locus-tag	class	description
RT761_RS00005	COG0191	fructose-bisphosphate aldolase activity
RT761_RS00030	COG0395	ABC-type sugar transport system, permease component
RT761_RS00035	COG1175	transmembrane transport
RT761_RS00050	COG2186	Transcriptional regulator
RT761_RS00060	COG4948	Mandelate Racemase Muconate Lactonizing
RT761_RS00090	COG3290	protein histidine kinase activity
RT761_RS00095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RT761_RS00110	COG0395	ABC-type sugar transport system, permease component
RT761_RS00115	COG1175	transmembrane transport
RT761_RS00125	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS00160	COG0798	PFAM Bile acid sodium symporter
RT761_RS00180	COG3118	belongs to the thioredoxin family
RT761_RS00220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RT761_RS00225	COG0135	phosphoribosylanthranilate isomerase activity
RT761_RS00235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RT761_RS00245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RT761_RS00260	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RT761_RS00270	COG2226	methyltransferase
RT761_RS00295	COG0095	Lipoate-protein ligase
RT761_RS00300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RT761_RS00305	COG0508	dehydrogenase complex catalyzes the overall conversion of
RT761_RS00330	COG0758	DNA mediated transformation
RT761_RS00330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RT761_RS00335	COG0606	chelatase, subunit chli
RT761_RS00355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RT761_RS00360	COG0681	Belongs to the peptidase S26 family
RT761_RS00365	COG0335	large ribosomal subunit rRNA binding
RT761_RS00370	COG0336	Belongs to the RNA methyltransferase TrmD family
RT761_RS00375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RT761_RS00385	COG0228	four-way junction DNA binding
RT761_RS00390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RT761_RS00395	COG0552	protein localization to endoplasmic reticulum
RT761_RS00400	COG1196	nuclear chromosome segregation
RT761_RS00405	COG0571	ribonuclease III activity
RT761_RS00420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RT761_RS00425	COG2070	2-Nitropropane dioxygenase
RT761_RS00430	COG0416	fatty acid biosynthetic process
RT761_RS00435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RT761_RS00445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RT761_RS00450	COG0280	phosphate acetyltransferase
RT761_RS00455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RT761_RS00460	COG0742	ribosomal rna small subunit methyltransferase
RT761_RS00465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RT761_RS00470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RT761_RS00475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RT761_RS00485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RT761_RS00485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RT761_RS00490	COG2738	Putative neutral zinc metallopeptidase
RT761_RS00495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RT761_RS00500	COG0242	peptide deformylase activity
RT761_RS00505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RT761_RS00510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RT761_RS00520	COG0194	GDP metabolic process
RT761_RS00525	COG1561	YicC-like family, N-terminal region
RT761_RS00535	COG0564	pseudouridine synthase activity
RT761_RS00540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RT761_RS00545	COG3599	regulation of cell shape
RT761_RS00550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RT761_RS00555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RT761_RS00565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RT761_RS00575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RT761_RS00580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RT761_RS00585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RT761_RS00590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RT761_RS00595	COG0772	Belongs to the SEDS family
RT761_RS00600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RT761_RS00605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RT761_RS00610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RT761_RS00615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RT761_RS00630	COG0275	rRNA processing
RT761_RS00635	COG2001	Belongs to the MraZ family
RT761_RS00660	COG2172	sigma factor antagonist activity
RT761_RS00675	COG0525	valine-tRNA ligase activity
RT761_RS00680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RT761_RS00685	COG0740	serine-type endopeptidase activity
RT761_RS00690	COG0544	peptidyl-prolyl cis-trans isomerase activity
RT761_RS00700	COG1131	(ABC) transporter
RT761_RS00705	COG0640	Transcriptional regulator
RT761_RS00785	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_RS00790	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS00815	COG1234	tRNA 3'-trailer cleavage
RT761_RS00835	COG0445	tRNA wobble uridine modification
RT761_RS00845	COG0445	tRNA wobble uridine modification
RT761_RS00850	COG0395	ABC-type sugar transport system, permease component
RT761_RS00855	COG1175	transmembrane transport
RT761_RS00860	COG1609	Transcriptional regulator
RT761_RS00870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RT761_RS00875	COG0527	aspartate kinase activity
RT761_RS00880	COG0083	homoserine kinase activity
RT761_RS00885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RT761_RS00890	COG1959	2 iron, 2 sulfur cluster binding
RT761_RS00905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RT761_RS00910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RT761_RS00920	COG0067	glutamate synthase
RT761_RS00925	COG0174	glutamine synthetase
RT761_RS00940	COG0131	Imidazoleglycerol-phosphate dehydratase
RT761_RS00950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RT761_RS00960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RT761_RS00960	COG0140	phosphoribosyl-ATP diphosphatase activity
RT761_RS00970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RT761_RS00990	COG1129	ABC transporter
RT761_RS01005	COG0697	spore germination
RT761_RS01015	COG0436	Aminotransferase
RT761_RS01025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RT761_RS01030	COG0215	cysteine-tRNA ligase activity
RT761_RS01035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RT761_RS01040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RT761_RS01045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RT761_RS01050	COG4956	integral membrane protein (PIN domain superfamily)
RT761_RS01055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RT761_RS01060	COG0542	response to heat
RT761_RS01065	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RT761_RS01075	COG4463	regulation of RNA biosynthetic process
RT761_RS01080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RT761_RS01095	COG2223	nitrite transmembrane transporter activity
RT761_RS01100	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
RT761_RS01105	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS01110	COG1129	ABC transporter
RT761_RS01125	COG1175	transmembrane transport
RT761_RS01140	COG3415	Transposase
RT761_RS01140	COG2801	Transposase and inactivated derivatives
RT761_RS01205	COG3706	GGDEF domain
RT761_RS01210	COG0489	protein tyrosine kinase activity
RT761_RS01220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_RS01220	COG0731	radical SAM domain protein
RT761_RS01225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RT761_RS01265	COG0735	belongs to the Fur family
RT761_RS01275	COG0022	dehydrogenase e1 component
RT761_RS01280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_RS01285	COG0395	ABC-type sugar transport system, permease component
RT761_RS01290	COG1175	transmembrane transport
RT761_RS01300	COG0191	fructose-bisphosphate aldolase activity
RT761_RS01325	COG1253	flavin adenine dinucleotide binding
RT761_RS01335	COG2373	Large extracellular alpha-helical protein
RT761_RS01340	COG3234	Protein of unknown function (DUF1175)
RT761_RS01345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RT761_RS01350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RT761_RS01355	COG0167	dihydroorotate dehydrogenase activity
RT761_RS01360	COG0543	2 iron, 2 sulfur cluster binding
RT761_RS01365	COG0284	orotidine-5'-phosphate decarboxylase activity
RT761_RS01370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RT761_RS01375	COG0540	Belongs to the ATCase OTCase family
RT761_RS01380	COG1070	Carbohydrate kinase
RT761_RS01385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_RS01390	COG2140	Oxalate decarboxylase
RT761_RS01400	COG0673	inositol 2-dehydrogenase activity
RT761_RS01405	COG2188	Transcriptional regulator
RT761_RS01430	COG0395	ABC-type sugar transport system, permease component
RT761_RS01440	COG1653	transport
RT761_RS01445	COG1012	belongs to the aldehyde dehydrogenase family
RT761_RS01450	COG1070	Carbohydrate kinase
RT761_RS01470	COG0277	FAD linked oxidase domain protein
RT761_RS01480	COG1070	Carbohydrate kinase
RT761_RS01490	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS01495	COG1129	ABC transporter
RT761_RS01510	COG0800	Aldolase
RT761_RS01515	COG1525	nuclease
RT761_RS01520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RT761_RS01530	COG1704	LemA family
RT761_RS01545	COG0697	spore germination
RT761_RS01550	COG0222	ribosome binding
RT761_RS01555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RT761_RS01560	COG0081	regulation of translation
RT761_RS01565	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RT761_RS01570	COG0250	Participates in transcription elongation, termination and antitermination
RT761_RS01575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RT761_RS01585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RT761_RS01590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RT761_RS01610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_RS01610	COG3153	acetyltransferase
RT761_RS01640	COG1070	Carbohydrate kinase
RT761_RS01645	COG1245	4Fe-4S binding domain
RT761_RS01645	COG2878	Part of a membrane complex involved in electron transport
RT761_RS01650	COG4657	Part of a membrane complex involved in electron transport
RT761_RS01655	COG4660	Part of a membrane complex involved in electron transport
RT761_RS01660	COG4659	FMN binding
RT761_RS01665	COG4658	electron transport chain
RT761_RS01670	COG4656	Part of a membrane complex involved in electron transport
RT761_RS01675	COG0439	Biotin carboxylase
RT761_RS01680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RT761_RS01685	COG0330	HflC and HflK could
RT761_RS01690	COG0330	HflC and HflK could
RT761_RS01705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RT761_RS01720	COG1063	alcohol dehydrogenase
RT761_RS01730	COG0693	protein deglycase activity
RT761_RS01745	COG1132	(ABC) transporter
RT761_RS01750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_RS01755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_RS01765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_RS01770	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RT761_RS01775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_RS01785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RT761_RS01800	COG1077	Cell shape determining protein MreB Mrl
RT761_RS01805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RT761_RS01835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_RS01840	COG4481	Protein conserved in bacteria
RT761_RS01845	COG0778	Nitroreductase
RT761_RS01870	COG1454	alcohol dehydrogenase
RT761_RS01880	COG0667	Aldo Keto reductase
RT761_RS01885	COG0019	diaminopimelate decarboxylase activity
RT761_RS01895	COG1079	Belongs to the binding-protein-dependent transport system permease family
RT761_RS01905	COG3845	ABC transporter
RT761_RS01910	COG0473	3-isopropylmalate dehydrogenase activity
RT761_RS01915	COG0179	Fumarylacetoacetate (FAA) hydrolase
RT761_RS01925	COG4372	Transposase
RT761_RS01935	COG1137	ATPase activity
RT761_RS01965	COG0463	Glycosyl transferase, family 2
RT761_RS01970	COG0628	permease
RT761_RS01975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RT761_RS02000	COG1595	DNA-templated transcription, initiation
RT761_RS02010	COG1045	serine acetyltransferase
RT761_RS02025	COG1609	Transcriptional regulator
RT761_RS02045	COG1609	Transcriptional regulator
RT761_RS02050	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS02055	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS02060	COG1129	ABC transporter
RT761_RS02075	COG5609	conserved protein (DUF2294)
RT761_RS02090	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS02105	COG2264	protein methyltransferase activity
RT761_RS02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RT761_RS02115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RT761_RS02150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT761_RS02155	COG0493	'glutamate synthase
RT761_RS02155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RT761_RS02170	COG0756	dUTP diphosphatase activity
RT761_RS02175	COG0058	SHG alpha-glucan phosphorylase activity
RT761_RS02195	COG0017	Asparaginyl-tRNA synthetase
RT761_RS02210	COG0559	Belongs to the binding-protein-dependent transport system permease family
RT761_RS02240	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_RS02255	COG1098	S1 RNA binding domain
RT761_RS02265	COG0148	phosphopyruvate hydratase activity
RT761_RS02270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RT761_RS02280	COG3956	TIGRFAM MazG family protein
RT761_RS02285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RT761_RS02295	COG0193	aminoacyl-tRNA hydrolase activity
RT761_RS02300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RT761_RS02310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RT761_RS02320	COG2848	UPF0210 protein
RT761_RS02325	COG3830	Belongs to the UPF0237 family
RT761_RS02330	COG1515	deoxyribonuclease V activity
RT761_RS02340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RT761_RS02360	COG0084	hydrolase, TatD family'
RT761_RS02365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_RS02365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_RS02370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_RS02370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_RS02375	COG0534	Mate efflux family protein
RT761_RS02395	COG2801	Transposase and inactivated derivatives
RT761_RS02395	COG3415	Transposase
RT761_RS02415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RT761_RS02420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RT761_RS02430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RT761_RS02445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RT761_RS02550	COG0438	transferase activity, transferring glycosyl groups
RT761_RS02555	COG3307	-O-antigen
RT761_RS02565	COG0463	Glycosyl transferase, family 2
RT761_RS02565	COG1216	Glycosyl transferase, family 2
RT761_RS02585	COG1132	(ABC) transporter
RT761_RS02590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RT761_RS02640	COG3415	Transposase
RT761_RS02640	COG2801	Transposase and inactivated derivatives
RT761_RS02665	COG0667	Aldo Keto reductase
RT761_RS02690	COG1528	Iron-storage protein
RT761_RS02695	COG0426	domain, Protein
RT761_RS02700	COG3706	GGDEF domain
RT761_RS02715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RT761_RS02725	COG2861	carbohydrate metabolic process
RT761_RS02730	COG0793	Belongs to the peptidase S41A family
RT761_RS02745	COG2884	Cell division ATP-binding protein ftsE
RT761_RS02765	COG0511	ligase activity, forming carbon-carbon bonds
RT761_RS02780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RT761_RS02790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RT761_RS02795	COG0653	protein targeting
RT761_RS02805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_RS02820	COG1105	Belongs to the carbohydrate kinase PfkB family
RT761_RS02825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS02830	COG1070	Carbohydrate kinase
RT761_RS02835	COG0508	dehydrogenase complex catalyzes the overall conversion of
RT761_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS02855	COG1070	Carbohydrate kinase
RT761_RS02860	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS02865	COG1070	Carbohydrate kinase
RT761_RS02875	COG0022	dehydrogenase e1 component
RT761_RS02885	COG1063	alcohol dehydrogenase
RT761_RS02895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS02900	COG2390	Transcriptional regulator
RT761_RS02905	COG1040	competence protein
RT761_RS02935	COG2176	DNA-directed DNA polymerase activity
RT761_RS02935	COG5002	protein histidine kinase activity
RT761_RS02965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RT761_RS02980	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS02985	COG1129	ABC transporter
RT761_RS02995	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS03005	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS03015	COG1129	ABC transporter
RT761_RS03020	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RT761_RS03035	COG1063	alcohol dehydrogenase
RT761_RS03040	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03045	COG4603	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03050	COG1129	ABC transporter
RT761_RS03055	COG1609	Transcriptional regulator
RT761_RS03060	COG1063	alcohol dehydrogenase
RT761_RS03065	COG4869	propanediol catabolic process
RT761_RS03070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RT761_RS03075	COG0698	ribose 5-phosphate isomerase
RT761_RS03085	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_RS03090	COG1012	belongs to the aldehyde dehydrogenase family
RT761_RS03105	COG4656	Part of a membrane complex involved in electron transport
RT761_RS03110	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_RS03115	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_RS03120	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RT761_RS03125	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RT761_RS03135	COG1070	Carbohydrate kinase
RT761_RS03145	COG4214	carbohydrate transport
RT761_RS03150	COG1129	ABC transporter
RT761_RS03155	COG4213	ABC transporter substrate-binding protein
RT761_RS03195	COG1228	amidohydrolase
RT761_RS03200	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03205	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03210	COG1129	ABC transporter
RT761_RS03220	COG1349	DNA-binding transcription factor activity
RT761_RS03225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RT761_RS03230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RT761_RS03245	COG0698	ribose 5-phosphate isomerase
RT761_RS03250	COG1461	Dihydroxyacetone kinase
RT761_RS03255	COG2376	Dihydroxyacetone kinase
RT761_RS03260	COG1070	Carbohydrate kinase
RT761_RS03265	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS03270	COG3842	ATPase activity
RT761_RS03275	COG3842	ATPase activity
RT761_RS03285	COG0395	ABC-type sugar transport system, permease component
RT761_RS03290	COG1175	transmembrane transport
RT761_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS03325	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS03330	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS03335	COG1063	alcohol dehydrogenase
RT761_RS03355	COG0022	dehydrogenase e1 component
RT761_RS03360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_RS03370	COG0644	oxidoreductase
RT761_RS03385	COG1609	Transcriptional regulator
RT761_RS03390	COG1063	alcohol dehydrogenase
RT761_RS03415	COG0395	ABC-type sugar transport system, permease component
RT761_RS03420	COG1175	transmembrane transport
RT761_RS03425	COG1653	transport
RT761_RS03440	COG0129	dihydroxy-acid dehydratase activity
RT761_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS03455	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03460	COG1129	ABC transporter
RT761_RS03470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_RS03480	COG3971	2-oxopent-4-enoate hydratase activity
RT761_RS03485	COG2197	response regulator
RT761_RS03505	COG0450	alkyl hydroperoxide reductase
RT761_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS03545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RT761_RS03555	COG0446	pyridine nucleotide-disulphide oxidoreductase
RT761_RS03565	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS03570	COG1129	ABC transporter
RT761_RS03575	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS03605	COG1129	ABC transporter
RT761_RS03620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RT761_RS03620	COG5322	oxidoreductase activity
RT761_RS03645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RT761_RS03650	COG3415	Transposase
RT761_RS03650	COG2801	Transposase and inactivated derivatives
RT761_RS03660	COG3191	aminopeptidase activity
RT761_RS03675	COG0459	protein refolding
RT761_RS03680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RT761_RS03715	COG1609	Transcriptional regulator
RT761_RS03730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RT761_RS03735	COG1136	(ABC) transporter
RT761_RS03735	COG0577	efflux transmembrane transporter activity
RT761_RS03745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RT761_RS03755	COG1104	cysteine desulfurase activity
RT761_RS03780	COG0671	phosphoesterase, PA-phosphatase related
RT761_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RT761_RS03800	COG0129	dihydroxy-acid dehydratase activity
RT761_RS03805	COG0028	Belongs to the TPP enzyme family
RT761_RS03810	COG0440	acetolactate synthase activity
RT761_RS03815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RT761_RS03820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_RS03825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RT761_RS03830	COG0066	3-isopropylmalate dehydratase activity
RT761_RS03840	COG1609	Transcriptional regulator
RT761_RS03845	COG2264	protein methyltransferase activity
RT761_RS03855	COG1191	sigma factor activity
RT761_RS03870	COG0473	3-isopropylmalate dehydrogenase activity
RT761_RS03885	COG1595	DNA-templated transcription, initiation
RT761_RS03905	COG2059	Chromate
RT761_RS03910	COG2059	Chromate
RT761_RS03915	COG1739	Uncharacterized protein family UPF0029
RT761_RS03920	COG3850	Histidine kinase
RT761_RS03920	COG5002	protein histidine kinase activity
RT761_RS03925	COG0745	RESPONSE REGULATOR receiver
RT761_RS03940	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RT761_RS03940	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RT761_RS03980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RT761_RS03985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RT761_RS03990	COG0187	DNA topoisomerase II activity
RT761_RS04000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RT761_RS04005	COG0592	DNA-directed DNA polymerase activity
RT761_RS04010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RT761_RS04015	COG0395	ABC-type sugar transport system, permease component
RT761_RS04035	COG1940	carbohydrate kinase activity
RT761_RS04040	COG0022	dehydrogenase e1 component
RT761_RS04045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_RS04065	COG2084	Dehydrogenase
RT761_RS04080	COG0167	dihydroorotate dehydrogenase activity
RT761_RS04085	COG0674	pyruvate-flavodoxin oxidoreductase activity
RT761_RS04085	COG1013	pyruvate-flavodoxin oxidoreductase activity
RT761_RS04085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RT761_RS04085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RT761_RS04090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RT761_RS04095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RT761_RS04100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RT761_RS04120	COG1940	carbohydrate kinase activity
RT761_RS04125	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RT761_RS04135	COG1175	transmembrane transport
RT761_RS04150	COG1151	hydroxylamine reductase activity
RT761_RS04185	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS04190	COG1129	ABC transporter
RT761_RS04195	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS04230	COG3328	transposase activity
RT761_RS04250	COG0277	FAD linked oxidase domain protein
RT761_RS04255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RT761_RS04260	COG2086	electron transfer activity
RT761_RS04265	COG0395	ABC-type sugar transport system, permease component
RT761_RS04270	COG1175	transmembrane transport
RT761_RS04280	COG1830	Aldolase
RT761_RS04285	COG1063	alcohol dehydrogenase
RT761_RS04290	COG1070	Carbohydrate kinase
RT761_RS04325	COG3459	Glycosyltransferase 36 associated
RT761_RS04340	COG0432	Pfam Uncharacterised protein family UPF0047
RT761_RS04370	COG0436	Aminotransferase
RT761_RS04375	COG0004	ammonium transporteR
RT761_RS04380	COG0347	Belongs to the P(II) protein family
RT761_RS04390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RT761_RS04395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RT761_RS04405	COG0860	N-Acetylmuramoyl-L-alanine amidase
RT761_RS04410	COG0629	single-stranded DNA binding
RT761_RS04415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_RS04430	COG0157	Belongs to the NadC ModD family
RT761_RS04435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RT761_RS04455	COG4608	Belongs to the ABC transporter superfamily
RT761_RS04460	COG0444	Belongs to the ABC transporter superfamily
RT761_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_RS04470	COG0601	transmembrane transport
RT761_RS04475	COG0747	negative chemotaxis
RT761_RS04505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RT761_RS04530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RT761_RS04555	COG0497	DNA recombination
RT761_RS04580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RT761_RS04600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT761_RS04605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RT761_RS04650	COG4608	Belongs to the ABC transporter superfamily
RT761_RS04665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RT761_RS04675	COG1722	exodeoxyribonuclease VII activity
RT761_RS04680	COG1570	exodeoxyribonuclease VII activity
RT761_RS04685	COG1164	Oligoendopeptidase f
RT761_RS04715	COG4717	serine-type aminopeptidase activity
RT761_RS04740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_RS04745	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_RS04750	COG2770	Histidine kinase
RT761_RS04750	COG2205	protein histidine kinase activity
RT761_RS04755	COG0745	RESPONSE REGULATOR receiver
RT761_RS04770	COG0577	efflux transmembrane transporter activity
RT761_RS04770	COG1136	(ABC) transporter
RT761_RS04795	COG2801	Transposase and inactivated derivatives
RT761_RS04795	COG3415	Transposase
RT761_RS04810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RT761_RS04815	COG0482	sulfurtransferase activity
RT761_RS04820	COG0037	tRNA processing
RT761_RS04835	COG2003	Belongs to the UPF0758 family
RT761_RS04845	COG1177	transmembrane transport
RT761_RS04855	COG3842	ATPase activity
RT761_RS04870	COG5598	trimethylamine methyltransferase
RT761_RS04875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_RS04880	COG0656	L-ascorbic acid biosynthetic process
RT761_RS04885	COG2608	mercury ion transmembrane transporter activity
RT761_RS04890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_RS04910	COG0367	asparagine synthase
RT761_RS04915	COG2801	Transposase and inactivated derivatives
RT761_RS04915	COG3415	Transposase
RT761_RS04920	COG0598	Magnesium transport protein CorA
RT761_RS04925	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_RS04930	COG0667	Aldo Keto reductase
RT761_RS04940	COG1940	carbohydrate kinase activity
RT761_RS04945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RT761_RS04950	COG1070	Carbohydrate kinase
RT761_RS04955	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RT761_RS04970	COG0706	membrane insertase activity
RT761_RS04975	COG1847	R3H domain protein
RT761_RS04985	COG0357	Ribosomal RNA small subunit methyltransferase G
RT761_RS04990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RT761_RS04995	COG1192	Involved in chromosome partitioning
RT761_RS05000	COG1475	DNA binding
RT761_RS05005	COG0739	heme binding
RT761_RS05020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS05030	COG1881	PFAM PEBP family protein
RT761_RS05050	COG1230	cation diffusion facilitator family transporter
RT761_RS05060	COG1592	Rubrerythrin
RT761_RS05085	COG1175	transmembrane transport
RT761_RS05090	COG0395	ABC-type sugar transport system, permease component
RT761_RS05095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RT761_RS05115	COG4974	Belongs to the 'phage' integrase family
RT761_RS05190	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS05215	COG1609	Transcriptional regulator
RT761_RS05220	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS05255	COG4584	PFAM Integrase catalytic
RT761_RS05260	COG1484	DNA-dependent DNA replication
RT761_RS05315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RT761_RS05335	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS05350	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_RS05380	COG1175	transmembrane transport
RT761_RS05415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS05420	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS05440	COG4584	PFAM Integrase catalytic
RT761_RS05445	COG1484	DNA-dependent DNA replication
RT761_RS05455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RT761_RS05530	COG1929	Belongs to the glycerate kinase type-1 family
RT761_RS05535	COG0497	DNA recombination
RT761_RS05545	COG2801	Transposase and inactivated derivatives
RT761_RS05545	COG3415	Transposase
RT761_RS05565	COG0668	transmembrane transport
RT761_RS05570	COG2222	sugar isomerase
RT761_RS05575	COG0737	Belongs to the 5'-nucleotidase family
RT761_RS05615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RT761_RS05625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RT761_RS05655	COG1063	alcohol dehydrogenase
RT761_RS05665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RT761_RS05675	COG0803	Belongs to the bacterial solute-binding protein 9 family
RT761_RS05680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT761_RS05690	COG1175	transmembrane transport
RT761_RS05710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RT761_RS05715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RT761_RS05720	COG0509	glycine decarboxylation via glycine cleavage system
RT761_RS05725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RT761_RS05730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RT761_RS05735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RT761_RS05740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RT761_RS05755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RT761_RS05760	COG0673	inositol 2-dehydrogenase activity
RT761_RS05775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RT761_RS05795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RT761_RS05810	COG1175	transmembrane transport
RT761_RS05820	COG3842	ATPase activity
RT761_RS05825	COG3842	ATPase activity
RT761_RS05830	COG1063	alcohol dehydrogenase
RT761_RS05835	COG3344	reverse transcriptase
RT761_RS05855	COG1070	Carbohydrate kinase
RT761_RS05860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RT761_RS05870	COG1105	Belongs to the carbohydrate kinase PfkB family
RT761_RS05875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RT761_RS05885	COG1472	Belongs to the glycosyl hydrolase 3 family
RT761_RS05890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RT761_RS05895	COG1970	mechanosensitive ion channel activity
RT761_RS05905	COG4659	FMN binding
RT761_RS05915	COG2816	NAD+ diphosphatase activity
RT761_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS05930	COG1129	ABC transporter
RT761_RS05935	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS05940	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS05955	COG2246	polysaccharide biosynthetic process
RT761_RS05960	COG0463	Glycosyl transferase, family 2
RT761_RS05980	COG1609	Transcriptional regulator
RT761_RS06065	COG0166	Belongs to the GPI family
RT761_RS06070	COG0697	spore germination
RT761_RS06075	COG0300	oxidoreductase activity
RT761_RS06080	COG1063	alcohol dehydrogenase
RT761_RS06100	COG1175	transmembrane transport
RT761_RS06125	COG0673	inositol 2-dehydrogenase activity
RT761_RS06130	COG1129	ABC transporter
RT761_RS06135	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06145	COG0588	phosphoglycerate mutase activity
RT761_RS06170	COG0006	proline dipeptidase activity
RT761_RS06180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_RS06185	COG1940	carbohydrate kinase activity
RT761_RS06195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_RS06200	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS06210	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_RS06275	COG2033	superoxide reductase activity
RT761_RS06280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_RS06285	COG0205	6-phosphofructokinase activity
RT761_RS06305	COG0235	Class ii aldolase
RT761_RS06310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RT761_RS06315	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RT761_RS06350	COG1175	transmembrane transport
RT761_RS06355	COG0395	ABC-type sugar transport system, permease component
RT761_RS06360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RT761_RS06365	COG0681	Belongs to the peptidase S26 family
RT761_RS06370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RT761_RS06385	COG0191	fructose-bisphosphate aldolase activity
RT761_RS06390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_RS06400	COG2801	Transposase and inactivated derivatives
RT761_RS06400	COG3415	Transposase
RT761_RS06435	COG1126	abc transporter atp-binding protein
RT761_RS06440	COG0765	amino acid transport
RT761_RS06445	COG3876	Protein conserved in bacteria
RT761_RS06450	COG1971	Probably functions as a manganese efflux pump
RT761_RS06455	COG0731	radical SAM domain protein
RT761_RS06455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_RS06460	COG1194	a g-specific adenine glycosylase
RT761_RS06470	COG0646	methionine synthase
RT761_RS06470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RT761_RS06490	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06500	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06535	COG0318	PFAM AMP-dependent synthetase and ligase
RT761_RS06540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RT761_RS06545	COG0436	Aminotransferase
RT761_RS06550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RT761_RS06555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RT761_RS06570	COG0205	6-phosphofructokinase activity
RT761_RS06575	COG0483	inositol monophosphate 1-phosphatase activity
RT761_RS06590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_RS06605	COG1129	ABC transporter
RT761_RS06610	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06615	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS06635	COG2852	Protein conserved in bacteria
RT761_RS06650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_RS06650	COG2199	diguanylate cyclase activity
RT761_RS06655	COG2226	methyltransferase
RT761_RS06660	COG0735	belongs to the Fur family
RT761_RS06665	COG0753	catalase activity
RT761_RS06670	COG2832	Protein of unknown function (DUF454)
RT761_RS06705	COG1175	transmembrane transport
RT761_RS06710	COG0395	ABC-type sugar transport system, permease component
RT761_RS06745	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_RS06800	COG1175	transmembrane transport
RT761_RS06805	COG0395	ABC-type sugar transport system, permease component
RT761_RS06810	COG1175	transmembrane transport
RT761_RS06815	COG0395	ABC-type sugar transport system, permease component
RT761_RS06820	COG1653	transport
RT761_RS06825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RT761_RS06855	COG0738	Major facilitator superfamily
RT761_RS06890	COG1764	response to oxidative stress
RT761_RS06905	COG3415	Transposase
RT761_RS06905	COG2801	Transposase and inactivated derivatives
RT761_RS06925	COG2239	Acts as a magnesium transporter
RT761_RS06950	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS07030	COG4584	PFAM Integrase catalytic
RT761_RS07035	COG1484	DNA-dependent DNA replication
RT761_RS07075	COG4974	Belongs to the 'phage' integrase family
RT761_RS07105	COG0006	proline dipeptidase activity
RT761_RS07115	COG1129	ABC transporter
RT761_RS07120	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07145	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07160	COG1940	carbohydrate kinase activity
RT761_RS07165	COG0673	inositol 2-dehydrogenase activity
RT761_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS07180	COG1175	transmembrane transport
RT761_RS07185	COG0395	ABC-type sugar transport system, permease component
RT761_RS07200	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS07205	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07215	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS07220	COG1129	ABC transporter
RT761_RS07225	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07235	COG1979	alcohol dehydrogenase
RT761_RS07240	COG1773	rubredoxin
RT761_RS07240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RT761_RS07255	COG4585	Histidine kinase
RT761_RS07260	COG2197	response regulator
RT761_RS07265	COG0546	phosphoglycolate phosphatase activity
RT761_RS07300	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS07340	COG0019	diaminopimelate decarboxylase activity
RT761_RS07350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RT761_RS07355	COG0436	Aminotransferase
RT761_RS07360	COG0527	aspartate kinase activity
RT761_RS07365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RT761_RS07370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RT761_RS07375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RT761_RS07380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RT761_RS07385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RT761_RS07390	COG0137	argininosuccinate synthase activity
RT761_RS07395	COG0165	Argininosuccinate lyase
RT761_RS07400	COG0174	glutamine synthetase
RT761_RS07405	COG0445	tRNA wobble uridine modification
RT761_RS07410	COG1446	asparaginase
RT761_RS07435	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RT761_RS07440	COG0352	thiamine-phosphate diphosphorylase activity
RT761_RS07445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RT761_RS07450	COG0352	thiamine-phosphate diphosphorylase activity
RT761_RS07450	COG0351	phosphomethylpyrimidine kinase
RT761_RS07455	COG0667	Aldo Keto reductase
RT761_RS07460	COG3415	Transposase
RT761_RS07460	COG2801	Transposase and inactivated derivatives
RT761_RS07475	COG2720	vancomycin resistance protein
RT761_RS07480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RT761_RS07485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RT761_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RT761_RS07495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RT761_RS07500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RT761_RS07505	COG3118	belongs to the thioredoxin family
RT761_RS07520	COG1129	ABC transporter
RT761_RS07525	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07550	COG1067	ATP-dependent peptidase activity
RT761_RS07560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RT761_RS07565	COG0443	Heat shock 70 kDa protein
RT761_RS07570	COG0484	heat shock protein binding
RT761_RS07575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RT761_RS07580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_RS07595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT761_RS07600	COG0371	Dehydrogenase
RT761_RS07610	COG1032	radical SAM domain protein
RT761_RS07620	COG0505	Belongs to the CarA family
RT761_RS07625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RT761_RS07640	COG1013	pyruvate-flavodoxin oxidoreductase activity
RT761_RS07655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RT761_RS07665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RT761_RS07670	COG0151	Belongs to the GarS family
RT761_RS07675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RT761_RS07680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RT761_RS07685	COG1573	uracil-dna glycosylase
RT761_RS07700	COG3854	ATPases associated with a variety of cellular activities
RT761_RS07705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RT761_RS07710	COG3870	Protein conserved in bacteria
RT761_RS07720	COG1774	PSP1 C-terminal conserved region
RT761_RS07745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RT761_RS07750	COG0573	inorganic phosphate transmembrane transporter activity
RT761_RS07755	COG0581	inorganic phosphate transmembrane transporter activity
RT761_RS07760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RT761_RS07770	COG0811	peptide transport
RT761_RS07775	COG0848	biopolymer transport protein
RT761_RS07780	COG1470	cell adhesion involved in biofilm formation
RT761_RS07790	COG4974	Belongs to the 'phage' integrase family
RT761_RS07795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RT761_RS07805	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RT761_RS07820	COG1070	Carbohydrate kinase
RT761_RS07830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RT761_RS07840	COG4120	Belongs to the binding-protein-dependent transport system permease family
RT761_RS07845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RT761_RS07850	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RT761_RS07860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RT761_RS07865	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RT761_RS07900	COG0495	leucyl-tRNA aminoacylation
RT761_RS07910	COG1302	Protein conserved in bacteria
RT761_RS07915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RT761_RS07925	COG1702	phosphate starvation-inducible protein PhoH
RT761_RS07930	COG1480	7TM receptor with intracellular HD hydrolase
RT761_RS07935	COG0295	cytidine deaminase activity
RT761_RS07940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RT761_RS07945	COG1381	Involved in DNA repair and RecF pathway recombination
RT761_RS07950	COG0752	glycyl-tRNA synthetase alpha subunit
RT761_RS07955	COG0751	glycine-tRNA ligase activity
RT761_RS07960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RT761_RS07965	COG0574	Belongs to the PEP-utilizing enzyme family
RT761_RS07965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RT761_RS07970	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RT761_RS07975	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RT761_RS07980	COG0358	DNA primase activity
RT761_RS07985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RT761_RS08010	COG3437	response regulator, receiver
RT761_RS08040	COG3706	GGDEF domain
RT761_RS08055	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_RS08095	COG0395	ABC-type sugar transport system, permease component
RT761_RS08100	COG1175	transmembrane transport
RT761_RS08115	COG1609	Transcriptional regulator
RT761_RS08135	COG1522	sequence-specific DNA binding
RT761_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS08160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RT761_RS08175	COG1720	tRNA m6t6A37 methyltransferase activity
RT761_RS08225	COG1484	DNA-dependent DNA replication
RT761_RS08230	COG4584	PFAM Integrase catalytic
RT761_RS08240	COG0395	ABC-type sugar transport system, permease component
RT761_RS08255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RT761_RS08270	COG1125	glycine betaine transport
RT761_RS08270	COG0517	IMP dehydrogenase activity
RT761_RS08275	COG1732	Glycine betaine
RT761_RS08290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RT761_RS08300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT761_RS08310	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RT761_RS08315	COG2183	response to ionizing radiation
RT761_RS08325	COG1278	Cold shock
RT761_RS08335	COG0488	(ABC) transporter
RT761_RS08345	COG0318	PFAM AMP-dependent synthetase and ligase
RT761_RS08350	COG0039	L-malate dehydrogenase activity
RT761_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS08400	COG0012	GTP binding
RT761_RS08410	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RT761_RS08475	COG1074	ATP-dependent DNA helicase activity
RT761_RS08480	COG0395	ABC-type sugar transport system, permease component
RT761_RS08485	COG1175	transmembrane transport
RT761_RS08495	COG1129	ABC transporter
RT761_RS08505	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS08510	COG1070	Carbohydrate kinase
RT761_RS08515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RT761_RS08520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RT761_RS08530	COG0438	transferase activity, transferring glycosyl groups
RT761_RS08555	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS08560	COG2186	Transcriptional regulator
RT761_RS08565	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS08580	COG2086	electron transfer activity
RT761_RS08585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RT761_RS08590	COG0277	FAD linked oxidase domain protein
RT761_RS08595	COG1132	(ABC) transporter
RT761_RS08600	COG1132	(ABC) transporter
RT761_RS08610	COG0133	tryptophan synthase activity
RT761_RS08615	COG0159	tryptophan synthase activity
RT761_RS08625	COG1129	ABC transporter
RT761_RS08630	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS08635	COG1070	Carbohydrate kinase
RT761_RS08645	COG3548	integral membrane protein
RT761_RS08665	COG2059	Chromate
RT761_RS08675	COG0395	ABC-type sugar transport system, permease component
RT761_RS08690	COG5598	trimethylamine methyltransferase
RT761_RS08695	COG3622	Belongs to the hyi family
RT761_RS08700	COG1940	carbohydrate kinase activity
RT761_RS08705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_RS08725	COG1129	ABC transporter
RT761_RS08730	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS08735	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS08770	COG1136	(ABC) transporter
RT761_RS08780	COG1215	transferase activity, transferring glycosyl groups
RT761_RS08805	COG2342	PFAM TM1410 hypothetical-related protein
RT761_RS08815	COG1030	water channel activity
RT761_RS08820	COG4864	UPF0365 protein
RT761_RS08830	COG0395	ABC-type sugar transport system, permease component
RT761_RS08835	COG1175	transmembrane transport
RT761_RS08845	COG0246	Mannitol dehydrogenase
RT761_RS08860	COG0346	lactoylglutathione lyase activity
RT761_RS08875	COG0384	phenazine biosynthesis protein PhzF
RT761_RS08910	COG1609	Transcriptional regulator
RT761_RS08915	COG0006	proline dipeptidase activity
RT761_RS08925	COG1175	transmembrane transport
RT761_RS08930	COG0395	ABC-type sugar transport system, permease component
RT761_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS08960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RT761_RS08975	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RT761_RS08990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RT761_RS09020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RT761_RS09060	COG0641	radical SAM
RT761_RS09065	COG3119	arylsulfatase activity
RT761_RS09095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RT761_RS09100	COG0732	type I restriction modification DNA specificity domain
RT761_RS09130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
RT761_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS09185	COG1337	RAMP superfamily
RT761_RS09195	COG1353	crispr-associated protein
RT761_RS09225	COG1484	DNA-dependent DNA replication
RT761_RS09230	COG4584	PFAM Integrase catalytic
RT761_RS09245	COG1518	maintenance of DNA repeat elements
RT761_RS09250	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
RT761_RS09255	COG4584	PFAM Integrase catalytic
RT761_RS09260	COG1484	DNA-dependent DNA replication
RT761_RS09345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RT761_RS09345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RT761_RS09355	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS09360	COG1129	ABC transporter
RT761_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_RS09370	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS09415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_RS09420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_RS09420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RT761_RS09440	COG0095	Lipoate-protein ligase
RT761_RS09450	COG3447	MASE1 domain protein
RT761_RS09450	COG5001	Diguanylate cyclase
RT761_RS09450	COG5002	protein histidine kinase activity
RT761_RS09475	COG2135	peptidase activity
RT761_RS09510	COG1175	transmembrane transport
RT761_RS09515	COG0395	ABC-type sugar transport system, permease component
RT761_RS09520	COG1609	Transcriptional regulator
RT761_RS09525	COG0006	proline dipeptidase activity
RT761_RS09530	COG0395	ABC-type sugar transport system, permease component
RT761_RS09540	COG0438	transferase activity, transferring glycosyl groups
RT761_RS09560	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_RS09560	COG2199	diguanylate cyclase activity
RT761_RS09565	COG1472	Belongs to the glycosyl hydrolase 3 family
RT761_RS09570	COG4608	Belongs to the ABC transporter superfamily
RT761_RS09575	COG0444	Belongs to the ABC transporter superfamily
RT761_RS09585	COG0601	transmembrane transport
RT761_RS09595	COG1609	Transcriptional regulator
RT761_RS09600	COG4690	dipeptidase activity
RT761_RS09620	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS09625	COG1129	ABC transporter
RT761_RS09635	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS09640	COG1129	ABC transporter
RT761_RS09670	COG1454	alcohol dehydrogenase
RT761_RS09690	COG0217	transcriptional regulatory protein
RT761_RS09695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RT761_RS09700	COG0632	four-way junction helicase activity
RT761_RS09705	COG2255	four-way junction helicase activity
RT761_RS09710	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RT761_RS09720	COG2385	sporulation resulting in formation of a cellular spore
RT761_RS09725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RT761_RS09730	COG0343	queuine tRNA-ribosyltransferase activity
RT761_RS09735	COG1862	Preprotein translocase
RT761_RS09740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT761_RS09745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT761_RS09750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RT761_RS09750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RT761_RS09755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RT761_RS09760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RT761_RS09765	COG1490	D-aminoacyl-tRNA deacylase activity
RT761_RS09775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RT761_RS09780	COG3707	response regulator
RT761_RS09785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RT761_RS09790	COG1121	(ABC) transporter
RT761_RS09830	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS09835	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS09840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RT761_RS09850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RT761_RS09855	COG0785	Cytochrome C biogenesis protein
RT761_RS09885	COG0704	Plays a role in the regulation of phosphate uptake
RT761_RS09900	COG1063	alcohol dehydrogenase
RT761_RS09905	COG1063	alcohol dehydrogenase
RT761_RS09910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RT761_RS09925	COG0037	tRNA processing
RT761_RS09935	COG0037	tRNA processing
RT761_RS09940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RT761_RS09945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RT761_RS09955	COG0569	domain protein
RT761_RS09970	COG2359	stage V sporulation protein S
RT761_RS09980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_RS10000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_RS10000	COG2199	diguanylate cyclase activity
RT761_RS10030	COG1879	ABC-type sugar transport system periplasmic component
RT761_RS10040	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS10045	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS10050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RT761_RS10065	COG0110	maltose O-acetyltransferase activity
RT761_RS10075	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RT761_RS10085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RT761_RS10090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RT761_RS10095	COG0124	histidyl-tRNA synthetase
RT761_RS10110	COG2321	neutral zinc metallopeptidase
RT761_RS10120	COG2390	Transcriptional regulator
RT761_RS10125	COG1653	transport
RT761_RS10165	COG1063	alcohol dehydrogenase
RT761_RS10185	COG0534	Mate efflux family protein
RT761_RS10190	COG1331	Highly conserved protein containing a thioredoxin domain
RT761_RS10195	COG0028	Belongs to the TPP enzyme family
RT761_RS10200	COG0747	negative chemotaxis
RT761_RS10210	COG1121	(ABC) transporter
RT761_RS10215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT761_RS10220	COG4822	anaerobic cobalamin biosynthetic process
RT761_RS10245	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RT761_RS10255	COG1797	cobyrinic acid a,c-diamide synthase activity
RT761_RS10265	COG0018	arginyl-trna synthetase
RT761_RS10270	COG0504	CTP synthase activity
RT761_RS10280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RT761_RS10290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RT761_RS10295	COG0254	rRNA binding
RT761_RS10300	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
RT761_RS10305	COG3872	metal-dependent enzyme
RT761_RS10310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RT761_RS10320	COG0698	ribose 5-phosphate isomerase
RT761_RS10330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RT761_RS10335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RT761_RS10340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RT761_RS10345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RT761_RS10350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RT761_RS10365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RT761_RS10375	COG0356	it plays a direct role in the translocation of protons across the membrane
RT761_RS10455	COG3328	transposase activity
RT761_RS10465	COG3264	Mechanosensitive ion channel
RT761_RS10465	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RT761_RS10485	COG0667	Aldo Keto reductase
RT761_RS10495	COG0395	ABC-type sugar transport system, permease component
RT761_RS10510	COG4821	SIS domain
RT761_RS10515	COG2188	Transcriptional regulator
RT761_RS10520	COG4821	SIS domain
RT761_RS10525	COG1070	Carbohydrate kinase
RT761_RS10530	COG0363	glucosamine-6-phosphate deaminase activity
RT761_RS10535	COG2271	Major facilitator Superfamily
RT761_RS10545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RT761_RS10560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RT761_RS10565	COG2239	Acts as a magnesium transporter
RT761_RS10570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RT761_RS10600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS10610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RT761_RS10620	COG1940	carbohydrate kinase activity
RT761_RS10635	COG1968	undecaprenyl-diphosphatase activity
RT761_RS10650	COG0009	L-threonylcarbamoyladenylate synthase
RT761_RS10675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RT761_RS10680	COG4145	pantothenate transmembrane transporter activity
RT761_RS10685	COG1063	alcohol dehydrogenase
RT761_RS10705	COG0395	ABC-type sugar transport system, permease component
RT761_RS10720	COG1192	Involved in chromosome partitioning
RT761_RS10725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RT761_RS10735	COG0741	lytic transglycosylase activity
RT761_RS10740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_RS10740	COG1796	DNA polymerase
RT761_RS10745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RT761_RS10750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RT761_RS10755	COG0066	3-isopropylmalate dehydratase activity
RT761_RS10760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RT761_RS10765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RT761_RS10770	COG2116	formate transmembrane transporter activity
RT761_RS10775	COG5012	cobalamin binding
RT761_RS10780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RT761_RS10785	COG0492	ferredoxin-NADP+ reductase activity
RT761_RS10840	COG0285	dihydrofolate synthase activity
RT761_RS10855	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RT761_RS10860	COG0047	phosphoribosylformylglycinamidine synthase activity
RT761_RS10865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RT761_RS10870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RT761_RS10875	COG0655	NAD(P)H dehydrogenase (quinone) activity
RT761_RS10885	COG1269	ATP hydrolysis coupled proton transport
RT761_RS10890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RT761_RS10910	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
RT761_RS10915	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
RT761_RS10920	COG1394	ATPase activity, coupled to movement of substances
RT761_RS10925	COG2801	Transposase and inactivated derivatives
RT761_RS10925	COG3415	Transposase
RT761_RS10950	COG3459	Glycosyltransferase 36 associated
RT761_RS10960	COG0395	ABC-type sugar transport system, permease component
RT761_RS10970	COG1609	Transcriptional regulator
RT761_RS10975	COG1349	DNA-binding transcription factor activity
RT761_RS10980	COG1175	transmembrane transport
RT761_RS10985	COG0395	ABC-type sugar transport system, permease component
RT761_RS11000	COG1349	DNA-binding transcription factor activity
RT761_RS11005	COG1653	transport
RT761_RS11010	COG1175	transmembrane transport
RT761_RS11015	COG0395	ABC-type sugar transport system, permease component
RT761_RS11030	COG1129	ABC transporter
RT761_RS11035	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS11040	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS11065	COG0395	ABC-type sugar transport system, permease component
RT761_RS11070	COG1175	transmembrane transport
RT761_RS11075	COG1653	transport
RT761_RS11085	COG2188	Transcriptional regulator
RT761_RS11095	COG1175	transmembrane transport
RT761_RS11100	COG0395	ABC-type sugar transport system, permease component
RT761_RS11105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RT761_RS11110	COG1609	Transcriptional regulator
RT761_RS11125	COG0395	ABC-type sugar transport system, permease component
RT761_RS11135	COG1882	Formate acetyltransferase
RT761_RS11140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RT761_RS11145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_RS11150	COG0022	dehydrogenase e1 component
RT761_RS11165	COG1484	DNA-dependent DNA replication
RT761_RS11170	COG4584	PFAM Integrase catalytic
RT761_RS11185	COG0420	3'-5' exonuclease activity
RT761_RS11190	COG4717	serine-type aminopeptidase activity
RT761_RS11205	COG2723	6-phospho-beta-galactosidase activity
RT761_RS11210	COG3534	alpha-L-arabinofuranosidase
RT761_RS11215	COG3534	alpha-L-arabinofuranosidase
RT761_RS11225	COG0444	Belongs to the ABC transporter superfamily
RT761_RS11235	COG0395	ABC-type sugar transport system, permease component
RT761_RS11240	COG1175	transmembrane transport
RT761_RS11250	COG0673	inositol 2-dehydrogenase activity
RT761_RS11275	COG1175	transmembrane transport
RT761_RS11280	COG0395	ABC-type sugar transport system, permease component
RT761_RS11435	COG1525	nuclease
RT761_RS11445	COG1484	DNA-dependent DNA replication
RT761_RS11450	COG4584	PFAM Integrase catalytic
RT761_RS11465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RT761_RS11510	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RT761_RS11520	COG1943	Transposase
RT761_RS11525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RT761_RS11530	COG1196	nuclear chromosome segregation
RT761_RS11545	COG1943	Transposase
RT761_RS11560	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_RS11585	COG1940	carbohydrate kinase activity
RT761_RS11590	COG2222	sugar isomerase
RT761_RS11615	COG1175	transmembrane transport
RT761_RS11620	COG0395	ABC-type sugar transport system, permease component
RT761_RS11635	COG2188	Transcriptional regulator
RT761_RS11660	COG1175	transmembrane transport
RT761_RS11665	COG0395	ABC-type sugar transport system, permease component
RT761_RS11670	COG4692	amylo-alpha-1,6-glucosidase activity
RT761_RS11680	COG2362	D-Aminopeptidase
RT761_RS11705	COG1070	Carbohydrate kinase
RT761_RS11715	COG0434	BtpA family
RT761_RS11725	COG1082	Xylose isomerase domain protein TIM barrel
RT761_RS11730	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS11735	COG4211	Belongs to the binding-protein-dependent transport system permease family
RT761_RS11740	COG1129	ABC transporter
RT761_RS11760	COG1175	transmembrane transport
RT761_RS11765	COG0395	ABC-type sugar transport system, permease component
RT761_RS11775	COG2199	diguanylate cyclase activity
RT761_RS11775	COG2203	Gaf domain
RT761_RS11775	COG2200	EAL domain
RT761_RS11790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RT761_RS11795	COG2133	pyrroloquinoline quinone binding
RT761_RS11805	COG2801	Transposase and inactivated derivatives
RT761_RS11805	COG3415	Transposase
RT761_RS11825	COG0719	Fe-S assembly protein
RT761_RS11840	COG1175	transmembrane transport
RT761_RS11845	COG0395	ABC-type sugar transport system, permease component
RT761_RS11850	COG0445	tRNA wobble uridine modification
RT761_RS11870	COG1175	transmembrane transport
RT761_RS11875	COG0395	ABC-type sugar transport system, permease component
RT761_RS11890	COG0445	tRNA wobble uridine modification
RT761_RS11905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RT761_RS11915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS11920	COG0395	ABC-type sugar transport system, permease component
RT761_RS11925	COG1175	transmembrane transport
RT761_RS11945	COG5001	Diguanylate cyclase
RT761_RS11970	COG3162	membrane
RT761_RS11980	COG0456	acetyltransferase
RT761_RS11985	COG1063	alcohol dehydrogenase
RT761_RS12015	COG2309	aminopeptidase activity
RT761_RS12025	COG3437	response regulator, receiver
RT761_RS12030	COG0673	inositol 2-dehydrogenase activity
RT761_RS12040	COG0823	Involved in the tonB-independent uptake of proteins
RT761_RS12065	COG0395	ABC-type sugar transport system, permease component
RT761_RS12070	COG1175	transmembrane transport
RT761_RS12120	COG0658	competence protein
RT761_RS12120	COG2333	competence protein COMEC
RT761_RS12140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RT761_RS12145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RT761_RS12155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RT761_RS12160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RT761_RS12170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RT761_RS12175	COG0736	holo-[acyl-carrier-protein] synthase activity
RT761_RS12180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RT761_RS12180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RT761_RS12185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RT761_RS12190	COG0802	atpase or kinase
RT761_RS12195	COG1214	PFAM Peptidase M22, glycoprotease
RT761_RS12205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RT761_RS12210	COG0459	protein refolding
RT761_RS12215	COG0516	GMP reductase activity
RT761_RS12220	COG0519	Catalyzes the synthesis of GMP from XMP
RT761_RS12220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RT761_RS12225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RT761_RS12230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RT761_RS12235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RT761_RS12240	COG0154	amidase activity
RT761_RS12245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RT761_RS12265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_RS12265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_RS12270	COG0297	glycogen (starch) synthase activity
RT761_RS12275	COG0237	dephospho-CoA kinase activity
RT761_RS12280	COG0556	nucleotide-excision repair
RT761_RS12285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RT761_RS12290	COG0322	excinuclease ABC activity
RT761_RS12295	COG1481	regulation of sporulation
RT761_RS12300	COG3842	ATPase activity
RT761_RS12310	COG0149	triose-phosphate isomerase activity
RT761_RS12330	COG0601	transmembrane transport
RT761_RS12335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_RS12340	COG0444	Belongs to the ABC transporter superfamily
RT761_RS12345	COG4608	Belongs to the ABC transporter superfamily
RT761_RS12350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RT761_RS12355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RT761_RS12360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RT761_RS12365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RT761_RS12370	COG0072	phenylalanine-tRNA ligase activity
RT761_RS12380	COG1193	negative regulation of DNA recombination
RT761_RS12385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RT761_RS12395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RT761_RS12400	COG0195	Participates in both transcription termination and antitermination
RT761_RS12405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RT761_RS12410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RT761_RS12420	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RT761_RS12430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RT761_RS12435	COG0196	riboflavin kinase activity
RT761_RS12440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RT761_RS12445	COG1185	polyribonucleotide nucleotidyltransferase activity
RT761_RS12450	COG1674	ftsk spoiiie
RT761_RS12460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_RS12465	COG1058	Belongs to the CinA family
RT761_RS12465	COG1546	Belongs to the CinA family
RT761_RS12475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RT761_RS12485	COG1418	mRNA catabolic process
RT761_RS12490	COG1692	metallophosphoesterase
RT761_RS12495	COG2359	stage V sporulation protein S
RT761_RS12500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_RS12505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RT761_RS12515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RT761_RS12525	COG0442	prolyl-tRNA aminoacylation
RT761_RS12530	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RT761_RS12535	COG0750	zinc metalloprotease
RT761_RS12540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RT761_RS12545	COG4589	Belongs to the CDS family
RT761_RS12550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RT761_RS12555	COG0233	cytoplasmic translational termination
RT761_RS12560	COG0528	UMP kinase activity
RT761_RS12570	COG0052	Belongs to the universal ribosomal protein uS2 family
RT761_RS12575	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RT761_RS12580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RT761_RS12590	COG1160	GTP binding
RT761_RS12595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RT761_RS12600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RT761_RS12605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RT761_RS12610	COG4401	Chorismate mutase type I
RT761_RS12620	COG1187	pseudouridine synthase activity
RT761_RS12625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RT761_RS12635	COG0180	Tryptophanyl-tRNA synthetase
RT761_RS12640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RT761_RS12640	COG0617	tRNA 3'-terminal CCA addition
RT761_RS12640	COG3620	sequence-specific DNA binding
RT761_RS12645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RT761_RS12650	COG0494	nUDIX hydrolase
RT761_RS12655	COG0617	tRNA 3'-terminal CCA addition
RT761_RS12655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RT761_RS12655	COG0517	IMP dehydrogenase activity
RT761_RS12670	COG0674	pyruvate-flavodoxin oxidoreductase activity
RT761_RS12670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RT761_RS12680	COG0497	DNA recombination
RT761_RS12685	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RT761_RS12690	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RT761_RS12695	COG0142	geranyltranstransferase activity
RT761_RS12700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RT761_RS12710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RT761_RS12720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RT761_RS12725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RT761_RS12730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RT761_RS12785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RT761_RS12790	COG4969	Belongs to the N-Me-Phe pilin family
RT761_RS12795	COG1459	type II secretion system
RT761_RS12810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RT761_RS12815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_RS12820	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RT761_RS12825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RT761_RS12830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RT761_RS12835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RT761_RS12840	COG1606	tRNA processing
RT761_RS12845	COG2183	response to ionizing radiation
RT761_RS12845	COG0539	negative regulation of cytoplasmic translation
RT761_RS12850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RT761_RS12855	COG0124	histidyl-tRNA synthetase
RT761_RS12860	COG1285	pathogenesis
RT761_RS12865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_RS12870	COG0138	bifunctional purine biosynthesis protein purh
RT761_RS12875	COG1069	ribulokinase activity
RT761_RS12885	COG0126	phosphoglycerate kinase activity
RT761_RS12900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RT761_RS12905	COG0481	GTPase activity
RT761_RS12940	COG0101	tRNA pseudouridine synthase activity
RT761_RS12945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RT761_RS12950	COG1122	ATPase activity
RT761_RS12955	COG1122	ATPase activity
RT761_RS12960	COG0203	ribosomal protein L17
RT761_RS12965	COG0202	RNA polymerase activity
RT761_RS12970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RT761_RS12975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RT761_RS12980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RT761_RS12985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RT761_RS12990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RT761_RS13000	COG0563	adenylate kinase activity
RT761_RS13005	COG0201	protein transport
RT761_RS13010	COG0200	Binds to the 23S rRNA
RT761_RS13015	COG1841	ribosomal large subunit assembly
RT761_RS13025	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RT761_RS13030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RT761_RS13035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RT761_RS13040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RT761_RS13050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RT761_RS13055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RT761_RS13060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RT761_RS13065	COG0255	Belongs to the universal ribosomal protein uL29 family
RT761_RS13070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RT761_RS13075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RT761_RS13080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RT761_RS13085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RT761_RS13090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RT761_RS13095	COG0089	rRNA binding
RT761_RS13100	COG0088	Forms part of the polypeptide exit tunnel
RT761_RS13105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RT761_RS13110	COG0051	transcription antitermination factor activity, RNA binding
RT761_RS13115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RT761_RS13120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RT761_RS13125	COG0049	tRNA binding
RT761_RS13130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RT761_RS13135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RT761_RS13135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RT761_RS13140	COG0085	RNA polymerase activity
RT761_RS13145	COG1355	regulation of microtubule-based process
RT761_RS13170	COG0071	Belongs to the small heat shock protein (HSP20) family
RT761_RS13200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RT761_RS13205	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
RT761_RS13210	COG0673	inositol 2-dehydrogenase activity
RT761_RS13220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RT761_RS13235	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RT761_RS13240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RT761_RS13250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RT761_RS13255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RT761_RS13290	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_RS13360	COG4584	PFAM Integrase catalytic
RT761_RS13425	COG2197	response regulator
RT761_RS13430	COG4585	Histidine kinase
RT761_RS13440	COG2197	response regulator
RT761_RS13455	COG2801	Transposase and inactivated derivatives
RT761_RS13455	COG3415	Transposase
RT761_RS13495	COG1129	ABC transporter
RT761_RS13500	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS13505	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_RS13515	COG0747	negative chemotaxis
RT761_RS13520	COG0601	transmembrane transport
RT761_RS13525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_RS13530	COG0444	Belongs to the ABC transporter superfamily
RT761_RS13535	COG4608	Belongs to the ABC transporter superfamily
RT761_RS13545	COG0460	homoserine dehydrogenase
RT761_RS13555	COG0765	amino acid transport
RT761_RS13560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RT761_RS13565	COG0305	Participates in initiation and elongation during chromosome replication
RT761_RS13570	COG0359	binds to the 23S rRNA
RT761_RS13580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RT761_RS13590	COG0360	Binds together with S18 to 16S ribosomal RNA
RT761_RS13595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RT761_RS13600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RT761_RS13605	COG0799	negative regulation of ribosome biogenesis
RT761_RS13610	COG1316	TRANSCRIPTIONal
RT761_RS13620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RT761_RS13625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RT761_RS13630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RT761_RS13635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_RS13640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RT761_RS13645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RT761_RS13650	COG1530	ribonuclease E activity
RT761_RS13665	COG0772	Belongs to the SEDS family
RT761_RS13670	COG0768	penicillin binding
RT761_RS13680	COG1792	Involved in formation and maintenance of cell shape
RT761_RS13685	COG1477	protein flavinylation
RT761_RS13695	COG2078	PFAM AMMECR1 domain protein
RT761_RS13695	COG3885	ferrous iron binding
RT761_RS13730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RT761_RS13730	COG4191	Histidine kinase
RT761_RS13740	COG0542	response to heat
RT761_RS13745	COG0789	Transcriptional regulator
RT761_RS13770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RT761_RS13775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RT761_RS13785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RT761_RS13790	COG1085	galactose-1-phosphate uridylyltransferase
RT761_RS13800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RT761_RS13815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RT761_RS13830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RT761_RS13835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_RS13845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_RS13850	COG0647	UMP catabolic process
RT761_RS13855	COG1131	(ABC) transporter
RT761_RS13875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RT761_RS13880	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RT761_RS13900	COG1691	(AIR) carboxylase
RT761_RS13905	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
RT761_RS13920	COG0411	ABC transporter
RT761_RS13930	COG0559	Belongs to the binding-protein-dependent transport system permease family
RT761_RS13965	COG1659	Linocin_M18 bacteriocin protein
RT761_RS13970	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RT761_RS13995	COG1136	(ABC) transporter
RT761_RS14000	COG4591	ABC-type transport system involved in lipoprotein release permease component
RT761_RS14010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RT761_RS14015	COG3189	MarR family transcriptional regulator
RT761_RS14060	COG0512	Glutamine amidotransferase of anthranilate synthase
RT761_RS14115	COG1555	photosystem II stabilization
RT761_RS14115	COG1596	polysaccharide export