locus-tag	class	description
AUMI_RS00020	COG0174	glutamine synthetase
AUMI_RS00025	COG0519	Catalyzes the synthesis of GMP from XMP
AUMI_RS00035	COG1846	Transcriptional regulator
AUMI_RS00040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUMI_RS00050	COG2078	PFAM AMMECR1 domain protein
AUMI_RS00050	COG3885	ferrous iron binding
AUMI_RS00065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AUMI_RS00070	COG1064	alcohol dehydrogenase
AUMI_RS00075	COG2957	Belongs to the agmatine deiminase family
AUMI_RS00080	COG0076	glutamate decarboxylase activity
AUMI_RS00090	COG2030	dehydratase
AUMI_RS00100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUMI_RS00110	COG0436	Aminotransferase
AUMI_RS00120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUMI_RS00130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUMI_RS00135	COG0081	regulation of translation
AUMI_RS00140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AUMI_RS00155	COG0745	RESPONSE REGULATOR receiver
AUMI_RS00160	COG2205	protein histidine kinase activity
AUMI_RS00165	COG1105	Belongs to the carbohydrate kinase PfkB family
AUMI_RS00170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUMI_RS00175	COG0222	ribosome binding
AUMI_RS00190	COG4214	carbohydrate transport
AUMI_RS00200	COG4213	ABC transporter substrate-binding protein
AUMI_RS00205	COG1070	Carbohydrate kinase
AUMI_RS00210	COG2115	Belongs to the xylose isomerase family
AUMI_RS00215	COG1940	carbohydrate kinase activity
AUMI_RS00220	COG0673	inositol 2-dehydrogenase activity
AUMI_RS00225	COG0137	argininosuccinate synthase activity
AUMI_RS00280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AUMI_RS00295	COG0579	oxidoreductase
AUMI_RS00320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AUMI_RS00330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUMI_RS00340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AUMI_RS00370	COG1754	DNA topoisomerase type I activity
AUMI_RS00370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUMI_RS00375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUMI_RS00380	COG0470	DNA polymerase III
AUMI_RS00425	COG1132	(ABC) transporter
AUMI_RS00435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUMI_RS00440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUMI_RS00440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUMI_RS00455	COG0180	Tryptophanyl-tRNA synthetase
AUMI_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUMI_RS00485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUMI_RS00485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUMI_RS00485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUMI_RS00495	COG1349	DNA-binding transcription factor activity
AUMI_RS00500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUMI_RS00520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AUMI_RS00525	COG1053	succinate dehydrogenase
AUMI_RS00535	COG2009	succinate dehydrogenase
AUMI_RS00540	COG0662	Cupin 2, conserved barrel domain protein
AUMI_RS00540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AUMI_RS00545	COG0295	cytidine deaminase activity
AUMI_RS00555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AUMI_RS00570	COG4770	biotin carboxylase activity
AUMI_RS00575	COG0424	maF-like protein
AUMI_RS00580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUMI_RS00590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AUMI_RS00605	COG0463	Glycosyl transferase, family 2
AUMI_RS00625	COG1316	TRANSCRIPTIONal
AUMI_RS00670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUMI_RS00675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AUMI_RS00685	COG5000	phosphorelay sensor kinase activity
AUMI_RS00685	COG5002	protein histidine kinase activity
AUMI_RS00690	COG5401	PFAM Sporulation and spore germination
AUMI_RS00695	COG1040	competence protein
AUMI_RS00705	COG0653	protein targeting
AUMI_RS00775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AUMI_RS00780	COG1024	Enoyl-CoA hydratase
AUMI_RS00780	COG1250	3-hydroxyacyl-CoA dehydrogenase
AUMI_RS00790	COG3594	Acyltransferase
AUMI_RS00795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AUMI_RS00800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUMI_RS00840	COG1088	dTDP-glucose 4,6-dehydratase activity
AUMI_RS00850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUMI_RS00855	COG1162	GTPase activity
AUMI_RS00860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUMI_RS00865	COG1595	DNA-templated transcription, initiation
AUMI_RS00880	COG0567	Dehydrogenase, E1 component
AUMI_RS00880	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUMI_RS00885	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AUMI_RS00920	COG1442	glycosyl transferase family 8
AUMI_RS00920	COG1216	Glycosyl transferase, family 2
AUMI_RS00925	COG2226	methyltransferase
AUMI_RS00985	COG0018	arginyl-trna synthetase
AUMI_RS00995	COG0460	homoserine dehydrogenase
AUMI_RS01005	COG0083	homoserine kinase activity
AUMI_RS01020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUMI_RS01025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AUMI_RS01040	COG1045	serine acetyltransferase
AUMI_RS01050	COG2890	protein-(glutamine-N5) methyltransferase activity
AUMI_RS01060	COG0009	L-threonylcarbamoyladenylate synthase
AUMI_RS01065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUMI_RS01075	COG0356	it plays a direct role in the translocation of protons across the membrane
AUMI_RS01080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUMI_RS01085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUMI_RS01090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUMI_RS01095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUMI_RS01100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUMI_RS01105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUMI_RS01110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUMI_RS01115	COG3022	response to hydroperoxide
AUMI_RS01155	COG0384	phenazine biosynthesis protein PhzF
AUMI_RS01160	COG0586	Pfam SNARE associated Golgi protein
AUMI_RS01180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AUMI_RS01185	COG0571	ribonuclease III activity
AUMI_RS01190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUMI_RS01200	COG1414	Transcriptional regulator
AUMI_RS01215	COG0631	protein serine/threonine phosphatase activity
AUMI_RS01230	COG0714	Associated with various cellular activities
AUMI_RS01250	COG0433	COG0433 Predicted ATPase
AUMI_RS01250	COG1674	ftsk spoiiie
AUMI_RS01265	COG3485	protocatechuate 3,4-dioxygenase
AUMI_RS01290	COG2884	Cell division ATP-binding protein ftsE
AUMI_RS01295	COG2177	Part of the ABC transporter FtsEX involved in
AUMI_RS01300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AUMI_RS01310	COG1247	-acetyltransferase
AUMI_RS01330	COG0463	Glycosyl transferase, family 2
AUMI_RS01340	COG0386	Belongs to the glutathione peroxidase family
AUMI_RS01355	COG0483	inositol monophosphate 1-phosphatase activity
AUMI_RS01365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AUMI_RS01375	COG0010	Belongs to the arginase family
AUMI_RS01380	COG1228	amidohydrolase
AUMI_RS01385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AUMI_RS01390	COG2986	histidine ammonia-lyase
AUMI_RS01400	COG2076	Multidrug Resistance protein
AUMI_RS01410	COG0702	epimerase
AUMI_RS01435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AUMI_RS01445	COG2267	carboxylic ester hydrolase activity
AUMI_RS01450	COG2252	PERMEase
AUMI_RS01470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUMI_RS01500	COG0210	DNA helicase
AUMI_RS01530	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUMI_RS01535	COG1615	UPF0182 protein
AUMI_RS01545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUMI_RS01550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AUMI_RS01555	COG1082	Xylose isomerase domain protein TIM barrel
AUMI_RS01560	COG0129	dihydroxy-acid dehydratase activity
AUMI_RS01570	COG0440	acetolactate synthase activity
AUMI_RS01575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AUMI_RS01595	COG0473	3-isopropylmalate dehydrogenase activity
AUMI_RS01600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUMI_RS01605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AUMI_RS01635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AUMI_RS01640	COG0066	3-isopropylmalate dehydratase activity
AUMI_RS01645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUMI_RS01655	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUMI_RS01660	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUMI_RS01680	COG0742	ribosomal rna small subunit methyltransferase
AUMI_RS01690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUMI_RS01695	COG0552	protein localization to endoplasmic reticulum
AUMI_RS01705	COG1116	anion transmembrane transporter activity
AUMI_RS01715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUMI_RS01720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUMI_RS01730	COG2873	o-acetylhomoserine
AUMI_RS01735	COG1832	CoA-binding protein
AUMI_RS01740	COG0228	four-way junction DNA binding
AUMI_RS01745	COG1837	Belongs to the UPF0109 family
AUMI_RS01750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUMI_RS01755	COG0336	Belongs to the RNA methyltransferase TrmD family
AUMI_RS01760	COG0335	large ribosomal subunit rRNA binding
AUMI_RS01770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUMI_RS01785	COG4974	Belongs to the 'phage' integrase family
AUMI_RS01800	COG1090	epimerase
AUMI_RS01815	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AUMI_RS01820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUMI_RS01825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AUMI_RS01830	COG1609	Transcriptional regulator
AUMI_RS01855	COG0366	Alpha amylase catalytic
AUMI_RS01860	COG1674	ftsk spoiiie
AUMI_RS01870	COG1058	Belongs to the CinA family
AUMI_RS01870	COG1546	Belongs to the CinA family
AUMI_RS01875	COG1396	sequence-specific DNA binding
AUMI_RS01885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUMI_RS01900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AUMI_RS01905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUMI_RS01910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AUMI_RS01920	COG2813	Specifically methylates the guanine in position
AUMI_RS01930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AUMI_RS01955	COG0495	leucyl-tRNA aminoacylation
AUMI_RS01960	COG2815	serine threonine protein kinase
AUMI_RS01960	COG0515	serine threonine protein kinase
AUMI_RS01975	COG0142	geranyltranstransferase activity
AUMI_RS01985	COG2001	Belongs to the MraZ family
AUMI_RS01990	COG0275	rRNA processing
AUMI_RS02000	COG0768	penicillin binding
AUMI_RS02010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUMI_RS02015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUMI_RS02025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUMI_RS02030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUMI_RS02040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AUMI_RS02045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AUMI_RS02050	COG1799	cell septum assembly
AUMI_RS02060	COG3599	regulation of cell shape
AUMI_RS02065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AUMI_RS02075	COG1660	Displays ATPase and GTPase activities
AUMI_RS02080	COG1481	regulation of sporulation
AUMI_RS02090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AUMI_RS02095	COG0126	phosphoglycerate kinase activity
AUMI_RS02100	COG0149	triose-phosphate isomerase activity
AUMI_RS02105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUMI_RS02115	COG0363	glucosamine-6-phosphate deaminase activity
AUMI_RS02130	COG0166	Belongs to the GPI family
AUMI_RS02135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AUMI_RS02145	COG0109	protoheme IX farnesyltransferase activity
AUMI_RS02165	COG2146	nitrite reductase [NAD(P)H] activity
AUMI_RS02170	COG0396	ATPase activity
AUMI_RS02175	COG2151	metal-sulfur cluster biosynthetic enzyme
AUMI_RS02190	COG0488	(ABC) transporter
AUMI_RS02200	COG2860	membrane
AUMI_RS02205	COG1381	Involved in DNA repair and RecF pathway recombination
AUMI_RS02210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUMI_RS02235	COG0358	DNA primase activity
AUMI_RS02260	COG0242	peptide deformylase activity
AUMI_RS02270	COG0438	transferase activity, transferring glycosyl groups
AUMI_RS02280	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AUMI_RS02290	COG1309	transcriptional regulator
AUMI_RS02295	COG2197	response regulator
AUMI_RS02320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AUMI_RS02325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUMI_RS02330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUMI_RS02345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AUMI_RS02365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUMI_RS02400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AUMI_RS02405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AUMI_RS02405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AUMI_RS02415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AUMI_RS02420	COG0174	glutamine synthetase
AUMI_RS02435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AUMI_RS02440	COG0321	lipoyl(octanoyl) transferase activity
AUMI_RS02450	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUMI_RS02455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUMI_RS02460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AUMI_RS02470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUMI_RS02485	COG0187	DNA topoisomerase II activity
AUMI_RS02490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUMI_RS02515	COG0756	dUTP diphosphatase activity
AUMI_RS02530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AUMI_RS02535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AUMI_RS02540	COG1024	Enoyl-CoA hydratase
AUMI_RS02540	COG1250	3-hydroxyacyl-CoA dehydrogenase
AUMI_RS02545	COG0183	Belongs to the thiolase family
AUMI_RS02605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUMI_RS02615	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AUMI_RS02620	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AUMI_RS02625	COG0217	transcriptional regulatory protein
AUMI_RS02630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AUMI_RS02635	COG0632	four-way junction helicase activity
AUMI_RS02640	COG2255	four-way junction helicase activity
AUMI_RS02650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AUMI_RS02655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AUMI_RS02660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUMI_RS02685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUMI_RS02695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUMI_RS02700	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AUMI_RS02710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUMI_RS02715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUMI_RS02725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUMI_RS02730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AUMI_RS02735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUMI_RS02740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUMI_RS02745	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AUMI_RS02750	COG0540	Belongs to the ATCase OTCase family
AUMI_RS02755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUMI_RS02765	COG0505	Belongs to the CarA family
AUMI_RS02770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUMI_RS02775	COG0284	orotidine-5'-phosphate decarboxylase activity
AUMI_RS02780	COG0194	GDP metabolic process
AUMI_RS02785	COG1758	RNA polymerase activity
AUMI_RS02795	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUMI_RS02805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUMI_RS02815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUMI_RS02820	COG0140	phosphoribosyl-ATP diphosphatase activity
AUMI_RS02825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AUMI_RS02830	COG0107	imidazoleglycerol-phosphate synthase activity
AUMI_RS02855	COG0134	indole-3-glycerol-phosphate synthase activity
AUMI_RS02860	COG0133	tryptophan synthase activity
AUMI_RS02865	COG0159	tryptophan synthase activity
AUMI_RS02870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AUMI_RS02875	COG0067	glutamate synthase
AUMI_RS02875	COG0069	glutamate synthase activity
AUMI_RS02875	COG0070	glutamate synthase
AUMI_RS02885	COG0469	pyruvate kinase activity
AUMI_RS02900	COG2050	protein possibly involved in aromatic compounds catabolism
AUMI_RS02910	COG0539	negative regulation of cytoplasmic translation
AUMI_RS02915	COG0237	dephospho-CoA kinase activity
AUMI_RS02920	COG0556	nucleotide-excision repair
AUMI_RS02930	COG0322	excinuclease ABC activity
AUMI_RS02935	COG0584	glycerophosphoryl diester phosphodiesterase
AUMI_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS02955	COG0738	Major facilitator superfamily
AUMI_RS02960	COG0738	Major facilitator superfamily
AUMI_RS02965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUMI_RS02970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AUMI_RS02975	COG1845	cytochrome c oxidase, subunit III
AUMI_RS02980	COG2010	Cytochrome c
AUMI_RS02985	COG0723	plastoquinol--plastocyanin reductase activity
AUMI_RS02990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AUMI_RS03000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AUMI_RS03005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AUMI_RS03025	COG0167	dihydroorotate dehydrogenase activity
AUMI_RS03030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AUMI_RS03035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AUMI_RS03040	COG0587	DNA-directed DNA polymerase activity
AUMI_RS03055	COG0805	protein transport
AUMI_RS03060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AUMI_RS03070	COG2378	regulation of single-species biofilm formation
AUMI_RS03075	COG0545	Peptidyl-prolyl cis-trans isomerase
AUMI_RS03085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUMI_RS03095	COG1968	undecaprenyl-diphosphatase activity
AUMI_RS03140	COG0254	rRNA binding
AUMI_RS03145	COG1119	ATPase activity
AUMI_RS03150	COG0297	glycogen (starch) synthase activity
AUMI_RS03155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUMI_RS03180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AUMI_RS03185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUMI_RS03195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUMI_RS03205	COG0537	adenosine 5'-monophosphoramidase activity
AUMI_RS03210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AUMI_RS03215	COG0484	heat shock protein binding
AUMI_RS03220	COG1420	regulation of RNA biosynthetic process
AUMI_RS03235	COG0481	GTPase activity
AUMI_RS03240	COG0268	Binds directly to 16S ribosomal RNA
AUMI_RS03255	COG1555	photosystem II stabilization
AUMI_RS03255	COG1596	polysaccharide export
AUMI_RS03260	COG4129	membrane
AUMI_RS03265	COG1472	Belongs to the glycosyl hydrolase 3 family
AUMI_RS03285	COG3842	ATPase activity
AUMI_RS03295	COG2824	Alkylphosphonate utilization operon protein PhnA
AUMI_RS03305	COG0799	negative regulation of ribosome biogenesis
AUMI_RS03315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUMI_RS03325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AUMI_RS03330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AUMI_RS03335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUMI_RS03340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUMI_RS03345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUMI_RS03350	COG1530	ribonuclease E activity
AUMI_RS03360	COG0477	Major facilitator Superfamily
AUMI_RS03365	COG0105	UTP biosynthetic process
AUMI_RS03375	COG0285	dihydrofolate synthase activity
AUMI_RS03380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AUMI_RS03385	COG0525	valine-tRNA ligase activity
AUMI_RS03400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AUMI_RS03405	COG0531	amino acid
AUMI_RS03410	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AUMI_RS03420	COG1940	carbohydrate kinase activity
AUMI_RS03440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUMI_RS03445	COG1192	Involved in chromosome partitioning
AUMI_RS03460	COG1716	ATPase activity
AUMI_RS03465	COG0513	Belongs to the DEAD box helicase family
AUMI_RS03470	COG3046	protein related to deoxyribodipyrimidine photolyase
AUMI_RS03475	COG0697	spore germination
AUMI_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS03500	COG1280	lysine exporter protein (LysE YggA)
AUMI_RS03505	COG4702	Belongs to the UPF0303 family
AUMI_RS03530	COG2814	Major facilitator Superfamily
AUMI_RS03535	COG0402	S-adenosylhomocysteine deaminase activity
AUMI_RS03555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AUMI_RS03575	COG1160	GTP binding
AUMI_RS03580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUMI_RS03595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUMI_RS03615	COG0494	nUDIX hydrolase
AUMI_RS03620	COG0504	CTP synthase activity
AUMI_RS03625	COG0497	DNA recombination
AUMI_RS03630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUMI_RS03645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AUMI_RS03650	COG2079	MmgE PrpD family protein
AUMI_RS03655	COG1802	Transcriptional regulator
AUMI_RS03670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AUMI_RS03685	COG0647	UMP catabolic process
AUMI_RS03710	COG1794	racemase activity, acting on amino acids and derivatives
AUMI_RS03720	COG0367	asparagine synthase
AUMI_RS03725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUMI_RS03730	COG0165	Argininosuccinate lyase
AUMI_RS03740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUMI_RS03745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AUMI_RS03750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUMI_RS03755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUMI_RS03760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUMI_RS03760	COG0072	phenylalanine-tRNA ligase activity
AUMI_RS03765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUMI_RS03770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUMI_RS03775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUMI_RS03780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUMI_RS03785	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AUMI_RS03800	COG2409	Drug exporters of the RND superfamily
AUMI_RS03815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AUMI_RS03820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AUMI_RS03825	COG0131	Imidazoleglycerol-phosphate dehydratase
AUMI_RS03830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AUMI_RS03840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUMI_RS03845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AUMI_RS03850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUMI_RS03855	COG0740	serine-type endopeptidase activity
AUMI_RS03860	COG0740	serine-type endopeptidase activity
AUMI_RS03875	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUMI_RS03890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUMI_RS03895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUMI_RS03910	COG0698	ribose 5-phosphate isomerase
AUMI_RS03920	COG0668	transmembrane transport
AUMI_RS03935	COG1946	Acyl-CoA thioesterase
AUMI_RS03965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUMI_RS03975	COG1253	flavin adenine dinucleotide binding
AUMI_RS03985	COG1012	belongs to the aldehyde dehydrogenase family
AUMI_RS03990	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AUMI_RS04010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUMI_RS04020	COG1122	ATPase activity
AUMI_RS04025	COG4721	ABC-type cobalt transport system, permease component
AUMI_RS04035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUMI_RS04040	COG0154	amidase activity
AUMI_RS04045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUMI_RS04050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUMI_RS04055	COG0482	sulfurtransferase activity
AUMI_RS04070	COG0366	Alpha amylase catalytic
AUMI_RS04075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUMI_RS04125	COG0233	cytoplasmic translational termination
AUMI_RS04130	COG0528	UMP kinase activity
AUMI_RS04135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUMI_RS04140	COG0052	Belongs to the universal ribosomal protein uS2 family
AUMI_RS04145	COG0477	Major facilitator Superfamily
AUMI_RS04150	COG0739	heme binding
AUMI_RS04160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUMI_RS04170	COG0612	Peptidase, M16
AUMI_RS04175	COG0667	Aldo Keto reductase
AUMI_RS04180	COG1185	polyribonucleotide nucleotidyltransferase activity
AUMI_RS04185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUMI_RS04205	COG1872	DUF167
AUMI_RS04215	COG0545	Peptidyl-prolyl cis-trans isomerase
AUMI_RS04220	COG0833	amino acid
AUMI_RS04230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUMI_RS04235	COG1012	belongs to the aldehyde dehydrogenase family
AUMI_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS04245	COG2188	Transcriptional regulator
AUMI_RS04250	COG0531	amino acid
AUMI_RS04265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUMI_RS04280	COG1012	belongs to the aldehyde dehydrogenase family
AUMI_RS04285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AUMI_RS04290	COG0196	riboflavin kinase activity
AUMI_RS04305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUMI_RS04325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUMI_RS04330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUMI_RS04345	COG0442	prolyl-tRNA aminoacylation
AUMI_RS04355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AUMI_RS04360	COG0750	zinc metalloprotease
AUMI_RS04365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AUMI_RS04370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AUMI_RS04385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUMI_RS04390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AUMI_RS04395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUMI_RS04405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AUMI_RS04420	COG1960	acyl-CoA dehydrogenase activity
AUMI_RS04440	COG0513	Belongs to the DEAD box helicase family
AUMI_RS04450	COG0697	spore germination
AUMI_RS04465	COG0006	proline dipeptidase activity
AUMI_RS04480	COG1012	belongs to the aldehyde dehydrogenase family
AUMI_RS04485	COG2239	Acts as a magnesium transporter
AUMI_RS04500	COG1012	belongs to the aldehyde dehydrogenase family
AUMI_RS04510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AUMI_RS04520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUMI_RS04525	COG2818	Glycosylase
AUMI_RS04530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AUMI_RS04550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUMI_RS04585	COG0672	)-iron permease
AUMI_RS04590	COG1217	gtp-binding protein TYPA
AUMI_RS04615	COG1335	isochorismatase
AUMI_RS04625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AUMI_RS04625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AUMI_RS04630	COG0509	glycine decarboxylation via glycine cleavage system
AUMI_RS04635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AUMI_RS04645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AUMI_RS04650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AUMI_RS04660	COG1104	cysteine desulfurase activity
AUMI_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS04700	COG4221	oxidoreductase activity
AUMI_RS04725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUMI_RS04730	COG0012	GTP binding
AUMI_RS04750	COG1322	Protein conserved in bacteria
AUMI_RS04765	COG0191	fructose-bisphosphate aldolase activity
AUMI_RS04775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AUMI_RS04780	COG1570	exodeoxyribonuclease VII activity
AUMI_RS04785	COG0604	alcohol dehydrogenase
AUMI_RS04790	COG1722	exodeoxyribonuclease VII activity
AUMI_RS04800	COG0288	reversible hydration of carbon dioxide
AUMI_RS04805	COG0114	fumarate hydratase activity
AUMI_RS04810	COG0667	Aldo Keto reductase
AUMI_RS04840	COG2159	amidohydrolase
AUMI_RS04850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AUMI_RS04855	COG1414	Transcriptional regulator
AUMI_RS04890	COG0633	Ferredoxin
AUMI_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS04910	COG0574	Belongs to the PEP-utilizing enzyme family
AUMI_RS04910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUMI_RS04920	COG1414	Transcriptional regulator
AUMI_RS04935	COG2301	Belongs to the HpcH HpaI aldolase family
AUMI_RS04940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AUMI_RS04950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AUMI_RS04955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUMI_RS04980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUMI_RS04985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AUMI_RS04990	COG0501	Belongs to the peptidase M48B family
AUMI_RS04995	COG1704	LemA family
AUMI_RS05010	COG2161	toxin-antitoxin pair type II binding
AUMI_RS05015	COG2026	Addiction module toxin, RelE StbE family
AUMI_RS05030	COG1252	NADH dehydrogenase
AUMI_RS05035	COG1404	Belongs to the peptidase S8 family
AUMI_RS05050	COG0148	phosphopyruvate hydratase activity
AUMI_RS05055	COG0124	histidyl-tRNA synthetase
AUMI_RS05070	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AUMI_RS05080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AUMI_RS05095	COG0193	aminoacyl-tRNA hydrolase activity
AUMI_RS05100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AUMI_RS05110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUMI_RS05120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUMI_RS05125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AUMI_RS05135	COG1846	Transcriptional regulator
AUMI_RS05140	COG0488	(ABC) transporter
AUMI_RS05145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AUMI_RS05150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUMI_RS05155	COG0084	hydrolase, TatD family'
AUMI_RS05160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUMI_RS05165	COG3842	ATPase activity
AUMI_RS05190	COG1760	l-serine dehydratase
AUMI_RS05195	COG2040	homocysteine
AUMI_RS05200	COG0477	Major facilitator Superfamily
AUMI_RS05205	COG1643	Atp-dependent helicase
AUMI_RS05220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUMI_RS05225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUMI_RS05225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AUMI_RS05235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AUMI_RS05240	COG0259	pyridoxamine-phosphate oxidase activity
AUMI_RS05280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AUMI_RS05310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AUMI_RS05320	COG1278	Cold shock
AUMI_RS05340	COG0745	RESPONSE REGULATOR receiver
AUMI_RS05345	COG2205	protein histidine kinase activity
AUMI_RS05355	COG0459	protein refolding
AUMI_RS05360	COG1470	cell adhesion involved in biofilm formation
AUMI_RS05365	COG1278	Cold shock
AUMI_RS05390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUMI_RS05395	COG0215	cysteine-tRNA ligase activity
AUMI_RS05400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AUMI_RS05400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AUMI_RS05415	COG0588	phosphoglycerate mutase activity
AUMI_RS05430	COG0745	RESPONSE REGULATOR receiver
AUMI_RS05435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUMI_RS05440	COG0406	alpha-ribazole phosphatase activity
AUMI_RS05440	COG0494	nUDIX hydrolase
AUMI_RS05450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AUMI_RS05695	COG1741	Belongs to the pirin family
AUMI_RS05715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUMI_RS05720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUMI_RS05735	COG3384	dioxygenase
AUMI_RS05755	COG2217	Heavy metal translocating P-type atpase
AUMI_RS05760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AUMI_RS05760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AUMI_RS05765	COG0604	alcohol dehydrogenase
AUMI_RS05770	COG0076	glutamate decarboxylase activity
AUMI_RS05775	COG1982	Orn Lys Arg decarboxylase major
AUMI_RS05780	COG1132	(ABC) transporter
AUMI_RS05785	COG1132	(ABC) transporter
AUMI_RS05875	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AUMI_RS05910	COG0210	DNA helicase
AUMI_RS05915	COG0514	ATP-dependent DNA helicase (RecQ)
AUMI_RS05990	COG0516	GMP reductase activity
AUMI_RS05995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AUMI_RS06010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AUMI_RS06010	COG0519	Catalyzes the synthesis of GMP from XMP
AUMI_RS06035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUMI_RS06050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUMI_RS06055	COG0456	acetyltransferase
AUMI_RS06055	COG1214	PFAM Peptidase M22, glycoprotease
AUMI_RS06065	COG0802	atpase or kinase
AUMI_RS06070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUMI_RS06075	COG0736	holo-[acyl-carrier-protein] synthase activity
AUMI_RS06080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUMI_RS06085	COG1072	(Pantothenic acid kinase))
AUMI_RS06090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUMI_RS06095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AUMI_RS06100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUMI_RS06105	COG0101	tRNA pseudouridine synthase activity
AUMI_RS06110	COG0203	ribosomal protein L17
AUMI_RS06115	COG0202	RNA polymerase activity
AUMI_RS06120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUMI_RS06125	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AUMI_RS06130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUMI_RS06135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUMI_RS06140	COG0024	Methionine aminopeptidase
AUMI_RS06145	COG0563	adenylate kinase activity
AUMI_RS06155	COG0200	Binds to the 23S rRNA
AUMI_RS06160	COG1841	ribosomal large subunit assembly
AUMI_RS06165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUMI_RS06170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AUMI_RS06175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUMI_RS06180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUMI_RS06185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUMI_RS06190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUMI_RS06195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUMI_RS06200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AUMI_RS06205	COG0255	Belongs to the universal ribosomal protein uL29 family
AUMI_RS06210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUMI_RS06215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUMI_RS06220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUMI_RS06225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUMI_RS06230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUMI_RS06235	COG0089	rRNA binding
AUMI_RS06240	COG0088	Forms part of the polypeptide exit tunnel
AUMI_RS06245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUMI_RS06250	COG0051	transcription antitermination factor activity, RNA binding
AUMI_RS06255	COG0659	secondary active sulfate transmembrane transporter activity
AUMI_RS06265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AUMI_RS06270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUMI_RS06275	COG0049	tRNA binding
AUMI_RS06280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUMI_RS06290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AUMI_RS06295	COG0085	RNA polymerase activity
AUMI_RS06335	COG4886	Leucine-rich repeat (LRR) protein
AUMI_RS06365	COG3850	Histidine kinase
AUMI_RS06395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AUMI_RS06420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AUMI_RS06445	COG0667	Aldo Keto reductase
AUMI_RS06450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AUMI_RS06460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUMI_RS06465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AUMI_RS06480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AUMI_RS06485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AUMI_RS06495	COG0302	gtp cyclohydrolase
AUMI_RS06500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AUMI_RS06510	COG0037	tRNA processing
AUMI_RS06515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AUMI_RS06520	COG0741	lytic transglycosylase activity
AUMI_RS06520	COG1196	nuclear chromosome segregation
AUMI_RS06520	COG0739	heme binding
AUMI_RS06540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AUMI_RS06545	COG3253	May function as heme-dependent peroxidase
AUMI_RS06550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AUMI_RS06555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AUMI_RS06560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AUMI_RS06565	COG0181	hydroxymethylbilane synthase activity
AUMI_RS06575	COG0113	porphobilinogen synthase activity
AUMI_RS06580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AUMI_RS06590	COG0038	chloride channel
AUMI_RS06625	COG1410	methionine synthase
AUMI_RS06625	COG0646	methionine synthase
AUMI_RS06640	COG2326	polyphosphate kinase activity
AUMI_RS06655	COG1914	H( )-stimulated, divalent metal cation uptake system
AUMI_RS06675	COG0513	Belongs to the DEAD box helicase family
AUMI_RS06685	COG1316	TRANSCRIPTIONal
AUMI_RS06700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUMI_RS06705	COG0077	Prephenate dehydratase
AUMI_RS06715	COG1876	peptidase activity
AUMI_RS06720	COG1733	regulation of RNA biosynthetic process
AUMI_RS06725	COG0477	Major facilitator Superfamily
AUMI_RS06740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AUMI_RS06750	COG2267	carboxylic ester hydrolase activity
AUMI_RS06755	COG3104	oligopeptide transport
AUMI_RS06765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUMI_RS06770	COG1522	sequence-specific DNA binding
AUMI_RS06780	COG1280	lysine exporter protein (LysE YggA)
AUMI_RS06785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUMI_RS06790	COG0022	dehydrogenase e1 component
AUMI_RS06815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUMI_RS06825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUMI_RS06840	COG0776	regulation of translation
AUMI_RS06845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUMI_RS06850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUMI_RS06855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUMI_RS06860	COG0735	belongs to the Fur family
AUMI_RS06870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUMI_RS06875	COG1121	(ABC) transporter
AUMI_RS06880	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUMI_RS06880	COG3443	Belongs to the bacterial solute-binding protein 9 family
AUMI_RS06885	COG1054	Belongs to the UPF0176 family
AUMI_RS06915	COG0423	glycine-tRNA ligase activity
AUMI_RS06920	COG3590	peptidase
AUMI_RS06935	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AUMI_RS06970	COG1477	protein flavinylation
AUMI_RS06985	COG0745	RESPONSE REGULATOR receiver
AUMI_RS06990	COG5002	protein histidine kinase activity
AUMI_RS06995	COG1716	ATPase activity
AUMI_RS07015	COG0768	penicillin binding
AUMI_RS07020	COG0515	serine threonine protein kinase
AUMI_RS07025	COG0515	serine threonine protein kinase
AUMI_RS07035	COG3764	Sortase (surface protein transpeptidase)
AUMI_RS07045	COG0705	Rhomboid family
AUMI_RS07045	COG0457	Tetratricopeptide repeat
AUMI_RS07090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUMI_RS07095	COG0187	DNA topoisomerase II activity
AUMI_RS07100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AUMI_RS07105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUMI_RS07110	COG0592	DNA-directed DNA polymerase activity
AUMI_RS07115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUMI_RS07120	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AUMI_RS07130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AUMI_RS07135	COG0706	membrane insertase activity
AUMI_RS07145	COG0357	Ribosomal RNA small subunit methyltransferase G
AUMI_RS07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AUMI_RS07170	COG3118	belongs to the thioredoxin family
AUMI_RS07175	COG0492	ferredoxin-NADP+ reductase activity
AUMI_RS07190	COG0617	tRNA 3'-terminal CCA addition
AUMI_RS07195	COG0360	Binds together with S18 to 16S ribosomal RNA
AUMI_RS07205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUMI_RS07210	COG0359	binds to the 23S rRNA
AUMI_RS07215	COG0305	Participates in initiation and elongation during chromosome replication
AUMI_RS07230	COG0717	Belongs to the dCTP deaminase family
AUMI_RS07235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUMI_RS07240	COG0142	geranyltranstransferase activity
AUMI_RS07250	COG1233	COG1233 Phytoene dehydrogenase and related
AUMI_RS07270	COG1902	pentaerythritol trinitrate reductase activity
AUMI_RS07280	COG0443	Heat shock 70 kDa protein
AUMI_RS07285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AUMI_RS07290	COG0484	heat shock protein binding
AUMI_RS07295	COG0789	Transcriptional regulator
AUMI_RS07310	COG2813	Specifically methylates the guanine in position
AUMI_RS07320	COG0542	response to heat
AUMI_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
AUMI_RS07435	COG0009	L-threonylcarbamoyladenylate synthase
AUMI_RS07440	COG1231	oxidoreductase activity
AUMI_RS07455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AUMI_RS07485	COG0415	Belongs to the DNA photolyase family
AUMI_RS07490	COG0745	RESPONSE REGULATOR receiver
AUMI_RS07495	COG0590	tRNA wobble adenosine to inosine editing
AUMI_RS07505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUMI_RS07510	COG0569	domain protein
AUMI_RS07515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUMI_RS07545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AUMI_RS07550	COG0017	Asparaginyl-tRNA synthetase
AUMI_RS07555	COG0406	alpha-ribazole phosphatase activity
AUMI_RS07560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AUMI_RS07565	COG0785	Cytochrome C biogenesis protein
AUMI_RS07570	COG1333	cytochrome c biogenesis protein
AUMI_RS07575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AUMI_RS07580	COG4948	Mandelate Racemase Muconate Lactonizing
AUMI_RS07585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUMI_RS07610	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUMI_RS07615	COG1169	isochorismate synthase
AUMI_RS07620	COG2226	methyltransferase
AUMI_RS07625	COG0142	geranyltranstransferase activity
AUMI_RS07640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AUMI_RS07645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUMI_RS07650	COG0730	response to heat
AUMI_RS07660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUMI_RS07670	COG0531	amino acid
AUMI_RS07675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AUMI_RS07685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUMI_RS07690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUMI_RS07700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUMI_RS07705	COG0697	spore germination
AUMI_RS07710	COG1605	Chorismate mutase
AUMI_RS07710	COG0287	Prephenate dehydrogenase
AUMI_RS07720	COG0656	L-ascorbic acid biosynthetic process
AUMI_RS07725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUMI_RS07735	COG0047	phosphoribosylformylglycinamidine synthase activity
AUMI_RS07740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUMI_RS07755	COG3483	tryptophan 2,3-dioxygenase activity
AUMI_RS07760	COG2608	mercury ion transmembrane transporter activity
AUMI_RS07770	COG2364	Membrane
AUMI_RS07775	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUMI_RS07780	COG0151	Belongs to the GarS family
AUMI_RS07790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AUMI_RS07800	COG0640	Transcriptional regulator
AUMI_RS07810	COG0745	RESPONSE REGULATOR receiver
AUMI_RS07840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUMI_RS07850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AUMI_RS07855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AUMI_RS07865	COG2272	Belongs to the type-B carboxylesterase lipase family
AUMI_RS07870	COG1666	GTP binding
AUMI_RS07890	COG2409	Drug exporters of the RND superfamily
AUMI_RS07895	COG2838	Isocitrate dehydrogenase
AUMI_RS07920	COG0741	lytic transglycosylase activity
AUMI_RS07920	COG0739	heme binding
AUMI_RS07920	COG1196	nuclear chromosome segregation
AUMI_RS07925	COG0366	Alpha amylase catalytic
AUMI_RS07940	COG0387	Pfam Sodium calcium exchanger
AUMI_RS07965	COG0584	glycerophosphoryl diester phosphodiesterase
AUMI_RS07980	COG0045	succinate-CoA ligase (ADP-forming) activity
AUMI_RS08005	COG0138	bifunctional purine biosynthesis protein purh
AUMI_RS08010	COG1834	amidinotransferase
AUMI_RS08025	COG2301	Belongs to the HpcH HpaI aldolase family
AUMI_RS08040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AUMI_RS08050	COG1802	Transcriptional regulator
AUMI_RS08065	COG0519	Catalyzes the synthesis of GMP from XMP
AUMI_RS08065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AUMI_RS08080	COG1012	belongs to the aldehyde dehydrogenase family