locus-tag	class	description
HHJ60_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HHJ60_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HHJ60_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HHJ60_RS00020	ENOG4105EX9	Membrane
HHJ60_RS00025	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HHJ60_RS00030	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HHJ60_RS00035	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HHJ60_RS00040	ENOG41080IJ	Diacylglycerol kinase
HHJ60_RS00045	ENOG4107RB3	L-asparaginase
HHJ60_RS00055	ENOG4107ZVW	dihydroneopterin aldolase
HHJ60_RS00060	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HHJ60_RS00070	ENOG41066DY	Membrane
HHJ60_RS00075	ENOG4108ZMA	Outer membrane lipoprotein
HHJ60_RS00080	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HHJ60_RS00085	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HHJ60_RS00090	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHJ60_RS00095	ENOG4105EUB	pirin domain protein
HHJ60_RS00100	ENOG4108YYH	Nadph-dependent fmn reductase
HHJ60_RS00105	ENOG4108ETH	Formylglycinamide ribotide synthetase
HHJ60_RS00110	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HHJ60_RS00120	ENOG41068D6	Glycosyltransferase
HHJ60_RS00135	ENOG4105CI3	gtp-binding protein typa
HHJ60_RS00140	ENOG4105C5F	glutamine synthetase
HHJ60_RS00150	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HHJ60_RS00155	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HHJ60_RS00160	ENOG4108JU5	Magnesium and cobalt efflux protein
HHJ60_RS00165	ENOG4105DMR	ABC, transporter
HHJ60_RS00170	ENOG4105GBT	ABC transporter
HHJ60_RS00175	ENOG4106PMH	Extracellular solute-binding protein family 3
HHJ60_RS00180	ENOG4105E5Z	arginine transporter ATP-binding subunit
HHJ60_RS00190	ENOG4105K89	arsenate reductase
HHJ60_RS00205	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHJ60_RS00210	ENOG4106KVJ	cytochrome C assembly protein
HHJ60_RS00215	ENOG4108JU6	CBS domain protein
HHJ60_RS00220	ENOG4105M8K	biopolymer transport protein
HHJ60_RS00225	ENOG4105M15	transport protein ExbD
HHJ60_RS00230	ENOG41067XB	TonB family
HHJ60_RS00235	ENOG4105CTS	PTS system mannitol-specific
HHJ60_RS00240	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HHJ60_RS00245	ENOG4105E61	Mannitol repressor protein
HHJ60_RS00250	ENOG4108ST3	glycosyltransferase
HHJ60_RS00255	ENOG4105C2M	dna polymerase I
HHJ60_RS00260	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HHJ60_RS00265	ENOG4105C94	Transporter
HHJ60_RS00290	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HHJ60_RS00295	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HHJ60_RS00300	ENOG4108IJ0	Aspartate ammonia-lyase
HHJ60_RS00305	ENOG4108IQE	Amp-dependent synthetase and ligase
HHJ60_RS00310	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HHJ60_RS00315	ENOG4108WPU	DNA polymerase III subunit psi
HHJ60_RS00320	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HHJ60_RS00330	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HHJ60_RS00335	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HHJ60_RS00340	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HHJ60_RS00345	ENOG4105BZM	domain protein
HHJ60_RS00360	ENOG4108RRZ	Transcription elongation factor GreB
HHJ60_RS00370	ENOG410624X	efflux transporter, rnd family, mfp subunit
HHJ60_RS00375	ENOG4105BZS	acriflavin resistance protein
HHJ60_RS00380	ENOG4106N3A	copper homeostasis protein cutc
HHJ60_RS00385	ENOG4105CK1	PTS System
HHJ60_RS00395	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HHJ60_RS00400	ENOG4105VZJ	PTS System
HHJ60_RS00405	ENOG4105VCP	PTS System
HHJ60_RS00415	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HHJ60_RS00425	ENOG4105C4R	Atp-dependent dna helicase
HHJ60_RS00445	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HHJ60_RS00470	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HHJ60_RS00480	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HHJ60_RS00485	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HHJ60_RS00490	ENOG4105D9N	nucleoside
HHJ60_RS00495	ENOG4105GPY	SprT protein
HHJ60_RS00500	ENOG41065S8	Opacity family porin protein
HHJ60_RS00505	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HHJ60_RS00515	ENOG4105W8Z	4'-phosphopantetheinyl transferase
HHJ60_RS00520	ENOG4107QJR	hflk protein
HHJ60_RS00525	ENOG4105EPW	hflc protein
HHJ60_RS00535	ENOG4105E66	phosphoriboisomerase A
HHJ60_RS00540	ENOG4108JQ1	Dehydrogenase
HHJ60_RS00550	ENOG4105HHA	aminodeoxychorismate lyase
HHJ60_RS00555	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HHJ60_RS00560	ENOG4107QRG	dna polymerase iii
HHJ60_RS00565	ENOG4105F8V	Hydrolase, tatD family
HHJ60_RS00570	ENOG4105RX8	Protein of unknown function (DUF1523)
HHJ60_RS00575	ENOG4105C37	(CBS) domain
HHJ60_RS00580	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HHJ60_RS00585	ENOG4105C25	Primosomal protein n'
HHJ60_RS00590	ENOG41063M6	Cell Division Protein
HHJ60_RS00600	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HHJ60_RS00605	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HHJ60_RS00610	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HHJ60_RS00620	ENOG4105K59	histidine triad (HIT) protein
HHJ60_RS00625	ENOG4105TMB	Formate nitrite transporter
HHJ60_RS00630	ENOG4105C6N	Formate acetyltransferase
HHJ60_RS00635	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HHJ60_RS00640	ENOG4105F1A	Pyruvate formate-lyase
HHJ60_RS00650	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HHJ60_RS00655	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HHJ60_RS00660	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HHJ60_RS00665	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
HHJ60_RS00670	ENOG4105C2J	ABC transporter
HHJ60_RS00675	ENOG4108HWV	)-transporter
HHJ60_RS00680	ENOG4108M1T	Cytochrome c-type biogenesis protein
HHJ60_RS00685	ENOG4108M1T	Cytochrome c-type biogenesis protein
HHJ60_RS00690	ENOG4107QX9	Thiol disulfide interChange protein
HHJ60_RS00695	ENOG4105DA4	cytochrome c-type biogenesis protein
HHJ60_RS00700	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HHJ60_RS00705	ENOG4105X3C	heme exporter protein
HHJ60_RS00710	ENOG41060IM	Heme exporter protein
HHJ60_RS00715	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HHJ60_RS00720	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS00725	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HHJ60_RS00730	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HHJ60_RS00735	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HHJ60_RS00740	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HHJ60_RS00745	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HHJ60_RS00750	ENOG4105C2W	permease
HHJ60_RS00755	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HHJ60_RS00760	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HHJ60_RS00765	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HHJ60_RS00775	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HHJ60_RS00780	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HHJ60_RS00785	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHJ60_RS00790	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HHJ60_RS00795	ENOG4105DFS	Conserved Protein
HHJ60_RS00800	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HHJ60_RS00805	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HHJ60_RS00815	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HHJ60_RS00820	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HHJ60_RS00825	ENOG4105DMQ	Methyltransferase
HHJ60_RS00830	ENOG4105CIC	tryptophan-specific transport protein
HHJ60_RS00835	ENOG4105F0N	pyrophosphate phospho-hydrolase
HHJ60_RS00840	ENOG4105ERG	peptidase m48, ste24p
HHJ60_RS00850	ENOG4108K5P	(LipO)protein
HHJ60_RS00860	ENOG4108UM1	dedA family
HHJ60_RS00865	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HHJ60_RS00870	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HHJ60_RS00875	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HHJ60_RS00885	ENOG4107VXZ	Hydrolase
HHJ60_RS00890	ENOG4108UW5	maltose o-acetyltransferase
HHJ60_RS00895	ENOG4105W39	Membrane
HHJ60_RS00905	ENOG4105CSA	Coproporphyrinogen iii oxidase
HHJ60_RS00910	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HHJ60_RS00915	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HHJ60_RS00920	ENOG4105C7N	Xanthine uracil vitamin C permease
HHJ60_RS00930	ENOG4105CMR	udp-glucose 4-epimerase
HHJ60_RS00935	ENOG4105EYM	Major Facilitator superfamily
HHJ60_RS00940	ENOG4105C09	Bile acid
HHJ60_RS00945	ENOG4105BZU	Histidine kinase
HHJ60_RS00960	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HHJ60_RS00965	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HHJ60_RS00970	ENOG4105CTQ	phosphohexokinase
HHJ60_RS00995	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HHJ60_RS01000	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HHJ60_RS01005	ENOG4105C3F	Signal peptidase i
HHJ60_RS01020	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HHJ60_RS01025	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HHJ60_RS01030	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HHJ60_RS01035	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HHJ60_RS01040	ENOG4105CW7	secretion protein, HlyD family
HHJ60_RS01045	ENOG4105NTK	Transcriptional repressor Mpra
HHJ60_RS01060	ENOG4105NTK	Transcriptional repressor Mpra
HHJ60_RS01065	ENOG4105HMI	Membrane
HHJ60_RS01070	ENOG4105D5K	Hemolysin activator protein
HHJ60_RS01075	ENOG4105CKT	filamentous hemagglutinin
HHJ60_RS01075	ENOG4105CKT	filamentous hemagglutinin
HHJ60_RS01175	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHJ60_RS01180	ENOG4105QYV	Membrane
HHJ60_RS01185	ENOG4105K46	50S ribosomal protein l27
HHJ60_RS01190	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HHJ60_RS01195	ENOG4105EAH	synthase
HHJ60_RS01200	ENOG4105WPN	DNA integration recombination invertion protein
HHJ60_RS01205	ENOG4105K63	Thioredoxin
HHJ60_RS01210	ENOG4105C5I	Dehydrogenase
HHJ60_RS01215	ENOG4105C28	cystathionine
HHJ60_RS01235	ENOG4108KU3	Integrase
HHJ60_RS01295	ENOG4108UUM	single-stranded DNA-binding protein
HHJ60_RS01345	ENOG4107EPN	Domain of unknown function (DUF1508)
HHJ60_RS01350	ENOG4105VUH	addiction module killer protein
HHJ60_RS01355	ENOG4105YES	addiction module antidote protein
HHJ60_RS01370	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HHJ60_RS01410	ENOG4105RWQ	Protein of unknown function (DUF1364)
HHJ60_RS01435	ENOG4107EPN	Domain of unknown function (DUF1508)
HHJ60_RS01540	ENOG4108UUM	single-stranded DNA-binding protein
HHJ60_RS01565	ENOG4105WXW	Antirepressor
HHJ60_RS01575	ENOG4108KU3	Integrase
HHJ60_RS01585	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HHJ60_RS01595	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HHJ60_RS01600	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
HHJ60_RS01610	ENOG4105DFS	Conserved Protein
HHJ60_RS01615	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HHJ60_RS01645	ENOG4108JQC	penicillin-binding protein 1A
HHJ60_RS01670	ENOG4105E4G	Type IV pilus
HHJ60_RS01675	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HHJ60_RS01680	ENOG4105D49	3-dehydroquinate synthase
HHJ60_RS01685	ENOG4105DFE	Dna adenine methylase
HHJ60_RS01700	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HHJ60_RS01705	ENOG4105M6F	mutator MutT protein
HHJ60_RS01710	ENOG4108JA2	transcriptioN-repair coupling factor
HHJ60_RS01725	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HHJ60_RS01770	ENOG4105K4U	addiction module toxin, RelE StbE family
HHJ60_RS01830	ENOG4105C6T	cysteine synthase
HHJ60_RS01840	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HHJ60_RS01845	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HHJ60_RS01850	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HHJ60_RS01855	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HHJ60_RS01860	ENOG4105EYA	deoxyribonuclease
HHJ60_RS01865	ENOG4105D52	delta-aminolevulinic acid dehydratase
HHJ60_RS01870	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HHJ60_RS01875	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HHJ60_RS01880	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HHJ60_RS01885	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HHJ60_RS01890	ENOG4105JC1	sterol-binding domain protein
HHJ60_RS01895	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HHJ60_RS01900	ENOG4105C8P	)-transporter
HHJ60_RS01905	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HHJ60_RS01910	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HHJ60_RS01915	ENOG4108R96	Methyltransferase, YaeB family
HHJ60_RS01920	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HHJ60_RS01925	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HHJ60_RS01930	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHJ60_RS01935	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HHJ60_RS01945	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HHJ60_RS01950	ENOG4105E07	UPF0149 protein
HHJ60_RS01955	ENOG4107RAQ	aminopeptidase
HHJ60_RS01960	ENOG4105D0A	hydroxylase
HHJ60_RS01965	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HHJ60_RS01970	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HHJ60_RS01975	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HHJ60_RS01980	ENOG4105C2J	ABC transporter
HHJ60_RS01985	ENOG4105CNN	ABC, transporter
HHJ60_RS01990	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HHJ60_RS01995	ENOG4105YP7	UPF0270 protein
HHJ60_RS02000	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HHJ60_RS02010	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HHJ60_RS02030	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HHJ60_RS02040	ENOG4105QEK	Transcriptional regulator
HHJ60_RS02045	ENOG4108R66	Conserved Protein
HHJ60_RS02050	ENOG4105EVU	fructokinase
HHJ60_RS02055	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HHJ60_RS02065	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HHJ60_RS02085	ENOG4107ENK	receptor
HHJ60_RS02090	ENOG41090JE	Utilization Protein
HHJ60_RS02095	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HHJ60_RS02105	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HHJ60_RS02110	ENOG4105DFF	Rod shape-determining protein mreb
HHJ60_RS02115	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HHJ60_RS02120	ENOG4108UUM	single-stranded DNA-binding protein
HHJ60_RS02145	ENOG4105ENX	hydrolase
HHJ60_RS02185	ENOG4105EQ2	LysR family Transcriptional regulator
HHJ60_RS02190	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HHJ60_RS02205	ENOG4105CHR	reductase
HHJ60_RS02210	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HHJ60_RS02215	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HHJ60_RS02220	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HHJ60_RS02230	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HHJ60_RS02235	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HHJ60_RS02240	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HHJ60_RS02245	ENOG4105HSA	Protein of unknown function (DUF452)
HHJ60_RS02250	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HHJ60_RS02255	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HHJ60_RS02270	ENOG4105DJ4	phosphatidylserine decarboxylase
HHJ60_RS02275	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HHJ60_RS02285	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HHJ60_RS02290	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HHJ60_RS02295	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HHJ60_RS02300	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HHJ60_RS02305	ENOG4105CB5	ATP-dependent DNA helicase recG
HHJ60_RS02310	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HHJ60_RS02345	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHJ60_RS02350	ENOG4105TWJ	Domain of unknown function (DUF1919)
HHJ60_RS02355	ENOG4105P4J	Allophanate hydrolase, subunit 1
HHJ60_RS02360	ENOG4107R7A	Allophanate hydrolase subunit 2
HHJ60_RS02365	ENOG4105E7W	lamb ycsf family protein
HHJ60_RS02370	ENOG4105C5A	transporter
HHJ60_RS02375	ENOG4105CFP	Peptidase U32
HHJ60_RS02385	ENOG4105SYT	Methylenetetrahydrofolate reductase
HHJ60_RS02395	ENOG4105CGK	Exodeoxyribonuclease III
HHJ60_RS02410	ENOG4105ERU	peptidase
HHJ60_RS02415	ENOG4105C4Y	ABC transporter
HHJ60_RS02420	ENOG4107RN3	metallophosphoesterase
HHJ60_RS02425	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HHJ60_RS02430	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HHJ60_RS02445	ENOG4105DVT	helicase
HHJ60_RS02450	ENOG41072GX	Peptidase M22 Glycoprotease
HHJ60_RS02455	ENOG4105CEY	Amp-dependent synthetase and ligase
HHJ60_RS02460	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HHJ60_RS02475	ENOG4108JJ8	(ABC) transporter
HHJ60_RS02480	ENOG4108JJ9	ABC, transporter
HHJ60_RS02485	ENOG4105C3M	thioredoxin reductase
HHJ60_RS02490	ENOG4107QR8	Thioredoxin
HHJ60_RS02495	ENOG4105C6Z	Gluconate
HHJ60_RS02500	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HHJ60_RS02505	ENOG4105C5H	ABC transporter
HHJ60_RS02510	ENOG4105C8J	)-transporter
HHJ60_RS02515	ENOG4105CSM	endonuclease III
HHJ60_RS02520	ENOG4105DZB	Electron transport complex
HHJ60_RS02525	ENOG4108UQQ	Electron transport complex
HHJ60_RS02530	ENOG4105D6A	Electron transport complex
HHJ60_RS02535	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HHJ60_RS02540	ENOG4108R3D	Electron transport complex
HHJ60_RS02545	ENOG4105DGN	Electron transport complex
HHJ60_RS02550	ENOG4105ECP	epimerase
HHJ60_RS02555	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HHJ60_RS02560	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HHJ60_RS02570	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HHJ60_RS02575	ENOG4105C2X	Arabinose 5-phosphate isomerase
HHJ60_RS02585	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HHJ60_RS02590	ENOG4108DG9	Smr protein MutS2
HHJ60_RS02595	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HHJ60_RS02600	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HHJ60_RS02605	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HHJ60_RS02620	ENOG4105VEQ	Cold shock protein
HHJ60_RS02635	ENOG4105DIQ	Transcriptional regulator
HHJ60_RS02640	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HHJ60_RS02645	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HHJ60_RS02650	ENOG4105DAN	ATP-dependent protease
HHJ60_RS02655	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HHJ60_RS02660	ENOG4108Z66	YbaK ebsC protein
HHJ60_RS02665	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HHJ60_RS02670	ENOG4105C7N	Xanthine uracil vitamin C permease
HHJ60_RS02675	ENOG41090EX	DsrE family
HHJ60_RS02680	ENOG4107QKA	exodeoxyribonuclease V beta
HHJ60_RS02685	ENOG4107QYX	exodeoxyribonuclease v alpha
HHJ60_RS02695	ENOG4105C5S	asparaginyl-tRNA synthetase
HHJ60_RS02700	ENOG4105E2R	ROK family
HHJ60_RS02710	ENOG4105CIY	formyltetrahydrofolate deformylase
HHJ60_RS02715	ENOG4105CVJ	phosphoglycerate mutase
HHJ60_RS02720	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HHJ60_RS02725	ENOG4108W1A	pseudouridine synthase
HHJ60_RS02740	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HHJ60_RS02745	ENOG4108QBX	(LipO)protein
HHJ60_RS02750	ENOG4108NSE	outer membrane autotransporter barrel
HHJ60_RS02760	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HHJ60_RS02765	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HHJ60_RS02775	ENOG4108TZV	Membrane
HHJ60_RS02780	ENOG4105CJB	Exodeoxyribonuclease I
HHJ60_RS02800	ENOG4105KB2	stringent starvation protein b
HHJ60_RS02805	ENOG4107MKT	Stringent starvation protein a
HHJ60_RS02820	ENOG4105DR9	pseudouridine synthase
HHJ60_RS02825	ENOG4105WP7	tRNA pseudouridine synthase C
HHJ60_RS02830	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
HHJ60_RS02845	ENOG4105EWT	decarboxylase family
HHJ60_RS02850	ENOG4105UKP	Protein of unknown function (DUF1778)
HHJ60_RS02860	ENOG4105K64	Glycosyl transferase, family 2
HHJ60_RS02865	ENOG4105E3A	(ABC) transporter
HHJ60_RS02870	ENOG4105DA5	(ABC) transporter
HHJ60_RS02875	ENOG4108BPE	-transporting atpase
HHJ60_RS02880	ENOG4105D0M	Protease HtpX homolog
HHJ60_RS02885	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HHJ60_RS02890	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HHJ60_RS02895	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HHJ60_RS02900	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HHJ60_RS02905	ENOG4108ESZ	Glycogen debranching enzyme
HHJ60_RS02910	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HHJ60_RS02915	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HHJ60_RS02920	ENOG4105KAF	membrAne
HHJ60_RS02925	ENOG4108ZZ3	UPF0260 protein
HHJ60_RS02930	ENOG4105CX6	glutaminyL-tRNA synthetase
HHJ60_RS02935	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HHJ60_RS02940	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHJ60_RS02945	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HHJ60_RS02955	ENOG4107QN2	dihydrolipoyl dehydrogenase
HHJ60_RS02960	ENOG4107QSN	dihydrolipoamide acetyltransferase
HHJ60_RS02965	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HHJ60_RS02970	ENOG4105C5Y	PTS System
HHJ60_RS02975	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HHJ60_RS02980	ENOG4105KZ7	phosphocarrier protein hpr
HHJ60_RS02985	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HHJ60_RS02990	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HHJ60_RS03005	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HHJ60_RS03010	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HHJ60_RS03015	ENOG4105D1H	recombination factor protein RarA
HHJ60_RS03030	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HHJ60_RS03035	ENOG4105CNU	cell division protein FtsK
HHJ60_RS03040	ENOG4105EW9	transcriptional regulator AsnC family
HHJ60_RS03045	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HHJ60_RS03050	ENOG41067MG	lrgb family
HHJ60_RS03055	ENOG4105VAW	lrga family
HHJ60_RS03060	ENOG4105KK6	nuclease
HHJ60_RS03065	ENOG4105C9B	Cysteine desulfurase
HHJ60_RS03070	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HHJ60_RS03075	ENOG4105RHG	
HHJ60_RS03080	ENOG4105D0Y	UPF0227 protein
HHJ60_RS03085	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HHJ60_RS03090	ENOG41090BQ	Glutaredoxin
HHJ60_RS03095	ENOG4107QZM	n-acetylglutamate synthase
HHJ60_RS03110	ENOG4105DJ0	Poly(A) Polymerase
HHJ60_RS03115	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHJ60_RS03120	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HHJ60_RS03130	ENOG4105CTB	Polyprenyl synthetase
HHJ60_RS03135	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HHJ60_RS03140	ENOG4105HBR	Rna-binding protein
HHJ60_RS03145	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HHJ60_RS03150	ENOG4105QVC	MOSC domain-containing protein
HHJ60_RS03160	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HHJ60_RS03165	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HHJ60_RS03170	ENOG4105DB7	PHP domain protein
HHJ60_RS03175	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HHJ60_RS03180	ENOG4105CD8	aminopeptidase N
HHJ60_RS03185	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HHJ60_RS03230	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HHJ60_RS03235	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HHJ60_RS03240	ENOG4105E96	Colicin v production protein
HHJ60_RS03245	ENOG4105PQ6	UPF0208 membrane protein
HHJ60_RS03250	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HHJ60_RS03255	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HHJ60_RS03280	ENOG4105D64	Mechanosensitive ion channel
HHJ60_RS03285	ENOG4108K5H	permease YjgP YjgQ family protein
HHJ60_RS03290	ENOG4108M8S	permease YjgP YjgQ family protein
HHJ60_RS03295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HHJ60_RS03315	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HHJ60_RS03320	ENOG4105D1A	Methyltransferase
HHJ60_RS03325	ENOG4105DDY	UPF0142 protein ycaO
HHJ60_RS03330	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HHJ60_RS03335	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HHJ60_RS03350	ENOG4105XPH	Ferredoxin
HHJ60_RS03360	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HHJ60_RS03365	ENOG4108ZAI	phosphatidylglycerophosphatase a
HHJ60_RS03370	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HHJ60_RS03375	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HHJ60_RS03385	ENOG4105E0U	tyrosine-specific transport protein
HHJ60_RS03395	ENOG4108BY2	phosphohistidine phosphatase
HHJ60_RS03400	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HHJ60_RS03405	ENOG4105EEI	dihydropteroate synthase
HHJ60_RS03415	ENOG4105C0H	protease
HHJ60_RS03420	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HHJ60_RS03425	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HHJ60_RS03465	ENOG4105E9S	glutaredoxin 2
HHJ60_RS03505	ENOG4105DFP	Integrase
HHJ60_RS03525	ENOG4105W1T	Glycosyl Transferase
HHJ60_RS03530	ENOG4105W1T	Glycosyl Transferase
HHJ60_RS03550	ENOG4105D7X	high-affinity nickel-transporter
HHJ60_RS03555	ENOG41065CD	Exported protein
HHJ60_RS03560	ENOG4105C5H	ABC transporter
HHJ60_RS03565	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HHJ60_RS03575	ENOG4105ETE	Transcriptional regulator (LacI family
HHJ60_RS03580	ENOG4108RVA	ribokinase
HHJ60_RS03585	ENOG4105D9N	nucleoside
HHJ60_RS03590	ENOG4105DU0	nucleoside hydrolase
HHJ60_RS03595	ENOG4105C0H	protease
HHJ60_RS03600	ENOG4108MN8	Membrane
HHJ60_RS03605	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HHJ60_RS03615	ENOG4105DIK	(ABC) transporter
HHJ60_RS03620	ENOG4105CC5	ABC transporter
HHJ60_RS03625	ENOG4105CC5	ABC transporter
HHJ60_RS03630	ENOG4105DWV	Homoserine O-trans-acetylase
HHJ60_RS03635	ENOG4107GZ4	SanA protein
HHJ60_RS03640	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HHJ60_RS03645	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HHJ60_RS03650	ENOG4105D60	lipoprotein releasing system transmembrane protein
HHJ60_RS03655	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HHJ60_RS03660	ENOG4105D60	lipoprotein releasing system transmembrane protein
HHJ60_RS03665	ENOG4105C5I	Dehydrogenase
HHJ60_RS03670	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HHJ60_RS03675	ENOG41063JG	Transcriptional regulator
HHJ60_RS03680	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HHJ60_RS03685	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HHJ60_RS03695	ENOG4105EM2	membrane
HHJ60_RS03700	ENOG4108Z5K	methylglyoxal synthase
HHJ60_RS03710	ENOG4108ZAF	Molybdopterin
HHJ60_RS03715	ENOG4105M00	molybdopterin converting factor, subunit 1
HHJ60_RS03720	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HHJ60_RS03725	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HHJ60_RS03765	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HHJ60_RS03770	ENOG4105EUJ	GTP cyclohydrolase i
HHJ60_RS03775	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HHJ60_RS03780	ENOG4105D06	uba thif-type nad fad binding protein
HHJ60_RS03785	ENOG4105DWU	Membrane
HHJ60_RS03790	ENOG41090A1	ferritin
HHJ60_RS03795	ENOG41090A1	ferritin
HHJ60_RS03805	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HHJ60_RS03810	ENOG4105Q9Y	Universal stress protein
HHJ60_RS03820	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HHJ60_RS03825	ENOG4107R11	Transcriptional regulator
HHJ60_RS03830	ENOG4105FE9	pseudouridine synthase
HHJ60_RS03835	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HHJ60_RS03840	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HHJ60_RS03845	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HHJ60_RS03850	ENOG41082RQ	UPF0102 protein
HHJ60_RS03855	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HHJ60_RS03860	ENOG4105W4M	Transport-associated protein
HHJ60_RS03865	ENOG4105C4R	Atp-dependent dna helicase
HHJ60_RS03880	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HHJ60_RS03885	ENOG4105ETT	transcriptional Regulator, LysR family
HHJ60_RS03890	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HHJ60_RS03910	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HHJ60_RS03915	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HHJ60_RS03920	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HHJ60_RS03925	ENOG4105C28	cystathionine
HHJ60_RS03930	ENOG4105D3R	alkyl hydroperoxide reductase
HHJ60_RS03940	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HHJ60_RS03945	ENOG4105D1S	lipid A biosynthesis
HHJ60_RS03950	ENOG4105C5X	domain protein
HHJ60_RS03960	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HHJ60_RS03965	ENOG4105CN1	protease
HHJ60_RS03970	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HHJ60_RS03975	ENOG4105H2K	paraquat-inducible protein a
HHJ60_RS03980	ENOG4105DY2	Paraquat-inducible protein b
HHJ60_RS03985	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHJ60_RS03990	ENOG4105CEI	nitrite reductase
HHJ60_RS03995	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHJ60_RS04000	ENOG4105G0K	glycine radical enzyme YjjI family
HHJ60_RS04005	ENOG41076CZ	activating enzyme
HHJ60_RS04010	ENOG4106B0W	Curli production assembly transport component CsgG
HHJ60_RS04020	ENOG4107Y60	(LipO)protein
HHJ60_RS04025	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HHJ60_RS04030	ENOG4105CC0	LysR family Transcriptional regulator
HHJ60_RS04035	ENOG4105D07	Signal peptide peptidase, SppA
HHJ60_RS04040	ENOG41069NU	Nitroreductase
HHJ60_RS04045	ENOG4105EUB	pirin domain protein
HHJ60_RS04060	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HHJ60_RS04065	ENOG4108ZP8	Acetolactate synthase small subunit
HHJ60_RS04070	ENOG4105C7K	acetolactate synthase
HHJ60_RS04075	ENOG4107S6Z	Na H antiporter
HHJ60_RS04080	ENOG4108YX2	DNA-binding protein
HHJ60_RS04090	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HHJ60_RS04095	ENOG4107QNR	UPF0135 protein
HHJ60_RS04100	ENOG4105ETE	Transcriptional regulator (LacI family
HHJ60_RS04115	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HHJ60_RS04140	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HHJ60_RS04145	ENOG41087AY	ADP-Ribose pyrophosphatase
HHJ60_RS04150	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HHJ60_RS04160	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HHJ60_RS04165	ENOG4105KUZ	arsenate reductase
HHJ60_RS04170	ENOG4105DVP	Adenine-specific
HHJ60_RS04175	ENOG4106NNP	ICEA Protein
HHJ60_RS04185	ENOG4105D98	threonine synthase
HHJ60_RS04190	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HHJ60_RS04195	ENOG4105CFH	Aspartokinase
HHJ60_RS04205	ENOG4105DFA	alanine racemase domain protein
HHJ60_RS04210	ENOG4108UYE	Lactoylglutathione lyase
HHJ60_RS04215	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HHJ60_RS04220	ENOG4105D3Y	Na H antiporter
HHJ60_RS04225	ENOG4105C26	Dehydrogenase
HHJ60_RS04230	ENOG4105CK7	Sodium proline symporter
HHJ60_RS04235	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HHJ60_RS04240	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HHJ60_RS04245	ENOG4105NSG	hemerythrin hhe cation binding domain protein
HHJ60_RS04250	ENOG4105VIE	preprotein translocase, subunit YajC
HHJ60_RS04255	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HHJ60_RS04260	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HHJ60_RS04265	ENOG4107SC1	transglycosylase
HHJ60_RS04270	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HHJ60_RS04275	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HHJ60_RS04280	ENOG4105EMU	Dehydrogenase
HHJ60_RS04285	ENOG4105D8G	Major Facilitator superfamily
HHJ60_RS04310	ENOG4105CKT	filamentous hemagglutinin
HHJ60_RS04335	ENOG4107QMH	DNA methylase
HHJ60_RS04345	ENOG4105EJC	lysr family transcriptional regulator
HHJ60_RS04350	ENOG4105DHQ	Histidine kinase
HHJ60_RS04355	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HHJ60_RS04360	ENOG4105ETU	transcriptional activator (TenA
HHJ60_RS04370	ENOG4105EXC	Acyl-transferase
HHJ60_RS04380	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HHJ60_RS04385	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HHJ60_RS04390	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HHJ60_RS04400	ENOG4106KS4	Sulfatase
HHJ60_RS04410	ENOG4105D2T	synthase
HHJ60_RS04425	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HHJ60_RS04430	ENOG4105D7K	pfkb domain protein
HHJ60_RS04450	ENOG4105K8N	protein family UPF0079, ATPase
HHJ60_RS04455	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HHJ60_RS04460	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HHJ60_RS04470	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HHJ60_RS04475	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HHJ60_RS04485	ENOG4105XW2	UPF0263 protein
HHJ60_RS04500	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HHJ60_RS04510	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
HHJ60_RS04545	ENOG4105D29	Helix-turn-helix type 11 domain protein
HHJ60_RS04560	ENOG4105C2I	pirin domain protein
HHJ60_RS04565	ENOG4105CVE	Lytic murein transglycosylase
HHJ60_RS04570	ENOG4108RYC	glycosyltransferase
HHJ60_RS04575	ENOG4108RJ9	Glycosyl transferase, family 2
HHJ60_RS04585	ENOG41068D6	Glycosyltransferase
HHJ60_RS04595	ENOG4108ZPC	Polysaccharide pyruvyl transferase
HHJ60_RS04600	ENOG41080C8	DUF218 domain
HHJ60_RS04605	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HHJ60_RS04610	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HHJ60_RS04615	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HHJ60_RS04620	ENOG4105D1F	ATP-binding protein
HHJ60_RS04625	ENOG4107SJW	iron permease, FTR1
HHJ60_RS04640	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HHJ60_RS04650	ENOG4105C19	ABC transporter
HHJ60_RS04655	ENOG4105DSB	aldose 1-epimerase
HHJ60_RS04665	ENOG4105CRK	lysyL-tRNA synthetase
HHJ60_RS04680	ENOG4105T95	Thiol disulfide interChange protein
HHJ60_RS04685	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HHJ60_RS04690	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HHJ60_RS04695	ENOG4105UYK	outer membrane protein a
HHJ60_RS04700	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HHJ60_RS04705	ENOG4108UUE	Transcriptional regulator
HHJ60_RS04710	ENOG4105E0A	ABC, transporter
HHJ60_RS04720	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HHJ60_RS04735	ENOG4105E0K	tonB-dependent siderophore receptor
HHJ60_RS04740	ENOG4105E0K	tonB-dependent siderophore receptor
HHJ60_RS04750	ENOG4105C44	Serine transporter
HHJ60_RS04755	ENOG4105WWK	YheO domain protein
HHJ60_RS04765	ENOG4105CA9	Pyruvate kinase
HHJ60_RS04770	ENOG4108RCM	Nitroreductase
HHJ60_RS04775	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HHJ60_RS04780	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HHJ60_RS04785	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HHJ60_RS04795	ENOG4105C7S	Dehydrogenase
HHJ60_RS04800	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HHJ60_RS04805	ENOG4105BZN	citrate synthase
HHJ60_RS04810	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HHJ60_RS04815	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
HHJ60_RS04825	ENOG4107QX8	SPFH domain, Band 7 family protein
HHJ60_RS04830	ENOG4105K3M	)-transporter
HHJ60_RS04850	ENOG4105E2R	ROK family
HHJ60_RS04860	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HHJ60_RS04865	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HHJ60_RS04870	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HHJ60_RS04875	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HHJ60_RS04885	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HHJ60_RS04890	ENOG4105C8Y	Acetylornithine aminotransferase
HHJ60_RS04895	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HHJ60_RS04900	ENOG4105C03	ribonuclease
HHJ60_RS04955	ENOG4105ESV	Glycosyl transferase, family 4
HHJ60_RS04960	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HHJ60_RS04965	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HHJ60_RS04970	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HHJ60_RS04975	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HHJ60_RS04980	ENOG4108ZIG	UPF0231 protein
HHJ60_RS04985	ENOG4105BZ4	penicillin-binding protein
HHJ60_RS04995	ENOG4107TSG	Extracellular solute-binding protein, family 5
HHJ60_RS05000	ENOG4105WD1	Membrane
HHJ60_RS05005	ENOG4105DGW	oligopeptidase A
HHJ60_RS05015	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HHJ60_RS05020	ENOG4105E33	succinate dehydrogenase
HHJ60_RS05025	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HHJ60_RS05030	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HHJ60_RS05035	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HHJ60_RS05040	ENOG4105NXV	High-affinity zinc uptake system protein
HHJ60_RS05045	ENOG4105CUZ	uba thif-type nad fad binding protein
HHJ60_RS05050	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HHJ60_RS05065	ENOG4105VEQ	Cold shock protein
HHJ60_RS05070	ENOG4105DFU	Cell wall formation (By similarity)
HHJ60_RS05080	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HHJ60_RS05085	ENOG4105VFK	BolA family
HHJ60_RS05095	ENOG4105E3I	toluene tolerance
HHJ60_RS05100	ENOG4107PE3	Mammalian cell entry related domain protein
HHJ60_RS05105	ENOG4105CY3	ABC transporter, permease
HHJ60_RS05110	ENOG4105DHJ	ABC, transporter
HHJ60_RS05120	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HHJ60_RS05125	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HHJ60_RS05130	ENOG4108IUZ	ABC transporter
HHJ60_RS05135	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HHJ60_RS05150	ENOG4107YCY	Transcriptional regulator
HHJ60_RS05160	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HHJ60_RS05165	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HHJ60_RS05175	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HHJ60_RS05180	ENOG4105DMW	Dehydrogenase reductase
HHJ60_RS05205	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HHJ60_RS05210	ENOG41090HJ	UPF0265 protein
HHJ60_RS05220	ENOG4105C5Y	PTS System
HHJ60_RS05225	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HHJ60_RS05230	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HHJ60_RS05235	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HHJ60_RS05240	ENOG4105E4F	Isochorismate synthase
HHJ60_RS05245	ENOG4105CHM	Aminotransferase
HHJ60_RS05255	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HHJ60_RS05260	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HHJ60_RS05265	ENOG4105EE5	Membrane protein terC
HHJ60_RS05275	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HHJ60_RS05280	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HHJ60_RS05295	ENOG4105EN6	Membrane
HHJ60_RS05300	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HHJ60_RS05305	ENOG4105CFH	Aspartokinase
HHJ60_RS05310	ENOG4107RM6	sulfurtransferase
HHJ60_RS05315	ENOG4105CUC	YeeE YedE family protein
HHJ60_RS05320	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HHJ60_RS05335	ENOG4105D2M	Aldolase
HHJ60_RS05340	ENOG4105CE4	GlcNAc 6-P deacetylase
HHJ60_RS05345	ENOG4105E98	transcriptional regulator DeoR family
HHJ60_RS05355	ENOG4105ENH	Sulfatase
HHJ60_RS05360	ENOG4105C4X	radical SAM domain protein
HHJ60_RS05375	ENOG4105DAS	pts system
HHJ60_RS05380	ENOG4105F3R	pts system mannose fructose sorbose family iid
HHJ60_RS05385	ENOG4105ETZ	PTS System
HHJ60_RS05390	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HHJ60_RS05395	ENOG4105E70	isomerase
HHJ60_RS05400	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HHJ60_RS05405	ENOG4105CBG	Sulfatase
HHJ60_RS05415	ENOG4105CHR	reductase
HHJ60_RS05425	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HHJ60_RS05430	ENOG4108UHU	Aldolase
HHJ60_RS05435	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HHJ60_RS05440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS05450	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HHJ60_RS05470	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HHJ60_RS05475	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HHJ60_RS05480	ENOG4108UBT	opacity-associated protein
HHJ60_RS05485	ENOG4105DH7	May be involved in recombination (By similarity)
HHJ60_RS05490	ENOG4105II7	pyrroline-5-carboxylate reductase
HHJ60_RS05495	ENOG4105D8G	Major Facilitator superfamily
HHJ60_RS05500	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HHJ60_RS05505	ENOG4105CQC	Prephenate dehydratase
HHJ60_RS05525	ENOG4105EMU	Dehydrogenase
HHJ60_RS05540	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHJ60_RS05545	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HHJ60_RS05550	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HHJ60_RS05555	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HHJ60_RS05560	ENOG4105CPF	Cell wall formation (By similarity)
HHJ60_RS05565	ENOG4105DFU	Cell wall formation (By similarity)
HHJ60_RS05570	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HHJ60_RS05575	ENOG4105CNI	cell division protein FtsW
HHJ60_RS05580	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HHJ60_RS05585	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HHJ60_RS05590	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HHJ60_RS05595	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HHJ60_RS05600	ENOG4105CJN	penicillin-binding protein
HHJ60_RS05610	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HHJ60_RS05615	ENOG4108V6E	Cell division protein mraZ
HHJ60_RS05635	ENOG4105C9A	Phoh family
HHJ60_RS05645	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HHJ60_RS05650	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HHJ60_RS05655	ENOG4105E7A	Glutamine amidotransferase
HHJ60_RS05660	ENOG4105C44	Serine transporter
HHJ60_RS05665	ENOG4105EJQ	L-serine dehydratase
HHJ60_RS05670	ENOG4105DA4	cytochrome c-type biogenesis protein
HHJ60_RS05675	ENOG4107QX9	Thiol disulfide interChange protein
HHJ60_RS05680	ENOG4108DMF	Cytochrome C biogenesis protein
HHJ60_RS05685	ENOG4108DMF	Cytochrome C biogenesis protein
HHJ60_RS05690	ENOG4105CBX	hi0933 family
HHJ60_RS05695	ENOG4105C0B	DNA polymerase III (alpha subunit)
HHJ60_RS05700	ENOG4105DVI	reductase, NrfD
HHJ60_RS05705	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HHJ60_RS05710	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
HHJ60_RS05715	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HHJ60_RS05720	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HHJ60_RS05735	ENOG4105DZ1	carboxypeptidase
HHJ60_RS05740	ENOG4105K6T	rare lipoprotein A
HHJ60_RS05745	ENOG4105CNI	cell division protein FtsW
HHJ60_RS05750	ENOG4105CJN	penicillin-binding protein
HHJ60_RS05760	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HHJ60_RS05765	ENOG4105C1J	atp-dependent rna helicase
HHJ60_RS05770	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HHJ60_RS05775	ENOG4105F27	Major Facilitator
HHJ60_RS05785	ENOG4105DHP	deoxycytidine triphosphate deaminase
HHJ60_RS05795	ENOG4107RCV	ABC transporter, permease
HHJ60_RS05800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS05825	ENOG4105M2J	Glutaredoxin
HHJ60_RS05840	ENOG4108V0P	LemA family
HHJ60_RS05850	ENOG4105CQB	FAD linked oxidase domain protein
HHJ60_RS05855	ENOG4105KA0	thioesterase Superfamily protein
HHJ60_RS05865	ENOG4105EIF	outer membrane protein W
HHJ60_RS05880	ENOG4105NAU	thioesterase Superfamily protein
HHJ60_RS05885	ENOG4105K9H	YciI-like protein
HHJ60_RS05890	ENOG4107QIJ	Aconitate hydratase 2
HHJ60_RS05905	ENOG4105EFX	secretion protein, HlyD family
HHJ60_RS05910	ENOG4105KK7	inner membrane protein YiaW
HHJ60_RS05915	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HHJ60_RS05920	ENOG4105CHV	Transcription elongation factor NusA
HHJ60_RS05925	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HHJ60_RS05935	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
HHJ60_RS05940	ENOG4105BZG	amino acid carrier protein
HHJ60_RS05955	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HHJ60_RS05960	ENOG4105EYK	Phosphatidylglycerophosphatase B
HHJ60_RS05980	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HHJ60_RS05990	ENOG4108R6K	riboflavin synthase, subunit alpha
HHJ60_RS05995	ENOG4107QI1	Mate efflux family protein
HHJ60_RS06000	ENOG4105D9R	oxidoreductase
HHJ60_RS06005	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HHJ60_RS06010	ENOG4108VD1	dedA family
HHJ60_RS06015	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HHJ60_RS06020	ENOG4108YI8	ABC transporter
HHJ60_RS06025	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HHJ60_RS06030	ENOG4107Z6I	Thiamine biosynthesis protein
HHJ60_RS06035	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HHJ60_RS06040	ENOG41085JB	UPF0434 protein
HHJ60_RS06045	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HHJ60_RS06050	ENOG4105BZ1	(ABC) transporter
HHJ60_RS06055	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HHJ60_RS06060	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HHJ60_RS06065	ENOG4105DWF	phosphomethylpyrimidine kinase
HHJ60_RS06070	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HHJ60_RS06075	ENOG4105K3M	)-transporter
HHJ60_RS06080	ENOG4108BMY	protease
HHJ60_RS06085	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HHJ60_RS06090	ENOG4105I7R	Adenylate cyclase
HHJ60_RS06095	ENOG4107IX6	phosphate transport regulator
HHJ60_RS06100	ENOG4105CJ3	phosphate transporter
HHJ60_RS06105	ENOG41077A9	carbonic anhydrase
HHJ60_RS06110	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HHJ60_RS06115	ENOG4105CGF	Aromatic amino acid aminotransferase
HHJ60_RS06120	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HHJ60_RS06125	ENOG4107VHA	regulatoR
HHJ60_RS06130	ENOG4105C6Z	Gluconate
HHJ60_RS06135	ENOG4105BZW	Glycerate kinase
HHJ60_RS06160	ENOG4108TIT	dATP pyrophosphohydrolase
HHJ60_RS06225	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HHJ60_RS06230	ENOG4105CDU	Replicative dna helicase
HHJ60_RS06235	ENOG4105NBI	YecM protein
HHJ60_RS06245	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS06250	ENOG4105E0C	molybdate abc transporter
HHJ60_RS06255	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HHJ60_RS06260	ENOG4105F4R	Transcriptional regulator mode
HHJ60_RS06265	ENOG4105D6U	Sodium Glutamate Symporter
HHJ60_RS06290	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HHJ60_RS06295	ENOG4107T0D	ABC, transporter
HHJ60_RS06300	ENOG4106SMU	thiamine transporter membrane protein
HHJ60_RS06305	ENOG4105DP9	ABC transporter
HHJ60_RS06310	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HHJ60_RS06315	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HHJ60_RS06320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS06325	ENOG4105F38	ABC transporter, permease
HHJ60_RS06330	ENOG4105D38	putrescine abc transporter
HHJ60_RS06335	ENOG4107RUE	extracellular solute-binding protein family 1
HHJ60_RS06345	ENOG4105KVH	Transcriptional regulator
HHJ60_RS06350	ENOG4105C6K	Malic enzyme
HHJ60_RS06360	ENOG4105CK5	oxidoreductase
HHJ60_RS06370	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
HHJ60_RS06385	ENOG4107EJG	GntR family transcriptional regulator
HHJ60_RS06390	ENOG4105CK5	oxidoreductase
HHJ60_RS06400	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HHJ60_RS06405	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HHJ60_RS06410	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HHJ60_RS06415	ENOG4105EJ9	Membrane
HHJ60_RS06420	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HHJ60_RS06430	ENOG4105EGS	Mechanosensitive ion channel
HHJ60_RS06435	ENOG4105CEY	Amp-dependent synthetase and ligase
HHJ60_RS06440	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HHJ60_RS06445	ENOG4105EV9	Alpha Beta Hydrolase
HHJ60_RS06450	ENOG4105NNH	LexA regulated protein
HHJ60_RS06455	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HHJ60_RS06460	ENOG41090R7	Ferric uptake
HHJ60_RS06465	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HHJ60_RS06470	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHJ60_RS06490	ENOG4105EMU	Dehydrogenase
HHJ60_RS06515	ENOG4105C2C	drug resistance transporter, Bcr CflA
HHJ60_RS06530	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HHJ60_RS06535	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HHJ60_RS06540	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HHJ60_RS06565	ENOG4107YB6	acetyltransferase, (GNAT) family
HHJ60_RS06570	ENOG4105MYG	DNA polymerase iii, chi subunit
HHJ60_RS06575	ENOG4105C9Q	fumarate hydratase class II
HHJ60_RS06580	ENOG4105CRQ	synthase (Component I)
HHJ60_RS06585	ENOG4105DDQ	anthranilate synthase
HHJ60_RS06590	ENOG4108V5Q	transglutaminase-like protein
HHJ60_RS06595	ENOG4107QYG	anthranilate phosphoribosyltransferase
HHJ60_RS06600	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HHJ60_RS06615	ENOG4105KWI	UPF0339 protein
HHJ60_RS06625	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HHJ60_RS06630	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HHJ60_RS06645	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HHJ60_RS06650	ENOG4105DFP	Integrase
HHJ60_RS06685	ENOG4106050	phage regulatory protein, rha family
HHJ60_RS06710	ENOG4105NVB	glycoside hydrolase, family 19
HHJ60_RS06735	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HHJ60_RS06895	ENOG4106CVF	DNA replication protein
HHJ60_RS06920	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HHJ60_RS06940	ENOG4107EPN	Domain of unknown function (DUF1508)
HHJ60_RS06990	ENOG4108UUM	single-stranded DNA-binding protein
HHJ60_RS07005	ENOG4105DH7	May be involved in recombination (By similarity)
HHJ60_RS07050	ENOG4105NI8	Cytosine-specific methyltransferase
HHJ60_RS07070	ENOG4108VTV	Inherit from NOG: Membrane
HHJ60_RS07075	ENOG4105M4H	endoribonuclease L-psp
HHJ60_RS07085	ENOG4105EEQ	Na H antiporter
HHJ60_RS07090	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HHJ60_RS07160	ENOG4105CXN	decarboxylase
HHJ60_RS07165	ENOG4105D5Q	Arginine ornithine antiporter
HHJ60_RS07175	ENOG4105C59	p-type ATPase
HHJ60_RS07185	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HHJ60_RS07195	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HHJ60_RS07200	ENOG4108MG3	formate dehydrogenase
HHJ60_RS07205	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HHJ60_RS07215	ENOG4105UGU	tonB-dependent Receptor
HHJ60_RS07220	ENOG4105KMT	branched-chain amino acid
HHJ60_RS07225	ENOG4108UMN	azlc family
HHJ60_RS07230	ENOG4105DZ2	Transcriptional regulator
HHJ60_RS07235	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HHJ60_RS07240	ENOG4105C8P	)-transporter
HHJ60_RS07250	ENOG4105CQ7	ATP-dependent helicase
HHJ60_RS07255	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HHJ60_RS07260	ENOG41082NX	50s ribosomal protein l35
HHJ60_RS07265	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HHJ60_RS07270	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HHJ60_RS07280	ENOG4105FAV	ABC, transporter
HHJ60_RS07285	ENOG4105FDK	ABC transporter
HHJ60_RS07290	ENOG4105DR5	peptidase
HHJ60_RS07295	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HHJ60_RS07300	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HHJ60_RS07310	ENOG4105EZE	Cupin 4 family protein
HHJ60_RS07315	ENOG4105VDB	UPF0125 protein
HHJ60_RS07320	ENOG4108Z1B	Cyclase dehydrase
HHJ60_RS07325	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HHJ60_RS07330	ENOG4105C3G	gtp-binding protein
HHJ60_RS07340	ENOG4105D5Q	Arginine ornithine antiporter
HHJ60_RS07345	ENOG4108JU8	Transcriptional regulator
HHJ60_RS07350	ENOG4106K28	UPF0283 membrane protein
HHJ60_RS07355	ENOG4105CM6	amino acid regulated cytosolic protein
HHJ60_RS07360	ENOG4108EVY	peptide transport periplasmic protein
HHJ60_RS07370	ENOG4108EU3	peptide transport system, permease
HHJ60_RS07375	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HHJ60_RS07385	ENOG4105YK5	50S ribosomal protein L36
HHJ60_RS07390	ENOG4105NRA	50s ribosomal protein l31 type b
HHJ60_RS07405	ENOG4105MGM	doxx family
HHJ60_RS07410	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HHJ60_RS07420	ENOG4105C12	Phosphoribosylglycinamide synthetase
HHJ60_RS07425	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HHJ60_RS07430	ENOG41065U4	response regulator
HHJ60_RS07440	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HHJ60_RS07445	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HHJ60_RS07450	ENOG4108ZJT	translation initiation factor, Sui1
HHJ60_RS07460	ENOG4105CFV	Tetratricopeptide repeat protein
HHJ60_RS07465	ENOG4105Q4A	inner membrane protein yciS
HHJ60_RS07470	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HHJ60_RS07475	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HHJ60_RS07480	ENOG4105CAT	Cytidine monophosphate kinase
HHJ60_RS07490	ENOG4107RAN	Peptidase, M16
HHJ60_RS07495	ENOG4108MJ5	VirK protein
HHJ60_RS07500	ENOG4105CDH	Citrulline--aspartate ligase
HHJ60_RS07505	ENOG4107SRH	Nad-dependent epimerase dehydratase
HHJ60_RS07520	ENOG4105C8V	SAICAR synthetase
HHJ60_RS07525	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HHJ60_RS07530	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HHJ60_RS07535	ENOG4105CE9	30S ribosomal protein S2
HHJ60_RS07540	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HHJ60_RS07545	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HHJ60_RS07550	ENOG4105DC8	reductase
HHJ60_RS07555	ENOG4105D6S	protein involved in catabolism of external DNA
HHJ60_RS07560	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HHJ60_RS07565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HHJ60_RS07570	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHJ60_RS07575	ENOG4105C0A	alcohol dehydrogenase
HHJ60_RS07580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HHJ60_RS07585	ENOG4105E55	glycerol-3-phosphate acyltransferase
HHJ60_RS07590	ENOG41065S8	Opacity family porin protein
HHJ60_RS07600	ENOG4105CQ0	ABC transporter
HHJ60_RS07605	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HHJ60_RS07615	ENOG4105E7U	AraC family transcriptional regulator
HHJ60_RS07625	ENOG4105BZG	amino acid carrier protein
HHJ60_RS07645	ENOG4105D7Q	type ii secretion system
HHJ60_RS07650	ENOG4105DAS	pts system
HHJ60_RS07655	ENOG4105ETZ	PTS System
HHJ60_RS07660	ENOG4105F3R	pts system mannose fructose sorbose family iid
HHJ60_RS07665	ENOG4108NK4	UPF0266 membrane protein
HHJ60_RS07670	ENOG4105EIP	mannose-6-phosphate isomerase
HHJ60_RS07675	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HHJ60_RS07680	ENOG4107RZZ	dna polymerase iii epsilon subunit
HHJ60_RS07695	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HHJ60_RS07700	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HHJ60_RS07705	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HHJ60_RS07710	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HHJ60_RS07720	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HHJ60_RS07725	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HHJ60_RS07730	ENOG4105C8T	Leucyl-tRNA synthetase
HHJ60_RS07740	ENOG4105DJF	DNA polymerase III, delta' subunit
HHJ60_RS07750	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HHJ60_RS07760	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHJ60_RS07765	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HHJ60_RS07770	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HHJ60_RS07780	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ60_RS07785	ENOG4105DZP	Membrane-associated zinc metalloprotease
HHJ60_RS07790	ENOG4105KNE	Phosphatidate cytidylyltransferase
HHJ60_RS07795	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HHJ60_RS07800	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HHJ60_RS07805	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HHJ60_RS07810	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HHJ60_RS07815	ENOG4107QHF	type ii secretion system protein e
HHJ60_RS07825	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HHJ60_RS07835	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HHJ60_RS07840	ENOG4105HF0	Membrane
HHJ60_RS07845	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HHJ60_RS07855	ENOG4108Z6B	deaminase
HHJ60_RS07860	ENOG4105CE4	GlcNAc 6-P deacetylase
HHJ60_RS07865	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HHJ60_RS07880	ENOG41084CK	capsule polysaccharide
HHJ60_RS07885	ENOG4105E12	capsule polysaccharide
HHJ60_RS07940	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HHJ60_RS07945	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HHJ60_RS07950	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HHJ60_RS07955	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HHJ60_RS08020	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
HHJ60_RS08105	ENOG4108N0N	Phage Terminase Large Subunit
HHJ60_RS08110	ENOG41061CV	Terminase small subunit 
HHJ60_RS08160	ENOG4105WXW	Antirepressor
HHJ60_RS08165	ENOG4105NY2	NinB protein
HHJ60_RS08245	ENOG41061CV	Terminase small subunit 
HHJ60_RS08250	ENOG4108N0N	Phage Terminase Large Subunit
HHJ60_RS08255	ENOG4107ZQ5	Phage-associated protein, HI1409 family
HHJ60_RS08260	ENOG4108C66	Inherit from COG: DNA primase
HHJ60_RS08270	ENOG41090AG	Bacteriophage protein
HHJ60_RS08315	ENOG4106GZK	Protein of unknown function (DUF2669)
HHJ60_RS08415	ENOG4105CWC	Acetylornithine deacetylase
HHJ60_RS08420	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HHJ60_RS08425	ENOG4105CAS	nag kinase
HHJ60_RS08430	ENOG4105CH7	arginosuccinase
HHJ60_RS08445	ENOG4105DHQ	Histidine kinase
HHJ60_RS08450	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HHJ60_RS08460	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HHJ60_RS08470	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HHJ60_RS08475	ENOG4105DTN	riboflavin biosynthesis protein ribF
HHJ60_RS08490	ENOG4108RMU	ferritin dps family protein
HHJ60_RS08495	ENOG4105DDQ	anthranilate synthase
HHJ60_RS08500	ENOG4105CRQ	synthase (Component I)
HHJ60_RS08525	ENOG4105KME	endoribonuclease L-psp
HHJ60_RS08535	ENOG4105DJV	ribulose-phosphate 3-epimerase
HHJ60_RS08540	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HHJ60_RS08545	ENOG4105C31	Tryptophanyl-tRNA synthetase
HHJ60_RS08550	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HHJ60_RS08560	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HHJ60_RS08565	ENOG4105E98	transcriptional regulator DeoR family
HHJ60_RS08570	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HHJ60_RS08575	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
HHJ60_RS08580	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HHJ60_RS08585	ENOG4105CXY	transporter
HHJ60_RS08590	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HHJ60_RS08595	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHJ60_RS08600	ENOG4106H78	methyltransferase
HHJ60_RS08605	ENOG4105C79	DNA protecting protein DprA
HHJ60_RS08610	ENOG41090FY	type IV pilus biogenesis stability protein PilW
HHJ60_RS08620	ENOG4105DSF	transport protein
HHJ60_RS08625	ENOG4108YZA	Nitrogen regulatory protein pii
HHJ60_RS08630	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HHJ60_RS08635	ENOG4108HPI	phosphatidate Cytidylyltransferase
HHJ60_RS08645	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
HHJ60_RS08650	ENOG4107QWE	)-transporter
HHJ60_RS08655	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HHJ60_RS08660	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HHJ60_RS08665	ENOG4105CUT	histidyl-tRNA synthetase
HHJ60_RS08670	ENOG4105N21	Membrane
HHJ60_RS08675	ENOG4105PF3	O-Antigen polymerase
HHJ60_RS08690	ENOG4105C30	Nad-dependent epimerase dehydratase
HHJ60_RS08710	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HHJ60_RS08715	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HHJ60_RS08725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HHJ60_RS08730	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HHJ60_RS08740	ENOG4105KJB	cyd operon protein YbgE
HHJ60_RS08750	ENOG4107YD3	Thioesterase
HHJ60_RS08755	ENOG4105E02	MotA TolQ exbB proton channel
HHJ60_RS08775	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HHJ60_RS08810	ENOG4105DSY	exodeoxyribonuclease V, gamma
HHJ60_RS08815	ENOG4108K4B	hydrolase
HHJ60_RS08820	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HHJ60_RS08825	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HHJ60_RS08860	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HHJ60_RS08865	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HHJ60_RS08870	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HHJ60_RS08920	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HHJ60_RS08925	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HHJ60_RS08930	ENOG4108UMI	ABC transporter, permease
HHJ60_RS08935	ENOG4105D01	(LipO)protein
HHJ60_RS08940	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HHJ60_RS08945	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HHJ60_RS08950	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HHJ60_RS08955	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HHJ60_RS08965	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HHJ60_RS08975	ENOG4108M6U	Universal stress protein A
HHJ60_RS08980	ENOG4105DXN	mazG family
HHJ60_RS08985	ENOG4105DTR	rard protein
HHJ60_RS08990	ENOG4105EMY	transcriptional regulator
HHJ60_RS08995	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HHJ60_RS09000	ENOG4105CBG	Sulfatase
HHJ60_RS09010	ENOG4105CK7	Sodium proline symporter
HHJ60_RS09015	ENOG4105C5H	ABC transporter
HHJ60_RS09020	ENOG4106AFN	Lyase and sodium transporter (By similarity)
HHJ60_RS09025	ENOG4107QSA	Oxaloacetate decarboxylase
HHJ60_RS09030	ENOG4105D9Q	decarboxylase (Beta subunit)
HHJ60_RS09045	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HHJ60_RS09055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HHJ60_RS09080	ENOG4105CIN	aminoacyl-histidine dipeptidase
HHJ60_RS09090	ENOG4107QMH	DNA methylase
HHJ60_RS09100	ENOG4108YYD	acetyltransferase
HHJ60_RS09115	ENOG4105PGM	cation diffusion facilitator family transporter
HHJ60_RS09150	ENOG4105CXY	transporter
HHJ60_RS09155	ENOG4105ECY	inositol monophosphatase
HHJ60_RS09160	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HHJ60_RS09165	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HHJ60_RS09170	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HHJ60_RS09175	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HHJ60_RS09180	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HHJ60_RS09205	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HHJ60_RS09210	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HHJ60_RS09215	ENOG4105QTB	Flavodoxin
HHJ60_RS09225	ENOG4105CBT	Fructose-1,6-bisphosphatase
HHJ60_RS09230	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HHJ60_RS09240	ENOG4108JJ9	ABC, transporter
HHJ60_RS09245	ENOG4105BZ1	(ABC) transporter
HHJ60_RS09250	ENOG4105CA0	peroxidase
HHJ60_RS09260	ENOG4105C8J	)-transporter
HHJ60_RS09265	ENOG4105E2X	shikimate dehydrogenase
HHJ60_RS09270	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HHJ60_RS09275	ENOG4108WI1	Dna topoisomerase
HHJ60_RS09280	ENOG4108Z03	MAF-like protein
HHJ60_RS09285	ENOG4105CGY	Dna recombination protein
HHJ60_RS09290	ENOG4108TEB	UPF0114 protein
HHJ60_RS09325	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HHJ60_RS09335	ENOG4105T16	Transcriptional regulator (AraC family)
HHJ60_RS09340	ENOG4105CMG	Carbohydrate kinase
HHJ60_RS09345	ENOG4105C93	Xylose Isomerase
HHJ60_RS09350	ENOG4105CHM	Aminotransferase
HHJ60_RS09355	ENOG4105DFD	Na H antiporter
HHJ60_RS09360	ENOG4107QTF	adenylosuccinate lyase
HHJ60_RS09365	ENOG41075W9	High frequency lysogenization protein HflD homolog
HHJ60_RS09375	ENOG410804X	Transcriptional regulator
HHJ60_RS09380	ENOG4105J92	DNA-binding transcriptional activator GutM
HHJ60_RS09385	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
HHJ60_RS09390	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HHJ60_RS09395	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HHJ60_RS09400	ENOG410787A	Pts system, glucitol sorbitol-specific
HHJ60_RS09405	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HHJ60_RS09410	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HHJ60_RS09415	ENOG4108UJU	UPF0301 protein
HHJ60_RS09425	ENOG4108HWW	ABC transporter
HHJ60_RS09430	ENOG4105C2J	ABC transporter
HHJ60_RS09435	ENOG4105DFW	ABC transporter
HHJ60_RS09440	ENOG4105CEN	a g-specific adenine glycosylase
HHJ60_RS09445	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HHJ60_RS09450	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HHJ60_RS09465	ENOG4107QUT	magnesium and cobalt transport protein CorA
HHJ60_RS09470	ENOG4108VIA	integral membrane protein
HHJ60_RS09475	ENOG4105VZ9	UPF0235 protein
HHJ60_RS09480	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HHJ60_RS09485	ENOG4105CAK	Cell division ATP-binding protein ftsE
HHJ60_RS09490	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HHJ60_RS09495	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HHJ60_RS09500	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HHJ60_RS09505	ENOG4105CMG	Carbohydrate kinase
HHJ60_RS09510	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HHJ60_RS09515	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HHJ60_RS09520	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HHJ60_RS09525	ENOG4108R66	Conserved Protein
HHJ60_RS09530	ENOG4105DG4	malate L-lactate dehydrogenase
HHJ60_RS09535	ENOG41069M3	Transcriptional regulator
HHJ60_RS09540	ENOG4105K5B	UPF0225 protein
HHJ60_RS09545	ENOG4107S2Z	UPF0761 membrane protein
HHJ60_RS09555	ENOG4105WH1	Two component transcriptional regulator luxr family
HHJ60_RS09560	ENOG4107T0K	Adenylate cyclase
HHJ60_RS09565	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HHJ60_RS09575	ENOG4105ECF	c-methyltransferase
HHJ60_RS09580	ENOG410601J	HemY protein
HHJ60_RS09585	ENOG4108ZPB	UPF0306 protein
HHJ60_RS09590	ENOG4108JPW	Aminotransferase
HHJ60_RS09595	ENOG4105DY8	decarboxylase
HHJ60_RS09600	ENOG4105C0P	Mg chelatase subunit ChlI
HHJ60_RS09605	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HHJ60_RS09610	ENOG41090ED	Protein with unknown function (DUF469)
HHJ60_RS09615	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HHJ60_RS09620	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HHJ60_RS09625	ENOG4105EI2	Pseudouridine synthase
HHJ60_RS09630	ENOG4105C03	ribonuclease
HHJ60_RS09640	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HHJ60_RS09645	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HHJ60_RS09650	ENOG4108IPT	Naphthoate synthase
HHJ60_RS09660	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HHJ60_RS09670	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HHJ60_RS09675	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HHJ60_RS09680	ENOG4105RG0	Membrane
HHJ60_RS09685	ENOG4108IA2	Sodium pantothenate symporter
HHJ60_RS09695	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HHJ60_RS09700	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HHJ60_RS09705	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HHJ60_RS09710	ENOG4108R99	pseudouridine synthase
HHJ60_RS09720	ENOG4105R3P	Inner membrane protein yagU
HHJ60_RS09725	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HHJ60_RS09730	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HHJ60_RS09735	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HHJ60_RS09740	ENOG4106BMH	cytolethal distending toxin
HHJ60_RS09745	ENOG4108TMH	cytolethal distending toxin
HHJ60_RS09755	ENOG4108VVK	transcriptional Regulator, AsnC
HHJ60_RS09780	ENOG4105C7B	Threonine dehydratase
HHJ60_RS09790	ENOG4105C01	Dihydroxy-acid dehydratase
HHJ60_RS09795	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HHJ60_RS09805	ENOG4105DQF	Hydrolase
HHJ60_RS09810	ENOG4107Z6W	Protein CrcB homolog
HHJ60_RS09815	ENOG4108EUD	Lysophospholipase
HHJ60_RS09820	ENOG4105EJ2	Transcriptional regulator
HHJ60_RS09825	ENOG4105C5Q	Transcriptional regulator
HHJ60_RS09830	ENOG4105EHV	domain protein
HHJ60_RS09840	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HHJ60_RS09845	ENOG4105WWK	YheO domain protein
HHJ60_RS09850	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HHJ60_RS09855	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HHJ60_RS09870	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HHJ60_RS09880	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HHJ60_RS09885	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HHJ60_RS09890	ENOG4105PM1	preprotein translocase subunit SecE
HHJ60_RS09895	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HHJ60_RS09915	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HHJ60_RS09920	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HHJ60_RS09925	ENOG4108VZM	50s ribosomal protein L10
HHJ60_RS09930	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HHJ60_RS09935	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHJ60_RS09940	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHJ60_RS09945	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HHJ60_RS09950	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HHJ60_RS09955	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HHJ60_RS09970	ENOG4105E68	Sulfatase
HHJ60_RS09980	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HHJ60_RS09985	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HHJ60_RS09990	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HHJ60_RS09995	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HHJ60_RS10000	ENOG4105DSJ	YicC domain protein
HHJ60_RS10005	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HHJ60_RS10010	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HHJ60_RS10020	ENOG4108Z33	Thiol disulfide Interchange Protein
HHJ60_RS10025	ENOG4108WFC	UPF0438 protein yifE
HHJ60_RS10030	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HHJ60_RS10035	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HHJ60_RS10040	ENOG4108VPT	UPF0234 protein
HHJ60_RS10045	ENOG4105EAC	phosphoserine phosphatase
HHJ60_RS10050	ENOG41062Z9	Membrane
HHJ60_RS10055	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HHJ60_RS10060	ENOG4105CJR	Integral membrane protein (MviN
HHJ60_RS10065	ENOG4105CFU	surface antigen
HHJ60_RS10070	ENOG4105MA0	exported protein
HHJ60_RS10075	ENOG4105C9X	ppx gppa phosphatase
HHJ60_RS10085	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HHJ60_RS10100	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HHJ60_RS10105	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HHJ60_RS10110	ENOG4105C34	Pseudouridine synthase
HHJ60_RS10115	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HHJ60_RS10120	ENOG4105D7A	ATP-binding protein
HHJ60_RS10125	ENOG4108MJ5	VirK protein
HHJ60_RS10135	ENOG4105BZU	Histidine kinase
HHJ60_RS10135	ENOG4105BZU	Histidine kinase
HHJ60_RS10140	ENOG4108YZA	Nitrogen regulatory protein pii
HHJ60_RS10145	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HHJ60_RS10150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HHJ60_RS10155	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HHJ60_RS10160	ENOG410903C	(LipO)protein
HHJ60_RS10170	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HHJ60_RS10175	ENOG4105C1J	atp-dependent rna helicase
HHJ60_RS10180	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HHJ60_RS10185	ENOG4105EZR	dyp-type peroxidase family protein
HHJ60_RS10195	ENOG4105ECY	inositol monophosphatase
HHJ60_RS10200	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HHJ60_RS10205	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HHJ60_RS10210	ENOG4105C3J	Cysteine desulfurase
HHJ60_RS10215	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HHJ60_RS10220	ENOG4108Z4V	iron-sulfur cluster assembly
HHJ60_RS10225	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HHJ60_RS10230	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HHJ60_RS10235	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HHJ60_RS10240	ENOG4108ZIT	Ferredoxin, 2FE-2S
HHJ60_RS10245	ENOG4105D9M	gamma-glutamylcysteine synthetase
HHJ60_RS10255	ENOG4105F3R	pts system mannose fructose sorbose family iid
HHJ60_RS10260	ENOG4105ETZ	PTS System
HHJ60_RS10265	ENOG4105DAS	pts system
HHJ60_RS10270	ENOG410667J	hydrolase
HHJ60_RS10275	ENOG4106WTF	Glycosyl transferase, family 2
HHJ60_RS10280	ENOG4105M5K	heptosyltransferase
HHJ60_RS10285	ENOG4105K5M	30s ribosomal protein S16
HHJ60_RS10290	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HHJ60_RS10300	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HHJ60_RS10305	ENOG4105E0M	Sulfatase
HHJ60_RS10310	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HHJ60_RS10315	ENOG4105C6K	Malic enzyme
HHJ60_RS10320	ENOG4105I08	Pseudouridine synthase
HHJ60_RS10325	ENOG4105C2C	drug resistance transporter, Bcr CflA
HHJ60_RS10330	ENOG4108Z6Z	Transcriptional regulator
HHJ60_RS10335	ENOG4105DIJ	Phosphoethanolamine transferase
HHJ60_RS10340	ENOG4105F9E	Shikimate 5-dehydrogenase
HHJ60_RS10345	ENOG4105D7W	serine acetyltransferase
HHJ60_RS10350	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HHJ60_RS10360	ENOG4107YZP	Rhodanese domain protein
HHJ60_RS10365	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HHJ60_RS10370	ENOG4108RCM	Nitroreductase
HHJ60_RS10380	ENOG4105JIM	Phosphatidylserine synthase
HHJ60_RS10385	ENOG4105EIB	trna rrna methyltransferase
HHJ60_RS10390	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HHJ60_RS10395	ENOG41083KI	ribonuclease, T2
HHJ60_RS10400	ENOG4105BZA	Phosphoglycerate kinase
HHJ60_RS10405	ENOG4105D2N	Aldolase
HHJ60_RS10415	ENOG4105D7K	pfkb domain protein
HHJ60_RS10420	ENOG4105CEP	NADH dehydrogenase
HHJ60_RS10425	ENOG4107R3N	Filamentation induced by cAMP protein fic
HHJ60_RS10435	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HHJ60_RS10440	ENOG4105C1A	potassium transporter peripheral membrane
HHJ60_RS10445	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HHJ60_RS10455	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HHJ60_RS10460	ENOG4105C1J	atp-dependent rna helicase
HHJ60_RS10465	ENOG4105RT1	May be involved in cell division (By similarity)
HHJ60_RS10475	ENOG4105CUW	cytochrome C-TYPE protein
HHJ60_RS10480	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HHJ60_RS10485	ENOG4105GXZ	Ferredoxin-type protein NapH
HHJ60_RS10490	ENOG4108BGM	Quinol dehydrogenase periplasmic component
HHJ60_RS10505	ENOG4105BZU	Histidine kinase
HHJ60_RS10510	ENOG4105D4A	Cell wall formation (By similarity)
HHJ60_RS10520	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HHJ60_RS10525	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HHJ60_RS10530	ENOG4105MJ2	Competence protein
HHJ60_RS10535	ENOG4105PXI	polysaccharide deacetylase
HHJ60_RS10540	ENOG41063SB	peptidase
HHJ60_RS10545	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HHJ60_RS10550	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HHJ60_RS10555	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HHJ60_RS10560	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HHJ60_RS10565	ENOG4108RR8	protoporphyrinogen oxidase
HHJ60_RS10595	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HHJ60_RS10600	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHJ60_RS10610	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HHJ60_RS10615	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HHJ60_RS10620	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HHJ60_RS10625	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HHJ60_RS10640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HHJ60_RS10645	ENOG41067V7	50S ribosomal protein L36
HHJ60_RS10650	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHJ60_RS10655	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HHJ60_RS10660	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HHJ60_RS10665	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HHJ60_RS10670	ENOG4108ZT0	50S ribosomal protein l17
HHJ60_RS10680	ENOG4105W0Z	cytoplasmic protein
HHJ60_RS10685	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HHJ60_RS10690	ENOG4108VVQ	metallophosphoesterase
HHJ60_RS10700	ENOG4105DFP	Integrase
HHJ60_RS10780	ENOG4105DZR	Type I site-specific deoxyribonuclease
HHJ60_RS10795	ENOG4105EKX	Restriction modification system DNA (Specificity
HHJ60_RS10805	ENOG4105IEY	(LipO)protein
HHJ60_RS10810	ENOG4105M85	Bola protein
HHJ60_RS10820	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHJ60_RS10825	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHJ60_RS10830	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHJ60_RS10835	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HHJ60_RS10840	ENOG4108EGU	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HHJ60_RS10845	ENOG4105CJ2	(LipO)protein
HHJ60_RS10855	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HHJ60_RS10860	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HHJ60_RS10870	ENOG4105D6U	Sodium Glutamate Symporter
HHJ60_RS10900	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HHJ60_RS10905	ENOG4105E09	nadh pyrophosphatase
HHJ60_RS10910	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HHJ60_RS10915	ENOG4105R2J	Conserved Protein
HHJ60_RS10920	ENOG4105K70	DNA-binding protein
HHJ60_RS10925	ENOG410804X	Transcriptional regulator
HHJ60_RS10930	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HHJ60_RS10945	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HHJ60_RS10950	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HHJ60_RS10955	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HHJ60_RS10960	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HHJ60_RS10965	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HHJ60_RS10970	ENOG41069PW	sigma-e factor negative regulatory protein
HHJ60_RS10975	ENOG4105EMN	RNA polymerase sigma factor
HHJ60_RS10980	ENOG4105Y75	tpr repeat protein
HHJ60_RS10990	ENOG4105DVA	methyltransferase
HHJ60_RS11015	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HHJ60_RS11020	ENOG4105KJF	protein tyrosine phosphatase
HHJ60_RS11025	ENOG4105BZ8	glutamate synthase
HHJ60_RS11030	ENOG4105CBC	glutamate synthase
HHJ60_RS11040	ENOG4105DKP	glycosyl transferase, family 9
HHJ60_RS11045	ENOG4105BZ1	(ABC) transporter
HHJ60_RS11050	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HHJ60_RS11055	ENOG4105C5B	carbamate kinase
HHJ60_RS11065	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HHJ60_RS11075	ENOG4107REC	cytoplasmic protein
HHJ60_RS11080	ENOG4107R1Q	Membrane protein FdrA
HHJ60_RS11090	ENOG4108NUU	Transcriptional regulator
HHJ60_RS11100	ENOG4107REC	cytoplasmic protein
HHJ60_RS11105	ENOG4107R1Q	Membrane protein FdrA
HHJ60_RS11110	ENOG4107SNB	ankyrin repeat protein YahD
HHJ60_RS11130	ENOG4108RS6	transposase
HHJ60_RS11135	ENOG4105D7V	transposase
HHJ60_RS11140	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HHJ60_RS11145	ENOG4105CDA	abc transporter atp-binding protein
HHJ60_RS11150	ENOG4105E5Q	amino acid AbC transporter
HHJ60_RS11155	ENOG4105EAB	amino acid AbC transporter
HHJ60_RS11160	ENOG4105D4P	Coproporphyrinogen iii oxidase
HHJ60_RS11165	ENOG4105XCT	Protein of unknown function (DUF2489)
HHJ60_RS11170	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HHJ60_RS11175	ENOG4105D3G	Pseudouridine synthase
HHJ60_RS11180	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HHJ60_RS11190	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HHJ60_RS11200	ENOG4105C26	Dehydrogenase
HHJ60_RS11205	ENOG4105DH8	myo-inositol catabolism
HHJ60_RS11220	ENOG4108HYK	gCN5-related N-acetyltransferase
HHJ60_RS11250	ENOG4105EDR	glucose galactose transporter
HHJ60_RS11255	ENOG4107W7X	Aldolase
HHJ60_RS11265	ENOG4105CMG	Carbohydrate kinase
HHJ60_RS11270	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
HHJ60_RS11275	ENOG4107EDW	L-fucose operon activator
HHJ60_RS11280	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HHJ60_RS11285	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HHJ60_RS11300	ENOG4105XA0	heptosyltransferase ii
HHJ60_RS11305	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HHJ60_RS11310	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHJ60_RS11315	ENOG4107104	thymidine kinase
HHJ60_RS11335	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HHJ60_RS11340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HHJ60_RS11355	ENOG4105KZW	UPF0381 protein
HHJ60_RS11360	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HHJ60_RS11365	ENOG41060A7	DNA polymerase beta domain protein region
HHJ60_RS11370	ENOG41062MS	nucleotidyltransferase substrate binding protein
HHJ60_RS11375	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HHJ60_RS11380	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HHJ60_RS11385	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HHJ60_RS11390	ENOG4105EPD	Oligopeptide transporter, Opt family
HHJ60_RS11395	ENOG4105VEJ	Heat shock protein
HHJ60_RS11400	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HHJ60_RS11405	ENOG4105ETE	Transcriptional regulator (LacI family
HHJ60_RS11420	ENOG4105CMG	Carbohydrate kinase
HHJ60_RS11425	ENOG4105C2J	ABC transporter
HHJ60_RS11430	ENOG4105CNN	ABC, transporter
HHJ60_RS11435	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HHJ60_RS11445	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HHJ60_RS11455	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HHJ60_RS11460	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HHJ60_RS11465	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HHJ60_RS11470	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHJ60_RS11475	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HHJ60_RS11485	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HHJ60_RS11490	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HHJ60_RS11495	ENOG41083MP	50s ribosomal protein l29
HHJ60_RS11500	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HHJ60_RS11510	ENOG4105DFP	Integrase
HHJ60_RS11600	ENOG41061CV	Terminase small subunit 
HHJ60_RS11670	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHJ60_RS11675	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HHJ60_RS11680	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)