4c754f48181fc16e89c54 319 SUPERFAMILY SSF52266 96 300 1.3E-22 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS04230 dd41e06ab0c4c754f48181fc16e89c54 319 Gene3D G3DSA:3.40.50.1110 123 301 1.0E-18 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS04230 dd41e06ab0c4c754f48181fc16e89c54 319 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 130 290 3.0E-13 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS16595 fb6a03ea7330677819d6ecb3e5fa7d6f 134 SUPERFAMILY SSF47413 8 65 7.6E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16595 fb6a03ea7330677819d6ecb3e5fa7d6f 134 Gene3D G3DSA:1.10.260.40 6 65 2.4E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS16595 fb6a03ea7330677819d6ecb3e5fa7d6f 134 SMART SM00530 13 68 0.0067 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS16595 fb6a03ea7330677819d6ecb3e5fa7d6f 134 Pfam PF01381 Helix-turn-helix 14 62 6.2E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS00390 07eed09ccdbc1e42041813fa71c2fb11 86 Pfam PF14019 Protein of unknown function (DUF4235) 6 79 1.7E-22 T 09-03-2017 IPR025329 Protein of unknown function DUF4235 ARZXY2_RS03290 1457b57fb2b2f7e6397d3fa66f98fe62 130 SUPERFAMILY SSF46785 8 82 6.62E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS03290 1457b57fb2b2f7e6397d3fa66f98fe62 130 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 2.2E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS03290 1457b57fb2b2f7e6397d3fa66f98fe62 130 SMART SM00345 19 78 1.2E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS03290 1457b57fb2b2f7e6397d3fa66f98fe62 130 Gene3D G3DSA:1.10.10.10 5 78 4.6E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS08750 6b29b16d79fcc75f9a10352ad2a93141 387 Pfam PF13692 Glycosyl transferases group 1 217 333 1.7E-11 T 09-03-2017 ARZXY2_RS08750 6b29b16d79fcc75f9a10352ad2a93141 387 SUPERFAMILY SSF53756 65 369 7.85E-22 T 09-03-2017 ARZXY2_RS02870 55fea07f3265c17bce02505032601c93 383 Gene3D G3DSA:3.40.190.10 155 285 4.2E-17 T 09-03-2017 ARZXY2_RS02870 55fea07f3265c17bce02505032601c93 383 Pfam PF13379 NMT1-like family 67 305 3.6E-34 T 09-03-2017 ARZXY2_RS02870 55fea07f3265c17bce02505032601c93 383 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 72 364 4.5E-54 T 09-03-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 ARZXY2_RS02870 55fea07f3265c17bce02505032601c93 383 SUPERFAMILY SSF53850 71 296 2.54E-36 T 09-03-2017 ARZXY2_RS10415 546906585ca715b4c61b6ff2174788fd 75 Pfam PF14013 MT0933-like antitoxin protein 9 54 1.2E-15 T 09-03-2017 IPR028037 Antitoxin Rv0909/MT0933 ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 Gene3D G3DSA:3.40.50.360 22 150 1.1E-52 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 Hamap MF_00128 Protein NrdI [nrdI]. 21 151 32.388 T 09-03-2017 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 SUPERFAMILY SSF52218 19 150 1.91E-25 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 PIRSF PIRSF005087 19 155 2.3E-51 T 09-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 Pfam PF07972 NrdI Flavodoxin like 23 141 5.5E-46 T 09-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI ARZXY2_RS07795 f53187b1b6dfb7be9744aadf755c86ab 156 TIGRFAM TIGR00333 nrdI: nrdI protein 23 149 8.4E-45 T 09-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI ARZXY2_RS01340 331b463833c11ebbbb5f488d798c6662 236 SMART SM00382 29 208 1.2E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01340 331b463833c11ebbbb5f488d798c6662 236 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01340 331b463833c11ebbbb5f488d798c6662 236 Gene3D G3DSA:3.40.50.300 7 217 1.6E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01340 331b463833c11ebbbb5f488d798c6662 236 Pfam PF00005 ABC transporter 21 159 3.5E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01340 331b463833c11ebbbb5f488d798c6662 236 SUPERFAMILY SSF52540 6 217 3.9E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 Gene3D G3DSA:3.40.605.10 3 243 1.1E-88 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 SUPERFAMILY SSF53720 4 452 2.49E-151 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 Pfam PF00171 Aldehyde dehydrogenase family 5 449 7.6E-157 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 Gene3D G3DSA:3.40.309.10 244 429 1.1E-54 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS07155 42bca76fd7d4bcfbc05186f52e8ca9d1 457 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS13030 dd0b40818984d9c175c1ab044b7e5f9d 426 Pfam PF01594 Domain of unknown function DUF20 31 355 1.5E-63 T 09-03-2017 IPR002549 Transmembrane protein TqsA-like ARZXY2_RS15205 93869e40462d429b311baf06a0ac8f33 174 SUPERFAMILY SSF53254 7 156 7.5E-23 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS15205 93869e40462d429b311baf06a0ac8f33 174 Gene3D G3DSA:3.40.50.1240 4 173 7.2E-52 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS15205 93869e40462d429b311baf06a0ac8f33 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 84 4.1E-9 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 95 108 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 225 249 2.0E-26 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 73 89 2.0E-26 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 194 215 2.0E-26 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 95 111 2.0E-26 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 51 71 2.0E-26 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 SUPERFAMILY SSF56655 11 259 1.83E-57 T 09-03-2017 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 Gene3D G3DSA:3.30.540.10 11 151 8.0E-36 T 09-03-2017 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 Gene3D G3DSA:3.40.190.80 172 248 9.7E-23 T 09-03-2017 ARZXY2_RS12390 348c41cac0ade5f58611415ed292c7de 280 Pfam PF00459 Inositol monophosphatase family 12 250 8.2E-46 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 ARZXY2_RS14755 203c9744799eaff4f9f967c66b318c20 292 Pfam PF13462 Thioredoxin 129 288 2.5E-24 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS14755 203c9744799eaff4f9f967c66b318c20 292 Gene3D G3DSA:3.40.30.10 127 282 2.6E-29 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS14755 203c9744799eaff4f9f967c66b318c20 292 SUPERFAMILY SSF52833 126 280 8.98E-29 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS14335 4e88d888f49a5e8353e236e88c75bbcb 111 Pfam PF11662 Protein of unknown function (DUF3263) 31 102 7.6E-37 T 09-03-2017 IPR021678 Protein of unknown function DUF3263 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 Pfam PF00334 Nucleoside diphosphate kinase 4 138 2.6E-52 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 29.708 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 SMART SM00562 3 138 1.2E-66 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 SUPERFAMILY SSF54919 3 138 3.27E-52 T 09-03-2017 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 09-03-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 Gene3D G3DSA:3.30.70.141 3 138 2.4E-55 T 09-03-2017 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.2E-33 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.2E-33 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.2E-33 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS07650 a6c02072de40764e9c88bb63b68ec0ee 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 4.2E-33 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 ARZXY2_RS18915 8757a95da9b1808a41faa4937720e1f0 420 Gene3D G3DSA:2.130.10.10 59 415 9.0E-17 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 ARZXY2_RS18915 8757a95da9b1808a41faa4937720e1f0 420 SUPERFAMILY SSF50969 298 415 6.43E-16 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like ARZXY2_RS18915 8757a95da9b1808a41faa4937720e1f0 420 SUPERFAMILY SSF50969 57 268 6.43E-16 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like ARZXY2_RS16220 9763633d0ade6871dbe851ba4b7eb442 466 Gene3D G3DSA:1.10.2020.10 52 146 2.7E-22 T 09-03-2017 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 ARZXY2_RS16220 9763633d0ade6871dbe851ba4b7eb442 466 Gene3D G3DSA:3.20.20.140 147 466 1.8E-140 T 09-03-2017 ARZXY2_RS16220 9763633d0ade6871dbe851ba4b7eb442 466 Gene3D G3DSA:3.20.20.140 7 50 1.8E-140 T 09-03-2017 ARZXY2_RS16220 9763633d0ade6871dbe851ba4b7eb442 466 Pfam PF02614 Glucuronate isomerase 21 456 3.8E-78 T 09-03-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 ARZXY2_RS16220 9763633d0ade6871dbe851ba4b7eb442 466 SUPERFAMILY SSF51556 8 465 6.8E-141 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS03105 556b2b40ee9dc0806db58cbaacf05382 445 SUPERFAMILY SSF103473 14 440 2.09E-62 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03105 556b2b40ee9dc0806db58cbaacf05382 445 Pfam PF07690 Major Facilitator Superfamily 29 372 8.2E-32 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS03105 556b2b40ee9dc0806db58cbaacf05382 445 Gene3D G3DSA:1.20.1250.20 17 207 2.1E-24 T 09-03-2017 ARZXY2_RS03105 556b2b40ee9dc0806db58cbaacf05382 445 Gene3D G3DSA:1.20.1250.20 253 442 6.2E-21 T 09-03-2017 ARZXY2_RS01370 d6e8c9ab3f2e036c2c9bc1bb601feb41 300 SUPERFAMILY SSF111331 74 213 4.8E-14 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS01370 d6e8c9ab3f2e036c2c9bc1bb601feb41 300 Gene3D G3DSA:2.60.200.30 163 290 1.4E-10 T 09-03-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS01370 d6e8c9ab3f2e036c2c9bc1bb601feb41 300 Gene3D G3DSA:3.40.50.10330 60 162 2.1E-4 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 Gene3D G3DSA:3.40.192.10 9 145 5.4E-42 T 09-03-2017 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 Gene3D G3DSA:3.40.50.720 146 274 4.3E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 SUPERFAMILY SSF53223 5 123 5.08E-37 T 09-03-2017 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 122 3.5E-36 T 09-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 125 292 6.8E-56 T 09-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 Hamap MF_01576 Bifunctional protein FolD [folD]. 5 293 35.857 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 SUPERFAMILY SSF51735 124 292 1.04E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 76 103 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 111 132 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 211 240 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 160 180 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 266 284 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS13280 ad94e849d7fb4b995dea6ea5c88e982d 296 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 35 57 1.7E-64 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 24 245 2.6E-36 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 PIRSF PIRSF004848 13 249 6.6E-58 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 Gene3D G3DSA:3.20.20.10 12 246 2.7E-71 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 91 105 - T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 SUPERFAMILY SSF51419 18 243 3.66E-55 T 09-03-2017 IPR029066 PLP-binding barrel ARZXY2_RS10820 00101967dc82f6eba36a79b32d7cbea4 249 Pfam PF01168 Alanine racemase, N-terminal domain 25 246 8.2E-16 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 ARZXY2_RS18330 009c3fde0fb305c82d3c5adbc3b7f00b 445 SUPERFAMILY SSF103473 13 433 5.1E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS18330 009c3fde0fb305c82d3c5adbc3b7f00b 445 Pfam PF07690 Major Facilitator Superfamily 64 393 3.6E-26 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS18330 009c3fde0fb305c82d3c5adbc3b7f00b 445 Gene3D G3DSA:1.20.1250.20 249 437 6.0E-19 T 09-03-2017 ARZXY2_RS18330 009c3fde0fb305c82d3c5adbc3b7f00b 445 Gene3D G3DSA:1.20.1250.20 29 218 7.3E-19 T 09-03-2017 ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 Gene3D G3DSA:3.40.50.300 301 302 7.5E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 Gene3D G3DSA:3.40.50.300 171 251 7.5E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 Gene3D G3DSA:3.40.50.300 481 584 7.5E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 Gene3D G3DSA:3.40.50.300 585 736 9.0E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 Pfam PF13245 Part of AAA domain 191 249 9.1E-15 T 09-03-2017 ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 SUPERFAMILY SSF52540 334 363 8.4E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 SUPERFAMILY SSF52540 170 249 8.4E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11175 ee4226a08a67968887b041180b07e3a7 742 SUPERFAMILY SSF52540 484 735 8.4E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11750 f996147d9b499a4900f50318e5e5c055 535 Pfam PF00474 Sodium:solute symporter family 45 453 3.6E-94 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS11750 f996147d9b499a4900f50318e5e5c055 535 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 45 453 3.5E-59 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS04110 dad6ba2027f682c34eeebf5b77a564fc 406 Pfam PF00155 Aminotransferase class I and II 60 393 8.8E-49 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS04110 dad6ba2027f682c34eeebf5b77a564fc 406 SUPERFAMILY SSF53383 7 403 1.12E-94 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS04110 dad6ba2027f682c34eeebf5b77a564fc 406 Gene3D G3DSA:3.40.640.10 51 280 1.1E-67 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS04110 dad6ba2027f682c34eeebf5b77a564fc 406 Gene3D G3DSA:3.90.1150.10 281 403 2.3E-37 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS07290 2d17d04b9f68170e414c37a68788ee48 83 Pfam PF01610 Transposase 2 82 6.5E-5 T 09-03-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 SUPERFAMILY SSF88659 123 186 5.98E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 SUPERFAMILY SSF88946 17 120 1.07E-13 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 186 5.2E-15 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 Gene3D G3DSA:1.10.1740.10 16 123 3.5E-15 T 09-03-2017 ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 Gene3D G3DSA:1.10.10.10 130 187 1.7E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15400 0c4da1f06204276cd8e29277204206bc 545 Pfam PF04542 Sigma-70 region 2 36 103 5.8E-8 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Gene3D G3DSA:1.10.275.10 6 140 2.9E-55 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 471 78.517 T 09-03-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.2E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.2E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.2E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 1.2E-29 T 09-03-2017 IPR000362 Fumarate lyase family ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 7.3E-6 T 09-03-2017 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 7.3E-6 T 09-03-2017 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 7.3E-6 T 09-03-2017 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Pfam PF10415 Fumarase C C-terminus 410 469 1.4E-19 T 09-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Gene3D G3DSA:1.20.200.10 141 401 1.2E-93 T 09-03-2017 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Gene3D G3DSA:1.10.40.30 410 468 4.8E-19 T 09-03-2017 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 Pfam PF00206 Lyase 15 344 3.5E-100 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 SUPERFAMILY SSF48557 7 469 7.66E-145 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 ARZXY2_RS12960 494d0f10ee664d1138a31334a8462949 475 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 ARZXY2_RS13405 6804ef6c5165a2ec14ea06d7aeda3ce1 316 Gene3D G3DSA:3.40.50.10490 16 267 1.7E-79 T 09-03-2017 ARZXY2_RS13405 6804ef6c5165a2ec14ea06d7aeda3ce1 316 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 19 312 39.577 T 09-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 ARZXY2_RS13405 6804ef6c5165a2ec14ea06d7aeda3ce1 316 Pfam PF01380 SIS domain 138 224 9.1E-12 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS13405 6804ef6c5165a2ec14ea06d7aeda3ce1 316 SUPERFAMILY SSF53697 25 265 6.47E-63 T 09-03-2017 ARZXY2_RS13405 6804ef6c5165a2ec14ea06d7aeda3ce1 316 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 24 313 6.5E-108 T 09-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 ARZXY2_RS09595 1067bf28dd9e214a63d01927351c2a3e 373 Pfam PF13478 XdhC Rossmann domain 206 352 1.4E-39 T 09-03-2017 IPR027051 XdhC Rossmann domain ARZXY2_RS09595 1067bf28dd9e214a63d01927351c2a3e 373 Pfam PF02625 XdhC and CoxI family 13 77 8.7E-23 T 09-03-2017 IPR003777 XdhC- CoxI ARZXY2_RS03215 e7337e7c7998b73a3293ee92fd38cef4 307 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 276 7.6E-54 T 09-03-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 ARZXY2_RS03215 e7337e7c7998b73a3293ee92fd38cef4 307 Gene3D G3DSA:3.60.130.10 6 291 4.0E-84 T 09-03-2017 ARZXY2_RS03215 e7337e7c7998b73a3293ee92fd38cef4 307 SUPERFAMILY SSF51197 8 292 1.33E-78 T 09-03-2017 ARZXY2_RS17985 fae4f33663d6d7daec34802503709d99 301 SUPERFAMILY SSF51717 36 299 6.54E-89 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ARZXY2_RS17985 fae4f33663d6d7daec34802503709d99 301 Pfam PF00809 Pterin binding enzyme 40 284 2.9E-78 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ARZXY2_RS17985 fae4f33663d6d7daec34802503709d99 301 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 39 297 3.0E-86 T 09-03-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 ARZXY2_RS17985 fae4f33663d6d7daec34802503709d99 301 Gene3D G3DSA:3.20.20.20 34 301 6.9E-103 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ARZXY2_RS17985 fae4f33663d6d7daec34802503709d99 301 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 39 54 - T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 ARZXY2_RS03070 1dcccea8e259519c89ebdbdd86ea2aa9 92 Pfam PF03992 Antibiotic biosynthesis monooxygenase 11 77 1.2E-9 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain ARZXY2_RS03070 1dcccea8e259519c89ebdbdd86ea2aa9 92 SUPERFAMILY SSF54909 7 91 9.08E-14 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS03070 1dcccea8e259519c89ebdbdd86ea2aa9 92 Gene3D G3DSA:3.30.70.900 2 92 5.6E-17 T 09-03-2017 ARZXY2_RS02620 80d11bd1addd98a97da13a9ac48acf98 240 SUPERFAMILY SSF53474 9 125 5.69E-6 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS02620 80d11bd1addd98a97da13a9ac48acf98 240 Gene3D G3DSA:3.40.50.1820 37 190 4.7E-4 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS18645 280865500ca5877fef1e44a659744820 481 PIRSF PIRSF010361 1 453 4.8E-103 T 09-03-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane ARZXY2_RS18645 280865500ca5877fef1e44a659744820 481 Pfam PF09594 Protein of unknown function (DUF2029) 136 347 7.1E-14 T 09-03-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 Gene3D G3DSA:1.20.1560.10 13 323 1.1E-60 T 09-03-2017 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 Pfam PF00664 ABC transporter transmembrane region 25 296 9.2E-41 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 SMART SM00382 368 553 2.1E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 SUPERFAMILY SSF90123 13 323 6.02E-63 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 Pfam PF00005 ABC transporter 359 506 1.7E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 SUPERFAMILY SSF52540 333 573 8.59E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS01705 da234f04d561a9d5f8a7be48b05ac522 599 Gene3D G3DSA:3.40.50.300 342 571 8.9E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12355 fbff7317cd09898f5b871786845bf4ad 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 6.2E-22 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ARZXY2_RS12355 fbff7317cd09898f5b871786845bf4ad 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 1.9E-14 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ARZXY2_RS12355 fbff7317cd09898f5b871786845bf4ad 98 SUPERFAMILY SSF141000 4 94 3.92E-25 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ARZXY2_RS12355 fbff7317cd09898f5b871786845bf4ad 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 20.991 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 9.2E-6 T 09-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 PRINTS PR01005 Flagellar hook-associated protein signature 164 188 9.2E-6 T 09-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 414 466 2.0E-8 T 09-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 Pfam PF00460 Flagella basal body rod protein 7 37 1.4E-5 T 09-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 466 5.3E-80 T 09-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 ARZXY2_RS14595 c0a9280b46e7028a3088f7edc9390167 473 SUPERFAMILY SSF64518 170 466 1.57E-11 T 09-03-2017 ARZXY2_RS12360 e5c88c87dfc9d4dc6409cb318de74fe8 496 Pfam PF03600 Citrate transporter 248 441 7.4E-26 T 09-03-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 ARZXY2_RS12360 e5c88c87dfc9d4dc6409cb318de74fe8 496 Pfam PF03600 Citrate transporter 13 193 8.8E-32 T 09-03-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 ARZXY2_RS21090 ac4ba4a960ee107fff7e2047b20149e0 129 SUPERFAMILY SSF56235 6 120 3.6E-16 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS21090 ac4ba4a960ee107fff7e2047b20149e0 129 Pfam PF01804 Penicillin amidase 6 120 8.8E-20 T 09-03-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 ARZXY2_RS21090 ac4ba4a960ee107fff7e2047b20149e0 129 Gene3D G3DSA:3.60.20.10 6 120 1.4E-20 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS17800 4039852e9f40eef72937f67bb5130f95 58 SUPERFAMILY SSF69047 4 57 1.31E-7 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS17800 4039852e9f40eef72937f67bb5130f95 58 Gene3D G3DSA:1.10.1470.10 4 57 1.7E-12 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS17800 4039852e9f40eef72937f67bb5130f95 58 Pfam PF05532 CsbD-like 5 57 3.0E-16 T 09-03-2017 IPR008462 CsbD-like ARZXY2_RS12065 849c0bc85ba89d7bc4cbc306039cb573 80 Pfam PF11662 Protein of unknown function (DUF3263) 2 67 4.2E-18 T 09-03-2017 IPR021678 Protein of unknown function DUF3263 ARZXY2_RS00365 9d8c6a652c47b984d35dccd9288a8fe6 166 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 108 1.9E-26 T 09-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Pfam PF13188 PAS domain 211 250 4.8E-6 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 481 1.1E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 521 1.1E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Gene3D G3DSA:3.30.450.20 32 168 2.3E-36 T 09-03-2017 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 SUPERFAMILY SSF55890 332 401 1.02E-6 T 09-03-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Gene3D G3DSA:3.30.450.20 205 322 5.0E-8 T 09-03-2017 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 SUPERFAMILY SSF55785 204 286 4.82E-6 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 SMART SM00387 427 554 8.3E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 SUPERFAMILY SSF55874 400 553 4.06E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Pfam PF17203 Single cache domain 3 35 167 2.4E-21 T 09-03-2017 IPR033463 Single cache domain 3 ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 431 552 1.2E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 SUPERFAMILY SSF103190 36 166 2.83E-29 T 09-03-2017 IPR029151 Periplasmic sensor domain-like ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Gene3D G3DSA:3.30.565.10 398 558 3.1E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11065 4239f9518b08b132bbca03aba1588859 560 Gene3D G3DSA:1.10.287.130 323 372 8.3E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 SUPERFAMILY SSF55486 1 668 1.26E-158 T 09-03-2017 ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 Gene3D G3DSA:1.20.1050.40 11 139 2.1E-18 T 09-03-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 Pfam PF01432 Peptidase family M3 224 668 5.0E-115 T 09-03-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 Gene3D G3DSA:1.10.1370.10 140 341 1.8E-100 T 09-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 Gene3D G3DSA:1.10.1370.10 494 670 1.8E-100 T 09-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 ARZXY2_RS07940 44bde1755e7b87cece81a10bc1c26a29 672 Gene3D G3DSA:3.40.390.10 353 493 4.6E-47 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 ARZXY2_RS01375 a287ef803841fcb3000f52c298f7e41c 341 Pfam PF01145 SPFH domain / Band 7 family 21 195 1.6E-21 T 09-03-2017 IPR001107 Band 7 domain ARZXY2_RS01375 a287ef803841fcb3000f52c298f7e41c 341 SUPERFAMILY SSF117892 63 190 3.66E-9 T 09-03-2017 IPR001107 Band 7 domain ARZXY2_RS12460 26155825bd7b785793e8db24f9729475 390 Gene3D G3DSA:3.30.70.1230 226 375 4.0E-18 T 09-03-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 ARZXY2_RS12460 26155825bd7b785793e8db24f9729475 390 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 226 375 2.2E-11 T 09-03-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 ARZXY2_RS12460 26155825bd7b785793e8db24f9729475 390 SUPERFAMILY SSF55073 224 380 1.88E-30 T 09-03-2017 IPR029787 Nucleotide cyclase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Pfam PF00580 UvrD/REP helicase N-terminal domain 72 343 4.4E-77 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:3.40.50.300 253 357 1.5E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:3.40.50.300 67 172 1.5E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:1.10.10.160 176 252 1.4E-23 T 09-03-2017 IPR013986 DExx box DNA helicase domain ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:3.40.50.300 636 727 2.0E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:3.40.50.300 358 460 2.0E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 SUPERFAMILY SSF52540 68 726 1.11E-177 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Gene3D G3DSA:1.10.486.10 461 611 5.0E-51 T 09-03-2017 ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 68 838 2.6E-288 T 09-03-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 ARZXY2_RS14115 8aa49e160808db26d89d0da98dc91c45 843 Pfam PF13361 UvrD-like helicase C-terminal domain 349 699 1.4E-67 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 ARZXY2_RS10280 8343e3a4cd6c14b66e2a1a4a156a7d00 201 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 23 201 1.9E-39 T 09-03-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp ARZXY2_RS07225 e574f2d132857ed462c7590849bc7a3f 140 Gene3D G3DSA:3.30.450.20 10 134 3.7E-14 T 09-03-2017 ARZXY2_RS07225 e574f2d132857ed462c7590849bc7a3f 140 Pfam PF13426 PAS domain 22 134 6.5E-7 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS07225 e574f2d132857ed462c7590849bc7a3f 140 SUPERFAMILY SSF55785 10 133 1.27E-11 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS07225 e574f2d132857ed462c7590849bc7a3f 140 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 135 3.6E-6 T 09-03-2017 IPR000014 PAS domain ARZXY2_RS05325 d2f1d2058bf9ed272523e63ea170ff20 366 Gene3D G3DSA:3.20.20.70 3 357 1.4E-116 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS05325 d2f1d2058bf9ed272523e63ea170ff20 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 347 1.4E-66 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS05325 d2f1d2058bf9ed272523e63ea170ff20 366 SUPERFAMILY SSF51395 3 359 4.58E-106 T 09-03-2017 ARZXY2_RS02865 eec3e836ed2403818b0860f755f8f7b0 317 Pfam PF02574 Homocysteine S-methyltransferase 17 309 2.3E-74 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ARZXY2_RS02865 eec3e836ed2403818b0860f755f8f7b0 317 Gene3D G3DSA:3.20.20.330 4 316 8.3E-96 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ARZXY2_RS02865 eec3e836ed2403818b0860f755f8f7b0 317 SUPERFAMILY SSF82282 13 313 4.32E-86 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 ARZXY2_RS18810 280c189fbb3fa368599fe75a36ac836f 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 132 1.7E-14 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS18810 280c189fbb3fa368599fe75a36ac836f 299 SUPERFAMILY SSF111331 9 295 1.26E-31 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS18810 280c189fbb3fa368599fe75a36ac836f 299 SMART SM00046 9 141 0.0016 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS18810 280c189fbb3fa368599fe75a36ac836f 299 Gene3D G3DSA:3.40.50.200 54 113 3.6E-4 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 ARZXY2_RS12010 1be2db96736cc63a629e98ca0bf46143 250 Gene3D G3DSA:2.160.20.20 25 243 1.5E-6 T 09-03-2017 IPR012332 P22 tailspike C-terminal domain-like ARZXY2_RS09330 d274c29c249ae8f36a61616bd7669652 440 SUPERFAMILY SSF103473 24 415 1.05E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS09330 d274c29c249ae8f36a61616bd7669652 440 Gene3D G3DSA:1.20.1250.20 26 202 5.6E-16 T 09-03-2017 ARZXY2_RS09330 d274c29c249ae8f36a61616bd7669652 440 Gene3D G3DSA:1.20.1250.20 232 414 2.7E-17 T 09-03-2017 ARZXY2_RS09330 d274c29c249ae8f36a61616bd7669652 440 Pfam PF07690 Major Facilitator Superfamily 28 332 1.1E-13 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS07925 63bc799baef6bf8925c8fd84d4b7f4c7 192 Gene3D G3DSA:3.30.428.10 50 190 6.0E-40 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS07925 63bc799baef6bf8925c8fd84d4b7f4c7 192 SUPERFAMILY SSF54197 31 182 7.11E-42 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS07925 63bc799baef6bf8925c8fd84d4b7f4c7 192 Pfam PF01230 HIT domain 66 158 1.4E-15 T 09-03-2017 IPR001310 Histidine triad (HIT) protein ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 TIGRFAM TIGR00012 L29: ribosomal protein uL29 18 67 7.4E-19 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 Pfam PF00831 Ribosomal L29 protein 13 67 3.5E-23 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 8 67 15.699 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 SUPERFAMILY SSF46561 11 70 2.75E-20 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 Gene3D G3DSA:1.10.287.310 11 71 1.4E-27 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS03535 b53378b2527c03d14175e434314ce8fd 106 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 09-03-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 ARZXY2_RS02340 d2b10433835a3951d6148497b14fa7ee 353 Gene3D G3DSA:1.25.40.10 51 136 4.3E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS02340 d2b10433835a3951d6148497b14fa7ee 353 SUPERFAMILY SSF48452 249 322 9.49E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS02340 d2b10433835a3951d6148497b14fa7ee 353 SUPERFAMILY SSF48452 17 126 9.49E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS02340 d2b10433835a3951d6148497b14fa7ee 353 Gene3D G3DSA:1.25.40.10 254 322 3.3E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 SUPERFAMILY SSF51735 13 179 6.34E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 159 281 7.2E-13 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 Gene3D G3DSA:3.30.360.10 340 383 5.4E-51 T 09-03-2017 ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 Gene3D G3DSA:3.30.360.10 168 292 5.4E-51 T 09-03-2017 ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 20 139 5.6E-21 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 Gene3D G3DSA:3.40.50.720 14 167 2.2E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15635 eed43cac343596fa276359185ebe5bab 396 SUPERFAMILY SSF55347 153 321 9.16E-38 T 09-03-2017 ARZXY2_RS11495 23bb1eeb8bb7bf603e8d6b7480cc013b 151 Pfam PF07617 Protein of unknown function (DUF1579) 4 88 4.4E-5 T 09-03-2017 IPR011473 Protein of unknown function DUF1579 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 Gene3D G3DSA:3.90.228.20 340 607 2.3E-93 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 Gene3D G3DSA:3.90.228.20 247 316 2.4E-31 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 PIRSF PIRSF001348 4 608 4.4E-268 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 Gene3D G3DSA:3.40.449.10 11 246 2.4E-94 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 SUPERFAMILY SSF68923 13 246 4.92E-95 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 09-03-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 Pfam PF00821 Phosphoenolpyruvate carboxykinase 23 607 2.2E-272 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 SUPERFAMILY SSF53795 247 607 5.72E-150 T 09-03-2017 ARZXY2_RS15105 edbfc90b2050901505e586f47a1e081a 608 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 11 608 48.223 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 ARZXY2_RS20395 4e3e05b2bd9e18f8cd31a7888fbf8a50 157 Pfam PF14325 Domain of unknown function (DUF4383) 19 141 1.4E-47 T 09-03-2017 IPR025492 Protein of unknown function DUF4383 ARZXY2_RS13145 b8dee2bbaea656af7d53772be5ba7a9c 222 Pfam PF09335 SNARE associated Golgi protein 34 159 7.7E-17 T 09-03-2017 IPR032816 SNARE associated Golgi protein ARZXY2_RS07605 6401ffd89a94428ab53dfa8547b75f77 209 SUPERFAMILY SSF52833 13 169 1.04E-23 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07605 6401ffd89a94428ab53dfa8547b75f77 209 Gene3D G3DSA:3.40.30.10 13 167 2.9E-12 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS07605 6401ffd89a94428ab53dfa8547b75f77 209 Pfam PF01323 DSBA-like thioredoxin domain 15 167 1.0E-8 T 09-03-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 ARZXY2_RS10085 122914b18525b186e23443933f08bbde 318 SUPERFAMILY SSF161098 78 306 4.32E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS10085 122914b18525b186e23443933f08bbde 318 Gene3D G3DSA:1.10.3720.10 86 312 1.3E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS10085 122914b18525b186e23443933f08bbde 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 310 1.5E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04410 d76b1b06f5d3db285f23aa9e5e2db2e0 221 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 16 190 5.9E-67 T 09-03-2017 ARZXY2_RS04410 d76b1b06f5d3db285f23aa9e5e2db2e0 221 SUPERFAMILY SSF47240 17 190 2.7E-5 T 09-03-2017 IPR009078 Ferritin-like superfamily ARZXY2_RS15680 b1036efb4329c4a402cd4279c55b827b 512 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 1.8E-143 T 09-03-2017 IPR002823 Protein of unknown function DUF112, transmembrane ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 SUPERFAMILY SSF51735 11 173 2.14E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 PIRSF PIRSF000103 8 302 2.6E-60 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 Gene3D G3DSA:3.40.50.720 12 173 2.8E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 Gene3D G3DSA:1.10.1040.10 175 297 9.7E-37 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 14 27 - T 09-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 175 289 1.0E-29 T 09-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 171 1.2E-32 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 ARZXY2_RS07400 ffd927f6ed3c50ef216445722c325833 319 SUPERFAMILY SSF48179 174 295 1.36E-33 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS19635 f1aba16aca45cf9a95a3951a3bedbce4 2068 Pfam PF14040 Deoxyribonuclease NucA/NucB 1961 2064 2.9E-16 T 09-03-2017 IPR029476 Deoxyribonuclease NucA/NucB ARZXY2_RS19635 f1aba16aca45cf9a95a3951a3bedbce4 2068 Pfam PF05593 RHS Repeat 1204 1241 9.6E-7 T 09-03-2017 IPR031325 RHS repeat ARZXY2_RS19635 f1aba16aca45cf9a95a3951a3bedbce4 2068 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1749 1809 5.2E-9 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 ARZXY2_RS19635 f1aba16aca45cf9a95a3951a3bedbce4 2068 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1204 1240 1.4E-5 T 09-03-2017 IPR006530 YD repeat ARZXY2_RS02895 ee7f0802e22fae4e2b021ce1d4679abd 95 Gene3D G3DSA:1.10.10.10 5 93 3.8E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02895 ee7f0802e22fae4e2b021ce1d4679abd 95 SUPERFAMILY SSF46785 4 92 7.45E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02895 ee7f0802e22fae4e2b021ce1d4679abd 95 Pfam PF01638 HxlR-like helix-turn-helix 10 92 2.1E-18 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 86 5.9E-27 T 09-03-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 PIRSF PIRSF004669 1 89 7.0E-32 T 09-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 Pfam PF01313 Bacterial export proteins, family 3 6 77 2.8E-27 T 09-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.5E-19 T 09-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.5E-19 T 09-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 ARZXY2_RS14450 6c071eaddad6b72bc49134a517ae3e6c 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.5E-19 T 09-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 ARZXY2_RS07505 d75eada7c79854eae905fcb49755042e 186 Pfam PF00436 Single-strand binding protein family 6 104 7.4E-18 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 ARZXY2_RS07505 d75eada7c79854eae905fcb49755042e 186 Gene3D G3DSA:2.40.50.140 4 114 2.8E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS07505 d75eada7c79854eae905fcb49755042e 186 SUPERFAMILY SSF50249 4 161 2.54E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS06120 f18adc9c2875f1569cb6dc5f20a3ef11 111 Gene3D G3DSA:3.30.70.100 43 107 1.5E-16 T 09-03-2017 ARZXY2_RS06120 f18adc9c2875f1569cb6dc5f20a3ef11 111 ProSitePatterns PS01047 Heavy-metal-associated domain. 46 75 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 ARZXY2_RS06120 f18adc9c2875f1569cb6dc5f20a3ef11 111 Pfam PF00403 Heavy-metal-associated domain 45 106 7.8E-10 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS06120 f18adc9c2875f1569cb6dc5f20a3ef11 111 SUPERFAMILY SSF55008 38 107 1.3E-13 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 Gene3D G3DSA:3.40.47.10 184 350 1.4E-24 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 SUPERFAMILY SSF53901 11 214 2.29E-41 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 SUPERFAMILY SSF53901 241 350 2.29E-41 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 Gene3D G3DSA:3.40.47.10 4 183 6.9E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 262 350 1.0E-15 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS03600 5600e4a4f2e627ce477cd78b02f43e30 351 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 191 9.4E-14 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 SUPERFAMILY SSF55347 192 300 1.09E-34 T 09-03-2017 ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 6 355 3.2E-205 T 09-03-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 PIRSF PIRSF015578 1 356 4.6E-89 T 09-03-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 Gene3D G3DSA:3.40.50.720 4 191 7.5E-111 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 Gene3D G3DSA:3.40.50.720 302 356 7.5E-111 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 SUPERFAMILY SSF51735 5 187 1.38E-90 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 SUPERFAMILY SSF51735 298 357 1.38E-90 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 Pfam PF01658 Myo-inositol-1-phosphate synthase 193 301 1.1E-32 T 09-03-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 ARZXY2_RS03790 931ebad01223b5868cb1bd0f7807e906 361 Gene3D G3DSA:3.30.360.10 192 301 7.2E-48 T 09-03-2017 ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 Gene3D G3DSA:1.10.8.300 217 332 1.6E-36 T 09-03-2017 ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 SMART SM00382 49 192 0.0012 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 52 182 7.4E-60 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 Gene3D G3DSA:3.40.50.300 33 198 2.0E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 SUPERFAMILY SSF52540 27 307 2.54E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07745 fbaf16a7b27308b04a97f52b1a768f1c 335 PIRSF PIRSF002849 2 335 2.2E-121 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 Gene3D G3DSA:3.40.309.10 257 435 2.6E-66 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 Pfam PF00171 Aldehyde dehydrogenase family 7 470 2.9E-163 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 SUPERFAMILY SSF53720 2 474 4.84E-153 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS09590 d17131d9f20fd6456dc5af41c8bc8dc2 484 Gene3D G3DSA:3.40.605.10 2 256 2.6E-81 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS20580 e5e28645ea15f816abe5f2b8e128e81f 368 Gene3D G3DSA:1.10.3470.10 29 366 1.3E-81 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS20580 e5e28645ea15f816abe5f2b8e128e81f 368 Pfam PF01032 FecCD transport family 41 361 1.3E-66 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 ARZXY2_RS20580 e5e28645ea15f816abe5f2b8e128e81f 368 SUPERFAMILY SSF81345 26 361 3.27E-59 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS08695 74af32213beb6e5274c559f0f9e06c21 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 263 1.8E-81 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ARZXY2_RS08695 74af32213beb6e5274c559f0f9e06c21 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 270 18.06 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ARZXY2_RS08695 74af32213beb6e5274c559f0f9e06c21 277 Pfam PF02673 Bacitracin resistance protein BacA 6 264 4.9E-76 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 ARZXY2_RS15550 5560e3d0f09057dd71ccd3ff25f1eee8 461 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS15550 5560e3d0f09057dd71ccd3ff25f1eee8 461 SUPERFAMILY SSF103473 22 441 9.81E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15550 5560e3d0f09057dd71ccd3ff25f1eee8 461 Pfam PF00083 Sugar (and other) transporter 28 437 2.8E-34 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS15550 5560e3d0f09057dd71ccd3ff25f1eee8 461 Gene3D G3DSA:1.20.1250.20 249 440 1.7E-22 T 09-03-2017 ARZXY2_RS15550 5560e3d0f09057dd71ccd3ff25f1eee8 461 Gene3D G3DSA:1.20.1250.20 26 221 8.5E-23 T 09-03-2017 ARZXY2_RS14780 3ae9c9c8fe246ebe3518977d0355bd21 471 SUPERFAMILY SSF56112 79 235 2.24E-8 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS14780 3ae9c9c8fe246ebe3518977d0355bd21 471 Pfam PF13224 Domain of unknown function (DUF4032) 268 429 2.5E-69 T 09-03-2017 IPR025111 Domain of unknown function DUF4032 ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 Gene3D G3DSA:3.40.50.300 86 350 7.3E-94 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 SMART SM00382 151 332 3.5E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 139 348 8.5E-73 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 SUPERFAMILY SSF52540 87 353 7.11E-96 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 427 6.1E-160 T 09-03-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS14525 1f805c9dccf33c10a6b5b2e21e0f66de 437 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 ARZXY2_RS01045 eef37719f7e84153af4dc5ed3453c355 133 PIRSF PIRSF028777 1 130 9.5E-49 T 09-03-2017 IPR031308 Uncharacterised conserved protein UCP028777 ARZXY2_RS01045 eef37719f7e84153af4dc5ed3453c355 133 Pfam PF03733 Inner membrane component domain 69 119 9.3E-16 T 09-03-2017 IPR005185 Inner membrane component domain ARZXY2_RS01045 eef37719f7e84153af4dc5ed3453c355 133 Pfam PF03733 Inner membrane component domain 4 54 1.1E-17 T 09-03-2017 IPR005185 Inner membrane component domain ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.3E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.3E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.3E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 Gene3D G3DSA:3.40.50.1820 13 277 5.8E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 SUPERFAMILY SSF53474 13 278 1.08E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 Pfam PF00561 alpha/beta hydrolase fold 26 263 2.6E-32 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 1.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS01420 73574d1cfc9e9c4e978c3efb17358560 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 1.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 ARZXY2_RS19835 cf8cea1092411959b0c65ae613a2ee5b 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 283 5.8E-10 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19835 cf8cea1092411959b0c65ae613a2ee5b 295 SUPERFAMILY SSF161098 52 282 3.27E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19835 cf8cea1092411959b0c65ae613a2ee5b 295 Gene3D G3DSA:1.10.3720.10 5 284 5.0E-51 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS07235 35fb4e3b39eae8688e1cfef753f6cbe2 241 Pfam PF01638 HxlR-like helix-turn-helix 35 122 3.9E-17 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type ARZXY2_RS07235 35fb4e3b39eae8688e1cfef753f6cbe2 241 Gene3D G3DSA:1.10.10.10 25 124 3.4E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS07235 35fb4e3b39eae8688e1cfef753f6cbe2 241 SMART SM00418 31 115 0.0011 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS07235 35fb4e3b39eae8688e1cfef753f6cbe2 241 SUPERFAMILY SSF46785 24 144 1.29E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS10770 4b7ec6f00f6953098192dc593e34751f 151 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 133 62.733 T 09-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 ARZXY2_RS10770 4b7ec6f00f6953098192dc593e34751f 151 Pfam PF03477 ATP cone domain 30 115 1.4E-13 T 09-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 Gene3D G3DSA:2.40.30.10 281 371 2.6E-16 T 09-03-2017 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 368 1.3E-84 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 SUPERFAMILY SSF52402 1 244 2.09E-47 T 09-03-2017 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 Gene3D G3DSA:3.40.50.620 1 210 1.1E-75 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 Gene3D G3DSA:2.30.30.280 214 275 6.1E-16 T 09-03-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 Pfam PF03054 tRNA methyl transferase 1 368 1.2E-111 T 09-03-2017 ARZXY2_RS04675 3d4ebae1022c26f8c402960b9c0f037d 379 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 369 35.278 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 ARZXY2_RS18520 df979743992569fe13887f5f581968c2 684 Gene3D G3DSA:3.30.379.10 64 219 4.7E-13 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS18520 df979743992569fe13887f5f581968c2 684 SUPERFAMILY SSF51445 223 546 2.0E-95 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS18520 df979743992569fe13887f5f581968c2 684 Pfam PF07555 beta-N-acetylglucosaminidase 225 537 6.9E-102 T 09-03-2017 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 ARZXY2_RS18520 df979743992569fe13887f5f581968c2 684 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 71 219 6.0E-16 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 ARZXY2_RS18520 df979743992569fe13887f5f581968c2 684 SUPERFAMILY SSF55545 70 220 9.68E-11 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 ARZXY2_RS07185 13d0478c353fdf2fc4f1345452f16d9b 78 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 60 5.0E-13 T 09-03-2017 ARZXY2_RS07185 13d0478c353fdf2fc4f1345452f16d9b 78 SUPERFAMILY SSF54862 4 61 6.8E-9 T 09-03-2017 ARZXY2_RS07185 13d0478c353fdf2fc4f1345452f16d9b 78 Gene3D G3DSA:3.30.70.20 3 68 1.2E-14 T 09-03-2017 ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 Pfam PF07729 FCD domain 89 206 2.2E-19 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 SMART SM00895 85 207 8.8E-14 T 09-03-2017 IPR011711 GntR, C-terminal ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 Gene3D G3DSA:1.20.120.530 80 206 1.3E-20 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 2.4E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 SMART SM00345 17 75 9.6E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 Gene3D G3DSA:1.10.10.10 4 76 9.7E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 SUPERFAMILY SSF48008 81 207 1.02E-21 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal ARZXY2_RS19275 e00e99f4d49161a6317f6ff7c920cc3c 226 SUPERFAMILY SSF46785 7 79 1.46E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02375 87b264ea2f3848a6a7793de0200e56ee 342 SUPERFAMILY SSF54106 150 195 1.44E-9 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS02375 87b264ea2f3848a6a7793de0200e56ee 342 Pfam PF01476 LysM domain 152 194 5.0E-12 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS02375 87b264ea2f3848a6a7793de0200e56ee 342 SMART SM00257 151 195 7.8E-12 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS02375 87b264ea2f3848a6a7793de0200e56ee 342 Gene3D G3DSA:3.10.350.10 151 195 7.9E-14 T 09-03-2017 IPR018392 LysM domain ARZXY2_RS07945 5be7d54fac5b29cf946b761051b1ee54 415 Gene3D G3DSA:3.60.21.10 129 328 3.2E-16 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS07945 5be7d54fac5b29cf946b761051b1ee54 415 SMART SM00854 77 323 1.0E-77 T 09-03-2017 IPR019079 Capsule synthesis protein, CapA ARZXY2_RS07945 5be7d54fac5b29cf946b761051b1ee54 415 SUPERFAMILY SSF56300 80 339 6.17E-28 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS07945 5be7d54fac5b29cf946b761051b1ee54 415 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 78 320 1.7E-63 T 09-03-2017 IPR019079 Capsule synthesis protein, CapA ARZXY2_RS08250 4de29aabf1aa83fdddb7bdf6038c4132 182 SUPERFAMILY SSF50118 71 176 7.85E-9 T 09-03-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor ARZXY2_RS08250 4de29aabf1aa83fdddb7bdf6038c4132 182 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 75 177 7.6E-7 T 09-03-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 ARZXY2_RS09345 edf0de75e4213922e83477d0304b2773 209 Gene3D G3DSA:3.40.430.10 13 196 1.0E-15 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS09345 edf0de75e4213922e83477d0304b2773 209 SUPERFAMILY SSF53597 14 201 3.93E-22 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS09345 edf0de75e4213922e83477d0304b2773 209 Pfam PF01872 RibD C-terminal domain 12 191 1.8E-24 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS10620 2ac58ca1cf33577fd39862ccb19f785c 358 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 196 1.6E-64 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ARZXY2_RS10620 2ac58ca1cf33577fd39862ccb19f785c 358 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 321 5.4E-103 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ARZXY2_RS10620 2ac58ca1cf33577fd39862ccb19f785c 358 PIRSF PIRSF000267 1 336 2.8E-117 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 09-03-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 SUPERFAMILY SSF100950 8 225 1.2E-81 T 09-03-2017 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 219 2.2E-78 T 09-03-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 Gene3D G3DSA:3.40.1080.10 3 217 2.0E-92 T 09-03-2017 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 Pfam PF01144 Coenzyme A transferase 10 216 7.9E-73 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS16520 9cf806ed84fb3994f10d6fc5e0a2447f 242 SMART SM00882 5 217 5.0E-85 T 09-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 ARZXY2_RS16430 d96ae5915ac8ee644b015d6202afaaf8 249 Gene3D G3DSA:3.40.50.300 10 240 9.4E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16430 d96ae5915ac8ee644b015d6202afaaf8 249 SUPERFAMILY SSF52540 11 245 8.37E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS16430 d96ae5915ac8ee644b015d6202afaaf8 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 245 4.7E-8 T 09-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal ARZXY2_RS16430 d96ae5915ac8ee644b015d6202afaaf8 249 SMART SM00382 37 223 0.001 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS16430 d96ae5915ac8ee644b015d6202afaaf8 249 Pfam PF00005 ABC transporter 28 174 6.9E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS08580 928e3e65c3f639a3a3f92c29d58e1482 153 SUPERFAMILY SSF141322 84 145 2.62E-8 T 09-03-2017 ARZXY2_RS08580 928e3e65c3f639a3a3f92c29d58e1482 153 Gene3D G3DSA:2.40.50.140 88 145 4.7E-20 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS08580 928e3e65c3f639a3a3f92c29d58e1482 153 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 146 1.7E-19 T 09-03-2017 IPR002810 NfeD-like, C-terminal domain ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 SUPERFAMILY SSF46689 13 78 1.59E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 SUPERFAMILY SSF48498 89 197 6.12E-20 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 Gene3D G3DSA:1.10.357.10 65 198 7.0E-41 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 6.3E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS02315 f8f15beeceef80b86a9a458c2a9f3ba3 200 Gene3D G3DSA:1.10.10.60 3 64 1.0E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS14550 9e01393c3e95865f3ad426d427f5f580 130 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 54 124 5.5E-7 T 09-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain ARZXY2_RS00635 5568c57ab6365245407050f16fd19840 868 Pfam PF04865 Baseplate J-like protein 264 442 5.4E-10 T 09-03-2017 IPR006949 Baseplate protein J-like ARZXY2_RS00635 5568c57ab6365245407050f16fd19840 868 Gene3D G3DSA:2.130.10.140 499 592 3.6E-11 T 09-03-2017 ARZXY2_RS00635 5568c57ab6365245407050f16fd19840 868 Gene3D G3DSA:2.130.10.140 642 688 3.6E-11 T 09-03-2017 ARZXY2_RS00635 5568c57ab6365245407050f16fd19840 868 Gene3D G3DSA:2.130.10.140 753 839 3.6E-11 T 09-03-2017 ARZXY2_RS00635 5568c57ab6365245407050f16fd19840 868 SUPERFAMILY SSF110296 504 675 8.89E-10 T 09-03-2017 ARZXY2_RS09950 c8994006c963f82e9b4e9f26f7daaa7e 140 SUPERFAMILY SSF49764 21 127 1.53E-28 T 09-03-2017 IPR008978 HSP20-like chaperone ARZXY2_RS09950 c8994006c963f82e9b4e9f26f7daaa7e 140 Pfam PF00011 Hsp20/alpha crystallin family 38 137 1.1E-19 T 09-03-2017 IPR002068 Alpha crystallin/Hsp20 domain ARZXY2_RS09950 c8994006c963f82e9b4e9f26f7daaa7e 140 Gene3D G3DSA:2.60.40.790 21 137 6.5E-28 T 09-03-2017 IPR008978 HSP20-like chaperone ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 110 2.3E-33 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 SMART SM00922 129 264 6.1E-19 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 Gene3D G3DSA:3.30.390.10 2 119 2.3E-48 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 SUPERFAMILY SSF51604 98 393 1.57E-73 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 Gene3D G3DSA:3.20.20.120 120 372 6.7E-81 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 Pfam PF13378 Enolase C-terminal domain-like 200 384 7.4E-44 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 ARZXY2_RS16205 4f1a3891687741dde9700680b23308b5 409 SUPERFAMILY SSF54826 9 112 6.27E-34 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS07760 56b6beef00d6d9301652a4d6437e1c18 333 SMART SM00327 90 291 1.4E-5 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07760 56b6beef00d6d9301652a4d6437e1c18 333 Pfam PF00092 von Willebrand factor type A domain 92 282 7.9E-10 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07760 56b6beef00d6d9301652a4d6437e1c18 333 Gene3D G3DSA:3.40.50.410 88 291 4.4E-20 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS07760 56b6beef00d6d9301652a4d6437e1c18 333 SUPERFAMILY SSF53300 87 291 1.38E-21 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS13790 b3d46ac0c7815cca8753bd298ef38a23 239 SUPERFAMILY SSF51351 1 233 3.01E-57 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS13790 b3d46ac0c7815cca8753bd298ef38a23 239 Gene3D G3DSA:3.20.20.70 1 234 1.1E-63 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS13790 b3d46ac0c7815cca8753bd298ef38a23 239 Pfam PF00121 Triosephosphate isomerase 4 229 7.5E-48 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 ARZXY2_RS10340 77bb905679c03205c70eba0caa2d1222 230 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 24 213 4.2E-19 T 09-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ARZXY2_RS10340 77bb905679c03205c70eba0caa2d1222 230 Pfam PF04973 Nicotinamide mononucleotide transporter 22 210 4.8E-50 T 09-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 SUPERFAMILY SSF53098 141 320 1.39E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 SUPERFAMILY SSF46689 4 85 1.97E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 Pfam PF00665 Integrase core domain 139 276 4.4E-32 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 Gene3D G3DSA:1.10.10.60 13 61 7.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 Gene3D G3DSA:3.30.420.10 135 313 2.3E-43 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS11000 e1c678b49e27b320849b87890fbeb946 325 Pfam PF13011 leucine-zipper of insertion element IS481 5 82 2.9E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type ARZXY2_RS20605 e1a814c66ae30afc5be3d0aefefe2a42 256 SUPERFAMILY SSF52266 5 193 5.5E-37 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS20605 e1a814c66ae30afc5be3d0aefefe2a42 256 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 181 1.9E-24 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS20605 e1a814c66ae30afc5be3d0aefefe2a42 256 Gene3D G3DSA:3.40.50.1110 6 194 5.3E-39 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 297 494 2.6E-40 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 Hamap MF_00520 Ribulokinase [araB]. 11 551 46.9 T 09-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 Gene3D G3DSA:3.30.420.40 290 536 4.6E-55 T 09-03-2017 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 Gene3D G3DSA:3.30.420.40 10 283 5.5E-41 T 09-03-2017 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 SUPERFAMILY SSF53067 290 540 1.9E-60 T 09-03-2017 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 SUPERFAMILY SSF53067 13 288 2.27E-36 T 09-03-2017 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 PIRSF PIRSF000538 11 541 9.3E-61 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 282 1.9E-10 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 ARZXY2_RS00235 2e8c0d19b341705c7da20fd05e05ce5d 588 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 13 544 1.8E-251 T 09-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 ARZXY2_RS14810 6c2e5678a063c86a404433de208414a6 164 SUPERFAMILY SSF55961 23 159 2.35E-28 T 09-03-2017 ARZXY2_RS14810 6c2e5678a063c86a404433de208414a6 164 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 34 153 1.1E-5 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 ARZXY2_RS14810 6c2e5678a063c86a404433de208414a6 164 Gene3D G3DSA:3.30.530.20 23 154 4.1E-11 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 58 439 1.2E-122 T 09-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 57 439 2.1E-120 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 SUPERFAMILY SSF51713 55 144 2.49E-128 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 SUPERFAMILY SSF51713 171 439 2.49E-128 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 29 433 45.761 T 09-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 Pfam PF01702 Queuine tRNA-ribosyltransferase 198 434 1.3E-79 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS15520 3fb5cdfeb1b9c29ae24509c65b3e166e 441 Gene3D G3DSA:3.20.20.105 57 440 2.4E-140 T 09-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 ARZXY2_RS13080 34e15430e2871d354cef881347ed4f5b 285 Pfam PF01636 Phosphotransferase enzyme family 35 230 3.2E-13 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase ARZXY2_RS13080 34e15430e2871d354cef881347ed4f5b 285 SUPERFAMILY SSF56112 32 276 4.72E-24 T 09-03-2017 IPR011009 Protein kinase-like domain ARZXY2_RS13080 34e15430e2871d354cef881347ed4f5b 285 Gene3D G3DSA:3.90.1200.10 102 244 5.6E-15 T 09-03-2017 ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 SUPERFAMILY SSF52402 5 140 1.59E-26 T 09-03-2017 ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 Pfam PF00582 Universal stress protein family 3 137 8.1E-23 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 PRINTS PR01438 Universal stress protein signature 116 138 7.8E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 PRINTS PR01438 Universal stress protein signature 99 111 7.8E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 PRINTS PR01438 Universal stress protein signature 2 20 7.8E-12 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS20055 ac5cc1aec8a790ef8209053111282287 142 Gene3D G3DSA:3.40.50.620 5 137 2.9E-28 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 Gene3D G3DSA:1.20.1250.20 252 442 1.3E-11 T 09-03-2017 ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 Gene3D G3DSA:1.20.1250.20 46 236 2.3E-21 T 09-03-2017 ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 SUPERFAMILY SSF103473 23 445 4.84E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 Pfam PF00083 Sugar (and other) transporter 306 447 3.2E-6 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS07390 bb97aded87922464477fdeb12e7cd701 452 Pfam PF00083 Sugar (and other) transporter 30 235 1.1E-24 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 Pfam PF07690 Major Facilitator Superfamily 28 367 1.8E-40 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 392 9.2E-80 T 09-03-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 Gene3D G3DSA:1.20.1250.20 18 204 6.7E-24 T 09-03-2017 ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 Gene3D G3DSA:1.20.1250.20 221 399 3.4E-11 T 09-03-2017 ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 SUPERFAMILY SSF103473 13 403 3.27E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS12140 2961e9a15240946ce6fff59951c0daac 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 92 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 ARZXY2_RS22665 d5cf89c4019ca913d8b076fec9cc2d91 305 Pfam PF05425 Copper resistance protein D 24 123 1.4E-21 T 09-03-2017 IPR008457 Copper resistance protein D GO:0016021 ARZXY2_RS22665 d5cf89c4019ca913d8b076fec9cc2d91 305 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 178 304 1.8E-38 T 09-03-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related ARZXY2_RS12470 e458c102cf5f758c3b7130bea4367d3d 304 Pfam PF03099 Biotin/lipoate A/B protein ligase family 62 177 2.5E-14 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 ARZXY2_RS12470 e458c102cf5f758c3b7130bea4367d3d 304 Gene3D G3DSA:3.30.930.10 37 226 1.4E-51 T 09-03-2017 ARZXY2_RS12470 e458c102cf5f758c3b7130bea4367d3d 304 SUPERFAMILY SSF50037 250 295 6.68E-5 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal ARZXY2_RS12470 e458c102cf5f758c3b7130bea4367d3d 304 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 41 295 4.2E-38 T 09-03-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 ARZXY2_RS12470 e458c102cf5f758c3b7130bea4367d3d 304 SUPERFAMILY SSF55681 38 227 5.14E-45 T 09-03-2017 ARZXY2_RS07875 85b324f6abfd6ed63c718eb798159d7a 223 SMART SM00849 28 202 3.3E-32 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07875 85b324f6abfd6ed63c718eb798159d7a 223 Gene3D G3DSA:3.60.15.10 28 207 1.0E-48 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07875 85b324f6abfd6ed63c718eb798159d7a 223 SUPERFAMILY SSF56281 13 214 2.03E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS07875 85b324f6abfd6ed63c718eb798159d7a 223 Pfam PF00753 Metallo-beta-lactamase superfamily 28 202 2.0E-21 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS04220 c6688598902c6aeb794d43ba854c6780 314 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 69 4.9E-9 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain ARZXY2_RS04220 c6688598902c6aeb794d43ba854c6780 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 312 2.0E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04220 c6688598902c6aeb794d43ba854c6780 314 Gene3D G3DSA:1.10.3720.10 101 309 1.2E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04220 c6688598902c6aeb794d43ba854c6780 314 SUPERFAMILY SSF161098 102 295 6.54E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11470 70f65646afb82fb8e381519d219bc76e 516 SUPERFAMILY SSF56524 224 413 8.11E-53 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS11470 70f65646afb82fb8e381519d219bc76e 516 Gene3D G3DSA:2.60.40.650 411 515 1.1E-18 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 ARZXY2_RS11470 70f65646afb82fb8e381519d219bc76e 516 Gene3D G3DSA:3.90.420.10 215 410 6.3E-49 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS11470 70f65646afb82fb8e381519d219bc76e 516 SUPERFAMILY SSF81296 406 515 1.68E-21 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS11470 70f65646afb82fb8e381519d219bc76e 516 Pfam PF00174 Oxidoreductase molybdopterin binding domain 243 388 2.1E-34 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 ARZXY2_RS08990 2253d263d2de08f39a0799aa22d7557f 118 Pfam PF00355 Rieske [2Fe-2S] domain 10 93 1.6E-17 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS08990 2253d263d2de08f39a0799aa22d7557f 118 SUPERFAMILY SSF50022 9 107 3.01E-28 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS08990 2253d263d2de08f39a0799aa22d7557f 118 Gene3D G3DSA:2.102.10.10 10 108 1.0E-27 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS10310 0708a91eacc36249fd5bd7eb5445ec81 87 SUPERFAMILY SSF101386 3 87 2.24E-21 T 09-03-2017 ARZXY2_RS10310 0708a91eacc36249fd5bd7eb5445ec81 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 2 86 6.0E-9 T 09-03-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 ARZXY2_RS10310 0708a91eacc36249fd5bd7eb5445ec81 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 2.1E-23 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 ARZXY2_RS10310 0708a91eacc36249fd5bd7eb5445ec81 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 18.295 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 ARZXY2_RS05805 a45deaa55870af1827f4497fd2ed40ec 219 Gene3D G3DSA:3.40.50.150 2 216 3.6E-49 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS05805 a45deaa55870af1827f4497fd2ed40ec 219 SUPERFAMILY SSF53335 11 197 1.36E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS09440 5ba97a0090565e65c5d5e1f91ef5900b 160 SUPERFAMILY SSF51182 22 143 1.04E-19 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS09440 5ba97a0090565e65c5d5e1f91ef5900b 160 Gene3D G3DSA:2.60.120.10 27 148 1.4E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS09440 5ba97a0090565e65c5d5e1f91ef5900b 160 Pfam PF07883 Cupin domain 69 135 1.4E-8 T 09-03-2017 IPR013096 Cupin 2, conserved barrel ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 Pfam PF07690 Major Facilitator Superfamily 27 204 1.0E-30 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 Pfam PF07690 Major Facilitator Superfamily 279 456 6.3E-13 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 Gene3D G3DSA:1.20.1250.20 19 200 2.6E-27 T 09-03-2017 ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 SUPERFAMILY SSF103473 256 463 7.32E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 SUPERFAMILY SSF103473 20 211 7.32E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15075 493fad5ce5b9dcb3018e7d93e9dcc06a 479 Gene3D G3DSA:1.20.1250.20 272 463 2.5E-16 T 09-03-2017 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 Gene3D G3DSA:2.40.30.20 105 205 2.3E-30 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 Gene3D G3DSA:2.40.30.20 5 104 1.8E-30 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 PIRSF PIRSF000498 1 216 4.8E-67 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 Pfam PF00677 Lumazine binding domain 3 86 5.3E-20 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 Pfam PF00677 Lumazine binding domain 100 189 8.0E-22 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 200 4.6E-61 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 SUPERFAMILY SSF63380 94 204 4.85E-30 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS10330 41799249a48aa5e748af47e56f1965a3 231 SUPERFAMILY SSF63380 1 88 3.49E-23 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 ARZXY2_RS19910 33444d34e88d30c9923ab5b6238f3316 120 Gene3D G3DSA:3.10.450.50 8 115 1.6E-12 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS19910 33444d34e88d30c9923ab5b6238f3316 120 SUPERFAMILY SSF54427 5 115 2.67E-17 T 09-03-2017 IPR032710 NTF2-like domain ARZXY2_RS19910 33444d34e88d30c9923ab5b6238f3316 120 Pfam PF12680 SnoaL-like domain 11 109 6.0E-12 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain ARZXY2_RS01400 df1f276febcecc5f6753a1619bc4f80f 111 Gene3D G3DSA:2.30.30.240 1 67 8.9E-6 T 09-03-2017 ARZXY2_RS19795 0fce6df47900e339cb5d9cb65ceb2479 197 SUPERFAMILY SSF53254 4 189 2.9E-45 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS19795 0fce6df47900e339cb5d9cb65ceb2479 197 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 11 20 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ARZXY2_RS19795 0fce6df47900e339cb5d9cb65ceb2479 197 SMART SM00855 8 153 1.2E-22 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS19795 0fce6df47900e339cb5d9cb65ceb2479 197 Gene3D G3DSA:3.40.50.1240 4 187 5.7E-46 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS19795 0fce6df47900e339cb5d9cb65ceb2479 197 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 10 176 1.8E-43 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 Pfam PF01546 Peptidase family M20/M25/M40 60 362 1.2E-19 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 Pfam PF07687 Peptidase dimerisation domain 183 280 1.2E-10 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 SUPERFAMILY SSF55031 182 287 3.79E-26 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 SUPERFAMILY SSF53187 298 401 6.6E-72 T 09-03-2017 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 SUPERFAMILY SSF53187 3 195 6.6E-72 T 09-03-2017 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 Gene3D G3DSA:3.30.70.360 179 297 5.7E-35 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 PIRSF PIRSF005962 2 378 1.9E-96 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 Gene3D G3DSA:3.40.630.10 2 176 2.3E-81 T 09-03-2017 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 Gene3D G3DSA:3.40.630.10 298 401 2.3E-81 T 09-03-2017 ARZXY2_RS14565 a592bbcbc4226c02b55c7d87fd5041a9 402 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 6 339 2.3E-85 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 ARZXY2_RS14350 fde0776c47d12573a134d46a67fb0495 495 Pfam PF12821 Threonine/Serine exporter, ThrE 346 473 1.6E-14 T 09-03-2017 IPR024528 Threonine/Serine exporter, ThrE ARZXY2_RS14350 fde0776c47d12573a134d46a67fb0495 495 Pfam PF06738 Putative threonine/serine exporter 82 322 2.1E-57 T 09-03-2017 IPR010619 Putative threonine/serine exporter ARZXY2_RS13835 7b11ba4db4d6086e51cb30c784752d4c 194 Pfam PF13580 SIS domain 31 147 5.0E-8 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS13835 7b11ba4db4d6086e51cb30c784752d4c 194 Gene3D G3DSA:3.40.50.10490 29 189 2.4E-25 T 09-03-2017 ARZXY2_RS13835 7b11ba4db4d6086e51cb30c784752d4c 194 SUPERFAMILY SSF53697 28 188 5.26E-21 T 09-03-2017 ARZXY2_RS08345 47838a62ab0c01b272e01702abc325c4 357 Gene3D G3DSA:3.40.50.1820 73 355 5.9E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08345 47838a62ab0c01b272e01702abc325c4 357 SUPERFAMILY SSF53474 69 354 3.59E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08345 47838a62ab0c01b272e01702abc325c4 357 Pfam PF12146 Serine aminopeptidase, S33 79 308 1.6E-18 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 250 271 - T 09-03-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 SUPERFAMILY SSF54593 15 330 1.2E-44 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 Gene3D G3DSA:3.10.180.10 156 293 2.7E-41 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 18 313 6.3E-135 T 09-03-2017 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 Gene3D G3DSA:3.10.180.10 17 140 1.8E-38 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 156 272 1.7E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS09380 039d7e18b20a85500fa53c5621467dd8 363 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 129 9.2E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS04075 a684be3dc37d88c26e2bbec9064e67eb 338 Gene3D G3DSA:2.60.120.10 33 264 1.8E-58 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS04075 a684be3dc37d88c26e2bbec9064e67eb 338 Pfam PF05726 Pirin C-terminal cupin domain 199 289 9.1E-19 T 09-03-2017 IPR008778 Pirin, C-terminal domain ARZXY2_RS04075 a684be3dc37d88c26e2bbec9064e67eb 338 Pfam PF02678 Pirin 41 142 1.1E-23 T 09-03-2017 IPR003829 Pirin, N-terminal domain ARZXY2_RS04075 a684be3dc37d88c26e2bbec9064e67eb 338 SUPERFAMILY SSF51182 39 289 1.4E-62 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS17385 cec214098cfde56e8f5020b4bd94804f 444 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 9 344 8.4E-126 T 09-03-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase ARZXY2_RS17385 cec214098cfde56e8f5020b4bd94804f 444 SUPERFAMILY SSF51905 276 377 7.07E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17385 cec214098cfde56e8f5020b4bd94804f 444 SUPERFAMILY SSF51905 188 244 7.07E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17385 cec214098cfde56e8f5020b4bd94804f 444 SUPERFAMILY SSF51905 9 275 7.92E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17385 cec214098cfde56e8f5020b4bd94804f 444 Gene3D G3DSA:3.50.50.60 89 233 4.0E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17490 6394f6c5ff720e1eec49a302fe2890dc 263 Gene3D G3DSA:3.50.30.50 16 256 5.6E-53 T 09-03-2017 ARZXY2_RS17490 6394f6c5ff720e1eec49a302fe2890dc 263 SUPERFAMILY SSF102198 16 255 6.15E-48 T 09-03-2017 ARZXY2_RS17490 6394f6c5ff720e1eec49a302fe2890dc 263 Pfam PF04199 Putative cyclase 19 194 3.5E-31 T 09-03-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 ARZXY2_RS20620 f4d353e7a8b9f7c38277a7447b72f85e 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 3.7E-24 T 09-03-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS20620 f4d353e7a8b9f7c38277a7447b72f85e 101 SUPERFAMILY SSF57716 2 101 2.71E-34 T 09-03-2017 ARZXY2_RS20620 f4d353e7a8b9f7c38277a7447b72f85e 101 Gene3D G3DSA:4.10.830.10 43 101 2.4E-28 T 09-03-2017 ARZXY2_RS20620 f4d353e7a8b9f7c38277a7447b72f85e 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.77 T 09-03-2017 IPR023036 Ribosomal protein S14, bacterial/plastid ARZXY2_RS12155 443af4540e39139b8cb5c0e764e222db 427 Pfam PF00756 Putative esterase 190 321 1.2E-6 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 ARZXY2_RS12155 443af4540e39139b8cb5c0e764e222db 427 Gene3D G3DSA:3.40.50.1820 166 418 2.1E-30 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12155 443af4540e39139b8cb5c0e764e222db 427 SUPERFAMILY SSF53474 171 413 1.23E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS18665 703501bc9a200f7e23029d961b7155c8 232 Gene3D G3DSA:3.40.50.300 3 223 1.5E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18665 703501bc9a200f7e23029d961b7155c8 232 Pfam PF00005 ABC transporter 23 172 2.9E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS18665 703501bc9a200f7e23029d961b7155c8 232 SMART SM00382 32 220 1.9E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS18665 703501bc9a200f7e23029d961b7155c8 232 SUPERFAMILY SSF52540 5 225 1.04E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18665 703501bc9a200f7e23029d961b7155c8 232 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS17050 caa49df64a1f2d39d31ff3e93fcd347d 363 SUPERFAMILY SSF52540 3 267 7.99E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17050 caa49df64a1f2d39d31ff3e93fcd347d 363 Gene3D G3DSA:3.40.50.300 35 203 3.1E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17050 caa49df64a1f2d39d31ff3e93fcd347d 363 Pfam PF13191 AAA ATPase domain 16 161 2.8E-10 T 09-03-2017 ARZXY2_RS14225 6a33874864285c5a84e4e2cad71f4ec3 262 Pfam PF00877 NlpC/P60 family 169 237 5.4E-10 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS14225 6a33874864285c5a84e4e2cad71f4ec3 262 SUPERFAMILY SSF54001 147 250 3.63E-15 T 09-03-2017 ARZXY2_RS14225 6a33874864285c5a84e4e2cad71f4ec3 262 Gene3D G3DSA:3.90.1720.10 154 250 1.3E-12 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 53 69 1.9E-14 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 10 27 1.9E-14 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 87 102 1.9E-14 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 135 150 1.9E-14 T 09-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 Gene3D G3DSA:3.40.50.270 6 167 2.5E-42 T 09-03-2017 ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 SMART SM00226 8 163 4.7E-30 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 157 1.3E-32 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS00500 a9e29ae5b47b27408495da8935054181 190 SUPERFAMILY SSF52788 6 164 2.09E-39 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 Pfam PF01250 Ribosomal protein S6 4 92 3.9E-29 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 Gene3D G3DSA:3.30.70.60 1 95 9.9E-35 T 09-03-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.2E-25 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 SUPERFAMILY SSF54995 1 96 1.18E-32 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 09-03-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS18780 2fd98746ec1c5c13440eba335428909a 101 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.059 T 09-03-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 ARZXY2_RS05465 86d6d0fe7fc8d11f5188c993cdd58f5c 444 Pfam PF00083 Sugar (and other) transporter 27 239 3.9E-24 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 ARZXY2_RS05465 86d6d0fe7fc8d11f5188c993cdd58f5c 444 Gene3D G3DSA:1.20.1250.20 26 232 1.1E-20 T 09-03-2017 ARZXY2_RS05465 86d6d0fe7fc8d11f5188c993cdd58f5c 444 Gene3D G3DSA:1.20.1250.20 250 435 2.5E-24 T 09-03-2017 ARZXY2_RS05465 86d6d0fe7fc8d11f5188c993cdd58f5c 444 Pfam PF07690 Major Facilitator Superfamily 258 431 8.6E-15 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS05465 86d6d0fe7fc8d11f5188c993cdd58f5c 444 SUPERFAMILY SSF103473 15 438 3.53E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 224 1.1E-5 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 321 495 5.0E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 Gene3D G3DSA:1.10.3720.10 2 231 9.7E-31 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 SUPERFAMILY SSF161098 3 229 3.66E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 Gene3D G3DSA:1.10.3720.10 263 489 2.0E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15440 62ee5dd848987e6412e2cb8b8e341dff 499 SUPERFAMILY SSF161098 260 490 3.01E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 Gene3D G3DSA:3.40.1400.10 2 141 1.5E-46 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 Pfam PF02502 Ribose/Galactose Isomerase 2 135 7.1E-39 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 2 140 4.5E-43 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 PIRSF PIRSF005384 1 142 7.7E-40 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 SUPERFAMILY SSF89623 2 142 1.96E-43 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 ARZXY2_RS07565 b8fc3ae473ea6603983284f692993920 146 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 2 141 7.4E-55 T 09-03-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 ARZXY2_RS12215 b2d0efe6b62fd4ea9c962332f3a5779d 215 SUPERFAMILY SSF53474 12 210 1.21E-38 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS12215 b2d0efe6b62fd4ea9c962332f3a5779d 215 Pfam PF02230 Phospholipase/Carboxylesterase 20 210 1.5E-9 T 09-03-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 ARZXY2_RS12215 b2d0efe6b62fd4ea9c962332f3a5779d 215 Gene3D G3DSA:3.40.50.1820 13 212 5.5E-49 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 Pfam PF00574 Clp protease 33 209 6.7E-74 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 2.3E-42 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 2.3E-42 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 2.3E-42 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 PRINTS PR00127 Clp protease catalytic subunit P signature 185 204 2.3E-42 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 2.3E-42 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 127 140 - T 09-03-2017 IPR033135 ClpP, histidine active site ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 105 116 - T 09-03-2017 IPR018215 ClpP, Ser active site ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 SUPERFAMILY SSF52096 26 212 2.54E-62 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 210 40.0 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 ARZXY2_RS07595 6242fcf061d25d42d2d29c21dc539832 219 Gene3D G3DSA:3.90.226.10 19 209 9.5E-74 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 SUPERFAMILY SSF46785 21 113 6.62E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 3.7E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 Gene3D G3DSA:1.10.10.10 10 113 5.1E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.4E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 4.4E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 4.4E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 4.4E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS06660 db23cd9daeea43703652b34dafbead25 116 SMART SM00418 34 114 5.0E-25 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 ARZXY2_RS00130 d2e452db8dd9ea0a840d8a27313c587f 113 SUPERFAMILY SSF52821 10 112 4.06E-31 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00130 d2e452db8dd9ea0a840d8a27313c587f 113 SMART SM00450 18 111 1.4E-21 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00130 d2e452db8dd9ea0a840d8a27313c587f 113 Gene3D G3DSA:3.40.250.10 10 112 6.9E-31 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS00130 d2e452db8dd9ea0a840d8a27313c587f 113 Pfam PF00581 Rhodanese-like domain 20 107 2.7E-14 T 09-03-2017 IPR001763 Rhodanese-like domain ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 70 7.0E-25 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 SUPERFAMILY SSF82697 4 74 5.58E-22 T 09-03-2017 ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 18.933 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 Gene3D G3DSA:3.30.1280.10 3 78 2.7E-28 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 6 75 1.9E-14 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS15905 4533a276d2ebf7bf7d94729e6d37a95f 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 9.2E-25 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 ARZXY2_RS00090 ba32343855612526801d7625f9c50dd8 355 Gene3D G3DSA:3.20.20.30 18 340 1.8E-58 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00090 ba32343855612526801d7625f9c50dd8 355 SUPERFAMILY SSF51679 23 339 2.02E-46 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00090 ba32343855612526801d7625f9c50dd8 355 Pfam PF00296 Luciferase-like monooxygenase 10 292 8.9E-20 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00580 c4348d452aaca6f2672599bb46a70236 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 4.2E-24 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS00580 c4348d452aaca6f2672599bb46a70236 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 55 1.8E-15 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS00580 c4348d452aaca6f2672599bb46a70236 91 SUPERFAMILY SSF143120 1 81 2.88E-25 T 09-03-2017 ARZXY2_RS00580 c4348d452aaca6f2672599bb46a70236 91 Gene3D G3DSA:3.40.1620.10 1 50 7.9E-15 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM ARZXY2_RS08660 3dabeff59d078d8487fbafed0dbc69dd 538 Pfam PF03136 Pup-ligase protein 2 485 3.3E-176 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 ARZXY2_RS08660 3dabeff59d078d8487fbafed0dbc69dd 538 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 513 2.8E-197 T 09-03-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 ARZXY2_RS09255 0ed8805ba0999a361a4056028f1ea522 290 Pfam PF12730 ABC-2 family transporter protein 27 220 3.9E-10 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 ARZXY2_RS08500 a7a09a5dd4b64f6e2238db8398cf99a9 126 Pfam PF16259 Domain of unknown function (DUF4913) 19 114 7.5E-25 T 09-03-2017 IPR032584 Protein of unknown function DUF4913 ARZXY2_RS20495 b53d09832821a8c57d7e785789e3bd6d 153 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 7 90 4.0E-22 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane ARZXY2_RS20495 b53d09832821a8c57d7e785789e3bd6d 153 Pfam PF12823 Domain of unknown function (DUF3817) 6 92 1.2E-21 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 533 2.8E-21 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 SUPERFAMILY SSF52518 367 543 1.2E-36 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Gene3D G3DSA:3.40.50.970 379 542 2.5E-35 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 SUPERFAMILY SSF52518 14 186 8.34E-36 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Gene3D G3DSA:3.40.50.970 12 194 4.3E-42 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 SUPERFAMILY SSF52467 166 361 8.18E-37 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 202 332 5.3E-25 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 182 1.9E-40 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 ARZXY2_RS09555 621591d9e39a6024846fcdaf35ea2b63 556 Gene3D G3DSA:3.40.50.1220 196 378 8.3E-39 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain ARZXY2_RS13640 61c5f3a9f02b4bc280be7313c5c7208c 325 Pfam PF14100 Methane oxygenase PmoA 22 314 3.8E-70 T 09-03-2017 IPR029475 Methane oxygenase PmoA ARZXY2_RS08550 91c2e556dfe14d4612743c0a4a18c1cd 236 Pfam PF13649 Methyltransferase domain 65 153 3.8E-12 T 09-03-2017 ARZXY2_RS08550 91c2e556dfe14d4612743c0a4a18c1cd 236 SUPERFAMILY SSF53335 24 184 5.36E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS08550 91c2e556dfe14d4612743c0a4a18c1cd 236 Gene3D G3DSA:3.40.50.150 45 175 1.2E-19 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS00320 9ca52c3e4fa1501e21bd7c25f3fdc926 147 SUPERFAMILY SSF55961 6 142 2.32E-15 T 09-03-2017 ARZXY2_RS00320 9ca52c3e4fa1501e21bd7c25f3fdc926 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 136 2.3E-8 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase ARZXY2_RS00320 9ca52c3e4fa1501e21bd7c25f3fdc926 147 Gene3D G3DSA:3.30.530.20 10 135 6.4E-4 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS14805 24cf1a25c97edf6693c2feb761337732 162 Pfam PF00583 Acetyltransferase (GNAT) family 49 127 3.1E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS14805 24cf1a25c97edf6693c2feb761337732 162 Gene3D G3DSA:3.40.630.30 19 153 1.1E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14805 24cf1a25c97edf6693c2feb761337732 162 SUPERFAMILY SSF55729 19 149 1.42E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS13295 5f828852b4c32f3d556c826baa9436ea 219 Gene3D G3DSA:3.40.50.150 13 190 2.8E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS13295 5f828852b4c32f3d556c826baa9436ea 219 Pfam PF08241 Methyltransferase domain 52 137 1.8E-15 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 ARZXY2_RS13295 5f828852b4c32f3d556c826baa9436ea 219 SUPERFAMILY SSF53335 10 181 4.15E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS14575 b65862323becc03e73b078ce9986eab6 146 Gene3D G3DSA:1.20.120.340 9 125 2.6E-30 T 09-03-2017 IPR003713 Flagellar protein FliS GO:0044780 ARZXY2_RS14575 b65862323becc03e73b078ce9986eab6 146 Pfam PF02561 Flagellar protein FliS 12 123 3.0E-29 T 09-03-2017 IPR003713 Flagellar protein FliS GO:0044780 ARZXY2_RS14575 b65862323becc03e73b078ce9986eab6 146 TIGRFAM TIGR00208 fliS: flagellar protein FliS 9 123 7.7E-18 T 09-03-2017 IPR003713 Flagellar protein FliS GO:0044780 ARZXY2_RS14575 b65862323becc03e73b078ce9986eab6 146 SUPERFAMILY SSF101116 11 124 4.58E-27 T 09-03-2017 IPR003713 Flagellar protein FliS GO:0044780 ARZXY2_RS00920 f3137649f747f1b95aeef784a25e8424 383 Gene3D G3DSA:1.10.3290.10 43 294 4.3E-45 T 09-03-2017 IPR003812 Fido domain ARZXY2_RS00920 f3137649f747f1b95aeef784a25e8424 383 Pfam PF02661 Fic/DOC family 127 224 7.7E-21 T 09-03-2017 IPR003812 Fido domain ARZXY2_RS00920 f3137649f747f1b95aeef784a25e8424 383 SUPERFAMILY SSF140931 108 287 9.81E-34 T 09-03-2017 IPR003812 Fido domain ARZXY2_RS14760 81c013aeb3a7b1df4305f071bcd4bc11 500 SUPERFAMILY SSF53756 30 494 1.76E-142 T 09-03-2017 ARZXY2_RS14760 81c013aeb3a7b1df4305f071bcd4bc11 500 Pfam PF00982 Glycosyltransferase family 20 30 492 1.7E-146 T 09-03-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 ARZXY2_RS14760 81c013aeb3a7b1df4305f071bcd4bc11 500 Gene3D G3DSA:3.40.50.2000 30 278 7.5E-84 T 09-03-2017 ARZXY2_RS14760 81c013aeb3a7b1df4305f071bcd4bc11 500 Gene3D G3DSA:3.40.50.2000 279 476 5.3E-71 T 09-03-2017 ARZXY2_RS01970 c9a59bf6cfadc59ec8355371becc6952 328 SUPERFAMILY SSF51735 1 295 2.55E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01970 c9a59bf6cfadc59ec8355371becc6952 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 1.5E-27 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS01970 c9a59bf6cfadc59ec8355371becc6952 328 Gene3D G3DSA:3.40.50.720 2 295 1.3E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS07950 6b311be44040c6744cb4b8de9cfdeb6b 243 SUPERFAMILY SSF52317 26 213 6.04E-19 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07950 6b311be44040c6744cb4b8de9cfdeb6b 243 Gene3D G3DSA:3.40.50.880 34 215 1.3E-12 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07950 6b311be44040c6744cb4b8de9cfdeb6b 243 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 11 202 2.1E-35 T 09-03-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 ARZXY2_RS19705 6898e7e67931e1d67d59d2fae2e2feb8 114 SMART SM00530 22 77 1.2E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS19705 6898e7e67931e1d67d59d2fae2e2feb8 114 Gene3D G3DSA:1.10.260.40 19 76 8.3E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS19705 6898e7e67931e1d67d59d2fae2e2feb8 114 Pfam PF13560 Helix-turn-helix domain 19 73 8.1E-9 T 09-03-2017 ARZXY2_RS19705 6898e7e67931e1d67d59d2fae2e2feb8 114 SUPERFAMILY SSF47413 13 74 4.5E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS01990 00c2c233d88b7d278e245662614b2a10 370 SUPERFAMILY SSF55920 144 353 1.7E-20 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS01990 00c2c233d88b7d278e245662614b2a10 370 Pfam PF00557 Metallopeptidase family M24 156 342 3.3E-7 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS01990 00c2c233d88b7d278e245662614b2a10 370 Gene3D G3DSA:3.90.230.10 144 349 1.2E-10 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS09275 20294c60cd2e6323b55a5e419ab98ca7 221 Pfam PF01738 Dienelactone hydrolase family 79 203 2.8E-5 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 ARZXY2_RS09275 20294c60cd2e6323b55a5e419ab98ca7 221 Gene3D G3DSA:3.40.50.1820 27 206 1.3E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS09275 20294c60cd2e6323b55a5e419ab98ca7 221 SUPERFAMILY SSF53474 2 206 9.04E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS15285 54dac17d12695691d1f7e936e7234f49 397 SUPERFAMILY SSF51445 2 113 2.79E-8 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS15285 54dac17d12695691d1f7e936e7234f49 397 SUPERFAMILY SSF51445 249 379 2.79E-8 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS15285 54dac17d12695691d1f7e936e7234f49 397 SUPERFAMILY SSF51445 174 216 2.79E-8 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily ARZXY2_RS15285 54dac17d12695691d1f7e936e7234f49 397 Gene3D G3DSA:3.20.20.80 2 337 9.3E-10 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 ARZXY2_RS17275 5e72c8e4ef34326b926847fd03677135 88 Gene3D G3DSA:1.10.720.30 55 88 3.0E-4 T 09-03-2017 IPR003034 SAP domain ARZXY2_RS17275 5e72c8e4ef34326b926847fd03677135 88 Pfam PF07498 Rho termination factor, N-terminal domain 57 83 1.8E-5 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 ARZXY2_RS05740 2c66957e221173ae2449afdd3401547a 178 SUPERFAMILY SSF160379 1 174 1.27E-44 T 09-03-2017 ARZXY2_RS05740 2c66957e221173ae2449afdd3401547a 178 Gene3D G3DSA:3.30.70.1280 1 86 7.4E-28 T 09-03-2017 ARZXY2_RS05740 2c66957e221173ae2449afdd3401547a 178 Pfam PF08002 Protein of unknown function (DUF1697) 1 117 3.2E-35 T 09-03-2017 IPR012545 Protein of unknown function DUF1697 ARZXY2_RS05740 2c66957e221173ae2449afdd3401547a 178 PIRSF PIRSF008502 1 177 1.1E-39 T 09-03-2017 IPR012545 Protein of unknown function DUF1697 ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 Pfam PF12796 Ankyrin repeats (3 copies) 110 204 8.2E-12 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 SMART SM00248 135 164 18.0 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 SMART SM00248 69 98 510.0 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 SMART SM00248 102 131 1900.0 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 SMART SM00248 168 202 3.3 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 SUPERFAMILY SSF48403 74 228 2.64E-35 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS16535 2d43e8d4c975175cee61aad3566b8534 229 Gene3D G3DSA:1.25.40.20 74 228 8.9E-35 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 PRINTS PR00990 Ribokinase signature 30 49 6.5E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 PRINTS PR00990 Ribokinase signature 191 206 6.5E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 PRINTS PR00990 Ribokinase signature 230 241 6.5E-6 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 Pfam PF00294 pfkB family carbohydrate kinase 4 307 4.8E-45 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 4 314 1.5E-106 T 09-03-2017 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 Gene3D G3DSA:3.40.1190.20 4 318 7.1E-88 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS14090 cd00b563544ff0abaf3e0ec073c08025 335 SUPERFAMILY SSF53613 3 315 5.14E-69 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS07865 47b8c40b2639c6a9a6d965a2ef20473d 252 Gene3D G3DSA:3.90.1550.10 15 239 2.3E-43 T 09-03-2017 ARZXY2_RS07865 47b8c40b2639c6a9a6d965a2ef20473d 252 SUPERFAMILY SSF55681 16 240 2.68E-41 T 09-03-2017 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 ProSitePatterns PS00356 LacI-type HTH domain signature. 44 62 - T 09-03-2017 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 SUPERFAMILY SSF46689 9 79 1.59E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 SUPERFAMILY SSF53697 108 287 7.89E-36 T 09-03-2017 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 Pfam PF01380 SIS domain 143 270 1.8E-15 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 Gene3D G3DSA:3.40.50.10490 122 279 1.5E-32 T 09-03-2017 ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 Gene3D G3DSA:1.10.10.10 9 80 6.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS00770 1552839412abdc65b7c42ac096f6cfe0 301 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 79 2.7E-13 T 09-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 ARZXY2_RS11450 b16cd1581c86a216c68e09a04f1bfef5 151 Pfam PF02391 MoaE protein 15 129 1.9E-32 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11450 b16cd1581c86a216c68e09a04f1bfef5 151 SUPERFAMILY SSF54690 14 149 2.88E-38 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS11450 b16cd1581c86a216c68e09a04f1bfef5 151 Gene3D G3DSA:3.90.1170.40 10 148 2.5E-44 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 ARZXY2_RS01615 142f163bf7487c118992107ba3a57224 415 Pfam PF13478 XdhC Rossmann domain 229 375 2.8E-38 T 09-03-2017 IPR027051 XdhC Rossmann domain ARZXY2_RS01615 142f163bf7487c118992107ba3a57224 415 Pfam PF02625 XdhC and CoxI family 16 80 2.5E-20 T 09-03-2017 IPR003777 XdhC- CoxI ARZXY2_RS01615 142f163bf7487c118992107ba3a57224 415 Gene3D G3DSA:3.40.50.720 225 277 1.8E-4 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS22120 1627533ad4b924c0c7c012f273f76809 135 Gene3D G3DSA:3.40.50.300 48 116 1.2E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS22120 1627533ad4b924c0c7c012f273f76809 135 SUPERFAMILY SSF52540 42 116 1.1E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS22120 1627533ad4b924c0c7c012f273f76809 135 Pfam PF00005 ABC transporter 67 118 7.5E-12 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS15150 0eeb5e20c0ea73e12bfc7cb7b3441275 271 Pfam PF00005 ABC transporter 39 190 5.8E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS15150 0eeb5e20c0ea73e12bfc7cb7b3441275 271 SMART SM00382 47 239 2.3E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS15150 0eeb5e20c0ea73e12bfc7cb7b3441275 271 SUPERFAMILY SSF52540 13 261 1.04E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS15150 0eeb5e20c0ea73e12bfc7cb7b3441275 271 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS15150 0eeb5e20c0ea73e12bfc7cb7b3441275 271 Gene3D G3DSA:3.40.50.300 11 263 1.4E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS20555 fa50596a46f00602d8f025a34ecdbd0c 298 Pfam PF13835 Domain of unknown function (DUF4194) 69 231 3.6E-30 T 09-03-2017 IPR025449 Protein of unknown function DUF4194 ARZXY2_RS17895 5effa72a7fd05e5b14587e3301a07c0b 297 Pfam PF13560 Helix-turn-helix domain 32 86 2.4E-13 T 09-03-2017 ARZXY2_RS17895 5effa72a7fd05e5b14587e3301a07c0b 297 SMART SM00530 6 83 6.0E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS17895 5effa72a7fd05e5b14587e3301a07c0b 297 SUPERFAMILY SSF47413 32 81 5.04E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS17895 5effa72a7fd05e5b14587e3301a07c0b 297 Gene3D G3DSA:1.10.260.40 5 82 9.7E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS10465 6d1d4551bde94e85bbdbe1cae98792a4 359 Gene3D G3DSA:3.40.640.10 12 264 4.4E-57 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS10465 6d1d4551bde94e85bbdbe1cae98792a4 359 Pfam PF01212 Beta-eliminating lyase 21 305 3.4E-53 T 09-03-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 ARZXY2_RS10465 6d1d4551bde94e85bbdbe1cae98792a4 359 SUPERFAMILY SSF53383 19 354 1.13E-88 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS10465 6d1d4551bde94e85bbdbe1cae98792a4 359 Gene3D G3DSA:3.90.1150.10 268 354 2.3E-27 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS14370 45e10f33a270e384829226817f330303 303 SUPERFAMILY SSF47090 56 108 1.12E-8 T 09-03-2017 IPR002477 Peptidoglycan binding-like ARZXY2_RS14370 45e10f33a270e384829226817f330303 303 Pfam PF01471 Putative peptidoglycan binding domain 65 107 7.7E-7 T 09-03-2017 IPR002477 Peptidoglycan binding-like ARZXY2_RS14370 45e10f33a270e384829226817f330303 303 Gene3D G3DSA:1.10.101.10 58 108 3.5E-10 T 09-03-2017 IPR002477 Peptidoglycan binding-like ARZXY2_RS07470 b6171f91d948fbe1bd92c989578bb10a 266 Pfam PF07510 Protein of unknown function (DUF1524) 114 250 2.7E-15 T 09-03-2017 IPR011089 Domain of unknown function DUF1524 ARZXY2_RS08470 621ac0ba712050c31dc5b54e527904b1 353 SUPERFAMILY SSF48179 173 323 6.46E-26 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 ARZXY2_RS08470 621ac0ba712050c31dc5b54e527904b1 353 Gene3D G3DSA:1.10.1040.10 177 319 2.0E-28 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 ARZXY2_RS08470 621ac0ba712050c31dc5b54e527904b1 353 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 172 310 3.2E-28 T 09-03-2017 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 ARZXY2_RS02830 dd02890b2854aa81de8fe1543d2668db 140 SUPERFAMILY SSF160631 4 133 3.92E-6 T 09-03-2017 ARZXY2_RS02830 dd02890b2854aa81de8fe1543d2668db 140 SMART SM00860 26 130 8.5E-4 T 09-03-2017 IPR018958 SMI1/KNR4-like domain ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 129 152 - T 09-03-2017 IPR025505 FHIPEP conserved site ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PIRSF PIRSF005419 1 680 7.6E-239 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 25 38 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 62 81 5.2E-54 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS14435 3cdaad58729008f9fa03ca01dec54fb0 682 Pfam PF00771 FHIPEP family 18 663 2.0E-236 T 09-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 ARZXY2_RS04745 35ff78b2412b8c3abcbfc938abb21b00 324 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 163 277 5.5E-8 T 09-03-2017 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 Gene3D G3DSA:3.40.50.720 1 139 4.2E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 Gene3D G3DSA:3.30.360.10 140 366 9.2E-36 T 09-03-2017 ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 SUPERFAMILY SSF55347 129 303 1.54E-26 T 09-03-2017 ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 218 2.9E-11 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 SUPERFAMILY SSF51735 3 152 2.1E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12310 82fe3744134765465ca608b814b5c57c 400 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 1.3E-15 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS06240 cb68c37a14e87a9766ec0729deab51c5 163 PIRSF PIRSF002070 1 158 8.5E-18 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS06240 cb68c37a14e87a9766ec0729deab51c5 163 Gene3D G3DSA:2.40.50.140 6 162 6.5E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS06240 cb68c37a14e87a9766ec0729deab51c5 163 Pfam PF00436 Single-strand binding protein family 6 108 5.0E-10 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 ARZXY2_RS06240 cb68c37a14e87a9766ec0729deab51c5 163 SUPERFAMILY SSF50249 6 162 1.54E-19 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 270 284 - T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 Pfam PF05199 GMC oxidoreductase 383 522 1.6E-39 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 Gene3D G3DSA:3.50.50.60 463 529 7.0E-106 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 Gene3D G3DSA:3.50.50.60 200 329 7.0E-106 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 Gene3D G3DSA:3.50.50.60 12 135 7.0E-106 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 SUPERFAMILY SSF54373 306 470 3.34E-47 T 09-03-2017 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 SUPERFAMILY SSF51905 12 304 1.68E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 SUPERFAMILY SSF51905 469 530 1.68E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15000 4ba0d931abbec94ac00dab581358cd4d 550 Pfam PF00732 GMC oxidoreductase 14 312 5.3E-72 T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 Gene3D G3DSA:2.40.10.10 269 378 5.2E-14 T 09-03-2017 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 Pfam PF13365 Trypsin-like peptidase domain 216 352 1.8E-22 T 09-03-2017 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 Gene3D G3DSA:2.40.10.10 185 268 1.1E-17 T 09-03-2017 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 SUPERFAMILY SSF50494 191 378 6.29E-35 T 09-03-2017 IPR009003 Peptidase S1, PA clan ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 Pfam PF02674 Colicin V production protein 7 149 4.8E-19 T 09-03-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 2.9E-8 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 PRINTS PR00834 HtrA/DegQ protease family signature 224 236 2.9E-8 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 PRINTS PR00834 HtrA/DegQ protease family signature 345 362 2.9E-8 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS01735 e2148bbb6706d35c31904284739acde8 394 PRINTS PR00834 HtrA/DegQ protease family signature 323 340 2.9E-8 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 ARZXY2_RS09350 48f153115b020b3c93eafda3893c7736 414 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 263 2.6E-68 T 09-03-2017 IPR014145 DNA ligase D, polymerase domain ARZXY2_RS17795 8b7b7dae4020c43c5f4b0376da6492ef 86 Pfam PF14019 Protein of unknown function (DUF4235) 5 80 1.3E-21 T 09-03-2017 IPR025329 Protein of unknown function DUF4235 ARZXY2_RS09110 76ec7043b68980dd1c49f6c4361614f8 238 SUPERFAMILY SSF56784 8 220 4.14E-43 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09110 76ec7043b68980dd1c49f6c4361614f8 238 Gene3D G3DSA:3.40.50.1000 78 217 3.5E-33 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS09110 76ec7043b68980dd1c49f6c4361614f8 238 Gene3D G3DSA:1.10.150.240 20 77 1.0E-15 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 ARZXY2_RS09110 76ec7043b68980dd1c49f6c4361614f8 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 189 3.6E-20 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS08115 502e0c88d41b49c576dc3644f2014c82 194 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 11 187 33.666 T 09-03-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 ARZXY2_RS08115 502e0c88d41b49c576dc3644f2014c82 194 Pfam PF00156 Phosphoribosyl transferase domain 15 156 6.9E-21 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 ARZXY2_RS08115 502e0c88d41b49c576dc3644f2014c82 194 SUPERFAMILY SSF53271 12 179 6.95E-38 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS08115 502e0c88d41b49c576dc3644f2014c82 194 Gene3D G3DSA:3.40.50.2020 12 176 5.6E-44 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like ARZXY2_RS12660 15794def5423ac6213a67df12bd78681 448 Pfam PF01734 Patatin-like phospholipase 5 171 2.3E-16 T 09-03-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 ARZXY2_RS12660 15794def5423ac6213a67df12bd78681 448 SUPERFAMILY SSF52151 1 211 4.19E-23 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ARZXY2_RS20290 fc82f7a9f4c3875d77bea4ac959d6125 427 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 281 341 1.4E-7 T 09-03-2017 ARZXY2_RS20290 fc82f7a9f4c3875d77bea4ac959d6125 427 Gene3D G3DSA:2.130.10.130 92 403 2.8E-14 T 09-03-2017 ARZXY2_RS20290 fc82f7a9f4c3875d77bea4ac959d6125 427 SUPERFAMILY SSF69318 173 420 6.67E-28 T 09-03-2017 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 SUPERFAMILY SSF52402 150 267 2.26E-17 T 09-03-2017 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 Pfam PF00582 Universal stress protein family 7 140 4.9E-12 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 Pfam PF00582 Universal stress protein family 227 267 1.8E-5 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 Pfam PF00582 Universal stress protein family 150 195 7.2E-8 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 SUPERFAMILY SSF52402 8 142 3.35E-18 T 09-03-2017 ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 PRINTS PR01438 Universal stress protein signature 231 243 1.0E-9 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 PRINTS PR01438 Universal stress protein signature 147 165 1.0E-9 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 PRINTS PR01438 Universal stress protein signature 248 269 1.0E-9 T 09-03-2017 IPR006015 Universal stress protein A ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 Gene3D G3DSA:3.40.50.620 5 133 1.3E-17 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS09805 26291fdb03bf15756e939f0493814bc0 269 Gene3D G3DSA:3.40.50.620 134 266 1.5E-23 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS03365 8e0b2ce80c284213bc50bb8a6de39397 82 Pfam PF04024 PspC domain 18 66 1.3E-15 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 191 210 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 153 172 5.5E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 SUPERFAMILY SSF51569 2 325 3.22E-132 T 09-03-2017 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 SMART SM01004 3 323 2.7E-215 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 PIRSF PIRSF001415 1 326 1.4E-144 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 09-03-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 Gene3D G3DSA:3.20.20.70 2 325 2.8E-143 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS04490 18aea797be358c719beb50d0bbb0f226 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 322 1.4E-138 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 ARZXY2_RS00745 cb4acab2e7f72c086ac53bc25735deaa 266 Gene3D G3DSA:3.40.50.2300 79 252 2.7E-42 T 09-03-2017 ARZXY2_RS00745 cb4acab2e7f72c086ac53bc25735deaa 266 SUPERFAMILY SSF53822 2 252 1.04E-58 T 09-03-2017 IPR028082 Periplasmic binding protein-like I ARZXY2_RS00745 cb4acab2e7f72c086ac53bc25735deaa 266 Gene3D G3DSA:3.40.50.2300 1 78 3.1E-18 T 09-03-2017 ARZXY2_RS00745 cb4acab2e7f72c086ac53bc25735deaa 266 Pfam PF13407 Periplasmic binding protein domain 3 226 1.7E-46 T 09-03-2017 IPR025997 Periplasmic binding protein ARZXY2_RS00190 78caba3cb7b85e467740331f2b315538 192 Gene3D G3DSA:1.10.260.40 3 64 1.0E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00190 78caba3cb7b85e467740331f2b315538 192 Pfam PF01381 Helix-turn-helix 12 64 2.9E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS00190 78caba3cb7b85e467740331f2b315538 192 SUPERFAMILY SSF47413 4 64 1.5E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS00190 78caba3cb7b85e467740331f2b315538 192 SMART SM00530 11 66 1.0E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS09510 18e8708f7b412a86ce304697a4a9d853 165 SUPERFAMILY SSF48498 48 135 2.05E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 168 371 8.6E-41 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 Pfam PF13241 Putative NAD(P)-binding 11 117 4.9E-22 T 09-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 SUPERFAMILY SSF53790 165 394 4.45E-66 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 Gene3D G3DSA:3.40.50.720 6 112 5.5E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 Gene3D G3DSA:3.30.950.10 282 395 1.1E-36 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 SUPERFAMILY SSF51735 6 110 3.15E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 149 2.0E-24 T 09-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 Gene3D G3DSA:3.40.1010.10 165 281 4.4E-38 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 ARZXY2_RS02915 faa258215f00ac485b6998737c52011f 420 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 166 394 3.0E-79 T 09-03-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 ARZXY2_RS16275 b8bff2c6648dc2e913afd68fce98dc75 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 267 31.863 T 09-03-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 ARZXY2_RS16275 b8bff2c6648dc2e913afd68fce98dc75 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 28 273 1.3E-73 T 09-03-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 ARZXY2_RS16275 b8bff2c6648dc2e913afd68fce98dc75 273 Gene3D G3DSA:3.40.50.620 5 272 2.2E-78 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS16275 b8bff2c6648dc2e913afd68fce98dc75 273 Pfam PF02540 NAD synthase 24 264 2.5E-70 T 09-03-2017 IPR022310 NAD/GMP synthase ARZXY2_RS16275 b8bff2c6648dc2e913afd68fce98dc75 273 SUPERFAMILY SSF52402 4 272 2.71E-83 T 09-03-2017 ARZXY2_RS17360 b5a0b98c0b8bbc1480de0b18462ebf46 171 SUPERFAMILY SSF55729 1 135 2.92E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17360 b5a0b98c0b8bbc1480de0b18462ebf46 171 Gene3D G3DSA:3.40.630.30 1 135 5.4E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17360 b5a0b98c0b8bbc1480de0b18462ebf46 171 Pfam PF00583 Acetyltransferase (GNAT) family 62 132 5.0E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 Gene3D G3DSA:3.40.50.720 7 212 4.3E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.9E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.9E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.9E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 SUPERFAMILY SSF51735 5 215 2.9E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17785 e8b15f83d404e013422e9d1c19e8ee2f 265 Pfam PF00106 short chain dehydrogenase 9 194 5.6E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09720 b15e82f3a9f3bba4b4a3e8726678399e 588 SUPERFAMILY SSF52016 380 565 7.85E-55 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel ARZXY2_RS09720 b15e82f3a9f3bba4b4a3e8726678399e 588 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS09720 b15e82f3a9f3bba4b4a3e8726678399e 588 SUPERFAMILY SSF143975 8 379 2.35E-116 T 09-03-2017 ARZXY2_RS09720 b15e82f3a9f3bba4b4a3e8726678399e 588 Pfam PF00920 Dehydratase family 45 560 1.4E-174 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 ARZXY2_RS03380 e91ad23c5bfe053eee443f25abe35078 477 SUPERFAMILY SSF103473 134 269 6.93E-5 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS03380 e91ad23c5bfe053eee443f25abe35078 477 SUPERFAMILY SSF55874 343 462 2.1E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS03380 e91ad23c5bfe053eee443f25abe35078 477 Pfam PF04024 PspC domain 10 64 8.3E-14 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal ARZXY2_RS03380 e91ad23c5bfe053eee443f25abe35078 477 Gene3D G3DSA:3.30.565.10 370 465 3.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS03380 e91ad23c5bfe053eee443f25abe35078 477 Gene3D G3DSA:3.30.565.10 294 314 3.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11055 6f1393fd93bdf54b9bed325b537047d6 299 Gene3D G3DSA:3.40.50.300 45 295 1.3E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11055 6f1393fd93bdf54b9bed325b537047d6 299 Pfam PF13614 AAA domain 45 221 5.1E-63 T 09-03-2017 IPR025669 AAA domain ARZXY2_RS11055 6f1393fd93bdf54b9bed325b537047d6 299 SUPERFAMILY SSF52540 44 295 1.21E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18585 21fc96add1464ab6a4a2c8dbbda914d0 323 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 263 1.3E-59 T 09-03-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal ARZXY2_RS18585 21fc96add1464ab6a4a2c8dbbda914d0 323 Pfam PF02096 60Kd inner membrane protein 39 263 1.4E-54 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 ARZXY2_RS19980 e78a3610048874f5324694f284f509fc 218 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 195 5.6E-40 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS19980 e78a3610048874f5324694f284f509fc 218 Gene3D G3DSA:3.40.50.1240 1 198 7.4E-36 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS19980 e78a3610048874f5324694f284f509fc 218 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 ARZXY2_RS19980 e78a3610048874f5324694f284f509fc 218 SMART SM00855 2 156 3.3E-20 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 ARZXY2_RS19980 e78a3610048874f5324694f284f509fc 218 SUPERFAMILY SSF53254 1 200 2.14E-38 T 09-03-2017 IPR029033 Histidine phosphatase superfamily ARZXY2_RS08785 cbf3af08ea36073bc215c49b69ee7461 559 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 103 559 4.4E-124 T 09-03-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase ARZXY2_RS08785 cbf3af08ea36073bc215c49b69ee7461 559 Pfam PF02397 Bacterial sugar transferase 366 553 8.6E-58 T 09-03-2017 IPR003362 Bacterial sugar transferase ARZXY2_RS04525 92263afc93dfaad314c1053dc942ef38 236 SMART SM00479 8 183 1.1E-19 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS04525 92263afc93dfaad314c1053dc942ef38 236 Gene3D G3DSA:3.30.420.10 7 185 6.0E-34 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS04525 92263afc93dfaad314c1053dc942ef38 236 Pfam PF00929 Exonuclease 11 174 5.8E-12 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III ARZXY2_RS04525 92263afc93dfaad314c1053dc942ef38 236 SUPERFAMILY SSF53098 5 186 2.89E-41 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 SUPERFAMILY SSF51556 81 387 5.79E-57 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 Pfam PF01979 Amidohydrolase family 77 413 3.9E-29 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 Gene3D G3DSA:3.20.20.140 83 383 6.4E-60 T 09-03-2017 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 SUPERFAMILY SSF51338 27 81 2.33E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 SUPERFAMILY SSF51338 387 415 2.33E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 Gene3D G3DSA:2.30.40.10 387 423 4.0E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS09650 eae4dce1adf686a0190dd7b74e0d90ae 426 Gene3D G3DSA:2.30.40.10 25 82 4.0E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 75 5.7E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 Gene3D G3DSA:1.10.357.10 75 195 2.3E-11 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 SUPERFAMILY SSF46689 21 93 4.68E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 Gene3D G3DSA:1.10.10.60 21 73 5.0E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 2.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS12510 50746379b7346af533493a0e6c78e727 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 2.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 SUPERFAMILY SSF52540 29 252 1.51E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Gene3D G3DSA:1.10.3710.10 397 486 9.8E-30 T 09-03-2017 ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Pfam PF16193 AAA C-terminal domain 215 316 7.2E-25 T 09-03-2017 IPR032423 AAA ATPase, C-terminal domain ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Gene3D G3DSA:3.40.50.300 32 185 5.0E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Gene3D G3DSA:1.10.8.60 193 245 2.3E-9 T 09-03-2017 ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 SMART SM00382 76 193 1.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Pfam PF12002 MgsA AAA+ ATPase C terminal 317 482 6.1E-72 T 09-03-2017 IPR021886 MgsA AAA+ ATPase C-terminal ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 38 166 2.0E-14 T 09-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 SUPERFAMILY SSF48019 302 486 4.76E-76 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 ARZXY2_RS08040 6fd284de7bce26f76972b2c0f7e01844 489 Gene3D G3DSA:1.20.272.10 298 396 9.6E-46 T 09-03-2017 ARZXY2_RS19890 4e104b1322fb5bc9ca22a0c6c6ed4132 92 Pfam PF04226 Transglycosylase associated protein 34 83 1.8E-7 T 09-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 ARZXY2_RS17810 79362b4d16b3e88601121cdc4b077c53 217 SUPERFAMILY SSF101473 5 206 1.03E-52 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS17810 79362b4d16b3e88601121cdc4b077c53 217 SMART SM01120 32 206 6.4E-74 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS17810 79362b4d16b3e88601121cdc4b077c53 217 Pfam PF02734 DAK2 domain 32 205 5.4E-53 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 ARZXY2_RS17810 79362b4d16b3e88601121cdc4b077c53 217 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 204 2.9E-71 T 09-03-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 ARZXY2_RS17415 fe2bba319750396805c1845e9b96fd1c 118 SUPERFAMILY SSF55729 17 101 2.23E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17415 fe2bba319750396805c1845e9b96fd1c 118 Pfam PF14542 GCN5-related N-acetyl-transferase 26 101 1.8E-22 T 09-03-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase ARZXY2_RS17415 fe2bba319750396805c1845e9b96fd1c 118 Gene3D G3DSA:3.40.630.30 19 101 7.8E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS03220 15ea4d7ae69ccef585b7b11397b5d4d2 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 295 4.9E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03220 15ea4d7ae69ccef585b7b11397b5d4d2 304 Gene3D G3DSA:1.10.3720.10 80 296 2.2E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03220 15ea4d7ae69ccef585b7b11397b5d4d2 304 SUPERFAMILY SSF161098 101 283 2.88E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS14560 63b6798a70ef5ce96787494116e44368 213 Pfam PF04961 Formiminotransferase-cyclodeaminase 13 163 3.3E-22 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 ARZXY2_RS14560 63b6798a70ef5ce96787494116e44368 213 SUPERFAMILY SSF101262 11 166 9.15E-22 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 ARZXY2_RS19670 49adab2dad751aec35eb09c6ad636669 289 SUPERFAMILY SSF52200 86 179 2.49E-11 T 09-03-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 ARZXY2_RS19670 49adab2dad751aec35eb09c6ad636669 289 Pfam PF13676 TIR domain 87 186 2.5E-14 T 09-03-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 ARZXY2_RS19670 49adab2dad751aec35eb09c6ad636669 289 Gene3D G3DSA:3.40.50.10140 87 161 4.9E-6 T 09-03-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 Hamap MF_01403 Probable phosphoketolase. 11 793 41.771 T 09-03-2017 IPR023962 Probable phosphoketolase ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 ProSitePatterns PS60003 Phosphoketolase signature 2. 163 181 - T 09-03-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 405 579 1.4E-90 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 SUPERFAMILY SSF52518 10 374 6.33E-74 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 Pfam PF09363 XFP C-terminal domain 590 791 6.2E-95 T 09-03-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 SUPERFAMILY SSF52518 382 592 8.83E-25 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 ProSitePatterns PS60002 Phosphoketolase signature 1. 150 156 - T 09-03-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 PIRSF PIRSF017245 1 793 0.0 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 Gene3D G3DSA:3.40.50.970 23 372 6.7E-20 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS06105 cdc6a55d44b2e27eef99c3bf8f3a8fbf 810 Pfam PF09364 XFP N-terminal domain 15 390 1.6E-191 T 09-03-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 Pfam PF00551 Formyl transferase 110 286 3.9E-38 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 29 304 2.6E-96 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 25 304 43.47 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 SUPERFAMILY SSF55021 27 105 1.12E-16 T 09-03-2017 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 SUPERFAMILY SSF53328 110 304 9.68E-62 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PIRSF PIRSF036480 25 305 3.4E-104 T 09-03-2017 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 Gene3D G3DSA:3.30.70.260 25 104 1.0E-20 T 09-03-2017 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 30 56 2.0E-43 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 132 2.0E-43 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 278 2.0E-43 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 278 303 2.0E-43 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 132 159 2.0E-43 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 ARZXY2_RS16450 ebd5807d1adec89ef92b64b069e4e790 305 Gene3D G3DSA:3.40.50.170 110 304 3.3E-57 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 Gene3D G3DSA:3.90.79.10 150 320 1.8E-41 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 ProSitePatterns PS00893 Nudix box signature. 221 242 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 SUPERFAMILY SSF55811 139 321 1.07E-41 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 154 185 3.9E-12 T 09-03-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 PRINTS PR00502 NUDIX hydrolase family signature 216 230 9.6E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 PRINTS PR00502 NUDIX hydrolase family signature 230 245 9.6E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 ARZXY2_RS04550 36f40c847a0de1baaf4288430849ac6a 328 Pfam PF00293 NUDIX domain 190 295 2.0E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 ARZXY2_RS05865 e0321999a2bd315c8696afd8c9b05638 1161 Gene3D G3DSA:3.40.50.300 204 308 5.7E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05865 e0321999a2bd315c8696afd8c9b05638 1161 Gene3D G3DSA:3.40.50.300 55 87 5.7E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05865 e0321999a2bd315c8696afd8c9b05638 1161 SUPERFAMILY SSF52540 30 94 2.11E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05865 e0321999a2bd315c8696afd8c9b05638 1161 SUPERFAMILY SSF52540 224 306 2.11E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17685 50f49be64f4a69f1b5afe3bab581df5d 140 SUPERFAMILY SSF52788 8 132 1.57E-35 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS17685 50f49be64f4a69f1b5afe3bab581df5d 140 SMART SM00226 9 134 2.2E-44 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS17685 50f49be64f4a69f1b5afe3bab581df5d 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 11 131 2.0E-23 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily ARZXY2_RS17685 50f49be64f4a69f1b5afe3bab581df5d 140 Gene3D G3DSA:3.40.50.270 7 132 6.8E-40 T 09-03-2017 ARZXY2_RS07445 7938f338a0eea4323a8d18f7de7e4e50 245 Pfam PF02591 C4-type zinc ribbon domain 205 238 1.4E-8 T 09-03-2017 IPR003743 C4-type zinc ribbon domain ARZXY2_RS18515 4463ddf672b42706451296fabb62a6a3 302 Pfam PF00892 EamA-like transporter family 148 282 1.4E-13 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18515 4463ddf672b42706451296fabb62a6a3 302 Pfam PF00892 EamA-like transporter family 23 135 1.6E-6 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 ARZXY2_RS18515 4463ddf672b42706451296fabb62a6a3 302 SUPERFAMILY SSF103481 37 137 1.12E-7 T 09-03-2017 ARZXY2_RS18515 4463ddf672b42706451296fabb62a6a3 302 SUPERFAMILY SSF103481 188 287 3.53E-11 T 09-03-2017 ARZXY2_RS09980 4e70b27f36628b47c93a49d92c8ec42b 154 Pfam PF12724 Flavodoxin domain 5 65 1.6E-7 T 09-03-2017 IPR026816 Flavodoxin domain ARZXY2_RS09980 4e70b27f36628b47c93a49d92c8ec42b 154 Gene3D G3DSA:3.40.50.360 1 150 3.4E-23 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS09980 4e70b27f36628b47c93a49d92c8ec42b 154 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 09-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 ARZXY2_RS09980 4e70b27f36628b47c93a49d92c8ec42b 154 SUPERFAMILY SSF52218 1 148 2.33E-17 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 SUPERFAMILY SSF56784 13 240 2.47E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 Gene3D G3DSA:3.40.50.1000 103 240 7.1E-34 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 102 213 8.3E-13 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 12 211 9.6E-47 T 09-03-2017 IPR010976 Beta-phosphoglucomutase hydrolase ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 209 6.1E-16 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS17175 b9e1985555f22d2097496f3e9ace79c5 241 Gene3D G3DSA:1.10.150.240 25 102 4.3E-7 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 ARZXY2_RS18210 6b2a8c7baa4d9680f4f18cc5db593b47 451 Pfam PF00860 Permease family 36 387 9.1E-81 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS18210 6b2a8c7baa4d9680f4f18cc5db593b47 451 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 32 406 2.7E-97 T 09-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 Pfam PF00501 AMP-binding enzyme 104 359 8.8E-35 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 ProSitePatterns PS00455 Putative AMP-binding domain signature. 112 123 - T 09-03-2017 IPR020845 AMP-binding, conserved site ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 Gene3D G3DSA:2.30.38.10 280 352 5.9E-15 T 09-03-2017 ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 Pfam PF13193 AMP-binding enzyme C-terminal domain 368 442 2.1E-7 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 Gene3D G3DSA:3.40.50.980 106 265 3.4E-25 T 09-03-2017 ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 Gene3D G3DSA:3.30.300.30 355 449 8.0E-20 T 09-03-2017 ARZXY2_RS08970 424ba949af0fddd3e7a8ea53a44cca60 463 SUPERFAMILY SSF56801 4 455 2.88E-83 T 09-03-2017 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 2.1E-40 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 SUPERFAMILY SSF64518 1 278 2.09E-84 T 09-03-2017 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 PRINTS PR00207 Flagellin signature 37 54 1.0E-22 T 09-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 PRINTS PR00207 Flagellin signature 76 95 1.0E-22 T 09-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 PRINTS PR00207 Flagellin signature 111 134 1.0E-22 T 09-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 Pfam PF00700 Bacterial flagellin C-terminal helical region 192 277 1.8E-27 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS14585 4bacce9d97f149dac51bc3976841bd21 278 Gene3D G3DSA:1.20.1330.10 54 234 1.3E-51 T 09-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 ARZXY2_RS18420 3a28a3c5494d5b214c49dd5ac829375d 159 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 70 158 6.3E-15 T 09-03-2017 IPR032030 YscD, cytoplasmic domain ARZXY2_RS18420 3a28a3c5494d5b214c49dd5ac829375d 159 Gene3D G3DSA:2.60.200.20 66 158 3.7E-23 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS18420 3a28a3c5494d5b214c49dd5ac829375d 159 SUPERFAMILY SSF49879 43 157 2.32E-23 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS18420 3a28a3c5494d5b214c49dd5ac829375d 159 SMART SM00240 86 136 1.2E-9 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS01325 56a61b46eb8ea2ed05bbe9519bc1b613 272 SUPERFAMILY SSF53335 33 257 1.45E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01325 56a61b46eb8ea2ed05bbe9519bc1b613 272 Gene3D G3DSA:3.40.50.150 43 173 3.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS01325 56a61b46eb8ea2ed05bbe9519bc1b613 272 Pfam PF13649 Methyltransferase domain 59 158 8.6E-13 T 09-03-2017 ARZXY2_RS15890 30bc51ba2cefbc82c30721e24876d593 311 Gene3D G3DSA:3.40.50.720 102 283 4.4E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15890 30bc51ba2cefbc82c30721e24876d593 311 SUPERFAMILY SSF52283 24 115 1.28E-9 T 09-03-2017 ARZXY2_RS15890 30bc51ba2cefbc82c30721e24876d593 311 SUPERFAMILY SSF51735 93 283 4.8E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15890 30bc51ba2cefbc82c30721e24876d593 311 Gene3D G3DSA:3.40.50.720 33 101 1.4E-5 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15890 30bc51ba2cefbc82c30721e24876d593 311 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 99 282 1.3E-42 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 ARZXY2_RS02530 d8202754d920dbd3e34d1c3a08fba643 445 Pfam PF04932 O-Antigen ligase 204 342 1.4E-10 T 09-03-2017 IPR007016 O-antigen ligase-related ARZXY2_RS00155 80223f3b6491361523fc1b0140c18360 240 Pfam PF01988 VIT family 24 231 1.8E-54 T 09-03-2017 IPR008217 Ccc1 family ARZXY2_RS20550 4036580bc64a7bd1528dae4f8383e529 485 Pfam PF11855 Protein of unknown function (DUF3375) 21 478 7.7E-100 T 09-03-2017 IPR021804 Protein of unknown function DUF3375 ARZXY2_RS01905 3d8034c2aabe7639a5b9ec96aead0309 335 Gene3D G3DSA:3.30.420.40 1 123 1.2E-27 T 09-03-2017 ARZXY2_RS01905 3d8034c2aabe7639a5b9ec96aead0309 335 SUPERFAMILY SSF53067 130 307 9.07E-34 T 09-03-2017 ARZXY2_RS01905 3d8034c2aabe7639a5b9ec96aead0309 335 Pfam PF02541 Ppx/GppA phosphatase family 29 305 6.5E-64 T 09-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 ARZXY2_RS01905 3d8034c2aabe7639a5b9ec96aead0309 335 SUPERFAMILY SSF53067 2 125 4.7E-27 T 09-03-2017 ARZXY2_RS01905 3d8034c2aabe7639a5b9ec96aead0309 335 Gene3D G3DSA:3.30.420.150 125 306 1.4E-44 T 09-03-2017 ARZXY2_RS18260 569df8cc008382931d2c28650af743c6 380 SUPERFAMILY SSF110738 1 375 3.14E-108 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS18260 569df8cc008382931d2c28650af743c6 380 PIRSF PIRSF006078 1 380 2.8E-134 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS18260 569df8cc008382931d2c28650af743c6 380 Gene3D G3DSA:3.90.1510.10 42 276 2.5E-77 T 09-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 ARZXY2_RS18260 569df8cc008382931d2c28650af743c6 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 348 1.9E-110 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS18260 569df8cc008382931d2c28650af743c6 380 Pfam PF02595 Glycerate kinase family 3 374 3.6E-117 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 ARZXY2_RS09905 5d947616f258f463e0541d9903b11cae 334 Pfam PF00676 Dehydrogenase E1 component 19 310 2.2E-81 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 ARZXY2_RS09905 5d947616f258f463e0541d9903b11cae 334 Gene3D G3DSA:3.40.50.970 7 325 2.1E-126 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09905 5d947616f258f463e0541d9903b11cae 334 SUPERFAMILY SSF52518 7 325 2.32E-96 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS09905 5d947616f258f463e0541d9903b11cae 334 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 11 323 1.9E-131 T 09-03-2017 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 31.888 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 SUPERFAMILY SSF51735 123 280 8.2E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 2.0E-26 T 09-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.3E-54 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 SUPERFAMILY SSF53223 1 121 2.59E-26 T 09-03-2017 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 Gene3D G3DSA:3.40.192.10 8 137 2.5E-30 T 09-03-2017 ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 Gene3D G3DSA:3.40.50.720 138 263 5.3E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16465 1095c3e4f4486b0b7c7572343191b72d 300 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 6.9E-55 T 09-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 SUPERFAMILY SSF53092 16 171 6.8E-42 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 Gene3D G3DSA:3.90.230.10 172 411 3.6E-46 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 SUPERFAMILY SSF55920 172 413 1.96E-60 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 Pfam PF01321 Creatinase/Prolidase N-terminal domain 39 173 1.8E-17 T 09-03-2017 IPR000587 Creatinase, N-terminal GO:0016787 ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 Gene3D G3DSA:3.40.350.10 17 171 3.8E-47 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal ARZXY2_RS20380 9c7b34ce6b2adcad0cfc066c3e6b4c2f 418 Pfam PF00557 Metallopeptidase family M24 184 396 1.6E-25 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS00375 3e3b5d1457a83fa7d73e0fc0f58fddaa 188 Pfam PF01899 Na+/H+ ion antiporter subunit 16 165 2.8E-33 T 09-03-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 ARZXY2_RS16590 6925e974ee23b1ad631c9d3571278413 431 Pfam PF13416 Bacterial extracellular solute-binding protein 67 368 8.4E-34 T 09-03-2017 ARZXY2_RS16590 6925e974ee23b1ad631c9d3571278413 431 SUPERFAMILY SSF53850 55 426 5.43E-80 T 09-03-2017 ARZXY2_RS16590 6925e974ee23b1ad631c9d3571278413 431 Gene3D G3DSA:3.40.190.10 58 177 3.3E-18 T 09-03-2017 ARZXY2_RS16590 6925e974ee23b1ad631c9d3571278413 431 Gene3D G3DSA:3.40.190.10 178 365 2.4E-46 T 09-03-2017 ARZXY2_RS05405 27ec61602fad49cfbfa6234f512cfebd 311 Pfam PF00005 ABC transporter 21 157 1.4E-14 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS05405 27ec61602fad49cfbfa6234f512cfebd 311 SUPERFAMILY SSF52540 3 220 3.03E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05405 27ec61602fad49cfbfa6234f512cfebd 311 SMART SM00382 30 208 1.0E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS05405 27ec61602fad49cfbfa6234f512cfebd 311 Gene3D G3DSA:3.40.50.300 3 219 1.0E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 Pfam PF01037 Lrp/AsnC ligand binding domain 78 139 3.2E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 Gene3D G3DSA:3.30.70.920 57 149 1.1E-18 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 SMART SM00344 3 110 1.2E-18 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 SUPERFAMILY SSF54909 63 149 1.06E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 SUPERFAMILY SSF46785 3 63 2.72E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 Gene3D G3DSA:1.10.10.10 3 49 2.7E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05505 78a1a919880f9217d421b27b78a5fdfc 157 Pfam PF13404 AsnC-type helix-turn-helix domain 4 43 1.9E-6 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 ARZXY2_RS07625 25a519b57b788dccd963fdc59014202c 341 Gene3D G3DSA:3.60.10.10 112 336 7.0E-8 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS07625 25a519b57b788dccd963fdc59014202c 341 SUPERFAMILY SSF56219 113 337 7.72E-22 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS07625 25a519b57b788dccd963fdc59014202c 341 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 116 329 2.3E-20 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 SUPERFAMILY SSF51905 2 337 2.29E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 SUPERFAMILY SSF51905 481 521 2.29E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 Pfam PF01593 Flavin containing amine oxidoreductase 14 341 1.3E-12 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 Gene3D G3DSA:3.50.50.60 3 56 1.2E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 Gene3D G3DSA:3.50.50.60 233 309 1.2E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 Gene3D G3DSA:3.50.50.60 172 173 1.2E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17485 e797a567257f37bb1ee12fe83d66689b 534 Gene3D G3DSA:3.50.50.60 118 130 1.2E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS22860 fd7fce8211f3723e30220bbdfe0b9bd2 142 Gene3D G3DSA:3.30.420.40 2 140 9.5E-18 T 09-03-2017 ARZXY2_RS22860 fd7fce8211f3723e30220bbdfe0b9bd2 142 SUPERFAMILY SSF53067 3 140 1.1E-14 T 09-03-2017 ARZXY2_RS04300 1e752bee1930d2afab4b86d574cbdc0d 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 212 1.8E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04300 1e752bee1930d2afab4b86d574cbdc0d 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 6.0E-22 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS04300 1e752bee1930d2afab4b86d574cbdc0d 216 Gene3D G3DSA:1.10.3720.10 7 212 6.9E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04300 1e752bee1930d2afab4b86d574cbdc0d 216 SUPERFAMILY SSF161098 9 198 5.76E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05810 cb74092abacb3edb55949cd788fd4f00 413 SUPERFAMILY SSF53383 38 410 2.66E-100 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS05810 cb74092abacb3edb55949cd788fd4f00 413 Pfam PF00155 Aminotransferase class I and II 53 406 3.3E-57 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 ARZXY2_RS05810 cb74092abacb3edb55949cd788fd4f00 413 Gene3D G3DSA:3.40.640.10 66 275 3.6E-73 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS05810 cb74092abacb3edb55949cd788fd4f00 413 Gene3D G3DSA:3.90.1150.10 276 409 2.6E-20 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS15675 55a9375d58e5845ce510135b55a29f83 167 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 19 159 1.6E-20 T 09-03-2017 IPR009936 Protein of unknown function DUF1468 ARZXY2_RS02665 8f3f585f47d4ec3267d2eecde2e7cbad 397 SUPERFAMILY SSF52518 64 389 2.2E-93 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02665 8f3f585f47d4ec3267d2eecde2e7cbad 397 Gene3D G3DSA:3.40.50.970 48 384 6.2E-119 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS02665 8f3f585f47d4ec3267d2eecde2e7cbad 397 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 54 384 1.8E-127 T 09-03-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS02665 8f3f585f47d4ec3267d2eecde2e7cbad 397 Pfam PF00676 Dehydrogenase E1 component 79 346 1.4E-74 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 ARZXY2_RS05240 3550a17522a1c91b16fb6ee006288bc4 184 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 29 175 6.0E-27 T 09-03-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 ARZXY2_RS05240 3550a17522a1c91b16fb6ee006288bc4 184 SUPERFAMILY SSF81573 80 139 1.1E-12 T 09-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain ARZXY2_RS05240 3550a17522a1c91b16fb6ee006288bc4 184 Pfam PF00430 ATP synthase B/B' CF(0) 27 154 1.9E-28 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ARZXY2_RS05240 3550a17522a1c91b16fb6ee006288bc4 184 Gene3D G3DSA:1.20.5.620 80 140 1.4E-15 T 09-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain ARZXY2_RS05240 3550a17522a1c91b16fb6ee006288bc4 184 Hamap MF_01398 ATP synthase subunit b [atpF]. 18 175 12.409 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 ARZXY2_RS13495 e709cd48f535167f1fa4630625b0a18b 196 Pfam PF13835 Domain of unknown function (DUF4194) 19 178 7.7E-44 T 09-03-2017 IPR025449 Protein of unknown function DUF4194 ARZXY2_RS06885 45f5f8d393fdf281b855085880725fe7 171 Pfam PF07799 Protein of unknown function (DUF1643) 25 151 4.9E-26 T 09-03-2017 IPR012441 Protein of unknown function DUF1643 ARZXY2_RS04135 b06d794148053e0b90523c3a45d7d6c5 361 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 34 312 1.5E-95 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 ARZXY2_RS04135 b06d794148053e0b90523c3a45d7d6c5 361 Pfam PF02401 LytB protein 35 312 1.1E-87 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 ARZXY2_RS04135 b06d794148053e0b90523c3a45d7d6c5 361 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 33 316 36.382 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 ARZXY2_RS14950 57383b31d5742fbc767ddf224cdf18de 383 SUPERFAMILY SSF52540 4 209 2.55E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14950 57383b31d5742fbc767ddf224cdf18de 383 Pfam PF13177 DNA polymerase III, delta subunit 10 168 9.6E-42 T 09-03-2017 ARZXY2_RS14950 57383b31d5742fbc767ddf224cdf18de 383 Gene3D G3DSA:3.40.50.300 4 168 4.1E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12205 ae3f915e8e2e86769f7a783c2887e3fc 334 Pfam PF04657 Putative inner membrane exporter, YdcZ 19 160 1.1E-25 T 09-03-2017 IPR006750 Putative inner membrane exporter, YdcZ ARZXY2_RS12205 ae3f915e8e2e86769f7a783c2887e3fc 334 Pfam PF04657 Putative inner membrane exporter, YdcZ 180 314 1.1E-20 T 09-03-2017 IPR006750 Putative inner membrane exporter, YdcZ ARZXY2_RS17560 988dfea68ef6cf567049b5a862ab993e 292 Hamap MF_01384 Urease accessory protein UreD [ureD]. 16 278 25.464 T 09-03-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 ARZXY2_RS17560 988dfea68ef6cf567049b5a862ab993e 292 Pfam PF01774 UreD urease accessory protein 59 265 6.0E-44 T 09-03-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 ARZXY2_RS08725 26046fed34de38586e9150cae6b2cf14 277 SUPERFAMILY SSF53448 5 201 6.56E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08725 26046fed34de38586e9150cae6b2cf14 277 Gene3D G3DSA:3.90.550.10 8 110 2.2E-12 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08725 26046fed34de38586e9150cae6b2cf14 277 Pfam PF00535 Glycosyl transferase family 2 8 124 1.3E-13 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS10030 d8234a0ae0b740052cfbd8ff974878d6 388 Pfam PF12698 ABC-2 family transporter protein 22 377 3.4E-22 T 09-03-2017 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 SUPERFAMILY SSF51905 1 300 1.35E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 SUPERFAMILY SSF51905 425 458 1.35E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 6.7E-6 T 09-03-2017 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 6.7E-6 T 09-03-2017 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 Gene3D G3DSA:3.50.50.60 2 44 2.3E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 Gene3D G3DSA:3.50.50.60 93 140 2.3E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 Pfam PF01593 Flavin containing amine oxidoreductase 13 448 5.2E-10 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 Gene3D G3DSA:3.50.50.60 436 469 3.2E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS18650 0b3855efac3eb4a7796b3dcb1c63cd17 481 Gene3D G3DSA:3.50.50.60 203 280 3.2E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS11815 edfc0bc9498bddb39aa6b1e6cd195af1 176 Pfam PF01551 Peptidase family M23 59 160 1.1E-14 T 09-03-2017 IPR016047 Peptidase M23 ARZXY2_RS11815 edfc0bc9498bddb39aa6b1e6cd195af1 176 Gene3D G3DSA:2.70.70.10 24 165 6.6E-25 T 09-03-2017 ARZXY2_RS11815 edfc0bc9498bddb39aa6b1e6cd195af1 176 SUPERFAMILY SSF51261 25 163 5.23E-14 T 09-03-2017 IPR011055 Duplicated hybrid motif ARZXY2_RS10580 1cc1f3a1fdd087337a97d87f4a8cc5bd 403 Gene3D G3DSA:3.40.720.10 33 317 3.5E-38 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 ARZXY2_RS10580 1cc1f3a1fdd087337a97d87f4a8cc5bd 403 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 54 380 5.6E-36 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 ARZXY2_RS10580 1cc1f3a1fdd087337a97d87f4a8cc5bd 403 SUPERFAMILY SSF53649 50 393 3.49E-57 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 ARZXY2_RS22800 9a8d73a33c665d3c0c47510af999afdc 302 Gene3D G3DSA:1.50.10.10 242 301 6.5E-18 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS22800 9a8d73a33c665d3c0c47510af999afdc 302 SUPERFAMILY SSF48208 241 300 6.05E-17 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS22800 9a8d73a33c665d3c0c47510af999afdc 302 Pfam PF00723 Glycosyl hydrolases family 15 241 301 9.8E-10 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 ARZXY2_RS00045 e14eaf02b0bb03d8dc7fc5b5961f91e1 758 Pfam PF05425 Copper resistance protein D 270 369 6.6E-21 T 09-03-2017 IPR008457 Copper resistance protein D GO:0016021 ARZXY2_RS00045 e14eaf02b0bb03d8dc7fc5b5961f91e1 758 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 424 670 7.1E-78 T 09-03-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related ARZXY2_RS13755 ec033d312756a7f9a27548f40f6df0c9 326 SMART SM00797 24 314 3.4E-119 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS13755 ec033d312756a7f9a27548f40f6df0c9 326 SUPERFAMILY SSF50891 191 304 1.1E-8 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS13755 ec033d312756a7f9a27548f40f6df0c9 326 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 313 3.7E-80 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS13755 ec033d312756a7f9a27548f40f6df0c9 326 Gene3D G3DSA:2.40.100.10 198 309 1.4E-8 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS13755 ec033d312756a7f9a27548f40f6df0c9 326 Pfam PF02626 Allophanate hydrolase subunit 2 25 297 1.5E-80 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B ARZXY2_RS04710 cd3e836b87f526f1c0e3e73931bedc15 129 Pfam PF01817 Chorismate mutase type II 38 113 5.5E-18 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ARZXY2_RS04710 cd3e836b87f526f1c0e3e73931bedc15 129 Gene3D G3DSA:1.20.59.10 27 116 9.8E-19 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ARZXY2_RS04710 cd3e836b87f526f1c0e3e73931bedc15 129 SMART SM00830 38 118 4.9E-23 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ARZXY2_RS04710 cd3e836b87f526f1c0e3e73931bedc15 129 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 31 122 8.4E-42 T 09-03-2017 IPR010951 Chorismate mutase, bacteria ARZXY2_RS04710 cd3e836b87f526f1c0e3e73931bedc15 129 SUPERFAMILY SSF48600 28 117 6.26E-24 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 Gene3D G3DSA:3.40.630.30 7 126 1.2E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 Pfam PF02388 FemAB family 126 221 9.8E-8 T 09-03-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 Pfam PF02388 FemAB family 235 335 1.3E-11 T 09-03-2017 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 SUPERFAMILY SSF55729 6 155 1.38E-15 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 SUPERFAMILY SSF55729 151 337 2.01E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS14360 de9cb3ef1f40ae022952c5929b401163 357 Gene3D G3DSA:3.40.630.30 127 322 7.6E-44 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 SUPERFAMILY SSF54826 7 137 1.85E-27 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 38 135 3.2E-12 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 110 135 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 202 233 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 Gene3D G3DSA:3.20.20.120 139 359 4.5E-77 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 Gene3D G3DSA:3.30.390.10 8 138 1.0E-37 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 SUPERFAMILY SSF51604 123 362 2.36E-74 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 Pfam PF13378 Enolase C-terminal domain-like 158 360 1.9E-63 T 09-03-2017 IPR029065 Enolase C-terminal domain-like ARZXY2_RS18390 a67e52541ee51ef959a19b0b23baef8b 375 SMART SM00922 155 252 3.4E-25 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal ARZXY2_RS04430 b2ecc052a46f31b84bad60ec45a2bd58 265 SUPERFAMILY SSF110399 11 249 5.23E-80 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 ARZXY2_RS04430 b2ecc052a46f31b84bad60ec45a2bd58 265 Hamap MF_00443 Thiazole synthase [thiG]. 12 263 40.458 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 ARZXY2_RS04430 b2ecc052a46f31b84bad60ec45a2bd58 265 Pfam PF05690 Thiazole biosynthesis protein ThiG 15 256 4.8E-101 T 09-03-2017 ARZXY2_RS04430 b2ecc052a46f31b84bad60ec45a2bd58 265 Gene3D G3DSA:3.20.20.70 12 262 6.5E-57 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS00620 5c458e5db825ecc6ac5974a87ac78737 311 Pfam PF03793 PASTA domain 153 210 3.8E-11 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS00620 5c458e5db825ecc6ac5974a87ac78737 311 SMART SM00740 147 212 1.9E-10 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS00620 5c458e5db825ecc6ac5974a87ac78737 311 SMART SM00740 213 285 8.9 T 09-03-2017 IPR005543 PASTA domain ARZXY2_RS04000 51a80d029b919c6b109b3a0006cd8b9f 179 SUPERFAMILY SSF46785 42 115 2.57E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS04000 51a80d029b919c6b109b3a0006cd8b9f 179 Pfam PF03551 Transcriptional regulator PadR-like family 46 113 1.4E-21 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal ARZXY2_RS04000 51a80d029b919c6b109b3a0006cd8b9f 179 Gene3D G3DSA:1.10.10.10 32 115 1.9E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS11890 3c220837aa2b59b672ff1f8174620f5a 174 SUPERFAMILY SSF50249 6 174 8.81E-47 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11890 3c220837aa2b59b672ff1f8174620f5a 174 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.093 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS11890 3c220837aa2b59b672ff1f8174620f5a 174 Gene3D G3DSA:2.40.50.140 3 116 3.1E-42 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold ARZXY2_RS11890 3c220837aa2b59b672ff1f8174620f5a 174 Pfam PF00436 Single-strand binding protein family 6 107 1.2E-31 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 ARZXY2_RS11890 3c220837aa2b59b672ff1f8174620f5a 174 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 150 4.7E-35 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 ARZXY2_RS16720 0cdb1f40c71270fcdb8af809bb00ea4b 149 Pfam PF06262 Zinicin-like metallopeptidase 55 148 6.2E-34 T 09-03-2017 IPR010428 Zinicin-like metallopeptidase ARZXY2_RS16720 0cdb1f40c71270fcdb8af809bb00ea4b 149 SUPERFAMILY SSF55486 29 148 3.41E-34 T 09-03-2017 ARZXY2_RS14605 5c85a3cc77b2aefbf13c6643f76b8a22 128 Gene3D G3DSA:2.30.290.10 9 127 1.4E-25 T 09-03-2017 IPR024046 Flagellar assembly factor FliW domain ARZXY2_RS14605 5c85a3cc77b2aefbf13c6643f76b8a22 128 SUPERFAMILY SSF141457 9 126 1.83E-23 T 09-03-2017 IPR024046 Flagellar assembly factor FliW domain ARZXY2_RS14605 5c85a3cc77b2aefbf13c6643f76b8a22 128 Pfam PF02623 FliW protein 11 126 1.2E-21 T 09-03-2017 IPR003775 Flagellar assembly factor FliW GO:0044780 ARZXY2_RS02480 13345168376db0b967cfda83b7cf8f29 478 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 18 478 3.3E-127 T 09-03-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase ARZXY2_RS02480 13345168376db0b967cfda83b7cf8f29 478 Pfam PF02397 Bacterial sugar transferase 285 472 5.5E-58 T 09-03-2017 IPR003362 Bacterial sugar transferase ARZXY2_RS02465 4f7fee01bd9b5bc0e544db87d49a2c87 210 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 169 203 2.8E-4 T 09-03-2017 IPR019931 LPXTG cell wall anchor domain ARZXY2_RS04095 a8d7fcbbf0642cfbb32a7bc4686df3d5 242 Gene3D G3DSA:1.10.3720.10 12 193 1.3E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04095 a8d7fcbbf0642cfbb32a7bc4686df3d5 242 SUPERFAMILY SSF161098 11 194 5.76E-31 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04095 a8d7fcbbf0642cfbb32a7bc4686df3d5 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 202 5.3E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02995 bc5765730a2267c3c20f470bf263d9a4 158 SUPERFAMILY SSF46785 11 142 5.44E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02995 bc5765730a2267c3c20f470bf263d9a4 158 Gene3D G3DSA:1.10.10.10 12 87 4.4E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02995 bc5765730a2267c3c20f470bf263d9a4 158 Pfam PF01475 Ferric uptake regulator family 18 108 7.0E-16 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 ARZXY2_RS01855 e5059076cda405a32d7ed72147be1595 128 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 19 126 9.0E-24 T 09-03-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein ARZXY2_RS07725 11667f628dcf45c7bebd7b71d047deb7 125 SUPERFAMILY SSF51182 31 120 1.34E-11 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS07725 11667f628dcf45c7bebd7b71d047deb7 125 Gene3D G3DSA:2.60.120.10 11 120 6.0E-14 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS17310 2397d7fbd41508558634160104cf3806 384 SUPERFAMILY SSF56529 156 361 1.57E-22 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17310 2397d7fbd41508558634160104cf3806 384 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 215 358 1.6E-5 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS17310 2397d7fbd41508558634160104cf3806 384 Gene3D G3DSA:3.90.850.10 171 360 9.7E-20 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS00060 d9bbd289f1ccc72e71c471eebbb457c6 577 SUPERFAMILY SSF52540 33 407 9.55E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00060 d9bbd289f1ccc72e71c471eebbb457c6 577 Gene3D G3DSA:3.40.50.300 233 405 2.9E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00060 d9bbd289f1ccc72e71c471eebbb457c6 577 Gene3D G3DSA:3.40.50.300 36 136 2.9E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00060 d9bbd289f1ccc72e71c471eebbb457c6 577 Pfam PF05872 Bacterial protein of unknown function (DUF853) 38 454 1.4E-176 T 09-03-2017 IPR033186 Helicase HerA-like C-terminal ARZXY2_RS19310 ad7cdd71099c1dec870e5df187309e8e 418 Pfam PF13700 Domain of unknown function (DUF4158) 13 169 8.4E-24 T 09-03-2017 IPR025296 Domain of unknown function DUF4158 ARZXY2_RS01645 606046c6202173dfd17d5a5275ef571e 522 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 58 490 4.2E-82 T 09-03-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 ARZXY2_RS07285 a0dd0d3f9bd38081fcbe79aaf60b585e 140 Gene3D G3DSA:3.40.630.30 2 125 4.8E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS07285 a0dd0d3f9bd38081fcbe79aaf60b585e 140 Pfam PF00583 Acetyltransferase (GNAT) family 51 126 8.3E-18 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS07285 a0dd0d3f9bd38081fcbe79aaf60b585e 140 SUPERFAMILY SSF55729 1 130 2.29E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS11775 b019cdf0d23bf835a5d84cc3c53618f0 491 Pfam PF00474 Sodium:solute symporter family 34 417 2.1E-46 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 Pfam PF00962 Adenosine/AMP deaminase 14 331 2.1E-74 T 09-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 Gene3D G3DSA:3.20.20.140 14 335 1.5E-95 T 09-03-2017 ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 276 282 - T 09-03-2017 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 332 2.7E-109 T 09-03-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 SUPERFAMILY SSF51556 14 331 2.64E-78 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS13715 4e846ab9b1d6040e9c69ad1933639b8b 343 Hamap MF_01962 Adenine deaminase. 9 321 73.026 T 09-03-2017 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 ARZXY2_RS01030 217e5f33c75f55a81fc2fa856647bf10 202 SUPERFAMILY SSF51182 1 151 3.85E-44 T 09-03-2017 IPR011051 RmlC-like cupin domain ARZXY2_RS01030 217e5f33c75f55a81fc2fa856647bf10 202 Gene3D G3DSA:2.60.120.10 8 115 5.9E-34 T 09-03-2017 IPR014710 RmlC-like jelly roll fold ARZXY2_RS01030 217e5f33c75f55a81fc2fa856647bf10 202 Pfam PF05962 HutD 8 195 6.3E-52 T 09-03-2017 IPR010282 Uncharacterised protein family HutD/Ves ARZXY2_RS18080 6dfde2df540c0955cd3f9c8f8e9f8e82 386 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 190 312 8.8E-21 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 ARZXY2_RS18080 6dfde2df540c0955cd3f9c8f8e9f8e82 386 Gene3D G3DSA:3.40.50.2000 29 150 6.5E-15 T 09-03-2017 ARZXY2_RS18080 6dfde2df540c0955cd3f9c8f8e9f8e82 386 SUPERFAMILY SSF53756 29 377 1.99E-61 T 09-03-2017 ARZXY2_RS18080 6dfde2df540c0955cd3f9c8f8e9f8e82 386 Gene3D G3DSA:3.40.50.2000 196 378 1.8E-36 T 09-03-2017 ARZXY2_RS09500 1faba8aade34eadb29040bdd1ef8253c 181 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 4 178 3.8E-71 T 09-03-2017 IPR021441 Protein of unknown function DUF3090 ARZXY2_RS09500 1faba8aade34eadb29040bdd1ef8253c 181 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 1.6E-61 T 09-03-2017 IPR021441 Protein of unknown function DUF3090 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 SUPERFAMILY SSF53756 14 369 3.38E-94 T 09-03-2017 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 14 153 1.6E-32 T 09-03-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 Gene3D G3DSA:3.40.50.2000 202 370 2.7E-20 T 09-03-2017 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 200 360 3.8E-32 T 09-03-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 Gene3D G3DSA:3.40.50.2000 12 201 7.2E-59 T 09-03-2017 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 14 370 31.133 T 09-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS10845 c13c5a2eef24188b7d31e462c66b4622 372 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 12 365 6.2E-83 T 09-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 ARZXY2_RS08440 b6f8c359e166563641933f36812483e3 141 SUPERFAMILY SSF54593 1 134 4.95E-33 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS08440 b6f8c359e166563641933f36812483e3 141 Gene3D G3DSA:3.10.180.10 9 136 1.0E-41 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS08440 b6f8c359e166563641933f36812483e3 141 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 133 1.9E-13 T 09-03-2017 IPR028973 PhnB-like ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 PIRSF PIRSF004532 24 344 6.6E-139 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 26 336 4.0E-112 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 SUPERFAMILY SSF56655 24 336 2.33E-109 T 09-03-2017 ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 26 333 4.6E-137 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 Gene3D G3DSA:3.30.540.10 24 197 7.8E-64 T 09-03-2017 ARZXY2_RS12945 f8cf784e1bd01f7fda5161f175b176a1 345 Gene3D G3DSA:3.30.540.10 198 337 3.7E-39 T 09-03-2017 ARZXY2_RS13565 1902dbb6230c0b6bbe4f738259bebe66 123 Gene3D G3DSA:3.40.470.10 2 100 1.6E-4 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS14940 9e0a7742d34709c63d0f02867dd41001 394 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 390 3.8E-101 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS14940 9e0a7742d34709c63d0f02867dd41001 394 Gene3D G3DSA:3.40.640.10 13 259 7.8E-71 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS14940 9e0a7742d34709c63d0f02867dd41001 394 Gene3D G3DSA:3.90.1150.10 260 391 3.1E-36 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS14940 9e0a7742d34709c63d0f02867dd41001 394 SUPERFAMILY SSF53383 29 390 5.33E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS14940 9e0a7742d34709c63d0f02867dd41001 394 PIRSF PIRSF001434 2 393 4.2E-111 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS02165 2f717016a2097c608afde31e8394ef99 353 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 113 351 1.7E-70 T 09-03-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 ARZXY2_RS02165 2f717016a2097c608afde31e8394ef99 353 Pfam PF01578 Cytochrome C assembly protein 136 348 1.6E-42 T 09-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 ARZXY2_RS19120 e57a066a16189c4de5bae51b3c74a1c7 278 Pfam PF00005 ABC transporter 31 172 3.6E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS19120 e57a066a16189c4de5bae51b3c74a1c7 278 SMART SM00382 39 234 1.9E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS19120 e57a066a16189c4de5bae51b3c74a1c7 278 SUPERFAMILY SSF52540 10 242 6.1E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19120 e57a066a16189c4de5bae51b3c74a1c7 278 Gene3D G3DSA:3.40.50.300 4 227 6.1E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19120 e57a066a16189c4de5bae51b3c74a1c7 278 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 Gene3D G3DSA:1.10.10.10 589 649 6.6E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 SUPERFAMILY SSF46894 585 649 8.84E-16 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 Pfam PF00196 Bacterial regulatory proteins, luxR family 595 647 7.3E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 625 637 6.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 609 625 6.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 595 609 6.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS02175 d462f3627a4cec02a6f2179a2a2bf10a 661 SMART SM00421 592 649 2.7E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 Gene3D G3DSA:3.40.50.300 2 251 8.9E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 SUPERFAMILY SSF52540 5 246 5.7E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 Pfam PF00005 ABC transporter 21 177 2.1E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 259 1.4E-111 T 09-03-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 ARZXY2_RS17645 ed7564c8bd728e68dec5a47e51cb4ec9 259 SMART SM00382 29 230 6.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS09975 730d41d6e4b6834f03da451fea5123ae 109 Pfam PF11239 Protein of unknown function (DUF3040) 1 81 2.2E-13 T 09-03-2017 IPR021401 Protein of unknown function DUF3040 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 SMART SM00411 3 92 7.3E-28 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 SUPERFAMILY SSF47729 4 92 1.28E-23 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 Gene3D G3DSA:4.10.520.10 4 93 1.3E-26 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 Pfam PF00216 Bacterial DNA-binding protein 4 91 8.8E-24 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 6.8E-6 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 6.8E-6 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS00040 886f478bd0caaf29febd64aca0d4cfff 95 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 6.8E-6 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 ARZXY2_RS17450 53ea5ac1e0b363ac5ffd863da4684c2d 504 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 325 493 1.3E-34 T 09-03-2017 IPR031475 Putative nucleotide-binding C-terminal domain ARZXY2_RS17450 53ea5ac1e0b363ac5ffd863da4684c2d 504 Pfam PF07005 Putative sugar-binding N-terminal domain 41 297 7.8E-51 T 09-03-2017 IPR010737 Putative sugar-binding, N-terminal domain ARZXY2_RS17450 53ea5ac1e0b363ac5ffd863da4684c2d 504 SUPERFAMILY SSF142764 41 500 1.03E-66 T 09-03-2017 ARZXY2_RS10075 2da23b71e57b3c99799019d39e91fce2 294 SUPERFAMILY SSF51569 4 287 7.32E-59 T 09-03-2017 ARZXY2_RS10075 2da23b71e57b3c99799019d39e91fce2 294 Gene3D G3DSA:3.20.20.70 5 290 6.1E-85 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS10075 2da23b71e57b3c99799019d39e91fce2 294 PIRSF PIRSF037840 1 290 3.1E-130 T 09-03-2017 IPR017291 Sulfofructosephosphate aldolase, YihT GO:0061595|GO:1902777 MetaCyc: PWY-7446 ARZXY2_RS10075 2da23b71e57b3c99799019d39e91fce2 294 SMART SM01133 16 257 1.0E-6 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 ARZXY2_RS10075 2da23b71e57b3c99799019d39e91fce2 294 Pfam PF01791 DeoC/LacD family aldolase 17 256 2.0E-37 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 ARZXY2_RS12690 415565a84634557dff0e1f99535461e2 1002 Pfam PF01943 Polysaccharide biosynthesis protein 2 263 4.6E-6 T 09-03-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 ARZXY2_RS08905 65be07ca52e43f7e439621309ca30e9d 122 SUPERFAMILY SSF103196 2 117 7.85E-6 T 09-03-2017 ARZXY2_RS08905 65be07ca52e43f7e439621309ca30e9d 122 Gene3D G3DSA:3.30.450.30 3 119 0.001 T 09-03-2017 ARZXY2_RS10090 b06acdff5e352ce9201471882ac6d6a5 271 Gene3D G3DSA:1.10.3720.10 6 258 1.0E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS10090 b06acdff5e352ce9201471882ac6d6a5 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 264 7.0E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS10090 b06acdff5e352ce9201471882ac6d6a5 271 SUPERFAMILY SSF161098 7 271 2.9E-69 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS00575 a244fb2c7f266895a25d7a4bf831024b 96 SUPERFAMILY SSF143011 11 92 7.72E-16 T 09-03-2017 ARZXY2_RS00575 a244fb2c7f266895a25d7a4bf831024b 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 14 93 4.0E-7 T 09-03-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family ARZXY2_RS02010 363dbf188f658f946edd3bbc9c0973cd 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 301 5.5E-12 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02010 363dbf188f658f946edd3bbc9c0973cd 314 SUPERFAMILY SSF161098 73 300 2.35E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02010 363dbf188f658f946edd3bbc9c0973cd 314 SUPERFAMILY SSF160964 29 63 2.75E-6 T 09-03-2017 ARZXY2_RS02010 363dbf188f658f946edd3bbc9c0973cd 314 Gene3D G3DSA:1.10.3720.10 79 306 5.2E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02010 363dbf188f658f946edd3bbc9c0973cd 314 Gene3D G3DSA:1.20.58.370 29 63 5.0E-4 T 09-03-2017 ARZXY2_RS07775 c8b448277d9a475aaf4ea9cab6eb815d 329 Pfam PF02219 Methylenetetrahydrofolate reductase 17 300 3.2E-72 T 09-03-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ARZXY2_RS07775 c8b448277d9a475aaf4ea9cab6eb815d 329 Gene3D G3DSA:3.20.20.220 19 302 6.3E-88 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS07775 c8b448277d9a475aaf4ea9cab6eb815d 329 SUPERFAMILY SSF51730 20 300 5.69E-76 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS10690 b3f28b139a03e85b94b27d7c58fec6be 142 SUPERFAMILY SSF82784 5 136 1.06E-29 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS10690 b3f28b139a03e85b94b27d7c58fec6be 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 6.1E-50 T 09-03-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 ARZXY2_RS10690 b3f28b139a03e85b94b27d7c58fec6be 142 Pfam PF02566 OsmC-like protein 44 136 4.3E-16 T 09-03-2017 IPR003718 OsmC/Ohr family ARZXY2_RS10690 b3f28b139a03e85b94b27d7c58fec6be 142 Gene3D G3DSA:3.30.300.20 4 140 3.2E-42 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta ARZXY2_RS21595 3bad8e5d93da454e7d1d3fc16f8ecbb1 124 Pfam PF00176 SNF2 family N-terminal domain 54 123 2.1E-17 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 ARZXY2_RS21595 3bad8e5d93da454e7d1d3fc16f8ecbb1 124 Gene3D G3DSA:3.40.50.300 34 122 7.8E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS21595 3bad8e5d93da454e7d1d3fc16f8ecbb1 124 SUPERFAMILY SSF52540 26 122 9.57E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 Gene3D G3DSA:3.40.640.10 6 297 3.1E-111 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 PIRSF PIRSF001434 1 436 2.3E-129 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 Gene3D G3DSA:3.90.1150.10 299 435 4.2E-47 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 SUPERFAMILY SSF53383 5 432 2.15E-116 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 432 3.2E-136 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 ARZXY2_RS12245 122fa6e3c628df4ef5b2cd85c08cd228 438 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 432 2.7E-194 T 09-03-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 ARZXY2_RS18880 5b0c0ce58d272887ba2c9b9fcc74f60e 291 Pfam PF01261 Xylose isomerase-like TIM barrel 44 223 1.1E-22 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS18880 5b0c0ce58d272887ba2c9b9fcc74f60e 291 SUPERFAMILY SSF51658 6 271 3.18E-44 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS18880 5b0c0ce58d272887ba2c9b9fcc74f60e 291 Gene3D G3DSA:3.20.20.150 5 280 2.1E-46 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS10565 785e9c390c9004a6557779f034fd36e7 99 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 2.3E-41 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 ARZXY2_RS15245 ddc91c8c161aac5450428de159a79589 297 Gene3D G3DSA:3.40.50.2000 106 263 1.8E-16 T 09-03-2017 ARZXY2_RS15245 ddc91c8c161aac5450428de159a79589 297 SUPERFAMILY SSF53756 52 284 3.06E-42 T 09-03-2017 ARZXY2_RS15245 ddc91c8c161aac5450428de159a79589 297 Pfam PF00534 Glycosyl transferases group 1 106 262 4.2E-24 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 ARZXY2_RS06700 817a2eb013d86132f9939db6e96f3072 507 Pfam PF00916 Sulfate permease family 180 373 4.7E-26 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS06700 817a2eb013d86132f9939db6e96f3072 507 Pfam PF00916 Sulfate permease family 30 160 3.6E-23 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 ARZXY2_RS06700 817a2eb013d86132f9939db6e96f3072 507 Gene3D G3DSA:3.30.750.24 420 491 1.4E-8 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS06700 817a2eb013d86132f9939db6e96f3072 507 Pfam PF01740 STAS domain 423 491 9.1E-6 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS06700 817a2eb013d86132f9939db6e96f3072 507 SUPERFAMILY SSF52091 420 493 1.24E-10 T 09-03-2017 IPR002645 STAS domain ARZXY2_RS01445 aec574f83bb8a1cef92fac023b4ecba0 151 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 82 128 1.1E-13 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 ARZXY2_RS01445 aec574f83bb8a1cef92fac023b4ecba0 151 Pfam PF12728 Helix-turn-helix domain 82 129 1.0E-8 T 09-03-2017 ARZXY2_RS05430 5c61f6195bd40b39e879fd0c689bbf01 118 Pfam PF02656 Domain of unknown function (DUF202) 16 81 1.2E-16 T 09-03-2017 IPR003807 Domain of unknown function DUF202 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 16 316 1.4E-17 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 Pfam PF00698 Acyl transferase domain 16 293 2.0E-16 T 09-03-2017 IPR014043 Acyl transferase ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 SUPERFAMILY SSF55048 139 191 4.71E-10 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 Gene3D G3DSA:3.30.70.250 135 199 5.9E-20 T 09-03-2017 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 Gene3D G3DSA:3.40.366.10 13 131 6.9E-52 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 Gene3D G3DSA:3.40.366.10 200 307 6.9E-52 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 SUPERFAMILY SSF52151 193 315 3.4E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ARZXY2_RS07335 2d721429b57e8eaef67a7919265f9c39 320 SUPERFAMILY SSF52151 12 131 3.4E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ARZXY2_RS00735 0a136844884480166e7155575300d7ca 141 Pfam PF13411 MerR HTH family regulatory protein 10 74 3.8E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00735 0a136844884480166e7155575300d7ca 141 SUPERFAMILY SSF46955 9 94 5.49E-18 T 09-03-2017 IPR009061 Putative DNA-binding domain ARZXY2_RS00735 0a136844884480166e7155575300d7ca 141 SMART SM00422 8 76 2.4E-24 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 ARZXY2_RS00735 0a136844884480166e7155575300d7ca 141 Gene3D G3DSA:1.10.1660.10 10 98 5.1E-21 T 09-03-2017 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 Gene3D G3DSA:3.30.70.360 189 289 1.4E-25 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 Pfam PF01546 Peptidase family M20/M25/M40 72 370 3.7E-23 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 13 372 3.4E-156 T 09-03-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 SUPERFAMILY SSF53187 302 370 4.37E-43 T 09-03-2017 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 SUPERFAMILY SSF53187 19 196 4.37E-43 T 09-03-2017 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 Gene3D G3DSA:3.40.630.10 295 372 1.3E-46 T 09-03-2017 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 Gene3D G3DSA:3.40.630.10 14 188 1.3E-46 T 09-03-2017 ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 SUPERFAMILY SSF55031 188 288 3.89E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS04290 cd5dcadc4fb7979c3114808bd5b3023a 374 Pfam PF07687 Peptidase dimerisation domain 188 286 2.1E-17 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08010 2644f9d240713180b498316905263e29 496 Pfam PF03993 Domain of Unknown Function (DUF349) 174 244 2.3E-8 T 09-03-2017 IPR007139 Protein of unknown function DUF349 ARZXY2_RS08010 2644f9d240713180b498316905263e29 496 Pfam PF03993 Domain of Unknown Function (DUF349) 333 405 2.1E-20 T 09-03-2017 IPR007139 Protein of unknown function DUF349 ARZXY2_RS08010 2644f9d240713180b498316905263e29 496 Pfam PF03993 Domain of Unknown Function (DUF349) 256 329 3.0E-19 T 09-03-2017 IPR007139 Protein of unknown function DUF349 ARZXY2_RS12420 f3c41ec3d018b0790976ef865297d7fc 632 SUPERFAMILY SSF49879 534 624 8.39E-9 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 ARZXY2_RS12420 f3c41ec3d018b0790976ef865297d7fc 632 Gene3D G3DSA:2.60.200.20 530 622 2.3E-9 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 ARZXY2_RS16460 eaba675c56a4ae7ba5ff0713a0f40691 208 Pfam PF04961 Formiminotransferase-cyclodeaminase 6 181 2.8E-51 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 ARZXY2_RS16460 eaba675c56a4ae7ba5ff0713a0f40691 208 SUPERFAMILY SSF101262 2 206 7.06E-49 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 ARZXY2_RS08890 b22a9a6f43008678ad157b2c826839f2 261 Pfam PF01925 Sulfite exporter TauE/SafE 10 252 9.3E-38 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 ARZXY2_RS15965 9548b7aaafefa134c85ecf466d62e8ec 298 Gene3D G3DSA:3.20.20.370 106 295 3.7E-29 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS15965 9548b7aaafefa134c85ecf466d62e8ec 298 Pfam PF01522 Polysaccharide deacetylase 115 235 2.8E-19 T 09-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 ARZXY2_RS15965 9548b7aaafefa134c85ecf466d62e8ec 298 SUPERFAMILY SSF88713 105 293 4.25E-30 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS18180 f085c7a4cc3cca0db0f4dd3b34ac8423 477 SUPERFAMILY SSF75304 5 476 1.83E-117 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS18180 f085c7a4cc3cca0db0f4dd3b34ac8423 477 ProSitePatterns PS00571 Amidases signature. 163 194 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 ARZXY2_RS18180 f085c7a4cc3cca0db0f4dd3b34ac8423 477 Gene3D G3DSA:3.90.1300.10 6 476 4.5E-116 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS18180 f085c7a4cc3cca0db0f4dd3b34ac8423 477 Pfam PF01425 Amidase 33 468 3.5E-93 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 Pfam PF01958 Domain of unknown function DUF108 166 249 6.1E-21 T 09-03-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 SUPERFAMILY SSF51735 7 146 1.07E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 106 9.2E-12 T 09-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 PIRSF PIRSF005227 4 260 7.5E-58 T 09-03-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 Gene3D G3DSA:3.40.50.720 7 132 1.7E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 Gene3D G3DSA:3.30.360.10 133 233 4.3E-24 T 09-03-2017 ARZXY2_RS09525 1fc028497c5bedf8d8952edd09788217 264 SUPERFAMILY SSF55347 118 232 6.54E-18 T 09-03-2017 ARZXY2_RS10805 343ce5ff318dffc66d3976ab09359ab7 228 Pfam PF05103 DivIVA protein 3 104 1.0E-9 T 09-03-2017 IPR007793 DivIVA family ARZXY2_RS10805 343ce5ff318dffc66d3976ab09359ab7 228 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 37 1.5E-14 T 09-03-2017 IPR019933 DivIVA domain ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 Gene3D G3DSA:3.40.190.10 246 286 2.5E-30 T 09-03-2017 ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 Gene3D G3DSA:3.40.190.10 59 138 2.5E-30 T 09-03-2017 ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 SUPERFAMILY SSF53850 1 22 1.27E-47 T 09-03-2017 ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 SUPERFAMILY SSF53850 51 286 1.27E-47 T 09-03-2017 ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 SMART SM00062 61 287 8.4E-35 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 Gene3D G3DSA:3.40.190.10 139 243 1.3E-11 T 09-03-2017 ARZXY2_RS08490 ef63593375113e00854b77dc446de758 304 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 63 284 3.0E-45 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS07150 686d64ad6cb3a2ab62a828ca3c9070ff 498 Pfam PF13520 Amino acid permease 32 461 5.8E-32 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS07150 686d64ad6cb3a2ab62a828ca3c9070ff 498 PIRSF PIRSF006060 19 482 8.9E-54 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS05645 6e146d240afb68c3a0420e926540664e 936 Pfam PF02687 FtsX-like permease family 659 750 6.7E-7 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS05645 6e146d240afb68c3a0420e926540664e 936 Gene3D G3DSA:1.10.3720.10 777 853 2.2E-4 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03120 180d7e45cab285ea2199ed92bae3a055 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 307 9.3E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03120 180d7e45cab285ea2199ed92bae3a055 315 SUPERFAMILY SSF161098 78 303 1.26E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03120 180d7e45cab285ea2199ed92bae3a055 315 Gene3D G3DSA:1.10.3720.10 26 305 1.0E-44 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15630 ae711e5cb2821dc76b244c4df163486e 279 Gene3D G3DSA:1.10.3720.10 6 267 8.0E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15630 ae711e5cb2821dc76b244c4df163486e 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 272 3.1E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15630 ae711e5cb2821dc76b244c4df163486e 279 SUPERFAMILY SSF161098 5 279 1.78E-69 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09190 35003ec60445545ff82e3bc9568d1460 207 SUPERFAMILY SSF54637 91 205 1.2E-25 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09190 35003ec60445545ff82e3bc9568d1460 207 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 89 200 2.5E-26 T 09-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 ARZXY2_RS09190 35003ec60445545ff82e3bc9568d1460 207 Gene3D G3DSA:3.10.129.10 83 206 2.5E-39 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS09190 35003ec60445545ff82e3bc9568d1460 207 Pfam PF03061 Thioesterase superfamily 118 192 9.5E-13 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 SUPERFAMILY SSF55920 9 255 3.01E-71 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 Hamap MF_01974 Methionine aminopeptidase [map]. 8 257 34.95 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 174 192 - T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 168 180 2.3E-19 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 2.3E-19 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 2.3E-19 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 2.3E-19 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 Pfam PF00557 Metallopeptidase family M24 18 248 2.8E-46 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 8 255 3.3E-77 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 ARZXY2_RS03625 972c7b5b5e005094ae6af91c8c0f6ae6 275 Gene3D G3DSA:3.90.230.10 9 257 6.0E-79 T 09-03-2017 IPR000994 Peptidase M24, structural domain ARZXY2_RS12825 9353aaa5d8ca876f0197ee25772ce92c 498 Pfam PF01882 Protein of unknown function DUF58 204 298 3.0E-19 T 09-03-2017 IPR002881 Domain of unknown function DUF58 ARZXY2_RS14590 c9fc458d21a7c830395d49707e3af3e0 160 Gene3D G3DSA:1.20.58.300 4 132 1.1E-4 T 09-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 ARZXY2_RS14590 c9fc458d21a7c830395d49707e3af3e0 160 Pfam PF05130 FlgN protein 3 147 2.6E-16 T 09-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 ARZXY2_RS14590 c9fc458d21a7c830395d49707e3af3e0 160 SUPERFAMILY SSF140566 4 132 1.07E-6 T 09-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 ARZXY2_RS07985 ee0a92dbe54d38ecfc224b203c5d4733 142 SMART SM01323 14 96 1.8E-24 T 09-03-2017 IPR003849 Preprotein translocase YajC ARZXY2_RS07985 ee0a92dbe54d38ecfc224b203c5d4733 142 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 18 96 4.5E-17 T 09-03-2017 IPR003849 Preprotein translocase YajC ARZXY2_RS07985 ee0a92dbe54d38ecfc224b203c5d4733 142 Pfam PF02699 Preprotein translocase subunit 17 93 6.0E-20 T 09-03-2017 IPR003849 Preprotein translocase YajC ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 Gene3D G3DSA:2.40.100.10 99 231 6.0E-38 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 SUPERFAMILY SSF50891 99 228 7.96E-37 T 09-03-2017 IPR029000 Cyclophilin-like domain ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 SUPERFAMILY SSF160467 11 102 7.19E-12 T 09-03-2017 ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 SMART SM00796 9 212 2.8E-42 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 Pfam PF02682 Allophanate hydrolase subunit 1 10 209 2.0E-52 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D ARZXY2_RS19950 f01962dc134a423546f038dcf5bdb70a 245 Gene3D G3DSA:3.30.1360.40 10 81 2.2E-10 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain ARZXY2_RS00760 0fa31d49b66c8b35465ba56aa9ea0ac3 292 Gene3D G3DSA:3.20.20.150 2 282 1.1E-71 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00760 0fa31d49b66c8b35465ba56aa9ea0ac3 292 Pfam PF01261 Xylose isomerase-like TIM barrel 25 212 3.6E-20 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS00760 0fa31d49b66c8b35465ba56aa9ea0ac3 292 SUPERFAMILY SSF51658 3 278 6.28E-51 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS13135 9a180c2e0fe5cb76c82e16eecf2cf8fb 380 SUPERFAMILY SSF51556 16 376 5.73E-70 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS13135 9a180c2e0fe5cb76c82e16eecf2cf8fb 380 Gene3D G3DSA:3.20.20.140 16 375 2.3E-95 T 09-03-2017 ARZXY2_RS13135 9a180c2e0fe5cb76c82e16eecf2cf8fb 380 Pfam PF00962 Adenosine/AMP deaminase 19 369 5.8E-73 T 09-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 ARZXY2_RS03330 15260501181088e42f992b6ddb8d4942 240 Gene3D G3DSA:3.40.50.360 14 170 3.0E-15 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS03330 15260501181088e42f992b6ddb8d4942 240 SUPERFAMILY SSF52218 14 239 2.1E-30 T 09-03-2017 IPR029039 Flavoprotein-like domain ARZXY2_RS03330 15260501181088e42f992b6ddb8d4942 240 Pfam PF03358 NADPH-dependent FMN reductase 14 166 6.1E-13 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 ARZXY2_RS04610 5c7c6eebbe804f58899b38080beb68cb 267 Gene3D G3DSA:3.40.50.620 1 266 1.3E-79 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS04610 5c7c6eebbe804f58899b38080beb68cb 267 SUPERFAMILY SSF52402 1 262 1.47E-64 T 09-03-2017 ARZXY2_RS04610 5c7c6eebbe804f58899b38080beb68cb 267 PIRSF PIRSF000090 1 267 4.4E-76 T 09-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 ARZXY2_RS04610 5c7c6eebbe804f58899b38080beb68cb 267 Pfam PF01012 Electron transfer flavoprotein domain 27 215 1.8E-40 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 ARZXY2_RS04610 5c7c6eebbe804f58899b38080beb68cb 267 SMART SM00893 23 220 1.1E-46 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 ARZXY2_RS08705 7cbc90c327799fd68f6007cf19d29180 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 5.8E-139 T 09-03-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 ARZXY2_RS08705 7cbc90c327799fd68f6007cf19d29180 288 Gene3D G3DSA:3.90.550.10 1 257 4.6E-64 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08705 7cbc90c327799fd68f6007cf19d29180 288 SUPERFAMILY SSF53448 1 286 1.26E-81 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS08705 7cbc90c327799fd68f6007cf19d29180 288 Pfam PF00483 Nucleotidyl transferase 3 236 1.6E-61 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 ARZXY2_RS01330 71ac80af4dac608ec0abeef841ba570b 405 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 62 376 7.3E-32 T 09-03-2017 IPR003776 YcaO-like domain ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 Pfam PF02195 ParB-like nuclease domain 150 241 6.2E-23 T 09-03-2017 IPR003115 ParB/Sulfiredoxin ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 147 327 9.2E-58 T 09-03-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 SUPERFAMILY SSF110849 141 245 2.09E-30 T 09-03-2017 IPR003115 ParB/Sulfiredoxin ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 SUPERFAMILY SSF109709 234 344 2.62E-33 T 09-03-2017 ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 SMART SM00470 149 242 2.6E-33 T 09-03-2017 IPR003115 ParB/Sulfiredoxin ARZXY2_RS18605 d3e7446885bb5567bc4eff7021716620 414 Gene3D G3DSA:3.90.1530.10 143 248 7.2E-37 T 09-03-2017 ARZXY2_RS16680 c39c65c9fc62ffb0810f303957e5d8b5 364 Gene3D G3DSA:3.30.1540.10 198 280 9.3E-29 T 09-03-2017 ARZXY2_RS16680 c39c65c9fc62ffb0810f303957e5d8b5 364 Pfam PF02515 CoA-transferase family III 1 349 2.1E-111 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 ARZXY2_RS16680 c39c65c9fc62ffb0810f303957e5d8b5 364 SUPERFAMILY SSF89796 1 352 4.45E-109 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS16680 c39c65c9fc62ffb0810f303957e5d8b5 364 Gene3D G3DSA:3.40.50.10540 281 353 9.0E-82 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS16680 c39c65c9fc62ffb0810f303957e5d8b5 364 Gene3D G3DSA:3.40.50.10540 1 192 9.0E-82 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS04725 9b9b1bd89962b80ffeda7dbb2a4d9d0e 430 Pfam PF01882 Protein of unknown function DUF58 186 270 1.6E-21 T 09-03-2017 IPR002881 Domain of unknown function DUF58 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 30 411 42.779 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 34 410 8.9E-135 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 Pfam PF00202 Aminotransferase class-III 42 406 3.4E-107 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 SUPERFAMILY SSF53383 30 409 1.38E-117 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 Gene3D G3DSA:3.40.640.10 77 321 3.8E-85 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 Gene3D G3DSA:3.90.1150.10 324 411 7.5E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS11215 a565639e8da24839b3aafe7820a2f255 422 Gene3D G3DSA:3.90.1150.10 23 76 7.5E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS09155 1c93f7aef75cd938eba8e521729a3669 341 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 318 6.2E-116 T 09-03-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 ARZXY2_RS09155 1c93f7aef75cd938eba8e521729a3669 341 Pfam PF03741 Integral membrane protein TerC family 70 272 2.5E-53 T 09-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 ARZXY2_RS00410 f99612a5bb8445726a2a208b07408079 264 Pfam PF02361 Cobalt transport protein 13 220 9.6E-22 T 09-03-2017 IPR003339 ABC/ECF transporter, transmembrane component ARZXY2_RS06375 1a510d0efcbc50aa4b2cceca10692a62 641 Pfam PF01368 DHH family 65 195 6.2E-8 T 09-03-2017 IPR001667 DDH domain ARZXY2_RS06375 1a510d0efcbc50aa4b2cceca10692a62 641 SUPERFAMILY SSF64182 45 234 2.79E-52 T 09-03-2017 ARZXY2_RS06375 1a510d0efcbc50aa4b2cceca10692a62 641 SUPERFAMILY SSF64182 302 470 2.79E-52 T 09-03-2017 ARZXY2_RS12720 40c9f66d773226a486e388631f25982f 165 SUPERFAMILY SSF55961 2 163 5.39E-5 T 09-03-2017 ARZXY2_RS12720 40c9f66d773226a486e388631f25982f 165 Pfam PF10698 Protein of unknown function (DUF2505) 5 162 1.4E-40 T 09-03-2017 IPR019639 Protein of unknown function DUF2505 ARZXY2_RS17145 a6b158d7abe5fa63b2d9d5c469332026 409 Pfam PF01040 UbiA prenyltransferase family 143 389 7.0E-34 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 ARZXY2_RS17145 a6b158d7abe5fa63b2d9d5c469332026 409 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 4 91 1.4E-11 T 09-03-2017 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 ARZXY2_RS12135 89da0da788c3eeb8def320b0e1999117 282 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 25 134 6.7E-23 T 09-03-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III ARZXY2_RS10455 2ad46f6523c16a74af744fb90c5717f5 146 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 17 144 8.3E-51 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS10455 2ad46f6523c16a74af744fb90c5717f5 146 Gene3D G3DSA:2.170.150.20 12 143 7.6E-61 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS10455 2ad46f6523c16a74af744fb90c5717f5 146 Pfam PF01641 SelR domain 21 140 1.3E-52 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 ARZXY2_RS10455 2ad46f6523c16a74af744fb90c5717f5 146 SUPERFAMILY SSF51316 16 144 4.34E-56 T 09-03-2017 IPR011057 Mss4-like ARZXY2_RS01075 5bd15f55c3dbc2cd3e8fa030a63d090d 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 255 2.2E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01075 5bd15f55c3dbc2cd3e8fa030a63d090d 278 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 58 256 3.8E-66 T 09-03-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 ARZXY2_RS01075 5bd15f55c3dbc2cd3e8fa030a63d090d 278 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 35 253 2.1E-82 T 09-03-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS01075 5bd15f55c3dbc2cd3e8fa030a63d090d 278 SUPERFAMILY SSF161098 14 257 1.03E-50 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS01075 5bd15f55c3dbc2cd3e8fa030a63d090d 278 Gene3D G3DSA:1.10.3720.10 14 255 2.5E-47 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS07730 7c76a3acfcadd5b6923f5974d106a98a 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 316 322 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 ARZXY2_RS07730 7c76a3acfcadd5b6923f5974d106a98a 388 Pfam PF05175 Methyltransferase small domain 214 383 8.3E-47 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 ARZXY2_RS07730 7c76a3acfcadd5b6923f5974d106a98a 388 Gene3D G3DSA:3.40.50.150 212 386 2.2E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS07730 7c76a3acfcadd5b6923f5974d106a98a 388 SUPERFAMILY SSF53335 204 366 6.54E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS07350 529faf745303a00249797b4afa205c05 139 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 5.2E-54 T 09-03-2017 IPR021412 Protein of unknown function DUF3052 ARZXY2_RS08505 8eeb6fa79fbbccf42413e7913ef80b39 574 Pfam PF12696 TraM recognition site of TraD and TraG 411 498 1.1E-16 T 09-03-2017 IPR032689 TraD/TraG, TraM recognition site ARZXY2_RS08505 8eeb6fa79fbbccf42413e7913ef80b39 574 SUPERFAMILY SSF52540 123 543 2.07E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08505 8eeb6fa79fbbccf42413e7913ef80b39 574 Gene3D G3DSA:3.40.50.300 357 540 2.4E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08505 8eeb6fa79fbbccf42413e7913ef80b39 574 Gene3D G3DSA:3.40.50.300 133 233 2.4E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11030 1cb237c4435347ae048e8d00ed80410e 237 Hamap MF_00238 Cytidylate kinase [cmk]. 18 234 26.235 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 ARZXY2_RS11030 1cb237c4435347ae048e8d00ed80410e 237 Gene3D G3DSA:3.40.50.300 17 231 2.1E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11030 1cb237c4435347ae048e8d00ed80410e 237 SUPERFAMILY SSF52540 16 233 7.16E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS11030 1cb237c4435347ae048e8d00ed80410e 237 TIGRFAM TIGR00017 cmk: cytidylate kinase 18 228 3.2E-53 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 ARZXY2_RS11030 1cb237c4435347ae048e8d00ed80410e 237 Pfam PF02224 Cytidylate kinase 20 230 2.9E-55 T 09-03-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 Gene3D G3DSA:3.40.630.10 42 243 1.8E-58 T 09-03-2017 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 Gene3D G3DSA:3.40.630.10 418 480 1.8E-58 T 09-03-2017 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 Gene3D G3DSA:3.30.70.360 244 389 2.4E-37 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 Pfam PF01546 Peptidase family M20/M25/M40 118 472 2.6E-28 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 SUPERFAMILY SSF53187 34 233 3.71E-53 T 09-03-2017 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 SUPERFAMILY SSF53187 394 480 3.71E-53 T 09-03-2017 ARZXY2_RS08370 8da162a1ca0d72e219dd36858e684d2e 487 Pfam PF07687 Peptidase dimerisation domain 231 378 1.3E-17 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 Pfam PF03737 Demethylmenaquinone methyltransferase 276 438 3.9E-29 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 SUPERFAMILY SSF89562 272 446 4.06E-36 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 15 218 5.6E-46 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 Gene3D G3DSA:3.90.850.10 11 220 1.2E-58 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 SUPERFAMILY SSF56529 11 218 1.09E-51 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS09365 a446df4d49538364fa0ccc13741e0406 500 Gene3D G3DSA:3.50.30.40 274 446 2.3E-42 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS09120 f8e081bfa43ca27e80c9563a6b02b188 126 SUPERFAMILY SSF46785 14 103 2.63E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09120 f8e081bfa43ca27e80c9563a6b02b188 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 84 2.0E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS09120 f8e081bfa43ca27e80c9563a6b02b188 126 Gene3D G3DSA:1.10.10.10 14 85 3.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS09120 f8e081bfa43ca27e80c9563a6b02b188 126 SMART SM00345 25 84 1.1E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 ARZXY2_RS13320 19fefb43eccd61bbbb5de85f860e70a8 531 Pfam PF07905 Purine catabolism regulatory protein-like family 38 134 1.8E-19 T 09-03-2017 IPR012914 Purine catabolism PurC-like domain ARZXY2_RS13320 19fefb43eccd61bbbb5de85f860e70a8 531 Pfam PF13556 PucR C-terminal helix-turn-helix domain 464 521 3.5E-13 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS04775 a5d702157c9d8ea5744af9c3c9da14dd 429 Pfam PF06224 Winged helix DNA-binding domain 39 376 7.7E-71 T 09-03-2017 IPR009351 Protein of unknown function DUF1006 ARZXY2_RS03630 b25b7f3eb65e6ee0d9266e67fabbeb5b 448 Gene3D G3DSA:3.40.190.10 170 370 3.8E-40 T 09-03-2017 ARZXY2_RS03630 b25b7f3eb65e6ee0d9266e67fabbeb5b 448 SUPERFAMILY SSF53850 56 434 5.93E-71 T 09-03-2017 ARZXY2_RS03630 b25b7f3eb65e6ee0d9266e67fabbeb5b 448 Pfam PF13416 Bacterial extracellular solute-binding protein 71 384 4.1E-41 T 09-03-2017 ARZXY2_RS19385 a9c3181347616a5dc36b056519284b4b 271 Gene3D G3DSA:2.70.70.10 220 258 9.4E-4 T 09-03-2017 ARZXY2_RS19385 a9c3181347616a5dc36b056519284b4b 271 SUPERFAMILY SSF51261 225 258 9.42E-6 T 09-03-2017 IPR011055 Duplicated hybrid motif ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 Gene3D G3DSA:3.30.390.50 243 291 2.5E-4 T 09-03-2017 ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 Gene3D G3DSA:3.30.465.10 71 170 3.2E-18 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 SUPERFAMILY SSF56176 19 162 7.94E-30 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 21 170 1.4E-27 T 09-03-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 SUPERFAMILY SSF55447 193 289 5.94E-5 T 09-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal ARZXY2_RS09610 e718754ab35ecb81b2c462d3e19b71d7 297 Gene3D G3DSA:3.30.43.10 19 66 1.3E-5 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 ARZXY2_RS20165 fbf9f29a0d92f6695ac215c88dc2e74d 426 PRINTS PR01217 Proline rich extensin signature 330 351 8.9E-9 T 09-03-2017 ARZXY2_RS20165 fbf9f29a0d92f6695ac215c88dc2e74d 426 PRINTS PR01217 Proline rich extensin signature 378 395 8.9E-9 T 09-03-2017 ARZXY2_RS20165 fbf9f29a0d92f6695ac215c88dc2e74d 426 PRINTS PR01217 Proline rich extensin signature 310 322 8.9E-9 T 09-03-2017 ARZXY2_RS20165 fbf9f29a0d92f6695ac215c88dc2e74d 426 PRINTS PR01217 Proline rich extensin signature 361 377 8.9E-9 T 09-03-2017 ARZXY2_RS20165 fbf9f29a0d92f6695ac215c88dc2e74d 426 PRINTS PR01217 Proline rich extensin signature 270 282 8.9E-9 T 09-03-2017 ARZXY2_RS19410 32b01cb5d10ac4be4d20825b7f94090d 336 Pfam PF09084 NMT1/THI5 like 50 262 4.8E-43 T 09-03-2017 IPR015168 SsuA/THI5-like ARZXY2_RS19410 32b01cb5d10ac4be4d20825b7f94090d 336 Gene3D G3DSA:3.40.190.10 122 259 3.6E-9 T 09-03-2017 ARZXY2_RS19410 32b01cb5d10ac4be4d20825b7f94090d 336 SUPERFAMILY SSF53850 42 327 1.84E-30 T 09-03-2017 ARZXY2_RS13490 4a5c01e97cc77201123182921fedf766 480 Pfam PF11855 Protein of unknown function (DUF3375) 9 476 2.4E-133 T 09-03-2017 IPR021804 Protein of unknown function DUF3375 ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 139 1.6E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 172 1.6E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.6E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 194 1.6E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 Gene3D G3DSA:3.40.50.1000 9 224 7.4E-34 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 210 5.8E-23 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 SUPERFAMILY SSF56784 10 233 7.54E-40 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS05705 9855fbce2daa9efb766a52400db9fb02 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 120 207 1.4E-9 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 SUPERFAMILY SSF51679 13 439 4.12E-92 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 26 438 1.5E-111 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 PIRSF PIRSF000337 9 442 3.2E-123 T 09-03-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 Gene3D G3DSA:3.20.20.30 357 439 3.8E-98 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 Gene3D G3DSA:3.20.20.30 12 319 3.8E-98 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00460 02a179418c2bb7bf86d12da851f470c3 442 Pfam PF00296 Luciferase-like monooxygenase 34 395 6.7E-48 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS20160 076651083bb0f0537e1351874154ec8c 306 Pfam PF03547 Membrane transport protein 8 138 2.4E-8 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ARZXY2_RS20160 076651083bb0f0537e1351874154ec8c 306 Pfam PF03547 Membrane transport protein 156 300 9.5E-18 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ARZXY2_RS11280 74316820b8363519cdbd9aac4d2584c1 400 Gene3D G3DSA:1.20.1250.20 21 199 9.0E-26 T 09-03-2017 ARZXY2_RS11280 74316820b8363519cdbd9aac4d2584c1 400 SUPERFAMILY SSF103473 13 396 7.72E-55 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS11280 74316820b8363519cdbd9aac4d2584c1 400 Gene3D G3DSA:1.20.1250.20 213 389 6.3E-14 T 09-03-2017 ARZXY2_RS11280 74316820b8363519cdbd9aac4d2584c1 400 Pfam PF07690 Major Facilitator Superfamily 24 303 3.7E-30 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 SUPERFAMILY SSF51735 7 240 3.29E-81 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 Gene3D G3DSA:3.40.50.720 2 239 2.9E-85 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.6E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 237 1.3E-68 T 09-03-2017 ARZXY2_RS09915 9f9bbbfb8d2fcfa067727dbaa9cc7dc2 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 ARZXY2_RS05695 3fc6d63da83bea0f9a0bca293fe2ce77 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 55 6.7E-15 T 09-03-2017 IPR018833 Domain of unknown function DUF2437 ARZXY2_RS05695 3fc6d63da83bea0f9a0bca293fe2ce77 258 SUPERFAMILY SSF56529 50 256 3.92E-79 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS05695 3fc6d63da83bea0f9a0bca293fe2ce77 258 Gene3D G3DSA:3.90.850.10 52 257 1.2E-88 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS05695 3fc6d63da83bea0f9a0bca293fe2ce77 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 61 256 3.0E-66 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 ARZXY2_RS06895 a76c21fa08191e7f4712b230a84b4693 64 SUPERFAMILY SSF53041 13 54 1.83E-7 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS06895 a76c21fa08191e7f4712b230a84b4693 64 Gene3D G3DSA:3.40.50.1390 11 53 5.2E-8 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS06895 a76c21fa08191e7f4712b230a84b4693 64 Pfam PF00239 Resolvase, N terminal domain 11 54 3.6E-7 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 ARZXY2_RS17185 3cf3b8977eb419bd8710c446b72d4be0 207 SUPERFAMILY SSF53474 4 200 4.32E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17185 3cf3b8977eb419bd8710c446b72d4be0 207 Gene3D G3DSA:3.40.50.1820 5 200 1.2E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17185 3cf3b8977eb419bd8710c446b72d4be0 207 Pfam PF02230 Phospholipase/Carboxylesterase 12 201 7.3E-11 T 09-03-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 ARZXY2_RS10935 973000946543fc2d70e17ced6b8a390d 267 Pfam PF01553 Acyltransferase 23 151 8.9E-22 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS10935 973000946543fc2d70e17ced6b8a390d 267 SUPERFAMILY SSF69593 2 217 1.02E-49 T 09-03-2017 ARZXY2_RS10935 973000946543fc2d70e17ced6b8a390d 267 Gene3D G3DSA:3.40.1130.10 3 206 4.8E-32 T 09-03-2017 ARZXY2_RS10935 973000946543fc2d70e17ced6b8a390d 267 SMART SM00563 35 154 2.9E-33 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 ARZXY2_RS16845 e2547d2d545861d745bfa795ca80f46e 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 98 8.8E-10 T 09-03-2017 IPR008407 Branched-chain amino acid transport, AzlD ARZXY2_RS03000 fb4b3f9ac3018eee5d1adbd3c57ff53a 274 SUPERFAMILY SSF54197 6 111 4.89E-5 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 ARZXY2_RS17705 8cf56667b31e90708718ccc440d1738d 161 Gene3D G3DSA:3.40.630.30 1 157 1.4E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17705 8cf56667b31e90708718ccc440d1738d 161 SUPERFAMILY SSF55729 1 155 9.92E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17705 8cf56667b31e90708718ccc440d1738d 161 Pfam PF00583 Acetyltransferase (GNAT) family 55 128 2.1E-11 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 9.3E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 226 240 9.3E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 9.3E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 9.3E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 Pfam PF12146 Serine aminopeptidase, S33 41 262 5.6E-15 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 SUPERFAMILY SSF53474 14 282 4.75E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS17080 75ee4a79c62ad378c2c9c2cd9b98f369 287 Gene3D G3DSA:3.40.50.1820 16 281 3.0E-57 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS06475 c946e21f5ce410ad1a16e66574ad6827 60 Pfam PF02467 Transcription factor WhiB 1 60 2.3E-23 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS06475 c946e21f5ce410ad1a16e66574ad6827 60 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 6 60 13.176 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS10200 89373ed0e38241fc3c40c289d6fe1bd0 330 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 4.7E-172 T 09-03-2017 IPR015004 Protein of unknown function DUF1852 ARZXY2_RS10200 89373ed0e38241fc3c40c289d6fe1bd0 330 PIRSF PIRSF034367 1 327 9.1E-167 T 09-03-2017 IPR015004 Protein of unknown function DUF1852 ARZXY2_RS19710 b783f757934a134a866f337928756ed6 414 Pfam PF13657 HipA N-terminal domain 21 122 2.4E-7 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 ARZXY2_RS19710 b783f757934a134a866f337928756ed6 414 Pfam PF07804 HipA-like C-terminal domain 243 381 2.4E-22 T 09-03-2017 IPR012893 HipA-like, C-terminal ARZXY2_RS19710 b783f757934a134a866f337928756ed6 414 Pfam PF07805 HipA-like N-terminal domain 170 237 6.5E-8 T 09-03-2017 IPR012894 HipA, N-terminal subdomain 2 ARZXY2_RS02590 8bc51629c014c6845fbb720c458a9bda 420 SUPERFAMILY SSF53756 19 408 6.28E-32 T 09-03-2017 ARZXY2_RS02590 8bc51629c014c6845fbb720c458a9bda 420 Pfam PF13579 Glycosyl transferase 4-like domain 36 217 8.9E-15 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 ARZXY2_RS02590 8bc51629c014c6845fbb720c458a9bda 420 Pfam PF13692 Glycosyl transferases group 1 238 375 5.9E-8 T 09-03-2017 ARZXY2_RS19970 aa742a7526e6fdb6b936cca58388bca4 139 Gene3D G3DSA:3.10.129.10 4 116 5.0E-21 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS19970 aa742a7526e6fdb6b936cca58388bca4 139 Pfam PF03061 Thioesterase superfamily 17 88 2.2E-13 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 ARZXY2_RS19970 aa742a7526e6fdb6b936cca58388bca4 139 SUPERFAMILY SSF54637 3 118 5.69E-24 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS06620 5189b4241a07d36511450a6a223d9dba 164 SUPERFAMILY SSF56784 14 160 1.43E-17 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS06620 5189b4241a07d36511450a6a223d9dba 164 Gene3D G3DSA:3.40.50.1000 14 160 1.4E-25 T 09-03-2017 IPR023214 HAD-like domain ARZXY2_RS11630 bd4e6c045c3c58cf20e91867db966ae5 487 Pfam PF06762 Lipase maturation factor 124 276 3.4E-51 T 09-03-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 ARZXY2_RS11630 bd4e6c045c3c58cf20e91867db966ae5 487 Pfam PF06762 Lipase maturation factor 293 477 2.6E-58 T 09-03-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 ARZXY2_RS18355 31b3281bb78e56a83d117d005df8a2f6 126 SUPERFAMILY SSF54593 2 126 2.15E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS18355 31b3281bb78e56a83d117d005df8a2f6 126 Gene3D G3DSA:3.10.180.10 1 125 3.5E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS18355 31b3281bb78e56a83d117d005df8a2f6 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 122 3.6E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS07200 beaf8f903682659682b129f091512a48 236 SUPERFAMILY SSF52317 12 229 4.74E-45 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07200 beaf8f903682659682b129f091512a48 236 Gene3D G3DSA:3.40.50.880 15 222 6.7E-45 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07200 beaf8f903682659682b129f091512a48 236 Pfam PF00117 Glutamine amidotransferase class-I 39 178 3.6E-16 T 09-03-2017 IPR017926 Glutamine amidotransferase ARZXY2_RS19400 41358231d9d72667ae4d40107c6bdf6b 261 Pfam PF01695 IstB-like ATP binding protein 67 238 2.6E-54 T 09-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 ARZXY2_RS19400 41358231d9d72667ae4d40107c6bdf6b 261 SMART SM00382 108 239 2.2E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain ARZXY2_RS19400 41358231d9d72667ae4d40107c6bdf6b 261 Gene3D G3DSA:3.40.50.300 80 239 2.5E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19400 41358231d9d72667ae4d40107c6bdf6b 261 SUPERFAMILY SSF52540 103 223 5.32E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS19400 41358231d9d72667ae4d40107c6bdf6b 261 PIRSF PIRSF003073 12 256 1.2E-63 T 09-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein ARZXY2_RS15865 288cc58fcbc12ce51c3dad20e8ad5a6f 129 SUPERFAMILY SSF55399 45 119 6.41E-18 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15865 288cc58fcbc12ce51c3dad20e8ad5a6f 129 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 49 110 6.0E-7 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15865 288cc58fcbc12ce51c3dad20e8ad5a6f 129 Gene3D G3DSA:3.30.350.10 12 119 1.6E-16 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 ARZXY2_RS15995 928f4866f8aea4bee7bfc493b84ac168 301 SUPERFAMILY SSF161098 27 301 1.78E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15995 928f4866f8aea4bee7bfc493b84ac168 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 290 2.0E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15995 928f4866f8aea4bee7bfc493b84ac168 301 Gene3D G3DSA:1.10.3720.10 23 288 1.4E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 14 371 59.115 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 Pfam PF00814 Glycoprotease family 36 345 6.1E-89 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 17 345 4.7E-97 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 180 201 1.2E-29 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 17 30 1.2E-29 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 168 1.2E-29 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 302 311 1.2E-29 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 SUPERFAMILY SSF53067 15 104 4.75E-38 T 09-03-2017 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 SUPERFAMILY SSF53067 136 347 4.75E-38 T 09-03-2017 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 Gene3D G3DSA:3.30.420.40 15 185 3.3E-41 T 09-03-2017 ARZXY2_RS03840 c7d308ab35a978859f5a9ee8c5086c2c 378 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 16 351 2.2E-121 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 ARZXY2_RS20460 0fb700efa294652c3e58172096993734 330 SUPERFAMILY SSF56601 30 151 1.06E-5 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS20460 0fb700efa294652c3e58172096993734 330 SUPERFAMILY SSF56601 199 218 1.06E-5 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS20460 0fb700efa294652c3e58172096993734 330 Pfam PF06089 L-asparaginase II 19 322 6.2E-110 T 09-03-2017 IPR010349 L-asparaginase II ARZXY2_RS11785 972719f81e204a9b634d8e6134e384a5 194 TIGRFAM TIGR03543 divI1A_rptt_fam: DivIVA domain repeat protein 13 194 6.3E-74 T 09-03-2017 IPR019932 Conserved hypothetical protein CHP03543 ARZXY2_RS11785 972719f81e204a9b634d8e6134e384a5 194 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 155 188 3.5E-9 T 09-03-2017 IPR019933 DivIVA domain ARZXY2_RS11785 972719f81e204a9b634d8e6134e384a5 194 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 51 82 1.1E-9 T 09-03-2017 IPR019933 DivIVA domain ARZXY2_RS05610 c01027757bdb28cac217977b202353ed 384 Pfam PF07995 Glucose / Sorbosone dehydrogenase 77 373 8.6E-78 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 ARZXY2_RS05610 c01027757bdb28cac217977b202353ed 384 Gene3D G3DSA:2.120.10.30 61 371 1.2E-85 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS05610 c01027757bdb28cac217977b202353ed 384 Gene3D G3DSA:2.120.10.30 19 26 1.2E-85 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like ARZXY2_RS05610 c01027757bdb28cac217977b202353ed 384 SUPERFAMILY SSF50952 60 371 4.97E-41 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 ARZXY2_RS12745 5416e73f72ce72d6a6efd96db2ec24e4 807 Gene3D G3DSA:3.40.50.300 26 174 1.5E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12745 5416e73f72ce72d6a6efd96db2ec24e4 807 SUPERFAMILY SSF52540 21 78 2.04E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS12745 5416e73f72ce72d6a6efd96db2ec24e4 807 SUPERFAMILY SSF52540 105 204 2.04E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS17525 24b154f06b9807e6cd90e765798e2732 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 226 2.9E-19 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS17525 24b154f06b9807e6cd90e765798e2732 348 Gene3D G3DSA:3.40.50.720 13 309 8.6E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS17525 24b154f06b9807e6cd90e765798e2732 348 SUPERFAMILY SSF51735 12 319 1.55E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05095 2b39bbde3aa8b406275a1d44d63b7c5f 360 Gene3D G3DSA:3.40.50.1100 54 146 3.3E-21 T 09-03-2017 ARZXY2_RS05095 2b39bbde3aa8b406275a1d44d63b7c5f 360 Gene3D G3DSA:3.40.50.1100 147 340 1.6E-37 T 09-03-2017 ARZXY2_RS05095 2b39bbde3aa8b406275a1d44d63b7c5f 360 SUPERFAMILY SSF53686 28 339 6.02E-68 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS05095 2b39bbde3aa8b406275a1d44d63b7c5f 360 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 318 3.1E-49 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS08095 4feba5231b710500abb0b9a28ed6bb40 173 SUPERFAMILY SSF48452 53 145 5.84E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS08095 4feba5231b710500abb0b9a28ed6bb40 173 Gene3D G3DSA:1.25.40.10 52 166 5.7E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS02200 98ee0a828ac37423ed63006653c65759 147 Pfam PF13396 Phospholipase_D-nuclease N-terminal 13 57 1.1E-13 T 09-03-2017 IPR027379 Cardiolipin synthase N-terminal ARZXY2_RS01475 b5dc81b2a2d050552bf11af415b1f10f 666 Gene3D G3DSA:2.130.10.130 153 412 5.1E-8 T 09-03-2017 ARZXY2_RS01475 b5dc81b2a2d050552bf11af415b1f10f 666 SUPERFAMILY SSF69318 165 431 2.09E-12 T 09-03-2017 ARZXY2_RS13690 f2ce2e2a531972e46f0973985cc2aad9 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 318 1.2E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13690 f2ce2e2a531972e46f0973985cc2aad9 324 Gene3D G3DSA:1.10.3720.10 88 317 1.4E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS13690 f2ce2e2a531972e46f0973985cc2aad9 324 SUPERFAMILY SSF161098 85 308 6.02E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20480 3ac93361f1ac69bf55fafa6afefbdeae 86 SUPERFAMILY SSF47413 19 75 1.69E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS20480 3ac93361f1ac69bf55fafa6afefbdeae 86 Gene3D G3DSA:1.10.260.40 18 76 1.7E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 ARZXY2_RS20480 3ac93361f1ac69bf55fafa6afefbdeae 86 SMART SM00530 22 77 6.8E-11 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 ARZXY2_RS20480 3ac93361f1ac69bf55fafa6afefbdeae 86 Pfam PF13560 Helix-turn-helix domain 19 75 2.5E-12 T 09-03-2017 ARZXY2_RS10570 b088e40888f0509e1615f960f3bd4b9d 455 Pfam PF11268 Protein of unknown function (DUF3071) 1 185 2.4E-50 T 09-03-2017 IPR021421 Protein of unknown function DUF3071 ARZXY2_RS19110 ffa1ae548296584f090a84410d4def09 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 266 3.1E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19110 ffa1ae548296584f090a84410d4def09 279 Gene3D G3DSA:1.10.3720.10 71 266 1.8E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS19110 ffa1ae548296584f090a84410d4def09 279 SUPERFAMILY SSF161098 75 259 6.93E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS18965 5b316d237056bac2f9f30be081a5b0a0 120 Pfam PF02583 Metal-sensitive transcriptional repressor 30 115 9.9E-31 T 09-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 ARZXY2_RS20400 b8756a81b530066126c9b3cd0bfd06e0 323 SUPERFAMILY SSF48452 183 261 1.14E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS20400 b8756a81b530066126c9b3cd0bfd06e0 323 SUPERFAMILY SSF48452 101 136 1.14E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS20400 b8756a81b530066126c9b3cd0bfd06e0 323 Gene3D G3DSA:1.25.40.10 184 282 4.2E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS20400 b8756a81b530066126c9b3cd0bfd06e0 323 Gene3D G3DSA:1.25.40.10 107 136 4.2E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 ARZXY2_RS08830 ea3665ae835832fe2bac7e7748bb4768 230 Gene3D G3DSA:1.10.357.10 22 222 7.3E-33 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS08830 ea3665ae835832fe2bac7e7748bb4768 230 SUPERFAMILY SSF48498 104 200 1.11E-5 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal ARZXY2_RS08830 ea3665ae835832fe2bac7e7748bb4768 230 SUPERFAMILY SSF46689 26 108 1.28E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS08830 ea3665ae835832fe2bac7e7748bb4768 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 4.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS00085 0caca54bce83fbf211a61e699f23c370 324 Gene3D G3DSA:3.40.190.10 63 186 5.9E-29 T 09-03-2017 ARZXY2_RS00085 0caca54bce83fbf211a61e699f23c370 324 Gene3D G3DSA:3.40.190.10 187 259 3.5E-12 T 09-03-2017 ARZXY2_RS00085 0caca54bce83fbf211a61e699f23c370 324 SUPERFAMILY SSF53850 63 306 4.5E-39 T 09-03-2017 ARZXY2_RS00085 0caca54bce83fbf211a61e699f23c370 324 SMART SM00062 77 308 1.4E-19 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS00085 0caca54bce83fbf211a61e699f23c370 324 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 78 305 3.3E-34 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF ARZXY2_RS16625 de2aeae5f980fcfffa96c66dc030bd3b 141 Pfam PF03780 Asp23 family, cell envelope-related function 13 119 1.5E-25 T 09-03-2017 IPR005531 Alkaline shock protein Asp23 ARZXY2_RS04640 75b786cf92f3d2c14dbec8d6068fb948 155 Gene3D G3DSA:3.40.1280.10 2 153 2.9E-57 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal ARZXY2_RS04640 75b786cf92f3d2c14dbec8d6068fb948 155 Pfam PF00588 SpoU rRNA Methylase family 3 141 1.2E-29 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 ARZXY2_RS04640 75b786cf92f3d2c14dbec8d6068fb948 155 PIRSF PIRSF029256 1 154 3.8E-58 T 09-03-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 ARZXY2_RS04640 75b786cf92f3d2c14dbec8d6068fb948 155 SUPERFAMILY SSF75217 2 152 2.75E-41 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases ARZXY2_RS04640 75b786cf92f3d2c14dbec8d6068fb948 155 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 30.948 T 09-03-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 ARZXY2_RS06980 c84a07f119463dae46961a86c15c0f54 240 Gene3D G3DSA:3.40.50.1820 4 216 6.5E-13 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS06980 c84a07f119463dae46961a86c15c0f54 240 SUPERFAMILY SSF53474 4 217 9.15E-15 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS06980 c84a07f119463dae46961a86c15c0f54 240 Pfam PF12697 Alpha/beta hydrolase family 6 224 7.6E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 ARZXY2_RS15755 3327ed5732ef15f5f8ba37bde1665d32 471 Pfam PF11380 Stealth protein CR2, conserved region 2 200 304 3.7E-40 T 09-03-2017 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 ARZXY2_RS15755 3327ed5732ef15f5f8ba37bde1665d32 471 Pfam PF17101 Stealth protein CR1, conserved region 1 162 184 1.6E-9 T 09-03-2017 IPR031358 Stealth protein CR1, conserved region 1 ARZXY2_RS15755 3327ed5732ef15f5f8ba37bde1665d32 471 Pfam PF17102 Stealth protein CR3, conserved region 3 350 396 2.3E-15 T 09-03-2017 IPR031357 Stealth protein CR3, conserved region 3 ARZXY2_RS15755 3327ed5732ef15f5f8ba37bde1665d32 471 Pfam PF17103 Stealth protein CR4, conserved region 4 427 471 3.6E-13 T 09-03-2017 IPR031356 Stealth protein CR4, conserved region 4 ARZXY2_RS04935 40226bd834859e7ad05fdb3d4f1fba0a 147 Pfam PF07811 TadE-like protein 19 61 5.6E-7 T 09-03-2017 IPR012495 TadE-like ARZXY2_RS10825 afdb5c061027a563e8c28b408a639a03 239 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 18 236 2.3E-50 T 09-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase ARZXY2_RS10825 afdb5c061027a563e8c28b408a639a03 239 Gene3D G3DSA:3.60.140.10 8 237 9.5E-66 T 09-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase ARZXY2_RS10825 afdb5c061027a563e8c28b408a639a03 239 SUPERFAMILY SSF64438 15 237 1.43E-52 T 09-03-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic ARZXY2_RS12730 e6eb4a07a12c299ae646a5e25243cf01 439 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 29 415 20.781 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS12730 e6eb4a07a12c299ae646a5e25243cf01 439 Pfam PF06965 Na+/H+ antiporter 1 32 409 5.2E-131 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS12730 e6eb4a07a12c299ae646a5e25243cf01 439 Gene3D G3DSA:1.20.1530.10 29 415 3.1E-134 T 09-03-2017 IPR023171 Na/H antiporter domain ARZXY2_RS12730 e6eb4a07a12c299ae646a5e25243cf01 439 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 33 408 2.1E-95 T 09-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 ARZXY2_RS03930 1fd466cc7880f45fd69a7787704dc1de 162 Gene3D G3DSA:3.40.930.10 11 155 1.5E-34 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS03930 1fd466cc7880f45fd69a7787704dc1de 162 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 12 155 1.3E-29 T 09-03-2017 IPR002178 PTS EIIA type-2 domain ARZXY2_RS03930 1fd466cc7880f45fd69a7787704dc1de 162 SUPERFAMILY SSF55804 11 154 2.49E-28 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 ARZXY2_RS16320 93b14847bb6b086a1820d2ca7a20e379 169 Gene3D G3DSA:1.10.10.10 17 165 1.0E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16320 93b14847bb6b086a1820d2ca7a20e379 169 SUPERFAMILY SSF46785 27 161 1.89E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS16320 93b14847bb6b086a1820d2ca7a20e379 169 Pfam PF12802 MarR family 54 113 5.0E-9 T 09-03-2017 ARZXY2_RS16320 93b14847bb6b086a1820d2ca7a20e379 169 SMART SM00347 48 149 1.2E-21 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 Gene3D G3DSA:3.40.640.10 83 300 6.1E-11 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 Gene3D G3DSA:3.40.640.10 494 727 9.1E-37 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 4 946 24.274 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 SUPERFAMILY SSF53383 19 437 6.86E-98 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 SUPERFAMILY SSF53383 919 942 1.49E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 SUPERFAMILY SSF53383 465 876 1.49E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 13 940 0.0 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 Pfam PF02347 Glycine cleavage system P-protein 467 727 2.3E-11 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS14400 96a7617d73714bfa707844a527a0a519 948 Pfam PF02347 Glycine cleavage system P-protein 12 440 7.4E-173 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 ARZXY2_RS19040 fb252568fb2048358930118e5270f4df 168 Pfam PF00582 Universal stress protein family 13 157 9.3E-14 T 09-03-2017 IPR006016 UspA GO:0006950 ARZXY2_RS19040 fb252568fb2048358930118e5270f4df 168 Gene3D G3DSA:3.40.50.620 22 159 5.5E-15 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS19040 fb252568fb2048358930118e5270f4df 168 SUPERFAMILY SSF52402 21 163 1.34E-17 T 09-03-2017 ARZXY2_RS04925 e0aadd415d67a91cfe61af2fa6e4d7ce 313 Pfam PF00482 Type II secretion system (T2SS), protein F 178 300 1.4E-17 T 09-03-2017 IPR018076 Type II secretion system F domain ARZXY2_RS17835 e54d3b28550b258592b39cf683e892f8 169 Gene3D G3DSA:3.40.630.30 3 143 4.1E-29 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS17835 e54d3b28550b258592b39cf683e892f8 169 Pfam PF00583 Acetyltransferase (GNAT) family 52 122 1.2E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 ARZXY2_RS17835 e54d3b28550b258592b39cf683e892f8 169 SUPERFAMILY SSF55729 5 124 1.61E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS05200 d96ddf9127c360c92b0e878bf25c02e8 281 Pfam PF01300 Telomere recombination 23 201 6.0E-39 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 ARZXY2_RS05200 d96ddf9127c360c92b0e878bf25c02e8 281 Gene3D G3DSA:3.90.870.10 5 213 5.9E-58 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS05200 d96ddf9127c360c92b0e878bf25c02e8 281 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 209 2.4E-45 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 ARZXY2_RS05200 d96ddf9127c360c92b0e878bf25c02e8 281 SUPERFAMILY SSF55821 4 214 5.19E-49 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain ARZXY2_RS12125 737e4c8ea3eaa630597f7bcde1e360c3 300 Pfam PF05653 Magnesium transporter NIPA 5 147 8.7E-11 T 09-03-2017 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 Reactome: R-HSA-5223345 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 Gene3D G3DSA:3.40.605.10 10 267 1.1E-87 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 Pfam PF00171 Aldehyde dehydrogenase family 26 484 2.9E-137 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 SUPERFAMILY SSF53720 4 490 1.83E-147 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 Gene3D G3DSA:3.40.309.10 268 449 2.0E-64 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 ARZXY2_RS14075 cd29c37625b5a702c7e10f6a50ba42b7 504 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 11 488 8.5E-221 T 09-03-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 ARZXY2_RS04700 a36431ee748493d55b9354728bc5443e 322 SUPERFAMILY SSF161098 85 274 1.05E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04700 a36431ee748493d55b9354728bc5443e 322 Gene3D G3DSA:1.10.3720.10 80 287 6.0E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS04700 a36431ee748493d55b9354728bc5443e 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 294 6.0E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09845 87c1be68040fe560f3b33251d8384778 155 Gene3D G3DSA:2.30.110.10 6 142 8.5E-43 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09845 87c1be68040fe560f3b33251d8384778 155 SUPERFAMILY SSF50475 8 134 6.73E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS09845 87c1be68040fe560f3b33251d8384778 155 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 133 1.4E-25 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 Gene3D G3DSA:3.90.180.10 3 146 8.2E-43 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 SUPERFAMILY SSF51735 110 277 2.44E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 5.4E-11 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 SUPERFAMILY SSF50129 3 143 6.13E-37 T 09-03-2017 IPR011032 GroES-like ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 SMART SM00829 11 319 1.9E-30 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 Pfam PF00107 Zinc-binding dehydrogenase 150 251 9.3E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 ARZXY2_RS11240 a954eb793fcbe0628c697443048578a7 321 Gene3D G3DSA:3.40.50.720 147 249 1.3E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03700 50c0c0cd3fbdbcc94d55d7eddb0ed832 399 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 147 350 2.5E-17 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain ARZXY2_RS03700 50c0c0cd3fbdbcc94d55d7eddb0ed832 399 Gene3D G3DSA:3.40.50.300 143 380 5.6E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS03700 50c0c0cd3fbdbcc94d55d7eddb0ed832 399 SUPERFAMILY SSF52540 144 382 9.08E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02505 7b5e745acb57d4f9c9cdb62e8394e631 379 Pfam PF04230 Polysaccharide pyruvyl transferase 16 308 4.2E-19 T 09-03-2017 IPR007345 Polysaccharide pyruvyl transferase ARZXY2_RS03955 5d3452ea241f133af9964f0b4f403c16 206 SMART SM00858 24 86 8.7E-6 T 09-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 ARZXY2_RS03955 5d3452ea241f133af9964f0b4f403c16 206 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 95 193 1.6E-9 T 09-03-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain ARZXY2_RS04665 054b5c99a200b257683953855ea4879c 408 Gene3D G3DSA:3.40.640.10 17 251 2.1E-76 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS04665 054b5c99a200b257683953855ea4879c 408 SUPERFAMILY SSF53383 3 380 9.04E-93 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS04665 054b5c99a200b257683953855ea4879c 408 PIRSF PIRSF005572 1 386 8.1E-111 T 09-03-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ARZXY2_RS04665 054b5c99a200b257683953855ea4879c 408 Gene3D G3DSA:3.90.1150.10 252 378 1.5E-40 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS04665 054b5c99a200b257683953855ea4879c 408 Pfam PF00266 Aminotransferase class-V 3 372 2.7E-60 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS05910 49e67e9047548f6456384853c659e3f6 218 SUPERFAMILY SSF52141 43 203 3.01E-7 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 ARZXY2_RS00955 d22d0ba59991a652d1522a941324797f 220 Pfam PF13490 Putative zinc-finger 6 37 2.4E-10 T 09-03-2017 IPR027383 Putative zinc-finger ARZXY2_RS13165 acd1b01f7be6a2f4174dd3ecb5a399af 455 Pfam PF02653 Branched-chain amino acid transport system / permease component 145 420 1.2E-42 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS02280 bf4b8f68a7e3b771378c0981db48d41e 264 SUPERFAMILY SSF52096 7 254 1.14E-61 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS02280 bf4b8f68a7e3b771378c0981db48d41e 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 249 5.8E-45 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 ARZXY2_RS02280 bf4b8f68a7e3b771378c0981db48d41e 264 Gene3D G3DSA:3.90.226.10 4 249 2.8E-64 T 09-03-2017 IPR029045 ClpP/crotonase-like domain ARZXY2_RS07340 c25ad5152873ccf9db37e72657b90ae9 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 336 393 4.5E-19 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS06730 dd1c5af73db267797a753a75af3ce066 105 SUPERFAMILY SSF56091 2 100 5.47E-13 T 09-03-2017 ARZXY2_RS06730 dd1c5af73db267797a753a75af3ce066 105 Gene3D G3DSA:3.30.470.30 1 65 1.1E-11 T 09-03-2017 ARZXY2_RS06730 dd1c5af73db267797a753a75af3ce066 105 Pfam PF01068 ATP dependent DNA ligase domain 6 101 1.2E-8 T 09-03-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 ARZXY2_RS00630 3d781e04ad9b00b36b8c5ef0e1af4483 185 Pfam PF09684 Phage tail protein (Tail_P2_I) 27 168 4.4E-7 T 09-03-2017 IPR006521 Tail protein I ARZXY2_RS00630 3d781e04ad9b00b36b8c5ef0e1af4483 185 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 14 137 2.0E-15 T 09-03-2017 IPR011748 Uncharacterised protein family, phage tail-like ARZXY2_RS20450 20687cb952f9e6c1b407983c313b1dca 502 ProSitePatterns PS00218 Amino acid permeases signature. 61 91 - T 09-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 ARZXY2_RS20450 20687cb952f9e6c1b407983c313b1dca 502 PIRSF PIRSF006060 13 490 6.4E-61 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS20450 20687cb952f9e6c1b407983c313b1dca 502 Pfam PF00324 Amino acid permease 37 454 2.1E-104 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS12650 1f64d4f9bfa901dee7ca3a0a2d8ee8b9 160 Pfam PF08592 Domain of unknown function (DUF1772) 21 147 4.9E-6 T 09-03-2017 IPR013901 Protein of unknown function DUF1772 ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 Gene3D G3DSA:1.10.10.10 1 83 1.8E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.7E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 Gene3D G3DSA:3.40.190.10 90 187 1.1E-11 T 09-03-2017 ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 Gene3D G3DSA:3.40.190.10 188 266 6.8E-13 T 09-03-2017 ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 SUPERFAMILY SSF53850 89 299 3.08E-27 T 09-03-2017 ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 Pfam PF03466 LysR substrate binding domain 89 297 2.2E-28 T 09-03-2017 IPR005119 LysR, substrate-binding ARZXY2_RS15200 8a3819ee05bc460c0679e8759d5929ee 310 SUPERFAMILY SSF46785 1 112 1.44E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS15615 bf2b872aaf688fbb5e85cc0c7b078f01 380 SUPERFAMILY SSF55347 143 303 2.45E-25 T 09-03-2017 ARZXY2_RS15615 bf2b872aaf688fbb5e85cc0c7b078f01 380 Gene3D G3DSA:3.40.50.720 14 153 6.3E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS15615 bf2b872aaf688fbb5e85cc0c7b078f01 380 Gene3D G3DSA:3.30.360.10 154 359 6.5E-23 T 09-03-2017 ARZXY2_RS15615 bf2b872aaf688fbb5e85cc0c7b078f01 380 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 18 131 1.4E-13 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS15615 bf2b872aaf688fbb5e85cc0c7b078f01 380 SUPERFAMILY SSF51735 13 160 7.42E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS21035 0e744de7ed9552f3fb6a7e54c7ec4f60 149 SUPERFAMILY SSF103473 9 142 4.71E-8 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS21035 0e744de7ed9552f3fb6a7e54c7ec4f60 149 Pfam PF11700 Vacuole effluxer Atg22 like 38 143 2.3E-8 T 09-03-2017 IPR024671 Autophagy-related protein 22-like ARZXY2_RS03940 d13996ab27401ad5c632db238296e790 166 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 97 148 2.2E-13 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane ARZXY2_RS03940 d13996ab27401ad5c632db238296e790 166 Pfam PF12823 Domain of unknown function (DUF3817) 33 149 5.5E-28 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane ARZXY2_RS09890 15160c5e84b7d495d5e2358c4a74e302 84 SUPERFAMILY SSF47336 2 78 2.62E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS09890 15160c5e84b7d495d5e2358c4a74e302 84 Pfam PF00550 Phosphopantetheine attachment site 7 76 4.2E-7 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS09890 15160c5e84b7d495d5e2358c4a74e302 84 Gene3D G3DSA:1.10.1200.10 2 78 1.3E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain ARZXY2_RS03620 7c022f996cbd8d24aa4eb0d2c1afed7e 303 SUPERFAMILY SSF51735 1 289 1.07E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03620 7c022f996cbd8d24aa4eb0d2c1afed7e 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 198 5.5E-22 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS03620 7c022f996cbd8d24aa4eb0d2c1afed7e 303 Gene3D G3DSA:3.40.50.720 1 290 1.2E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS12910 0a9840cd294ec0b931d1b9d499caa828 231 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 8 228 8.6E-72 T 09-03-2017 IPR017523 Conserved hypothetical protein CHP03089 ARZXY2_RS12910 0a9840cd294ec0b931d1b9d499caa828 231 SUPERFAMILY SSF56801 16 228 7.59E-7 T 09-03-2017 ARZXY2_RS19775 5e972be7f1c102106c72d11a7f1119da 76 Gene3D G3DSA:1.10.287.90 20 71 0.001 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS00165 9ed535fef491aa6979749131769c9bee 329 Gene3D G3DSA:3.20.20.30 3 322 4.0E-84 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00165 9ed535fef491aa6979749131769c9bee 329 SUPERFAMILY SSF51679 4 322 1.57E-77 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00165 9ed535fef491aa6979749131769c9bee 329 Pfam PF00296 Luciferase-like monooxygenase 13 294 3.1E-38 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00165 9ed535fef491aa6979749131769c9bee 329 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 322 8.7E-125 T 09-03-2017 IPR019949 Luciferase family oxidoreductase, group 1 ARZXY2_RS13680 21b3712d342a4513cacd6d5b0ca14150 549 Gene3D G3DSA:3.40.190.10 193 401 3.7E-50 T 09-03-2017 ARZXY2_RS13680 21b3712d342a4513cacd6d5b0ca14150 549 Gene3D G3DSA:3.40.190.10 494 545 3.7E-50 T 09-03-2017 ARZXY2_RS13680 21b3712d342a4513cacd6d5b0ca14150 549 SUPERFAMILY SSF53850 32 545 8.69E-80 T 09-03-2017 ARZXY2_RS13680 21b3712d342a4513cacd6d5b0ca14150 549 Gene3D G3DSA:3.40.190.10 93 187 1.2E-10 T 09-03-2017 ARZXY2_RS13680 21b3712d342a4513cacd6d5b0ca14150 549 Pfam PF13416 Bacterial extracellular solute-binding protein 89 400 7.4E-22 T 09-03-2017 ARZXY2_RS06665 ce2971d7922d47a7bf5ad28832aaed95 366 PIRSF PIRSF005508 8 366 2.0E-135 T 09-03-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 ARZXY2_RS06665 ce2971d7922d47a7bf5ad28832aaed95 366 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 21 349 2.9E-126 T 09-03-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 ARZXY2_RS06665 ce2971d7922d47a7bf5ad28832aaed95 366 Pfam PF01758 Sodium Bile acid symporter family 66 262 3.7E-59 T 09-03-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 ARZXY2_RS08770 4e41be5e53d19df8dd109597f910c209 390 Gene3D G3DSA:3.40.640.10 13 259 5.2E-73 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS08770 4e41be5e53d19df8dd109597f910c209 390 SUPERFAMILY SSF53383 12 386 5.01E-99 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS08770 4e41be5e53d19df8dd109597f910c209 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 21 382 1.0E-104 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase ARZXY2_RS08770 4e41be5e53d19df8dd109597f910c209 390 PIRSF PIRSF000390 9 390 1.9E-98 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase ARZXY2_RS08770 4e41be5e53d19df8dd109597f910c209 390 Gene3D G3DSA:3.90.1150.10 263 386 5.5E-23 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 51 69 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 SUPERFAMILY SSF53686 24 342 3.93E-90 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 322 9.3E-66 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 Gene3D G3DSA:3.40.50.1100 171 341 8.2E-64 T 09-03-2017 ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 Gene3D G3DSA:3.40.50.1100 24 60 8.2E-64 T 09-03-2017 ARZXY2_RS00470 e2b4d1783e2757d2d88295529873cc18 353 Gene3D G3DSA:3.40.50.1100 61 162 1.8E-32 T 09-03-2017 ARZXY2_RS00975 916cc1a8d3fa186fa4d5c561b515e412 411 Gene3D G3DSA:1.20.1250.20 19 211 2.8E-16 T 09-03-2017 ARZXY2_RS00975 916cc1a8d3fa186fa4d5c561b515e412 411 Gene3D G3DSA:1.20.1250.20 232 402 2.1E-12 T 09-03-2017 ARZXY2_RS00975 916cc1a8d3fa186fa4d5c561b515e412 411 Pfam PF07690 Major Facilitator Superfamily 31 367 5.8E-18 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS00975 916cc1a8d3fa186fa4d5c561b515e412 411 SUPERFAMILY SSF103473 12 407 1.14E-40 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS01750 e286d72e1b5b7dfa5f106690db12d736 445 Pfam PF01547 Bacterial extracellular solute-binding protein 46 355 1.3E-21 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS01750 e286d72e1b5b7dfa5f106690db12d736 445 Gene3D G3DSA:3.40.190.10 30 160 2.8E-21 T 09-03-2017 ARZXY2_RS01750 e286d72e1b5b7dfa5f106690db12d736 445 SUPERFAMILY SSF53850 19 444 1.09E-64 T 09-03-2017 ARZXY2_RS01750 e286d72e1b5b7dfa5f106690db12d736 445 Gene3D G3DSA:3.40.190.10 161 374 4.0E-27 T 09-03-2017 ARZXY2_RS13160 d3d434130ec67a857df59f50a9158924 429 Pfam PF02653 Branched-chain amino acid transport system / permease component 133 409 1.1E-37 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS12490 bb69a2ea02634e77b1a8df03882f56d0 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 30 557 4.4E-159 T 09-03-2017 IPR010281 Protein of unknown function DUF885 ARZXY2_RS10135 a4cfcfaeea0d2db1f4350f65f47dcc01 213 Gene3D G3DSA:1.20.1260.10 62 211 6.6E-52 T 09-03-2017 IPR012347 Ferritin-related ARZXY2_RS10135 a4cfcfaeea0d2db1f4350f65f47dcc01 213 Pfam PF03713 Domain of unknown function (DUF305) 69 210 4.5E-46 T 09-03-2017 IPR005183 Domain of unknown function DUF305 ARZXY2_RS00125 e32b9ec179e9da87101cc11259e1d3b2 299 Pfam PF01925 Sulfite exporter TauE/SafE 9 246 1.0E-52 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 ARZXY2_RS12635 145c04d56b2ac587ae99ca6ceaad79bd 668 Gene3D G3DSA:3.60.21.10 192 358 2.2E-8 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS12635 145c04d56b2ac587ae99ca6ceaad79bd 668 SUPERFAMILY SSF56300 100 389 7.27E-12 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like ARZXY2_RS05720 bf5e658268348258adc0f791352b698f 373 Gene3D G3DSA:3.40.50.300 171 255 1.4E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05720 bf5e658268348258adc0f791352b698f 373 Gene3D G3DSA:3.40.50.300 75 119 1.4E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05720 bf5e658268348258adc0f791352b698f 373 Pfam PF00350 Dynamin family 77 212 3.6E-9 T 09-03-2017 IPR022812 Dynamin superfamily ARZXY2_RS05720 bf5e658268348258adc0f791352b698f 373 SUPERFAMILY SSF52540 59 266 4.62E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS14250 cf94d571d10e41c34e7b5a29006e5f1a 216 Pfam PF11228 Protein of unknown function (DUF3027) 89 164 3.3E-27 T 09-03-2017 IPR021391 Protein of unknown function DUF3027 ARZXY2_RS15230 395557adafd5837f1255006a32983dca 125 Gene3D G3DSA:3.10.180.10 9 116 3.5E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS15230 395557adafd5837f1255006a32983dca 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 115 6.9E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS15230 395557adafd5837f1255006a32983dca 125 SUPERFAMILY SSF54593 5 120 1.75E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS11665 9a1dffd4a83d61c15f9d56255ffd3cfd 233 SUPERFAMILY SSF52317 6 233 1.65E-41 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11665 9a1dffd4a83d61c15f9d56255ffd3cfd 233 Gene3D G3DSA:3.40.50.880 5 233 6.4E-55 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS11665 9a1dffd4a83d61c15f9d56255ffd3cfd 233 Pfam PF06283 Trehalose utilisation 8 231 1.8E-41 T 09-03-2017 IPR029010 ThuA-like domain ARZXY2_RS08175 6c0ad0966d08e29f3489129a7cb9b981 713 SUPERFAMILY SSF52540 210 337 3.6E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08175 6c0ad0966d08e29f3489129a7cb9b981 713 Gene3D G3DSA:3.40.50.300 209 333 4.0E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08175 6c0ad0966d08e29f3489129a7cb9b981 713 Hamap MF_00983 Probable primosomal protein N' [priA]. 42 712 18.535 T 09-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 ARZXY2_RS08430 90fd2205d134cf141057e6bd8aa67125 92 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 2.2E-15 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS08430 90fd2205d134cf141057e6bd8aa67125 92 Gene3D G3DSA:3.30.70.920 3 78 1.2E-24 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain ARZXY2_RS08430 90fd2205d134cf141057e6bd8aa67125 92 SUPERFAMILY SSF54909 2 78 1.93E-18 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS04150 31a5db1a5d0e1351a089a1174a1ec895 325 Pfam PF13175 AAA ATPase domain 140 213 7.8E-11 T 09-03-2017 ARZXY2_RS04150 31a5db1a5d0e1351a089a1174a1ec895 325 Gene3D G3DSA:3.40.50.300 101 229 1.6E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS04150 31a5db1a5d0e1351a089a1174a1ec895 325 SUPERFAMILY SSF52540 96 230 1.3E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS08035 51f7091de7bb4f32f2c21fedcb651fe1 210 SUPERFAMILY SSF53137 76 199 2.75E-18 T 09-03-2017 ARZXY2_RS10410 3786258ef02fd00af1639bfb362c8736 484 Pfam PF13520 Amino acid permease 32 441 7.5E-52 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS10410 3786258ef02fd00af1639bfb362c8736 484 PIRSF PIRSF006060 12 482 1.7E-90 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS03705 34bba3f7e037ab2dc21f6587a0d1b4e7 255 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 233 2.5E-7 T 09-03-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain ARZXY2_RS19615 48e200a0944401e41a815b74e6952da9 253 Gene3D G3DSA:3.20.20.220 25 250 5.6E-39 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS19615 48e200a0944401e41a815b74e6952da9 253 SUPERFAMILY SSF51730 5 251 5.3E-44 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like ARZXY2_RS19615 48e200a0944401e41a815b74e6952da9 253 Pfam PF02219 Methylenetetrahydrofolate reductase 39 182 1.1E-16 T 09-03-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 ARZXY2_RS15790 3ecf17a8ca4579ce3b1e09ce7531feda 107 Gene3D G3DSA:3.30.70.830 3 104 1.0E-39 T 09-03-2017 ARZXY2_RS15790 3ecf17a8ca4579ce3b1e09ce7531feda 107 SUPERFAMILY SSF102705 4 104 3.33E-24 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 ARZXY2_RS15175 32a6c70038f8e241e9f3ed8869d4c025 235 SUPERFAMILY SSF52540 16 191 8.96E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS02455 2fbbbaaf889a02987bab80f71276de1d 744 Gene3D G3DSA:3.90.550.10 341 515 3.7E-14 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02455 2fbbbaaf889a02987bab80f71276de1d 744 Gene3D G3DSA:3.90.550.10 103 184 3.7E-14 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02455 2fbbbaaf889a02987bab80f71276de1d 744 Pfam PF13632 Glycosyl transferase family group 2 342 561 6.4E-28 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 ARZXY2_RS02455 2fbbbaaf889a02987bab80f71276de1d 744 SUPERFAMILY SSF53448 287 550 8.7E-23 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS02455 2fbbbaaf889a02987bab80f71276de1d 744 SUPERFAMILY SSF53448 100 153 8.7E-23 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS01775 a7d5b5f358eb28c9035c677882bfee19 450 Pfam PF02687 FtsX-like permease family 66 179 3.6E-8 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS08950 823d58f6d198e1168c38bd814ce6b8d8 211 PIRSF PIRSF016661 10 201 5.3E-40 T 09-03-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 ARZXY2_RS08950 823d58f6d198e1168c38bd814ce6b8d8 211 Pfam PF02632 BioY family 48 192 6.4E-34 T 09-03-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 ARZXY2_RS14500 3e3af3f56abc2847a531fd7202f53b4d 390 Pfam PF00460 Flagella basal body rod protein 5 35 2.5E-11 T 09-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 ARZXY2_RS14500 3e3af3f56abc2847a531fd7202f53b4d 390 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 371 1.5E-88 T 09-03-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G ARZXY2_RS14500 3e3af3f56abc2847a531fd7202f53b4d 390 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 311 388 1.2E-21 T 09-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain ARZXY2_RS14500 3e3af3f56abc2847a531fd7202f53b4d 390 SUPERFAMILY SSF117143 92 350 6.15E-56 T 09-03-2017 ARZXY2_RS13890 275474d8353026bd47ecee8654d92df8 421 SUPERFAMILY SSF89796 28 420 8.89E-122 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS13890 275474d8353026bd47ecee8654d92df8 421 Pfam PF02515 CoA-transferase family III 33 397 7.8E-113 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 ARZXY2_RS13890 275474d8353026bd47ecee8654d92df8 421 Gene3D G3DSA:3.30.1540.10 255 329 2.1E-10 T 09-03-2017 ARZXY2_RS13890 275474d8353026bd47ecee8654d92df8 421 Gene3D G3DSA:3.40.50.10540 330 420 1.4E-110 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS13890 275474d8353026bd47ecee8654d92df8 421 Gene3D G3DSA:3.40.50.10540 29 244 1.4E-110 T 09-03-2017 IPR023606 CoA-transferase family III domain ARZXY2_RS13455 f1258facf0757338676b7d40ce6d94b3 248 Gene3D G3DSA:2.60.40.1240 114 232 5.5E-8 T 09-03-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain ARZXY2_RS01050 38ecc4cace23e499545c24c2ad2aafe7 575 SUPERFAMILY SSF50939 17 390 1.04E-81 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS01050 38ecc4cace23e499545c24c2ad2aafe7 575 Gene3D G3DSA:2.120.10.10 314 392 6.0E-73 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS01050 38ecc4cace23e499545c24c2ad2aafe7 575 Gene3D G3DSA:2.120.10.10 24 281 6.0E-73 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS01050 38ecc4cace23e499545c24c2ad2aafe7 575 Pfam PF13088 BNR repeat-like domain 43 368 1.8E-20 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 ARZXY2_RS01190 4c6f319296160f34c1196aad177b819b 139 Pfam PF13581 Histidine kinase-like ATPase domain 17 133 7.1E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS19850 9e0486a12ad337d02b2da9b9786aa721 401 Pfam PF05048 Periplasmic copper-binding protein (NosD) 144 291 5.0E-9 T 09-03-2017 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain ARZXY2_RS19850 9e0486a12ad337d02b2da9b9786aa721 401 SUPERFAMILY SSF51126 13 231 3.52E-11 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor ARZXY2_RS19850 9e0486a12ad337d02b2da9b9786aa721 401 SUPERFAMILY SSF51126 313 362 3.52E-11 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor ARZXY2_RS03180 0e90759a2770dcc675aa685c3680347f 523 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 6 520 2.4E-90 T 09-03-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 ARZXY2_RS03180 0e90759a2770dcc675aa685c3680347f 523 Pfam PF00999 Sodium/hydrogen exchanger family 7 399 7.2E-49 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ARZXY2_RS04825 dfa63930902c5d4807d8bcc45b30afed 82 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.232 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS04825 dfa63930902c5d4807d8bcc45b30afed 82 Pfam PF02467 Transcription factor WhiB 3 71 3.1E-27 T 09-03-2017 IPR003482 Transcription factor WhiB ARZXY2_RS03985 4782f55917c7ad8aec48bce11cb62bde 266 SUPERFAMILY SSF51735 3 232 1.72E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03985 4782f55917c7ad8aec48bce11cb62bde 266 Gene3D G3DSA:3.40.50.720 4 212 1.9E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03985 4782f55917c7ad8aec48bce11cb62bde 266 Pfam PF13460 NAD(P)H-binding 8 187 5.3E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS11650 e185cc80c57e9186894a467b6ce338ed 301 SUPERFAMILY SSF161098 39 298 8.69E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11650 e185cc80c57e9186894a467b6ce338ed 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 286 3.7E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS11650 e185cc80c57e9186894a467b6ce338ed 301 Gene3D G3DSA:1.10.3720.10 42 287 3.6E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS18230 19d2c5799d72ea66967b67bd806c8636 188 Pfam PF01965 DJ-1/PfpI family 9 177 3.3E-53 T 09-03-2017 IPR002818 DJ-1/PfpI ARZXY2_RS18230 19d2c5799d72ea66967b67bd806c8636 188 SUPERFAMILY SSF52317 8 178 1.02E-51 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS18230 19d2c5799d72ea66967b67bd806c8636 188 Gene3D G3DSA:3.40.50.880 3 184 1.3E-60 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS18230 19d2c5799d72ea66967b67bd806c8636 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 177 3.3E-51 T 09-03-2017 IPR006286 Peptidase C56, PfpI ARZXY2_RS14485 6705c5e52b49d1da15e0ce7a6381f868 103 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.2E-20 T 09-03-2017 IPR009384 Flagellar ARZXY2_RS08645 4a39eecb2411f5c4e33efc8258d26b5f 235 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 235 46.889 T 09-03-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 ARZXY2_RS08645 4a39eecb2411f5c4e33efc8258d26b5f 235 Gene3D G3DSA:3.60.20.10 2 232 2.6E-72 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS08645 4a39eecb2411f5c4e33efc8258d26b5f 235 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 1 231 1.6E-111 T 09-03-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 ARZXY2_RS08645 4a39eecb2411f5c4e33efc8258d26b5f 235 SUPERFAMILY SSF56235 10 231 1.63E-40 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal ARZXY2_RS08645 4a39eecb2411f5c4e33efc8258d26b5f 235 Pfam PF00227 Proteasome subunit 25 204 4.4E-24 T 09-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 ARZXY2_RS00785 b9e17bb1cecb5289f9702fea19cfdc26 319 Gene3D G3DSA:3.40.50.720 143 266 3.4E-12 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00785 b9e17bb1cecb5289f9702fea19cfdc26 319 SUPERFAMILY SSF51735 137 267 3.67E-9 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00785 b9e17bb1cecb5289f9702fea19cfdc26 319 Gene3D G3DSA:3.40.192.10 7 142 4.8E-6 T 09-03-2017 ARZXY2_RS16600 2c7ee59e5d65edff153533eddb511dd2 235 SUPERFAMILY SSF48371 19 234 5.18E-62 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 ARZXY2_RS16600 2c7ee59e5d65edff153533eddb511dd2 235 Pfam PF08713 DNA alkylation repair enzyme 22 201 9.8E-22 T 09-03-2017 IPR014825 DNA alkylation repair enzyme ARZXY2_RS05675 3f2251852e9d9c36352050ef12ad1ac4 394 SUPERFAMILY SSF55874 285 391 3.01E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS05675 3f2251852e9d9c36352050ef12ad1ac4 394 Gene3D G3DSA:3.30.565.10 302 392 2.3E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS05675 3f2251852e9d9c36352050ef12ad1ac4 394 Pfam PF07730 Histidine kinase 190 255 1.4E-18 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 ARZXY2_RS15545 c48979c5651cdb3e9215be42c49b0d05 174 Pfam PF04191 Phospholipid methyltransferase 51 149 7.0E-14 T 09-03-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 ARZXY2_RS00715 0ff756860d77ea856c659be35d601027 303 PIRSF PIRSF009141 29 287 5.7E-92 T 09-03-2017 IPR008535 Protein of unknown function DUF817 ARZXY2_RS00715 0ff756860d77ea856c659be35d601027 303 Pfam PF05675 Protein of unknown function (DUF817) 38 274 3.6E-101 T 09-03-2017 IPR008535 Protein of unknown function DUF817 ARZXY2_RS12440 e62030c01faafe69e8b28f7e6052349c 475 Pfam PF01882 Protein of unknown function DUF58 282 360 2.8E-22 T 09-03-2017 IPR002881 Domain of unknown function DUF58 ARZXY2_RS04595 25c4cb5701841fbce0d4c7af7546c818 262 Pfam PF04012 PspA/IM30 family 5 235 2.6E-39 T 09-03-2017 IPR007157 PspA/IM30 ARZXY2_RS16555 026852a29c93dcb04c04f0c5653cee0d 188 Pfam PF03729 Short repeat of unknown function (DUF308) 20 84 6.2E-12 T 09-03-2017 IPR005325 Protein of unknown function DUF308, membrane ARZXY2_RS16555 026852a29c93dcb04c04f0c5653cee0d 188 Pfam PF03729 Short repeat of unknown function (DUF308) 131 181 3.7E-5 T 09-03-2017 IPR005325 Protein of unknown function DUF308, membrane ARZXY2_RS16555 026852a29c93dcb04c04f0c5653cee0d 188 Pfam PF03729 Short repeat of unknown function (DUF308) 76 144 8.9E-11 T 09-03-2017 IPR005325 Protein of unknown function DUF308, membrane ARZXY2_RS03080 443a512bbdbb454c2c427e9d06e517bd 130 Gene3D G3DSA:3.10.180.10 4 125 1.5E-31 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS03080 443a512bbdbb454c2c427e9d06e517bd 130 SUPERFAMILY SSF54593 3 126 1.48E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS03080 443a512bbdbb454c2c427e9d06e517bd 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 118 4.4E-9 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ARZXY2_RS18105 5a324bbe768bce98a883fd6a99af9dac 354 Pfam PF13692 Glycosyl transferases group 1 194 288 1.8E-8 T 09-03-2017 ARZXY2_RS18105 5a324bbe768bce98a883fd6a99af9dac 354 SUPERFAMILY SSF53756 205 323 6.67E-21 T 09-03-2017 ARZXY2_RS18105 5a324bbe768bce98a883fd6a99af9dac 354 Gene3D G3DSA:3.40.50.2000 184 301 6.6E-8 T 09-03-2017 ARZXY2_RS11730 4b5af568c0f98e82fd006ad24dd6551c 388 SUPERFAMILY SSF52518 44 374 1.2E-91 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS11730 4b5af568c0f98e82fd006ad24dd6551c 388 Gene3D G3DSA:3.40.50.970 31 371 5.1E-121 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS11730 4b5af568c0f98e82fd006ad24dd6551c 388 Pfam PF00676 Dehydrogenase E1 component 66 334 5.6E-75 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 ARZXY2_RS11730 4b5af568c0f98e82fd006ad24dd6551c 388 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 32 372 6.7E-134 T 09-03-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 ARZXY2_RS05275 893c0e85b1c9923173777681cb6f0e90 432 Pfam PF00756 Putative esterase 188 412 3.0E-21 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 ARZXY2_RS05275 893c0e85b1c9923173777681cb6f0e90 432 Gene3D G3DSA:3.40.50.1820 164 429 2.0E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS05275 893c0e85b1c9923173777681cb6f0e90 432 SUPERFAMILY SSF53474 175 428 1.31E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS04330 406e32662836742729a493db7f6130fd 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 1.0E-29 T 09-03-2017 IPR021465 Protein of unknown function DUF3117 ARZXY2_RS15020 93b924296f423986a561df453b50fb81 219 Pfam PF10759 Protein of unknown function (DUF2587) 47 196 6.1E-70 T 09-03-2017 IPR019695 Bacterial proteasome activator GO:0061136 ARZXY2_RS12855 54826fd949588c1f942ddce859206154 396 Pfam PF07314 Protein of unknown function (DUF1461) 156 336 5.1E-29 T 09-03-2017 IPR010178 Integral membrane protein 1906 ARZXY2_RS12855 54826fd949588c1f942ddce859206154 396 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 155 359 4.9E-26 T 09-03-2017 IPR010178 Integral membrane protein 1906 ARZXY2_RS20125 b0d87afac7b8b88d66f0d1f2dbbe0f77 157 Gene3D G3DSA:3.40.1000.10 49 154 3.6E-4 T 09-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 ARZXY2_RS11455 4a2eb31013fbb38ce55ee52ab9b25090 167 Pfam PF00994 Probable molybdopterin binding domain 15 155 2.8E-29 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11455 4a2eb31013fbb38ce55ee52ab9b25090 167 SMART SM00852 15 157 7.5E-23 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11455 4a2eb31013fbb38ce55ee52ab9b25090 167 Gene3D G3DSA:3.40.980.10 11 163 1.8E-50 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11455 4a2eb31013fbb38ce55ee52ab9b25090 167 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 149 2.7E-27 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS11455 4a2eb31013fbb38ce55ee52ab9b25090 167 SUPERFAMILY SSF53218 12 161 2.49E-41 T 09-03-2017 IPR001453 MoaB/Mog domain ARZXY2_RS05155 e9e99b4727069ee377a08f0f2e33b36a 159 SMART SM00900 80 158 0.0019 T 09-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 ARZXY2_RS05155 e9e99b4727069ee377a08f0f2e33b36a 159 Pfam PF04205 FMN-binding domain 83 153 2.1E-4 T 09-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 ARZXY2_RS18550 8486319edebd9921701eb00a26248a68 184 Pfam PF05258 Protein of unknown function (DUF721) 73 159 1.2E-24 T 09-03-2017 IPR007922 Protein of unknown function DUF721/UPF0232 ARZXY2_RS00755 2676689e83f038b7b603988ccf23df64 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 320 7.5E-52 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05885 0cc79bd84bd55ba638c1f65ac54a6786 215 Gene3D G3DSA:3.10.450.40 6 98 1.3E-8 T 09-03-2017 ARZXY2_RS05885 0cc79bd84bd55ba638c1f65ac54a6786 215 Pfam PF11523 Protein of unknown function (DUF3223) 23 95 1.7E-5 T 09-03-2017 IPR021602 Protein of unknown function DUF3223 ARZXY2_RS16040 d6d9a8f42a7cc097a45bb48cce2fc9da 427 SUPERFAMILY SSF103473 14 408 6.93E-58 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS16040 d6d9a8f42a7cc097a45bb48cce2fc9da 427 Gene3D G3DSA:1.20.1250.20 225 408 2.7E-13 T 09-03-2017 ARZXY2_RS16040 d6d9a8f42a7cc097a45bb48cce2fc9da 427 Gene3D G3DSA:1.20.1250.20 18 193 1.1E-23 T 09-03-2017 ARZXY2_RS16040 d6d9a8f42a7cc097a45bb48cce2fc9da 427 Pfam PF07690 Major Facilitator Superfamily 24 326 5.3E-29 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS05660 50c9f9e5b546a379f7a5c27ed276c99c 827 Pfam PF12704 MacB-like periplasmic core domain 21 223 1.2E-10 T 09-03-2017 IPR025857 MacB-like periplasmic core domain ARZXY2_RS05660 50c9f9e5b546a379f7a5c27ed276c99c 827 Pfam PF02687 FtsX-like permease family 704 820 2.2E-20 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS05660 50c9f9e5b546a379f7a5c27ed276c99c 827 Pfam PF02687 FtsX-like permease family 264 379 5.5E-17 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS00285 adde8cc89687f0c2a355c9460706ca3a 289 Pfam PF07751 Abi-like protein 72 223 8.3E-5 T 09-03-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like ARZXY2_RS15450 cd2be9a00f16a2cb42e35d93909ae380 207 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 129 185 6.4E-17 T 09-03-2017 ARZXY2_RS20230 c9c80f907856a43a3bccdcb9ef219add 253 Pfam PF01061 ABC-2 type transporter 11 216 3.5E-22 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS20230 c9c80f907856a43a3bccdcb9ef219add 253 PIRSF PIRSF006648 1 252 6.0E-63 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS16105 50e574c482b82355a1f6f8a1cfb02b72 383 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 226 321 1.5E-29 T 09-03-2017 IPR019236 Domain of unknown function DUF2183 ARZXY2_RS18045 1bef2653486d8fdbe03a6c5ac10ca5f2 199 Gene3D G3DSA:1.10.10.10 138 175 6.8E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS19330 59eb2f276d38242d310f64eef100207d 191 Gene3D G3DSA:1.10.357.10 5 186 9.8E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS19330 59eb2f276d38242d310f64eef100207d 191 SUPERFAMILY SSF46689 5 78 3.19E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS19330 59eb2f276d38242d310f64eef100207d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.2E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS19330 59eb2f276d38242d310f64eef100207d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.2E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS19330 59eb2f276d38242d310f64eef100207d 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 5.7E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS01845 794fee82b070277864a493db7228ccdd 78 Pfam PF14029 Protein of unknown function (DUF4244) 25 76 8.1E-21 T 09-03-2017 IPR025338 Protein of unknown function DUF4244 ARZXY2_RS10055 a33744f929aedfa752ca06ff095baec8 419 Gene3D G3DSA:1.50.10.10 1 393 2.9E-96 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS10055 a33744f929aedfa752ca06ff095baec8 419 SUPERFAMILY SSF48208 3 406 8.38E-117 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS10055 a33744f929aedfa752ca06ff095baec8 419 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 32 387 1.9E-116 T 09-03-2017 ARZXY2_RS04630 3bfffbe797e49d076b690c46cb59e397 285 Pfam PF10099 Anti-sigma-K factor rskA 80 279 1.6E-25 T 09-03-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 ARZXY2_RS18155 56fc2b2e99174b0a8f83beecad2d2032 352 SMART SM00046 49 169 0.0099 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS18155 56fc2b2e99174b0a8f83beecad2d2032 352 Pfam PF00781 Diacylglycerol kinase catalytic domain 50 170 7.5E-18 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 ARZXY2_RS18155 56fc2b2e99174b0a8f83beecad2d2032 352 Gene3D G3DSA:3.40.50.10330 93 161 1.6E-6 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 ARZXY2_RS18155 56fc2b2e99174b0a8f83beecad2d2032 352 SUPERFAMILY SSF111331 47 349 5.4E-66 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain ARZXY2_RS08615 79dcd6c3b92bbdaacb104a2476a8decd 89 Pfam PF02416 mttA/Hcf106 family 6 53 8.7E-15 T 09-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 ARZXY2_RS08615 79dcd6c3b92bbdaacb104a2476a8decd 89 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 81 17.598 T 09-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 27 3.5E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 Pfam PF13416 Bacterial extracellular solute-binding protein 59 352 2.5E-23 T 09-03-2017 ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 Gene3D G3DSA:3.40.190.10 152 323 3.6E-13 T 09-03-2017 ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 SUPERFAMILY SSF53850 22 426 5.67E-53 T 09-03-2017 ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 Gene3D G3DSA:3.40.190.10 9 146 5.3E-23 T 09-03-2017 ARZXY2_RS02030 162d11b2becb61a3a8b044e3fc93975f 428 Gene3D G3DSA:3.40.190.10 324 357 5.3E-23 T 09-03-2017 ARZXY2_RS03040 d0e0b28081d631e8b0897010957241cd 181 Pfam PF13279 Thioesterase-like superfamily 32 163 3.2E-22 T 09-03-2017 ARZXY2_RS03040 d0e0b28081d631e8b0897010957241cd 181 SUPERFAMILY SSF54637 25 164 3.74E-30 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS03040 d0e0b28081d631e8b0897010957241cd 181 Gene3D G3DSA:3.10.129.10 24 146 5.3E-24 T 09-03-2017 IPR029069 HotDog domain ARZXY2_RS19150 e97dc27525ab2b670646c79bfcb19223 80 Pfam PF01494 FAD binding domain 4 54 7.2E-11 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 ARZXY2_RS19150 e97dc27525ab2b670646c79bfcb19223 80 Gene3D G3DSA:3.50.50.60 1 51 1.9E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS19150 e97dc27525ab2b670646c79bfcb19223 80 SUPERFAMILY SSF51905 3 60 4.4E-13 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS05225 e6d6bed98444b0dd3ed82bc7c4474dd0 111 Gene3D G3DSA:1.20.1250.20 33 83 9.4E-5 T 09-03-2017 ARZXY2_RS13675 5f304831098e55ea72230d410cdde177 222 Pfam PF04854 Protein of unknown function, DUF624 46 108 1.1E-10 T 09-03-2017 IPR006938 Protein of unknown function DUF624 ARZXY2_RS02740 1e9325a9c2fc228bc4f33f2080d6510e 472 SUPERFAMILY SSF53850 45 241 2.69E-60 T 09-03-2017 ARZXY2_RS02740 1e9325a9c2fc228bc4f33f2080d6510e 472 SUPERFAMILY SSF53850 268 468 2.69E-60 T 09-03-2017 ARZXY2_RS02740 1e9325a9c2fc228bc4f33f2080d6510e 472 Pfam PF01547 Bacterial extracellular solute-binding protein 58 378 1.9E-27 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS02740 1e9325a9c2fc228bc4f33f2080d6510e 472 Gene3D G3DSA:3.40.190.10 180 397 7.4E-23 T 09-03-2017 ARZXY2_RS02740 1e9325a9c2fc228bc4f33f2080d6510e 472 Gene3D G3DSA:3.40.190.10 54 179 4.0E-16 T 09-03-2017 ARZXY2_RS09000 f83d5d842132a984301ef67ddcbb772e 491 SUPERFAMILY SSF101960 57 488 2.75E-142 T 09-03-2017 ARZXY2_RS09000 f83d5d842132a984301ef67ddcbb772e 491 Pfam PF01458 Uncharacterized protein family (UPF0051) 237 462 1.1E-76 T 09-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 ARZXY2_RS09000 f83d5d842132a984301ef67ddcbb772e 491 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 35 482 3.5E-221 T 09-03-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 ARZXY2_RS01620 4e871e6b700af3340023629912f47301 311 Gene3D G3DSA:3.30.465.10 53 172 2.0E-22 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 ARZXY2_RS01620 4e871e6b700af3340023629912f47301 311 SUPERFAMILY SSF56176 2 173 8.18E-28 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 ARZXY2_RS01620 4e871e6b700af3340023629912f47301 311 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 25 173 7.3E-17 T 09-03-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 ARZXY2_RS09450 b3e79a6856db15df28a73eabe64c663b 132 Gene3D G3DSA:3.30.1330.40 1 130 1.2E-34 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS09450 b3e79a6856db15df28a73eabe64c663b 132 SUPERFAMILY SSF55298 1 130 1.01E-31 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like ARZXY2_RS09450 b3e79a6856db15df28a73eabe64c663b 132 Pfam PF01042 Endoribonuclease L-PSP 16 128 2.1E-21 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family ARZXY2_RS14070 21b016d813c71e5d2d68b1cb23256030 305 Pfam PF01261 Xylose isomerase-like TIM barrel 34 222 2.8E-21 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14070 21b016d813c71e5d2d68b1cb23256030 305 SUPERFAMILY SSF51658 7 278 4.15E-41 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS14070 21b016d813c71e5d2d68b1cb23256030 305 Gene3D G3DSA:3.20.20.150 9 299 3.9E-56 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS02520 4ea155ad1aa2b3bb5b5b9063fa2bcd70 266 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 238 1.5E-44 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ARZXY2_RS02520 4ea155ad1aa2b3bb5b5b9063fa2bcd70 266 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 61 240 1.4E-29 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ARZXY2_RS11360 1fe267923d6a83876ad9af654093ca8f 204 Pfam PF05175 Methyltransferase small domain 31 185 2.3E-29 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 ARZXY2_RS11360 1fe267923d6a83876ad9af654093ca8f 204 Gene3D G3DSA:3.40.50.150 29 178 1.0E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS11360 1fe267923d6a83876ad9af654093ca8f 204 SUPERFAMILY SSF53335 18 176 4.29E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS18655 acdf6f9936750fdce3d4b23b5592d725 201 Pfam PF13460 NAD(P)H-binding 7 190 5.4E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18655 acdf6f9936750fdce3d4b23b5592d725 201 SUPERFAMILY SSF51735 1 199 3.77E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18655 acdf6f9936750fdce3d4b23b5592d725 201 Gene3D G3DSA:3.40.50.720 1 200 2.5E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS03890 730bf4034fea3e2ba0bb50f95b91e107 685 Pfam PF01757 Acyltransferase family 17 355 5.0E-13 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 ARZXY2_RS13830 3df320a5a6e32a92930be1cf63c96aed 356 SUPERFAMILY SSF51395 1 355 3.89E-113 T 09-03-2017 ARZXY2_RS13830 3df320a5a6e32a92930be1cf63c96aed 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 333 5.4E-79 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS13830 3df320a5a6e32a92930be1cf63c96aed 356 Gene3D G3DSA:3.20.20.70 2 354 5.9E-117 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 ARZXY2_RS12250 fa98d14cbb9387107ab854c78ad11f61 212 Pfam PF13468 Glyoxalase-like domain 3 174 2.6E-32 T 09-03-2017 IPR025870 Glyoxalase-like domain ARZXY2_RS00700 d2958dbb2060dcc6ac6f299fba26a74b 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 207 5.0E-19 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS00700 d2958dbb2060dcc6ac6f299fba26a74b 309 SUPERFAMILY SSF51735 2 304 2.45E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS00700 d2958dbb2060dcc6ac6f299fba26a74b 309 Gene3D G3DSA:3.40.50.720 3 299 7.5E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS08410 19c7c8df17589803a9ca4c1f937e8114 356 SUPERFAMILY SSF50022 187 348 1.05E-29 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS08410 19c7c8df17589803a9ca4c1f937e8114 356 Gene3D G3DSA:2.102.10.10 156 349 5.6E-41 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS08410 19c7c8df17589803a9ca4c1f937e8114 356 Pfam PF00355 Rieske [2Fe-2S] domain 266 321 2.5E-11 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 ARZXY2_RS10655 1a42eef8e6cdc1f296830414a9478a07 439 Pfam PF13830 Domain of unknown function (DUF4192) 368 418 1.8E-12 T 09-03-2017 IPR025447 Protein of unknown function DUF4192 ARZXY2_RS10655 1a42eef8e6cdc1f296830414a9478a07 439 Pfam PF13830 Domain of unknown function (DUF4192) 14 273 2.1E-28 T 09-03-2017 IPR025447 Protein of unknown function DUF4192 ARZXY2_RS18490 0f8c9e6c87709d3bded0afcd22ac051b 210 SUPERFAMILY SSF55136 118 200 2.88E-9 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS18490 0f8c9e6c87709d3bded0afcd22ac051b 210 Gene3D G3DSA:3.20.80.10 6 207 3.1E-75 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain ARZXY2_RS18490 0f8c9e6c87709d3bded0afcd22ac051b 210 PIRSF PIRSF031644 6 210 1.4E-62 T 09-03-2017 IPR008319 Uncharacterised conserved protein UCP031644 ARZXY2_RS18490 0f8c9e6c87709d3bded0afcd22ac051b 210 Pfam PF06445 GyrI-like small molecule binding domain 26 205 1.8E-25 T 09-03-2017 IPR029442 GyrI-like small molecule binding domain ARZXY2_RS06380 c110314ad051a5a8b261e3d3d7979a6d 274 Pfam PF02517 CAAX protease self-immunity 125 211 2.1E-18 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 ARZXY2_RS15525 168014d835e35f116b647e831adb3115 235 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 27 225 2.7E-27 T 09-03-2017 IPR003744 Protein of unknown function DUF165 ARZXY2_RS15525 168014d835e35f116b647e831adb3115 235 Pfam PF02592 Putative vitamin uptake transporter 55 219 6.7E-44 T 09-03-2017 IPR003744 Protein of unknown function DUF165 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 7.2E-16 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 7.2E-16 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 126 151 7.2E-16 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 163 187 7.2E-16 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 219 238 7.2E-16 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 Pfam PF01061 ABC-2 type transporter 28 240 8.4E-17 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS13265 a7adeab7e58efd1e05b422791d50975a 277 PIRSF PIRSF006648 8 275 1.7E-17 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS13120 a066174f0a7a088043ac20cb7e7af69b 249 Pfam PF04977 Septum formation initiator 134 206 2.2E-15 T 09-03-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 ARZXY2_RS08975 06edca852c3ab8ef266f56a4b7c7da9d 299 Pfam PF04228 Putative neutral zinc metallopeptidase 12 294 3.1E-72 T 09-03-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative ARZXY2_RS08975 06edca852c3ab8ef266f56a4b7c7da9d 299 SUPERFAMILY SSF55486 105 290 6.81E-11 T 09-03-2017 ARZXY2_RS15160 af21c3d84b4c1928be7a3fe7e94a81bb 322 Gene3D G3DSA:3.30.420.40 2 141 1.8E-38 T 09-03-2017 ARZXY2_RS15160 af21c3d84b4c1928be7a3fe7e94a81bb 322 SUPERFAMILY SSF53067 1 321 9.98E-48 T 09-03-2017 ARZXY2_RS15160 af21c3d84b4c1928be7a3fe7e94a81bb 322 Gene3D G3DSA:3.30.420.40 142 304 5.8E-33 T 09-03-2017 ARZXY2_RS15160 af21c3d84b4c1928be7a3fe7e94a81bb 322 Pfam PF00480 ROK family 5 321 5.2E-51 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 ARZXY2_RS05545 03bf2cff219f377bf2b3a795e6d01d19 400 PRINTS PR00758 Arsenical pump membrane protein signature 83 107 7.5E-16 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 ARZXY2_RS05545 03bf2cff219f377bf2b3a795e6d01d19 400 PRINTS PR00758 Arsenical pump membrane protein signature 157 180 7.5E-16 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 ARZXY2_RS05545 03bf2cff219f377bf2b3a795e6d01d19 400 PRINTS PR00758 Arsenical pump membrane protein signature 369 393 7.5E-16 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 ARZXY2_RS05545 03bf2cff219f377bf2b3a795e6d01d19 400 PRINTS PR00758 Arsenical pump membrane protein signature 336 361 7.5E-16 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 ARZXY2_RS05545 03bf2cff219f377bf2b3a795e6d01d19 400 Pfam PF02040 Arsenical pump membrane protein 11 391 1.7E-20 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 ARZXY2_RS08685 5272aaae50ad75a00f928bee3b6c1524 301 PIRSF PIRSF028754 20 301 3.8E-90 T 09-03-2017 IPR008492 Protein of unknown function DUF774 ARZXY2_RS08685 5272aaae50ad75a00f928bee3b6c1524 301 SUPERFAMILY SSF159659 31 278 6.54E-79 T 09-03-2017 ARZXY2_RS08685 5272aaae50ad75a00f928bee3b6c1524 301 Pfam PF09754 PAC2 family 37 255 3.4E-43 T 09-03-2017 IPR019151 Proteasome assembly chaperone 2 ARZXY2_RS11790 9d9f79290c8d043d65c6c8227da9e6c7 311 Pfam PF01148 Cytidylyltransferase family 41 307 1.2E-53 T 09-03-2017 ARZXY2_RS11790 9d9f79290c8d043d65c6c8227da9e6c7 311 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 266 292 - T 09-03-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 ARZXY2_RS12195 64f7c33023f15454925f2be0b699cdbf 320 SUPERFAMILY SSF55729 3 137 6.76E-11 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS12195 64f7c33023f15454925f2be0b699cdbf 320 Gene3D G3DSA:3.40.630.30 3 138 9.9E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase ARZXY2_RS08235 4f36c42057d55e89d25320e36132a4da 602 Pfam PF13567 Domain of unknown function (DUF4131) 40 191 1.8E-9 T 09-03-2017 IPR025405 Domain of unknown function DUF4131 ARZXY2_RS08235 4f36c42057d55e89d25320e36132a4da 602 Pfam PF03772 Competence protein 244 507 9.6E-41 T 09-03-2017 IPR004477 ComEC/Rec2-related protein ARZXY2_RS08235 4f36c42057d55e89d25320e36132a4da 602 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 266 429 1.0E-19 T 09-03-2017 IPR004477 ComEC/Rec2-related protein ARZXY2_RS16825 5bea0d4a1c8ec536ceba7278c6e5a79d 280 Gene3D G3DSA:3.40.50.150 19 274 2.8E-64 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS16825 5bea0d4a1c8ec536ceba7278c6e5a79d 280 SUPERFAMILY SSF53335 30 243 4.8E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS15770 a41606b8973e7a0691ce8dcac718c94c 309 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 49 261 1.9E-44 T 09-03-2017 IPR018713 Domain of unknown function DUF2236 ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 249 268 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 24 440 2.0E-169 T 09-03-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 Gene3D G3DSA:3.40.640.10 54 316 5.6E-83 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 Pfam PF00266 Aminotransferase class-V 42 428 1.9E-133 T 09-03-2017 IPR000192 Aminotransferase class V domain ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 Gene3D G3DSA:3.90.1150.10 317 433 3.3E-25 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 ARZXY2_RS12740 b16446f080ad120dec2b882aaed895a7 441 SUPERFAMILY SSF53383 22 434 4.34E-119 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase ARZXY2_RS13355 0ab396ac9a4441e3e41bc10611bbfb05 393 Pfam PF02687 FtsX-like permease family 270 384 1.1E-13 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS13355 0ab396ac9a4441e3e41bc10611bbfb05 393 Pfam PF12704 MacB-like periplasmic core domain 23 202 8.1E-12 T 09-03-2017 IPR025857 MacB-like periplasmic core domain ARZXY2_RS14215 f5d87208e8497e783e9ff31789e850a6 295 Gene3D G3DSA:3.90.550.10 1 190 2.1E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS14215 f5d87208e8497e783e9ff31789e850a6 295 Pfam PF12804 MobA-like NTP transferase domain 5 154 8.3E-26 T 09-03-2017 IPR025877 MobA-like NTP transferase ARZXY2_RS14215 f5d87208e8497e783e9ff31789e850a6 295 SUPERFAMILY SSF53448 1 187 3.83E-25 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS15715 140381c0f417ff3b46fae4f0bab6aab9 297 SUPERFAMILY SSF161098 24 293 4.58E-69 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15715 140381c0f417ff3b46fae4f0bab6aab9 297 Gene3D G3DSA:1.10.3720.10 20 283 2.4E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS15715 140381c0f417ff3b46fae4f0bab6aab9 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 288 7.3E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS20565 2457b6c09b84b4490fb7c52ddea3590b 164 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 2.7E-58 T 09-03-2017 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger ARZXY2_RS09270 b6e2aa661cf4f61ce3fec0eefb45de2e 341 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 19 264 1.5E-69 T 09-03-2017 IPR014145 DNA ligase D, polymerase domain ARZXY2_RS12990 b29594b11f40ea3af40b2070eed02057 213 Pfam PF03006 Haemolysin-III related 8 204 1.5E-34 T 09-03-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 ARZXY2_RS03140 4e95aae139099be82b3dc4dff4b47d42 402 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 384 1.3E-138 T 09-03-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain ARZXY2_RS03140 4e95aae139099be82b3dc4dff4b47d42 402 SUPERFAMILY SSF56059 2 166 8.83E-67 T 09-03-2017 ARZXY2_RS03140 4e95aae139099be82b3dc4dff4b47d42 402 SUPERFAMILY SSF56059 269 382 8.83E-67 T 09-03-2017 ARZXY2_RS03140 4e95aae139099be82b3dc4dff4b47d42 402 SUPERFAMILY SSF52440 173 282 1.78E-35 T 09-03-2017 IPR016185 Pre-ATP-grasp domain ARZXY2_RS19750 da025508baa0a89534571a3023d15ed8 181 SUPERFAMILY SSF47226 37 152 3.66E-12 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS19750 da025508baa0a89534571a3023d15ed8 181 Gene3D G3DSA:1.20.120.160 42 147 3.7E-10 T 09-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 ARZXY2_RS08515 ecc41a992017a37fbe3025bf69702343 494 SUPERFAMILY SSF56349 231 429 2.44E-10 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 ARZXY2_RS08515 ecc41a992017a37fbe3025bf69702343 494 Gene3D G3DSA:1.10.443.10 314 428 7.2E-6 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 ARZXY2_RS09335 badedbce7b9022c7510daefbfbd022a9 119 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 83 116 1.2E-13 T 09-03-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 ARZXY2_RS09335 badedbce7b9022c7510daefbfbd022a9 119 SUPERFAMILY SSF109635 4 84 4.18E-7 T 09-03-2017 ARZXY2_RS09335 badedbce7b9022c7510daefbfbd022a9 119 SUPERFAMILY SSF57716 85 114 1.28E-6 T 09-03-2017 ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 Gene3D G3DSA:3.40.50.720 3 152 3.9E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 SUPERFAMILY SSF55347 138 297 9.32E-12 T 09-03-2017 ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 3 337 46.465 T 09-03-2017 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 114 1.3E-21 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 SUPERFAMILY SSF51735 3 154 8.47E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS14065 386176c8fb5767ed425c278102703b88 337 Gene3D G3DSA:3.30.360.10 153 264 1.6E-32 T 09-03-2017 ARZXY2_RS18670 8ec6e4e5e5108d8507d1e3b49b193ec5 357 Pfam PF02687 FtsX-like permease family 243 350 2.0E-9 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 ARZXY2_RS01110 8b02d2a84862ccb8b7bc2a0fa37af956 155 Pfam PF14325 Domain of unknown function (DUF4383) 15 138 1.0E-48 T 09-03-2017 IPR025492 Protein of unknown function DUF4383 ARZXY2_RS03745 0fc6f055bf9b47826488e2e4236352ff 279 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 124 251 4.6E-34 T 09-03-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 ARZXY2_RS03745 0fc6f055bf9b47826488e2e4236352ff 279 SUPERFAMILY SSF55166 121 258 7.06E-31 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 ARZXY2_RS15650 03b5baff2db325d1e597fa96bf965303 330 Pfam PF03601 Conserved hypothetical protein 698 5 311 1.6E-62 T 09-03-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 ARZXY2_RS03725 0744e010d8b565d6fdf16e8868045d1c 214 Pfam PF01478 Type IV leader peptidase family 71 181 2.7E-10 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 ARZXY2_RS12885 603d0afb485783db5ebced6e6513cbf8 125 Pfam PF12005 Protein of unknown function (DUF3499) 4 123 2.4E-47 T 09-03-2017 IPR021888 Protein of unknown function DUF3499 ARZXY2_RS17110 febe9962a4144f39d355be0d43d8ad73 256 Pfam PF02517 CAAX protease self-immunity 146 237 3.7E-5 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 ARZXY2_RS00665 a5c483bd7b52f1e2d2d0c303909f64a8 444 Pfam PF04984 Phage tail sheath protein 1 93 9.9E-8 T 09-03-2017 IPR007067 Tail sheath protein ARZXY2_RS00665 a5c483bd7b52f1e2d2d0c303909f64a8 444 Pfam PF04984 Phage tail sheath protein 109 428 5.9E-51 T 09-03-2017 IPR007067 Tail sheath protein ARZXY2_RS08350 4ecdd027061b7eb9a0cfbcae2e7fa306 338 Gene3D G3DSA:3.40.50.1820 47 322 5.9E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08350 4ecdd027061b7eb9a0cfbcae2e7fa306 338 SUPERFAMILY SSF53474 30 323 4.53E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS08350 4ecdd027061b7eb9a0cfbcae2e7fa306 338 Pfam PF12146 Serine aminopeptidase, S33 49 256 9.8E-21 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 ARZXY2_RS12150 8ed5ef17cd9caf5da911e80000991b57 842 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 493 802 1.8E-93 T 09-03-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal ARZXY2_RS12150 8ed5ef17cd9caf5da911e80000991b57 842 SUPERFAMILY SSF144091 18 203 3.27E-10 T 09-03-2017 ARZXY2_RS03240 92b6a7bf79d76ac17cd66d9d2ba49263 74 Pfam PF11384 Protein of unknown function (DUF3188) 19 70 4.9E-11 T 09-03-2017 IPR021524 Protein of unknown function DUF3188 ARZXY2_RS18820 8cac355a2a1cc1286cf87ba0f37b87cf 149 SUPERFAMILY SSF55961 3 139 6.77E-16 T 09-03-2017 ARZXY2_RS18820 8cac355a2a1cc1286cf87ba0f37b87cf 149 Gene3D G3DSA:3.30.530.20 5 137 8.5E-6 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS04560 555193eef8d840703fa6bd74ee5eca83 188 Pfam PF01863 Protein of unknown function DUF45 106 171 3.5E-20 T 09-03-2017 IPR002725 Protein of unknown function DUF45 ARZXY2_RS08935 2c965c27661ef67f2ca6babfba8a14b4 288 Pfam PF02104 SURF1 family 19 223 5.2E-28 T 09-03-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 ARZXY2_RS10140 021d3a5b8bf61f56b4c3fa71a999b317 293 Pfam PF02012 BNR/Asp-box repeat 196 206 0.018 T 09-03-2017 IPR002860 BNR repeat ARZXY2_RS10140 021d3a5b8bf61f56b4c3fa71a999b317 293 Pfam PF02012 BNR/Asp-box repeat 122 130 0.11 T 09-03-2017 IPR002860 BNR repeat ARZXY2_RS10140 021d3a5b8bf61f56b4c3fa71a999b317 293 Gene3D G3DSA:2.130.10.140 50 292 1.5E-23 T 09-03-2017 ARZXY2_RS10140 021d3a5b8bf61f56b4c3fa71a999b317 293 SUPERFAMILY SSF110296 48 291 6.28E-30 T 09-03-2017 ARZXY2_RS13010 ce83dfe4df39602ab54254fad90d6e16 152 Pfam PF14155 Domain of unknown function (DUF4307) 30 145 9.1E-26 T 09-03-2017 IPR025443 Protein of unknown function DUF4307 ARZXY2_RS03375 0d0701b609f06b817fcbb08b4657f7bb 424 Pfam PF04024 PspC domain 2 39 3.9E-7 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal ARZXY2_RS15570 3d7325ca8b38ee7b89d5f4437cdc10d2 281 Pfam PF08543 Phosphomethylpyrimidine kinase 22 268 6.3E-59 T 09-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 ARZXY2_RS15570 3d7325ca8b38ee7b89d5f4437cdc10d2 281 SUPERFAMILY SSF53613 12 268 2.03E-53 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS15570 3d7325ca8b38ee7b89d5f4437cdc10d2 281 Gene3D G3DSA:3.40.1190.20 12 268 1.3E-66 T 09-03-2017 IPR029056 Ribokinase-like ARZXY2_RS07250 8f277e6b21a1894d2594411695aba7b9 112 Pfam PF02656 Domain of unknown function (DUF202) 6 70 4.6E-13 T 09-03-2017 IPR003807 Domain of unknown function DUF202 ARZXY2_RS07250 8f277e6b21a1894d2594411695aba7b9 112 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 6 34 0.002 T 09-03-2017 IPR020264 Uncharacterised protein family YidG ARZXY2_RS08925 5ae62aa19f965426b274f2958fd87e45 164 Pfam PF11298 Protein of unknown function (DUF3099) 33 97 1.1E-24 T 09-03-2017 IPR021449 Protein of unknown function DUF3099 ARZXY2_RS02765 0b0c35805b963f43a50860f2381274ff 205 Pfam PF10708 Protein of unknown function (DUF2510) 12 42 6.1E-13 T 09-03-2017 IPR018929 Domain of unknown function DUF2510 ARZXY2_RS17640 f0aac80b73812911a299f4def8416c9e 340 Pfam PF01384 Phosphate transporter family 173 325 8.7E-34 T 09-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 ARZXY2_RS17640 f0aac80b73812911a299f4def8416c9e 340 Pfam PF01384 Phosphate transporter family 20 164 9.9E-26 T 09-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 ARZXY2_RS14675 740167b7c6852c600081c5890a5e7ac6 163 Pfam PF05656 Protein of unknown function (DUF805) 41 158 2.7E-29 T 09-03-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 ARZXY2_RS02880 b0b5ae561b9c26aed1ca7e73d43e6091 312 Gene3D G3DSA:1.10.3720.10 56 303 4.2E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02880 b0b5ae561b9c26aed1ca7e73d43e6091 312 SUPERFAMILY SSF161098 102 290 1.7E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS02880 b0b5ae561b9c26aed1ca7e73d43e6091 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 292 8.5E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS14130 f183f258fb3b8b27f3399e82d10338f7 261 Pfam PF06197 Protein of unknown function (DUF998) 40 109 4.2E-9 T 09-03-2017 IPR009339 Protein of unknown function DUF998 ARZXY2_RS19925 caa32a15590211dd5212224266a15b35 224 Pfam PF03737 Demethylmenaquinone methyltransferase 25 172 1.4E-32 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS19925 caa32a15590211dd5212224266a15b35 224 SUPERFAMILY SSF89562 21 182 5.49E-42 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS19925 caa32a15590211dd5212224266a15b35 224 Gene3D G3DSA:3.50.30.40 21 181 2.1E-43 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein ARZXY2_RS00175 a59263aa7e57818c6d0ef8c0c318030c 308 Pfam PF03547 Membrane transport protein 160 301 1.5E-15 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ARZXY2_RS00175 a59263aa7e57818c6d0ef8c0c318030c 308 Pfam PF03547 Membrane transport protein 11 141 4.2E-11 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 ARZXY2_RS05905 b84e904377f5b99eaa2d2743cac00e6a 269 Pfam PF08378 Nuclease-related domain 107 215 1.0E-13 T 09-03-2017 IPR011528 Nuclease-related domain, NERD ARZXY2_RS14040 6d5e01cc89421b0522ee746c71589cd8 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 338 6.0E-54 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS08265 e594ab52e1673e7adca8a2c308b8c97f 137 Pfam PF09685 Domain of unknown function (DUF4870) 33 136 4.6E-21 T 09-03-2017 IPR019109 Protein of unknown function DUF4870 ARZXY2_RS20330 7efe031c461ab80d91ee0d5223e7af69 488 Pfam PF13556 PucR C-terminal helix-turn-helix domain 427 484 1.9E-14 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS20330 7efe031c461ab80d91ee0d5223e7af69 488 Pfam PF07905 Purine catabolism regulatory protein-like family 9 129 8.2E-28 T 09-03-2017 IPR012914 Purine catabolism PurC-like domain ARZXY2_RS13705 5d159102007c8051cbd95858978e4ed7 94 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 09-03-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 ARZXY2_RS13705 5d159102007c8051cbd95858978e4ed7 94 Pfam PF00708 Acylphosphatase 6 92 3.9E-24 T 09-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 ARZXY2_RS13705 5d159102007c8051cbd95858978e4ed7 94 SUPERFAMILY SSF54975 4 93 7.63E-25 T 09-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 ARZXY2_RS13705 5d159102007c8051cbd95858978e4ed7 94 Gene3D G3DSA:3.30.70.100 6 92 4.9E-27 T 09-03-2017 ARZXY2_RS03685 cdbb1ec14a9d45fecaf6c128f02c33b4 292 Pfam PF00482 Type II secretion system (T2SS), protein F 155 280 5.6E-19 T 09-03-2017 IPR018076 Type II secretion system F domain ARZXY2_RS06990 5f2a4713d9f27408cfc6820f5e02f725 360 Gene3D G3DSA:3.20.20.140 51 320 2.5E-60 T 09-03-2017 ARZXY2_RS06990 5f2a4713d9f27408cfc6820f5e02f725 360 Pfam PF01979 Amidohydrolase family 45 358 3.8E-15 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 ARZXY2_RS06990 5f2a4713d9f27408cfc6820f5e02f725 360 SUPERFAMILY SSF51556 49 323 6.5E-59 T 09-03-2017 IPR032466 Metal-dependent hydrolase ARZXY2_RS06990 5f2a4713d9f27408cfc6820f5e02f725 360 Gene3D G3DSA:2.30.40.10 322 359 3.3E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS06990 5f2a4713d9f27408cfc6820f5e02f725 360 Gene3D G3DSA:2.30.40.10 45 50 3.3E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 ARZXY2_RS01900 ad0eab1689eda1032f98b6b6ae9ff3e1 144 Pfam PF07179 SseB protein N-terminal domain 17 127 6.1E-14 T 09-03-2017 IPR009839 SseB protein N-terminal domain ARZXY2_RS02110 571df0964732a0a858a5b0bd97e0f261 103 Pfam PF04480 Protein of unknown function (DUF559) 28 87 2.1E-6 T 09-03-2017 IPR007569 Domain of unknown function DUF559 ARZXY2_RS02110 571df0964732a0a858a5b0bd97e0f261 103 SUPERFAMILY SSF52980 22 95 4.93E-6 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS07100 59266025c8b5eef72f3bb41172e3d009 551 SUPERFAMILY SSF52540 232 402 1.5E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS07100 59266025c8b5eef72f3bb41172e3d009 551 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 209 485 5.4E-41 T 09-03-2017 IPR006500 DNA primase, phage/plasmid ARZXY2_RS07100 59266025c8b5eef72f3bb41172e3d009 551 Gene3D G3DSA:3.40.50.300 241 386 7.3E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS18860 14609d80b52162e03b5febdfc2c8ec65 123 Pfam PF06993 Protein of unknown function (DUF1304) 16 119 8.6E-20 T 09-03-2017 IPR009732 Protein of unknown function DUF1304 ARZXY2_RS10525 1add9e192ca92c6596546fc73a586cfa 658 Pfam PF13520 Amino acid permease 66 465 2.3E-23 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 ARZXY2_RS13730 c456f41e3977b7ec1f0e147e35a054c2 480 Pfam PF13556 PucR C-terminal helix-turn-helix domain 417 474 2.9E-21 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS13730 c456f41e3977b7ec1f0e147e35a054c2 480 Pfam PF07905 Purine catabolism regulatory protein-like family 5 123 5.4E-21 T 09-03-2017 IPR012914 Purine catabolism PurC-like domain ARZXY2_RS05295 2b3cd9eddc5fe039212533e26c44ce18 231 Pfam PF01939 Protein of unknown function DUF91 1 231 4.2E-76 T 09-03-2017 IPR002793 Endonuclease NucS ARZXY2_RS05295 2b3cd9eddc5fe039212533e26c44ce18 231 Hamap MF_00722 Endonuclease NucS [nucS]. 1 223 32.471 T 09-03-2017 IPR002793 Endonuclease NucS ARZXY2_RS19220 b2180be576b7013a5d2fd99155385ef0 234 Pfam PF00857 Isochorismatase family 30 203 6.4E-30 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS19220 b2180be576b7013a5d2fd99155385ef0 234 SUPERFAMILY SSF52499 16 231 5.76E-44 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS19220 b2180be576b7013a5d2fd99155385ef0 234 Gene3D G3DSA:3.40.50.850 21 231 3.4E-50 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 ARZXY2_RS08755 1346ad613a584225b424ac8ec4765512 426 Gene3D G3DSA:3.40.50.2000 167 342 4.8E-7 T 09-03-2017 ARZXY2_RS08755 1346ad613a584225b424ac8ec4765512 426 SUPERFAMILY SSF53756 1 365 1.05E-32 T 09-03-2017 ARZXY2_RS08755 1346ad613a584225b424ac8ec4765512 426 Pfam PF13692 Glycosyl transferases group 1 184 289 3.7E-8 T 09-03-2017 ARZXY2_RS17475 3381dc880acb5ca2369cc8fce48e8a5c 412 Gene3D G3DSA:3.50.50.60 272 354 1.7E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17475 3381dc880acb5ca2369cc8fce48e8a5c 412 Gene3D G3DSA:3.50.50.60 5 170 1.7E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17475 3381dc880acb5ca2369cc8fce48e8a5c 412 SUPERFAMILY SSF51905 4 160 2.43E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS17475 3381dc880acb5ca2369cc8fce48e8a5c 412 SUPERFAMILY SSF51905 282 381 2.43E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS16665 3231f83b0e3fb2105689be47007f04bd 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 286 1.1E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16665 3231f83b0e3fb2105689be47007f04bd 293 Gene3D G3DSA:1.10.3720.10 28 280 7.3E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16665 3231f83b0e3fb2105689be47007f04bd 293 SUPERFAMILY SSF161098 27 292 1.31E-67 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS05045 6abdf5401f2c3ab3370f166b878e4aa4 282 Pfam PF13349 Putative adhesin 57 228 1.2E-7 T 09-03-2017 IPR025164 Putative adhesin ARZXY2_RS18890 52c9904af66c12c97deb5de21e7f3d76 296 Gene3D G3DSA:3.40.50.970 16 287 2.1E-77 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS18890 52c9904af66c12c97deb5de21e7f3d76 296 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 25 286 4.3E-39 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 ARZXY2_RS18890 52c9904af66c12c97deb5de21e7f3d76 296 SUPERFAMILY SSF52518 19 287 1.64E-67 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold ARZXY2_RS05080 56e6f01717955d0bfce0c8771b0003dd 296 Gene3D G3DSA:1.10.3470.10 27 258 5.5E-6 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS05080 56e6f01717955d0bfce0c8771b0003dd 296 Pfam PF00950 ABC 3 transport family 22 271 2.1E-44 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 ARZXY2_RS05080 56e6f01717955d0bfce0c8771b0003dd 296 SUPERFAMILY SSF81345 10 270 1.44E-32 T 09-03-2017 IPR029022 ABC transporter, BtuC-like ARZXY2_RS08270 7e53d82336f599c14f19e1a7f820d443 283 Pfam PF11296 Protein of unknown function (DUF3097) 15 281 1.1E-116 T 09-03-2017 IPR021447 Protein of unknown function DUF3097 ARZXY2_RS19945 32d480cdaa9253722af3e5cf3246d29a 259 SUPERFAMILY SSF88713 2 250 6.67E-87 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 ARZXY2_RS19945 32d480cdaa9253722af3e5cf3246d29a 259 Pfam PF03746 LamB/YcsF family 2 238 1.6E-88 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF ARZXY2_RS09020 25f54a68c9d66b78db8c997491b4fe01 314 Pfam PF02628 Cytochrome oxidase assembly protein 27 300 2.5E-24 T 09-03-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 ARZXY2_RS14900 0f97c2e5d9de4184138e4747c2859324 160 SUPERFAMILY SSF141259 3 66 1.96E-13 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS14900 0f97c2e5d9de4184138e4747c2859324 160 SMART SM01058 2 112 2.1E-32 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS14900 0f97c2e5d9de4184138e4747c2859324 160 Pfam PF02559 CarD-like/TRCF domain 3 110 8.8E-15 T 09-03-2017 IPR003711 CarD-like/TRCF domain ARZXY2_RS11310 8a77cb11141ad29b01468ed0c619d5c0 436 Gene3D G3DSA:1.20.1250.20 12 193 9.5E-11 T 09-03-2017 ARZXY2_RS11310 8a77cb11141ad29b01468ed0c619d5c0 436 Pfam PF07690 Major Facilitator Superfamily 288 430 8.8E-12 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 ARZXY2_RS11310 8a77cb11141ad29b01468ed0c619d5c0 436 Gene3D G3DSA:1.20.1250.20 253 430 3.9E-15 T 09-03-2017 ARZXY2_RS11310 8a77cb11141ad29b01468ed0c619d5c0 436 SUPERFAMILY SSF103473 13 429 1.05E-29 T 09-03-2017 IPR020846 Major facilitator superfamily domain ARZXY2_RS19730 948e58e6084865b9f47bb6516b2c33d8 86 Pfam PF04226 Transglycosylase associated protein 34 83 1.5E-8 T 09-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 ARZXY2_RS18945 cf3ffff3ec4e8040db47e96c96c1a3d7 87 SUPERFAMILY SSF140453 6 85 9.42E-6 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS18945 cf3ffff3ec4e8040db47e96c96c1a3d7 87 Pfam PF06013 Proteins of 100 residues with WXG 6 85 2.2E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS18945 cf3ffff3ec4e8040db47e96c96c1a3d7 87 Gene3D G3DSA:1.10.287.850 6 80 2.0E-4 T 09-03-2017 IPR029013 HP0062-like domain ARZXY2_RS20525 bbe7cd15698d5676b14399dc62281521 163 Pfam PF01613 Flavin reductase like domain 17 161 1.9E-27 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS20525 bbe7cd15698d5676b14399dc62281521 163 SUPERFAMILY SSF50475 10 160 2.4E-35 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS20525 bbe7cd15698d5676b14399dc62281521 163 Gene3D G3DSA:2.30.110.10 8 160 1.2E-42 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 ARZXY2_RS20525 bbe7cd15698d5676b14399dc62281521 163 SMART SM00903 16 160 6.7E-43 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 ARZXY2_RS07255 e3308f6e1886f7e54eb4fa5df4f5a2a6 121 Pfam PF02656 Domain of unknown function (DUF202) 21 86 1.6E-11 T 09-03-2017 IPR003807 Domain of unknown function DUF202 ARZXY2_RS16750 ae8d9d3ee1792c2d3da112f0a8f056a8 212 SUPERFAMILY SSF81296 30 122 8.4E-21 T 09-03-2017 IPR014756 Immunoglobulin E-set ARZXY2_RS16750 ae8d9d3ee1792c2d3da112f0a8f056a8 212 Pfam PF04234 CopC domain 31 122 3.3E-20 T 09-03-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 ARZXY2_RS16750 ae8d9d3ee1792c2d3da112f0a8f056a8 212 Gene3D G3DSA:2.60.40.1220 30 122 4.4E-22 T 09-03-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like ARZXY2_RS15315 c5ddef82c242841e45401eb52f2ae2e8 116 Pfam PF14016 Protein of unknown function (DUF4232) 3 114 3.6E-26 T 09-03-2017 IPR025326 Protein of unknown function DUF4232 ARZXY2_RS10000 8e68d8ccf96dc6ff43d7d92f42a4021e 513 Pfam PF14333 Domain of unknown function (DUF4389) 421 471 2.6E-9 T 09-03-2017 IPR025498 Protein of unknown function DUF4389 ARZXY2_RS10000 8e68d8ccf96dc6ff43d7d92f42a4021e 513 Pfam PF14333 Domain of unknown function (DUF4389) 281 352 1.1E-11 T 09-03-2017 IPR025498 Protein of unknown function DUF4389 ARZXY2_RS03995 5dea51caea3cb25b7b0596bacb1a28e2 148 Gene3D G3DSA:3.10.180.10 4 146 9.7E-45 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS03995 5dea51caea3cb25b7b0596bacb1a28e2 148 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 130 1.9E-10 T 09-03-2017 ARZXY2_RS03995 5dea51caea3cb25b7b0596bacb1a28e2 148 SUPERFAMILY SSF54593 4 144 1.93E-31 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS16335 a02fccda892a93fd3aa8c1fd4805fdfe 100 Pfam PF13828 Domain of unknown function (DUF4190) 33 91 4.7E-9 T 09-03-2017 IPR025241 Domain of unknown function DUF4190 ARZXY2_RS19060 44cf5631db957b182a409ce1c64ce086 107 Pfam PF10688 Bacterial inner membrane protein 4 78 9.5E-9 T 09-03-2017 IPR019629 Uncharacterised protein family HI1736/YgjV ARZXY2_RS01210 6dc9e240b5399851025faf0c779caf94 155 SUPERFAMILY SSF52833 4 153 2.83E-45 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS01210 6dc9e240b5399851025faf0c779caf94 155 PIRSF PIRSF000239 1 149 8.0E-21 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS01210 6dc9e240b5399851025faf0c779caf94 155 Gene3D G3DSA:3.40.30.10 3 152 1.8E-45 T 09-03-2017 IPR012336 Thioredoxin-like fold ARZXY2_RS01210 6dc9e240b5399851025faf0c779caf94 155 Pfam PF00578 AhpC/TSA family 7 134 4.2E-36 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 ARZXY2_RS09300 446438ba90b8e8f623f910d606af88ab 481 SMART SM00507 388 440 2.3E-6 T 09-03-2017 IPR003615 HNH nuclease ARZXY2_RS09300 446438ba90b8e8f623f910d606af88ab 481 Pfam PF02720 Domain of unknown function (DUF222) 14 397 4.9E-26 T 09-03-2017 IPR003870 Domain of unknown function DUF222 ARZXY2_RS15415 49750787316b1105bbe8ffb4fb24812d 275 Pfam PF07920 Protein of unknown function (DUF1684) 133 271 9.3E-34 T 09-03-2017 IPR012467 Protein of unknown function DUF1684 ARZXY2_RS08960 8abff132fc31a66fffe7735dcd35626e 216 Pfam PF02361 Cobalt transport protein 24 201 1.4E-15 T 09-03-2017 IPR003339 ABC/ECF transporter, transmembrane component ARZXY2_RS02835 fa9bed93f9e35a8d272dd1a3563e72ce 223 Pfam PF03458 UPF0126 domain 96 170 2.9E-22 T 09-03-2017 IPR005115 Uncharacterised domain UPF0126 ARZXY2_RS02835 fa9bed93f9e35a8d272dd1a3563e72ce 223 Pfam PF03458 UPF0126 domain 9 84 1.6E-20 T 09-03-2017 IPR005115 Uncharacterised domain UPF0126 ARZXY2_RS09475 063a6b8afe5ff3b714e3bcf3338b3eae 388 SUPERFAMILY SSF56601 40 348 1.68E-55 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS09475 063a6b8afe5ff3b714e3bcf3338b3eae 388 Pfam PF00144 Beta-lactamase 68 300 2.5E-39 T 09-03-2017 IPR001466 Beta-lactamase-related ARZXY2_RS09475 063a6b8afe5ff3b714e3bcf3338b3eae 388 Gene3D G3DSA:3.40.710.10 65 354 4.7E-57 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like ARZXY2_RS17140 3a0ffd673ce268f47fd67a419814cf83 131 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 4 92 2.1E-14 T 09-03-2017 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 ARZXY2_RS02260 03a205ca8617e45fde24f5ec36b99193 310 SUPERFAMILY SSF52980 191 305 3.54E-6 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS18275 546d3c068e869e44f9528000ed382a51 277 SUPERFAMILY SSF51695 33 270 1.31E-54 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS18275 546d3c068e869e44f9528000ed382a51 277 Gene3D G3DSA:3.20.20.190 33 276 2.6E-60 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 ARZXY2_RS18275 546d3c068e869e44f9528000ed382a51 277 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 38 264 4.0E-31 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 ARZXY2_RS11870 a988fe59b572dfae8c6a1fee409547e2 312 Gene3D G3DSA:3.40.50.620 4 114 2.4E-5 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold ARZXY2_RS13235 6a9d87abdc79546f84a9089c63af3d7e 732 Gene3D G3DSA:1.50.10.10 375 589 2.7E-12 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 ARZXY2_RS13235 6a9d87abdc79546f84a9089c63af3d7e 732 SUPERFAMILY SSF48208 336 722 1.45E-49 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 ARZXY2_RS01815 438b265b436e201f4aacd84276ddd4f0 298 SMART SM00880 12 266 4.6E-29 T 09-03-2017 IPR007899 CHAD domain ARZXY2_RS01815 438b265b436e201f4aacd84276ddd4f0 298 Pfam PF05235 CHAD domain 13 234 4.8E-34 T 09-03-2017 IPR007899 CHAD domain ARZXY2_RS19205 5f73c7979533647e524bd40becee9109 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 320 2.1E-52 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS09050 de1011d5ae4d51a76ecf9b96c8221770 313 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 295 1.8E-83 T 09-03-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA ARZXY2_RS18175 18a36f34c5acc7c85ddbe7cea3111314 247 Gene3D G3DSA:3.40.50.880 33 215 1.7E-41 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS18175 18a36f34c5acc7c85ddbe7cea3111314 247 Pfam PF03575 Peptidase family S51 35 211 1.7E-31 T 09-03-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 ARZXY2_RS18175 18a36f34c5acc7c85ddbe7cea3111314 247 SUPERFAMILY SSF52317 35 212 1.83E-23 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like ARZXY2_RS07450 bc9418118ea4e989af2f055e8f653b84 254 Pfam PF03883 Protein of unknown function (DUF328) 2 220 4.3E-41 T 09-03-2017 IPR005583 Peroxide stress protein YaaA ARZXY2_RS03430 6b57a0f8691442f71586d1010102079d 199 SUPERFAMILY SSF160369 1 157 4.71E-42 T 09-03-2017 ARZXY2_RS03430 6b57a0f8691442f71586d1010102079d 199 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 09-03-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 ARZXY2_RS03430 6b57a0f8691442f71586d1010102079d 199 Pfam PF00466 Ribosomal protein L10 2 98 1.4E-23 T 09-03-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 ARZXY2_RS03430 6b57a0f8691442f71586d1010102079d 199 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 23.277 T 09-03-2017 IPR022973 Ribosomal protein L10 ARZXY2_RS15060 1e8e5a4c35970579a8ceb488341b4583 645 SUPERFAMILY SSF51905 6 207 7.93E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15060 1e8e5a4c35970579a8ceb488341b4583 645 Gene3D G3DSA:3.50.50.60 5 205 5.2E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 ARZXY2_RS15060 1e8e5a4c35970579a8ceb488341b4583 645 Pfam PF13454 FAD-NAD(P)-binding 10 185 4.2E-43 T 09-03-2017 ARZXY2_RS18280 9ba6079d4bb09465eea85a11ed782963 283 Gene3D G3DSA:3.40.50.720 1 225 4.5E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS18280 9ba6079d4bb09465eea85a11ed782963 283 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 201 1.8E-8 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 ARZXY2_RS18280 9ba6079d4bb09465eea85a11ed782963 283 SUPERFAMILY SSF51735 1 275 1.8E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS01360 79fb0a6effd5316c263e51fc2bfab6cb 314 SUPERFAMILY SSF52151 13 84 4.45E-18 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ARZXY2_RS01360 79fb0a6effd5316c263e51fc2bfab6cb 314 SUPERFAMILY SSF52151 135 223 4.45E-18 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 ARZXY2_RS18050 9b8854ad487193e60be42996b458ef53 191 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 1.8E-14 T 09-03-2017 IPR022062 Protein of unknown function DUF3618 ARZXY2_RS18095 50edaa74d0d3d9f19ca0b72b160a6755 208 Pfam PF13580 SIS domain 20 153 5.1E-26 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 ARZXY2_RS18095 50edaa74d0d3d9f19ca0b72b160a6755 208 SUPERFAMILY SSF53697 15 192 9.3E-41 T 09-03-2017 ARZXY2_RS18095 50edaa74d0d3d9f19ca0b72b160a6755 208 Gene3D G3DSA:3.40.50.10490 17 194 2.4E-47 T 09-03-2017 ARZXY2_RS19520 d2ee30ec5ae6c6a126d328ac7f894446 185 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 39 128 1.2E-6 T 09-03-2017 IPR018958 SMI1/KNR4-like domain ARZXY2_RS19170 6e73755d166e2bcdd22fe01c8eb02395 71 Gene3D G3DSA:1.10.10.60 25 68 1.7E-4 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS04140 34cf5ace0a0d7637eccf5140eb27c422 419 Pfam PF02646 RmuC family 83 378 6.2E-81 T 09-03-2017 IPR003798 DNA recombination RmuC ARZXY2_RS05420 5e8af00760c7446994423b76935ba733 155 Pfam PF14340 Domain of unknown function (DUF4395) 1 129 1.1E-39 T 09-03-2017 IPR025508 Domain of unknown function DUF4395 ARZXY2_RS20770 17a3ec05e1993a385c839d1dc18af24b 105 Gene3D G3DSA:3.20.20.30 16 105 1.5E-10 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS20770 17a3ec05e1993a385c839d1dc18af24b 105 SUPERFAMILY SSF51679 20 104 2.47E-8 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 ARZXY2_RS00900 ee45c9832cac3d7086869e61b3963980 111 Pfam PF11239 Protein of unknown function (DUF3040) 1 79 4.5E-21 T 09-03-2017 IPR021401 Protein of unknown function DUF3040 ARZXY2_RS17555 1ab6a4e04e34ed0d985d5ac604ae02a9 351 Pfam PF03824 High-affinity nickel-transport protein 54 335 6.5E-51 T 09-03-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 ARZXY2_RS02695 2d25e1d9bc22440fe610f6ae1ba0beef 361 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 215 346 3.4E-18 T 09-03-2017 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 236 1.7E-5 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 Gene3D G3DSA:3.30.360.10 137 329 2.8E-51 T 09-03-2017 ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 SUPERFAMILY SSF51735 2 147 1.02E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 SUPERFAMILY SSF55347 128 276 5.23E-30 T 09-03-2017 ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 120 6.7E-22 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 ARZXY2_RS16915 36a3449652be85797340beec13fbbc39 331 Gene3D G3DSA:3.40.50.720 2 136 1.9E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain ARZXY2_RS05205 cbd95b9f0fe6395096d42977ecf664e9 261 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 236 4.1E-31 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ARZXY2_RS05205 cbd95b9f0fe6395096d42977ecf664e9 261 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 96 236 4.2E-21 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 ARZXY2_RS14930 420281c3dce78b0f04d4e3196a837657 280 SUPERFAMILY SSF53335 25 190 6.48E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS14930 420281c3dce78b0f04d4e3196a837657 280 Gene3D G3DSA:3.40.50.150 53 159 5.4E-4 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase ARZXY2_RS09750 4857df9040d0feee91f89a778b912100 586 Pfam PF02538 Hydantoinase B/oxoprolinase 6 536 1.7E-115 T 09-03-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 ARZXY2_RS11615 906cb30e9f5e473955cdd188e424b9af 97 Pfam PF03795 YCII-related domain 12 85 4.6E-11 T 09-03-2017 IPR005545 YCII-related ARZXY2_RS11615 906cb30e9f5e473955cdd188e424b9af 97 SUPERFAMILY SSF54909 1 87 6.97E-19 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel ARZXY2_RS11615 906cb30e9f5e473955cdd188e424b9af 97 Gene3D G3DSA:3.30.70.1060 2 87 1.1E-15 T 09-03-2017 ARZXY2_RS05310 4e029c44a96f99f6abe4a1b2697b2877 430 Pfam PF01594 Domain of unknown function DUF20 104 420 6.7E-57 T 09-03-2017 IPR002549 Transmembrane protein TqsA-like ARZXY2_RS19005 ecc0e978fbd9829b412a5477b7df49c7 437 Pfam PF14067 LssY C-terminus 70 260 7.8E-73 T 09-03-2017 IPR025902 LssY-like C-terminal domain ARZXY2_RS09630 5ae143fac71eee67a22cab3b809c486d 369 SUPERFAMILY SSF53850 54 350 2.17E-41 T 09-03-2017 ARZXY2_RS09630 5ae143fac71eee67a22cab3b809c486d 369 Pfam PF01547 Bacterial extracellular solute-binding protein 67 310 3.5E-12 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 ARZXY2_RS09630 5ae143fac71eee67a22cab3b809c486d 369 Gene3D G3DSA:3.40.190.10 160 296 4.4E-19 T 09-03-2017 ARZXY2_RS09630 5ae143fac71eee67a22cab3b809c486d 369 Gene3D G3DSA:3.40.190.10 297 335 5.0E-36 T 09-03-2017 ARZXY2_RS09630 5ae143fac71eee67a22cab3b809c486d 369 Gene3D G3DSA:3.40.190.10 1 155 5.0E-36 T 09-03-2017 ARZXY2_RS01180 2a01bae280c27ef4be414329c802431f 82 SUPERFAMILY SSF140453 5 59 3.53E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like ARZXY2_RS15895 d8553946cb52d790c48da8e7e4fdbfef 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 11 42 0.0029 T 09-03-2017 IPR011437 Domain of unknown function DUF1540 ARZXY2_RS15895 d8553946cb52d790c48da8e7e4fdbfef 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 61 92 0.0035 T 09-03-2017 IPR011437 Domain of unknown function DUF1540 ARZXY2_RS01725 dd84a4b69a506e2bd73ef6a2c3746112 303 Gene3D G3DSA:3.90.79.10 30 132 9.9E-11 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01725 dd84a4b69a506e2bd73ef6a2c3746112 303 Gene3D G3DSA:3.90.79.10 165 219 9.9E-11 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01725 dd84a4b69a506e2bd73ef6a2c3746112 303 SUPERFAMILY SSF55811 21 77 1.1E-10 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01725 dd84a4b69a506e2bd73ef6a2c3746112 303 SUPERFAMILY SSF55811 105 119 1.1E-10 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS01725 dd84a4b69a506e2bd73ef6a2c3746112 303 SUPERFAMILY SSF55811 164 220 1.1E-10 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 ARZXY2_RS14295 a4440a8f5b71a16712d96e7bd451bc4f 209 Pfam PF01810 LysE type translocator 19 207 2.6E-40 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS03785 0e041378eae9697dc1d1778727cace97 345 SUPERFAMILY SSF51430 13 334 3.8E-86 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS03785 0e041378eae9697dc1d1778727cace97 345 Gene3D G3DSA:3.20.20.100 12 334 1.4E-81 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS03785 0e041378eae9697dc1d1778727cace97 345 Pfam PF00248 Aldo/keto reductase family 28 333 9.8E-67 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain ARZXY2_RS13240 35ce6825c317720227e6231cafefe4b6 361 Pfam PF03631 Virulence factor BrkB 79 338 1.4E-33 T 09-03-2017 IPR017039 Virulence factor BrkB ARZXY2_RS13035 6f0809e2ab775e168216091f4fdb2a37 316 Gene3D G3DSA:2.70.98.10 64 311 1.2E-25 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS13035 6f0809e2ab775e168216091f4fdb2a37 316 Pfam PF01263 Aldose 1-epimerase 67 307 1.2E-23 T 09-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 ARZXY2_RS13035 6f0809e2ab775e168216091f4fdb2a37 316 SUPERFAMILY SSF74650 23 312 8.79E-43 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 ARZXY2_RS14445 3fda750e6ae7502c9994dc3785da56aa 252 Pfam PF01311 Bacterial export proteins, family 1 11 240 5.9E-52 T 09-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 ARZXY2_RS14445 3fda750e6ae7502c9994dc3785da56aa 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 6.8E-28 T 09-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 ARZXY2_RS14445 3fda750e6ae7502c9994dc3785da56aa 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 77 96 6.8E-28 T 09-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 ARZXY2_RS14445 3fda750e6ae7502c9994dc3785da56aa 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 19 40 6.8E-28 T 09-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 ARZXY2_RS14445 3fda750e6ae7502c9994dc3785da56aa 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 6.8E-28 T 09-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 ARZXY2_RS00115 c7ab1fa351407fe6af756f249ac8626a 85 Pfam PF02583 Metal-sensitive transcriptional repressor 11 80 4.1E-24 T 09-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 ARZXY2_RS10720 9b53a6a617f86fc6d21b39389e1f57c5 253 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 27 247 2.0E-89 T 09-03-2017 ARZXY2_RS10720 9b53a6a617f86fc6d21b39389e1f57c5 253 Pfam PF13829 Domain of unknown function (DUF4191) 30 248 2.1E-81 T 09-03-2017 IPR025445 Protein of unknown function DUF4191 ARZXY2_RS15935 e732bb70bfe2d0c1208530f0a1359624 97 Gene3D G3DSA:3.30.70.1120 1 96 4.5E-35 T 09-03-2017 IPR007546 Protein of unknown function DUF503 ARZXY2_RS15935 e732bb70bfe2d0c1208530f0a1359624 97 SUPERFAMILY SSF103007 1 95 2.48E-30 T 09-03-2017 IPR007546 Protein of unknown function DUF503 ARZXY2_RS15935 e732bb70bfe2d0c1208530f0a1359624 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 7.9E-31 T 09-03-2017 IPR007546 Protein of unknown function DUF503 ARZXY2_RS12790 16065b4420667b65c43eb61f13bccb8f 138 SUPERFAMILY SSF54593 1 129 2.93E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS12790 16065b4420667b65c43eb61f13bccb8f 138 Gene3D G3DSA:3.10.180.10 9 134 5.2E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase ARZXY2_RS00960 51a4344340a96246efeabf11fb189bbd 162 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 146 2.6E-16 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase ARZXY2_RS00960 51a4344340a96246efeabf11fb189bbd 162 SUPERFAMILY SSF55961 1 146 1.87E-16 T 09-03-2017 ARZXY2_RS00960 51a4344340a96246efeabf11fb189bbd 162 Gene3D G3DSA:3.30.530.20 1 146 1.2E-10 T 09-03-2017 IPR023393 START-like domain ARZXY2_RS05535 fd5afaa3645b7dde91bcc9fc9e0d8c66 165 Pfam PF04138 GtrA-like protein 41 159 2.5E-15 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 ARZXY2_RS19995 e5fca118a637bd8af0eae662bc241559 452 SUPERFAMILY SSF53474 220 339 5.35E-7 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold ARZXY2_RS21040 8613abc1dac9214db8a261491d89a9a7 101 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 59 99 3.8E-9 T 09-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 ARZXY2_RS10100 e946d68276c43aedfd5e294a569429a1 247 Pfam PF01925 Sulfite exporter TauE/SafE 7 233 1.5E-19 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 ARZXY2_RS01240 8524686714af12eb6f12dddf8dfcddde 267 SUPERFAMILY SSF51658 1 257 8.51E-54 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS01240 8524686714af12eb6f12dddf8dfcddde 267 Gene3D G3DSA:3.20.20.150 1 260 9.5E-64 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS01240 8524686714af12eb6f12dddf8dfcddde 267 PIRSF PIRSF006241 1 266 1.7E-63 T 09-03-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 ARZXY2_RS01240 8524686714af12eb6f12dddf8dfcddde 267 Pfam PF01261 Xylose isomerase-like TIM barrel 21 222 9.9E-26 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain ARZXY2_RS09660 ffb5266210b14892efa686a2aef9e686 493 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 479 42.92 T 09-03-2017 IPR003846 Uncharacterised protein family UPF0061 ARZXY2_RS09660 ffb5266210b14892efa686a2aef9e686 493 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 26 462 1.3E-112 T 09-03-2017 IPR003846 Uncharacterised protein family UPF0061 ARZXY2_RS15280 01f7acfaeb655cb5d05b0eb64c2c102c 497 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 210 2.2E-8 T 09-03-2017 ARZXY2_RS00815 b34e2a32bb226ef5144a8a93cc7fac08 298 SUPERFAMILY SSF56281 28 108 3.5E-22 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00815 b34e2a32bb226ef5144a8a93cc7fac08 298 SUPERFAMILY SSF56281 136 253 3.5E-22 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00815 b34e2a32bb226ef5144a8a93cc7fac08 298 Gene3D G3DSA:3.60.15.10 23 287 4.1E-55 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS00815 b34e2a32bb226ef5144a8a93cc7fac08 298 Pfam PF12706 Beta-lactamase superfamily domain 45 248 1.2E-26 T 09-03-2017 IPR001279 Metallo-beta-lactamase ARZXY2_RS04015 535b73d3ce4ef0f4daf08e891375bc54 150 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 12 131 16.864 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ARZXY2_RS04015 535b73d3ce4ef0f4daf08e891375bc54 150 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 14 126 5.6E-21 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 ARZXY2_RS19715 50e00fa5cf7905ae83fd29cc38fb6fc5 349 Pfam PF13515 Fusaric acid resistance protein-like 212 337 2.0E-23 T 09-03-2017 ARZXY2_RS09195 9f7d125ee15aba5b125cab9ff9d89238 188 Pfam PF01872 RibD C-terminal domain 75 166 7.6E-13 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 ARZXY2_RS09195 9f7d125ee15aba5b125cab9ff9d89238 188 Gene3D G3DSA:3.40.430.10 6 181 2.0E-30 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS09195 9f7d125ee15aba5b125cab9ff9d89238 188 SUPERFAMILY SSF53597 6 177 1.57E-33 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 ARZXY2_RS06150 c0a15f0f08d763ca9e161f1c5da3ae93 115 Pfam PF02583 Metal-sensitive transcriptional repressor 26 111 4.4E-30 T 09-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 ARZXY2_RS15025 626f05f2cd94ecd92c6631f2ed9383f5 63 Pfam PF04328 Protein of unknown function (DUF466) 6 63 1.4E-21 T 09-03-2017 IPR007423 Protein of unknown function DUF466 ARZXY2_RS20090 4f0fec96f21e27433c2fce05cdda15ba 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 4.3E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS20090 4f0fec96f21e27433c2fce05cdda15ba 192 Gene3D G3DSA:1.10.357.10 4 156 3.1E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 ARZXY2_RS20090 4f0fec96f21e27433c2fce05cdda15ba 192 SUPERFAMILY SSF46689 9 73 8.72E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 ARZXY2_RS20090 4f0fec96f21e27433c2fce05cdda15ba 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS20090 4f0fec96f21e27433c2fce05cdda15ba 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 ARZXY2_RS16645 3ae72db12590121915247b31b409afbf 99 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 7.1E-32 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 ARZXY2_RS07780 64f923899a4bff8e443aedd469c2ecd0 167 Pfam PF09406 Protein of unknown function (DUF2004) 63 167 2.5E-28 T 09-03-2017 IPR018546 Protein of unknown function DUF2004 ARZXY2_RS01255 54b170622328078d8d1dda615e682374 130 Gene3D G3DSA:3.40.1350.10 4 71 8.1E-4 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 ARZXY2_RS07645 ec1b74b56384b2bb99a9258e3bb51d1c 150 Pfam PF14017 Protein of unknown function (DUF4233) 25 128 2.0E-29 T 09-03-2017 IPR025327 Protein of unknown function DUF4233 ARZXY2_RS06090 50eb72b1215e6ea5d9d750569683cf3b 67 Pfam PF11666 Protein of unknown function (DUF2933) 9 58 1.4E-13 T 09-03-2017 IPR021682 Protein of unknown function DUF2933 ARZXY2_RS14330 d11a101abb31f5bcd3108ed38e94fc01 206 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 120 205 2.6E-16 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain ARZXY2_RS06410 c9b5aae6834d77696273e82bc516e99a 109 Pfam PF08774 VRR-NUC domain 33 82 1.4E-6 T 09-03-2017 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 ARZXY2_RS06410 c9b5aae6834d77696273e82bc516e99a 109 SMART SM00990 7 86 2.9E-15 T 09-03-2017 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 ARZXY2_RS03265 fcc3db74ed950af553588c144f857bbc 377 Pfam PF06224 Winged helix DNA-binding domain 35 374 1.0E-50 T 09-03-2017 IPR009351 Protein of unknown function DUF1006 ARZXY2_RS16155 a7cf18cf9e2f0cb397673dd5fd704e00 310 SUPERFAMILY SSF52980 200 304 2.25E-5 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 ARZXY2_RS18980 3430644dc85017dc4e062f97540df761 306 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 294 2.4E-81 T 09-03-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA ARZXY2_RS04575 781d32d393a728e2d5802b6240c1ef50 993 Pfam PF03699 Uncharacterised protein family (UPF0182) 22 824 1.8E-285 T 09-03-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 ARZXY2_RS04575 781d32d393a728e2d5802b6240c1ef50 993 Hamap MF_01600 UPF0182 protein . 13 900 19.007 T 09-03-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 ARZXY2_RS11315 90725af14da78fe9e631317d39d5bf5d 295 Pfam PF07179 SseB protein N-terminal domain 62 182 8.0E-36 T 09-03-2017 IPR009839 SseB protein N-terminal domain ARZXY2_RS18800 a3d3af8c71cb7ebb6672a4d6fe848bb8 140 Pfam PF08818 Domain of unknown function (DU1801) 25 127 4.5E-11 T 09-03-2017 IPR014922 Domain of unknown function DUF1801 ARZXY2_RS17430 b95ffa20400b00b988ca62366d6654c8 130 Pfam PF06993 Protein of unknown function (DUF1304) 11 122 4.3E-33 T 09-03-2017 IPR009732 Protein of unknown function DUF1304 ARZXY2_RS04720 ebcbd4efb8b42ca824454d1ce3d2be91 234 Pfam PF13761 Domain of unknown function (DUF4166) 17 204 2.7E-52 T 09-03-2017 IPR025311 Domain of unknown function DUF4166 ARZXY2_RS19500 81a1a2c8d75e911c3e8f46f7d07b1cf7 226 SUPERFAMILY SSF52283 135 215 2.04E-5 T 09-03-2017 ARZXY2_RS08110 443f97303230308b19e5914bfcb6dc2d 433 Pfam PF13367 Protease prsW family 140 328 4.4E-48 T 09-03-2017 IPR026898 Protease PrsW GO:0008233 ARZXY2_RS04920 e49b483df0ac40db035e4c0de6b55100 285 Pfam PF00482 Type II secretion system (T2SS), protein F 113 238 2.0E-9 T 09-03-2017 IPR018076 Type II secretion system F domain ARZXY2_RS19680 9f34613de96538f9e4ab001b1470cbf9 302 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 10 139 2.9E-23 T 09-03-2017 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain ARZXY2_RS17970 b33acbf1ce5b5fdd89926da0a69a0c7e 174 Pfam PF11377 Protein of unknown function (DUF3180) 9 145 2.1E-33 T 09-03-2017 IPR021517 Protein of unknown function DUF3180 ARZXY2_RS10450 6324bfb1d42534bc4ebd603d8e3bc5a1 163 SUPERFAMILY SSF52402 4 155 2.34E-29 T 09-03-2017 ARZXY2_RS09995 ecd5b1fe12f5ff47c155760443ec5957 256 Pfam PF12679 ABC-2 family transporter protein 6 196 3.0E-8 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 ARZXY2_RS10540 40e791d212c18e31c2866e0d2ddfce3a 267 Pfam PF11361 Protein of unknown function (DUF3159) 72 258 2.9E-66 T 09-03-2017 IPR016566 Uncharacterised conserved protein UCP010219 ARZXY2_RS20405 e489cda80f409268137bc0392bff8e60 214 Pfam PF01810 LysE type translocator 15 204 1.3E-20 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 ARZXY2_RS17365 821936df72534b69965d1d347c9e695f 347 Pfam PF13515 Fusaric acid resistance protein-like 206 339 1.6E-26 T 09-03-2017 ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 Pfam PF03023 MviN-like protein 40 507 4.2E-69 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 PRINTS PR01806 Virulence factor MviN signature 45 64 6.2E-6 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 PRINTS PR01806 Virulence factor MviN signature 165 186 6.2E-6 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 PRINTS PR01806 Virulence factor MviN signature 64 80 6.2E-6 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 PRINTS PR01806 Virulence factor MviN signature 141 165 6.2E-6 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS18625 d48be0d475e304fc2b1ea7f061a16df7 672 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 16 552 9.0E-82 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ ARZXY2_RS07205 48a42ea20533bd66562e88c0d4379cb9 164 Pfam PF04213 Htaa 13 155 5.6E-27 T 09-03-2017 IPR007331 Htaa ARZXY2_RS07315 26918a50d225a2915f99d067ba0ece07 167 Pfam PF11343 Protein of unknown function (DUF3145) 9 165 7.1E-76 T 09-03-2017 IPR021491 Protein of unknown function DUF3145 ARZXY2_RS05945 c1277c0433a63dfdd4208f44283e1cef 683 Gene3D G3DSA:3.30.565.10 80 193 2.6E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS05945 c1277c0433a63dfdd4208f44283e1cef 683 SUPERFAMILY SSF55874 80 135 4.42E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain ARZXY2_RS11260 f710c231eb431663656fc233e416be41 210 Pfam PF04402 Protein of unknown function (DUF541) 6 205 3.1E-37 T 09-03-2017 IPR007497 Protein of unknown function DUF541 ARZXY2_RS09690 16a7c891994fab4166a47e1dcaaacb0e 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 320 1.0E-45 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS17420 8c61103ddac881f36cbaba9be91ee0e6 446 Pfam PF01757 Acyltransferase family 14 341 9.6E-23 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 ARZXY2_RS13375 a62a220744ebe311b0f8ade68f000693 144 Pfam PF07681 DoxX 15 95 1.2E-15 T 09-03-2017 IPR032808 DoxX family ARZXY2_RS16080 e1a1431feffd296765aad409a54273ec 262 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 122 3.6E-19 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 ARZXY2_RS16080 e1a1431feffd296765aad409a54273ec 262 SUPERFAMILY SSF161098 24 218 6.87E-37 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16080 e1a1431feffd296765aad409a54273ec 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 231 2.0E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS16080 e1a1431feffd296765aad409a54273ec 262 Gene3D G3DSA:1.10.3720.10 25 231 7.5E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 ARZXY2_RS09790 99cfbf067906b05efc0d54048e7360d4 153 Pfam PF06210 Protein of unknown function (DUF1003) 30 125 9.9E-25 T 09-03-2017 IPR010406 Protein of unknown function DUF1003 ARZXY2_RS04600 b5b73e2bb71c47f2d3e0aa91c3636de9 733 SUPERFAMILY SSF56954 339 617 6.28E-9 T 09-03-2017 ARZXY2_RS04600 b5b73e2bb71c47f2d3e0aa91c3636de9 733 SUPERFAMILY SSF56954 55 87 6.28E-9 T 09-03-2017 ARZXY2_RS04600 b5b73e2bb71c47f2d3e0aa91c3636de9 733 SUPERFAMILY SSF56954 173 239 6.28E-9 T 09-03-2017 ARZXY2_RS04600 b5b73e2bb71c47f2d3e0aa91c3636de9 733 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 92 209 8.2E-11 T 09-03-2017 IPR007621 TPM domain ARZXY2_RS19290 b8582fed434cc405a6a8c0995d778730 204 SUPERFAMILY SSF53098 8 196 4.81E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 ARZXY2_RS01840 7b44288297e72494d0fdb1aaef5f977d 209 Pfam PF00482 Type II secretion system (T2SS), protein F 75 195 4.4E-11 T 09-03-2017 IPR018076 Type II secretion system F domain ARZXY2_RS12965 cd0d4728bf5bf37b7cfcd1ca6bf32277 181 Pfam PF01478 Type IV leader peptidase family 25 147 9.5E-10 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 ARZXY2_RS05900 686f72ac82089b78befbc4e5d310d88a 1163 SUPERFAMILY SSF52540 208 257 1.95E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS05900 686f72ac82089b78befbc4e5d310d88a 1163 SUPERFAMILY SSF52540 303 433 1.95E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase ARZXY2_RS00670 62589d44ab05fe209081661e6285b689 220 SUPERFAMILY SSF49464 148 201 5.76E-5 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain ARZXY2_RS07750 b4ba95a06fdb59db4a3f5b338a11f7fa 298 Pfam PF01882 Protein of unknown function DUF58 37 122 1.0E-21 T 09-03-2017 IPR002881 Domain of unknown function DUF58 ARZXY2_RS19245 355903c223ad101747619add736e52bb 237 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 26 197 2.4E-33 T 09-03-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 ARZXY2_RS15360 16d23038aeb58a343aaa6b9754bf1a7d 212 Pfam PF09335 SNARE associated Golgi protein 32 158 1.6E-12 T 09-03-2017 IPR032816 SNARE associated Golgi protein ARZXY2_RS15740 9c0ec2f72a3ee177e7298393168365e9 215 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 90 174 7.5E-12 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain ARZXY2_RS07045 60a97202ffed02c93a3f1a35dab78461 111 Pfam PF10611 Protein of unknown function (DUF2469) 1 101 1.8E-52 T 09-03-2017 IPR019592 Protein of unknown function DUF2469 ARZXY2_RS02470 b12fdeb5ea98f9ae017741b72b2ab6fb 585 Pfam PF13196 Protein of unknown function (DUF4012) 198 349 8.3E-46 T 09-03-2017 IPR025101 Protein of unknown function DUF4012 ARZXY2_RS05395 4081431eaacba4fa7e2c14eb71f27aed 236 Pfam PF09335 SNARE associated Golgi protein 44 171 2.5E-21 T 09-03-2017 IPR032816 SNARE associated Golgi protein ARZXY2_RS08050 2b3a19ad4b006aae3a0a008ce853051f 124 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 1.5E-20 T 09-03-2017 IPR009293 Uncharacterised protein family UPF0478 ARZXY2_RS19350 d9ccb4f2f01110692c447cfc980d8569 304 Pfam PF04986 Putative transposase 9 156 2.6E-36 T 09-03-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 ARZXY2_RS04385 85b56a789f5a118bcb99b21fa34538e4 202 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 1 192 4.2E-48 T 09-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 ARZXY2_RS04385 85b56a789f5a118bcb99b21fa34538e4 202 Pfam PF01914 MarC family integral membrane protein 4 196 5.7E-52 T 09-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 ARZXY2_RS00455 8a173ea9bcd7688ea9e27b67b983d197 88 Pfam PF08410 Domain of unknown function (DUF1737) 10 56 6.0E-22 T 09-03-2017 IPR013619 Domain of unknown function DUF1737 ARZXY2_RS09015 bc138453cf9b1361c55a883d082b9705 254 PIRSF PIRSF006648 4 252 2.2E-25 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 ARZXY2_RS09015 bc138453cf9b1361c55a883d082b9705 254 Pfam PF01061 ABC-2 type transporter 23 222 1.9E-18 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 ARZXY2_RS15305 02adef4e803e37d0566294a5639c761c 242 Pfam PF07987 Domain of unkown function (DUF1775) 33 179 4.5E-45 T 09-03-2017 IPR012533 GLE1, N-terminal, bacteria ARZXY2_RS08760 aa6af331a78149cbc2bbf53aaf3c126b 488 Pfam PF13440 Polysaccharide biosynthesis protein 40 328 1.1E-53 T 09-03-2017 ARZXY2_RS13115 7b7b3ab7a8667df0d2ed9e1318c36a16 234 Pfam PF04417 Protein of unknown function (DUF501) 42 170 3.5E-40 T 09-03-2017 IPR007511 Protein of unknown function DUF501 ARZXY2_RS13065 1777959cb83bc76f326ef807e3c8e03c 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 305 9.3E-53 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS05940 1fa6b788fd4d661fb1556f14e4499fd8 617 Pfam PF03235 Protein of unknown function DUF262 14 255 3.4E-27 T 09-03-2017 IPR004919 Domain of unknown function DUF262 ARZXY2_RS18950 f40c034c32571f27056ecb2c92d1eeb8 90 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 78 9.6E-37 T 09-03-2017 IPR018735 Protein of unknown function DUF2277 ARZXY2_RS12465 3e0c2bc97057752078e3bbcce70db101 199 Pfam PF03703 Bacterial PH domain 86 158 4.4E-10 T 09-03-2017 IPR005182 Domain of unknown function DUF304 ARZXY2_RS08435 9fa8d2f4a7a57f462394a50b0e0669b7 129 Pfam PF11255 Protein of unknown function (DUF3054) 12 114 2.3E-27 T 09-03-2017 IPR021414 Protein of unknown function DUF3054 ARZXY2_RS04440 712189b5dc29282ae35fd28217011f41 74 Pfam PF11305 Protein of unknown function (DUF3107) 1 72 4.3E-26 T 09-03-2017 IPR021456 Protein of unknown function DUF3107 ARZXY2_RS05370 f14be407fb0f814981ae52cb31a3e79b 188 Pfam PF09438 Domain of unknown function (DUF2017) 11 180 2.1E-47 T 09-03-2017 IPR018561 Domain of unknown function DUF2017 ARZXY2_RS05860 dce3c79aa51cb6e4658a05f1606f44d3 199 Pfam PF08747 Domain of unknown function (DUF1788) 67 194 8.4E-41 T 09-03-2017 IPR014858 Protein of unknown function DUF1788 ARZXY2_RS08625 258180f9cb2c05554988b4be8760c2cd 673 Pfam PF13280 WYL domain 490 656 5.3E-28 T 09-03-2017 IPR026881 WYL domain ARZXY2_RS08625 258180f9cb2c05554988b4be8760c2cd 673 Pfam PF13280 WYL domain 149 318 1.6E-26 T 09-03-2017 IPR026881 WYL domain ARZXY2_RS06025 465b3cf33961518961075ca8e296128c 90 Pfam PF09851 Short C-terminal domain 60 85 1.0E-7 T 09-03-2017 IPR018649 SHOCT domain ARZXY2_RS12255 ed064b45c305a5f04e95f0c3a04b0489 251 Pfam PF02517 CAAX protease self-immunity 146 235 2.0E-16 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 ARZXY2_RS11580 29c114a602b76c86a409bfdb83b8d1fb 264 Pfam PF01925 Sulfite exporter TauE/SafE 17 254 4.2E-41 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 ARZXY2_RS00345 b4b3162845f12f5b1ff865183e607cd8 399 Pfam PF00999 Sodium/hydrogen exchanger family 13 371 1.6E-44 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 ARZXY2_RS01850 534920b799c0fa6338b5032ff5a29396 130 Pfam PF07811 TadE-like protein 21 63 8.9E-6 T 09-03-2017 IPR012495 TadE-like ARZXY2_RS05475 8d33a2d86097bedf828bcc25cafb8fc7 137 Gene3D G3DSA:1.10.10.10 3 133 4.5E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS05475 8d33a2d86097bedf828bcc25cafb8fc7 137 SUPERFAMILY SSF46785 3 132 5.84E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain ARZXY2_RS12860 464c68a9404812dfc8f48b5738029e4c 329 Pfam PF01944 Stage II sporulation protein M 108 278 1.6E-34 T 09-03-2017 IPR002798 Stage II sporulation protein M-like ARZXY2_RS18030 7600758be168130853a225d39a03d6b9 326 Gene3D G3DSA:1.10.287.850 8 85 8.2E-4 T 09-03-2017 IPR029013 HP0062-like domain ARZXY2_RS08290 78f83cfdc5a9931864673b6a346555ff 289 SMART SM00909 74 171 6.3E-7 T 09-03-2017 IPR019606 GerMN domain ARZXY2_RS12000 d3adf33456c810bbc3104508c9e750c0 258 Pfam PF05709 Phage tail protein 42 214 3.8E-10 T 09-03-2017 IPR008841 Siphovirus-type tail component ARZXY2_RS04905 6d559360bda575240da07c26c137d977 448 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 3 163 1.9E-8 T 09-03-2017 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 ARZXY2_RS20155 c93d0f7878defcb4c3479ba818170695 405 Pfam PF13556 PucR C-terminal helix-turn-helix domain 338 396 3.9E-15 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain ARZXY2_RS02460 2e6ed33fd39593e39e20bbbbee11c47c 143 Pfam PF04892 VanZ like family 3 121 4.2E-18 T 09-03-2017 IPR006976 VanZ-like ARZXY2_RS15745 7adf069eaa013ca06b53d42a06f94c94 99 PIRSF PIRSF006909 1 99 2.4E-48 T 09-03-2017 IPR014447 Uncharacterised conserved protein UCP006909 ARZXY2_RS13140 f1aa4c9b341c8154af9a155814dda0d5 228 Pfam PF09335 SNARE associated Golgi protein 28 152 8.1E-19 T 09-03-2017 IPR032816 SNARE associated Golgi protein ARZXY2_RS20000 b4eada2a5617eb7c97dcdb269db470e7 142 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 132 9.3E-30 T 09-03-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV ARZXY2_RS01665 bd3622b5e77264aac0e9f245245f8c5b 132 SUPERFAMILY SSF55718 57 126 4.47E-5 T 09-03-2017 IPR003033 SCP2 sterol-binding domain ARZXY2_RS00380 97b753775f1a8af155168eabd0291b2e 92 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 82 3.5E-7 T 09-03-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 ARZXY2_RS12055 0ea59e14f86671dd3a60c8a073c9fc96 552 Gene3D G3DSA:3.90.550.10 316 424 2.4E-4 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases ARZXY2_RS05345 ce8954a3b77fea8fd2b58d94b20d0980 108 Pfam PF11238 Protein of unknown function (DUF3039) 42 96 2.2E-32 T 09-03-2017 IPR021400 Protein of unknown function DUF3039 ARZXY2_RS17965 981dbfdc529bd4b32b33db77450b4888 170 Pfam PF03703 Bacterial PH domain 82 159 1.6E-15 T 09-03-2017 IPR005182 Domain of unknown function DUF304 ARZXY2_RS10470 be13e6512c6df8b299758c4bcadcfb94 219 Pfam PF11452 Protein of unknown function (DUF3000) 9 211 6.6E-75 T 09-03-2017 IPR021555 Protein of unknown function DUF3000 ARZXY2_RS07930 7b173c8a423b5379352d1856382d8c3c 208 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS07930 7b173c8a423b5379352d1856382d8c3c 208 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 4.7E-8 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 ARZXY2_RS15215 9f4dd52bb76edbe3ddc7efaa3918e066 279 SUPERFAMILY SSF53955 204 266 1.6E-5 T 09-03-2017 IPR023346 Lysozyme-like domain ARZXY2_RS05550 b05d8a7f5b01b14cdbd4e4844aba2c48 223 Pfam PF07920 Protein of unknown function (DUF1684) 73 218 2.5E-38 T 09-03-2017 IPR012467 Protein of unknown function DUF1684 ARZXY2_RS01610 6f853d8f57bae997ce6f28911f68f509 530 Pfam PF00860 Permease family 77 483 3.6E-27 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 ARZXY2_RS05995 8408d64715bc506bc1f5290998969107 522 Pfam PF07751 Abi-like protein 39 267 4.1E-43 T 09-03-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like ARZXY2_RS04945 3eadffe79fe05a875ad3441027292a2d 149 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 12 56 2.6E-6 T 09-03-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal ARZXY2_RS18835 a9db33873a516521148a83edcf30898d 121 Pfam PF13453 Transcription factor zinc-finger 2 42 1.8E-20 T 09-03-2017 IPR027392 Transcription factor zinc-finger ARZXY2_RS06575 2c74b9d0bda4574fbbb284eb406969f6 563 SUPERFAMILY SSF53300 409 507 9.34E-5 T 09-03-2017 IPR002035 von Willebrand factor, type A ARZXY2_RS04035 508a8b89895f10d072b21fa1949505a4 141 Pfam PF08570 Protein of unknown function (DUF1761) 13 138 2.3E-30 T 09-03-2017 IPR013879 Protein of unknown function DUF1761 ARZXY2_RS19865 9f4dd5a3d4df153a10ec25d04cd9496c 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 196 262 6.8E-17 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 ARZXY2_RS19865 9f4dd5a3d4df153a10ec25d04cd9496c 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 106 172 1.4E-10 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 ARZXY2_RS19865 9f4dd5a3d4df153a10ec25d04cd9496c 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 24 89 4.5E-17 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 ARZXY2_RS00825 09484ecc855413ed9f11576d52331522 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 328 3.7E-44 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 ARZXY2_RS14935 91f22c59b37e6e557c1ea8626319b3bf 113 Pfam PF10724 Protein of unknown function (DUF2516) 11 102 6.5E-30 T 09-03-2017 IPR019662 Protein of unknown function DUF2516 ARZXY2_RS10550 369bd3133bedca352ac516f84ce8069f 240 Pfam PF12502 Protein of unknown function (DUF3710) 41 216 1.2E-66 T 09-03-2017 IPR022183 Protein of unknown function DUF3710 ARZXY2_RS19560 e144668bbf86d98679592b797a72411a 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 80 220 1.8E-12 T 09-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 ARZXY2_RS11050 2d14f76598fff1f85d65b667fa50ec1f 294 Pfam PF02616 Segregation and condensation protein ScpA 43 268 6.4E-44 T 09-03-2017 IPR003768 Segregation and condensation protein A