locus-tag	class	description
CEW87_RS00030	COG0247	lactate metabolic process
CEW87_RS00055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS00115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS00120	COG0625	glutathione transferase activity
CEW87_RS00125	COG0069	glutamate synthase activity
CEW87_RS00130	COG1454	alcohol dehydrogenase
CEW87_RS00150	COG4772	TonB-dependent receptor
CEW87_RS00165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS00175	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS00180	COG0693	protein deglycase activity
CEW87_RS00200	COG1024	Enoyl-CoA hydratase
CEW87_RS00210	COG2814	Major facilitator Superfamily
CEW87_RS00245	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS00250	COG0183	Belongs to the thiolase family
CEW87_RS00260	COG1024	Enoyl-CoA hydratase
CEW87_RS00265	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS00270	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS00275	COG0837	glucose binding
CEW87_RS00280	COG0166	Belongs to the GPI family
CEW87_RS00295	COG0142	geranyltranstransferase activity
CEW87_RS00300	COG0584	glycerophosphoryl diester phosphodiesterase
CEW87_RS00315	COG0667	Aldo Keto reductase
CEW87_RS00320	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CEW87_RS00325	COG0513	Belongs to the DEAD box helicase family
CEW87_RS00335	COG1428	Deoxynucleoside kinase
CEW87_RS00340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEW87_RS00345	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEW87_RS00350	COG0517	IMP dehydrogenase activity
CEW87_RS00350	COG0516	GMP reductase activity
CEW87_RS00355	COG0308	aminopeptidase N
CEW87_RS00385	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW87_RS00395	COG0589	response to stress
CEW87_RS00400	COG0538	isocitrate dehydrogenase activity
CEW87_RS00405	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CEW87_RS00415	COG2010	Cytochrome c
CEW87_RS00435	COG4654	Cytochrome c, class I
CEW87_RS00440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEW87_RS00445	COG0640	Transcriptional regulator
CEW87_RS00455	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW87_RS00470	COG0756	dUTP diphosphatase activity
CEW87_RS00475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEW87_RS00480	COG2003	Belongs to the UPF0758 family
CEW87_RS00485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEW87_RS00490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEW87_RS00495	COG1278	Cold shock
CEW87_RS00500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEW87_RS00510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEW87_RS00515	COG2224	Isocitrate lyase
CEW87_RS00530	COG2205	protein histidine kinase activity
CEW87_RS00535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEW87_RS00540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEW87_RS00560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEW87_RS00565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEW87_RS00570	COG0739	heme binding
CEW87_RS00575	COG0316	Belongs to the HesB IscA family
CEW87_RS00580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEW87_RS00585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEW87_RS00595	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CEW87_RS00605	COG0494	nUDIX hydrolase
CEW87_RS00610	COG0442	prolyl-tRNA aminoacylation
CEW87_RS00615	COG0741	lytic transglycosylase activity
CEW87_RS00630	COG0312	modulator of DNA gyrase
CEW87_RS00635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS00645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEW87_RS00650	COG3025	triphosphatase activity
CEW87_RS00650	COG5607	PFAM CHAD domain containing protein
CEW87_RS00670	COG0482	sulfurtransferase activity
CEW87_RS00700	COG0429	hydrolase of the alpha beta-hydrolase fold
CEW87_RS00710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW87_RS00715	COG2096	Adenosyltransferase
CEW87_RS00720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEW87_RS00730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEW87_RS00735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEW87_RS00740	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CEW87_RS00745	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEW87_RS00750	COG3028	Belongs to the UPF0307 family
CEW87_RS00755	COG0312	modulator of DNA gyrase
CEW87_RS00765	COG2951	lytic endotransglycosylase activity
CEW87_RS00780	COG1346	cytolysis
CEW87_RS00790	COG5002	protein histidine kinase activity
CEW87_RS00795	COG0745	RESPONSE REGULATOR receiver
CEW87_RS00805	COG4251	negative regulation of phosphorylation
CEW87_RS00815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEW87_RS00825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEW87_RS00830	COG0628	permease
CEW87_RS00835	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEW87_RS00845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEW87_RS00855	COG1175	transmembrane transport
CEW87_RS00870	COG1349	DNA-binding transcription factor activity
CEW87_RS00875	COG0617	tRNA 3'-terminal CCA addition
CEW87_RS00900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW87_RS00915	COG0247	lactate metabolic process
CEW87_RS00920	COG0277	FAD linked oxidase domain protein
CEW87_RS00925	COG0277	FAD linked oxidase domain protein
CEW87_RS00940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEW87_RS00945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEW87_RS00950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEW87_RS00955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEW87_RS00985	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEW87_RS01000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW87_RS01010	COG0604	alcohol dehydrogenase
CEW87_RS01020	COG1704	LemA family
CEW87_RS01030	COG0488	(ABC) transporter
CEW87_RS01050	COG0739	heme binding
CEW87_RS01050	COG1196	nuclear chromosome segregation
CEW87_RS01050	COG0741	lytic transglycosylase activity
CEW87_RS01070	COG2204	response regulator
CEW87_RS01075	COG4191	Histidine kinase
CEW87_RS01080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW87_RS01085	COG2030	dehydratase
CEW87_RS01100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEW87_RS01120	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CEW87_RS01155	COG0633	Ferredoxin
CEW87_RS01160	COG0426	domain, Protein
CEW87_RS01170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEW87_RS01195	COG4657	Part of a membrane complex involved in electron transport
CEW87_RS01200	COG2878	Part of a membrane complex involved in electron transport
CEW87_RS01205	COG4656	Part of a membrane complex involved in electron transport
CEW87_RS01215	COG4659	FMN binding
CEW87_RS01225	COG2914	Belongs to the UPF0125 (RnfH) family
CEW87_RS01255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEW87_RS01265	COG4536	flavin adenine dinucleotide binding
CEW87_RS01280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEW87_RS01295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEW87_RS01310	COG0733	neurotransmitter:sodium symporter activity
CEW87_RS01315	COG1522	sequence-specific DNA binding
CEW87_RS01325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW87_RS01335	COG0134	indole-3-glycerol-phosphate synthase activity
CEW87_RS01340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW87_RS01345	COG0512	Glutamine amidotransferase of anthranilate synthase
CEW87_RS01395	COG0629	single-stranded DNA binding
CEW87_RS01400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEW87_RS01585	COG1569	PIN domain
CEW87_RS01590	COG3311	Transcriptional regulator
CEW87_RS01645	COG2003	Belongs to the UPF0758 family
CEW87_RS01730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS01735	COG0842	Transport permease protein
CEW87_RS01735	COG1129	ABC transporter
CEW87_RS01740	COG0842	Transport permease protein
CEW87_RS01750	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS01770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW87_RS01775	COG0786	glutamate:sodium symporter activity
CEW87_RS01780	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW87_RS01785	COG0589	response to stress
CEW87_RS01805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEW87_RS01810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEW87_RS01815	COG0583	DNA-binding transcription factor activity
CEW87_RS01820	COG1396	sequence-specific DNA binding
CEW87_RS01830	COG0582	viral genome integration into host DNA
CEW87_RS01840	COG0546	phosphoglycolate phosphatase activity
CEW87_RS01845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEW87_RS01850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEW87_RS01855	COG5212	phosphodiesterase
CEW87_RS01870	COG3344	reverse transcriptase
CEW87_RS01875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEW87_RS01880	COG0045	succinate-CoA ligase (ADP-forming) activity
CEW87_RS01895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEW87_RS01905	COG0805	protein transport
CEW87_RS01910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEW87_RS01915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEW87_RS01925	COG0140	phosphoribosyl-ATP diphosphatase activity
CEW87_RS01930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEW87_RS01935	COG0107	imidazoleglycerol-phosphate synthase activity
CEW87_RS01940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEW87_RS01945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEW87_RS01950	COG0131	Imidazoleglycerol-phosphate dehydratase
CEW87_RS01955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW87_RS01960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEW87_RS01965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEW87_RS01970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW87_RS01975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEW87_RS01985	COG0842	Transport permease protein
CEW87_RS01990	COG1131	(ABC) transporter
CEW87_RS02010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEW87_RS02015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEW87_RS02020	COG1127	ABC transporter
CEW87_RS02085	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEW87_RS02090	COG1024	Enoyl-CoA hydratase
CEW87_RS02105	COG0204	Acyl-transferase
CEW87_RS02110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEW87_RS02115	COG0751	glycine-tRNA ligase activity
CEW87_RS02120	COG0752	glycyl-tRNA synthetase alpha subunit
CEW87_RS02125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEW87_RS02130	COG4535	Mg2 and Co2 transporter CorC
CEW87_RS02135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEW87_RS02140	COG1702	phosphate starvation-inducible protein PhoH
CEW87_RS02145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEW87_RS02165	COG1739	Uncharacterized protein family UPF0029
CEW87_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS02175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEW87_RS02180	COG0583	DNA-binding transcription factor activity
CEW87_RS02190	COG2308	Evidence 4 Homologs of previously reported genes of
CEW87_RS02215	COG0511	ligase activity, forming carbon-carbon bonds
CEW87_RS02220	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEW87_RS02225	COG1607	acyl-coa hydrolase
CEW87_RS02230	COG3634	alkyl hydroperoxide reductase activity
CEW87_RS02245	COG2177	Part of the ABC transporter FtsEX involved in
CEW87_RS02250	COG2884	Cell division ATP-binding protein ftsE
CEW87_RS02260	COG0612	Peptidase, M16
CEW87_RS02265	COG0612	Peptidase, M16
CEW87_RS02270	COG0742	ribosomal rna small subunit methyltransferase
CEW87_RS02275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEW87_RS02280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEW87_RS02285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CEW87_RS02290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEW87_RS02300	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEW87_RS02305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEW87_RS02315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW87_RS02320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEW87_RS02325	COG0193	aminoacyl-tRNA hydrolase activity
CEW87_RS02330	COG0012	GTP binding
CEW87_RS02335	COG3002	Belongs to the UPF0753 family
CEW87_RS02340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW87_RS02350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEW87_RS02355	COG2169	Transcriptional regulator
CEW87_RS02355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEW87_RS02370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEW87_RS02375	COG1053	succinate dehydrogenase
CEW87_RS02395	COG4263	nitrous-oxide reductase activity
CEW87_RS02420	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CEW87_RS02445	COG3245	cytochrome
CEW87_RS02465	COG0488	(ABC) transporter
CEW87_RS02470	COG0583	DNA-binding transcription factor activity
CEW87_RS02475	COG0477	Major facilitator Superfamily
CEW87_RS02525	COG3181	Tripartite tricarboxylate transporter family receptor
CEW87_RS02530	COG0251	oxidation-reduction process
CEW87_RS02535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS02590	COG3459	Glycosyltransferase 36 associated
CEW87_RS02605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEW87_RS02610	COG0798	PFAM Bile acid sodium symporter
CEW87_RS02625	COG0583	DNA-binding transcription factor activity
CEW87_RS02630	COG1741	Belongs to the pirin family
CEW87_RS02650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEW87_RS02655	COG3842	ATPase activity
CEW87_RS02660	COG1177	transmembrane transport
CEW87_RS02665	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW87_RS02675	COG1349	DNA-binding transcription factor activity
CEW87_RS02680	COG2267	carboxylic ester hydrolase activity
CEW87_RS02685	COG0697	spore germination
CEW87_RS02690	COG0583	DNA-binding transcription factor activity
CEW87_RS02700	COG5002	protein histidine kinase activity
CEW87_RS02700	COG3447	MASE1 domain protein
CEW87_RS02700	COG5001	Diguanylate cyclase
CEW87_RS02720	COG0463	Glycosyl transferase, family 2
CEW87_RS02765	COG0436	Aminotransferase
CEW87_RS02770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CEW87_RS02785	COG2084	Dehydrogenase
CEW87_RS02790	COG2084	Dehydrogenase
CEW87_RS02795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW87_RS02805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEW87_RS02815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEW87_RS02845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEW87_RS02855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEW87_RS02865	COG0784	Response regulator, receiver
CEW87_RS02870	COG4251	negative regulation of phosphorylation
CEW87_RS02880	COG0629	single-stranded DNA binding
CEW87_RS02885	COG2814	Major facilitator Superfamily
CEW87_RS02900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEW87_RS02905	COG0203	ribosomal protein L17
CEW87_RS02910	COG0202	RNA polymerase activity
CEW87_RS02915	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEW87_RS02920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEW87_RS02925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEW87_RS02930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEW87_RS02935	COG0201	protein transport
CEW87_RS02940	COG0200	Binds to the 23S rRNA
CEW87_RS02945	COG1841	ribosomal large subunit assembly
CEW87_RS02950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEW87_RS02955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEW87_RS02960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEW87_RS02965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEW87_RS02970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEW87_RS02975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEW87_RS02980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEW87_RS02985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEW87_RS02990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEW87_RS02995	COG0255	Belongs to the universal ribosomal protein uL29 family
CEW87_RS03000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEW87_RS03005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEW87_RS03010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEW87_RS03015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEW87_RS03020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEW87_RS03025	COG0089	rRNA binding
CEW87_RS03030	COG0088	Forms part of the polypeptide exit tunnel
CEW87_RS03035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEW87_RS03040	COG0051	transcription antitermination factor activity, RNA binding
CEW87_RS03045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEW87_RS03050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEW87_RS03055	COG0049	tRNA binding
CEW87_RS03060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEW87_RS03065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEW87_RS03070	COG0085	RNA polymerase activity
CEW87_RS03075	COG0222	ribosome binding
CEW87_RS03080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEW87_RS03085	COG0081	regulation of translation
CEW87_RS03090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEW87_RS03100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEW87_RS03110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEW87_RS03135	COG5265	(ABC) transporter
CEW87_RS03160	COG0252	asparaginase activity
CEW87_RS03165	COG0583	DNA-binding transcription factor activity
CEW87_RS03170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW87_RS03180	COG0175	sulfate reduction
CEW87_RS03185	COG0175	sulfate reduction
CEW87_RS03190	COG2895	sulfate adenylyltransferase (ATP) activity
CEW87_RS03205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEW87_RS03215	COG0501	Belongs to the peptidase M48B family
CEW87_RS03220	COG0513	Belongs to the DEAD box helicase family
CEW87_RS03225	COG0778	Nitroreductase
CEW87_RS03240	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CEW87_RS03250	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CEW87_RS03285	COG0427	acetyl-CoA hydrolase
CEW87_RS03335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEW87_RS03340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW87_RS03345	COG1538	Outer membrane efflux protein
CEW87_RS03370	COG2818	Glycosylase
CEW87_RS03380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEW87_RS03385	COG0443	Heat shock 70 kDa protein
CEW87_RS03390	COG2070	2-Nitropropane dioxygenase
CEW87_RS03440	COG1764	response to oxidative stress
CEW87_RS03450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEW87_RS03480	COG2186	Transcriptional regulator
CEW87_RS03495	COG0583	DNA-binding transcription factor activity
CEW87_RS03520	COG2205	protein histidine kinase activity
CEW87_RS03520	COG0784	Response regulator, receiver
CEW87_RS03520	COG5002	protein histidine kinase activity
CEW87_RS03555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEW87_RS03565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW87_RS03580	COG0067	glutamate synthase
CEW87_RS03580	COG0070	glutamate synthase
CEW87_RS03580	COG0069	glutamate synthase activity
CEW87_RS03585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEW87_RS03590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEW87_RS03595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEW87_RS03630	COG1965	Belongs to the frataxin family
CEW87_RS03660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEW87_RS03665	COG0284	orotidine-5'-phosphate decarboxylase activity
CEW87_RS03670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CEW87_RS03675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEW87_RS03685	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CEW87_RS03715	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEW87_RS03730	COG1805	sodium ion transport
CEW87_RS03740	COG0183	Belongs to the thiolase family
CEW87_RS03745	COG1024	Enoyl-CoA hydratase
CEW87_RS03745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS03750	COG2067	long-chain fatty acid transport protein
CEW87_RS03760	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS03760	COG1024	Enoyl-CoA hydratase
CEW87_RS03770	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS03795	COG0523	cobalamin synthesis protein
CEW87_RS03800	COG0277	FAD linked oxidase domain protein
CEW87_RS03820	COG2197	response regulator
CEW87_RS03835	COG2205	protein histidine kinase activity
CEW87_RS03835	COG2198	Histidine kinase
CEW87_RS03835	COG0784	Response regulator, receiver
CEW87_RS03845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW87_RS03880	COG1022	Amp-dependent synthetase and ligase
CEW87_RS03985	COG4373	Mu-like prophage FluMu protein gp28
CEW87_RS04030	COG3023	N-Acetylmuramoyl-L-alanine amidase
CEW87_RS04070	COG3409	Peptidoglycan-binding domain 1 protein
CEW87_RS04070	COG3267	Type II secretory pathway component ExeA
CEW87_RS04090	COG4396	Host-nuclease inhibitor protein Gam
CEW87_RS04120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW87_RS04120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW87_RS04120	COG1703	isobutyryl-CoA mutase activity
CEW87_RS04145	COG2321	neutral zinc metallopeptidase
CEW87_RS04150	COG1509	lysine 2,3-aminomutase activity
CEW87_RS04160	COG4770	biotin carboxylase activity
CEW87_RS04165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEW87_RS04170	COG1703	isobutyryl-CoA mutase activity
CEW87_RS04175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW87_RS04175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW87_RS04180	COG1802	Transcriptional regulator
CEW87_RS04185	COG1253	flavin adenine dinucleotide binding
CEW87_RS04190	COG0114	fumarate hydratase activity
CEW87_RS04195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW87_RS04200	COG3162	membrane
CEW87_RS04205	COG1024	Enoyl-CoA hydratase
CEW87_RS04210	COG1492	cobalamin metabolic process
CEW87_RS04215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEW87_RS04220	COG1999	signal sequence binding
CEW87_RS04225	COG0109	protoheme IX farnesyltransferase activity
CEW87_RS04260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CEW87_RS04265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEW87_RS04280	COG4221	oxidoreductase activity
CEW87_RS04300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEW87_RS04315	COG1469	GTP cyclohydrolase I activity
CEW87_RS04345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW87_RS04350	COG1832	CoA-binding protein
CEW87_RS04375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW87_RS04380	COG3568	Endonuclease Exonuclease Phosphatase
CEW87_RS04385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEW87_RS04400	COG0174	glutamine synthetase
CEW87_RS04410	COG3852	Histidine kinase
CEW87_RS04425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CEW87_RS04435	COG0237	dephospho-CoA kinase activity
CEW87_RS04440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEW87_RS04445	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CEW87_RS04450	COG0494	nUDIX hydrolase
CEW87_RS04460	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEW87_RS04465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEW87_RS04470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW87_RS04500	COG0305	Participates in initiation and elongation during chromosome replication
CEW87_RS04505	COG0359	binds to the 23S rRNA
CEW87_RS04510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEW87_RS04515	COG2965	DNA replication, synthesis of RNA primer
CEW87_RS04520	COG0360	Binds together with S18 to 16S ribosomal RNA
CEW87_RS04530	COG1643	Atp-dependent helicase
CEW87_RS04550	COG1968	undecaprenyl-diphosphatase activity
CEW87_RS04555	COG3150	esterase
CEW87_RS04560	COG2226	methyltransferase
CEW87_RS04565	COG2962	Rard protein
CEW87_RS04570	COG0557	exoribonuclease II activity
CEW87_RS04580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEW87_RS04585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEW87_RS04590	COG2239	Acts as a magnesium transporter
CEW87_RS04595	COG2119	membrane
CEW87_RS04600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEW87_RS04605	COG0352	thiamine-phosphate diphosphorylase activity
CEW87_RS04615	COG1773	rubredoxin
CEW87_RS04635	COG0840	transmembrane signaling receptor activity
CEW87_RS04640	COG2198	Histidine kinase
CEW87_RS04640	COG0643	Histidine kinase
CEW87_RS04645	COG0415	Belongs to the DNA photolyase family
CEW87_RS04650	COG1678	Uncharacterized ACR, COG1678
CEW87_RS04655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEW87_RS04660	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEW87_RS04665	COG0540	Belongs to the ATCase OTCase family
CEW87_RS04675	COG1872	DUF167
CEW87_RS04680	COG0762	integral membrane protein
CEW87_RS04725	COG0437	4 iron, 4 sulfur cluster binding
CEW87_RS04730	COG3383	formate dehydrogenase (NAD+) activity
CEW87_RS04770	COG0746	molybdenum cofactor guanylyltransferase activity
CEW87_RS04780	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEW87_RS04785	COG4191	Histidine kinase
CEW87_RS04795	COG1981	membrane
CEW87_RS04810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEW87_RS04815	COG5002	protein histidine kinase activity
CEW87_RS04825	COG4654	Cytochrome c, class I
CEW87_RS04840	COG3842	ATPase activity
CEW87_RS04855	COG4303	Ethanolamine ammonia lyase large subunit
CEW87_RS04860	COG4302	ethanolamine ammonia-lyase activity
CEW87_RS04870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEW87_RS04875	COG0830	nickel cation binding
CEW87_RS04880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CEW87_RS04885	COG0804	urea catabolic process
CEW87_RS04890	COG0832	Belongs to the urease beta subunit family
CEW87_RS04900	COG0831	urea catabolic process
CEW87_RS04905	COG0829	nickel cation binding
CEW87_RS04910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEW87_RS04910	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEW87_RS04915	COG0659	secondary active sulfate transmembrane transporter activity
CEW87_RS04965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW87_RS04970	COG1116	anion transmembrane transporter activity
CEW87_RS04975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW87_RS05030	COG3047	cAMP biosynthetic process
CEW87_RS05035	COG0513	Belongs to the DEAD box helicase family
CEW87_RS05045	COG1451	nucleotide metabolic process
CEW87_RS05050	COG1132	(ABC) transporter
CEW87_RS05055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW87_RS05065	COG5002	protein histidine kinase activity
CEW87_RS05065	COG2198	Histidine kinase
CEW87_RS05065	COG0784	Response regulator, receiver
CEW87_RS05070	COG1538	Outer membrane efflux protein
CEW87_RS05080	COG2200	EAL domain
CEW87_RS05080	COG2199	diguanylate cyclase activity
CEW87_RS05080	COG2203	Gaf domain
CEW87_RS05095	COG2197	response regulator
CEW87_RS05100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS05105	COG2274	protein secretion by the type I secretion system
CEW87_RS05125	COG1136	(ABC) transporter
CEW87_RS05135	COG0735	belongs to the Fur family
CEW87_RS05140	COG1121	(ABC) transporter
CEW87_RS05150	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEW87_RS05155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEW87_RS05160	COG1074	ATP-dependent DNA helicase activity
CEW87_RS05165	COG0688	phosphatidylethanolamine metabolic process
CEW87_RS05170	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEW87_RS05175	COG3530	Putative quorum-sensing-regulated virulence factor
CEW87_RS05180	COG2095	MarC family integral membrane protein
CEW87_RS05190	COG1160	GTP binding
CEW87_RS05200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEW87_RS05215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEW87_RS05220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS05230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEW87_RS05250	COG0419	ATPase involved in DNA repair
CEW87_RS05255	COG0420	3'-5' exonuclease activity
CEW87_RS05270	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS05280	COG0432	Pfam Uncharacterised protein family UPF0047
CEW87_RS05295	COG0616	signal peptide processing
CEW87_RS05300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEW87_RS05305	COG2022	thiamine diphosphate biosynthetic process
CEW87_RS05315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEW87_RS05325	COG1126	abc transporter atp-binding protein
CEW87_RS05330	COG0765	amino acid transport
CEW87_RS05335	COG4597	amino acid ABC transporter
CEW87_RS05340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW87_RS05355	COG2814	Major facilitator Superfamily
CEW87_RS05375	COG0288	reversible hydration of carbon dioxide
CEW87_RS05380	COG1940	carbohydrate kinase activity
CEW87_RS05385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEW87_RS05390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEW87_RS05400	COG0569	domain protein
CEW87_RS05405	COG2204	response regulator
CEW87_RS05410	COG5000	phosphorelay sensor kinase activity
CEW87_RS05430	COG4106	trans-aconitate 2-methyltransferase activity
CEW87_RS05440	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEW87_RS05445	COG0706	membrane insertase activity
CEW87_RS05450	COG0594	ribonuclease P activity
CEW87_RS05455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEW87_RS05460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEW87_RS05510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEW87_RS05560	COG2131	deaminase
CEW87_RS05590	COG0583	DNA-binding transcription factor activity
CEW87_RS05595	COG2814	Major facilitator Superfamily
CEW87_RS05600	COG0527	aspartate kinase activity
CEW87_RS05610	COG1131	(ABC) transporter
CEW87_RS05615	COG0842	Transport permease protein
CEW87_RS05630	COG0583	DNA-binding transcription factor activity
CEW87_RS05660	COG3040	lipid binding
CEW87_RS05695	COG3842	ATPase activity
CEW87_RS05705	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW87_RS05710	COG1177	transmembrane transport
CEW87_RS05725	COG0861	Integral membrane protein TerC family
CEW87_RS05730	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEW87_RS05735	COG1984	allophanate hydrolase subunit 2
CEW87_RS05740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEW87_RS05765	COG0783	Belongs to the Dps family
CEW87_RS05775	COG4206	TonB-dependent receptor
CEW87_RS05780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW87_RS05785	COG3706	GGDEF domain
CEW87_RS05795	COG3909	cytochrome
CEW87_RS05805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEW87_RS05815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEW87_RS05825	COG1187	pseudouridine synthase activity
CEW87_RS05835	COG2974	May be involved in recombination
CEW87_RS05840	COG1454	alcohol dehydrogenase
CEW87_RS05855	COG1454	alcohol dehydrogenase
CEW87_RS05860	COG0410	ABC transporter
CEW87_RS05865	COG1137	ATPase activity
CEW87_RS05875	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW87_RS05890	COG2204	response regulator
CEW87_RS05895	COG3852	Histidine kinase
CEW87_RS05905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEW87_RS05915	COG2922	Belongs to the Smg family
CEW87_RS05920	COG0758	DNA mediated transformation
CEW87_RS05930	COG0242	peptide deformylase activity
CEW87_RS05935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW87_RS05940	COG0501	Belongs to the peptidase M48B family
CEW87_RS05945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW87_RS05950	COG1305	Transglutaminase-like
CEW87_RS05960	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEW87_RS05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW87_RS05975	COG2205	protein histidine kinase activity
CEW87_RS05975	COG0784	Response regulator, receiver
CEW87_RS05990	COG0653	protein targeting
CEW87_RS06010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEW87_RS06020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS06030	COG0583	DNA-binding transcription factor activity
CEW87_RS06035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEW87_RS06045	COG0583	DNA-binding transcription factor activity
CEW87_RS06065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW87_RS06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW87_RS06090	COG0431	NADPH-dependent FMN reductase
CEW87_RS06095	COG1393	Belongs to the ArsC family
CEW87_RS06115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW87_RS06145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS06150	COG0577	efflux transmembrane transporter activity
CEW87_RS06150	COG1136	(ABC) transporter
CEW87_RS06155	COG0577	efflux transmembrane transporter activity
CEW87_RS06155	COG1136	(ABC) transporter
CEW87_RS06160	COG0535	radical SAM domain protein
CEW87_RS06170	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CEW87_RS06175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEW87_RS06195	COG0583	DNA-binding transcription factor activity
CEW87_RS06200	COG3437	response regulator, receiver
CEW87_RS06210	COG5002	protein histidine kinase activity
CEW87_RS06210	COG0784	Response regulator, receiver
CEW87_RS06210	COG2205	protein histidine kinase activity
CEW87_RS06235	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW87_RS06275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CEW87_RS06275	COG3608	succinylglutamate desuccinylase aspartoacylase
CEW87_RS06300	COG0633	Ferredoxin
CEW87_RS06300	COG3217	Mosc domain protein beta barrel domain protein
CEW87_RS06305	COG3706	GGDEF domain
CEW87_RS06330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CEW87_RS06370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW87_RS06395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW87_RS06400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW87_RS06405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW87_RS06405	COG1116	anion transmembrane transporter activity
CEW87_RS06410	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CEW87_RS06430	COG0697	spore germination
CEW87_RS06435	COG0683	leucine binding
CEW87_RS06445	COG3437	response regulator, receiver
CEW87_RS06450	COG0445	tRNA wobble uridine modification
CEW87_RS06455	COG0357	Ribosomal RNA small subunit methyltransferase G
CEW87_RS06460	COG1192	Involved in chromosome partitioning
CEW87_RS06465	COG1475	DNA binding
CEW87_RS06490	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW87_RS06500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW87_RS06505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW87_RS06510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW87_RS06515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEW87_RS06520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW87_RS06525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEW87_RS06540	COG2226	methyltransferase
CEW87_RS06550	COG0745	RESPONSE REGULATOR receiver
CEW87_RS06570	COG0121	glutamine amidotransferase
CEW87_RS06575	COG2391	methyltransferase activity
CEW87_RS06585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW87_RS06595	COG0154	amidase activity
CEW87_RS06600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW87_RS06605	COG1077	Cell shape determining protein MreB Mrl
CEW87_RS06620	COG0768	penicillin binding
CEW87_RS06625	COG0772	Belongs to the SEDS family
CEW87_RS06635	COG1686	Belongs to the peptidase S11 family
CEW87_RS06645	COG2921	Belongs to the UPF0250 family
CEW87_RS06650	COG0321	lipoyl(octanoyl) transferase activity
CEW87_RS06655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEW87_RS06670	COG0210	DNA helicase
CEW87_RS06680	COG3706	GGDEF domain
CEW87_RS06685	COG0741	lytic transglycosylase activity
CEW87_RS06695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW87_RS06710	COG1309	transcriptional regulator
CEW87_RS06715	COG0604	alcohol dehydrogenase
CEW87_RS06760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEW87_RS06765	COG0022	dehydrogenase e1 component
CEW87_RS06775	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW87_RS06780	COG0095	Lipoate-protein ligase
CEW87_RS06805	COG3284	Transcriptional regulator
CEW87_RS06820	COG4628	conserved protein (DUF2132)
CEW87_RS06825	COG2066	Belongs to the glutaminase family
CEW87_RS06855	COG1063	alcohol dehydrogenase
CEW87_RS06865	COG1397	ADP-ribosylglycohydrolase
CEW87_RS06900	COG3621	Patatin-like phospholipase
CEW87_RS06980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEW87_RS06985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS06995	COG0471	metal ion transport
CEW87_RS07015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEW87_RS07025	COG1053	succinate dehydrogenase
CEW87_RS07035	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS07060	COG0583	DNA-binding transcription factor activity
CEW87_RS07090	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CEW87_RS07100	COG0668	transmembrane transport
CEW87_RS07140	COG3264	Mechanosensitive ion channel
CEW87_RS07140	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEW87_RS07180	COG1518	maintenance of DNA repeat elements
CEW87_RS07185	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CEW87_RS07205	COG0582	viral genome integration into host DNA
CEW87_RS07225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEW87_RS07230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEW87_RS07235	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEW87_RS07245	COG2815	serine threonine protein kinase
CEW87_RS07245	COG0515	serine threonine protein kinase
CEW87_RS07250	COG1561	YicC-like family, N-terminal region
CEW87_RS07270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS07290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEW87_RS07310	COG5002	protein histidine kinase activity
CEW87_RS07310	COG2198	Histidine kinase
CEW87_RS07310	COG0784	Response regulator, receiver
CEW87_RS07320	COG0194	GDP metabolic process
CEW87_RS07325	COG1758	RNA polymerase activity
CEW87_RS07330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW87_RS07340	COG2226	methyltransferase
CEW87_RS07355	COG3850	Histidine kinase
CEW87_RS07360	COG2197	response regulator
CEW87_RS07375	COG0243	molybdopterin cofactor binding
CEW87_RS07380	COG0437	4 iron, 4 sulfur cluster binding
CEW87_RS07385	COG0348	domain, Protein
CEW87_RS07390	COG3043	anaerobic respiration
CEW87_RS07395	COG3005	denitrification pathway
CEW87_RS07400	COG4133	protoheme IX ABC transporter activity
CEW87_RS07405	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEW87_RS07420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEW87_RS07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW87_RS07445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEW87_RS07485	COG0475	glutathione-regulated potassium exporter activity
CEW87_RS07505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEW87_RS07510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEW87_RS07520	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEW87_RS07570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW87_RS07580	COG1131	(ABC) transporter
CEW87_RS07595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW87_RS07640	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS07645	COG1024	Enoyl-CoA hydratase
CEW87_RS07650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS07655	COG2050	protein possibly involved in aromatic compounds catabolism
CEW87_RS07665	COG3396	Phenylacetate-CoA oxygenase
CEW87_RS07670	COG3460	Phenylacetate-CoA oxygenase
CEW87_RS07675	COG3396	Phenylacetate-CoA oxygenase
CEW87_RS07680	COG2151	metal-sulfur cluster biosynthetic enzyme
CEW87_RS07685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS07695	COG0183	Belongs to the thiolase family
CEW87_RS07730	COG0513	Belongs to the DEAD box helicase family
CEW87_RS07735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW87_RS07740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEW87_RS07755	COG4232	protein-disulfide reductase activity
CEW87_RS07795	COG0534	Mate efflux family protein
CEW87_RS07810	COG2837	iron assimilation
CEW87_RS07815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEW87_RS07825	COG3321	synthase
CEW87_RS07825	COG0604	alcohol dehydrogenase
CEW87_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS07830	COG0583	DNA-binding transcription factor activity
CEW87_RS07835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW87_RS07840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW87_RS07850	COG0210	DNA helicase
CEW87_RS07870	COG3706	GGDEF domain
CEW87_RS07870	COG2203	Gaf domain
CEW87_RS07870	COG5001	Diguanylate cyclase
CEW87_RS07870	COG4251	negative regulation of phosphorylation
CEW87_RS07920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS07925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS07940	COG2824	Alkylphosphonate utilization operon protein PhnA
CEW87_RS07945	COG0366	Alpha amylase catalytic
CEW87_RS07955	COG4178	(ABC) transporter
CEW87_RS07965	COG0366	Alpha amylase catalytic
CEW87_RS07975	COG3706	GGDEF domain
CEW87_RS07985	COG0210	DNA helicase
CEW87_RS08010	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEW87_RS08020	COG2703	oxygen carrier activity
CEW87_RS08025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW87_RS08035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW87_RS08040	COG0235	Class ii aldolase
CEW87_RS08060	COG3971	2-oxopent-4-enoate hydratase activity
CEW87_RS08070	COG3384	dioxygenase
CEW87_RS08075	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS08100	COG1846	Transcriptional regulator
CEW87_RS08115	COG1024	Enoyl-CoA hydratase
CEW87_RS08125	COG1024	Enoyl-CoA hydratase
CEW87_RS08130	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW87_RS08145	COG1131	(ABC) transporter
CEW87_RS08150	COG0625	glutathione transferase activity
CEW87_RS08175	COG0583	DNA-binding transcription factor activity
CEW87_RS08200	COG0642	Histidine kinase
CEW87_RS08220	COG0347	Belongs to the P(II) protein family
CEW87_RS08225	COG0004	ammonium transporteR
CEW87_RS08250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW87_RS08250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW87_RS08260	COG0174	glutamine synthetase
CEW87_RS08265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEW87_RS08275	COG0069	glutamate synthase activity
CEW87_RS08280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW87_RS08285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEW87_RS08300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS08320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW87_RS08330	COG3850	Histidine kinase
CEW87_RS08335	COG2197	response regulator
CEW87_RS08350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW87_RS08375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW87_RS08380	COG1522	sequence-specific DNA binding
CEW87_RS08390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS08405	COG3154	lipid carrier protein
CEW87_RS08410	COG0826	peptidase U32
CEW87_RS08415	COG0826	peptidase U32
CEW87_RS08425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW87_RS08430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEW87_RS08435	COG0018	arginyl-trna synthetase
CEW87_RS08445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEW87_RS08450	COG0300	oxidoreductase activity
CEW87_RS08470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEW87_RS08480	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW87_RS08500	COG0288	reversible hydration of carbon dioxide
CEW87_RS08505	COG0183	Belongs to the thiolase family
CEW87_RS08510	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS08520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW87_RS08535	COG3001	Fructosamine kinase
CEW87_RS08545	COG1309	transcriptional regulator
CEW87_RS08560	COG0625	glutathione transferase activity
CEW87_RS08580	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS08595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEW87_RS08600	COG1024	Enoyl-CoA hydratase
CEW87_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS08635	COG1660	Displays ATPase and GTPase activities
CEW87_RS08655	COG0412	Dienelactone hydrolase
CEW87_RS08660	COG1611	Belongs to the LOG family
CEW87_RS08715	COG1522	sequence-specific DNA binding
CEW87_RS08720	COG0189	ligase activity
CEW87_RS08735	COG0697	spore germination
CEW87_RS08755	COG0788	formyltetrahydrofolate deformylase activity
CEW87_RS08760	COG0004	ammonium transporteR
CEW87_RS08765	COG0347	Belongs to the P(II) protein family
CEW87_RS08780	COG0606	chelatase, subunit chli
CEW87_RS08810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEW87_RS08855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEW87_RS08900	COG0606	chelatase, subunit chli
CEW87_RS08910	COG2814	Major facilitator Superfamily
CEW87_RS09040	COG0604	alcohol dehydrogenase
CEW87_RS09060	COG1595	DNA-templated transcription, initiation
CEW87_RS09075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW87_RS09080	COG3284	Transcriptional regulator
CEW87_RS09085	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS09130	COG2329	Antibiotic biosynthesis monooxygenase
CEW87_RS09150	COG1683	Conserved Protein
CEW87_RS09155	COG2076	Multidrug Resistance protein
CEW87_RS09165	COG0583	DNA-binding transcription factor activity
CEW87_RS09170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW87_RS09180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW87_RS09185	COG3876	Protein conserved in bacteria
CEW87_RS09200	COG0668	transmembrane transport
CEW87_RS09220	COG0180	Tryptophanyl-tRNA synthetase
CEW87_RS09230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEW87_RS09235	COG0726	polysaccharide deacetylase
CEW87_RS09275	COG1132	(ABC) transporter
CEW87_RS09285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CEW87_RS09290	COG0859	PFAM glycosyl transferase family 9
CEW87_RS09295	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS09300	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS09305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEW87_RS09320	COG0129	dihydroxy-acid dehydratase activity
CEW87_RS09345	COG2358	TRAP transporter, solute receptor (TAXI family
CEW87_RS09355	COG0745	RESPONSE REGULATOR receiver
CEW87_RS09360	COG2205	protein histidine kinase activity
CEW87_RS09370	COG1280	lysine exporter protein (LysE YggA)
CEW87_RS09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW87_RS09390	COG1970	mechanosensitive ion channel activity
CEW87_RS09395	COG2860	membrane
CEW87_RS09405	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW87_RS09435	COG1194	a g-specific adenine glycosylase
CEW87_RS09440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW87_RS09445	COG3706	GGDEF domain
CEW87_RS09450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CEW87_RS09460	COG1132	(ABC) transporter
CEW87_RS09465	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS09485	COG1215	transferase activity, transferring glycosyl groups
CEW87_RS09500	COG1368	sulfuric ester hydrolase activity
CEW87_RS09520	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS09525	COG0859	PFAM glycosyl transferase family 9
CEW87_RS09535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW87_RS09540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEW87_RS09540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CEW87_RS09550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEW87_RS09555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEW87_RS09565	COG4206	TonB-dependent receptor
CEW87_RS09570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEW87_RS09575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEW87_RS09585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEW87_RS09585	COG1648	precorrin-2 dehydrogenase activity
CEW87_RS09590	COG1797	cobyrinic acid a,c-diamide synthase activity
CEW87_RS09595	COG1902	pentaerythritol trinitrate reductase activity
CEW87_RS09615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEW87_RS09620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW87_RS09625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW87_RS09630	COG0583	DNA-binding transcription factor activity
CEW87_RS09645	COG0306	phosphate transporter
CEW87_RS09665	COG0488	(ABC) transporter
CEW87_RS09680	COG0826	peptidase U32
CEW87_RS09685	COG0004	ammonium transporteR
CEW87_RS09690	COG2226	methyltransferase
CEW87_RS09710	COG1652	LysM domain
CEW87_RS09725	COG5001	Diguanylate cyclase
CEW87_RS09730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEW87_RS09745	COG1671	Belongs to the UPF0178 family
CEW87_RS09750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEW87_RS09770	COG1024	Enoyl-CoA hydratase
CEW87_RS09780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEW87_RS09785	COG0602	queuosine metabolic process
CEW87_RS09800	COG0823	Involved in the tonB-independent uptake of proteins
CEW87_RS09810	COG0848	biopolymer transport protein
CEW87_RS09820	COG0824	Thioesterase
CEW87_RS09830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEW87_RS09835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEW87_RS09845	COG3300	MHYT domain
CEW87_RS09845	COG5001	Diguanylate cyclase
CEW87_RS09875	COG3128	pkhd-type hydroxylase
CEW87_RS09885	COG4774	siderophore transport
CEW87_RS09895	COG0577	efflux transmembrane transporter activity
CEW87_RS09895	COG1136	(ABC) transporter
CEW87_RS09900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS09945	COG5001	Diguanylate cyclase
CEW87_RS09955	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEW87_RS09960	COG3132	Protein of unknown function, DUF480
CEW87_RS09965	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CEW87_RS09985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEW87_RS10005	COG2264	protein methyltransferase activity
CEW87_RS10010	COG0439	Biotin carboxylase
CEW87_RS10015	COG0511	ligase activity, forming carbon-carbon bonds
CEW87_RS10020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEW87_RS10025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW87_RS10035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEW87_RS10045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEW87_RS10050	COG0792	nuclease activity
CEW87_RS10060	COG0418	dihydroorotase activity
CEW87_RS10075	COG2001	Belongs to the MraZ family
CEW87_RS10080	COG0275	rRNA processing
CEW87_RS10095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEW87_RS10100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEW87_RS10105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEW87_RS10110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEW87_RS10115	COG0772	Belongs to the SEDS family
CEW87_RS10120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEW87_RS10125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEW87_RS10130	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEW87_RS10135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEW87_RS10150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEW87_RS10165	COG0653	protein targeting
CEW87_RS10170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEW87_RS10175	COG3158	transport of potassium into the cell
CEW87_RS10180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEW87_RS10190	COG2967	ApaG domain
CEW87_RS10205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEW87_RS10210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEW87_RS10215	COG1862	Preprotein translocase
CEW87_RS10220	COG0343	queuine tRNA-ribosyltransferase activity
CEW87_RS10225	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEW87_RS10235	COG0583	DNA-binding transcription factor activity
CEW87_RS10245	COG0670	Belongs to the BI1 family
CEW87_RS10250	COG0825	malonyl-CoA metabolic process
CEW87_RS10255	COG0037	tRNA processing
CEW87_RS10285	COG1187	pseudouridine synthase activity
CEW87_RS10290	COG1253	flavin adenine dinucleotide binding
CEW87_RS10295	COG0861	Integral membrane protein TerC family
CEW87_RS10310	COG0577	efflux transmembrane transporter activity
CEW87_RS10310	COG1136	(ABC) transporter
CEW87_RS10315	COG0577	efflux transmembrane transporter activity
CEW87_RS10315	COG1136	(ABC) transporter
CEW87_RS10320	COG0577	efflux transmembrane transporter activity
CEW87_RS10320	COG1136	(ABC) transporter
CEW87_RS10330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW87_RS10335	COG0668	transmembrane transport
CEW87_RS10340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEW87_RS10350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEW87_RS10360	COG4647	ligase activity
CEW87_RS10365	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CEW87_RS10370	COG0145	ligase activity
CEW87_RS10375	COG3284	Transcriptional regulator
CEW87_RS10380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEW87_RS10385	COG0351	phosphomethylpyrimidine kinase
CEW87_RS10395	COG1136	(ABC) transporter
CEW87_RS10395	COG0577	efflux transmembrane transporter activity
CEW87_RS10420	COG0489	protein tyrosine kinase activity
CEW87_RS10430	COG3267	Type II secretory pathway component ExeA
CEW87_RS10430	COG3409	Peptidoglycan-binding domain 1 protein
CEW87_RS10460	COG0367	asparagine synthase
CEW87_RS10465	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS10470	COG0367	asparagine synthase
CEW87_RS10555	COG1216	Glycosyl transferase, family 2
CEW87_RS10595	COG2026	Addiction module toxin, RelE StbE family
CEW87_RS10605	COG0367	asparagine synthase
CEW87_RS10630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEW87_RS10650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEW87_RS10655	COG0071	Belongs to the small heat shock protein (HSP20) family
CEW87_RS10680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEW87_RS10690	COG0741	lytic transglycosylase activity
CEW87_RS10695	COG0436	Aminotransferase
CEW87_RS10700	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CEW87_RS10705	COG0281	malic enzyme
CEW87_RS10705	COG0280	phosphate acetyltransferase
CEW87_RS10725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW87_RS10725	COG2111	Na H antiporter
CEW87_RS10730	COG1006	Multisubunit Na H antiporter MnhC subunit
CEW87_RS10735	COG0651	ATP synthesis coupled electron transport
CEW87_RS10740	COG1863	multisubunit Na H antiporter MnhE subunit
CEW87_RS10745	COG2212	antiporter activity
CEW87_RS10750	COG1320	monovalent cation:proton antiporter activity
CEW87_RS10755	COG1320	monovalent cation:proton antiporter activity
CEW87_RS10760	COG2212	antiporter activity
CEW87_RS10765	COG1863	multisubunit Na H antiporter MnhE subunit
CEW87_RS10770	COG0651	ATP synthesis coupled electron transport
CEW87_RS10780	COG2111	Na H antiporter
CEW87_RS10780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW87_RS10785	COG0105	UTP biosynthetic process
CEW87_RS10790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEW87_RS10800	COG1426	Protein conserved in bacteria
CEW87_RS10805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEW87_RS10810	COG0124	histidyl-tRNA synthetase
CEW87_RS10820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEW87_RS10825	COG1160	GTP binding
CEW87_RS10830	COG1923	regulation of RNA biosynthetic process
CEW87_RS10835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEW87_RS10840	COG0330	HflC and HflK could
CEW87_RS10845	COG0330	HflC and HflK could
CEW87_RS10855	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEW87_RS10860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEW87_RS10875	COG0557	exoribonuclease II activity
CEW87_RS10880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW87_RS10885	COG3707	response regulator
CEW87_RS10890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW87_RS10890	COG1116	anion transmembrane transporter activity
CEW87_RS10895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW87_RS10905	COG1116	anion transmembrane transporter activity
CEW87_RS10915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW87_RS10930	COG0517	IMP dehydrogenase activity
CEW87_RS10935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEW87_RS10960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEW87_RS10965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEW87_RS10970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEW87_RS10975	COG0723	plastoquinol--plastocyanin reductase activity
CEW87_RS10980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEW87_RS10985	COG2857	Cytochrome c1
CEW87_RS10990	COG0625	glutathione transferase activity
CEW87_RS10995	COG2969	positive regulation of protein catabolic process
CEW87_RS11000	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS11010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS11015	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEW87_RS11025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEW87_RS11030	COG0459	protein refolding
CEW87_RS11040	COG0642	Histidine kinase
CEW87_RS11045	COG3162	membrane
CEW87_RS11070	COG3046	protein related to deoxyribodipyrimidine photolyase
CEW87_RS11075	COG0415	Belongs to the DNA photolyase family
CEW87_RS11090	COG2902	Dehydrogenase
CEW87_RS11095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEW87_RS11100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEW87_RS11105	COG2890	protein-(glutamine-N5) methyltransferase activity
CEW87_RS11110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEW87_RS11135	COG0515	serine threonine protein kinase
CEW87_RS11135	COG2815	serine threonine protein kinase
CEW87_RS11140	COG0165	Argininosuccinate lyase
CEW87_RS11185	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEW87_RS11195	COG0181	hydroxymethylbilane synthase activity
CEW87_RS11205	COG2959	enzyme of heme biosynthesis
CEW87_RS11215	COG0659	secondary active sulfate transmembrane transporter activity
CEW87_RS11220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW87_RS11220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW87_RS11230	COG0489	protein tyrosine kinase activity
CEW87_RS11235	COG0717	Belongs to the dCTP deaminase family
CEW87_RS11250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEW87_RS11395	COG3411	Ferredoxin
CEW87_RS11410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW87_RS11435	COG1858	cytochrome C peroxidase
CEW87_RS11460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEW87_RS11465	COG0393	Putative heavy-metal-binding
CEW87_RS11475	COG0217	transcriptional regulatory protein
CEW87_RS11480	COG0433	COG0433 Predicted ATPase
CEW87_RS11485	COG0697	spore germination
CEW87_RS11495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEW87_RS11500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CEW87_RS11505	COG3153	acetyltransferase
CEW87_RS11505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS11510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS11510	COG3153	acetyltransferase
CEW87_RS11515	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CEW87_RS11525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEW87_RS11535	COG1560	Kdo2-lipid A biosynthetic process
CEW87_RS11545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEW87_RS11565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEW87_RS11575	COG2255	four-way junction helicase activity
CEW87_RS11580	COG0632	four-way junction helicase activity
CEW87_RS11585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW87_RS11595	COG1530	ribonuclease E activity
CEW87_RS11600	COG0424	maF-like protein
CEW87_RS11605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEW87_RS11610	COG0799	negative regulation of ribosome biogenesis
CEW87_RS11615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEW87_RS11630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEW87_RS11655	COG1088	dTDP-glucose 4,6-dehydratase activity
CEW87_RS11660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEW87_RS11670	COG2089	acid synthase
CEW87_RS11675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEW87_RS11680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW87_RS11680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW87_RS11700	COG1083	cytidylyl-transferase
CEW87_RS11710	COG2192	nodulation
CEW87_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS11725	COG2226	methyltransferase
CEW87_RS11735	COG0110	maltose O-acetyltransferase activity
CEW87_RS11740	COG0110	maltose O-acetyltransferase activity
CEW87_RS11750	COG1215	transferase activity, transferring glycosyl groups
CEW87_RS11755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW87_RS11760	COG1215	transferase activity, transferring glycosyl groups
CEW87_RS11765	COG1216	Glycosyl transferase, family 2
CEW87_RS11770	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS11775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW87_RS11785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEW87_RS11795	COG2192	nodulation
CEW87_RS11805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CEW87_RS11810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEW87_RS11815	COG2233	PERMEase
CEW87_RS11835	COG0708	Exodeoxyribonuclease III
CEW87_RS11840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEW87_RS11850	COG0243	molybdopterin cofactor binding
CEW87_RS11865	COG0251	oxidation-reduction process
CEW87_RS11870	COG1238	metal cluster binding
CEW87_RS11885	COG0037	tRNA processing
CEW87_RS11890	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS11905	COG2267	carboxylic ester hydrolase activity
CEW87_RS11910	COG0625	glutathione transferase activity
CEW87_RS11920	COG0617	tRNA 3'-terminal CCA addition
CEW87_RS11935	COG0741	lytic transglycosylase activity
CEW87_RS11940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEW87_RS11945	COG5001	Diguanylate cyclase
CEW87_RS11945	COG3447	MASE1 domain protein
CEW87_RS11945	COG5002	protein histidine kinase activity
CEW87_RS11955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEW87_RS11960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEW87_RS11970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEW87_RS11975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CEW87_RS11980	COG1137	ATPase activity
CEW87_RS11985	COG2137	regulation of response to DNA damage stimulus
CEW87_RS11990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEW87_RS11995	COG1546	Belongs to the CinA family
CEW87_RS12000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEW87_RS12005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEW87_RS12010	COG3300	MHYT domain
CEW87_RS12010	COG5001	Diguanylate cyclase
CEW87_RS12035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEW87_RS12040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEW87_RS12045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEW87_RS12060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEW87_RS12065	COG4974	Belongs to the 'phage' integrase family
CEW87_RS12070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEW87_RS12075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEW87_RS12080	COG1466	dna polymerase III delta subunit
CEW87_RS12090	COG0495	leucyl-tRNA aminoacylation
CEW87_RS12100	COG0210	DNA helicase
CEW87_RS12105	COG1192	Involved in chromosome partitioning
CEW87_RS12110	COG0280	phosphate acetyltransferase
CEW87_RS12110	COG0281	malic enzyme
CEW87_RS12125	COG0668	transmembrane transport
CEW87_RS12135	COG0408	coproporphyrinogen oxidase activity
CEW87_RS12140	COG3422	double-strand break repair
CEW87_RS12145	COG0151	Belongs to the GarS family
CEW87_RS12150	COG0138	bifunctional purine biosynthesis protein purh
CEW87_RS12155	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEW87_RS12165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW87_RS12170	COG0006	proline dipeptidase activity
CEW87_RS12185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEW87_RS12190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW87_RS12195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEW87_RS12200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEW87_RS12220	COG0004	ammonium transporteR
CEW87_RS12245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEW87_RS12260	COG2353	YceI-like domain
CEW87_RS12270	COG3038	cytochrome b561
CEW87_RS12275	COG3384	dioxygenase
CEW87_RS12285	COG3437	response regulator, receiver
CEW87_RS12305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEW87_RS12320	COG0191	fructose-bisphosphate aldolase activity
CEW87_RS12325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW87_RS12335	COG3954	Phosphoribulokinase
CEW87_RS12350	COG4451	ribulose bisphosphate carboxylase, small
CEW87_RS12375	COG0469	pyruvate kinase activity
CEW87_RS12390	COG2205	protein histidine kinase activity
CEW87_RS12410	COG0126	phosphoglycerate kinase activity
CEW87_RS12420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW87_RS12425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEW87_RS12440	COG0483	inositol monophosphate 1-phosphatase activity
CEW87_RS12445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEW87_RS12455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEW87_RS12455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEW87_RS12465	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEW87_RS12470	COG0704	Plays a role in the regulation of phosphate uptake
CEW87_RS12475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEW87_RS12480	COG0303	'Molybdopterin
CEW87_RS12485	COG2833	Protein of unknown function (DUF455)
CEW87_RS12490	COG2863	cytochrome
CEW87_RS12495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEW87_RS12510	COG2226	methyltransferase
CEW87_RS12515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEW87_RS12520	COG1040	competence protein
CEW87_RS12525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEW87_RS12530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEW87_RS12540	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CEW87_RS12550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW87_RS12560	COG0588	phosphoglycerate mutase activity
CEW87_RS12570	COG0793	Belongs to the peptidase S41A family
CEW87_RS12585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW87_RS12585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW87_RS12590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEW87_RS12595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEW87_RS12615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW87_RS12620	COG4651	solute:proton antiporter activity
CEW87_RS12620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEW87_RS12630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEW87_RS12640	COG0402	S-adenosylhomocysteine deaminase activity
CEW87_RS12645	COG2815	serine threonine protein kinase
CEW87_RS12645	COG0515	serine threonine protein kinase
CEW87_RS12650	COG1950	PFAM Membrane protein of
CEW87_RS12655	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEW87_RS12660	COG1420	regulation of RNA biosynthetic process
CEW87_RS12665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEW87_RS12670	COG0497	DNA recombination
CEW87_RS12675	COG0735	belongs to the Fur family
CEW87_RS12680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEW87_RS12685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEW87_RS12690	COG0784	Response regulator, receiver
CEW87_RS12690	COG2205	protein histidine kinase activity
CEW87_RS12690	COG5002	protein histidine kinase activity
CEW87_RS12695	COG0505	Belongs to the CarA family
CEW87_RS12700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEW87_RS12705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW87_RS12715	COG1534	Rna-binding protein
CEW87_RS12720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEW87_RS12725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW87_RS12730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEW87_RS12735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEW87_RS12740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEW87_RS12745	COG0573	inorganic phosphate transmembrane transporter activity
CEW87_RS12750	COG0581	inorganic phosphate transmembrane transporter activity
CEW87_RS12765	COG0149	triose-phosphate isomerase activity
CEW87_RS12780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW87_RS12785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW87_RS12790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW87_RS12795	COG0649	NAD binding
CEW87_RS12800	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CEW87_RS12805	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW87_RS12810	COG1034	ATP synthesis coupled electron transport
CEW87_RS12815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CEW87_RS12820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW87_RS12830	COG0713	ATP synthesis coupled electron transport
CEW87_RS12845	COG1007	ATP synthesis coupled electron transport
CEW87_RS12860	COG0657	acetylesterase activity
CEW87_RS12870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW87_RS12875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW87_RS12880	COG1129	ABC transporter
CEW87_RS12880	COG0842	Transport permease protein
CEW87_RS12885	COG0842	Transport permease protein
CEW87_RS12905	COG0330	HflC and HflK could
CEW87_RS12915	COG1126	abc transporter atp-binding protein
CEW87_RS12920	COG0765	amino acid transport
CEW87_RS12940	COG2200	EAL domain
CEW87_RS12960	COG2259	Doxx family
CEW87_RS12965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_RS12990	COG2409	Drug exporters of the RND superfamily
CEW87_RS13005	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS13010	COG1522	sequence-specific DNA binding
CEW87_RS13020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEW87_RS13040	COG0564	pseudouridine synthase activity
CEW87_RS13055	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW87_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS13070	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CEW87_RS13075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEW87_RS13080	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEW87_RS13085	COG0277	FAD linked oxidase domain protein
CEW87_RS13120	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CEW87_RS13125	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS13130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEW87_RS13140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEW87_RS13150	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS13155	COG0028	Belongs to the TPP enzyme family
CEW87_RS13160	COG0440	acetolactate synthase activity
CEW87_RS13165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEW87_RS13175	COG4783	chaperone-mediated protein folding
CEW87_RS13180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEW87_RS13185	COG0066	3-isopropylmalate dehydratase activity
CEW87_RS13190	COG0473	3-isopropylmalate dehydrogenase activity
CEW87_RS13210	COG0101	tRNA pseudouridine synthase activity
CEW87_RS13215	COG0135	phosphoribosylanthranilate isomerase activity
CEW87_RS13220	COG0133	tryptophan synthase activity
CEW87_RS13225	COG0159	tryptophan synthase activity
CEW87_RS13230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEW87_RS13235	COG0285	dihydrofolate synthase activity
CEW87_RS13260	COG2239	Acts as a magnesium transporter
CEW87_RS13270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW87_RS13275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEW87_RS13280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEW87_RS13285	COG0215	cysteine-tRNA ligase activity
CEW87_RS13295	COG0484	heat shock protein binding
CEW87_RS13300	COG0443	Heat shock 70 kDa protein
CEW87_RS13305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEW87_RS13315	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEW87_RS13325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW87_RS13330	COG0287	Prephenate dehydrogenase
CEW87_RS13335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEW87_RS13345	COG0776	regulation of translation
CEW87_RS13355	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEW87_RS13395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEW87_RS13400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEW87_RS13405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEW87_RS13410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEW87_RS13415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEW87_RS13420	COG0072	phenylalanine-tRNA ligase activity
CEW87_RS13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW87_RS13425	COG0776	regulation of translation
CEW87_RS13445	COG0494	nUDIX hydrolase
CEW87_RS13450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW87_RS13455	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEW87_RS13460	COG1760	l-serine dehydratase
CEW87_RS13465	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEW87_RS13470	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CEW87_RS13490	COG0298	carbon dioxide binding
CEW87_RS13500	COG1773	rubredoxin
CEW87_RS13520	COG0375	protein maturation
CEW87_RS13530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CEW87_RS13535	COG0298	carbon dioxide binding
CEW87_RS13540	COG0409	Hydrogenase expression formation protein
CEW87_RS13545	COG0309	Hydrogenase expression formation protein (HypE)
CEW87_RS13550	COG1024	Enoyl-CoA hydratase
CEW87_RS13550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW87_RS13555	COG2204	response regulator
CEW87_RS13560	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEW87_RS13580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEW87_RS13585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEW87_RS13600	COG2951	lytic endotransglycosylase activity
CEW87_RS13615	COG0714	Associated with various cellular activities
CEW87_RS13620	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEW87_RS13625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEW87_RS13630	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEW87_RS13645	COG2850	peptidyl-arginine hydroxylation
CEW87_RS13650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW87_RS13660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEW87_RS13665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEW87_RS13680	COG0154	amidase activity
CEW87_RS13685	COG0444	Belongs to the ABC transporter superfamily
CEW87_RS13690	COG4608	Belongs to the ABC transporter superfamily
CEW87_RS13695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW87_RS13700	COG0601	transmembrane transport
CEW87_RS13705	COG0747	negative chemotaxis
CEW87_RS13730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEW87_RS13745	COG1191	sigma factor activity
CEW87_RS13750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEW87_RS13755	COG1360	Flagellar Motor Protein
CEW87_RS13770	COG0187	DNA topoisomerase II activity
CEW87_RS13790	COG1815	bacterial-type flagellum-dependent cell motility
CEW87_RS13800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEW87_RS13810	COG4787	bacterial-type flagellum-dependent cell motility
CEW87_RS13820	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEW87_RS13825	COG1706	bacterial-type flagellum-dependent cell motility
CEW87_RS13830	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEW87_RS13830	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEW87_RS13870	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEW87_RS13885	COG3144	bacterial-type flagellum assembly
CEW87_RS13910	COG0189	ligase activity
CEW87_RS13915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW87_RS13920	COG4215	(ABC) transporter
CEW87_RS13925	COG4160	amino acid transport
CEW87_RS13955	COG2814	Major facilitator Superfamily
CEW87_RS13965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEW87_RS13970	COG0471	metal ion transport
CEW87_RS13975	COG4181	ATPase activity
CEW87_RS14030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEW87_RS14080	COG4804	nuclease activity
CEW87_RS14085	COG0514	ATP-dependent DNA helicase (RecQ)
CEW87_RS14120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEW87_RS14130	COG4999	Histidine kinase
CEW87_RS14130	COG3850	Histidine kinase
CEW87_RS14130	COG3437	response regulator, receiver
CEW87_RS14130	COG2205	protein histidine kinase activity
CEW87_RS14135	COG0784	Response regulator, receiver
CEW87_RS14135	COG2205	protein histidine kinase activity
CEW87_RS14135	COG5002	protein histidine kinase activity
CEW87_RS14150	COG5001	Diguanylate cyclase
CEW87_RS14150	COG3300	MHYT domain
CEW87_RS14160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEW87_RS14165	COG0504	CTP synthase activity
CEW87_RS14170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEW87_RS14175	COG0148	phosphopyruvate hydratase activity
CEW87_RS14180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEW87_RS14190	COG0791	NLP P60 protein
CEW87_RS14200	COG0697	spore germination
CEW87_RS14225	COG2814	Major facilitator Superfamily
CEW87_RS14230	COG0583	DNA-binding transcription factor activity
CEW87_RS14250	COG0039	L-malate dehydrogenase activity
CEW87_RS14270	COG1053	succinate dehydrogenase
CEW87_RS14275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEW87_RS14280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEW87_RS14285	COG0372	Belongs to the citrate synthase family
CEW87_RS14290	COG0567	Dehydrogenase, E1 component
CEW87_RS14295	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW87_RS14300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW87_RS14305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEW87_RS14375	COG1199	ATP-dependent helicase activity
CEW87_RS14380	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEW87_RS14385	COG0303	'Molybdopterin
CEW87_RS14390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEW87_RS14395	COG0314	molybdopterin synthase activity
CEW87_RS14405	COG1388	LysM domain
CEW87_RS14405	COG0741	lytic transglycosylase activity
CEW87_RS14410	COG3706	GGDEF domain
CEW87_RS14410	COG4251	negative regulation of phosphorylation
CEW87_RS14410	COG2203	Gaf domain
CEW87_RS14410	COG5001	Diguanylate cyclase
CEW87_RS14420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW87_RS14425	COG2226	methyltransferase
CEW87_RS14430	COG0328	RNA-DNA hybrid ribonuclease activity
CEW87_RS14440	COG0517	IMP dehydrogenase activity
CEW87_RS14455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEW87_RS14480	COG1876	peptidase activity
CEW87_RS14505	COG3045	CreA protein
CEW87_RS14540	COG0840	transmembrane signaling receptor activity
CEW87_RS14550	COG2032	superoxide dismutase activity
CEW87_RS14565	COG4176	ABC-type proline glycine betaine transport system permease component
CEW87_RS14570	COG2113	Glycine betaine
CEW87_RS14575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEW87_RS14585	COG0330	HflC and HflK could
CEW87_RS14600	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW87_RS14610	COG2197	response regulator
CEW87_RS14650	COG1294	oxidase, subunit
CEW87_RS14670	COG0723	plastoquinol--plastocyanin reductase activity
CEW87_RS14690	COG0450	alkyl hydroperoxide reductase
CEW87_RS14700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW87_RS14715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW87_RS14725	COG1522	sequence-specific DNA binding
CEW87_RS14730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW87_RS14740	COG3608	succinylglutamate desuccinylase aspartoacylase
CEW87_RS14745	COG0006	proline dipeptidase activity
CEW87_RS14750	COG0006	proline dipeptidase activity
CEW87_RS14755	COG2423	ornithine cyclodeaminase activity
CEW87_RS14760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW87_RS14765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEW87_RS14775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS14780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEW87_RS14785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS14800	COG2989	Protein conserved in bacteria
CEW87_RS14815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEW87_RS14820	COG0730	response to heat
CEW87_RS14825	COG0583	DNA-binding transcription factor activity
CEW87_RS14845	COG3622	Belongs to the hyi family
CEW87_RS14850	COG0697	spore germination
CEW87_RS14860	COG4266	Belongs to the allantoicase family
CEW87_RS14885	COG1953	Uracil, thiamine, allantoin
CEW87_RS14890	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CEW87_RS14895	COG4266	Belongs to the allantoicase family
CEW87_RS14910	COG2351	hydroxyisourate hydrolase activity
CEW87_RS14925	COG0701	Predicted permease
CEW87_RS14950	COG1944	ATP diphosphatase activity
CEW87_RS14970	COG1309	transcriptional regulator
CEW87_RS14990	COG2860	membrane
CEW87_RS15040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW87_RS15050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CEW87_RS15055	COG0583	DNA-binding transcription factor activity
CEW87_RS15065	COG2217	Heavy metal translocating P-type atpase
CEW87_RS15075	COG3278	Belongs to the heme-copper respiratory oxidase family
CEW87_RS15090	COG2010	Cytochrome c
CEW87_RS15120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEW87_RS15125	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW87_RS15130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW87_RS15140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW87_RS15145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEW87_RS15160	COG2217	Heavy metal translocating P-type atpase
CEW87_RS15170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEW87_RS15185	COG2130	NADP-dependent
CEW87_RS15190	COG1979	alcohol dehydrogenase
CEW87_RS15195	COG1309	transcriptional regulator
CEW87_RS15210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS15210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEW87_RS15215	COG0347	Belongs to the P(II) protein family
CEW87_RS15220	COG2840	Smr protein MutS2
CEW87_RS15225	COG0492	ferredoxin-NADP+ reductase activity
CEW87_RS15240	COG1674	ftsk spoiiie
CEW87_RS15245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEW87_RS15250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEW87_RS15260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEW87_RS15265	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEW87_RS15270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEW87_RS15325	COG0583	DNA-binding transcription factor activity
CEW87_RS15330	COG2855	membrane
CEW87_RS15340	COG2188	Transcriptional regulator
CEW87_RS15345	COG1053	succinate dehydrogenase
CEW87_RS15360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEW87_RS15365	COG4521	taurine ABC transporter
CEW87_RS15375	COG1116	anion transmembrane transporter activity
CEW87_RS15425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEW87_RS15425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW87_RS15430	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS15435	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS15440	COG1024	Enoyl-CoA hydratase
CEW87_RS15455	COG2346	COG2346, Truncated hemoglobins
CEW87_RS15475	COG0753	catalase activity
CEW87_RS15490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS15495	COG0745	RESPONSE REGULATOR receiver
CEW87_RS15500	COG0642	Histidine kinase
CEW87_RS15515	COG4585	Histidine kinase
CEW87_RS15540	COG0167	dihydroorotate dehydrogenase activity
CEW87_RS15545	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEW87_RS15545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEW87_RS15545	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEW87_RS15545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEW87_RS15555	COG1418	mRNA catabolic process
CEW87_RS15560	COG0348	domain, Protein
CEW87_RS15565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW87_RS15585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEW87_RS15590	COG0066	3-isopropylmalate dehydratase activity
CEW87_RS15600	COG0583	DNA-binding transcription factor activity
CEW87_RS15605	COG2828	Protein conserved in bacteria
CEW87_RS15620	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CEW87_RS15625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW87_RS15645	COG1053	succinate dehydrogenase
CEW87_RS15645	COG3976	FMN-binding domain protein
CEW87_RS15645	COG0431	NADPH-dependent FMN reductase
CEW87_RS15660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW87_RS15665	COG2828	Protein conserved in bacteria
CEW87_RS15695	COG0702	epimerase
CEW87_RS15715	COG2918	glutathione biosynthetic process
CEW87_RS15730	COG2133	pyrroloquinoline quinone binding
CEW87_RS15730	COG5183	chlorophyll binding
CEW87_RS15780	COG1222	aaa ATPase
CEW87_RS15825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW87_RS15830	COG0642	Histidine kinase
CEW87_RS15855	COG5001	Diguanylate cyclase
CEW87_RS15870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEW87_RS15885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS15885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEW87_RS15895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS15900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS15910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW87_RS15915	COG2022	thiamine diphosphate biosynthetic process
CEW87_RS15925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEW87_RS15930	COG2855	membrane
CEW87_RS15940	COG1414	Transcriptional regulator
CEW87_RS15975	COG0697	spore germination
CEW87_RS15995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW87_RS16000	COG2823	Periplasmic or secreted lipoprotein
CEW87_RS16040	COG1414	Transcriptional regulator
CEW87_RS16045	COG0730	response to heat
CEW87_RS16060	COG1414	Transcriptional regulator
CEW87_RS16065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS16070	COG0242	peptide deformylase activity
CEW87_RS16080	COG0583	DNA-binding transcription factor activity
CEW87_RS16085	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS16090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW87_RS16105	COG4625	pathogenesis
CEW87_RS16105	COG3240	lipase activity
CEW87_RS16110	COG0840	transmembrane signaling receptor activity
CEW87_RS16125	COG3220	belongs to the UPF0276 family
CEW87_RS16150	COG2030	dehydratase
CEW87_RS16150	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS16175	COG0411	ABC transporter
CEW87_RS16205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW87_RS16235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CEW87_RS16240	COG0300	oxidoreductase activity
CEW87_RS16250	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS16255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CEW87_RS16285	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CEW87_RS16295	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW87_RS16295	COG0596	Alpha beta hydrolase
CEW87_RS16300	COG3384	dioxygenase
CEW87_RS16305	COG3971	2-oxopent-4-enoate hydratase activity
CEW87_RS16310	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CEW87_RS16315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW87_RS16320	COG1063	alcohol dehydrogenase
CEW87_RS16330	COG1802	Transcriptional regulator
CEW87_RS16345	COG0346	lactoylglutathione lyase activity
CEW87_RS16370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW87_RS16380	COG0633	Ferredoxin
CEW87_RS16380	COG0543	2 iron, 2 sulfur cluster binding
CEW87_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS16420	COG0583	DNA-binding transcription factor activity
CEW87_RS16455	COG0437	4 iron, 4 sulfur cluster binding
CEW87_RS16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEW87_RS16500	COG0840	transmembrane signaling receptor activity
CEW87_RS16545	COG4638	Rieske (2fe-2S)
CEW87_RS16550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CEW87_RS16565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW87_RS16605	COG1024	Enoyl-CoA hydratase
CEW87_RS16615	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS16630	COG1024	Enoyl-CoA hydratase
CEW87_RS16635	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW87_RS16645	COG0516	GMP reductase activity
CEW87_RS16665	COG0590	tRNA wobble adenosine to inosine editing
CEW87_RS16670	COG1376	ErfK ybiS ycfS ynhG family protein
CEW87_RS16695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEW87_RS16700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEW87_RS16715	COG0084	hydrolase, TatD family'
CEW87_RS16725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEW87_RS16735	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEW87_RS16745	COG2308	Evidence 4 Homologs of previously reported genes of
CEW87_RS16745	COG2307	Protein conserved in bacteria
CEW87_RS16755	COG1473	amidohydrolase
CEW87_RS16760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEW87_RS16770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEW87_RS16780	COG1067	ATP-dependent peptidase activity
CEW87_RS16795	COG0583	DNA-binding transcription factor activity
CEW87_RS16800	COG2814	Major facilitator Superfamily
CEW87_RS16820	COG0556	nucleotide-excision repair
CEW87_RS16825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEW87_RS16830	COG1530	ribonuclease E activity
CEW87_RS16840	COG0564	pseudouridine synthase activity
CEW87_RS16845	COG0546	phosphoglycolate phosphatase activity
CEW87_RS16855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEW87_RS16860	COG0424	maF-like protein
CEW87_RS16865	COG1399	metal-binding, possibly nucleic acid-binding protein
CEW87_RS16870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEW87_RS16875	COG0416	fatty acid biosynthetic process
CEW87_RS16880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW87_RS16885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEW87_RS16895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW87_RS16900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEW87_RS16910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEW87_RS16935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW87_RS16945	COG0481	GTPase activity
CEW87_RS16950	COG0681	Belongs to the peptidase S26 family
CEW87_RS16960	COG0571	ribonuclease III activity
CEW87_RS16965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEW87_RS16970	COG1381	Involved in DNA repair and RecF pathway recombination
CEW87_RS16975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEW87_RS16980	COG0736	holo-[acyl-carrier-protein] synthase activity
CEW87_RS16985	COG1472	Belongs to the glycosyl hydrolase 3 family
CEW87_RS16990	COG0322	excinuclease ABC activity
CEW87_RS17025	COG0484	heat shock protein binding
CEW87_RS17035	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEW87_RS17045	COG0850	regulation of cytokinetic process
CEW87_RS17050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEW87_RS17055	COG1393	Belongs to the ArsC family
CEW87_RS17060	COG2183	response to ionizing radiation
CEW87_RS17070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEW87_RS17070	COG1042	CoA-binding domain protein
CEW87_RS17070	COG0045	succinate-CoA ligase (ADP-forming) activity
CEW87_RS17075	COG2205	protein histidine kinase activity
CEW87_RS17075	COG2202	Pas domain
CEW87_RS17085	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CEW87_RS17090	COG0709	Synthesizes selenophosphate from selenide and ATP
CEW87_RS17100	COG4181	ATPase activity
CEW87_RS17105	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CEW87_RS17110	COG1562	ergosterol biosynthetic process
CEW87_RS17120	COG1136	(ABC) transporter
CEW87_RS17135	COG5002	protein histidine kinase activity
CEW87_RS17135	COG5001	Diguanylate cyclase
CEW87_RS17155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS17160	COG0564	pseudouridine synthase activity
CEW87_RS17170	COG0583	DNA-binding transcription factor activity
CEW87_RS17180	COG1573	uracil-dna glycosylase
CEW87_RS17210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW87_RS17220	COG2917	probably involved in intracellular septation
CEW87_RS17225	COG2350	Protein conserved in bacteria
CEW87_RS17230	COG0271	Belongs to the BolA IbaG family
CEW87_RS17235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW87_RS17240	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS17260	COG1309	transcriptional regulator
CEW87_RS17265	COG0084	hydrolase, TatD family'
CEW87_RS17270	COG1024	Enoyl-CoA hydratase
CEW87_RS17275	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS17290	COG1127	ABC transporter
CEW87_RS17295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEW87_RS17300	COG0248	Ppx GppA phosphatase
CEW87_RS17305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEW87_RS17310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW87_RS17320	COG0697	spore germination
CEW87_RS17345	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEW87_RS17350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEW87_RS17360	COG1355	regulation of microtubule-based process
CEW87_RS17365	COG3885	ferrous iron binding
CEW87_RS17365	COG2078	PFAM AMMECR1 domain protein
CEW87_RS17385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEW87_RS17390	COG2205	protein histidine kinase activity
CEW87_RS17395	COG0745	RESPONSE REGULATOR receiver
CEW87_RS17400	COG2831	hemolysin activation secretion protein
CEW87_RS17410	COG0598	Magnesium transport protein CorA
CEW87_RS17420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEW87_RS17425	COG0560	Phosphoserine phosphatase
CEW87_RS17430	COG2866	Carboxypeptidase
CEW87_RS17435	COG3022	response to hydroperoxide
CEW87_RS17440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW87_RS17450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEW87_RS17455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW87_RS17460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW87_RS17465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEW87_RS17470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW87_RS17490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEW87_RS17495	COG0575	Belongs to the CDS family
CEW87_RS17500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEW87_RS17505	COG0233	cytoplasmic translational termination
CEW87_RS17510	COG0528	UMP kinase activity
CEW87_RS17515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEW87_RS17520	COG0052	Belongs to the universal ribosomal protein uS2 family
CEW87_RS17530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEW87_RS17535	COG2862	Uncharacterized protein family, UPF0114
CEW87_RS17555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEW87_RS17565	COG1196	nuclear chromosome segregation
CEW87_RS17570	COG0436	Aminotransferase
CEW87_RS17575	COG2171	N-acyltransferase activity
CEW87_RS17585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEW87_RS17595	COG0784	Response regulator, receiver
CEW87_RS17605	COG0633	Ferredoxin
CEW87_RS17610	COG0443	Heat shock 70 kDa protein
CEW87_RS17615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEW87_RS17625	COG0822	iron-sulfur transferase activity
CEW87_RS17630	COG1104	cysteine desulfurase activity
CEW87_RS17635	COG1104	cysteine desulfurase activity
CEW87_RS17645	COG1045	serine acetyltransferase
CEW87_RS17655	COG0483	inositol monophosphate 1-phosphatase activity
CEW87_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS17730	COG2207	Transcriptional regulator
CEW87_RS17770	COG3344	reverse transcriptase
CEW87_RS17775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEW87_RS17775	COG0519	Catalyzes the synthesis of GMP from XMP
CEW87_RS17790	COG2914	Belongs to the UPF0125 (RnfH) family
CEW87_RS17800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEW87_RS17805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEW87_RS17810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW87_RS17815	COG0601	transmembrane transport
CEW87_RS17825	COG3781	membrane
CEW87_RS17835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW87_RS17840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW87_RS17845	COG0509	glycine decarboxylation via glycine cleavage system
CEW87_RS17850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEW87_RS17850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEW87_RS17865	COG1215	transferase activity, transferring glycosyl groups
CEW87_RS17875	COG0583	DNA-binding transcription factor activity
CEW87_RS17885	COG1858	cytochrome C peroxidase
CEW87_RS17895	COG0386	Belongs to the glutathione peroxidase family
CEW87_RS17905	COG0488	(ABC) transporter
CEW87_RS17910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEW87_RS17925	COG0243	molybdopterin cofactor binding
CEW87_RS17970	COG1136	(ABC) transporter
CEW87_RS17980	COG1032	radical SAM domain protein
CEW87_RS18000	COG0537	adenosine 5'-monophosphoramidase activity
CEW87_RS18025	COG1196	nuclear chromosome segregation
CEW87_RS18045	COG2814	Major facilitator Superfamily
CEW87_RS18085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS18090	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS18095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW87_RS18125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW87_RS18130	COG0765	amino acid transport
CEW87_RS18135	COG0765	amino acid transport
CEW87_RS18170	COG1280	lysine exporter protein (LysE YggA)
CEW87_RS18185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEW87_RS18190	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS18260	COG1794	racemase activity, acting on amino acids and derivatives
CEW87_RS18270	COG1522	sequence-specific DNA binding
CEW87_RS18285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEW87_RS18290	COG1309	transcriptional regulator
CEW87_RS18295	COG1744	ABC transporter substrate-binding protein PnrA-like
CEW87_RS18300	COG3845	ABC transporter
CEW87_RS18310	COG1079	Belongs to the binding-protein-dependent transport system permease family
CEW87_RS18315	COG0402	S-adenosylhomocysteine deaminase activity
CEW87_RS18320	COG1448	Aminotransferase
CEW87_RS18365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEW87_RS18420	COG1490	D-aminoacyl-tRNA deacylase activity
CEW87_RS18425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEW87_RS18430	COG3842	ATPase activity
CEW87_RS18435	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW87_RS18440	COG1177	transmembrane transport
CEW87_RS18445	COG1115	amino acid carrier protein
CEW87_RS18455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW87_RS18455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEW87_RS18470	COG5002	protein histidine kinase activity
CEW87_RS18470	COG5001	Diguanylate cyclase
CEW87_RS18470	COG3447	MASE1 domain protein
CEW87_RS18475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW87_RS18490	COG3706	GGDEF domain
CEW87_RS18500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEW87_RS18535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW87_RS18540	COG0587	DNA-directed DNA polymerase activity
CEW87_RS18550	COG0583	DNA-binding transcription factor activity
CEW87_RS18555	COG1063	alcohol dehydrogenase
CEW87_RS18580	COG0436	Aminotransferase
CEW87_RS18590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_RS18595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEW87_RS18600	COG0840	transmembrane signaling receptor activity
CEW87_RS18615	COG0791	NLP P60 protein
CEW87_RS18625	COG1840	ABC-type Fe3 transport system, periplasmic component
CEW87_RS18630	COG1178	ABC-type Fe3 transport system permease component
CEW87_RS18635	COG3842	ATPase activity
CEW87_RS18640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEW87_RS18645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEW87_RS18650	COG0167	dihydroorotate dehydrogenase activity
CEW87_RS18655	COG4657	Part of a membrane complex involved in electron transport
CEW87_RS18660	COG2878	Part of a membrane complex involved in electron transport
CEW87_RS18675	COG4659	FMN binding
CEW87_RS18685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEW87_RS18705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW87_RS18720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW87_RS18720	COG0426	domain, Protein
CEW87_RS18725	COG1846	Transcriptional regulator
CEW87_RS18775	COG0326	Molecular chaperone. Has ATPase activity
CEW87_RS18790	COG1511	domain protein
CEW87_RS18790	COG3264	Mechanosensitive ion channel
CEW87_RS18805	COG0596	Alpha beta hydrolase
CEW87_RS18820	COG1230	cation diffusion facilitator family transporter
CEW87_RS18830	COG3135	benzoate transporter
CEW87_RS18840	COG3259	Nickel-dependent hydrogenase
CEW87_RS18845	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
CEW87_RS18850	COG3383	formate dehydrogenase (NAD+) activity
CEW87_RS18855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW87_RS18860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW87_RS18870	COG2205	protein histidine kinase activity
CEW87_RS18870	COG4999	Histidine kinase
CEW87_RS18870	COG3437	response regulator, receiver
CEW87_RS18870	COG3850	Histidine kinase
CEW87_RS18890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW87_RS18895	COG0824	Thioesterase
CEW87_RS18915	COG4771	TonB-dependent receptor
CEW87_RS18925	COG3901	Regulator of nitric oxide reductase transcription
CEW87_RS18925	COG0348	domain, Protein
CEW87_RS18950	COG1999	signal sequence binding
CEW87_RS18960	COG0047	phosphoribosylformylglycinamidine synthase activity
CEW87_RS18960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEW87_RS18965	COG0671	phosphoesterase, PA-phosphatase related
CEW87_RS18975	COG0463	Glycosyl transferase, family 2
CEW87_RS18995	COG0741	lytic transglycosylase activity
CEW87_RS18995	COG0739	heme binding
CEW87_RS18995	COG1196	nuclear chromosome segregation
CEW87_RS19005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEW87_RS19015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW87_RS19020	COG2267	carboxylic ester hydrolase activity
CEW87_RS19025	COG2133	pyrroloquinoline quinone binding
CEW87_RS19035	COG0625	glutathione transferase activity
CEW87_RS19120	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS19145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEW87_RS19150	COG0006	proline dipeptidase activity
CEW87_RS19160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW87_RS19165	COG5002	protein histidine kinase activity
CEW87_RS19165	COG2176	DNA-directed DNA polymerase activity
CEW87_RS19175	COG5002	protein histidine kinase activity
CEW87_RS19185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW87_RS19200	COG2010	Cytochrome c
CEW87_RS19215	COG2814	Major facilitator Superfamily
CEW87_RS19255	COG2223	nitrite transmembrane transporter activity
CEW87_RS19265	COG0535	radical SAM domain protein
CEW87_RS19270	COG2116	formate transmembrane transporter activity
CEW87_RS19275	COG0515	serine threonine protein kinase
CEW87_RS19280	COG1279	arginine transmembrane transporter activity
CEW87_RS19290	COG0697	spore germination
CEW87_RS19330	COG1522	sequence-specific DNA binding
CEW87_RS19350	COG1648	precorrin-2 dehydrogenase activity
CEW87_RS19350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEW87_RS19355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW87_RS19360	COG2226	methyltransferase
CEW87_RS19385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEW87_RS19390	COG1185	polyribonucleotide nucleotidyltransferase activity
CEW87_RS19395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEW87_RS19400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEW87_RS19405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEW87_RS19410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEW87_RS19415	COG0195	Participates in both transcription termination and antitermination
CEW87_RS19415	COG2251	uridine kinase activity
CEW87_RS19420	COG0779	Required for maturation of 30S ribosomal subunits
CEW87_RS19430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEW87_RS19435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEW87_RS19440	COG0180	Tryptophanyl-tRNA synthetase
CEW87_RS19445	COG1994	Peptidase M50
CEW87_RS19450	COG0009	L-threonylcarbamoyladenylate synthase
CEW87_RS19455	COG0613	PHP domain protein
CEW87_RS19470	COG0542	response to heat
CEW87_RS19485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_RS19490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEW87_RS19505	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEW87_RS19515	COG2081	HI0933 family
CEW87_RS19550	COG0826	peptidase U32
CEW87_RS19555	COG2900	Belongs to the SlyX family
CEW87_RS19580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEW87_RS19585	COG1278	Cold shock
CEW87_RS19590	COG0513	Belongs to the DEAD box helicase family
CEW87_RS19615	COG4681	YaeQ
CEW87_RS19630	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEW87_RS19640	COG0302	gtp cyclohydrolase
CEW87_RS19650	COG0306	phosphate transporter
CEW87_RS19660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEW87_RS19665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEW87_RS19670	COG2233	PERMEase
CEW87_RS19685	COG4206	TonB-dependent receptor
CEW87_RS19690	COG4206	TonB-dependent receptor
CEW87_RS19695	COG2204	response regulator
CEW87_RS19715	COG2358	TRAP transporter, solute receptor (TAXI family
CEW87_RS19720	COG0579	oxidoreductase
CEW87_RS19745	COG3647	Membrane
CEW87_RS19750	COG0348	domain, Protein
CEW87_RS19755	COG1959	2 iron, 2 sulfur cluster binding
CEW87_RS19760	COG0516	GMP reductase activity
CEW87_RS19760	COG0517	IMP dehydrogenase activity
CEW87_RS19765	COG2354	Protein conserved in bacteria
CEW87_RS19785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW87_RS19795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS19825	COG1363	Peptidase, m42
CEW87_RS19830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEW87_RS19830	COG0189	ligase activity
CEW87_RS19870	COG1741	Belongs to the pirin family
CEW87_RS19885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW87_RS19890	COG1254	Belongs to the acylphosphatase family
CEW87_RS19895	COG0443	Heat shock 70 kDa protein
CEW87_RS19900	COG1077	Cell shape determining protein MreB Mrl
CEW87_RS19910	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEW87_RS19930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS19950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW87_RS19955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEW87_RS19965	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW87_RS19975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW87_RS19975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW87_RS19980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW87_RS19990	COG1132	(ABC) transporter
CEW87_RS20005	COG2814	Major facilitator Superfamily
CEW87_RS20015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW87_RS20020	COG1272	protein, Hemolysin III
CEW87_RS20030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW87_RS20035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW87_RS20040	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS20055	COG0183	Belongs to the thiolase family
CEW87_RS20060	COG1024	Enoyl-CoA hydratase
CEW87_RS20065	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS20105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW87_RS20120	COG0583	DNA-binding transcription factor activity
CEW87_RS20130	COG0667	Aldo Keto reductase
CEW87_RS20160	COG2159	amidohydrolase
CEW87_RS20205	COG3706	GGDEF domain
CEW87_RS20245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEW87_RS20250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEW87_RS20255	COG0740	serine-type endopeptidase activity
CEW87_RS20260	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEW87_RS20265	COG2766	serine protein kinase
CEW87_RS20270	COG2718	Belongs to the UPF0229 family
CEW87_RS20275	COG2719	SpoVR family
CEW87_RS20280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEW87_RS20280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEW87_RS20290	COG0697	spore germination
CEW87_RS20300	COG1595	DNA-templated transcription, initiation
CEW87_RS20310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEW87_RS20340	COG0438	transferase activity, transferring glycosyl groups
CEW87_RS20355	COG1183	phosphatidylcholine synthase activity
CEW87_RS20370	COG3360	Dodecin
CEW87_RS20405	COG1136	(ABC) transporter
CEW87_RS20415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW87_RS20425	COG0009	L-threonylcarbamoyladenylate synthase
CEW87_RS20430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEW87_RS20435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEW87_RS20440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW87_RS20450	COG4566	intracellular signal transduction
CEW87_RS20465	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEW87_RS20470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW87_RS20475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW87_RS20505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEW87_RS20510	COG0802	atpase or kinase
CEW87_RS20515	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEW87_RS20520	COG0196	riboflavin kinase activity
CEW87_RS20525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEW87_RS20530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEW87_RS20535	COG1047	Peptidyl-prolyl cis-trans
CEW87_RS20540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEW87_RS20550	COG1722	exodeoxyribonuclease VII activity
CEW87_RS20555	COG0142	geranyltranstransferase activity
CEW87_RS20560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEW87_RS20565	COG1469	GTP cyclohydrolase I activity
CEW87_RS20570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEW87_RS20580	COG0022	dehydrogenase e1 component
CEW87_RS20585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEW87_RS20605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEW87_RS20610	COG3012	SEC-C Motif Domain Protein
CEW87_RS20645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEW87_RS20650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEW87_RS20655	COG0254	rRNA binding
CEW87_RS20665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEW87_RS20670	COG0501	Belongs to the peptidase M48B family
CEW87_RS20690	COG2308	Evidence 4 Homologs of previously reported genes of
CEW87_RS20695	COG0183	Belongs to the thiolase family
CEW87_RS20725	COG1666	GTP binding
CEW87_RS20730	COG3123	guanosine phosphorylase activity
CEW87_RS20740	COG0137	argininosuccinate synthase activity
CEW87_RS20745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEW87_RS20750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW87_RS20760	COG0268	Binds directly to 16S ribosomal RNA
CEW87_RS20770	COG1881	PFAM PEBP family protein
CEW87_RS20785	COG0563	adenylate kinase activity
CEW87_RS20790	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEW87_RS20795	COG2835	tetraacyldisaccharide 4'-kinase activity
CEW87_RS20800	COG1663	tetraacyldisaccharide 4'-kinase activity
CEW87_RS20810	COG0811	peptide transport
CEW87_RS20815	COG1570	exodeoxyribonuclease VII activity
CEW87_RS20820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEW87_RS20825	COG0564	pseudouridine synthase activity
CEW87_RS20835	COG2198	Histidine kinase
CEW87_RS20835	COG0643	Histidine kinase
CEW87_RS20835	COG0784	Response regulator, receiver
CEW87_RS20840	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEW87_RS20845	COG0745	RESPONSE REGULATOR receiver
CEW87_RS20850	COG0784	Response regulator, receiver
CEW87_RS20850	COG0835	chemotaxis
CEW87_RS20855	COG0835	chemotaxis
CEW87_RS20855	COG0784	Response regulator, receiver
CEW87_RS20860	COG0840	transmembrane signaling receptor activity
CEW87_RS20865	COG2201	protein-glutamate methylesterase activity
CEW87_RS20880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEW87_RS20925	COG3845	ABC transporter
CEW87_RS20930	COG4603	Belongs to the binding-protein-dependent transport system permease family
CEW87_RS20935	COG1079	Belongs to the binding-protein-dependent transport system permease family
CEW87_RS20950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEW87_RS20985	COG2226	methyltransferase
CEW87_RS20990	COG3754	Rhamnan synthesis protein F
CEW87_RS21010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEW87_RS21030	COG2257	FlhB HrpN YscU SpaS Family
CEW87_RS21035	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEW87_RS21040	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEW87_RS21045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CEW87_RS21055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW87_RS21065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEW87_RS21070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEW87_RS21085	COG3181	Tripartite tricarboxylate transporter family receptor
CEW87_RS21090	COG2721	sulfolactate sulfo-lyase activity
CEW87_RS21095	COG2721	sulfolactate sulfo-lyase activity
CEW87_RS21100	COG2188	Transcriptional regulator
CEW87_RS21105	COG2188	Transcriptional regulator
CEW87_RS21110	COG2855	membrane
CEW87_RS21120	COG1609	Transcriptional regulator
CEW87_RS21130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW87_RS21135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS21135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEW87_RS21140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS21140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEW87_RS21145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEW87_RS21150	COG1028	Short-chain dehydrogenase reductase Sdr
CEW87_RS21160	COG1677	Flagellar hook-basal body complex protein FliE
CEW87_RS21190	COG1157	protein secretion by the type III secretion system
CEW87_RS21200	COG0402	S-adenosylhomocysteine deaminase activity
CEW87_RS21215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CEW87_RS21215	COG0662	Cupin 2, conserved barrel domain protein
CEW87_RS21220	COG0175	sulfate reduction
CEW87_RS21235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEW87_RS21255	COG0583	DNA-binding transcription factor activity
CEW87_RS21270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEW87_RS21280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEW87_RS21305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEW87_RS21310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEW87_RS21310	COG0517	IMP dehydrogenase activity
CEW87_RS21315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEW87_RS21325	COG0110	maltose O-acetyltransferase activity
CEW87_RS21365	COG1091	dTDP-4-dehydrorhamnose reductase activity
CEW87_RS21390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW87_RS21395	COG3852	Histidine kinase
CEW87_RS21430	COG0471	metal ion transport
CEW87_RS21430	COG3273	potassium ion transport
CEW87_RS21460	COG2204	response regulator
CEW87_RS21485	COG3383	formate dehydrogenase (NAD+) activity
CEW87_RS21550	COG2259	Doxx family
CEW87_RS21560	COG3220	belongs to the UPF0276 family
CEW87_RS21585	COG0793	Belongs to the peptidase S41A family
CEW87_RS21605	COG0527	aspartate kinase activity
CEW87_RS21620	COG0720	synthase
CEW87_RS21630	COG3264	Mechanosensitive ion channel
CEW87_RS21630	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEW87_RS21635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW87_RS21640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW87_RS21640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEW87_RS21650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEW87_RS21660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEW87_RS21665	COG1238	metal cluster binding
CEW87_RS21675	COG3706	GGDEF domain
CEW87_RS21690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEW87_RS21720	COG0028	Belongs to the TPP enzyme family
CEW87_RS21725	COG0440	acetolactate synthase activity
CEW87_RS21730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEW87_RS21755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEW87_RS21760	COG1183	phosphatidylcholine synthase activity
CEW87_RS21775	COG0642	Histidine kinase
CEW87_RS21785	COG3642	lipopolysaccharide core region biosynthetic process
CEW87_RS21810	COG1858	cytochrome C peroxidase
CEW87_RS21820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW87_RS21825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW87_RS21840	COG1295	ribonuclease BN
CEW87_RS21850	COG0228	four-way junction DNA binding
CEW87_RS21855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEW87_RS21860	COG0336	Belongs to the RNA methyltransferase TrmD family
CEW87_RS21865	COG0335	large ribosomal subunit rRNA binding
CEW87_RS21875	COG0795	lipopolysaccharide-transporting ATPase activity
CEW87_RS21880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEW87_RS21895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW87_RS21905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW87_RS21910	COG0583	DNA-binding transcription factor activity
CEW87_RS21915	COG0525	valine-tRNA ligase activity
CEW87_RS21920	COG0425	Belongs to the sulfur carrier protein TusA family
CEW87_RS21930	COG0315	cyclic pyranopterin monophosphate synthase activity
CEW87_RS21960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEW87_RS21985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEW87_RS22005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW87_RS22010	COG2414	aldehyde ferredoxin oxidoreductase
CEW87_RS22020	COG3284	Transcriptional regulator
CEW87_RS22040	COG3038	cytochrome b561
CEW87_RS22055	COG1012	belongs to the aldehyde dehydrogenase family
CEW87_RS22060	COG3284	Transcriptional regulator
CEW87_RS22080	COG4191	Histidine kinase
CEW87_RS22080	COG0784	Response regulator, receiver
CEW87_RS22085	COG0318	PFAM AMP-dependent synthetase and ligase
CEW87_RS22090	COG1960	acyl-CoA dehydrogenase activity
CEW87_RS22100	COG0659	secondary active sulfate transmembrane transporter activity
CEW87_RS22110	COG1054	Belongs to the UPF0176 family
CEW87_RS22120	COG4172	Belongs to the ABC transporter superfamily
CEW87_RS22125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW87_RS22130	COG0601	transmembrane transport
CEW87_RS22135	COG0747	negative chemotaxis
CEW87_RS22145	COG0583	DNA-binding transcription factor activity
CEW87_RS22165	COG3264	Mechanosensitive ion channel
CEW87_RS22165	COG1511	domain protein
CEW87_RS22205	COG0732	type I restriction modification DNA specificity domain
CEW87_RS22255	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase