locus-tag	class	description
ADLECEL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADLECEL_RS00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADLECEL_RS00015	COG0594	ribonuclease P activity
ADLECEL_RS00025	COG0706	membrane insertase activity
ADLECEL_RS00030	COG1847	R3H domain protein
ADLECEL_RS00035	COG0357	Ribosomal RNA small subunit methyltransferase G
ADLECEL_RS00040	COG1192	Involved in chromosome partitioning
ADLECEL_RS00045	COG1475	DNA binding
ADLECEL_RS00050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADLECEL_RS00055	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADLECEL_RS00065	COG1199	ATP-dependent helicase activity
ADLECEL_RS00065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADLECEL_RS00090	COG0629	single-stranded DNA binding
ADLECEL_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADLECEL_RS00100	COG0359	binds to the 23S rRNA
ADLECEL_RS00105	COG0305	Participates in initiation and elongation during chromosome replication
ADLECEL_RS00125	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADLECEL_RS00165	COG1053	succinate dehydrogenase
ADLECEL_RS00165	COG3976	FMN-binding domain protein
ADLECEL_RS00170	COG0622	Phosphoesterase
ADLECEL_RS00175	COG3706	GGDEF domain
ADLECEL_RS00185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADLECEL_RS00190	COG0531	amino acid
ADLECEL_RS00205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADLECEL_RS00220	COG1696	Membrane protein involved in D-alanine export
ADLECEL_RS00240	COG1396	sequence-specific DNA binding
ADLECEL_RS00245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_RS00250	COG0778	Nitroreductase
ADLECEL_RS00260	COG1192	Involved in chromosome partitioning
ADLECEL_RS00265	COG1475	DNA binding
ADLECEL_RS00285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADLECEL_RS00415	COG0791	NLP P60 protein
ADLECEL_RS00495	COG1012	belongs to the aldehyde dehydrogenase family
ADLECEL_RS00505	COG0546	phosphoglycolate phosphatase activity
ADLECEL_RS00515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADLECEL_RS00545	COG0864	Transcriptional regulator
ADLECEL_RS00575	COG0443	Heat shock 70 kDa protein
ADLECEL_RS00580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADLECEL_RS00585	COG0484	heat shock protein binding
ADLECEL_RS00590	COG0789	Transcriptional regulator
ADLECEL_RS00595	COG0542	response to heat
ADLECEL_RS00605	COG0393	Putative heavy-metal-binding
ADLECEL_RS00615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADLECEL_RS00620	COG3279	Response regulator of the LytR AlgR family
ADLECEL_RS00625	COG0166	Belongs to the GPI family
ADLECEL_RS00630	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADLECEL_RS00635	COG0298	carbon dioxide binding
ADLECEL_RS00690	COG2197	response regulator
ADLECEL_RS00710	COG1610	YqeY-like protein
ADLECEL_RS00715	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS00720	COG0243	molybdopterin cofactor binding
ADLECEL_RS00730	COG0577	efflux transmembrane transporter activity
ADLECEL_RS00735	COG1136	(ABC) transporter
ADLECEL_RS00745	COG2205	protein histidine kinase activity
ADLECEL_RS00770	COG3428	Bacterial PH domain
ADLECEL_RS00775	COG4535	Mg2 and Co2 transporter CorC
ADLECEL_RS00785	COG0569	domain protein
ADLECEL_RS00805	COG1115	amino acid carrier protein
ADLECEL_RS00810	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADLECEL_RS00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADLECEL_RS00825	COG0765	amino acid transport
ADLECEL_RS00830	COG1126	abc transporter atp-binding protein
ADLECEL_RS00835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADLECEL_RS00850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_RS00860	COG3655	Transcriptional regulator
ADLECEL_RS00955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_RS00970	COG0528	UMP kinase activity
ADLECEL_RS00975	COG0233	cytoplasmic translational termination
ADLECEL_RS00985	COG4589	Belongs to the CDS family
ADLECEL_RS00990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADLECEL_RS01000	COG0750	zinc metalloprotease
ADLECEL_RS01005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADLECEL_RS01010	COG0442	prolyl-tRNA aminoacylation
ADLECEL_RS01025	COG1053	succinate dehydrogenase
ADLECEL_RS01035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADLECEL_RS01045	COG3620	sequence-specific DNA binding
ADLECEL_RS01070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADLECEL_RS01075	COG0542	response to heat
ADLECEL_RS01095	COG1053	succinate dehydrogenase
ADLECEL_RS01095	COG3976	FMN-binding domain protein
ADLECEL_RS01110	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS01115	COG5002	protein histidine kinase activity
ADLECEL_RS01125	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS01135	COG1136	(ABC) transporter
ADLECEL_RS01185	COG0646	methionine synthase
ADLECEL_RS01185	COG1410	methionine synthase
ADLECEL_RS01190	COG5012	cobalamin binding
ADLECEL_RS01210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADLECEL_RS01225	COG3328	transposase activity
ADLECEL_RS01230	COG0402	S-adenosylhomocysteine deaminase activity
ADLECEL_RS01240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADLECEL_RS01245	COG0085	RNA polymerase activity
ADLECEL_RS01250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADLECEL_RS01255	COG0583	DNA-binding transcription factor activity
ADLECEL_RS01315	COG0140	phosphoribosyl-ATP diphosphatase activity
ADLECEL_RS01320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADLECEL_RS01330	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_RS01350	COG2076	Multidrug Resistance protein
ADLECEL_RS01370	COG2326	polyphosphate kinase activity
ADLECEL_RS01375	COG4509	Sortase family
ADLECEL_RS01380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADLECEL_RS01385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADLECEL_RS01390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADLECEL_RS01405	COG0138	bifunctional purine biosynthesis protein purh
ADLECEL_RS01435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADLECEL_RS01440	COG1053	succinate dehydrogenase
ADLECEL_RS01445	COG2197	response regulator
ADLECEL_RS01450	COG2304	oxidoreductase activity
ADLECEL_RS01460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_RS01465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADLECEL_RS01470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADLECEL_RS01475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADLECEL_RS01485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADLECEL_RS01510	COG2357	RelA SpoT domain protein
ADLECEL_RS01520	COG0215	cysteine-tRNA ligase activity
ADLECEL_RS01525	COG1053	succinate dehydrogenase
ADLECEL_RS01525	COG3976	FMN-binding domain protein
ADLECEL_RS01540	COG1131	(ABC) transporter
ADLECEL_RS01560	COG0826	peptidase U32
ADLECEL_RS01575	COG0545	Peptidyl-prolyl cis-trans isomerase
ADLECEL_RS01580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADLECEL_RS01585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADLECEL_RS01590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADLECEL_RS01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADLECEL_RS01600	COG0137	argininosuccinate synthase activity
ADLECEL_RS01610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADLECEL_RS01620	COG0826	peptidase U32
ADLECEL_RS01625	COG1053	succinate dehydrogenase
ADLECEL_RS01635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADLECEL_RS01695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADLECEL_RS01705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADLECEL_RS01710	COG3383	formate dehydrogenase (NAD+) activity
ADLECEL_RS01715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADLECEL_RS01720	COG0651	ATP synthesis coupled electron transport
ADLECEL_RS01725	COG0650	Formate hydrogenlyase subunit 4
ADLECEL_RS01730	COG4237	Hydrogenase 4 membrane
ADLECEL_RS01735	COG0651	ATP synthesis coupled electron transport
ADLECEL_RS01740	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ADLECEL_RS01740	COG3261	NADH dehydrogenase
ADLECEL_RS01745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADLECEL_RS01750	COG3260	NADH ubiquinone oxidoreductase 20
ADLECEL_RS01760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADLECEL_RS01765	COG2116	formate transmembrane transporter activity
ADLECEL_RS01770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ADLECEL_RS01795	COG0586	Pfam SNARE associated Golgi protein
ADLECEL_RS01800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADLECEL_RS01805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADLECEL_RS01810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADLECEL_RS01825	COG1288	antiporter activity
ADLECEL_RS01835	COG0024	Methionine aminopeptidase
ADLECEL_RS01845	COG0697	spore germination
ADLECEL_RS01855	COG0477	Major facilitator Superfamily
ADLECEL_RS01870	COG0484	heat shock protein binding
ADLECEL_RS01900	COG1924	4 iron, 4 sulfur cluster binding
ADLECEL_RS01905	COG2814	Major facilitator Superfamily
ADLECEL_RS01965	COG3550	peptidyl-serine autophosphorylation
ADLECEL_RS01975	COG0326	Molecular chaperone. Has ATPase activity
ADLECEL_RS01995	COG3956	TIGRFAM MazG family protein
ADLECEL_RS02005	COG3976	FMN-binding domain protein
ADLECEL_RS02005	COG1053	succinate dehydrogenase
ADLECEL_RS02010	COG1228	amidohydrolase
ADLECEL_RS02015	COG2235	arginine
ADLECEL_RS02020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_RS02030	COG1834	amidinotransferase
ADLECEL_RS02045	COG0477	Major facilitator Superfamily
ADLECEL_RS02055	COG1834	amidinotransferase
ADLECEL_RS02065	COG1053	succinate dehydrogenase
ADLECEL_RS02065	COG3976	FMN-binding domain protein
ADLECEL_RS02070	COG0583	DNA-binding transcription factor activity
ADLECEL_RS02080	COG0436	Aminotransferase
ADLECEL_RS02105	COG2414	aldehyde ferredoxin oxidoreductase
ADLECEL_RS02110	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS02130	COG1876	peptidase activity
ADLECEL_RS02160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_RS02180	COG0482	sulfurtransferase activity
ADLECEL_RS02185	COG1053	succinate dehydrogenase
ADLECEL_RS02190	COG2197	response regulator
ADLECEL_RS02200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADLECEL_RS02205	COG2205	protein histidine kinase activity
ADLECEL_RS02205	COG0784	Response regulator, receiver
ADLECEL_RS02240	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS02245	COG0542	response to heat
ADLECEL_RS02265	COG2197	response regulator
ADLECEL_RS02365	COG0560	Phosphoserine phosphatase
ADLECEL_RS02390	COG2843	Capsule synthesis protein
ADLECEL_RS02395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADLECEL_RS02405	COG3321	synthase
ADLECEL_RS02405	COG0604	alcohol dehydrogenase
ADLECEL_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_RS02420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADLECEL_RS02425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADLECEL_RS02425	COG0825	malonyl-CoA metabolic process
ADLECEL_RS02430	COG1748	Saccharopine dehydrogenase
ADLECEL_RS02450	COG1131	(ABC) transporter
ADLECEL_RS02470	COG2815	serine threonine protein kinase
ADLECEL_RS02470	COG0515	serine threonine protein kinase
ADLECEL_RS02490	COG1968	undecaprenyl-diphosphatase activity
ADLECEL_RS02500	COG1725	Transcriptional regulator
ADLECEL_RS02515	COG3550	peptidyl-serine autophosphorylation
ADLECEL_RS02535	COG0243	molybdopterin cofactor binding
ADLECEL_RS02540	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS02570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADLECEL_RS02590	COG3845	ABC transporter
ADLECEL_RS02595	COG1122	ATPase activity
ADLECEL_RS02600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_RS02610	COG0657	acetylesterase activity
ADLECEL_RS02615	COG3973	AAA domain
ADLECEL_RS02640	COG0789	Transcriptional regulator
ADLECEL_RS02675	COG0824	Thioesterase
ADLECEL_RS02680	COG3254	rhamnose metabolic process
ADLECEL_RS02690	COG2848	UPF0210 protein
ADLECEL_RS02700	COG3550	peptidyl-serine autophosphorylation
ADLECEL_RS02705	COG0288	reversible hydration of carbon dioxide
ADLECEL_RS02720	COG1725	Transcriptional regulator
ADLECEL_RS02725	COG0243	molybdopterin cofactor binding
ADLECEL_RS02730	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS02750	COG1316	TRANSCRIPTIONal
ADLECEL_RS02795	COG0822	iron-sulfur transferase activity
ADLECEL_RS02805	COG1959	2 iron, 2 sulfur cluster binding
ADLECEL_RS02810	COG2205	protein histidine kinase activity
ADLECEL_RS02810	COG0784	Response regulator, receiver
ADLECEL_RS02815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_RS02815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_RS02820	COG0084	hydrolase, TatD family'
ADLECEL_RS02830	COG3550	peptidyl-serine autophosphorylation
ADLECEL_RS02845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADLECEL_RS02855	COG1247	-acetyltransferase
ADLECEL_RS02865	COG0538	isocitrate dehydrogenase activity
ADLECEL_RS02875	COG2197	response regulator
ADLECEL_RS02905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADLECEL_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_RS02915	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS02920	COG0243	molybdopterin cofactor binding
ADLECEL_RS02935	COG0348	domain, Protein
ADLECEL_RS02950	COG1138	Cytochrome C-type biogenesis protein
ADLECEL_RS02955	COG4555	ABC transporter
ADLECEL_RS02980	COG1733	regulation of RNA biosynthetic process
ADLECEL_RS03000	COG3976	FMN-binding domain protein
ADLECEL_RS03000	COG1053	succinate dehydrogenase
ADLECEL_RS03020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADLECEL_RS03040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADLECEL_RS03045	COG2003	Belongs to the UPF0758 family
ADLECEL_RS03055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ADLECEL_RS03060	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_RS03085	COG3328	transposase activity
ADLECEL_RS03105	COG3853	Toxic anion resistance protein (TelA)
ADLECEL_RS03110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADLECEL_RS03125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADLECEL_RS03135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADLECEL_RS03140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADLECEL_RS03145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADLECEL_RS03150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADLECEL_RS03155	COG0006	proline dipeptidase activity
ADLECEL_RS03165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADLECEL_RS03180	COG1053	succinate dehydrogenase
ADLECEL_RS03185	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADLECEL_RS03195	COG0511	ligase activity, forming carbon-carbon bonds
ADLECEL_RS03195	COG5016	pyruvate
ADLECEL_RS03200	COG0439	Biotin carboxylase
ADLECEL_RS03210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADLECEL_RS03220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADLECEL_RS03230	COG0004	ammonium transporteR
ADLECEL_RS03235	COG0347	Belongs to the P(II) protein family
ADLECEL_RS03260	COG0539	negative regulation of cytoplasmic translation
ADLECEL_RS03265	COG0237	dephospho-CoA kinase activity
ADLECEL_RS03270	COG2197	response regulator
ADLECEL_RS03275	COG1053	succinate dehydrogenase
ADLECEL_RS03295	COG0556	nucleotide-excision repair
ADLECEL_RS03305	COG0497	DNA recombination
ADLECEL_RS03325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADLECEL_RS03330	COG0072	phenylalanine-tRNA ligase activity
ADLECEL_RS03335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADLECEL_RS03340	COG0736	holo-[acyl-carrier-protein] synthase activity
ADLECEL_RS03365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADLECEL_RS03375	COG3942	CHAP domain
ADLECEL_RS03375	COG1705	Flagellar rod assembly protein muramidase FlgJ
ADLECEL_RS03380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADLECEL_RS03400	COG0653	protein targeting
ADLECEL_RS03405	COG3657	addiction module killer protein
ADLECEL_RS03415	COG1682	transport, permease protein
ADLECEL_RS03420	COG1134	teichoic acid transport
ADLECEL_RS03425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADLECEL_RS03490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADLECEL_RS03505	COG1216	Glycosyl transferase, family 2
ADLECEL_RS03565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ADLECEL_RS03570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADLECEL_RS03580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADLECEL_RS03610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADLECEL_RS03620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADLECEL_RS03620	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_RS03635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADLECEL_RS03640	COG1696	Membrane protein involved in D-alanine export
ADLECEL_RS03670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADLECEL_RS03685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADLECEL_RS03690	COG0463	Glycosyl transferase, family 2
ADLECEL_RS03705	COG0151	Belongs to the GarS family
ADLECEL_RS03710	COG1088	dTDP-glucose 4,6-dehydratase activity
ADLECEL_RS03715	COG4193	domain, Protein
ADLECEL_RS03720	COG1376	ErfK ybiS ycfS ynhG family protein
ADLECEL_RS03730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADLECEL_RS03750	COG1773	rubredoxin
ADLECEL_RS03750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADLECEL_RS03760	COG0343	queuine tRNA-ribosyltransferase activity
ADLECEL_RS03765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADLECEL_RS03785	COG2197	response regulator
ADLECEL_RS03790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADLECEL_RS03790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADLECEL_RS03800	COG2197	response regulator
ADLECEL_RS03815	COG0535	radical SAM domain protein
ADLECEL_RS03825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_RS03830	COG1120	ATPase activity
ADLECEL_RS03840	COG1122	ATPase activity
ADLECEL_RS03845	COG1122	ATPase activity
ADLECEL_RS03850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_RS03860	COG1115	amino acid carrier protein
ADLECEL_RS03865	COG1115	amino acid carrier protein
ADLECEL_RS03870	COG2081	HI0933 family
ADLECEL_RS03875	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ADLECEL_RS03880	COG2267	carboxylic ester hydrolase activity
ADLECEL_RS03885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADLECEL_RS03895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADLECEL_RS03905	COG2131	deaminase
ADLECEL_RS03920	COG0356	it plays a direct role in the translocation of protons across the membrane
ADLECEL_RS03930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADLECEL_RS03935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADLECEL_RS03940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADLECEL_RS03945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADLECEL_RS03950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADLECEL_RS03985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADLECEL_RS04005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADLECEL_RS04020	COG0101	tRNA pseudouridine synthase activity
ADLECEL_RS04025	COG4656	Part of a membrane complex involved in electron transport
ADLECEL_RS04030	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_RS04035	COG0012	GTP binding
ADLECEL_RS04055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADLECEL_RS04060	COG0154	amidase activity
ADLECEL_RS04065	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADLECEL_RS04075	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADLECEL_RS04085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADLECEL_RS04095	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_RS04100	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_RS04120	COG1053	succinate dehydrogenase
ADLECEL_RS04125	COG2197	response regulator
ADLECEL_RS04135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADLECEL_RS04165	COG2235	arginine
ADLECEL_RS04170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_RS04175	COG1288	antiporter activity
ADLECEL_RS04180	COG0018	arginyl-trna synthetase
ADLECEL_RS04195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADLECEL_RS04195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADLECEL_RS04220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADLECEL_RS04240	COG0025	NhaP-type Na H and K H
ADLECEL_RS04245	COG0180	Tryptophanyl-tRNA synthetase
ADLECEL_RS04260	COG0494	nUDIX hydrolase
ADLECEL_RS04265	COG0488	(ABC) transporter
ADLECEL_RS04275	COG0025	NhaP-type Na H and K H
ADLECEL_RS04290	COG1994	Peptidase M50
ADLECEL_RS04305	COG1187	pseudouridine synthase activity
ADLECEL_RS04310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADLECEL_RS04315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADLECEL_RS04330	COG0784	Response regulator, receiver
ADLECEL_RS04330	COG2205	protein histidine kinase activity
ADLECEL_RS04365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADLECEL_RS04370	COG0204	Acyl-transferase
ADLECEL_RS04375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADLECEL_RS04385	COG1160	GTP binding
ADLECEL_RS04390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADLECEL_RS04395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADLECEL_RS04400	COG2205	protein histidine kinase activity
ADLECEL_RS04400	COG0784	Response regulator, receiver
ADLECEL_RS04400	COG5002	protein histidine kinase activity
ADLECEL_RS04410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADLECEL_RS04415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADLECEL_RS04420	COG1104	cysteine desulfurase activity
ADLECEL_RS04440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADLECEL_RS04445	COG1302	Protein conserved in bacteria
ADLECEL_RS04450	COG1461	Dihydroxyacetone kinase
ADLECEL_RS04455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADLECEL_RS04460	COG0742	ribosomal rna small subunit methyltransferase
ADLECEL_RS04475	COG0038	chloride channel
ADLECEL_RS04480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADLECEL_RS04485	COG0416	fatty acid biosynthetic process
ADLECEL_RS04490	COG0571	ribonuclease III activity
ADLECEL_RS04495	COG1196	nuclear chromosome segregation
ADLECEL_RS04510	COG0243	molybdopterin cofactor binding
ADLECEL_RS04525	COG0243	molybdopterin cofactor binding
ADLECEL_RS04530	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS04555	COG0243	molybdopterin cofactor binding
ADLECEL_RS04570	COG2226	methyltransferase
ADLECEL_RS04580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADLECEL_RS04585	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_RS04605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADLECEL_RS04625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADLECEL_RS04635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADLECEL_RS04645	COG0513	Belongs to the DEAD box helicase family
ADLECEL_RS04650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADLECEL_RS04670	COG1597	lipid kinase activity
ADLECEL_RS04680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADLECEL_RS04685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADLECEL_RS04695	COG0105	UTP biosynthetic process
ADLECEL_RS04720	COG1077	Cell shape determining protein MreB Mrl
ADLECEL_RS04725	COG1792	Involved in formation and maintenance of cell shape
ADLECEL_RS04740	COG0772	Belongs to the SEDS family
ADLECEL_RS04760	COG0537	adenosine 5'-monophosphoramidase activity
ADLECEL_RS04785	COG1151	hydroxylamine reductase activity
ADLECEL_RS04790	COG2816	NAD+ diphosphatase activity
ADLECEL_RS04805	COG0335	large ribosomal subunit rRNA binding
ADLECEL_RS04815	COG0792	nuclease activity
ADLECEL_RS04820	COG0606	chelatase, subunit chli
ADLECEL_RS04825	COG0758	DNA mediated transformation
ADLECEL_RS04830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ADLECEL_RS04845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADLECEL_RS04855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADLECEL_RS04920	COG1074	ATP-dependent DNA helicase activity
ADLECEL_RS04940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADLECEL_RS04950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADLECEL_RS04960	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_RS04980	COG1960	acyl-CoA dehydrogenase activity
ADLECEL_RS04990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADLECEL_RS04995	COG2086	electron transfer activity
ADLECEL_RS05000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADLECEL_RS05005	COG2181	nitrate reductase activity
ADLECEL_RS05005	COG0247	lactate metabolic process
ADLECEL_RS05025	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_RS05030	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_RS05055	COG0243	molybdopterin cofactor binding
ADLECEL_RS05060	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS05080	COG0243	molybdopterin cofactor binding
ADLECEL_RS05100	COG1846	Transcriptional regulator
ADLECEL_RS05105	COG0243	molybdopterin cofactor binding
ADLECEL_RS05110	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS05135	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS05160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_RS05180	COG4134	Bacterial extracellular solute-binding protein
ADLECEL_RS05185	COG1177	transmembrane transport
ADLECEL_RS05195	COG3842	ATPase activity
ADLECEL_RS05220	COG1960	acyl-CoA dehydrogenase activity
ADLECEL_RS05230	COG0583	DNA-binding transcription factor activity
ADLECEL_RS05235	COG0779	Required for maturation of 30S ribosomal subunits
ADLECEL_RS05240	COG0195	Participates in both transcription termination and antitermination
ADLECEL_RS05250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADLECEL_RS05250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADLECEL_RS05255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADLECEL_RS05260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ADLECEL_RS05265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADLECEL_RS05270	COG0196	riboflavin kinase activity
ADLECEL_RS05275	COG1368	sulfuric ester hydrolase activity
ADLECEL_RS05285	COG1660	Displays ATPase and GTPase activities
ADLECEL_RS05290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ADLECEL_RS05295	COG1481	regulation of sporulation
ADLECEL_RS05305	COG0126	phosphoglycerate kinase activity
ADLECEL_RS05310	COG0149	triose-phosphate isomerase activity
ADLECEL_RS05315	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADLECEL_RS05320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADLECEL_RS05340	COG0861	Integral membrane protein TerC family
ADLECEL_RS05375	COG1597	lipid kinase activity
ADLECEL_RS05380	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ADLECEL_RS05385	COG2738	Putative neutral zinc metallopeptidase
ADLECEL_RS05390	COG1570	exodeoxyribonuclease VII activity
ADLECEL_RS05395	COG1722	exodeoxyribonuclease VII activity
ADLECEL_RS05400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADLECEL_RS05405	COG1053	succinate dehydrogenase
ADLECEL_RS05405	COG3976	FMN-binding domain protein
ADLECEL_RS05415	COG0280	phosphate acetyltransferase
ADLECEL_RS05425	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_RS05435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADLECEL_RS05440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADLECEL_RS05450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADLECEL_RS05455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADLECEL_RS05460	COG0564	pseudouridine synthase activity
ADLECEL_RS05465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADLECEL_RS05490	COG3976	FMN-binding domain protein
ADLECEL_RS05490	COG1053	succinate dehydrogenase
ADLECEL_RS05495	COG2197	response regulator
ADLECEL_RS05500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADLECEL_RS05505	COG1053	succinate dehydrogenase
ADLECEL_RS05505	COG3976	FMN-binding domain protein
ADLECEL_RS05530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADLECEL_RS05530	COG2111	Na H antiporter
ADLECEL_RS05535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADLECEL_RS05540	COG3260	NADH ubiquinone oxidoreductase 20
ADLECEL_RS05555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADLECEL_RS05565	COG2720	vancomycin resistance protein
ADLECEL_RS05580	COG1686	Belongs to the peptidase S11 family
ADLECEL_RS05605	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADLECEL_RS05610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADLECEL_RS05630	COG0756	dUTP diphosphatase activity
ADLECEL_RS05635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADLECEL_RS05640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADLECEL_RS05645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADLECEL_RS05655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADLECEL_RS05660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_RS05665	COG2359	stage V sporulation protein S
ADLECEL_RS05675	COG1418	mRNA catabolic process
ADLECEL_RS05690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADLECEL_RS05695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_RS05700	COG1666	GTP binding
ADLECEL_RS05715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADLECEL_RS05720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADLECEL_RS05725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADLECEL_RS05730	COG1185	polyribonucleotide nucleotidyltransferase activity
ADLECEL_RS05735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADLECEL_RS05755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADLECEL_RS05770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_RS05780	COG0484	heat shock protein binding
ADLECEL_RS05785	COG1420	regulation of RNA biosynthetic process
ADLECEL_RS05790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADLECEL_RS05795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADLECEL_RS05810	COG0481	GTPase activity
ADLECEL_RS05815	COG0268	Binds directly to 16S ribosomal RNA
ADLECEL_RS05830	COG0658	competence protein
ADLECEL_RS05830	COG2333	competence protein COMEC
ADLECEL_RS05835	COG1596	polysaccharide export
ADLECEL_RS05835	COG1555	photosystem II stabilization
ADLECEL_RS05840	COG0301	tRNA thio-modification
ADLECEL_RS05850	COG0194	GDP metabolic process
ADLECEL_RS05860	COG0284	orotidine-5'-phosphate decarboxylase activity
ADLECEL_RS05865	COG0167	dihydroorotate dehydrogenase activity
ADLECEL_RS05870	COG0543	2 iron, 2 sulfur cluster binding
ADLECEL_RS05875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADLECEL_RS05880	COG0505	Belongs to the CarA family
ADLECEL_RS05915	COG1120	ATPase activity
ADLECEL_RS05920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_RS05925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_RS05930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADLECEL_RS05935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADLECEL_RS05940	COG0540	Belongs to the ATCase OTCase family
ADLECEL_RS05945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADLECEL_RS05950	COG1592	Rubrerythrin
ADLECEL_RS05955	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADLECEL_RS05965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADLECEL_RS05985	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_RS05985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADLECEL_RS05990	COG1144	Oxidoreductase
ADLECEL_RS06000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADLECEL_RS06010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADLECEL_RS06010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADLECEL_RS06015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADLECEL_RS06020	COG0242	peptide deformylase activity
ADLECEL_RS06025	COG0358	DNA primase activity
ADLECEL_RS06030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_RS06035	COG0328	RNA-DNA hybrid ribonuclease activity
ADLECEL_RS06045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_RS06050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADLECEL_RS06055	COG0440	acetolactate synthase activity
ADLECEL_RS06060	COG0028	Belongs to the TPP enzyme family
ADLECEL_RS06065	COG0129	dihydroxy-acid dehydratase activity
ADLECEL_RS06080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADLECEL_RS06085	COG2890	protein-(glutamine-N5) methyltransferase activity
ADLECEL_RS06090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADLECEL_RS06110	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS06115	COG0243	molybdopterin cofactor binding
ADLECEL_RS06125	COG0475	glutathione-regulated potassium exporter activity
ADLECEL_RS06125	COG0569	domain protein
ADLECEL_RS06135	COG0492	ferredoxin-NADP+ reductase activity
ADLECEL_RS06140	COG4145	pantothenate transmembrane transporter activity
ADLECEL_RS06150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADLECEL_RS06165	COG0525	valine-tRNA ligase activity
ADLECEL_RS06170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADLECEL_RS06175	COG0740	serine-type endopeptidase activity
ADLECEL_RS06180	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADLECEL_RS06275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ADLECEL_RS06290	COG0116	Belongs to the methyltransferase superfamily
ADLECEL_RS06290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADLECEL_RS06295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADLECEL_RS06295	COG0116	Belongs to the methyltransferase superfamily
ADLECEL_RS06300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADLECEL_RS06305	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS06315	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS06320	COG0243	molybdopterin cofactor binding
ADLECEL_RS06335	COG1053	succinate dehydrogenase
ADLECEL_RS06340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADLECEL_RS06360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADLECEL_RS06375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADLECEL_RS06405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADLECEL_RS06440	COG1476	TRANSCRIPTIONal
ADLECEL_RS06490	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADLECEL_RS06495	COG1605	Chorismate mutase
ADLECEL_RS06495	COG0077	Prephenate dehydratase
ADLECEL_RS06510	COG1194	a g-specific adenine glycosylase
ADLECEL_RS06525	COG1132	(ABC) transporter
ADLECEL_RS06540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADLECEL_RS06560	COG1192	Involved in chromosome partitioning
ADLECEL_RS06565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADLECEL_RS06575	COG0574	Belongs to the PEP-utilizing enzyme family
ADLECEL_RS06575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADLECEL_RS06585	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADLECEL_RS06590	COG0751	glycine-tRNA ligase activity
ADLECEL_RS06600	COG0681	Belongs to the peptidase S26 family
ADLECEL_RS06605	COG0336	Belongs to the RNA methyltransferase TrmD family
ADLECEL_RS06610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADLECEL_RS06615	COG1837	Belongs to the UPF0109 family
ADLECEL_RS06635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADLECEL_RS06640	COG0601	transmembrane transport
ADLECEL_RS06660	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_RS06670	COG0557	exoribonuclease II activity
ADLECEL_RS06680	COG2177	Part of the ABC transporter FtsEX involved in
ADLECEL_RS06685	COG2884	Cell division ATP-binding protein ftsE
ADLECEL_RS06690	COG3958	Transketolase
ADLECEL_RS06700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADLECEL_RS06705	COG0653	protein targeting
ADLECEL_RS06720	COG1294	oxidase, subunit
ADLECEL_RS06725	COG1271	oxidase subunit
ADLECEL_RS06750	COG0799	negative regulation of ribosome biogenesis
ADLECEL_RS06755	COG1713	HD superfamily hydrolase involved in NAD metabolism
ADLECEL_RS06755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADLECEL_RS06760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADLECEL_RS06765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADLECEL_RS06770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADLECEL_RS06775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADLECEL_RS06780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADLECEL_RS06785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADLECEL_RS06790	COG1288	antiporter activity
ADLECEL_RS06795	COG2235	arginine
ADLECEL_RS06800	COG2197	response regulator
ADLECEL_RS06805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADLECEL_RS06805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADLECEL_RS06810	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS06815	COG0174	glutamine synthetase
ADLECEL_RS06825	COG2033	superoxide reductase activity
ADLECEL_RS06830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADLECEL_RS06845	COG0316	Belongs to the HesB IscA family
ADLECEL_RS06845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADLECEL_RS06875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_RS06875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_RS06890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADLECEL_RS06895	COG0583	DNA-binding transcription factor activity
ADLECEL_RS06905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADLECEL_RS06915	COG0107	imidazoleglycerol-phosphate synthase activity
ADLECEL_RS06920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADLECEL_RS06925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADLECEL_RS06930	COG0131	Imidazoleglycerol-phosphate dehydratase
ADLECEL_RS06935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADLECEL_RS06940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADLECEL_RS06945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADLECEL_RS06950	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ADLECEL_RS06955	COG1691	(AIR) carboxylase
ADLECEL_RS06960	COG0789	Transcriptional regulator
ADLECEL_RS06970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADLECEL_RS06995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADLECEL_RS07000	COG1363	Peptidase, m42
ADLECEL_RS07025	COG3409	Peptidoglycan-binding domain 1 protein
ADLECEL_RS07365	COG1307	EDD domain protein, DegV family
ADLECEL_RS07380	COG1307	EDD domain protein, DegV family
ADLECEL_RS07385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ADLECEL_RS07400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADLECEL_RS07405	COG0281	malic enzyme
ADLECEL_RS07415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADLECEL_RS07415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADLECEL_RS07420	COG0551	DNA topoisomerase type I activity
ADLECEL_RS07420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADLECEL_RS07450	COG0765	amino acid transport
ADLECEL_RS07455	COG0765	amino acid transport
ADLECEL_RS07470	COG3872	metal-dependent enzyme
ADLECEL_RS07475	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ADLECEL_RS07480	COG2226	methyltransferase
ADLECEL_RS07485	COG1278	Cold shock
ADLECEL_RS07495	COG2255	four-way junction helicase activity
ADLECEL_RS07510	COG1192	Involved in chromosome partitioning
ADLECEL_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_RS07530	COG0217	transcriptional regulatory protein
ADLECEL_RS07535	COG2909	trisaccharide binding
ADLECEL_RS07540	COG1053	succinate dehydrogenase
ADLECEL_RS07550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_RS07560	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_RS07560	COG3976	FMN-binding domain protein
ADLECEL_RS07570	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS07575	COG0243	molybdopterin cofactor binding
ADLECEL_RS07585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADLECEL_RS07590	COG4149	molybdate abc transporter
ADLECEL_RS07620	COG0617	tRNA 3'-terminal CCA addition
ADLECEL_RS07655	COG1053	succinate dehydrogenase
ADLECEL_RS07660	COG0351	phosphomethylpyrimidine kinase
ADLECEL_RS07665	COG1335	isochorismatase
ADLECEL_RS07670	COG0352	thiamine-phosphate diphosphorylase activity
ADLECEL_RS07675	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADLECEL_RS07695	COG0762	integral membrane protein
ADLECEL_RS07700	COG1799	cell septum assembly
ADLECEL_RS07715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADLECEL_RS07720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADLECEL_RS07725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADLECEL_RS07730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADLECEL_RS07735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADLECEL_RS07740	COG0772	Belongs to the SEDS family
ADLECEL_RS07745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADLECEL_RS07765	COG0768	penicillin binding
ADLECEL_RS07775	COG0275	rRNA processing
ADLECEL_RS07780	COG2001	Belongs to the MraZ family
ADLECEL_RS07785	COG4974	Belongs to the 'phage' integrase family
ADLECEL_RS07790	COG0252	asparaginase activity
ADLECEL_RS07795	COG2860	membrane
ADLECEL_RS07800	COG4868	Belongs to the UPF0371 family
ADLECEL_RS07810	COG0504	CTP synthase activity
ADLECEL_RS07820	COG1396	sequence-specific DNA binding
ADLECEL_RS07820	COG1917	Cupin 2, conserved barrel domain protein
ADLECEL_RS07830	COG0024	Methionine aminopeptidase
ADLECEL_RS07840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADLECEL_RS07845	COG0081	regulation of translation
ADLECEL_RS07850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADLECEL_RS07855	COG0250	Participates in transcription elongation, termination and antitermination
ADLECEL_RS07860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADLECEL_RS07870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADLECEL_RS07900	COG0426	domain, Protein
ADLECEL_RS07905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADLECEL_RS07910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_RS07920	COG1794	racemase activity, acting on amino acids and derivatives
ADLECEL_RS07935	COG1725	Transcriptional regulator
ADLECEL_RS07950	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS07955	COG0243	molybdopterin cofactor binding
ADLECEL_RS07960	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_RS07960	COG3976	FMN-binding domain protein
ADLECEL_RS07980	COG0747	negative chemotaxis
ADLECEL_RS07990	COG0563	adenylate kinase activity
ADLECEL_RS08000	COG0200	Binds to the 23S rRNA
ADLECEL_RS08005	COG1841	ribosomal large subunit assembly
ADLECEL_RS08010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADLECEL_RS08015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADLECEL_RS08020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADLECEL_RS08025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADLECEL_RS08030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADLECEL_RS08035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADLECEL_RS08040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADLECEL_RS08045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADLECEL_RS08050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADLECEL_RS08060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADLECEL_RS08065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADLECEL_RS08075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADLECEL_RS08080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADLECEL_RS08105	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADLECEL_RS08120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADLECEL_RS08125	COG1053	succinate dehydrogenase
ADLECEL_RS08140	COG1136	(ABC) transporter
ADLECEL_RS08165	COG2197	response regulator
ADLECEL_RS08180	COG0089	rRNA binding
ADLECEL_RS08185	COG0088	Forms part of the polypeptide exit tunnel
ADLECEL_RS08190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADLECEL_RS08195	COG0051	transcription antitermination factor activity, RNA binding
ADLECEL_RS08200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADLECEL_RS08205	COG0049	tRNA binding
ADLECEL_RS08210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADLECEL_RS08215	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADLECEL_RS08220	COG1227	inorganic diphosphatase activity
ADLECEL_RS08225	COG1760	l-serine dehydratase
ADLECEL_RS08235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADLECEL_RS08260	COG0494	nUDIX hydrolase
ADLECEL_RS08270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADLECEL_RS08285	COG2860	membrane
ADLECEL_RS08295	COG0306	phosphate transporter
ADLECEL_RS08300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADLECEL_RS08305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADLECEL_RS08310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADLECEL_RS08310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ADLECEL_RS08315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADLECEL_RS08320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADLECEL_RS08325	COG0602	queuosine metabolic process
ADLECEL_RS08330	COG0720	synthase
ADLECEL_RS08340	COG0583	DNA-binding transcription factor activity
ADLECEL_RS08355	COG2197	response regulator
ADLECEL_RS08360	COG1739	Uncharacterized protein family UPF0029
ADLECEL_RS08365	COG0488	(ABC) transporter
ADLECEL_RS08370	COG2814	Major facilitator Superfamily
ADLECEL_RS08375	COG0193	aminoacyl-tRNA hydrolase activity
ADLECEL_RS08380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADLECEL_RS08385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADLECEL_RS08395	COG2217	Heavy metal translocating P-type atpase
ADLECEL_RS08400	COG1937	Protein conserved in bacteria
ADLECEL_RS08415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADLECEL_RS08425	COG0598	Magnesium transport protein CorA
ADLECEL_RS08430	COG1573	uracil-dna glycosylase
ADLECEL_RS08435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADLECEL_RS08440	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADLECEL_RS08445	COG0303	'Molybdopterin
ADLECEL_RS08450	COG1132	(ABC) transporter
ADLECEL_RS08455	COG2197	response regulator
ADLECEL_RS08460	COG1053	succinate dehydrogenase
ADLECEL_RS08460	COG3976	FMN-binding domain protein
ADLECEL_RS08465	COG2814	Major facilitator Superfamily
ADLECEL_RS08475	COG4716	Myosin-crossreactive antigen
ADLECEL_RS08485	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_RS08495	COG0203	ribosomal protein L17
ADLECEL_RS08500	COG0202	RNA polymerase activity
ADLECEL_RS08505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADLECEL_RS08510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADLECEL_RS08525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADLECEL_RS08530	COG0189	ligase activity
ADLECEL_RS08530	COG2918	glutathione biosynthetic process
ADLECEL_RS08545	COG2814	Major facilitator Superfamily
ADLECEL_RS08575	COG0459	protein refolding
ADLECEL_RS08580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADLECEL_RS08585	COG2197	response regulator
ADLECEL_RS08590	COG4585	Histidine kinase
ADLECEL_RS08595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADLECEL_RS08595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADLECEL_RS08605	COG0805	protein transport
ADLECEL_RS08610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_RS08620	COG0402	S-adenosylhomocysteine deaminase activity
ADLECEL_RS08625	COG2226	methyltransferase
ADLECEL_RS08640	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
ADLECEL_RS08660	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS08665	COG0243	molybdopterin cofactor binding
ADLECEL_RS08670	COG0330	HflC and HflK could
ADLECEL_RS08685	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS08690	COG2205	protein histidine kinase activity
ADLECEL_RS08705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ADLECEL_RS08720	COG0802	atpase or kinase
ADLECEL_RS08725	COG2116	formate transmembrane transporter activity
ADLECEL_RS08730	COG3976	FMN-binding domain protein
ADLECEL_RS08730	COG1053	succinate dehydrogenase
ADLECEL_RS08735	COG2909	trisaccharide binding
ADLECEL_RS08740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADLECEL_RS08745	COG3404	Formiminotransferase-cyclodeaminase
ADLECEL_RS08750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ADLECEL_RS08755	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADLECEL_RS08760	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS08775	COG1268	BioY protein
ADLECEL_RS08790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADLECEL_RS08795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADLECEL_RS08800	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADLECEL_RS08805	COG0424	maF-like protein
ADLECEL_RS08815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADLECEL_RS08820	COG1950	PFAM Membrane protein of
ADLECEL_RS08825	COG0577	efflux transmembrane transporter activity
ADLECEL_RS08825	COG1136	(ABC) transporter
ADLECEL_RS08830	COG1528	Iron-storage protein
ADLECEL_RS08835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADLECEL_RS08840	COG1272	protein, Hemolysin III
ADLECEL_RS08845	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADLECEL_RS08880	COG0656	L-ascorbic acid biosynthetic process
ADLECEL_RS08885	COG2078	PFAM AMMECR1 domain protein
ADLECEL_RS08885	COG3885	ferrous iron binding
ADLECEL_RS08890	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ADLECEL_RS08895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADLECEL_RS08900	COG3250	beta-galactosidase activity
ADLECEL_RS08925	COG1053	succinate dehydrogenase
ADLECEL_RS08965	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS08970	COG0243	molybdopterin cofactor binding
ADLECEL_RS08975	COG0583	DNA-binding transcription factor activity
ADLECEL_RS08980	COG0656	L-ascorbic acid biosynthetic process
ADLECEL_RS08990	COG1490	D-aminoacyl-tRNA deacylase activity
ADLECEL_RS08995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADLECEL_RS09020	COG1373	ATPase (AAA superfamily
ADLECEL_RS09030	COG0613	PHP domain protein
ADLECEL_RS09035	COG4778	phosphonate C-P lyase system protein PhnL
ADLECEL_RS09040	COG3454	Phosphonate metabolism
ADLECEL_RS09045	COG4107	phosphonate C-P lyase system protein PhnK
ADLECEL_RS09050	COG3627	carbon phosphorus lyase activity
ADLECEL_RS09070	COG3639	organic phosphonate transmembrane transporter activity
ADLECEL_RS09075	COG3639	organic phosphonate transmembrane transporter activity
ADLECEL_RS09080	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADLECEL_RS09095	COG1115	amino acid carrier protein
ADLECEL_RS09100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADLECEL_RS09110	COG1132	(ABC) transporter
ADLECEL_RS09115	COG3973	AAA domain
ADLECEL_RS09130	COG1234	tRNA 3'-trailer cleavage
ADLECEL_RS09140	COG2205	protein histidine kinase activity
ADLECEL_RS09140	COG0784	Response regulator, receiver
ADLECEL_RS09180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADLECEL_RS09180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADLECEL_RS09200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADLECEL_RS09230	COG1053	succinate dehydrogenase
ADLECEL_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_RS09250	COG3976	FMN-binding domain protein
ADLECEL_RS09250	COG1053	succinate dehydrogenase
ADLECEL_RS09255	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADLECEL_RS09270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_RS09280	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ADLECEL_RS09290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADLECEL_RS09310	COG0549	Belongs to the carbamate kinase family
ADLECEL_RS09320	COG2153	protein acetylation
ADLECEL_RS09335	COG0659	secondary active sulfate transmembrane transporter activity
ADLECEL_RS09340	COG1053	succinate dehydrogenase
ADLECEL_RS09360	COG0569	domain protein
ADLECEL_RS09365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADLECEL_RS09380	COG2832	Protein of unknown function (DUF454)
ADLECEL_RS09385	COG0363	glucosamine-6-phosphate deaminase activity
ADLECEL_RS09390	COG0659	secondary active sulfate transmembrane transporter activity
ADLECEL_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_RS09480	COG3657	addiction module killer protein
ADLECEL_RS09485	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADLECEL_RS09505	COG0640	Transcriptional regulator
ADLECEL_RS09510	COG2217	Heavy metal translocating P-type atpase
ADLECEL_RS09530	COG0222	ribosome binding
ADLECEL_RS09535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADLECEL_RS09540	COG2197	response regulator
ADLECEL_RS09545	COG1053	succinate dehydrogenase
ADLECEL_RS09555	COG1487	ribonuclease activity
ADLECEL_RS09565	COG0124	histidyl-tRNA synthetase
ADLECEL_RS09570	COG0473	3-isopropylmalate dehydrogenase activity
ADLECEL_RS09575	COG0066	3-isopropylmalate dehydratase activity
ADLECEL_RS09580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADLECEL_RS09590	COG0142	geranyltranstransferase activity
ADLECEL_RS09605	COG3976	FMN-binding domain protein
ADLECEL_RS09605	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_RS09615	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS09620	COG0243	molybdopterin cofactor binding
ADLECEL_RS09625	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS09630	COG2205	protein histidine kinase activity
ADLECEL_RS09665	COG1918	ferrous iron import across plasma membrane
ADLECEL_RS09665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADLECEL_RS09740	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ADLECEL_RS09790	COG1002	Type II restriction enzyme, methylase subunits
ADLECEL_RS09810	COG0582	viral genome integration into host DNA
ADLECEL_RS09855	COG1131	(ABC) transporter
ADLECEL_RS09860	COG4585	Histidine kinase
ADLECEL_RS09865	COG2197	response regulator
ADLECEL_RS09870	COG1917	Cupin 2, conserved barrel domain protein
ADLECEL_RS09870	COG4977	sequence-specific DNA binding
ADLECEL_RS09875	COG0697	spore germination
ADLECEL_RS09900	COG0488	(ABC) transporter
ADLECEL_RS09910	COG1131	(ABC) transporter
ADLECEL_RS09930	COG2197	response regulator
ADLECEL_RS09935	COG3976	FMN-binding domain protein
ADLECEL_RS09935	COG1053	succinate dehydrogenase
ADLECEL_RS09965	COG1136	(ABC) transporter
ADLECEL_RS09970	COG5002	protein histidine kinase activity
ADLECEL_RS09975	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS09980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADLECEL_RS09990	COG1309	transcriptional regulator
ADLECEL_RS10010	COG0784	Response regulator, receiver
ADLECEL_RS10010	COG2205	protein histidine kinase activity
ADLECEL_RS10015	COG0495	leucyl-tRNA aminoacylation
ADLECEL_RS10025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADLECEL_RS10035	COG0583	DNA-binding transcription factor activity
ADLECEL_RS10055	COG1592	Rubrerythrin
ADLECEL_RS10060	COG1362	aminopeptidase activity
ADLECEL_RS10065	COG0549	Belongs to the carbamate kinase family
ADLECEL_RS10070	COG2235	arginine
ADLECEL_RS10085	COG2957	Belongs to the agmatine deiminase family
ADLECEL_RS10090	COG0531	amino acid
ADLECEL_RS10110	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ADLECEL_RS10115	COG4584	PFAM Integrase catalytic
ADLECEL_RS10130	COG0549	Belongs to the carbamate kinase family
ADLECEL_RS10135	COG2957	Belongs to the agmatine deiminase family
ADLECEL_RS10140	COG0531	amino acid
ADLECEL_RS10145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_RS10165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADLECEL_RS10170	COG0477	Major facilitator Superfamily
ADLECEL_RS10190	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS10195	COG3850	Histidine kinase
ADLECEL_RS10195	COG5002	protein histidine kinase activity
ADLECEL_RS10265	COG2205	protein histidine kinase activity
ADLECEL_RS10275	COG1131	(ABC) transporter
ADLECEL_RS10280	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS10305	COG2814	Major facilitator Superfamily
ADLECEL_RS10310	COG0235	Class ii aldolase
ADLECEL_RS10315	COG1070	Carbohydrate kinase
ADLECEL_RS10315	COG4806	L-rhamnose isomerase
ADLECEL_RS10320	COG1070	Carbohydrate kinase
ADLECEL_RS10345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADLECEL_RS10350	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADLECEL_RS10370	COG0067	glutamate synthase
ADLECEL_RS10375	COG0069	glutamate synthase activity
ADLECEL_RS10390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ADLECEL_RS10395	COG2873	o-acetylhomoserine
ADLECEL_RS10485	COG1396	sequence-specific DNA binding
ADLECEL_RS10500	COG0460	homoserine dehydrogenase
ADLECEL_RS10510	COG0019	diaminopimelate decarboxylase activity
ADLECEL_RS10525	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_RS10545	COG0398	Pfam SNARE associated Golgi protein
ADLECEL_RS10560	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADLECEL_RS10565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_RS10580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADLECEL_RS10590	COG0515	serine threonine protein kinase
ADLECEL_RS10590	COG2815	serine threonine protein kinase
ADLECEL_RS10595	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADLECEL_RS10605	COG3275	phosphorelay sensor kinase activity
ADLECEL_RS10610	COG0730	response to heat
ADLECEL_RS10620	COG1162	GTPase activity
ADLECEL_RS10630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADLECEL_RS10635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADLECEL_RS10640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADLECEL_RS10650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADLECEL_RS10655	COG5002	protein histidine kinase activity
ADLECEL_RS10660	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS10670	COG1472	Belongs to the glycosyl hydrolase 3 family
ADLECEL_RS10675	COG0785	Cytochrome C biogenesis protein
ADLECEL_RS10680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADLECEL_RS10700	COG2208	phosphoserine phosphatase activity
ADLECEL_RS10700	COG2770	Histidine kinase
ADLECEL_RS10705	COG1366	Belongs to the anti-sigma-factor antagonist family
ADLECEL_RS10710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADLECEL_RS10780	COG4974	Belongs to the 'phage' integrase family
ADLECEL_RS10820	COG2239	Acts as a magnesium transporter
ADLECEL_RS10830	COG1959	2 iron, 2 sulfur cluster binding
ADLECEL_RS10835	COG1757	Na H antiporter
ADLECEL_RS10855	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADLECEL_RS10860	COG1169	isochorismate synthase
ADLECEL_RS10865	COG3830	Belongs to the UPF0237 family
ADLECEL_RS10870	COG0302	gtp cyclohydrolase
ADLECEL_RS10885	COG0708	Exodeoxyribonuclease III
ADLECEL_RS10890	COG1316	TRANSCRIPTIONal
ADLECEL_RS10905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADLECEL_RS10925	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS10930	COG0243	molybdopterin cofactor binding
ADLECEL_RS10935	COG0583	DNA-binding transcription factor activity
ADLECEL_RS10940	COG1053	succinate dehydrogenase
ADLECEL_RS10950	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_RS10965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADLECEL_RS10970	COG3189	MarR family transcriptional regulator
ADLECEL_RS10975	COG2233	PERMEase
ADLECEL_RS11000	COG3706	GGDEF domain
ADLECEL_RS11020	COG0025	NhaP-type Na H and K H
ADLECEL_RS11025	COG0519	Catalyzes the synthesis of GMP from XMP
ADLECEL_RS11085	COG1396	sequence-specific DNA binding
ADLECEL_RS11095	COG0657	acetylesterase activity
ADLECEL_RS11100	COG0454	-acetyltransferase
ADLECEL_RS11110	COG2207	Transcriptional regulator
ADLECEL_RS11110	COG3708	Transcriptional regulator
ADLECEL_RS11115	COG0456	acetyltransferase
ADLECEL_RS11120	COG0477	Major facilitator Superfamily
ADLECEL_RS11140	COG2066	Belongs to the glutaminase family
ADLECEL_RS11145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADLECEL_RS11155	COG1307	EDD domain protein, DegV family
ADLECEL_RS11160	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADLECEL_RS11190	COG1393	Belongs to the ArsC family
ADLECEL_RS11215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADLECEL_RS11240	COG0531	amino acid
ADLECEL_RS11255	COG2223	nitrite transmembrane transporter activity
ADLECEL_RS11275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_RS11280	COG1120	ATPase activity
ADLECEL_RS11305	COG3093	addiction module antidote protein HigA
ADLECEL_RS11325	COG0433	COG0433 Predicted ATPase
ADLECEL_RS11330	COG0390	transport system, permease component
ADLECEL_RS11435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADLECEL_RS11475	COG2205	protein histidine kinase activity
ADLECEL_RS11475	COG0784	Response regulator, receiver
ADLECEL_RS11485	COG3437	response regulator, receiver
ADLECEL_RS11495	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS11500	COG2205	protein histidine kinase activity
ADLECEL_RS11505	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_RS11510	COG0243	molybdopterin cofactor binding
ADLECEL_RS11560	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_RS11580	COG0765	amino acid transport
ADLECEL_RS11585	COG1126	abc transporter atp-binding protein
ADLECEL_RS11590	COG2223	nitrite transmembrane transporter activity
ADLECEL_RS11600	COG0280	phosphate acetyltransferase
ADLECEL_RS11655	COG1842	Phage shock protein A
ADLECEL_RS11685	COG0631	protein serine/threonine phosphatase activity
ADLECEL_RS11695	COG0515	serine threonine protein kinase
ADLECEL_RS11695	COG2815	serine threonine protein kinase
ADLECEL_RS11710	COG5002	protein histidine kinase activity
ADLECEL_RS11715	COG0745	RESPONSE REGULATOR receiver
ADLECEL_RS11720	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADLECEL_RS11725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADLECEL_RS11730	COG0581	inorganic phosphate transmembrane transporter activity
ADLECEL_RS11735	COG0573	inorganic phosphate transmembrane transporter activity
ADLECEL_RS11745	COG1785	Belongs to the alkaline phosphatase family
ADLECEL_RS11760	COG1328	CTP reductase activity
ADLECEL_RS11770	COG1122	ATPase activity
ADLECEL_RS11815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADLECEL_RS11830	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ADLECEL_RS11835	COG0644	oxidoreductase
ADLECEL_RS11840	COG1902	pentaerythritol trinitrate reductase activity
ADLECEL_RS11840	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADLECEL_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_RS11855	COG1053	succinate dehydrogenase
ADLECEL_RS11855	COG0431	NADPH-dependent FMN reductase
ADLECEL_RS11855	COG3976	FMN-binding domain protein
ADLECEL_RS11895	COG1053	succinate dehydrogenase
ADLECEL_RS11915	COG1047	Peptidyl-prolyl cis-trans
ADLECEL_RS11965	COG1979	alcohol dehydrogenase
ADLECEL_RS11980	COG0726	polysaccharide deacetylase
ADLECEL_RS11985	COG1045	serine acetyltransferase
ADLECEL_RS11990	COG2814	Major facilitator Superfamily
ADLECEL_RS11995	COG1253	flavin adenine dinucleotide binding
ADLECEL_RS12020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADLECEL_RS12025	COG1217	gtp-binding protein TYPA
ADLECEL_RS12055	COG4804	nuclease activity
ADLECEL_RS12105	COG3328	transposase activity
ADLECEL_RS12270	COG0270	DNA (cytosine-5-)-methyltransferase activity
ADLECEL_RS12435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADLECEL_RS12440	COG0187	DNA topoisomerase II activity