locus-tag	class	description
VY92_RS00005	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
VY92_RS00010	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
VY92_RS00020	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VY92_RS00025	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VY92_RS00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VY92_RS00035	ENOG4105EX9	Membrane
VY92_RS00040	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
VY92_RS00045	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VY92_RS00050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VY92_RS00055	ENOG41080IJ	Diacylglycerol kinase
VY92_RS00060	ENOG4107RB3	L-asparaginase
VY92_RS00070	ENOG4107ZVW	dihydroneopterin aldolase
VY92_RS00075	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
VY92_RS00085	ENOG41066DY	Membrane
VY92_RS00090	ENOG4108ZMA	Outer membrane lipoprotein
VY92_RS00095	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
VY92_RS00100	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
VY92_RS00105	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
VY92_RS00110	ENOG4105EUB	pirin domain protein
VY92_RS00115	ENOG4108YYH	Nadph-dependent fmn reductase
VY92_RS00120	ENOG4108ETH	Formylglycinamide ribotide synthetase
VY92_RS00125	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
VY92_RS00130	ENOG4107S6X	Glycosyl transferase, family 2
VY92_RS00135	ENOG4105PF3	O-Antigen polymerase
VY92_RS00140	ENOG4105N21	Membrane
VY92_RS00145	ENOG4105CUT	histidyl-tRNA synthetase
VY92_RS00150	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
VY92_RS00155	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
VY92_RS00160	ENOG4107QWE	)-transporter
VY92_RS00165	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
VY92_RS00175	ENOG4108HPI	phosphatidate Cytidylyltransferase
VY92_RS00180	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
VY92_RS00185	ENOG4108YZA	Nitrogen regulatory protein pii
VY92_RS00190	ENOG4105DSF	transport protein
VY92_RS00200	ENOG41090FY	type IV pilus biogenesis stability protein PilW
VY92_RS00205	ENOG4105C79	DNA protecting protein DprA
VY92_RS00210	ENOG4106H78	methyltransferase
VY92_RS00215	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
VY92_RS00220	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
VY92_RS00225	ENOG4105CXY	transporter
VY92_RS00230	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
VY92_RS00235	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
VY92_RS00240	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VY92_RS00245	ENOG4105E98	transcriptional regulator DeoR family
VY92_RS00250	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
VY92_RS00260	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
VY92_RS00265	ENOG4105C31	Tryptophanyl-tRNA synthetase
VY92_RS00270	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VY92_RS00275	ENOG4105DJV	ribulose-phosphate 3-epimerase
VY92_RS00285	ENOG4105KME	endoribonuclease L-psp
VY92_RS00310	ENOG4105CRQ	synthase (Component I)
VY92_RS00315	ENOG4105DDQ	anthranilate synthase
VY92_RS00320	ENOG4108RMU	ferritin dps family protein
VY92_RS00335	ENOG4105DTN	riboflavin biosynthesis protein ribF
VY92_RS00340	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VY92_RS00350	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
VY92_RS00360	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VY92_RS00365	ENOG4105DHQ	Histidine kinase
VY92_RS00380	ENOG4105CH7	arginosuccinase
VY92_RS00385	ENOG4105CAS	nag kinase
VY92_RS00395	ENOG4105CWC	Acetylornithine deacetylase
VY92_RS00500	ENOG4106GZK	Protein of unknown function (DUF2669)
VY92_RS00545	ENOG41090AG	Bacteriophage protein
VY92_RS00555	ENOG4108C66	Inherit from COG: DNA primase
VY92_RS00560	ENOG4107ZQ5	Phage-associated protein, HI1409 family
VY92_RS00565	ENOG4108N0N	Phage Terminase Large Subunit
VY92_RS00570	ENOG41061CV	Terminase small subunit 
VY92_RS00620	ENOG4105WXW	Antirepressor
VY92_RS00625	ENOG4105NY2	NinB protein
VY92_RS00660	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VY92_RS00675	ENOG4107EPN	Domain of unknown function (DUF1508)
VY92_RS00730	ENOG4105WXW	Antirepressor
VY92_RS00735	ENOG4105NY2	NinB protein
VY92_RS00810	ENOG41061CV	Terminase small subunit 
VY92_RS00815	ENOG4108N0N	Phage Terminase Large Subunit
VY92_RS00900	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
VY92_RS01095	ENOG4105ED4	portal protein
VY92_RS01130	ENOG4105VZ1	Replication Protein
VY92_RS01170	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VY92_RS01175	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
VY92_RS01180	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VY92_RS01185	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
VY92_RS01190	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VY92_RS01250	ENOG4105E12	capsule polysaccharide
VY92_RS01255	ENOG41084CK	capsule polysaccharide
VY92_RS01270	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
VY92_RS01275	ENOG4105CE4	GlcNAc 6-P deacetylase
VY92_RS01280	ENOG4108Z6B	deaminase
VY92_RS01290	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VY92_RS01295	ENOG4105HF0	Membrane
VY92_RS01300	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
VY92_RS01310	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
VY92_RS01320	ENOG4107QHF	type ii secretion system protein e
VY92_RS01325	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
VY92_RS01330	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VY92_RS01335	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
VY92_RS01340	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VY92_RS01345	ENOG4105KNE	Phosphatidate cytidylyltransferase
VY92_RS01350	ENOG4105DZP	Membrane-associated zinc metalloprotease
VY92_RS01355	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VY92_RS01365	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VY92_RS01370	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VY92_RS01375	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VY92_RS01385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VY92_RS01395	ENOG4105DJF	DNA polymerase III, delta' subunit
VY92_RS01405	ENOG4105C8T	Leucyl-tRNA synthetase
VY92_RS01410	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
VY92_RS01415	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VY92_RS01425	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
VY92_RS01430	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
VY92_RS01435	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
VY92_RS01440	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VY92_RS01465	ENOG4107RZZ	dna polymerase iii epsilon subunit
VY92_RS01470	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VY92_RS01475	ENOG4105EIP	mannose-6-phosphate isomerase
VY92_RS01480	ENOG4108NK4	UPF0266 membrane protein
VY92_RS01485	ENOG4105F3R	pts system mannose fructose sorbose family iid
VY92_RS01490	ENOG4105ETZ	PTS System
VY92_RS01495	ENOG4105DAS	pts system
VY92_RS01500	ENOG4105D7Q	type ii secretion system
VY92_RS01520	ENOG4105BZG	amino acid carrier protein
VY92_RS01530	ENOG4105E7U	AraC family transcriptional regulator
VY92_RS01540	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VY92_RS01545	ENOG4105CQ0	ABC transporter
VY92_RS01555	ENOG41065S8	Opacity family porin protein
VY92_RS01560	ENOG4105E55	glycerol-3-phosphate acyltransferase
VY92_RS01565	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VY92_RS01570	ENOG4105C0A	alcohol dehydrogenase
VY92_RS01575	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VY92_RS01580	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VY92_RS01585	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VY92_RS01590	ENOG4105D6S	protein involved in catabolism of external DNA
VY92_RS01595	ENOG4105DC8	reductase
VY92_RS01600	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VY92_RS01605	ENOG4105EIN	peptidylprolyl cis-trans isomerase
VY92_RS01610	ENOG4105CE9	30S ribosomal protein S2
VY92_RS01615	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VY92_RS01620	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
VY92_RS01625	ENOG4105C8V	SAICAR synthetase
VY92_RS01640	ENOG4107SRH	Nad-dependent epimerase dehydratase
VY92_RS01645	ENOG4105CDH	Citrulline--aspartate ligase
VY92_RS01650	ENOG4108MJ5	VirK protein
VY92_RS01655	ENOG4107RAN	Peptidase, M16
VY92_RS01660	ENOG4105PE1	Receptor
VY92_RS01665	ENOG4105CAT	Cytidine monophosphate kinase
VY92_RS01670	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
VY92_RS01675	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VY92_RS01680	ENOG4105Q4A	inner membrane protein yciS
VY92_RS01685	ENOG4105CFV	Tetratricopeptide repeat protein
VY92_RS01695	ENOG4108ZJT	translation initiation factor, Sui1
VY92_RS01700	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VY92_RS01705	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
VY92_RS01715	ENOG41065U4	response regulator
VY92_RS01720	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VY92_RS01725	ENOG4105C12	Phosphoribosylglycinamide synthetase
VY92_RS01735	ENOG4105DC1	bifunctional purine biosynthesis protein purh
VY92_RS01740	ENOG4105MGM	doxx family
VY92_RS01745	ENOG4105EUR	Domain-Containing protein
VY92_RS01755	ENOG4105NRA	50s ribosomal protein l31 type b
VY92_RS01760	ENOG4105YK5	50S ribosomal protein L36
VY92_RS01770	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
VY92_RS01775	ENOG4108EU3	peptide transport system, permease
VY92_RS01785	ENOG4108EVY	peptide transport periplasmic protein
VY92_RS01790	ENOG4105CM6	amino acid regulated cytosolic protein
VY92_RS01795	ENOG4106K28	UPF0283 membrane protein
VY92_RS01800	ENOG4108JU8	Transcriptional regulator
VY92_RS01815	ENOG4105C3G	gtp-binding protein
VY92_RS01820	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
VY92_RS01825	ENOG4108Z1B	Cyclase dehydrase
VY92_RS01830	ENOG4105VDB	UPF0125 protein
VY92_RS01835	ENOG4105EZE	Cupin 4 family protein
VY92_RS01845	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
VY92_RS01850	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VY92_RS01855	ENOG4105DR5	peptidase
VY92_RS01860	ENOG4105FDK	ABC transporter
VY92_RS01865	ENOG4105FAV	ABC, transporter
VY92_RS01870	ENOG4105CFG	Acts as a chaperone (By similarity)
VY92_RS01875	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VY92_RS01880	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VY92_RS01885	ENOG41082NX	50s ribosomal protein l35
VY92_RS01890	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VY92_RS01895	ENOG4105CQ7	ATP-dependent helicase
VY92_RS01905	ENOG4105C8P	)-transporter
VY92_RS01910	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
VY92_RS01915	ENOG4105DZ2	Transcriptional regulator
VY92_RS01920	ENOG4108UMN	azlc family
VY92_RS01925	ENOG4105KMT	branched-chain amino acid
VY92_RS01930	ENOG4105UGU	tonB-dependent Receptor
VY92_RS01940	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
VY92_RS01945	ENOG4108MG3	formate dehydrogenase
VY92_RS01950	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VY92_RS01960	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VY92_RS01975	ENOG4105D5Q	Arginine ornithine antiporter
VY92_RS01980	ENOG4105CXN	decarboxylase
VY92_RS02055	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
VY92_RS02060	ENOG4105EEQ	Na H antiporter
VY92_RS02070	ENOG4105M4H	endoribonuclease L-psp
VY92_RS02075	ENOG4108VTV	Inherit from NOG: Membrane
VY92_RS02095	ENOG4105NI8	Cytosine-specific methyltransferase
VY92_RS02135	ENOG4105DH7	May be involved in recombination (By similarity)
VY92_RS02150	ENOG4108UUM	single-stranded DNA-binding protein
VY92_RS02195	ENOG4107EPN	Domain of unknown function (DUF1508)
VY92_RS02210	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VY92_RS02235	ENOG4106CVF	DNA replication protein
VY92_RS02400	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
VY92_RS02425	ENOG4105NVB	glycoside hydrolase, family 19
VY92_RS02450	ENOG4106050	phage regulatory protein, rha family
VY92_RS02485	ENOG4105DFP	Integrase
VY92_RS02490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VY92_RS02505	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VY92_RS02510	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
VY92_RS02520	ENOG4105KWI	UPF0339 protein
VY92_RS02535	ENOG4105DK0	Indole-3-glycerol phosphate synthase
VY92_RS02540	ENOG4107QYG	anthranilate phosphoribosyltransferase
VY92_RS02545	ENOG4108V5Q	transglutaminase-like protein
VY92_RS02550	ENOG4105DDQ	anthranilate synthase
VY92_RS02555	ENOG4105CRQ	synthase (Component I)
VY92_RS02560	ENOG4105C9Q	fumarate hydratase class II
VY92_RS02565	ENOG4105MYG	DNA polymerase iii, chi subunit
VY92_RS02570	ENOG4107YB6	acetyltransferase, (GNAT) family
VY92_RS02595	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VY92_RS02600	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
VY92_RS02605	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VY92_RS02620	ENOG4105C2C	drug resistance transporter, Bcr CflA
VY92_RS02640	ENOG4105EMU	Dehydrogenase
VY92_RS02660	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VY92_RS02665	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VY92_RS02670	ENOG41090R7	Ferric uptake
VY92_RS02675	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
VY92_RS02680	ENOG4105NNH	LexA regulated protein
VY92_RS02685	ENOG4105EV9	Alpha Beta Hydrolase
VY92_RS02690	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
VY92_RS02695	ENOG4105CEY	Amp-dependent synthetase and ligase
VY92_RS02700	ENOG4105EGS	Mechanosensitive ion channel
VY92_RS02710	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
VY92_RS02715	ENOG4105EJ9	Membrane
VY92_RS02720	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
VY92_RS02725	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
VY92_RS02730	ENOG4107QMP	dna polymerase iii subunits gamma and tau
VY92_RS02740	ENOG4105CK5	oxidoreductase
VY92_RS02745	ENOG4107EJG	GntR family transcriptional regulator
VY92_RS02760	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
VY92_RS02770	ENOG4105CK5	oxidoreductase
VY92_RS02780	ENOG4105C6K	Malic enzyme
VY92_RS02785	ENOG4105KVH	Transcriptional regulator
VY92_RS02795	ENOG4107RUE	extracellular solute-binding protein family 1
VY92_RS02800	ENOG4105D38	putrescine abc transporter
VY92_RS02805	ENOG4105F38	ABC transporter, permease
VY92_RS02810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VY92_RS02815	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VY92_RS02820	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
VY92_RS02825	ENOG4105DP9	ABC transporter
VY92_RS02830	ENOG4106SMU	thiamine transporter membrane protein
VY92_RS02835	ENOG4107T0D	ABC, transporter
VY92_RS02840	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
VY92_RS02865	ENOG4105D6U	Sodium Glutamate Symporter
VY92_RS02870	ENOG4105F4R	Transcriptional regulator mode
VY92_RS02875	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
VY92_RS02880	ENOG4105E0C	molybdate abc transporter
VY92_RS02885	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
VY92_RS02895	ENOG4105NBI	YecM protein
VY92_RS02900	ENOG4105CDU	Replicative dna helicase
VY92_RS02905	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VY92_RS02970	ENOG4108TIT	dATP pyrophosphohydrolase
VY92_RS02995	ENOG4105BZW	Glycerate kinase
VY92_RS03000	ENOG4105C6Z	Gluconate
VY92_RS03005	ENOG4107VHA	regulatoR
VY92_RS03010	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VY92_RS03015	ENOG4105CGF	Aromatic amino acid aminotransferase
VY92_RS03020	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VY92_RS03025	ENOG41077A9	carbonic anhydrase
VY92_RS03030	ENOG4105CJ3	phosphate transporter
VY92_RS03035	ENOG4107IX6	phosphate transport regulator
VY92_RS03040	ENOG4105I7R	Adenylate cyclase
VY92_RS03045	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
VY92_RS03050	ENOG4108BMY	protease
VY92_RS03055	ENOG4105K3M	)-transporter
VY92_RS03060	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
VY92_RS03065	ENOG4105DWF	phosphomethylpyrimidine kinase
VY92_RS03070	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
VY92_RS03075	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
VY92_RS03080	ENOG4105BZ1	(ABC) transporter
VY92_RS03085	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VY92_RS03090	ENOG41085JB	UPF0434 protein
VY92_RS03095	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VY92_RS03100	ENOG4107Z6I	Thiamine biosynthesis protein
VY92_RS03105	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
VY92_RS03110	ENOG4108YI8	ABC transporter
VY92_RS03115	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VY92_RS03120	ENOG4108VD1	dedA family
VY92_RS03125	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
VY92_RS03130	ENOG4105D9R	oxidoreductase
VY92_RS03135	ENOG4107QI1	Mate efflux family protein
VY92_RS03140	ENOG4108R6K	riboflavin synthase, subunit alpha
VY92_RS03150	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
VY92_RS03170	ENOG4105EYK	Phosphatidylglycerophosphatase B
VY92_RS03175	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
VY92_RS03190	ENOG4105BZG	amino acid carrier protein
VY92_RS03195	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
VY92_RS03205	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
VY92_RS03210	ENOG4105CHV	Transcription elongation factor NusA
VY92_RS03215	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VY92_RS03220	ENOG4105KK7	inner membrane protein YiaW
VY92_RS03225	ENOG4105EFX	secretion protein, HlyD family
VY92_RS03240	ENOG4107QIJ	Aconitate hydratase 2
VY92_RS03245	ENOG4105K9H	YciI-like protein
VY92_RS03250	ENOG4105NAU	thioesterase Superfamily protein
VY92_RS03265	ENOG4105EIF	outer membrane protein W
VY92_RS03275	ENOG4105KA0	thioesterase Superfamily protein
VY92_RS03280	ENOG4105CQB	FAD linked oxidase domain protein
VY92_RS03290	ENOG4108V0P	LemA family
VY92_RS03305	ENOG4105M2J	Glutaredoxin
VY92_RS03340	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VY92_RS03345	ENOG4105TWJ	Domain of unknown function (DUF1919)
VY92_RS03350	ENOG4105P4J	Allophanate hydrolase, subunit 1
VY92_RS03355	ENOG4107R7A	Allophanate hydrolase subunit 2
VY92_RS03360	ENOG4105E7W	lamb ycsf family protein
VY92_RS03365	ENOG4105C5A	transporter
VY92_RS03370	ENOG4105CFP	Peptidase U32
VY92_RS03380	ENOG4105SYT	Methylenetetrahydrofolate reductase
VY92_RS03390	ENOG4105CGK	Exodeoxyribonuclease III
VY92_RS03405	ENOG4105ERU	peptidase
VY92_RS03410	ENOG4105C4Y	ABC transporter
VY92_RS03415	ENOG4107RN3	metallophosphoesterase
VY92_RS03420	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VY92_RS03425	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VY92_RS03440	ENOG4105DVT	helicase
VY92_RS03445	ENOG41072GX	Peptidase M22 Glycoprotease
VY92_RS03450	ENOG4105CEY	Amp-dependent synthetase and ligase
VY92_RS03455	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
VY92_RS03470	ENOG4108JJ8	(ABC) transporter
VY92_RS03475	ENOG4108JJ9	ABC, transporter
VY92_RS03480	ENOG4105C3M	thioredoxin reductase
VY92_RS03485	ENOG4107QR8	Thioredoxin
VY92_RS03490	ENOG4105C6Z	Gluconate
VY92_RS03495	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
VY92_RS03500	ENOG4105C5H	ABC transporter
VY92_RS03505	ENOG4105C8J	)-transporter
VY92_RS03510	ENOG4105CSM	endonuclease III
VY92_RS03515	ENOG4105DZB	Electron transport complex
VY92_RS03520	ENOG4108UQQ	Electron transport complex
VY92_RS03525	ENOG4105D6A	Electron transport complex
VY92_RS03530	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
VY92_RS03535	ENOG4108R3D	Electron transport complex
VY92_RS03540	ENOG4105DGN	Electron transport complex
VY92_RS03545	ENOG4105ECP	epimerase
VY92_RS03550	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
VY92_RS03555	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VY92_RS03565	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
VY92_RS03570	ENOG4105C2X	Arabinose 5-phosphate isomerase
VY92_RS03580	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
VY92_RS03585	ENOG4108DG9	Smr protein MutS2
VY92_RS03590	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VY92_RS03595	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
VY92_RS03600	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
VY92_RS03615	ENOG4105VEQ	Cold shock protein
VY92_RS03630	ENOG4105DIQ	Transcriptional regulator
VY92_RS03635	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
VY92_RS03640	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
VY92_RS03645	ENOG4105DAN	ATP-dependent protease
VY92_RS03650	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
VY92_RS03655	ENOG4108Z66	YbaK ebsC protein
VY92_RS03660	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VY92_RS03665	ENOG4105C7N	Xanthine uracil vitamin C permease
VY92_RS03670	ENOG41090EX	DsrE family
VY92_RS03675	ENOG4107QKA	exodeoxyribonuclease V beta
VY92_RS03680	ENOG4107QYX	exodeoxyribonuclease v alpha
VY92_RS03690	ENOG4105C5S	asparaginyl-tRNA synthetase
VY92_RS03695	ENOG4105E2R	ROK family
VY92_RS03705	ENOG4105CIY	formyltetrahydrofolate deformylase
VY92_RS03710	ENOG4105CVJ	phosphoglycerate mutase
VY92_RS03715	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
VY92_RS03720	ENOG4108W1A	pseudouridine synthase
VY92_RS03735	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VY92_RS03740	ENOG4108QBX	(LipO)protein
VY92_RS03745	ENOG4108NSE	outer membrane autotransporter barrel
VY92_RS03760	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
VY92_RS03765	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
VY92_RS03775	ENOG4108TZV	Membrane
VY92_RS03780	ENOG4105CJB	Exodeoxyribonuclease I
VY92_RS03800	ENOG4105KB2	stringent starvation protein b
VY92_RS03805	ENOG4107MKT	Stringent starvation protein a
VY92_RS03820	ENOG4105DR9	pseudouridine synthase
VY92_RS03825	ENOG4105WP7	tRNA pseudouridine synthase C
VY92_RS03830	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
VY92_RS03845	ENOG4105EWT	decarboxylase family
VY92_RS03850	ENOG4105UKP	Protein of unknown function (DUF1778)
VY92_RS03860	ENOG4105K64	Glycosyl transferase, family 2
VY92_RS03865	ENOG4105E3A	(ABC) transporter
VY92_RS03870	ENOG4105DA5	(ABC) transporter
VY92_RS03875	ENOG4108BPE	-transporting atpase
VY92_RS03880	ENOG4105D0M	Protease HtpX homolog
VY92_RS03885	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VY92_RS03890	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VY92_RS03895	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VY92_RS03900	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VY92_RS03905	ENOG4108ESZ	Glycogen debranching enzyme
VY92_RS03910	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
VY92_RS03915	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
VY92_RS03920	ENOG4105KAF	membrAne
VY92_RS03925	ENOG4108ZZ3	UPF0260 protein
VY92_RS03930	ENOG4105CX6	glutaminyL-tRNA synthetase
VY92_RS03940	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VY92_RS03945	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VY92_RS03955	ENOG4107QN2	dihydrolipoyl dehydrogenase
VY92_RS03960	ENOG4107QSN	dihydrolipoamide acetyltransferase
VY92_RS03965	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
VY92_RS03970	ENOG4105C5Y	PTS System
VY92_RS03975	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
VY92_RS03980	ENOG4105KZ7	phosphocarrier protein hpr
VY92_RS03985	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VY92_RS03990	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
VY92_RS04005	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VY92_RS04010	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VY92_RS04015	ENOG4105D1H	recombination factor protein RarA
VY92_RS04030	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
VY92_RS04035	ENOG4105CNU	cell division protein FtsK
VY92_RS04040	ENOG4105EW9	transcriptional regulator AsnC family
VY92_RS04045	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
VY92_RS04050	ENOG41067MG	lrgb family
VY92_RS04055	ENOG4105VAW	lrga family
VY92_RS04060	ENOG4105KK6	nuclease
VY92_RS04065	ENOG4105C9B	Cysteine desulfurase
VY92_RS04070	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
VY92_RS04075	ENOG4105RHG	
VY92_RS04080	ENOG4105D0Y	UPF0227 protein
VY92_RS04085	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VY92_RS04090	ENOG41090BQ	Glutaredoxin
VY92_RS04095	ENOG4107QZM	n-acetylglutamate synthase
VY92_RS04110	ENOG4105DJ0	Poly(A) Polymerase
VY92_RS04115	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VY92_RS04120	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VY92_RS04130	ENOG4105CTB	Polyprenyl synthetase
VY92_RS04135	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VY92_RS04140	ENOG4105HBR	Rna-binding protein
VY92_RS04145	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VY92_RS04150	ENOG4105QVC	MOSC domain-containing protein
VY92_RS04160	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
VY92_RS04165	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VY92_RS04170	ENOG4105DB7	PHP domain protein
VY92_RS04175	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VY92_RS04180	ENOG4105CD8	aminopeptidase N
VY92_RS04185	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VY92_RS04230	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VY92_RS04235	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
VY92_RS04240	ENOG4105E96	Colicin v production protein
VY92_RS04245	ENOG4105PQ6	UPF0208 membrane protein
VY92_RS04250	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VY92_RS04255	ENOG4108DNC	Involved in acetate metabolism (By similarity)
VY92_RS04280	ENOG4105D64	Mechanosensitive ion channel
VY92_RS04285	ENOG4108K5H	permease YjgP YjgQ family protein
VY92_RS04290	ENOG4108M8S	permease YjgP YjgQ family protein
VY92_RS04295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VY92_RS04315	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VY92_RS04320	ENOG4105D1A	Methyltransferase
VY92_RS04325	ENOG4105DDY	UPF0142 protein ycaO
VY92_RS04330	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
VY92_RS04335	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VY92_RS04350	ENOG4105XPH	Ferredoxin
VY92_RS04360	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
VY92_RS04365	ENOG4108ZAI	phosphatidylglycerophosphatase a
VY92_RS04370	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
VY92_RS04375	ENOG4107YIM	Involved in the transcription termination process (By similarity)
VY92_RS04385	ENOG4105E0U	tyrosine-specific transport protein
VY92_RS04395	ENOG4108BY2	phosphohistidine phosphatase
VY92_RS04400	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VY92_RS04405	ENOG4105EEI	dihydropteroate synthase
VY92_RS04415	ENOG4105C0H	protease
VY92_RS04420	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VY92_RS04425	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VY92_RS04465	ENOG4105E9S	glutaredoxin 2
VY92_RS04505	ENOG4105DFP	Integrase
VY92_RS04525	ENOG4105W1T	Glycosyl Transferase
VY92_RS04530	ENOG4105W1T	Glycosyl Transferase
VY92_RS04550	ENOG4105D7X	high-affinity nickel-transporter
VY92_RS04555	ENOG41065CD	Exported protein
VY92_RS04560	ENOG4105C5H	ABC transporter
VY92_RS04565	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VY92_RS04575	ENOG4105ETE	Transcriptional regulator (LacI family
VY92_RS04580	ENOG4108RVA	ribokinase
VY92_RS04585	ENOG4105D9N	nucleoside
VY92_RS04590	ENOG4105DU0	nucleoside hydrolase
VY92_RS04595	ENOG4105C0H	protease
VY92_RS04600	ENOG4108MN8	Membrane
VY92_RS04605	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
VY92_RS04615	ENOG4105DIK	(ABC) transporter
VY92_RS04620	ENOG4105CC5	ABC transporter
VY92_RS04625	ENOG4105CC5	ABC transporter
VY92_RS04630	ENOG4105DWV	Homoserine O-trans-acetylase
VY92_RS04635	ENOG4107GZ4	SanA protein
VY92_RS04640	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
VY92_RS04645	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VY92_RS04650	ENOG4105D60	lipoprotein releasing system transmembrane protein
VY92_RS04655	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VY92_RS04660	ENOG4105D60	lipoprotein releasing system transmembrane protein
VY92_RS04665	ENOG4105C5I	Dehydrogenase
VY92_RS04670	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
VY92_RS04675	ENOG41063JG	Transcriptional regulator
VY92_RS04680	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VY92_RS04685	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VY92_RS04695	ENOG4105EM2	membrane
VY92_RS04700	ENOG4108Z5K	methylglyoxal synthase
VY92_RS04710	ENOG4108ZAF	Molybdopterin
VY92_RS04715	ENOG4105M00	molybdopterin converting factor, subunit 1
VY92_RS04720	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VY92_RS04725	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VY92_RS04730	ENOG4105CHW	UPF0052 protein
VY92_RS04765	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
VY92_RS04770	ENOG4105EUJ	GTP cyclohydrolase i
VY92_RS04775	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VY92_RS04780	ENOG4105D06	uba thif-type nad fad binding protein
VY92_RS04785	ENOG4105DWU	Membrane
VY92_RS04790	ENOG41090A1	ferritin
VY92_RS04795	ENOG41090A1	ferritin
VY92_RS04805	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VY92_RS04810	ENOG4105Q9Y	Universal stress protein
VY92_RS04820	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
VY92_RS04825	ENOG4107R11	Transcriptional regulator
VY92_RS04830	ENOG4105FE9	pseudouridine synthase
VY92_RS04835	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
VY92_RS04840	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VY92_RS04845	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
VY92_RS04850	ENOG41082RQ	UPF0102 protein
VY92_RS04855	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VY92_RS04860	ENOG4105W4M	Transport-associated protein
VY92_RS04865	ENOG4105C4R	Atp-dependent dna helicase
VY92_RS04880	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
VY92_RS04885	ENOG4105ETT	transcriptional Regulator, LysR family
VY92_RS04890	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VY92_RS04910	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VY92_RS04915	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
VY92_RS04920	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VY92_RS04925	ENOG4105C28	cystathionine
VY92_RS04930	ENOG4105D3R	alkyl hydroperoxide reductase
VY92_RS04940	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VY92_RS04945	ENOG4105D1S	lipid A biosynthesis
VY92_RS04950	ENOG4105C5X	domain protein
VY92_RS04960	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
VY92_RS04965	ENOG4105CN1	protease
VY92_RS04970	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
VY92_RS04975	ENOG4105H2K	paraquat-inducible protein a
VY92_RS04985	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VY92_RS04995	ENOG4105CEI	nitrite reductase
VY92_RS05000	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VY92_RS05005	ENOG4105G0K	glycine radical enzyme YjjI family
VY92_RS05010	ENOG41076CZ	activating enzyme
VY92_RS05015	ENOG4106B0W	Curli production assembly transport component CsgG
VY92_RS05025	ENOG4107Y60	(LipO)protein
VY92_RS05030	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VY92_RS05035	ENOG4105CC0	LysR family Transcriptional regulator
VY92_RS05040	ENOG4105D07	Signal peptide peptidase, SppA
VY92_RS05045	ENOG41069NU	Nitroreductase
VY92_RS05050	ENOG4105EUB	pirin domain protein
VY92_RS05065	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VY92_RS05070	ENOG4108ZP8	Acetolactate synthase small subunit
VY92_RS05075	ENOG4105C7K	acetolactate synthase
VY92_RS05080	ENOG4107S6Z	Na H antiporter
VY92_RS05085	ENOG4108YX2	DNA-binding protein
VY92_RS05095	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
VY92_RS05100	ENOG4107QNR	UPF0135 protein
VY92_RS05105	ENOG4105ETE	Transcriptional regulator (LacI family
VY92_RS05120	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VY92_RS05145	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
VY92_RS05150	ENOG41087AY	ADP-Ribose pyrophosphatase
VY92_RS05155	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
VY92_RS05165	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VY92_RS05170	ENOG4105KUZ	arsenate reductase
VY92_RS05175	ENOG4105DVP	Adenine-specific
VY92_RS05180	ENOG4106NNP	ICEA Protein
VY92_RS05190	ENOG4105D98	threonine synthase
VY92_RS05195	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
VY92_RS05200	ENOG4105CFH	Aspartokinase
VY92_RS05205	ENOG4105DFA	alanine racemase domain protein
VY92_RS05210	ENOG4108UYE	Lactoylglutathione lyase
VY92_RS05215	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
VY92_RS05220	ENOG4105D3Y	Na H antiporter
VY92_RS05225	ENOG4105C26	Dehydrogenase
VY92_RS05230	ENOG4105CK7	Sodium proline symporter
VY92_RS05235	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
VY92_RS05240	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VY92_RS05245	ENOG4105NSG	hemerythrin hhe cation binding domain protein
VY92_RS05250	ENOG4105VIE	preprotein translocase, subunit YajC
VY92_RS05255	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VY92_RS05260	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VY92_RS05265	ENOG4107SC1	transglycosylase
VY92_RS05270	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
VY92_RS05275	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
VY92_RS05280	ENOG4105EMU	Dehydrogenase
VY92_RS05285	ENOG4105D8G	Major Facilitator superfamily
VY92_RS05310	ENOG4105CKT	filamentous hemagglutinin
VY92_RS05335	ENOG4107QMH	DNA methylase
VY92_RS05345	ENOG4105EJC	lysr family transcriptional regulator
VY92_RS05350	ENOG4105DHQ	Histidine kinase
VY92_RS05355	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VY92_RS05360	ENOG4105ETU	transcriptional activator (TenA
VY92_RS05375	ENOG4105EXC	Acyl-transferase
VY92_RS05385	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VY92_RS05390	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VY92_RS05395	ENOG4105PW4	Sugar fermentation stimulation protein homolog
VY92_RS05405	ENOG4106KS4	Sulfatase
VY92_RS05415	ENOG4105D2T	synthase
VY92_RS05430	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VY92_RS05435	ENOG4105D7K	pfkb domain protein
VY92_RS05455	ENOG4105K8N	protein family UPF0079, ATPase
VY92_RS05460	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
VY92_RS05465	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VY92_RS05475	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
VY92_RS05480	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VY92_RS05490	ENOG4105XW2	UPF0263 protein
VY92_RS05505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VY92_RS05515	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
VY92_RS05555	ENOG4105D29	Helix-turn-helix type 11 domain protein
VY92_RS05570	ENOG4105C2I	pirin domain protein
VY92_RS05575	ENOG4105CVE	Lytic murein transglycosylase
VY92_RS05580	ENOG4108RYC	glycosyltransferase
VY92_RS05585	ENOG4108RJ9	Glycosyl transferase, family 2
VY92_RS05595	ENOG41068D6	Glycosyltransferase
VY92_RS05605	ENOG4108ZPC	Polysaccharide pyruvyl transferase
VY92_RS05610	ENOG41080C8	DUF218 domain
VY92_RS05615	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VY92_RS05620	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VY92_RS05625	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VY92_RS05630	ENOG4105D1F	ATP-binding protein
VY92_RS05635	ENOG4107SJW	iron permease, FTR1
VY92_RS05650	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VY92_RS05660	ENOG4105C19	ABC transporter
VY92_RS05665	ENOG4105DSB	aldose 1-epimerase
VY92_RS05675	ENOG4105CRK	lysyL-tRNA synthetase
VY92_RS05690	ENOG4105T95	Thiol disulfide interChange protein
VY92_RS05695	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
VY92_RS05700	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
VY92_RS05705	ENOG4105UYK	outer membrane protein a
VY92_RS05710	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
VY92_RS05715	ENOG4108UUE	Transcriptional regulator
VY92_RS05720	ENOG4105E0A	ABC, transporter
VY92_RS05730	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
VY92_RS05745	ENOG4105E0K	tonB-dependent siderophore receptor
VY92_RS05750	ENOG4105E0K	tonB-dependent siderophore receptor
VY92_RS05760	ENOG4105C44	Serine transporter
VY92_RS05765	ENOG4105WWK	YheO domain protein
VY92_RS05775	ENOG4105CA9	Pyruvate kinase
VY92_RS05780	ENOG4108RCM	Nitroreductase
VY92_RS05785	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
VY92_RS05790	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
VY92_RS05795	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VY92_RS05805	ENOG4105C7S	Dehydrogenase
VY92_RS05810	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
VY92_RS05815	ENOG4105BZN	citrate synthase
VY92_RS05820	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
VY92_RS05825	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
VY92_RS05835	ENOG4107QX8	SPFH domain, Band 7 family protein
VY92_RS05840	ENOG4105K3M	)-transporter
VY92_RS05865	ENOG4105E2R	ROK family
VY92_RS05875	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VY92_RS05880	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
VY92_RS05885	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
VY92_RS05890	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
VY92_RS05900	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VY92_RS05905	ENOG4105C8Y	Acetylornithine aminotransferase
VY92_RS05910	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
VY92_RS05915	ENOG4105C03	ribonuclease
VY92_RS05965	ENOG4105ESV	Glycosyl transferase, family 4
VY92_RS05970	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VY92_RS05975	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
VY92_RS05980	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VY92_RS05985	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VY92_RS05990	ENOG4108ZIG	UPF0231 protein
VY92_RS05995	ENOG4105BZ4	penicillin-binding protein
VY92_RS06005	ENOG4107TSG	Extracellular solute-binding protein, family 5
VY92_RS06010	ENOG4105WD1	Membrane
VY92_RS06015	ENOG4105DGW	oligopeptidase A
VY92_RS06025	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
VY92_RS06030	ENOG4105E33	succinate dehydrogenase
VY92_RS06035	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VY92_RS06040	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VY92_RS06045	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VY92_RS06050	ENOG4105NXV	High-affinity zinc uptake system protein
VY92_RS06055	ENOG4105CUZ	uba thif-type nad fad binding protein
VY92_RS06060	ENOG4105CA3	membrane-bound lytic murein transglycosylase
VY92_RS06075	ENOG4105VEQ	Cold shock protein
VY92_RS06080	ENOG4105DFU	Cell wall formation (By similarity)
VY92_RS06090	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VY92_RS06095	ENOG4105VFK	BolA family
VY92_RS06105	ENOG4105E3I	toluene tolerance
VY92_RS06110	ENOG4107PE3	Mammalian cell entry related domain protein
VY92_RS06115	ENOG4105CY3	ABC transporter, permease
VY92_RS06120	ENOG4105DHJ	ABC, transporter
VY92_RS06130	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
VY92_RS06135	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
VY92_RS06140	ENOG4108IUZ	ABC transporter
VY92_RS06145	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
VY92_RS06160	ENOG4107YCY	Transcriptional regulator
VY92_RS06170	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VY92_RS06175	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
VY92_RS06185	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VY92_RS06190	ENOG4105DMW	Dehydrogenase reductase
VY92_RS06215	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
VY92_RS06220	ENOG41090HJ	UPF0265 protein
VY92_RS06230	ENOG4105C5Y	PTS System
VY92_RS06235	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VY92_RS06240	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
VY92_RS06245	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
VY92_RS06250	ENOG4105E4F	Isochorismate synthase
VY92_RS06255	ENOG4105CHM	Aminotransferase
VY92_RS06265	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VY92_RS06270	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
VY92_RS06275	ENOG4105EE5	Membrane protein terC
VY92_RS06285	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VY92_RS06290	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VY92_RS06300	ENOG4105EN6	Membrane
VY92_RS06305	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
VY92_RS06310	ENOG4105CFH	Aspartokinase
VY92_RS06315	ENOG4107RM6	sulfurtransferase
VY92_RS06320	ENOG4105CUC	YeeE YedE family protein
VY92_RS06325	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VY92_RS06340	ENOG4105D2M	Aldolase
VY92_RS06345	ENOG4105CE4	GlcNAc 6-P deacetylase
VY92_RS06350	ENOG4105E98	transcriptional regulator DeoR family
VY92_RS06360	ENOG4105ENH	Sulfatase
VY92_RS06365	ENOG4105C4X	radical SAM domain protein
VY92_RS06380	ENOG4105DAS	pts system
VY92_RS06385	ENOG4105F3R	pts system mannose fructose sorbose family iid
VY92_RS06390	ENOG4105ETZ	PTS System
VY92_RS06395	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
VY92_RS06400	ENOG4105E70	isomerase
VY92_RS06405	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
VY92_RS06410	ENOG4105CBG	Sulfatase
VY92_RS06420	ENOG4105CHR	reductase
VY92_RS06430	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
VY92_RS06435	ENOG4108UHU	Aldolase
VY92_RS06440	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
VY92_RS06445	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VY92_RS06455	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
VY92_RS06475	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VY92_RS06480	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
VY92_RS06485	ENOG4108UBT	opacity-associated protein
VY92_RS06490	ENOG4105DH7	May be involved in recombination (By similarity)
VY92_RS06495	ENOG4105II7	pyrroline-5-carboxylate reductase
VY92_RS06500	ENOG4105D8G	Major Facilitator superfamily
VY92_RS06505	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VY92_RS06510	ENOG4105CQC	Prephenate dehydratase
VY92_RS06530	ENOG4105EMU	Dehydrogenase
VY92_RS06545	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VY92_RS06550	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VY92_RS06555	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VY92_RS06560	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
VY92_RS06565	ENOG4105CPF	Cell wall formation (By similarity)
VY92_RS06570	ENOG4105DFU	Cell wall formation (By similarity)
VY92_RS06575	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VY92_RS06580	ENOG4105CNI	cell division protein FtsW
VY92_RS06585	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VY92_RS06590	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
VY92_RS06595	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
VY92_RS06600	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VY92_RS06605	ENOG4105CJN	penicillin-binding protein
VY92_RS06615	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VY92_RS06620	ENOG4108V6E	Cell division protein mraZ
VY92_RS06640	ENOG4105C9A	Phoh family
VY92_RS06650	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
VY92_RS06655	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
VY92_RS06660	ENOG4105E7A	Glutamine amidotransferase
VY92_RS06665	ENOG4105C44	Serine transporter
VY92_RS06670	ENOG4105EJQ	L-serine dehydratase
VY92_RS06675	ENOG4105DA4	cytochrome c-type biogenesis protein
VY92_RS06680	ENOG4107QX9	Thiol disulfide interChange protein
VY92_RS06685	ENOG4108DMF	Cytochrome C biogenesis protein
VY92_RS06690	ENOG4108DMF	Cytochrome C biogenesis protein
VY92_RS06695	ENOG4105CBX	hi0933 family
VY92_RS06700	ENOG4105C0B	DNA polymerase III (alpha subunit)
VY92_RS06705	ENOG4105DVI	reductase, NrfD
VY92_RS06710	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VY92_RS06715	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
VY92_RS06720	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
VY92_RS06725	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
VY92_RS06740	ENOG4105DZ1	carboxypeptidase
VY92_RS06745	ENOG4105K6T	rare lipoprotein A
VY92_RS06750	ENOG4105CNI	cell division protein FtsW
VY92_RS06755	ENOG4105CJN	penicillin-binding protein
VY92_RS06765	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
VY92_RS06770	ENOG4105C1J	atp-dependent rna helicase
VY92_RS06775	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
VY92_RS06780	ENOG4105F27	Major Facilitator
VY92_RS06790	ENOG4105DHP	deoxycytidine triphosphate deaminase
VY92_RS06800	ENOG4107RCV	ABC transporter, permease
VY92_RS06805	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VY92_RS06830	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
VY92_RS06835	ENOG4105CB5	ATP-dependent DNA helicase recG
VY92_RS06840	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VY92_RS06845	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
VY92_RS06850	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VY92_RS06855	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VY92_RS06865	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VY92_RS06870	ENOG4105DJ4	phosphatidylserine decarboxylase
VY92_RS06885	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VY92_RS06890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VY92_RS06895	ENOG4105HSA	Protein of unknown function (DUF452)
VY92_RS06900	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
VY92_RS06905	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
VY92_RS06910	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
VY92_RS06920	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
VY92_RS06925	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VY92_RS06930	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
VY92_RS06935	ENOG4105CHR	reductase
VY92_RS06950	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VY92_RS06955	ENOG4105EQ2	LysR family Transcriptional regulator
VY92_RS06995	ENOG4105ENX	hydrolase
VY92_RS07025	ENOG4108UUM	single-stranded DNA-binding protein
VY92_RS07030	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VY92_RS07035	ENOG4105DFF	Rod shape-determining protein mreb
VY92_RS07040	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
VY92_RS07050	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
VY92_RS07055	ENOG41090JE	Utilization Protein
VY92_RS07060	ENOG4107ENK	receptor
VY92_RS07080	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VY92_RS07090	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
VY92_RS07095	ENOG4105EVU	fructokinase
VY92_RS07100	ENOG4108R66	Conserved Protein
VY92_RS07105	ENOG4105QEK	Transcriptional regulator
VY92_RS07115	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VY92_RS07135	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
VY92_RS07145	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VY92_RS07150	ENOG4105YP7	UPF0270 protein
VY92_RS07155	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
VY92_RS07160	ENOG4105CNN	ABC, transporter
VY92_RS07165	ENOG4105C2J	ABC transporter
VY92_RS07170	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VY92_RS07175	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VY92_RS07180	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VY92_RS07185	ENOG4105D0A	hydroxylase
VY92_RS07190	ENOG4107RAQ	aminopeptidase
VY92_RS07195	ENOG4105E07	UPF0149 protein
VY92_RS07200	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
VY92_RS07210	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
VY92_RS07215	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VY92_RS07220	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
VY92_RS07225	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VY92_RS07230	ENOG4108R96	Methyltransferase, YaeB family
VY92_RS07240	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VY92_RS07245	ENOG4105C8P	)-transporter
VY92_RS07250	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VY92_RS07255	ENOG4105JC1	sterol-binding domain protein
VY92_RS07260	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VY92_RS07265	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VY92_RS07270	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
VY92_RS07275	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VY92_RS07280	ENOG4105D52	delta-aminolevulinic acid dehydratase
VY92_RS07285	ENOG4105EYA	deoxyribonuclease
VY92_RS07290	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
VY92_RS07300	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VY92_RS07305	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
VY92_RS07315	ENOG4105C6T	cysteine synthase
VY92_RS07375	ENOG4105K4U	addiction module toxin, RelE StbE family
VY92_RS07415	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VY92_RS07430	ENOG4108JA2	transcriptioN-repair coupling factor
VY92_RS07435	ENOG4105M6F	mutator MutT protein
VY92_RS07455	ENOG4105DFE	Dna adenine methylase
VY92_RS07460	ENOG4105D49	3-dehydroquinate synthase
VY92_RS07465	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VY92_RS07470	ENOG4105E4G	Type IV pilus
VY92_RS07495	ENOG4108JQC	penicillin-binding protein 1A
VY92_RS07525	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
VY92_RS07530	ENOG4105DFS	Conserved Protein
VY92_RS07540	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
VY92_RS07545	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
VY92_RS07565	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VY92_RS07575	ENOG4108KU3	Integrase
VY92_RS07585	ENOG4105WXW	Antirepressor
VY92_RS07610	ENOG4108UUM	single-stranded DNA-binding protein
VY92_RS07715	ENOG4107EPN	Domain of unknown function (DUF1508)
VY92_RS07740	ENOG4105RWQ	Protein of unknown function (DUF1364)
VY92_RS07780	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VY92_RS07795	ENOG4107EPN	Domain of unknown function (DUF1508)
VY92_RS07840	ENOG4108UUM	single-stranded DNA-binding protein
VY92_RS07855	ENOG4105DH7	May be involved in recombination (By similarity)
VY92_RS07905	ENOG4108KU3	Integrase
VY92_RS07925	ENOG4105C28	cystathionine
VY92_RS07930	ENOG4105C5I	Dehydrogenase
VY92_RS07935	ENOG4105K63	Thioredoxin
VY92_RS07940	ENOG4105WPN	DNA integration recombination invertion protein
VY92_RS07945	ENOG4105EAH	synthase
VY92_RS07950	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VY92_RS07955	ENOG4105K46	50S ribosomal protein l27
VY92_RS07960	ENOG4105QYV	Membrane
VY92_RS07965	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VY92_RS08065	ENOG4105CKT	filamentous hemagglutinin
VY92_RS08065	ENOG4105CKT	filamentous hemagglutinin
VY92_RS08070	ENOG4105D5K	Hemolysin activator protein
VY92_RS08075	ENOG4105HMI	Membrane
VY92_RS08080	ENOG4105NTK	Transcriptional repressor Mpra
VY92_RS08095	ENOG4105NTK	Transcriptional repressor Mpra
VY92_RS08100	ENOG4105CW7	secretion protein, HlyD family
VY92_RS08105	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VY92_RS08110	ENOG4105C2N	RNA methyltransferase TrmH family group 3
VY92_RS08115	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VY92_RS08120	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VY92_RS08135	ENOG4105C3F	Signal peptidase i
VY92_RS08140	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VY92_RS08145	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
VY92_RS08170	ENOG4105CTQ	phosphohexokinase
VY92_RS08175	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VY92_RS08180	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VY92_RS08195	ENOG4105BZU	Histidine kinase
VY92_RS08200	ENOG4105C09	Bile acid
VY92_RS08205	ENOG4105EYM	Major Facilitator superfamily
VY92_RS08210	ENOG4105CMR	udp-glucose 4-epimerase
VY92_RS08220	ENOG4105C7N	Xanthine uracil vitamin C permease
VY92_RS08225	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
VY92_RS08230	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VY92_RS08235	ENOG4105CSA	Coproporphyrinogen iii oxidase
VY92_RS08245	ENOG4105W39	Membrane
VY92_RS08250	ENOG4108UW5	maltose o-acetyltransferase
VY92_RS08255	ENOG4107VXZ	Hydrolase
VY92_RS08265	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
VY92_RS08270	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
VY92_RS08275	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
VY92_RS08280	ENOG4108UM1	dedA family
VY92_RS08290	ENOG4108K5P	(LipO)protein
VY92_RS08300	ENOG4105ERG	peptidase m48, ste24p
VY92_RS08305	ENOG4105F0N	pyrophosphate phospho-hydrolase
VY92_RS08310	ENOG4105CIC	tryptophan-specific transport protein
VY92_RS08315	ENOG4105DMQ	Methyltransferase
VY92_RS08320	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
VY92_RS08325	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
VY92_RS08335	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VY92_RS08340	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
VY92_RS08345	ENOG4105DFS	Conserved Protein
VY92_RS08350	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
VY92_RS08355	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VY92_RS08360	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
VY92_RS08365	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
VY92_RS08375	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
VY92_RS08380	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
VY92_RS08385	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VY92_RS08390	ENOG4105C2W	permease
VY92_RS08395	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
VY92_RS08400	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VY92_RS08405	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VY92_RS08410	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VY92_RS08415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VY92_RS08420	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
VY92_RS08425	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
VY92_RS08430	ENOG41060IM	Heme exporter protein
VY92_RS08435	ENOG4105X3C	heme exporter protein
VY92_RS08440	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
VY92_RS08445	ENOG4105DA4	cytochrome c-type biogenesis protein
VY92_RS08450	ENOG4107QX9	Thiol disulfide interChange protein
VY92_RS08455	ENOG4108M1T	Cytochrome c-type biogenesis protein
VY92_RS08460	ENOG4108M1T	Cytochrome c-type biogenesis protein
VY92_RS08465	ENOG4108HWV	)-transporter
VY92_RS08470	ENOG4105C2J	ABC transporter
VY92_RS08475	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
VY92_RS08480	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VY92_RS08485	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VY92_RS08490	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
VY92_RS08500	ENOG4105F1A	Pyruvate formate-lyase
VY92_RS08505	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
VY92_RS08510	ENOG4105C6N	Formate acetyltransferase
VY92_RS08515	ENOG4105TMB	Formate nitrite transporter
VY92_RS08520	ENOG4105K59	histidine triad (HIT) protein
VY92_RS08530	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
VY92_RS08535	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
VY92_RS08540	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
VY92_RS08550	ENOG41063M6	Cell Division Protein
VY92_RS08555	ENOG4105C25	Primosomal protein n'
VY92_RS08560	ENOG4105VFB	Binds the 23S rRNA (By similarity)
VY92_RS08565	ENOG4105C37	(CBS) domain
VY92_RS08570	ENOG4105RX8	Protein of unknown function (DUF1523)
VY92_RS08575	ENOG4105F8V	Hydrolase, tatD family
VY92_RS08580	ENOG4107QRG	dna polymerase iii
VY92_RS08585	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VY92_RS08590	ENOG4105HHA	aminodeoxychorismate lyase
VY92_RS08600	ENOG4108JQ1	Dehydrogenase
VY92_RS08605	ENOG4105E66	phosphoriboisomerase A
VY92_RS08615	ENOG4105EPW	hflc protein
VY92_RS08620	ENOG4107QJR	hflk protein
VY92_RS08625	ENOG4105W8Z	4'-phosphopantetheinyl transferase
VY92_RS08635	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
VY92_RS08640	ENOG41065S8	Opacity family porin protein
VY92_RS08645	ENOG4105GPY	SprT protein
VY92_RS08650	ENOG4105D9N	nucleoside
VY92_RS08655	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
VY92_RS08660	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VY92_RS08670	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VY92_RS08695	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
VY92_RS08715	ENOG4105C4R	Atp-dependent dna helicase
VY92_RS08725	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VY92_RS08735	ENOG4105VCP	PTS System
VY92_RS08740	ENOG4105VZJ	PTS System
VY92_RS08745	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VY92_RS08755	ENOG4105CK1	PTS System
VY92_RS08760	ENOG4106N3A	copper homeostasis protein cutc
VY92_RS08765	ENOG4105BZS	acriflavin resistance protein
VY92_RS08770	ENOG410624X	efflux transporter, rnd family, mfp subunit
VY92_RS08780	ENOG4108RRZ	Transcription elongation factor GreB
VY92_RS08795	ENOG4105BZM	domain protein
VY92_RS08800	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VY92_RS08805	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VY92_RS08810	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
VY92_RS08820	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
VY92_RS08825	ENOG4108WPU	DNA polymerase III subunit psi
VY92_RS08830	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
VY92_RS08835	ENOG4108IQE	Amp-dependent synthetase and ligase
VY92_RS08840	ENOG4108IJ0	Aspartate ammonia-lyase
VY92_RS08845	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
VY92_RS08850	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VY92_RS08875	ENOG4105C94	Transporter
VY92_RS08880	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
VY92_RS08885	ENOG4105C2M	dna polymerase I
VY92_RS08890	ENOG4108ST3	glycosyltransferase
VY92_RS08895	ENOG4105E61	Mannitol repressor protein
VY92_RS08900	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
VY92_RS08905	ENOG4105CTS	PTS system mannitol-specific
VY92_RS08910	ENOG41067XB	TonB family
VY92_RS08915	ENOG4105M15	transport protein ExbD
VY92_RS08920	ENOG4105M8K	biopolymer transport protein
VY92_RS08925	ENOG4108JU6	CBS domain protein
VY92_RS08930	ENOG4106KVJ	cytochrome C assembly protein
VY92_RS08935	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VY92_RS08950	ENOG4105K89	arsenate reductase
VY92_RS08960	ENOG4105E5Z	arginine transporter ATP-binding subunit
VY92_RS08965	ENOG4106PMH	Extracellular solute-binding protein family 3
VY92_RS08970	ENOG4105GBT	ABC transporter
VY92_RS08975	ENOG4105DMR	ABC, transporter
VY92_RS08980	ENOG4108JU5	Magnesium and cobalt efflux protein
VY92_RS08985	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
VY92_RS08990	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
VY92_RS09000	ENOG4105C5F	glutamine synthetase
VY92_RS09005	ENOG4105CI3	gtp-binding protein typa
VY92_RS09020	ENOG41068D6	Glycosyltransferase
VY92_RS09035	ENOG4105C30	Nad-dependent epimerase dehydratase
VY92_RS09055	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VY92_RS09060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
VY92_RS09070	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VY92_RS09075	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VY92_RS09085	ENOG4105KJB	cyd operon protein YbgE
VY92_RS09095	ENOG4107YD3	Thioesterase
VY92_RS09100	ENOG4105E02	MotA TolQ exbB proton channel
VY92_RS09120	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VY92_RS09155	ENOG4105DSY	exodeoxyribonuclease V, gamma
VY92_RS09160	ENOG4108K4B	hydrolase
VY92_RS09165	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
VY92_RS09170	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
VY92_RS09205	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
VY92_RS09210	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VY92_RS09215	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
VY92_RS09265	ENOG4108RR8	protoporphyrinogen oxidase
VY92_RS09270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VY92_RS09280	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
VY92_RS09285	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
VY92_RS09290	ENOG41063SB	peptidase
VY92_RS09295	ENOG4105PXI	polysaccharide deacetylase
VY92_RS09300	ENOG4105MJ2	Competence protein
VY92_RS09310	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VY92_RS09320	ENOG4105D4A	Cell wall formation (By similarity)
VY92_RS09325	ENOG4105BZU	Histidine kinase
VY92_RS09340	ENOG4108BGM	Quinol dehydrogenase periplasmic component
VY92_RS09345	ENOG4105GXZ	Ferredoxin-type protein NapH
VY92_RS09350	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
VY92_RS09355	ENOG4105CUW	cytochrome C-TYPE protein
VY92_RS09365	ENOG4105RT1	May be involved in cell division (By similarity)
VY92_RS09375	ENOG4108YZY	peptidylprolyl cis-trans isomerase
VY92_RS09385	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
VY92_RS09390	ENOG4105C1A	potassium transporter peripheral membrane
VY92_RS09405	ENOG4107R3N	Filamentation induced by cAMP protein fic
VY92_RS09410	ENOG4105CEP	NADH dehydrogenase
VY92_RS09415	ENOG4105D7K	pfkb domain protein
VY92_RS09425	ENOG4105D2N	Aldolase
VY92_RS09430	ENOG4105BZA	Phosphoglycerate kinase
VY92_RS09435	ENOG41083KI	ribonuclease, T2
VY92_RS09440	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VY92_RS09445	ENOG4105EIB	trna rrna methyltransferase
VY92_RS09450	ENOG4105JIM	Phosphatidylserine synthase
VY92_RS09460	ENOG4108RCM	Nitroreductase
VY92_RS09465	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VY92_RS09470	ENOG4107YZP	Rhodanese domain protein
VY92_RS09480	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VY92_RS09485	ENOG4105D7W	serine acetyltransferase
VY92_RS09490	ENOG4105F9E	Shikimate 5-dehydrogenase
VY92_RS09495	ENOG4105DIJ	Phosphoethanolamine transferase
VY92_RS09500	ENOG4108Z6Z	Transcriptional regulator
VY92_RS09515	ENOG4105C6K	Malic enzyme
VY92_RS09520	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VY92_RS09525	ENOG4105E0M	Sulfatase
VY92_RS09530	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VY92_RS09540	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
VY92_RS09545	ENOG4105K5M	30s ribosomal protein S16
VY92_RS09550	ENOG4105M5K	heptosyltransferase
VY92_RS09555	ENOG4106WTF	Glycosyl transferase, family 2
VY92_RS09560	ENOG410667J	hydrolase
VY92_RS09565	ENOG4105DAS	pts system
VY92_RS09570	ENOG4105ETZ	PTS System
VY92_RS09575	ENOG4105F3R	pts system mannose fructose sorbose family iid
VY92_RS09585	ENOG4105D9M	gamma-glutamylcysteine synthetase
VY92_RS09590	ENOG4108ZIT	Ferredoxin, 2FE-2S
VY92_RS09595	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VY92_RS09600	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VY92_RS09605	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VY92_RS09610	ENOG4108Z4V	iron-sulfur cluster assembly
VY92_RS09615	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VY92_RS09620	ENOG4105C3J	Cysteine desulfurase
VY92_RS09625	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
VY92_RS09630	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
VY92_RS09635	ENOG4105ECY	inositol monophosphatase
VY92_RS09645	ENOG4105EZR	dyp-type peroxidase family protein
VY92_RS09650	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
VY92_RS09655	ENOG4105C1J	atp-dependent rna helicase
VY92_RS09660	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VY92_RS09670	ENOG410903C	(LipO)protein
VY92_RS09675	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
VY92_RS09680	ENOG4105JAB	phenazine biosynthesis protein, phzf family
VY92_RS09685	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VY92_RS09690	ENOG4108YZA	Nitrogen regulatory protein pii
VY92_RS09695	ENOG4105BZU	Histidine kinase
VY92_RS09695	ENOG4105BZU	Histidine kinase
VY92_RS09705	ENOG4108MJ5	VirK protein
VY92_RS09710	ENOG4105D7A	ATP-binding protein
VY92_RS09715	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VY92_RS09720	ENOG4105C34	Pseudouridine synthase
VY92_RS09725	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
VY92_RS09730	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
VY92_RS09745	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VY92_RS09755	ENOG4105C9X	ppx gppa phosphatase
VY92_RS09760	ENOG4105MA0	exported protein
VY92_RS09770	ENOG4105CJR	Integral membrane protein (MviN
VY92_RS09775	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
VY92_RS09780	ENOG41062Z9	Membrane
VY92_RS09785	ENOG4105EAC	phosphoserine phosphatase
VY92_RS09790	ENOG4108VPT	UPF0234 protein
VY92_RS09795	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
VY92_RS09800	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
VY92_RS09805	ENOG4108WFC	UPF0438 protein yifE
VY92_RS09810	ENOG4108Z33	Thiol disulfide Interchange Protein
VY92_RS09820	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VY92_RS09825	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
VY92_RS09830	ENOG4105DSJ	YicC domain protein
VY92_RS09835	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VY92_RS09840	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VY92_RS09845	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
VY92_RS09850	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
VY92_RS09860	ENOG4105E68	Sulfatase
VY92_RS09875	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VY92_RS09880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VY92_RS09885	ENOG4106HK8	GPR1 FUN34 yaaH family protein
VY92_RS09890	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VY92_RS09895	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VY92_RS09900	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VY92_RS09905	ENOG4108VZM	50s ribosomal protein L10
VY92_RS09910	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VY92_RS09915	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VY92_RS09935	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
VY92_RS09940	ENOG4105PM1	preprotein translocase subunit SecE
VY92_RS09945	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VY92_RS09950	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VY92_RS09960	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
VY92_RS09975	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
VY92_RS09980	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
VY92_RS09990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VY92_RS10000	ENOG4105EHV	domain protein
VY92_RS10005	ENOG4105C5Q	Transcriptional regulator
VY92_RS10010	ENOG4105EJ2	Transcriptional regulator
VY92_RS10015	ENOG4108EUD	Lysophospholipase
VY92_RS10020	ENOG4107Z6W	Protein CrcB homolog
VY92_RS10035	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
VY92_RS10040	ENOG4105C01	Dihydroxy-acid dehydratase
VY92_RS10050	ENOG4105C7B	Threonine dehydratase
VY92_RS10085	ENOG4108TMH	cytolethal distending toxin
VY92_RS10090	ENOG4106BMH	cytolethal distending toxin
VY92_RS10095	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
VY92_RS10100	ENOG4108R3E	Dna-3-methyladenine glycosylase i
VY92_RS10105	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VY92_RS10110	ENOG4105R3P	Inner membrane protein yagU
VY92_RS10120	ENOG4108R99	pseudouridine synthase
VY92_RS10125	ENOG4108HMX	isocitrate dehydrogenase (NADP)
VY92_RS10130	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
VY92_RS10135	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VY92_RS10145	ENOG4108IA2	Sodium pantothenate symporter
VY92_RS10150	ENOG4105RG0	Membrane
VY92_RS10160	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VY92_RS10185	ENOG4108IPT	Naphthoate synthase
VY92_RS10210	ENOG4105EI2	Pseudouridine synthase
VY92_RS10215	ENOG4105EM7	Selenocysteine-specific translation elongation factor
VY92_RS10225	ENOG41090ED	Protein with unknown function (DUF469)
VY92_RS10230	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
VY92_RS10235	ENOG4105C0P	Mg chelatase subunit ChlI
VY92_RS10240	ENOG4105DY8	decarboxylase
VY92_RS10245	ENOG4108JPW	Aminotransferase
VY92_RS10250	ENOG4108ZPB	UPF0306 protein
VY92_RS10255	ENOG410601J	HemY protein
VY92_RS10260	ENOG4105ECF	c-methyltransferase
VY92_RS10270	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VY92_RS10275	ENOG4107T0K	Adenylate cyclase
VY92_RS10280	ENOG4105WH1	Two component transcriptional regulator luxr family
VY92_RS10290	ENOG4107S2Z	UPF0761 membrane protein
VY92_RS10295	ENOG4105K5B	UPF0225 protein
VY92_RS10300	ENOG41069M3	Transcriptional regulator
VY92_RS10305	ENOG4105DG4	malate L-lactate dehydrogenase
VY92_RS10310	ENOG4108R66	Conserved Protein
VY92_RS10315	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
VY92_RS10320	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VY92_RS10325	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VY92_RS10330	ENOG4105CMG	Carbohydrate kinase
VY92_RS10335	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
VY92_RS10340	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
VY92_RS10345	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VY92_RS10350	ENOG4105CAK	Cell division ATP-binding protein ftsE
VY92_RS10355	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
VY92_RS10360	ENOG4105VZ9	UPF0235 protein
VY92_RS10365	ENOG4108VIA	integral membrane protein
VY92_RS10370	ENOG4107QUT	magnesium and cobalt transport protein CorA
VY92_RS10425	ENOG4105UKP	Protein of unknown function (DUF1778)
VY92_RS10640	ENOG4108IYH	Dna topoisomerase
VY92_RS10680	ENOG4108ZHR	arsR family transcriptional regulator
VY92_RS10695	ENOG4105D6U	Sodium Glutamate Symporter
VY92_RS10710	ENOG4105F2I	Transposase
VY92_RS10725	ENOG4105F2I	Transposase
VY92_RS10735	ENOG4108UUM	single-stranded DNA-binding protein
VY92_RS10770	ENOG4105CDU	Replicative dna helicase
VY92_RS10790	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
VY92_RS10795	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
VY92_RS10800	ENOG4105CEN	a g-specific adenine glycosylase
VY92_RS10805	ENOG4105DFW	ABC transporter
VY92_RS10810	ENOG4105C2J	ABC transporter
VY92_RS10815	ENOG4108HWW	ABC transporter
VY92_RS10825	ENOG4108UJU	UPF0301 protein
VY92_RS10830	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
VY92_RS10840	ENOG410787A	Pts system, glucitol sorbitol-specific
VY92_RS10845	ENOG4105DZY	Pts system, glucitol sorbitol-specific
VY92_RS10850	ENOG4105VI0	Pts system, glucitol sorbitol-specific
VY92_RS10855	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
VY92_RS10860	ENOG4105J92	DNA-binding transcriptional activator GutM
VY92_RS10865	ENOG410804X	Transcriptional regulator
VY92_RS10875	ENOG41075W9	High frequency lysogenization protein HflD homolog
VY92_RS10880	ENOG4107QTF	adenylosuccinate lyase
VY92_RS10885	ENOG4105DFD	Na H antiporter
VY92_RS10890	ENOG4105CHM	Aminotransferase
VY92_RS10895	ENOG4105C93	Xylose Isomerase
VY92_RS10900	ENOG4105CMG	Carbohydrate kinase
VY92_RS10905	ENOG4105T16	Transcriptional regulator (AraC family)
VY92_RS10915	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VY92_RS10950	ENOG4108TEB	UPF0114 protein
VY92_RS10955	ENOG4105CGY	Dna recombination protein
VY92_RS10960	ENOG4108Z03	MAF-like protein
VY92_RS10965	ENOG4108WI1	Dna topoisomerase
VY92_RS10970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VY92_RS10975	ENOG4105E2X	shikimate dehydrogenase
VY92_RS10980	ENOG4105C8J	)-transporter
VY92_RS10990	ENOG4105CA0	peroxidase
VY92_RS10995	ENOG4105BZ1	(ABC) transporter
VY92_RS11000	ENOG4108JJ9	ABC, transporter
VY92_RS11010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VY92_RS11015	ENOG4105CBT	Fructose-1,6-bisphosphatase
VY92_RS11025	ENOG4105QTB	Flavodoxin
VY92_RS11030	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
VY92_RS11035	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
VY92_RS11060	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VY92_RS11065	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
VY92_RS11070	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
VY92_RS11075	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
VY92_RS11080	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
VY92_RS11085	ENOG4105ECY	inositol monophosphatase
VY92_RS11090	ENOG4105CXY	transporter
VY92_RS11125	ENOG4105PGM	cation diffusion facilitator family transporter
VY92_RS11140	ENOG4108YYD	acetyltransferase
VY92_RS11150	ENOG4107QMH	DNA methylase
VY92_RS11160	ENOG4105CIN	aminoacyl-histidine dipeptidase
VY92_RS11185	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VY92_RS11195	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VY92_RS11210	ENOG4105D9Q	decarboxylase (Beta subunit)
VY92_RS11215	ENOG4107QSA	Oxaloacetate decarboxylase
VY92_RS11220	ENOG4106AFN	Lyase and sodium transporter (By similarity)
VY92_RS11225	ENOG4105C5H	ABC transporter
VY92_RS11230	ENOG4105CK7	Sodium proline symporter
VY92_RS11240	ENOG4105CBG	Sulfatase
VY92_RS11245	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VY92_RS11250	ENOG4105EMY	transcriptional regulator
VY92_RS11255	ENOG4105DTR	rard protein
VY92_RS11260	ENOG4105DXN	mazG family
VY92_RS11265	ENOG4108M6U	Universal stress protein A
VY92_RS11275	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
VY92_RS11285	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VY92_RS11290	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VY92_RS11295	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
VY92_RS11300	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VY92_RS11305	ENOG4105D01	(LipO)protein
VY92_RS11310	ENOG4108UMI	ABC transporter, permease
VY92_RS11315	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
VY92_RS11320	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VY92_RS11350	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VY92_RS11355	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VY92_RS11365	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VY92_RS11370	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VY92_RS11375	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
VY92_RS11380	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VY92_RS11395	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
VY92_RS11400	ENOG41067V7	50S ribosomal protein L36
VY92_RS11405	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VY92_RS11410	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VY92_RS11415	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VY92_RS11420	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VY92_RS11425	ENOG4108ZT0	50S ribosomal protein l17
VY92_RS11435	ENOG4105W0Z	cytoplasmic protein
VY92_RS11440	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
VY92_RS11445	ENOG4108VVQ	metallophosphoesterase
VY92_RS11455	ENOG4105DFP	Integrase
VY92_RS11530	ENOG4105DZR	Type I site-specific deoxyribonuclease
VY92_RS11545	ENOG4105EKX	Restriction modification system DNA (Specificity
VY92_RS11550	ENOG4105CVR	type I restriction-modification system
VY92_RS11555	ENOG4105IEY	(LipO)protein
VY92_RS11570	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VY92_RS11575	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VY92_RS11580	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VY92_RS11585	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VY92_RS11590	ENOG4108EGU	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
VY92_RS11595	ENOG4105CJ2	(LipO)protein
VY92_RS11605	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VY92_RS11610	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
VY92_RS11620	ENOG4105D6U	Sodium Glutamate Symporter
VY92_RS11650	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VY92_RS11655	ENOG4105E09	nadh pyrophosphatase
VY92_RS11660	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
VY92_RS11665	ENOG4105R2J	Conserved Protein
VY92_RS11670	ENOG4105K70	DNA-binding protein
VY92_RS11675	ENOG410804X	Transcriptional regulator
VY92_RS11680	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VY92_RS11690	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
VY92_RS11695	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VY92_RS11700	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
VY92_RS11705	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
VY92_RS11710	ENOG4105VQK	sigma E regulatory protein, MucB RseB
VY92_RS11715	ENOG41069PW	sigma-e factor negative regulatory protein
VY92_RS11720	ENOG4105EMN	RNA polymerase sigma factor
VY92_RS11725	ENOG4105Y75	tpr repeat protein
VY92_RS11735	ENOG4105DVA	methyltransferase
VY92_RS11760	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
VY92_RS11765	ENOG4105KJF	protein tyrosine phosphatase
VY92_RS11770	ENOG4105BZ8	glutamate synthase
VY92_RS11775	ENOG4105CBC	glutamate synthase
VY92_RS11785	ENOG4105DKP	glycosyl transferase, family 9
VY92_RS11790	ENOG4105BZ1	(ABC) transporter
VY92_RS11795	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
VY92_RS11800	ENOG4105C5B	carbamate kinase
VY92_RS11810	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
VY92_RS11820	ENOG4107REC	cytoplasmic protein
VY92_RS11825	ENOG4107R1Q	Membrane protein FdrA
VY92_RS11835	ENOG4108NUU	Transcriptional regulator
VY92_RS11845	ENOG4107REC	cytoplasmic protein
VY92_RS11850	ENOG4107R1Q	Membrane protein FdrA
VY92_RS11855	ENOG4107SNB	ankyrin repeat protein YahD
VY92_RS11875	ENOG4108RS6	transposase
VY92_RS11880	ENOG4105D7V	transposase
VY92_RS11885	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VY92_RS11890	ENOG4105CDA	abc transporter atp-binding protein
VY92_RS11895	ENOG4105E5Q	amino acid AbC transporter
VY92_RS11900	ENOG4105EAB	amino acid AbC transporter
VY92_RS11905	ENOG4105D4P	Coproporphyrinogen iii oxidase
VY92_RS11910	ENOG4105XCT	Protein of unknown function (DUF2489)
VY92_RS11915	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
VY92_RS11920	ENOG4105D3G	Pseudouridine synthase
VY92_RS11925	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
VY92_RS11935	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
VY92_RS11945	ENOG4105C26	Dehydrogenase
VY92_RS11950	ENOG4105DH8	myo-inositol catabolism
VY92_RS11965	ENOG4108HYK	gCN5-related N-acetyltransferase
VY92_RS12000	ENOG4105EDR	glucose galactose transporter
VY92_RS12005	ENOG4107W7X	Aldolase
VY92_RS12015	ENOG4105CMG	Carbohydrate kinase
VY92_RS12020	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
VY92_RS12025	ENOG4107EDW	L-fucose operon activator
VY92_RS12030	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
VY92_RS12035	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
VY92_RS12050	ENOG4105XA0	heptosyltransferase ii
VY92_RS12055	ENOG4105D16	lipopolysaccharide heptosyltransferase i
VY92_RS12060	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VY92_RS12065	ENOG4107104	thymidine kinase
VY92_RS12085	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
VY92_RS12090	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VY92_RS12105	ENOG4105KZW	UPF0381 protein
VY92_RS12110	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
VY92_RS12115	ENOG41060A7	DNA polymerase beta domain protein region
VY92_RS12120	ENOG41062MS	nucleotidyltransferase substrate binding protein
VY92_RS12125	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
VY92_RS12130	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
VY92_RS12135	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
VY92_RS12140	ENOG4105EPD	Oligopeptide transporter, Opt family
VY92_RS12145	ENOG4105VEJ	Heat shock protein
VY92_RS12150	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
VY92_RS12155	ENOG4105ETE	Transcriptional regulator (LacI family
VY92_RS12170	ENOG4105CMG	Carbohydrate kinase
VY92_RS12175	ENOG4105C2J	ABC transporter
VY92_RS12180	ENOG4105CNN	ABC, transporter
VY92_RS12185	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VY92_RS12195	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
VY92_RS12210	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VY92_RS12215	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
VY92_RS12220	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VY92_RS12225	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VY92_RS12235	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VY92_RS12240	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VY92_RS12245	ENOG41083MP	50s ribosomal protein l29
VY92_RS12250	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VY92_RS12260	ENOG4105DFP	Integrase
VY92_RS12345	ENOG41061CV	Terminase small subunit 
VY92_RS12410	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins