locus-tag	class	description
dqs_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
dqs_RS00035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
dqs_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS00115	COG0583	DNA-binding transcription factor activity
dqs_RS00120	COG0564	pseudouridine synthase activity
dqs_RS00145	COG0693	protein deglycase activity
dqs_RS00170	COG3608	succinylglutamate desuccinylase aspartoacylase
dqs_RS00170	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
dqs_RS00180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS00185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_RS00190	COG1216	Glycosyl transferase, family 2
dqs_RS00200	COG1253	flavin adenine dinucleotide binding
dqs_RS00205	COG0583	DNA-binding transcription factor activity
dqs_RS00210	COG0477	Major facilitator Superfamily
dqs_RS00250	COG1944	ATP diphosphatase activity
dqs_RS00255	COG1917	Cupin 2, conserved barrel domain protein
dqs_RS00255	COG4977	sequence-specific DNA binding
dqs_RS00270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
dqs_RS00275	COG1984	allophanate hydrolase subunit 2
dqs_RS00280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
dqs_RS00285	COG0596	Alpha beta hydrolase
dqs_RS00290	COG4676	Protein conserved in bacteria
dqs_RS00295	COG4676	Protein conserved in bacteria
dqs_RS00300	COG5445	Predicted secreted protein (DUF2300)
dqs_RS00330	COG1136	(ABC) transporter
dqs_RS00335	COG0577	efflux transmembrane transporter activity
dqs_RS00350	COG2373	Large extracellular alpha-helical protein
dqs_RS00360	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
dqs_RS00375	COG0628	permease
dqs_RS00385	COG1024	Enoyl-CoA hydratase
dqs_RS00415	COG4191	Histidine kinase
dqs_RS00425	COG2304	oxidoreductase activity
dqs_RS00430	COG1595	DNA-templated transcription, initiation
dqs_RS00450	COG1690	Belongs to the RtcB family
dqs_RS00455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
dqs_RS00465	COG2974	May be involved in recombination
dqs_RS00475	COG1187	pseudouridine synthase activity
dqs_RS00485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
dqs_RS00495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
dqs_RS00505	COG3909	cytochrome
dqs_RS00510	COG0840	transmembrane signaling receptor activity
dqs_RS00515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS00520	COG4206	TonB-dependent receptor
dqs_RS00530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
dqs_RS00530	COG0551	DNA topoisomerase type I activity
dqs_RS00535	COG2922	Belongs to the Smg family
dqs_RS00540	COG0758	DNA mediated transformation
dqs_RS00550	COG0242	peptide deformylase activity
dqs_RS00555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
dqs_RS00565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_RS00570	COG1305	Transglutaminase-like
dqs_RS00600	COG1490	D-aminoacyl-tRNA deacylase activity
dqs_RS00605	COG1741	Belongs to the pirin family
dqs_RS00615	COG0583	DNA-binding transcription factor activity
dqs_RS00620	COG0625	glutathione transferase activity
dqs_RS00630	COG2030	dehydratase
dqs_RS00635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
dqs_RS00665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
dqs_RS00695	COG0840	transmembrane signaling receptor activity
dqs_RS00700	COG0840	transmembrane signaling receptor activity
dqs_RS00705	COG1942	4-Oxalocrotonate Tautomerase
dqs_RS00710	COG0583	DNA-binding transcription factor activity
dqs_RS00720	COG3706	GGDEF domain
dqs_RS00755	COG0445	tRNA wobble uridine modification
dqs_RS00760	COG0357	Ribosomal RNA small subunit methyltransferase G
dqs_RS00765	COG1192	Involved in chromosome partitioning
dqs_RS00780	COG1475	DNA binding
dqs_RS00790	COG0477	Major facilitator Superfamily
dqs_RS00795	COG0418	dihydroorotase activity
dqs_RS00805	COG0640	Transcriptional regulator
dqs_RS00815	COG0356	it plays a direct role in the translocation of protons across the membrane
dqs_RS00825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
dqs_RS00830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
dqs_RS00835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
dqs_RS00840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
dqs_RS00845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
dqs_RS00850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
dqs_RS00860	COG2226	methyltransferase
dqs_RS00870	COG0745	RESPONSE REGULATOR receiver
dqs_RS00890	COG0121	glutamine amidotransferase
dqs_RS00900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
dqs_RS00910	COG0154	amidase activity
dqs_RS00915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
dqs_RS00920	COG1077	Cell shape determining protein MreB Mrl
dqs_RS00935	COG0768	penicillin binding
dqs_RS00940	COG0772	Belongs to the SEDS family
dqs_RS00950	COG1686	Belongs to the peptidase S11 family
dqs_RS00960	COG2921	Belongs to the UPF0250 family
dqs_RS00965	COG0321	lipoyl(octanoyl) transferase activity
dqs_RS00970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
dqs_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS01035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_RS01065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
dqs_RS01065	COG0512	Glutamine amidotransferase of anthranilate synthase
dqs_RS01075	COG0419	ATPase involved in DNA repair
dqs_RS01100	COG1473	amidohydrolase
dqs_RS01105	COG2207	Transcriptional regulator
dqs_RS01135	COG1522	sequence-specific DNA binding
dqs_RS01160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_RS01170	COG0601	transmembrane transport
dqs_RS01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
dqs_RS01255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
dqs_RS01260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
dqs_RS01275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_RS01300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_RS01310	COG2193	ferroxidase activity
dqs_RS01385	COG0642	Histidine kinase
dqs_RS01435	COG1595	DNA-templated transcription, initiation
dqs_RS01475	COG1360	Flagellar Motor Protein
dqs_RS01495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_RS01515	COG1131	(ABC) transporter
dqs_RS01530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
dqs_RS01550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_RS01560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
dqs_RS01570	COG1024	Enoyl-CoA hydratase
dqs_RS01575	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS01580	COG2050	protein possibly involved in aromatic compounds catabolism
dqs_RS01590	COG3396	Phenylacetate-CoA oxygenase
dqs_RS01595	COG3460	Phenylacetate-CoA oxygenase
dqs_RS01600	COG3396	Phenylacetate-CoA oxygenase
dqs_RS01605	COG2151	metal-sulfur cluster biosynthetic enzyme
dqs_RS01610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
dqs_RS01620	COG0183	Belongs to the thiolase family
dqs_RS01650	COG0513	Belongs to the DEAD box helicase family
dqs_RS01655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
dqs_RS01660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
dqs_RS01675	COG4232	protein-disulfide reductase activity
dqs_RS01680	COG1324	tolerance protein
dqs_RS01685	COG2070	2-Nitropropane dioxygenase
dqs_RS01705	COG1309	transcriptional regulator
dqs_RS01720	COG0583	DNA-binding transcription factor activity
dqs_RS01745	COG5001	Diguanylate cyclase
dqs_RS01745	COG1716	ATPase activity
dqs_RS01750	COG3706	GGDEF domain
dqs_RS01760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
dqs_RS01780	COG1192	Involved in chromosome partitioning
dqs_RS01795	COG0025	NhaP-type Na H and K H
dqs_RS01835	COG1131	(ABC) transporter
dqs_RS01840	COG0625	glutathione transferase activity
dqs_RS01865	COG1045	serine acetyltransferase
dqs_RS01875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_RS01880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
dqs_RS01885	COG2119	membrane
dqs_RS01895	COG3154	lipid carrier protein
dqs_RS01900	COG0826	peptidase U32
dqs_RS01905	COG0826	peptidase U32
dqs_RS01910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_RS01915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_RS01920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
dqs_RS01935	COG0018	arginyl-trna synthetase
dqs_RS01945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
dqs_RS01950	COG0300	oxidoreductase activity
dqs_RS01975	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_RS01995	COG0183	Belongs to the thiolase family
dqs_RS02000	COG1960	acyl-CoA dehydrogenase activity
dqs_RS02015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_RS02020	COG1660	Displays ATPase and GTPase activities
dqs_RS02035	COG2201	protein-glutamate methylesterase activity
dqs_RS02045	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
dqs_RS02050	COG0835	chemotaxis
dqs_RS02055	COG0840	transmembrane signaling receptor activity
dqs_RS02060	COG0643	Histidine kinase
dqs_RS02060	COG2198	Histidine kinase
dqs_RS02075	COG0745	RESPONSE REGULATOR receiver
dqs_RS02090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
dqs_RS02095	COG0602	queuosine metabolic process
dqs_RS02105	COG2885	chlorophyll binding
dqs_RS02110	COG0823	Involved in the tonB-independent uptake of proteins
dqs_RS02120	COG0848	biopolymer transport protein
dqs_RS02125	COG0811	peptide transport
dqs_RS02130	COG0824	Thioesterase
dqs_RS02140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
dqs_RS02145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
dqs_RS02155	COG5001	Diguanylate cyclase
dqs_RS02155	COG3300	MHYT domain
dqs_RS02160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
dqs_RS02165	COG2895	sulfate adenylyltransferase (ATP) activity
dqs_RS02170	COG0175	sulfate reduction
dqs_RS02175	COG0175	sulfate reduction
dqs_RS02190	COG0730	response to heat
dqs_RS02195	COG0583	DNA-binding transcription factor activity
dqs_RS02220	COG1126	abc transporter atp-binding protein
dqs_RS02225	COG0765	amino acid transport
dqs_RS02230	COG0765	amino acid transport
dqs_RS02235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_RS02245	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_RS02245	COG1793	dna ligase
dqs_RS02250	COG1201	RNA secondary structure unwinding
dqs_RS02265	COG4191	Histidine kinase
dqs_RS02275	COG5001	Diguanylate cyclase
dqs_RS02285	COG0492	ferredoxin-NADP+ reductase activity
dqs_RS02290	COG5265	(ABC) transporter
dqs_RS02300	COG0523	cobalamin synthesis protein
dqs_RS02310	COG0745	RESPONSE REGULATOR receiver
dqs_RS02315	COG5002	protein histidine kinase activity
dqs_RS02320	COG0004	ammonium transporteR
dqs_RS02340	COG1960	acyl-CoA dehydrogenase activity
dqs_RS02350	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS02350	COG1024	Enoyl-CoA hydratase
dqs_RS02360	COG2067	long-chain fatty acid transport protein
dqs_RS02365	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS02365	COG1024	Enoyl-CoA hydratase
dqs_RS02370	COG0183	Belongs to the thiolase family
dqs_RS02375	COG1024	Enoyl-CoA hydratase
dqs_RS02400	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
dqs_RS02410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
dqs_RS02415	COG3161	chorismate lyase activity
dqs_RS02420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
dqs_RS02430	COG0251	oxidation-reduction process
dqs_RS02435	COG1238	metal cluster binding
dqs_RS02450	COG0037	tRNA processing
dqs_RS02475	COG0625	glutathione transferase activity
dqs_RS02485	COG0617	tRNA 3'-terminal CCA addition
dqs_RS02500	COG0741	lytic transglycosylase activity
dqs_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
dqs_RS02520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
dqs_RS02525	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
dqs_RS02535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
dqs_RS02540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
dqs_RS02550	COG2137	regulation of response to DNA damage stimulus
dqs_RS02555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
dqs_RS02560	COG1546	Belongs to the CinA family
dqs_RS02565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
dqs_RS02570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
dqs_RS02575	COG2914	Belongs to the UPF0125 (RnfH) family
dqs_RS02580	COG4660	Part of a membrane complex involved in electron transport
dqs_RS02595	COG4656	Part of a membrane complex involved in electron transport
dqs_RS02600	COG2878	Part of a membrane complex involved in electron transport
dqs_RS02605	COG4657	Part of a membrane complex involved in electron transport
dqs_RS02630	COG2032	superoxide dismutase activity
dqs_RS02640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS02650	COG0426	domain, Protein
dqs_RS02655	COG0633	Ferredoxin
dqs_RS02685	COG3647	Membrane
dqs_RS02710	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
dqs_RS02730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS02745	COG0840	transmembrane signaling receptor activity
dqs_RS03045	COG4383	Mu-like prophage protein gp29
dqs_RS03050	COG2369	cell adhesion
dqs_RS03160	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
dqs_RS03165	COG0393	Putative heavy-metal-binding
dqs_RS03175	COG0217	transcriptional regulatory protein
dqs_RS03185	COG0433	COG0433 Predicted ATPase
dqs_RS03190	COG0583	DNA-binding transcription factor activity
dqs_RS03195	COG2814	Major facilitator Superfamily
dqs_RS03200	COG0697	spore germination
dqs_RS03205	COG0840	transmembrane signaling receptor activity
dqs_RS03210	COG2814	Major facilitator Superfamily
dqs_RS03215	COG2814	Major facilitator Superfamily
dqs_RS03225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
dqs_RS03230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
dqs_RS03235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
dqs_RS03245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
dqs_RS03255	COG1560	Kdo2-lipid A biosynthetic process
dqs_RS03265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
dqs_RS03275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
dqs_RS03285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
dqs_RS03300	COG2255	four-way junction helicase activity
dqs_RS03305	COG0632	four-way junction helicase activity
dqs_RS03330	COG4774	siderophore transport
dqs_RS03335	COG3128	pkhd-type hydroxylase
dqs_RS03350	COG0577	efflux transmembrane transporter activity
dqs_RS03350	COG1136	(ABC) transporter
dqs_RS03355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_RS03400	COG5001	Diguanylate cyclase
dqs_RS03420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
dqs_RS03425	COG3132	Protein of unknown function, DUF480
dqs_RS03445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
dqs_RS03450	COG0129	dihydroxy-acid dehydratase activity
dqs_RS03460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
dqs_RS03480	COG0247	lactate metabolic process
dqs_RS03500	COG1121	(ABC) transporter
dqs_RS03505	COG0735	belongs to the Fur family
dqs_RS03515	COG2274	protein secretion by the type I secretion system
dqs_RS03520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_RS03525	COG2197	response regulator
dqs_RS03545	COG5001	Diguanylate cyclase
dqs_RS03545	COG2203	Gaf domain
dqs_RS03545	COG3706	GGDEF domain
dqs_RS03545	COG4251	negative regulation of phosphorylation
dqs_RS03555	COG1538	Outer membrane efflux protein
dqs_RS03585	COG1132	(ABC) transporter
dqs_RS03590	COG1451	nucleotide metabolic process
dqs_RS03600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
dqs_RS03605	COG2267	carboxylic ester hydrolase activity
dqs_RS03610	COG2453	phosphatase
dqs_RS03610	COG0671	phosphoesterase, PA-phosphatase related
dqs_RS03620	COG0204	Acyl-transferase
dqs_RS03625	COG4589	Belongs to the CDS family
dqs_RS03630	COG3005	denitrification pathway
dqs_RS03635	COG3043	anaerobic respiration
dqs_RS03640	COG0243	molybdopterin cofactor binding
dqs_RS03650	COG4459	periplasmic nitrate reductase
dqs_RS03680	COG0583	DNA-binding transcription factor activity
dqs_RS03685	COG1024	Enoyl-CoA hydratase
dqs_RS03690	COG3162	membrane
dqs_RS03695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_RS03700	COG1253	flavin adenine dinucleotide binding
dqs_RS03705	COG1802	Transcriptional regulator
dqs_RS03710	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_RS03710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_RS03715	COG1703	isobutyryl-CoA mutase activity
dqs_RS03720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
dqs_RS03725	COG4770	biotin carboxylase activity
dqs_RS03740	COG2321	neutral zinc metallopeptidase
dqs_RS03765	COG1703	isobutyryl-CoA mutase activity
dqs_RS03765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_RS03765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_RS03780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
dqs_RS03790	COG4452	Inner membrane protein CreD
dqs_RS03795	COG2205	protein histidine kinase activity
dqs_RS03800	COG0745	RESPONSE REGULATOR receiver
dqs_RS03805	COG2239	Acts as a magnesium transporter
dqs_RS03810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
dqs_RS03815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
dqs_RS03825	COG0557	exoribonuclease II activity
dqs_RS03835	COG3150	esterase
dqs_RS03840	COG1968	undecaprenyl-diphosphatase activity
dqs_RS03860	COG1643	Atp-dependent helicase
dqs_RS03870	COG0360	Binds together with S18 to 16S ribosomal RNA
dqs_RS03875	COG2965	DNA replication, synthesis of RNA primer
dqs_RS03880	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
dqs_RS03885	COG0359	binds to the 23S rRNA
dqs_RS03890	COG0305	Participates in initiation and elongation during chromosome replication
dqs_RS03920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_RS03925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
dqs_RS03930	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
dqs_RS03940	COG0494	nUDIX hydrolase
dqs_RS03945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
dqs_RS03950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
dqs_RS03955	COG0237	dephospho-CoA kinase activity
dqs_RS03965	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
dqs_RS03970	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
dqs_RS03970	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
dqs_RS03980	COG3852	Histidine kinase
dqs_RS03990	COG0174	glutamine synthetase
dqs_RS04005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
dqs_RS04010	COG3568	Endonuclease Exonuclease Phosphatase
dqs_RS04015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_RS04020	COG1832	CoA-binding protein
dqs_RS04025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_RS04045	COG0463	Glycosyl transferase, family 2
dqs_RS04060	COG0012	GTP binding
dqs_RS04065	COG0193	aminoacyl-tRNA hydrolase activity
dqs_RS04070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
dqs_RS04075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
dqs_RS04085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
dqs_RS04090	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
dqs_RS04100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
dqs_RS04105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
dqs_RS04110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS04115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
dqs_RS04120	COG0742	ribosomal rna small subunit methyltransferase
dqs_RS04125	COG0612	Peptidase, M16
dqs_RS04130	COG0612	Peptidase, M16
dqs_RS04140	COG2884	Cell division ATP-binding protein ftsE
dqs_RS04145	COG2177	Part of the ABC transporter FtsEX involved in
dqs_RS04155	COG3634	alkyl hydroperoxide reductase activity
dqs_RS04170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
dqs_RS04175	COG1702	phosphate starvation-inducible protein PhoH
dqs_RS04180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
dqs_RS04185	COG4535	Mg2 and Co2 transporter CorC
dqs_RS04190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
dqs_RS04205	COG0752	glycyl-tRNA synthetase alpha subunit
dqs_RS04210	COG0751	glycine-tRNA ligase activity
dqs_RS04215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
dqs_RS04220	COG0204	Acyl-transferase
dqs_RS04230	COG1024	Enoyl-CoA hydratase
dqs_RS04235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
dqs_RS04245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
dqs_RS04295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_RS04305	COG1450	Type ii and iii secretion system protein
dqs_RS04310	COG1127	ABC transporter
dqs_RS04315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_RS04320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
dqs_RS04325	COG2853	Lipoprotein
dqs_RS04340	COG1131	(ABC) transporter
dqs_RS04345	COG0842	Transport permease protein
dqs_RS04355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
dqs_RS04360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
dqs_RS04365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
dqs_RS04370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
dqs_RS04375	COG0436	Aminotransferase
dqs_RS04380	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
dqs_RS04385	COG0280	phosphate acetyltransferase
dqs_RS04385	COG0281	malic enzyme
dqs_RS04395	COG1686	Belongs to the peptidase S11 family
dqs_RS04405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
dqs_RS04415	COG1187	pseudouridine synthase activity
dqs_RS04420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_RS04440	COG0577	efflux transmembrane transporter activity
dqs_RS04440	COG1136	(ABC) transporter
dqs_RS04445	COG1136	(ABC) transporter
dqs_RS04445	COG0577	efflux transmembrane transporter activity
dqs_RS04450	COG0577	efflux transmembrane transporter activity
dqs_RS04450	COG1136	(ABC) transporter
dqs_RS04460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_RS04465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
dqs_RS04470	COG2885	chlorophyll binding
dqs_RS04475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
dqs_RS04480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
dqs_RS04485	COG0351	phosphomethylpyrimidine kinase
dqs_RS04520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
dqs_RS04525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_RS04525	COG0425	Belongs to the sulfur carrier protein TusA family
dqs_RS04545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
dqs_RS04565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
dqs_RS04585	COG2264	protein methyltransferase activity
dqs_RS04590	COG0439	Biotin carboxylase
dqs_RS04595	COG0511	ligase activity, forming carbon-carbon bonds
dqs_RS04600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
dqs_RS04605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_RS04615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
dqs_RS04620	COG2823	Periplasmic or secreted lipoprotein
dqs_RS04625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
dqs_RS04630	COG0792	nuclease activity
dqs_RS04640	COG0418	dihydroorotase activity
dqs_RS04655	COG2001	Belongs to the MraZ family
dqs_RS04660	COG0275	rRNA processing
dqs_RS04675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
dqs_RS04680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
dqs_RS04685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
dqs_RS04690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
dqs_RS04695	COG0772	Belongs to the SEDS family
dqs_RS04700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
dqs_RS04705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
dqs_RS04710	COG1181	Belongs to the D-alanine--D-alanine ligase family
dqs_RS04715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
dqs_RS04725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
dqs_RS04730	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
dqs_RS04745	COG0653	protein targeting
dqs_RS04755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
dqs_RS04760	COG0631	protein serine/threonine phosphatase activity
dqs_RS04780	COG2967	ApaG domain
dqs_RS04795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
dqs_RS04800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
dqs_RS04805	COG1862	Preprotein translocase
dqs_RS04815	COG0343	queuine tRNA-ribosyltransferase activity
dqs_RS04820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
dqs_RS04830	COG0583	DNA-binding transcription factor activity
dqs_RS04840	COG0670	Belongs to the BI1 family
dqs_RS04845	COG4651	solute:proton antiporter activity
dqs_RS04845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
dqs_RS04850	COG1253	flavin adenine dinucleotide binding
dqs_RS04855	COG0861	Integral membrane protein TerC family
dqs_RS04860	COG0825	malonyl-CoA metabolic process
dqs_RS04865	COG0037	tRNA processing
dqs_RS04870	COG4566	intracellular signal transduction
dqs_RS04895	COG0586	Pfam SNARE associated Golgi protein
dqs_RS04900	COG0105	UTP biosynthetic process
dqs_RS04905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
dqs_RS04920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
dqs_RS04925	COG0124	histidyl-tRNA synthetase
dqs_RS04935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
dqs_RS04940	COG1160	GTP binding
dqs_RS04945	COG1923	regulation of RNA biosynthetic process
dqs_RS04950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
dqs_RS04955	COG0330	HflC and HflK could
dqs_RS04960	COG0330	HflC and HflK could
dqs_RS04965	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
dqs_RS04970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
dqs_RS04975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
dqs_RS04990	COG0557	exoribonuclease II activity
dqs_RS04995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
dqs_RS05000	COG3707	response regulator
dqs_RS05005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS05015	COG1116	anion transmembrane transporter activity
dqs_RS05025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_RS05030	COG0243	molybdopterin cofactor binding
dqs_RS05055	COG0551	DNA topoisomerase type I activity
dqs_RS05065	COG0716	FMN binding
dqs_RS05080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
dqs_RS05090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
dqs_RS05095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
dqs_RS05100	COG0723	plastoquinol--plastocyanin reductase activity
dqs_RS05105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
dqs_RS05110	COG2857	Cytochrome c1
dqs_RS05115	COG0625	glutathione transferase activity
dqs_RS05125	COG0438	transferase activity, transferring glycosyl groups
dqs_RS05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_RS05140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
dqs_RS05155	COG4120	Belongs to the binding-protein-dependent transport system permease family
dqs_RS05165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
dqs_RS05170	COG0459	protein refolding
dqs_RS05180	COG0642	Histidine kinase
dqs_RS05185	COG3162	membrane
dqs_RS05320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
dqs_RS05325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
dqs_RS05335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
dqs_RS05360	COG2815	serine threonine protein kinase
dqs_RS05360	COG0515	serine threonine protein kinase
dqs_RS05365	COG0165	Argininosuccinate lyase
dqs_RS05370	COG3275	phosphorelay sensor kinase activity
dqs_RS05380	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
dqs_RS05385	COG0181	hydroxymethylbilane synthase activity
dqs_RS05395	COG2959	enzyme of heme biosynthesis
dqs_RS05405	COG2186	Transcriptional regulator
dqs_RS05410	COG0277	FAD linked oxidase domain protein
dqs_RS05415	COG0277	FAD linked oxidase domain protein
dqs_RS05420	COG0247	lactate metabolic process
dqs_RS05425	COG0631	protein serine/threonine phosphatase activity
dqs_RS05455	COG0513	Belongs to the DEAD box helicase family
dqs_RS05460	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
dqs_RS05465	COG0667	Aldo Keto reductase
dqs_RS05475	COG1653	transport
dqs_RS05480	COG0584	glycerophosphoryl diester phosphodiesterase
dqs_RS05485	COG0142	geranyltranstransferase activity
dqs_RS05495	COG0583	DNA-binding transcription factor activity
dqs_RS05510	COG0564	pseudouridine synthase activity
dqs_RS05525	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS05545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
dqs_RS05550	COG1752	Esterase of the alpha-beta hydrolase superfamily
dqs_RS05555	COG0277	FAD linked oxidase domain protein
dqs_RS05590	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS05595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
dqs_RS05615	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS05620	COG0028	Belongs to the TPP enzyme family
dqs_RS05625	COG0440	acetolactate synthase activity
dqs_RS05630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
dqs_RS05635	COG2814	Major facilitator Superfamily
dqs_RS05640	COG4783	chaperone-mediated protein folding
dqs_RS05645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
dqs_RS05650	COG0066	3-isopropylmalate dehydratase activity
dqs_RS05655	COG0473	3-isopropylmalate dehydrogenase activity
dqs_RS05675	COG0101	tRNA pseudouridine synthase activity
dqs_RS05680	COG0135	phosphoribosylanthranilate isomerase activity
dqs_RS05685	COG0133	tryptophan synthase activity
dqs_RS05690	COG0159	tryptophan synthase activity
dqs_RS05695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
dqs_RS05700	COG0285	dihydrofolate synthase activity
dqs_RS05705	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
dqs_RS05725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_RS05730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
dqs_RS05735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
dqs_RS05750	COG0215	cysteine-tRNA ligase activity
dqs_RS05760	COG0484	heat shock protein binding
dqs_RS05765	COG0443	Heat shock 70 kDa protein
dqs_RS05770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
dqs_RS05780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
dqs_RS05790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
dqs_RS05795	COG0287	Prephenate dehydrogenase
dqs_RS05800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
dqs_RS05810	COG0776	regulation of translation
dqs_RS05820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
dqs_RS05845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
dqs_RS05850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
dqs_RS05855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
dqs_RS05860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
dqs_RS05865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
dqs_RS05870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_RS05870	COG0072	phenylalanine-tRNA ligase activity
dqs_RS05875	COG0776	regulation of translation
dqs_RS05890	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
dqs_RS05895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
dqs_RS05905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
dqs_RS05910	COG2951	lytic endotransglycosylase activity
dqs_RS05925	COG0714	Associated with various cellular activities
dqs_RS05930	COG0123	including yeast histone deacetylase and acetoin utilization protein
dqs_RS05935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
dqs_RS05940	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
dqs_RS05950	COG2850	peptidyl-arginine hydroxylation
dqs_RS05955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_RS05980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
dqs_RS06000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
dqs_RS06010	COG1360	Flagellar Motor Protein
dqs_RS06015	COG2703	oxygen carrier activity
dqs_RS06040	COG2860	membrane
dqs_RS06070	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
dqs_RS06075	COG4638	Rieske (2fe-2S)
dqs_RS06095	COG0411	ABC transporter
dqs_RS06110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
dqs_RS06120	COG0542	response to heat
dqs_RS06125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
dqs_RS06130	COG1278	Cold shock
dqs_RS06135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
dqs_RS06140	COG0227	Belongs to the bacterial ribosomal protein bL28 family
dqs_RS06145	COG2003	Belongs to the UPF0758 family
dqs_RS06150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
dqs_RS06155	COG0756	dUTP diphosphatase activity
dqs_RS06165	COG0446	pyridine nucleotide-disulphide oxidoreductase
dqs_RS06185	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
dqs_RS06195	COG0538	isocitrate dehydrogenase activity
dqs_RS06215	COG1346	cytolysis
dqs_RS06240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
dqs_RS06245	COG0730	response to heat
dqs_RS06250	COG0583	DNA-binding transcription factor activity
dqs_RS06260	COG3622	Belongs to the hyi family
dqs_RS06280	COG1139	Iron-sulfur cluster binding protein
dqs_RS06290	COG0247	lactate metabolic process
dqs_RS06330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_RS06340	COG2116	formate transmembrane transporter activity
dqs_RS06345	COG2815	serine threonine protein kinase
dqs_RS06345	COG0515	serine threonine protein kinase
dqs_RS06355	COG4266	Belongs to the allantoicase family
dqs_RS06385	COG3550	peptidyl-serine autophosphorylation
dqs_RS06395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
dqs_RS06400	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
dqs_RS06410	COG0535	radical SAM domain protein
dqs_RS06435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_RS06440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_RS06445	COG1469	GTP cyclohydrolase I activity
dqs_RS06450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
dqs_RS06455	COG0142	geranyltranstransferase activity
dqs_RS06460	COG1722	exodeoxyribonuclease VII activity
dqs_RS06470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
dqs_RS06475	COG1047	Peptidyl-prolyl cis-trans
dqs_RS06480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
dqs_RS06485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
dqs_RS06490	COG0196	riboflavin kinase activity
dqs_RS06500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_RS06535	COG0803	Belongs to the bacterial solute-binding protein 9 family
dqs_RS06540	COG1121	(ABC) transporter
dqs_RS06545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
dqs_RS06545	COG1321	iron dependent repressor
dqs_RS06550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
dqs_RS06575	COG0459	protein refolding
dqs_RS06585	COG0346	lactoylglutathione lyase activity
dqs_RS06615	COG1294	oxidase, subunit
dqs_RS06630	COG2204	response regulator
dqs_RS06635	COG0723	plastoquinol--plastocyanin reductase activity
dqs_RS06640	COG1132	(ABC) transporter
dqs_RS06650	COG0644	oxidoreductase
dqs_RS06660	COG0641	radical SAM
dqs_RS06675	COG0860	N-Acetylmuramoyl-L-alanine amidase
dqs_RS06680	COG0802	atpase or kinase
dqs_RS06690	COG4948	Mandelate Racemase Muconate Lactonizing
dqs_RS06695	COG0583	DNA-binding transcription factor activity
dqs_RS06710	COG2900	Belongs to the SlyX family
dqs_RS06715	COG0826	peptidase U32
dqs_RS06725	COG2133	pyrroloquinoline quinone binding
dqs_RS06730	COG3300	MHYT domain
dqs_RS06730	COG5001	Diguanylate cyclase
dqs_RS06740	COG0515	serine threonine protein kinase
dqs_RS06755	COG2195	Cleaves the N-terminal amino acid of tripeptides
dqs_RS06765	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
dqs_RS06770	COG1704	LemA family
dqs_RS06775	COG3360	Dodecin
dqs_RS06790	COG0484	heat shock protein binding
dqs_RS06795	COG1607	acyl-coa hydrolase
dqs_RS06800	COG4628	conserved protein (DUF2132)
dqs_RS06805	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
dqs_RS06825	COG1127	ABC transporter
dqs_RS06830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_RS06835	COG0488	(ABC) transporter
dqs_RS06840	COG2226	methyltransferase
dqs_RS06845	COG0386	Belongs to the glutathione peroxidase family
dqs_RS06855	COG1858	cytochrome C peroxidase
dqs_RS06865	COG0583	DNA-binding transcription factor activity
dqs_RS06870	COG1215	transferase activity, transferring glycosyl groups
dqs_RS06885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
dqs_RS06885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
dqs_RS06890	COG0509	glycine decarboxylation via glycine cleavage system
dqs_RS06895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
dqs_RS06925	COG2223	nitrite transmembrane transporter activity
dqs_RS06930	COG0515	serine threonine protein kinase
dqs_RS06930	COG2815	serine threonine protein kinase
dqs_RS06950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
dqs_RS06965	COG0312	modulator of DNA gyrase
dqs_RS07045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_RS07050	COG2824	Alkylphosphonate utilization operon protein PhnA
dqs_RS07060	COG0390	transport system, permease component
dqs_RS07065	COG3842	ATPase activity
dqs_RS07105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
dqs_RS07115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
dqs_RS07120	COG0765	amino acid transport
dqs_RS07125	COG4597	amino acid ABC transporter
dqs_RS07130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_RS07135	COG0583	DNA-binding transcription factor activity
dqs_RS07140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
dqs_RS07145	COG4208	sulfate ABC transporter
dqs_RS07150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
dqs_RS07160	COG2951	lytic endotransglycosylase activity
dqs_RS07180	COG3278	Belongs to the heme-copper respiratory oxidase family
dqs_RS07220	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_RS07225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_RS07230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
dqs_RS07245	COG2217	Heavy metal translocating P-type atpase
dqs_RS07250	COG2608	mercury ion transmembrane transporter activity
dqs_RS07260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
dqs_RS07270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
dqs_RS07270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
dqs_RS07275	COG0347	Belongs to the P(II) protein family
dqs_RS07285	COG0492	ferredoxin-NADP+ reductase activity
dqs_RS07295	COG1674	ftsk spoiiie
dqs_RS07300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
dqs_RS07305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
dqs_RS07315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
dqs_RS07320	COG0840	transmembrane signaling receptor activity
dqs_RS07325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
dqs_RS07330	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_RS07335	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
dqs_RS07350	COG4566	intracellular signal transduction
dqs_RS07355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
dqs_RS07360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
dqs_RS07365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
dqs_RS07370	COG0009	L-threonylcarbamoyladenylate synthase
dqs_RS07380	COG0505	Belongs to the CarA family
dqs_RS07385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
dqs_RS07390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
dqs_RS07405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
dqs_RS07410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
dqs_RS07415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
dqs_RS07420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
dqs_RS07425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
dqs_RS07430	COG0573	inorganic phosphate transmembrane transporter activity
dqs_RS07435	COG0581	inorganic phosphate transmembrane transporter activity
dqs_RS07445	COG0149	triose-phosphate isomerase activity
dqs_RS07460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_RS07465	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_RS07470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_RS07475	COG0649	NAD binding
dqs_RS07480	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
dqs_RS07490	COG1034	ATP synthesis coupled electron transport
dqs_RS07495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
dqs_RS07500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_RS07510	COG0713	ATP synthesis coupled electron transport
dqs_RS07525	COG1007	ATP synthesis coupled electron transport
dqs_RS07535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
dqs_RS07540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
dqs_RS07550	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
dqs_RS07555	COG3259	Nickel-dependent hydrogenase
dqs_RS07570	COG1230	cation diffusion facilitator family transporter
dqs_RS07605	COG0326	Molecular chaperone. Has ATPase activity
dqs_RS07620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS07620	COG0426	domain, Protein
dqs_RS07655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
dqs_RS07660	COG4660	Part of a membrane complex involved in electron transport
dqs_RS07670	COG4658	electron transport chain
dqs_RS07675	COG4656	Part of a membrane complex involved in electron transport
dqs_RS07680	COG2878	Part of a membrane complex involved in electron transport
dqs_RS07720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
dqs_RS07725	COG1360	Flagellar Motor Protein
dqs_RS07735	COG0643	Histidine kinase
dqs_RS07735	COG2198	Histidine kinase
dqs_RS07745	COG0840	transmembrane signaling receptor activity
dqs_RS07755	COG2201	protein-glutamate methylesterase activity
dqs_RS07760	COG0840	transmembrane signaling receptor activity
dqs_RS07765	COG0835	chemotaxis
dqs_RS07765	COG0784	Response regulator, receiver
dqs_RS07770	COG0784	Response regulator, receiver
dqs_RS07770	COG0835	chemotaxis
dqs_RS07775	COG0745	RESPONSE REGULATOR receiver
dqs_RS07780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
dqs_RS07785	COG0643	Histidine kinase
dqs_RS07785	COG0784	Response regulator, receiver
dqs_RS07785	COG2198	Histidine kinase
dqs_RS07795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
dqs_RS07805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
dqs_RS07810	COG1570	exodeoxyribonuclease VII activity
dqs_RS07815	COG0811	peptide transport
dqs_RS07820	COG0848	biopolymer transport protein
dqs_RS07825	COG1663	tetraacyldisaccharide 4'-kinase activity
dqs_RS07830	COG2835	tetraacyldisaccharide 4'-kinase activity
dqs_RS07835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
dqs_RS07840	COG0563	adenylate kinase activity
dqs_RS07855	COG5002	protein histidine kinase activity
dqs_RS07855	COG5001	Diguanylate cyclase
dqs_RS07860	COG2249	NAD(P)H dehydrogenase (quinone) activity
dqs_RS07870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_RS07885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_RS07885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
dqs_RS07890	COG0737	Belongs to the 5'-nucleotidase family
dqs_RS07890	COG1525	nuclease
dqs_RS07890	COG4085	toxin activity
dqs_RS07905	COG2199	diguanylate cyclase activity
dqs_RS07905	COG2200	EAL domain
dqs_RS07905	COG3287	FIST C domain
dqs_RS07910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
dqs_RS07920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
dqs_RS07940	COG0501	Belongs to the peptidase M48B family
dqs_RS07945	COG1196	nuclear chromosome segregation
dqs_RS07995	COG4585	Histidine kinase
dqs_RS08010	COG1032	radical SAM domain protein
dqs_RS08025	COG1136	(ABC) transporter
dqs_RS08040	COG2267	carboxylic ester hydrolase activity
dqs_RS08045	COG2308	Evidence 4 Homologs of previously reported genes of
dqs_RS08060	COG0501	Belongs to the peptidase M48B family
dqs_RS08065	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
dqs_RS08070	COG0166	Belongs to the GPI family
dqs_RS08080	COG0254	rRNA binding
dqs_RS08100	COG0727	PFAM Uncharacterised protein family (UPF0153)
dqs_RS08105	COG0727	PFAM Uncharacterised protein family (UPF0153)
dqs_RS08135	COG3012	SEC-C Motif Domain Protein
dqs_RS08140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
dqs_RS08170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
dqs_RS08175	COG0022	dehydrogenase e1 component
dqs_RS08175	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_RS08185	COG2814	Major facilitator Superfamily
dqs_RS08190	COG0583	DNA-binding transcription factor activity
dqs_RS08210	COG0039	L-malate dehydrogenase activity
dqs_RS08215	COG2188	Transcriptional regulator
dqs_RS08230	COG1053	succinate dehydrogenase
dqs_RS08235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
dqs_RS08240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
dqs_RS08245	COG0372	Belongs to the citrate synthase family
dqs_RS08250	COG0567	Dehydrogenase, E1 component
dqs_RS08255	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_RS08260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
dqs_RS08270	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
dqs_RS08275	COG1199	ATP-dependent helicase activity
dqs_RS08280	COG1763	Mo-molybdopterin cofactor biosynthetic process
dqs_RS08285	COG0303	'Molybdopterin
dqs_RS08290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
dqs_RS08295	COG0314	molybdopterin synthase activity
dqs_RS08305	COG0542	response to heat
dqs_RS08315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_RS08325	COG3781	membrane
dqs_RS08330	COG0747	negative chemotaxis
dqs_RS08335	COG0601	transmembrane transport
dqs_RS08340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
dqs_RS08345	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
dqs_RS08355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
dqs_RS08360	COG2867	negative regulation of translational initiation
dqs_RS08365	COG2914	Belongs to the UPF0125 (RnfH) family
dqs_RS08380	COG0519	Catalyzes the synthesis of GMP from XMP
dqs_RS08380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
dqs_RS08385	COG0583	DNA-binding transcription factor activity
dqs_RS08410	COG5002	protein histidine kinase activity
dqs_RS08420	COG1376	ErfK ybiS ycfS ynhG family protein
dqs_RS08445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
dqs_RS08450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
dqs_RS08465	COG0084	hydrolase, TatD family'
dqs_RS08485	COG1305	Transglutaminase-like
dqs_RS08490	COG2307	Protein conserved in bacteria
dqs_RS08490	COG2308	Evidence 4 Homologs of previously reported genes of
dqs_RS08500	COG1473	amidohydrolase
dqs_RS08505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
dqs_RS08510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
dqs_RS08520	COG1067	ATP-dependent peptidase activity
dqs_RS08540	COG0556	nucleotide-excision repair
dqs_RS08545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
dqs_RS08550	COG1530	ribonuclease E activity
dqs_RS08555	COG0564	pseudouridine synthase activity
dqs_RS08560	COG0546	phosphoglycolate phosphatase activity
dqs_RS08570	COG0616	signal peptide processing
dqs_RS08575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
dqs_RS08580	COG0424	maF-like protein
dqs_RS08585	COG1399	metal-binding, possibly nucleic acid-binding protein
dqs_RS08590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
dqs_RS08595	COG0416	fatty acid biosynthetic process
dqs_RS08600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
dqs_RS08605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
dqs_RS08615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_RS08620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
dqs_RS08630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
dqs_RS08655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS08665	COG0583	DNA-binding transcription factor activity
dqs_RS08675	COG3181	Tripartite tricarboxylate transporter family receptor
dqs_RS08680	COG0481	GTPase activity
dqs_RS08685	COG0681	Belongs to the peptidase S26 family
dqs_RS08695	COG0571	ribonuclease III activity
dqs_RS08700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
dqs_RS08705	COG1381	Involved in DNA repair and RecF pathway recombination
dqs_RS08710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
dqs_RS08715	COG0736	holo-[acyl-carrier-protein] synthase activity
dqs_RS08720	COG1472	Belongs to the glycosyl hydrolase 3 family
dqs_RS08725	COG0322	excinuclease ABC activity
dqs_RS08730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
dqs_RS08855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
dqs_RS08865	COG0850	regulation of cytokinetic process
dqs_RS08870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
dqs_RS08875	COG1393	Belongs to the ArsC family
dqs_RS08880	COG2183	response to ionizing radiation
dqs_RS08905	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
dqs_RS08920	COG4181	ATPase activity
dqs_RS08925	COG0560	Phosphoserine phosphatase
dqs_RS08930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
dqs_RS08945	COG0598	Magnesium transport protein CorA
dqs_RS08950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
dqs_RS08980	COG2078	PFAM AMMECR1 domain protein
dqs_RS08985	COG1355	regulation of microtubule-based process
dqs_RS08990	COG3174	membrane
dqs_RS08995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
dqs_RS09000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
dqs_RS09025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
dqs_RS09030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
dqs_RS09035	COG0248	Ppx GppA phosphatase
dqs_RS09040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_RS09045	COG1127	ABC transporter
dqs_RS09050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
dqs_RS09050	COG3218	ABC-type transport auxiliary lipoprotein component
dqs_RS09060	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS09070	COG0084	hydrolase, TatD family'
dqs_RS09075	COG1309	transcriptional regulator
dqs_RS09095	COG1960	acyl-CoA dehydrogenase activity
dqs_RS09100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_RS09110	COG2350	Protein conserved in bacteria
dqs_RS09115	COG2917	probably involved in intracellular septation
dqs_RS09145	COG0456	acetyltransferase
dqs_RS09150	COG1573	uracil-dna glycosylase
dqs_RS09155	COG0477	Major facilitator Superfamily
dqs_RS09160	COG0583	DNA-binding transcription factor activity
dqs_RS09200	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
dqs_RS09210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_RS09215	COG0366	Alpha amylase catalytic
dqs_RS09220	COG0366	Alpha amylase catalytic
dqs_RS09225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
dqs_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS09285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
dqs_RS09310	COG0189	ligase activity
dqs_RS09350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_RS09365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
dqs_RS09365	COG2010	Cytochrome c
dqs_RS09370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
dqs_RS09395	COG0628	permease
dqs_RS09400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS09410	COG5487	UPF0391 membrane protein
dqs_RS09415	COG1252	NADH dehydrogenase
dqs_RS09440	COG1271	oxidase subunit
dqs_RS09445	COG1294	oxidase, subunit
dqs_RS09470	COG3023	N-Acetylmuramoyl-L-alanine amidase
dqs_RS09490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_RS09505	COG0671	phosphoesterase, PA-phosphatase related
dqs_RS09515	COG0438	transferase activity, transferring glycosyl groups
dqs_RS09525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
dqs_RS09555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_RS09560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
dqs_RS09565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_RS09570	COG1640	4-alpha-glucanotransferase
dqs_RS09580	COG0297	glycogen (starch) synthase activity
dqs_RS09585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_RS09605	COG0859	PFAM glycosyl transferase family 9
dqs_RS09610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
dqs_RS09620	COG0297	glycogen (starch) synthase activity
dqs_RS09630	COG2323	membrane
dqs_RS09635	COG2204	response regulator
dqs_RS09660	COG2205	protein histidine kinase activity
dqs_RS09665	COG1295	ribonuclease BN
dqs_RS09680	COG5265	(ABC) transporter
dqs_RS09695	COG1546	Belongs to the CinA family
dqs_RS09695	COG1058	Belongs to the CinA family
dqs_RS09715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
dqs_RS09715	COG1017	nitric oxide dioxygenase activity
dqs_RS09725	COG4771	TonB-dependent receptor
dqs_RS09745	COG1252	NADH dehydrogenase
dqs_RS09860	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_RS09865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_RS09930	COG0564	pseudouridine synthase activity
dqs_RS09965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
dqs_RS09970	COG1091	dTDP-4-dehydrorhamnose reductase activity
dqs_RS10000	COG4181	ATPase activity
dqs_RS10015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
dqs_RS10020	COG2866	Carboxypeptidase
dqs_RS10025	COG3022	response to hydroperoxide
dqs_RS10035	COG0156	8-amino-7-oxononanoate synthase activity
dqs_RS10040	COG2267	carboxylic ester hydrolase activity
dqs_RS10045	COG2226	methyltransferase
dqs_RS10050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
dqs_RS10055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
dqs_RS10065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
dqs_RS10070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_RS10075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_RS10080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
dqs_RS10085	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_RS10105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
dqs_RS10110	COG0575	Belongs to the CDS family
dqs_RS10115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
dqs_RS10120	COG0233	cytoplasmic translational termination
dqs_RS10125	COG0528	UMP kinase activity
dqs_RS10130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
dqs_RS10135	COG0052	Belongs to the universal ribosomal protein uS2 family
dqs_RS10145	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
dqs_RS10155	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
dqs_RS10160	COG2204	response regulator
dqs_RS10165	COG4191	Histidine kinase
dqs_RS10180	COG2358	TRAP transporter, solute receptor (TAXI family
dqs_RS10185	COG0579	oxidoreductase
dqs_RS10205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
dqs_RS10210	COG1960	acyl-CoA dehydrogenase activity
dqs_RS10215	COG0583	DNA-binding transcription factor activity
dqs_RS10225	COG1024	Enoyl-CoA hydratase
dqs_RS10240	COG1960	acyl-CoA dehydrogenase activity
dqs_RS10245	COG1960	acyl-CoA dehydrogenase activity
dqs_RS10250	COG1024	Enoyl-CoA hydratase
dqs_RS10265	COG1846	Transcriptional regulator
dqs_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS10285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS10290	COG2354	Protein conserved in bacteria
dqs_RS10305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS10310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_RS10320	COG0243	molybdopterin cofactor binding
dqs_RS10325	COG0437	4 iron, 4 sulfur cluster binding
dqs_RS10390	COG0543	2 iron, 2 sulfur cluster binding
dqs_RS10390	COG0633	Ferredoxin
dqs_RS10400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS10410	COG2207	Transcriptional regulator
dqs_RS10435	COG1802	Transcriptional regulator
dqs_RS10445	COG1063	alcohol dehydrogenase
dqs_RS10450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_RS10455	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_RS10460	COG3971	2-oxopent-4-enoate hydratase activity
dqs_RS10465	COG3384	dioxygenase
dqs_RS10470	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_RS10470	COG0596	Alpha beta hydrolase
dqs_RS10480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
dqs_RS10505	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
dqs_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS10525	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
dqs_RS10555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_RS10585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
dqs_RS10590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
dqs_RS10600	COG1196	nuclear chromosome segregation
dqs_RS10605	COG0436	Aminotransferase
dqs_RS10610	COG2171	N-acyltransferase activity
dqs_RS10620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
dqs_RS10630	COG0784	Response regulator, receiver
dqs_RS10640	COG0633	Ferredoxin
dqs_RS10645	COG0443	Heat shock 70 kDa protein
dqs_RS10650	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
dqs_RS10660	COG0822	iron-sulfur transferase activity
dqs_RS10665	COG1104	cysteine desulfurase activity
dqs_RS10670	COG1104	cysteine desulfurase activity
dqs_RS10680	COG1045	serine acetyltransferase
dqs_RS10690	COG0483	inositol monophosphate 1-phosphatase activity
dqs_RS10700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
dqs_RS10715	COG0328	RNA-DNA hybrid ribonuclease activity
dqs_RS10720	COG2226	methyltransferase
dqs_RS10725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_RS10735	COG4251	negative regulation of phosphorylation
dqs_RS10735	COG5001	Diguanylate cyclase
dqs_RS10735	COG3706	GGDEF domain
dqs_RS10735	COG2203	Gaf domain
dqs_RS10740	COG1388	LysM domain
dqs_RS10740	COG0741	lytic transglycosylase activity
dqs_RS10745	COG4172	Belongs to the ABC transporter superfamily
dqs_RS10750	COG1047	Peptidyl-prolyl cis-trans
dqs_RS10755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_RS10760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
dqs_RS10770	COG0534	Mate efflux family protein
dqs_RS10775	COG1393	Belongs to the ArsC family
dqs_RS10800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
dqs_RS10805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
dqs_RS10810	COG0740	serine-type endopeptidase activity
dqs_RS10815	COG0544	peptidyl-prolyl cis-trans isomerase activity
dqs_RS10820	COG2766	serine protein kinase
dqs_RS10825	COG2718	Belongs to the UPF0229 family
dqs_RS10830	COG2719	SpoVR family
dqs_RS10835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
dqs_RS10835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
dqs_RS10865	COG0436	Aminotransferase
dqs_RS10900	COG4968	Prepilin-type N-terminal cleavage methylation domain
dqs_RS10905	COG4796	Type ii and iii secretion system protein
dqs_RS10935	COG1459	type II secretion system
dqs_RS10940	COG2165	general secretion pathway protein
dqs_RS10945	COG1196	nuclear chromosome segregation
dqs_RS10945	COG0739	heme binding
dqs_RS10945	COG0741	lytic transglycosylase activity
dqs_RS10955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
dqs_RS10980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
dqs_RS10985	COG1185	polyribonucleotide nucleotidyltransferase activity
dqs_RS10990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
dqs_RS10995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
dqs_RS11000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
dqs_RS11005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
dqs_RS11010	COG2251	uridine kinase activity
dqs_RS11010	COG0195	Participates in both transcription termination and antitermination
dqs_RS11015	COG0779	Required for maturation of 30S ribosomal subunits
dqs_RS11020	COG1187	pseudouridine synthase activity
dqs_RS11025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
dqs_RS11030	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
dqs_RS11035	COG1994	Peptidase M50
dqs_RS11040	COG0009	L-threonylcarbamoyladenylate synthase
dqs_RS11045	COG0613	PHP domain protein
dqs_RS11065	COG1012	belongs to the aldehyde dehydrogenase family
dqs_RS11070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
dqs_RS11075	COG1278	Cold shock
dqs_RS11110	COG3706	GGDEF domain
dqs_RS11120	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
dqs_RS11130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
dqs_RS11135	COG0302	gtp cyclohydrolase
dqs_RS11145	COG0306	phosphate transporter
dqs_RS11155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
dqs_RS11175	COG0791	NLP P60 protein
dqs_RS11185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
dqs_RS11190	COG0148	phosphopyruvate hydratase activity
dqs_RS11195	COG2877	3-deoxy-8-phosphooctulonate synthase activity
dqs_RS11200	COG0504	CTP synthase activity
dqs_RS11215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_RS11220	COG0824	Thioesterase
dqs_RS11260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
dqs_RS11260	COG0047	phosphoribosylformylglycinamidine synthase activity
dqs_RS11265	COG0671	phosphoesterase, PA-phosphatase related
dqs_RS11275	COG0463	Glycosyl transferase, family 2
dqs_RS11300	COG0739	heme binding
dqs_RS11310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
dqs_RS11320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
dqs_RS11325	COG0840	transmembrane signaling receptor activity
dqs_RS11330	COG0183	Belongs to the thiolase family
dqs_RS11335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
dqs_RS11340	COG0494	nUDIX hydrolase
dqs_RS11365	COG4969	Belongs to the N-Me-Phe pilin family
dqs_RS11385	COG1666	GTP binding
dqs_RS11390	COG3123	guanosine phosphorylase activity
dqs_RS11400	COG0137	argininosuccinate synthase activity
dqs_RS11405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
dqs_RS11410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_RS11420	COG0268	Binds directly to 16S ribosomal RNA
dqs_RS11445	COG2081	HI0933 family
dqs_RS11455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_RS11460	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
dqs_RS11465	COG0840	transmembrane signaling receptor activity
dqs_RS11485	COG0791	NLP P60 protein
dqs_RS11495	COG1840	ABC-type Fe3 transport system, periplasmic component
dqs_RS11500	COG1178	ABC-type Fe3 transport system permease component
dqs_RS11505	COG3842	ATPase activity
dqs_RS11510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
dqs_RS11515	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
dqs_RS11520	COG0167	dihydroorotate dehydrogenase activity
dqs_RS11540	COG3845	ABC transporter
dqs_RS11545	COG4603	Belongs to the binding-protein-dependent transport system permease family
dqs_RS11550	COG1079	Belongs to the binding-protein-dependent transport system permease family
dqs_RS11555	COG4772	TonB-dependent receptor
dqs_RS11565	COG0310	cobalt ion transport
dqs_RS11570	COG0310	cobalt ion transport
dqs_RS11580	COG1122	ATPase activity
dqs_RS11585	COG0402	S-adenosylhomocysteine deaminase activity
dqs_RS11590	COG1671	Belongs to the UPF0178 family
dqs_RS11610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_RS11625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
dqs_RS11645	COG0438	transferase activity, transferring glycosyl groups
dqs_RS11650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
dqs_RS11655	COG0438	transferase activity, transferring glycosyl groups
dqs_RS11670	COG0489	protein tyrosine kinase activity
dqs_RS11700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
dqs_RS11715	COG1012	belongs to the aldehyde dehydrogenase family
dqs_RS11730	COG2409	Drug exporters of the RND superfamily
dqs_RS11755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_RS11760	COG2259	Doxx family
dqs_RS11790	COG0765	amino acid transport
dqs_RS11795	COG1126	abc transporter atp-binding protein
dqs_RS11825	COG3158	transport of potassium into the cell
dqs_RS11830	COG0657	acetylesterase activity
dqs_RS11835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
dqs_RS11840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
dqs_RS11845	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
dqs_RS11860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_RS11880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
dqs_RS11885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_RS11905	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
dqs_RS11920	COG0121	glutamine amidotransferase
dqs_RS11930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
dqs_RS11930	COG2169	Transcriptional regulator
dqs_RS11950	COG2154	pterin-4-alpha-carbinolamine dehydratase
dqs_RS11965	COG1960	acyl-CoA dehydrogenase activity
dqs_RS11975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_RS12000	COG0366	Alpha amylase catalytic
dqs_RS12015	COG0837	glucose binding
dqs_RS12030	COG1132	(ABC) transporter
dqs_RS12060	COG0297	glycogen (starch) synthase activity
dqs_RS12065	COG0438	transferase activity, transferring glycosyl groups
dqs_RS12070	COG0726	polysaccharide deacetylase
dqs_RS12085	COG0583	DNA-binding transcription factor activity
dqs_RS12090	COG3829	transcription factor binding
dqs_RS12120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_RS12130	COG1538	Outer membrane efflux protein
dqs_RS12140	COG0793	Belongs to the peptidase S41A family
dqs_RS12190	COG4771	TonB-dependent receptor
dqs_RS12220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
dqs_RS12225	COG0798	PFAM Bile acid sodium symporter
dqs_RS12240	COG0154	amidase activity
dqs_RS12250	COG1942	4-Oxalocrotonate Tautomerase
dqs_RS12255	COG0583	DNA-binding transcription factor activity
dqs_RS12270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
dqs_RS12280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
dqs_RS12285	COG0459	protein refolding
dqs_RS12310	COG2391	methyltransferase activity
dqs_RS12315	COG2897	thiosulfate sulfurtransferase activity
dqs_RS12330	COG3001	Fructosamine kinase
dqs_RS12335	COG0463	Glycosyl transferase, family 2
dqs_RS12385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_RS12390	COG0235	Class ii aldolase
dqs_RS12400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_RS12410	COG1024	Enoyl-CoA hydratase
dqs_RS12450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_RS12455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS12460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_RS12465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS12480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS12485	COG1116	anion transmembrane transporter activity
dqs_RS12490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_RS12520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
dqs_RS12535	COG0784	Response regulator, receiver
dqs_RS12535	COG2205	protein histidine kinase activity
dqs_RS12535	COG5002	protein histidine kinase activity
dqs_RS12540	COG3706	GGDEF domain
dqs_RS12540	COG4251	negative regulation of phosphorylation
dqs_RS12540	COG5001	Diguanylate cyclase
dqs_RS12540	COG2203	Gaf domain
dqs_RS12550	COG1764	response to oxidative stress
dqs_RS12560	COG1522	sequence-specific DNA binding
dqs_RS12570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_RS12575	COG2176	DNA-directed DNA polymerase activity
dqs_RS12575	COG5002	protein histidine kinase activity
dqs_RS12580	COG0745	RESPONSE REGULATOR receiver
dqs_RS12585	COG5002	protein histidine kinase activity
dqs_RS12595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_RS12615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
dqs_RS12635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_RS12645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_RS12650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
dqs_RS12650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_RS12655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_RS12680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_RS12685	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS12710	COG1802	Transcriptional regulator
dqs_RS12760	COG0745	RESPONSE REGULATOR receiver
dqs_RS12760	COG2205	protein histidine kinase activity
dqs_RS12760	COG3292	Two component regulator propeller
dqs_RS12775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_RS12775	COG2205	protein histidine kinase activity
dqs_RS12805	COG2205	protein histidine kinase activity
dqs_RS12805	COG2202	Pas domain
dqs_RS12865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
dqs_RS12895	COG0028	Belongs to the TPP enzyme family
dqs_RS12900	COG0583	DNA-binding transcription factor activity
dqs_RS12905	COG0348	domain, Protein
dqs_RS12925	COG0446	pyridine nucleotide-disulphide oxidoreductase
dqs_RS12930	COG1116	anion transmembrane transporter activity
dqs_RS12930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS12935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_RS12940	COG1116	anion transmembrane transporter activity
dqs_RS12940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS12945	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
dqs_RS12980	COG0784	Response regulator, receiver
dqs_RS12980	COG2205	protein histidine kinase activity
dqs_RS12980	COG5002	protein histidine kinase activity
dqs_RS12990	COG3437	response regulator, receiver
dqs_RS13015	COG0490	domain, Protein
dqs_RS13015	COG0471	metal ion transport
dqs_RS13020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_RS13040	COG1960	acyl-CoA dehydrogenase activity
dqs_RS13055	COG0183	Belongs to the thiolase family
dqs_RS13060	COG1024	Enoyl-CoA hydratase
dqs_RS13065	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS13090	COG1309	transcriptional regulator
dqs_RS13095	COG1309	transcriptional regulator
dqs_RS13140	COG3486	L-lysine 6-monooxygenase (NADPH) activity
dqs_RS13210	COG0583	DNA-binding transcription factor activity
dqs_RS13225	COG2124	cytochrome p450
dqs_RS13230	COG0633	Ferredoxin
dqs_RS13245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
dqs_RS13265	COG0667	Aldo Keto reductase
dqs_RS13300	COG2159	amidohydrolase
dqs_RS13305	COG2814	Major facilitator Superfamily
dqs_RS13315	COG2814	Major facilitator Superfamily
dqs_RS13335	COG0617	tRNA 3'-terminal CCA addition
dqs_RS13405	COG1858	cytochrome C peroxidase
dqs_RS13435	COG5001	Diguanylate cyclase
dqs_RS13435	COG5002	protein histidine kinase activity
dqs_RS13440	COG0583	DNA-binding transcription factor activity
dqs_RS13445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_RS13485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
dqs_RS13490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
dqs_RS13495	COG0735	belongs to the Fur family
dqs_RS13500	COG0497	DNA recombination
dqs_RS13505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
dqs_RS13510	COG1420	regulation of RNA biosynthetic process
dqs_RS13515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
dqs_RS13520	COG1950	PFAM Membrane protein of
dqs_RS13530	COG2815	serine threonine protein kinase
dqs_RS13530	COG0515	serine threonine protein kinase
dqs_RS13535	COG0402	S-adenosylhomocysteine deaminase activity
dqs_RS13545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
dqs_RS13575	COG1858	cytochrome C peroxidase
dqs_RS13580	COG1858	cytochrome C peroxidase
dqs_RS13605	COG0583	DNA-binding transcription factor activity
dqs_RS13615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
dqs_RS13620	COG1278	Cold shock
dqs_RS13640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_RS13645	COG0235	Class ii aldolase
dqs_RS13665	COG5001	Diguanylate cyclase
dqs_RS13665	COG5002	protein histidine kinase activity
dqs_RS13665	COG3447	MASE1 domain protein
dqs_RS13690	COG0546	phosphoglycolate phosphatase activity
dqs_RS13695	COG0789	Transcriptional regulator
dqs_RS13720	COG1429	ligase activity, forming nitrogen-metal bonds
dqs_RS13735	COG4106	trans-aconitate 2-methyltransferase activity
dqs_RS13750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
dqs_RS13755	COG0412	Dienelactone hydrolase
dqs_RS13800	COG1742	UPF0060 membrane protein
dqs_RS13820	COG1881	PFAM PEBP family protein
dqs_RS13835	COG0450	alkyl hydroperoxide reductase
dqs_RS13855	COG1902	pentaerythritol trinitrate reductase activity
dqs_RS13860	COG3258	Cytochrome c
dqs_RS13870	COG4566	intracellular signal transduction
dqs_RS13875	COG4191	Histidine kinase
dqs_RS13900	COG3045	CreA protein
dqs_RS13950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
dqs_RS13960	COG1454	alcohol dehydrogenase
dqs_RS13965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
dqs_RS13990	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
dqs_RS14010	COG2257	FlhB HrpN YscU SpaS Family
dqs_RS14015	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
dqs_RS14025	COG1677	Flagellar hook-basal body complex protein FliE
dqs_RS14055	COG1157	protein secretion by the type III secretion system
dqs_RS14075	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
dqs_RS14080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
dqs_RS14090	COG1338	Plays a role in the flagellum-specific transport system
dqs_RS14120	COG3951	Flagellar rod assembly protein muramidase FlgJ
dqs_RS14120	COG1705	Flagellar rod assembly protein muramidase FlgJ
dqs_RS14125	COG1706	bacterial-type flagellum-dependent cell motility
dqs_RS14130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
dqs_RS14140	COG4787	bacterial-type flagellum-dependent cell motility
dqs_RS14155	COG1558	bacterial-type flagellum-dependent cell motility
dqs_RS14160	COG1815	bacterial-type flagellum-dependent cell motility
dqs_RS14210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
dqs_RS14215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
dqs_RS14235	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
dqs_RS14240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
dqs_RS14245	COG0739	heme binding
dqs_RS14250	COG0316	Belongs to the HesB IscA family
dqs_RS14255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
dqs_RS14260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
dqs_RS14270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
dqs_RS14280	COG0494	nUDIX hydrolase
dqs_RS14285	COG0442	prolyl-tRNA aminoacylation
dqs_RS14290	COG0741	lytic transglycosylase activity
dqs_RS14300	COG2205	protein histidine kinase activity
dqs_RS14310	COG2204	response regulator
dqs_RS14320	COG0482	sulfurtransferase activity
dqs_RS14360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
dqs_RS14365	COG2096	Adenosyltransferase
dqs_RS14385	COG1132	(ABC) transporter
dqs_RS14390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
dqs_RS14400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
dqs_RS14410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
dqs_RS14415	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
dqs_RS14420	COG0521	Mo-molybdopterin cofactor biosynthetic process
dqs_RS14425	COG3028	Belongs to the UPF0307 family
dqs_RS14430	COG0312	modulator of DNA gyrase
dqs_RS14435	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
dqs_RS14440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_RS14455	COG2205	protein histidine kinase activity
dqs_RS14460	COG0745	RESPONSE REGULATOR receiver
dqs_RS14465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS14490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
dqs_RS14495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
dqs_RS14500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
dqs_RS14500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
dqs_RS14505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
dqs_RS14515	COG0793	Belongs to the peptidase S41A family
dqs_RS14525	COG0588	phosphoglycerate mutase activity
dqs_RS14535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_RS14545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
dqs_RS14555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
dqs_RS14560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
dqs_RS14565	COG1040	competence protein
dqs_RS14570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
dqs_RS14575	COG2226	methyltransferase
dqs_RS14595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
dqs_RS14605	COG2833	Protein of unknown function (DUF455)
dqs_RS14610	COG0303	'Molybdopterin
dqs_RS14615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
dqs_RS14620	COG0704	Plays a role in the regulation of phosphate uptake
dqs_RS14625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
dqs_RS14635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
dqs_RS14635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
dqs_RS14645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
dqs_RS14650	COG0483	inositol monophosphate 1-phosphatase activity
dqs_RS14665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
dqs_RS14670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
dqs_RS14680	COG0126	phosphoglycerate kinase activity
dqs_RS14695	COG0469	pyruvate kinase activity
dqs_RS14715	COG3284	Transcriptional regulator
dqs_RS14735	COG0477	Major facilitator Superfamily
dqs_RS14755	COG3220	belongs to the UPF0276 family
dqs_RS14765	COG2259	Doxx family
dqs_RS14770	COG1595	DNA-templated transcription, initiation
dqs_RS14785	COG2304	oxidoreductase activity
dqs_RS14795	COG0714	Associated with various cellular activities
dqs_RS14800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS14805	COG2304	oxidoreductase activity
dqs_RS14820	COG0583	DNA-binding transcription factor activity
dqs_RS14825	COG3384	dioxygenase
dqs_RS14830	COG3038	cytochrome b561
dqs_RS14840	COG2353	YceI-like domain
dqs_RS14850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
dqs_RS14870	COG0339	signal peptide processing
dqs_RS14875	COG1393	Belongs to the ArsC family
dqs_RS14880	COG0004	ammonium transporteR
dqs_RS14895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_RS14905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
dqs_RS14910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
dqs_RS14915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_RS14920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
dqs_RS14935	COG0006	proline dipeptidase activity
dqs_RS14940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_RS14950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
dqs_RS14955	COG0138	bifunctional purine biosynthesis protein purh
dqs_RS14960	COG0151	Belongs to the GarS family
dqs_RS14965	COG0408	coproporphyrinogen oxidase activity
dqs_RS14975	COG0228	four-way junction DNA binding
dqs_RS14980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
dqs_RS14985	COG0336	Belongs to the RNA methyltransferase TrmD family
dqs_RS14990	COG0335	large ribosomal subunit rRNA binding
dqs_RS15000	COG0795	lipopolysaccharide-transporting ATPase activity
dqs_RS15005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
dqs_RS15020	COG0525	valine-tRNA ligase activity
dqs_RS15030	COG0842	Transport permease protein
dqs_RS15035	COG0842	Transport permease protein
dqs_RS15035	COG1129	ABC transporter
dqs_RS15040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_RS15080	COG0425	Belongs to the sulfur carrier protein TusA family
dqs_RS15090	COG0315	cyclic pyranopterin monophosphate synthase activity
dqs_RS15100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
dqs_RS15130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_RS15135	COG2414	aldehyde ferredoxin oxidoreductase
dqs_RS15145	COG3284	Transcriptional regulator
dqs_RS15165	COG3038	cytochrome b561
dqs_RS15170	COG4654	Cytochrome c, class I
dqs_RS15180	COG1012	belongs to the aldehyde dehydrogenase family
dqs_RS15185	COG3284	Transcriptional regulator
dqs_RS15210	COG5002	protein histidine kinase activity
dqs_RS15230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_RS15275	COG1595	DNA-templated transcription, initiation
dqs_RS15290	COG1741	Belongs to the pirin family
dqs_RS15295	COG2259	Doxx family
dqs_RS15300	COG0583	DNA-binding transcription factor activity
dqs_RS15305	COG0655	NAD(P)H dehydrogenase (quinone) activity
dqs_RS15315	COG2197	response regulator
dqs_RS15360	COG3851	Histidine kinase
dqs_RS15365	COG2197	response regulator
dqs_RS15370	COG0840	transmembrane signaling receptor activity
dqs_RS15390	COG4106	trans-aconitate 2-methyltransferase activity
dqs_RS15405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
dqs_RS15410	COG1335	isochorismatase
dqs_RS15420	COG0583	DNA-binding transcription factor activity
dqs_RS15430	COG4773	Receptor
dqs_RS15445	COG4774	siderophore transport
dqs_RS15455	COG3108	Peptidase M15
dqs_RS15460	COG2989	Protein conserved in bacteria
dqs_RS15475	COG0583	DNA-binding transcription factor activity
dqs_RS15515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
dqs_RS15525	COG0069	glutamate synthase activity
dqs_RS15535	COG0004	ammonium transporteR
dqs_RS15560	COG1012	belongs to the aldehyde dehydrogenase family
dqs_RS15570	COG4772	TonB-dependent receptor
dqs_RS15580	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
dqs_RS15640	COG3383	formate dehydrogenase (NAD+) activity
dqs_RS15650	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS15655	COG1773	rubredoxin
dqs_RS15660	COG3321	synthase
dqs_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS15660	COG0604	alcohol dehydrogenase
dqs_RS15665	COG1024	Enoyl-CoA hydratase
dqs_RS15725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
dqs_RS15745	COG0183	Belongs to the thiolase family
dqs_RS15780	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS15785	COG2852	Protein conserved in bacteria
dqs_RS15795	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS15795	COG1024	Enoyl-CoA hydratase
dqs_RS15800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
dqs_RS15850	COG1960	acyl-CoA dehydrogenase activity
dqs_RS15885	COG2010	Cytochrome c
dqs_RS15920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
dqs_RS15930	COG1959	2 iron, 2 sulfur cluster binding
dqs_RS15935	COG2239	Acts as a magnesium transporter
dqs_RS15940	COG3245	cytochrome
dqs_RS15990	COG4263	nitrous-oxide reductase activity
dqs_RS16005	COG0527	aspartate kinase activity
dqs_RS16020	COG0720	synthase
dqs_RS16030	COG1511	domain protein
dqs_RS16030	COG3264	Mechanosensitive ion channel
dqs_RS16035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_RS16040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
dqs_RS16040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
dqs_RS16050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
dqs_RS16060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
dqs_RS16070	COG0864	Transcriptional regulator
dqs_RS16080	COG1793	dna ligase
dqs_RS16085	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
dqs_RS16100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_RS16110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
dqs_RS16115	COG0628	permease
dqs_RS16120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
dqs_RS16130	COG0617	tRNA 3'-terminal CCA addition
dqs_RS16145	COG1428	Deoxynucleoside kinase
dqs_RS16150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
dqs_RS16155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
dqs_RS16160	COG0517	IMP dehydrogenase activity
dqs_RS16160	COG0516	GMP reductase activity
dqs_RS16165	COG0308	aminopeptidase N
dqs_RS16200	COG0028	Belongs to the TPP enzyme family
dqs_RS16205	COG0440	acetolactate synthase activity
dqs_RS16210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
dqs_RS16215	COG1183	phosphatidylcholine synthase activity
dqs_RS16225	COG2198	Histidine kinase
dqs_RS16225	COG0784	Response regulator, receiver
dqs_RS16225	COG2205	protein histidine kinase activity
dqs_RS16235	COG3642	lipopolysaccharide core region biosynthetic process
dqs_RS16240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_RS16255	COG1295	ribonuclease BN
dqs_RS16265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
dqs_RS16270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
dqs_RS16275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
dqs_RS16280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
dqs_RS16295	COG3320	Male sterility
dqs_RS16295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_RS16300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
dqs_RS16310	COG4591	ABC-type transport system involved in lipoprotein release permease component
dqs_RS16315	COG1136	(ABC) transporter
dqs_RS16315	COG0577	efflux transmembrane transporter activity
dqs_RS16320	COG3916	Acyl-homoserine-lactone synthase
dqs_RS16325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_RS16335	COG0604	alcohol dehydrogenase
dqs_RS16345	COG1704	LemA family
dqs_RS16355	COG0488	(ABC) transporter
dqs_RS16375	COG0741	lytic transglycosylase activity
dqs_RS16375	COG1196	nuclear chromosome segregation
dqs_RS16375	COG0739	heme binding
dqs_RS16390	COG2204	response regulator
dqs_RS16400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
dqs_RS16405	COG2030	dehydratase
dqs_RS16440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
dqs_RS16455	COG0717	Belongs to the dCTP deaminase family
dqs_RS16460	COG0489	protein tyrosine kinase activity
dqs_RS16465	COG3047	cAMP biosynthetic process
dqs_RS16465	COG2885	chlorophyll binding
dqs_RS16470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_RS16470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_RS16475	COG0659	secondary active sulfate transmembrane transporter activity
dqs_RS16480	COG1254	Belongs to the acylphosphatase family
dqs_RS16485	COG1368	sulfuric ester hydrolase activity
dqs_RS16510	COG0281	malic enzyme
dqs_RS16510	COG0280	phosphate acetyltransferase
dqs_RS16515	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
dqs_RS16520	COG0210	DNA helicase
dqs_RS16530	COG0495	leucyl-tRNA aminoacylation
dqs_RS16540	COG1466	dna polymerase III delta subunit
dqs_RS16545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
dqs_RS16550	COG4974	Belongs to the 'phage' integrase family
dqs_RS16555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
dqs_RS16570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
dqs_RS16575	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
dqs_RS16580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
dqs_RS16615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
dqs_RS16650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
dqs_RS16655	COG2204	response regulator
dqs_RS16670	COG0071	Belongs to the small heat shock protein (HSP20) family
dqs_RS16675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
dqs_RS16685	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_RS16730	COG2755	lipolytic protein G-D-S-L family
dqs_RS16730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
dqs_RS16750	COG1216	Glycosyl transferase, family 2
dqs_RS16760	COG0438	transferase activity, transferring glycosyl groups
dqs_RS16765	COG0438	transferase activity, transferring glycosyl groups
dqs_RS16795	COG0297	glycogen (starch) synthase activity
dqs_RS16810	COG0367	asparagine synthase
dqs_RS16820	COG0367	asparagine synthase
dqs_RS16825	COG0438	transferase activity, transferring glycosyl groups
dqs_RS16850	COG3409	Peptidoglycan-binding domain 1 protein
dqs_RS16850	COG3267	Type II secretory pathway component ExeA
dqs_RS16860	COG0489	protein tyrosine kinase activity
dqs_RS16885	COG1136	(ABC) transporter
dqs_RS16885	COG0577	efflux transmembrane transporter activity
dqs_RS16895	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_RS16910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
dqs_RS16915	COG1999	signal sequence binding
dqs_RS16920	COG0109	protoheme IX farnesyltransferase activity
dqs_RS16925	COG1612	heme a metabolic process
dqs_RS16955	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
dqs_RS16960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
dqs_RS16970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
dqs_RS16975	COG1283	sodium-dependent phosphate transmembrane transporter activity
dqs_RS16990	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
dqs_RS17000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
dqs_RS17030	COG0604	alcohol dehydrogenase
dqs_RS17045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
dqs_RS17055	COG0134	indole-3-glycerol-phosphate synthase activity
dqs_RS17060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
dqs_RS17075	COG0546	phosphoglycolate phosphatase activity
dqs_RS17080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
dqs_RS17085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_RS17090	COG1234	tRNA 3'-trailer cleavage
dqs_RS17100	COG0631	protein serine/threonine phosphatase activity
dqs_RS17105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
dqs_RS17110	COG0045	succinate-CoA ligase (ADP-forming) activity
dqs_RS17125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
dqs_RS17135	COG0805	protein transport
dqs_RS17140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
dqs_RS17145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
dqs_RS17150	COG0140	phosphoribosyl-ATP diphosphatase activity
dqs_RS17155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
dqs_RS17160	COG0107	imidazoleglycerol-phosphate synthase activity
dqs_RS17165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
dqs_RS17170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
dqs_RS17175	COG0131	Imidazoleglycerol-phosphate dehydratase
dqs_RS17180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
dqs_RS17185	COG0741	lytic transglycosylase activity
dqs_RS17195	COG3119	arylsulfatase activity
dqs_RS17205	COG1131	(ABC) transporter
dqs_RS17240	COG0436	Aminotransferase
dqs_RS17245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
dqs_RS17260	COG2084	Dehydrogenase
dqs_RS17265	COG2084	Dehydrogenase
dqs_RS17270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
dqs_RS17290	COG3411	Ferredoxin
dqs_RS17300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
dqs_RS17310	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
dqs_RS17340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
dqs_RS17350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
dqs_RS17365	COG4251	negative regulation of phosphorylation
dqs_RS17375	COG0629	single-stranded DNA binding
dqs_RS17380	COG2814	Major facilitator Superfamily
dqs_RS17395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
dqs_RS17400	COG0203	ribosomal protein L17
dqs_RS17405	COG0202	RNA polymerase activity
dqs_RS17410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
dqs_RS17415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
dqs_RS17420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
dqs_RS17425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
dqs_RS17430	COG0201	protein transport
dqs_RS17435	COG0200	Binds to the 23S rRNA
dqs_RS17440	COG1841	ribosomal large subunit assembly
dqs_RS17445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
dqs_RS17450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
dqs_RS17455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
dqs_RS17460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
dqs_RS17465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
dqs_RS17470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
dqs_RS17475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
dqs_RS17480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
dqs_RS17485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
dqs_RS17490	COG0255	Belongs to the universal ribosomal protein uL29 family
dqs_RS17495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
dqs_RS17500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
dqs_RS17505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
dqs_RS17510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
dqs_RS17515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
dqs_RS17520	COG0089	rRNA binding
dqs_RS17525	COG0088	Forms part of the polypeptide exit tunnel
dqs_RS17530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
dqs_RS17535	COG0051	transcription antitermination factor activity, RNA binding
dqs_RS17540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
dqs_RS17545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
dqs_RS17550	COG0049	tRNA binding
dqs_RS17555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
dqs_RS17560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
dqs_RS17565	COG0085	RNA polymerase activity
dqs_RS17570	COG0222	ribosome binding
dqs_RS17575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
dqs_RS17580	COG0081	regulation of translation
dqs_RS17585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
dqs_RS17595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
dqs_RS17605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
dqs_RS17625	COG0277	FAD linked oxidase domain protein
dqs_RS17645	COG2197	response regulator
dqs_RS17655	COG0784	Response regulator, receiver
dqs_RS17655	COG2198	Histidine kinase
dqs_RS17655	COG2205	protein histidine kinase activity
dqs_RS17665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
dqs_RS17690	COG0559	Belongs to the binding-protein-dependent transport system permease family
dqs_RS17700	COG1022	Amp-dependent synthetase and ligase
dqs_RS17710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
dqs_RS17715	COG0352	thiamine-phosphate diphosphorylase activity
dqs_RS17745	COG0840	transmembrane signaling receptor activity
dqs_RS17755	COG0415	Belongs to the DNA photolyase family
dqs_RS17760	COG1678	Uncharacterized ACR, COG1678
dqs_RS17765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
dqs_RS17770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
dqs_RS17775	COG0540	Belongs to the ATCase OTCase family
dqs_RS17785	COG1872	DUF167
dqs_RS17790	COG0762	integral membrane protein
dqs_RS17840	COG0840	transmembrane signaling receptor activity
dqs_RS17840	COG3290	protein histidine kinase activity
dqs_RS17845	COG0840	transmembrane signaling receptor activity
dqs_RS17870	COG0437	4 iron, 4 sulfur cluster binding
dqs_RS17875	COG0243	molybdopterin cofactor binding
dqs_RS17875	COG3383	formate dehydrogenase (NAD+) activity
dqs_RS17910	COG0746	molybdenum cofactor guanylyltransferase activity
dqs_RS17920	COG1763	Mo-molybdopterin cofactor biosynthetic process
dqs_RS17925	COG3852	Histidine kinase
dqs_RS17935	COG1981	membrane
dqs_RS17950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
dqs_RS17955	COG5002	protein histidine kinase activity
dqs_RS17965	COG4654	Cytochrome c, class I
dqs_RS17970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
dqs_RS17975	COG0830	nickel cation binding
dqs_RS17980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
dqs_RS17985	COG0804	urea catabolic process
dqs_RS17990	COG0832	Belongs to the urease beta subunit family
dqs_RS18000	COG0831	urea catabolic process
dqs_RS18005	COG0829	nickel cation binding
dqs_RS18010	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
dqs_RS18010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
dqs_RS18015	COG1368	sulfuric ester hydrolase activity
dqs_RS18025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_RS18030	COG1116	anion transmembrane transporter activity
dqs_RS18035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_RS18040	COG1733	regulation of RNA biosynthetic process
dqs_RS18050	COG1492	cobalamin metabolic process
dqs_RS18075	COG0513	Belongs to the DEAD box helicase family
dqs_RS18080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_RS18085	COG0778	Nitroreductase
dqs_RS18100	COG5001	Diguanylate cyclase
dqs_RS18100	COG5002	protein histidine kinase activity
dqs_RS18125	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
dqs_RS18155	COG3411	Ferredoxin
dqs_RS18165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
dqs_RS18170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_RS18175	COG0625	glutathione transferase activity
dqs_RS18185	COG0427	acetyl-CoA hydrolase
dqs_RS18195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
dqs_RS18210	COG0688	phosphatidylethanolamine metabolic process
dqs_RS18215	COG1797	cobyrinic acid a,c-diamide synthase activity
dqs_RS18220	COG1648	precorrin-2 dehydrogenase activity
dqs_RS18220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
dqs_RS18230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
dqs_RS18235	COG4139	cobalamin transport
dqs_RS18240	COG4206	TonB-dependent receptor
dqs_RS18255	COG0501	Belongs to the peptidase M48B family
dqs_RS18265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
dqs_RS18270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
dqs_RS18280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
dqs_RS18280	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
dqs_RS18285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_RS18290	COG0859	PFAM glycosyl transferase family 9
dqs_RS18300	COG0438	transferase activity, transferring glycosyl groups
dqs_RS18325	COG1132	(ABC) transporter
dqs_RS18355	COG0438	transferase activity, transferring glycosyl groups
dqs_RS18360	COG2192	nodulation
dqs_RS18365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
dqs_RS18365	COG2755	lipolytic protein G-D-S-L family
dqs_RS18375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
dqs_RS18395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_RS18440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
dqs_RS18460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_RS18485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
dqs_RS18500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
dqs_RS18505	COG0799	negative regulation of ribosome biogenesis
dqs_RS18510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
dqs_RS18515	COG0242	peptide deformylase activity
dqs_RS18520	COG0424	maF-like protein
dqs_RS18525	COG1530	ribonuclease E activity
dqs_RS18555	COG0583	DNA-binding transcription factor activity
dqs_RS18565	COG2818	Glycosylase
dqs_RS18575	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
dqs_RS18580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
dqs_RS18590	COG0443	Heat shock 70 kDa protein
dqs_RS18595	COG0741	lytic transglycosylase activity
dqs_RS18615	COG0583	DNA-binding transcription factor activity
dqs_RS18620	COG2814	Major facilitator Superfamily
dqs_RS18630	COG1132	(ABC) transporter
dqs_RS18655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
dqs_RS18680	COG0067	glutamate synthase
dqs_RS18680	COG0069	glutamate synthase activity
dqs_RS18680	COG0070	glutamate synthase
dqs_RS18685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
dqs_RS18690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
dqs_RS18695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
dqs_RS18730	COG1965	Belongs to the frataxin family
dqs_RS18755	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
dqs_RS18760	COG0284	orotidine-5'-phosphate decarboxylase activity
dqs_RS18770	COG0243	molybdopterin cofactor binding
dqs_RS18780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
dqs_RS18785	COG0708	Exodeoxyribonuclease III
dqs_RS18800	COG4575	ribosome binding
dqs_RS18815	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
dqs_RS18835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS18845	COG0625	glutathione transferase activity
dqs_RS18850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_RS18910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
dqs_RS18920	COG0840	transmembrane signaling receptor activity
dqs_RS18940	COG0180	Tryptophanyl-tRNA synthetase
dqs_RS18960	COG3876	Protein conserved in bacteria
dqs_RS18965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_RS18975	COG2226	methyltransferase
dqs_RS18980	COG2020	methyltransferase activity
dqs_RS18990	COG2169	Transcriptional regulator
dqs_RS18990	COG1917	Cupin 2, conserved barrel domain protein
dqs_RS18995	COG4106	trans-aconitate 2-methyltransferase activity
dqs_RS19010	COG0456	acetyltransferase
dqs_RS19025	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
dqs_RS19030	COG2816	NAD+ diphosphatase activity
dqs_RS19120	COG2814	Major facilitator Superfamily
dqs_RS19140	COG0347	Belongs to the P(II) protein family
dqs_RS19145	COG0004	ammonium transporteR
dqs_RS19150	COG3047	cAMP biosynthetic process
dqs_RS19155	COG0788	formyltetrahydrofolate deformylase activity
dqs_RS19170	COG0488	(ABC) transporter
dqs_RS19195	COG1335	isochorismatase
dqs_RS19210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
dqs_RS19210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
dqs_RS19210	COG0506	proline dehydrogenase activity
dqs_RS19220	COG0189	ligase activity
dqs_RS19240	COG2703	oxygen carrier activity
dqs_RS19280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
dqs_RS19285	COG0753	catalase activity
dqs_RS19290	COG0402	S-adenosylhomocysteine deaminase activity
dqs_RS19295	COG1652	LysM domain
dqs_RS19315	COG0515	serine threonine protein kinase
dqs_RS19315	COG2815	serine threonine protein kinase
dqs_RS19320	COG0826	peptidase U32
dqs_RS19330	COG3706	GGDEF domain
dqs_RS19340	COG0488	(ABC) transporter
dqs_RS19345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
dqs_RS19345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
dqs_RS19350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
dqs_RS19355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
dqs_RS19375	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
dqs_RS19380	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
dqs_RS19420	COG1773	rubredoxin
dqs_RS19440	COG0375	protein maturation
dqs_RS19450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
dqs_RS19460	COG0409	Hydrogenase expression formation protein
dqs_RS19465	COG0309	Hydrogenase expression formation protein (HypE)
dqs_RS19470	COG2204	response regulator
dqs_RS19500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_RS19505	COG1194	a g-specific adenine glycosylase
dqs_RS19555	COG1970	mechanosensitive ion channel activity
dqs_RS19560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_RS19575	COG3842	ATPase activity
dqs_RS19585	COG1349	DNA-binding transcription factor activity
dqs_RS19595	COG4302	ethanolamine ammonia-lyase activity
dqs_RS19635	COG3585	molybdate ion transport
dqs_RS19635	COG2005	Transcriptional regulator
dqs_RS19645	COG2982	Protein involved in outer membrane biogenesis
dqs_RS19655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
dqs_RS19660	COG1074	ATP-dependent DNA helicase activity
dqs_RS19665	COG4206	TonB-dependent receptor
dqs_RS19675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
dqs_RS19680	COG1785	Belongs to the alkaline phosphatase family
dqs_RS19690	COG1024	Enoyl-CoA hydratase
dqs_RS19690	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_RS19695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
dqs_RS19700	COG0583	DNA-binding transcription factor activity
dqs_RS19705	COG0473	3-isopropylmalate dehydrogenase activity
dqs_RS19710	COG3530	Putative quorum-sensing-regulated virulence factor
dqs_RS19715	COG2095	MarC family integral membrane protein
dqs_RS19740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
dqs_RS19745	COG0022	dehydrogenase e1 component
dqs_RS19760	COG0095	Lipoate-protein ligase
dqs_RS19780	COG3284	Transcriptional regulator
dqs_RS19830	COG0631	protein serine/threonine phosphatase activity
dqs_RS19950	COG0840	transmembrane signaling receptor activity
dqs_RS19960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
dqs_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_RS19980	COG0475	glutathione-regulated potassium exporter activity
dqs_RS19985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
dqs_RS20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_RS20030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
dqs_RS20040	COG4235	cytochrome complex assembly
dqs_RS20045	COG3088	subunit of a heme lyase
dqs_RS20050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_RS20060	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
dqs_RS20075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
dqs_RS20080	COG4133	protoheme IX ABC transporter activity
dqs_RS20085	COG0840	transmembrane signaling receptor activity
dqs_RS20090	COG3005	denitrification pathway
dqs_RS20095	COG3043	anaerobic respiration
dqs_RS20100	COG0348	domain, Protein
dqs_RS20105	COG0437	4 iron, 4 sulfur cluster binding
dqs_RS20110	COG0243	molybdopterin cofactor binding
dqs_RS20120	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS20120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_RS20125	COG0784	Response regulator, receiver
dqs_RS20125	COG5002	protein histidine kinase activity
dqs_RS20125	COG2205	protein histidine kinase activity
dqs_RS20130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_RS20130	COG2205	protein histidine kinase activity
dqs_RS20135	COG2205	protein histidine kinase activity
dqs_RS20135	COG4999	Histidine kinase
dqs_RS20135	COG3850	Histidine kinase
dqs_RS20135	COG3437	response regulator, receiver
dqs_RS20140	COG5002	protein histidine kinase activity
dqs_RS20140	COG2176	DNA-directed DNA polymerase activity
dqs_RS20145	COG2226	methyltransferase
dqs_RS20155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
dqs_RS20160	COG1758	RNA polymerase activity
dqs_RS20165	COG0194	GDP metabolic process
dqs_RS20185	COG0587	DNA-directed DNA polymerase activity
dqs_RS20195	COG0789	Transcriptional regulator
dqs_RS20200	COG1561	YicC-like family, N-terminal region
dqs_RS20205	COG3266	domain, Protein
dqs_RS20205	COG0515	serine threonine protein kinase
dqs_RS20210	COG0631	protein serine/threonine phosphatase activity
dqs_RS20215	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
dqs_RS20220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
dqs_RS20225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
dqs_RS20235	COG0616	signal peptide processing
dqs_RS20240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
dqs_RS20245	COG2022	thiamine diphosphate biosynthetic process
dqs_RS20255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
dqs_RS20260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
dqs_RS20260	COG2813	Specifically methylates the guanine in position
dqs_RS20275	COG2223	nitrite transmembrane transporter activity
dqs_RS20285	COG0288	reversible hydration of carbon dioxide
dqs_RS20290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
dqs_RS20295	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
dqs_RS20300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
dqs_RS20305	COG0569	domain protein
dqs_RS20310	COG2204	response regulator
dqs_RS20315	COG5000	phosphorelay sensor kinase activity
dqs_RS20330	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
dqs_RS20335	COG0730	response to heat
dqs_RS20340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
dqs_RS20345	COG0706	membrane insertase activity
dqs_RS20350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
dqs_RS20355	COG0594	ribonuclease P activity
dqs_RS20405	COG3423	Transcriptional regulator
dqs_RS20420	COG4256	Hemin uptake protein
dqs_RS20455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_RS20470	COG1534	Rna-binding protein
dqs_RS20485	COG3852	Histidine kinase
dqs_RS20530	COG1116	anion transmembrane transporter activity
dqs_RS20555	COG5039	Polysaccharide pyruvyl transferase
dqs_RS20560	COG1215	transferase activity, transferring glycosyl groups
dqs_RS20565	COG1215	transferase activity, transferring glycosyl groups
dqs_RS20570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
dqs_RS20575	COG4269	membrane
dqs_RS20600	COG0230	Belongs to the bacterial ribosomal protein bL34 family
dqs_RS20915	COG2840	Smr protein MutS2
dqs_RS20935	COG5002	protein histidine kinase activity
dqs_RS20935	COG5001	Diguanylate cyclase
dqs_RS20935	COG3447	MASE1 domain protein