locus-tag	class	description
CDA09_RS00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDA09_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDA09_RS00085	COG2203	Gaf domain
CDA09_RS00085	COG3706	GGDEF domain
CDA09_RS00085	COG4251	negative regulation of phosphorylation
CDA09_RS00085	COG5001	Diguanylate cyclase
CDA09_RS00095	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDA09_RS00120	COG1116	anion transmembrane transporter activity
CDA09_RS00125	COG0686	Belongs to the AlaDH PNT family
CDA09_RS00145	COG0583	DNA-binding transcription factor activity
CDA09_RS00150	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS00155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS00165	COG2974	May be involved in recombination
CDA09_RS00175	COG1187	pseudouridine synthase activity
CDA09_RS00185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDA09_RS00195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDA09_RS00225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDA09_RS00230	COG4206	TonB-dependent receptor
CDA09_RS00240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDA09_RS00250	COG2922	Belongs to the Smg family
CDA09_RS00255	COG0758	DNA mediated transformation
CDA09_RS00265	COG0242	peptide deformylase activity
CDA09_RS00270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDA09_RS00275	COG0501	Belongs to the peptidase M48B family
CDA09_RS00280	COG3852	Histidine kinase
CDA09_RS00290	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDA09_RS00310	COG0746	molybdenum cofactor guanylyltransferase activity
CDA09_RS00315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDA09_RS00345	COG3383	formate dehydrogenase (NAD+) activity
CDA09_RS00350	COG0437	4 iron, 4 sulfur cluster binding
CDA09_RS00405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDA09_RS00410	COG0765	amino acid transport
CDA09_RS00415	COG0765	amino acid transport
CDA09_RS00420	COG1126	abc transporter atp-binding protein
CDA09_RS00425	COG2824	Alkylphosphonate utilization operon protein PhnA
CDA09_RS00440	COG0445	tRNA wobble uridine modification
CDA09_RS00445	COG0357	Ribosomal RNA small subunit methyltransferase G
CDA09_RS00450	COG1192	Involved in chromosome partitioning
CDA09_RS00455	COG1475	DNA binding
CDA09_RS00465	COG0356	it plays a direct role in the translocation of protons across the membrane
CDA09_RS00475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDA09_RS00480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDA09_RS00485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDA09_RS00490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDA09_RS00495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDA09_RS00500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDA09_RS00515	COG2226	methyltransferase
CDA09_RS00525	COG0745	RESPONSE REGULATOR receiver
CDA09_RS00545	COG0121	glutamine amidotransferase
CDA09_RS00550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDA09_RS00560	COG0154	amidase activity
CDA09_RS00565	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDA09_RS00570	COG1077	Cell shape determining protein MreB Mrl
CDA09_RS00585	COG0768	penicillin binding
CDA09_RS00590	COG0772	Belongs to the SEDS family
CDA09_RS00600	COG1686	Belongs to the peptidase S11 family
CDA09_RS00610	COG2921	Belongs to the UPF0250 family
CDA09_RS00615	COG0321	lipoyl(octanoyl) transferase activity
CDA09_RS00620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDA09_RS00640	COG0840	transmembrane signaling receptor activity
CDA09_RS00660	COG4566	intracellular signal transduction
CDA09_RS00725	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS00730	COG0514	ATP-dependent DNA helicase (RecQ)
CDA09_RS00770	COG0683	leucine binding
CDA09_RS00790	COG0500	methyltransferase
CDA09_RS00795	COG3001	Fructosamine kinase
CDA09_RS00810	COG2271	Major facilitator Superfamily
CDA09_RS00825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDA09_RS00840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDA09_RS00855	COG3179	chitinase
CDA09_RS00865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDA09_RS00870	COG3842	ATPase activity
CDA09_RS00875	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDA09_RS00880	COG1177	transmembrane transport
CDA09_RS00885	COG1132	(ABC) transporter
CDA09_RS00930	COG2205	protein histidine kinase activity
CDA09_RS00935	COG1131	(ABC) transporter
CDA09_RS00950	COG3134	Outer membrane lipoprotein
CDA09_RS00965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDA09_RS00970	COG1074	ATP-dependent DNA helicase activity
CDA09_RS00975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDA09_RS00980	COG4191	Histidine kinase
CDA09_RS00985	COG2204	response regulator
CDA09_RS00990	COG1459	type II secretion system
CDA09_RS01000	COG0739	heme binding
CDA09_RS01000	COG0741	lytic transglycosylase activity
CDA09_RS01000	COG1196	nuclear chromosome segregation
CDA09_RS01050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDA09_RS01080	COG2165	general secretion pathway protein
CDA09_RS01095	COG1278	Cold shock
CDA09_RS01105	COG0330	HflC and HflK could
CDA09_RS01135	COG0477	Major facilitator Superfamily
CDA09_RS01145	COG1305	Transglutaminase-like
CDA09_RS01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDA09_RS01160	COG3045	CreA protein
CDA09_RS01170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDA09_RS01175	COG0484	heat shock protein binding
CDA09_RS01200	COG0194	GDP metabolic process
CDA09_RS01205	COG1758	RNA polymerase activity
CDA09_RS01210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDA09_RS01215	COG0523	cobalamin synthesis protein
CDA09_RS01220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDA09_RS01245	COG3850	Histidine kinase
CDA09_RS01250	COG2197	response regulator
CDA09_RS01265	COG0243	molybdopterin cofactor binding
CDA09_RS01270	COG0437	4 iron, 4 sulfur cluster binding
CDA09_RS01275	COG0348	domain, Protein
CDA09_RS01280	COG3043	anaerobic respiration
CDA09_RS01285	COG3005	denitrification pathway
CDA09_RS01290	COG4133	protoheme IX ABC transporter activity
CDA09_RS01295	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDA09_RS01305	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDA09_RS01310	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CDA09_RS01320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDA09_RS01325	COG3088	subunit of a heme lyase
CDA09_RS01330	COG3088	subunit of a heme lyase
CDA09_RS01330	COG4235	cytochrome complex assembly
CDA09_RS01345	COG2010	Cytochrome c
CDA09_RS01355	COG2204	response regulator
CDA09_RS01360	COG4191	Histidine kinase
CDA09_RS01375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDA09_RS01385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDA09_RS01470	COG3245	cytochrome
CDA09_RS01475	COG2010	Cytochrome c
CDA09_RS01515	COG1215	transferase activity, transferring glycosyl groups
CDA09_RS01545	COG3706	GGDEF domain
CDA09_RS01555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDA09_RS01575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDA09_RS01580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDA09_RS01635	COG0835	chemotaxis
CDA09_RS01640	COG3290	protein histidine kinase activity
CDA09_RS01640	COG0840	transmembrane signaling receptor activity
CDA09_RS01650	COG2201	protein-glutamate methylesterase activity
CDA09_RS01670	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS01675	COG1024	Enoyl-CoA hydratase
CDA09_RS01680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS01685	COG2050	protein possibly involved in aromatic compounds catabolism
CDA09_RS01695	COG3396	Phenylacetate-CoA oxygenase
CDA09_RS01700	COG3460	Phenylacetate-CoA oxygenase
CDA09_RS01705	COG3396	Phenylacetate-CoA oxygenase
CDA09_RS01710	COG2151	metal-sulfur cluster biosynthetic enzyme
CDA09_RS01715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDA09_RS01735	COG0411	ABC transporter
CDA09_RS01755	COG0583	DNA-binding transcription factor activity
CDA09_RS01765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDA09_RS01775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDA09_RS01790	COG0513	Belongs to the DEAD box helicase family
CDA09_RS01795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDA09_RS01800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDA09_RS01815	COG4232	protein-disulfide reductase activity
CDA09_RS01835	COG0745	RESPONSE REGULATOR receiver
CDA09_RS01840	COG2205	protein histidine kinase activity
CDA09_RS01865	COG3279	Response regulator of the LytR AlgR family
CDA09_RS01880	COG2203	Gaf domain
CDA09_RS01880	COG4251	negative regulation of phosphorylation
CDA09_RS01880	COG5001	Diguanylate cyclase
CDA09_RS01880	COG3706	GGDEF domain
CDA09_RS01895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDA09_RS01930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDA09_RS01935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDA09_RS01945	COG1845	cytochrome c oxidase, subunit III
CDA09_RS01960	COG0861	Integral membrane protein TerC family
CDA09_RS01985	COG1131	(ABC) transporter
CDA09_RS01990	COG0625	glutathione transferase activity
CDA09_RS01995	COG2945	thiolester hydrolase activity
CDA09_RS01995	COG0596	Alpha beta hydrolase
CDA09_RS02010	COG3154	lipid carrier protein
CDA09_RS02015	COG0826	peptidase U32
CDA09_RS02020	COG0826	peptidase U32
CDA09_RS02045	COG1331	Highly conserved protein containing a thioredoxin domain
CDA09_RS02080	COG0581	inorganic phosphate transmembrane transporter activity
CDA09_RS02085	COG0573	inorganic phosphate transmembrane transporter activity
CDA09_RS02090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDA09_RS02100	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDA09_RS02120	COG0346	lactoylglutathione lyase activity
CDA09_RS02145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDA09_RS02150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDA09_RS02155	COG0018	arginyl-trna synthetase
CDA09_RS02170	COG0300	oxidoreductase activity
CDA09_RS02175	COG2902	Dehydrogenase
CDA09_RS02185	COG0826	peptidase U32
CDA09_RS02230	COG3158	transport of potassium into the cell
CDA09_RS02235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDA09_RS02245	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDA09_RS02250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS02255	COG0789	Transcriptional regulator
CDA09_RS02260	COG0288	reversible hydration of carbon dioxide
CDA09_RS02265	COG0183	Belongs to the thiolase family
CDA09_RS02270	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS02275	COG1024	Enoyl-CoA hydratase
CDA09_RS02295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS02300	COG1660	Displays ATPase and GTPase activities
CDA09_RS02320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDA09_RS02335	COG1301	dicarboxylic acid transport
CDA09_RS02345	COG0217	transcriptional regulatory protein
CDA09_RS02355	COG0433	COG0433 Predicted ATPase
CDA09_RS02380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDA09_RS02390	COG1278	Cold shock
CDA09_RS02395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDA09_RS02405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDA09_RS02415	COG1560	Kdo2-lipid A biosynthetic process
CDA09_RS02420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDA09_RS02430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDA09_RS02440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDA09_RS02450	COG2255	four-way junction helicase activity
CDA09_RS02455	COG0632	four-way junction helicase activity
CDA09_RS02465	COG1530	ribonuclease E activity
CDA09_RS02470	COG0424	maF-like protein
CDA09_RS02475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDA09_RS02480	COG0799	negative regulation of ribosome biogenesis
CDA09_RS02485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDA09_RS02500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDA09_RS02520	COG2192	nodulation
CDA09_RS02525	COG0726	polysaccharide deacetylase
CDA09_RS02535	COG0438	transferase activity, transferring glycosyl groups
CDA09_RS02550	COG0438	transferase activity, transferring glycosyl groups
CDA09_RS02555	COG0438	transferase activity, transferring glycosyl groups
CDA09_RS02570	COG0367	asparagine synthase
CDA09_RS02585	COG1132	(ABC) transporter
CDA09_RS02595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDA09_RS02600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDA09_RS02600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDA09_RS02605	COG2890	protein-(glutamine-N5) methyltransferase activity
CDA09_RS02610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDA09_RS02615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDA09_RS02635	COG4139	cobalamin transport
CDA09_RS02640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDA09_RS02650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDA09_RS02650	COG1648	precorrin-2 dehydrogenase activity
CDA09_RS02660	COG2818	Glycosylase
CDA09_RS02665	COG0583	DNA-binding transcription factor activity
CDA09_RS02685	COG1139	Iron-sulfur cluster binding protein
CDA09_RS02690	COG0247	lactate metabolic process
CDA09_RS02695	COG0697	spore germination
CDA09_RS02705	COG0583	DNA-binding transcription factor activity
CDA09_RS02710	COG1032	radical SAM domain protein
CDA09_RS02715	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDA09_RS02720	COG0741	lytic transglycosylase activity
CDA09_RS02725	COG0436	Aminotransferase
CDA09_RS02735	COG0280	phosphate acetyltransferase
CDA09_RS02735	COG0281	malic enzyme
CDA09_RS02745	COG1686	Belongs to the peptidase S11 family
CDA09_RS02755	COG1187	pseudouridine synthase activity
CDA09_RS02770	COG0577	efflux transmembrane transporter activity
CDA09_RS02770	COG1136	(ABC) transporter
CDA09_RS02780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS02785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDA09_RS02790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDA09_RS02810	COG1643	Atp-dependent helicase
CDA09_RS02815	COG0360	Binds together with S18 to 16S ribosomal RNA
CDA09_RS02820	COG2965	DNA replication, synthesis of RNA primer
CDA09_RS02825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDA09_RS02830	COG0359	binds to the 23S rRNA
CDA09_RS02835	COG0305	Participates in initiation and elongation during chromosome replication
CDA09_RS02865	COG0657	acetylesterase activity
CDA09_RS02885	COG0488	(ABC) transporter
CDA09_RS02895	COG1704	LemA family
CDA09_RS02905	COG0604	alcohol dehydrogenase
CDA09_RS02910	COG0745	RESPONSE REGULATOR receiver
CDA09_RS02915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS02925	COG0741	lytic transglycosylase activity
CDA09_RS02930	COG1459	type II secretion system
CDA09_RS02975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDA09_RS02980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDA09_RS02985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDA09_RS02990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDA09_RS03000	COG0277	FAD linked oxidase domain protein
CDA09_RS03005	COG0277	FAD linked oxidase domain protein
CDA09_RS03010	COG0247	lactate metabolic process
CDA09_RS03015	COG0631	protein serine/threonine phosphatase activity
CDA09_RS03020	COG0598	Magnesium transport protein CorA
CDA09_RS03030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDA09_RS03045	COG5001	Diguanylate cyclase
CDA09_RS03045	COG3300	MHYT domain
CDA09_RS03050	COG0513	Belongs to the DEAD box helicase family
CDA09_RS03055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CDA09_RS03070	COG0584	glycerophosphoryl diester phosphodiesterase
CDA09_RS03075	COG0142	geranyltranstransferase activity
CDA09_RS03090	COG2353	YceI-like domain
CDA09_RS03095	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CDA09_RS03115	COG4654	Cytochrome c, class I
CDA09_RS03120	COG0583	DNA-binding transcription factor activity
CDA09_RS03135	COG1473	amidohydrolase
CDA09_RS03140	COG0583	DNA-binding transcription factor activity
CDA09_RS03150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDA09_RS03155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS03170	COG0583	DNA-binding transcription factor activity
CDA09_RS03175	COG0509	glycine decarboxylation via glycine cleavage system
CDA09_RS03185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDA09_RS03190	COG1113	amino acid transport
CDA09_RS03195	COG1760	l-serine dehydratase
CDA09_RS03200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDA09_RS03205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDA09_RS03220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDA09_RS03225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDA09_RS03270	COG0492	ferredoxin-NADP+ reductase activity
CDA09_RS03285	COG2030	dehydratase
CDA09_RS03290	COG1469	GTP cyclohydrolase I activity
CDA09_RS03295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDA09_RS03300	COG0142	geranyltranstransferase activity
CDA09_RS03305	COG1722	exodeoxyribonuclease VII activity
CDA09_RS03315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDA09_RS03320	COG1047	Peptidyl-prolyl cis-trans
CDA09_RS03325	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDA09_RS03330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDA09_RS03335	COG0196	riboflavin kinase activity
CDA09_RS03340	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDA09_RS03345	COG0802	atpase or kinase
CDA09_RS03355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDA09_RS03370	COG0697	spore germination
CDA09_RS03375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDA09_RS03380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDA09_RS03390	COG0583	DNA-binding transcription factor activity
CDA09_RS03395	COG2205	protein histidine kinase activity
CDA09_RS03415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDA09_RS03420	COG0542	response to heat
CDA09_RS03425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDA09_RS03430	COG1278	Cold shock
CDA09_RS03435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDA09_RS03440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDA09_RS03445	COG2003	Belongs to the UPF0758 family
CDA09_RS03450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDA09_RS03455	COG0756	dUTP diphosphatase activity
CDA09_RS03465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDA09_RS03470	COG2863	cytochrome
CDA09_RS03485	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CDA09_RS03495	COG0538	isocitrate dehydrogenase activity
CDA09_RS03515	COG1346	cytolysis
CDA09_RS03525	COG4206	TonB-dependent receptor
CDA09_RS03540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDA09_RS03555	COG0583	DNA-binding transcription factor activity
CDA09_RS03570	COG2308	Evidence 4 Homologs of previously reported genes of
CDA09_RS03690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDA09_RS03695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDA09_RS03700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDA09_RS03720	COG4974	Belongs to the 'phage' integrase family
CDA09_RS03730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDA09_RS03735	COG1466	dna polymerase III delta subunit
CDA09_RS03745	COG0495	leucyl-tRNA aminoacylation
CDA09_RS03755	COG0210	DNA helicase
CDA09_RS03760	COG1192	Involved in chromosome partitioning
CDA09_RS03765	COG0281	malic enzyme
CDA09_RS03765	COG0280	phosphate acetyltransferase
CDA09_RS03790	COG0450	alkyl hydroperoxide reductase
CDA09_RS03795	COG1254	Belongs to the acylphosphatase family
CDA09_RS03800	COG0659	secondary active sulfate transmembrane transporter activity
CDA09_RS03805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDA09_RS03805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDA09_RS03810	COG2885	chlorophyll binding
CDA09_RS03810	COG3047	cAMP biosynthetic process
CDA09_RS03815	COG0489	protein tyrosine kinase activity
CDA09_RS03820	COG0717	Belongs to the dCTP deaminase family
CDA09_RS03835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDA09_RS03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDA09_RS03875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDA09_RS03880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CDA09_RS03890	COG0494	nUDIX hydrolase
CDA09_RS03895	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDA09_RS03900	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CDA09_RS03905	COG0237	dephospho-CoA kinase activity
CDA09_RS03915	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CDA09_RS03920	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDA09_RS03930	COG2204	response regulator
CDA09_RS03935	COG3852	Histidine kinase
CDA09_RS03945	COG0174	glutamine synthetase
CDA09_RS03960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDA09_RS03965	COG3568	Endonuclease Exonuclease Phosphatase
CDA09_RS03970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDA09_RS03985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDA09_RS03995	COG0463	Glycosyl transferase, family 2
CDA09_RS04010	COG0564	pseudouridine synthase activity
CDA09_RS04015	COG0012	GTP binding
CDA09_RS04020	COG0193	aminoacyl-tRNA hydrolase activity
CDA09_RS04025	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDA09_RS04030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDA09_RS04040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDA09_RS04045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDA09_RS04055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDA09_RS04060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDA09_RS04065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDA09_RS04070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDA09_RS04075	COG0742	ribosomal rna small subunit methyltransferase
CDA09_RS04085	COG0612	Peptidase, M16
CDA09_RS04095	COG2884	Cell division ATP-binding protein ftsE
CDA09_RS04100	COG2177	Part of the ABC transporter FtsEX involved in
CDA09_RS04110	COG4191	Histidine kinase
CDA09_RS04110	COG0784	Response regulator, receiver
CDA09_RS04120	COG1607	acyl-coa hydrolase
CDA09_RS04125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDA09_RS04150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDA09_RS04155	COG1702	phosphate starvation-inducible protein PhoH
CDA09_RS04160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDA09_RS04165	COG4535	Mg2 and Co2 transporter CorC
CDA09_RS04170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDA09_RS04175	COG0752	glycyl-tRNA synthetase alpha subunit
CDA09_RS04180	COG0751	glycine-tRNA ligase activity
CDA09_RS04185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDA09_RS04190	COG0204	Acyl-transferase
CDA09_RS04210	COG1024	Enoyl-CoA hydratase
CDA09_RS04235	COG1127	ABC transporter
CDA09_RS04240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDA09_RS04245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDA09_RS04250	COG2853	Lipoprotein
CDA09_RS04265	COG1131	(ABC) transporter
CDA09_RS04270	COG0842	Transport permease protein
CDA09_RS04280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDA09_RS04285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDA09_RS04290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDA09_RS04295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDA09_RS04300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDA09_RS04305	COG0131	Imidazoleglycerol-phosphate dehydratase
CDA09_RS04310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDA09_RS04315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDA09_RS04320	COG0107	imidazoleglycerol-phosphate synthase activity
CDA09_RS04325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDA09_RS04330	COG0140	phosphoribosyl-ATP diphosphatase activity
CDA09_RS04340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDA09_RS04345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDA09_RS04350	COG0805	protein transport
CDA09_RS04355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDA09_RS04360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDA09_RS04375	COG0045	succinate-CoA ligase (ADP-forming) activity
CDA09_RS04380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDA09_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDA09_RS04400	COG0306	phosphate transporter
CDA09_RS04405	COG0105	UTP biosynthetic process
CDA09_RS04410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDA09_RS04420	COG1426	Protein conserved in bacteria
CDA09_RS04425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDA09_RS04430	COG0124	histidyl-tRNA synthetase
CDA09_RS04435	COG2976	Protein conserved in bacteria
CDA09_RS04440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDA09_RS04445	COG1160	GTP binding
CDA09_RS04450	COG1923	regulation of RNA biosynthetic process
CDA09_RS04455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDA09_RS04460	COG0330	HflC and HflK could
CDA09_RS04465	COG0330	HflC and HflK could
CDA09_RS04475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDA09_RS04480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDA09_RS04495	COG0557	exoribonuclease II activity
CDA09_RS04500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDA09_RS04505	COG3707	response regulator
CDA09_RS04520	COG0535	radical SAM domain protein
CDA09_RS04530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CDA09_RS04535	COG0167	dihydroorotate dehydrogenase activity
CDA09_RS04540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDA09_RS04545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDA09_RS04550	COG1116	anion transmembrane transporter activity
CDA09_RS04560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDA09_RS04570	COG2223	nitrite transmembrane transporter activity
CDA09_RS04575	COG0515	serine threonine protein kinase
CDA09_RS04580	COG0243	molybdopterin cofactor binding
CDA09_RS04585	COG5001	Diguanylate cyclase
CDA09_RS04590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS04605	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDA09_RS04610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDA09_RS04615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDA09_RS04620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDA09_RS04625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDA09_RS04630	COG0723	plastoquinol--plastocyanin reductase activity
CDA09_RS04635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDA09_RS04640	COG2857	Cytochrome c1
CDA09_RS04645	COG0625	glutathione transferase activity
CDA09_RS04650	COG2969	positive regulation of protein catabolic process
CDA09_RS04655	COG0438	transferase activity, transferring glycosyl groups
CDA09_RS04660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDA09_RS04665	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDA09_RS04675	COG0506	proline dehydrogenase activity
CDA09_RS04675	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDA09_RS04675	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDA09_RS04705	COG1448	Aminotransferase
CDA09_RS04710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDA09_RS04715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CDA09_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS04750	COG0028	Belongs to the TPP enzyme family
CDA09_RS04760	COG0679	Auxin Efflux Carrier
CDA09_RS04775	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS04805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDA09_RS04810	COG0459	protein refolding
CDA09_RS04820	COG0642	Histidine kinase
CDA09_RS04825	COG3162	membrane
CDA09_RS04925	COG0175	sulfate reduction
CDA09_RS04930	COG0730	response to heat
CDA09_RS04935	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDA09_RS04940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDA09_RS04945	COG2890	protein-(glutamine-N5) methyltransferase activity
CDA09_RS04950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDA09_RS04955	COG0515	serine threonine protein kinase
CDA09_RS04955	COG2815	serine threonine protein kinase
CDA09_RS04960	COG0165	Argininosuccinate lyase
CDA09_RS04970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CDA09_RS04975	COG0181	hydroxymethylbilane synthase activity
CDA09_RS04985	COG2959	enzyme of heme biosynthesis
CDA09_RS04995	COG0408	coproporphyrinogen oxidase activity
CDA09_RS05000	COG0151	Belongs to the GarS family
CDA09_RS05010	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDA09_RS05015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDA09_RS05020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDA09_RS05025	COG0006	proline dipeptidase activity
CDA09_RS05040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CDA09_RS05045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDA09_RS05050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDA09_RS05055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDA09_RS05065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDA09_RS05085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDA09_RS05105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDA09_RS05115	COG2885	chlorophyll binding
CDA09_RS05120	COG5001	Diguanylate cyclase
CDA09_RS05120	COG5002	protein histidine kinase activity
CDA09_RS05140	COG0778	Nitroreductase
CDA09_RS05145	COG0469	pyruvate kinase activity
CDA09_RS05160	COG0126	phosphoglycerate kinase activity
CDA09_RS05165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDA09_RS05170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDA09_RS05175	COG3954	Phosphoribulokinase
CDA09_RS05185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDA09_RS05195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDA09_RS05195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDA09_RS05200	COG5001	Diguanylate cyclase
CDA09_RS05200	COG3300	MHYT domain
CDA09_RS05205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CDA09_RS05210	COG0704	Plays a role in the regulation of phosphate uptake
CDA09_RS05215	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDA09_RS05220	COG0303	'Molybdopterin
CDA09_RS05230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDA09_RS05245	COG2226	methyltransferase
CDA09_RS05250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDA09_RS05255	COG1040	competence protein
CDA09_RS05260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDA09_RS05265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDA09_RS05275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CDA09_RS05285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDA09_RS05290	COG0640	Transcriptional regulator
CDA09_RS05295	COG0588	phosphoglycerate mutase activity
CDA09_RS05305	COG0793	Belongs to the peptidase S41A family
CDA09_RS05315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDA09_RS05315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDA09_RS05320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDA09_RS05325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDA09_RS05330	COG0406	alpha-ribazole phosphatase activity
CDA09_RS05335	COG0312	modulator of DNA gyrase
CDA09_RS05340	COG3028	Belongs to the UPF0307 family
CDA09_RS05345	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDA09_RS05350	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CDA09_RS05355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDA09_RS05370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDA09_RS05375	COG2096	Adenosyltransferase
CDA09_RS05380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDA09_RS05425	COG0482	sulfurtransferase activity
CDA09_RS05445	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDA09_RS05455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDA09_RS05460	COG0312	modulator of DNA gyrase
CDA09_RS05470	COG2204	response regulator
CDA09_RS05480	COG2205	protein histidine kinase activity
CDA09_RS05495	COG0741	lytic transglycosylase activity
CDA09_RS05500	COG0442	prolyl-tRNA aminoacylation
CDA09_RS05505	COG0494	nUDIX hydrolase
CDA09_RS05515	COG1592	Rubrerythrin
CDA09_RS05520	COG0247	lactate metabolic process
CDA09_RS05535	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CDA09_RS05540	COG1765	OsmC-like protein
CDA09_RS05545	COG3033	Beta-eliminating lyase
CDA09_RS05550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDA09_RS05555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDA09_RS05560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDA09_RS05565	COG0316	Belongs to the HesB IscA family
CDA09_RS05575	COG0739	heme binding
CDA09_RS05580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDA09_RS05630	COG2423	ornithine cyclodeaminase activity
CDA09_RS05635	COG0583	DNA-binding transcription factor activity
CDA09_RS05655	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS05660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDA09_RS05670	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS05680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS05685	COG0402	S-adenosylhomocysteine deaminase activity
CDA09_RS05710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDA09_RS05715	COG1360	Flagellar Motor Protein
CDA09_RS05725	COG2201	protein-glutamate methylesterase activity
CDA09_RS05730	COG0835	chemotaxis
CDA09_RS05730	COG0784	Response regulator, receiver
CDA09_RS05735	COG0835	chemotaxis
CDA09_RS05735	COG0784	Response regulator, receiver
CDA09_RS05740	COG0745	RESPONSE REGULATOR receiver
CDA09_RS05745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CDA09_RS05750	COG2198	Histidine kinase
CDA09_RS05750	COG0643	Histidine kinase
CDA09_RS05750	COG0784	Response regulator, receiver
CDA09_RS05755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDA09_RS05760	COG0564	pseudouridine synthase activity
CDA09_RS05765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDA09_RS05770	COG0583	DNA-binding transcription factor activity
CDA09_RS05775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDA09_RS05780	COG4208	sulfate ABC transporter
CDA09_RS05785	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDA09_RS05860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDA09_RS05865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDA09_RS05870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDA09_RS05890	COG2814	Major facilitator Superfamily
CDA09_RS05930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDA09_RS05935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDA09_RS05940	COG1570	exodeoxyribonuclease VII activity
CDA09_RS05945	COG0811	peptide transport
CDA09_RS05950	COG0848	biopolymer transport protein
CDA09_RS05955	COG1663	tetraacyldisaccharide 4'-kinase activity
CDA09_RS05960	COG2835	tetraacyldisaccharide 4'-kinase activity
CDA09_RS05965	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDA09_RS05970	COG0563	adenylate kinase activity
CDA09_RS05975	COG0205	6-phosphofructokinase activity
CDA09_RS05995	COG0268	Binds directly to 16S ribosomal RNA
CDA09_RS06005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDA09_RS06010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDA09_RS06015	COG0137	argininosuccinate synthase activity
CDA09_RS06025	COG3123	guanosine phosphorylase activity
CDA09_RS06030	COG1666	GTP binding
CDA09_RS06035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDA09_RS06040	COG1127	ABC transporter
CDA09_RS06060	COG0335	large ribosomal subunit rRNA binding
CDA09_RS06065	COG0336	Belongs to the RNA methyltransferase TrmD family
CDA09_RS06070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDA09_RS06075	COG0228	four-way junction DNA binding
CDA09_RS06085	COG1295	ribonuclease BN
CDA09_RS06100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS06115	COG1858	cytochrome C peroxidase
CDA09_RS06135	COG1183	phosphatidylcholine synthase activity
CDA09_RS06140	COG0688	phosphatidylethanolamine metabolic process
CDA09_RS06145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDA09_RS06155	COG0028	Belongs to the TPP enzyme family
CDA09_RS06180	COG0308	aminopeptidase N
CDA09_RS06190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDA09_RS06195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDA09_RS06200	COG1428	Deoxynucleoside kinase
CDA09_RS06215	COG0617	tRNA 3'-terminal CCA addition
CDA09_RS06225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDA09_RS06230	COG0628	permease
CDA09_RS06235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDA09_RS06245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDA09_RS06255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDA09_RS06270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDA09_RS06280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDA09_RS06310	COG0745	RESPONSE REGULATOR receiver
CDA09_RS06315	COG2205	protein histidine kinase activity
CDA09_RS06320	COG2733	membrane
CDA09_RS06345	COG1785	Belongs to the alkaline phosphatase family
CDA09_RS06355	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDA09_RS06360	COG0004	ammonium transporteR
CDA09_RS06365	COG0697	spore germination
CDA09_RS06370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDA09_RS06375	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDA09_RS06385	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDA09_RS06390	COG0438	transferase activity, transferring glycosyl groups
CDA09_RS06390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDA09_RS06405	COG0651	ATP synthesis coupled electron transport
CDA09_RS06410	COG0650	Formate hydrogenlyase subunit 4
CDA09_RS06420	COG0651	ATP synthesis coupled electron transport
CDA09_RS06425	COG0649	NAD binding
CDA09_RS06430	COG3260	NADH ubiquinone oxidoreductase 20
CDA09_RS06435	COG2259	Doxx family
CDA09_RS06440	COG0469	pyruvate kinase activity
CDA09_RS06455	COG2084	Dehydrogenase
CDA09_RS06460	COG3622	Belongs to the hyi family
CDA09_RS06465	COG3960	tartronate-semialdehyde synthase activity
CDA09_RS06495	COG2201	protein-glutamate methylesterase activity
CDA09_RS06510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS06520	COG4974	Belongs to the 'phage' integrase family
CDA09_RS06525	COG0517	IMP dehydrogenase activity
CDA09_RS06535	COG0583	DNA-binding transcription factor activity
CDA09_RS06545	COG3409	Peptidoglycan-binding domain 1 protein
CDA09_RS06545	COG3267	Type II secretory pathway component ExeA
CDA09_RS06575	COG1132	(ABC) transporter
CDA09_RS06580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDA09_RS06590	COG0765	amino acid transport
CDA09_RS06595	COG0765	amino acid transport
CDA09_RS06600	COG1126	abc transporter atp-binding protein
CDA09_RS06715	COG1815	bacterial-type flagellum-dependent cell motility
CDA09_RS06720	COG1558	bacterial-type flagellum-dependent cell motility
CDA09_RS06725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDA09_RS06735	COG4787	bacterial-type flagellum-dependent cell motility
CDA09_RS06745	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CDA09_RS06750	COG1706	bacterial-type flagellum-dependent cell motility
CDA09_RS06800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDA09_RS06820	COG1157	protein secretion by the type III secretion system
CDA09_RS06835	COG1766	The M ring may be actively involved in energy transduction
CDA09_RS06850	COG1677	Flagellar hook-basal body complex protein FliE
CDA09_RS06855	COG2205	protein histidine kinase activity
CDA09_RS06855	COG0784	Response regulator, receiver
CDA09_RS06855	COG2198	Histidine kinase
CDA09_RS06860	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CDA09_RS06865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDA09_RS06885	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDA09_RS06890	COG1334	flagellar protein FlaG
CDA09_RS06905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDA09_RS06910	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDA09_RS06915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CDA09_RS06930	COG4566	intracellular signal transduction
CDA09_RS06950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDA09_RS06955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDA09_RS06960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDA09_RS06965	COG0009	L-threonylcarbamoyladenylate synthase
CDA09_RS07000	COG4691	Plasmid stability protein
CDA09_RS07030	COG2151	metal-sulfur cluster biosynthetic enzyme
CDA09_RS07040	COG2862	Uncharacterized protein family, UPF0114
CDA09_RS07045	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDA09_RS07055	COG0052	Belongs to the universal ribosomal protein uS2 family
CDA09_RS07060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDA09_RS07065	COG0528	UMP kinase activity
CDA09_RS07070	COG0233	cytoplasmic translational termination
CDA09_RS07075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDA09_RS07080	COG0575	Belongs to the CDS family
CDA09_RS07085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDA09_RS07105	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDA09_RS07110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDA09_RS07115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDA09_RS07120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDA09_RS07125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDA09_RS07135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDA09_RS07140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDA09_RS07145	COG2226	methyltransferase
CDA09_RS07150	COG2267	carboxylic ester hydrolase activity
CDA09_RS07155	COG0156	8-amino-7-oxononanoate synthase activity
CDA09_RS07165	COG3022	response to hydroperoxide
CDA09_RS07170	COG2866	Carboxypeptidase
CDA09_RS07175	COG0560	Phosphoserine phosphatase
CDA09_RS07180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDA09_RS07185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDA09_RS07190	COG1773	rubredoxin
CDA09_RS07220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CDA09_RS07245	COG4263	nitrous-oxide reductase activity
CDA09_RS07255	COG2197	response regulator
CDA09_RS07260	COG3850	Histidine kinase
CDA09_RS07265	COG2181	nitrate reductase activity
CDA09_RS07270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CDA09_RS07275	COG1140	nitrate reductase beta subunit
CDA09_RS07280	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDA09_RS07320	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDA09_RS07345	COG0587	DNA-directed DNA polymerase activity
CDA09_RS07350	COG1671	Belongs to the UPF0178 family
CDA09_RS07360	COG0534	Mate efflux family protein
CDA09_RS07405	COG4447	cellulose binding
CDA09_RS07430	COG0604	alcohol dehydrogenase
CDA09_RS07430	COG3321	synthase
CDA09_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS07465	COG1024	Enoyl-CoA hydratase
CDA09_RS07470	COG1881	PFAM PEBP family protein
CDA09_RS07600	COG1301	dicarboxylic acid transport
CDA09_RS07610	COG4191	Histidine kinase
CDA09_RS07635	COG2205	protein histidine kinase activity
CDA09_RS07640	COG0784	Response regulator, receiver
CDA09_RS07645	COG4585	Histidine kinase
CDA09_RS07650	COG2197	response regulator
CDA09_RS07660	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS07675	COG4191	Histidine kinase
CDA09_RS07685	COG2204	response regulator
CDA09_RS07690	COG1100	Small GTP-binding protein
CDA09_RS07695	COG4191	Histidine kinase
CDA09_RS07700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDA09_RS07720	COG4566	intracellular signal transduction
CDA09_RS07730	COG0071	Belongs to the small heat shock protein (HSP20) family
CDA09_RS07745	COG4772	TonB-dependent receptor
CDA09_RS07765	COG0039	L-malate dehydrogenase activity
CDA09_RS07785	COG0386	Belongs to the glutathione peroxidase family
CDA09_RS07790	COG0625	glutathione transferase activity
CDA09_RS07805	COG3851	Histidine kinase
CDA09_RS07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDA09_RS07870	COG4191	Histidine kinase
CDA09_RS07880	COG3158	transport of potassium into the cell
CDA09_RS07895	COG1999	signal sequence binding
CDA09_RS07910	COG3284	Transcriptional regulator
CDA09_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS07940	COG1131	(ABC) transporter
CDA09_RS07980	COG3284	Transcriptional regulator
CDA09_RS07990	COG2414	aldehyde ferredoxin oxidoreductase
CDA09_RS07995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDA09_RS08015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDA09_RS08020	COG0583	DNA-binding transcription factor activity
CDA09_RS08025	COG0702	epimerase
CDA09_RS08030	COG3038	cytochrome b561
CDA09_RS08035	COG2353	YceI-like domain
CDA09_RS08100	COG0315	cyclic pyranopterin monophosphate synthase activity
CDA09_RS08110	COG0425	Belongs to the sulfur carrier protein TusA family
CDA09_RS08115	COG0525	valine-tRNA ligase activity
CDA09_RS08130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDA09_RS08135	COG0795	lipopolysaccharide-transporting ATPase activity
CDA09_RS08155	COG1959	2 iron, 2 sulfur cluster binding
CDA09_RS08165	COG2814	Major facilitator Superfamily
CDA09_RS08170	COG0583	DNA-binding transcription factor activity
CDA09_RS08175	COG0564	pseudouridine synthase activity
CDA09_RS08230	COG1192	Involved in chromosome partitioning
CDA09_RS08270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDA09_RS08290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDA09_RS08335	COG5554	nitrogen fixation
CDA09_RS08340	COG5554	nitrogen fixation
CDA09_RS08350	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CDA09_RS08365	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDA09_RS08370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDA09_RS08385	COG5420	small protein containing a coiled-coil domain
CDA09_RS08415	COG0583	DNA-binding transcription factor activity
CDA09_RS08420	COG1295	ribonuclease BN
CDA09_RS08430	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CDA09_RS08455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDA09_RS08465	COG0683	leucine binding
CDA09_RS08475	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDA09_RS08540	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDA09_RS08550	COG3842	ATPase activity
CDA09_RS08585	COG1953	Uracil, thiamine, allantoin
CDA09_RS08605	COG0583	DNA-binding transcription factor activity
CDA09_RS08610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDA09_RS08625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDA09_RS08625	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS08630	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS08635	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDA09_RS08650	COG2271	Major facilitator Superfamily
CDA09_RS08680	COG0513	Belongs to the DEAD box helicase family
CDA09_RS08685	COG1451	nucleotide metabolic process
CDA09_RS08690	COG0166	Belongs to the GPI family
CDA09_RS08720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDA09_RS08725	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CDA09_RS08735	COG0535	radical SAM domain protein
CDA09_RS08745	COG0435	Glutathione S-transferase
CDA09_RS08750	COG2259	Doxx family
CDA09_RS08755	COG0400	carboxylic ester hydrolase activity
CDA09_RS08765	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS08770	COG0183	Belongs to the thiolase family
CDA09_RS08785	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS08800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDA09_RS08820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS08825	COG0837	glucose binding
CDA09_RS08840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDA09_RS08880	COG2010	Cytochrome c
CDA09_RS08910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS08920	COG5002	protein histidine kinase activity
CDA09_RS08925	COG0745	RESPONSE REGULATOR receiver
CDA09_RS08930	COG5002	protein histidine kinase activity
CDA09_RS08930	COG2176	DNA-directed DNA polymerase activity
CDA09_RS08935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDA09_RS08980	COG1140	nitrate reductase beta subunit
CDA09_RS08985	COG0243	molybdopterin cofactor binding
CDA09_RS09025	COG0477	Major facilitator Superfamily
CDA09_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS09085	COG2365	Tyrosine phosphatase family
CDA09_RS09100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDA09_RS09125	COG2086	electron transfer activity
CDA09_RS09135	COG2030	dehydratase
CDA09_RS09150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS09160	COG1024	Enoyl-CoA hydratase
CDA09_RS09180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDA09_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS09200	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09205	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09215	COG2186	Transcriptional regulator
CDA09_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09270	COG2197	response regulator
CDA09_RS09305	COG3436	PFAM IS66 Orf2 family protein
CDA09_RS09310	COG4372	Transposase
CDA09_RS09370	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09380	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09395	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDA09_RS09445	COG2267	carboxylic ester hydrolase activity
CDA09_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09470	COG0183	Belongs to the thiolase family
CDA09_RS09485	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS09490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS09495	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09505	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS09505	COG1024	Enoyl-CoA hydratase
CDA09_RS09510	COG0183	Belongs to the thiolase family
CDA09_RS09515	COG1309	transcriptional regulator
CDA09_RS09520	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDA09_RS09545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDA09_RS09570	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS09625	COG1024	Enoyl-CoA hydratase
CDA09_RS09630	COG2070	2-Nitropropane dioxygenase
CDA09_RS09635	COG1024	Enoyl-CoA hydratase
CDA09_RS09640	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09645	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09650	COG0183	Belongs to the thiolase family
CDA09_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS09685	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09700	COG2086	electron transfer activity
CDA09_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09725	COG1024	Enoyl-CoA hydratase
CDA09_RS09745	COG1053	succinate dehydrogenase
CDA09_RS09760	COG3657	addiction module killer protein
CDA09_RS09765	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDA09_RS09770	COG0477	Major facilitator Superfamily
CDA09_RS09775	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS09800	COG3608	succinylglutamate desuccinylase aspartoacylase
CDA09_RS09800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDA09_RS09810	COG0488	(ABC) transporter
CDA09_RS09825	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDA09_RS09845	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09850	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS09860	COG1024	Enoyl-CoA hydratase
CDA09_RS09865	COG2852	Protein conserved in bacteria
CDA09_RS09880	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS09890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS09895	COG2070	2-Nitropropane dioxygenase
CDA09_RS09920	COG3177	Filamentation induced by cAMP protein fic
CDA09_RS09930	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS09935	COG2828	Protein conserved in bacteria
CDA09_RS09940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDA09_RS09955	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDA09_RS09960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS09975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS09980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDA09_RS09995	COG1024	Enoyl-CoA hydratase
CDA09_RS10010	COG2814	Major facilitator Superfamily
CDA09_RS10020	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS10020	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDA09_RS10025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS10055	COG1024	Enoyl-CoA hydratase
CDA09_RS10070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS10100	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS10105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDA09_RS10120	COG0247	lactate metabolic process
CDA09_RS10120	COG2181	nitrate reductase activity
CDA09_RS10155	COG0840	transmembrane signaling receptor activity
CDA09_RS10155	COG5278	phosphoserine phosphatase activity
CDA09_RS10165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDA09_RS10170	COG0573	inorganic phosphate transmembrane transporter activity
CDA09_RS10175	COG0581	inorganic phosphate transmembrane transporter activity
CDA09_RS10180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDA09_RS10230	COG4566	intracellular signal transduction
CDA09_RS10325	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDA09_RS10330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS10390	COG1944	ATP diphosphatase activity
CDA09_RS10450	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDA09_RS10455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS10465	COG3851	Histidine kinase
CDA09_RS10470	COG2197	response regulator
CDA09_RS10475	COG3396	Phenylacetate-CoA oxygenase
CDA09_RS10480	COG3460	Phenylacetate-CoA oxygenase
CDA09_RS10485	COG3396	Phenylacetate-CoA oxygenase
CDA09_RS10490	COG2151	metal-sulfur cluster biosynthetic enzyme
CDA09_RS10495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDA09_RS10510	COG0183	Belongs to the thiolase family
CDA09_RS10515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDA09_RS10530	COG0667	Aldo Keto reductase
CDA09_RS10540	COG0589	response to stress
CDA09_RS10570	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDA09_RS10605	COG0463	Glycosyl transferase, family 2
CDA09_RS10620	COG2391	methyltransferase activity
CDA09_RS10660	COG1595	DNA-templated transcription, initiation
CDA09_RS10670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CDA09_RS10685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDA09_RS10705	COG0789	Transcriptional regulator
CDA09_RS10765	COG2226	methyltransferase
CDA09_RS10775	COG0573	inorganic phosphate transmembrane transporter activity
CDA09_RS10780	COG0573	inorganic phosphate transmembrane transporter activity
CDA09_RS10785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDA09_RS10795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDA09_RS10845	COG0745	RESPONSE REGULATOR receiver
CDA09_RS10860	COG0784	Response regulator, receiver
CDA09_RS10870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDA09_RS10875	COG5598	trimethylamine methyltransferase
CDA09_RS10900	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS10900	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDA09_RS10905	COG2181	nitrate reductase activity
CDA09_RS10905	COG0247	lactate metabolic process
CDA09_RS10910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDA09_RS10925	COG2113	Glycine betaine
CDA09_RS10930	COG4175	Glycine betaine
CDA09_RS10945	COG4638	Rieske (2fe-2S)
CDA09_RS10965	COG2814	Major facilitator Superfamily
CDA09_RS10995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDA09_RS11010	COG1396	sequence-specific DNA binding
CDA09_RS11025	COG5598	trimethylamine methyltransferase
CDA09_RS11035	COG0583	DNA-binding transcription factor activity
CDA09_RS11040	COG4638	Rieske (2fe-2S)
CDA09_RS11050	COG4176	ABC-type proline glycine betaine transport system permease component
CDA09_RS11055	COG2113	Glycine betaine
CDA09_RS11065	COG4977	sequence-specific DNA binding
CDA09_RS11070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDA09_RS11075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDA09_RS11080	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS11085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDA09_RS11085	COG1017	nitric oxide dioxygenase activity
CDA09_RS11100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDA09_RS11110	COG5012	cobalamin binding
CDA09_RS11145	COG0477	Major facilitator Superfamily
CDA09_RS11150	COG0583	DNA-binding transcription factor activity
CDA09_RS11155	COG0583	DNA-binding transcription factor activity
CDA09_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS11175	COG0583	DNA-binding transcription factor activity
CDA09_RS11195	COG5012	cobalamin binding
CDA09_RS11200	COG1410	methionine synthase
CDA09_RS11200	COG0646	methionine synthase
CDA09_RS11215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDA09_RS11220	COG1760	l-serine dehydratase
CDA09_RS11270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDA09_RS11275	COG2011	ABC-type metal ion transport system permease component
CDA09_RS11285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDA09_RS11305	COG0702	epimerase
CDA09_RS11315	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
CDA09_RS11320	COG0189	ligase activity
CDA09_RS11330	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
CDA09_RS11340	COG3284	Transcriptional regulator
CDA09_RS11350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDA09_RS11390	COG1538	Outer membrane efflux protein
CDA09_RS11395	COG0745	RESPONSE REGULATOR receiver
CDA09_RS11400	COG2205	protein histidine kinase activity
CDA09_RS11415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDA09_RS11440	COG0697	spore germination
CDA09_RS11470	COG2010	Cytochrome c
CDA09_RS11520	COG1229	Formylmethanofuran dehydrogenase subunit A
CDA09_RS11550	COG0019	diaminopimelate decarboxylase activity
CDA09_RS11555	COG0302	gtp cyclohydrolase
CDA09_RS11560	COG0583	DNA-binding transcription factor activity
CDA09_RS11570	COG4451	ribulose bisphosphate carboxylase, small
CDA09_RS11580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDA09_RS11585	COG3954	Phosphoribulokinase
CDA09_RS11590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDA09_RS11595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDA09_RS11600	COG0126	phosphoglycerate kinase activity
CDA09_RS11605	COG0191	fructose-bisphosphate aldolase activity
CDA09_RS11635	COG3842	ATPase activity
CDA09_RS11645	COG0395	ABC-type sugar transport system, permease component
CDA09_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS11675	COG0798	PFAM Bile acid sodium symporter
CDA09_RS11680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDA09_RS11690	COG0625	glutathione transferase activity
CDA09_RS11695	COG1063	alcohol dehydrogenase
CDA09_RS11725	COG1942	4-Oxalocrotonate Tautomerase
CDA09_RS11730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDA09_RS11735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDA09_RS11745	COG1773	rubredoxin
CDA09_RS11750	COG1024	Enoyl-CoA hydratase
CDA09_RS11755	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS11765	COG1846	Transcriptional regulator
CDA09_RS11775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDA09_RS11780	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS11795	COG1024	Enoyl-CoA hydratase
CDA09_RS11800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS11805	COG0183	Belongs to the thiolase family
CDA09_RS11835	COG1522	sequence-specific DNA binding
CDA09_RS11840	COG3108	Peptidase M15
CDA09_RS11845	COG2989	Protein conserved in bacteria
CDA09_RS11890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDA09_RS11900	COG4172	Belongs to the ABC transporter superfamily
CDA09_RS11905	COG1388	LysM domain
CDA09_RS11905	COG0741	lytic transglycosylase activity
CDA09_RS11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS11920	COG0328	RNA-DNA hybrid ribonuclease activity
CDA09_RS11965	COG4251	negative regulation of phosphorylation
CDA09_RS11965	COG3706	GGDEF domain
CDA09_RS11965	COG5001	Diguanylate cyclase
CDA09_RS11965	COG2203	Gaf domain
CDA09_RS11970	COG0243	molybdopterin cofactor binding
CDA09_RS11980	COG1858	cytochrome C peroxidase
CDA09_RS11985	COG1858	cytochrome C peroxidase
CDA09_RS11990	COG2204	response regulator
CDA09_RS11995	COG4191	Histidine kinase
CDA09_RS12010	COG1858	cytochrome C peroxidase
CDA09_RS12020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDA09_RS12025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDA09_RS12030	COG0450	alkyl hydroperoxide reductase
CDA09_RS12055	COG2363	Small membrane protein
CDA09_RS12060	COG2814	Major facilitator Superfamily
CDA09_RS12070	COG0411	ABC transporter
CDA09_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS12100	COG1024	Enoyl-CoA hydratase
CDA09_RS12165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDA09_RS12175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDA09_RS12210	COG2133	pyrroloquinoline quinone binding
CDA09_RS12275	COG1966	Carbon starvation protein
CDA09_RS12280	COG2879	small protein
CDA09_RS12285	COG0523	cobalamin synthesis protein
CDA09_RS12300	COG0784	Response regulator, receiver
CDA09_RS12300	COG2205	protein histidine kinase activity
CDA09_RS12300	COG5002	protein histidine kinase activity
CDA09_RS12305	COG2900	Belongs to the SlyX family
CDA09_RS12310	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CDA09_RS12315	COG0477	Major facilitator Superfamily
CDA09_RS12345	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS12350	COG1253	flavin adenine dinucleotide binding
CDA09_RS12355	COG4681	YaeQ
CDA09_RS12365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDA09_RS12370	COG0302	gtp cyclohydrolase
CDA09_RS12380	COG0306	phosphate transporter
CDA09_RS12390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDA09_RS12395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDA09_RS12415	COG0791	NLP P60 protein
CDA09_RS12420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDA09_RS12425	COG0148	phosphopyruvate hydratase activity
CDA09_RS12430	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CDA09_RS12435	COG0504	CTP synthase activity
CDA09_RS12445	COG1335	isochorismatase
CDA09_RS12465	COG0047	phosphoribosylformylglycinamidine synthase activity
CDA09_RS12465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDA09_RS12475	COG0463	Glycosyl transferase, family 2
CDA09_RS12485	COG0671	phosphoesterase, PA-phosphatase related
CDA09_RS12505	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS12505	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDA09_RS12525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDA09_RS12535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDA09_RS12555	COG1136	(ABC) transporter
CDA09_RS12565	COG1620	l-lactate permease
CDA09_RS12590	COG3047	cAMP biosynthetic process
CDA09_RS12610	COG1196	nuclear chromosome segregation
CDA09_RS12625	COG1473	amidohydrolase
CDA09_RS12635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDA09_RS12640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDA09_RS12640	COG2169	Transcriptional regulator
CDA09_RS12645	COG3530	Putative quorum-sensing-regulated virulence factor
CDA09_RS12650	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDA09_RS12665	COG0577	efflux transmembrane transporter activity
CDA09_RS12665	COG1136	(ABC) transporter
CDA09_RS12680	COG1309	transcriptional regulator
CDA09_RS12690	COG0583	DNA-binding transcription factor activity
CDA09_RS12695	COG0477	Major facilitator Superfamily
CDA09_RS12700	COG1573	uracil-dna glycosylase
CDA09_RS12705	COG0456	acetyltransferase
CDA09_RS12710	COG1214	PFAM Peptidase M22, glycoprotease
CDA09_RS12730	COG2917	probably involved in intracellular septation
CDA09_RS12735	COG2350	Protein conserved in bacteria
CDA09_RS12740	COG0271	Belongs to the BolA IbaG family
CDA09_RS12745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDA09_RS12750	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS12765	COG1309	transcriptional regulator
CDA09_RS12770	COG0084	hydrolase, TatD family'
CDA09_RS12790	COG1127	ABC transporter
CDA09_RS12795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDA09_RS12805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDA09_RS12810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDA09_RS12840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDA09_RS12845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDA09_RS12855	COG1355	regulation of microtubule-based process
CDA09_RS12860	COG2078	PFAM AMMECR1 domain protein
CDA09_RS12860	COG3885	ferrous iron binding
CDA09_RS12865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDA09_RS12875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDA09_RS12890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDA09_RS12895	COG4208	sulfate ABC transporter
CDA09_RS12900	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDA09_RS12905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDA09_RS12915	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDA09_RS12925	COG2353	YceI-like domain
CDA09_RS12940	COG0643	Histidine kinase
CDA09_RS12940	COG2198	Histidine kinase
CDA09_RS12945	COG2201	protein-glutamate methylesterase activity
CDA09_RS12955	COG1611	Belongs to the LOG family
CDA09_RS12975	COG2009	succinate dehydrogenase
CDA09_RS12985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDA09_RS12990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDA09_RS12995	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDA09_RS13040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDA09_RS13060	COG4942	peptidase
CDA09_RS13070	COG4680	protein conserved in bacteria
CDA09_RS13075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDA09_RS13075	COG0519	Catalyzes the synthesis of GMP from XMP
CDA09_RS13090	COG2914	Belongs to the UPF0125 (RnfH) family
CDA09_RS13095	COG2867	negative regulation of translational initiation
CDA09_RS13100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDA09_RS13105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDA09_RS13110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDA09_RS13115	COG0601	transmembrane transport
CDA09_RS13130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDA09_RS13135	COG0542	response to heat
CDA09_RS13145	COG0314	molybdopterin synthase activity
CDA09_RS13150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDA09_RS13155	COG0303	'Molybdopterin
CDA09_RS13160	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDA09_RS13170	COG1199	ATP-dependent helicase activity
CDA09_RS13180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDA09_RS13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDA09_RS13190	COG0567	Dehydrogenase, E1 component
CDA09_RS13200	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDA09_RS13205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDA09_RS13210	COG1053	succinate dehydrogenase
CDA09_RS13225	COG2188	Transcriptional regulator
CDA09_RS13230	COG0039	L-malate dehydrogenase activity
CDA09_RS13240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDA09_RS13255	COG1840	ABC-type Fe3 transport system, periplasmic component
CDA09_RS13270	COG1178	ABC-type Fe3 transport system permease component
CDA09_RS13275	COG3842	ATPase activity
CDA09_RS13280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDA09_RS13285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CDA09_RS13290	COG0167	dihydroorotate dehydrogenase activity
CDA09_RS13295	COG4657	Part of a membrane complex involved in electron transport
CDA09_RS13300	COG2878	Part of a membrane complex involved in electron transport
CDA09_RS13310	COG4658	electron transport chain
CDA09_RS13315	COG4659	FMN binding
CDA09_RS13325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDA09_RS13335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDA09_RS13355	COG0326	Molecular chaperone. Has ATPase activity
CDA09_RS13400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDA09_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS13455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDA09_RS13520	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDA09_RS13540	COG2814	Major facilitator Superfamily
CDA09_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS13565	COG1024	Enoyl-CoA hydratase
CDA09_RS13605	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS13610	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDA09_RS13645	COG2223	nitrite transmembrane transporter activity
CDA09_RS13660	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDA09_RS13665	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS13725	COG2086	electron transfer activity
CDA09_RS13735	COG0583	DNA-binding transcription factor activity
CDA09_RS13745	COG4974	Belongs to the 'phage' integrase family
CDA09_RS13750	COG0582	viral genome integration into host DNA
CDA09_RS13755	COG4974	Belongs to the 'phage' integrase family
CDA09_RS13760	COG0517	IMP dehydrogenase activity
CDA09_RS13775	COG4974	Belongs to the 'phage' integrase family
CDA09_RS13780	COG0582	viral genome integration into host DNA
CDA09_RS13785	COG4974	Belongs to the 'phage' integrase family
CDA09_RS13820	COG0302	gtp cyclohydrolase
CDA09_RS13830	COG1024	Enoyl-CoA hydratase
CDA09_RS13835	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS13840	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS13850	COG2124	cytochrome p450
CDA09_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS13880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS13910	COG1233	COG1233 Phytoene dehydrogenase and related
CDA09_RS13935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDA09_RS13980	COG1192	Involved in chromosome partitioning
CDA09_RS14090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDA09_RS14130	COG2003	Belongs to the UPF0758 family
CDA09_RS14170	COG4804	nuclease activity
CDA09_RS14235	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CDA09_RS14270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDA09_RS14280	COG1185	polyribonucleotide nucleotidyltransferase activity
CDA09_RS14285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDA09_RS14290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDA09_RS14295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDA09_RS14300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDA09_RS14305	COG2251	uridine kinase activity
CDA09_RS14305	COG0195	Participates in both transcription termination and antitermination
CDA09_RS14310	COG0779	Required for maturation of 30S ribosomal subunits
CDA09_RS14320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDA09_RS14325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDA09_RS14330	COG0180	Tryptophanyl-tRNA synthetase
CDA09_RS14335	COG1994	Peptidase M50
CDA09_RS14340	COG0009	L-threonylcarbamoyladenylate synthase
CDA09_RS14345	COG0613	PHP domain protein
CDA09_RS14350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDA09_RS14355	COG0509	glycine decarboxylation via glycine cleavage system
CDA09_RS14360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDA09_RS14360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDA09_RS14375	COG1215	transferase activity, transferring glycosyl groups
CDA09_RS14380	COG0583	DNA-binding transcription factor activity
CDA09_RS14405	COG0488	(ABC) transporter
CDA09_RS14410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS14415	COG3263	regulation of cellular component size
CDA09_RS14430	COG0577	efflux transmembrane transporter activity
CDA09_RS14435	COG1136	(ABC) transporter
CDA09_RS14445	COG5001	Diguanylate cyclase
CDA09_RS14445	COG3447	MASE1 domain protein
CDA09_RS14445	COG5002	protein histidine kinase activity
CDA09_RS14460	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CDA09_RS14465	COG4181	ATPase activity
CDA09_RS14475	COG0709	Synthesizes selenophosphate from selenide and ATP
CDA09_RS14480	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CDA09_RS14485	COG2204	response regulator
CDA09_RS14490	COG4191	Histidine kinase
CDA09_RS14495	COG1132	(ABC) transporter
CDA09_RS14510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDA09_RS14510	COG1042	CoA-binding domain protein
CDA09_RS14510	COG0045	succinate-CoA ligase (ADP-forming) activity
CDA09_RS14520	COG2183	response to ionizing radiation
CDA09_RS14525	COG1393	Belongs to the ArsC family
CDA09_RS14535	COG0850	regulation of cytokinetic process
CDA09_RS14545	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDA09_RS14555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDA09_RS14560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CDA09_RS14560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDA09_RS14565	COG4585	Histidine kinase
CDA09_RS14570	COG2197	response regulator
CDA09_RS14600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDA09_RS14600	COG0574	Belongs to the PEP-utilizing enzyme family
CDA09_RS14605	COG0517	IMP dehydrogenase activity
CDA09_RS14615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDA09_RS14630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDA09_RS14660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDA09_RS14675	COG2816	NAD+ diphosphatase activity
CDA09_RS14720	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS14730	COG0183	Belongs to the thiolase family
CDA09_RS14735	COG1024	Enoyl-CoA hydratase
CDA09_RS14740	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS14755	COG0411	ABC transporter
CDA09_RS14765	COG1309	transcriptional regulator
CDA09_RS14775	COG5002	protein histidine kinase activity
CDA09_RS14795	COG0066	3-isopropylmalate dehydratase activity
CDA09_RS14805	COG2151	metal-sulfur cluster biosynthetic enzyme
CDA09_RS14815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDA09_RS14820	COG0719	Fe-S assembly protein
CDA09_RS14825	COG0396	ATPase activity
CDA09_RS14830	COG0719	Fe-S assembly protein
CDA09_RS14835	COG1067	ATP-dependent peptidase activity
CDA09_RS14845	COG1881	PFAM PEBP family protein
CDA09_RS14865	COG2197	response regulator
CDA09_RS14905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDA09_RS14910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDA09_RS14920	COG1196	nuclear chromosome segregation
CDA09_RS14930	COG2171	N-acyltransferase activity
CDA09_RS14940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDA09_RS14955	COG0633	Ferredoxin
CDA09_RS14960	COG0443	Heat shock 70 kDa protein
CDA09_RS14965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CDA09_RS14975	COG0822	iron-sulfur transferase activity
CDA09_RS14980	COG1104	cysteine desulfurase activity
CDA09_RS14985	COG1104	cysteine desulfurase activity
CDA09_RS14995	COG1045	serine acetyltransferase
CDA09_RS15005	COG0483	inositol monophosphate 1-phosphatase activity
CDA09_RS15010	COG0513	Belongs to the DEAD box helicase family
CDA09_RS15110	COG0583	DNA-binding transcription factor activity
CDA09_RS15130	COG4962	Type ii secretion system protein e
CDA09_RS15135	COG3838	Conjugal transfer protein Trbc
CDA09_RS15145	COG3451	type IV secretory pathway VirB4
CDA09_RS15170	COG2948	multi-organism process
CDA09_RS15200	COG0322	excinuclease ABC activity
CDA09_RS15205	COG1472	Belongs to the glycosyl hydrolase 3 family
CDA09_RS15210	COG0736	holo-[acyl-carrier-protein] synthase activity
CDA09_RS15215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDA09_RS15220	COG1381	Involved in DNA repair and RecF pathway recombination
CDA09_RS15225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDA09_RS15230	COG0571	ribonuclease III activity
CDA09_RS15240	COG0681	Belongs to the peptidase S26 family
CDA09_RS15245	COG0481	GTPase activity
CDA09_RS15255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDA09_RS15280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDA09_RS15295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDA09_RS15310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDA09_RS15315	COG0416	fatty acid biosynthetic process
CDA09_RS15320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDA09_RS15325	COG1399	metal-binding, possibly nucleic acid-binding protein
CDA09_RS15330	COG0424	maF-like protein
CDA09_RS15335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDA09_RS15350	COG1530	ribonuclease E activity
CDA09_RS15355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDA09_RS15360	COG0556	nucleotide-excision repair
CDA09_RS15380	COG1067	ATP-dependent peptidase activity
CDA09_RS15390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDA09_RS15405	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDA09_RS15410	COG1473	amidohydrolase
CDA09_RS15425	COG0084	hydrolase, TatD family'
CDA09_RS15440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDA09_RS15445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDA09_RS15525	COG0243	molybdopterin cofactor binding
CDA09_RS15530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDA09_RS15535	COG3327	negative regulation of DNA-templated transcription, initiation
CDA09_RS15540	COG2814	Major facilitator Superfamily
CDA09_RS15550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDA09_RS15555	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS15560	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS15560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDA09_RS15585	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS15610	COG4974	Belongs to the 'phage' integrase family
CDA09_RS15615	COG0517	IMP dehydrogenase activity
CDA09_RS15640	COG2329	Antibiotic biosynthesis monooxygenase
CDA09_RS15645	COG1024	Enoyl-CoA hydratase
CDA09_RS15660	COG1742	UPF0060 membrane protein
CDA09_RS15675	COG2204	response regulator
CDA09_RS15685	COG2814	Major facilitator Superfamily
CDA09_RS15690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS15705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDA09_RS15710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS15730	COG3474	cytochrome
CDA09_RS15735	COG0242	peptide deformylase activity
CDA09_RS15745	COG3145	DNA-N1-methyladenine dioxygenase activity
CDA09_RS15755	COG0776	regulation of translation
CDA09_RS15760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDA09_RS15765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDA09_RS15770	COG0740	serine-type endopeptidase activity
CDA09_RS15775	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDA09_RS15780	COG2766	serine protein kinase
CDA09_RS15790	COG2719	SpoVR family
CDA09_RS15795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDA09_RS15795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDA09_RS15805	COG0697	spore germination
CDA09_RS15825	COG0436	Aminotransferase
CDA09_RS15835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDA09_RS15840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDA09_RS15855	COG0791	NLP P60 protein
CDA09_RS15860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDA09_RS15870	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDA09_RS15890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDA09_RS15895	COG3012	SEC-C Motif Domain Protein
CDA09_RS15920	COG0727	PFAM Uncharacterised protein family (UPF0153)
CDA09_RS15930	COG3318	Belongs to the UPF0149 family
CDA09_RS15930	COG3012	SEC-C Motif Domain Protein
CDA09_RS15945	COG0254	rRNA binding
CDA09_RS15955	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDA09_RS15960	COG0501	Belongs to the peptidase M48B family
CDA09_RS15965	COG1162	GTPase activity
CDA09_RS15970	COG0183	Belongs to the thiolase family
CDA09_RS15975	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDA09_RS15980	COG3384	dioxygenase
CDA09_RS15990	COG1490	D-aminoacyl-tRNA deacylase activity
CDA09_RS16025	COG1027	Aspartate ammonia-lyase
CDA09_RS16040	COG1404	Belongs to the peptidase S8 family
CDA09_RS16045	COG1132	(ABC) transporter
CDA09_RS16070	COG1012	belongs to the aldehyde dehydrogenase family
CDA09_RS16085	COG2409	Drug exporters of the RND superfamily
CDA09_RS16110	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CDA09_RS16150	COG3259	Nickel-dependent hydrogenase
CDA09_RS16155	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
CDA09_RS16160	COG3383	formate dehydrogenase (NAD+) activity
CDA09_RS16165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDA09_RS16170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDA09_RS16180	COG1007	ATP synthesis coupled electron transport
CDA09_RS16195	COG0713	ATP synthesis coupled electron transport
CDA09_RS16205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDA09_RS16210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDA09_RS16215	COG1034	ATP synthesis coupled electron transport
CDA09_RS16230	COG0649	NAD binding
CDA09_RS16235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDA09_RS16240	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDA09_RS16245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDA09_RS16260	COG0149	triose-phosphate isomerase activity
CDA09_RS16265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDA09_RS16275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDA09_RS16280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDA09_RS16290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDA09_RS16295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDA09_RS16300	COG1534	Rna-binding protein
CDA09_RS16305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDA09_RS16310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDA09_RS16315	COG0505	Belongs to the CarA family
CDA09_RS16320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDA09_RS16325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDA09_RS16330	COG0735	belongs to the Fur family
CDA09_RS16335	COG0497	DNA recombination
CDA09_RS16340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDA09_RS16345	COG1420	regulation of RNA biosynthetic process
CDA09_RS16350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDA09_RS16360	COG2815	serine threonine protein kinase
CDA09_RS16360	COG0515	serine threonine protein kinase
CDA09_RS16365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDA09_RS16370	COG0443	Heat shock 70 kDa protein
CDA09_RS16375	COG0484	heat shock protein binding
CDA09_RS16380	COG0215	cysteine-tRNA ligase activity
CDA09_RS16400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDA09_RS16405	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDA09_RS16425	COG0285	dihydrofolate synthase activity
CDA09_RS16430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDA09_RS16435	COG0159	tryptophan synthase activity
CDA09_RS16440	COG0133	tryptophan synthase activity
CDA09_RS16445	COG0135	phosphoribosylanthranilate isomerase activity
CDA09_RS16450	COG0101	tRNA pseudouridine synthase activity
CDA09_RS16470	COG0473	3-isopropylmalate dehydrogenase activity
CDA09_RS16475	COG0066	3-isopropylmalate dehydratase activity
CDA09_RS16480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDA09_RS16490	COG2814	Major facilitator Superfamily
CDA09_RS16495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDA09_RS16500	COG0440	acetolactate synthase activity
CDA09_RS16505	COG0028	Belongs to the TPP enzyme family
CDA09_RS16510	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS16520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDA09_RS16530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDA09_RS16535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS16570	COG0277	FAD linked oxidase domain protein
CDA09_RS16575	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDA09_RS16580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDA09_RS16585	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CDA09_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS16600	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDA09_RS16615	COG0564	pseudouridine synthase activity
CDA09_RS16630	COG2951	lytic endotransglycosylase activity
CDA09_RS16645	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS16655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDA09_RS16670	COG2860	membrane
CDA09_RS16690	COG4657	Part of a membrane complex involved in electron transport
CDA09_RS16695	COG2878	Part of a membrane complex involved in electron transport
CDA09_RS16700	COG4656	Part of a membrane complex involved in electron transport
CDA09_RS16705	COG4658	electron transport chain
CDA09_RS16710	COG4659	FMN binding
CDA09_RS16740	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDA09_RS16745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDA09_RS16755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDA09_RS16760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDA09_RS16765	COG1674	ftsk spoiiie
CDA09_RS16775	COG0492	ferredoxin-NADP+ reductase activity
CDA09_RS16780	COG2840	Smr protein MutS2
CDA09_RS16790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDA09_RS16790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDA09_RS16800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDA09_RS16810	COG2217	Heavy metal translocating P-type atpase
CDA09_RS16825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDA09_RS16830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDA09_RS16840	COG3094	Invasion gene expression up-regulator, SirB
CDA09_RS16850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDA09_RS16855	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDA09_RS16860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDA09_RS16885	COG2010	Cytochrome c
CDA09_RS16900	COG3278	Belongs to the heme-copper respiratory oxidase family
CDA09_RS16910	COG2217	Heavy metal translocating P-type atpase
CDA09_RS16920	COG0494	nUDIX hydrolase
CDA09_RS16930	COG2972	Histidine kinase
CDA09_RS16930	COG0745	RESPONSE REGULATOR receiver
CDA09_RS16965	COG4968	Prepilin-type N-terminal cleavage methylation domain
CDA09_RS16970	COG0588	phosphoglycerate mutase activity
CDA09_RS16985	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS16990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS16995	COG0183	Belongs to the thiolase family
CDA09_RS17010	COG0183	Belongs to the thiolase family
CDA09_RS17025	COG2814	Major facilitator Superfamily
CDA09_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS17040	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS17045	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS17060	COG2130	NADP-dependent
CDA09_RS17065	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS17065	COG1024	Enoyl-CoA hydratase
CDA09_RS17070	COG0183	Belongs to the thiolase family
CDA09_RS17075	COG1024	Enoyl-CoA hydratase
CDA09_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS17090	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS17110	COG2814	Major facilitator Superfamily
CDA09_RS17170	COG2814	Major facilitator Superfamily
CDA09_RS17175	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS17180	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS17185	COG3039	Transposase
CDA09_RS17215	COG0527	aspartate kinase activity
CDA09_RS17230	COG0720	synthase
CDA09_RS17235	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDA09_RS17235	COG3264	Mechanosensitive ion channel
CDA09_RS17240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDA09_RS17245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDA09_RS17245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDA09_RS17255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDA09_RS17260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDA09_RS17300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDA09_RS17305	COG1984	allophanate hydrolase subunit 2
CDA09_RS17310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDA09_RS17315	COG2814	Major facilitator Superfamily
CDA09_RS17320	COG4336	lyase activity
CDA09_RS17340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDA09_RS17360	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDA09_RS17365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDA09_RS17385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDA09_RS17400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CDA09_RS17405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDA09_RS17410	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDA09_RS17415	COG0714	Associated with various cellular activities
CDA09_RS17430	COG2951	lytic endotransglycosylase activity
CDA09_RS17435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDA09_RS17445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDA09_RS17450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDA09_RS17465	COG0776	regulation of translation
CDA09_RS17470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDA09_RS17470	COG0072	phenylalanine-tRNA ligase activity
CDA09_RS17475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDA09_RS17480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDA09_RS17485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDA09_RS17490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDA09_RS17495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDA09_RS17510	COG0535	radical SAM domain protein
CDA09_RS17530	COG3391	amine dehydrogenase activity
CDA09_RS17540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDA09_RS17540	COG1648	precorrin-2 dehydrogenase activity
CDA09_RS17565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CDA09_RS17575	COG0776	regulation of translation
CDA09_RS17585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDA09_RS17590	COG0287	Prephenate dehydrogenase
CDA09_RS17600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CDA09_RS17610	COG0402	S-adenosylhomocysteine deaminase activity
CDA09_RS17620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDA09_RS17670	COG0346	lactoylglutathione lyase activity
CDA09_RS17690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDA09_RS17710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDA09_RS17725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDA09_RS17745	COG0494	nUDIX hydrolase
CDA09_RS17750	COG0071	Belongs to the small heat shock protein (HSP20) family
CDA09_RS17755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDA09_RS17765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDA09_RS17780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDA09_RS17785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CDA09_RS17795	COG1999	signal sequence binding
CDA09_RS17800	COG0109	protoheme IX farnesyltransferase activity
CDA09_RS17830	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CDA09_RS17835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDA09_RS17845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDA09_RS17860	COG0514	ATP-dependent DNA helicase (RecQ)
CDA09_RS17865	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CDA09_RS17870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDA09_RS17890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDA09_RS17905	COG2207	Transcriptional regulator
CDA09_RS17905	COG1917	Cupin 2, conserved barrel domain protein
CDA09_RS17910	COG0443	Heat shock 70 kDa protein
CDA09_RS17950	COG2198	Histidine kinase
CDA09_RS17950	COG0643	Histidine kinase
CDA09_RS17955	COG2201	protein-glutamate methylesterase activity
CDA09_RS17965	COG1522	sequence-specific DNA binding
CDA09_RS17975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDA09_RS17985	COG0134	indole-3-glycerol-phosphate synthase activity
CDA09_RS17990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDA09_RS18005	COG0546	phosphoglycolate phosphatase activity
CDA09_RS18010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDA09_RS18015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDA09_RS18020	COG1234	tRNA 3'-trailer cleavage
CDA09_RS18025	COG1716	ATPase activity
CDA09_RS18030	COG0631	protein serine/threonine phosphatase activity
CDA09_RS18035	COG2423	ornithine cyclodeaminase activity
CDA09_RS18060	COG4566	intracellular signal transduction
CDA09_RS18065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDA09_RS18070	COG0037	tRNA processing
CDA09_RS18075	COG0825	malonyl-CoA metabolic process
CDA09_RS18080	COG1253	flavin adenine dinucleotide binding
CDA09_RS18085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDA09_RS18090	COG0670	Belongs to the BI1 family
CDA09_RS18105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDA09_RS18110	COG0343	queuine tRNA-ribosyltransferase activity
CDA09_RS18115	COG1862	Preprotein translocase
CDA09_RS18120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDA09_RS18125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDA09_RS18130	COG2095	MarC family integral membrane protein
CDA09_RS18145	COG2967	ApaG domain
CDA09_RS18150	COG0784	Response regulator, receiver
CDA09_RS18150	COG4191	Histidine kinase
CDA09_RS18155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDA09_RS18165	COG0653	protein targeting
CDA09_RS18180	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CDA09_RS18185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDA09_RS18195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDA09_RS18200	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDA09_RS18205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDA09_RS18210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDA09_RS18215	COG0772	Belongs to the SEDS family
CDA09_RS18220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDA09_RS18225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDA09_RS18230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDA09_RS18235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDA09_RS18250	COG0275	rRNA processing
CDA09_RS18255	COG2001	Belongs to the MraZ family
CDA09_RS18270	COG0418	dihydroorotase activity
CDA09_RS18280	COG0792	nuclease activity
CDA09_RS18285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDA09_RS18290	COG2823	Periplasmic or secreted lipoprotein
CDA09_RS18295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDA09_RS18310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDA09_RS18320	COG0439	Biotin carboxylase
CDA09_RS18325	COG2264	protein methyltransferase activity
CDA09_RS18340	COG3133	Outer membrane lipoprotein
CDA09_RS18345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDA09_RS18350	COG0537	adenosine 5'-monophosphoramidase activity
CDA09_RS18365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDA09_RS18375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDA09_RS18425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CDA09_RS18430	COG2076	Multidrug Resistance protein
CDA09_RS18470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDA09_RS18485	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CDA09_RS18485	COG0662	Cupin 2, conserved barrel domain protein
CDA09_RS18515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDA09_RS18520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDA09_RS18535	COG1309	transcriptional regulator
CDA09_RS18545	COG2119	membrane
CDA09_RS18550	COG0351	phosphomethylpyrimidine kinase
CDA09_RS18555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDA09_RS18570	COG2022	thiamine diphosphate biosynthetic process
CDA09_RS18580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDA09_RS18590	COG0022	dehydrogenase e1 component
CDA09_RS18595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDA09_RS18615	COG0583	DNA-binding transcription factor activity
CDA09_RS18620	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS18635	COG2610	gluconate transmembrane transporter activity
CDA09_RS18665	COG1968	undecaprenyl-diphosphatase activity
CDA09_RS18670	COG3150	esterase
CDA09_RS18675	COG2226	methyltransferase
CDA09_RS18680	COG2962	Rard protein
CDA09_RS18685	COG0557	exoribonuclease II activity
CDA09_RS18695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDA09_RS18700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDA09_RS18705	COG2239	Acts as a magnesium transporter
CDA09_RS18710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDA09_RS18715	COG0352	thiamine-phosphate diphosphorylase activity
CDA09_RS18755	COG1678	Uncharacterized ACR, COG1678
CDA09_RS18760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDA09_RS18765	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDA09_RS18770	COG0540	Belongs to the ATCase OTCase family
CDA09_RS18780	COG1872	DUF167
CDA09_RS18785	COG0762	integral membrane protein
CDA09_RS18815	COG1981	membrane
CDA09_RS18830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CDA09_RS18835	COG4654	Cytochrome c, class I
CDA09_RS18840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDA09_RS18840	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDA09_RS18855	COG2200	EAL domain
CDA09_RS18865	COG2197	response regulator
CDA09_RS18870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS18875	COG2274	protein secretion by the type I secretion system
CDA09_RS18880	COG0735	belongs to the Fur family
CDA09_RS18885	COG1121	(ABC) transporter
CDA09_RS18900	COG1280	lysine exporter protein (LysE YggA)
CDA09_RS18910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CDA09_RS18920	COG0129	dihydroxy-acid dehydratase activity
CDA09_RS18925	COG3132	Protein of unknown function, DUF480
CDA09_RS18930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDA09_RS18990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS18995	COG1136	(ABC) transporter
CDA09_RS18995	COG0577	efflux transmembrane transporter activity
CDA09_RS19020	COG0672	)-iron permease
CDA09_RS19070	COG5002	protein histidine kinase activity
CDA09_RS19075	COG0745	RESPONSE REGULATOR receiver
CDA09_RS19100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDA09_RS19170	COG4969	Belongs to the N-Me-Phe pilin family
CDA09_RS19180	COG3744	PilT protein domain protein
CDA09_RS19190	COG3609	addiction module antidote protein, CC2985 family
CDA09_RS19250	COG0436	Aminotransferase
CDA09_RS19255	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDA09_RS19260	COG0235	Class ii aldolase
CDA09_RS19265	COG2084	Dehydrogenase
CDA09_RS19270	COG2084	Dehydrogenase
CDA09_RS19275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDA09_RS19285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDA09_RS19290	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDA09_RS19320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDA09_RS19335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDA09_RS19355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDA09_RS19380	COG4647	ligase activity
CDA09_RS19385	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CDA09_RS19390	COG0145	ligase activity
CDA09_RS19395	COG0629	single-stranded DNA binding
CDA09_RS19400	COG2814	Major facilitator Superfamily
CDA09_RS19415	COG0203	ribosomal protein L17
CDA09_RS19420	COG0202	RNA polymerase activity
CDA09_RS19425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDA09_RS19430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDA09_RS19435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDA09_RS19440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDA09_RS19445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDA09_RS19450	COG0201	protein transport
CDA09_RS19455	COG0200	Binds to the 23S rRNA
CDA09_RS19460	COG1841	ribosomal large subunit assembly
CDA09_RS19465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDA09_RS19470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDA09_RS19475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDA09_RS19480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDA09_RS19485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDA09_RS19490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDA09_RS19495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDA09_RS19500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDA09_RS19505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDA09_RS19510	COG0255	Belongs to the universal ribosomal protein uL29 family
CDA09_RS19515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDA09_RS19520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDA09_RS19525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDA09_RS19530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDA09_RS19535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDA09_RS19540	COG0089	rRNA binding
CDA09_RS19545	COG0088	Forms part of the polypeptide exit tunnel
CDA09_RS19550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDA09_RS19555	COG0051	transcription antitermination factor activity, RNA binding
CDA09_RS19560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDA09_RS19565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDA09_RS19570	COG0049	tRNA binding
CDA09_RS19575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDA09_RS19580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDA09_RS19585	COG0085	RNA polymerase activity
CDA09_RS19590	COG0222	ribosome binding
CDA09_RS19595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDA09_RS19600	COG0081	regulation of translation
CDA09_RS19605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDA09_RS19615	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDA09_RS19625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDA09_RS19645	COG0277	FAD linked oxidase domain protein
CDA09_RS19670	COG2198	Histidine kinase
CDA09_RS19670	COG0784	Response regulator, receiver
CDA09_RS19670	COG2205	protein histidine kinase activity
CDA09_RS19685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDA09_RS19700	COG1032	radical SAM domain protein
CDA09_RS19705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDA09_RS19710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDA09_RS19715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDA09_RS19725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDA09_RS19730	COG1116	anion transmembrane transporter activity
CDA09_RS19765	COG1022	Amp-dependent synthetase and ligase
CDA09_RS19800	COG0586	Pfam SNARE associated Golgi protein
CDA09_RS19810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDA09_RS19815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDA09_RS19815	COG1703	isobutyryl-CoA mutase activity
CDA09_RS19815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDA09_RS19825	COG4191	Histidine kinase
CDA09_RS19825	COG0784	Response regulator, receiver
CDA09_RS19855	COG3158	transport of potassium into the cell
CDA09_RS19860	COG0745	RESPONSE REGULATOR receiver
CDA09_RS19865	COG2205	protein histidine kinase activity
CDA09_RS19875	COG2321	neutral zinc metallopeptidase
CDA09_RS19890	COG2197	response regulator
CDA09_RS19900	COG1999	signal sequence binding
CDA09_RS19905	COG2197	response regulator
CDA09_RS19910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDA09_RS19925	COG4770	biotin carboxylase activity
CDA09_RS19930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDA09_RS19935	COG1703	isobutyryl-CoA mutase activity
CDA09_RS19940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDA09_RS19940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDA09_RS19945	COG1802	Transcriptional regulator
CDA09_RS19950	COG0114	fumarate hydratase activity
CDA09_RS19965	COG2197	response regulator
CDA09_RS20010	COG4964	Belongs to the GSP D family
CDA09_RS20060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDA09_RS20065	COG3162	membrane
CDA09_RS20070	COG1024	Enoyl-CoA hydratase
CDA09_RS20075	COG1492	cobalamin metabolic process
CDA09_RS20080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDA09_RS20090	COG1242	4 iron, 4 sulfur cluster binding
CDA09_RS20095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDA09_RS20105	COG0513	Belongs to the DEAD box helicase family
CDA09_RS20130	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDA09_RS20175	COG0427	acetyl-CoA hydrolase
CDA09_RS20180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDA09_RS20185	COG0019	diaminopimelate decarboxylase activity
CDA09_RS20220	COG0583	DNA-binding transcription factor activity
CDA09_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS20230	COG1280	lysine exporter protein (LysE YggA)
CDA09_RS20245	COG0545	Peptidyl-prolyl cis-trans isomerase
CDA09_RS20265	COG3038	cytochrome b561
CDA09_RS20280	COG0671	phosphoesterase, PA-phosphatase related
CDA09_RS20285	COG0671	phosphoesterase, PA-phosphatase related
CDA09_RS20310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDA09_RS20325	COG0493	'glutamate synthase
CDA09_RS20335	COG0069	glutamate synthase activity
CDA09_RS20335	COG0070	glutamate synthase
CDA09_RS20335	COG0067	glutamate synthase
CDA09_RS20340	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDA09_RS20345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDA09_RS20350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDA09_RS20385	COG1965	Belongs to the frataxin family
CDA09_RS20435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDA09_RS20440	COG0284	orotidine-5'-phosphate decarboxylase activity
CDA09_RS20450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDA09_RS20455	COG3161	chorismate lyase activity
CDA09_RS20460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDA09_RS20470	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDA09_RS20490	COG1741	Belongs to the pirin family
CDA09_RS20495	COG0778	Nitroreductase
CDA09_RS20535	COG0183	Belongs to the thiolase family
CDA09_RS20540	COG1024	Enoyl-CoA hydratase
CDA09_RS20540	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS20545	COG2067	long-chain fatty acid transport protein
CDA09_RS20550	COG1607	acyl-coa hydrolase
CDA09_RS20555	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS20555	COG1024	Enoyl-CoA hydratase
CDA09_RS20560	COG0183	Belongs to the thiolase family
CDA09_RS20565	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS20570	COG1309	transcriptional regulator
CDA09_RS20585	COG4178	(ABC) transporter
CDA09_RS20595	COG0366	Alpha amylase catalytic
CDA09_RS20605	COG5265	(ABC) transporter
CDA09_RS20615	COG0252	asparaginase activity
CDA09_RS20620	COG0583	DNA-binding transcription factor activity
CDA09_RS20625	COG0730	response to heat
CDA09_RS20640	COG0175	sulfate reduction
CDA09_RS20645	COG0175	sulfate reduction
CDA09_RS20650	COG2895	sulfate adenylyltransferase (ATP) activity
CDA09_RS20665	COG0330	HflC and HflK could
CDA09_RS20670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDA09_RS20675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDA09_RS20685	COG0824	Thioesterase
CDA09_RS20705	COG0823	Involved in the tonB-independent uptake of proteins
CDA09_RS20710	COG2885	chlorophyll binding
CDA09_RS20720	COG0602	queuosine metabolic process
CDA09_RS20725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDA09_RS20735	COG2204	response regulator
CDA09_RS20805	COG3300	MHYT domain
CDA09_RS20805	COG5001	Diguanylate cyclase
CDA09_RS20810	COG0318	PFAM AMP-dependent synthetase and ligase
CDA09_RS20835	COG4214	carbohydrate transport
CDA09_RS20845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDA09_RS20850	COG1546	Belongs to the CinA family
CDA09_RS20855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDA09_RS20860	COG2137	regulation of response to DNA damage stimulus
CDA09_RS20865	COG1137	ATPase activity
CDA09_RS20870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDA09_RS20875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDA09_RS20885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDA09_RS20890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDA09_RS20895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDA09_RS20900	COG0741	lytic transglycosylase activity
CDA09_RS20915	COG0617	tRNA 3'-terminal CCA addition
CDA09_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS20945	COG0037	tRNA processing
CDA09_RS20955	COG1238	metal cluster binding
CDA09_RS20960	COG0251	oxidation-reduction process
CDA09_RS20975	COG0243	molybdopterin cofactor binding
CDA09_RS20985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDA09_RS20990	COG0708	Exodeoxyribonuclease III
CDA09_RS21010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDA09_RS21020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CDA09_RS21050	COG1203	CRISPR-associated helicase, Cas3
CDA09_RS21065	COG1857	crispr-associated protein
CDA09_RS21090	COG1518	maintenance of DNA repeat elements
CDA09_RS21095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDA09_RS21110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDA09_RS21130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDA09_RS21140	COG0861	Integral membrane protein TerC family
CDA09_RS21160	COG3876	Protein conserved in bacteria
CDA09_RS21170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDA09_RS21240	COG2814	Major facilitator Superfamily
CDA09_RS21245	COG0606	chelatase, subunit chli
CDA09_RS21260	COG0347	Belongs to the P(II) protein family
CDA09_RS21265	COG0004	ammonium transporteR
CDA09_RS21280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDA09_RS21285	COG0488	(ABC) transporter
CDA09_RS21305	COG0189	ligase activity
CDA09_RS21315	COG0732	type I restriction modification DNA specificity domain
CDA09_RS21315	COG0827	DNA restriction-modification system
CDA09_RS21335	COG1561	YicC-like family, N-terminal region
CDA09_RS21340	COG2815	serine threonine protein kinase
CDA09_RS21340	COG0515	serine threonine protein kinase
CDA09_RS21345	COG0631	protein serine/threonine phosphatase activity
CDA09_RS21350	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDA09_RS21355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDA09_RS21360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDA09_RS21365	COG0616	signal peptide processing
CDA09_RS21370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDA09_RS21375	COG2022	thiamine diphosphate biosynthetic process
CDA09_RS21390	COG0582	viral genome integration into host DNA
CDA09_RS21400	COG1396	sequence-specific DNA binding
CDA09_RS21405	COG0583	DNA-binding transcription factor activity
CDA09_RS21425	COG3436	PFAM IS66 Orf2 family protein
CDA09_RS21430	COG4372	Transposase
CDA09_RS21435	COG3012	SEC-C Motif Domain Protein
CDA09_RS21440	COG2267	carboxylic ester hydrolase activity
CDA09_RS21455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDA09_RS21460	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDA09_RS21470	COG0346	lactoylglutathione lyase activity
CDA09_RS21485	COG2146	nitrite reductase [NAD(P)H] activity
CDA09_RS21505	COG1802	Transcriptional regulator
CDA09_RS21535	COG1733	regulation of RNA biosynthetic process
CDA09_RS21555	COG1902	pentaerythritol trinitrate reductase activity
CDA09_RS21560	COG0842	Transport permease protein
CDA09_RS21565	COG0842	Transport permease protein
CDA09_RS21565	COG1129	ABC transporter
CDA09_RS21570	COG0842	Transport permease protein
CDA09_RS21570	COG1129	ABC transporter
CDA09_RS21575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS21590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDA09_RS21595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDA09_RS21605	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDA09_RS21610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDA09_RS21685	COG2003	Belongs to the UPF0758 family
CDA09_RS21750	COG2814	Major facilitator Superfamily
CDA09_RS21760	COG1024	Enoyl-CoA hydratase
CDA09_RS21770	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS21775	COG0427	acetyl-CoA hydrolase
CDA09_RS21780	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS21785	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS21790	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDA09_RS21790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDA09_RS21795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDA09_RS21820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS21825	COG1024	Enoyl-CoA hydratase
CDA09_RS21830	COG0183	Belongs to the thiolase family
CDA09_RS21870	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDA09_RS21880	COG0411	ABC transporter
CDA09_RS21895	COG1309	transcriptional regulator
CDA09_RS21985	COG1881	PFAM PEBP family protein
CDA09_RS21990	COG1024	Enoyl-CoA hydratase
CDA09_RS22015	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS22020	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS22110	COG0776	regulation of translation
CDA09_RS22140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDA09_RS22190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDA09_RS22235	COG1192	Involved in chromosome partitioning
CDA09_RS22255	COG2032	superoxide dismutase activity
CDA09_RS22260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDA09_RS22265	COG1194	a g-specific adenine glycosylase
CDA09_RS22275	COG0163	prenyltransferase activity
CDA09_RS22295	COG2860	membrane
CDA09_RS22300	COG1970	mechanosensitive ion channel activity
CDA09_RS22305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDA09_RS22310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CDA09_RS22370	COG1215	transferase activity, transferring glycosyl groups
CDA09_RS22375	COG1649	PFAM Uncharacterised BCR, COG1649
CDA09_RS22375	COG0726	polysaccharide deacetylase
CDA09_RS22475	COG4633	Protein conserved in bacteria
CDA09_RS22480	COG0672	)-iron permease
CDA09_RS22495	COG3383	formate dehydrogenase (NAD+) activity
CDA09_RS22505	COG0583	DNA-binding transcription factor activity
CDA09_RS22515	COG3040	lipid binding
CDA09_RS22535	COG1846	Transcriptional regulator
CDA09_RS22540	COG1538	Outer membrane efflux protein
CDA09_RS22545	COG1566	PFAM secretion protein HlyD family protein
CDA09_RS22560	COG2197	response regulator
CDA09_RS22570	COG2336	PFAM SpoVT AbrB
CDA09_RS22585	COG4453	Protein conserved in bacteria
CDA09_RS22625	COG1309	transcriptional regulator
CDA09_RS22630	COG1024	Enoyl-CoA hydratase
CDA09_RS22635	COG1024	Enoyl-CoA hydratase
CDA09_RS22640	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS22665	COG1960	acyl-CoA dehydrogenase activity
CDA09_RS22670	COG1028	Short-chain dehydrogenase reductase Sdr
CDA09_RS22675	COG3048	D-serine ammonia-lyase activity
CDA09_RS22705	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDA09_RS22710	COG1773	rubredoxin
CDA09_RS22735	COG0411	ABC transporter
CDA09_RS22770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDA09_RS22795	COG0840	transmembrane signaling receptor activity
CDA09_RS22825	COG0826	peptidase U32
CDA09_RS22830	COG0488	(ABC) transporter
CDA09_RS22835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDA09_RS22840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDA09_RS22845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDA09_RS22850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDA09_RS22865	COG2814	Major facilitator Superfamily
CDA09_RS22880	COG0840	transmembrane signaling receptor activity
CDA09_RS22895	COG2258	MOSC domain
CDA09_RS22920	COG0309	Hydrogenase expression formation protein (HypE)
CDA09_RS22925	COG0409	Hydrogenase expression formation protein
CDA09_RS22930	COG0298	carbon dioxide binding
CDA09_RS22935	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CDA09_RS22945	COG0375	protein maturation
CDA09_RS22955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDA09_RS22960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDA09_RS22975	COG0830	nickel cation binding
CDA09_RS22980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CDA09_RS22985	COG0804	urea catabolic process
CDA09_RS22990	COG0832	Belongs to the urease beta subunit family
CDA09_RS22995	COG0831	urea catabolic process
CDA09_RS23000	COG0829	nickel cation binding
CDA09_RS23030	COG0840	transmembrane signaling receptor activity
CDA09_RS23035	COG2204	response regulator
CDA09_RS23040	COG5000	phosphorelay sensor kinase activity
CDA09_RS23050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDA09_RS23055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDA09_RS23060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDA09_RS23065	COG0706	membrane insertase activity
CDA09_RS23070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDA09_RS23075	COG0594	ribonuclease P activity