locus-tag	class	description
AZO_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZO_RS00020	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZO_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS00060	COG0583	DNA-binding transcription factor activity
AZO_RS00065	COG0564	pseudouridine synthase activity
AZO_RS00090	COG0693	protein deglycase activity
AZO_RS00115	COG3608	succinylglutamate desuccinylase aspartoacylase
AZO_RS00115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZO_RS00125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS00130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZO_RS00135	COG1216	Glycosyl transferase, family 2
AZO_RS00145	COG1253	flavin adenine dinucleotide binding
AZO_RS00150	COG0583	DNA-binding transcription factor activity
AZO_RS00155	COG0477	Major facilitator Superfamily
AZO_RS00195	COG1944	ATP diphosphatase activity
AZO_RS00215	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZO_RS00220	COG1984	allophanate hydrolase subunit 2
AZO_RS00225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZO_RS00230	COG0596	Alpha beta hydrolase
AZO_RS00235	COG4676	Protein conserved in bacteria
AZO_RS00240	COG4676	Protein conserved in bacteria
AZO_RS00245	COG5445	Predicted secreted protein (DUF2300)
AZO_RS00275	COG1136	(ABC) transporter
AZO_RS00280	COG0577	efflux transmembrane transporter activity
AZO_RS00300	COG2373	Large extracellular alpha-helical protein
AZO_RS00310	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AZO_RS00325	COG0628	permease
AZO_RS00335	COG1024	Enoyl-CoA hydratase
AZO_RS00365	COG4191	Histidine kinase
AZO_RS00375	COG2304	oxidoreductase activity
AZO_RS00380	COG1595	DNA-templated transcription, initiation
AZO_RS00400	COG1690	Belongs to the RtcB family
AZO_RS00405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZO_RS00415	COG2974	May be involved in recombination
AZO_RS00425	COG1187	pseudouridine synthase activity
AZO_RS00435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZO_RS00445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZO_RS00455	COG3909	cytochrome
AZO_RS00460	COG0840	transmembrane signaling receptor activity
AZO_RS00465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZO_RS00470	COG4206	TonB-dependent receptor
AZO_RS00480	COG0551	DNA topoisomerase type I activity
AZO_RS00480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZO_RS00485	COG2922	Belongs to the Smg family
AZO_RS00490	COG0758	DNA mediated transformation
AZO_RS00500	COG0242	peptide deformylase activity
AZO_RS00505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZO_RS00515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZO_RS00520	COG1305	Transglutaminase-like
AZO_RS00550	COG1490	D-aminoacyl-tRNA deacylase activity
AZO_RS00555	COG1741	Belongs to the pirin family
AZO_RS00565	COG0583	DNA-binding transcription factor activity
AZO_RS00570	COG0625	glutathione transferase activity
AZO_RS00580	COG2030	dehydratase
AZO_RS00585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZO_RS00615	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZO_RS00650	COG0840	transmembrane signaling receptor activity
AZO_RS00655	COG0840	transmembrane signaling receptor activity
AZO_RS00660	COG1942	4-Oxalocrotonate Tautomerase
AZO_RS00665	COG0583	DNA-binding transcription factor activity
AZO_RS00710	COG0445	tRNA wobble uridine modification
AZO_RS00715	COG0357	Ribosomal RNA small subunit methyltransferase G
AZO_RS00720	COG1192	Involved in chromosome partitioning
AZO_RS00735	COG1475	DNA binding
AZO_RS00745	COG0477	Major facilitator Superfamily
AZO_RS00760	COG0640	Transcriptional regulator
AZO_RS00770	COG0356	it plays a direct role in the translocation of protons across the membrane
AZO_RS00780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZO_RS00785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZO_RS00790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZO_RS00795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZO_RS00800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZO_RS00805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZO_RS00815	COG2226	methyltransferase
AZO_RS00825	COG0745	RESPONSE REGULATOR receiver
AZO_RS00845	COG0121	glutamine amidotransferase
AZO_RS00855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZO_RS00865	COG0154	amidase activity
AZO_RS00870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZO_RS00875	COG1077	Cell shape determining protein MreB Mrl
AZO_RS00890	COG0768	penicillin binding
AZO_RS00895	COG0772	Belongs to the SEDS family
AZO_RS00905	COG1686	Belongs to the peptidase S11 family
AZO_RS00915	COG2921	Belongs to the UPF0250 family
AZO_RS00920	COG0321	lipoyl(octanoyl) transferase activity
AZO_RS00925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZO_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS00990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZO_RS01020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZO_RS01020	COG0512	Glutamine amidotransferase of anthranilate synthase
AZO_RS01030	COG0419	ATPase involved in DNA repair
AZO_RS01055	COG1473	amidohydrolase
AZO_RS01060	COG2207	Transcriptional regulator
AZO_RS01090	COG1522	sequence-specific DNA binding
AZO_RS01105	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS01115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZO_RS01125	COG0601	transmembrane transport
AZO_RS01130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZO_RS01210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AZO_RS01215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZO_RS01230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZO_RS01255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZO_RS01265	COG2193	ferroxidase activity
AZO_RS01320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZO_RS01335	COG0642	Histidine kinase
AZO_RS01385	COG1595	DNA-templated transcription, initiation
AZO_RS01425	COG1360	Flagellar Motor Protein
AZO_RS01445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZO_RS01465	COG1131	(ABC) transporter
AZO_RS01480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZO_RS01500	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZO_RS01515	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS01520	COG1024	Enoyl-CoA hydratase
AZO_RS01525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS01530	COG2050	protein possibly involved in aromatic compounds catabolism
AZO_RS01540	COG3396	Phenylacetate-CoA oxygenase
AZO_RS01545	COG3460	Phenylacetate-CoA oxygenase
AZO_RS01550	COG3396	Phenylacetate-CoA oxygenase
AZO_RS01555	COG2151	metal-sulfur cluster biosynthetic enzyme
AZO_RS01560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZO_RS01570	COG0183	Belongs to the thiolase family
AZO_RS01600	COG0513	Belongs to the DEAD box helicase family
AZO_RS01605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZO_RS01610	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZO_RS01625	COG4232	protein-disulfide reductase activity
AZO_RS01630	COG1324	tolerance protein
AZO_RS01635	COG2070	2-Nitropropane dioxygenase
AZO_RS01645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZO_RS01655	COG1309	transcriptional regulator
AZO_RS01670	COG0583	DNA-binding transcription factor activity
AZO_RS01695	COG1716	ATPase activity
AZO_RS01695	COG5001	Diguanylate cyclase
AZO_RS01700	COG3706	GGDEF domain
AZO_RS01710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZO_RS01735	COG1192	Involved in chromosome partitioning
AZO_RS01755	COG0025	NhaP-type Na H and K H
AZO_RS01765	COG0546	phosphoglycolate phosphatase activity
AZO_RS01765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZO_RS01770	COG2076	Multidrug Resistance protein
AZO_RS01815	COG1131	(ABC) transporter
AZO_RS01820	COG0625	glutathione transferase activity
AZO_RS01845	COG1045	serine acetyltransferase
AZO_RS01855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZO_RS01860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZO_RS01865	COG2119	membrane
AZO_RS01875	COG3154	lipid carrier protein
AZO_RS01880	COG0826	peptidase U32
AZO_RS01885	COG0826	peptidase U32
AZO_RS01890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZO_RS01895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZO_RS01900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZO_RS01915	COG0018	arginyl-trna synthetase
AZO_RS01925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZO_RS01930	COG0300	oxidoreductase activity
AZO_RS01960	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZO_RS01980	COG0183	Belongs to the thiolase family
AZO_RS01985	COG1960	acyl-CoA dehydrogenase activity
AZO_RS02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZO_RS02010	COG1660	Displays ATPase and GTPase activities
AZO_RS02025	COG2201	protein-glutamate methylesterase activity
AZO_RS02035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZO_RS02040	COG0835	chemotaxis
AZO_RS02045	COG0840	transmembrane signaling receptor activity
AZO_RS02050	COG0840	transmembrane signaling receptor activity
AZO_RS02055	COG0643	Histidine kinase
AZO_RS02055	COG2198	Histidine kinase
AZO_RS02070	COG0745	RESPONSE REGULATOR receiver
AZO_RS02085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZO_RS02090	COG0602	queuosine metabolic process
AZO_RS02100	COG2885	chlorophyll binding
AZO_RS02105	COG0823	Involved in the tonB-independent uptake of proteins
AZO_RS02115	COG0848	biopolymer transport protein
AZO_RS02120	COG0811	peptide transport
AZO_RS02125	COG0824	Thioesterase
AZO_RS02135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZO_RS02140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZO_RS02150	COG5001	Diguanylate cyclase
AZO_RS02150	COG3300	MHYT domain
AZO_RS02155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZO_RS02160	COG2895	sulfate adenylyltransferase (ATP) activity
AZO_RS02165	COG0175	sulfate reduction
AZO_RS02170	COG0175	sulfate reduction
AZO_RS02185	COG0730	response to heat
AZO_RS02190	COG0583	DNA-binding transcription factor activity
AZO_RS02215	COG1126	abc transporter atp-binding protein
AZO_RS02220	COG0765	amino acid transport
AZO_RS02225	COG0765	amino acid transport
AZO_RS02230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZO_RS02240	COG1793	dna ligase
AZO_RS02240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZO_RS02245	COG1201	RNA secondary structure unwinding
AZO_RS02270	COG5001	Diguanylate cyclase
AZO_RS02280	COG3634	alkyl hydroperoxide reductase activity
AZO_RS02285	COG5265	(ABC) transporter
AZO_RS02295	COG0523	cobalamin synthesis protein
AZO_RS02305	COG0745	RESPONSE REGULATOR receiver
AZO_RS02310	COG5002	protein histidine kinase activity
AZO_RS02315	COG0004	ammonium transporteR
AZO_RS02335	COG1960	acyl-CoA dehydrogenase activity
AZO_RS02345	COG1024	Enoyl-CoA hydratase
AZO_RS02345	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS02355	COG2067	long-chain fatty acid transport protein
AZO_RS02360	COG1024	Enoyl-CoA hydratase
AZO_RS02360	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS02365	COG0183	Belongs to the thiolase family
AZO_RS02370	COG1024	Enoyl-CoA hydratase
AZO_RS02400	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZO_RS02410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZO_RS02415	COG3161	chorismate lyase activity
AZO_RS02420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZO_RS02430	COG0251	oxidation-reduction process
AZO_RS02435	COG1238	metal cluster binding
AZO_RS02450	COG0037	tRNA processing
AZO_RS02475	COG0625	glutathione transferase activity
AZO_RS02485	COG0617	tRNA 3'-terminal CCA addition
AZO_RS02500	COG0741	lytic transglycosylase activity
AZO_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZO_RS02520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZO_RS02525	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZO_RS02535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZO_RS02540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZO_RS02550	COG2137	regulation of response to DNA damage stimulus
AZO_RS02555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZO_RS02560	COG1546	Belongs to the CinA family
AZO_RS02565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZO_RS02570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AZO_RS02575	COG2914	Belongs to the UPF0125 (RnfH) family
AZO_RS02595	COG4656	Part of a membrane complex involved in electron transport
AZO_RS02600	COG2878	Part of a membrane complex involved in electron transport
AZO_RS02605	COG4657	Part of a membrane complex involved in electron transport
AZO_RS02630	COG2032	superoxide dismutase activity
AZO_RS02640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZO_RS02650	COG0426	domain, Protein
AZO_RS02655	COG0633	Ferredoxin
AZO_RS02685	COG3647	Membrane
AZO_RS02710	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZO_RS02730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZO_RS02745	COG0840	transmembrane signaling receptor activity
AZO_RS02880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZO_RS02885	COG0393	Putative heavy-metal-binding
AZO_RS02895	COG0217	transcriptional regulatory protein
AZO_RS02905	COG0433	COG0433 Predicted ATPase
AZO_RS02910	COG0583	DNA-binding transcription factor activity
AZO_RS02915	COG2814	Major facilitator Superfamily
AZO_RS02920	COG0697	spore germination
AZO_RS02925	COG0840	transmembrane signaling receptor activity
AZO_RS02930	COG2814	Major facilitator Superfamily
AZO_RS02935	COG2814	Major facilitator Superfamily
AZO_RS02945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZO_RS02950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZO_RS02960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZO_RS02970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZO_RS02990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZO_RS03000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AZO_RS03010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZO_RS03025	COG2255	four-way junction helicase activity
AZO_RS03030	COG0632	four-way junction helicase activity
AZO_RS03055	COG4774	siderophore transport
AZO_RS03060	COG3128	pkhd-type hydroxylase
AZO_RS03065	COG1304	FMN binding
AZO_RS03075	COG0577	efflux transmembrane transporter activity
AZO_RS03075	COG1136	(ABC) transporter
AZO_RS03080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZO_RS03125	COG5001	Diguanylate cyclase
AZO_RS03145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZO_RS03150	COG3132	Protein of unknown function, DUF480
AZO_RS03170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZO_RS03175	COG0129	dihydroxy-acid dehydratase activity
AZO_RS03185	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AZO_RS03205	COG0247	lactate metabolic process
AZO_RS03225	COG1121	(ABC) transporter
AZO_RS03235	COG0735	belongs to the Fur family
AZO_RS03245	COG2274	protein secretion by the type I secretion system
AZO_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZO_RS03275	COG3706	GGDEF domain
AZO_RS03275	COG4251	negative regulation of phosphorylation
AZO_RS03275	COG5001	Diguanylate cyclase
AZO_RS03275	COG2203	Gaf domain
AZO_RS03285	COG1538	Outer membrane efflux protein
AZO_RS03315	COG1132	(ABC) transporter
AZO_RS03320	COG1451	nucleotide metabolic process
AZO_RS03330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZO_RS03335	COG2267	carboxylic ester hydrolase activity
AZO_RS03340	COG0671	phosphoesterase, PA-phosphatase related
AZO_RS03340	COG2453	phosphatase
AZO_RS03350	COG0204	Acyl-transferase
AZO_RS03355	COG4589	Belongs to the CDS family
AZO_RS03360	COG3005	denitrification pathway
AZO_RS03365	COG3043	anaerobic respiration
AZO_RS03370	COG0243	molybdopterin cofactor binding
AZO_RS03380	COG4459	periplasmic nitrate reductase
AZO_RS03410	COG0583	DNA-binding transcription factor activity
AZO_RS03415	COG1024	Enoyl-CoA hydratase
AZO_RS03420	COG3162	membrane
AZO_RS03425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZO_RS03430	COG1253	flavin adenine dinucleotide binding
AZO_RS03435	COG1802	Transcriptional regulator
AZO_RS03440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZO_RS03440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZO_RS03445	COG1703	isobutyryl-CoA mutase activity
AZO_RS03450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZO_RS03455	COG4770	biotin carboxylase activity
AZO_RS03470	COG2321	neutral zinc metallopeptidase
AZO_RS03495	COG1703	isobutyryl-CoA mutase activity
AZO_RS03495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZO_RS03495	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZO_RS03510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AZO_RS03520	COG4452	Inner membrane protein CreD
AZO_RS03525	COG2205	protein histidine kinase activity
AZO_RS03530	COG0745	RESPONSE REGULATOR receiver
AZO_RS03535	COG2239	Acts as a magnesium transporter
AZO_RS03540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZO_RS03545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZO_RS03555	COG0557	exoribonuclease II activity
AZO_RS03560	COG2226	methyltransferase
AZO_RS03565	COG3150	esterase
AZO_RS03570	COG1968	undecaprenyl-diphosphatase activity
AZO_RS03590	COG1643	Atp-dependent helicase
AZO_RS03600	COG0360	Binds together with S18 to 16S ribosomal RNA
AZO_RS03605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZO_RS03610	COG0359	binds to the 23S rRNA
AZO_RS03615	COG0305	Participates in initiation and elongation during chromosome replication
AZO_RS03645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZO_RS03650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZO_RS03655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZO_RS03665	COG0494	nUDIX hydrolase
AZO_RS03670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZO_RS03675	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AZO_RS03680	COG0237	dephospho-CoA kinase activity
AZO_RS03690	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZO_RS03695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZO_RS03695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZO_RS03705	COG3852	Histidine kinase
AZO_RS03715	COG0174	glutamine synthetase
AZO_RS03730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZO_RS03735	COG3568	Endonuclease Exonuclease Phosphatase
AZO_RS03740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZO_RS03745	COG1832	CoA-binding protein
AZO_RS03750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZO_RS03775	COG0463	Glycosyl transferase, family 2
AZO_RS03790	COG0012	GTP binding
AZO_RS03795	COG0193	aminoacyl-tRNA hydrolase activity
AZO_RS03800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZO_RS03805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZO_RS03815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZO_RS03820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AZO_RS03830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZO_RS03835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZO_RS03840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZO_RS03845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZO_RS03850	COG0742	ribosomal rna small subunit methyltransferase
AZO_RS03855	COG0612	Peptidase, M16
AZO_RS03860	COG0612	Peptidase, M16
AZO_RS03870	COG2884	Cell division ATP-binding protein ftsE
AZO_RS03875	COG2177	Part of the ABC transporter FtsEX involved in
AZO_RS03885	COG3634	alkyl hydroperoxide reductase activity
AZO_RS03895	COG0328	RNA-DNA hybrid ribonuclease activity
AZO_RS03905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZO_RS03925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZO_RS03930	COG1702	phosphate starvation-inducible protein PhoH
AZO_RS03935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZO_RS03940	COG4535	Mg2 and Co2 transporter CorC
AZO_RS03945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZO_RS03960	COG0752	glycyl-tRNA synthetase alpha subunit
AZO_RS03965	COG0751	glycine-tRNA ligase activity
AZO_RS03970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZO_RS03975	COG0204	Acyl-transferase
AZO_RS03985	COG1024	Enoyl-CoA hydratase
AZO_RS03990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AZO_RS04000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AZO_RS04050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZO_RS04060	COG1450	Type ii and iii secretion system protein
AZO_RS04065	COG1127	ABC transporter
AZO_RS04070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZO_RS04075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZO_RS04080	COG2853	Lipoprotein
AZO_RS04095	COG1131	(ABC) transporter
AZO_RS04100	COG0842	Transport permease protein
AZO_RS04110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZO_RS04115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZO_RS04120	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZO_RS04125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZO_RS04130	COG0436	Aminotransferase
AZO_RS04135	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AZO_RS04140	COG0280	phosphate acetyltransferase
AZO_RS04140	COG0281	malic enzyme
AZO_RS04150	COG1686	Belongs to the peptidase S11 family
AZO_RS04165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZO_RS04180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZO_RS04195	COG1136	(ABC) transporter
AZO_RS04195	COG0577	efflux transmembrane transporter activity
AZO_RS04200	COG0577	efflux transmembrane transporter activity
AZO_RS04200	COG1136	(ABC) transporter
AZO_RS04205	COG1136	(ABC) transporter
AZO_RS04205	COG0577	efflux transmembrane transporter activity
AZO_RS04215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZO_RS04220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZO_RS04225	COG2885	chlorophyll binding
AZO_RS04230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZO_RS04235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZO_RS04240	COG0351	phosphomethylpyrimidine kinase
AZO_RS04275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZO_RS04280	COG0425	Belongs to the sulfur carrier protein TusA family
AZO_RS04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZO_RS04300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AZO_RS04320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZO_RS04340	COG2264	protein methyltransferase activity
AZO_RS04345	COG0439	Biotin carboxylase
AZO_RS04350	COG0511	ligase activity, forming carbon-carbon bonds
AZO_RS04355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZO_RS04360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZO_RS04370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZO_RS04375	COG2823	Periplasmic or secreted lipoprotein
AZO_RS04380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZO_RS04385	COG0792	nuclease activity
AZO_RS04395	COG0418	dihydroorotase activity
AZO_RS04405	COG2001	Belongs to the MraZ family
AZO_RS04410	COG0275	rRNA processing
AZO_RS04425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZO_RS04430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZO_RS04435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZO_RS04440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZO_RS04445	COG0772	Belongs to the SEDS family
AZO_RS04450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZO_RS04455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZO_RS04460	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZO_RS04465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZO_RS04475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZO_RS04480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AZO_RS04495	COG0653	protein targeting
AZO_RS04505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZO_RS04510	COG0631	protein serine/threonine phosphatase activity
AZO_RS04530	COG2967	ApaG domain
AZO_RS04545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZO_RS04550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZO_RS04555	COG1862	Preprotein translocase
AZO_RS04565	COG0343	queuine tRNA-ribosyltransferase activity
AZO_RS04570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZO_RS04580	COG0583	DNA-binding transcription factor activity
AZO_RS04590	COG0670	Belongs to the BI1 family
AZO_RS04595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZO_RS04595	COG4651	solute:proton antiporter activity
AZO_RS04600	COG1253	flavin adenine dinucleotide binding
AZO_RS04605	COG0861	Integral membrane protein TerC family
AZO_RS04610	COG0825	malonyl-CoA metabolic process
AZO_RS04615	COG0037	tRNA processing
AZO_RS04620	COG4566	intracellular signal transduction
AZO_RS04645	COG0586	Pfam SNARE associated Golgi protein
AZO_RS04650	COG0105	UTP biosynthetic process
AZO_RS04655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZO_RS04670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZO_RS04675	COG0124	histidyl-tRNA synthetase
AZO_RS04685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZO_RS04690	COG1160	GTP binding
AZO_RS04695	COG1923	regulation of RNA biosynthetic process
AZO_RS04700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZO_RS04705	COG0330	HflC and HflK could
AZO_RS04710	COG0330	HflC and HflK could
AZO_RS04715	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AZO_RS04720	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZO_RS04725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZO_RS04740	COG0557	exoribonuclease II activity
AZO_RS04745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZO_RS04750	COG3707	response regulator
AZO_RS04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZO_RS04765	COG1116	anion transmembrane transporter activity
AZO_RS04775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZO_RS04780	COG0243	molybdopterin cofactor binding
AZO_RS04805	COG0551	DNA topoisomerase type I activity
AZO_RS04815	COG0716	FMN binding
AZO_RS04825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZO_RS04830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZO_RS04835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZO_RS04840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZO_RS04845	COG0723	plastoquinol--plastocyanin reductase activity
AZO_RS04850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZO_RS04855	COG2857	Cytochrome c1
AZO_RS04860	COG0625	glutathione transferase activity
AZO_RS04870	COG0438	transferase activity, transferring glycosyl groups
AZO_RS04880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZO_RS04885	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZO_RS04900	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZO_RS04910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZO_RS04915	COG0459	protein refolding
AZO_RS04925	COG0642	Histidine kinase
AZO_RS04930	COG3162	membrane
AZO_RS04950	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZO_RS04955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZO_RS04965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZO_RS04990	COG0515	serine threonine protein kinase
AZO_RS04990	COG2815	serine threonine protein kinase
AZO_RS04995	COG0165	Argininosuccinate lyase
AZO_RS05000	COG3275	phosphorelay sensor kinase activity
AZO_RS05010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZO_RS05015	COG0181	hydroxymethylbilane synthase activity
AZO_RS05025	COG2959	enzyme of heme biosynthesis
AZO_RS05035	COG2186	Transcriptional regulator
AZO_RS05040	COG0277	FAD linked oxidase domain protein
AZO_RS05045	COG0277	FAD linked oxidase domain protein
AZO_RS05050	COG0247	lactate metabolic process
AZO_RS05055	COG0631	protein serine/threonine phosphatase activity
AZO_RS05085	COG0513	Belongs to the DEAD box helicase family
AZO_RS05090	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AZO_RS05095	COG0667	Aldo Keto reductase
AZO_RS05105	COG1653	transport
AZO_RS05110	COG0584	glycerophosphoryl diester phosphodiesterase
AZO_RS05115	COG0142	geranyltranstransferase activity
AZO_RS05125	COG0583	DNA-binding transcription factor activity
AZO_RS05140	COG0564	pseudouridine synthase activity
AZO_RS05155	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZO_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS05175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZO_RS05180	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZO_RS05185	COG0277	FAD linked oxidase domain protein
AZO_RS05220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS05225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZO_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS05250	COG0028	Belongs to the TPP enzyme family
AZO_RS05255	COG0440	acetolactate synthase activity
AZO_RS05260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZO_RS05265	COG2814	Major facilitator Superfamily
AZO_RS05270	COG4783	chaperone-mediated protein folding
AZO_RS05275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZO_RS05280	COG0066	3-isopropylmalate dehydratase activity
AZO_RS05285	COG0473	3-isopropylmalate dehydrogenase activity
AZO_RS05305	COG0101	tRNA pseudouridine synthase activity
AZO_RS05310	COG0135	phosphoribosylanthranilate isomerase activity
AZO_RS05315	COG0133	tryptophan synthase activity
AZO_RS05320	COG0159	tryptophan synthase activity
AZO_RS05325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZO_RS05330	COG0285	dihydrofolate synthase activity
AZO_RS05335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AZO_RS05355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZO_RS05360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZO_RS05365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZO_RS05380	COG0215	cysteine-tRNA ligase activity
AZO_RS05390	COG0484	heat shock protein binding
AZO_RS05395	COG0443	Heat shock 70 kDa protein
AZO_RS05400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZO_RS05410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZO_RS05420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZO_RS05425	COG0287	Prephenate dehydrogenase
AZO_RS05430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZO_RS05440	COG0776	regulation of translation
AZO_RS05450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AZO_RS05475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZO_RS05480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZO_RS05485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZO_RS05490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZO_RS05495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZO_RS05500	COG0072	phenylalanine-tRNA ligase activity
AZO_RS05500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZO_RS05505	COG0776	regulation of translation
AZO_RS05520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AZO_RS05525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZO_RS05535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZO_RS05540	COG2951	lytic endotransglycosylase activity
AZO_RS05555	COG0714	Associated with various cellular activities
AZO_RS05560	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZO_RS05565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZO_RS05570	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AZO_RS05580	COG2850	peptidyl-arginine hydroxylation
AZO_RS05585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZO_RS05610	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZO_RS05630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZO_RS05640	COG1360	Flagellar Motor Protein
AZO_RS05645	COG2703	oxygen carrier activity
AZO_RS05670	COG2860	membrane
AZO_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS05700	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZO_RS05705	COG4638	Rieske (2fe-2S)
AZO_RS05725	COG0411	ABC transporter
AZO_RS05740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZO_RS05750	COG0542	response to heat
AZO_RS05755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZO_RS05760	COG1278	Cold shock
AZO_RS05765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZO_RS05770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZO_RS05775	COG2003	Belongs to the UPF0758 family
AZO_RS05780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZO_RS05785	COG0756	dUTP diphosphatase activity
AZO_RS05795	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZO_RS05815	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AZO_RS05825	COG0538	isocitrate dehydrogenase activity
AZO_RS05835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZO_RS05860	COG1346	cytolysis
AZO_RS05885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZO_RS05890	COG0730	response to heat
AZO_RS05895	COG0583	DNA-binding transcription factor activity
AZO_RS05905	COG3622	Belongs to the hyi family
AZO_RS05925	COG1139	Iron-sulfur cluster binding protein
AZO_RS05935	COG0247	lactate metabolic process
AZO_RS05950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZO_RS05960	COG2116	formate transmembrane transporter activity
AZO_RS05965	COG2815	serine threonine protein kinase
AZO_RS05965	COG0515	serine threonine protein kinase
AZO_RS05975	COG4266	Belongs to the allantoicase family
AZO_RS06005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZO_RS06010	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AZO_RS06020	COG0535	radical SAM domain protein
AZO_RS06045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZO_RS06050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZO_RS06055	COG1469	GTP cyclohydrolase I activity
AZO_RS06060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZO_RS06065	COG0142	geranyltranstransferase activity
AZO_RS06070	COG1722	exodeoxyribonuclease VII activity
AZO_RS06080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZO_RS06085	COG1047	Peptidyl-prolyl cis-trans
AZO_RS06090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZO_RS06095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZO_RS06100	COG0196	riboflavin kinase activity
AZO_RS06110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZO_RS06145	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZO_RS06150	COG1121	(ABC) transporter
AZO_RS06155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZO_RS06155	COG1321	iron dependent repressor
AZO_RS06160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZO_RS06185	COG0459	protein refolding
AZO_RS06195	COG0346	lactoylglutathione lyase activity
AZO_RS06220	COG1294	oxidase, subunit
AZO_RS06235	COG2204	response regulator
AZO_RS06240	COG0723	plastoquinol--plastocyanin reductase activity
AZO_RS06245	COG1132	(ABC) transporter
AZO_RS06255	COG0644	oxidoreductase
AZO_RS06265	COG0641	radical SAM
AZO_RS06280	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZO_RS06285	COG0802	atpase or kinase
AZO_RS06295	COG4948	Mandelate Racemase Muconate Lactonizing
AZO_RS06300	COG0583	DNA-binding transcription factor activity
AZO_RS06315	COG2900	Belongs to the SlyX family
AZO_RS06320	COG0826	peptidase U32
AZO_RS06330	COG2133	pyrroloquinoline quinone binding
AZO_RS06335	COG3300	MHYT domain
AZO_RS06335	COG5001	Diguanylate cyclase
AZO_RS06340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZO_RS06345	COG0515	serine threonine protein kinase
AZO_RS06345	COG2815	serine threonine protein kinase
AZO_RS06360	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZO_RS06370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AZO_RS06375	COG1704	LemA family
AZO_RS06380	COG3360	Dodecin
AZO_RS06395	COG0484	heat shock protein binding
AZO_RS06400	COG1607	acyl-coa hydrolase
AZO_RS06405	COG4628	conserved protein (DUF2132)
AZO_RS06410	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AZO_RS06430	COG1127	ABC transporter
AZO_RS06435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZO_RS06440	COG0488	(ABC) transporter
AZO_RS06445	COG2226	methyltransferase
AZO_RS06450	COG0386	Belongs to the glutathione peroxidase family
AZO_RS06460	COG1858	cytochrome C peroxidase
AZO_RS06470	COG0583	DNA-binding transcription factor activity
AZO_RS06490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZO_RS06490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZO_RS06495	COG0509	glycine decarboxylation via glycine cleavage system
AZO_RS06500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZO_RS06530	COG2223	nitrite transmembrane transporter activity
AZO_RS06535	COG2815	serine threonine protein kinase
AZO_RS06535	COG0515	serine threonine protein kinase
AZO_RS06555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZO_RS06570	COG0312	modulator of DNA gyrase
AZO_RS06650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZO_RS06655	COG2824	Alkylphosphonate utilization operon protein PhnA
AZO_RS06665	COG0390	transport system, permease component
AZO_RS06670	COG3842	ATPase activity
AZO_RS06700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZO_RS06710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZO_RS06720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AZO_RS06725	COG0765	amino acid transport
AZO_RS06730	COG4597	amino acid ABC transporter
AZO_RS06735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZO_RS06740	COG0583	DNA-binding transcription factor activity
AZO_RS06745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZO_RS06750	COG4208	sulfate ABC transporter
AZO_RS06755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AZO_RS06765	COG2951	lytic endotransglycosylase activity
AZO_RS06785	COG3278	Belongs to the heme-copper respiratory oxidase family
AZO_RS06825	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZO_RS06830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZO_RS06835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZO_RS06850	COG2217	Heavy metal translocating P-type atpase
AZO_RS06855	COG2608	mercury ion transmembrane transporter activity
AZO_RS06865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZO_RS06875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZO_RS06875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZO_RS06880	COG0347	Belongs to the P(II) protein family
AZO_RS06885	COG2840	Smr protein MutS2
AZO_RS06890	COG0492	ferredoxin-NADP+ reductase activity
AZO_RS06900	COG1674	ftsk spoiiie
AZO_RS06905	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZO_RS06910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZO_RS06920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZO_RS06925	COG0840	transmembrane signaling receptor activity
AZO_RS06930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZO_RS06935	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZO_RS06940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AZO_RS06955	COG4566	intracellular signal transduction
AZO_RS06960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZO_RS06965	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZO_RS06970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZO_RS06975	COG0009	L-threonylcarbamoyladenylate synthase
AZO_RS06985	COG0505	Belongs to the CarA family
AZO_RS06990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZO_RS06995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZO_RS07010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZO_RS07015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZO_RS07020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZO_RS07025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZO_RS07030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZO_RS07035	COG0573	inorganic phosphate transmembrane transporter activity
AZO_RS07040	COG0581	inorganic phosphate transmembrane transporter activity
AZO_RS07050	COG0149	triose-phosphate isomerase activity
AZO_RS07065	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZO_RS07070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZO_RS07075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZO_RS07080	COG0649	NAD binding
AZO_RS07085	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZO_RS07095	COG1034	ATP synthesis coupled electron transport
AZO_RS07100	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZO_RS07105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZO_RS07115	COG0713	ATP synthesis coupled electron transport
AZO_RS07130	COG1007	ATP synthesis coupled electron transport
AZO_RS07140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZO_RS07145	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AZO_RS07155	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AZO_RS07160	COG3259	Nickel-dependent hydrogenase
AZO_RS07175	COG1230	cation diffusion facilitator family transporter
AZO_RS07190	COG2226	methyltransferase
AZO_RS07190	COG0596	Alpha beta hydrolase
AZO_RS07190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZO_RS07210	COG0326	Molecular chaperone. Has ATPase activity
AZO_RS07225	COG0426	domain, Protein
AZO_RS07225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS07260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZO_RS07265	COG4660	Part of a membrane complex involved in electron transport
AZO_RS07275	COG4658	electron transport chain
AZO_RS07280	COG4656	Part of a membrane complex involved in electron transport
AZO_RS07285	COG2878	Part of a membrane complex involved in electron transport
AZO_RS07325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZO_RS07330	COG1360	Flagellar Motor Protein
AZO_RS07340	COG2198	Histidine kinase
AZO_RS07340	COG0643	Histidine kinase
AZO_RS07350	COG0840	transmembrane signaling receptor activity
AZO_RS07355	COG0840	transmembrane signaling receptor activity
AZO_RS07365	COG2201	protein-glutamate methylesterase activity
AZO_RS07375	COG0784	Response regulator, receiver
AZO_RS07375	COG0835	chemotaxis
AZO_RS07380	COG0835	chemotaxis
AZO_RS07380	COG0784	Response regulator, receiver
AZO_RS07385	COG0745	RESPONSE REGULATOR receiver
AZO_RS07390	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZO_RS07395	COG0784	Response regulator, receiver
AZO_RS07395	COG0643	Histidine kinase
AZO_RS07395	COG2198	Histidine kinase
AZO_RS07405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZO_RS07415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZO_RS07420	COG1570	exodeoxyribonuclease VII activity
AZO_RS07425	COG0811	peptide transport
AZO_RS07430	COG0848	biopolymer transport protein
AZO_RS07435	COG1663	tetraacyldisaccharide 4'-kinase activity
AZO_RS07440	COG2835	tetraacyldisaccharide 4'-kinase activity
AZO_RS07445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZO_RS07450	COG0563	adenylate kinase activity
AZO_RS07460	COG0405	Gamma-glutamyltransferase
AZO_RS07465	COG5002	protein histidine kinase activity
AZO_RS07465	COG5001	Diguanylate cyclase
AZO_RS07470	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZO_RS07480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZO_RS07495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZO_RS07495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AZO_RS07500	COG0737	Belongs to the 5'-nucleotidase family
AZO_RS07500	COG4085	toxin activity
AZO_RS07500	COG1525	nuclease
AZO_RS07515	COG2199	diguanylate cyclase activity
AZO_RS07515	COG2200	EAL domain
AZO_RS07515	COG3287	FIST C domain
AZO_RS07520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZO_RS07530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AZO_RS07550	COG0501	Belongs to the peptidase M48B family
AZO_RS07555	COG1196	nuclear chromosome segregation
AZO_RS07570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZO_RS07605	COG4585	Histidine kinase
AZO_RS07620	COG1032	radical SAM domain protein
AZO_RS07635	COG1136	(ABC) transporter
AZO_RS07650	COG2267	carboxylic ester hydrolase activity
AZO_RS07655	COG2308	Evidence 4 Homologs of previously reported genes of
AZO_RS07670	COG0501	Belongs to the peptidase M48B family
AZO_RS07675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AZO_RS07680	COG0166	Belongs to the GPI family
AZO_RS07690	COG0254	rRNA binding
AZO_RS07710	COG0727	PFAM Uncharacterised protein family (UPF0153)
AZO_RS07715	COG0727	PFAM Uncharacterised protein family (UPF0153)
AZO_RS07745	COG3012	SEC-C Motif Domain Protein
AZO_RS07750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZO_RS07780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZO_RS07785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZO_RS07785	COG0022	dehydrogenase e1 component
AZO_RS07795	COG2814	Major facilitator Superfamily
AZO_RS07800	COG0583	DNA-binding transcription factor activity
AZO_RS07820	COG0039	L-malate dehydrogenase activity
AZO_RS07825	COG2188	Transcriptional regulator
AZO_RS07840	COG1053	succinate dehydrogenase
AZO_RS07845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AZO_RS07850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AZO_RS07855	COG0372	Belongs to the citrate synthase family
AZO_RS07860	COG0567	Dehydrogenase, E1 component
AZO_RS07865	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZO_RS07870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZO_RS07880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZO_RS07885	COG1199	ATP-dependent helicase activity
AZO_RS07890	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZO_RS07895	COG0303	'Molybdopterin
AZO_RS07900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZO_RS07905	COG0314	molybdopterin synthase activity
AZO_RS07915	COG0542	response to heat
AZO_RS07925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZO_RS07935	COG3781	membrane
AZO_RS07940	COG0747	negative chemotaxis
AZO_RS07945	COG0601	transmembrane transport
AZO_RS07950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZO_RS07955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AZO_RS07965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZO_RS07970	COG2867	negative regulation of translational initiation
AZO_RS07975	COG2914	Belongs to the UPF0125 (RnfH) family
AZO_RS07990	COG0519	Catalyzes the synthesis of GMP from XMP
AZO_RS07990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZO_RS07995	COG0583	DNA-binding transcription factor activity
AZO_RS08030	COG1376	ErfK ybiS ycfS ynhG family protein
AZO_RS08055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZO_RS08060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZO_RS08075	COG0084	hydrolase, TatD family'
AZO_RS08095	COG1305	Transglutaminase-like
AZO_RS08100	COG2307	Protein conserved in bacteria
AZO_RS08100	COG2308	Evidence 4 Homologs of previously reported genes of
AZO_RS08110	COG1473	amidohydrolase
AZO_RS08115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AZO_RS08120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZO_RS08130	COG1067	ATP-dependent peptidase activity
AZO_RS08150	COG0556	nucleotide-excision repair
AZO_RS08155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZO_RS08160	COG1530	ribonuclease E activity
AZO_RS08165	COG0564	pseudouridine synthase activity
AZO_RS08170	COG0546	phosphoglycolate phosphatase activity
AZO_RS08180	COG0616	signal peptide processing
AZO_RS08185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZO_RS08190	COG0424	maF-like protein
AZO_RS08195	COG1399	metal-binding, possibly nucleic acid-binding protein
AZO_RS08200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZO_RS08205	COG0416	fatty acid biosynthetic process
AZO_RS08210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZO_RS08215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZO_RS08225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZO_RS08230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZO_RS08240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZO_RS08265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZO_RS08275	COG0583	DNA-binding transcription factor activity
AZO_RS08290	COG0481	GTPase activity
AZO_RS08295	COG0681	Belongs to the peptidase S26 family
AZO_RS08305	COG0571	ribonuclease III activity
AZO_RS08310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZO_RS08315	COG1381	Involved in DNA repair and RecF pathway recombination
AZO_RS08320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZO_RS08325	COG0736	holo-[acyl-carrier-protein] synthase activity
AZO_RS08330	COG1472	Belongs to the glycosyl hydrolase 3 family
AZO_RS08335	COG0322	excinuclease ABC activity
AZO_RS08340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZO_RS08385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZO_RS08395	COG0850	regulation of cytokinetic process
AZO_RS08400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZO_RS08405	COG1393	Belongs to the ArsC family
AZO_RS08410	COG2183	response to ionizing radiation
AZO_RS08425	COG3852	Histidine kinase
AZO_RS08435	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AZO_RS08450	COG4181	ATPase activity
AZO_RS08455	COG0560	Phosphoserine phosphatase
AZO_RS08460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZO_RS08475	COG0598	Magnesium transport protein CorA
AZO_RS08480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZO_RS08510	COG2078	PFAM AMMECR1 domain protein
AZO_RS08515	COG1355	regulation of microtubule-based process
AZO_RS08520	COG3174	membrane
AZO_RS08525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZO_RS08530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZO_RS08540	COG3228	Belongs to the MtfA family
AZO_RS08555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZO_RS08560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZO_RS08565	COG0248	Ppx GppA phosphatase
AZO_RS08570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZO_RS08575	COG1127	ABC transporter
AZO_RS08580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZO_RS08580	COG3218	ABC-type transport auxiliary lipoprotein component
AZO_RS08590	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS08600	COG0084	hydrolase, TatD family'
AZO_RS08605	COG1309	transcriptional regulator
AZO_RS08625	COG1960	acyl-CoA dehydrogenase activity
AZO_RS08630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZO_RS08640	COG2350	Protein conserved in bacteria
AZO_RS08645	COG2917	probably involved in intracellular septation
AZO_RS08675	COG0456	acetyltransferase
AZO_RS08680	COG1573	uracil-dna glycosylase
AZO_RS08685	COG0477	Major facilitator Superfamily
AZO_RS08690	COG0583	DNA-binding transcription factor activity
AZO_RS08730	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AZO_RS08740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZO_RS08745	COG0366	Alpha amylase catalytic
AZO_RS08750	COG0366	Alpha amylase catalytic
AZO_RS08755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZO_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS08815	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZO_RS08840	COG0189	ligase activity
AZO_RS08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZO_RS08895	COG2010	Cytochrome c
AZO_RS08895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZO_RS08900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZO_RS08925	COG0628	permease
AZO_RS08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZO_RS08945	COG1252	NADH dehydrogenase
AZO_RS08970	COG1271	oxidase subunit
AZO_RS08975	COG1294	oxidase, subunit
AZO_RS09005	COG3023	N-Acetylmuramoyl-L-alanine amidase
AZO_RS09025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZO_RS09040	COG0671	phosphoesterase, PA-phosphatase related
AZO_RS09050	COG0438	transferase activity, transferring glycosyl groups
AZO_RS09060	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZO_RS09090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZO_RS09095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZO_RS09100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZO_RS09105	COG1640	4-alpha-glucanotransferase
AZO_RS09115	COG0297	glycogen (starch) synthase activity
AZO_RS09120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZO_RS09135	COG2192	nodulation
AZO_RS09140	COG0859	PFAM glycosyl transferase family 9
AZO_RS09145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZO_RS09155	COG0297	glycogen (starch) synthase activity
AZO_RS09165	COG2323	membrane
AZO_RS09170	COG2204	response regulator
AZO_RS09195	COG2205	protein histidine kinase activity
AZO_RS09200	COG1295	ribonuclease BN
AZO_RS09215	COG5265	(ABC) transporter
AZO_RS09225	COG1285	pathogenesis
AZO_RS09230	COG1058	Belongs to the CinA family
AZO_RS09230	COG1546	Belongs to the CinA family
AZO_RS09240	COG1090	epimerase
AZO_RS09265	COG4771	TonB-dependent receptor
AZO_RS09285	COG1252	NADH dehydrogenase
AZO_RS09320	COG0840	transmembrane signaling receptor activity
AZO_RS09390	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AZO_RS09395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZO_RS09420	COG0564	pseudouridine synthase activity
AZO_RS09430	COG0582	viral genome integration into host DNA
AZO_RS09460	COG0740	serine-type endopeptidase activity
AZO_RS09480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AZO_RS09485	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZO_RS09500	COG3447	MASE1 domain protein
AZO_RS09500	COG5001	Diguanylate cyclase
AZO_RS09500	COG5002	protein histidine kinase activity
AZO_RS09515	COG4181	ATPase activity
AZO_RS09530	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AZO_RS09535	COG2866	Carboxypeptidase
AZO_RS09540	COG3022	response to hydroperoxide
AZO_RS09550	COG0156	8-amino-7-oxononanoate synthase activity
AZO_RS09555	COG2267	carboxylic ester hydrolase activity
AZO_RS09560	COG2226	methyltransferase
AZO_RS09565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZO_RS09570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZO_RS09580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZO_RS09585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZO_RS09590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZO_RS09595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZO_RS09600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZO_RS09620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZO_RS09625	COG0575	Belongs to the CDS family
AZO_RS09630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZO_RS09635	COG0233	cytoplasmic translational termination
AZO_RS09640	COG0528	UMP kinase activity
AZO_RS09645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZO_RS09650	COG0052	Belongs to the universal ribosomal protein uS2 family
AZO_RS09660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZO_RS09670	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZO_RS09675	COG2204	response regulator
AZO_RS09680	COG4191	Histidine kinase
AZO_RS09695	COG2358	TRAP transporter, solute receptor (TAXI family
AZO_RS09700	COG0579	oxidoreductase
AZO_RS09720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZO_RS09725	COG1960	acyl-CoA dehydrogenase activity
AZO_RS09730	COG0583	DNA-binding transcription factor activity
AZO_RS09740	COG1024	Enoyl-CoA hydratase
AZO_RS09755	COG1960	acyl-CoA dehydrogenase activity
AZO_RS09760	COG1960	acyl-CoA dehydrogenase activity
AZO_RS09765	COG1024	Enoyl-CoA hydratase
AZO_RS09780	COG1846	Transcriptional regulator
AZO_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS09800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS09805	COG2354	Protein conserved in bacteria
AZO_RS09820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS09825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZO_RS09835	COG0243	molybdopterin cofactor binding
AZO_RS09840	COG0437	4 iron, 4 sulfur cluster binding
AZO_RS09905	COG0633	Ferredoxin
AZO_RS09905	COG0543	2 iron, 2 sulfur cluster binding
AZO_RS09915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS09925	COG2207	Transcriptional regulator
AZO_RS09935	COG0346	lactoylglutathione lyase activity
AZO_RS09950	COG1802	Transcriptional regulator
AZO_RS09960	COG1063	alcohol dehydrogenase
AZO_RS09965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZO_RS09970	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AZO_RS09975	COG3971	2-oxopent-4-enoate hydratase activity
AZO_RS09980	COG3384	dioxygenase
AZO_RS09985	COG0596	Alpha beta hydrolase
AZO_RS09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZO_RS09995	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZO_RS10020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZO_RS10025	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS10040	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZO_RS10070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZO_RS10100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZO_RS10105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZO_RS10115	COG1196	nuclear chromosome segregation
AZO_RS10120	COG0436	Aminotransferase
AZO_RS10125	COG2171	N-acyltransferase activity
AZO_RS10135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZO_RS10145	COG0784	Response regulator, receiver
AZO_RS10155	COG0633	Ferredoxin
AZO_RS10160	COG0443	Heat shock 70 kDa protein
AZO_RS10165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AZO_RS10175	COG0822	iron-sulfur transferase activity
AZO_RS10180	COG1104	cysteine desulfurase activity
AZO_RS10185	COG1104	cysteine desulfurase activity
AZO_RS10195	COG1045	serine acetyltransferase
AZO_RS10205	COG0483	inositol monophosphate 1-phosphatase activity
AZO_RS10215	COG2161	toxin-antitoxin pair type II binding
AZO_RS10220	COG4115	mRNA cleavage
AZO_RS10250	COG4372	Transposase
AZO_RS10325	COG2003	Belongs to the UPF0758 family
AZO_RS10340	COG5433	transposase activity
AZO_RS10350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZO_RS10365	COG0328	RNA-DNA hybrid ribonuclease activity
AZO_RS10370	COG2226	methyltransferase
AZO_RS10375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZO_RS10385	COG4251	negative regulation of phosphorylation
AZO_RS10385	COG2203	Gaf domain
AZO_RS10385	COG3706	GGDEF domain
AZO_RS10385	COG5001	Diguanylate cyclase
AZO_RS10390	COG1388	LysM domain
AZO_RS10390	COG0741	lytic transglycosylase activity
AZO_RS10400	COG1047	Peptidyl-prolyl cis-trans
AZO_RS10405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZO_RS10410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZO_RS10420	COG0534	Mate efflux family protein
AZO_RS10425	COG1393	Belongs to the ArsC family
AZO_RS10450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZO_RS10455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZO_RS10460	COG0740	serine-type endopeptidase activity
AZO_RS10465	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZO_RS10470	COG2766	serine protein kinase
AZO_RS10475	COG2718	Belongs to the UPF0229 family
AZO_RS10480	COG2719	SpoVR family
AZO_RS10485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZO_RS10485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZO_RS10515	COG0436	Aminotransferase
AZO_RS10550	COG4968	Prepilin-type N-terminal cleavage methylation domain
AZO_RS10555	COG4796	Type ii and iii secretion system protein
AZO_RS10585	COG1459	type II secretion system
AZO_RS10590	COG2165	general secretion pathway protein
AZO_RS10595	COG0741	lytic transglycosylase activity
AZO_RS10595	COG1196	nuclear chromosome segregation
AZO_RS10595	COG0739	heme binding
AZO_RS10605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZO_RS10630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZO_RS10635	COG1185	polyribonucleotide nucleotidyltransferase activity
AZO_RS10640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZO_RS10645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZO_RS10650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZO_RS10655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZO_RS10660	COG0195	Participates in both transcription termination and antitermination
AZO_RS10660	COG2251	uridine kinase activity
AZO_RS10665	COG0779	Required for maturation of 30S ribosomal subunits
AZO_RS10670	COG1187	pseudouridine synthase activity
AZO_RS10675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZO_RS10680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZO_RS10685	COG1994	Peptidase M50
AZO_RS10690	COG0009	L-threonylcarbamoyladenylate synthase
AZO_RS10695	COG0613	PHP domain protein
AZO_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS10720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZO_RS10725	COG1278	Cold shock
AZO_RS10760	COG3706	GGDEF domain
AZO_RS10770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZO_RS10780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZO_RS10785	COG0302	gtp cyclohydrolase
AZO_RS10795	COG0306	phosphate transporter
AZO_RS10805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZO_RS10825	COG0791	NLP P60 protein
AZO_RS10835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AZO_RS10840	COG0148	phosphopyruvate hydratase activity
AZO_RS10845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZO_RS10850	COG0504	CTP synthase activity
AZO_RS10865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZO_RS10870	COG0824	Thioesterase
AZO_RS10910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZO_RS10910	COG0047	phosphoribosylformylglycinamidine synthase activity
AZO_RS10915	COG0671	phosphoesterase, PA-phosphatase related
AZO_RS10925	COG0463	Glycosyl transferase, family 2
AZO_RS10950	COG0739	heme binding
AZO_RS10960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZO_RS10970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZO_RS10975	COG0840	transmembrane signaling receptor activity
AZO_RS10980	COG0183	Belongs to the thiolase family
AZO_RS10985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AZO_RS10990	COG0494	nUDIX hydrolase
AZO_RS11035	COG1666	GTP binding
AZO_RS11040	COG3123	guanosine phosphorylase activity
AZO_RS11050	COG0137	argininosuccinate synthase activity
AZO_RS11055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZO_RS11060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZO_RS11070	COG0268	Binds directly to 16S ribosomal RNA
AZO_RS11090	COG2081	HI0933 family
AZO_RS11100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZO_RS11105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AZO_RS11110	COG0840	transmembrane signaling receptor activity
AZO_RS11130	COG0791	NLP P60 protein
AZO_RS11140	COG1840	ABC-type Fe3 transport system, periplasmic component
AZO_RS11145	COG1178	ABC-type Fe3 transport system permease component
AZO_RS11150	COG3842	ATPase activity
AZO_RS11155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZO_RS11160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AZO_RS11165	COG0167	dihydroorotate dehydrogenase activity
AZO_RS11185	COG3845	ABC transporter
AZO_RS11190	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZO_RS11195	COG1079	Belongs to the binding-protein-dependent transport system permease family
AZO_RS11200	COG4772	TonB-dependent receptor
AZO_RS11210	COG0310	cobalt ion transport
AZO_RS11215	COG0310	cobalt ion transport
AZO_RS11225	COG1122	ATPase activity
AZO_RS11230	COG0402	S-adenosylhomocysteine deaminase activity
AZO_RS11235	COG1671	Belongs to the UPF0178 family
AZO_RS11270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZO_RS11290	COG0438	transferase activity, transferring glycosyl groups
AZO_RS11295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZO_RS11300	COG0438	transferase activity, transferring glycosyl groups
AZO_RS11315	COG0489	protein tyrosine kinase activity
AZO_RS11345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZO_RS11355	COG1573	uracil-dna glycosylase
AZO_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS11375	COG2409	Drug exporters of the RND superfamily
AZO_RS11400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZO_RS11405	COG2259	Doxx family
AZO_RS11435	COG0765	amino acid transport
AZO_RS11440	COG1126	abc transporter atp-binding protein
AZO_RS11470	COG3158	transport of potassium into the cell
AZO_RS11475	COG0657	acetylesterase activity
AZO_RS11480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZO_RS11485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZO_RS11490	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AZO_RS11505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZO_RS11525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZO_RS11530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZO_RS11550	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZO_RS11565	COG0121	glutamine amidotransferase
AZO_RS11575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZO_RS11575	COG2169	Transcriptional regulator
AZO_RS11595	COG2154	pterin-4-alpha-carbinolamine dehydratase
AZO_RS11610	COG1960	acyl-CoA dehydrogenase activity
AZO_RS11620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZO_RS11645	COG1196	nuclear chromosome segregation
AZO_RS11660	COG0366	Alpha amylase catalytic
AZO_RS11675	COG0837	glucose binding
AZO_RS11690	COG1132	(ABC) transporter
AZO_RS11720	COG0297	glycogen (starch) synthase activity
AZO_RS11725	COG0438	transferase activity, transferring glycosyl groups
AZO_RS11730	COG0726	polysaccharide deacetylase
AZO_RS11745	COG0583	DNA-binding transcription factor activity
AZO_RS11750	COG3829	transcription factor binding
AZO_RS11780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZO_RS11790	COG1538	Outer membrane efflux protein
AZO_RS11800	COG0793	Belongs to the peptidase S41A family
AZO_RS11825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZO_RS11845	COG4771	TonB-dependent receptor
AZO_RS11875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZO_RS11880	COG0798	PFAM Bile acid sodium symporter
AZO_RS11895	COG0154	amidase activity
AZO_RS11905	COG1942	4-Oxalocrotonate Tautomerase
AZO_RS11910	COG0583	DNA-binding transcription factor activity
AZO_RS11925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZO_RS11935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZO_RS11940	COG0459	protein refolding
AZO_RS11975	COG1595	DNA-templated transcription, initiation
AZO_RS11980	COG3712	iron ion homeostasis
AZO_RS11985	COG1629	transport
AZO_RS11985	COG4774	siderophore transport
AZO_RS12005	COG3001	Fructosamine kinase
AZO_RS12010	COG0463	Glycosyl transferase, family 2
AZO_RS12065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZO_RS12070	COG1116	anion transmembrane transporter activity
AZO_RS12075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZO_RS12105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZO_RS12120	COG0784	Response regulator, receiver
AZO_RS12120	COG2205	protein histidine kinase activity
AZO_RS12120	COG5002	protein histidine kinase activity
AZO_RS12125	COG3706	GGDEF domain
AZO_RS12125	COG4251	negative regulation of phosphorylation
AZO_RS12125	COG5001	Diguanylate cyclase
AZO_RS12125	COG2203	Gaf domain
AZO_RS12135	COG1764	response to oxidative stress
AZO_RS12145	COG1522	sequence-specific DNA binding
AZO_RS12155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZO_RS12160	COG2176	DNA-directed DNA polymerase activity
AZO_RS12160	COG5002	protein histidine kinase activity
AZO_RS12165	COG0745	RESPONSE REGULATOR receiver
AZO_RS12170	COG5002	protein histidine kinase activity
AZO_RS12180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZO_RS12200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZO_RS12220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZO_RS12230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZO_RS12235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZO_RS12235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZO_RS12240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZO_RS12265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZO_RS12270	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AZO_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS12295	COG1802	Transcriptional regulator
AZO_RS12345	COG3292	Two component regulator propeller
AZO_RS12345	COG0745	RESPONSE REGULATOR receiver
AZO_RS12345	COG2205	protein histidine kinase activity
AZO_RS12360	COG2205	protein histidine kinase activity
AZO_RS12360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZO_RS12450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZO_RS12480	COG0028	Belongs to the TPP enzyme family
AZO_RS12485	COG0583	DNA-binding transcription factor activity
AZO_RS12525	COG3437	response regulator, receiver
AZO_RS12550	COG0490	domain, Protein
AZO_RS12550	COG0471	metal ion transport
AZO_RS12555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZO_RS12575	COG1960	acyl-CoA dehydrogenase activity
AZO_RS12590	COG0183	Belongs to the thiolase family
AZO_RS12595	COG1024	Enoyl-CoA hydratase
AZO_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS12625	COG1309	transcriptional regulator
AZO_RS12630	COG1309	transcriptional regulator
AZO_RS12725	COG0583	DNA-binding transcription factor activity
AZO_RS12740	COG2124	cytochrome p450
AZO_RS12745	COG0633	Ferredoxin
AZO_RS12760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZO_RS12780	COG0667	Aldo Keto reductase
AZO_RS12815	COG2159	amidohydrolase
AZO_RS12820	COG2814	Major facilitator Superfamily
AZO_RS12830	COG2814	Major facilitator Superfamily
AZO_RS12840	COG0840	transmembrane signaling receptor activity
AZO_RS12850	COG0617	tRNA 3'-terminal CCA addition
AZO_RS12920	COG1858	cytochrome C peroxidase
AZO_RS12945	COG0583	DNA-binding transcription factor activity
AZO_RS12950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZO_RS12990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZO_RS12995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZO_RS13000	COG0735	belongs to the Fur family
AZO_RS13005	COG0497	DNA recombination
AZO_RS13010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZO_RS13015	COG1420	regulation of RNA biosynthetic process
AZO_RS13020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZO_RS13025	COG1950	PFAM Membrane protein of
AZO_RS13035	COG0515	serine threonine protein kinase
AZO_RS13035	COG2815	serine threonine protein kinase
AZO_RS13040	COG0402	S-adenosylhomocysteine deaminase activity
AZO_RS13050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZO_RS13080	COG1858	cytochrome C peroxidase
AZO_RS13085	COG1858	cytochrome C peroxidase
AZO_RS13110	COG0583	DNA-binding transcription factor activity
AZO_RS13120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZO_RS13125	COG1278	Cold shock
AZO_RS13145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZO_RS13150	COG0235	Class ii aldolase
AZO_RS13170	COG5002	protein histidine kinase activity
AZO_RS13170	COG3447	MASE1 domain protein
AZO_RS13170	COG5001	Diguanylate cyclase
AZO_RS13195	COG0546	phosphoglycolate phosphatase activity
AZO_RS13200	COG0789	Transcriptional regulator
AZO_RS13240	COG1429	ligase activity, forming nitrogen-metal bonds
AZO_RS13255	COG4106	trans-aconitate 2-methyltransferase activity
AZO_RS13270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZO_RS13275	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AZO_RS13280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZO_RS13320	COG0412	Dienelactone hydrolase
AZO_RS13350	COG0306	phosphate transporter
AZO_RS13365	COG1742	UPF0060 membrane protein
AZO_RS13385	COG1881	PFAM PEBP family protein
AZO_RS13400	COG0450	alkyl hydroperoxide reductase
AZO_RS13425	COG1902	pentaerythritol trinitrate reductase activity
AZO_RS13430	COG3258	Cytochrome c
AZO_RS13440	COG4566	intracellular signal transduction
AZO_RS13445	COG4191	Histidine kinase
AZO_RS13455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZO_RS13470	COG1621	beta-fructofuranosidase activity
AZO_RS13510	COG3045	CreA protein
AZO_RS13560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AZO_RS13575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AZO_RS13600	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AZO_RS13620	COG2257	FlhB HrpN YscU SpaS Family
AZO_RS13625	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AZO_RS13635	COG1677	Flagellar hook-basal body complex protein FliE
AZO_RS13665	COG1157	protein secretion by the type III secretion system
AZO_RS13685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZO_RS13690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZO_RS13700	COG1338	Plays a role in the flagellum-specific transport system
AZO_RS13730	COG1705	Flagellar rod assembly protein muramidase FlgJ
AZO_RS13730	COG3951	Flagellar rod assembly protein muramidase FlgJ
AZO_RS13735	COG1706	bacterial-type flagellum-dependent cell motility
AZO_RS13740	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZO_RS13750	COG4787	bacterial-type flagellum-dependent cell motility
AZO_RS13765	COG1558	bacterial-type flagellum-dependent cell motility
AZO_RS13770	COG1815	bacterial-type flagellum-dependent cell motility
AZO_RS13825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AZO_RS13830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZO_RS13850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZO_RS13855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZO_RS13860	COG0739	heme binding
AZO_RS13865	COG0316	Belongs to the HesB IscA family
AZO_RS13870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZO_RS13875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZO_RS13885	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AZO_RS13895	COG0494	nUDIX hydrolase
AZO_RS13900	COG0442	prolyl-tRNA aminoacylation
AZO_RS13905	COG0741	lytic transglycosylase activity
AZO_RS13915	COG2205	protein histidine kinase activity
AZO_RS13925	COG2204	response regulator
AZO_RS13935	COG0482	sulfurtransferase activity
AZO_RS13975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZO_RS13980	COG2096	Adenosyltransferase
AZO_RS14005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZO_RS14015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZO_RS14025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZO_RS14030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZO_RS14035	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZO_RS14040	COG3028	Belongs to the UPF0307 family
AZO_RS14045	COG0312	modulator of DNA gyrase
AZO_RS14050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZO_RS14055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZO_RS14070	COG2205	protein histidine kinase activity
AZO_RS14075	COG0745	RESPONSE REGULATOR receiver
AZO_RS14080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZO_RS14085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZO_RS14090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZO_RS14090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZO_RS14095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZO_RS14105	COG0793	Belongs to the peptidase S41A family
AZO_RS14115	COG0588	phosphoglycerate mutase activity
AZO_RS14125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZO_RS14135	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZO_RS14145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZO_RS14150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZO_RS14155	COG1040	competence protein
AZO_RS14160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZO_RS14165	COG2226	methyltransferase
AZO_RS14185	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZO_RS14195	COG2833	Protein of unknown function (DUF455)
AZO_RS14200	COG0303	'Molybdopterin
AZO_RS14205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZO_RS14210	COG0704	Plays a role in the regulation of phosphate uptake
AZO_RS14215	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AZO_RS14225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AZO_RS14225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZO_RS14235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZO_RS14240	COG0483	inositol monophosphate 1-phosphatase activity
AZO_RS14255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZO_RS14260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZO_RS14270	COG0126	phosphoglycerate kinase activity
AZO_RS14285	COG0469	pyruvate kinase activity
AZO_RS14305	COG3284	Transcriptional regulator
AZO_RS14325	COG0477	Major facilitator Superfamily
AZO_RS14345	COG3220	belongs to the UPF0276 family
AZO_RS14355	COG2259	Doxx family
AZO_RS14360	COG1595	DNA-templated transcription, initiation
AZO_RS14375	COG2304	oxidoreductase activity
AZO_RS14385	COG0714	Associated with various cellular activities
AZO_RS14390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZO_RS14395	COG2304	oxidoreductase activity
AZO_RS14410	COG0583	DNA-binding transcription factor activity
AZO_RS14415	COG3384	dioxygenase
AZO_RS14420	COG3038	cytochrome b561
AZO_RS14430	COG2353	YceI-like domain
AZO_RS14440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZO_RS14460	COG0339	signal peptide processing
AZO_RS14465	COG1393	Belongs to the ArsC family
AZO_RS14470	COG0004	ammonium transporteR
AZO_RS14485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZO_RS14495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZO_RS14500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZO_RS14505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZO_RS14510	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZO_RS14525	COG0006	proline dipeptidase activity
AZO_RS14530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZO_RS14540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AZO_RS14545	COG0138	bifunctional purine biosynthesis protein purh
AZO_RS14550	COG0151	Belongs to the GarS family
AZO_RS14555	COG0408	coproporphyrinogen oxidase activity
AZO_RS14565	COG0228	four-way junction DNA binding
AZO_RS14570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZO_RS14575	COG0336	Belongs to the RNA methyltransferase TrmD family
AZO_RS14580	COG0335	large ribosomal subunit rRNA binding
AZO_RS14590	COG0795	lipopolysaccharide-transporting ATPase activity
AZO_RS14595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZO_RS14610	COG0525	valine-tRNA ligase activity
AZO_RS14620	COG0842	Transport permease protein
AZO_RS14625	COG0842	Transport permease protein
AZO_RS14625	COG1129	ABC transporter
AZO_RS14630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZO_RS14670	COG0425	Belongs to the sulfur carrier protein TusA family
AZO_RS14680	COG0315	cyclic pyranopterin monophosphate synthase activity
AZO_RS14690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZO_RS14720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZO_RS14725	COG2414	aldehyde ferredoxin oxidoreductase
AZO_RS14735	COG3284	Transcriptional regulator
AZO_RS14755	COG3038	cytochrome b561
AZO_RS14760	COG4654	Cytochrome c, class I
AZO_RS14770	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS14775	COG3284	Transcriptional regulator
AZO_RS14800	COG5002	protein histidine kinase activity
AZO_RS14825	COG2132	Multicopper oxidase
AZO_RS14845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZO_RS14850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZO_RS14885	COG1595	DNA-templated transcription, initiation
AZO_RS14900	COG1741	Belongs to the pirin family
AZO_RS14905	COG2259	Doxx family
AZO_RS14910	COG0583	DNA-binding transcription factor activity
AZO_RS14915	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZO_RS14925	COG2197	response regulator
AZO_RS14970	COG3851	Histidine kinase
AZO_RS14975	COG2197	response regulator
AZO_RS14980	COG0840	transmembrane signaling receptor activity
AZO_RS14990	COG5433	transposase activity
AZO_RS15005	COG4106	trans-aconitate 2-methyltransferase activity
AZO_RS15020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AZO_RS15025	COG1335	isochorismatase
AZO_RS15035	COG0583	DNA-binding transcription factor activity
AZO_RS15060	COG4774	siderophore transport
AZO_RS15070	COG3108	Peptidase M15
AZO_RS15075	COG2989	Protein conserved in bacteria
AZO_RS15090	COG0583	DNA-binding transcription factor activity
AZO_RS15130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZO_RS15140	COG0069	glutamate synthase activity
AZO_RS15150	COG0004	ammonium transporteR
AZO_RS15175	COG1012	belongs to the aldehyde dehydrogenase family
AZO_RS15185	COG4772	TonB-dependent receptor
AZO_RS15195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AZO_RS15255	COG3383	formate dehydrogenase (NAD+) activity
AZO_RS15265	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS15270	COG1773	rubredoxin
AZO_RS15275	COG0604	alcohol dehydrogenase
AZO_RS15275	COG3321	synthase
AZO_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS15280	COG1024	Enoyl-CoA hydratase
AZO_RS15345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZO_RS15365	COG0183	Belongs to the thiolase family
AZO_RS15400	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS15420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZO_RS15455	COG1960	acyl-CoA dehydrogenase activity
AZO_RS15490	COG2010	Cytochrome c
AZO_RS15505	COG0569	domain protein
AZO_RS15510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZO_RS15515	COG0745	RESPONSE REGULATOR receiver
AZO_RS15520	COG2205	protein histidine kinase activity
AZO_RS15545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZO_RS15555	COG1959	2 iron, 2 sulfur cluster binding
AZO_RS15560	COG2239	Acts as a magnesium transporter
AZO_RS15565	COG3245	cytochrome
AZO_RS15615	COG4263	nitrous-oxide reductase activity
AZO_RS15630	COG0527	aspartate kinase activity
AZO_RS15645	COG0720	synthase
AZO_RS15655	COG1511	domain protein
AZO_RS15655	COG3264	Mechanosensitive ion channel
AZO_RS15660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZO_RS15665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZO_RS15665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZO_RS15675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZO_RS15685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZO_RS15695	COG0864	Transcriptional regulator
AZO_RS15705	COG1793	dna ligase
AZO_RS15710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZO_RS15725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZO_RS15735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZO_RS15740	COG0628	permease
AZO_RS15745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZO_RS15755	COG0617	tRNA 3'-terminal CCA addition
AZO_RS15770	COG1428	Deoxynucleoside kinase
AZO_RS15775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZO_RS15780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZO_RS15785	COG0516	GMP reductase activity
AZO_RS15785	COG0517	IMP dehydrogenase activity
AZO_RS15790	COG0308	aminopeptidase N
AZO_RS15825	COG0028	Belongs to the TPP enzyme family
AZO_RS15830	COG0440	acetolactate synthase activity
AZO_RS15835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZO_RS15840	COG1183	phosphatidylcholine synthase activity
AZO_RS15850	COG0784	Response regulator, receiver
AZO_RS15850	COG2198	Histidine kinase
AZO_RS15850	COG2205	protein histidine kinase activity
AZO_RS15860	COG3642	lipopolysaccharide core region biosynthetic process
AZO_RS15865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZO_RS15880	COG1295	ribonuclease BN
AZO_RS15890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZO_RS15895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZO_RS15900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZO_RS15905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZO_RS15920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZO_RS15920	COG3320	Male sterility
AZO_RS15925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZO_RS15935	COG4591	ABC-type transport system involved in lipoprotein release permease component
AZO_RS15940	COG0577	efflux transmembrane transporter activity
AZO_RS15940	COG1136	(ABC) transporter
AZO_RS15945	COG3916	Acyl-homoserine-lactone synthase
AZO_RS15950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZO_RS15960	COG0604	alcohol dehydrogenase
AZO_RS15970	COG1704	LemA family
AZO_RS15980	COG0488	(ABC) transporter
AZO_RS16000	COG0739	heme binding
AZO_RS16000	COG0741	lytic transglycosylase activity
AZO_RS16000	COG1196	nuclear chromosome segregation
AZO_RS16015	COG2204	response regulator
AZO_RS16025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZO_RS16030	COG2030	dehydratase
AZO_RS16065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZO_RS16080	COG0717	Belongs to the dCTP deaminase family
AZO_RS16085	COG0489	protein tyrosine kinase activity
AZO_RS16090	COG3047	cAMP biosynthetic process
AZO_RS16090	COG2885	chlorophyll binding
AZO_RS16095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZO_RS16095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZO_RS16100	COG0659	secondary active sulfate transmembrane transporter activity
AZO_RS16105	COG1254	Belongs to the acylphosphatase family
AZO_RS16110	COG1368	sulfuric ester hydrolase activity
AZO_RS16135	COG0281	malic enzyme
AZO_RS16135	COG0280	phosphate acetyltransferase
AZO_RS16140	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZO_RS16145	COG0210	DNA helicase
AZO_RS16155	COG0495	leucyl-tRNA aminoacylation
AZO_RS16165	COG1466	dna polymerase III delta subunit
AZO_RS16170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZO_RS16175	COG4974	Belongs to the 'phage' integrase family
AZO_RS16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZO_RS16195	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZO_RS16200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZO_RS16205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZO_RS16240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZO_RS16275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZO_RS16280	COG2204	response regulator
AZO_RS16295	COG0071	Belongs to the small heat shock protein (HSP20) family
AZO_RS16300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZO_RS16310	COG0318	PFAM AMP-dependent synthetase and ligase
AZO_RS16355	COG2755	lipolytic protein G-D-S-L family
AZO_RS16355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZO_RS16360	COG2244	polysaccharide biosynthetic process
AZO_RS16365	COG5039	Polysaccharide pyruvyl transferase
AZO_RS16375	COG1215	transferase activity, transferring glycosyl groups
AZO_RS16390	COG0438	transferase activity, transferring glycosyl groups
AZO_RS16420	COG0297	glycogen (starch) synthase activity
AZO_RS16435	COG0367	asparagine synthase
AZO_RS16445	COG0367	asparagine synthase
AZO_RS16450	COG0438	transferase activity, transferring glycosyl groups
AZO_RS16475	COG3267	Type II secretory pathway component ExeA
AZO_RS16475	COG3409	Peptidoglycan-binding domain 1 protein
AZO_RS16485	COG0489	protein tyrosine kinase activity
AZO_RS16510	COG1136	(ABC) transporter
AZO_RS16510	COG0577	efflux transmembrane transporter activity
AZO_RS16535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZO_RS16540	COG1999	signal sequence binding
AZO_RS16545	COG0109	protoheme IX farnesyltransferase activity
AZO_RS16550	COG1612	heme a metabolic process
AZO_RS16580	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AZO_RS16585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZO_RS16595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZO_RS16600	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZO_RS16625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZO_RS16655	COG0604	alcohol dehydrogenase
AZO_RS16670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZO_RS16680	COG0134	indole-3-glycerol-phosphate synthase activity
AZO_RS16685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZO_RS16700	COG0546	phosphoglycolate phosphatase activity
AZO_RS16705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZO_RS16710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZO_RS16715	COG1234	tRNA 3'-trailer cleavage
AZO_RS16725	COG0631	protein serine/threonine phosphatase activity
AZO_RS16730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZO_RS16735	COG0045	succinate-CoA ligase (ADP-forming) activity
AZO_RS16750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZO_RS16760	COG0805	protein transport
AZO_RS16765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZO_RS16770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZO_RS16775	COG0140	phosphoribosyl-ATP diphosphatase activity
AZO_RS16780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZO_RS16785	COG0107	imidazoleglycerol-phosphate synthase activity
AZO_RS16790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZO_RS16795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZO_RS16800	COG0131	Imidazoleglycerol-phosphate dehydratase
AZO_RS16805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZO_RS16810	COG0741	lytic transglycosylase activity
AZO_RS16820	COG1131	(ABC) transporter
AZO_RS16855	COG0436	Aminotransferase
AZO_RS16860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZO_RS16875	COG2084	Dehydrogenase
AZO_RS16880	COG2084	Dehydrogenase
AZO_RS16885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZO_RS16905	COG3411	Ferredoxin
AZO_RS16915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZO_RS16925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZO_RS16955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZO_RS16965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZO_RS16980	COG4251	negative regulation of phosphorylation
AZO_RS16990	COG0629	single-stranded DNA binding
AZO_RS16995	COG2814	Major facilitator Superfamily
AZO_RS17010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZO_RS17015	COG0203	ribosomal protein L17
AZO_RS17020	COG0202	RNA polymerase activity
AZO_RS17025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZO_RS17030	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZO_RS17035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZO_RS17040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZO_RS17045	COG0201	protein transport
AZO_RS17050	COG0200	Binds to the 23S rRNA
AZO_RS17055	COG1841	ribosomal large subunit assembly
AZO_RS17060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZO_RS17065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZO_RS17070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZO_RS17075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZO_RS17080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZO_RS17085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZO_RS17090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZO_RS17095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZO_RS17100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZO_RS17105	COG0255	Belongs to the universal ribosomal protein uL29 family
AZO_RS17110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZO_RS17115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZO_RS17120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZO_RS17125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZO_RS17130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZO_RS17135	COG0089	rRNA binding
AZO_RS17140	COG0088	Forms part of the polypeptide exit tunnel
AZO_RS17145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZO_RS17150	COG0051	transcription antitermination factor activity, RNA binding
AZO_RS17155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZO_RS17160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZO_RS17165	COG0049	tRNA binding
AZO_RS17170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZO_RS17175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZO_RS17180	COG0085	RNA polymerase activity
AZO_RS17185	COG0222	ribosome binding
AZO_RS17190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZO_RS17195	COG0081	regulation of translation
AZO_RS17200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZO_RS17210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZO_RS17220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZO_RS17240	COG0277	FAD linked oxidase domain protein
AZO_RS17260	COG2197	response regulator
AZO_RS17270	COG2205	protein histidine kinase activity
AZO_RS17270	COG0784	Response regulator, receiver
AZO_RS17270	COG2198	Histidine kinase
AZO_RS17280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZO_RS17305	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZO_RS17315	COG1022	Amp-dependent synthetase and ligase
AZO_RS17325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZO_RS17330	COG0352	thiamine-phosphate diphosphorylase activity
AZO_RS17360	COG0840	transmembrane signaling receptor activity
AZO_RS17370	COG0415	Belongs to the DNA photolyase family
AZO_RS17375	COG1678	Uncharacterized ACR, COG1678
AZO_RS17380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZO_RS17385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZO_RS17390	COG0540	Belongs to the ATCase OTCase family
AZO_RS17400	COG1872	DUF167
AZO_RS17405	COG0762	integral membrane protein
AZO_RS17455	COG3290	protein histidine kinase activity
AZO_RS17455	COG0840	transmembrane signaling receptor activity
AZO_RS17460	COG0840	transmembrane signaling receptor activity
AZO_RS17485	COG0437	4 iron, 4 sulfur cluster binding
AZO_RS17490	COG0243	molybdopterin cofactor binding
AZO_RS17490	COG3383	formate dehydrogenase (NAD+) activity
AZO_RS17525	COG0746	molybdenum cofactor guanylyltransferase activity
AZO_RS17535	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZO_RS17540	COG3852	Histidine kinase
AZO_RS17550	COG1981	membrane
AZO_RS17565	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZO_RS17570	COG5002	protein histidine kinase activity
AZO_RS17580	COG4654	Cytochrome c, class I
AZO_RS17585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AZO_RS17590	COG0830	nickel cation binding
AZO_RS17595	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZO_RS17600	COG0804	urea catabolic process
AZO_RS17605	COG0832	Belongs to the urease beta subunit family
AZO_RS17615	COG0831	urea catabolic process
AZO_RS17620	COG0829	nickel cation binding
AZO_RS17625	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZO_RS17625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZO_RS17630	COG1368	sulfuric ester hydrolase activity
AZO_RS17640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZO_RS17645	COG1116	anion transmembrane transporter activity
AZO_RS17650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZO_RS17655	COG1733	regulation of RNA biosynthetic process
AZO_RS17665	COG1492	cobalamin metabolic process
AZO_RS17690	COG0513	Belongs to the DEAD box helicase family
AZO_RS17695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZO_RS17700	COG0778	Nitroreductase
AZO_RS17715	COG5002	protein histidine kinase activity
AZO_RS17715	COG5001	Diguanylate cyclase
AZO_RS17740	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZO_RS17780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZO_RS17785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZO_RS17790	COG0625	glutathione transferase activity
AZO_RS17800	COG0427	acetyl-CoA hydrolase
AZO_RS17810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZO_RS17825	COG0688	phosphatidylethanolamine metabolic process
AZO_RS17830	COG1797	cobyrinic acid a,c-diamide synthase activity
AZO_RS17835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZO_RS17835	COG1648	precorrin-2 dehydrogenase activity
AZO_RS17845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZO_RS17850	COG4139	cobalamin transport
AZO_RS17855	COG4206	TonB-dependent receptor
AZO_RS17870	COG0501	Belongs to the peptidase M48B family
AZO_RS17880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZO_RS17885	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZO_RS17895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZO_RS17895	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZO_RS17900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZO_RS17905	COG0859	PFAM glycosyl transferase family 9
AZO_RS17915	COG0438	transferase activity, transferring glycosyl groups
AZO_RS17940	COG1132	(ABC) transporter
AZO_RS17970	COG0438	transferase activity, transferring glycosyl groups
AZO_RS17975	COG2192	nodulation
AZO_RS17980	COG2755	lipolytic protein G-D-S-L family
AZO_RS17980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZO_RS17990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZO_RS18010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZO_RS18075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZO_RS18100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZO_RS18115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZO_RS18120	COG0799	negative regulation of ribosome biogenesis
AZO_RS18125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZO_RS18130	COG0242	peptide deformylase activity
AZO_RS18135	COG0424	maF-like protein
AZO_RS18140	COG1530	ribonuclease E activity
AZO_RS18170	COG0583	DNA-binding transcription factor activity
AZO_RS18180	COG2818	Glycosylase
AZO_RS18190	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AZO_RS18195	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AZO_RS18205	COG0443	Heat shock 70 kDa protein
AZO_RS18210	COG0741	lytic transglycosylase activity
AZO_RS18220	COG0583	DNA-binding transcription factor activity
AZO_RS18225	COG2814	Major facilitator Superfamily
AZO_RS18235	COG1132	(ABC) transporter
AZO_RS18260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZO_RS18285	COG0067	glutamate synthase
AZO_RS18285	COG0069	glutamate synthase activity
AZO_RS18285	COG0070	glutamate synthase
AZO_RS18290	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AZO_RS18295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZO_RS18300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZO_RS18335	COG1965	Belongs to the frataxin family
AZO_RS18360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZO_RS18365	COG0284	orotidine-5'-phosphate decarboxylase activity
AZO_RS18375	COG0243	molybdopterin cofactor binding
AZO_RS18385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZO_RS18390	COG0708	Exodeoxyribonuclease III
AZO_RS18405	COG4575	ribosome binding
AZO_RS18420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZO_RS18440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZO_RS18450	COG0625	glutathione transferase activity
AZO_RS18455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZO_RS18515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZO_RS18545	COG0180	Tryptophanyl-tRNA synthetase
AZO_RS18565	COG3876	Protein conserved in bacteria
AZO_RS18570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZO_RS18580	COG2226	methyltransferase
AZO_RS18585	COG2020	methyltransferase activity
AZO_RS18595	COG1917	Cupin 2, conserved barrel domain protein
AZO_RS18595	COG2169	Transcriptional regulator
AZO_RS18600	COG4106	trans-aconitate 2-methyltransferase activity
AZO_RS18615	COG0456	acetyltransferase
AZO_RS18625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AZO_RS18630	COG2816	NAD+ diphosphatase activity
AZO_RS18740	COG2814	Major facilitator Superfamily
AZO_RS18760	COG0347	Belongs to the P(II) protein family
AZO_RS18765	COG0004	ammonium transporteR
AZO_RS18770	COG3047	cAMP biosynthetic process
AZO_RS18775	COG0788	formyltetrahydrofolate deformylase activity
AZO_RS18790	COG0488	(ABC) transporter
AZO_RS18815	COG1335	isochorismatase
AZO_RS18830	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AZO_RS18830	COG0506	proline dehydrogenase activity
AZO_RS18830	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AZO_RS18840	COG0189	ligase activity
AZO_RS18860	COG2703	oxygen carrier activity
AZO_RS18905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZO_RS18910	COG0753	catalase activity
AZO_RS18915	COG0402	S-adenosylhomocysteine deaminase activity
AZO_RS18920	COG1652	LysM domain
AZO_RS18940	COG2815	serine threonine protein kinase
AZO_RS18940	COG0515	serine threonine protein kinase
AZO_RS18945	COG0826	peptidase U32
AZO_RS18955	COG3706	GGDEF domain
AZO_RS18965	COG0488	(ABC) transporter
AZO_RS18970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZO_RS18970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZO_RS18975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZO_RS18980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZO_RS19000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AZO_RS19005	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AZO_RS19045	COG1773	rubredoxin
AZO_RS19065	COG0375	protein maturation
AZO_RS19075	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZO_RS19085	COG0409	Hydrogenase expression formation protein
AZO_RS19090	COG0309	Hydrogenase expression formation protein (HypE)
AZO_RS19095	COG2204	response regulator
AZO_RS19125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZO_RS19130	COG1194	a g-specific adenine glycosylase
AZO_RS19180	COG1970	mechanosensitive ion channel activity
AZO_RS19185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZO_RS19200	COG3842	ATPase activity
AZO_RS19210	COG1349	DNA-binding transcription factor activity
AZO_RS19220	COG4302	ethanolamine ammonia-lyase activity
AZO_RS19275	COG3585	molybdate ion transport
AZO_RS19275	COG2005	Transcriptional regulator
AZO_RS19280	COG3842	ATPase activity
AZO_RS19295	COG4208	sulfate ABC transporter
AZO_RS19310	COG2982	Protein involved in outer membrane biogenesis
AZO_RS19320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZO_RS19325	COG1074	ATP-dependent DNA helicase activity
AZO_RS19330	COG4206	TonB-dependent receptor
AZO_RS19340	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZO_RS19345	COG1785	Belongs to the alkaline phosphatase family
AZO_RS19355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZO_RS19355	COG1024	Enoyl-CoA hydratase
AZO_RS19360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AZO_RS19365	COG0583	DNA-binding transcription factor activity
AZO_RS19370	COG0473	3-isopropylmalate dehydrogenase activity
AZO_RS19375	COG3530	Putative quorum-sensing-regulated virulence factor
AZO_RS19380	COG2095	MarC family integral membrane protein
AZO_RS19405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZO_RS19410	COG0022	dehydrogenase e1 component
AZO_RS19425	COG0095	Lipoate-protein ligase
AZO_RS19445	COG3284	Transcriptional regulator
AZO_RS19495	COG0631	protein serine/threonine phosphatase activity
AZO_RS19610	COG2815	serine threonine protein kinase
AZO_RS19610	COG0515	serine threonine protein kinase
AZO_RS19615	COG0840	transmembrane signaling receptor activity
AZO_RS19625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZO_RS19640	COG1028	Short-chain dehydrogenase reductase Sdr
AZO_RS19645	COG0475	glutathione-regulated potassium exporter activity
AZO_RS19650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZO_RS19690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZO_RS19695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZO_RS19705	COG4235	cytochrome complex assembly
AZO_RS19710	COG3088	subunit of a heme lyase
AZO_RS19715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZO_RS19725	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZO_RS19740	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZO_RS19745	COG4133	protoheme IX ABC transporter activity
AZO_RS19755	COG3005	denitrification pathway
AZO_RS19760	COG3043	anaerobic respiration
AZO_RS19765	COG0348	domain, Protein
AZO_RS19770	COG0437	4 iron, 4 sulfur cluster binding
AZO_RS19775	COG0243	molybdopterin cofactor binding
AZO_RS19785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZO_RS19785	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZO_RS19795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZO_RS19795	COG2205	protein histidine kinase activity
AZO_RS19800	COG2205	protein histidine kinase activity
AZO_RS19800	COG3437	response regulator, receiver
AZO_RS19800	COG3850	Histidine kinase
AZO_RS19800	COG4999	Histidine kinase
AZO_RS19805	COG5002	protein histidine kinase activity
AZO_RS19805	COG2176	DNA-directed DNA polymerase activity
AZO_RS19810	COG2226	methyltransferase
AZO_RS19820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZO_RS19825	COG1758	RNA polymerase activity
AZO_RS19830	COG0194	GDP metabolic process
AZO_RS19850	COG0587	DNA-directed DNA polymerase activity
AZO_RS19860	COG0789	Transcriptional regulator
AZO_RS19865	COG1561	YicC-like family, N-terminal region
AZO_RS19870	COG3266	domain, Protein
AZO_RS19870	COG0515	serine threonine protein kinase
AZO_RS19875	COG0631	protein serine/threonine phosphatase activity
AZO_RS19880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZO_RS19885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZO_RS19890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZO_RS19900	COG0616	signal peptide processing
AZO_RS19905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZO_RS19910	COG2022	thiamine diphosphate biosynthetic process
AZO_RS19920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZO_RS19925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZO_RS19925	COG2813	Specifically methylates the guanine in position
AZO_RS19940	COG2223	nitrite transmembrane transporter activity
AZO_RS19950	COG0288	reversible hydration of carbon dioxide
AZO_RS19955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZO_RS19960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZO_RS19965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZO_RS19970	COG0569	domain protein
AZO_RS19975	COG2204	response regulator
AZO_RS19980	COG5000	phosphorelay sensor kinase activity
AZO_RS19995	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZO_RS20000	COG0730	response to heat
AZO_RS20005	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZO_RS20010	COG0706	membrane insertase activity
AZO_RS20015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZO_RS20020	COG0594	ribonuclease P activity
AZO_RS20030	COG4977	sequence-specific DNA binding
AZO_RS20030	COG1917	Cupin 2, conserved barrel domain protein
AZO_RS20060	COG3706	GGDEF domain
AZO_RS20105	COG1187	pseudouridine synthase activity
AZO_RS20150	COG5002	protein histidine kinase activity
AZO_RS20180	COG1017	nitric oxide dioxygenase activity
AZO_RS20180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZO_RS20210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AZO_RS20225	COG2205	protein histidine kinase activity
AZO_RS20240	COG2202	Pas domain
AZO_RS20240	COG2205	protein histidine kinase activity
AZO_RS20245	COG2205	protein histidine kinase activity
AZO_RS20260	COG2205	protein histidine kinase activity
AZO_RS20260	COG5002	protein histidine kinase activity
AZO_RS20260	COG0784	Response regulator, receiver
AZO_RS20265	COG4916	TIR domain
AZO_RS20325	COG0297	glycogen (starch) synthase activity
AZO_RS20330	COG4269	membrane
AZO_RS20335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZO_RS20345	COG0840	transmembrane signaling receptor activity
AZO_RS20365	COG5002	protein histidine kinase activity
AZO_RS20365	COG2205	protein histidine kinase activity
AZO_RS20365	COG0784	Response regulator, receiver