locus-tag	class	description
DA819_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DA819_RS00040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA819_RS00100	COG0592	DNA-directed DNA polymerase activity
DA819_RS00120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DA819_RS00125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DA819_RS00130	COG2084	Dehydrogenase
DA819_RS00155	COG3335	DDE superfamily endonuclease
DA819_RS00185	COG0316	Belongs to the HesB IscA family
DA819_RS00200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DA819_RS00205	COG1215	transferase activity, transferring glycosyl groups
DA819_RS00210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DA819_RS00220	COG1136	(ABC) transporter
DA819_RS00230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DA819_RS00240	COG1104	cysteine desulfurase activity
DA819_RS00250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DA819_RS00260	COG5002	protein histidine kinase activity
DA819_RS00265	COG0745	RESPONSE REGULATOR receiver
DA819_RS00300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DA819_RS00330	COG2226	methyltransferase
DA819_RS00350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DA819_RS00425	COG0772	Belongs to the SEDS family
DA819_RS00440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DA819_RS00450	COG0793	Belongs to the peptidase S41A family
DA819_RS00455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DA819_RS00490	COG1446	asparaginase
DA819_RS00495	COG0745	RESPONSE REGULATOR receiver
DA819_RS00510	COG0675	Transposase, IS605 OrfB family
DA819_RS00525	COG0840	transmembrane signaling receptor activity
DA819_RS00535	COG0457	Tetratricopeptide repeat
DA819_RS00535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DA819_RS00540	COG2201	protein-glutamate methylesterase activity
DA819_RS00550	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DA819_RS00565	COG1333	cytochrome c biogenesis protein
DA819_RS00585	COG5002	protein histidine kinase activity
DA819_RS00590	COG2770	Histidine kinase
DA819_RS00590	COG2208	phosphoserine phosphatase activity
DA819_RS00595	COG0768	penicillin binding
DA819_RS00605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DA819_RS00645	COG4447	cellulose binding
DA819_RS00650	COG1773	rubredoxin
DA819_RS00660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS00665	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS00670	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS00680	COG0612	Peptidase, M16
DA819_RS00685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DA819_RS00690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DA819_RS00695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DA819_RS00705	COG4251	negative regulation of phosphorylation
DA819_RS00720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DA819_RS00725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DA819_RS00730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DA819_RS00735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DA819_RS00740	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DA819_RS00745	COG0356	it plays a direct role in the translocation of protons across the membrane
DA819_RS00755	COG0442	prolyl-tRNA aminoacylation
DA819_RS00760	COG1555	photosystem II stabilization
DA819_RS00760	COG1596	polysaccharide export
DA819_RS00770	COG1104	cysteine desulfurase activity
DA819_RS00775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DA819_RS00780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA819_RS00780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DA819_RS00820	COG1598	PFAM Uncharacterised protein family UPF0150
DA819_RS00845	COG4636	protein conserved in cyanobacteria
DA819_RS00850	COG4636	protein conserved in cyanobacteria
DA819_RS00870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DA819_RS00970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA819_RS00975	COG0735	belongs to the Fur family
DA819_RS00995	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA819_RS00995	COG3409	Peptidoglycan-binding domain 1 protein
DA819_RS01005	COG0673	inositol 2-dehydrogenase activity
DA819_RS01015	COG2385	sporulation resulting in formation of a cellular spore
DA819_RS01075	COG2211	Major facilitator Superfamily
DA819_RS01080	COG1940	carbohydrate kinase activity
DA819_RS01100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DA819_RS01135	COG0798	PFAM Bile acid sodium symporter
DA819_RS01140	COG0431	NADPH-dependent FMN reductase
DA819_RS01145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DA819_RS01165	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DA819_RS01195	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DA819_RS01200	COG2203	Gaf domain
DA819_RS01200	COG3706	GGDEF domain
DA819_RS01200	COG4251	negative regulation of phosphorylation
DA819_RS01200	COG5001	Diguanylate cyclase
DA819_RS01265	COG4251	negative regulation of phosphorylation
DA819_RS01270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DA819_RS01335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DA819_RS01365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DA819_RS01405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DA819_RS01430	COG0523	cobalamin synthesis protein
DA819_RS01435	COG4106	trans-aconitate 2-methyltransferase activity
DA819_RS01480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DA819_RS01505	COG0484	heat shock protein binding
DA819_RS01550	COG4636	protein conserved in cyanobacteria
DA819_RS01560	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DA819_RS01575	COG2319	Wd-40 repeat
DA819_RS01575	COG5635	Nacht domain
DA819_RS01580	COG1748	Saccharopine dehydrogenase
DA819_RS01595	COG0629	single-stranded DNA binding
DA819_RS01610	COG2226	methyltransferase
DA819_RS01615	COG4399	Belongs to the UPF0754 family
DA819_RS01620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA819_RS01625	COG1160	GTP binding
DA819_RS01630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DA819_RS01640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DA819_RS01655	COG1799	cell septum assembly
DA819_RS01660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DA819_RS01665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DA819_RS01690	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DA819_RS01705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DA819_RS01705	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DA819_RS01710	COG0515	serine threonine protein kinase
DA819_RS01735	COG0776	regulation of translation
DA819_RS01740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DA819_RS01755	COG0322	excinuclease ABC activity
DA819_RS01760	COG2124	cytochrome p450
DA819_RS01775	COG1819	glycosyl
DA819_RS01790	COG0142	geranyltranstransferase activity
DA819_RS01800	COG0579	oxidoreductase
DA819_RS01825	COG0501	Belongs to the peptidase M48B family
DA819_RS01830	COG1704	LemA family
DA819_RS01835	COG3977	Valine--pyruvate aminotransferase
DA819_RS01855	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DA819_RS01890	COG2239	Acts as a magnesium transporter
DA819_RS01895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DA819_RS01905	COG2319	Wd-40 repeat
DA819_RS01905	COG3903	Transcriptional regulator
DA819_RS01920	COG1131	(ABC) transporter
DA819_RS01935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DA819_RS01940	COG3266	domain, Protein
DA819_RS01940	COG0515	serine threonine protein kinase
DA819_RS01945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DA819_RS01965	COG1834	amidinotransferase
DA819_RS01995	COG1166	arginine decarboxylase activity
DA819_RS02000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DA819_RS02005	COG1640	4-alpha-glucanotransferase
DA819_RS02015	COG1640	4-alpha-glucanotransferase
DA819_RS02040	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS02040	COG0515	serine threonine protein kinase
DA819_RS02095	COG3437	response regulator, receiver
DA819_RS02100	COG2197	response regulator
DA819_RS02110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DA819_RS02145	COG0519	Catalyzes the synthesis of GMP from XMP
DA819_RS02145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DA819_RS02310	COG1104	cysteine desulfurase activity
DA819_RS02320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DA819_RS02325	COG0805	protein transport
DA819_RS02345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS02360	COG1216	Glycosyl transferase, family 2
DA819_RS02370	COG0270	DNA (cytosine-5-)-methyltransferase activity
DA819_RS02375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DA819_RS02380	COG2203	Gaf domain
DA819_RS02380	COG3706	GGDEF domain
DA819_RS02380	COG4251	negative regulation of phosphorylation
DA819_RS02380	COG5001	Diguanylate cyclase
DA819_RS02385	COG1187	pseudouridine synthase activity
DA819_RS02415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DA819_RS02425	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS02430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DA819_RS02435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DA819_RS02435	COG4451	ribulose bisphosphate carboxylase, small
DA819_RS02440	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DA819_RS02445	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS02450	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS02455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA819_RS02460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS02470	COG1132	(ABC) transporter
DA819_RS02490	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DA819_RS02500	COG3842	ATPase activity
DA819_RS02510	COG1176	ABC-type spermidine putrescine transport system, permease component I
DA819_RS02515	COG1177	transmembrane transport
DA819_RS02520	COG0196	riboflavin kinase activity
DA819_RS02530	COG0714	Associated with various cellular activities
DA819_RS02540	COG1959	2 iron, 2 sulfur cluster binding
DA819_RS02545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DA819_RS02550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DA819_RS02555	COG1304	FMN binding
DA819_RS02570	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DA819_RS02575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DA819_RS02625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DA819_RS02625	COG1754	DNA topoisomerase type I activity
DA819_RS02635	COG0612	Peptidase, M16
DA819_RS02665	COG0390	transport system, permease component
DA819_RS02700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DA819_RS02705	COG0187	DNA topoisomerase II activity
DA819_RS02705	COG1372	Participates in initiation and elongation during chromosome replication
DA819_RS02730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DA819_RS02735	COG0740	serine-type endopeptidase activity
DA819_RS02740	COG0544	peptidyl-prolyl cis-trans isomerase activity
DA819_RS02745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DA819_RS02750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DA819_RS02755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DA819_RS02760	COG3829	transcription factor binding
DA819_RS02760	COG3290	protein histidine kinase activity
DA819_RS02770	COG4948	Mandelate Racemase Muconate Lactonizing
DA819_RS02785	COG0596	Alpha beta hydrolase
DA819_RS02800	COG3300	MHYT domain
DA819_RS02800	COG5001	Diguanylate cyclase
DA819_RS02900	COG2239	Acts as a magnesium transporter
DA819_RS02960	COG1185	polyribonucleotide nucleotidyltransferase activity
DA819_RS02975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA819_RS02980	COG0183	Belongs to the thiolase family
DA819_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS03000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DA819_RS03010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA819_RS03010	COG2022	thiamine diphosphate biosynthetic process
DA819_RS03055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DA819_RS03065	COG1122	ATPase activity
DA819_RS03070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DA819_RS03080	COG0515	serine threonine protein kinase
DA819_RS03080	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS03085	COG1064	alcohol dehydrogenase
DA819_RS03090	COG1454	alcohol dehydrogenase
DA819_RS03090	COG1012	belongs to the aldehyde dehydrogenase family
DA819_RS03115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA819_RS03140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DA819_RS03150	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS03155	COG1950	PFAM Membrane protein of
DA819_RS03165	COG1410	methionine synthase
DA819_RS03165	COG0646	methionine synthase
DA819_RS03170	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DA819_RS03175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DA819_RS03180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DA819_RS03185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DA819_RS03190	COG3906	Belongs to the UPF0473 family
DA819_RS03195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DA819_RS03240	COG0583	DNA-binding transcription factor activity
DA819_RS03245	COG1850	ribulose-bisphosphate carboxylase activity
DA819_RS03255	COG4451	ribulose bisphosphate carboxylase, small
DA819_RS03275	COG0006	proline dipeptidase activity
DA819_RS03280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS03295	COG2091	lysine biosynthetic process via aminoadipic acid
DA819_RS03325	COG1714	RDD family
DA819_RS03350	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS03350	COG0515	serine threonine protein kinase
DA819_RS03385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DA819_RS03390	COG2264	protein methyltransferase activity
DA819_RS03405	COG1252	NADH dehydrogenase
DA819_RS03475	COG2361	Protein of unknown function DUF86
DA819_RS03545	COG0003	Pfam Anion-transporting ATPase
DA819_RS03590	COG5001	Diguanylate cyclase
DA819_RS03590	COG5002	protein histidine kinase activity
DA819_RS03595	COG4783	chaperone-mediated protein folding
DA819_RS03600	COG4251	negative regulation of phosphorylation
DA819_RS03620	COG1331	Highly conserved protein containing a thioredoxin domain
DA819_RS03635	COG2267	carboxylic ester hydrolase activity
DA819_RS03645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DA819_RS03655	COG0028	Belongs to the TPP enzyme family
DA819_RS03665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA819_RS03680	COG0438	transferase activity, transferring glycosyl groups
DA819_RS03685	COG1247	-acetyltransferase
DA819_RS03785	COG0454	-acetyltransferase
DA819_RS03900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DA819_RS03980	COG4804	nuclease activity
DA819_RS04035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DA819_RS04210	COG1716	ATPase activity
DA819_RS04215	COG0363	glucosamine-6-phosphate deaminase activity
DA819_RS04225	COG1131	(ABC) transporter
DA819_RS04225	COG1716	ATPase activity
DA819_RS04225	COG0842	Transport permease protein
DA819_RS04230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS04250	COG2226	methyltransferase
DA819_RS04255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DA819_RS04260	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DA819_RS04265	COG0830	nickel cation binding
DA819_RS04295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA819_RS04295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DA819_RS04300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DA819_RS04330	COG1672	PFAM Archaeal ATPase
DA819_RS04330	COG2319	Wd-40 repeat
DA819_RS04335	COG1132	(ABC) transporter
DA819_RS04400	COG2010	Cytochrome c
DA819_RS04420	COG0617	tRNA 3'-terminal CCA addition
DA819_RS04450	COG0181	hydroxymethylbilane synthase activity
DA819_RS04485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DA819_RS04500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DA819_RS04540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DA819_RS04555	COG1216	Glycosyl transferase, family 2
DA819_RS04580	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DA819_RS04590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DA819_RS04605	COG2010	Cytochrome c
DA819_RS04620	COG1587	Uroporphyrinogen-III synthase
DA819_RS04640	COG0484	heat shock protein binding
DA819_RS04655	COG0067	glutamate synthase
DA819_RS04655	COG0069	glutamate synthase activity
DA819_RS04655	COG0070	glutamate synthase
DA819_RS04670	COG0316	Belongs to the HesB IscA family
DA819_RS04700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DA819_RS04705	COG1605	Chorismate mutase
DA819_RS04705	COG0077	Prephenate dehydratase
DA819_RS04715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DA819_RS04720	COG1530	ribonuclease E activity
DA819_RS04750	COG0436	Aminotransferase
DA819_RS04755	COG0436	Aminotransferase
DA819_RS04760	COG0436	Aminotransferase
DA819_RS04865	COG0724	RNA recognition motif
DA819_RS04870	COG0616	signal peptide processing
DA819_RS04890	COG0668	transmembrane transport
DA819_RS04895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DA819_RS04900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DA819_RS05000	COG0170	dolichyl monophosphate biosynthetic process
DA819_RS05010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA819_RS05025	COG1606	tRNA processing
DA819_RS05035	COG0484	heat shock protein binding
DA819_RS05050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DA819_RS05060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DA819_RS05065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DA819_RS05070	COG0837	glucose binding
DA819_RS05075	COG2373	Large extracellular alpha-helical protein
DA819_RS05085	COG1192	Involved in chromosome partitioning
DA819_RS05100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DA819_RS05110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DA819_RS05115	COG0494	nUDIX hydrolase
DA819_RS05120	COG0415	Belongs to the DNA photolyase family
DA819_RS05135	COG0515	serine threonine protein kinase
DA819_RS05135	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS05140	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS05140	COG0515	serine threonine protein kinase
DA819_RS05145	COG0515	serine threonine protein kinase
DA819_RS05145	COG2815	serine threonine protein kinase
DA819_RS05155	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS05155	COG0515	serine threonine protein kinase
DA819_RS05160	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS05160	COG0515	serine threonine protein kinase
DA819_RS05165	COG0515	serine threonine protein kinase
DA819_RS05165	COG3266	domain, Protein
DA819_RS05210	COG0640	Transcriptional regulator
DA819_RS05220	COG5002	protein histidine kinase activity
DA819_RS05245	COG2211	Major facilitator Superfamily
DA819_RS05265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DA819_RS05270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DA819_RS05330	COG3751	2OG-Fe(II) oxygenase superfamily
DA819_RS05335	COG3751	2OG-Fe(II) oxygenase superfamily
DA819_RS05345	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DA819_RS05355	COG2843	Capsule synthesis protein
DA819_RS05360	COG0676	glucose-6-phosphate 1-epimerase activity
DA819_RS05370	COG0191	fructose-bisphosphate aldolase activity
DA819_RS05405	COG0741	lytic transglycosylase activity
DA819_RS05430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DA819_RS05435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA819_RS05445	COG1131	(ABC) transporter
DA819_RS05470	COG2202	Pas domain
DA819_RS05470	COG2205	protein histidine kinase activity
DA819_RS05475	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DA819_RS05480	COG1234	tRNA 3'-trailer cleavage
DA819_RS05570	COG1674	ftsk spoiiie
DA819_RS05650	COG3259	Nickel-dependent hydrogenase
DA819_RS05655	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
DA819_RS05665	COG1151	hydroxylamine reductase activity
DA819_RS05675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DA819_RS05680	COG0298	carbon dioxide binding
DA819_RS05685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DA819_RS05685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DA819_RS05685	COG1013	pyruvate-flavodoxin oxidoreductase activity
DA819_RS05685	COG0674	pyruvate-flavodoxin oxidoreductase activity
DA819_RS05690	COG0167	dihydroorotate dehydrogenase activity
DA819_RS05700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA819_RS05710	COG0390	transport system, permease component
DA819_RS05735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DA819_RS05740	COG2205	protein histidine kinase activity
DA819_RS05820	COG0542	response to heat
DA819_RS05860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DA819_RS05865	COG0457	Tetratricopeptide repeat
DA819_RS05885	COG2198	Histidine kinase
DA819_RS05885	COG0784	Response regulator, receiver
DA819_RS05885	COG5002	protein histidine kinase activity
DA819_RS05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS05890	COG2205	protein histidine kinase activity
DA819_RS05915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS05935	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA819_RS05940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA819_RS05945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DA819_RS05950	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DA819_RS05965	COG2340	Cysteine-rich secretory protein family
DA819_RS06005	COG1074	ATP-dependent DNA helicase activity
DA819_RS06020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DA819_RS06025	COG0297	glycogen (starch) synthase activity
DA819_RS06185	COG0445	tRNA wobble uridine modification
DA819_RS06200	COG1215	transferase activity, transferring glycosyl groups
DA819_RS06320	COG0180	Tryptophanyl-tRNA synthetase
DA819_RS06325	COG0784	Response regulator, receiver
DA819_RS06325	COG2205	protein histidine kinase activity
DA819_RS06330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DA819_RS06340	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DA819_RS06350	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DA819_RS06365	COG1305	Transglutaminase-like
DA819_RS06375	COG3335	DDE superfamily endonuclease
DA819_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS06505	COG3850	Histidine kinase
DA819_RS06505	COG4999	Histidine kinase
DA819_RS06505	COG2205	protein histidine kinase activity
DA819_RS06505	COG3437	response regulator, receiver
DA819_RS06515	COG0492	ferredoxin-NADP+ reductase activity
DA819_RS06525	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS06530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DA819_RS06540	COG4636	protein conserved in cyanobacteria
DA819_RS06545	COG4636	protein conserved in cyanobacteria
DA819_RS06570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DA819_RS06585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA819_RS06590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA819_RS06610	COG0024	Methionine aminopeptidase
DA819_RS06615	COG0745	RESPONSE REGULATOR receiver
DA819_RS06660	COG3757	hydrolase, family 25
DA819_RS06665	COG2226	methyltransferase
DA819_RS06670	COG0492	ferredoxin-NADP+ reductase activity
DA819_RS06680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA819_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
DA819_RS06695	COG0179	Fumarylacetoacetate (FAA) hydrolase
DA819_RS06700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DA819_RS06705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DA819_RS06705	COG0519	Catalyzes the synthesis of GMP from XMP
DA819_RS06715	COG2239	Acts as a magnesium transporter
DA819_RS06725	COG1285	pathogenesis
DA819_RS06730	COG0366	Alpha amylase catalytic
DA819_RS06735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DA819_RS06745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DA819_RS06765	COG0745	RESPONSE REGULATOR receiver
DA819_RS06780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DA819_RS06785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DA819_RS06790	COG1058	Belongs to the CinA family
DA819_RS06790	COG1546	Belongs to the CinA family
DA819_RS06800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DA819_RS06835	COG1480	7TM receptor with intracellular HD hydrolase
DA819_RS06845	COG0495	leucyl-tRNA aminoacylation
DA819_RS06865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DA819_RS06875	COG0564	pseudouridine synthase activity
DA819_RS06915	COG0116	Belongs to the methyltransferase superfamily
DA819_RS06930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA819_RS06950	COG0123	including yeast histone deacetylase and acetoin utilization protein
DA819_RS06965	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DA819_RS06970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DA819_RS06985	COG0450	alkyl hydroperoxide reductase
DA819_RS06990	COG2133	pyrroloquinoline quinone binding
DA819_RS06995	COG2267	carboxylic ester hydrolase activity
DA819_RS07000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DA819_RS07065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DA819_RS07070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DA819_RS07075	COG3842	ATPase activity
DA819_RS07100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA819_RS07105	COG4999	Histidine kinase
DA819_RS07105	COG2205	protein histidine kinase activity
DA819_RS07105	COG3437	response regulator, receiver
DA819_RS07105	COG3850	Histidine kinase
DA819_RS07115	COG2205	protein histidine kinase activity
DA819_RS07130	COG0504	CTP synthase activity
DA819_RS07135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA819_RS07140	COG1196	nuclear chromosome segregation
DA819_RS07155	COG0653	protein targeting
DA819_RS07170	COG1715	Restriction endonuclease
DA819_RS07210	COG0024	Methionine aminopeptidase
DA819_RS07220	COG2202	Pas domain
DA819_RS07220	COG3920	Histidine kinase
DA819_RS07225	COG0673	inositol 2-dehydrogenase activity
DA819_RS07250	COG0675	Transposase, IS605 OrfB family
DA819_RS07275	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DA819_RS07285	COG1555	photosystem II stabilization
DA819_RS07305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DA819_RS07310	COG1217	gtp-binding protein TYPA
DA819_RS07320	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
DA819_RS07325	COG0589	response to stress
DA819_RS07345	COG3903	Transcriptional regulator
DA819_RS07345	COG2319	Wd-40 repeat
DA819_RS07390	COG2226	methyltransferase
DA819_RS07400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DA819_RS07405	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DA819_RS07415	COG0402	S-adenosylhomocysteine deaminase activity
DA819_RS07425	COG2911	Protein conserved in bacteria
DA819_RS07425	COG3266	domain, Protein
DA819_RS07425	COG1361	Conserved repeat domain
DA819_RS07440	COG1175	transmembrane transport
DA819_RS07445	COG0659	secondary active sulfate transmembrane transporter activity
DA819_RS07450	COG0659	secondary active sulfate transmembrane transporter activity
DA819_RS07465	COG1022	Amp-dependent synthetase and ligase
DA819_RS07475	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA819_RS07490	COG0523	cobalamin synthesis protein
DA819_RS07500	COG0302	gtp cyclohydrolase
DA819_RS07640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DA819_RS07680	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DA819_RS07705	COG0463	Glycosyl transferase, family 2
DA819_RS07705	COG1216	Glycosyl transferase, family 2
DA819_RS07810	COG0483	inositol monophosphate 1-phosphatase activity
DA819_RS07825	COG0517	IMP dehydrogenase activity
DA819_RS07825	COG0617	tRNA 3'-terminal CCA addition
DA819_RS07825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DA819_RS07855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DA819_RS07855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DA819_RS07860	COG1733	regulation of RNA biosynthetic process
DA819_RS07865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DA819_RS07865	COG0574	Belongs to the PEP-utilizing enzyme family
DA819_RS07945	COG0723	plastoquinol--plastocyanin reductase activity
DA819_RS07950	COG3258	Cytochrome c
DA819_RS07955	COG0596	Alpha beta hydrolase
DA819_RS08090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DA819_RS08100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DA819_RS08140	COG0003	Pfam Anion-transporting ATPase
DA819_RS08215	COG2052	Domain of unknown function (DUF370)
DA819_RS08220	COG0194	GDP metabolic process
DA819_RS08225	COG2304	oxidoreductase activity
DA819_RS08230	COG0740	serine-type endopeptidase activity
DA819_RS08235	COG0740	serine-type endopeptidase activity
DA819_RS08240	COG0740	serine-type endopeptidase activity
DA819_RS08245	COG0484	heat shock protein binding
DA819_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS08295	COG1132	(ABC) transporter
DA819_RS08310	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DA819_RS08310	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DA819_RS08320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DA819_RS08330	COG3266	domain, Protein
DA819_RS08330	COG0515	serine threonine protein kinase
DA819_RS08335	COG3659	wide pore channel activity
DA819_RS08350	COG0745	RESPONSE REGULATOR receiver
DA819_RS08365	COG1234	tRNA 3'-trailer cleavage
DA819_RS08370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DA819_RS08390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DA819_RS08395	COG0193	aminoacyl-tRNA hydrolase activity
DA819_RS08415	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS08425	COG0514	ATP-dependent DNA helicase (RecQ)
DA819_RS08430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DA819_RS08440	COG0163	prenyltransferase activity
DA819_RS08445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DA819_RS08460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA819_RS08465	COG0123	including yeast histone deacetylase and acetoin utilization protein
DA819_RS08470	COG0556	nucleotide-excision repair
DA819_RS08475	COG0534	Mate efflux family protein
DA819_RS08480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DA819_RS08545	COG1337	RAMP superfamily
DA819_RS08555	COG1332	CRISPR-associated RAMP protein, Csm5 family
DA819_RS08615	COG2304	oxidoreductase activity
DA819_RS08640	COG2815	serine threonine protein kinase
DA819_RS08640	COG0515	serine threonine protein kinase
DA819_RS08725	COG1518	maintenance of DNA repeat elements
DA819_RS08740	COG0497	DNA recombination
DA819_RS08745	COG0167	dihydroorotate dehydrogenase activity
DA819_RS08770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DA819_RS08775	COG0765	amino acid transport
DA819_RS08780	COG4597	amino acid ABC transporter
DA819_RS08785	COG3842	ATPase activity
DA819_RS08795	COG3239	Fatty acid desaturase
DA819_RS08985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA819_RS08990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DA819_RS08995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA819_RS08995	COG1116	anion transmembrane transporter activity
DA819_RS09000	COG1116	anion transmembrane transporter activity
DA819_RS09140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DA819_RS09140	COG0426	domain, Protein
DA819_RS09145	COG0426	domain, Protein
DA819_RS09145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DA819_RS09160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DA819_RS09185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DA819_RS09190	COG0742	ribosomal rna small subunit methyltransferase
DA819_RS09195	COG3956	TIGRFAM MazG family protein
DA819_RS09235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DA819_RS09245	COG0398	Pfam SNARE associated Golgi protein
DA819_RS09255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DA819_RS09265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS09270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA819_RS09275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS09280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DA819_RS09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA819_RS09305	COG0530	calcium, potassium:sodium antiporter activity
DA819_RS09310	COG0018	arginyl-trna synthetase
DA819_RS09365	COG2205	protein histidine kinase activity
DA819_RS09365	COG4999	Histidine kinase
DA819_RS09365	COG3437	response regulator, receiver
DA819_RS09365	COG3850	Histidine kinase
DA819_RS09370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS09370	COG2198	Histidine kinase
DA819_RS09370	COG0784	Response regulator, receiver
DA819_RS09370	COG2205	protein histidine kinase activity
DA819_RS09395	COG1490	D-aminoacyl-tRNA deacylase activity
DA819_RS09400	COG0523	cobalamin synthesis protein
DA819_RS09405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA819_RS09510	COG0010	Belongs to the arginase family
DA819_RS09515	COG0375	protein maturation
DA819_RS09530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DA819_RS09535	COG1116	anion transmembrane transporter activity
DA819_RS09610	COG0438	transferase activity, transferring glycosyl groups
DA819_RS09625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DA819_RS09650	COG0583	DNA-binding transcription factor activity
DA819_RS09835	COG0515	serine threonine protein kinase
DA819_RS09835	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS09845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS09875	COG1115	amino acid carrier protein
DA819_RS09890	COG4249	Peptidase C14 caspase catalytic subunit p20
DA819_RS09890	COG2319	Wd-40 repeat
DA819_RS09970	COG0515	serine threonine protein kinase
DA819_RS09995	COG0515	serine threonine protein kinase
DA819_RS10005	COG0515	serine threonine protein kinase
DA819_RS10015	COG0443	Heat shock 70 kDa protein
DA819_RS10040	COG0515	serine threonine protein kinase
DA819_RS10050	COG1845	cytochrome c oxidase, subunit III
DA819_RS10055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DA819_RS10070	COG0109	protoheme IX farnesyltransferase activity
DA819_RS10080	COG5001	Diguanylate cyclase
DA819_RS10080	COG3706	GGDEF domain
DA819_RS10080	COG2203	Gaf domain
DA819_RS10080	COG4251	negative regulation of phosphorylation
DA819_RS10085	COG4251	negative regulation of phosphorylation
DA819_RS10090	COG0784	Response regulator, receiver
DA819_RS10090	COG2205	protein histidine kinase activity
DA819_RS10090	COG2198	Histidine kinase
DA819_RS10095	COG5001	Diguanylate cyclase
DA819_RS10095	COG4251	negative regulation of phosphorylation
DA819_RS10095	COG3706	GGDEF domain
DA819_RS10095	COG2203	Gaf domain
DA819_RS10100	COG2319	Wd-40 repeat
DA819_RS10100	COG1672	PFAM Archaeal ATPase
DA819_RS10110	COG3659	wide pore channel activity
DA819_RS10165	COG0439	Biotin carboxylase
DA819_RS10215	COG2911	Protein conserved in bacteria
DA819_RS10215	COG3266	domain, Protein
DA819_RS10215	COG1361	Conserved repeat domain
DA819_RS10255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA819_RS10405	COG4585	Histidine kinase
DA819_RS10410	COG2197	response regulator
DA819_RS10420	COG1131	(ABC) transporter
DA819_RS10440	COG1074	ATP-dependent DNA helicase activity
DA819_RS10450	COG0515	serine threonine protein kinase
DA819_RS10450	COG3266	domain, Protein
DA819_RS10455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA819_RS10460	COG2208	phosphoserine phosphatase activity
DA819_RS10460	COG2770	Histidine kinase
DA819_RS10470	COG2217	Heavy metal translocating P-type atpase
DA819_RS10475	COG0505	Belongs to the CarA family
DA819_RS10485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA819_RS10510	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DA819_RS10575	COG4956	integral membrane protein (PIN domain superfamily)
DA819_RS10605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DA819_RS10610	COG0149	triose-phosphate isomerase activity
DA819_RS10640	COG0352	thiamine-phosphate diphosphorylase activity
DA819_RS10675	COG1088	dTDP-glucose 4,6-dehydratase activity
DA819_RS10685	COG2843	Capsule synthesis protein
DA819_RS10700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DA819_RS10715	COG1116	anion transmembrane transporter activity
DA819_RS10715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA819_RS10720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DA819_RS10735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DA819_RS10740	COG0511	ligase activity, forming carbon-carbon bonds
DA819_RS10765	COG3608	succinylglutamate desuccinylase aspartoacylase
DA819_RS10775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS10775	COG4191	Histidine kinase
DA819_RS10795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DA819_RS10800	COG0720	synthase
DA819_RS10850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DA819_RS10870	COG0405	Gamma-glutamyltransferase
DA819_RS10900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DA819_RS10905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DA819_RS10910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DA819_RS10920	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DA819_RS10935	COG1649	PFAM Uncharacterised BCR, COG1649
DA819_RS10940	COG1215	transferase activity, transferring glycosyl groups
DA819_RS10970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DA819_RS10975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DA819_RS10980	COG1136	(ABC) transporter
DA819_RS10980	COG0577	efflux transmembrane transporter activity
DA819_RS10995	COG2385	sporulation resulting in formation of a cellular spore
DA819_RS11000	COG2183	response to ionizing radiation
DA819_RS11015	COG0675	Transposase, IS605 OrfB family
DA819_RS11025	COG2267	carboxylic ester hydrolase activity
DA819_RS11035	COG3540	Alkaline phosphatase
DA819_RS11045	COG0596	Alpha beta hydrolase
DA819_RS11050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA819_RS11065	COG0572	uridine kinase
DA819_RS11095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DA819_RS11110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DA819_RS11120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DA819_RS11130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DA819_RS11150	COG0702	epimerase
DA819_RS11155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DA819_RS11175	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DA819_RS11180	COG2226	methyltransferase
DA819_RS11185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DA819_RS11200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DA819_RS11205	COG0052	Belongs to the universal ribosomal protein uS2 family
DA819_RS11285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS11290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DA819_RS11315	COG0285	dihydrofolate synthase activity
DA819_RS11330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DA819_RS11335	COG0133	tryptophan synthase activity
DA819_RS11380	COG0251	oxidation-reduction process
DA819_RS11395	COG1404	Belongs to the peptidase S8 family
DA819_RS11430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DA819_RS11435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DA819_RS11440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DA819_RS11445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DA819_RS11445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DA819_RS11455	COG0314	molybdopterin synthase activity
DA819_RS11460	COG1595	DNA-templated transcription, initiation
DA819_RS11485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DA819_RS11490	COG1983	PspC domain protein
DA819_RS11495	COG2081	HI0933 family
DA819_RS11585	COG0632	four-way junction helicase activity
DA819_RS11590	COG2814	Major facilitator Superfamily
DA819_RS11615	COG0758	DNA mediated transformation
DA819_RS11615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DA819_RS11620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DA819_RS11625	COG0859	PFAM glycosyl transferase family 9
DA819_RS11635	COG1968	undecaprenyl-diphosphatase activity
DA819_RS11650	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA819_RS11655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA819_RS11670	COG0596	Alpha beta hydrolase
DA819_RS11675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DA819_RS11680	COG0515	serine threonine protein kinase
DA819_RS11680	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS11705	COG0589	response to stress
DA819_RS11705	COG0475	glutathione-regulated potassium exporter activity
DA819_RS11710	COG0751	glycine-tRNA ligase activity
DA819_RS11720	COG0515	serine threonine protein kinase
DA819_RS11720	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS11740	COG1316	TRANSCRIPTIONal
DA819_RS11750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DA819_RS11780	COG1175	transmembrane transport
DA819_RS11790	COG4581	dead DEAH box helicase
DA819_RS11795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DA819_RS11805	COG0649	NAD binding
DA819_RS11810	COG0275	rRNA processing
DA819_RS11845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DA819_RS11900	COG1049	propionate catabolic process, 2-methylcitrate cycle
DA819_RS11920	COG0489	protein tyrosine kinase activity
DA819_RS11925	COG1596	polysaccharide export
DA819_RS11930	COG1053	succinate dehydrogenase
DA819_RS11930	COG3976	FMN-binding domain protein
DA819_RS11945	COG0312	modulator of DNA gyrase
DA819_RS11950	COG2010	Cytochrome c
DA819_RS11955	COG2203	Gaf domain
DA819_RS11955	COG5001	Diguanylate cyclase
DA819_RS11955	COG4251	negative regulation of phosphorylation
DA819_RS11955	COG3706	GGDEF domain
DA819_RS11965	COG0233	cytoplasmic translational termination
DA819_RS11970	COG0528	UMP kinase activity
DA819_RS11975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA819_RS11995	COG0010	Belongs to the arginase family
DA819_RS12005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA819_RS12040	COG0728	peptidoglycan biosynthetic process
DA819_RS12055	COG0318	PFAM AMP-dependent synthetase and ligase
DA819_RS12065	COG0574	Belongs to the PEP-utilizing enzyme family
DA819_RS12065	COG3848	Pyruvate phosphate dikinase
DA819_RS12075	COG0315	cyclic pyranopterin monophosphate synthase activity
DA819_RS12085	COG1252	NADH dehydrogenase
DA819_RS12140	COG4968	Prepilin-type N-terminal cleavage methylation domain
DA819_RS12220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DA819_RS12250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DA819_RS12250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DA819_RS12260	COG0793	Belongs to the peptidase S41A family
DA819_RS12265	COG0131	Imidazoleglycerol-phosphate dehydratase
DA819_RS12280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DA819_RS12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA819_RS12295	COG4372	Transposase
DA819_RS12330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS12355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DA819_RS12365	COG0840	transmembrane signaling receptor activity
DA819_RS12370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS12380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DA819_RS12385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DA819_RS12395	COG0792	nuclease activity
DA819_RS12415	COG0675	Transposase, IS605 OrfB family
DA819_RS12425	COG0572	uridine kinase
DA819_RS12435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DA819_RS12450	COG0583	DNA-binding transcription factor activity
DA819_RS12455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DA819_RS12460	COG1012	belongs to the aldehyde dehydrogenase family
DA819_RS12480	COG1254	Belongs to the acylphosphatase family
DA819_RS12485	COG0436	Aminotransferase
DA819_RS12490	COG0308	aminopeptidase N
DA819_RS12575	COG0339	signal peptide processing
DA819_RS12580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DA819_RS12580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DA819_RS12585	COG2814	Major facilitator Superfamily
DA819_RS12590	COG3852	Histidine kinase
DA819_RS12600	COG1215	transferase activity, transferring glycosyl groups
DA819_RS12640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DA819_RS12645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DA819_RS12665	COG3659	wide pore channel activity
DA819_RS12675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DA819_RS12680	COG1040	competence protein
DA819_RS12705	COG0686	Belongs to the AlaDH PNT family
DA819_RS12710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DA819_RS12715	COG0501	Belongs to the peptidase M48B family
DA819_RS12720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DA819_RS12845	COG0107	imidazoleglycerol-phosphate synthase activity
DA819_RS12850	COG1115	amino acid carrier protein
DA819_RS12895	COG0768	penicillin binding
DA819_RS12905	COG0772	Belongs to the SEDS family
DA819_RS12985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DA819_RS12990	COG1672	PFAM Archaeal ATPase
DA819_RS12995	COG0724	RNA recognition motif
DA819_RS13025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA819_RS13060	COG0513	Belongs to the DEAD box helicase family
DA819_RS13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA819_RS13075	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DA819_RS13080	COG0443	Heat shock 70 kDa protein
DA819_RS13085	COG0484	heat shock protein binding
DA819_RS13145	COG0165	Argininosuccinate lyase
DA819_RS13155	COG2208	phosphoserine phosphatase activity
DA819_RS13160	COG0552	protein localization to endoplasmic reticulum
DA819_RS13165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DA819_RS13190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DA819_RS13195	COG0588	phosphoglycerate mutase activity
DA819_RS13200	COG0784	Response regulator, receiver
DA819_RS13200	COG2205	protein histidine kinase activity
DA819_RS13225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DA819_RS13235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DA819_RS13255	COG0475	glutathione-regulated potassium exporter activity
DA819_RS13280	COG0440	acetolactate synthase activity
DA819_RS13290	COG2226	methyltransferase
DA819_RS13295	COG0189	ligase activity
DA819_RS13300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DA819_RS13315	COG1832	CoA-binding protein
DA819_RS13320	COG1131	(ABC) transporter
DA819_RS13330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DA819_RS13335	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DA819_RS13355	COG1361	Conserved repeat domain
DA819_RS13355	COG2911	Protein conserved in bacteria
DA819_RS13355	COG3266	domain, Protein
DA819_RS13410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DA819_RS13415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DA819_RS13455	COG1943	Transposase
DA819_RS13470	COG1575	Belongs to the MenA family. Type 1 subfamily
DA819_RS13475	COG2124	cytochrome p450
DA819_RS13485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DA819_RS13490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DA819_RS13495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DA819_RS13500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DA819_RS13515	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DA819_RS13520	COG0006	proline dipeptidase activity
DA819_RS13555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DA819_RS13575	COG0824	Thioesterase
DA819_RS13580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DA819_RS13660	COG0114	fumarate hydratase activity
DA819_RS13665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DA819_RS13675	COG3659	wide pore channel activity
DA819_RS13690	COG1840	ABC-type Fe3 transport system, periplasmic component
DA819_RS13700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DA819_RS13730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DA819_RS13740	COG0039	L-malate dehydrogenase activity
DA819_RS13770	COG0515	serine threonine protein kinase
DA819_RS13770	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS13775	COG0515	serine threonine protein kinase
DA819_RS13775	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS13785	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS13785	COG0515	serine threonine protein kinase
DA819_RS13800	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DA819_RS13810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DA819_RS13870	COG1160	GTP binding
DA819_RS13880	COG3264	Mechanosensitive ion channel
DA819_RS13880	COG1196	nuclear chromosome segregation
DA819_RS13890	COG4208	sulfate ABC transporter
DA819_RS13895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DA819_RS13900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DA819_RS13910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DA819_RS13920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA819_RS13925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DA819_RS13930	COG1045	serine acetyltransferase
DA819_RS13935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA819_RS13940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA819_RS13950	COG0045	succinate-CoA ligase (ADP-forming) activity
DA819_RS13950	COG1042	CoA-binding domain protein
DA819_RS13950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA819_RS13960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DA819_RS13985	COG2911	Protein conserved in bacteria
DA819_RS13985	COG3266	domain, Protein
DA819_RS13985	COG1361	Conserved repeat domain
DA819_RS13990	COG2226	methyltransferase
DA819_RS14000	COG0058	SHG alpha-glucan phosphorylase activity
DA819_RS14010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DA819_RS14025	COG3621	Patatin-like phospholipase
DA819_RS14045	COG2226	methyltransferase
DA819_RS14075	COG0670	Belongs to the BI1 family
DA819_RS14090	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DA819_RS14165	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DA819_RS14180	COG3266	domain, Protein
DA819_RS14180	COG0515	serine threonine protein kinase
DA819_RS14190	COG0515	serine threonine protein kinase
DA819_RS14210	COG1122	ATPase activity
DA819_RS14220	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DA819_RS14225	COG0310	cobalt ion transport
DA819_RS14230	COG1216	Glycosyl transferase, family 2
DA819_RS14235	COG0137	argininosuccinate synthase activity
DA819_RS14250	COG5322	oxidoreductase activity
DA819_RS14275	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DA819_RS14305	COG0395	ABC-type sugar transport system, permease component
DA819_RS14315	COG0438	transferase activity, transferring glycosyl groups
DA819_RS14315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DA819_RS14325	COG1454	alcohol dehydrogenase
DA819_RS14325	COG1012	belongs to the aldehyde dehydrogenase family
DA819_RS14330	COG0651	ATP synthesis coupled electron transport
DA819_RS14335	COG1006	Multisubunit Na H antiporter MnhC subunit
DA819_RS14340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA819_RS14370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA819_RS14395	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DA819_RS14400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DA819_RS14405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DA819_RS14415	COG5002	protein histidine kinase activity
DA819_RS14415	COG2205	protein histidine kinase activity
DA819_RS14415	COG0784	Response regulator, receiver
DA819_RS14455	COG0189	ligase activity
DA819_RS14455	COG4067	protein conserved in archaea
DA819_RS14480	COG1176	ABC-type spermidine putrescine transport system, permease component I
DA819_RS14490	COG1177	transmembrane transport
DA819_RS14500	COG0469	pyruvate kinase activity
DA819_RS14505	COG0305	Participates in initiation and elongation during chromosome replication
DA819_RS14505	COG1372	Participates in initiation and elongation during chromosome replication
DA819_RS14510	COG0359	binds to the 23S rRNA
DA819_RS14515	COG1126	abc transporter atp-binding protein
DA819_RS14530	COG1131	(ABC) transporter
DA819_RS14535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DA819_RS14550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA819_RS14555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA819_RS14595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DA819_RS14605	COG2252	PERMEase
DA819_RS14610	COG2203	Gaf domain
DA819_RS14615	COG0628	permease
DA819_RS14620	COG0697	spore germination
DA819_RS14625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA819_RS14635	COG0302	gtp cyclohydrolase
DA819_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS14645	COG0825	malonyl-CoA metabolic process
DA819_RS14655	COG0678	peroxiredoxin activity
DA819_RS14675	COG3266	domain, Protein
DA819_RS14675	COG0515	serine threonine protein kinase
DA819_RS14695	COG0515	serine threonine protein kinase
DA819_RS14695	COG2815	serine threonine protein kinase
DA819_RS14710	COG3937	granule-associated protein
DA819_RS14715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA819_RS14725	COG0631	protein serine/threonine phosphatase activity
DA819_RS14730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DA819_RS14760	COG1070	Carbohydrate kinase
DA819_RS14765	COG3409	Peptidoglycan-binding domain 1 protein
DA819_RS14765	COG3773	Cell wall hydrolase
DA819_RS14770	COG0151	Belongs to the GarS family
DA819_RS14775	COG5002	protein histidine kinase activity
DA819_RS14860	COG0429	hydrolase of the alpha beta-hydrolase fold
DA819_RS14865	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS14865	COG0515	serine threonine protein kinase
DA819_RS14870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DA819_RS14965	COG0702	epimerase
DA819_RS15035	COG1132	(ABC) transporter
DA819_RS15060	COG0463	Glycosyl transferase, family 2
DA819_RS15065	COG3118	belongs to the thioredoxin family
DA819_RS15070	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS15075	COG0459	protein refolding
DA819_RS15080	COG0745	RESPONSE REGULATOR receiver
DA819_RS15085	COG0745	RESPONSE REGULATOR receiver
DA819_RS15085	COG2205	protein histidine kinase activity
DA819_RS15085	COG4191	Histidine kinase
DA819_RS15105	COG0571	ribonuclease III activity
DA819_RS15115	COG4245	von Willebrand factor, type A
DA819_RS15125	COG5001	Diguanylate cyclase
DA819_RS15125	COG3706	GGDEF domain
DA819_RS15125	COG2203	Gaf domain
DA819_RS15125	COG4251	negative regulation of phosphorylation
DA819_RS15150	COG0840	transmembrane signaling receptor activity
DA819_RS15155	COG0142	geranyltranstransferase activity
DA819_RS15175	COG0602	queuosine metabolic process
DA819_RS15180	COG0023	Translation Initiation Factor
DA819_RS15210	COG1496	oxidoreductase activity
DA819_RS15220	COG0739	heme binding
DA819_RS15245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DA819_RS15250	COG0745	RESPONSE REGULATOR receiver
DA819_RS15270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS15300	COG2954	triphosphatase activity
DA819_RS15320	COG2197	response regulator
DA819_RS15330	COG0124	histidyl-tRNA synthetase
DA819_RS15340	COG2319	Wd-40 repeat
DA819_RS15340	COG4249	Peptidase C14 caspase catalytic subunit p20
DA819_RS15340	COG4249	Peptidase C14 caspase catalytic subunit p20
DA819_RS15340	COG2319	Wd-40 repeat
DA819_RS15350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DA819_RS15355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DA819_RS15365	COG2319	Wd-40 repeat
DA819_RS15365	COG4249	Peptidase C14 caspase catalytic subunit p20
DA819_RS15375	COG2205	protein histidine kinase activity
DA819_RS15390	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS15390	COG0515	serine threonine protein kinase
DA819_RS15395	COG0072	phenylalanine-tRNA ligase activity
DA819_RS15395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA819_RS15435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DA819_RS15450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DA819_RS15465	COG2027	D-alanyl-D-alanine carboxypeptidase
DA819_RS15480	COG0416	fatty acid biosynthetic process
DA819_RS15485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DA819_RS15490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DA819_RS15495	COG5002	protein histidine kinase activity
DA819_RS15630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DA819_RS15645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DA819_RS15660	COG3335	DDE superfamily endonuclease
DA819_RS15730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA819_RS15840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DA819_RS15920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DA819_RS15925	COG0436	Aminotransferase
DA819_RS15930	COG1619	proteins homologs of microcin C7 resistance protein MccF
DA819_RS15935	COG0384	phenazine biosynthesis protein PhzF
DA819_RS15940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DA819_RS15985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DA819_RS15990	COG0829	nickel cation binding
DA819_RS15995	COG0831	urea catabolic process
DA819_RS16000	COG0832	Belongs to the urease beta subunit family
DA819_RS16005	COG0804	urea catabolic process
DA819_RS16010	COG3706	GGDEF domain
DA819_RS16035	COG1649	PFAM Uncharacterised BCR, COG1649
DA819_RS16050	COG1794	racemase activity, acting on amino acids and derivatives
DA819_RS16095	COG0516	GMP reductase activity
DA819_RS16100	COG3118	belongs to the thioredoxin family
DA819_RS16110	COG0745	RESPONSE REGULATOR receiver
DA819_RS16115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DA819_RS16145	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DA819_RS16160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DA819_RS16165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DA819_RS16165	COG0140	phosphoribosyl-ATP diphosphatase activity
DA819_RS16190	COG2308	Evidence 4 Homologs of previously reported genes of
DA819_RS16200	COG0540	Belongs to the ATCase OTCase family
DA819_RS16225	COG1132	(ABC) transporter
DA819_RS16235	COG0443	Heat shock 70 kDa protein
DA819_RS16255	COG0800	Aldolase
DA819_RS16260	COG0435	Glutathione S-transferase
DA819_RS16290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DA819_RS16295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DA819_RS16310	COG0747	negative chemotaxis
DA819_RS16315	COG1691	(AIR) carboxylase
DA819_RS16475	COG0159	tryptophan synthase activity
DA819_RS16505	COG0656	L-ascorbic acid biosynthetic process
DA819_RS16555	COG0450	alkyl hydroperoxide reductase
DA819_RS16560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DA819_RS16570	COG0542	response to heat
DA819_RS16575	COG0346	lactoylglutathione lyase activity
DA819_RS16620	COG1473	amidohydrolase
DA819_RS16730	COG3842	ATPase activity
DA819_RS16755	COG0330	HflC and HflK could
DA819_RS16770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DA819_RS16775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DA819_RS16780	COG0515	serine threonine protein kinase
DA819_RS16780	COG2815	serine threonine protein kinase
DA819_RS16795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DA819_RS16805	COG0217	transcriptional regulatory protein
DA819_RS16815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DA819_RS16815	COG3264	Mechanosensitive ion channel
DA819_RS16905	COG0668	transmembrane transport
DA819_RS16910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DA819_RS16935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DA819_RS16945	COG1376	ErfK ybiS ycfS ynhG family protein
DA819_RS16950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA819_RS16960	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS16960	COG0515	serine threonine protein kinase
DA819_RS17105	COG0788	formyltetrahydrofolate deformylase activity
DA819_RS17120	COG2205	protein histidine kinase activity
DA819_RS17160	COG0577	efflux transmembrane transporter activity
DA819_RS17160	COG1136	(ABC) transporter
DA819_RS17165	COG0577	efflux transmembrane transporter activity
DA819_RS17165	COG1136	(ABC) transporter
DA819_RS17175	COG0564	pseudouridine synthase activity
DA819_RS17180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DA819_RS17195	COG1597	lipid kinase activity
DA819_RS17200	COG0419	ATPase involved in DNA repair
DA819_RS17210	COG0058	SHG alpha-glucan phosphorylase activity
DA819_RS17215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DA819_RS17220	COG0251	oxidation-reduction process
DA819_RS17230	COG0251	oxidation-reduction process
DA819_RS17240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DA819_RS17240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DA819_RS17285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA819_RS17290	COG2226	methyltransferase
DA819_RS17295	COG3706	GGDEF domain
DA819_RS17315	COG0488	(ABC) transporter
DA819_RS17320	COG0784	Response regulator, receiver
DA819_RS17320	COG2205	protein histidine kinase activity
DA819_RS17325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA819_RS17340	COG1525	nuclease
DA819_RS17350	COG0175	sulfate reduction
DA819_RS17395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DA819_RS17405	COG0463	Glycosyl transferase, family 2
DA819_RS17445	COG0784	Response regulator, receiver
DA819_RS17445	COG2205	protein histidine kinase activity
DA819_RS17450	COG0126	phosphoglycerate kinase activity
DA819_RS17455	COG0589	response to stress
DA819_RS17465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DA819_RS17490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DA819_RS17520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DA819_RS17530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DA819_RS17535	COG0284	orotidine-5'-phosphate decarboxylase activity
DA819_RS17600	COG3344	reverse transcriptase
DA819_RS17745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DA819_RS17745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DA819_RS17755	COG1994	Peptidase M50
DA819_RS17755	COG0517	IMP dehydrogenase activity
DA819_RS17760	COG0095	Lipoate-protein ligase
DA819_RS17825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DA819_RS17850	COG5002	protein histidine kinase activity
DA819_RS17900	COG0312	modulator of DNA gyrase
DA819_RS17910	COG1704	LemA family
DA819_RS17915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DA819_RS18050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DA819_RS18055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA819_RS18060	COG4243	Vitamin k epoxide reductase
DA819_RS18080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS18145	COG2264	protein methyltransferase activity
DA819_RS18150	COG0189	ligase activity
DA819_RS18160	COG0436	Aminotransferase
DA819_RS18165	COG0371	Dehydrogenase
DA819_RS18210	COG2274	protein secretion by the type I secretion system
DA819_RS18225	COG1216	Glycosyl transferase, family 2
DA819_RS18250	COG0640	Transcriptional regulator
DA819_RS18340	COG0745	RESPONSE REGULATOR receiver
DA819_RS18350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DA819_RS18360	COG4953	penicillin-binding protein 1C
DA819_RS18375	COG0850	regulation of cytokinetic process
DA819_RS18380	COG2894	cell division
DA819_RS18385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DA819_RS18405	COG1403	HNH endonuclease
DA819_RS18415	COG2337	Toxic component of a toxin-antitoxin (TA) module
DA819_RS18430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DA819_RS18435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DA819_RS18440	COG0443	Heat shock 70 kDa protein
DA819_RS18450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DA819_RS18470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DA819_RS18500	COG3769	mannosylglycerate metabolic process
DA819_RS18505	COG0750	zinc metalloprotease
DA819_RS18510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DA819_RS18515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DA819_RS18530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DA819_RS18555	COG4243	Vitamin k epoxide reductase
DA819_RS18560	COG0434	BtpA family
DA819_RS18655	COG0438	transferase activity, transferring glycosyl groups
DA819_RS18655	COG1216	Glycosyl transferase, family 2
DA819_RS18680	COG1615	UPF0182 protein
DA819_RS18695	COG3854	ATPases associated with a variety of cellular activities
DA819_RS18715	COG5278	phosphoserine phosphatase activity
DA819_RS18715	COG0840	transmembrane signaling receptor activity
DA819_RS18720	COG0643	Histidine kinase
DA819_RS18720	COG0784	Response regulator, receiver
DA819_RS18720	COG2198	Histidine kinase
DA819_RS18725	COG2201	protein-glutamate methylesterase activity
DA819_RS18730	COG0745	RESPONSE REGULATOR receiver
DA819_RS18740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA819_RS18755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DA819_RS18775	COG0701	Predicted permease
DA819_RS18805	COG3335	DDE superfamily endonuclease
DA819_RS18900	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DA819_RS18950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DA819_RS18955	COG0525	valine-tRNA ligase activity
DA819_RS18965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DA819_RS18975	COG2205	protein histidine kinase activity
DA819_RS18975	COG3437	response regulator, receiver
DA819_RS18975	COG3850	Histidine kinase
DA819_RS18975	COG4999	Histidine kinase
DA819_RS18995	COG1160	GTP binding
DA819_RS19000	COG1090	epimerase
DA819_RS19010	COG0297	glycogen (starch) synthase activity
DA819_RS19015	COG0799	negative regulation of ribosome biogenesis
DA819_RS19040	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DA819_RS19050	COG1116	anion transmembrane transporter activity
DA819_RS19050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA819_RS19055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DA819_RS19060	COG1116	anion transmembrane transporter activity
DA819_RS19060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA819_RS19165	COG4279	zinc finger
DA819_RS19175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DA819_RS19190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DA819_RS19190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DA819_RS19195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DA819_RS19215	COG2203	Gaf domain
DA819_RS19215	COG3706	GGDEF domain
DA819_RS19215	COG4251	negative regulation of phosphorylation
DA819_RS19215	COG5001	Diguanylate cyclase
DA819_RS19250	COG0824	Thioesterase
DA819_RS19260	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DA819_RS19275	COG0457	Tetratricopeptide repeat
DA819_RS19275	COG0463	Glycosyl transferase, family 2
DA819_RS19330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DA819_RS19385	COG2211	Major facilitator Superfamily
DA819_RS19400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA819_RS19410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DA819_RS19455	COG1459	type II secretion system
DA819_RS19480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DA819_RS19485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DA819_RS19490	COG0443	Heat shock 70 kDa protein
DA819_RS19495	COG0484	heat shock protein binding
DA819_RS19505	COG1162	GTPase activity
DA819_RS19515	COG0243	molybdopterin cofactor binding
DA819_RS19520	COG2223	nitrite transmembrane transporter activity
DA819_RS19530	COG0402	S-adenosylhomocysteine deaminase activity
DA819_RS19535	COG1596	polysaccharide export
DA819_RS19585	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS19595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DA819_RS19615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DA819_RS19710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA819_RS19715	COG0719	Fe-S assembly protein
DA819_RS19720	COG0396	ATPase activity
DA819_RS19725	COG0719	Fe-S assembly protein
DA819_RS19740	COG2255	four-way junction helicase activity
DA819_RS19840	COG0460	homoserine dehydrogenase
DA819_RS19845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS19865	COG1295	ribonuclease BN
DA819_RS19895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DA819_RS19900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA819_RS19930	COG0484	heat shock protein binding
DA819_RS19940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DA819_RS19945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DA819_RS19950	COG0019	diaminopimelate decarboxylase activity
DA819_RS19960	COG0542	response to heat
DA819_RS19970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DA819_RS19975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DA819_RS19980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DA819_RS20010	COG1473	amidohydrolase
DA819_RS20025	COG0601	transmembrane transport
DA819_RS20030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DA819_RS20065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DA819_RS20080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DA819_RS20090	COG0521	Mo-molybdopterin cofactor biosynthetic process
DA819_RS20095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DA819_RS20100	COG2154	pterin-4-alpha-carbinolamine dehydratase
DA819_RS20115	COG2890	protein-(glutamine-N5) methyltransferase activity
DA819_RS20130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DA819_RS20150	COG1260	myo-inositol-1-phosphate synthase
DA819_RS20210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DA819_RS20250	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DA819_RS20275	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DA819_RS20280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA819_RS20285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DA819_RS20290	COG0395	ABC-type sugar transport system, permease component
DA819_RS20320	COG0489	protein tyrosine kinase activity
DA819_RS20325	COG0408	coproporphyrinogen oxidase activity
DA819_RS20355	COG0739	heme binding
DA819_RS20360	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DA819_RS20375	COG0587	DNA-directed DNA polymerase activity
DA819_RS20380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DA819_RS20390	COG1842	Phage shock protein A
DA819_RS20395	COG1842	Phage shock protein A
DA819_RS20410	COG2197	response regulator
DA819_RS20430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DA819_RS20455	COG0842	Transport permease protein
DA819_RS20455	COG1131	(ABC) transporter
DA819_RS20455	COG1716	ATPase activity
DA819_RS20485	COG1215	transferase activity, transferring glycosyl groups
DA819_RS20495	COG0110	maltose O-acetyltransferase activity
DA819_RS20530	COG0457	Tetratricopeptide repeat
DA819_RS20560	COG0642	Histidine kinase
DA819_RS20570	COG1725	Transcriptional regulator
DA819_RS20575	COG0412	Dienelactone hydrolase
DA819_RS20580	COG0539	negative regulation of cytoplasmic translation
DA819_RS20585	COG2971	BadF BadG BcrA BcrD
DA819_RS20595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA819_RS20610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DA819_RS20655	COG3266	domain, Protein
DA819_RS20655	COG0515	serine threonine protein kinase
DA819_RS20755	COG0542	response to heat
DA819_RS20780	COG5002	protein histidine kinase activity
DA819_RS20790	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DA819_RS20790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA819_RS20810	COG2217	Heavy metal translocating P-type atpase
DA819_RS20820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DA819_RS20830	COG1413	lyase activity
DA819_RS20835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DA819_RS20840	COG0237	dephospho-CoA kinase activity
DA819_RS20860	COG0601	transmembrane transport
DA819_RS20870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DA819_RS20875	COG0629	single-stranded DNA binding
DA819_RS20880	COG5002	protein histidine kinase activity
DA819_RS20900	COG0321	lipoyl(octanoyl) transferase activity
DA819_RS20980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DA819_RS21055	COG2192	nodulation
DA819_RS21075	COG0277	FAD linked oxidase domain protein
DA819_RS21075	COG0247	lactate metabolic process
DA819_RS21085	COG0740	serine-type endopeptidase activity
DA819_RS21095	COG0557	exoribonuclease II activity
DA819_RS21105	COG0776	regulation of translation
DA819_RS21110	COG1429	ligase activity, forming nitrogen-metal bonds
DA819_RS21115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DA819_RS21120	COG0569	domain protein
DA819_RS21135	COG0501	Belongs to the peptidase M48B family
DA819_RS21145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DA819_RS21150	COG3266	domain, Protein
DA819_RS21150	COG2911	Protein conserved in bacteria
DA819_RS21150	COG1361	Conserved repeat domain
DA819_RS21175	COG1216	Glycosyl transferase, family 2
DA819_RS21175	COG0463	Glycosyl transferase, family 2
DA819_RS21215	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
DA819_RS21220	COG0438	transferase activity, transferring glycosyl groups
DA819_RS21235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DA819_RS21285	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DA819_RS21290	COG0375	protein maturation
DA819_RS21295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DA819_RS21300	COG0205	6-phosphofructokinase activity
DA819_RS21310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DA819_RS21425	COG1702	phosphate starvation-inducible protein PhoH
DA819_RS21435	COG1837	Belongs to the UPF0109 family
DA819_RS21440	COG0228	four-way junction DNA binding
DA819_RS21445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DA819_RS21460	COG1122	ATPase activity
DA819_RS21515	COG0517	IMP dehydrogenase activity
DA819_RS21515	COG0516	GMP reductase activity
DA819_RS21530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DA819_RS21550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA819_RS21570	COG0215	cysteine-tRNA ligase activity
DA819_RS21580	COG0523	cobalamin synthesis protein
DA819_RS21585	COG2166	iron-sulfur cluster assembly
DA819_RS21590	COG0113	porphobilinogen synthase activity
DA819_RS21610	COG0004	ammonium transporteR
DA819_RS21615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DA819_RS21630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DA819_RS21670	COG0596	Alpha beta hydrolase
DA819_RS21680	COG0538	isocitrate dehydrogenase activity
DA819_RS21685	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DA819_RS21690	COG2197	response regulator
DA819_RS21695	COG0303	'Molybdopterin
DA819_RS21705	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DA819_RS21740	COG0784	Response regulator, receiver
DA819_RS21740	COG2198	Histidine kinase
DA819_RS21740	COG2205	protein histidine kinase activity
DA819_RS21750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DA819_RS21760	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DA819_RS21785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DA819_RS21785	COG0512	Glutamine amidotransferase of anthranilate synthase
DA819_RS21790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DA819_RS21795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DA819_RS21890	COG1045	serine acetyltransferase
DA819_RS21910	COG0644	oxidoreductase
DA819_RS21915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DA819_RS21920	COG3536	Protein conserved in bacteria
DA819_RS21960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DA819_RS21970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DA819_RS22005	COG3335	DDE superfamily endonuclease
DA819_RS22055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DA819_RS22065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA819_RS22070	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DA819_RS22095	COG0612	Peptidase, M16
DA819_RS22100	COG0612	Peptidase, M16
DA819_RS22105	COG1309	transcriptional regulator
DA819_RS22190	COG1666	GTP binding
DA819_RS22335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DA819_RS22370	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DA819_RS22570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DA819_RS22635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DA819_RS22660	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DA819_RS22780	COG2066	Belongs to the glutaminase family
DA819_RS22785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DA819_RS22850	COG0589	response to stress
DA819_RS22875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DA819_RS22895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DA819_RS22900	COG0148	phosphopyruvate hydratase activity
DA819_RS22910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DA819_RS22915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DA819_RS22940	COG0134	indole-3-glycerol-phosphate synthase activity
DA819_RS22975	COG1196	nuclear chromosome segregation
DA819_RS22985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA819_RS23010	COG0745	RESPONSE REGULATOR receiver
DA819_RS23020	COG5002	protein histidine kinase activity
DA819_RS23035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA819_RS23050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA819_RS23065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA819_RS23125	COG2319	Wd-40 repeat
DA819_RS23125	COG3903	Transcriptional regulator
DA819_RS23130	COG1404	Belongs to the peptidase S8 family
DA819_RS23150	COG2211	Major facilitator Superfamily
DA819_RS23155	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
DA819_RS23160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA819_RS23160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA819_RS23170	COG2226	methyltransferase
DA819_RS23195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DA819_RS23220	COG0484	heat shock protein binding
DA819_RS23245	COG0488	(ABC) transporter
DA819_RS23250	COG2204	response regulator
DA819_RS23255	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DA819_RS23260	COG0254	rRNA binding
DA819_RS23265	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DA819_RS23270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DA819_RS23275	COG0101	tRNA pseudouridine synthase activity
DA819_RS23280	COG0203	ribosomal protein L17
DA819_RS23285	COG0202	RNA polymerase activity
DA819_RS23290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DA819_RS23295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DA819_RS23300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DA819_RS23305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DA819_RS23310	COG0563	adenylate kinase activity
DA819_RS23315	COG0201	protein transport
DA819_RS23320	COG0200	Binds to the 23S rRNA
DA819_RS23325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DA819_RS23330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DA819_RS23335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DA819_RS23340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DA819_RS23345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DA819_RS23350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DA819_RS23355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DA819_RS23360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DA819_RS23365	COG0255	Belongs to the universal ribosomal protein uL29 family
DA819_RS23370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DA819_RS23375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DA819_RS23380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DA819_RS23385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DA819_RS23390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DA819_RS23395	COG0089	rRNA binding
DA819_RS23400	COG0088	Forms part of the polypeptide exit tunnel
DA819_RS23405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DA819_RS23420	COG5002	protein histidine kinase activity
DA819_RS23440	COG2850	peptidyl-arginine hydroxylation
DA819_RS23470	COG0463	Glycosyl transferase, family 2
DA819_RS23475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DA819_RS23485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DA819_RS23490	COG3273	potassium ion transport
DA819_RS23490	COG0471	metal ion transport
DA819_RS23525	COG0745	RESPONSE REGULATOR receiver
DA819_RS23535	COG0138	bifunctional purine biosynthesis protein purh
DA819_RS23540	COG0328	RNA-DNA hybrid ribonuclease activity
DA819_RS23545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DA819_RS23555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DA819_RS23565	COG3118	belongs to the thioredoxin family
DA819_RS23575	COG0583	DNA-binding transcription factor activity
DA819_RS23580	COG0583	DNA-binding transcription factor activity
DA819_RS23585	COG0515	serine threonine protein kinase
DA819_RS23595	COG0675	Transposase, IS605 OrfB family
DA819_RS23630	COG0667	Aldo Keto reductase
DA819_RS23640	COG0307	riboflavin synthase, alpha
DA819_RS23645	COG2885	chlorophyll binding
DA819_RS23650	COG2885	chlorophyll binding
DA819_RS23660	COG0596	Alpha beta hydrolase
DA819_RS23670	COG0121	glutamine amidotransferase
DA819_RS23690	COG1073	alpha beta
DA819_RS23695	COG0509	glycine decarboxylation via glycine cleavage system
DA819_RS23700	COG1191	sigma factor activity
DA819_RS23730	COG0857	belongs to the CobB CobQ family
DA819_RS23745	COG1215	transferase activity, transferring glycosyl groups
DA819_RS23750	COG0045	succinate-CoA ligase (ADP-forming) activity
DA819_RS23755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DA819_RS23760	COG0415	Belongs to the DNA photolyase family
DA819_RS23845	COG0589	response to stress
DA819_RS23845	COG0475	glutathione-regulated potassium exporter activity
DA819_RS23865	COG0336	Belongs to the RNA methyltransferase TrmD family
DA819_RS23870	COG4242	Belongs to the peptidase S51 family
DA819_RS23875	COG0189	ligase activity
DA819_RS23875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DA819_RS23890	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DA819_RS23895	COG3409	Peptidoglycan-binding domain 1 protein
DA819_RS23935	COG1214	PFAM Peptidase M22, glycoprotease
DA819_RS23970	COG0515	serine threonine protein kinase
DA819_RS23970	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS23980	COG2203	Gaf domain
DA819_RS23980	COG3706	GGDEF domain
DA819_RS23980	COG4251	negative regulation of phosphorylation
DA819_RS23980	COG5001	Diguanylate cyclase
DA819_RS23985	COG0617	tRNA 3'-terminal CCA addition
DA819_RS24005	COG0784	Response regulator, receiver
DA819_RS24020	COG0840	transmembrane signaling receptor activity
DA819_RS24025	COG0643	Histidine kinase
DA819_RS24025	COG0784	Response regulator, receiver
DA819_RS24025	COG2198	Histidine kinase
DA819_RS24070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS24100	COG3706	GGDEF domain
DA819_RS24100	COG4251	negative regulation of phosphorylation
DA819_RS24100	COG5001	Diguanylate cyclase
DA819_RS24100	COG2203	Gaf domain
DA819_RS24110	COG0791	NLP P60 protein
DA819_RS24135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DA819_RS24140	COG0424	maF-like protein
DA819_RS24170	COG0154	amidase activity
DA819_RS24180	COG1127	ABC transporter
DA819_RS24185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DA819_RS24210	COG0612	Peptidase, M16
DA819_RS24225	COG0848	biopolymer transport protein
DA819_RS24230	COG0811	peptide transport
DA819_RS24235	COG1492	cobalamin metabolic process
DA819_RS24245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA819_RS24295	COG0724	RNA recognition motif
DA819_RS24305	COG0737	Belongs to the 5'-nucleotidase family
DA819_RS24310	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DA819_RS24315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DA819_RS24320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DA819_RS24330	COG0483	inositol monophosphate 1-phosphatase activity
DA819_RS24340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DA819_RS24360	COG0436	Aminotransferase
DA819_RS24365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DA819_RS24395	COG0195	Participates in both transcription termination and antitermination
DA819_RS24400	COG0779	Required for maturation of 30S ribosomal subunits
DA819_RS24410	COG1216	Glycosyl transferase, family 2
DA819_RS24415	COG0360	Binds together with S18 to 16S ribosomal RNA
DA819_RS24430	COG1776	CheC inhibitor of MCP methylation
DA819_RS24435	COG2201	protein-glutamate methylesterase activity
DA819_RS24445	COG0446	pyridine nucleotide-disulphide oxidoreductase
DA819_RS24450	COG0579	oxidoreductase
DA819_RS24460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DA819_RS24465	COG1121	(ABC) transporter
DA819_RS24475	COG0557	exoribonuclease II activity
DA819_RS24480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DA819_RS24485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DA819_RS24530	COG0436	Aminotransferase
DA819_RS24535	COG3118	belongs to the thioredoxin family
DA819_RS24565	COG1494	fructose-1,6-bisphosphatase
DA819_RS24570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DA819_RS24575	COG0525	valine-tRNA ligase activity
DA819_RS24585	COG1672	PFAM Archaeal ATPase
DA819_RS24585	COG2319	Wd-40 repeat
DA819_RS24590	COG1672	PFAM Archaeal ATPase
DA819_RS24590	COG2319	Wd-40 repeat
DA819_RS24595	COG0009	L-threonylcarbamoyladenylate synthase
DA819_RS24600	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DA819_RS24605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DA819_RS24610	COG1850	ribulose-bisphosphate carboxylase activity
DA819_RS24615	COG0235	Class ii aldolase
DA819_RS24620	COG2082	Precorrin-8x methylmutase
DA819_RS24630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DA819_RS24650	COG0444	Belongs to the ABC transporter superfamily
DA819_RS24655	COG4608	Belongs to the ABC transporter superfamily
DA819_RS24670	COG0657	acetylesterase activity
DA819_RS24680	COG3001	Fructosamine kinase
DA819_RS24695	COG2949	membrane
DA819_RS24705	COG0157	Belongs to the NadC ModD family
DA819_RS24715	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DA819_RS24720	COG1216	Glycosyl transferase, family 2
DA819_RS24730	COG1132	(ABC) transporter
DA819_RS24735	COG0438	transferase activity, transferring glycosyl groups
DA819_RS24750	COG0438	transferase activity, transferring glycosyl groups
DA819_RS24755	COG1216	Glycosyl transferase, family 2
DA819_RS24765	COG0438	transferase activity, transferring glycosyl groups
DA819_RS24770	COG0438	transferase activity, transferring glycosyl groups
DA819_RS24775	COG1216	Glycosyl transferase, family 2
DA819_RS24800	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DA819_RS24810	COG0515	serine threonine protein kinase
DA819_RS24810	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS24820	COG2205	protein histidine kinase activity
DA819_RS24820	COG0784	Response regulator, receiver
DA819_RS24830	COG3842	ATPase activity
DA819_RS24845	COG1653	transport
DA819_RS24850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DA819_RS24855	COG2076	Multidrug Resistance protein
DA819_RS24880	COG0515	serine threonine protein kinase
DA819_RS24880	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS24885	COG2205	protein histidine kinase activity
DA819_RS24885	COG0784	Response regulator, receiver
DA819_RS24900	COG1252	NADH dehydrogenase
DA819_RS24905	COG0802	atpase or kinase
DA819_RS24935	COG1136	(ABC) transporter
DA819_RS24955	COG0713	ATP synthesis coupled electron transport
DA819_RS24960	COG0839	Belongs to the complex I subunit 6 family
DA819_RS24965	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS24970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DA819_RS24980	COG0372	Belongs to the citrate synthase family
DA819_RS24985	COG2062	phosphohistidine phosphatase, SixA
DA819_RS24995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DA819_RS25005	COG0612	Peptidase, M16
DA819_RS25030	COG0135	phosphoribosylanthranilate isomerase activity
DA819_RS25045	COG0358	DNA primase activity
DA819_RS25055	COG4249	Peptidase C14 caspase catalytic subunit p20
DA819_RS25055	COG2319	Wd-40 repeat
DA819_RS25085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DA819_RS25100	COG1215	transferase activity, transferring glycosyl groups
DA819_RS25120	COG2270	Major facilitator Superfamily
DA819_RS25130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DA819_RS25140	COG5001	Diguanylate cyclase
DA819_RS25140	COG4251	negative regulation of phosphorylation
DA819_RS25140	COG3706	GGDEF domain
DA819_RS25140	COG2203	Gaf domain
DA819_RS25145	COG5001	Diguanylate cyclase
DA819_RS25145	COG3300	MHYT domain
DA819_RS25155	COG0745	RESPONSE REGULATOR receiver
DA819_RS25180	COG2205	protein histidine kinase activity
DA819_RS25180	COG0784	Response regulator, receiver
DA819_RS25180	COG5002	protein histidine kinase activity
DA819_RS25185	COG0589	response to stress
DA819_RS25190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DA819_RS25195	COG0268	Binds directly to 16S ribosomal RNA
DA819_RS25200	COG0084	hydrolase, TatD family'
DA819_RS25205	COG0085	RNA polymerase activity
DA819_RS25210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DA819_RS25215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DA819_RS25230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA819_RS25285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DA819_RS25290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DA819_RS25295	COG0047	phosphoribosylformylglycinamidine synthase activity
DA819_RS25325	COG3320	Male sterility
DA819_RS25325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA819_RS25330	COG0156	8-amino-7-oxononanoate synthase activity
DA819_RS25335	COG1032	radical SAM domain protein
DA819_RS25350	COG0419	ATPase involved in DNA repair
DA819_RS25360	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DA819_RS25395	COG0129	dihydroxy-acid dehydratase activity
DA819_RS25420	COG3659	wide pore channel activity
DA819_RS25425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DA819_RS25435	COG0542	response to heat
DA819_RS25465	COG2217	Heavy metal translocating P-type atpase
DA819_RS25470	COG1597	lipid kinase activity
DA819_RS25470	COG1803	Methylglyoxal synthase
DA819_RS25475	COG1253	flavin adenine dinucleotide binding
DA819_RS25645	COG1475	DNA binding
DA819_RS25650	COG1716	ATPase activity
DA819_RS25650	COG0842	Transport permease protein
DA819_RS25650	COG1131	(ABC) transporter
DA819_RS25655	COG0515	serine threonine protein kinase
DA819_RS25655	COG3266	domain, Protein
DA819_RS25665	COG0515	serine threonine protein kinase
DA819_RS25725	COG0367	asparagine synthase
DA819_RS25745	COG0469	pyruvate kinase activity
DA819_RS25765	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS25770	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS25805	COG3243	poly(R)-hydroxyalkanoic acid synthase
DA819_RS25845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS25860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DA819_RS25870	COG0559	Belongs to the binding-protein-dependent transport system permease family
DA819_RS25890	COG2022	thiamine diphosphate biosynthetic process
DA819_RS25890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA819_RS25900	COG0300	oxidoreductase activity
DA819_RS26000	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DA819_RS26010	COG2203	Gaf domain
DA819_RS26010	COG3706	GGDEF domain
DA819_RS26010	COG4251	negative regulation of phosphorylation
DA819_RS26010	COG5001	Diguanylate cyclase
DA819_RS26015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA819_RS26040	COG0083	homoserine kinase activity
DA819_RS26065	COG0515	serine threonine protein kinase
DA819_RS26065	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS26110	COG0166	Belongs to the GPI family
DA819_RS26115	COG0280	phosphate acetyltransferase
DA819_RS26115	COG0857	belongs to the CobB CobQ family
DA819_RS26135	COG5001	Diguanylate cyclase
DA819_RS26135	COG1716	ATPase activity
DA819_RS26145	COG1733	regulation of RNA biosynthetic process
DA819_RS26150	COG0574	Belongs to the PEP-utilizing enzyme family
DA819_RS26150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DA819_RS26190	COG4178	(ABC) transporter
DA819_RS26195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DA819_RS26205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA819_RS26220	COG4191	Histidine kinase
DA819_RS26220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS26225	COG1028	Short-chain dehydrogenase reductase Sdr
DA819_RS26290	COG0237	dephospho-CoA kinase activity
DA819_RS26295	COG5398	heme oxygenase
DA819_RS26300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DA819_RS26310	COG3852	Histidine kinase
DA819_RS26325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS26355	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA819_RS26355	COG0022	dehydrogenase e1 component
DA819_RS26360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DA819_RS26365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DA819_RS26380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA819_RS26415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA819_RS26420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DA819_RS26435	COG1573	uracil-dna glycosylase
DA819_RS26460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DA819_RS26470	COG0484	heat shock protein binding
DA819_RS26480	COG0456	acetyltransferase
DA819_RS26490	COG0746	molybdenum cofactor guanylyltransferase activity
DA819_RS26520	COG0443	Heat shock 70 kDa protein
DA819_RS26545	COG1505	serine-type exopeptidase activity
DA819_RS26555	COG0514	ATP-dependent DNA helicase (RecQ)
DA819_RS26565	COG0584	glycerophosphoryl diester phosphodiesterase
DA819_RS26590	COG3842	ATPase activity
DA819_RS26600	COG1372	Participates in initiation and elongation during chromosome replication
DA819_RS26600	COG0719	Fe-S assembly protein
DA819_RS26605	COG0756	dUTP diphosphatase activity
DA819_RS26610	COG2131	deaminase
DA819_RS26615	COG2304	oxidoreductase activity
DA819_RS26640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DA819_RS26645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DA819_RS26650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DA819_RS26660	COG2181	nitrate reductase activity
DA819_RS26675	COG1140	nitrate reductase beta subunit
DA819_RS26680	COG1140	nitrate reductase beta subunit
DA819_RS26685	COG1140	nitrate reductase beta subunit
DA819_RS26690	COG2346	COG2346, Truncated hemoglobins
DA819_RS26715	COG4636	protein conserved in cyanobacteria
DA819_RS26755	COG4636	protein conserved in cyanobacteria
DA819_RS26855	COG0571	ribonuclease III activity
DA819_RS26860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DA819_RS26865	COG1672	PFAM Archaeal ATPase
DA819_RS26885	COG0343	queuine tRNA-ribosyltransferase activity
DA819_RS26895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DA819_RS26910	COG0667	Aldo Keto reductase
DA819_RS26935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DA819_RS26975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DA819_RS26985	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DA819_RS27000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS27015	COG0706	membrane insertase activity
DA819_RS27025	COG0594	ribonuclease P activity
DA819_RS27030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DA819_RS27075	COG1192	Involved in chromosome partitioning
DA819_RS27080	COG0482	sulfurtransferase activity
DA819_RS27090	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DA819_RS27100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA819_RS27120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA819_RS27125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DA819_RS27135	COG0827	DNA restriction-modification system
DA819_RS27150	COG0745	RESPONSE REGULATOR receiver
DA819_RS27170	COG0628	permease
DA819_RS27200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DA819_RS27215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DA819_RS27220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DA819_RS27225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA819_RS27230	COG2048	Heterodisulfide reductase, subunit B
DA819_RS27235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS27250	COG1943	Transposase
DA819_RS27260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DA819_RS27270	COG5001	Diguanylate cyclase
DA819_RS27275	COG0277	FAD linked oxidase domain protein
DA819_RS27280	COG0247	lactate metabolic process
DA819_RS27285	COG0784	Response regulator, receiver
DA819_RS27285	COG2205	protein histidine kinase activity
DA819_RS27285	COG5002	protein histidine kinase activity
DA819_RS27290	COG0432	Pfam Uncharacterised protein family UPF0047
DA819_RS27305	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DA819_RS27310	COG0312	modulator of DNA gyrase
DA819_RS27315	COG0312	modulator of DNA gyrase
DA819_RS27335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS27360	COG0515	serine threonine protein kinase
DA819_RS27360	COG2815	serine threonine protein kinase
DA819_RS27365	COG3852	Histidine kinase
DA819_RS27375	COG1649	PFAM Uncharacterised BCR, COG1649
DA819_RS27380	COG1696	Membrane protein involved in D-alanine export
DA819_RS27385	COG0481	GTPase activity
DA819_RS27395	COG0681	Belongs to the peptidase S26 family
DA819_RS27415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA819_RS27420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DA819_RS27425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DA819_RS27590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA819_RS27590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA819_RS27605	COG0745	RESPONSE REGULATOR receiver
DA819_RS27620	COG0783	Belongs to the Dps family
DA819_RS27640	COG0539	negative regulation of cytoplasmic translation
DA819_RS27650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DA819_RS27655	COG2022	thiamine diphosphate biosynthetic process
DA819_RS27675	COG0745	RESPONSE REGULATOR receiver
DA819_RS27695	COG1193	negative regulation of DNA recombination
DA819_RS27725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DA819_RS27725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DA819_RS27805	COG1222	aaa ATPase
DA819_RS27815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DA819_RS27860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA819_RS27870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA819_RS27880	COG0731	radical SAM domain protein
DA819_RS27925	COG0003	Pfam Anion-transporting ATPase
DA819_RS27950	COG0675	Transposase, IS605 OrfB family
DA819_RS27955	COG1077	Cell shape determining protein MreB Mrl
DA819_RS28000	COG1132	(ABC) transporter
DA819_RS28010	COG0019	diaminopimelate decarboxylase activity
DA819_RS28050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DA819_RS28055	COG0066	3-isopropylmalate dehydratase activity
DA819_RS28060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DA819_RS28090	COG0546	phosphoglycolate phosphatase activity
DA819_RS28095	COG4279	zinc finger
DA819_RS28120	COG1598	PFAM Uncharacterised protein family UPF0150
DA819_RS28280	COG2089	acid synthase
DA819_RS28305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DA819_RS28310	COG1083	cytidylyl-transferase
DA819_RS28325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA819_RS28330	COG1086	Polysaccharide biosynthesis protein
DA819_RS28385	COG2161	toxin-antitoxin pair type II binding
DA819_RS28410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA819_RS28415	COG1086	Polysaccharide biosynthesis protein
DA819_RS28425	COG1086	Polysaccharide biosynthesis protein
DA819_RS28620	COG0463	Glycosyl transferase, family 2
DA819_RS28650	COG0438	transferase activity, transferring glycosyl groups
DA819_RS28660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DA819_RS28690	COG1797	cobyrinic acid a,c-diamide synthase activity
DA819_RS28890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DA819_RS28905	COG0237	dephospho-CoA kinase activity
DA819_RS28905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DA819_RS28910	COG0586	Pfam SNARE associated Golgi protein
DA819_RS28920	COG1366	Belongs to the anti-sigma-factor antagonist family
DA819_RS28940	COG1619	proteins homologs of microcin C7 resistance protein MccF
DA819_RS28970	COG1489	DNA binding
DA819_RS28995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DA819_RS29015	COG0037	tRNA processing
DA819_RS29020	COG0463	Glycosyl transferase, family 2
DA819_RS29035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DA819_RS29045	COG0745	RESPONSE REGULATOR receiver
DA819_RS29050	COG3411	Ferredoxin
DA819_RS29055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DA819_RS29060	COG0459	protein refolding
DA819_RS29070	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DA819_RS29085	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DA819_RS29090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DA819_RS29105	COG0242	peptide deformylase activity
DA819_RS29125	COG0675	Transposase, IS605 OrfB family
DA819_RS29130	COG1836	PFAM Integral membrane protein DUF92
DA819_RS29175	COG0357	Ribosomal RNA small subunit methyltransferase G
DA819_RS29185	COG0616	signal peptide processing
DA819_RS29190	COG0697	spore germination
DA819_RS29205	COG2003	Belongs to the UPF0758 family
DA819_RS29235	COG1741	Belongs to the pirin family
DA819_RS29250	COG1007	ATP synthesis coupled electron transport
DA819_RS29255	COG0500	methyltransferase
DA819_RS29260	COG2226	methyltransferase
DA819_RS29265	COG1280	lysine exporter protein (LysE YggA)
DA819_RS29270	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DA819_RS29275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DA819_RS29290	COG0826	peptidase U32
DA819_RS29300	COG4221	oxidoreductase activity
DA819_RS29305	COG0156	8-amino-7-oxononanoate synthase activity
DA819_RS29315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA819_RS29320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS29330	COG0484	heat shock protein binding
DA819_RS29350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DA819_RS29385	COG0529	Catalyzes the synthesis of activated sulfate
DA819_RS29400	COG0297	glycogen (starch) synthase activity
DA819_RS29420	COG3409	Peptidoglycan-binding domain 1 protein
DA819_RS29420	COG3429	Glucose-6-phosphate dehydrogenase subunit
DA819_RS29425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DA819_RS29430	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DA819_RS29455	COG1271	oxidase subunit
DA819_RS29480	COG0300	oxidoreductase activity
DA819_RS29480	COG3000	fatty acid hydroxylase
DA819_RS29495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DA819_RS29500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DA819_RS29540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DA819_RS29545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA819_RS29555	COG0514	ATP-dependent DNA helicase (RecQ)
DA819_RS29590	COG4251	negative regulation of phosphorylation
DA819_RS29615	COG0668	transmembrane transport
DA819_RS29630	COG2912	Transglutaminase-like superfamily
DA819_RS29635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DA819_RS29650	COG1872	DUF167
DA819_RS29660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA819_RS29665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DA819_RS29670	COG1268	BioY protein
DA819_RS29675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DA819_RS29690	COG0581	inorganic phosphate transmembrane transporter activity
DA819_RS29695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DA819_RS29700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DA819_RS29750	COG1487	ribonuclease activity
DA819_RS29790	COG2361	Protein of unknown function DUF86
DA819_RS29800	COG2361	Protein of unknown function DUF86
DA819_RS29825	COG0784	Response regulator, receiver
DA819_RS29825	COG2198	Histidine kinase
DA819_RS29825	COG5002	protein histidine kinase activity
DA819_RS29830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DA819_RS29840	COG1376	ErfK ybiS ycfS ynhG family protein
DA819_RS29850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DA819_RS29855	COG1472	Belongs to the glycosyl hydrolase 3 family
DA819_RS29870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DA819_RS29900	COG2911	Protein conserved in bacteria
DA819_RS29900	COG3266	domain, Protein
DA819_RS29900	COG1361	Conserved repeat domain
DA819_RS29905	COG0793	Belongs to the peptidase S41A family
DA819_RS29920	COG0745	RESPONSE REGULATOR receiver
DA819_RS29925	COG0730	response to heat
DA819_RS29935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DA819_RS29935	COG3264	Mechanosensitive ion channel
DA819_RS29940	COG1943	Transposase
DA819_RS29970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS29975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DA819_RS29980	COG0017	Asparaginyl-tRNA synthetase
DA819_RS30045	COG0515	serine threonine protein kinase
DA819_RS30045	COG2815	serine threonine protein kinase
DA819_RS30105	COG0105	UTP biosynthetic process
DA819_RS30110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DA819_RS30145	COG3852	Histidine kinase
DA819_RS30170	COG0297	glycogen (starch) synthase activity
DA819_RS30180	COG2198	Histidine kinase
DA819_RS30180	COG2205	protein histidine kinase activity
DA819_RS30180	COG0784	Response regulator, receiver
DA819_RS30185	COG0702	epimerase
DA819_RS30190	COG0330	HflC and HflK could
DA819_RS30225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA819_RS30230	COG1032	radical SAM domain protein
DA819_RS30235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DA819_RS30240	COG1381	Involved in DNA repair and RecF pathway recombination
DA819_RS30250	COG0270	DNA (cytosine-5-)-methyltransferase activity
DA819_RS30275	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DA819_RS30280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DA819_RS30280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DA819_RS30295	COG3063	Type IV pilus biogenesis stability protein PilW
DA819_RS30305	COG0222	ribosome binding
DA819_RS30310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DA819_RS30315	COG0081	regulation of translation
DA819_RS30320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DA819_RS30325	COG0250	Participates in transcription elongation, termination and antitermination
DA819_RS30330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DA819_RS30340	COG0335	large ribosomal subunit rRNA binding
DA819_RS30345	COG0752	glycyl-tRNA synthetase alpha subunit
DA819_RS30370	COG2205	protein histidine kinase activity
DA819_RS30380	COG0494	nUDIX hydrolase
DA819_RS30385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA819_RS30395	COG0601	transmembrane transport
DA819_RS30405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA819_RS30545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DA819_RS30550	COG3932	Exopolysaccharide synthesis, ExoD
DA819_RS30565	COG0284	orotidine-5'-phosphate decarboxylase activity
DA819_RS30565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DA819_RS30575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DA819_RS30580	COG1882	Formate acetyltransferase
DA819_RS30585	COG0537	adenosine 5'-monophosphoramidase activity
DA819_RS30605	COG1695	Transcriptional regulator
DA819_RS30610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DA819_RS30620	COG2119	membrane
DA819_RS30625	COG1640	4-alpha-glucanotransferase
DA819_RS30630	COG1426	Protein conserved in bacteria
DA819_RS30635	COG1187	pseudouridine synthase activity
DA819_RS30645	COG0575	Belongs to the CDS family
DA819_RS30655	COG1982	Orn Lys Arg decarboxylase major
DA819_RS30660	COG0012	GTP binding
DA819_RS30665	COG1950	PFAM Membrane protein of
DA819_RS30680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA819_RS30685	COG0306	phosphate transporter
DA819_RS30740	COG4456	Virulence-associated protein
DA819_RS30780	COG0464	growth
DA819_RS30860	COG2886	Uncharacterised protein family (UPF0175)
DA819_RS30895	COG2886	Uncharacterised protein family (UPF0175)
DA819_RS30935	COG1598	PFAM Uncharacterised protein family UPF0150
DA819_RS30945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS31015	COG2027	D-alanyl-D-alanine carboxypeptidase
DA819_RS31020	COG2045	Belongs to the ComB family
DA819_RS31025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DA819_RS31050	COG0768	penicillin binding
DA819_RS31060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DA819_RS31090	COG0754	glutathionylspermidine amidase activity
DA819_RS31130	COG0598	Magnesium transport protein CorA
DA819_RS31135	COG0515	serine threonine protein kinase
DA819_RS31135	COG3266	domain, Protein
DA819_RS31140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DA819_RS31145	COG0840	transmembrane signaling receptor activity
DA819_RS31155	COG1543	Belongs to the glycosyl hydrolase 57 family
DA819_RS31175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DA819_RS31225	COG0745	RESPONSE REGULATOR receiver
DA819_RS31240	COG0515	serine threonine protein kinase
DA819_RS31240	COG1357	PFAM Pentapeptide repeats (8 copies)
DA819_RS31245	COG1181	Belongs to the D-alanine--D-alanine ligase family
DA819_RS31255	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
DA819_RS31295	COG0085	RNA polymerase activity
DA819_RS31300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DA819_RS31355	COG4680	protein conserved in bacteria
DA819_RS31400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA819_RS31420	COG1111	helicase
DA819_RS31420	COG1205	dead DEAH box helicase
DA819_RS31435	COG5002	protein histidine kinase activity
DA819_RS31440	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DA819_RS31440	COG0662	Cupin 2, conserved barrel domain protein
DA819_RS31455	COG3937	granule-associated protein
DA819_RS31460	COG0489	protein tyrosine kinase activity
DA819_RS31470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DA819_RS31480	COG1404	Belongs to the peptidase S8 family
DA819_RS31480	COG4935	Belongs to the peptidase S8 family
DA819_RS31490	COG0271	Belongs to the BolA IbaG family
DA819_RS31495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DA819_RS31510	COG0745	RESPONSE REGULATOR receiver
DA819_RS31515	COG1012	belongs to the aldehyde dehydrogenase family
DA819_RS31550	COG0643	Histidine kinase
DA819_RS31550	COG0784	Response regulator, receiver
DA819_RS31550	COG2198	Histidine kinase
DA819_RS31555	COG5002	protein histidine kinase activity
DA819_RS31565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DA819_RS31595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA819_RS31600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA819_RS31615	COG1295	ribonuclease BN
DA819_RS31625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DA819_RS31650	COG0277	FAD linked oxidase domain protein
DA819_RS31655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DA819_RS31675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DA819_RS31695	COG3659	wide pore channel activity
DA819_RS31700	COG3659	wide pore channel activity
DA819_RS31705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA819_RS31725	COG2046	Belongs to the sulfate adenylyltransferase family
DA819_RS31740	COG2205	protein histidine kinase activity
DA819_RS31740	COG0784	Response regulator, receiver
DA819_RS31755	COG5001	Diguanylate cyclase
DA819_RS31760	COG5002	protein histidine kinase activity
DA819_RS31795	COG0242	peptide deformylase activity
DA819_RS31800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain