locus-tag	class	description
Q31a_RS00040	COG0577	efflux transmembrane transporter activity
Q31a_RS00045	COG1136	(ABC) transporter
Q31a_RS00065	COG1643	Atp-dependent helicase
Q31a_RS00095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q31a_RS00105	COG0515	serine threonine protein kinase
Q31a_RS00125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q31a_RS00130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS00140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Q31a_RS00145	COG0668	transmembrane transport
Q31a_RS00155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS00180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Q31a_RS00195	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Q31a_RS00210	COG0736	holo-[acyl-carrier-protein] synthase activity
Q31a_RS00215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Q31a_RS00220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Q31a_RS00270	COG0515	serine threonine protein kinase
Q31a_RS00270	COG2815	serine threonine protein kinase
Q31a_RS00280	COG1216	Glycosyl transferase, family 2
Q31a_RS00280	COG1442	glycosyl transferase family 8
Q31a_RS00285	COG0644	oxidoreductase
Q31a_RS00320	COG0348	domain, Protein
Q31a_RS00325	COG2010	Cytochrome c
Q31a_RS00340	COG3119	arylsulfatase activity
Q31a_RS00370	COG0330	HflC and HflK could
Q31a_RS00390	COG1381	Involved in DNA repair and RecF pathway recombination
Q31a_RS00395	COG0745	RESPONSE REGULATOR receiver
Q31a_RS00400	COG0521	Mo-molybdopterin cofactor biosynthetic process
Q31a_RS00405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS00410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Q31a_RS00460	COG0443	Heat shock 70 kDa protein
Q31a_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS00505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Q31a_RS00510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS00535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_RS00550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_RS00570	COG0714	Associated with various cellular activities
Q31a_RS00590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_RS00595	COG3118	belongs to the thioredoxin family
Q31a_RS00610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Q31a_RS00620	COG2738	Putative neutral zinc metallopeptidase
Q31a_RS00625	COG1595	DNA-templated transcription, initiation
Q31a_RS00635	COG2815	serine threonine protein kinase
Q31a_RS00635	COG0515	serine threonine protein kinase
Q31a_RS00655	COG0588	phosphoglycerate mutase activity
Q31a_RS00665	COG2610	gluconate transmembrane transporter activity
Q31a_RS00670	COG0114	fumarate hydratase activity
Q31a_RS00675	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_RS00695	COG3119	arylsulfatase activity
Q31a_RS00695	COG3408	Glycogen debranching enzyme
Q31a_RS00705	COG2815	serine threonine protein kinase
Q31a_RS00705	COG0515	serine threonine protein kinase
Q31a_RS00710	COG1595	DNA-templated transcription, initiation
Q31a_RS00720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Q31a_RS00740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Q31a_RS00745	COG2076	Multidrug Resistance protein
Q31a_RS00795	COG0463	Glycosyl transferase, family 2
Q31a_RS00800	COG3263	regulation of cellular component size
Q31a_RS00855	COG2755	lipolytic protein G-D-S-L family
Q31a_RS00865	COG3119	arylsulfatase activity
Q31a_RS00870	COG3119	arylsulfatase activity
Q31a_RS00895	COG2755	lipolytic protein G-D-S-L family
Q31a_RS00895	COG0657	acetylesterase activity
Q31a_RS00960	COG2204	response regulator
Q31a_RS00965	COG0328	RNA-DNA hybrid ribonuclease activity
Q31a_RS00970	COG0626	cystathionine gamma-synthase activity
Q31a_RS00975	COG0626	cystathionine gamma-synthase activity
Q31a_RS01025	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Q31a_RS01035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_RS01045	COG1716	ATPase activity
Q31a_RS01055	COG2154	pterin-4-alpha-carbinolamine dehydratase
Q31a_RS01060	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Q31a_RS01070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Q31a_RS01075	COG0569	domain protein
Q31a_RS01075	COG0189	ligase activity
Q31a_RS01100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q31a_RS01115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Q31a_RS01120	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q31a_RS01125	COG1121	(ABC) transporter
Q31a_RS01130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q31a_RS01130	COG1321	iron dependent repressor
Q31a_RS01155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Q31a_RS01180	COG3973	AAA domain
Q31a_RS01190	COG0534	Mate efflux family protein
Q31a_RS01200	COG0515	serine threonine protein kinase
Q31a_RS01205	COG0463	Glycosyl transferase, family 2
Q31a_RS01245	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Q31a_RS01255	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Q31a_RS01265	COG4869	propanediol catabolic process
Q31a_RS01285	COG3119	arylsulfatase activity
Q31a_RS01310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q31a_RS01315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS01350	COG0714	Associated with various cellular activities
Q31a_RS01355	COG2081	HI0933 family
Q31a_RS01360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_RS01370	COG0501	Belongs to the peptidase M48B family
Q31a_RS01375	COG1704	LemA family
Q31a_RS01385	COG3119	arylsulfatase activity
Q31a_RS01400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q31a_RS01430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q31a_RS01445	COG3850	Histidine kinase
Q31a_RS01445	COG3437	response regulator, receiver
Q31a_RS01445	COG2205	protein histidine kinase activity
Q31a_RS01445	COG4999	Histidine kinase
Q31a_RS01455	COG4771	TonB-dependent receptor
Q31a_RS01460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_RS01465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Q31a_RS01510	COG1215	transferase activity, transferring glycosyl groups
Q31a_RS01515	COG1305	Transglutaminase-like
Q31a_RS01535	COG0277	FAD linked oxidase domain protein
Q31a_RS01575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Q31a_RS01595	COG3119	arylsulfatase activity
Q31a_RS01630	COG0569	domain protein
Q31a_RS01730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q31a_RS01745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q31a_RS01745	COG2813	Specifically methylates the guanine in position
Q31a_RS01760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_RS01765	COG0577	efflux transmembrane transporter activity
Q31a_RS01765	COG1136	(ABC) transporter
Q31a_RS01770	COG1136	(ABC) transporter
Q31a_RS01820	COG0859	PFAM glycosyl transferase family 9
Q31a_RS01825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q31a_RS01835	COG3119	arylsulfatase activity
Q31a_RS01840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Q31a_RS01845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q31a_RS01850	COG2346	COG2346, Truncated hemoglobins
Q31a_RS01855	COG0004	ammonium transporteR
Q31a_RS01860	COG4912	Dna alkylation repair
Q31a_RS01875	COG4447	cellulose binding
Q31a_RS01880	COG0569	domain protein
Q31a_RS01880	COG0189	ligase activity
Q31a_RS01890	COG2308	Evidence 4 Homologs of previously reported genes of
Q31a_RS01910	COG2308	Evidence 4 Homologs of previously reported genes of
Q31a_RS01910	COG2307	Protein conserved in bacteria
Q31a_RS01915	COG1305	Transglutaminase-like
Q31a_RS01930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Q31a_RS01930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Q31a_RS01965	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Q31a_RS02020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q31a_RS02035	COG2890	protein-(glutamine-N5) methyltransferase activity
Q31a_RS02045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q31a_RS02045	COG0758	DNA mediated transformation
Q31a_RS02050	COG1199	ATP-dependent helicase activity
Q31a_RS02055	COG2818	Glycosylase
Q31a_RS02060	COG0515	serine threonine protein kinase
Q31a_RS02060	COG2815	serine threonine protein kinase
Q31a_RS02070	COG2755	lipolytic protein G-D-S-L family
Q31a_RS02070	COG0657	acetylesterase activity
Q31a_RS02090	COG0187	DNA topoisomerase II activity
Q31a_RS02115	COG1229	Formylmethanofuran dehydrogenase subunit A
Q31a_RS02120	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Q31a_RS02140	COG2226	methyltransferase
Q31a_RS02160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q31a_RS02165	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Q31a_RS02185	COG0515	serine threonine protein kinase
Q31a_RS02185	COG2815	serine threonine protein kinase
Q31a_RS02210	COG2815	serine threonine protein kinase
Q31a_RS02210	COG0515	serine threonine protein kinase
Q31a_RS02215	COG0242	peptide deformylase activity
Q31a_RS02220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Q31a_RS02225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Q31a_RS02235	COG2957	Belongs to the agmatine deiminase family
Q31a_RS02255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Q31a_RS02260	COG1131	(ABC) transporter
Q31a_RS02270	COG0432	Pfam Uncharacterised protein family UPF0047
Q31a_RS02275	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Q31a_RS02395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS02485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS02565	COG4974	Belongs to the 'phage' integrase family
Q31a_RS02585	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Q31a_RS02590	COG0529	Catalyzes the synthesis of activated sulfate
Q31a_RS02590	COG2895	sulfate adenylyltransferase (ATP) activity
Q31a_RS02595	COG0175	sulfate reduction
Q31a_RS02600	COG0357	Ribosomal RNA small subunit methyltransferase G
Q31a_RS02610	COG4232	protein-disulfide reductase activity
Q31a_RS02615	COG2813	Specifically methylates the guanine in position
Q31a_RS02625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_RS02635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_RS02660	COG0367	asparagine synthase
Q31a_RS02665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q31a_RS02690	COG0793	Belongs to the peptidase S41A family
Q31a_RS02700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q31a_RS02725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q31a_RS02725	COG1845	cytochrome c oxidase, subunit III
Q31a_RS02730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q31a_RS02760	COG0437	4 iron, 4 sulfur cluster binding
Q31a_RS02790	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_RS02815	COG2353	YceI-like domain
Q31a_RS02870	COG0515	serine threonine protein kinase
Q31a_RS02870	COG3266	domain, Protein
Q31a_RS02890	COG3408	Glycogen debranching enzyme
Q31a_RS02890	COG3119	arylsulfatase activity
Q31a_RS02915	COG3100	YcgL domain-containing protein
Q31a_RS02915	COG0561	phosphatase activity
Q31a_RS02935	COG0657	acetylesterase activity
Q31a_RS02940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q31a_RS02940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q31a_RS02970	COG0714	Associated with various cellular activities
Q31a_RS02980	COG0488	(ABC) transporter
Q31a_RS03005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_RS03025	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Q31a_RS03065	COG0587	DNA-directed DNA polymerase activity
Q31a_RS03120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_RS03125	COG0673	inositol 2-dehydrogenase activity
Q31a_RS03160	COG4651	solute:proton antiporter activity
Q31a_RS03160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Q31a_RS03165	COG3119	arylsulfatase activity
Q31a_RS03225	COG1192	Involved in chromosome partitioning
Q31a_RS03240	COG1045	serine acetyltransferase
Q31a_RS03270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q31a_RS03275	COG0602	queuosine metabolic process
Q31a_RS03305	COG0066	3-isopropylmalate dehydratase activity
Q31a_RS03310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Q31a_RS03320	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Q31a_RS03350	COG0673	inositol 2-dehydrogenase activity
Q31a_RS03360	COG0714	Associated with various cellular activities
Q31a_RS03375	COG0667	Aldo Keto reductase
Q31a_RS03390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q31a_RS03395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Q31a_RS03430	COG0577	efflux transmembrane transporter activity
Q31a_RS03430	COG1136	(ABC) transporter
Q31a_RS03435	COG1136	(ABC) transporter
Q31a_RS03460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q31a_RS03465	COG0459	protein refolding
Q31a_RS03475	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Q31a_RS03530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q31a_RS03590	COG3875	lactate racemase activity
Q31a_RS03595	COG1620	l-lactate permease
Q31a_RS03600	COG3119	arylsulfatase activity
Q31a_RS03605	COG3119	arylsulfatase activity
Q31a_RS03620	COG0714	Associated with various cellular activities
Q31a_RS03690	COG1609	Transcriptional regulator
Q31a_RS03705	COG2815	serine threonine protein kinase
Q31a_RS03705	COG0515	serine threonine protein kinase
Q31a_RS03730	COG3119	arylsulfatase activity
Q31a_RS03755	COG3119	arylsulfatase activity
Q31a_RS03845	COG3119	arylsulfatase activity
Q31a_RS03850	COG3119	arylsulfatase activity
Q31a_RS03860	COG1819	glycosyl
Q31a_RS03910	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Q31a_RS03945	COG2815	serine threonine protein kinase
Q31a_RS03945	COG0515	serine threonine protein kinase
Q31a_RS03950	COG1595	DNA-templated transcription, initiation
Q31a_RS03975	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Q31a_RS03980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q31a_RS03985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Q31a_RS03995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q31a_RS04010	COG0129	dihydroxy-acid dehydratase activity
Q31a_RS04025	COG0163	prenyltransferase activity
Q31a_RS04030	COG2226	methyltransferase
Q31a_RS04035	COG1556	Lactate utilization protein
Q31a_RS04040	COG1253	flavin adenine dinucleotide binding
Q31a_RS04055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_RS04060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q31a_RS04065	COG0577	efflux transmembrane transporter activity
Q31a_RS04065	COG1136	(ABC) transporter
Q31a_RS04085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q31a_RS04090	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Q31a_RS04120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Q31a_RS04135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Q31a_RS04140	COG0203	ribosomal protein L17
Q31a_RS04145	COG0202	RNA polymerase activity
Q31a_RS04150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Q31a_RS04155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Q31a_RS04165	COG0201	protein transport
Q31a_RS04170	COG0200	Binds to the 23S rRNA
Q31a_RS04175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Q31a_RS04180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Q31a_RS04185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Q31a_RS04190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Q31a_RS04195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Q31a_RS04200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Q31a_RS04205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Q31a_RS04210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Q31a_RS04215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Q31a_RS04220	COG0255	Belongs to the universal ribosomal protein uL29 family
Q31a_RS04225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Q31a_RS04230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Q31a_RS04235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Q31a_RS04240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Q31a_RS04245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Q31a_RS04250	COG0089	rRNA binding
Q31a_RS04255	COG0088	Forms part of the polypeptide exit tunnel
Q31a_RS04260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Q31a_RS04265	COG0051	transcription antitermination factor activity, RNA binding
Q31a_RS04285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Q31a_RS04295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS04305	COG0107	imidazoleglycerol-phosphate synthase activity
Q31a_RS04315	COG2885	chlorophyll binding
Q31a_RS04330	COG0811	peptide transport
Q31a_RS04340	COG0180	Tryptophanyl-tRNA synthetase
Q31a_RS04365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q31a_RS04370	COG1758	RNA polymerase activity
Q31a_RS04375	COG0194	GDP metabolic process
Q31a_RS04380	COG1561	YicC-like family, N-terminal region
Q31a_RS04390	COG0149	triose-phosphate isomerase activity
Q31a_RS04405	COG3119	arylsulfatase activity
Q31a_RS04410	COG3008	intermembrane lipid transfer
Q31a_RS04415	COG2995	paraquat-inducible protein a
Q31a_RS04425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Q31a_RS04440	COG0156	8-amino-7-oxononanoate synthase activity
Q31a_RS04505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS04505	COG3320	Male sterility
Q31a_RS04515	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Q31a_RS04515	COG3264	Mechanosensitive ion channel
Q31a_RS04575	COG2384	SAM-dependent methyltransferase
Q31a_RS04595	COG0204	Acyl-transferase
Q31a_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_RS04600	COG3119	arylsulfatase activity
Q31a_RS04615	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Q31a_RS04625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Q31a_RS04640	COG1136	(ABC) transporter
Q31a_RS04640	COG0577	efflux transmembrane transporter activity
Q31a_RS04645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Q31a_RS04695	COG3119	arylsulfatase activity
Q31a_RS04700	COG3830	Belongs to the UPF0237 family
Q31a_RS04700	COG0560	Phosphoserine phosphatase
Q31a_RS04705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Q31a_RS04715	COG1872	DUF167
Q31a_RS04720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Q31a_RS04745	COG4650	regulator
Q31a_RS04755	COG0430	RNA-3'-phosphate cyclase activity
Q31a_RS04775	COG0024	Methionine aminopeptidase
Q31a_RS04780	COG1671	Belongs to the UPF0178 family
Q31a_RS04785	COG0513	Belongs to the DEAD box helicase family
Q31a_RS04790	COG1278	Cold shock
Q31a_RS04815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q31a_RS04835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Q31a_RS04840	COG0081	regulation of translation
Q31a_RS04845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Q31a_RS04850	COG0222	ribosome binding
Q31a_RS04855	COG0248	Ppx GppA phosphatase
Q31a_RS04875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Q31a_RS04915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_RS04930	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Q31a_RS04940	COG1970	mechanosensitive ion channel activity
Q31a_RS04945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Q31a_RS04950	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q31a_RS04980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Q31a_RS04995	COG0556	nucleotide-excision repair
Q31a_RS05000	COG0515	serine threonine protein kinase
Q31a_RS05000	COG2815	serine threonine protein kinase
Q31a_RS05010	COG0564	pseudouridine synthase activity
Q31a_RS05065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Q31a_RS05070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q31a_RS05080	COG0724	RNA recognition motif
Q31a_RS05120	COG0537	adenosine 5'-monophosphoramidase activity
Q31a_RS05145	COG0564	pseudouridine synthase activity
Q31a_RS05150	COG1966	Carbon starvation protein
Q31a_RS05155	COG1301	dicarboxylic acid transport
Q31a_RS05170	COG1450	Type ii and iii secretion system protein
Q31a_RS05190	COG4999	Histidine kinase
Q31a_RS05190	COG2205	protein histidine kinase activity
Q31a_RS05190	COG3850	Histidine kinase
Q31a_RS05190	COG3437	response regulator, receiver
Q31a_RS05215	COG3119	arylsulfatase activity
Q31a_RS05220	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS05245	COG0006	proline dipeptidase activity
Q31a_RS05250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q31a_RS05250	COG0519	Catalyzes the synthesis of GMP from XMP
Q31a_RS05255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS05285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Q31a_RS05295	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Q31a_RS05305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Q31a_RS05310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q31a_RS05475	COG4974	Belongs to the 'phage' integrase family
Q31a_RS05650	COG2186	Transcriptional regulator
Q31a_RS05655	COG4221	oxidoreductase activity
Q31a_RS05685	COG0653	protein targeting
Q31a_RS05690	COG1519	Transferase
Q31a_RS05695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Q31a_RS05700	COG0085	RNA polymerase activity
Q31a_RS05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS05715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS05720	COG1459	type II secretion system
Q31a_RS05765	COG0205	6-phosphofructokinase activity
Q31a_RS05770	COG0439	Biotin carboxylase
Q31a_RS05775	COG0511	ligase activity, forming carbon-carbon bonds
Q31a_RS05780	COG0006	proline dipeptidase activity
Q31a_RS05810	COG1754	DNA topoisomerase type I activity
Q31a_RS05810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q31a_RS05830	COG0297	glycogen (starch) synthase activity
Q31a_RS05875	COG4970	Tfp pilus assembly protein FimT
Q31a_RS05885	COG1459	type II secretion system
Q31a_RS05890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS05935	COG3119	arylsulfatase activity
Q31a_RS05940	COG3119	arylsulfatase activity
Q31a_RS05985	COG0488	(ABC) transporter
Q31a_RS06010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q31a_RS06020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Q31a_RS06030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q31a_RS06045	COG0300	oxidoreductase activity
Q31a_RS06085	COG0488	(ABC) transporter
Q31a_RS06090	COG3089	Belongs to the UPF0270 family
Q31a_RS06150	COG0247	lactate metabolic process
Q31a_RS06160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q31a_RS06165	COG0049	tRNA binding
Q31a_RS06170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Q31a_RS06180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Q31a_RS06190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_RS06195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS06200	COG0358	DNA primase activity
Q31a_RS06205	COG1227	inorganic diphosphatase activity
Q31a_RS06205	COG0517	IMP dehydrogenase activity
Q31a_RS06215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Q31a_RS06285	COG1621	beta-fructofuranosidase activity
Q31a_RS06290	COG0589	response to stress
Q31a_RS06295	COG0589	response to stress
Q31a_RS06300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_RS06305	COG0471	metal ion transport
Q31a_RS06305	COG0490	domain, Protein
Q31a_RS06315	COG4974	Belongs to the 'phage' integrase family
Q31a_RS06375	COG3415	Transposase
Q31a_RS06375	COG2801	Transposase and inactivated derivatives
Q31a_RS06390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS06415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS06435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Q31a_RS06440	COG2197	response regulator
Q31a_RS06455	COG3119	arylsulfatase activity
Q31a_RS06480	COG1160	GTP binding
Q31a_RS06525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Q31a_RS06530	COG1185	polyribonucleotide nucleotidyltransferase activity
Q31a_RS06550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q31a_RS06555	COG0515	serine threonine protein kinase
Q31a_RS06555	COG2815	serine threonine protein kinase
Q31a_RS06560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Q31a_RS06585	COG1285	pathogenesis
Q31a_RS06590	COG3237	CsbD-like
Q31a_RS06600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q31a_RS06605	COG1449	Belongs to the glycosyl hydrolase 57 family
Q31a_RS06615	COG4993	Dehydrogenase
Q31a_RS06635	COG1404	Belongs to the peptidase S8 family
Q31a_RS06640	COG3437	response regulator, receiver
Q31a_RS06640	COG2205	protein histidine kinase activity
Q31a_RS06640	COG3850	Histidine kinase
Q31a_RS06640	COG4999	Histidine kinase
Q31a_RS06655	COG3119	arylsulfatase activity
Q31a_RS06665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Q31a_RS06670	COG0823	Involved in the tonB-independent uptake of proteins
Q31a_RS06670	COG1506	peptidase
Q31a_RS06675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q31a_RS06755	COG2815	serine threonine protein kinase
Q31a_RS06755	COG0515	serine threonine protein kinase
Q31a_RS06845	COG0714	Associated with various cellular activities
Q31a_RS06930	COG0515	serine threonine protein kinase
Q31a_RS06930	COG2815	serine threonine protein kinase
Q31a_RS06950	COG0515	serine threonine protein kinase
Q31a_RS06950	COG2815	serine threonine protein kinase
Q31a_RS06970	COG3119	arylsulfatase activity
Q31a_RS06995	COG2204	response regulator
Q31a_RS07000	COG4191	Histidine kinase
Q31a_RS07005	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_RS07020	COG0668	transmembrane transport
Q31a_RS07045	COG3119	arylsulfatase activity
Q31a_RS07055	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Q31a_RS07060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS07070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_RS07095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_RS07105	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS07110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q31a_RS07120	COG3119	arylsulfatase activity
Q31a_RS07150	COG3119	arylsulfatase activity
Q31a_RS07180	COG1725	Transcriptional regulator
Q31a_RS07185	COG1131	(ABC) transporter
Q31a_RS07195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q31a_RS07200	COG1774	PSP1 C-terminal conserved region
Q31a_RS07220	COG2211	Major facilitator Superfamily
Q31a_RS07245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q31a_RS07250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q31a_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS07255	COG3321	synthase
Q31a_RS07255	COG0604	alcohol dehydrogenase
Q31a_RS07270	COG0129	dihydroxy-acid dehydratase activity
Q31a_RS07305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q31a_RS07310	COG0322	excinuclease ABC activity
Q31a_RS07350	COG2706	6-phosphogluconolactonase activity
Q31a_RS07360	COG3119	arylsulfatase activity
Q31a_RS07365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_RS07370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_RS07400	COG0505	Belongs to the CarA family
Q31a_RS07405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Q31a_RS07410	COG3119	arylsulfatase activity
Q31a_RS07420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Q31a_RS07460	COG0750	zinc metalloprotease
Q31a_RS07465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Q31a_RS07470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_RS07480	COG0515	serine threonine protein kinase
Q31a_RS07480	COG2815	serine threonine protein kinase
Q31a_RS07490	COG5549	protein import
Q31a_RS07490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS07520	COG1937	Protein conserved in bacteria
Q31a_RS07535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_RS07555	COG1595	DNA-templated transcription, initiation
Q31a_RS07615	COG4806	L-rhamnose isomerase
Q31a_RS07730	COG3437	response regulator, receiver
Q31a_RS07730	COG2770	Histidine kinase
Q31a_RS07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_RS07765	COG0463	Glycosyl transferase, family 2
Q31a_RS07770	COG2226	methyltransferase
Q31a_RS07785	COG0306	phosphate transporter
Q31a_RS07790	COG1216	Glycosyl transferase, family 2
Q31a_RS07805	COG0640	Transcriptional regulator
Q31a_RS07830	COG3795	YCII-related domain
Q31a_RS07840	COG3795	YCII-related domain
Q31a_RS08010	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Q31a_RS08025	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS08035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_RS08055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS08065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Q31a_RS08105	COG1063	alcohol dehydrogenase
Q31a_RS08110	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_RS08120	COG1132	(ABC) transporter
Q31a_RS08130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_RS08165	COG0500	methyltransferase
Q31a_RS08180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_RS08180	COG1522	sequence-specific DNA binding
Q31a_RS08185	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS08205	COG0667	Aldo Keto reductase
Q31a_RS08220	COG0347	Belongs to the P(II) protein family
Q31a_RS08255	COG1858	cytochrome C peroxidase
Q31a_RS08285	COG3119	arylsulfatase activity
Q31a_RS08300	COG3119	arylsulfatase activity
Q31a_RS08325	COG3119	arylsulfatase activity
Q31a_RS08350	COG0463	Glycosyl transferase, family 2
Q31a_RS08390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_RS08390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_RS08395	COG3142	Participates in the control of copper homeostasis
Q31a_RS08400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Q31a_RS08410	COG2321	neutral zinc metallopeptidase
Q31a_RS08420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Q31a_RS08425	COG2084	Dehydrogenase
Q31a_RS08445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS08450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS08450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS08465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS08685	COG0457	Tetratricopeptide repeat
Q31a_RS08685	COG0515	serine threonine protein kinase
Q31a_RS08690	COG2094	Belongs to the DNA glycosylase MPG family
Q31a_RS08705	COG1573	uracil-dna glycosylase
Q31a_RS08710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q31a_RS08790	COG0045	succinate-CoA ligase (ADP-forming) activity
Q31a_RS08790	COG1042	CoA-binding domain protein
Q31a_RS08790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q31a_RS08805	COG0588	phosphoglycerate mutase activity
Q31a_RS08845	COG3250	beta-galactosidase activity
Q31a_RS08880	COG2226	methyltransferase
Q31a_RS08915	COG0673	inositol 2-dehydrogenase activity
Q31a_RS08930	COG1064	alcohol dehydrogenase
Q31a_RS08965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q31a_RS08980	COG0528	UMP kinase activity
Q31a_RS08985	COG0233	cytoplasmic translational termination
Q31a_RS09000	COG1994	Peptidase M50
Q31a_RS09000	COG0517	IMP dehydrogenase activity
Q31a_RS09010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q31a_RS09035	COG0436	Aminotransferase
Q31a_RS09045	COG1137	ATPase activity
Q31a_RS09050	COG0515	serine threonine protein kinase
Q31a_RS09050	COG2815	serine threonine protein kinase
Q31a_RS09060	COG2200	EAL domain
Q31a_RS09060	COG2771	luxR family
Q31a_RS09215	COG3119	arylsulfatase activity
Q31a_RS09270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Q31a_RS09280	COG0826	peptidase U32
Q31a_RS09320	COG2022	thiamine diphosphate biosynthetic process
Q31a_RS09345	COG1643	Atp-dependent helicase
Q31a_RS09355	COG0321	lipoyl(octanoyl) transferase activity
Q31a_RS09355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Q31a_RS09360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q31a_RS09360	COG0617	tRNA 3'-terminal CCA addition
Q31a_RS09360	COG0517	IMP dehydrogenase activity
Q31a_RS09375	COG3540	Alkaline phosphatase
Q31a_RS09380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Q31a_RS09410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_RS09415	COG1335	isochorismatase
Q31a_RS09425	COG1091	dTDP-4-dehydrorhamnose reductase activity
Q31a_RS09430	COG2382	esterase
Q31a_RS09445	COG1040	competence protein
Q31a_RS09505	COG2942	2-epimerase
Q31a_RS09510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Q31a_RS09515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Q31a_RS09555	COG0047	phosphoribosylformylglycinamidine synthase activity
Q31a_RS09570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Q31a_RS09575	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q31a_RS09605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS09630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Q31a_RS09640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q31a_RS09645	COG1509	lysine 2,3-aminomutase activity
Q31a_RS09650	COG0285	dihydrofolate synthase activity
Q31a_RS09655	COG1131	(ABC) transporter
Q31a_RS09685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_RS09730	COG0473	3-isopropylmalate dehydrogenase activity
Q31a_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS09945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q31a_RS09950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Q31a_RS09960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Q31a_RS09970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Q31a_RS09980	COG0134	indole-3-glycerol-phosphate synthase activity
Q31a_RS09985	COG0138	bifunctional purine biosynthesis protein purh
Q31a_RS09990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Q31a_RS10000	COG1131	(ABC) transporter
Q31a_RS10035	COG0142	geranyltranstransferase activity
Q31a_RS10055	COG3119	arylsulfatase activity
Q31a_RS10060	COG4948	Mandelate Racemase Muconate Lactonizing
Q31a_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS10110	COG0714	Associated with various cellular activities
Q31a_RS10115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Q31a_RS10120	COG0017	Asparaginyl-tRNA synthetase
Q31a_RS10125	COG0492	ferredoxin-NADP+ reductase activity
Q31a_RS10130	COG0471	metal ion transport
Q31a_RS10160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Q31a_RS10170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Q31a_RS10225	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Q31a_RS10245	COG0084	hydrolase, TatD family'
Q31a_RS10250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q31a_RS10260	COG1448	Aminotransferase
Q31a_RS10265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_RS10265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_RS10295	COG0037	tRNA processing
Q31a_RS10305	COG0343	queuine tRNA-ribosyltransferase activity
Q31a_RS10310	COG0202	RNA polymerase activity
Q31a_RS10325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_RS10365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS10375	COG0247	lactate metabolic process
Q31a_RS10395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_RS10405	COG1070	Carbohydrate kinase
Q31a_RS10415	COG0135	phosphoribosylanthranilate isomerase activity
Q31a_RS10445	COG4067	protein conserved in archaea
Q31a_RS10445	COG0189	ligase activity
Q31a_RS10450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Q31a_RS10460	COG0730	response to heat
Q31a_RS10465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_RS10470	COG1678	Uncharacterized ACR, COG1678
Q31a_RS10480	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_RS10485	COG0673	inositol 2-dehydrogenase activity
Q31a_RS10495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Q31a_RS10500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_RS10510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Q31a_RS10530	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Q31a_RS10550	COG0784	Response regulator, receiver
Q31a_RS10550	COG0643	Histidine kinase
Q31a_RS10550	COG2198	Histidine kinase
Q31a_RS10555	COG0835	chemotaxis
Q31a_RS10560	COG2201	protein-glutamate methylesterase activity
Q31a_RS10570	COG1475	DNA binding
Q31a_RS10575	COG1192	Involved in chromosome partitioning
Q31a_RS10605	COG0488	(ABC) transporter
Q31a_RS10635	COG0322	excinuclease ABC activity
Q31a_RS10685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Q31a_RS10705	COG1139	Iron-sulfur cluster binding protein
Q31a_RS10710	COG0018	arginyl-trna synthetase
Q31a_RS10715	COG0799	negative regulation of ribosome biogenesis
Q31a_RS10720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q31a_RS10730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Q31a_RS10780	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Q31a_RS10790	COG1408	metallophosphoesterase
Q31a_RS10820	COG2815	serine threonine protein kinase
Q31a_RS10820	COG0515	serine threonine protein kinase
Q31a_RS10830	COG0076	glutamate decarboxylase activity
Q31a_RS10845	COG2755	lipolytic protein G-D-S-L family
Q31a_RS10845	COG0657	acetylesterase activity
Q31a_RS10855	COG1058	Belongs to the CinA family
Q31a_RS10855	COG1546	Belongs to the CinA family
Q31a_RS10870	COG1136	(ABC) transporter
Q31a_RS10870	COG0577	efflux transmembrane transporter activity
Q31a_RS10875	COG0577	efflux transmembrane transporter activity
Q31a_RS10900	COG0545	Peptidyl-prolyl cis-trans isomerase
Q31a_RS10935	COG0529	Catalyzes the synthesis of activated sulfate
Q31a_RS10955	COG1530	ribonuclease E activity
Q31a_RS10970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q31a_RS10985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q31a_RS11020	COG1070	Carbohydrate kinase
Q31a_RS11025	COG2205	protein histidine kinase activity
Q31a_RS11035	COG4864	UPF0365 protein
Q31a_RS11045	COG2326	polyphosphate kinase activity
Q31a_RS11055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS11055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS11065	COG1131	(ABC) transporter
Q31a_RS11075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_RS11085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS11115	COG0673	inositol 2-dehydrogenase activity
Q31a_RS11140	COG1692	metallophosphoesterase
Q31a_RS11145	COG1418	mRNA catabolic process
Q31a_RS11165	COG1511	domain protein
Q31a_RS11165	COG3264	Mechanosensitive ion channel
Q31a_RS11170	COG0598	Magnesium transport protein CorA
Q31a_RS11195	COG4251	negative regulation of phosphorylation
Q31a_RS11200	COG0784	Response regulator, receiver
Q31a_RS11205	COG0517	IMP dehydrogenase activity
Q31a_RS11205	COG0516	GMP reductase activity
Q31a_RS11230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q31a_RS11240	COG1131	(ABC) transporter
Q31a_RS11255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q31a_RS11280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_RS11285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS11290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_RS11295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q31a_RS11300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q31a_RS11305	COG0483	inositol monophosphate 1-phosphatase activity
Q31a_RS11310	COG0656	L-ascorbic acid biosynthetic process
Q31a_RS11390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_RS11415	COG3119	arylsulfatase activity
Q31a_RS11465	COG3119	arylsulfatase activity
Q31a_RS11485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS11495	COG1566	PFAM secretion protein HlyD family protein
Q31a_RS11520	COG2909	trisaccharide binding
Q31a_RS11540	COG0515	serine threonine protein kinase
Q31a_RS11540	COG2815	serine threonine protein kinase
Q31a_RS11560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q31a_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS11575	COG2814	Major facilitator Superfamily
Q31a_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q31a_RS11595	COG0512	Glutamine amidotransferase of anthranilate synthase
Q31a_RS11600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q31a_RS11610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS11615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Q31a_RS11630	COG1331	Highly conserved protein containing a thioredoxin domain
Q31a_RS11635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Q31a_RS11645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q31a_RS11655	COG1595	DNA-templated transcription, initiation
Q31a_RS11665	COG2373	Large extracellular alpha-helical protein
Q31a_RS11690	COG3781	membrane
Q31a_RS11715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS11720	COG1104	cysteine desulfurase activity
Q31a_RS11725	COG0628	permease
Q31a_RS11735	COG3119	arylsulfatase activity
Q31a_RS11740	COG0840	transmembrane signaling receptor activity
Q31a_RS11765	COG0657	acetylesterase activity
Q31a_RS11770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Q31a_RS11775	COG0052	Belongs to the universal ribosomal protein uS2 family
Q31a_RS11815	COG0009	L-threonylcarbamoyladenylate synthase
Q31a_RS11820	COG0237	dephospho-CoA kinase activity
Q31a_RS11830	COG1902	pentaerythritol trinitrate reductase activity
Q31a_RS11860	COG0573	inorganic phosphate transmembrane transporter activity
Q31a_RS11865	COG0581	inorganic phosphate transmembrane transporter activity
Q31a_RS11870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q31a_RS11875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q31a_RS11905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_RS11960	COG2936	dipeptidyl-peptidase activity
Q31a_RS11975	COG2304	oxidoreductase activity
Q31a_RS11980	COG2304	oxidoreductase activity
Q31a_RS11995	COG0714	Associated with various cellular activities
Q31a_RS12005	COG1505	serine-type exopeptidase activity
Q31a_RS12020	COG0328	RNA-DNA hybrid ribonuclease activity
Q31a_RS12025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q31a_RS12035	COG2382	esterase
Q31a_RS12045	COG4980	gas vesicle protein
Q31a_RS12045	COG1674	ftsk spoiiie
Q31a_RS12050	COG4589	Belongs to the CDS family
Q31a_RS12060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_RS12125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q31a_RS12135	COG0527	aspartate kinase activity
Q31a_RS12140	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Q31a_RS12185	COG0714	Associated with various cellular activities
Q31a_RS12230	COG0495	leucyl-tRNA aminoacylation
Q31a_RS12235	COG1216	Glycosyl transferase, family 2
Q31a_RS12240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q31a_RS12255	COG0494	nUDIX hydrolase
Q31a_RS12280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Q31a_RS12295	COG1621	beta-fructofuranosidase activity
Q31a_RS12425	COG4695	Portal protein
Q31a_RS12430	COG1802	Transcriptional regulator
Q31a_RS12430	COG4626	Terminase
Q31a_RS12500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS12535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS12550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS12565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Q31a_RS12565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q31a_RS12585	COG4566	intracellular signal transduction
Q31a_RS12595	COG2183	response to ionizing radiation
Q31a_RS12595	COG0539	negative regulation of cytoplasmic translation
Q31a_RS12600	COG0698	ribose 5-phosphate isomerase
Q31a_RS12605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Q31a_RS12610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q31a_RS12615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Q31a_RS12645	COG0653	protein targeting
Q31a_RS12670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Q31a_RS12690	COG3273	potassium ion transport
Q31a_RS12690	COG0471	metal ion transport
Q31a_RS12695	COG0579	oxidoreductase
Q31a_RS12700	COG0657	acetylesterase activity
Q31a_RS12705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Q31a_RS12710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Q31a_RS12720	COG3253	May function as heme-dependent peroxidase
Q31a_RS12725	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_RS12730	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_RS12750	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_RS12755	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Q31a_RS12760	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_RS12770	COG1252	NADH dehydrogenase
Q31a_RS12775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS12780	COG3104	oligopeptide transport
Q31a_RS12785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q31a_RS12790	COG3938	Belongs to the proline racemase family
Q31a_RS12805	COG2205	protein histidine kinase activity
Q31a_RS12805	COG5002	protein histidine kinase activity
Q31a_RS12805	COG0784	Response regulator, receiver
Q31a_RS12830	COG3494	Protein of unknown function (DUF1009)
Q31a_RS12835	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_RS12845	COG0268	Binds directly to 16S ribosomal RNA
Q31a_RS12855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Q31a_RS12875	COG3258	Cytochrome c
Q31a_RS12885	COG3119	arylsulfatase activity
Q31a_RS12900	COG1595	DNA-templated transcription, initiation
Q31a_RS12915	COG3852	Histidine kinase
Q31a_RS12920	COG3002	Belongs to the UPF0753 family
Q31a_RS12925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q31a_RS12930	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q31a_RS12935	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_RS12950	COG0598	Magnesium transport protein CorA
Q31a_RS13070	COG3321	synthase
Q31a_RS13070	COG0604	alcohol dehydrogenase
Q31a_RS13100	COG3119	arylsulfatase activity
Q31a_RS13105	COG4566	intracellular signal transduction
Q31a_RS13110	COG4566	intracellular signal transduction
Q31a_RS13115	COG4191	Histidine kinase
Q31a_RS13130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Q31a_RS13140	COG3408	Glycogen debranching enzyme
Q31a_RS13140	COG3119	arylsulfatase activity
Q31a_RS13185	COG1054	Belongs to the UPF0176 family
Q31a_RS13190	COG0302	gtp cyclohydrolase
Q31a_RS13200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q31a_RS13215	COG1233	COG1233 Phytoene dehydrogenase and related
Q31a_RS13230	COG2971	BadF BadG BcrA BcrD
Q31a_RS13235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Q31a_RS13245	COG3876	Protein conserved in bacteria
Q31a_RS13250	COG3876	Protein conserved in bacteria
Q31a_RS13255	COG0657	acetylesterase activity
Q31a_RS13260	COG3119	arylsulfatase activity
Q31a_RS13275	COG4974	Belongs to the 'phage' integrase family
Q31a_RS13290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_RS13290	COG3153	acetyltransferase
Q31a_RS13295	COG1166	arginine decarboxylase activity
Q31a_RS13300	COG3119	arylsulfatase activity
Q31a_RS13310	COG1301	dicarboxylic acid transport
Q31a_RS13315	COG0673	inositol 2-dehydrogenase activity
Q31a_RS13360	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q31a_RS13370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Q31a_RS13385	COG0753	catalase activity
Q31a_RS13390	COG3685	Protein conserved in bacteria
Q31a_RS13410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q31a_RS13440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q31a_RS13440	COG1017	nitric oxide dioxygenase activity
Q31a_RS13455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q31a_RS13465	COG2912	Transglutaminase-like superfamily
Q31a_RS13480	COG1104	cysteine desulfurase activity
Q31a_RS13520	COG0419	ATPase involved in DNA repair
Q31a_RS13535	COG1484	DNA-dependent DNA replication
Q31a_RS13565	COG2755	lipolytic protein G-D-S-L family
Q31a_RS13595	COG2205	protein histidine kinase activity
Q31a_RS13635	COG3119	arylsulfatase activity
Q31a_RS13660	COG1595	DNA-templated transcription, initiation
Q31a_RS13725	COG2183	response to ionizing radiation
Q31a_RS13765	COG2815	serine threonine protein kinase
Q31a_RS13765	COG0515	serine threonine protein kinase
Q31a_RS13780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_RS13800	COG0347	Belongs to the P(II) protein family
Q31a_RS13820	COG1242	4 iron, 4 sulfur cluster binding
Q31a_RS13825	COG1716	ATPase activity
Q31a_RS13850	COG0626	cystathionine gamma-synthase activity
Q31a_RS13860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Q31a_RS13875	COG3119	arylsulfatase activity
Q31a_RS13880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS13885	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS13925	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS13945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_RS13975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_RS13990	COG3119	arylsulfatase activity
Q31a_RS13995	COG3119	arylsulfatase activity
Q31a_RS14000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_RS14005	COG1418	mRNA catabolic process
Q31a_RS14010	COG3119	arylsulfatase activity
Q31a_RS14015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q31a_RS14040	COG2151	metal-sulfur cluster biosynthetic enzyme
Q31a_RS14050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q31a_RS14055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q31a_RS14060	COG0667	Aldo Keto reductase
Q31a_RS14065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_RS14070	COG1063	alcohol dehydrogenase
Q31a_RS14080	COG3344	reverse transcriptase
Q31a_RS14085	COG2204	response regulator
Q31a_RS14095	COG0784	Response regulator, receiver
Q31a_RS14100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q31a_RS14105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q31a_RS14110	COG2382	esterase
Q31a_RS14140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_RS14150	COG2234	aminopeptidase activity
Q31a_RS14165	COG0012	GTP binding
Q31a_RS14170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q31a_RS14180	COG0582	viral genome integration into host DNA
Q31a_RS14250	COG0366	Alpha amylase catalytic
Q31a_RS14255	COG1215	transferase activity, transferring glycosyl groups
Q31a_RS14280	COG0842	Transport permease protein
Q31a_RS14285	COG1129	ABC transporter
Q31a_RS14285	COG0842	Transport permease protein
Q31a_RS14290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_RS14295	COG0204	Acyl-transferase
Q31a_RS14295	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_RS14305	COG0657	acetylesterase activity
Q31a_RS14350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Q31a_RS14395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Q31a_RS14400	COG0140	phosphoribosyl-ATP diphosphatase activity
Q31a_RS14405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Q31a_RS14415	COG2088	sporulation resulting in formation of a cellular spore
Q31a_RS14420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Q31a_RS14425	COG0105	UTP biosynthetic process
Q31a_RS14435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_RS14440	COG1136	(ABC) transporter
Q31a_RS14440	COG0577	efflux transmembrane transporter activity
Q31a_RS14445	COG0577	efflux transmembrane transporter activity
Q31a_RS14445	COG1136	(ABC) transporter
Q31a_RS14530	COG3300	MHYT domain
Q31a_RS14530	COG5001	Diguanylate cyclase
Q31a_RS14540	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS14590	COG1115	amino acid carrier protein
Q31a_RS14600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q31a_RS14625	COG3118	belongs to the thioredoxin family
Q31a_RS14640	COG4948	Mandelate Racemase Muconate Lactonizing
Q31a_RS14745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_RS14760	COG0714	Associated with various cellular activities
Q31a_RS14800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS14810	COG0573	inorganic phosphate transmembrane transporter activity
Q31a_RS14825	COG2226	methyltransferase
Q31a_RS14830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Q31a_RS14835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q31a_RS14840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_RS14860	COG0481	GTPase activity
Q31a_RS14865	COG1940	carbohydrate kinase activity
Q31a_RS14930	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Q31a_RS14940	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Q31a_RS14970	COG0644	oxidoreductase
Q31a_RS14980	COG3377	Domain of unknown function (DUF1805)
Q31a_RS15035	COG0606	chelatase, subunit chli
Q31a_RS15045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q31a_RS15050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS15060	COG0509	glycine decarboxylation via glycine cleavage system
Q31a_RS15065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q31a_RS15075	COG1454	alcohol dehydrogenase
Q31a_RS15130	COG1845	cytochrome c oxidase, subunit III
Q31a_RS15140	COG2824	Alkylphosphonate utilization operon protein PhnA
Q31a_RS15170	COG0277	FAD linked oxidase domain protein
Q31a_RS15175	COG1297	OPT oligopeptide transporter protein
Q31a_RS15195	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_RS15205	COG2815	serine threonine protein kinase
Q31a_RS15205	COG0515	serine threonine protein kinase
Q31a_RS15210	COG1858	cytochrome C peroxidase
Q31a_RS15240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Q31a_RS15300	COG1668	transmembrane transport
Q31a_RS15305	COG4555	ABC transporter
Q31a_RS15335	COG3119	arylsulfatase activity
Q31a_RS15345	COG0793	Belongs to the peptidase S41A family
Q31a_RS15355	COG3119	arylsulfatase activity
Q31a_RS15365	COG0187	DNA topoisomerase II activity
Q31a_RS15375	COG3239	Fatty acid desaturase
Q31a_RS15385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Q31a_RS15390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q31a_RS15395	COG3119	arylsulfatase activity
Q31a_RS15405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Q31a_RS15410	COG1480	7TM receptor with intracellular HD hydrolase
Q31a_RS15415	COG1702	phosphate starvation-inducible protein PhoH
Q31a_RS15420	COG0575	Belongs to the CDS family
Q31a_RS15425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Q31a_RS15430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Q31a_RS15435	COG4956	integral membrane protein (PIN domain superfamily)
Q31a_RS15485	COG1706	bacterial-type flagellum-dependent cell motility
Q31a_RS15490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Q31a_RS15500	COG4786	Flagellar basal body rod
Q31a_RS15505	COG4786	Flagellar basal body rod
Q31a_RS15515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Q31a_RS15520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q31a_RS15545	COG0420	3'-5' exonuclease activity
Q31a_RS15575	COG3437	response regulator, receiver
Q31a_RS15575	COG4999	Histidine kinase
Q31a_RS15575	COG3850	Histidine kinase
Q31a_RS15575	COG2205	protein histidine kinase activity
Q31a_RS15585	COG3119	arylsulfatase activity
Q31a_RS15620	COG2255	four-way junction helicase activity
Q31a_RS15630	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS15650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_RS15655	COG2030	dehydratase
Q31a_RS15675	COG2814	Major facilitator Superfamily
Q31a_RS15685	COG4555	ABC transporter
Q31a_RS15715	COG0673	inositol 2-dehydrogenase activity
Q31a_RS15720	COG3189	MarR family transcriptional regulator
Q31a_RS15725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q31a_RS15735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q31a_RS15750	COG3119	arylsulfatase activity
Q31a_RS15755	COG1446	asparaginase
Q31a_RS15800	COG3119	arylsulfatase activity
Q31a_RS15805	COG3119	arylsulfatase activity
Q31a_RS15810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_RS15815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q31a_RS15940	COG0788	formyltetrahydrofolate deformylase activity
Q31a_RS15950	COG0124	histidyl-tRNA synthetase
Q31a_RS15960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q31a_RS16005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Q31a_RS16010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Q31a_RS16070	COG0515	serine threonine protein kinase
Q31a_RS16070	COG2815	serine threonine protein kinase
Q31a_RS16085	COG0076	glutamate decarboxylase activity
Q31a_RS16095	COG0604	alcohol dehydrogenase
Q31a_RS16115	COG3119	arylsulfatase activity
Q31a_RS16120	COG3119	arylsulfatase activity
Q31a_RS16130	COG2197	response regulator
Q31a_RS16170	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_RS16175	COG1129	ABC transporter
Q31a_RS16185	COG1879	ABC-type sugar transport system periplasmic component
Q31a_RS16190	COG1869	D-ribose catabolic process
Q31a_RS16195	COG1063	alcohol dehydrogenase
Q31a_RS16225	COG4977	sequence-specific DNA binding
Q31a_RS16225	COG1917	Cupin 2, conserved barrel domain protein
Q31a_RS16240	COG1053	succinate dehydrogenase
Q31a_RS16325	COG2815	serine threonine protein kinase
Q31a_RS16325	COG0515	serine threonine protein kinase
Q31a_RS16360	COG2996	Protein conserved in bacteria
Q31a_RS16380	COG2815	serine threonine protein kinase
Q31a_RS16380	COG0515	serine threonine protein kinase
Q31a_RS16405	COG2084	Dehydrogenase
Q31a_RS16410	COG3395	kinase activity
Q31a_RS16415	COG0235	Class ii aldolase
Q31a_RS16420	COG3622	Belongs to the hyi family
Q31a_RS16425	COG0515	serine threonine protein kinase
Q31a_RS16425	COG2815	serine threonine protein kinase
Q31a_RS16460	COG0246	Mannitol dehydrogenase
Q31a_RS16565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_RS16585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS16605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS16635	COG1111	helicase
Q31a_RS16635	COG1205	dead DEAH box helicase
Q31a_RS16670	COG3415	Transposase
Q31a_RS16670	COG2801	Transposase and inactivated derivatives
Q31a_RS16685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS16760	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Q31a_RS16770	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Q31a_RS16775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Q31a_RS16790	COG0564	pseudouridine synthase activity
Q31a_RS16800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Q31a_RS16805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q31a_RS16820	COG2204	response regulator
Q31a_RS16835	COG4566	intracellular signal transduction
Q31a_RS16845	COG2855	membrane
Q31a_RS16865	COG1233	COG1233 Phytoene dehydrogenase and related
Q31a_RS16870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS16885	COG3119	arylsulfatase activity
Q31a_RS16890	COG1024	Enoyl-CoA hydratase
Q31a_RS16895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Q31a_RS16895	COG2755	lipolytic protein G-D-S-L family
Q31a_RS16945	COG0166	Belongs to the GPI family
Q31a_RS16970	COG1566	PFAM secretion protein HlyD family protein
Q31a_RS16980	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_RS17015	COG3119	arylsulfatase activity
Q31a_RS17020	COG2205	protein histidine kinase activity
Q31a_RS17025	COG0745	RESPONSE REGULATOR receiver
Q31a_RS17035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Q31a_RS17045	COG1116	anion transmembrane transporter activity
Q31a_RS17050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q31a_RS17065	COG2814	Major facilitator Superfamily
Q31a_RS17075	COG0823	Involved in the tonB-independent uptake of proteins
Q31a_RS17095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Q31a_RS17120	COG0515	serine threonine protein kinase
Q31a_RS17120	COG0457	Tetratricopeptide repeat
Q31a_RS17135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Q31a_RS17135	COG0574	Belongs to the PEP-utilizing enzyme family
Q31a_RS17145	COG0793	Belongs to the peptidase S41A family
Q31a_RS17170	COG0525	valine-tRNA ligase activity
Q31a_RS17200	COG0295	cytidine deaminase activity
Q31a_RS17210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q31a_RS17215	COG1053	succinate dehydrogenase
Q31a_RS17220	COG2009	succinate dehydrogenase
Q31a_RS17225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_RS17250	COG1136	(ABC) transporter
Q31a_RS17260	COG4628	conserved protein (DUF2132)
Q31a_RS17265	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Q31a_RS17275	COG3541	Predicted nucleotidyltransferase
Q31a_RS17325	COG1335	isochorismatase
Q31a_RS17340	COG0384	phenazine biosynthesis protein PhzF
Q31a_RS17360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Q31a_RS17375	COG3119	arylsulfatase activity
Q31a_RS17390	COG1321	iron dependent repressor
Q31a_RS17405	COG1131	(ABC) transporter
Q31a_RS17420	COG2258	MOSC domain
Q31a_RS17445	COG3119	arylsulfatase activity
Q31a_RS17460	COG3119	arylsulfatase activity
Q31a_RS17510	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_RS17585	COG4149	molybdate abc transporter
Q31a_RS17590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Q31a_RS17595	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Q31a_RS17605	COG0235	Class ii aldolase
Q31a_RS17610	COG3395	kinase activity
Q31a_RS17625	COG2271	Major facilitator Superfamily
Q31a_RS17635	COG2706	6-phosphogluconolactonase activity
Q31a_RS17660	COG1595	DNA-templated transcription, initiation
Q31a_RS17675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_RS17680	COG1595	DNA-templated transcription, initiation
Q31a_RS17700	COG3119	arylsulfatase activity
Q31a_RS17715	COG3119	arylsulfatase activity
Q31a_RS17735	COG3119	arylsulfatase activity
Q31a_RS17745	COG1595	DNA-templated transcription, initiation
Q31a_RS17750	COG2815	serine threonine protein kinase
Q31a_RS17750	COG0515	serine threonine protein kinase
Q31a_RS17755	COG3119	arylsulfatase activity
Q31a_RS17765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS17805	COG1716	ATPase activity
Q31a_RS17845	COG1191	sigma factor activity
Q31a_RS17935	COG0673	inositol 2-dehydrogenase activity
Q31a_RS18020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS18030	COG0351	phosphomethylpyrimidine kinase
Q31a_RS18040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_RS18045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_RS18085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS18090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS18110	COG0386	Belongs to the glutathione peroxidase family
Q31a_RS18135	COG0072	phenylalanine-tRNA ligase activity
Q31a_RS18140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Q31a_RS18145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Q31a_RS18150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Q31a_RS18185	COG3119	arylsulfatase activity
Q31a_RS18195	COG0800	Aldolase
Q31a_RS18200	COG0673	inositol 2-dehydrogenase activity
Q31a_RS18235	COG1136	(ABC) transporter
Q31a_RS18240	COG4591	ABC-type transport system involved in lipoprotein release permease component
Q31a_RS18260	COG1869	D-ribose catabolic process
Q31a_RS18265	COG0667	Aldo Keto reductase
Q31a_RS18270	COG1640	4-alpha-glucanotransferase
Q31a_RS18275	COG0058	SHG alpha-glucan phosphorylase activity
Q31a_RS18290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Q31a_RS18325	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Q31a_RS18325	COG3266	domain, Protein
Q31a_RS18325	COG4932	domain protein
Q31a_RS18330	COG0354	folic acid binding
Q31a_RS18350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q31a_RS18375	COG1216	Glycosyl transferase, family 2
Q31a_RS18390	COG0698	ribose 5-phosphate isomerase
Q31a_RS18395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q31a_RS18415	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Q31a_RS18420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q31a_RS18435	COG3119	arylsulfatase activity
Q31a_RS18440	COG3119	arylsulfatase activity
Q31a_RS18445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS18455	COG1073	alpha beta
Q31a_RS18495	COG3119	arylsulfatase activity
Q31a_RS18540	COG0515	serine threonine protein kinase
Q31a_RS18540	COG2815	serine threonine protein kinase
Q31a_RS18545	COG1595	DNA-templated transcription, initiation
Q31a_RS18565	COG3795	YCII-related domain
Q31a_RS18570	COG3795	YCII-related domain
Q31a_RS18590	COG4941	Belongs to the sigma-70 factor family
Q31a_RS18600	COG3361	conserved protein (COG2071)
Q31a_RS18605	COG1090	epimerase
Q31a_RS18610	COG1294	oxidase, subunit
Q31a_RS18615	COG1271	oxidase subunit
Q31a_RS18665	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS18670	COG1228	amidohydrolase
Q31a_RS18695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_RS18805	COG2205	protein histidine kinase activity
Q31a_RS18820	COG2815	serine threonine protein kinase
Q31a_RS18820	COG0515	serine threonine protein kinase
Q31a_RS18845	COG2801	Transposase and inactivated derivatives
Q31a_RS18875	COG3119	arylsulfatase activity
Q31a_RS18925	COG0657	acetylesterase activity
Q31a_RS18930	COG3119	arylsulfatase activity
Q31a_RS18935	COG3119	arylsulfatase activity
Q31a_RS18950	COG3119	arylsulfatase activity
Q31a_RS18955	COG3119	arylsulfatase activity
Q31a_RS18965	COG2801	Transposase and inactivated derivatives
Q31a_RS18965	COG3415	Transposase
Q31a_RS19010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q31a_RS19010	COG1648	precorrin-2 dehydrogenase activity
Q31a_RS19020	COG2197	response regulator
Q31a_RS19085	COG0784	Response regulator, receiver
Q31a_RS19085	COG2205	protein histidine kinase activity
Q31a_RS19280	COG0464	growth
Q31a_RS19335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q31a_RS19365	COG0653	protein targeting
Q31a_RS19515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS19525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_RS19530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS19625	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Q31a_RS19700	COG2217	Heavy metal translocating P-type atpase
Q31a_RS19710	COG2132	Multicopper oxidase
Q31a_RS19715	COG1937	Protein conserved in bacteria
Q31a_RS19765	COG1595	DNA-templated transcription, initiation
Q31a_RS19820	COG3118	belongs to the thioredoxin family
Q31a_RS19825	COG2217	Heavy metal translocating P-type atpase
Q31a_RS19900	COG0789	Transcriptional regulator
Q31a_RS19920	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_RS19950	COG2815	serine threonine protein kinase
Q31a_RS19950	COG0515	serine threonine protein kinase
Q31a_RS19980	COG4974	Belongs to the 'phage' integrase family
Q31a_RS20035	COG4804	nuclease activity
Q31a_RS20040	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Q31a_RS20140	COG1475	DNA binding
Q31a_RS20255	COG1164	Oligoendopeptidase f
Q31a_RS20270	COG1073	alpha beta
Q31a_RS20275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q31a_RS20350	COG0440	acetolactate synthase activity
Q31a_RS20355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Q31a_RS20360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q31a_RS20400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Q31a_RS20405	COG0489	protein tyrosine kinase activity
Q31a_RS20410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Q31a_RS20415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_RS20435	COG0110	maltose O-acetyltransferase activity
Q31a_RS20465	COG0297	glycogen (starch) synthase activity
Q31a_RS20465	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS20470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS20495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_RS20505	COG1086	Polysaccharide biosynthesis protein
Q31a_RS20580	COG0714	Associated with various cellular activities
Q31a_RS20600	COG0288	reversible hydration of carbon dioxide
Q31a_RS20610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Q31a_RS20615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q31a_RS20630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q31a_RS20635	COG0187	DNA topoisomerase II activity
Q31a_RS20655	COG0714	Associated with various cellular activities
Q31a_RS20665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q31a_RS20675	COG1272	protein, Hemolysin III
Q31a_RS20685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q31a_RS20700	COG0494	nUDIX hydrolase
Q31a_RS20715	COG0175	sulfate reduction
Q31a_RS20720	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Q31a_RS20725	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_RS20730	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_RS20740	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_RS20745	COG1013	pyruvate-flavodoxin oxidoreductase activity
Q31a_RS20750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Q31a_RS20750	COG0674	pyruvate-flavodoxin oxidoreductase activity
Q31a_RS20755	COG0126	phosphoglycerate kinase activity
Q31a_RS20760	COG1609	Transcriptional regulator
Q31a_RS20770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_RS20775	COG1879	ABC-type sugar transport system periplasmic component
Q31a_RS20780	COG1129	ABC transporter
Q31a_RS20785	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_RS20800	COG0243	molybdopterin cofactor binding
Q31a_RS20815	COG0437	4 iron, 4 sulfur cluster binding
Q31a_RS20840	COG3119	arylsulfatase activity
Q31a_RS20845	COG1129	ABC transporter
Q31a_RS20850	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_RS20865	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Q31a_RS20935	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q31a_RS20955	COG0720	synthase
Q31a_RS20960	COG1694	Mazg nucleotide pyrophosphohydrolase
Q31a_RS20975	COG1090	epimerase
Q31a_RS20980	COG1686	Belongs to the peptidase S11 family
Q31a_RS20990	COG0284	orotidine-5'-phosphate decarboxylase activity
Q31a_RS21010	COG1194	a g-specific adenine glycosylase
Q31a_RS21030	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Q31a_RS21070	COG1228	amidohydrolase
Q31a_RS21090	COG2204	response regulator
Q31a_RS21095	COG2205	protein histidine kinase activity
Q31a_RS21115	COG3118	belongs to the thioredoxin family
Q31a_RS21130	COG0612	Peptidase, M16
Q31a_RS21140	COG0515	serine threonine protein kinase
Q31a_RS21145	COG0673	inositol 2-dehydrogenase activity
Q31a_RS21185	COG0719	Fe-S assembly protein
Q31a_RS21190	COG0719	Fe-S assembly protein
Q31a_RS21195	COG0396	ATPase activity
Q31a_RS21215	COG0686	Belongs to the AlaDH PNT family
Q31a_RS21220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Q31a_RS21225	COG1335	isochorismatase
Q31a_RS21235	COG3119	arylsulfatase activity
Q31a_RS21240	COG2133	pyrroloquinoline quinone binding
Q31a_RS21260	COG0540	Belongs to the ATCase OTCase family
Q31a_RS21265	COG0367	asparagine synthase
Q31a_RS21270	COG3119	arylsulfatase activity
Q31a_RS21275	COG4221	oxidoreductase activity
Q31a_RS21280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q31a_RS21295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Q31a_RS21340	COG0590	tRNA wobble adenosine to inosine editing
Q31a_RS21360	COG1560	Kdo2-lipid A biosynthetic process
Q31a_RS21365	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_RS21385	COG0811	peptide transport
Q31a_RS21415	COG1136	(ABC) transporter
Q31a_RS21420	COG1573	uracil-dna glycosylase
Q31a_RS21425	COG1160	GTP binding
Q31a_RS21430	COG0693	protein deglycase activity
Q31a_RS21590	COG2815	serine threonine protein kinase
Q31a_RS21590	COG0515	serine threonine protein kinase
Q31a_RS21615	COG0640	Transcriptional regulator
Q31a_RS21680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_RS21685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_RS21690	COG0167	dihydroorotate dehydrogenase activity
Q31a_RS21715	COG3209	COG3209 Rhs family protein
Q31a_RS21735	COG4797	methyltransferase
Q31a_RS21735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_RS21790	COG0673	inositol 2-dehydrogenase activity
Q31a_RS21810	COG4191	Histidine kinase
Q31a_RS21810	COG0784	Response regulator, receiver
Q31a_RS21840	COG0702	epimerase
Q31a_RS21860	COG0366	Alpha amylase catalytic
Q31a_RS21865	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS21870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q31a_RS21875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q31a_RS21880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q31a_RS21890	COG0356	it plays a direct role in the translocation of protons across the membrane
Q31a_RS21910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q31a_RS21915	COG0693	protein deglycase activity
Q31a_RS21930	COG2217	Heavy metal translocating P-type atpase
Q31a_RS21945	COG0058	SHG alpha-glucan phosphorylase activity
Q31a_RS21950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Q31a_RS21955	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Q31a_RS21960	COG0406	alpha-ribazole phosphatase activity
Q31a_RS21970	COG0842	Transport permease protein
Q31a_RS21970	COG1129	ABC transporter
Q31a_RS21980	COG2130	NADP-dependent
Q31a_RS21985	COG0167	dihydroorotate dehydrogenase activity
Q31a_RS21990	COG2204	response regulator
Q31a_RS21995	COG4191	Histidine kinase
Q31a_RS22000	COG2204	response regulator
Q31a_RS22005	COG4191	Histidine kinase
Q31a_RS22010	COG3852	Histidine kinase
Q31a_RS22035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_RS22055	COG1858	cytochrome C peroxidase
Q31a_RS22080	COG1136	(ABC) transporter
Q31a_RS22080	COG0577	efflux transmembrane transporter activity
Q31a_RS22105	COG5002	protein histidine kinase activity
Q31a_RS22110	COG0745	RESPONSE REGULATOR receiver
Q31a_RS22125	COG0589	response to stress
Q31a_RS22130	COG1283	sodium-dependent phosphate transmembrane transporter activity
Q31a_RS22140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q31a_RS22155	COG1295	ribonuclease BN
Q31a_RS22160	COG0443	Heat shock 70 kDa protein
Q31a_RS22175	COG0515	serine threonine protein kinase
Q31a_RS22195	COG0563	adenylate kinase activity
Q31a_RS22235	COG2391	methyltransferase activity
Q31a_RS22240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_RS22240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q31a_RS22250	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS22260	COG3685	Protein conserved in bacteria
Q31a_RS22265	COG0288	reversible hydration of carbon dioxide
Q31a_RS22270	COG3781	membrane
Q31a_RS22275	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS22280	COG0300	oxidoreductase activity
Q31a_RS22315	COG3119	arylsulfatase activity
Q31a_RS22360	COG3119	arylsulfatase activity
Q31a_RS22380	COG0456	acetyltransferase
Q31a_RS22385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q31a_RS22400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_RS22405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Q31a_RS22425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q31a_RS22430	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Q31a_RS22435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_RS22450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q31a_RS22460	COG0069	glutamate synthase activity
Q31a_RS22475	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS22490	COG0450	alkyl hydroperoxide reductase
Q31a_RS22505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_RS22525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q31a_RS22535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Q31a_RS22545	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q31a_RS22570	COG0148	phosphopyruvate hydratase activity
Q31a_RS22580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Q31a_RS22585	COG2815	serine threonine protein kinase
Q31a_RS22585	COG0515	serine threonine protein kinase
Q31a_RS22590	COG0077	Prephenate dehydratase
Q31a_RS22590	COG1605	Chorismate mutase
Q31a_RS22595	COG0443	Heat shock 70 kDa protein
Q31a_RS22600	COG0542	response to heat
Q31a_RS22610	COG0275	rRNA processing
Q31a_RS22615	COG2001	Belongs to the MraZ family
Q31a_RS22620	COG1706	bacterial-type flagellum-dependent cell motility
Q31a_RS22625	COG1196	nuclear chromosome segregation
Q31a_RS22635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_RS22640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q31a_RS22645	COG0314	molybdopterin synthase activity
Q31a_RS22655	COG0277	FAD linked oxidase domain protein
Q31a_RS22695	COG0617	tRNA 3'-terminal CCA addition
Q31a_RS22715	COG0142	geranyltranstransferase activity
Q31a_RS22720	COG0315	cyclic pyranopterin monophosphate synthase activity
Q31a_RS22735	COG1132	(ABC) transporter
Q31a_RS22745	COG4106	trans-aconitate 2-methyltransferase activity
Q31a_RS22765	COG4566	intracellular signal transduction
Q31a_RS22775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q31a_RS22780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q31a_RS22830	COG1450	Type ii and iii secretion system protein
Q31a_RS22840	COG3344	reverse transcriptase
Q31a_RS22850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Q31a_RS22915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS22925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS22950	COG2204	response regulator
Q31a_RS22955	COG3852	Histidine kinase
Q31a_RS22960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Q31a_RS22965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_RS22980	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_RS22985	COG4191	Histidine kinase
Q31a_RS22990	COG2204	response regulator
Q31a_RS23000	COG0288	reversible hydration of carbon dioxide
Q31a_RS23020	COG0493	'glutamate synthase
Q31a_RS23020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Q31a_RS23045	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS23050	COG1104	cysteine desulfurase activity
Q31a_RS23055	COG4112	unkown
Q31a_RS23060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Q31a_RS23065	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS23070	COG0740	serine-type endopeptidase activity
Q31a_RS23075	COG0740	serine-type endopeptidase activity
Q31a_RS23080	COG0544	peptidyl-prolyl cis-trans isomerase activity
Q31a_RS23095	COG0305	Participates in initiation and elongation during chromosome replication
Q31a_RS23100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Q31a_RS23105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Q31a_RS23115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Q31a_RS23120	COG0193	aminoacyl-tRNA hydrolase activity
Q31a_RS23125	COG0360	Binds together with S18 to 16S ribosomal RNA
Q31a_RS23130	COG0629	single-stranded DNA binding
Q31a_RS23135	COG0359	binds to the 23S rRNA
Q31a_RS23145	COG1476	TRANSCRIPTIONal
Q31a_RS23160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS23170	COG4974	Belongs to the 'phage' integrase family
Q31a_RS23230	COG1802	Transcriptional regulator
Q31a_RS23230	COG4626	Terminase
Q31a_RS23335	COG4974	Belongs to the 'phage' integrase family
Q31a_RS23405	COG1073	alpha beta
Q31a_RS23465	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS23480	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Q31a_RS23505	COG0481	GTPase activity
Q31a_RS23515	COG2354	Protein conserved in bacteria
Q31a_RS23565	COG0367	asparagine synthase
Q31a_RS23585	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS23590	COG2192	nodulation
Q31a_RS23595	COG1696	Membrane protein involved in D-alanine export
Q31a_RS23605	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS23640	COG1215	transferase activity, transferring glycosyl groups
Q31a_RS23680	COG2197	response regulator
Q31a_RS23690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q31a_RS23710	COG1136	(ABC) transporter
Q31a_RS23710	COG0577	efflux transmembrane transporter activity
Q31a_RS23775	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_RS23785	COG3386	PFAM SMP-30 Gluconolaconase
Q31a_RS23790	COG3119	arylsulfatase activity
Q31a_RS23795	COG0316	Belongs to the HesB IscA family
Q31a_RS23805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q31a_RS23810	COG5002	protein histidine kinase activity
Q31a_RS23815	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Q31a_RS23835	COG1606	tRNA processing
Q31a_RS23855	COG0356	it plays a direct role in the translocation of protons across the membrane
Q31a_RS23860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q31a_RS23865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q31a_RS23870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q31a_RS23875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q31a_RS23880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q31a_RS23885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q31a_RS23890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Q31a_RS23900	COG0673	inositol 2-dehydrogenase activity
Q31a_RS23905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q31a_RS23915	COG1254	Belongs to the acylphosphatase family
Q31a_RS23925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Q31a_RS23935	COG2379	hydroxypyruvate reductase
Q31a_RS23950	COG0515	serine threonine protein kinase
Q31a_RS23975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS23980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS23980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_RS23995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS24340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q31a_RS24340	COG1017	nitric oxide dioxygenase activity
Q31a_RS24345	COG0571	ribonuclease III activity
Q31a_RS24350	COG0673	inositol 2-dehydrogenase activity
Q31a_RS24355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Q31a_RS24360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_RS24380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Q31a_RS24390	COG1570	exodeoxyribonuclease VII activity
Q31a_RS24400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Q31a_RS24405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Q31a_RS24410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Q31a_RS24415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Q31a_RS24420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q31a_RS24440	COG1063	alcohol dehydrogenase
Q31a_RS24445	COG0156	8-amino-7-oxononanoate synthase activity
Q31a_RS24450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q31a_RS24470	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_RS24480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Q31a_RS24485	COG1546	Belongs to the CinA family
Q31a_RS24485	COG1058	Belongs to the CinA family
Q31a_RS24510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Q31a_RS24525	COG4771	TonB-dependent receptor
Q31a_RS24530	COG2239	Acts as a magnesium transporter
Q31a_RS24550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS24555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_RS24595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Q31a_RS24600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q31a_RS24620	COG1214	PFAM Peptidase M22, glycoprotease
Q31a_RS24660	COG2204	response regulator
Q31a_RS24665	COG0045	succinate-CoA ligase (ADP-forming) activity
Q31a_RS24670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Q31a_RS24680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Q31a_RS24700	COG0612	Peptidase, M16
Q31a_RS24705	COG0612	Peptidase, M16
Q31a_RS24715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Q31a_RS24720	COG0484	heat shock protein binding
Q31a_RS24725	COG0459	protein refolding
Q31a_RS24730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q31a_RS24735	COG0459	protein refolding
Q31a_RS24745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS24745	COG0706	membrane insertase activity
Q31a_RS24750	COG1760	l-serine dehydratase
Q31a_RS24785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Q31a_RS24805	COG0500	methyltransferase
Q31a_RS24825	COG0778	Nitroreductase
Q31a_RS24830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Q31a_RS24860	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q31a_RS24870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Q31a_RS24890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Q31a_RS24915	COG0445	tRNA wobble uridine modification
Q31a_RS24920	COG0745	RESPONSE REGULATOR receiver
Q31a_RS24925	COG3852	Histidine kinase
Q31a_RS24930	COG1757	Na H antiporter
Q31a_RS24945	COG1677	Flagellar hook-basal body complex protein FliE
Q31a_RS24960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q31a_RS24965	COG1419	protein localization to endoplasmic reticulum
Q31a_RS24980	COG1191	sigma factor activity
Q31a_RS24995	COG1157	protein secretion by the type III secretion system
Q31a_RS25015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Q31a_RS25035	COG1078	dGTPase activity
Q31a_RS25080	COG1136	(ABC) transporter
Q31a_RS25085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Q31a_RS25090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Q31a_RS25110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Q31a_RS25135	COG0542	response to heat
Q31a_RS25155	COG0805	protein transport
Q31a_RS25160	COG1482	cell wall glycoprotein biosynthetic process
Q31a_RS25175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_RS25175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_RS25180	COG0335	large ribosomal subunit rRNA binding
Q31a_RS25185	COG0792	nuclease activity
Q31a_RS25200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Q31a_RS25220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS25245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q31a_RS25250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q31a_RS25255	COG0509	glycine decarboxylation via glycine cleavage system
Q31a_RS25260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q31a_RS25270	COG0811	peptide transport
Q31a_RS25275	COG0848	biopolymer transport protein
Q31a_RS25285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Q31a_RS25290	COG0628	permease
Q31a_RS25310	COG0515	serine threonine protein kinase
Q31a_RS25310	COG2815	serine threonine protein kinase
Q31a_RS25320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q31a_RS25325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q31a_RS25335	COG1722	exodeoxyribonuclease VII activity
Q31a_RS25350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Q31a_RS25355	COG0563	adenylate kinase activity
Q31a_RS25360	COG1032	radical SAM domain protein
Q31a_RS25365	COG0604	alcohol dehydrogenase
Q31a_RS25425	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q31a_RS25435	COG2226	methyltransferase
Q31a_RS25445	COG2815	serine threonine protein kinase
Q31a_RS25445	COG0515	serine threonine protein kinase
Q31a_RS25450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q31a_RS25465	COG0673	inositol 2-dehydrogenase activity
Q31a_RS25480	COG0583	DNA-binding transcription factor activity
Q31a_RS25485	COG0067	glutamate synthase
Q31a_RS25485	COG0069	glutamate synthase activity
Q31a_RS25485	COG0070	glutamate synthase
Q31a_RS25490	COG0493	'glutamate synthase
Q31a_RS25500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Q31a_RS25505	COG4974	Belongs to the 'phage' integrase family
Q31a_RS25520	COG0811	peptide transport
Q31a_RS25540	COG0515	serine threonine protein kinase
Q31a_RS25540	COG2815	serine threonine protein kinase
Q31a_RS25545	COG0039	L-malate dehydrogenase activity
Q31a_RS25565	COG0215	cysteine-tRNA ligase activity
Q31a_RS25570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Q31a_RS25575	COG0632	four-way junction helicase activity
Q31a_RS25585	COG0596	Alpha beta hydrolase
Q31a_RS25605	COG0594	ribonuclease P activity
Q31a_RS25610	COG1595	DNA-templated transcription, initiation
Q31a_RS25645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS25655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_RS25665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_RS25690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Q31a_RS25710	COG2135	peptidase activity
Q31a_RS25735	COG0564	pseudouridine synthase activity
Q31a_RS25765	COG2239	Acts as a magnesium transporter
Q31a_RS25770	COG1691	(AIR) carboxylase
Q31a_RS25775	COG0137	argininosuccinate synthase activity
Q31a_RS25785	COG1490	D-aminoacyl-tRNA deacylase activity
Q31a_RS25805	COG0825	malonyl-CoA metabolic process
Q31a_RS25810	COG0515	serine threonine protein kinase
Q31a_RS25815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q31a_RS25825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Q31a_RS25890	COG0489	protein tyrosine kinase activity
Q31a_RS25910	COG1216	Glycosyl transferase, family 2
Q31a_RS26010	COG3119	arylsulfatase activity
Q31a_RS26035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Q31a_RS26040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q31a_RS26045	COG2264	protein methyltransferase activity
Q31a_RS26055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_RS26095	COG0848	biopolymer transport protein
Q31a_RS26100	COG0848	biopolymer transport protein
Q31a_RS26135	COG0457	Tetratricopeptide repeat
Q31a_RS26140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Q31a_RS26165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Q31a_RS26200	COG5002	protein histidine kinase activity
Q31a_RS26205	COG0704	Plays a role in the regulation of phosphate uptake
Q31a_RS26210	COG0745	RESPONSE REGULATOR receiver
Q31a_RS26215	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS26230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Q31a_RS26235	COG0724	RNA recognition motif
Q31a_RS26240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Q31a_RS26250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Q31a_RS26255	COG0228	four-way junction DNA binding
Q31a_RS26260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Q31a_RS26275	COG0004	ammonium transporteR
Q31a_RS26285	COG0552	protein localization to endoplasmic reticulum
Q31a_RS26295	COG0235	Class ii aldolase
Q31a_RS26315	COG4946	Tricorn protease homolog
Q31a_RS26315	COG0793	Belongs to the peptidase S41A family
Q31a_RS26320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Q31a_RS26325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Q31a_RS26345	COG0457	Tetratricopeptide repeat
Q31a_RS26345	COG0859	PFAM glycosyl transferase family 9
Q31a_RS26350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_RS26375	COG2176	DNA-directed DNA polymerase activity
Q31a_RS26410	COG1063	alcohol dehydrogenase
Q31a_RS26415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_RS26420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Q31a_RS26425	COG1217	gtp-binding protein TYPA
Q31a_RS26445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q31a_RS26450	COG3706	GGDEF domain
Q31a_RS26460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_RS26480	COG0628	permease
Q31a_RS26500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q31a_RS26500	COG2205	protein histidine kinase activity
Q31a_RS26505	COG5487	UPF0391 membrane protein
Q31a_RS26525	COG3237	CsbD-like
Q31a_RS26550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Q31a_RS26575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_RS26580	COG2304	oxidoreductase activity
Q31a_RS26595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Q31a_RS26600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q31a_RS26615	COG2255	four-way junction helicase activity
Q31a_RS26645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Q31a_RS26650	COG0196	riboflavin kinase activity
Q31a_RS26655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q31a_RS26670	COG1725	Transcriptional regulator
Q31a_RS26675	COG1131	(ABC) transporter
Q31a_RS26700	COG0423	glycine-tRNA ligase activity
Q31a_RS26705	COG2890	protein-(glutamine-N5) methyltransferase activity
Q31a_RS26710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q31a_RS26715	COG0254	rRNA binding
Q31a_RS26720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_RS26730	COG0824	Thioesterase
Q31a_RS26750	COG1131	(ABC) transporter
Q31a_RS26765	COG0424	maF-like protein
Q31a_RS26810	COG0557	exoribonuclease II activity
Q31a_RS26815	COG0745	RESPONSE REGULATOR receiver
Q31a_RS26850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Q31a_RS26855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q31a_RS26860	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_RS26865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_RS26870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_RS26890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_RS26895	COG0676	glucose-6-phosphate 1-epimerase activity
Q31a_RS26915	COG0436	Aminotransferase
Q31a_RS26940	COG2271	Major facilitator Superfamily
Q31a_RS26945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_RS27010	COG4536	flavin adenine dinucleotide binding
Q31a_RS27015	COG4536	flavin adenine dinucleotide binding
Q31a_RS27035	COG0071	Belongs to the small heat shock protein (HSP20) family
Q31a_RS27050	COG0352	thiamine-phosphate diphosphorylase activity
Q31a_RS27080	COG0517	IMP dehydrogenase activity
Q31a_RS27085	COG4974	Belongs to the 'phage' integrase family
Q31a_RS27140	COG1695	Transcriptional regulator
Q31a_RS27150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q31a_RS27160	COG1215	transferase activity, transferring glycosyl groups
Q31a_RS27170	COG1131	(ABC) transporter
Q31a_RS27180	COG1902	pentaerythritol trinitrate reductase activity
Q31a_RS27190	COG0202	RNA polymerase activity
Q31a_RS27195	COG0673	inositol 2-dehydrogenase activity
Q31a_RS27240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_RS27250	COG1446	asparaginase
Q31a_RS27265	COG0746	molybdenum cofactor guanylyltransferase activity
Q31a_RS27275	COG5002	protein histidine kinase activity
Q31a_RS27280	COG0745	RESPONSE REGULATOR receiver
Q31a_RS27300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_RS27345	COG1187	pseudouridine synthase activity
Q31a_RS27360	COG1815	bacterial-type flagellum-dependent cell motility
Q31a_RS27375	COG0336	Belongs to the RNA methyltransferase TrmD family
Q31a_RS27380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Q31a_RS27405	COG0174	glutamine synthetase
Q31a_RS27415	COG1477	protein flavinylation
Q31a_RS27420	COG2871	sodium ion transport
Q31a_RS27425	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_RS27430	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_RS27435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_RS27440	COG1805	sodium ion transport
Q31a_RS27455	COG3119	arylsulfatase activity
Q31a_RS27480	COG1131	(ABC) transporter
Q31a_RS27490	COG0577	efflux transmembrane transporter activity
Q31a_RS27490	COG1136	(ABC) transporter
Q31a_RS27510	COG3263	regulation of cellular component size
Q31a_RS27530	COG1663	tetraacyldisaccharide 4'-kinase activity
Q31a_RS27535	COG2721	sulfolactate sulfo-lyase activity
Q31a_RS27555	COG3842	ATPase activity
Q31a_RS27615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q31a_RS27630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q31a_RS27635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q31a_RS27645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Q31a_RS27680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_RS27725	COG0483	inositol monophosphate 1-phosphatase activity
Q31a_RS27730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Q31a_RS27735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q31a_RS27745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Q31a_RS27755	COG0631	protein serine/threonine phosphatase activity
Q31a_RS27770	COG4191	Histidine kinase
Q31a_RS27775	COG2204	response regulator
Q31a_RS27795	COG0714	Associated with various cellular activities
Q31a_RS27810	COG1132	(ABC) transporter
Q31a_RS27815	COG2003	Belongs to the UPF0758 family
Q31a_RS27820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Q31a_RS27840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Q31a_RS27845	COG1131	(ABC) transporter
Q31a_RS27860	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q31a_RS27865	COG1684	flagellar biosynthetic protein fliR
Q31a_RS27875	COG1338	Plays a role in the flagellum-specific transport system
Q31a_RS27895	COG1360	Flagellar Motor Protein
Q31a_RS27900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q31a_RS27905	COG1582	Flagellar protein (FlbD)
Q31a_RS27910	COG1162	GTPase activity
Q31a_RS27915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_RS27920	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_RS27925	COG2045	Belongs to the ComB family
Q31a_RS27930	COG0159	tryptophan synthase activity
Q31a_RS27935	COG0133	tryptophan synthase activity
Q31a_RS27945	COG2192	nodulation
Q31a_RS27975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_RS28040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_RS28050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Q31a_RS28055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Q31a_RS28065	COG0217	transcriptional regulatory protein
Q31a_RS28080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q31a_RS28095	COG4221	oxidoreductase activity
Q31a_RS28100	COG3119	arylsulfatase activity
Q31a_RS28105	COG2115	Belongs to the xylose isomerase family
Q31a_RS28135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q31a_RS28140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_RS28145	COG0243	molybdopterin cofactor binding
Q31a_RS28150	COG0437	4 iron, 4 sulfur cluster binding
Q31a_RS28150	COG3064	Membrane
Q31a_RS28155	COG1116	anion transmembrane transporter activity
Q31a_RS28160	COG1116	anion transmembrane transporter activity
Q31a_RS28170	COG1116	anion transmembrane transporter activity
Q31a_RS28170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q31a_RS28205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_RS28220	COG1063	alcohol dehydrogenase
Q31a_RS28290	COG3119	arylsulfatase activity
Q31a_RS28300	COG2815	serine threonine protein kinase
Q31a_RS28300	COG0515	serine threonine protein kinase
Q31a_RS28335	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Q31a_RS28340	COG0438	transferase activity, transferring glycosyl groups
Q31a_RS28370	COG2096	Adenosyltransferase
Q31a_RS28375	COG0347	Belongs to the P(II) protein family
Q31a_RS28420	COG1940	carbohydrate kinase activity
Q31a_RS28435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Q31a_RS28455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Q31a_RS28500	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_RS28505	COG0189	ligase activity
Q31a_RS28510	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Q31a_RS28515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q31a_RS28520	COG0540	Belongs to the ATCase OTCase family
Q31a_RS28525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Q31a_RS28540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Q31a_RS28560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q31a_RS28640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_RS28655	COG3119	arylsulfatase activity
Q31a_RS28715	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Q31a_RS28735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Q31a_RS28745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q31a_RS28760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q31a_RS28765	COG0154	amidase activity
Q31a_RS28770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q31a_RS28775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Q31a_RS28805	COG0673	inositol 2-dehydrogenase activity
Q31a_RS28815	COG2322	membrane
Q31a_RS28845	COG0109	protoheme IX farnesyltransferase activity
Q31a_RS28855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q31a_RS28870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS28885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q31a_RS28885	COG1796	DNA polymerase
Q31a_RS28890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q31a_RS28895	COG0515	serine threonine protein kinase
Q31a_RS28895	COG0457	Tetratricopeptide repeat
Q31a_RS28925	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Q31a_RS28950	COG0165	Argininosuccinate lyase
Q31a_RS28960	COG2204	response regulator
Q31a_RS28970	COG3132	Protein of unknown function, DUF480
Q31a_RS29005	COG3264	Mechanosensitive ion channel
Q31a_RS29005	COG1511	domain protein
Q31a_RS29030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Q31a_RS29030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_RS29050	COG1174	glycine betaine transport
Q31a_RS29100	COG0405	Gamma-glutamyltransferase
Q31a_RS29125	COG1129	ABC transporter
Q31a_RS29135	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_RS29150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q31a_RS29165	COG0697	spore germination
Q31a_RS29175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_RS29185	COG3590	peptidase
Q31a_RS29195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Q31a_RS29210	COG0442	prolyl-tRNA aminoacylation
Q31a_RS29215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Q31a_RS29225	COG3481	metal-dependent phosphohydrolase, HD sub domain
Q31a_RS29235	COG1125	glycine betaine transport
Q31a_RS29235	COG0517	IMP dehydrogenase activity
Q31a_RS29240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Q31a_RS29245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q31a_RS29250	COG0131	Imidazoleglycerol-phosphate dehydratase
Q31a_RS29260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q31a_RS29280	COG1216	Glycosyl transferase, family 2
Q31a_RS29285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Q31a_RS29305	COG0151	Belongs to the GarS family
Q31a_RS29310	COG1331	Highly conserved protein containing a thioredoxin domain
Q31a_RS29330	COG1968	undecaprenyl-diphosphatase activity
Q31a_RS29335	COG1355	regulation of microtubule-based process
Q31a_RS29360	COG0482	sulfurtransferase activity
Q31a_RS29365	COG4864	UPF0365 protein
Q31a_RS29375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q31a_RS29375	COG0506	proline dehydrogenase activity
Q31a_RS29375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q31a_RS29380	COG0631	protein serine/threonine phosphatase activity
Q31a_RS29385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Q31a_RS29420	COG0673	inositol 2-dehydrogenase activity
Q31a_RS29430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_RS29435	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_RS29440	COG5285	phytanoyl-CoA dioxygenase
Q31a_RS29455	COG0243	molybdopterin cofactor binding
Q31a_RS29465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Q31a_RS29470	COG5002	protein histidine kinase activity
Q31a_RS29485	COG0504	CTP synthase activity
Q31a_RS29495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS29510	COG2801	Transposase and inactivated derivatives
Q31a_RS29510	COG3415	Transposase
Q31a_RS29530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q31a_RS29535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q31a_RS29555	COG0714	Associated with various cellular activities
Q31a_RS29575	COG1216	Glycosyl transferase, family 2
Q31a_RS29585	COG3724	N-succinylarginine dihydrolase activity
Q31a_RS29640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_RS29645	COG1295	ribonuclease BN
Q31a_RS29660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS29665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q31a_RS29715	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_RS29725	COG0489	protein tyrosine kinase activity
Q31a_RS29740	COG1450	Type ii and iii secretion system protein
Q31a_RS29765	COG1459	type II secretion system
Q31a_RS29770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_RS29780	COG5002	protein histidine kinase activity
Q31a_RS29800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q31a_RS29825	COG1104	cysteine desulfurase activity
Q31a_RS29930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q31a_RS30130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Q31a_RS30145	COG3119	arylsulfatase activity
Q31a_RS30150	COG2815	serine threonine protein kinase
Q31a_RS30150	COG0515	serine threonine protein kinase
Q31a_RS30210	COG3119	arylsulfatase activity
Q31a_RS30220	COG0581	inorganic phosphate transmembrane transporter activity
Q31a_RS30535	COG0095	Lipoate-protein ligase
Q31a_RS30570	COG0631	protein serine/threonine phosphatase activity
Q31a_RS30615	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS30620	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS30625	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_RS30630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves