locus-tag	class	description
G3580_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G3580_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G3580_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G3580_RS00070	ENOG4105C9B	Cysteine desulfurase
G3580_RS00080	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
G3580_RS00085	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
G3580_RS00095	ENOG4105C3K	feS assembly ATPase SufC
G3580_RS00100	ENOG4105JRK	feS assembly protein SufD
G3580_RS00110	ENOG4108UNV	SUF system FeS assembly protein, NifU family
G3580_RS00115	ENOG4105VG1	fes assembly suf system protein
G3580_RS00130	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G3580_RS00135	ENOG4105CPQ	Dehydrogenase
G3580_RS00140	ENOG4105HKX	acetone carboxylase, gamma subunit
G3580_RS00145	ENOG4107TYC	hydantoinase B oxoprolinase
G3580_RS00150	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
G3580_RS00165	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G3580_RS00170	ENOG4105I7I	quinohemoprotein amine dehydrogenase gamma subunit
G3580_RS00185	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G3580_RS00205	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G3580_RS00210	ENOG4105ETT	transcriptional Regulator, LysR family
G3580_RS00230	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
G3580_RS00235	ENOG4105CNV	Aldolase
G3580_RS00240	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G3580_RS00250	ENOG4108KSA	LysR family transcriptional regulator
G3580_RS00265	ENOG4105E4C	Lytic transglycosylase catalytic
G3580_RS00285	ENOG4108VAU	general secretion pathway protein G
G3580_RS00290	ENOG4105D7Q	type ii secretion system
G3580_RS00295	ENOG4107QHF	type ii secretion system protein e
G3580_RS00320	ENOG4105GVR	general secretion pathway protein D
G3580_RS00330	ENOG4108VAU	general secretion pathway protein G
G3580_RS00370	ENOG4105E02	MotA TolQ exbB proton channel
G3580_RS00375	ENOG4105M8F	Biopolymer transport protein exbD tolR
G3580_RS00380	ENOG4105SG9	biopolymer transport protein, ExbD
G3580_RS00425	ENOG41090U3	tautomerase
G3580_RS00435	ENOG4105JQZ	Methyltransferase
G3580_RS00515	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
G3580_RS00525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS00530	ENOG4105BZU	Histidine kinase
G3580_RS00550	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G3580_RS00555	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G3580_RS00575	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
G3580_RS00595	ENOG4105CHR	reductase
G3580_RS00625	ENOG4105BZU	Histidine kinase
G3580_RS00630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS00640	ENOG41061AI	Protein of unknown function (DUF2905)
G3580_RS00650	ENOG4105CS6	Rhs element vgr protein
G3580_RS00690	ENOG4105XFK	Ferrous iron transport protein A
G3580_RS00695	ENOG4105E0Y	RtcB Protein
G3580_RS00720	ENOG4108WF3	methyltransferase
G3580_RS00785	ENOG4107QX8	SPFH domain, Band 7 family protein
G3580_RS00800	ENOG4105DSE	periplasmic solute binding protein
G3580_RS00805	ENOG4105CC5	ABC transporter
G3580_RS00810	ENOG4105DIK	(ABC) transporter
G3580_RS00850	ENOG4105CKI	cobalamin synthesis protein
G3580_RS00860	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G3580_RS00875	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G3580_RS00885	ENOG4105C0H	protease
G3580_RS00890	ENOG4105C5Q	Transcriptional regulator
G3580_RS00905	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G3580_RS00910	ENOG4108RPN	Protein smg homolog
G3580_RS00915	ENOG4105C79	DNA protecting protein DprA
G3580_RS00920	ENOG4108WZM	domain protein
G3580_RS00925	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G3580_RS00930	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G3580_RS00935	ENOG4105D0M	Protease HtpX homolog
G3580_RS00940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS00945	ENOG4105BZU	Histidine kinase
G3580_RS00965	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G3580_RS00970	ENOG4105QAX	Iron-sulfur
G3580_RS00985	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G3580_RS00990	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G3580_RS01005	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS01010	ENOG4105DZG	Dehydrogenase
G3580_RS01020	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
G3580_RS01025	ENOG4108KPJ	rna polymerase sigma factor
G3580_RS01035	ENOG4105DEN	Luciferase family
G3580_RS01040	ENOG4106032	Glutathionylspermidine synthase
G3580_RS01045	ENOG4108RG0	uracil-dna glycosylase
G3580_RS01065	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
G3580_RS01080	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G3580_RS01085	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G3580_RS01090	ENOG4107QJE	Chromosome Partitioning Protein
G3580_RS01095	ENOG4105FA0	parb-like partition protein
G3580_RS01105	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
G3580_RS01110	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G3580_RS01115	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G3580_RS01120	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G3580_RS01125	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G3580_RS01130	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G3580_RS01135	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G3580_RS01140	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G3580_RS01160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G3580_RS01165	ENOG4105BZU	Histidine kinase
G3580_RS01180	ENOG4105E7A	Glutamine amidotransferase
G3580_RS01195	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G3580_RS01205	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G3580_RS01210	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G3580_RS01230	ENOG4105CJN	penicillin-binding protein
G3580_RS01235	ENOG4105CNI	cell division protein FtsW
G3580_RS01245	ENOG4105DZ1	carboxypeptidase
G3580_RS01250	ENOG4105F0I	Aminotransferase
G3580_RS01255	ENOG4108Z43	UPF0250 protein
G3580_RS01260	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G3580_RS01265	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G3580_RS01285	ENOG4105BZU	Histidine kinase
G3580_RS01325	ENOG4105C4R	Atp-dependent dna helicase
G3580_RS01335	ENOG4105MPD	Cytochrome
G3580_RS01355	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS01360	ENOG4105CHU	acetyl-coa acetyltransferase
G3580_RS01385	ENOG4105EYF	MMPL domain protein
G3580_RS01405	ENOG4107SZ9	Hydantoinase oxoprolinase
G3580_RS01410	ENOG4105RQI	acetone carboxylase gamma subunit
G3580_RS01415	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
G3580_RS01430	ENOG4105CKI	cobalamin synthesis protein
G3580_RS01440	ENOG4105F95	Monooxygenase
G3580_RS01445	ENOG4105DWV	Homoserine O-trans-acetylase
G3580_RS01455	ENOG4105E2S	oxidase) subunit II
G3580_RS01470	ENOG4108V08	YfdX protein
G3580_RS01480	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS01485	ENOG4105BZU	Histidine kinase
G3580_RS01495	ENOG4105C5X	domain protein
G3580_RS01500	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G3580_RS01505	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G3580_RS01515	ENOG4105GR3	Histidine kinase
G3580_RS01545	ENOG4105EZ7	amino acid ABC transporter
G3580_RS01550	ENOG4105DRP	amino acid AbC transporter
G3580_RS01555	ENOG4105CDA	abc transporter atp-binding protein
G3580_RS01565	ENOG4105CEN	a g-specific adenine glycosylase
G3580_RS01605	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G3580_RS01610	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G3580_RS01615	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G3580_RS01620	ENOG4105D07	Signal peptide peptidase, SppA
G3580_RS01630	ENOG4105CSA	Coproporphyrinogen iii oxidase
G3580_RS01635	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G3580_RS01640	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G3580_RS01645	ENOG4108ZF3	Phosphatase
G3580_RS01650	ENOG4107WDG	serine threonine protein kinase
G3580_RS01655	ENOG4105DSJ	YicC domain protein
G3580_RS01670	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G3580_RS01675	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G3580_RS01680	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
G3580_RS01685	ENOG4105EA8	2-Nitropropane dioxygenase
G3580_RS01695	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G3580_RS01710	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G3580_RS01725	ENOG4105CP2	von willebrand factor, type a
G3580_RS01780	ENOG4105C2D	reductase
G3580_RS01795	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G3580_RS01855	ENOG4105BZU	Histidine kinase
G3580_RS01865	ENOG4105D05	Receptor
G3580_RS01880	ENOG4106WR0	acetolactate synthase (large subunit)
G3580_RS01890	ENOG4105M4H	endoribonuclease L-psp
G3580_RS01915	ENOG4105W39	Membrane
G3580_RS01920	ENOG4105C7B	Threonine dehydratase
G3580_RS01940	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G3580_RS01945	ENOG4107SC1	transglycosylase
G3580_RS01955	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G3580_RS01960	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G3580_RS01985	ENOG4105CHR	reductase
G3580_RS01990	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G3580_RS02005	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G3580_RS02010	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G3580_RS02015	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
G3580_RS02020	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G3580_RS02025	ENOG4108IUZ	ABC transporter
G3580_RS02030	ENOG4108004	Modulates RecA activity (By similarity)
G3580_RS02035	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G3580_RS02040	ENOG4107TH8	cina domain protein
G3580_RS02045	ENOG4108ZAI	phosphatidylglycerophosphatase a
G3580_RS02050	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G3580_RS02055	ENOG4105CAQ	asparagine synthetase
G3580_RS02065	ENOG4105DER	m42 family
G3580_RS02075	ENOG4107YIM	Involved in the transcription termination process (By similarity)
G3580_RS02080	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G3580_RS02085	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G3580_RS02100	ENOG4108V1U	phospholipid-binding protein
G3580_RS02105	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
G3580_RS02110	ENOG4105VF7	tolerance protein
G3580_RS02120	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G3580_RS02135	ENOG4105CJ1	ABC, transporter
G3580_RS02140	ENOG4108U78	Glutathione S-transferase
G3580_RS02145	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
G3580_RS02150	ENOG4105NZG	Ferredoxin
G3580_RS02175	ENOG4105CK7	Sodium proline symporter
G3580_RS02180	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G3580_RS02200	ENOG4105C75	arginyL-tRNA synthetase
G3580_RS02215	ENOG4107FW0	short-chain dehydrogenase reductase
G3580_RS02235	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G3580_RS02245	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G3580_RS02265	ENOG4105C1G	acyl-Coa dehydrogenase
G3580_RS02270	ENOG41077A9	carbonic anhydrase
G3580_RS02275	ENOG4105CHU	acetyl-coa acetyltransferase
G3580_RS02280	ENOG4105C1G	acyl-Coa dehydrogenase
G3580_RS02295	ENOG4108URH	decarboxylase
G3580_RS02300	ENOG4107QX3	carboxylase
G3580_RS02320	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS02325	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G3580_RS02340	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G3580_RS02360	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS02370	ENOG4105CH5	extracellular solute-binding protein, family 7
G3580_RS02375	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G3580_RS02395	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
G3580_RS02400	ENOG4105C7F	AcnD-accessory protein PrpF
G3580_RS02410	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
G3580_RS02415	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
G3580_RS02420	ENOG4105C26	Dehydrogenase
G3580_RS02425	ENOG4108MP6	LysR family Transcriptional regulator
G3580_RS02430	ENOG4105BZU	Histidine kinase
G3580_RS02435	ENOG4105EUB	pirin domain protein
G3580_RS02450	ENOG4108SGK	Tetr family transcriptional regulator
G3580_RS02460	ENOG4105CJ1	ABC, transporter
G3580_RS02465	ENOG4107QWP	ABC-2 type transporter
G3580_RS02470	ENOG4107QWP	ABC-2 type transporter
G3580_RS02500	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G3580_RS02505	ENOG4108WUH	Transcriptional regulator, TetR family
G3580_RS02510	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
G3580_RS02535	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
G3580_RS02540	ENOG4107QR9	Iron-sulfur cluster binding protein
G3580_RS02545	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G3580_RS02550	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G3580_RS02560	ENOG4105K8R	UPF0145 protein
G3580_RS02570	ENOG4108594	Permease of the drug metabolite transporter
G3580_RS02575	ENOG4105WP5	
G3580_RS02580	ENOG4105EKT	)-iron permease
G3580_RS02590	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G3580_RS02600	ENOG4105D1S	lipid A biosynthesis
G3580_RS02610	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G3580_RS02620	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G3580_RS02630	ENOG4105DR4	Methyltransferase
G3580_RS02670	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G3580_RS02675	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G3580_RS02690	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
G3580_RS02700	ENOG4105C03	ribonuclease
G3580_RS02705	ENOG4108Z03	MAF-like protein
G3580_RS02710	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G3580_RS02715	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
G3580_RS02720	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G3580_RS02735	ENOG4105CUV	Homoserine Kinase
G3580_RS02745	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS02755	ENOG4105DZG	Dehydrogenase
G3580_RS02765	ENOG4108DY6	Extracellular solute-binding protein family 3
G3580_RS02785	ENOG4108URH	decarboxylase
G3580_RS02790	ENOG4105C2M	dna polymerase I
G3580_RS02815	ENOG4105KT7	mgtC SapB transporter
G3580_RS02820	ENOG4105BZU	Histidine kinase
G3580_RS02840	ENOG4105CVE	Lytic murein transglycosylase
G3580_RS02850	ENOG4107BJW	polysaccharide deacetylase
G3580_RS02855	ENOG4105CG5	Glycosyl transferase (Group 1
G3580_RS02860	ENOG4107TYR	Glycosyl Transferase
G3580_RS02880	ENOG4105CG5	Glycosyl transferase (Group 1
G3580_RS02885	ENOG4105CG5	Glycosyl transferase (Group 1
G3580_RS02890	ENOG4107XU6	Glycosyl transferase (Group 1
G3580_RS02900	ENOG4105BZ1	(ABC) transporter
G3580_RS02910	ENOG4105CVJ	phosphoglycerate mutase
G3580_RS02915	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G3580_RS02920	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G3580_RS02925	ENOG4108YZT	Adenosylcobinamide kinase
G3580_RS02930	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G3580_RS02940	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS02950	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
G3580_RS02955	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G3580_RS02965	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G3580_RS02970	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G3580_RS02980	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G3580_RS02985	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G3580_RS02995	ENOG4105M8F	Biopolymer transport protein exbD tolR
G3580_RS03000	ENOG4105E02	MotA TolQ exbB proton channel
G3580_RS03005	ENOG4107YD3	Thioesterase
G3580_RS03015	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G3580_RS03020	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G3580_RS03040	ENOG4105DC8	reductase
G3580_RS03045	ENOG4105CKW	Inner membrane protein yedI
G3580_RS03055	ENOG4105EJ9	Membrane
G3580_RS03080	ENOG4105EW9	transcriptional regulator AsnC family
G3580_RS03085	ENOG4105CIK	Amidinotransferase
G3580_RS03090	ENOG4107QWB	Ornithine cyclodeaminase
G3580_RS03115	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
G3580_RS03140	ENOG4107TSN	permease
G3580_RS03145	ENOG4107R11	Transcriptional regulator
G3580_RS03155	ENOG4107RP9	extracellular solute-binding protein, family 3
G3580_RS03160	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
G3580_RS03170	ENOG4108JJ7	ABC transporter
G3580_RS03180	ENOG4108R5S	membrane
G3580_RS03185	ENOG4105E0F	Histidine kinase
G3580_RS03190	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G3580_RS03205	ENOG4107QPN	acyl-Coa dehydrogenase
G3580_RS03220	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G3580_RS03225	ENOG4105NAU	thioesterase Superfamily protein
G3580_RS03230	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
G3580_RS03240	ENOG4105CHU	acetyl-coa acetyltransferase
G3580_RS03245	ENOG4105BZU	Histidine kinase
G3580_RS03250	ENOG4105BZU	Histidine kinase
G3580_RS03270	ENOG4105I93	response regulator
G3580_RS03280	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS03285	ENOG4107S74	Lysophospholipid transporter LplT
G3580_RS03320	ENOG41085EG	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
G3580_RS03325	ENOG4105KME	endoribonuclease L-psp
G3580_RS03330	ENOG4105CB5	ATP-dependent DNA helicase recG
G3580_RS03335	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
G3580_RS03340	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G3580_RS03350	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
G3580_RS03360	ENOG4105PW4	Sugar fermentation stimulation protein homolog
G3580_RS03370	ENOG4105E4C	Lytic transglycosylase catalytic
G3580_RS03375	ENOG4105D3Q	Sugar transferase
G3580_RS03395	ENOG4105DAY	polysaccharide export protein
G3580_RS03405	ENOG4105D75	Capsular exopolysaccharide family
G3580_RS03480	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G3580_RS03490	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G3580_RS03510	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G3580_RS03520	ENOG4105XQ6	frataxin-like protein
G3580_RS03525	ENOG4108JQC	penicillin-binding protein 1A
G3580_RS03550	ENOG4105E4G	Type IV pilus
G3580_RS03555	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G3580_RS03560	ENOG4105D49	3-dehydroquinate synthase
G3580_RS03565	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G3580_RS03590	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G3580_RS03595	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G3580_RS03610	ENOG4108VYJ	response regulator receiver protein
G3580_RS03615	ENOG4108NVR	Methyl-accepting chemotaxis
G3580_RS03625	ENOG4105CBS	Chea signal transduction histidine kinase
G3580_RS03630	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS03635	ENOG4108V3W	Chemotaxis protein, CheW
G3580_RS03640	ENOG4105BZU	Histidine kinase
G3580_RS03645	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G3580_RS03650	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G3580_RS03655	ENOG4105BZU	Histidine kinase
G3580_RS03660	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G3580_RS03670	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G3580_RS03675	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G3580_RS03680	ENOG4105BZU	Histidine kinase
G3580_RS03685	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G3580_RS03690	ENOG4105BZU	Histidine kinase
G3580_RS03730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS03735	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
G3580_RS03740	ENOG4105EAQ	(twin-arginine translocation) pathway signal
G3580_RS03755	ENOG4108MN8	Membrane
G3580_RS03760	ENOG41063Z6	transcriptional regulator, lysR family
G3580_RS03765	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G3580_RS03775	ENOG4105BZS	acriflavin resistance protein
G3580_RS03835	ENOG4105WQ5	TonB family
G3580_RS03840	ENOG4108UQY	Iron-storage protein
G3580_RS03855	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
G3580_RS03865	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G3580_RS03870	ENOG4108YXG	UPF0502 protein
G3580_RS03875	ENOG4107QP8	phosphohexose isomerase
G3580_RS03880	ENOG4105C01	Dihydroxy-acid dehydratase
G3580_RS03890	ENOG4105CYM	Glutathione S-transferase
G3580_RS03930	ENOG4108USZ	hydrogenase
G3580_RS03935	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
G3580_RS03940	ENOG4105YYZ	Hydrogenase expression formation protein
G3580_RS03950	ENOG4107UY0	rubredoxin
G3580_RS03955	ENOG410631X	Hydrogenase expression formation protein
G3580_RS03965	ENOG41081J6	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
G3580_RS03970	ENOG4107RSS	Hydrogenase accessory protein HypB
G3580_RS04000	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G3580_RS04010	ENOG4105CJ3	phosphate transporter
G3580_RS04015	ENOG4105E3S	small subunit
G3580_RS04035	ENOG4105W2Z	cytochrome C, class I
G3580_RS04045	ENOG4105BZU	Histidine kinase
G3580_RS04050	ENOG4105CUX	Signal transduction histidine kinase
G3580_RS04055	ENOG4105D58	Diguanylate phosphodiesterase
G3580_RS04070	ENOG4108YXA	Membrane
G3580_RS04075	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G3580_RS04080	ENOG4105CZX	twitching motility protein
G3580_RS04085	ENOG4105CZX	twitching motility protein
G3580_RS04090	ENOG4105DFA	alanine racemase domain protein
G3580_RS04095	ENOG4105II7	pyrroline-5-carboxylate reductase
G3580_RS04100	ENOG4108VIA	integral membrane protein
G3580_RS04105	ENOG4105VZ9	UPF0235 protein
G3580_RS04110	ENOG4105CD3	dihydroorotase
G3580_RS04115	ENOG4105CXT	aspartate transcarbamylase
G3580_RS04120	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
G3580_RS04125	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G3580_RS04130	ENOG4108UJU	UPF0301 protein
G3580_RS04135	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G3580_RS04145	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS04155	ENOG4105M3Z	response regulator
G3580_RS04160	ENOG4108UNF	response regulator
G3580_RS04165	ENOG4105VCQ	rubredoxin
G3580_RS04175	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G3580_RS04180	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G3580_RS04195	ENOG4105CJW	magnesium transporter
G3580_RS04200	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G3580_RS04205	ENOG4105E2X	shikimate dehydrogenase
G3580_RS04220	ENOG4105FR1	rard protein
G3580_RS04225	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G3580_RS04230	ENOG4105IPS	esterase
G3580_RS04235	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G3580_RS04295	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G3580_RS04310	ENOG4105CJ1	ABC, transporter
G3580_RS04325	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G3580_RS04330	ENOG4108Z9W	Outer membrane porin
G3580_RS04335	ENOG4105DZG	Dehydrogenase
G3580_RS04365	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS04370	ENOG4106Z86	ATP-nad acox kinase
G3580_RS04375	ENOG4107R0V	Pyruvate dehydrogenase
G3580_RS04380	ENOG4105CPP	Dehydrogenase, E1 component
G3580_RS04385	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
G3580_RS04390	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G3580_RS04395	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G3580_RS04405	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G3580_RS04410	ENOG4107QN2	dihydrolipoyl dehydrogenase
G3580_RS04415	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G3580_RS04430	ENOG4105VEQ	Cold shock protein
G3580_RS04440	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G3580_RS04445	ENOG4107RK0	Sucrose phosphorylase
G3580_RS04450	ENOG4105DWF	phosphomethylpyrimidine kinase
G3580_RS04455	ENOG4108UHE	carbonic anhydrase
G3580_RS04460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G3580_RS04475	ENOG4108R86	Transcriptional regulator
G3580_RS04490	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G3580_RS04495	ENOG4105VFE	sira family
G3580_RS04500	ENOG4105DFG	type I secretion outer membrane protein
G3580_RS04505	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G3580_RS04515	ENOG4105BZ1	(ABC) transporter
G3580_RS04525	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G3580_RS04540	ENOG4105DTD	Dehydrogenase
G3580_RS04545	ENOG4105F0R	Cytidylyltransferase
G3580_RS04550	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G3580_RS04560	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G3580_RS04585	ENOG4105D2T	synthase
G3580_RS04600	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
G3580_RS04605	ENOG4108JQ1	Dehydrogenase
G3580_RS04610	ENOG4105CMR	udp-glucose 4-epimerase
G3580_RS04630	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
G3580_RS04635	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G3580_RS04640	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G3580_RS04645	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G3580_RS04660	ENOG4105CMR	udp-glucose 4-epimerase
G3580_RS04665	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G3580_RS04700	ENOG4105C5E	polysaccharide biosynthesis protein
G3580_RS04705	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G3580_RS04715	ENOG4105D3Q	Sugar transferase
G3580_RS04725	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G3580_RS04735	ENOG4105NNS	Autoinducer synthesis protein
G3580_RS04755	ENOG41080IJ	Diacylglycerol kinase
G3580_RS04775	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G3580_RS04780	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G3580_RS04785	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G3580_RS04790	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G3580_RS04795	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3580_RS04805	ENOG4105DFU	Cell wall formation (By similarity)
G3580_RS04815	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
G3580_RS04820	ENOG41082RQ	UPF0102 protein
G3580_RS04825	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G3580_RS04830	ENOG4105EKE	dihydroorotase
G3580_RS04850	ENOG4108V6E	Cell division protein mraZ
G3580_RS04855	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G3580_RS04865	ENOG4105CJN	penicillin-binding protein
G3580_RS04870	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G3580_RS04875	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G3580_RS04890	ENOG4105CNI	cell division protein FtsW
G3580_RS04895	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G3580_RS04900	ENOG4105DFU	Cell wall formation (By similarity)
G3580_RS04905	ENOG4105CPF	Cell wall formation (By similarity)
G3580_RS04910	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G3580_RS04915	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G3580_RS04920	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G3580_RS04925	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G3580_RS04940	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G3580_RS04950	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G3580_RS04990	ENOG4105NWN	ApaG protein
G3580_RS04995	ENOG4105DJV	ribulose-phosphate 3-epimerase
G3580_RS05000	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G3580_RS05010	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G3580_RS05020	ENOG4105DDQ	anthranilate synthase
G3580_RS05025	ENOG4107QYG	anthranilate phosphoribosyltransferase
G3580_RS05030	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G3580_RS05045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G3580_RS05050	ENOG4105CK2	sodium dicarboxylate symporter
G3580_RS05055	ENOG4105C7I	Dehydrogenase
G3580_RS05065	ENOG4105HUJ	glyoxalase bleomycin resistance protein dioxygenase
G3580_RS05085	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
G3580_RS05090	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G3580_RS05095	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
G3580_RS05105	ENOG4105BZU	Histidine kinase
G3580_RS05110	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G3580_RS05140	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G3580_RS05150	ENOG4105CT4	transporter
G3580_RS05160	ENOG4108IXY	short-chain dehydrogenase reductase
G3580_RS05170	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G3580_RS05175	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G3580_RS05180	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
G3580_RS05190	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
G3580_RS05200	ENOG4108R6F	Surfeit locus 1 family protein
G3580_RS05215	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G3580_RS05220	ENOG4108ZX6	Electron transport protein SCO1 SenC
G3580_RS05230	ENOG4108JJA	ABC, transporter
G3580_RS05240	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS05265	ENOG4105DFG	type I secretion outer membrane protein
G3580_RS05270	ENOG4105C9Q	fumarate hydratase class II
G3580_RS05275	ENOG4105CFP	Peptidase U32
G3580_RS05280	ENOG41062QD	Membrane
G3580_RS05285	ENOG4107QN1	sodium solute
G3580_RS05295	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G3580_RS05300	ENOG4105CBC	glutamate synthase
G3580_RS05310	ENOG4105EYU	Glutamine amido-transferase
G3580_RS05315	ENOG4105CFQ	glutamine synthetase
G3580_RS05325	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G3580_RS05350	ENOG4105BZU	Histidine kinase
G3580_RS05365	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G3580_RS05370	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G3580_RS05375	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G3580_RS05380	ENOG4105DHQ	Histidine kinase
G3580_RS05390	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G3580_RS05395	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G3580_RS05400	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G3580_RS05435	ENOG4105D9P	serine threonine protein kinase
G3580_RS05440	ENOG4105CH7	arginosuccinase
G3580_RS05445	ENOG4108HRK	Histidine kinase
G3580_RS05450	ENOG4108NEV	two component transcriptional regulator, LytTR family
G3580_RS05460	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
G3580_RS05470	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G3580_RS05475	ENOG41076E6	Uroporphyrinogen-III Synthase
G3580_RS05485	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G3580_RS05495	ENOG4105C12	Phosphoribosylglycinamide synthetase
G3580_RS05505	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G3580_RS05510	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G3580_RS05515	ENOG4105D0A	hydroxylase
G3580_RS05520	ENOG4107RAQ	aminopeptidase
G3580_RS05525	ENOG4108S0S	Nucleotidyl transferase
G3580_RS05530	ENOG4105EHM	Aminoglycoside phosphotransferase
G3580_RS05535	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G3580_RS05540	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G3580_RS05545	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G3580_RS05550	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G3580_RS05560	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS05580	ENOG4105BZU	Histidine kinase
G3580_RS05585	ENOG4105DGW	oligopeptidase A
G3580_RS05595	ENOG4105C8V	SAICAR synthetase
G3580_RS05605	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
G3580_RS05625	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G3580_RS05630	ENOG4105CA9	Pyruvate kinase
G3580_RS05640	ENOG4105BZA	Phosphoglycerate kinase
G3580_RS05645	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G3580_RS05650	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G3580_RS05655	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G3580_RS05665	ENOG4105ECY	inositol monophosphatase
G3580_RS05670	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G3580_RS05675	ENOG4105CSR	polyphosphate kinase 2
G3580_RS05680	ENOG4108EKC	n-acetylglutamate synthase
G3580_RS05685	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
G3580_RS05690	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G3580_RS05695	ENOG4105E66	phosphoriboisomerase A
G3580_RS05705	ENOG4105D64	Mechanosensitive ion channel
G3580_RS05710	ENOG41081QV	Universal stress protein
G3580_RS05715	ENOG4107QN1	sodium solute
G3580_RS05730	ENOG41067MG	lrgb family
G3580_RS05800	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G3580_RS05815	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G3580_RS05845	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G3580_RS05860	ENOG4105FQT	
G3580_RS05865	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G3580_RS05875	ENOG4108YY7	Invasion gene expression up-regulator SirB
G3580_RS05885	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G3580_RS05890	ENOG4105D4P	Coproporphyrinogen iii oxidase
G3580_RS05910	ENOG4105C59	p-type ATPase
G3580_RS05920	ENOG4105BZU	Histidine kinase
G3580_RS05925	ENOG4105F0N	pyrophosphate phospho-hydrolase
G3580_RS05935	ENOG4105C4K	Nad synthetase
G3580_RS05940	ENOG4108YZA	Nitrogen regulatory protein pii
G3580_RS05945	ENOG4108DG9	Smr protein MutS2
G3580_RS05950	ENOG4105C3M	thioredoxin reductase
G3580_RS05955	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
G3580_RS05960	ENOG4105CNU	cell division protein FtsK
G3580_RS05965	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
G3580_RS05970	ENOG4105D1H	recombination factor protein RarA
G3580_RS05980	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G3580_RS05985	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
G3580_RS06000	ENOG4105BZU	Histidine kinase
G3580_RS06005	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS06015	ENOG4105CBP	Major Facilitator
G3580_RS06020	ENOG4105BZU	Histidine kinase
G3580_RS06025	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G3580_RS06030	ENOG4105VS8	Flagellar biosynthetic protein fliq
G3580_RS06035	ENOG4105CN7	Flagellar biosynthetic protein FliP
G3580_RS06040	ENOG4105K0P	flagellar biosynthesis protein
G3580_RS06055	ENOG4105E18	UPF0276 protein
G3580_RS06070	ENOG4105EGS	Mechanosensitive ion channel
G3580_RS06100	ENOG4105DD5	Flagellar motor switch protein
G3580_RS06105	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G3580_RS06120	ENOG4105GSA	Flagellar export protein flij
G3580_RS06125	ENOG4108JIR	Flagellum-specific ATP synthase
G3580_RS06135	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G3580_RS06140	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G3580_RS06145	ENOG4105BZU	Histidine kinase
G3580_RS06155	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
G3580_RS06170	ENOG4105CH5	extracellular solute-binding protein, family 7
G3580_RS06175	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G3580_RS06180	ENOG4105N42	UPF0307 protein
G3580_RS06185	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G3580_RS06190	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
G3580_RS06195	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
G3580_RS06200	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G3580_RS06215	ENOG4105D2N	Aldolase
G3580_RS06220	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G3580_RS06225	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
G3580_RS06230	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G3580_RS06235	ENOG4106F1P	AAA ATPase, central domain protein
G3580_RS06240	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
G3580_RS06245	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
G3580_RS06250	ENOG4105DUM	transcriptional regulator, lysR family
G3580_RS06265	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G3580_RS06280	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G3580_RS06285	ENOG4108M8S	permease YjgP YjgQ family protein
G3580_RS06295	ENOG4105DJ9	glucan biosynthesis protein
G3580_RS06310	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G3580_RS06315	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G3580_RS06320	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G3580_RS06325	ENOG4105K5M	30s ribosomal protein S16
G3580_RS06330	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
G3580_RS06340	ENOG4107S2Z	UPF0761 membrane protein
G3580_RS06345	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G3580_RS06355	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G3580_RS06360	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G3580_RS06365	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
G3580_RS06370	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G3580_RS06375	ENOG4108ZP8	Acetolactate synthase small subunit
G3580_RS06380	ENOG4105C7K	acetolactate synthase
G3580_RS06405	ENOG4107T9Q	phosphonate abc transporter
G3580_RS06440	ENOG4108NVR	Methyl-accepting chemotaxis
G3580_RS06450	ENOG4105BZU	Histidine kinase
G3580_RS06455	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
G3580_RS06460	ENOG4105D00	flagellar biosynthetic protein flhB
G3580_RS06475	ENOG4105MQ3	flagellar protein FliS
G3580_RS06480	ENOG4105DTS	flagellar hook-associated
G3580_RS06490	ENOG4105I03	Flagellin
G3580_RS06505	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G3580_RS06530	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G3580_RS06535	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G3580_RS06540	ENOG4105FAW	cDP-glucose 4,6-dehydratase
G3580_RS06545	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
G3580_RS06560	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS06595	ENOG4105MP0	transposase
G3580_RS06605	ENOG4108RPX	mosc domain containing protein
G3580_RS06630	ENOG4105ETT	transcriptional Regulator, LysR family
G3580_RS06635	ENOG4105EMU	Dehydrogenase
G3580_RS06660	ENOG4107QN1	sodium solute
G3580_RS06685	ENOG4105EA8	2-Nitropropane dioxygenase
G3580_RS06695	ENOG4107QN1	sodium solute
G3580_RS06700	ENOG41062QD	Membrane
G3580_RS06710	ENOG4105C26	Dehydrogenase
G3580_RS06720	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
G3580_RS06725	ENOG41090U3	tautomerase
G3580_RS06730	ENOG4105BZJ	Electron transfer flavoprotein
G3580_RS06735	ENOG4105C10	Electron transfer flavoprotein
G3580_RS06755	ENOG4105BZU	Histidine kinase
G3580_RS06760	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS06770	ENOG4105C28	cystathionine
G3580_RS06775	ENOG4105BZ1	(ABC) transporter
G3580_RS06800	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G3580_RS06805	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G3580_RS06810	ENOG4105UYK	outer membrane protein a
G3580_RS06815	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G3580_RS06820	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G3580_RS06845	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G3580_RS06850	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G3580_RS06855	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G3580_RS06865	ENOG4105CFV	Tetratricopeptide repeat protein
G3580_RS06870	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G3580_RS06875	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G3580_RS06880	ENOG4105C6T	cysteine synthase
G3580_RS06920	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G3580_RS06925	ENOG4105VJV	50s ribosomal protein L35
G3580_RS06930	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G3580_RS06935	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G3580_RS06940	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G3580_RS06945	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G3580_RS06980	ENOG4105CAY	ferredoxin--nadp reductase
G3580_RS07000	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
G3580_RS07005	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G3580_RS07010	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
G3580_RS07015	ENOG4105CQM	Urea amidohydrolase subunit alpha
G3580_RS07020	ENOG4105KI2	Urea amidohydrolase subunit beta
G3580_RS07025	ENOG4108YZ9	Urea amidohydrolase subunit gamma
G3580_RS07030	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G3580_RS07035	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G3580_RS07045	ENOG4105WQ3	Rna-binding protein
G3580_RS07050	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G3580_RS07060	ENOG4105CPD	ethanolamine ammonia-lyase
G3580_RS07065	ENOG4107FQ9	ethanolamine ammonia-lyase
G3580_RS07070	ENOG4108IV0	ABC, transporter
G3580_RS07075	ENOG4105C0Z	ABC transporter
G3580_RS07080	ENOG4105CNN	ABC, transporter
G3580_RS07085	ENOG4105C32	Amino acid ABC transporter (Permease)
G3580_RS07090	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
G3580_RS07095	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS07130	ENOG4105C08	Histidine kinase
G3580_RS07135	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
G3580_RS07140	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G3580_RS07145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS07150	ENOG4105BZU	Histidine kinase
G3580_RS07155	ENOG4105PWN	phosphate abc transporter
G3580_RS07160	ENOG4105C8U	phosphate abc transporter
G3580_RS07170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS07225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G3580_RS07235	ENOG4105CS6	Rhs element vgr protein
G3580_RS07260	ENOG4105BZU	Histidine kinase
G3580_RS07265	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G3580_RS07275	ENOG4105DPX	Hydrogenase, large subunit
G3580_RS07285	ENOG4105BZU	Histidine kinase
G3580_RS07300	ENOG4105DGU	Histone deacetylase
G3580_RS07305	ENOG4107QS8	(LipO)protein
G3580_RS07310	ENOG4105EUJ	GTP cyclohydrolase i
G3580_RS07340	ENOG4105EEQ	Na H antiporter
G3580_RS07350	ENOG4105CHB	tonB-dependent Receptor
G3580_RS07365	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
G3580_RS07370	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
G3580_RS07395	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS07400	ENOG4105BZU	Histidine kinase
G3580_RS07420	ENOG4105DZG	Dehydrogenase
G3580_RS07440	ENOG4105BZU	Histidine kinase
G3580_RS07455	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS07465	ENOG4105C26	Dehydrogenase
G3580_RS07480	ENOG4105DZG	Dehydrogenase
G3580_RS07485	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS07520	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G3580_RS07525	ENOG4105C9X	ppx gppa phosphatase
G3580_RS07530	ENOG4105CY3	ABC transporter, permease
G3580_RS07535	ENOG4105DHJ	ABC, transporter
G3580_RS07550	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS07560	ENOG4105F8V	Hydrolase, tatD family
G3580_RS07570	ENOG4105BZJ	Electron transfer flavoprotein
G3580_RS07575	ENOG4105C10	Electron transfer flavoprotein
G3580_RS07585	ENOG4105CSU	acyl-Coa dehydrogenase
G3580_RS07590	ENOG4107TF3	peptidylprolyl cis-trans isomerase
G3580_RS07600	ENOG4105K9H	YciI-like protein
G3580_RS07605	ENOG4107835	probably involved in intracellular septation (By similarity)
G3580_RS07620	ENOG4105E0F	Histidine kinase
G3580_RS07635	ENOG41072GX	Peptidase M22 Glycoprotease
G3580_RS07640	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
G3580_RS07645	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G3580_RS07665	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
G3580_RS07675	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G3580_RS07695	ENOG4105ECQ	AraC Family Transcriptional Regulator
G3580_RS07705	ENOG4105DP0	ferredoxin-NADP reductase
G3580_RS07720	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
G3580_RS07725	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G3580_RS07740	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G3580_RS07755	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
G3580_RS07760	ENOG4105BZU	Histidine kinase
G3580_RS07765	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G3580_RS07775	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS07780	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
G3580_RS07785	ENOG4105CH5	extracellular solute-binding protein, family 7
G3580_RS07800	ENOG4105CSU	acyl-Coa dehydrogenase
G3580_RS07805	ENOG4105CC0	LysR family Transcriptional regulator
G3580_RS07810	ENOG4105EUB	pirin domain protein
G3580_RS07815	ENOG4105CHJ	isochorismatase hydrolase
G3580_RS07825	ENOG4105D5U	fad dependent oxidoreductase
G3580_RS07840	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS07855	ENOG4105C94	Transporter
G3580_RS07865	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
G3580_RS07885	ENOG4105CTD	carboxy-peptidase
G3580_RS07890	ENOG4105CA0	peroxidase
G3580_RS07920	ENOG4105C4R	Atp-dependent dna helicase
G3580_RS07960	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3580_RS07965	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G3580_RS07970	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G3580_RS07980	ENOG4105DB7	PHP domain protein
G3580_RS07985	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G3580_RS07990	ENOG4108Z4T	Peptidase M50
G3580_RS07995	ENOG4105C31	Tryptophanyl-tRNA synthetase
G3580_RS08000	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G3580_RS08005	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G3580_RS08010	ENOG4105FE9	pseudouridine synthase
G3580_RS08015	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G3580_RS08020	ENOG4105CHV	Transcription elongation factor NusA
G3580_RS08025	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G3580_RS08030	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G3580_RS08035	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G3580_RS08040	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G3580_RS08045	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G3580_RS08155	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
G3580_RS08265	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G3580_RS08270	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G3580_RS08315	ENOG41061ZR	Transcriptional regulator
G3580_RS08340	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G3580_RS08345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G3580_RS08355	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS08360	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G3580_RS08370	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
G3580_RS08375	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G3580_RS08380	ENOG4105M00	molybdopterin converting factor, subunit 1
G3580_RS08385	ENOG4108ZAF	Molybdopterin
G3580_RS08395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G3580_RS08430	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
G3580_RS08450	ENOG4105C58	cytochrome c oxidase accessory protein ccog
G3580_RS08465	ENOG4105E6M	Sulphatase-modifying factor protein
G3580_RS08470	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G3580_RS08480	ENOG4108V1U	phospholipid-binding protein
G3580_RS08500	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
G3580_RS08505	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS08510	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G3580_RS08535	ENOG4105BZU	Histidine kinase
G3580_RS08540	ENOG4105CYM	Glutathione S-transferase
G3580_RS08545	ENOG4107U4J	modification
G3580_RS08555	ENOG4105VEQ	Cold shock protein
G3580_RS08560	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
G3580_RS08565	ENOG4105EEI	dihydropteroate synthase
G3580_RS08570	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G3580_RS08575	ENOG4105CP7	Triose-phosphate isomerase
G3580_RS08580	ENOG4107EJC	Preprotein translocase subunit SecG
G3580_RS08590	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G3580_RS08595	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS08600	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G3580_RS08605	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS08610	ENOG4105GKE	subunit e
G3580_RS08615	ENOG4107QIZ	NADH dehydrogenase
G3580_RS08620	ENOG4108IEH	NADH dehydrogenase subunit g
G3580_RS08625	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G3580_RS08630	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS08635	ENOG4105DF2	NADH dehydrogenase subunit j
G3580_RS08640	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS08650	ENOG4105C8S	subunit m
G3580_RS08655	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS08660	ENOG4108YZ4	nudix hydrolase
G3580_RS08665	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G3580_RS08670	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS08675	ENOG4105BZU	Histidine kinase
G3580_RS08710	ENOG4105PGM	cation diffusion facilitator family transporter
G3580_RS08740	ENOG4108RRZ	Transcription elongation factor GreB
G3580_RS08745	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
G3580_RS08750	ENOG4105CMQ	Chloride channel
G3580_RS08755	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G3580_RS08765	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G3580_RS08770	ENOG4105FDP	GntR family transcriptional regulator
G3580_RS08790	ENOG4105E33	succinate dehydrogenase
G3580_RS08795	ENOG410681N	tpr repeat protein
G3580_RS08800	ENOG4105BZN	citrate synthase
G3580_RS08805	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G3580_RS08810	ENOG4105C7S	Dehydrogenase
G3580_RS08815	ENOG4107QN2	dihydrolipoyl dehydrogenase
G3580_RS08820	ENOG4105D6Z	AFG1 family ATPase
G3580_RS08830	ENOG4105DVT	helicase
G3580_RS08835	ENOG4105CH2	amidohydrolase
G3580_RS08840	ENOG4105CV6	ABC transporter, permease
G3580_RS08850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G3580_RS08865	ENOG4105CGF	Aromatic amino acid aminotransferase
G3580_RS08870	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G3580_RS08880	ENOG4105C03	ribonuclease
G3580_RS08885	ENOG4105EI2	Pseudouridine synthase
G3580_RS08900	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G3580_RS08905	ENOG4108UHJ	MAF-like protein
G3580_RS08910	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G3580_RS08915	ENOG4105VGS	50s ribosomal protein l32
G3580_RS08920	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
G3580_RS08925	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G3580_RS08930	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G3580_RS08935	ENOG4105CHR	reductase
G3580_RS08940	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G3580_RS08945	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G3580_RS08955	ENOG4108IYU	L-aspartate oxidase
G3580_RS08960	ENOG4105EMN	RNA polymerase sigma factor
G3580_RS08980	ENOG4105C0H	protease
G3580_RS08990	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G3580_RS08995	ENOG4105C3F	Signal peptidase i
G3580_RS09005	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G3580_RS09010	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G3580_RS09015	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G3580_RS09020	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G3580_RS09025	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G3580_RS09030	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
G3580_RS09040	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G3580_RS09075	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
G3580_RS09080	ENOG4107QMS	site-determining protein
G3580_RS09085	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
G3580_RS09090	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G3580_RS09095	ENOG4105KUZ	arsenate reductase
G3580_RS09100	ENOG4105BZM	domain protein
G3580_RS09115	ENOG4108R3E	Dna-3-methyladenine glycosylase i
G3580_RS09120	ENOG4105CD5	CoA-binding domain protein
G3580_RS09125	ENOG4105E0F	Histidine kinase
G3580_RS09130	ENOG4105C26	Dehydrogenase
G3580_RS09140	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
G3580_RS09145	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
G3580_RS09155	ENOG4108UJV	acyl-CoA thioesterase i
G3580_RS09160	ENOG4108I0Y	(ABC) transporter
G3580_RS09165	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
G3580_RS09170	ENOG4105FE1	phytoene synthase
G3580_RS09175	ENOG4105FE1	phytoene synthase
G3580_RS09190	ENOG4105ED1	spovr family
G3580_RS09195	ENOG4106AKX	UPF0229 protein
G3580_RS09200	ENOG4105CYN	Serine protein kinase
G3580_RS09205	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G3580_RS09210	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G3580_RS09215	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G3580_RS09220	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G3580_RS09240	ENOG4107TF3	peptidylprolyl cis-trans isomerase
G3580_RS09245	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G3580_RS09250	ENOG4105DEF	Extracellular solute-binding protein, family 5
G3580_RS09255	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G3580_RS09260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G3580_RS09285	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
G3580_RS09295	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
G3580_RS09300	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G3580_RS09315	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G3580_RS09325	ENOG4108IPJ	Membrane
G3580_RS09330	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G3580_RS09340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G3580_RS09365	ENOG4108F3G	Type I restriction-modification system, R subunit
G3580_RS09380	ENOG4107QTH	restriction modification system DNA specificity domain
G3580_RS09415	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G3580_RS09425	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G3580_RS09435	ENOG4105CRK	lysyL-tRNA synthetase
G3580_RS09440	ENOG4105BZU	Histidine kinase
G3580_RS09445	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G3580_RS09465	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G3580_RS09475	ENOG4105F4R	Transcriptional regulator mode
G3580_RS09480	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G3580_RS09495	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G3580_RS09500	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS09510	ENOG4108EC8	DNA internalization-related competence protein ComEC
G3580_RS09530	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G3580_RS09540	ENOG4105DR5	peptidase
G3580_RS09560	ENOG4107QX8	SPFH domain, Band 7 family protein
G3580_RS09565	ENOG4107G9V	glycosyl transferase, family 39
G3580_RS09575	ENOG4105CKK	Glycosyl transferase, family 2
G3580_RS09585	ENOG4106CKV	Pap2 superfamily protein
G3580_RS09590	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
G3580_RS09600	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G3580_RS09610	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G3580_RS09620	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G3580_RS09625	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G3580_RS09630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G3580_RS09635	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G3580_RS09645	ENOG4105K4H	Nlp p60 protein
G3580_RS09650	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G3580_RS09670	ENOG4108Z0R	Transferase
G3580_RS09685	ENOG4108UKI	Enoyl-CoA hydratase
G3580_RS09705	ENOG4105CBX	hi0933 family
G3580_RS09715	ENOG4105KZX	Pterin carbinolamine dehydratase
G3580_RS09740	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
G3580_RS09760	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
G3580_RS09775	ENOG4105EQ2	LysR family Transcriptional regulator
G3580_RS09780	ENOG4105BZU	Histidine kinase
G3580_RS09785	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G3580_RS09810	ENOG4105GR3	Histidine kinase
G3580_RS09815	ENOG4105E3B	Multicopper oxidase
G3580_RS09865	ENOG4107QX9	Thiol disulfide interChange protein
G3580_RS09870	ENOG4107QIV	Cytochrome c biogenesis protein
G3580_RS09885	ENOG4105C7F	AcnD-accessory protein PrpF
G3580_RS09890	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
G3580_RS09900	ENOG41079YP	Citrate utilization protein b
G3580_RS09910	ENOG4106P55	Transcriptional regulator
G3580_RS09920	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
G3580_RS09925	ENOG4105CI0	Citrate lyase
G3580_RS09930	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G3580_RS09935	ENOG4108M9J	MaoC like domain protein
G3580_RS09940	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS09945	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
G3580_RS09950	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G3580_RS09955	ENOG4105C7F	AcnD-accessory protein PrpF
G3580_RS09960	ENOG4105F04	LysR family Transcriptional regulator
G3580_RS09970	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G3580_RS09975	ENOG4108JB9	formate dehydrogenase
G3580_RS09990	ENOG4105EGI	Transcriptional regulator
G3580_RS10000	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS10010	ENOG4105F8V	Hydrolase, tatD family
G3580_RS10020	ENOG4107QRG	dna polymerase iii
G3580_RS10025	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G3580_RS10030	ENOG4105HHA	aminodeoxychorismate lyase
G3580_RS10035	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G3580_RS10060	ENOG4108Z6B	deaminase
G3580_RS10065	ENOG4105BZU	Histidine kinase
G3580_RS10085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G3580_RS10090	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G3580_RS10100	ENOG4105VDB	UPF0125 protein
G3580_RS10105	ENOG4108Z1B	Cyclase dehydrase
G3580_RS10110	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G3580_RS10125	ENOG4105H1G	trap transporter solute receptor taxi family
G3580_RS10135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G3580_RS10140	ENOG4105CW7	secretion protein, HlyD family
G3580_RS10145	ENOG4108ZT1	Transcriptional regulator
G3580_RS10160	ENOG4105C0B	DNA polymerase III (alpha subunit)
G3580_RS10180	ENOG4108JA2	transcriptioN-repair coupling factor
G3580_RS10185	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G3580_RS10190	ENOG4105EAC	phosphoserine phosphatase
G3580_RS10205	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G3580_RS10210	ENOG4105DS1	cytochrome b561
G3580_RS10220	ENOG4108YYC	ycei family
G3580_RS10225	ENOG4105CHF	Glutathione S-transferase
G3580_RS10250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS10260	ENOG4107WP9	Histidine kinase
G3580_RS10285	ENOG4105BZU	Histidine kinase
G3580_RS10300	ENOG4108DBC	nitroreductase
G3580_RS10305	ENOG4108RH0	Crea protein
G3580_RS10310	ENOG4107QHF	type ii secretion system protein e
G3580_RS10325	ENOG4108YHQ	outer membrane protein B
G3580_RS10330	ENOG4105DR4	Methyltransferase
G3580_RS10360	ENOG4105D1Q	UPF0246 protein
G3580_RS10370	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G3580_RS10375	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G3580_RS10380	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G3580_RS10385	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G3580_RS10390	ENOG4105CHH	sulfate transporter
G3580_RS10405	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G3580_RS10410	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G3580_RS10415	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G3580_RS10420	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G3580_RS10425	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G3580_RS10435	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3580_RS10440	ENOG4105DZP	Membrane-associated zinc metalloprotease
G3580_RS10445	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G3580_RS10450	ENOG4105KNE	Phosphatidate cytidylyltransferase
G3580_RS10455	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G3580_RS10460	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G3580_RS10465	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G3580_RS10470	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G3580_RS10475	ENOG4105CE9	30S ribosomal protein S2
G3580_RS10480	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G3580_RS10485	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G3580_RS10490	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
G3580_RS10495	ENOG4105CI3	gtp-binding protein typa
G3580_RS10500	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G3580_RS10505	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G3580_RS10515	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G3580_RS10525	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
G3580_RS10530	ENOG4105CZX	twitching motility protein
G3580_RS10535	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G3580_RS10540	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G3580_RS10545	ENOG41069D7	Methyl-accepting chemotaxis
G3580_RS10555	ENOG4105WVQ	Fe-S assembly protein IscX
G3580_RS10560	ENOG4108ZIT	Ferredoxin, 2FE-2S
G3580_RS10565	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
G3580_RS10570	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
G3580_RS10575	ENOG4108Z4V	iron-sulfur cluster assembly
G3580_RS10580	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G3580_RS10585	ENOG4105C3J	Cysteine desulfurase
G3580_RS10590	ENOG4107QI6	Cysteine desulfurase
G3580_RS10600	ENOG4105D7W	serine acetyltransferase
G3580_RS10610	ENOG4105ECY	inositol monophosphatase
G3580_RS10615	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G3580_RS10620	ENOG4105IH7	synthase
G3580_RS10625	ENOG4107RZZ	dna polymerase iii epsilon subunit
G3580_RS10630	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G3580_RS10635	ENOG4105D1A	Methyltransferase
G3580_RS10640	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G3580_RS10650	ENOG4105E9H	Lytic Murein transglycosylase
G3580_RS10655	ENOG4108JQ6	ABC transporter
G3580_RS10660	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G3580_RS10670	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G3580_RS10700	ENOG4105CQB	FAD linked oxidase domain protein
G3580_RS10705	ENOG4105D78	K07001 NTE family protein
G3580_RS10710	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G3580_RS10715	ENOG4108NVM	synthesis repressor PhaR
G3580_RS10725	ENOG4105CHR	reductase
G3580_RS10730	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G3580_RS10740	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G3580_RS10745	ENOG4105C34	Pseudouridine synthase
G3580_RS10760	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
G3580_RS10780	ENOG4105CFH	Aspartokinase
G3580_RS10815	ENOG4105NPQ	Pfam:DUF403
G3580_RS10850	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G3580_RS10855	ENOG4105EZE	Cupin 4 family protein
G3580_RS10870	ENOG4105Q2H	domain protein
G3580_RS10875	ENOG4105GJM	(LipO)protein
G3580_RS10880	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G3580_RS10885	ENOG4105DGU	Histone deacetylase
G3580_RS10890	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G3580_RS10900	ENOG4105F8C	transglutaminase domain-containing protein
G3580_RS10910	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G3580_RS10915	ENOG4108K5P	(LipO)protein
G3580_RS10920	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G3580_RS10925	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G3580_RS10965	ENOG4105UYK	outer membrane protein a
G3580_RS10970	ENOG4105CBC	glutamate synthase
G3580_RS10975	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G3580_RS11000	ENOG4105CHM	Aminotransferase
G3580_RS11010	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3580_RS11015	ENOG4108IAB	Phoh family
G3580_RS11035	ENOG4105K4H	Nlp p60 protein
G3580_RS11050	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
G3580_RS11055	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS11060	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G3580_RS11065	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G3580_RS11070	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G3580_RS11075	ENOG4105DGN	Electron transport complex
G3580_RS11080	ENOG4108R3D	Electron transport complex
G3580_RS11085	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
G3580_RS11095	ENOG4108UQQ	Electron transport complex
G3580_RS11105	ENOG4105CSM	endonuclease III
G3580_RS11115	ENOG4106RE7	Cytochrome
G3580_RS11120	ENOG4105N7H	Cytochrome
G3580_RS11125	ENOG4108JJA	ABC, transporter
G3580_RS11135	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
G3580_RS11155	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G3580_RS11185	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G3580_RS11190	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G3580_RS11205	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G3580_RS11210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G3580_RS11215	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G3580_RS11220	ENOG4105BZU	Histidine kinase
G3580_RS11225	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G3580_RS11230	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G3580_RS11235	ENOG41090R7	Ferric uptake
G3580_RS11245	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G3580_RS11250	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G3580_RS11255	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G3580_RS11260	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G3580_RS11280	ENOG4105D9P	serine threonine protein kinase
G3580_RS11285	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3580_RS11290	ENOG4105CFG	Acts as a chaperone (By similarity)
G3580_RS11295	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G3580_RS11310	ENOG4105C8N	cysteinyl-tRNA synthetase
G3580_RS11325	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
G3580_RS11330	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
G3580_RS11335	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
G3580_RS11340	ENOG4105C28	cystathionine
G3580_RS11345	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G3580_RS11360	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G3580_RS11365	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G3580_RS11370	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G3580_RS11375	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G3580_RS11380	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G3580_RS11385	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G3580_RS11390	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
G3580_RS11400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G3580_RS11405	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G3580_RS11410	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G3580_RS11415	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G3580_RS11425	ENOG4105D8G	Major Facilitator superfamily
G3580_RS11435	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G3580_RS11440	ENOG4105M71	acetolactate synthase 1 regulatory subunit
G3580_RS11445	ENOG4105C7K	acetolactate synthase
G3580_RS11450	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS11460	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
G3580_RS11465	ENOG4107RMM	double-strand break repair protein Addb
G3580_RS11470	ENOG4108Z4U	Ferredoxin
G3580_RS11475	ENOG4105K63	Thioredoxin
G3580_RS11480	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G3580_RS11490	ENOG4108NSC	Pfam:DUF88
G3580_RS11500	ENOG4106NZI	LysR family Transcriptional regulator
G3580_RS11505	ENOG4105D94	Major Facilitator Superfamily
G3580_RS11515	ENOG4107QM5	aconitate hydratase
G3580_RS11545	ENOG4105PI0	Ferredoxin
G3580_RS11560	ENOG4106RHG	Yeca family
G3580_RS11580	ENOG4105VFB	Binds the 23S rRNA (By similarity)
G3580_RS11590	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G3580_RS11595	ENOG4105D0M	Protease HtpX homolog
G3580_RS11605	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G3580_RS11610	ENOG4105CHU	acetyl-coa acetyltransferase
G3580_RS11615	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G3580_RS11635	ENOG4108VPT	UPF0234 protein
G3580_RS11640	ENOG4105NBK	UPF0345 protein
G3580_RS11650	ENOG4105CDH	Citrulline--aspartate ligase
G3580_RS11655	ENOG4105DBV	ornithine carbamoyltransferase
G3580_RS11660	ENOG4105C8Y	Acetylornithine aminotransferase
G3580_RS11670	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
G3580_RS11675	ENOG4105CJR	Integral membrane protein (MviN
G3580_RS11680	ENOG4108V1U	phospholipid-binding protein
G3580_RS11685	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G3580_RS11695	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G3580_RS11700	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G3580_RS11705	ENOG4105W49	UPF0434 protein
G3580_RS11710	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G3580_RS11715	ENOG4109015	Biopolymer transport protein exbD tolR
G3580_RS11725	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G3580_RS11730	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G3580_RS11735	ENOG4108WQI	RNA Polymerase
G3580_RS11745	ENOG4105DR9	pseudouridine synthase
G3580_RS11780	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G3580_RS11790	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G3580_RS11795	ENOG4107QN2	dihydrolipoyl dehydrogenase
G3580_RS11825	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G3580_RS11840	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G3580_RS11845	ENOG4108VYJ	response regulator receiver protein
G3580_RS11850	ENOG4107R88	Chemotaxis protein (CheV)
G3580_RS11860	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS11870	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G3580_RS11875	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G3580_RS11880	ENOG4105BZU	Histidine kinase
G3580_RS11885	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS11890	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS11895	ENOG4108V3W	Chemotaxis protein, CheW
G3580_RS11900	ENOG4105CBS	Chea signal transduction histidine kinase
G3580_RS11910	ENOG4105C8Q	Methyl-accepting chemotaxis
G3580_RS11915	ENOG4105ER2	Ompa motb domain protein
G3580_RS11920	ENOG4107RD7	Flagellar Motor Protein, MotA
G3580_RS11925	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
G3580_RS11935	ENOG4105BZU	Histidine kinase
G3580_RS11955	ENOG4105EEQ	Na H antiporter
G3580_RS11960	ENOG4108R99	pseudouridine synthase
G3580_RS11985	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G3580_RS11995	ENOG4105DQR	SNARE associated Golgi
G3580_RS12000	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G3580_RS12010	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G3580_RS12030	ENOG4105DJ9	glucan biosynthesis protein
G3580_RS12040	ENOG4105BZU	Histidine kinase
G3580_RS12050	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
G3580_RS12070	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G3580_RS12075	ENOG4105DHQ	Histidine kinase
G3580_RS12090	ENOG4105E3A	(ABC) transporter
G3580_RS12095	ENOG4105DA5	(ABC) transporter
G3580_RS12110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS12120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G3580_RS12125	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G3580_RS12145	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G3580_RS12150	ENOG4105ERG	peptidase m48, ste24p
G3580_RS12155	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G3580_RS12160	ENOG4105I7R	Adenylate cyclase
G3580_RS12180	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G3580_RS12195	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G3580_RS12210	ENOG4105DNZ	Alpha Beta Hydrolase
G3580_RS12215	ENOG4107QKV	phosphomannomutase
G3580_RS12220	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G3580_RS12235	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G3580_RS12240	ENOG4105DND	Transcriptional regulator
G3580_RS12250	ENOG4105EVH	UPF0753 protein
G3580_RS12260	ENOG4105E09	nadh pyrophosphatase
G3580_RS12265	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G3580_RS12275	ENOG4108WBT	adenosyltransferase
G3580_RS12295	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
G3580_RS12310	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS12325	ENOG4108KEZ	Dehydrogenase
G3580_RS12355	ENOG4107S2E	monooxygenase
G3580_RS12375	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G3580_RS12380	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G3580_RS12385	ENOG4105CC0	LysR family Transcriptional regulator
G3580_RS12405	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
G3580_RS12420	ENOG4105DTJ	flagellar hook-associated protein
G3580_RS12425	ENOG4105E1Q	flagellar hook-associated protein
G3580_RS12430	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G3580_RS12440	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G3580_RS12445	ENOG4105CGA	flagellar basal-body rod protein FlgG
G3580_RS12450	ENOG4108KPB	Flagellar basal-body rod protein FlgF
G3580_RS12455	ENOG4105BZE	flagellar hook protein, FlgE
G3580_RS12460	ENOG4105W00	Flagellar hook capping protein
G3580_RS12465	ENOG4108ZC9	flagellar basal-body rod protein flgc
G3580_RS12470	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G3580_RS12490	ENOG4105EST	Metal Dependent Phosphohydrolase
G3580_RS12495	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G3580_RS12500	ENOG4105XMH	SpoVT AbrB domain protein
G3580_RS12505	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
G3580_RS12510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G3580_RS12520	ENOG4105W3S	hemerythrin-like, metal-binding protein
G3580_RS12525	ENOG4106VK6	Flagellar motor protein
G3580_RS12530	ENOG4105E14	MotA TolQ exbB proton channel
G3580_RS12535	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G3580_RS12550	ENOG4105D7B	Flagellar biosynthesis protein flha
G3580_RS12555	ENOG4105D00	flagellar biosynthetic protein flhB
G3580_RS12590	ENOG4105CDU	Replicative dna helicase
G3580_RS12595	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G3580_RS12600	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G3580_RS12610	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G3580_RS12620	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G3580_RS12630	ENOG4105BZU	Histidine kinase
G3580_RS12640	ENOG4105BZU	Histidine kinase
G3580_RS12650	ENOG4107JPU	
G3580_RS12660	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS12670	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G3580_RS12680	ENOG4105GAK	amidohydrolase 2
G3580_RS12695	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
G3580_RS12715	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G3580_RS12720	ENOG4105W3S	hemerythrin-like, metal-binding protein
G3580_RS12760	ENOG4105QVC	MOSC domain-containing protein
G3580_RS12815	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G3580_RS12835	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
G3580_RS12845	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G3580_RS12860	ENOG4107TE5	Lipid kinase
G3580_RS12885	ENOG4105BZS	acriflavin resistance protein
G3580_RS12895	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G3580_RS12900	ENOG4105C02	permease
G3580_RS12915	ENOG4105DJ0	Poly(A) Polymerase
G3580_RS12920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3580_RS12930	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G3580_RS12935	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G3580_RS12945	ENOG41080XQ	Signal transduction protein with cbs domains
G3580_RS12950	ENOG4105DHQ	Histidine kinase
G3580_RS12955	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G3580_RS12980	ENOG4105DUM	transcriptional regulator, lysR family
G3580_RS12985	ENOG4105HMI	Membrane
G3580_RS13005	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G3580_RS13010	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
G3580_RS13015	ENOG4105CC0	LysR family Transcriptional regulator
G3580_RS13025	ENOG4105FG0	Nitroreductase
G3580_RS13030	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS13060	ENOG4105DDY	UPF0142 protein ycaO
G3580_RS13065	ENOG4105CD8	aminopeptidase N
G3580_RS13070	ENOG4108RAC	Rubrerythrin
G3580_RS13075	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G3580_RS13095	ENOG4105CVJ	phosphoglycerate mutase
G3580_RS13100	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G3580_RS13105	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G3580_RS13110	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G3580_RS13115	ENOG4105D06	uba thif-type nad fad binding protein
G3580_RS13125	ENOG4105CN1	protease
G3580_RS13135	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G3580_RS13145	ENOG4107YZP	Rhodanese domain protein
G3580_RS13150	ENOG4105VW4	glutaredoxin 3
G3580_RS13155	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
G3580_RS13165	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G3580_RS13170	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G3580_RS13175	ENOG4105MJ2	Competence protein
G3580_RS13180	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G3580_RS13185	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G3580_RS13200	ENOG4105D52	delta-aminolevulinic acid dehydratase
G3580_RS13205	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G3580_RS13215	ENOG4105ED9	Protein of unknown function (DUF455)
G3580_RS13220	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3580_RS13230	ENOG4108JU6	CBS domain protein
G3580_RS13235	ENOG4107QHF	type ii secretion system protein e
G3580_RS13260	ENOG4105C9M	aspartyl-trna synthetase
G3580_RS13280	ENOG4108TIT	dATP pyrophosphohydrolase
G3580_RS13285	ENOG4105VN1	Heat shock protein
G3580_RS13295	ENOG4105CAS	nag kinase
G3580_RS13310	ENOG4105CEY	Amp-dependent synthetase and ligase
G3580_RS13320	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G3580_RS13355	ENOG4105EXC	Acyl-transferase
G3580_RS13365	ENOG4105C11	sulfate adenylyltransferase), subunit 2
G3580_RS13370	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G3580_RS13375	ENOG4107QWE	)-transporter
G3580_RS13415	ENOG4105CPK	Glycosyl transferase (Group 1
G3580_RS13425	ENOG4105CAQ	asparagine synthetase
G3580_RS13455	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G3580_RS13470	ENOG4108QV3	biosynthesis protein
G3580_RS13495	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS13505	ENOG4108Z9W	Outer membrane porin
G3580_RS13515	ENOG4105C26	Dehydrogenase
G3580_RS13525	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G3580_RS13530	ENOG4105Y3Q	hemerythrin-like, metal-binding protein
G3580_RS13535	ENOG4105BZF	Glycosyl transferase (Group 1
G3580_RS13540	ENOG4105KB2	stringent starvation protein b
G3580_RS13545	ENOG4107MKT	Stringent starvation protein a
G3580_RS13550	ENOG4105EIX	cytochrome c1
G3580_RS13555	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G3580_RS13560	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G3580_RS13565	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G3580_RS13570	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G3580_RS13575	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G3580_RS13580	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G3580_RS13595	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G3580_RS13600	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G3580_RS13605	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G3580_RS13620	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G3580_RS13625	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
G3580_RS13635	ENOG4105EPW	hflc protein
G3580_RS13640	ENOG4107QJR	hflk protein
G3580_RS13645	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G3580_RS13650	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G3580_RS13655	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G3580_RS13670	ENOG4105CUT	histidyl-tRNA synthetase
G3580_RS13675	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G3580_RS13690	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G3580_RS13695	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G3580_RS13700	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G3580_RS13705	ENOG4105BZU	Histidine kinase
G3580_RS13710	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G3580_RS13720	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G3580_RS13730	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G3580_RS13735	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G3580_RS13740	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G3580_RS13745	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G3580_RS13750	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G3580_RS13755	ENOG4105BZU	Histidine kinase
G3580_RS13765	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G3580_RS13770	ENOG4107QSN	dihydrolipoamide acetyltransferase
G3580_RS13775	ENOG4107QN2	dihydrolipoyl dehydrogenase
G3580_RS13805	ENOG4105CEP	NADH dehydrogenase
G3580_RS13810	ENOG4105EPD	Oligopeptide transporter, Opt family
G3580_RS13820	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
G3580_RS13825	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS13830	ENOG4105BZU	Histidine kinase
G3580_RS13845	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS13870	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
G3580_RS13875	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
G3580_RS13880	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G3580_RS13900	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
G3580_RS13910	ENOG4105CUC	YeeE YedE family protein
G3580_RS13915	ENOG410870W	N-acetyltransferase
G3580_RS13930	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
G3580_RS13950	ENOG4105W2Z	cytochrome C, class I
G3580_RS13970	ENOG4107S7U	Sulfide dehydrogenase
G3580_RS13985	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G3580_RS13990	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G3580_RS13995	ENOG4105W5Q	DNA repair protein (RadC
G3580_RS14000	ENOG4105KDC	50s ribosomal protein l28
G3580_RS14010	ENOG4105VEQ	Cold shock protein
G3580_RS14015	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G3580_RS14020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G3580_RS14025	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
G3580_RS14030	ENOG4108I9X	Isocitrate lyase
G3580_RS14050	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G3580_RS14055	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G3580_RS14065	ENOG4106T14	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G3580_RS14085	ENOG4105BZU	Histidine kinase
G3580_RS14090	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G3580_RS14115	ENOG4105BZU	Histidine kinase
G3580_RS14120	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS14125	ENOG4105E2Z	phosphate ABC transporter (Permease
G3580_RS14130	ENOG4105C8U	phosphate abc transporter
G3580_RS14135	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G3580_RS14140	ENOG4105DFI	Membrane
G3580_RS14150	ENOG4105KHC	sulfurtransferase
G3580_RS14160	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G3580_RS14165	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
G3580_RS14170	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G3580_RS14175	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G3580_RS14180	ENOG4105K8N	protein family UPF0079, ATPase
G3580_RS14185	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G3580_RS14190	ENOG41067HS	methyltransferase
G3580_RS14200	ENOG4105DTN	riboflavin biosynthesis protein ribF
G3580_RS14205	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G3580_RS14210	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G3580_RS14215	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G3580_RS14220	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G3580_RS14230	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G3580_RS14240	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G3580_RS14245	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
G3580_RS14280	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G3580_RS14285	ENOG4105DR5	peptidase
G3580_RS14290	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
G3580_RS14295	ENOG4108UJD	30S ribosomal protein S9
G3580_RS14300	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G3580_RS14305	ENOG4108UKZ	OsmC family
G3580_RS14310	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
G3580_RS14320	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G3580_RS14325	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G3580_RS14330	ENOG4105E4C	Lytic transglycosylase catalytic
G3580_RS14350	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G3580_RS14365	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G3580_RS14375	ENOG4105EAH	synthase
G3580_RS14385	ENOG4105BZ7	extracellular solute-binding protein family 1
G3580_RS14395	ENOG4105BZU	Histidine kinase
G3580_RS14400	ENOG4105CPI	Metal Dependent Phosphohydrolase
G3580_RS14405	ENOG4105CPC	Aldo Keto reductase
G3580_RS14410	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
G3580_RS14415	ENOG4105C1J	atp-dependent rna helicase
G3580_RS14420	ENOG4105BZU	Histidine kinase
G3580_RS14425	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G3580_RS14430	ENOG4105W8H	transhydrogenase (subunit alpha
G3580_RS14435	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G3580_RS14440	ENOG4108ZF3	Phosphatase
G3580_RS14445	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
G3580_RS14450	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G3580_RS14455	ENOG4105EU8	FAD linked oxidase domain protein
G3580_RS14460	ENOG4105CQB	FAD linked oxidase domain protein
G3580_RS14465	ENOG4105JXH	GntR family transcriptional regulator
G3580_RS14475	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G3580_RS14480	ENOG4105K46	50S ribosomal protein l27
G3580_RS14485	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3580_RS14490	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G3580_RS14505	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
G3580_RS14535	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G3580_RS14540	ENOG41065U4	response regulator
G3580_RS14555	ENOG41085FR	LemA family
G3580_RS14565	ENOG4105C5H	ABC transporter
G3580_RS14575	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G3580_RS14585	ENOG4105E4C	Lytic transglycosylase catalytic
G3580_RS14600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS14605	ENOG4105BZU	Histidine kinase
G3580_RS14615	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS14630	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G3580_RS14635	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G3580_RS14640	ENOG4105VIE	preprotein translocase, subunit YajC
G3580_RS14645	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G3580_RS14655	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G3580_RS14670	ENOG4107QTF	adenylosuccinate lyase
G3580_RS14680	ENOG4107QHF	type ii secretion system protein e
G3580_RS14685	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
G3580_RS14690	ENOG4108UW8	fha domain-containing protein
G3580_RS14695	ENOG4108ZF3	Phosphatase
G3580_RS14700	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G3580_RS14705	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G3580_RS14725	ENOG4107QNR	UPF0135 protein
G3580_RS14730	ENOG4105C0H	protease
G3580_RS14735	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G3580_RS14740	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G3580_RS14750	ENOG4105K59	histidine triad (HIT) protein
G3580_RS14755	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
G3580_RS14760	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G3580_RS14765	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G3580_RS14770	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G3580_RS14775	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G3580_RS14780	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G3580_RS14785	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G3580_RS14790	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G3580_RS14795	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G3580_RS14800	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G3580_RS14810	ENOG4105E3A	(ABC) transporter
G3580_RS14815	ENOG4105DA5	(ABC) transporter
G3580_RS14835	ENOG4107PE3	Mammalian cell entry related domain protein
G3580_RS14840	ENOG4105CY3	ABC transporter, permease
G3580_RS14845	ENOG4105DHJ	ABC, transporter
G3580_RS14860	ENOG4105E4G	Type IV pilus
G3580_RS14870	ENOG4107QHF	type ii secretion system protein e
G3580_RS14900	ENOG4108VAU	general secretion pathway protein G
G3580_RS14925	ENOG4105C2X	Arabinose 5-phosphate isomerase
G3580_RS14935	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
G3580_RS14940	ENOG4105E39	Enoyl-CoA hydratase
G3580_RS14950	ENOG4105E9Q	Acyl-transferase
G3580_RS14955	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
G3580_RS14960	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G3580_RS14965	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
G3580_RS14975	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G3580_RS14980	ENOG4108JU5	Magnesium and cobalt efflux protein
G3580_RS14985	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G3580_RS14990	ENOG4105C9A	Phoh family
G3580_RS14995	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G3580_RS15010	ENOG41082AG	Plasmid maintenance system antidote protein
G3580_RS15025	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G3580_RS15030	ENOG4105BZS	acriflavin resistance protein
G3580_RS15035	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G3580_RS15040	ENOG4105TMB	Formate nitrite transporter
G3580_RS15045	ENOG4105D9P	serine threonine protein kinase
G3580_RS15055	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G3580_RS15060	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G3580_RS15065	ENOG4105C7B	Threonine dehydratase
G3580_RS15085	ENOG4107E2E	PKHD-type hydroxylase
G3580_RS15095	ENOG4108ESX	Receptor
G3580_RS15100	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G3580_RS15105	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G3580_RS15115	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
G3580_RS15125	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
G3580_RS15130	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G3580_RS15145	ENOG4105BZU	Histidine kinase
G3580_RS15160	ENOG4108TEB	UPF0114 protein
G3580_RS15185	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G3580_RS15195	ENOG4108JU3	Alkyl hydroperoxide reductase
G3580_RS15200	ENOG4105D3R	alkyl hydroperoxide reductase
G3580_RS15205	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G3580_RS15210	ENOG4105T95	Thiol disulfide interChange protein
G3580_RS15225	ENOG4105CA3	membrane-bound lytic murein transglycosylase
G3580_RS15235	ENOG4105M6F	mutator MutT protein
G3580_RS15240	ENOG4105CJW	magnesium transporter
G3580_RS15245	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G3580_RS15250	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
G3580_RS15255	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G3580_RS15265	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G3580_RS15275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS15280	ENOG4105CUX	Signal transduction histidine kinase
G3580_RS15300	ENOG41076HS	cation diffusion facilitator family transporter
G3580_RS15310	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G3580_RS15315	ENOG4105G2U	Cupin 2, conserved barrel domain protein
G3580_RS15320	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
G3580_RS15325	ENOG4105X23	Endonuclease Exonuclease phosphatase
G3580_RS15330	ENOG4105DZQ	phospholipase D Transphosphatidylase
G3580_RS15335	ENOG4105K4P	CoA-binding domain protein
G3580_RS15340	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G3580_RS15345	ENOG4105BZU	Histidine kinase
G3580_RS15350	ENOG4105C3G	gtp-binding protein
G3580_RS15355	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G3580_RS15360	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G3580_RS15365	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G3580_RS15375	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G3580_RS15380	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
G3580_RS15390	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G3580_RS15395	ENOG410890F	Dynamin family
G3580_RS15400	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G3580_RS15405	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G3580_RS15410	ENOG4106H78	methyltransferase
G3580_RS15415	ENOG4105C1V	Peptidase, M16
G3580_RS15430	ENOG4105CAK	Cell division ATP-binding protein ftsE
G3580_RS15435	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
G3580_RS15450	ENOG4107QN1	sodium solute
G3580_RS15455	ENOG4108IRC	dna polymerase iii
G3580_RS15460	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G3580_RS15465	ENOG4105BZU	Histidine kinase
G3580_RS15475	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G3580_RS15520	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G3580_RS15530	ENOG4105CXN	decarboxylase
G3580_RS15535	ENOG4105DHP	deoxycytidine triphosphate deaminase
G3580_RS15550	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G3580_RS15560	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
G3580_RS15565	ENOG4105CHH	sulfate transporter
G3580_RS15570	ENOG4105BZU	Histidine kinase
G3580_RS15580	ENOG4105RAK	Histidine kinase
G3580_RS15585	ENOG4105BZU	Histidine kinase
G3580_RS15590	ENOG4108N2Y	auxin Efflux
G3580_RS15605	ENOG4105EQ1	Transcriptional regulator
G3580_RS15610	ENOG4105BZU	Histidine kinase
G3580_RS15620	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
G3580_RS15625	ENOG4105HDD	phospholipase
G3580_RS15630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS15635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS15650	ENOG4105C6K	Malic enzyme
G3580_RS15655	ENOG4107QJE	Chromosome Partitioning Protein
G3580_RS15665	ENOG4105KA7	cytochrome C
G3580_RS15670	ENOG4108VYJ	response regulator receiver protein
G3580_RS15675	ENOG4105C4R	Atp-dependent dna helicase
G3580_RS15685	ENOG4105C8T	Leucyl-tRNA synthetase
G3580_RS15695	ENOG4105DJF	DNA polymerase III, delta' subunit
G3580_RS15700	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G3580_RS15715	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G3580_RS15720	ENOG4108Z66	YbaK ebsC protein
G3580_RS15725	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
G3580_RS15735	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G3580_RS15740	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G3580_RS15745	ENOG4105VCC	30S ribosomal protein S21
G3580_RS15760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G3580_RS15770	ENOG4105BZU	Histidine kinase
G3580_RS15775	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS15780	ENOG4105BZU	Histidine kinase
G3580_RS15795	ENOG4105CEV	competence damage-inducible protein
G3580_RS15805	ENOG4105CQ7	ATP-dependent helicase
G3580_RS15810	ENOG4107Z6W	Protein CrcB homolog
G3580_RS15825	ENOG4105BZU	Histidine kinase
G3580_RS15830	ENOG4105BZU	Histidine kinase
G3580_RS15840	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G3580_RS15845	ENOG4105D05	Receptor
G3580_RS15850	ENOG4105CX6	glutaminyL-tRNA synthetase
G3580_RS15860	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G3580_RS15865	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS15870	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS15875	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS15885	ENOG4105D65	subunit l
G3580_RS15895	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G3580_RS15900	ENOG4108JPZ	Monovalent cation H antiporter subunit D
G3580_RS15905	ENOG4105MKQ	Monovalent cation H antiporter subunit C
G3580_RS15930	ENOG4105C5I	Dehydrogenase
G3580_RS15935	ENOG4108FUF	Transcriptional regulator, IclR family
G3580_RS15940	ENOG41061WM	D-Alanyl-D-Alanine
G3580_RS15950	ENOG4105C6K	Malic enzyme
G3580_RS15955	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G3580_RS15965	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
G3580_RS15970	ENOG4109066	lysm domain bon superfamily protein
G3580_RS15980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS15985	ENOG4107TUY	Histidine kinase
G3580_RS15995	ENOG4105CHM	Aminotransferase
G3580_RS16000	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
G3580_RS16005	ENOG4107W7X	Aldolase
G3580_RS16020	ENOG4105BZU	Histidine kinase
G3580_RS16030	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G3580_RS16035	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G3580_RS16040	ENOG4105BZU	Histidine kinase
G3580_RS16045	ENOG4108MTB	glycosyl transferase family
G3580_RS16060	ENOG4107RNH	Outer membrane receptor FepA
G3580_RS16075	ENOG4105HEE	Binding Domain protein
G3580_RS16085	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G3580_RS16090	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G3580_RS16095	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
G3580_RS16100	ENOG4107R3J	Transporter
G3580_RS16130	ENOG4105D7T	ABC transporter
G3580_RS16140	ENOG4105D7T	ABC transporter
G3580_RS16145	ENOG4105ETX	regulatoR
G3580_RS16155	ENOG4105BZU	Histidine kinase
G3580_RS16175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G3580_RS16180	ENOG4105ES5	Histidine kinase
G3580_RS16190	ENOG4105DR5	peptidase
G3580_RS16195	ENOG4105CUZ	uba thif-type nad fad binding protein
G3580_RS16215	ENOG4105C87	Aminotransferase class I and II
G3580_RS16225	ENOG4108UUM	single-stranded DNA-binding protein
G3580_RS16230	ENOG4107RDB	Major Facilitator
G3580_RS16235	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G3580_RS16250	ENOG4105CMR	udp-glucose 4-epimerase
G3580_RS16255	ENOG41080T7	secreted protein
G3580_RS16260	ENOG4105TX3	Histidine kinase
G3580_RS16270	ENOG4105VEJ	Heat shock protein
G3580_RS16275	ENOG4108ZT0	50S ribosomal protein l17
G3580_RS16280	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G3580_RS16285	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G3580_RS16290	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G3580_RS16295	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3580_RS16300	ENOG41067V7	50S ribosomal protein L36
G3580_RS16305	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G3580_RS16310	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G3580_RS16315	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G3580_RS16320	ENOG4105VPB	50S ribosomal protein L30
G3580_RS16325	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G3580_RS16330	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G3580_RS16335	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G3580_RS16340	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G3580_RS16345	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G3580_RS16350	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3580_RS16355	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G3580_RS16365	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G3580_RS16370	ENOG41083MP	50s ribosomal protein l29
G3580_RS16375	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G3580_RS16380	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G3580_RS16385	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G3580_RS16390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G3580_RS16395	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3580_RS16400	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G3580_RS16405	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G3580_RS16410	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G3580_RS16415	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G3580_RS16420	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G3580_RS16425	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G3580_RS16430	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G3580_RS16435	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G3580_RS16440	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G3580_RS16445	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G3580_RS16450	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G3580_RS16455	ENOG4108VZM	50s ribosomal protein L10
G3580_RS16460	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G3580_RS16465	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G3580_RS16475	ENOG4105PM1	preprotein translocase subunit SecE
G3580_RS16485	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G3580_RS16525	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G3580_RS16535	ENOG4105BZU	Histidine kinase
G3580_RS16565	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G3580_RS16570	ENOG4105DZS	Phenylacetate-CoA ligase
G3580_RS16575	ENOG4108IV0	ABC, transporter
G3580_RS16590	ENOG4105C32	Amino acid ABC transporter (Permease)
G3580_RS16595	ENOG4105C0Z	ABC transporter
G3580_RS16600	ENOG4108IQE	Amp-dependent synthetase and ligase
G3580_RS16615	ENOG4107S2Z	UPF0761 membrane protein
G3580_RS16625	ENOG4106VK6	Flagellar motor protein
G3580_RS16655	ENOG4108UMR	transcriptional regulator AsnC family
G3580_RS16670	ENOG4106P6N	cytochrome d1 heme region
G3580_RS16680	ENOG4105W2Z	cytochrome C, class I
G3580_RS16685	ENOG4105F64	nitrite reductase
G3580_RS16690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G3580_RS16715	ENOG4108T0W	nitrous oxide maturation protein NosY
G3580_RS16720	ENOG4105CIG	ABC transporter
G3580_RS16725	ENOG4105DH4	Periplasmic copper-binding protein
G3580_RS16735	ENOG4105HEE	Binding Domain protein
G3580_RS16745	ENOG4108VKQ	nitriC oxide reductase
G3580_RS16750	ENOG4105DSQ	Nitric oxide reductase
G3580_RS16755	ENOG4105CBC	glutamate synthase
G3580_RS16760	ENOG4105C7K	acetolactate synthase
G3580_RS16775	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
G3580_RS16805	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
G3580_RS16810	ENOG4105BZU	Histidine kinase
G3580_RS16815	ENOG4105BZU	Histidine kinase
G3580_RS16890	ENOG4108RXX	maleylacetoacetate isomerase
G3580_RS16900	ENOG4105F1J	Homogentisate 1,2-dioxygenase
G3580_RS16905	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G3580_RS16920	ENOG41090VV	Protein of unknown function (DUF2846)
G3580_RS16945	ENOG4105D5P	Methylmalonyl-coA mutase
G3580_RS16960	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G3580_RS16975	ENOG4105CR8	Transcriptional regulator
G3580_RS16980	ENOG4105EQ0	Major Facilitator superfamily
G3580_RS16990	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G3580_RS17000	ENOG4107QX3	carboxylase
G3580_RS17005	ENOG4105DJT	lAO AO transport system ATPase
G3580_RS17015	ENOG4105DRR	Transcriptional regulator, GntR family
G3580_RS17020	ENOG4105E39	Enoyl-CoA hydratase
G3580_RS17025	ENOG4105D64	Mechanosensitive ion channel
G3580_RS17045	ENOG4105HF0	Membrane
G3580_RS17065	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS17070	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS17095	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G3580_RS17100	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G3580_RS17105	ENOG4105EFT	decarboxylase
G3580_RS17110	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G3580_RS17120	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G3580_RS17125	ENOG41090ED	Protein with unknown function (DUF469)
G3580_RS17130	ENOG4108ESY	Metal dependent phosphohydrolase
G3580_RS17140	ENOG4108VWS	Yaeq family
G3580_RS17145	ENOG4105C1J	atp-dependent rna helicase
G3580_RS17150	ENOG4108Z7G	MaoC domain protein dehydratase
G3580_RS17155	ENOG4105K70	DNA-binding protein
G3580_RS17165	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
G3580_RS17170	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS17180	ENOG4105CH5	extracellular solute-binding protein, family 7
G3580_RS17185	ENOG4108JUA	Transcriptional regulator
G3580_RS17195	ENOG4105EJC	lysr family transcriptional regulator
G3580_RS17235	ENOG4105GRZ	Ycii-related protein
G3580_RS17240	ENOG4105CHP	RNA polymerase
G3580_RS17260	ENOG4105CNG	UPF0061 protein
G3580_RS17295	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G3580_RS17305	ENOG4105BZU	Histidine kinase
G3580_RS17310	ENOG4105BZU	Histidine kinase
G3580_RS17320	ENOG4105BZU	Histidine kinase
G3580_RS17340	ENOG4105BZU	Histidine kinase
G3580_RS17345	ENOG4105EW9	transcriptional regulator AsnC family
G3580_RS17350	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G3580_RS17355	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G3580_RS17375	ENOG4105BZU	Histidine kinase
G3580_RS17380	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS17420	ENOG4105WH1	Two component transcriptional regulator luxr family
G3580_RS17425	ENOG4105BZU	Histidine kinase
G3580_RS17430	ENOG41076YT	nitrate reductase, gamma subunit
G3580_RS17435	ENOG4105R3A	Nitrate reductase
G3580_RS17440	ENOG4108IUE	nitrate reductase beta subunit
G3580_RS17445	ENOG4105CRU	nitrate reductase, alpha subunit
G3580_RS17450	ENOG4105DQQ	Major facilitator superfamily MFS_1
G3580_RS17470	ENOG4108UXE	Protein tyrosine phosphatase
G3580_RS17475	ENOG4105D6J	arsenicaL-resistance protein
G3580_RS17485	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
G3580_RS17490	ENOG4105C26	Dehydrogenase
G3580_RS17515	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G3580_RS17520	ENOG4105DHQ	Histidine kinase
G3580_RS17525	ENOG4105C0H	protease
G3580_RS17540	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS17545	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS17560	ENOG4105D4A	Cell wall formation (By similarity)
G3580_RS17585	ENOG4105C5H	ABC transporter
G3580_RS17610	ENOG4105C5H	ABC transporter
G3580_RS17620	ENOG4108IJ7	Glycine betaine
G3580_RS17625	ENOG4108HQS	Glycine betaine
G3580_RS17630	ENOG4105GIJ	Glycine betaine
G3580_RS17635	ENOG4108594	Permease of the drug metabolite transporter
G3580_RS17640	ENOG4108NIW	Leucine export protein LeuE
G3580_RS17655	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G3580_RS17665	ENOG4105ETT	transcriptional Regulator, LysR family
G3580_RS17675	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
G3580_RS17690	ENOG4107TVC	Glycosyl transferase, family 2
G3580_RS17700	ENOG4108WZM	domain protein
G3580_RS17720	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G3580_RS17725	ENOG4105C3R	Methionine synthase
G3580_RS17745	ENOG4105CPI	Metal Dependent Phosphohydrolase
G3580_RS17770	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
G3580_RS17800	ENOG4108Z4U	Ferredoxin
G3580_RS17815	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G3580_RS17830	ENOG4105HMI	Membrane
G3580_RS17835	ENOG4105DUM	transcriptional regulator, lysR family
G3580_RS17855	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G3580_RS17860	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
G3580_RS17865	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
G3580_RS17870	ENOG4105DX0	Hemolysin A
G3580_RS17875	ENOG4105SYT	Methylenetetrahydrofolate reductase
G3580_RS17880	ENOG4105BZU	Histidine kinase
G3580_RS17900	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
G3580_RS17925	ENOG4106UX7	integral membrane protein
G3580_RS17950	ENOG4105D7A	ATP-binding protein
G3580_RS17960	ENOG4105CDY	transcriptional regulatory protein
G3580_RS17965	ENOG4105C32	Amino acid ABC transporter (Permease)
G3580_RS17970	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G3580_RS17975	ENOG4105C0Z	ABC transporter
G3580_RS17980	ENOG4108IV0	ABC, transporter
G3580_RS17990	ENOG4105ECQ	AraC Family Transcriptional Regulator
G3580_RS18030	ENOG4108ZJF	Glcg protein
G3580_RS18050	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
G3580_RS18090	ENOG4105C2C	drug resistance transporter, Bcr CflA
G3580_RS18095	ENOG4105C0P	Mg chelatase subunit ChlI
G3580_RS18180	ENOG41079K6	HNH endonuclease
G3580_RS18255	ENOG4107QHF	type ii secretion system protein e
G3580_RS18265	ENOG4108VAU	general secretion pathway protein G
G3580_RS18300	ENOG4105GVR	general secretion pathway protein D
G3580_RS18315	ENOG4105CMM	transposase
G3580_RS18350	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G3580_RS18355	ENOG4105W0Z	cytoplasmic protein
G3580_RS18365	ENOG4108YZA	Nitrogen regulatory protein pii
G3580_RS18370	ENOG4105BZU	Histidine kinase
G3580_RS18385	ENOG4105CIY	formyltetrahydrofolate deformylase
G3580_RS18390	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
G3580_RS18400	ENOG4105DWV	Homoserine O-trans-acetylase
G3580_RS18405	ENOG4105DWV	Homoserine O-trans-acetylase
G3580_RS18410	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G3580_RS18415	ENOG41080Z8	PHOSPHOCARRIER protein
G3580_RS18420	ENOG4105YHU	PTS system
G3580_RS18425	ENOG41081YB	ApbE family
G3580_RS18435	ENOG4108M3P	Membrane
G3580_RS18440	ENOG4105D7Z	glutathione synthase
G3580_RS18455	ENOG4105EB3	Histidine kinase
G3580_RS18470	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G3580_RS18480	ENOG4108U4N	(sortase) family
G3580_RS18485	ENOG4107RZC	phospholipase d
G3580_RS18490	ENOG4107R7Y	intracellular protease Pfpi family
G3580_RS18510	ENOG4108M1T	Cytochrome c-type biogenesis protein
G3580_RS18515	ENOG4105KWW	Biogenesis protein
G3580_RS18520	ENOG4107QX9	Thiol disulfide interChange protein
G3580_RS18525	ENOG4105DA4	cytochrome c-type biogenesis protein
G3580_RS18530	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
G3580_RS18540	ENOG41060IM	Heme exporter protein
G3580_RS18545	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
G3580_RS18550	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
G3580_RS18555	ENOG4105BZU	Histidine kinase
G3580_RS18560	ENOG4108K3Z	AraC family transcriptional regulator
G3580_RS18570	ENOG4105DWV	Homoserine O-trans-acetylase
G3580_RS18575	ENOG4105CUW	cytochrome C-TYPE protein
G3580_RS18585	ENOG4105GXZ	Ferredoxin-type protein NapH
G3580_RS18590	ENOG4108BGM	Quinol dehydrogenase periplasmic component
G3580_RS18595	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G3580_RS18605	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G3580_RS18610	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
G3580_RS18620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G3580_RS18625	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G3580_RS18630	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G3580_RS18640	ENOG4105C3J	Cysteine desulfurase
G3580_RS18645	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G3580_RS18650	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
G3580_RS18655	ENOG4105CC0	LysR family Transcriptional regulator
G3580_RS18700	ENOG4108UR2	Nitrogen fixation protein NifX
G3580_RS18705	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
G3580_RS18710	ENOG4105D0B	Nitrogenase protein alpha chain
G3580_RS18740	ENOG4105VDB	UPF0125 protein
G3580_RS18745	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
G3580_RS18755	ENOG4105D6A	Electron transport complex
G3580_RS18765	ENOG4108R3D	Electron transport complex
G3580_RS18770	ENOG4105DGN	Electron transport complex
G3580_RS18775	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
G3580_RS18780	ENOG4108JUA	Transcriptional regulator
G3580_RS18825	ENOG4105NZG	Ferredoxin
G3580_RS18845	ENOG4105F4R	Transcriptional regulator mode
G3580_RS18850	ENOG4105F4R	Transcriptional regulator mode
G3580_RS18855	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G3580_RS18860	ENOG4107XWS	modD protein
G3580_RS18870	ENOG4105E0C	molybdate abc transporter
G3580_RS18875	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G3580_RS18890	ENOG4105CC0	LysR family Transcriptional regulator
G3580_RS18910	ENOG4105E3I	toluene tolerance
G3580_RS18935	ENOG4105BZU	Histidine kinase
G3580_RS18940	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
G3580_RS18945	ENOG4105P1D	4fe-4s ferredoxin, iron-sulfur binding
G3580_RS18950	ENOG4105ND9	Nitrogenase-associated protein
G3580_RS18955	ENOG4105CNW	domain protein
G3580_RS18960	ENOG4105KXW	Ferredoxin
G3580_RS18965	ENOG4105U82	Ferredoxin
G3580_RS18975	ENOG41065RQ	ADP-ribosylation crystallin J1
G3580_RS18985	ENOG4105WKW	Pfam:DUF1458
G3580_RS19025	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
G3580_RS19050	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
G3580_RS19055	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
G3580_RS19060	ENOG4105D0B	Nitrogenase protein alpha chain
G3580_RS19065	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
G3580_RS19075	ENOG4107IVC	4Fe-4S ferredoxin, iron-sulfur binding
G3580_RS19080	ENOG4105FZE	dinitrogenase iron-molybdenum cofactor biosynthesis
G3580_RS19100	ENOG4106HK8	GPR1 FUN34 yaaH family protein
G3580_RS19115	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
G3580_RS19125	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G3580_RS19140	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
G3580_RS19145	ENOG4105XV5	nifz family
G3580_RS19150	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G3580_RS19160	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G3580_RS19175	ENOG4105C2C	drug resistance transporter, Bcr CflA
G3580_RS19180	ENOG4105EHZ	conserved protein UCP016719
G3580_RS19200	ENOG41085JF	Trap dicarboxylate transporter-dctp subunit
G3580_RS19210	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G3580_RS19240	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
G3580_RS19250	ENOG4105DHU	Bile acid
G3580_RS19265	ENOG4105CK7	Sodium proline symporter
G3580_RS19330	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G3580_RS19340	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G3580_RS19345	ENOG4105DJ4	phosphatidylserine decarboxylase
G3580_RS19375	ENOG4105D3G	Pseudouridine synthase
G3580_RS19380	ENOG4108VYJ	response regulator receiver protein
G3580_RS19390	ENOG4105KPV	Transcriptional regulator
G3580_RS19400	ENOG4108Z4U	Ferredoxin
G3580_RS19420	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G3580_RS19425	ENOG4105BZU	Histidine kinase
G3580_RS19430	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G3580_RS19435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G3580_RS19440	ENOG4105P4J	Allophanate hydrolase, subunit 1
G3580_RS19445	ENOG4107R7A	Allophanate hydrolase subunit 2
G3580_RS19450	ENOG4105E7W	lamb ycsf family protein
G3580_RS19460	ENOG4108V5V	Serine Threonine protein kinase
G3580_RS19470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G3580_RS19520	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G3580_RS19535	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G3580_RS19545	ENOG4105CBX	hi0933 family
G3580_RS19565	ENOG4108UPT	UPF0178 protein
G3580_RS19570	ENOG4108ZG0	Ompa motb domain protein
G3580_RS19580	ENOG4107SDU	Methyl-accepting chemotaxis
G3580_RS19590	ENOG4105DH7	May be involved in recombination (By similarity)
G3580_RS19600	ENOG4105I08	Pseudouridine synthase
G3580_RS19615	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G3580_RS19620	ENOG4105W7K	Transcriptional regulator
G3580_RS19630	ENOG4105C4W	S-formylglutathione hydrolase
G3580_RS19640	ENOG4105EYM	Major Facilitator superfamily
G3580_RS19655	ENOG4105DKQ	ROK family
G3580_RS19660	ENOG4108RPX	mosc domain containing protein
G3580_RS19670	ENOG4105C25	Primosomal protein n'
G3580_RS19675	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G3580_RS19680	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G3580_RS19685	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G3580_RS19690	ENOG4105C1A	potassium transporter peripheral membrane
G3580_RS19695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G3580_RS19700	ENOG4105ES5	Histidine kinase
G3580_RS19710	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G3580_RS19715	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
G3580_RS19720	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G3580_RS19730	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G3580_RS19735	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G3580_RS19740	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G3580_RS19745	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)