locus-tag	class	description
AZC_RS00005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZC_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZC_RS00015	COG0424	maF-like protein
AZC_RS00020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZC_RS00025	COG0237	dephospho-CoA kinase activity
AZC_RS00030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZC_RS00045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_RS00050	COG1702	phosphate starvation-inducible protein PhoH
AZC_RS00055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZC_RS00060	COG1253	flavin adenine dinucleotide binding
AZC_RS00065	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZC_RS00070	COG1396	sequence-specific DNA binding
AZC_RS00075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZC_RS00080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZC_RS00090	COG0779	Required for maturation of 30S ribosomal subunits
AZC_RS00105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZC_RS00110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZC_RS00115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZC_RS00125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS00140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZC_RS00150	COG0604	alcohol dehydrogenase
AZC_RS00170	COG2030	dehydratase
AZC_RS00175	COG0625	glutathione transferase activity
AZC_RS00185	COG0604	alcohol dehydrogenase
AZC_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS00185	COG3321	synthase
AZC_RS00190	COG0156	8-amino-7-oxononanoate synthase activity
AZC_RS00195	COG0300	oxidoreductase activity
AZC_RS00290	COG2096	Adenosyltransferase
AZC_RS00315	COG1185	polyribonucleotide nucleotidyltransferase activity
AZC_RS00320	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZC_RS00330	COG2072	flavoprotein involved in K transport
AZC_RS00340	COG0438	transferase activity, transferring glycosyl groups
AZC_RS00345	COG2144	transferase activity, transferring acyl groups
AZC_RS00370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_RS00390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZC_RS00395	COG0352	thiamine-phosphate diphosphorylase activity
AZC_RS00400	COG0247	lactate metabolic process
AZC_RS00405	COG2852	Protein conserved in bacteria
AZC_RS00410	COG0277	FAD linked oxidase domain protein
AZC_RS00415	COG0277	FAD linked oxidase domain protein
AZC_RS00420	COG0583	DNA-binding transcription factor activity
AZC_RS00455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_RS00455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_RS00475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZC_RS00480	COG1674	ftsk spoiiie
AZC_RS00485	COG0436	Aminotransferase
AZC_RS00490	COG0196	riboflavin kinase activity
AZC_RS00505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZC_RS00510	COG2183	response to ionizing radiation
AZC_RS00515	COG1794	racemase activity, acting on amino acids and derivatives
AZC_RS00520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AZC_RS00525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AZC_RS00535	COG2271	Major facilitator Superfamily
AZC_RS00540	COG0242	peptide deformylase activity
AZC_RS00545	COG1201	RNA secondary structure unwinding
AZC_RS00565	COG1902	pentaerythritol trinitrate reductase activity
AZC_RS00585	COG4566	intracellular signal transduction
AZC_RS00590	COG0281	malic enzyme
AZC_RS00595	COG2985	domain, Protein
AZC_RS00605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZC_RS00620	COG4191	Histidine kinase
AZC_RS00630	COG0583	DNA-binding transcription factor activity
AZC_RS00640	COG4172	Belongs to the ABC transporter superfamily
AZC_RS00655	COG4239	(ABC) transporter, permease
AZC_RS00660	COG4174	ABC transporter (Permease)
AZC_RS00665	COG4166	transmembrane transport
AZC_RS00670	COG4166	transmembrane transport
AZC_RS00675	COG3474	cytochrome
AZC_RS00680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZC_RS00685	COG0077	Prephenate dehydratase
AZC_RS00685	COG1605	Chorismate mutase
AZC_RS00695	COG2816	NAD+ diphosphatase activity
AZC_RS00710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZC_RS00720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZC_RS00735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZC_RS00750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZC_RS00785	COG0588	phosphoglycerate mutase activity
AZC_RS00790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZC_RS00800	COG0284	orotidine-5'-phosphate decarboxylase activity
AZC_RS00810	COG3963	phosphatidate phosphatase activity
AZC_RS00815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZC_RS00825	COG2951	lytic endotransglycosylase activity
AZC_RS00875	COG3395	kinase activity
AZC_RS00880	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZC_RS00885	COG1454	alcohol dehydrogenase
AZC_RS00890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS00895	COG2271	Major facilitator Superfamily
AZC_RS00900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_RS00915	COG4774	siderophore transport
AZC_RS00920	COG1120	ATPase activity
AZC_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_RS00930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_RS00955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZC_RS00960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_RS00975	COG4191	Histidine kinase
AZC_RS00980	COG4566	intracellular signal transduction
AZC_RS00985	COG2072	flavoprotein involved in K transport
AZC_RS01030	COG0583	DNA-binding transcription factor activity
AZC_RS01035	COG1733	regulation of RNA biosynthetic process
AZC_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS01045	COG1733	regulation of RNA biosynthetic process
AZC_RS01055	COG1335	isochorismatase
AZC_RS01075	COG2171	N-acyltransferase activity
AZC_RS01105	COG0006	proline dipeptidase activity
AZC_RS01120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZC_RS01125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZC_RS01135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_RS01140	COG2226	methyltransferase
AZC_RS01150	COG0251	oxidation-reduction process
AZC_RS01155	COG2813	Specifically methylates the guanine in position
AZC_RS01155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS01160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS01180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZC_RS01190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZC_RS01190	COG1648	precorrin-2 dehydrogenase activity
AZC_RS01210	COG4957	zinc ion binding
AZC_RS01215	COG0842	Transport permease protein
AZC_RS01220	COG1131	(ABC) transporter
AZC_RS01225	COG1522	sequence-specific DNA binding
AZC_RS01235	COG0400	carboxylic ester hydrolase activity
AZC_RS01240	COG0346	lactoylglutathione lyase activity
AZC_RS01250	COG0583	DNA-binding transcription factor activity
AZC_RS01255	COG0625	glutathione transferase activity
AZC_RS01275	COG1573	uracil-dna glycosylase
AZC_RS01290	COG0840	transmembrane signaling receptor activity
AZC_RS01295	COG0471	metal ion transport
AZC_RS01305	COG0481	GTPase activity
AZC_RS01330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZC_RS01335	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZC_RS01340	COG2329	Antibiotic biosynthesis monooxygenase
AZC_RS01350	COG1522	sequence-specific DNA binding
AZC_RS01355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZC_RS01410	COG4251	negative regulation of phosphorylation
AZC_RS01410	COG3706	GGDEF domain
AZC_RS01410	COG5001	Diguanylate cyclase
AZC_RS01410	COG2203	Gaf domain
AZC_RS01415	COG0791	NLP P60 protein
AZC_RS01420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZC_RS01435	COG0583	DNA-binding transcription factor activity
AZC_RS01440	COG2814	Major facilitator Superfamily
AZC_RS01450	COG1643	Atp-dependent helicase
AZC_RS01460	COG4689	acetoacetate decarboxylase
AZC_RS01480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_RS01485	COG0697	spore germination
AZC_RS01530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_RS01535	COG4150	thiosulfate binding
AZC_RS01540	COG3411	Ferredoxin
AZC_RS01545	COG0473	3-isopropylmalate dehydrogenase activity
AZC_RS01560	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AZC_RS01575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZC_RS01585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZC_RS01590	COG1309	transcriptional regulator
AZC_RS01600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZC_RS01615	COG0824	Thioesterase
AZC_RS01635	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS01645	COG2358	TRAP transporter, solute receptor (TAXI family
AZC_RS01685	COG1217	gtp-binding protein TYPA
AZC_RS01695	COG0019	diaminopimelate decarboxylase activity
AZC_RS01700	COG0156	8-amino-7-oxononanoate synthase activity
AZC_RS01715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZC_RS01720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZC_RS01730	COG2814	Major facilitator Superfamily
AZC_RS01740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZC_RS01745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_RS01770	COG0069	glutamate synthase activity
AZC_RS01785	COG5002	protein histidine kinase activity
AZC_RS01825	COG0784	Response regulator, receiver
AZC_RS01835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZC_RS01875	COG0840	transmembrane signaling receptor activity
AZC_RS01875	COG3290	protein histidine kinase activity
AZC_RS01885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZC_RS01895	COG0400	carboxylic ester hydrolase activity
AZC_RS01905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZC_RS01925	COG1999	signal sequence binding
AZC_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS01945	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AZC_RS01960	COG0450	alkyl hydroperoxide reductase
AZC_RS01975	COG0534	Mate efflux family protein
AZC_RS01995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_RS02010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZC_RS02010	COG1793	dna ligase
AZC_RS02030	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AZC_RS02050	COG0354	folic acid binding
AZC_RS02055	COG2818	Glycosylase
AZC_RS02075	COG0456	acetyltransferase
AZC_RS02080	COG0009	L-threonylcarbamoyladenylate synthase
AZC_RS02090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZC_RS02090	COG0574	Belongs to the PEP-utilizing enzyme family
AZC_RS02105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS02110	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZC_RS02145	COG1733	regulation of RNA biosynthetic process
AZC_RS02150	COG2910	NAD(P)H-binding
AZC_RS02160	COG0459	protein refolding
AZC_RS02165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZC_RS02235	COG2989	Protein conserved in bacteria
AZC_RS02240	COG3108	Peptidase M15
AZC_RS02245	COG3750	Belongs to the UPF0335 family
AZC_RS02270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZC_RS02275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZC_RS02295	COG0583	DNA-binding transcription factor activity
AZC_RS02305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZC_RS02320	COG1194	a g-specific adenine glycosylase
AZC_RS02340	COG0070	glutamate synthase
AZC_RS02340	COG0069	glutamate synthase activity
AZC_RS02340	COG0067	glutamate synthase
AZC_RS02350	COG1238	metal cluster binding
AZC_RS02355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZC_RS02360	COG1414	Transcriptional regulator
AZC_RS02370	COG1802	Transcriptional regulator
AZC_RS02380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS02395	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS02400	COG0488	(ABC) transporter
AZC_RS02425	COG0683	leucine binding
AZC_RS02445	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS02450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AZC_RS02455	COG1877	trehalose-phosphatase activity
AZC_RS02470	COG0678	peroxiredoxin activity
AZC_RS02480	COG1678	Uncharacterized ACR, COG1678
AZC_RS02490	COG3321	synthase
AZC_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS02490	COG0604	alcohol dehydrogenase
AZC_RS02505	COG0254	rRNA binding
AZC_RS02510	COG1132	(ABC) transporter
AZC_RS02520	COG1360	Flagellar Motor Protein
AZC_RS02530	COG0483	inositol monophosphate 1-phosphatase activity
AZC_RS02540	COG0352	thiamine-phosphate diphosphorylase activity
AZC_RS02545	COG3588	fructose-bisphosphate aldolase
AZC_RS02550	COG0126	phosphoglycerate kinase activity
AZC_RS02580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZC_RS02585	COG1692	metallophosphoesterase
AZC_RS02590	COG0217	transcriptional regulatory protein
AZC_RS02595	COG0789	Transcriptional regulator
AZC_RS02605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZC_RS02615	COG0632	four-way junction helicase activity
AZC_RS02635	COG2255	four-way junction helicase activity
AZC_RS02640	COG0824	Thioesterase
AZC_RS02660	COG0823	Involved in the tonB-independent uptake of proteins
AZC_RS02665	COG2885	chlorophyll binding
AZC_RS02675	COG0037	tRNA processing
AZC_RS02680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZC_RS02685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZC_RS02690	COG0305	Participates in initiation and elongation during chromosome replication
AZC_RS02700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_RS02710	COG1286	toxin biosynthetic process
AZC_RS02715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZC_RS02720	COG4221	oxidoreductase activity
AZC_RS02725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZC_RS02730	COG2161	toxin-antitoxin pair type II binding
AZC_RS02735	COG4115	mRNA cleavage
AZC_RS02740	COG2927	DNA polymerase III (CHI subunit)
AZC_RS02765	COG0657	acetylesterase activity
AZC_RS02770	COG0432	Pfam Uncharacterised protein family UPF0047
AZC_RS02780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZC_RS02785	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AZC_RS02790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_RS02800	COG3264	Mechanosensitive ion channel
AZC_RS02800	COG1196	nuclear chromosome segregation
AZC_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_RS02815	COG0604	alcohol dehydrogenase
AZC_RS02830	COG0693	protein deglycase activity
AZC_RS02845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZC_RS02850	COG0800	Aldolase
AZC_RS02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZC_RS02865	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZC_RS02870	COG0523	cobalamin synthesis protein
AZC_RS02880	COG0495	leucyl-tRNA aminoacylation
AZC_RS02900	COG2223	nitrite transmembrane transporter activity
AZC_RS02925	COG1960	acyl-CoA dehydrogenase activity
AZC_RS02935	COG0667	Aldo Keto reductase
AZC_RS02940	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS02955	COG4988	ABC transporter
AZC_RS02960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AZC_RS02970	COG1294	oxidase, subunit
AZC_RS02975	COG2824	Alkylphosphonate utilization operon protein PhnA
AZC_RS02995	COG3246	L-lysine catabolic process to acetate
AZC_RS03000	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZC_RS03010	COG4191	Histidine kinase
AZC_RS03040	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZC_RS03075	COG0375	protein maturation
AZC_RS03085	COG2204	response regulator
AZC_RS03150	COG2203	Gaf domain
AZC_RS03150	COG2200	EAL domain
AZC_RS03150	COG2199	diguanylate cyclase activity
AZC_RS03155	COG0745	RESPONSE REGULATOR receiver
AZC_RS03165	COG0745	RESPONSE REGULATOR receiver
AZC_RS03170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZC_RS03190	COG1360	Flagellar Motor Protein
AZC_RS03205	COG1338	Plays a role in the flagellum-specific transport system
AZC_RS03215	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZC_RS03225	COG1706	bacterial-type flagellum-dependent cell motility
AZC_RS03230	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AZC_RS03235	COG4786	Flagellar basal body rod
AZC_RS03240	COG1677	Flagellar hook-basal body complex protein FliE
AZC_RS03245	COG1558	bacterial-type flagellum-dependent cell motility
AZC_RS03250	COG1815	bacterial-type flagellum-dependent cell motility
AZC_RS03260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZC_RS03265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZC_RS03270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZC_RS03285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZC_RS03290	COG4786	Flagellar basal body rod
AZC_RS03295	COG1157	protein secretion by the type III secretion system
AZC_RS03320	COG5443	negative regulation of bacterial-type flagellum assembly
AZC_RS03325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZC_RS03330	COG1987	bacterial-type flagellum assembly
AZC_RS03335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZC_RS03370	COG0643	Histidine kinase
AZC_RS03370	COG2198	Histidine kinase
AZC_RS03370	COG0784	Response regulator, receiver
AZC_RS03375	COG0835	chemotaxis
AZC_RS03380	COG0745	RESPONSE REGULATOR receiver
AZC_RS03385	COG2201	protein-glutamate methylesterase activity
AZC_RS03390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZC_RS03395	COG0840	transmembrane signaling receptor activity
AZC_RS03435	COG3729	General stress protein
AZC_RS03440	COG2855	membrane
AZC_RS03445	COG0583	DNA-binding transcription factor activity
AZC_RS03455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZC_RS03470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZC_RS03475	COG0243	molybdopterin cofactor binding
AZC_RS03480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZC_RS03485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_RS03490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_RS03500	COG1116	anion transmembrane transporter activity
AZC_RS03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS03510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS03525	COG0484	heat shock protein binding
AZC_RS03530	COG0443	Heat shock 70 kDa protein
AZC_RS03535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS03535	COG1116	anion transmembrane transporter activity
AZC_RS03540	COG2201	protein-glutamate methylesterase activity
AZC_RS03570	COG2267	carboxylic ester hydrolase activity
AZC_RS03585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZC_RS03595	COG3454	Phosphonate metabolism
AZC_RS03600	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_RS03615	COG0756	dUTP diphosphatase activity
AZC_RS03630	COG2205	protein histidine kinase activity
AZC_RS03635	COG3178	'Phosphotransferase
AZC_RS03640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZC_RS03645	COG2887	Belongs to the helicase family. UvrD subfamily
AZC_RS03650	COG1074	ATP-dependent DNA helicase activity
AZC_RS03660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_RS03675	COG0840	transmembrane signaling receptor activity
AZC_RS03685	COG0154	amidase activity
AZC_RS03690	COG0028	Belongs to the TPP enzyme family
AZC_RS03720	COG0765	amino acid transport
AZC_RS03725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZC_RS03730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS03745	COG3616	Alanine racemase, N-terminal domain
AZC_RS03780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_RS03795	COG2814	Major facilitator Superfamily
AZC_RS03805	COG0137	argininosuccinate synthase activity
AZC_RS03840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZC_RS03870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_RS03880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS03885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS03890	COG1116	anion transmembrane transporter activity
AZC_RS03895	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AZC_RS03910	COG1454	alcohol dehydrogenase
AZC_RS03915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_RS03920	COG2271	Major facilitator Superfamily
AZC_RS03925	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS03935	COG0405	Gamma-glutamyltransferase
AZC_RS03940	COG4608	Belongs to the ABC transporter superfamily
AZC_RS03945	COG0444	Belongs to the ABC transporter superfamily
AZC_RS03950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS03955	COG0601	transmembrane transport
AZC_RS03960	COG0747	negative chemotaxis
AZC_RS03985	COG1609	Transcriptional regulator
AZC_RS04000	COG4208	sulfate ABC transporter
AZC_RS04010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZC_RS04025	COG2351	hydroxyisourate hydrolase activity
AZC_RS04030	COG2233	PERMEase
AZC_RS04035	COG0583	DNA-binding transcription factor activity
AZC_RS04045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_RS04055	COG0101	tRNA pseudouridine synthase activity
AZC_RS04060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZC_RS04065	COG0242	peptide deformylase activity
AZC_RS04075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZC_RS04085	COG1024	Enoyl-CoA hydratase
AZC_RS04105	COG1252	NADH dehydrogenase
AZC_RS04125	COG4608	Belongs to the ABC transporter superfamily
AZC_RS04130	COG0444	Belongs to the ABC transporter superfamily
AZC_RS04135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS04150	COG0583	DNA-binding transcription factor activity
AZC_RS04155	COG1522	sequence-specific DNA binding
AZC_RS04160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZC_RS04165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS04170	COG0765	amino acid transport
AZC_RS04185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS04190	COG0840	transmembrane signaling receptor activity
AZC_RS04195	COG1304	FMN binding
AZC_RS04200	COG2186	Transcriptional regulator
AZC_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS04230	COG4974	Belongs to the 'phage' integrase family
AZC_RS04270	COG0305	Participates in initiation and elongation during chromosome replication
AZC_RS04390	COG3179	chitinase
AZC_RS04465	COG3549	Plasmid maintenance system killer
AZC_RS04495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZC_RS04515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZC_RS04525	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZC_RS04535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZC_RS04540	COG0081	regulation of translation
AZC_RS04545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZC_RS04550	COG0222	ribosome binding
AZC_RS04555	COG0085	RNA polymerase activity
AZC_RS04560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZC_RS04570	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AZC_RS04605	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AZC_RS04635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_RS04655	COG0142	geranyltranstransferase activity
AZC_RS04665	COG1742	UPF0060 membrane protein
AZC_RS04670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZC_RS04690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZC_RS04700	COG0412	Dienelactone hydrolase
AZC_RS04715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_RS04720	COG4208	sulfate ABC transporter
AZC_RS04725	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AZC_RS04730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZC_RS04735	COG0175	sulfate reduction
AZC_RS04745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_RS04755	COG0175	sulfate reduction
AZC_RS04765	COG0640	Transcriptional regulator
AZC_RS04785	COG1024	Enoyl-CoA hydratase
AZC_RS04800	COG4221	oxidoreductase activity
AZC_RS04810	COG0628	permease
AZC_RS04825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZC_RS04830	COG0302	gtp cyclohydrolase
AZC_RS04840	COG0671	phosphoesterase, PA-phosphatase related
AZC_RS04845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZC_RS04855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZC_RS04885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZC_RS04895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_RS04900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS04905	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_RS04915	COG0670	Belongs to the BI1 family
AZC_RS04945	COG0583	DNA-binding transcription factor activity
AZC_RS04950	COG2814	Major facilitator Superfamily
AZC_RS04975	COG2205	protein histidine kinase activity
AZC_RS04975	COG0784	Response regulator, receiver
AZC_RS04995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZC_RS05000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZC_RS05005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZC_RS05035	COG0531	amino acid
AZC_RS05040	COG1982	Orn Lys Arg decarboxylase major
AZC_RS05045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZC_RS05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_RS05070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZC_RS05085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZC_RS05085	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZC_RS05090	COG1414	Transcriptional regulator
AZC_RS05100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZC_RS05110	COG0604	alcohol dehydrogenase
AZC_RS05120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZC_RS05120	COG0493	'glutamate synthase
AZC_RS05130	COG0523	cobalamin synthesis protein
AZC_RS05135	COG1686	Belongs to the peptidase S11 family
AZC_RS05140	COG1132	(ABC) transporter
AZC_RS05150	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZC_RS05160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZC_RS05165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZC_RS05180	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_RS05185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZC_RS05195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZC_RS05200	COG0268	Binds directly to 16S ribosomal RNA
AZC_RS05210	COG0135	phosphoribosylanthranilate isomerase activity
AZC_RS05215	COG0133	tryptophan synthase activity
AZC_RS05225	COG0159	tryptophan synthase activity
AZC_RS05245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZC_RS05250	COG0285	dihydrofolate synthase activity
AZC_RS05275	COG0752	glycyl-tRNA synthetase alpha subunit
AZC_RS05290	COG0751	glycine-tRNA ligase activity
AZC_RS05300	COG3383	formate dehydrogenase (NAD+) activity
AZC_RS05315	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_RS05320	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_RS05325	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_RS05335	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZC_RS05340	COG2166	iron-sulfur cluster assembly
AZC_RS05345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZC_RS05350	COG0719	Fe-S assembly protein
AZC_RS05355	COG0396	ATPase activity
AZC_RS05360	COG0719	Fe-S assembly protein
AZC_RS05365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_RS05375	COG3604	Transcriptional regulator
AZC_RS05380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_RS05385	COG0450	alkyl hydroperoxide reductase
AZC_RS05400	COG3585	molybdate ion transport
AZC_RS05410	COG3639	organic phosphonate transmembrane transporter activity
AZC_RS05420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AZC_RS05425	COG0154	amidase activity
AZC_RS05445	COG0300	oxidoreductase activity
AZC_RS05450	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AZC_RS05455	COG0384	phenazine biosynthesis protein PhzF
AZC_RS05460	COG1902	pentaerythritol trinitrate reductase activity
AZC_RS05470	COG2095	MarC family integral membrane protein
AZC_RS05475	COG0431	NADPH-dependent FMN reductase
AZC_RS05485	COG0720	synthase
AZC_RS05490	COG0602	queuosine metabolic process
AZC_RS05495	COG0346	lactoylglutathione lyase activity
AZC_RS05500	COG0786	glutamate:sodium symporter activity
AZC_RS05520	COG1566	PFAM secretion protein HlyD family protein
AZC_RS05525	COG0840	transmembrane signaling receptor activity
AZC_RS05530	COG0583	DNA-binding transcription factor activity
AZC_RS05580	COG3152	Membrane
AZC_RS05585	COG2166	iron-sulfur cluster assembly
AZC_RS05595	COG2205	protein histidine kinase activity
AZC_RS05630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZC_RS05645	COG0477	Major facilitator Superfamily
AZC_RS05650	COG0523	cobalamin synthesis protein
AZC_RS05675	COG2814	Major facilitator Superfamily
AZC_RS05680	COG2188	Transcriptional regulator
AZC_RS05685	COG4695	Portal protein
AZC_RS05810	COG4235	cytochrome complex assembly
AZC_RS05815	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZC_RS05820	COG1138	Cytochrome C-type biogenesis protein
AZC_RS05825	COG3088	subunit of a heme lyase
AZC_RS05830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_RS05835	COG0745	RESPONSE REGULATOR receiver
AZC_RS05845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZC_RS05880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZC_RS05885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZC_RS05890	COG1522	sequence-specific DNA binding
AZC_RS05895	COG0492	ferredoxin-NADP+ reductase activity
AZC_RS05900	COG0583	DNA-binding transcription factor activity
AZC_RS05945	COG1921	L-seryl-tRNASec selenium transferase activity
AZC_RS05955	COG2864	formate dehydrogenase
AZC_RS05960	COG0437	4 iron, 4 sulfur cluster binding
AZC_RS05965	COG3383	formate dehydrogenase (NAD+) activity
AZC_RS05965	COG0243	molybdopterin cofactor binding
AZC_RS05970	COG3383	formate dehydrogenase (NAD+) activity
AZC_RS05970	COG0243	molybdopterin cofactor binding
AZC_RS05975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_RS05980	COG1305	Transglutaminase-like
AZC_RS05985	COG0709	Synthesizes selenophosphate from selenide and ATP
AZC_RS06005	COG0745	RESPONSE REGULATOR receiver
AZC_RS06020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_RS06020	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_RS06050	COG1902	pentaerythritol trinitrate reductase activity
AZC_RS06050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_RS06055	COG2181	nitrate reductase activity
AZC_RS06055	COG0247	lactate metabolic process
AZC_RS06070	COG0583	DNA-binding transcription factor activity
AZC_RS06085	COG2851	Citrate transporter
AZC_RS06095	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS06105	COG4176	ABC-type proline glycine betaine transport system permease component
AZC_RS06110	COG4175	Glycine betaine
AZC_RS06115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS06130	COG1522	sequence-specific DNA binding
AZC_RS06140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZC_RS06145	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS06165	COG0259	pyridoxamine-phosphate oxidase activity
AZC_RS06175	COG0484	heat shock protein binding
AZC_RS06180	COG0745	RESPONSE REGULATOR receiver
AZC_RS06205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_RS06210	COG0010	Belongs to the arginase family
AZC_RS06215	COG0387	Pfam Sodium calcium exchanger
AZC_RS06230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZC_RS06245	COG0420	3'-5' exonuclease activity
AZC_RS06260	COG0052	Belongs to the universal ribosomal protein uS2 family
AZC_RS06265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZC_RS06270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZC_RS06275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AZC_RS06280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AZC_RS06285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZC_RS06295	COG4251	negative regulation of phosphorylation
AZC_RS06295	COG5001	Diguanylate cyclase
AZC_RS06295	COG2203	Gaf domain
AZC_RS06295	COG3706	GGDEF domain
AZC_RS06320	COG2301	Belongs to the HpcH HpaI aldolase family
AZC_RS06330	COG0679	Auxin Efflux Carrier
AZC_RS06345	COG3842	ATPase activity
AZC_RS06350	COG1177	transmembrane transport
AZC_RS06355	COG1177	transmembrane transport
AZC_RS06375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS06390	COG0625	glutathione transferase activity
AZC_RS06400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS06405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZC_RS06440	COG1573	uracil-dna glycosylase
AZC_RS06450	COG1758	RNA polymerase activity
AZC_RS06455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_RS06460	COG2814	Major facilitator Superfamily
AZC_RS06480	COG0848	biopolymer transport protein
AZC_RS06490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZC_RS06495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZC_RS06500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_RS06500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_RS06510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZC_RS06520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AZC_RS06525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZC_RS06530	COG0640	Transcriptional regulator
AZC_RS06535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZC_RS06545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZC_RS06555	COG0431	NADPH-dependent FMN reductase
AZC_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS06575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_RS06585	COG1309	transcriptional regulator
AZC_RS06605	COG3436	PFAM IS66 Orf2 family protein
AZC_RS06610	COG2433	Pfam Transposase IS66
AZC_RS06615	COG1733	regulation of RNA biosynthetic process
AZC_RS06620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZC_RS06635	COG2207	Transcriptional regulator
AZC_RS06650	COG0583	DNA-binding transcription factor activity
AZC_RS06660	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS06670	COG3279	Response regulator of the LytR AlgR family
AZC_RS06675	COG3275	phosphorelay sensor kinase activity
AZC_RS06695	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AZC_RS06705	COG2610	gluconate transmembrane transporter activity
AZC_RS06725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZC_RS06730	COG3002	Belongs to the UPF0753 family
AZC_RS06740	COG0583	DNA-binding transcription factor activity
AZC_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS06765	COG0583	DNA-binding transcription factor activity
AZC_RS06780	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS06790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS06805	COG0583	DNA-binding transcription factor activity
AZC_RS06810	COG1301	dicarboxylic acid transport
AZC_RS06815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZC_RS06855	COG3712	iron ion homeostasis
AZC_RS06890	COG1999	signal sequence binding
AZC_RS06895	COG1858	cytochrome C peroxidase
AZC_RS06910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZC_RS06920	COG4191	Histidine kinase
AZC_RS06935	COG0025	NhaP-type Na H and K H
AZC_RS06940	COG2140	Oxalate decarboxylase
AZC_RS06955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZC_RS06955	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZC_RS06960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_RS06965	COG1294	oxidase, subunit
AZC_RS06970	COG1271	oxidase subunit
AZC_RS06975	COG0028	Belongs to the TPP enzyme family
AZC_RS06980	COG0243	molybdopterin cofactor binding
AZC_RS06985	COG1566	PFAM secretion protein HlyD family protein
AZC_RS07000	COG4191	Histidine kinase
AZC_RS07005	COG4566	intracellular signal transduction
AZC_RS07010	COG4566	intracellular signal transduction
AZC_RS07015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_RS07025	COG0367	asparagine synthase
AZC_RS07030	COG0121	glutamine amidotransferase
AZC_RS07090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_RS07100	COG4221	oxidoreductase activity
AZC_RS07105	COG0534	Mate efflux family protein
AZC_RS07140	COG2814	Major facilitator Superfamily
AZC_RS07145	COG0596	Alpha beta hydrolase
AZC_RS07155	COG0667	Aldo Keto reductase
AZC_RS07165	COG1275	C4-dicarboxylate transporter malic acid transport protein
AZC_RS07170	COG2010	Cytochrome c
AZC_RS07170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_RS07190	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AZC_RS07205	COG1278	Cold shock
AZC_RS07210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_RS07215	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AZC_RS07220	COG2080	2 iron, 2 sulfur cluster binding
AZC_RS07225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZC_RS07245	COG2186	Transcriptional regulator
AZC_RS07250	COG0129	dihydroxy-acid dehydratase activity
AZC_RS07265	COG1454	alcohol dehydrogenase
AZC_RS07270	COG0402	S-adenosylhomocysteine deaminase activity
AZC_RS07280	COG3485	protocatechuate 3,4-dioxygenase
AZC_RS07285	COG0277	FAD linked oxidase domain protein
AZC_RS07290	COG1129	ABC transporter
AZC_RS07295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZC_RS07300	COG4214	carbohydrate transport
AZC_RS07330	COG2223	nitrite transmembrane transporter activity
AZC_RS07335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AZC_RS07340	COG1140	nitrate reductase beta subunit
AZC_RS07345	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AZC_RS07350	COG2181	nitrate reductase activity
AZC_RS07355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZC_RS07365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZC_RS07370	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZC_RS07385	COG2132	Multicopper oxidase
AZC_RS07415	COG0683	leucine binding
AZC_RS07420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZC_RS07425	COG3485	protocatechuate 3,4-dioxygenase
AZC_RS07430	COG3485	protocatechuate 3,4-dioxygenase
AZC_RS07435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_RS07440	COG0583	DNA-binding transcription factor activity
AZC_RS07465	COG0765	amino acid transport
AZC_RS07470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS07475	COG1126	abc transporter atp-binding protein
AZC_RS07480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZC_RS07485	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AZC_RS07485	COG1082	Xylose isomerase domain protein TIM barrel
AZC_RS07495	COG2217	Heavy metal translocating P-type atpase
AZC_RS07500	COG0789	Transcriptional regulator
AZC_RS07520	COG3548	integral membrane protein
AZC_RS07530	COG1597	lipid kinase activity
AZC_RS07550	COG0328	RNA-DNA hybrid ribonuclease activity
AZC_RS07555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZC_RS07560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZC_RS07575	COG0589	response to stress
AZC_RS07580	COG0463	Glycosyl transferase, family 2
AZC_RS07595	COG4178	(ABC) transporter
AZC_RS07600	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS07630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_RS07635	COG2135	peptidase activity
AZC_RS07665	COG0477	Major facilitator Superfamily
AZC_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS07690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_RS07690	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_RS07700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS07705	COG4977	sequence-specific DNA binding
AZC_RS07720	COG0069	glutamate synthase activity
AZC_RS07725	COG2218	PFAM glutamate synthase alpha subunit domain protein
AZC_RS07730	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZC_RS07760	COG5265	(ABC) transporter
AZC_RS07770	COG0688	phosphatidylethanolamine metabolic process
AZC_RS07775	COG1183	phosphatidylcholine synthase activity
AZC_RS07790	COG0601	transmembrane transport
AZC_RS07795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS07800	COG4172	Belongs to the ABC transporter superfamily
AZC_RS07820	COG1802	Transcriptional regulator
AZC_RS07860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS07865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_RS07870	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZC_RS07890	COG0328	RNA-DNA hybrid ribonuclease activity
AZC_RS07905	COG1024	Enoyl-CoA hydratase
AZC_RS07915	COG0730	response to heat
AZC_RS07925	COG1703	isobutyryl-CoA mutase activity
AZC_RS07950	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AZC_RS07965	COG0113	porphobilinogen synthase activity
AZC_RS07970	COG1024	Enoyl-CoA hydratase
AZC_RS07995	COG0444	Belongs to the ABC transporter superfamily
AZC_RS08000	COG0154	amidase activity
AZC_RS08010	COG4608	Belongs to the ABC transporter superfamily
AZC_RS08015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS08025	COG4166	transmembrane transport
AZC_RS08055	COG1216	Glycosyl transferase, family 2
AZC_RS08105	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZC_RS08115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZC_RS08120	COG2205	protein histidine kinase activity
AZC_RS08190	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AZC_RS08195	COG0671	phosphoesterase, PA-phosphatase related
AZC_RS08200	COG0463	Glycosyl transferase, family 2
AZC_RS08210	COG0626	cystathionine gamma-synthase activity
AZC_RS08215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS08220	COG4597	amino acid ABC transporter
AZC_RS08225	COG0765	amino acid transport
AZC_RS08230	COG1126	abc transporter atp-binding protein
AZC_RS08240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZC_RS08250	COG0484	heat shock protein binding
AZC_RS08255	COG1686	Belongs to the peptidase S11 family
AZC_RS08265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZC_RS08280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZC_RS08300	COG0174	glutamine synthetase
AZC_RS08305	COG0347	Belongs to the P(II) protein family
AZC_RS08310	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZC_RS08310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZC_RS08320	COG0667	Aldo Keto reductase
AZC_RS08325	COG0583	DNA-binding transcription factor activity
AZC_RS08335	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZC_RS08340	COG0740	serine-type endopeptidase activity
AZC_RS08345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZC_RS08350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_RS08355	COG0776	regulation of translation
AZC_RS08365	COG2814	Major facilitator Superfamily
AZC_RS08370	COG0418	dihydroorotase activity
AZC_RS08395	COG3685	Protein conserved in bacteria
AZC_RS08415	COG1132	(ABC) transporter
AZC_RS08435	COG1120	ATPase activity
AZC_RS08440	COG4774	siderophore transport
AZC_RS08465	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS08470	COG4206	TonB-dependent receptor
AZC_RS08470	COG1629	transport
AZC_RS08475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZC_RS08495	COG2186	Transcriptional regulator
AZC_RS08500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_RS08540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_RS08550	COG2076	Multidrug Resistance protein
AZC_RS08580	COG2204	response regulator
AZC_RS08595	COG3956	TIGRFAM MazG family protein
AZC_RS08610	COG3768	UPF0283 membrane protein
AZC_RS08615	COG3106	COG3106 Predicted ATPase
AZC_RS08655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_RS08660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_RS08665	COG0649	NAD binding
AZC_RS08675	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZC_RS08680	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AZC_RS08695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZC_RS08700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_RS08710	COG0713	ATP synthesis coupled electron transport
AZC_RS08725	COG1007	ATP synthesis coupled electron transport
AZC_RS08740	COG0346	lactoylglutathione lyase activity
AZC_RS08750	COG0442	prolyl-tRNA aminoacylation
AZC_RS08760	COG1136	(ABC) transporter
AZC_RS08785	COG0052	Belongs to the universal ribosomal protein uS2 family
AZC_RS08790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZC_RS08795	COG0528	UMP kinase activity
AZC_RS08800	COG0233	cytoplasmic translational termination
AZC_RS08805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZC_RS08820	COG0750	zinc metalloprotease
AZC_RS08825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZC_RS08830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_RS08835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_RS08840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_RS08845	COG3494	Protein of unknown function (DUF1009)
AZC_RS08850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_RS08855	COG0583	DNA-binding transcription factor activity
AZC_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS08870	COG0372	Belongs to the citrate synthase family
AZC_RS08875	COG0746	molybdenum cofactor guanylyltransferase activity
AZC_RS08910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZC_RS08915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZC_RS08940	COG2832	Protein of unknown function (DUF454)
AZC_RS08960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZC_RS08980	COG1472	Belongs to the glycosyl hydrolase 3 family
AZC_RS08985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZC_RS08990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZC_RS08995	COG3842	ATPase activity
AZC_RS09000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZC_RS09005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZC_RS09010	COG0805	protein transport
AZC_RS09015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZC_RS09025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZC_RS09035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_RS09035	COG0022	dehydrogenase e1 component
AZC_RS09040	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_RS09050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZC_RS09055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZC_RS09060	COG2867	negative regulation of translational initiation
AZC_RS09065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZC_RS09070	COG1253	flavin adenine dinucleotide binding
AZC_RS09090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_RS09110	COG2239	Acts as a magnesium transporter
AZC_RS09130	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS09150	COG0829	nickel cation binding
AZC_RS09155	COG0832	Belongs to the urease beta subunit family
AZC_RS09155	COG0831	urea catabolic process
AZC_RS09165	COG0804	urea catabolic process
AZC_RS09170	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZC_RS09175	COG0830	nickel cation binding
AZC_RS09180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AZC_RS09205	COG4770	biotin carboxylase activity
AZC_RS09210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZC_RS09215	COG3800	Transcriptional regulator
AZC_RS09215	COG1396	sequence-specific DNA binding
AZC_RS09230	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AZC_RS09230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZC_RS09240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZC_RS09245	COG3045	CreA protein
AZC_RS09255	COG0215	cysteine-tRNA ligase activity
AZC_RS09265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZC_RS09295	COG0288	reversible hydration of carbon dioxide
AZC_RS09330	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS09335	COG3842	ATPase activity
AZC_RS09345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZC_RS09370	COG1764	response to oxidative stress
AZC_RS09375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AZC_RS09380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_RS09390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZC_RS09395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZC_RS09410	COG0537	adenosine 5'-monophosphoramidase activity
AZC_RS09425	COG2308	Evidence 4 Homologs of previously reported genes of
AZC_RS09430	COG1546	Belongs to the CinA family
AZC_RS09430	COG1058	Belongs to the CinA family
AZC_RS09440	COG3909	cytochrome
AZC_RS09455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_RS09465	COG0351	phosphomethylpyrimidine kinase
AZC_RS09470	COG1396	sequence-specific DNA binding
AZC_RS09485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZC_RS09495	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZC_RS09500	COG1088	dTDP-glucose 4,6-dehydratase activity
AZC_RS09520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS09525	COG0765	amino acid transport
AZC_RS09530	COG0765	amino acid transport
AZC_RS09535	COG1126	abc transporter atp-binding protein
AZC_RS09540	COG2267	carboxylic ester hydrolase activity
AZC_RS09545	COG2301	Belongs to the HpcH HpaI aldolase family
AZC_RS09555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_RS09560	COG0583	DNA-binding transcription factor activity
AZC_RS09565	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZC_RS09575	COG0436	Aminotransferase
AZC_RS09600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZC_RS09610	COG0784	Response regulator, receiver
AZC_RS09615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZC_RS09635	COG0557	exoribonuclease II activity
AZC_RS09640	COG0477	Major facilitator Superfamily
AZC_RS09645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZC_RS09665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_RS09670	COG0538	isocitrate dehydrogenase activity
AZC_RS09695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS09700	COG0601	transmembrane transport
AZC_RS09705	COG0747	negative chemotaxis
AZC_RS09715	COG0583	DNA-binding transcription factor activity
AZC_RS09725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS09730	COG2030	dehydratase
AZC_RS09740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZC_RS09745	COG1802	Transcriptional regulator
AZC_RS09760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AZC_RS09765	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS09810	COG2084	Dehydrogenase
AZC_RS09820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZC_RS09825	COG0583	DNA-binding transcription factor activity
AZC_RS09830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS09840	COG3610	response to peptide
AZC_RS09845	COG0579	oxidoreductase
AZC_RS09855	COG0114	fumarate hydratase activity
AZC_RS09870	COG2271	Major facilitator Superfamily
AZC_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS09885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_RS09885	COG0596	Alpha beta hydrolase
AZC_RS09890	COG0022	dehydrogenase e1 component
AZC_RS09895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZC_RS09900	COG3199	ATP-NAD kinase
AZC_RS09905	COG3284	Transcriptional regulator
AZC_RS09915	COG4771	TonB-dependent receptor
AZC_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS09970	COG1126	abc transporter atp-binding protein
AZC_RS09975	COG0765	amino acid transport
AZC_RS09980	COG0765	amino acid transport
AZC_RS09990	COG0583	DNA-binding transcription factor activity
AZC_RS10015	COG2963	transposase activity
AZC_RS10035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZC_RS10040	COG1278	Cold shock
AZC_RS10070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS10080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS10100	COG0477	Major facilitator Superfamily
AZC_RS10105	COG0583	DNA-binding transcription factor activity
AZC_RS10115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS10145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10150	COG0601	transmembrane transport
AZC_RS10155	COG0747	negative chemotaxis
AZC_RS10160	COG2072	flavoprotein involved in K transport
AZC_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS10200	COG2351	hydroxyisourate hydrolase activity
AZC_RS10210	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS10215	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_RS10220	COG3842	ATPase activity
AZC_RS10225	COG0154	amidase activity
AZC_RS10230	COG2186	Transcriptional regulator
AZC_RS10235	COG1454	alcohol dehydrogenase
AZC_RS10245	COG1116	anion transmembrane transporter activity
AZC_RS10250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS10260	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS10265	COG4957	zinc ion binding
AZC_RS10270	COG4608	Belongs to the ABC transporter superfamily
AZC_RS10275	COG0444	Belongs to the ABC transporter superfamily
AZC_RS10280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10285	COG0601	transmembrane transport
AZC_RS10290	COG0747	negative chemotaxis
AZC_RS10295	COG1473	amidohydrolase
AZC_RS10305	COG1177	transmembrane transport
AZC_RS10310	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS10315	COG3842	ATPase activity
AZC_RS10320	COG1840	ABC-type Fe3 transport system, periplasmic component
AZC_RS10335	COG2223	nitrite transmembrane transporter activity
AZC_RS10355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_RS10370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZC_RS10375	COG0736	holo-[acyl-carrier-protein] synthase activity
AZC_RS10380	COG0681	Belongs to the peptidase S26 family
AZC_RS10385	COG0571	ribonuclease III activity
AZC_RS10390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZC_RS10395	COG1381	Involved in DNA repair and RecF pathway recombination
AZC_RS10405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZC_RS10415	COG0235	Class ii aldolase
AZC_RS10420	COG2423	ornithine cyclodeaminase activity
AZC_RS10425	COG4608	Belongs to the ABC transporter superfamily
AZC_RS10430	COG0444	Belongs to the ABC transporter superfamily
AZC_RS10435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10440	COG0601	transmembrane transport
AZC_RS10445	COG0747	negative chemotaxis
AZC_RS10450	COG3964	amidohydrolase
AZC_RS10470	COG0154	amidase activity
AZC_RS10475	COG2271	Major facilitator Superfamily
AZC_RS10505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10510	COG0601	transmembrane transport
AZC_RS10515	COG0747	negative chemotaxis
AZC_RS10540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS10545	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS10550	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS10580	COG0154	amidase activity
AZC_RS10595	COG0747	negative chemotaxis
AZC_RS10600	COG0601	transmembrane transport
AZC_RS10605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10620	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS10635	COG2514	catechol 2,3-dioxygenase activity
AZC_RS10640	COG0435	Glutathione S-transferase
AZC_RS10650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS10660	COG1116	anion transmembrane transporter activity
AZC_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS10680	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS10695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZC_RS10700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS10705	COG1522	sequence-specific DNA binding
AZC_RS10710	COG1280	lysine exporter protein (LysE YggA)
AZC_RS10715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS10720	COG1126	abc transporter atp-binding protein
AZC_RS10725	COG0765	amino acid transport
AZC_RS10735	COG1396	sequence-specific DNA binding
AZC_RS10745	COG1473	amidohydrolase
AZC_RS10760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS10765	COG0601	transmembrane transport
AZC_RS10770	COG0747	negative chemotaxis
AZC_RS10800	COG0640	Transcriptional regulator
AZC_RS10805	COG0477	Major facilitator Superfamily
AZC_RS10850	COG0671	phosphoesterase, PA-phosphatase related
AZC_RS10855	COG0477	Major facilitator Superfamily
AZC_RS10860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZC_RS10865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZC_RS10870	COG1845	cytochrome c oxidase, subunit III
AZC_RS10875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZC_RS10890	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZC_RS10895	COG1053	succinate dehydrogenase
AZC_RS10900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZC_RS10905	COG0066	3-isopropylmalate dehydratase activity
AZC_RS10910	COG2188	Transcriptional regulator
AZC_RS10970	COG1335	isochorismatase
AZC_RS11030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZC_RS11085	COG4373	Mu-like prophage FluMu protein gp28
AZC_RS11115	COG4397	Mu-like prophage major head subunit gpT
AZC_RS11250	COG1686	Belongs to the peptidase S11 family
AZC_RS11255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZC_RS11260	COG0470	DNA polymerase III
AZC_RS11270	COG3181	Tripartite tricarboxylate transporter family receptor
AZC_RS11275	COG1268	BioY protein
AZC_RS11280	COG0084	hydrolase, TatD family'
AZC_RS11295	COG0583	DNA-binding transcription factor activity
AZC_RS11305	COG1346	cytolysis
AZC_RS11310	COG1612	heme a metabolic process
AZC_RS11325	COG1024	Enoyl-CoA hydratase
AZC_RS11335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZC_RS11340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZC_RS11345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZC_RS11360	COG0667	Aldo Keto reductase
AZC_RS11380	COG1473	amidohydrolase
AZC_RS11390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZC_RS11400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZC_RS11405	COG0303	'Molybdopterin
AZC_RS11410	COG0315	cyclic pyranopterin monophosphate synthase activity
AZC_RS11420	COG0134	indole-3-glycerol-phosphate synthase activity
AZC_RS11425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZC_RS11435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZC_RS11455	COG4948	Mandelate Racemase Muconate Lactonizing
AZC_RS11460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZC_RS11465	COG1127	ABC transporter
AZC_RS11490	COG0633	Ferredoxin
AZC_RS11495	COG0463	Glycosyl transferase, family 2
AZC_RS11505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZC_RS11515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZC_RS11520	COG1285	pathogenesis
AZC_RS11535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZC_RS11540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZC_RS11545	COG0047	phosphoribosylformylglycinamidine synthase activity
AZC_RS11550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZC_RS11580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZC_RS11595	COG0612	Peptidase, M16
AZC_RS11600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_RS11610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_RS11620	COG1840	ABC-type Fe3 transport system, periplasmic component
AZC_RS11630	COG2205	protein histidine kinase activity
AZC_RS11650	COG0859	PFAM glycosyl transferase family 9
AZC_RS11655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_RS11660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZC_RS11660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZC_RS11665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_RS11680	COG1492	cobalamin metabolic process
AZC_RS11690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZC_RS11695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_RS11705	COG1238	metal cluster binding
AZC_RS11710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZC_RS11710	COG0321	lipoyl(octanoyl) transferase activity
AZC_RS11720	COG1280	lysine exporter protein (LysE YggA)
AZC_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS11740	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS11745	COG4948	Mandelate Racemase Muconate Lactonizing
AZC_RS11750	COG2271	Major facilitator Superfamily
AZC_RS11770	COG1116	anion transmembrane transporter activity
AZC_RS11775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS11780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS11795	COG4566	intracellular signal transduction
AZC_RS11800	COG4566	intracellular signal transduction
AZC_RS11820	COG3685	Protein conserved in bacteria
AZC_RS11830	COG3655	Transcriptional regulator
AZC_RS11860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AZC_RS11870	COG0776	regulation of translation
AZC_RS11875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZC_RS11880	COG0416	fatty acid biosynthetic process
AZC_RS11905	COG0438	transferase activity, transferring glycosyl groups
AZC_RS11915	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS11920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AZC_RS11935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZC_RS11940	COG0343	queuine tRNA-ribosyltransferase activity
AZC_RS11945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZC_RS11950	COG3932	Exopolysaccharide synthesis, ExoD
AZC_RS11955	COG5425	PFAM Usg family protein
AZC_RS11960	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZC_RS11965	COG0459	protein refolding
AZC_RS11985	COG1254	Belongs to the acylphosphatase family
AZC_RS12020	COG0563	adenylate kinase activity
AZC_RS12035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZC_RS12040	COG1280	lysine exporter protein (LysE YggA)
AZC_RS12055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS12065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AZC_RS12070	COG2814	Major facilitator Superfamily
AZC_RS12090	COG1414	Transcriptional regulator
AZC_RS12095	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_RS12115	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS12135	COG1309	transcriptional regulator
AZC_RS12150	COG0673	inositol 2-dehydrogenase activity
AZC_RS12160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZC_RS12165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS12170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS12190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZC_RS12200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZC_RS12205	COG0546	phosphoglycolate phosphatase activity
AZC_RS12215	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_RS12220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS12225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS12240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZC_RS12245	COG0513	Belongs to the DEAD box helicase family
AZC_RS12250	COG0586	Pfam SNARE associated Golgi protein
AZC_RS12260	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZC_RS12265	COG4149	molybdate abc transporter
AZC_RS12270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AZC_RS12285	COG0716	FMN binding
AZC_RS12290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZC_RS12300	COG0028	Belongs to the TPP enzyme family
AZC_RS12310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZC_RS12315	COG0483	inositol monophosphate 1-phosphatase activity
AZC_RS12330	COG1519	Transferase
AZC_RS12335	COG1663	tetraacyldisaccharide 4'-kinase activity
AZC_RS12345	COG1570	exodeoxyribonuclease VII activity
AZC_RS12350	COG0151	Belongs to the GarS family
AZC_RS12355	COG0596	Alpha beta hydrolase
AZC_RS12365	COG0590	tRNA wobble adenosine to inosine editing
AZC_RS12370	COG1187	pseudouridine synthase activity
AZC_RS12375	COG0742	ribosomal rna small subunit methyltransferase
AZC_RS12380	COG0668	transmembrane transport
AZC_RS12385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZC_RS12395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZC_RS12400	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AZC_RS12410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZC_RS12415	COG2321	neutral zinc metallopeptidase
AZC_RS12420	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZC_RS12430	COG1960	acyl-CoA dehydrogenase activity
AZC_RS12435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_RS12440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_RS12445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_RS12450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_RS12460	COG1063	alcohol dehydrogenase
AZC_RS12465	COG1560	Kdo2-lipid A biosynthetic process
AZC_RS12480	COG3706	GGDEF domain
AZC_RS12490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZC_RS12500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS12510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_RS12530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZC_RS12545	COG0129	dihydroxy-acid dehydratase activity
AZC_RS12550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_RS12585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_RS12590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AZC_RS12610	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AZC_RS12620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZC_RS12635	COG2267	carboxylic ester hydrolase activity
AZC_RS12640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZC_RS12645	COG0300	oxidoreductase activity
AZC_RS12665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS12670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS12680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS12690	COG3795	YCII-related domain
AZC_RS12695	COG4941	Belongs to the sigma-70 factor family
AZC_RS12700	COG1802	Transcriptional regulator
AZC_RS12715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_RS12730	COG3842	ATPase activity
AZC_RS12735	COG4208	sulfate ABC transporter
AZC_RS12740	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS12755	COG0583	DNA-binding transcription factor activity
AZC_RS12760	COG0840	transmembrane signaling receptor activity
AZC_RS12760	COG0840	transmembrane signaling receptor activity
AZC_RS12765	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_RS12765	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AZC_RS12780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS12795	COG1846	Transcriptional regulator
AZC_RS12800	COG0277	FAD linked oxidase domain protein
AZC_RS12815	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS12820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS12860	COG0765	amino acid transport
AZC_RS12865	COG0765	amino acid transport
AZC_RS12875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_RS12885	COG0583	DNA-binding transcription factor activity
AZC_RS12895	COG1335	isochorismatase
AZC_RS12900	COG0251	oxidation-reduction process
AZC_RS12905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS12910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS12915	COG1116	anion transmembrane transporter activity
AZC_RS12920	COG0583	DNA-binding transcription factor activity
AZC_RS12930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS12935	COG1024	Enoyl-CoA hydratase
AZC_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS12970	COG5001	Diguanylate cyclase
AZC_RS12970	COG2203	Gaf domain
AZC_RS12970	COG4251	negative regulation of phosphorylation
AZC_RS12970	COG3706	GGDEF domain
AZC_RS12975	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AZC_RS12985	COG2610	gluconate transmembrane transporter activity
AZC_RS12990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZC_RS12995	COG2203	Gaf domain
AZC_RS12995	COG2199	diguanylate cyclase activity
AZC_RS13000	COG0187	DNA topoisomerase II activity
AZC_RS13010	COG0513	Belongs to the DEAD box helicase family
AZC_RS13035	COG0546	phosphoglycolate phosphatase activity
AZC_RS13045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_RS13060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZC_RS13070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZC_RS13075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_RS13080	COG0203	ribosomal protein L17
AZC_RS13085	COG0202	RNA polymerase activity
AZC_RS13090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZC_RS13095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZC_RS13100	COG0563	adenylate kinase activity
AZC_RS13110	COG0200	Binds to the 23S rRNA
AZC_RS13115	COG1841	ribosomal large subunit assembly
AZC_RS13120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZC_RS13125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZC_RS13130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZC_RS13135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZC_RS13140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZC_RS13145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZC_RS13150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZC_RS13155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZC_RS13160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZC_RS13165	COG0255	Belongs to the universal ribosomal protein uL29 family
AZC_RS13170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZC_RS13175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZC_RS13180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZC_RS13185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZC_RS13190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZC_RS13195	COG0089	rRNA binding
AZC_RS13200	COG0088	Forms part of the polypeptide exit tunnel
AZC_RS13205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZC_RS13210	COG0051	transcription antitermination factor activity, RNA binding
AZC_RS13215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZC_RS13220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZC_RS13225	COG0049	tRNA binding
AZC_RS13230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZC_RS13240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AZC_RS13245	COG1704	LemA family
AZC_RS13250	COG2827	Endonuclease containing a URI domain
AZC_RS13265	COG0114	fumarate hydratase activity
AZC_RS13285	COG0330	HflC and HflK could
AZC_RS13300	COG0840	transmembrane signaling receptor activity
AZC_RS13305	COG0560	Phosphoserine phosphatase
AZC_RS13310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZC_RS13315	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZC_RS13320	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AZC_RS13325	COG0154	amidase activity
AZC_RS13330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS13340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS13350	COG0631	protein serine/threonine phosphatase activity
AZC_RS13470	COG0500	methyltransferase
AZC_RS13490	COG0251	oxidation-reduction process
AZC_RS13495	COG2084	Dehydrogenase
AZC_RS13500	COG1609	Transcriptional regulator
AZC_RS13510	COG1063	alcohol dehydrogenase
AZC_RS13515	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS13520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS13530	COG0765	amino acid transport
AZC_RS13540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_RS13545	COG2706	6-phosphogluconolactonase activity
AZC_RS13560	COG0154	amidase activity
AZC_RS13570	COG0154	amidase activity
AZC_RS13580	COG4166	transmembrane transport
AZC_RS13585	COG0601	transmembrane transport
AZC_RS13590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS13595	COG4608	Belongs to the ABC transporter superfamily
AZC_RS13600	COG0444	Belongs to the ABC transporter superfamily
AZC_RS13610	COG0154	amidase activity
AZC_RS13620	COG0154	amidase activity
AZC_RS13625	COG0154	amidase activity
AZC_RS13640	COG2721	sulfolactate sulfo-lyase activity
AZC_RS13645	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS13650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS13655	COG0583	DNA-binding transcription factor activity
AZC_RS13660	COG2271	Major facilitator Superfamily
AZC_RS13665	COG0628	permease
AZC_RS13670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZC_RS13680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS13720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS13730	COG4608	Belongs to the ABC transporter superfamily
AZC_RS13745	COG1309	transcriptional regulator
AZC_RS13760	COG0601	transmembrane transport
AZC_RS13765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS13780	COG0667	Aldo Keto reductase
AZC_RS13785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS13805	COG0657	acetylesterase activity
AZC_RS13815	COG0583	DNA-binding transcription factor activity
AZC_RS13820	COG2828	Protein conserved in bacteria
AZC_RS13825	COG1301	dicarboxylic acid transport
AZC_RS13840	COG1278	Cold shock
AZC_RS13845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZC_RS13855	COG1126	abc transporter atp-binding protein
AZC_RS13860	COG0765	amino acid transport
AZC_RS13865	COG0765	amino acid transport
AZC_RS13870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS13900	COG1850	ribulose-bisphosphate carboxylase activity
AZC_RS13910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_RS13915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS13925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_RS13930	COG0154	amidase activity
AZC_RS13935	COG4608	Belongs to the ABC transporter superfamily
AZC_RS13945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS13950	COG0601	transmembrane transport
AZC_RS13955	COG0747	negative chemotaxis
AZC_RS13960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_RS14020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZC_RS14025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZC_RS14035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS14050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS14055	COG3706	GGDEF domain
AZC_RS14075	COG1414	Transcriptional regulator
AZC_RS14080	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS14085	COG1177	transmembrane transport
AZC_RS14095	COG3842	ATPase activity
AZC_RS14120	COG0402	S-adenosylhomocysteine deaminase activity
AZC_RS14125	COG0583	DNA-binding transcription factor activity
AZC_RS14135	COG0765	amino acid transport
AZC_RS14140	COG1126	abc transporter atp-binding protein
AZC_RS14155	COG0747	negative chemotaxis
AZC_RS14170	COG4977	sequence-specific DNA binding
AZC_RS14180	COG3046	protein related to deoxyribodipyrimidine photolyase
AZC_RS14185	COG0672	)-iron permease
AZC_RS14195	COG2132	Multicopper oxidase
AZC_RS14215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZC_RS14260	COG5265	(ABC) transporter
AZC_RS14265	COG0438	transferase activity, transferring glycosyl groups
AZC_RS14290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZC_RS14290	COG0574	Belongs to the PEP-utilizing enzyme family
AZC_RS14315	COG1312	Catalyzes the dehydration of D-mannonate
AZC_RS14320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_RS14335	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS14340	COG1522	sequence-specific DNA binding
AZC_RS14350	COG3395	kinase activity
AZC_RS14355	COG3622	Belongs to the hyi family
AZC_RS14360	COG2084	Dehydrogenase
AZC_RS14365	COG1609	Transcriptional regulator
AZC_RS14370	COG0235	Class ii aldolase
AZC_RS14380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AZC_RS14415	COG0477	Major facilitator Superfamily
AZC_RS14420	COG1396	sequence-specific DNA binding
AZC_RS14425	COG1846	Transcriptional regulator
AZC_RS14475	COG2080	2 iron, 2 sulfur cluster binding
AZC_RS14480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_RS14480	COG2010	Cytochrome c
AZC_RS14485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZC_RS14505	COG0018	arginyl-trna synthetase
AZC_RS14510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AZC_RS14515	COG0316	Belongs to the HesB IscA family
AZC_RS14530	COG1696	Membrane protein involved in D-alanine export
AZC_RS14540	COG1744	ABC transporter substrate-binding protein PnrA-like
AZC_RS14550	COG0525	valine-tRNA ligase activity
AZC_RS14565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZC_RS14580	COG1132	(ABC) transporter
AZC_RS14605	COG0415	Belongs to the DNA photolyase family
AZC_RS14610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZC_RS14615	COG2897	thiosulfate sulfurtransferase activity
AZC_RS14620	COG0840	transmembrane signaling receptor activity
AZC_RS14650	COG1960	acyl-CoA dehydrogenase activity
AZC_RS14655	COG5001	Diguanylate cyclase
AZC_RS14660	COG2239	Acts as a magnesium transporter
AZC_RS14685	COG0321	lipoyl(octanoyl) transferase activity
AZC_RS14690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZC_RS14695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZC_RS14700	COG0514	ATP-dependent DNA helicase (RecQ)
AZC_RS14705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZC_RS14710	COG0154	amidase activity
AZC_RS14725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZC_RS14730	COG0758	DNA mediated transformation
AZC_RS14735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZC_RS14740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZC_RS14745	COG0540	Belongs to the ATCase OTCase family
AZC_RS14760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZC_RS14765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZC_RS14780	COG2271	Major facilitator Superfamily
AZC_RS14795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AZC_RS14810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_RS14815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS14825	COG1024	Enoyl-CoA hydratase
AZC_RS14860	COG1024	Enoyl-CoA hydratase
AZC_RS14860	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_RS14865	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS14870	COG0183	Belongs to the thiolase family
AZC_RS14875	COG1960	acyl-CoA dehydrogenase activity
AZC_RS14880	COG1960	acyl-CoA dehydrogenase activity
AZC_RS14890	COG0477	Major facilitator Superfamily
AZC_RS14900	COG3246	L-lysine catabolic process to acetate
AZC_RS14905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_RS14910	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_RS14915	COG1414	Transcriptional regulator
AZC_RS14925	COG0629	single-stranded DNA binding
AZC_RS14930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZC_RS14935	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AZC_RS14950	COG3737	Protein of unknown function (DUF498/DUF598)
AZC_RS14960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZC_RS14965	COG1862	Preprotein translocase
AZC_RS14970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZC_RS14990	COG0656	L-ascorbic acid biosynthetic process
AZC_RS14995	COG3979	chitinase
AZC_RS15010	COG1012	belongs to the aldehyde dehydrogenase family
AZC_RS15020	COG0583	DNA-binding transcription factor activity
AZC_RS15025	COG4608	Belongs to the ABC transporter superfamily
AZC_RS15035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS15060	COG0501	Belongs to the peptidase M48B family
AZC_RS15095	COG4647	ligase activity
AZC_RS15100	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AZC_RS15105	COG0145	ligase activity
AZC_RS15130	COG0625	glutathione transferase activity
AZC_RS15135	COG1509	lysine 2,3-aminomutase activity
AZC_RS15145	COG3608	succinylglutamate desuccinylase aspartoacylase
AZC_RS15145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZC_RS15155	COG2814	Major facilitator Superfamily
AZC_RS15170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_RS15230	COG0683	leucine binding
AZC_RS15240	COG0785	Cytochrome C biogenesis protein
AZC_RS15245	COG3191	aminopeptidase activity
AZC_RS15255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS15260	COG3346	SURF1 family
AZC_RS15275	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AZC_RS15285	COG0109	protoheme IX farnesyltransferase activity
AZC_RS15290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZC_RS15295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZC_RS15325	COG0583	DNA-binding transcription factor activity
AZC_RS15335	COG0628	permease
AZC_RS15340	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS15355	COG0183	Belongs to the thiolase family
AZC_RS15360	COG1024	Enoyl-CoA hydratase
AZC_RS15360	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_RS15365	COG1960	acyl-CoA dehydrogenase activity
AZC_RS15380	COG1764	response to oxidative stress
AZC_RS15400	COG0840	transmembrane signaling receptor activity
AZC_RS15410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_RS15420	COG1785	Belongs to the alkaline phosphatase family
AZC_RS15440	COG0667	Aldo Keto reductase
AZC_RS15445	COG1446	asparaginase
AZC_RS15450	COG2362	D-Aminopeptidase
AZC_RS15460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS15470	COG0747	negative chemotaxis
AZC_RS15475	COG4172	Belongs to the ABC transporter superfamily
AZC_RS15490	COG1228	amidohydrolase
AZC_RS15535	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZC_RS15555	COG2204	response regulator
AZC_RS15560	COG4191	Histidine kinase
AZC_RS15565	COG1301	dicarboxylic acid transport
AZC_RS15570	COG0861	Integral membrane protein TerC family
AZC_RS15580	COG0583	DNA-binding transcription factor activity
AZC_RS15585	COG1982	Orn Lys Arg decarboxylase major
AZC_RS15600	COG0528	UMP kinase activity
AZC_RS15605	COG0528	UMP kinase activity
AZC_RS15615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_RS15625	COG2226	methyltransferase
AZC_RS15630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS15635	COG3179	chitinase
AZC_RS15650	COG2059	Chromate
AZC_RS15670	COG0387	Pfam Sodium calcium exchanger
AZC_RS15675	COG0165	Argininosuccinate lyase
AZC_RS15680	COG1414	Transcriptional regulator
AZC_RS15740	COG1760	l-serine dehydratase
AZC_RS15745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZC_RS15755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZC_RS15785	COG0433	COG0433 Predicted ATPase
AZC_RS15795	COG0148	phosphopyruvate hydratase activity
AZC_RS15800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZC_RS15810	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZC_RS15815	COG2076	Multidrug Resistance protein
AZC_RS15825	COG0504	CTP synthase activity
AZC_RS15835	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZC_RS15840	COG0436	Aminotransferase
AZC_RS15855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZC_RS15860	COG0511	ligase activity, forming carbon-carbon bonds
AZC_RS15870	COG1116	anion transmembrane transporter activity
AZC_RS15885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZC_RS15890	COG1923	regulation of RNA biosynthetic process
AZC_RS15900	COG0569	domain protein
AZC_RS15905	COG2204	response regulator
AZC_RS15910	COG5000	phosphorelay sensor kinase activity
AZC_RS15915	COG2203	Gaf domain
AZC_RS15915	COG2199	diguanylate cyclase activity
AZC_RS15915	COG2200	EAL domain
AZC_RS15920	COG2204	response regulator
AZC_RS15935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZC_RS15935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZC_RS15940	COG1058	Belongs to the CinA family
AZC_RS15940	COG1546	Belongs to the CinA family
AZC_RS15945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZC_RS15960	COG4566	intracellular signal transduction
AZC_RS15975	COG0477	Major facilitator Superfamily
AZC_RS15980	COG4191	Histidine kinase
AZC_RS16000	COG1335	isochorismatase
AZC_RS16005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZC_RS16005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZC_RS16015	COG3781	membrane
AZC_RS16025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZC_RS16030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZC_RS16050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZC_RS16055	COG3754	Rhamnan synthesis protein F
AZC_RS16075	COG1722	exodeoxyribonuclease VII activity
AZC_RS16085	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZC_RS16095	COG0308	aminopeptidase N
AZC_RS16105	COG0583	DNA-binding transcription factor activity
AZC_RS16110	COG2205	protein histidine kinase activity
AZC_RS16110	COG2202	Pas domain
AZC_RS16125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AZC_RS16125	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AZC_RS16135	COG0556	nucleotide-excision repair
AZC_RS16155	COG0625	glutathione transferase activity
AZC_RS16160	COG0436	Aminotransferase
AZC_RS16180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_RS16195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZC_RS16220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZC_RS16225	COG0424	maF-like protein
AZC_RS16230	COG2267	carboxylic ester hydrolase activity
AZC_RS16240	COG5328	Belongs to the UPF0262 family
AZC_RS16245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZC_RS16255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZC_RS16275	COG0840	transmembrane signaling receptor activity
AZC_RS16285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS16295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_RS16300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_RS16305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS16320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS16330	COG3258	Cytochrome c
AZC_RS16335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_RS16340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS16345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_RS16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS16365	COG1116	anion transmembrane transporter activity
AZC_RS16370	COG1464	Belongs to the NlpA lipoprotein family
AZC_RS16380	COG0778	Nitroreductase
AZC_RS16395	COG1959	2 iron, 2 sulfur cluster binding
AZC_RS16400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS16405	COG1032	radical SAM domain protein
AZC_RS16435	COG1960	acyl-CoA dehydrogenase activity
AZC_RS16440	COG1024	Enoyl-CoA hydratase
AZC_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS16460	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS16470	COG1129	ABC transporter
AZC_RS16490	COG1414	Transcriptional regulator
AZC_RS16495	COG1744	ABC transporter substrate-binding protein PnrA-like
AZC_RS16500	COG3845	ABC transporter
AZC_RS16510	COG1079	Belongs to the binding-protein-dependent transport system permease family
AZC_RS16520	COG0154	amidase activity
AZC_RS16530	COG2274	protein secretion by the type I secretion system
AZC_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS16560	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_RS16565	COG3829	transcription factor binding
AZC_RS16575	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZC_RS16585	COG1215	transferase activity, transferring glycosyl groups
AZC_RS16620	COG2814	Major facilitator Superfamily
AZC_RS16630	COG3300	MHYT domain
AZC_RS16630	COG5001	Diguanylate cyclase
AZC_RS16655	COG0457	Tetratricopeptide repeat
AZC_RS16675	COG1120	ATPase activity
AZC_RS16690	COG4774	siderophore transport
AZC_RS16695	COG2311	Membrane
AZC_RS16705	COG0626	cystathionine gamma-synthase activity
AZC_RS16735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZC_RS16740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_RS16745	COG2819	hydrolase of the alpha beta superfamily
AZC_RS16775	COG3093	addiction module antidote protein HigA
AZC_RS16795	COG0419	ATPase involved in DNA repair
AZC_RS16805	COG2963	transposase activity
AZC_RS16815	COG1674	ftsk spoiiie
AZC_RS16855	COG1063	alcohol dehydrogenase
AZC_RS16870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_RS16875	COG2080	2 iron, 2 sulfur cluster binding
AZC_RS16890	COG2721	sulfolactate sulfo-lyase activity
AZC_RS16895	COG1063	alcohol dehydrogenase
AZC_RS16900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS16905	COG1126	abc transporter atp-binding protein
AZC_RS16910	COG0765	amino acid transport
AZC_RS16920	COG0246	Mannitol dehydrogenase
AZC_RS16925	COG1802	Transcriptional regulator
AZC_RS16930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_RS16935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS16950	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AZC_RS16960	COG4191	Histidine kinase
AZC_RS16965	COG4566	intracellular signal transduction
AZC_RS16975	COG1914	H( )-stimulated, divalent metal cation uptake system
AZC_RS16980	COG2186	Transcriptional regulator
AZC_RS16990	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_RS16995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS17010	COG1305	Transglutaminase-like
AZC_RS17015	COG2308	Evidence 4 Homologs of previously reported genes of
AZC_RS17015	COG2307	Protein conserved in bacteria
AZC_RS17030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS17035	COG0653	protein targeting
AZC_RS17050	COG2274	protein secretion by the type I secretion system
AZC_RS17055	COG0154	amidase activity
AZC_RS17060	COG5265	(ABC) transporter
AZC_RS17065	COG3034	peptidoglycan biosynthetic process
AZC_RS17070	COG0825	malonyl-CoA metabolic process
AZC_RS17085	COG1872	DUF167
AZC_RS17120	COG1216	Glycosyl transferase, family 2
AZC_RS17120	COG0438	transferase activity, transferring glycosyl groups
AZC_RS17130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS17140	COG1846	Transcriptional regulator
AZC_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS17170	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZC_RS17185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS17190	COG1802	Transcriptional regulator
AZC_RS17195	COG2721	sulfolactate sulfo-lyase activity
AZC_RS17205	COG1904	glucuronate isomerase
AZC_RS17230	COG0246	Mannitol dehydrogenase
AZC_RS17255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZC_RS17260	COG1301	dicarboxylic acid transport
AZC_RS17280	COG0583	DNA-binding transcription factor activity
AZC_RS17305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZC_RS17310	COG0489	protein tyrosine kinase activity
AZC_RS17315	COG1573	uracil-dna glycosylase
AZC_RS17320	COG0625	glutathione transferase activity
AZC_RS17350	COG0477	Major facilitator Superfamily
AZC_RS17355	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZC_RS17365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZC_RS17370	COG0077	Prephenate dehydratase
AZC_RS17370	COG1605	Chorismate mutase
AZC_RS17380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZC_RS17390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_RS17400	COG0714	Associated with various cellular activities
AZC_RS17450	COG2188	Transcriptional regulator
AZC_RS17455	COG3624	Phosphonate C-P lyase system protein PhnG
AZC_RS17460	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AZC_RS17465	COG3626	phosphonate metabolism
AZC_RS17470	COG3627	carbon phosphorus lyase activity
AZC_RS17480	COG4107	phosphonate C-P lyase system protein PhnK
AZC_RS17485	COG4778	phosphonate C-P lyase system protein PhnL
AZC_RS17490	COG3454	Phosphonate metabolism
AZC_RS17495	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_RS17540	COG0316	Belongs to the HesB IscA family
AZC_RS17550	COG1104	cysteine desulfurase activity
AZC_RS17555	COG5554	nitrogen fixation
AZC_RS17570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZC_RS17590	COG5554	nitrogen fixation
AZC_RS17610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZC_RS17670	COG2151	metal-sulfur cluster biosynthetic enzyme
AZC_RS17685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZC_RS17710	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZC_RS17730	COG2086	electron transfer activity
AZC_RS17735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZC_RS17740	COG0644	oxidoreductase
AZC_RS17745	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AZC_RS17750	COG5420	small protein containing a coiled-coil domain
AZC_RS17765	COG3383	formate dehydrogenase (NAD+) activity
AZC_RS17770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZC_RS17785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS17800	COG2267	carboxylic ester hydrolase activity
AZC_RS17810	COG1253	flavin adenine dinucleotide binding
AZC_RS17820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_RS17845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZC_RS17870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_RS17895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZC_RS17920	COG3220	belongs to the UPF0276 family
AZC_RS17935	COG3960	tartronate-semialdehyde synthase activity
AZC_RS17940	COG3622	Belongs to the hyi family
AZC_RS17945	COG2084	Dehydrogenase
AZC_RS17955	COG2954	triphosphatase activity
AZC_RS17975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZC_RS17990	COG2857	Cytochrome c1
AZC_RS17990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZC_RS17995	COG2857	Cytochrome c1
AZC_RS17995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZC_RS18000	COG0723	plastoquinol--plastocyanin reductase activity
AZC_RS18005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZC_RS18010	COG0408	coproporphyrinogen oxidase activity
AZC_RS18020	COG0617	tRNA 3'-terminal CCA addition
AZC_RS18040	COG0714	Associated with various cellular activities
AZC_RS18080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZC_RS18080	COG2755	lipolytic protein G-D-S-L family
AZC_RS18085	COG1177	transmembrane transport
AZC_RS18090	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_RS18095	COG3842	ATPase activity
AZC_RS18110	COG1819	glycosyl
AZC_RS18115	COG2814	Major facilitator Superfamily
AZC_RS18155	COG0129	dihydroxy-acid dehydratase activity
AZC_RS18160	COG3237	CsbD-like
AZC_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS18190	COG1253	flavin adenine dinucleotide binding
AZC_RS18195	COG2066	Belongs to the glutaminase family
AZC_RS18200	COG2203	Gaf domain
AZC_RS18200	COG3706	GGDEF domain
AZC_RS18200	COG5001	Diguanylate cyclase
AZC_RS18200	COG4251	negative regulation of phosphorylation
AZC_RS18205	COG5001	Diguanylate cyclase
AZC_RS18205	COG3300	MHYT domain
AZC_RS18210	COG0352	thiamine-phosphate diphosphorylase activity
AZC_RS18220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_RS18230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZC_RS18275	COG2022	thiamine diphosphate biosynthetic process
AZC_RS18285	COG2022	thiamine diphosphate biosynthetic process
AZC_RS18285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS18290	COG1846	Transcriptional regulator
AZC_RS18305	COG1960	acyl-CoA dehydrogenase activity
AZC_RS18335	COG4303	Ethanolamine ammonia lyase large subunit
AZC_RS18370	COG0582	viral genome integration into host DNA
AZC_RS18600	COG0316	Belongs to the HesB IscA family
AZC_RS18610	COG2151	metal-sulfur cluster biosynthetic enzyme
AZC_RS18615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_RS18620	COG0719	Fe-S assembly protein
AZC_RS18625	COG0396	ATPase activity
AZC_RS18635	COG1104	cysteine desulfurase activity
AZC_RS18640	COG2945	thiolester hydrolase activity
AZC_RS18645	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AZC_RS18650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZC_RS18665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZC_RS18685	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZC_RS18690	COG1530	ribonuclease E activity
AZC_RS18690	COG1530	ribonuclease E activity
AZC_RS18695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZC_RS18700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZC_RS18705	COG0363	glucosamine-6-phosphate deaminase activity
AZC_RS18710	COG0166	Belongs to the GPI family
AZC_RS18730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_RS18740	COG1802	Transcriptional regulator
AZC_RS18745	COG0505	Belongs to the CarA family
AZC_RS18765	COG0358	DNA primase activity
AZC_RS18770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZC_RS18785	COG0747	negative chemotaxis
AZC_RS18795	COG0174	glutamine synthetase
AZC_RS18805	COG0784	Response regulator, receiver
AZC_RS18810	COG0745	RESPONSE REGULATOR receiver
AZC_RS18825	COG1703	isobutyryl-CoA mutase activity
AZC_RS18835	COG0280	phosphate acetyltransferase
AZC_RS18835	COG0281	malic enzyme
AZC_RS18850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZC_RS18860	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AZC_RS18880	COG0248	Ppx GppA phosphatase
AZC_RS18885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZC_RS18890	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZC_RS18895	COG0516	GMP reductase activity
AZC_RS18895	COG0517	IMP dehydrogenase activity
AZC_RS18930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZC_RS18975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZC_RS18995	COG1309	transcriptional regulator
AZC_RS19010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZC_RS19015	COG2011	ABC-type metal ion transport system permease component
AZC_RS19020	COG1464	Belongs to the NlpA lipoprotein family
AZC_RS19040	COG0583	DNA-binding transcription factor activity
AZC_RS19045	COG1942	4-Oxalocrotonate Tautomerase
AZC_RS19080	COG0519	Catalyzes the synthesis of GMP from XMP
AZC_RS19080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZC_RS19105	COG0552	protein localization to endoplasmic reticulum
AZC_RS19110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_RS19115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZC_RS19125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZC_RS19145	COG0776	regulation of translation
AZC_RS19150	COG0616	signal peptide processing
AZC_RS19155	COG0840	transmembrane signaling receptor activity
AZC_RS19160	COG0539	negative regulation of cytoplasmic translation
AZC_RS19200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_RS19205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_RS19210	COG0427	acetyl-CoA hydrolase
AZC_RS19225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZC_RS19240	COG4208	sulfate ABC transporter
AZC_RS19265	COG2030	dehydratase
AZC_RS19280	COG3047	cAMP biosynthetic process
AZC_RS19290	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AZC_RS19315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_RS19320	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS19330	COG0129	dihydroxy-acid dehydratase activity
AZC_RS19335	COG3128	pkhd-type hydroxylase
AZC_RS19340	COG4774	siderophore transport
AZC_RS19345	COG1122	ATPase activity
AZC_RS19355	COG1268	BioY protein
AZC_RS19365	COG1271	oxidase subunit
AZC_RS19370	COG1294	oxidase, subunit
AZC_RS19380	COG0577	efflux transmembrane transporter activity
AZC_RS19380	COG1136	(ABC) transporter
AZC_RS19385	COG1136	(ABC) transporter
AZC_RS19405	COG0488	(ABC) transporter
AZC_RS19425	COG2072	flavoprotein involved in K transport
AZC_RS19435	COG0601	transmembrane transport
AZC_RS19440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_RS19450	COG0444	Belongs to the ABC transporter superfamily
AZC_RS19460	COG0747	negative chemotaxis
AZC_RS19510	COG4106	trans-aconitate 2-methyltransferase activity
AZC_RS19515	COG0488	(ABC) transporter
AZC_RS19535	COG4977	sequence-specific DNA binding
AZC_RS19605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZC_RS19615	COG2192	nodulation
AZC_RS19625	COG1215	transferase activity, transferring glycosyl groups
AZC_RS19635	COG3153	acetyltransferase
AZC_RS19660	COG1858	cytochrome C peroxidase
AZC_RS19685	COG0741	lytic transglycosylase activity
AZC_RS19705	COG1192	Involved in chromosome partitioning
AZC_RS19720	COG5489	Protein of unknown function (DUF736)
AZC_RS19735	COG4691	Plasmid stability protein
AZC_RS19795	COG3177	Filamentation induced by cAMP protein fic
AZC_RS19805	COG4962	Type ii secretion system protein e
AZC_RS19820	COG3451	type IV secretory pathway VirB4
AZC_RS19835	COG3846	protein secretion by the type IV secretion system
AZC_RS19840	COG3701	Conjugal transfer protein
AZC_RS19850	COG2948	multi-organism process
AZC_RS19865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS19870	COG0765	amino acid transport
AZC_RS19875	COG0765	amino acid transport
AZC_RS19880	COG0165	Argininosuccinate lyase
AZC_RS19890	COG1126	abc transporter atp-binding protein
AZC_RS19895	COG1760	l-serine dehydratase
AZC_RS19915	COG1476	TRANSCRIPTIONal
AZC_RS19920	COG4974	Belongs to the 'phage' integrase family
AZC_RS19950	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS19990	COG1116	anion transmembrane transporter activity
AZC_RS19995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZC_RS20000	COG0300	oxidoreductase activity
AZC_RS20010	COG1335	isochorismatase
AZC_RS20025	COG0183	Belongs to the thiolase family
AZC_RS20045	COG1525	nuclease
AZC_RS20050	COG2202	Pas domain
AZC_RS20050	COG2205	protein histidine kinase activity
AZC_RS20065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS20070	COG0728	peptidoglycan biosynthetic process
AZC_RS20075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZC_RS20080	COG3706	GGDEF domain
AZC_RS20085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AZC_RS20105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZC_RS20110	COG2226	methyltransferase
AZC_RS20130	COG2205	protein histidine kinase activity
AZC_RS20135	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZC_RS20140	COG1137	ATPase activity
AZC_RS20155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_RS20175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZC_RS20180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZC_RS20220	COG0024	Methionine aminopeptidase
AZC_RS20225	COG2099	Precorrin-6x reductase
AZC_RS20245	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZC_RS20250	COG1797	cobyrinic acid a,c-diamide synthase activity
AZC_RS20280	COG0228	four-way junction DNA binding
AZC_RS20285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZC_RS20290	COG0336	Belongs to the RNA methyltransferase TrmD family
AZC_RS20295	COG0335	large ribosomal subunit rRNA binding
AZC_RS20305	COG0435	Glutathione S-transferase
AZC_RS20320	COG0673	inositol 2-dehydrogenase activity
AZC_RS20335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_RS20350	COG0322	excinuclease ABC activity
AZC_RS20355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZC_RS20365	COG0314	molybdopterin synthase activity
AZC_RS20370	COG5001	Diguanylate cyclase
AZC_RS20370	COG4251	negative regulation of phosphorylation
AZC_RS20370	COG3706	GGDEF domain
AZC_RS20370	COG2203	Gaf domain
AZC_RS20375	COG5001	Diguanylate cyclase
AZC_RS20375	COG3706	GGDEF domain
AZC_RS20375	COG2203	Gaf domain
AZC_RS20375	COG4251	negative regulation of phosphorylation
AZC_RS20380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZC_RS20385	COG1846	Transcriptional regulator
AZC_RS20390	COG0745	RESPONSE REGULATOR receiver
AZC_RS20405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZC_RS20430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZC_RS20440	COG1496	oxidoreductase activity
AZC_RS20450	COG0642	Histidine kinase
AZC_RS20470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_RS20485	COG1538	Outer membrane efflux protein
AZC_RS20495	COG1136	(ABC) transporter
AZC_RS20510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZC_RS20515	COG0671	phosphoesterase, PA-phosphatase related
AZC_RS20520	COG1671	Belongs to the UPF0178 family
AZC_RS20530	COG1695	Transcriptional regulator
AZC_RS20535	COG4974	Belongs to the 'phage' integrase family
AZC_RS20540	COG2755	lipolytic protein G-D-S-L family
AZC_RS20540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZC_RS20560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZC_RS20565	COG1280	lysine exporter protein (LysE YggA)
AZC_RS20570	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_RS20580	COG0567	Dehydrogenase, E1 component
AZC_RS20590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZC_RS20595	COG0045	succinate-CoA ligase (ADP-forming) activity
AZC_RS20600	COG0039	L-malate dehydrogenase activity
AZC_RS20605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZC_RS20620	COG0717	Belongs to the dCTP deaminase family
AZC_RS20635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_RS20640	COG2967	ApaG domain
AZC_RS20645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZC_RS20655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZC_RS20660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_RS20680	COG0745	RESPONSE REGULATOR receiver
AZC_RS20685	COG0704	Plays a role in the regulation of phosphate uptake
AZC_RS20690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZC_RS20700	COG0573	inorganic phosphate transmembrane transporter activity
AZC_RS20725	COG3158	transport of potassium into the cell
AZC_RS20730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZC_RS20745	COG1278	Cold shock
AZC_RS20750	COG0778	Nitroreductase
AZC_RS20770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZC_RS20780	COG2353	YceI-like domain
AZC_RS20785	COG0706	membrane insertase activity
AZC_RS20790	COG0594	ribonuclease P activity
AZC_RS20795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZC_RS20800	COG4651	solute:proton antiporter activity
AZC_RS20800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZC_RS20805	COG0066	3-isopropylmalate dehydratase activity
AZC_RS20810	COG3038	cytochrome b561
AZC_RS20820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZC_RS20835	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AZC_RS20845	COG0745	RESPONSE REGULATOR receiver
AZC_RS20850	COG2205	protein histidine kinase activity
AZC_RS20860	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_RS20860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZC_RS20865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_RS20870	COG3852	Histidine kinase
AZC_RS20885	COG1984	allophanate hydrolase subunit 2
AZC_RS20895	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZC_RS20925	COG4336	lyase activity
AZC_RS20930	COG0583	DNA-binding transcription factor activity
AZC_RS20945	COG1660	Displays ATPase and GTPase activities
AZC_RS20965	COG2326	polyphosphate kinase activity
AZC_RS20970	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZC_RS20975	COG0494	nUDIX hydrolase
AZC_RS20990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZC_RS20995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZC_RS21000	COG1607	acyl-coa hydrolase
AZC_RS21010	COG5001	Diguanylate cyclase
AZC_RS21010	COG4251	negative regulation of phosphorylation
AZC_RS21010	COG3706	GGDEF domain
AZC_RS21010	COG2203	Gaf domain
AZC_RS21020	COG2226	methyltransferase
AZC_RS21065	COG2198	Histidine kinase
AZC_RS21065	COG2205	protein histidine kinase activity
AZC_RS21065	COG0784	Response regulator, receiver
AZC_RS21070	COG0745	RESPONSE REGULATOR receiver
AZC_RS21075	COG1595	DNA-templated transcription, initiation
AZC_RS21090	COG0488	(ABC) transporter
AZC_RS21100	COG0366	Alpha amylase catalytic
AZC_RS21105	COG0366	Alpha amylase catalytic
AZC_RS21110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZC_RS21115	COG1640	4-alpha-glucanotransferase
AZC_RS21135	COG0783	Belongs to the Dps family
AZC_RS21145	COG0583	DNA-binding transcription factor activity
AZC_RS21150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZC_RS21155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZC_RS21160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZC_RS21165	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZC_RS21170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZC_RS21180	COG0765	amino acid transport
AZC_RS21185	COG0765	amino acid transport
AZC_RS21195	COG0793	Belongs to the peptidase S41A family
AZC_RS21205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZC_RS21210	COG0799	negative regulation of ribosome biogenesis
AZC_RS21215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZC_RS21220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZC_RS21235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZC_RS21260	COG3258	Cytochrome c
AZC_RS21265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZC_RS21270	COG0193	aminoacyl-tRNA hydrolase activity
AZC_RS21285	COG0012	GTP binding
AZC_RS21300	COG0667	Aldo Keto reductase
AZC_RS21310	COG0105	UTP biosynthetic process
AZC_RS21315	COG0861	Integral membrane protein TerC family
AZC_RS21320	COG0861	Integral membrane protein TerC family
AZC_RS21325	COG0243	molybdopterin cofactor binding
AZC_RS21335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZC_RS21340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZC_RS21345	COG0583	DNA-binding transcription factor activity
AZC_RS21395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_RS21395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS21415	COG0445	tRNA wobble uridine modification
AZC_RS21420	COG0028	Belongs to the TPP enzyme family
AZC_RS21455	COG5487	UPF0391 membrane protein
AZC_RS21465	COG0039	L-malate dehydrogenase activity
AZC_RS21480	COG2368	4-hydroxyphenylacetate
AZC_RS21485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_RS21510	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS21545	COG0739	heme binding
AZC_RS21575	COG1309	transcriptional regulator
AZC_RS21580	COG0024	Methionine aminopeptidase
AZC_RS21585	COG2003	Belongs to the UPF0758 family
AZC_RS21600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_RS21605	COG3842	ATPase activity
AZC_RS21615	COG1175	transmembrane transport
AZC_RS21620	COG0395	ABC-type sugar transport system, permease component
AZC_RS21630	COG1366	Belongs to the anti-sigma-factor antagonist family
AZC_RS21685	COG2271	Major facilitator Superfamily
AZC_RS21690	COG0277	FAD linked oxidase domain protein
AZC_RS21695	COG0004	ammonium transporteR
AZC_RS21700	COG0347	Belongs to the P(II) protein family
AZC_RS21705	COG1946	Acyl-CoA thioesterase
AZC_RS21710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_RS21725	COG2835	tetraacyldisaccharide 4'-kinase activity
AZC_RS21730	COG0697	spore germination
AZC_RS21735	COG0124	histidyl-tRNA synthetase
AZC_RS21755	COG1489	DNA binding
AZC_RS21760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZC_RS21765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZC_RS21775	COG0612	Peptidase, M16
AZC_RS21780	COG0612	Peptidase, M16
AZC_RS21790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_RS21795	COG0509	glycine decarboxylation via glycine cleavage system
AZC_RS21805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZC_RS21810	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZC_RS21815	COG0697	spore germination
AZC_RS21820	COG1620	l-lactate permease
AZC_RS21830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZC_RS21835	COG0564	pseudouridine synthase activity
AZC_RS21845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_RS21855	COG1196	nuclear chromosome segregation
AZC_RS21865	COG0356	it plays a direct role in the translocation of protons across the membrane
AZC_RS21870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZC_RS21875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZC_RS21880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZC_RS21890	COG0071	Belongs to the small heat shock protein (HSP20) family
AZC_RS21925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZC_RS21930	COG0330	HflC and HflK could
AZC_RS21940	COG3279	Response regulator of the LytR AlgR family
AZC_RS21950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZC_RS21965	COG0840	transmembrane signaling receptor activity
AZC_RS21970	COG1335	isochorismatase
AZC_RS21990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZC_RS22005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZC_RS22010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZC_RS22025	COG1937	Protein conserved in bacteria
AZC_RS22035	COG1040	competence protein
AZC_RS22060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_RS22065	COG0180	Tryptophanyl-tRNA synthetase
AZC_RS22070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_RS22090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZC_RS22095	COG0360	Binds together with S18 to 16S ribosomal RNA
AZC_RS22115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZC_RS22125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_RS22130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_RS22135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZC_RS22140	COG1561	YicC-like family, N-terminal region
AZC_RS22155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZC_RS22160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZC_RS22170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZC_RS22185	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AZC_RS22195	COG1160	GTP binding
AZC_RS22210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZC_RS22250	COG2226	methyltransferase
AZC_RS22265	COG0606	chelatase, subunit chli
AZC_RS22270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_RS22280	COG2226	methyltransferase
AZC_RS22290	COG0189	ligase activity
AZC_RS22295	COG2226	methyltransferase
AZC_RS22300	COG0482	sulfurtransferase activity
AZC_RS22310	COG0326	Molecular chaperone. Has ATPase activity
AZC_RS22330	COG3260	NADH ubiquinone oxidoreductase 20
AZC_RS22335	COG0649	NAD binding
AZC_RS22340	COG0651	ATP synthesis coupled electron transport
AZC_RS22350	COG0650	Formate hydrogenlyase subunit 4
AZC_RS22355	COG0651	ATP synthesis coupled electron transport
AZC_RS22380	COG0745	RESPONSE REGULATOR receiver
AZC_RS22390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_RS22400	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS22405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_RS22430	COG1802	Transcriptional regulator
AZC_RS22435	COG0402	S-adenosylhomocysteine deaminase activity
AZC_RS22440	COG0667	Aldo Keto reductase
AZC_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS22450	COG0252	asparaginase activity
AZC_RS22465	COG4771	TonB-dependent receptor
AZC_RS22470	COG4558	Periplasmic binding protein
AZC_RS22475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_RS22480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZC_RS22495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS22500	COG1129	ABC transporter
AZC_RS22500	COG0842	Transport permease protein
AZC_RS22505	COG0842	Transport permease protein
AZC_RS22510	COG0443	Heat shock 70 kDa protein
AZC_RS22520	COG1175	transmembrane transport
AZC_RS22525	COG0395	ABC-type sugar transport system, permease component
AZC_RS22540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_RS22545	COG3665	Urea carboxylase-associated protein
AZC_RS22550	COG3665	Urea carboxylase-associated protein
AZC_RS22565	COG1609	Transcriptional regulator
AZC_RS22570	COG0765	amino acid transport
AZC_RS22575	COG0765	amino acid transport
AZC_RS22580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_RS22585	COG1126	abc transporter atp-binding protein
AZC_RS22590	COG3734	2-keto-3-deoxy-galactonokinase
AZC_RS22595	COG0800	Aldolase
AZC_RS22605	COG0477	Major facilitator Superfamily
AZC_RS22625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZC_RS22650	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZC_RS22675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_RS22685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZC_RS22700	COG0154	amidase activity
AZC_RS22715	COG4774	siderophore transport
AZC_RS22720	COG2309	aminopeptidase activity
AZC_RS22775	COG2972	Histidine kinase
AZC_RS22775	COG0840	transmembrane signaling receptor activity
AZC_RS22780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_RS22785	COG0174	glutamine synthetase
AZC_RS22795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZC_RS22810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZC_RS22815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZC_RS22820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZC_RS22825	COG0072	phenylalanine-tRNA ligase activity
AZC_RS22825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZC_RS22835	COG0142	geranyltranstransferase activity
AZC_RS22840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZC_RS22845	COG2917	probably involved in intracellular septation
AZC_RS22850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_RS22860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZC_RS22870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZC_RS22875	COG4133	protoheme IX ABC transporter activity
AZC_RS22880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZC_RS22895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_RS22895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_RS22900	COG1309	transcriptional regulator
AZC_RS22905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_RS22930	COG0792	nuclease activity
AZC_RS22935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZC_RS22955	COG0210	DNA helicase
AZC_RS22965	COG2264	protein methyltransferase activity
AZC_RS22980	COG0277	FAD linked oxidase domain protein
AZC_RS23005	COG4974	Belongs to the 'phage' integrase family
AZC_RS23010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZC_RS23015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZC_RS23030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZC_RS23035	COG2890	protein-(glutamine-N5) methyltransferase activity
AZC_RS23050	COG1072	(Pantothenic acid kinase))
AZC_RS23055	COG0140	phosphoribosyl-ATP diphosphatase activity
AZC_RS23060	COG0107	imidazoleglycerol-phosphate synthase activity
AZC_RS23065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZC_RS23070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZC_RS23080	COG0131	Imidazoleglycerol-phosphate dehydratase
AZC_RS23095	COG2267	carboxylic ester hydrolase activity
AZC_RS23110	COG2902	Dehydrogenase
AZC_RS23140	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS23155	COG1741	Belongs to the pirin family
AZC_RS23165	COG1309	transcriptional regulator
AZC_RS23175	COG1131	(ABC) transporter
AZC_RS23185	COG3278	Belongs to the heme-copper respiratory oxidase family
AZC_RS23200	COG2010	Cytochrome c
AZC_RS23215	COG2217	Heavy metal translocating P-type atpase
AZC_RS23230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_RS23235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_RS23245	COG0183	Belongs to the thiolase family
AZC_RS23265	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS23275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZC_RS23285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZC_RS23300	COG0275	rRNA processing
AZC_RS23305	COG2001	Belongs to the MraZ family
AZC_RS23315	COG3023	N-Acetylmuramoyl-L-alanine amidase
AZC_RS23335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_RS23345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZC_RS23350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZC_RS23365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZC_RS23370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZC_RS23375	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZC_RS23380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZC_RS23385	COG0849	cell division
AZC_RS23390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZC_RS23405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZC_RS23410	COG0497	DNA recombination
AZC_RS23415	COG1309	transcriptional regulator
AZC_RS23420	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS23425	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS23450	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_RS23470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZC_RS23475	COG2353	YceI-like domain
AZC_RS23500	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_RS23520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZC_RS23525	COG1024	Enoyl-CoA hydratase
AZC_RS23530	COG4770	biotin carboxylase activity
AZC_RS23535	COG0519	Catalyzes the synthesis of GMP from XMP
AZC_RS23535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZC_RS23545	COG0564	pseudouridine synthase activity
AZC_RS23555	COG0583	DNA-binding transcription factor activity
AZC_RS23570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZC_RS23615	COG0037	tRNA processing
AZC_RS23615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZC_RS23620	COG2884	Cell division ATP-binding protein ftsE
AZC_RS23645	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZC_RS23655	COG0287	Prephenate dehydrogenase
AZC_RS23660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZC_RS23680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_RS23680	COG2080	2 iron, 2 sulfur cluster binding
AZC_RS23685	COG2252	PERMEase
AZC_RS23690	COG0402	S-adenosylhomocysteine deaminase activity
AZC_RS23695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZC_RS23700	COG0438	transferase activity, transferring glycosyl groups
AZC_RS23715	COG1596	polysaccharide export
AZC_RS23760	COG0438	transferase activity, transferring glycosyl groups
AZC_RS23765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZC_RS23770	COG0167	dihydroorotate dehydrogenase activity
AZC_RS23775	COG1970	mechanosensitive ion channel activity
AZC_RS23780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_RS23790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_RS23795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZC_RS23830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZC_RS23835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_RS23840	COG4191	Histidine kinase
AZC_RS23845	COG4566	intracellular signal transduction
AZC_RS23850	COG4566	intracellular signal transduction
AZC_RS23855	COG0045	succinate-CoA ligase (ADP-forming) activity
AZC_RS23855	COG1042	CoA-binding domain protein
AZC_RS23855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_RS23860	COG5001	Diguanylate cyclase
AZC_RS23865	COG0019	diaminopimelate decarboxylase activity
AZC_RS23875	COG0778	Nitroreductase
AZC_RS23880	COG0165	Argininosuccinate lyase
AZC_RS23885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_RS23900	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_RS23905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZC_RS23910	COG2086	electron transfer activity
AZC_RS23915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_RS23925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZC_RS23930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZC_RS23940	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZC_RS23955	COG1968	undecaprenyl-diphosphatase activity
AZC_RS23965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZC_RS23995	COG2378	regulation of single-species biofilm formation
AZC_RS24005	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZC_RS24010	COG0583	DNA-binding transcription factor activity
AZC_RS24015	COG0778	Nitroreductase
AZC_RS24030	COG2259	Doxx family
AZC_RS24065	COG0138	bifunctional purine biosynthesis protein purh
AZC_RS24090	COG0501	Belongs to the peptidase M48B family
AZC_RS24100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZC_RS24105	COG1214	PFAM Peptidase M22, glycoprotease
AZC_RS24125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZC_RS24130	COG0445	tRNA wobble uridine modification
AZC_RS24135	COG0357	Ribosomal RNA small subunit methyltransferase G
AZC_RS24150	COG0306	phosphate transporter
AZC_RS24155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZC_RS24160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZC_RS24165	COG1981	membrane
AZC_RS24285	COG3706	GGDEF domain
AZC_RS24290	COG5001	Diguanylate cyclase
AZC_RS24290	COG4251	negative regulation of phosphorylation
AZC_RS24290	COG3706	GGDEF domain
AZC_RS24290	COG2203	Gaf domain
AZC_RS24295	COG0840	transmembrane signaling receptor activity
AZC_RS24315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZC_RS24365	COG3852	Histidine kinase
AZC_RS24415	COG0438	transferase activity, transferring glycosyl groups
AZC_RS24415	COG1216	Glycosyl transferase, family 2
AZC_RS24440	COG2815	serine threonine protein kinase
AZC_RS24440	COG0515	serine threonine protein kinase
AZC_RS24450	COG0726	polysaccharide deacetylase
AZC_RS24455	COG1017	nitric oxide dioxygenase activity
AZC_RS24455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZC_RS24460	COG3706	GGDEF domain
AZC_RS24475	COG0726	polysaccharide deacetylase
AZC_RS24500	COG1309	transcriptional regulator
AZC_RS24535	COG3773	Cell wall hydrolase
AZC_RS24535	COG3409	Peptidoglycan-binding domain 1 protein
AZC_RS24540	COG3300	MHYT domain
AZC_RS24540	COG5001	Diguanylate cyclase
AZC_RS24555	COG1131	(ABC) transporter
AZC_RS24570	COG0438	transferase activity, transferring glycosyl groups
AZC_RS24575	COG0438	transferase activity, transferring glycosyl groups
AZC_RS24580	COG2770	Histidine kinase
AZC_RS24580	COG2208	phosphoserine phosphatase activity