locus-tag	class	description
ATHSA_RS00010	COG1132	(ABC) transporter
ATHSA_RS00015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ATHSA_RS00035	COG1609	Transcriptional regulator
ATHSA_RS00040	COG0714	Associated with various cellular activities
ATHSA_RS00060	COG1131	(ABC) transporter
ATHSA_RS00070	COG1136	(ABC) transporter
ATHSA_RS00070	COG0577	efflux transmembrane transporter activity
ATHSA_RS00075	COG1136	(ABC) transporter
ATHSA_RS00100	COG1923	regulation of RNA biosynthetic process
ATHSA_RS00110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ATHSA_RS00115	COG0095	Lipoate-protein ligase
ATHSA_RS00120	COG0357	Ribosomal RNA small subunit methyltransferase G
ATHSA_RS00125	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS00135	COG0513	Belongs to the DEAD box helicase family
ATHSA_RS00145	COG0575	Belongs to the CDS family
ATHSA_RS00155	COG0233	cytoplasmic translational termination
ATHSA_RS00160	COG0528	UMP kinase activity
ATHSA_RS00165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATHSA_RS00185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATHSA_RS00205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATHSA_RS00210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATHSA_RS00230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATHSA_RS00235	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATHSA_RS00245	COG0572	uridine kinase
ATHSA_RS00255	COG4786	Flagellar basal body rod
ATHSA_RS00260	COG4786	Flagellar basal body rod
ATHSA_RS00270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ATHSA_RS00275	COG1706	bacterial-type flagellum-dependent cell motility
ATHSA_RS00290	COG1271	oxidase subunit
ATHSA_RS00295	COG1294	oxidase, subunit
ATHSA_RS00310	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS00325	COG1523	belongs to the glycosyl hydrolase 13 family
ATHSA_RS00335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ATHSA_RS00350	COG0203	ribosomal protein L17
ATHSA_RS00355	COG0202	RNA polymerase activity
ATHSA_RS00360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATHSA_RS00365	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATHSA_RS00370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATHSA_RS00385	COG0563	adenylate kinase activity
ATHSA_RS00390	COG0201	protein transport
ATHSA_RS00395	COG0200	Binds to the 23S rRNA
ATHSA_RS00400	COG1841	ribosomal large subunit assembly
ATHSA_RS00405	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATHSA_RS00410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATHSA_RS00415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATHSA_RS00420	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATHSA_RS00430	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATHSA_RS00435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATHSA_RS00440	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATHSA_RS00450	COG0255	Belongs to the universal ribosomal protein uL29 family
ATHSA_RS00455	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATHSA_RS00460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATHSA_RS00465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATHSA_RS00470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATHSA_RS00475	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATHSA_RS00480	COG0089	rRNA binding
ATHSA_RS00485	COG0088	Forms part of the polypeptide exit tunnel
ATHSA_RS00490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATHSA_RS00495	COG0051	transcription antitermination factor activity, RNA binding
ATHSA_RS00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATHSA_RS00505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATHSA_RS00510	COG0049	tRNA binding
ATHSA_RS00515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATHSA_RS00520	COG0438	transferase activity, transferring glycosyl groups
ATHSA_RS00535	COG2201	protein-glutamate methylesterase activity
ATHSA_RS00550	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATHSA_RS00555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATHSA_RS00560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ATHSA_RS00565	COG0802	atpase or kinase
ATHSA_RS00570	COG1073	alpha beta
ATHSA_RS00575	COG1070	Carbohydrate kinase
ATHSA_RS00610	COG1702	phosphate starvation-inducible protein PhoH
ATHSA_RS00615	COG1480	7TM receptor with intracellular HD hydrolase
ATHSA_RS00620	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATHSA_RS00645	COG0204	Acyl-transferase
ATHSA_RS00650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ATHSA_RS00655	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ATHSA_RS00660	COG1396	sequence-specific DNA binding
ATHSA_RS00675	COG1987	bacterial-type flagellum assembly
ATHSA_RS00680	COG1684	flagellar biosynthetic protein fliR
ATHSA_RS00690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATHSA_RS00695	COG1419	protein localization to endoplasmic reticulum
ATHSA_RS00700	COG0455	bacterial-type flagellum organization
ATHSA_RS00705	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ATHSA_RS00710	COG1776	CheC inhibitor of MCP methylation
ATHSA_RS00715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ATHSA_RS00725	COG1191	sigma factor activity
ATHSA_RS00735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATHSA_RS00745	COG0504	CTP synthase activity
ATHSA_RS00750	COG0647	UMP catabolic process
ATHSA_RS00755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATHSA_RS00760	COG0800	Aldolase
ATHSA_RS00765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_RS00770	COG1312	Catalyzes the dehydration of D-mannonate
ATHSA_RS00775	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS00815	COG1501	Belongs to the glycosyl hydrolase 31 family
ATHSA_RS00820	COG1472	Belongs to the glycosyl hydrolase 3 family
ATHSA_RS00830	COG1940	carbohydrate kinase activity
ATHSA_RS00835	COG1070	Carbohydrate kinase
ATHSA_RS00840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ATHSA_RS00845	COG0735	belongs to the Fur family
ATHSA_RS00850	COG0426	domain, Protein
ATHSA_RS00855	COG1528	Iron-storage protein
ATHSA_RS00860	COG2033	superoxide reductase activity
ATHSA_RS00885	COG1595	DNA-templated transcription, initiation
ATHSA_RS00890	COG0268	Binds directly to 16S ribosomal RNA
ATHSA_RS00895	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_RS00900	COG2030	dehydratase
ATHSA_RS00905	COG0180	Tryptophanyl-tRNA synthetase
ATHSA_RS00910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATHSA_RS00915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATHSA_RS00920	COG1187	pseudouridine synthase activity
ATHSA_RS00945	COG5002	protein histidine kinase activity
ATHSA_RS00950	COG1639	'signal transduction protein
ATHSA_RS00955	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATHSA_RS00960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATHSA_RS00965	COG0284	orotidine-5'-phosphate decarboxylase activity
ATHSA_RS00970	COG0167	dihydroorotate dehydrogenase activity
ATHSA_RS00985	COG0540	Belongs to the ATCase OTCase family
ATHSA_RS00990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATHSA_RS00995	COG0746	molybdenum cofactor guanylyltransferase activity
ATHSA_RS01000	COG3383	formate dehydrogenase (NAD+) activity
ATHSA_RS01005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATHSA_RS01010	COG3404	Formiminotransferase-cyclodeaminase
ATHSA_RS01015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATHSA_RS01085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATHSA_RS01100	COG0601	transmembrane transport
ATHSA_RS01105	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS01110	COG4166	transmembrane transport
ATHSA_RS01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_RS01120	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_RS01125	COG1228	amidohydrolase
ATHSA_RS01130	COG0747	negative chemotaxis
ATHSA_RS01135	COG0531	amino acid
ATHSA_RS01140	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_RS01145	COG0747	negative chemotaxis
ATHSA_RS01155	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ATHSA_RS01160	COG0277	FAD linked oxidase domain protein
ATHSA_RS01170	COG1012	belongs to the aldehyde dehydrogenase family
ATHSA_RS01175	COG3875	lactate racemase activity
ATHSA_RS01180	COG1070	Carbohydrate kinase
ATHSA_RS01185	COG4952	isomerase
ATHSA_RS01200	COG1879	ABC-type sugar transport system periplasmic component
ATHSA_RS01205	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_RS01210	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_RS01215	COG1129	ABC transporter
ATHSA_RS01240	COG1349	DNA-binding transcription factor activity
ATHSA_RS01245	COG1830	Aldolase
ATHSA_RS01255	COG3340	Belongs to the peptidase S51 family
ATHSA_RS01260	COG0768	penicillin binding
ATHSA_RS01265	COG2379	hydroxypyruvate reductase
ATHSA_RS01280	COG3264	Mechanosensitive ion channel
ATHSA_RS01280	COG1511	domain protein
ATHSA_RS01285	COG0793	Belongs to the peptidase S41A family
ATHSA_RS01285	COG4946	Tricorn protease homolog
ATHSA_RS01310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATHSA_RS01315	COG0792	nuclease activity
ATHSA_RS01320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATHSA_RS01330	COG3386	PFAM SMP-30 Gluconolaconase
ATHSA_RS01340	COG4166	transmembrane transport
ATHSA_RS01345	COG1609	Transcriptional regulator
ATHSA_RS01350	COG0656	L-ascorbic acid biosynthetic process
ATHSA_RS01355	COG0667	Aldo Keto reductase
ATHSA_RS01360	COG0667	Aldo Keto reductase
ATHSA_RS01365	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ATHSA_RS01370	COG0667	Aldo Keto reductase
ATHSA_RS01380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATHSA_RS01385	COG0750	zinc metalloprotease
ATHSA_RS01400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ATHSA_RS01400	COG2080	2 iron, 2 sulfur cluster binding
ATHSA_RS01415	COG0735	belongs to the Fur family
ATHSA_RS01420	COG0436	Aminotransferase
ATHSA_RS01440	COG0640	Transcriptional regulator
ATHSA_RS01445	COG0798	PFAM Bile acid sodium symporter
ATHSA_RS01450	COG0393	Putative heavy-metal-binding
ATHSA_RS01460	COG1131	(ABC) transporter
ATHSA_RS01465	COG1725	Transcriptional regulator
ATHSA_RS01470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATHSA_RS01480	COG0732	type I restriction modification DNA specificity domain
ATHSA_RS01485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ATHSA_RS01525	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS01530	COG0588	phosphoglycerate mutase activity
ATHSA_RS01545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_RS01550	COG4989	oxidoreductase activity
ATHSA_RS01555	COG2814	Major facilitator Superfamily
ATHSA_RS01560	COG1584	GPR1 FUN34 yaaH family protein
ATHSA_RS01565	COG0531	amino acid
ATHSA_RS01575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ATHSA_RS01580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATHSA_RS01585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATHSA_RS01595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATHSA_RS01600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATHSA_RS01605	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS01610	COG1428	Deoxynucleoside kinase
ATHSA_RS01635	COG0751	glycine-tRNA ligase activity
ATHSA_RS01640	COG0752	glycyl-tRNA synthetase alpha subunit
ATHSA_RS01645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATHSA_RS01650	COG0745	RESPONSE REGULATOR receiver
ATHSA_RS01655	COG5002	protein histidine kinase activity
ATHSA_RS01665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATHSA_RS01670	COG2359	stage V sporulation protein S
ATHSA_RS01680	COG3872	metal-dependent enzyme
ATHSA_RS01685	COG2814	Major facilitator Superfamily
ATHSA_RS01745	COG1272	protein, Hemolysin III
ATHSA_RS01750	COG1609	Transcriptional regulator
ATHSA_RS01775	COG1175	transmembrane transport
ATHSA_RS01795	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS01800	COG1175	transmembrane transport
ATHSA_RS01805	COG2182	Extracellular solute-binding protein
ATHSA_RS01825	COG1396	sequence-specific DNA binding
ATHSA_RS01850	COG0562	UDP-galactopyranose mutase
ATHSA_RS01860	COG1418	mRNA catabolic process
ATHSA_RS01880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATHSA_RS01895	COG0758	DNA mediated transformation
ATHSA_RS01915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ATHSA_RS01930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ATHSA_RS01935	COG1349	DNA-binding transcription factor activity
ATHSA_RS01940	COG0434	BtpA family
ATHSA_RS01945	COG1070	Carbohydrate kinase
ATHSA_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS01960	COG4143	(ABC) transporter
ATHSA_RS01970	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATHSA_RS01980	COG3842	ATPase activity
ATHSA_RS01985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATHSA_RS01985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATHSA_RS02005	COG0728	peptidoglycan biosynthetic process
ATHSA_RS02010	COG0148	phosphopyruvate hydratase activity
ATHSA_RS02015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATHSA_RS02020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATHSA_RS02025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATHSA_RS02030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATHSA_RS02035	COG0772	Belongs to the SEDS family
ATHSA_RS02040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATHSA_RS02045	COG0840	transmembrane signaling receptor activity
ATHSA_RS02050	COG1739	Uncharacterized protein family UPF0029
ATHSA_RS02055	COG1323	Belongs to the UPF0348 family
ATHSA_RS02065	COG1254	Belongs to the acylphosphatase family
ATHSA_RS02070	COG0561	phosphatase activity
ATHSA_RS02075	COG1776	CheC inhibitor of MCP methylation
ATHSA_RS02075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_RS02080	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_RS02105	COG1749	Flagellar hook protein flgE
ATHSA_RS02110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ATHSA_RS02130	COG2814	Major facilitator Superfamily
ATHSA_RS02135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATHSA_RS02140	COG1846	Transcriptional regulator
ATHSA_RS02145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATHSA_RS02150	COG0166	Belongs to the GPI family
ATHSA_RS02155	COG4656	Part of a membrane complex involved in electron transport
ATHSA_RS02160	COG4658	electron transport chain
ATHSA_RS02170	COG4660	Part of a membrane complex involved in electron transport
ATHSA_RS02175	COG4657	Part of a membrane complex involved in electron transport
ATHSA_RS02180	COG2878	Part of a membrane complex involved in electron transport
ATHSA_RS02180	COG1245	4Fe-4S binding domain
ATHSA_RS02200	COG0012	GTP binding
ATHSA_RS02205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ATHSA_RS02210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_RS02215	COG0784	Response regulator, receiver
ATHSA_RS02215	COG3437	response regulator, receiver
ATHSA_RS02225	COG1342	Belongs to the UPF0251 family
ATHSA_RS02230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_RS02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_RS02235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATHSA_RS02245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ATHSA_RS02250	COG0653	protein targeting
ATHSA_RS02255	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATHSA_RS02270	COG1744	ABC transporter substrate-binding protein PnrA-like
ATHSA_RS02275	COG0584	glycerophosphoryl diester phosphodiesterase
ATHSA_RS02300	COG1830	Aldolase
ATHSA_RS02320	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATHSA_RS02325	COG0720	synthase
ATHSA_RS02350	COG0542	response to heat
ATHSA_RS02355	COG0071	Belongs to the small heat shock protein (HSP20) family
ATHSA_RS02360	COG0443	Heat shock 70 kDa protein
ATHSA_RS02375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATHSA_RS02380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATHSA_RS02385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATHSA_RS02390	COG1561	YicC-like family, N-terminal region
ATHSA_RS02395	COG2052	Domain of unknown function (DUF370)
ATHSA_RS02400	COG0194	GDP metabolic process
ATHSA_RS02405	COG1758	RNA polymerase activity
ATHSA_RS02410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ATHSA_RS02415	COG3634	alkyl hydroperoxide reductase activity
ATHSA_RS02420	COG0492	ferredoxin-NADP+ reductase activity
ATHSA_RS02460	COG4166	transmembrane transport
ATHSA_RS02465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ATHSA_RS02470	COG1105	Belongs to the carbohydrate kinase PfkB family
ATHSA_RS02475	COG0116	Belongs to the methyltransferase superfamily
ATHSA_RS02480	COG1045	serine acetyltransferase
ATHSA_RS02485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ATHSA_RS02490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATHSA_RS02490	COG0519	Catalyzes the synthesis of GMP from XMP
ATHSA_RS02500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATHSA_RS02520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATHSA_RS02525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATHSA_RS02530	COG0740	serine-type endopeptidase activity
ATHSA_RS02535	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATHSA_RS02540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ATHSA_RS02545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ATHSA_RS02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATHSA_RS02555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATHSA_RS02560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ATHSA_RS02565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ATHSA_RS02570	COG0459	protein refolding
ATHSA_RS02575	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS02635	COG2235	arginine
ATHSA_RS02640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATHSA_RS02660	COG0564	pseudouridine synthase activity
ATHSA_RS02665	COG0671	phosphoesterase, PA-phosphatase related
ATHSA_RS02670	COG1420	regulation of RNA biosynthetic process
ATHSA_RS02675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATHSA_RS02680	COG0484	heat shock protein binding
ATHSA_RS02705	COG3842	ATPase activity
ATHSA_RS02735	COG1418	mRNA catabolic process
ATHSA_RS02740	COG1126	abc transporter atp-binding protein
ATHSA_RS02750	COG1126	abc transporter atp-binding protein
ATHSA_RS02755	COG0765	amino acid transport
ATHSA_RS02770	COG0037	tRNA processing
ATHSA_RS02775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATHSA_RS02785	COG0745	RESPONSE REGULATOR receiver
ATHSA_RS02790	COG5002	protein histidine kinase activity
ATHSA_RS02800	COG2151	metal-sulfur cluster biosynthetic enzyme
ATHSA_RS02810	COG3956	TIGRFAM MazG family protein
ATHSA_RS02815	COG1392	Phosphate transport regulator
ATHSA_RS02825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ATHSA_RS02830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ATHSA_RS02840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ATHSA_RS02850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_RS02860	COG1307	EDD domain protein, DegV family
ATHSA_RS02865	COG1970	mechanosensitive ion channel activity
ATHSA_RS02875	COG1175	transmembrane transport
ATHSA_RS02880	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS02885	COG0084	hydrolase, TatD family'
ATHSA_RS02890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATHSA_RS02925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATHSA_RS02935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATHSA_RS02940	COG0250	Participates in transcription elongation, termination and antitermination
ATHSA_RS02945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATHSA_RS02950	COG0081	regulation of translation
ATHSA_RS02955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATHSA_RS02960	COG0222	ribosome binding
ATHSA_RS02965	COG0085	RNA polymerase activity
ATHSA_RS02970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATHSA_RS03020	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_RS03030	COG1242	4 iron, 4 sulfur cluster binding
ATHSA_RS03035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ATHSA_RS03055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATHSA_RS03070	COG0776	regulation of translation
ATHSA_RS03085	COG0450	alkyl hydroperoxide reductase
ATHSA_RS03090	COG1914	H( )-stimulated, divalent metal cation uptake system
ATHSA_RS03105	COG1677	Flagellar hook-basal body complex protein FliE
ATHSA_RS03110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ATHSA_RS03115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATHSA_RS03155	COG1598	PFAM Uncharacterised protein family UPF0150
ATHSA_RS03185	COG1598	PFAM Uncharacterised protein family UPF0150
ATHSA_RS03210	COG3852	Histidine kinase
ATHSA_RS03220	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ATHSA_RS03225	COG0571	ribonuclease III activity
ATHSA_RS03235	COG1196	nuclear chromosome segregation
ATHSA_RS03240	COG0481	GTPase activity
ATHSA_RS03250	COG1515	deoxyribonuclease V activity
ATHSA_RS03280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATHSA_RS03290	COG2814	Major facilitator Superfamily
ATHSA_RS03295	COG0138	bifunctional purine biosynthesis protein purh
ATHSA_RS03300	COG0835	chemotaxis
ATHSA_RS03305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ATHSA_RS03315	COG0489	protein tyrosine kinase activity
ATHSA_RS03325	COG1214	PFAM Peptidase M22, glycoprotease
ATHSA_RS03335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATHSA_RS03360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ATHSA_RS03370	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS03390	COG1349	DNA-binding transcription factor activity
ATHSA_RS03410	COG1175	transmembrane transport
ATHSA_RS03415	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS03420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ATHSA_RS03430	COG3250	beta-galactosidase activity
ATHSA_RS03435	COG1486	melibiose metabolic process
ATHSA_RS03465	COG0569	domain protein
ATHSA_RS03470	COG0569	domain protein
ATHSA_RS03475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ATHSA_RS03490	COG4191	Histidine kinase
ATHSA_RS03495	COG2204	response regulator
ATHSA_RS03505	COG1228	amidohydrolase
ATHSA_RS03515	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_RS03540	COG1362	aminopeptidase activity
ATHSA_RS03545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATHSA_RS03545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ATHSA_RS03565	COG0356	it plays a direct role in the translocation of protons across the membrane
ATHSA_RS03570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATHSA_RS03575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATHSA_RS03585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATHSA_RS03590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATHSA_RS03595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATHSA_RS03600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATHSA_RS03610	COG2078	PFAM AMMECR1 domain protein
ATHSA_RS03620	COG2894	cell division
ATHSA_RS03630	COG0432	Pfam Uncharacterised protein family UPF0047
ATHSA_RS03645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATHSA_RS03650	COG2362	D-Aminopeptidase
ATHSA_RS03655	COG0482	sulfurtransferase activity
ATHSA_RS03675	COG1543	Belongs to the glycosyl hydrolase 57 family
ATHSA_RS03725	COG0822	iron-sulfur transferase activity
ATHSA_RS03730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATHSA_RS03735	COG0719	Fe-S assembly protein
ATHSA_RS03740	COG0719	Fe-S assembly protein
ATHSA_RS03745	COG0396	ATPase activity
ATHSA_RS03760	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS03765	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS03770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_RS03780	COG1268	BioY protein
ATHSA_RS03785	COG0488	(ABC) transporter
ATHSA_RS03790	COG2986	histidine ammonia-lyase
ATHSA_RS03795	COG0557	exoribonuclease II activity
ATHSA_RS03800	COG1937	Protein conserved in bacteria
ATHSA_RS03805	COG0793	Belongs to the peptidase S41A family
ATHSA_RS03805	COG3409	Peptidoglycan-binding domain 1 protein
ATHSA_RS03815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATHSA_RS03820	COG0228	four-way junction DNA binding
ATHSA_RS03825	COG1837	Belongs to the UPF0109 family
ATHSA_RS03830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATHSA_RS03835	COG0336	Belongs to the RNA methyltransferase TrmD family
ATHSA_RS03840	COG4752	Belongs to the RNA methyltransferase TrmD family
ATHSA_RS03845	COG0335	large ribosomal subunit rRNA binding
ATHSA_RS03855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ATHSA_RS03860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_RS03865	COG0850	regulation of cytokinetic process
ATHSA_RS03870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATHSA_RS03885	COG1555	photosystem II stabilization
ATHSA_RS03910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ATHSA_RS03915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATHSA_RS03925	COG0149	triose-phosphate isomerase activity
ATHSA_RS03930	COG0126	phosphoglycerate kinase activity
ATHSA_RS03930	COG0149	triose-phosphate isomerase activity
ATHSA_RS03940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ATHSA_RS03945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATHSA_RS03955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATHSA_RS03970	COG2136	Putative SAM-dependent methyltransferase
ATHSA_RS03970	COG2521	methyltransferase
ATHSA_RS03975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATHSA_RS03980	COG1923	regulation of RNA biosynthetic process
ATHSA_RS03985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATHSA_RS03995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATHSA_RS04000	COG0445	tRNA wobble uridine modification
ATHSA_RS04005	COG1227	inorganic diphosphatase activity
ATHSA_RS04005	COG0517	IMP dehydrogenase activity
ATHSA_RS04050	COG2208	phosphoserine phosphatase activity
ATHSA_RS04070	COG0248	Ppx GppA phosphatase
ATHSA_RS04075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATHSA_RS04095	COG0745	RESPONSE REGULATOR receiver
ATHSA_RS04100	COG0784	Response regulator, receiver
ATHSA_RS04100	COG2205	protein histidine kinase activity
ATHSA_RS04105	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ATHSA_RS04110	COG1704	LemA family
ATHSA_RS04115	COG0191	fructose-bisphosphate aldolase activity
ATHSA_RS04120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATHSA_RS04125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATHSA_RS04130	COG1827	regulation of RNA biosynthetic process
ATHSA_RS04135	COG0477	Major facilitator Superfamily
ATHSA_RS04155	COG3852	Histidine kinase
ATHSA_RS04170	COG0517	IMP dehydrogenase activity
ATHSA_RS04170	COG1125	glycine betaine transport
ATHSA_RS04180	COG4166	transmembrane transport
ATHSA_RS04185	COG0601	transmembrane transport
ATHSA_RS04195	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS04200	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS04215	COG1449	Belongs to the glycosyl hydrolase 57 family
ATHSA_RS04220	COG1530	ribonuclease E activity
ATHSA_RS04225	COG1338	Plays a role in the flagellum-specific transport system
ATHSA_RS04235	COG2201	protein-glutamate methylesterase activity
ATHSA_RS04240	COG0835	chemotaxis
ATHSA_RS04245	COG0643	Histidine kinase
ATHSA_RS04245	COG2198	Histidine kinase
ATHSA_RS04285	COG0483	inositol monophosphate 1-phosphatase activity
ATHSA_RS04290	COG0072	phenylalanine-tRNA ligase activity
ATHSA_RS04290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_RS04295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATHSA_RS04300	COG0785	Cytochrome C biogenesis protein
ATHSA_RS04315	COG0484	heat shock protein binding
ATHSA_RS04330	COG0366	Alpha amylase catalytic
ATHSA_RS04335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ATHSA_RS04340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATHSA_RS04345	COG3481	metal-dependent phosphohydrolase, HD sub domain
ATHSA_RS04350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATHSA_RS04355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATHSA_RS04375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ATHSA_RS04380	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ATHSA_RS04385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATHSA_RS04390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ATHSA_RS04400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ATHSA_RS04460	COG0842	Transport permease protein
ATHSA_RS04465	COG4555	ABC transporter
ATHSA_RS04495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATHSA_RS04505	COG2172	sigma factor antagonist activity
ATHSA_RS04510	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ATHSA_RS04515	COG2770	Histidine kinase
ATHSA_RS04515	COG3437	response regulator, receiver
ATHSA_RS04520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATHSA_RS04525	COG1765	OsmC-like protein
ATHSA_RS04540	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ATHSA_RS04545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATHSA_RS04555	COG0367	asparagine synthase
ATHSA_RS04565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATHSA_RS04575	COG1278	Cold shock
ATHSA_RS04590	COG1653	transport
ATHSA_RS04605	COG2814	Major facilitator Superfamily
ATHSA_RS04610	COG4166	transmembrane transport
ATHSA_RS04615	COG0601	transmembrane transport
ATHSA_RS04625	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS04630	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS04645	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATHSA_RS04650	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATHSA_RS04650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATHSA_RS04660	COG0768	penicillin binding
ATHSA_RS04670	COG0275	rRNA processing
ATHSA_RS04675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATHSA_RS04685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATHSA_RS04690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATHSA_RS04695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATHSA_RS04700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATHSA_RS04705	COG1461	Dihydroxyacetone kinase
ATHSA_RS04715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATHSA_RS04720	COG1722	exodeoxyribonuclease VII activity
ATHSA_RS04725	COG1570	exodeoxyribonuclease VII activity
ATHSA_RS04730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATHSA_RS04735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ATHSA_RS04745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATHSA_RS04750	COG0006	proline dipeptidase activity
ATHSA_RS04760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATHSA_RS04760	COG0574	Belongs to the PEP-utilizing enzyme family
ATHSA_RS04765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATHSA_RS04775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATHSA_RS04800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATHSA_RS04800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATHSA_RS04805	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATHSA_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATHSA_RS04815	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ATHSA_RS04820	COG0512	Glutamine amidotransferase of anthranilate synthase
ATHSA_RS04820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATHSA_RS04840	COG0135	phosphoribosylanthranilate isomerase activity
ATHSA_RS04855	COG0497	DNA recombination
ATHSA_RS04860	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_RS04875	COG5012	cobalamin binding
ATHSA_RS04905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATHSA_RS04910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATHSA_RS04920	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATHSA_RS04925	COG0305	Participates in initiation and elongation during chromosome replication
ATHSA_RS04935	COG0704	Plays a role in the regulation of phosphate uptake
ATHSA_RS04945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATHSA_RS04950	COG0581	inorganic phosphate transmembrane transporter activity
ATHSA_RS04955	COG0573	inorganic phosphate transmembrane transporter activity
ATHSA_RS04965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATHSA_RS04975	COG0427	acetyl-CoA hydrolase
ATHSA_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS04985	COG0183	Belongs to the thiolase family
ATHSA_RS05025	COG0477	Major facilitator Superfamily
ATHSA_RS05030	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_RS05035	COG1151	hydroxylamine reductase activity
ATHSA_RS05045	COG2046	Belongs to the sulfate adenylyltransferase family
ATHSA_RS05055	COG0529	Catalyzes the synthesis of activated sulfate
ATHSA_RS05060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATHSA_RS05080	COG1157	protein secretion by the type III secretion system
ATHSA_RS05085	COG1592	Rubrerythrin
ATHSA_RS05090	COG0531	amino acid
ATHSA_RS05100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ATHSA_RS05105	COG1660	Displays ATPase and GTPase activities
ATHSA_RS05125	COG1085	galactose-1-phosphate uridylyltransferase
ATHSA_RS05130	COG0297	glycogen (starch) synthase activity
ATHSA_RS05140	COG1178	ABC-type Fe3 transport system permease component
ATHSA_RS05170	COG1653	transport
ATHSA_RS05180	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS05190	COG3459	Glycosyltransferase 36 associated
ATHSA_RS05215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATHSA_RS05220	COG0083	homoserine kinase activity
ATHSA_RS05230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATHSA_RS05235	COG0765	amino acid transport
ATHSA_RS05250	COG0110	maltose O-acetyltransferase activity
ATHSA_RS05260	COG1122	ATPase activity
ATHSA_RS05265	COG1122	ATPase activity
ATHSA_RS05270	COG2813	Specifically methylates the guanine in position
ATHSA_RS05280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ATHSA_RS05285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATHSA_RS05295	COG5002	protein histidine kinase activity
ATHSA_RS05305	COG0704	Plays a role in the regulation of phosphate uptake
ATHSA_RS05310	COG0840	transmembrane signaling receptor activity
ATHSA_RS05315	COG1490	D-aminoacyl-tRNA deacylase activity
ATHSA_RS05320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATHSA_RS05370	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS05375	COG1175	transmembrane transport
ATHSA_RS05380	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS05385	COG1349	DNA-binding transcription factor activity
ATHSA_RS05400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_RS05410	COG1131	(ABC) transporter
ATHSA_RS05420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATHSA_RS05450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATHSA_RS05480	COG0511	ligase activity, forming carbon-carbon bonds
ATHSA_RS05490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATHSA_RS05495	COG0346	lactoylglutathione lyase activity
ATHSA_RS05505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATHSA_RS05510	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ATHSA_RS05525	COG1335	isochorismatase
ATHSA_RS05535	COG1131	(ABC) transporter
ATHSA_RS05545	COG0698	ribose 5-phosphate isomerase
ATHSA_RS05555	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ATHSA_RS05560	COG0193	aminoacyl-tRNA hydrolase activity
ATHSA_RS05565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ATHSA_RS05570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATHSA_RS05575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATHSA_RS05580	COG0632	four-way junction helicase activity
ATHSA_RS05585	COG0285	dihydrofolate synthase activity
ATHSA_RS05590	COG0525	valine-tRNA ligase activity
ATHSA_RS05605	COG1278	Cold shock
ATHSA_RS05610	COG0735	belongs to the Fur family
ATHSA_RS05620	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS05625	COG1175	transmembrane transport
ATHSA_RS05645	COG1098	S1 RNA binding domain
ATHSA_RS05650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATHSA_RS05660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATHSA_RS05665	COG0509	glycine decarboxylation via glycine cleavage system
ATHSA_RS05670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ATHSA_RS05675	COG0156	8-amino-7-oxononanoate synthase activity
ATHSA_RS05680	COG1063	alcohol dehydrogenase
ATHSA_RS05705	COG1141	Ferredoxin
ATHSA_RS05720	COG0617	tRNA 3'-terminal CCA addition
ATHSA_RS05735	COG1131	(ABC) transporter
ATHSA_RS05740	COG1469	GTP cyclohydrolase I activity
ATHSA_RS05760	COG1477	protein flavinylation
ATHSA_RS05770	COG0424	maF-like protein
ATHSA_RS05780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ATHSA_RS05780	COG1918	ferrous iron import across plasma membrane
ATHSA_RS05810	COG2267	carboxylic ester hydrolase activity
ATHSA_RS05830	COG2359	stage V sporulation protein S
ATHSA_RS05860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ATHSA_RS05865	COG1040	competence protein
ATHSA_RS05940	COG1573	uracil-dna glycosylase
ATHSA_RS05945	COG0124	histidyl-tRNA synthetase
ATHSA_RS05950	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATHSA_RS05955	COG5012	cobalamin binding
ATHSA_RS05965	COG2203	Gaf domain
ATHSA_RS05965	COG2199	diguanylate cyclase activity
ATHSA_RS05975	COG0667	Aldo Keto reductase
ATHSA_RS05980	COG1575	Belongs to the MenA family. Type 1 subfamily
ATHSA_RS05985	COG1252	NADH dehydrogenase
ATHSA_RS05990	COG0655	NAD(P)H dehydrogenase (quinone) activity
ATHSA_RS06015	COG0346	lactoylglutathione lyase activity
ATHSA_RS06020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_RS06025	COG0438	transferase activity, transferring glycosyl groups
ATHSA_RS06045	COG0438	transferase activity, transferring glycosyl groups
ATHSA_RS06055	COG0297	glycogen (starch) synthase activity
ATHSA_RS06060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ATHSA_RS06105	COG0592	DNA-directed DNA polymerase activity
ATHSA_RS06110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATHSA_RS06115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATHSA_RS06120	COG2045	Belongs to the ComB family
ATHSA_RS06125	COG0741	lytic transglycosylase activity
ATHSA_RS06130	COG1078	dGTPase activity
ATHSA_RS06145	COG0811	peptide transport
ATHSA_RS06150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATHSA_RS06155	COG1394	ATPase activity, coupled to movement of substances
ATHSA_RS06160	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ATHSA_RS06165	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ATHSA_RS06185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATHSA_RS06190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATHSA_RS06195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATHSA_RS06200	COG3829	transcription factor binding
ATHSA_RS06200	COG3290	protein histidine kinase activity
ATHSA_RS06205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATHSA_RS06215	COG2255	four-way junction helicase activity
ATHSA_RS06220	COG0017	Asparaginyl-tRNA synthetase
ATHSA_RS06240	COG0602	queuosine metabolic process
ATHSA_RS06285	COG0004	ammonium transporteR
ATHSA_RS06305	COG4974	Belongs to the 'phage' integrase family
ATHSA_RS06310	COG1024	Enoyl-CoA hydratase
ATHSA_RS06325	COG2814	Major facilitator Superfamily
ATHSA_RS06350	COG0656	L-ascorbic acid biosynthetic process
ATHSA_RS06360	COG0346	lactoylglutathione lyase activity
ATHSA_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS06385	COG1506	peptidase
ATHSA_RS06385	COG0823	Involved in the tonB-independent uptake of proteins
ATHSA_RS06385	COG4946	Tricorn protease homolog
ATHSA_RS06390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ATHSA_RS06395	COG0594	ribonuclease P activity
ATHSA_RS06400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATHSA_RS06405	COG0706	membrane insertase activity
ATHSA_RS06410	COG1847	R3H domain protein
ATHSA_RS06420	COG1228	amidohydrolase
ATHSA_RS06425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ATHSA_RS06430	COG4535	Mg2 and Co2 transporter CorC
ATHSA_RS06460	COG0363	glucosamine-6-phosphate deaminase activity
ATHSA_RS06465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATHSA_RS06470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATHSA_RS06475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ATHSA_RS06485	COG0436	Aminotransferase
ATHSA_RS06490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATHSA_RS06495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATHSA_RS06500	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATHSA_RS06500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATHSA_RS06510	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ATHSA_RS06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATHSA_RS06525	COG0604	alcohol dehydrogenase
ATHSA_RS06530	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS06535	COG1175	transmembrane transport
ATHSA_RS06550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ATHSA_RS06555	COG2211	Major facilitator Superfamily
ATHSA_RS06565	COG5001	Diguanylate cyclase
ATHSA_RS06565	COG1716	ATPase activity
ATHSA_RS06580	COG0584	glycerophosphoryl diester phosphodiesterase
ATHSA_RS06595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ATHSA_RS06600	COG1940	carbohydrate kinase activity
ATHSA_RS06610	COG0626	cystathionine gamma-synthase activity
ATHSA_RS06615	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS06625	COG1653	transport
ATHSA_RS06630	COG1940	carbohydrate kinase activity
ATHSA_RS06650	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS06655	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS06665	COG0601	transmembrane transport
ATHSA_RS06670	COG0747	negative chemotaxis
ATHSA_RS06675	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ATHSA_RS06690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATHSA_RS06700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ATHSA_RS06705	COG1160	GTP binding
ATHSA_RS06710	COG0539	negative regulation of cytoplasmic translation
ATHSA_RS06710	COG2183	response to ionizing radiation
ATHSA_RS06715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATHSA_RS06720	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATHSA_RS06725	COG1366	Belongs to the anti-sigma-factor antagonist family
ATHSA_RS06730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ATHSA_RS06755	COG1937	Protein conserved in bacteria
ATHSA_RS06795	COG2226	methyltransferase
ATHSA_RS06800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATHSA_RS06805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATHSA_RS06810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ATHSA_RS06815	COG2205	protein histidine kinase activity
ATHSA_RS06820	COG0477	Major facilitator Superfamily
ATHSA_RS06830	COG0778	Nitroreductase
ATHSA_RS06845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATHSA_RS06855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATHSA_RS06860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ATHSA_RS06870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ATHSA_RS06875	COG1728	Protein conserved in bacteria
ATHSA_RS06880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATHSA_RS06885	COG1774	PSP1 C-terminal conserved region
ATHSA_RS06890	COG0343	queuine tRNA-ribosyltransferase activity
ATHSA_RS06895	COG0489	protein tyrosine kinase activity
ATHSA_RS06900	COG0442	prolyl-tRNA aminoacylation
ATHSA_RS06905	COG0552	protein localization to endoplasmic reticulum
ATHSA_RS06935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATHSA_RS06940	COG0416	fatty acid biosynthetic process
ATHSA_RS06945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_RS06950	COG0799	negative regulation of ribosome biogenesis
ATHSA_RS06955	COG0495	leucyl-tRNA aminoacylation
ATHSA_RS06960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ATHSA_RS06970	COG0583	DNA-binding transcription factor activity
ATHSA_RS06975	COG3842	ATPase activity
ATHSA_RS06980	COG0366	Alpha amylase catalytic
ATHSA_RS06985	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATHSA_RS06990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATHSA_RS06995	COG1607	acyl-coa hydrolase
ATHSA_RS07000	COG3246	L-lysine catabolic process to acetate
ATHSA_RS07005	COG1862	Preprotein translocase
ATHSA_RS07010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATHSA_RS07015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATHSA_RS07025	COG0237	dephospho-CoA kinase activity
ATHSA_RS07030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATHSA_RS07035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATHSA_RS07040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATHSA_RS07040	COG0519	Catalyzes the synthesis of GMP from XMP
ATHSA_RS07045	COG0154	amidase activity
ATHSA_RS07050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATHSA_RS07055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATHSA_RS07060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATHSA_RS07060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATHSA_RS07065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATHSA_RS07065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATHSA_RS07095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATHSA_RS07115	COG3328	transposase activity
ATHSA_RS07130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATHSA_RS07160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATHSA_RS07165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATHSA_RS07170	COG0196	riboflavin kinase activity
ATHSA_RS07180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATHSA_RS07185	COG1185	polyribonucleotide nucleotidyltransferase activity
ATHSA_RS07190	COG0612	Peptidase, M16
ATHSA_RS07195	COG3437	response regulator, receiver
ATHSA_RS07210	COG1834	amidinotransferase
ATHSA_RS07220	COG1473	amidohydrolase
ATHSA_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS07240	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ATHSA_RS07275	COG1131	(ABC) transporter
ATHSA_RS07280	COG0842	Transport permease protein
ATHSA_RS07290	COG2096	Adenosyltransferase
ATHSA_RS07295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_RS07300	COG0438	transferase activity, transferring glycosyl groups
ATHSA_RS07310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATHSA_RS07320	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ATHSA_RS07325	COG0556	nucleotide-excision repair
ATHSA_RS07330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATHSA_RS07345	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ATHSA_RS07350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ATHSA_RS07355	COG4166	transmembrane transport
ATHSA_RS07360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATHSA_RS07365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATHSA_RS07380	COG0577	efflux transmembrane transporter activity
ATHSA_RS07380	COG1136	(ABC) transporter
ATHSA_RS07385	COG0322	excinuclease ABC activity
ATHSA_RS07390	COG1435	thymidine kinase activity
ATHSA_RS07400	COG0174	glutamine synthetase
ATHSA_RS07405	COG1012	belongs to the aldehyde dehydrogenase family
ATHSA_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATHSA_RS07425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATHSA_RS07425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATHSA_RS07445	COG0582	viral genome integration into host DNA
ATHSA_RS07450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATHSA_RS07475	COG4221	oxidoreductase activity
ATHSA_RS07480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ATHSA_RS07485	COG1027	Aspartate ammonia-lyase
ATHSA_RS07490	COG1760	l-serine dehydratase
ATHSA_RS07495	COG1760	l-serine dehydratase
ATHSA_RS07505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATHSA_RS07510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATHSA_RS07515	COG2171	N-acyltransferase activity
ATHSA_RS07520	COG0527	aspartate kinase activity
ATHSA_RS07525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATHSA_RS07530	COG1473	amidohydrolase
ATHSA_RS07545	COG0642	Histidine kinase
ATHSA_RS07550	COG2814	Major facilitator Superfamily
ATHSA_RS07575	COG1136	(ABC) transporter
ATHSA_RS07615	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ATHSA_RS07640	COG0463	Glycosyl transferase, family 2
ATHSA_RS07645	COG0170	dolichyl monophosphate biosynthetic process
ATHSA_RS07670	COG1523	belongs to the glycosyl hydrolase 13 family
ATHSA_RS07675	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ATHSA_RS07710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATHSA_RS07845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATHSA_RS07850	COG0673	inositol 2-dehydrogenase activity
ATHSA_RS07860	COG0646	methionine synthase
ATHSA_RS07860	COG1410	methionine synthase
ATHSA_RS07865	COG1122	ATPase activity
ATHSA_RS07885	COG1131	(ABC) transporter
ATHSA_RS07890	COG0747	negative chemotaxis
ATHSA_RS07905	COG1863	multisubunit Na H antiporter MnhE subunit
ATHSA_RS07925	COG2111	Na H antiporter
ATHSA_RS07925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATHSA_RS07935	COG0651	ATP synthesis coupled electron transport
ATHSA_RS07940	COG1007	ATP synthesis coupled electron transport
ATHSA_RS07945	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ATHSA_RS07950	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATHSA_RS07960	COG0649	NAD binding
ATHSA_RS07965	COG0493	'glutamate synthase
ATHSA_RS07970	COG0543	2 iron, 2 sulfur cluster binding
ATHSA_RS07980	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS07985	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS08000	COG0747	negative chemotaxis
ATHSA_RS08005	COG1307	EDD domain protein, DegV family
ATHSA_RS08015	COG0437	4 iron, 4 sulfur cluster binding
ATHSA_RS08020	COG0640	Transcriptional regulator
ATHSA_RS08035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATHSA_RS08040	COG3426	butyrate kinase activity
ATHSA_RS08045	COG0280	phosphate acetyltransferase
ATHSA_RS08050	COG3426	butyrate kinase activity
ATHSA_RS08080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATHSA_RS08085	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATHSA_RS08090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATHSA_RS08100	COG0303	'Molybdopterin
ATHSA_RS08105	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATHSA_RS08110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ATHSA_RS08115	COG1085	galactose-1-phosphate uridylyltransferase
ATHSA_RS08120	COG3345	alpha-galactosidase
ATHSA_RS08135	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS08140	COG1175	transmembrane transport
ATHSA_RS08150	COG1609	Transcriptional regulator
ATHSA_RS08155	COG0360	Binds together with S18 to 16S ribosomal RNA
ATHSA_RS08160	COG0629	single-stranded DNA binding
ATHSA_RS08170	COG0359	binds to the 23S rRNA
ATHSA_RS08175	COG1234	tRNA 3'-trailer cleavage
ATHSA_RS08205	COG1058	Belongs to the CinA family
ATHSA_RS08205	COG1546	Belongs to the CinA family
ATHSA_RS08210	COG0494	nUDIX hydrolase
ATHSA_RS08220	COG0728	peptidoglycan biosynthetic process
ATHSA_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_RS08245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATHSA_RS08255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATHSA_RS08270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ATHSA_RS08275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_RS08300	COG1175	transmembrane transport
ATHSA_RS08310	COG0371	Dehydrogenase
ATHSA_RS08325	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS08330	COG1175	transmembrane transport
ATHSA_RS08340	COG2160	L-arabinose isomerase activity
ATHSA_RS08350	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ATHSA_RS08355	COG0747	negative chemotaxis
ATHSA_RS08360	COG0601	transmembrane transport
ATHSA_RS08365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_RS08370	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS08375	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS08380	COG2814	Major facilitator Superfamily
ATHSA_RS08385	COG3876	Protein conserved in bacteria
ATHSA_RS08400	COG1472	Belongs to the glycosyl hydrolase 3 family
ATHSA_RS08410	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ATHSA_RS08415	COG2188	Transcriptional regulator
ATHSA_RS08425	COG0791	NLP P60 protein
ATHSA_RS08430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATHSA_RS08440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATHSA_RS08445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ATHSA_RS08450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATHSA_RS08455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATHSA_RS08460	COG0358	DNA primase activity
ATHSA_RS08465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATHSA_RS08475	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATHSA_RS08485	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ATHSA_RS08490	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS08495	COG1175	transmembrane transport
ATHSA_RS08510	COG1609	Transcriptional regulator
ATHSA_RS08515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ATHSA_RS08520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATHSA_RS08525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATHSA_RS08530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATHSA_RS08540	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_RS08555	COG1129	ABC transporter
ATHSA_RS08560	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_RS08565	COG1879	ABC-type sugar transport system periplasmic component
ATHSA_RS08575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATHSA_RS08590	COG1940	carbohydrate kinase activity
ATHSA_RS08605	COG1994	Peptidase M50
ATHSA_RS08610	COG0564	pseudouridine synthase activity
ATHSA_RS08620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ATHSA_RS08645	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ATHSA_RS08650	COG1691	(AIR) carboxylase
ATHSA_RS08655	COG1606	tRNA processing
ATHSA_RS08675	COG1959	2 iron, 2 sulfur cluster binding
ATHSA_RS08685	COG1773	rubredoxin
ATHSA_RS08690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATHSA_RS08695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ATHSA_RS08705	COG3579	cysteine-type endopeptidase activity
ATHSA_RS08710	COG3706	GGDEF domain
ATHSA_RS08715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATHSA_RS08725	COG2264	protein methyltransferase activity
ATHSA_RS08750	COG1162	GTPase activity
ATHSA_RS08755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATHSA_RS08760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATHSA_RS08765	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATHSA_RS08765	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATHSA_RS08775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ATHSA_RS08805	COG1703	isobutyryl-CoA mutase activity
ATHSA_RS08810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_RS08810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_RS08815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_RS08815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_RS08820	COG0587	DNA-directed DNA polymerase activity
ATHSA_RS08825	COG1136	(ABC) transporter
ATHSA_RS08840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATHSA_RS08845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ATHSA_RS08850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ATHSA_RS08855	COG1984	allophanate hydrolase subunit 2
ATHSA_RS08860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_RS08865	COG2313	pseudouridylate synthase activity
ATHSA_RS08870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ATHSA_RS08875	COG1334	flagellar protein FlaG
ATHSA_RS08885	COG0438	transferase activity, transferring glycosyl groups
ATHSA_RS08910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ATHSA_RS08915	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATHSA_RS08925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATHSA_RS08930	COG2264	protein methyltransferase activity
ATHSA_RS08945	COG1193	negative regulation of DNA recombination
ATHSA_RS08955	COG0617	tRNA 3'-terminal CCA addition
ATHSA_RS08955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ATHSA_RS08955	COG3620	sequence-specific DNA binding
ATHSA_RS08965	COG0254	rRNA binding
ATHSA_RS08970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATHSA_RS08975	COG2414	aldehyde ferredoxin oxidoreductase
ATHSA_RS08995	COG0280	phosphate acetyltransferase
ATHSA_RS09000	COG0019	diaminopimelate decarboxylase activity
ATHSA_RS09005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATHSA_RS09010	COG1067	ATP-dependent peptidase activity
ATHSA_RS09020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATHSA_RS09025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATHSA_RS09030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATHSA_RS09045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATHSA_RS09055	COG0205	6-phosphofructokinase activity
ATHSA_RS09060	COG0469	pyruvate kinase activity
ATHSA_RS09070	COG0205	6-phosphofructokinase activity
ATHSA_RS09075	COG0586	Pfam SNARE associated Golgi protein
ATHSA_RS09080	COG2770	Histidine kinase
ATHSA_RS09080	COG3437	response regulator, receiver
ATHSA_RS09085	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_RS09100	COG0052	Belongs to the universal ribosomal protein uS2 family
ATHSA_RS09110	COG1653	transport
ATHSA_RS09115	COG1175	transmembrane transport
ATHSA_RS09120	COG0395	ABC-type sugar transport system, permease component
ATHSA_RS09125	COG4948	Mandelate Racemase Muconate Lactonizing
ATHSA_RS09135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATHSA_RS09150	COG0366	Alpha amylase catalytic
ATHSA_RS09155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ATHSA_RS09160	COG2003	Belongs to the UPF0758 family
ATHSA_RS09170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATHSA_RS09170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATHSA_RS09185	COG1278	Cold shock
ATHSA_RS09220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ATHSA_RS09225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATHSA_RS09230	COG0215	cysteine-tRNA ligase activity
ATHSA_RS09240	COG0187	DNA topoisomerase II activity
ATHSA_RS09250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ATHSA_RS09255	COG2176	DNA-directed DNA polymerase activity
ATHSA_RS09315	COG2204	response regulator
ATHSA_RS09325	COG1121	(ABC) transporter
ATHSA_RS09330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATHSA_RS09350	COG2894	cell division
ATHSA_RS09360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATHSA_RS09360	COG0731	radical SAM domain protein
ATHSA_RS09365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATHSA_RS09380	COG3250	beta-galactosidase activity
ATHSA_RS09385	COG2723	6-phospho-beta-galactosidase activity
ATHSA_RS09390	COG3534	alpha-L-arabinofuranosidase
ATHSA_RS09395	COG1609	Transcriptional regulator
ATHSA_RS09400	COG4608	Belongs to the ABC transporter superfamily
ATHSA_RS09405	COG0444	Belongs to the ABC transporter superfamily
ATHSA_RS09410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_RS09425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATHSA_RS09430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATHSA_RS09445	COG0542	response to heat
ATHSA_RS09455	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ATHSA_RS09460	COG4956	integral membrane protein (PIN domain superfamily)
ATHSA_RS09465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATHSA_RS09470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATHSA_RS09495	COG0210	DNA helicase
ATHSA_RS09515	COG0736	holo-[acyl-carrier-protein] synthase activity
ATHSA_RS09530	COG3833	ABC-type maltose transport systems, permease component
ATHSA_RS09535	COG1175	transmembrane transport
ATHSA_RS09550	COG0366	Alpha amylase catalytic
ATHSA_RS09560	COG0300	oxidoreductase activity
ATHSA_RS09570	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ATHSA_RS09610	COG0195	Participates in both transcription termination and antitermination
ATHSA_RS09625	COG0174	glutamine synthetase
ATHSA_RS09655	COG0798	PFAM Bile acid sodium symporter
ATHSA_RS09660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATHSA_RS09675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATHSA_RS09685	COG1132	(ABC) transporter
ATHSA_RS09700	COG0776	regulation of translation
ATHSA_RS09705	COG1923	regulation of RNA biosynthetic process
ATHSA_RS09715	COG1396	sequence-specific DNA binding
ATHSA_RS09740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATHSA_RS09755	COG2199	diguanylate cyclase activity
ATHSA_RS09755	COG2203	Gaf domain
ATHSA_RS09760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ATHSA_RS09795	COG4974	Belongs to the 'phage' integrase family
ATHSA_RS09830	COG4166	transmembrane transport
ATHSA_RS09835	COG1940	carbohydrate kinase activity
ATHSA_RS09855	COG1192	Involved in chromosome partitioning
ATHSA_RS09875	COG1192	Involved in chromosome partitioning
ATHSA_RS09935	COG3328	transposase activity
ATHSA_RS09960	COG4974	Belongs to the 'phage' integrase family
ATHSA_RS09965	COG3328	transposase activity
ATHSA_RS09980	COG0426	domain, Protein
ATHSA_RS10005	COG3328	transposase activity
ATHSA_RS10010	COG3328	transposase activity
ATHSA_RS10015	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATHSA_RS10025	COG3328	transposase activity
ATHSA_RS10065	COG1923	regulation of RNA biosynthetic process
ATHSA_RS10070	COG0776	regulation of translation
ATHSA_RS10075	COG3189	MarR family transcriptional regulator