locus-tag	class	description
DSUI_RS00010	COG0425	Belongs to the sulfur carrier protein TusA family
DSUI_RS00020	COG0315	cyclic pyranopterin monophosphate synthase activity
DSUI_RS00035	COG1278	Cold shock
DSUI_RS00040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DSUI_RS00045	COG0542	response to heat
DSUI_RS00050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSUI_RS00055	COG2224	Isocitrate lyase
DSUI_RS00070	COG2860	membrane
DSUI_RS00080	COG0583	DNA-binding transcription factor activity
DSUI_RS00090	COG0730	response to heat
DSUI_RS00095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSUI_RS00100	COG0647	UMP catabolic process
DSUI_RS00115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSUI_RS00130	COG1253	flavin adenine dinucleotide binding
DSUI_RS00135	COG1380	Effector of murein hydrolase LrgA
DSUI_RS00140	COG1346	cytolysis
DSUI_RS00150	COG0670	Belongs to the BI1 family
DSUI_RS00155	COG2076	Multidrug Resistance protein
DSUI_RS00160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSUI_RS00165	COG0501	Belongs to the peptidase M48B family
DSUI_RS00185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSUI_RS00190	COG0537	adenosine 5'-monophosphoramidase activity
DSUI_RS00195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSUI_RS00200	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DSUI_RS00220	COG0708	Exodeoxyribonuclease III
DSUI_RS00230	COG0339	signal peptide processing
DSUI_RS00240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSUI_RS00255	COG0778	Nitroreductase
DSUI_RS00270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSUI_RS00275	COG0438	transferase activity, transferring glycosyl groups
DSUI_RS00300	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DSUI_RS00310	COG2076	Multidrug Resistance protein
DSUI_RS00360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSUI_RS00380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSUI_RS00390	COG2089	acid synthase
DSUI_RS00405	COG1083	cytidylyl-transferase
DSUI_RS00410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSUI_RS00415	COG1086	Polysaccharide biosynthesis protein
DSUI_RS00420	COG1132	(ABC) transporter
DSUI_RS00425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DSUI_RS00430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSUI_RS00435	COG0662	Cupin 2, conserved barrel domain protein
DSUI_RS00435	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DSUI_RS00445	COG0840	transmembrane signaling receptor activity
DSUI_RS00450	COG0009	L-threonylcarbamoyladenylate synthase
DSUI_RS00455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DSUI_RS00460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSUI_RS00465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSUI_RS00495	COG2823	Periplasmic or secreted lipoprotein
DSUI_RS00500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSUI_RS00530	COG2833	Protein of unknown function (DUF455)
DSUI_RS00535	COG0750	zinc metalloprotease
DSUI_RS00545	COG0745	RESPONSE REGULATOR receiver
DSUI_RS00545	COG2972	Histidine kinase
DSUI_RS00550	COG0165	Argininosuccinate lyase
DSUI_RS00555	COG2815	serine threonine protein kinase
DSUI_RS00555	COG0515	serine threonine protein kinase
DSUI_RS00565	COG0004	ammonium transporteR
DSUI_RS00585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DSUI_RS00595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSUI_RS00600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DSUI_RS00605	COG1490	D-aminoacyl-tRNA deacylase activity
DSUI_RS00615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSUI_RS00620	COG1012	belongs to the aldehyde dehydrogenase family
DSUI_RS00625	COG1139	Iron-sulfur cluster binding protein
DSUI_RS00645	COG0281	malic enzyme
DSUI_RS00645	COG0280	phosphate acetyltransferase
DSUI_RS00650	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSUI_RS00655	COG0436	Aminotransferase
DSUI_RS00695	COG3253	May function as heme-dependent peroxidase
DSUI_RS00700	COG3381	protein complex oligomerization
DSUI_RS00705	COG1140	nitrate reductase beta subunit
DSUI_RS00710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DSUI_RS00720	COG3852	Histidine kinase
DSUI_RS00730	COG4944	Protein of unknown function (DUF1109)
DSUI_RS00735	COG1595	DNA-templated transcription, initiation
DSUI_RS00740	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DSUI_RS00745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSUI_RS00760	COG0142	geranyltranstransferase activity
DSUI_RS00765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSUI_RS00770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSUI_RS00775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSUI_RS00780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DSUI_RS00785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DSUI_RS00790	COG0134	indole-3-glycerol-phosphate synthase activity
DSUI_RS00795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSUI_RS00835	COG0419	ATPase involved in DNA repair
DSUI_RS00875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSUI_RS00905	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DSUI_RS01040	COG0582	viral genome integration into host DNA
DSUI_RS01050	COG0546	phosphoglycolate phosphatase activity
DSUI_RS01055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSUI_RS01060	COG2967	ApaG domain
DSUI_RS01065	COG2226	methyltransferase
DSUI_RS01075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSUI_RS01080	COG0653	protein targeting
DSUI_RS01085	COG0739	heme binding
DSUI_RS01100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DSUI_RS01105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DSUI_RS01115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DSUI_RS01120	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSUI_RS01125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSUI_RS01130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSUI_RS01135	COG0772	Belongs to the SEDS family
DSUI_RS01140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSUI_RS01145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSUI_RS01150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSUI_RS01155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSUI_RS01165	COG3116	cell division
DSUI_RS01170	COG0275	rRNA processing
DSUI_RS01175	COG2001	Belongs to the MraZ family
DSUI_RS01190	COG0418	dihydroorotase activity
DSUI_RS01195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSUI_RS01200	COG0792	nuclease activity
DSUI_RS01210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSUI_RS01225	COG1469	GTP cyclohydrolase I activity
DSUI_RS01230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSUI_RS01235	COG4208	sulfate ABC transporter
DSUI_RS01245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DSUI_RS01255	COG1858	cytochrome C peroxidase
DSUI_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS01280	COG1129	ABC transporter
DSUI_RS01280	COG0842	Transport permease protein
DSUI_RS01285	COG0842	Transport permease protein
DSUI_RS01295	COG0745	RESPONSE REGULATOR receiver
DSUI_RS01300	COG2205	protein histidine kinase activity
DSUI_RS01315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DSUI_RS01320	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DSUI_RS01325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DSUI_RS01330	COG1671	Belongs to the UPF0178 family
DSUI_RS01335	COG0459	protein refolding
DSUI_RS01340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSUI_RS01365	COG3162	membrane
DSUI_RS01370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSUI_RS01390	COG2027	D-alanyl-D-alanine carboxypeptidase
DSUI_RS01405	COG1489	DNA binding
DSUI_RS01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS01430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DSUI_RS01435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSUI_RS01460	COG0477	Major facilitator Superfamily
DSUI_RS01465	COG0513	Belongs to the DEAD box helicase family
DSUI_RS01470	COG1607	acyl-coa hydrolase
DSUI_RS01475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSUI_RS01505	COG0183	Belongs to the thiolase family
DSUI_RS01510	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSUI_RS01510	COG1024	Enoyl-CoA hydratase
DSUI_RS01515	COG0318	PFAM AMP-dependent synthetase and ligase
DSUI_RS01525	COG2067	long-chain fatty acid transport protein
DSUI_RS01530	COG1607	acyl-coa hydrolase
DSUI_RS01540	COG1307	EDD domain protein, DegV family
DSUI_RS01545	COG0183	Belongs to the thiolase family
DSUI_RS01550	COG1960	acyl-CoA dehydrogenase activity
DSUI_RS01560	COG5265	(ABC) transporter
DSUI_RS01565	COG2205	protein histidine kinase activity
DSUI_RS01565	COG2202	Pas domain
DSUI_RS01580	COG0203	ribosomal protein L17
DSUI_RS01585	COG0202	RNA polymerase activity
DSUI_RS01590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSUI_RS01595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSUI_RS01600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSUI_RS01605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSUI_RS01610	COG0201	protein transport
DSUI_RS01615	COG0200	Binds to the 23S rRNA
DSUI_RS01620	COG1841	ribosomal large subunit assembly
DSUI_RS01625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSUI_RS01630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSUI_RS01635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSUI_RS01640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSUI_RS01645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DSUI_RS01650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSUI_RS01655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSUI_RS01665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSUI_RS01670	COG0255	Belongs to the universal ribosomal protein uL29 family
DSUI_RS01675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DSUI_RS01680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSUI_RS01685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSUI_RS01690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSUI_RS01695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSUI_RS01700	COG0089	rRNA binding
DSUI_RS01705	COG0088	Forms part of the polypeptide exit tunnel
DSUI_RS01710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSUI_RS01715	COG0051	transcription antitermination factor activity, RNA binding
DSUI_RS01720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSUI_RS01725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSUI_RS01730	COG0049	tRNA binding
DSUI_RS01735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSUI_RS01740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSUI_RS01745	COG0085	RNA polymerase activity
DSUI_RS01750	COG0222	ribosome binding
DSUI_RS01755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSUI_RS01760	COG0081	regulation of translation
DSUI_RS01765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSUI_RS01775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSUI_RS01785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSUI_RS01805	COG0277	FAD linked oxidase domain protein
DSUI_RS01835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSUI_RS01845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSUI_RS01850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSUI_RS01855	COG0511	ligase activity, forming carbon-carbon bonds
DSUI_RS01860	COG0439	Biotin carboxylase
DSUI_RS01865	COG2264	protein methyltransferase activity
DSUI_RS01885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSUI_RS01905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSUI_RS01910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DSUI_RS01930	COG0859	PFAM glycosyl transferase family 9
DSUI_RS01950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSUI_RS01955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSUI_RS01960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS01975	COG0601	transmembrane transport
DSUI_RS01980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSUI_RS01985	COG4608	Belongs to the ABC transporter superfamily
DSUI_RS02005	COG0385	Bile acid
DSUI_RS02020	COG3338	carbonate dehydratase activity
DSUI_RS02025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSUI_RS02030	COG0628	permease
DSUI_RS02035	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DSUI_RS02045	COG0583	DNA-binding transcription factor activity
DSUI_RS02050	COG1902	pentaerythritol trinitrate reductase activity
DSUI_RS02080	COG0826	peptidase U32
DSUI_RS02085	COG1530	ribonuclease E activity
DSUI_RS02095	COG0412	Dienelactone hydrolase
DSUI_RS02100	COG1012	belongs to the aldehyde dehydrogenase family
DSUI_RS02105	COG0791	NLP P60 protein
DSUI_RS02120	COG2239	Acts as a magnesium transporter
DSUI_RS02125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSUI_RS02130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSUI_RS02140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DSUI_RS02145	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DSUI_RS02150	COG3150	esterase
DSUI_RS02160	COG1968	undecaprenyl-diphosphatase activity
DSUI_RS02165	COG0424	maF-like protein
DSUI_RS02170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DSUI_RS02175	COG0799	negative regulation of ribosome biogenesis
DSUI_RS02180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSUI_RS02195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSUI_RS02210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSUI_RS02210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSUI_RS02245	COG0438	transferase activity, transferring glycosyl groups
DSUI_RS02250	COG1132	(ABC) transporter
DSUI_RS02255	COG0438	transferase activity, transferring glycosyl groups
DSUI_RS02260	COG0859	PFAM glycosyl transferase family 9
DSUI_RS02270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DSUI_RS02275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DSUI_RS02295	COG0602	queuosine metabolic process
DSUI_RS02310	COG0823	Involved in the tonB-independent uptake of proteins
DSUI_RS02330	COG0824	Thioesterase
DSUI_RS02335	COG2255	four-way junction helicase activity
DSUI_RS02340	COG0632	four-way junction helicase activity
DSUI_RS02345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSUI_RS02360	COG0217	transcriptional regulatory protein
DSUI_RS02365	COG0433	COG0433 Predicted ATPase
DSUI_RS02370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSUI_RS02375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSUI_RS02385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSUI_RS02390	COG0631	protein serine/threonine phosphatase activity
DSUI_RS02395	COG0515	serine threonine protein kinase
DSUI_RS02395	COG2815	serine threonine protein kinase
DSUI_RS02400	COG1561	YicC-like family, N-terminal region
DSUI_RS02405	COG0194	GDP metabolic process
DSUI_RS02410	COG1758	RNA polymerase activity
DSUI_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSUI_RS02420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSUI_RS02425	COG1024	Enoyl-CoA hydratase
DSUI_RS02430	COG0084	hydrolase, TatD family'
DSUI_RS02435	COG3781	membrane
DSUI_RS02440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSUI_RS02440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSUI_RS02455	COG0243	molybdopterin cofactor binding
DSUI_RS02460	COG0437	4 iron, 4 sulfur cluster binding
DSUI_RS02465	COG0348	domain, Protein
DSUI_RS02495	COG4770	biotin carboxylase activity
DSUI_RS02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSUI_RS02505	COG1703	isobutyryl-CoA mutase activity
DSUI_RS02510	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSUI_RS02510	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSUI_RS02515	COG1802	Transcriptional regulator
DSUI_RS02520	COG1024	Enoyl-CoA hydratase
DSUI_RS02525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSUI_RS02530	COG3162	membrane
DSUI_RS02535	COG0730	response to heat
DSUI_RS02555	COG4206	TonB-dependent receptor
DSUI_RS02560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSUI_RS02565	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DSUI_RS02575	COG1797	cobyrinic acid a,c-diamide synthase activity
DSUI_RS02605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSUI_RS02615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DSUI_RS02620	COG1492	cobalamin metabolic process
DSUI_RS02650	COG2391	methyltransferase activity
DSUI_RS02655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DSUI_RS02660	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DSUI_RS02665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DSUI_RS02680	COG5420	small protein containing a coiled-coil domain
DSUI_RS02705	COG2824	Alkylphosphonate utilization operon protein PhnA
DSUI_RS02750	COG3447	MASE1 domain protein
DSUI_RS02750	COG5001	Diguanylate cyclase
DSUI_RS02750	COG5002	protein histidine kinase activity
DSUI_RS02765	COG3411	Ferredoxin
DSUI_RS02810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DSUI_RS02815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DSUI_RS02830	COG1121	(ABC) transporter
DSUI_RS02835	COG0803	Belongs to the bacterial solute-binding protein 9 family
DSUI_RS02850	COG0523	cobalamin synthesis protein
DSUI_RS02855	COG0523	cobalamin synthesis protein
DSUI_RS02865	COG0415	Belongs to the DNA photolyase family
DSUI_RS02875	COG1678	Uncharacterized ACR, COG1678
DSUI_RS02880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DSUI_RS02885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DSUI_RS02890	COG0540	Belongs to the ATCase OTCase family
DSUI_RS02905	COG3279	Response regulator of the LytR AlgR family
DSUI_RS02910	COG1872	DUF167
DSUI_RS02915	COG0762	integral membrane protein
DSUI_RS02945	COG1981	membrane
DSUI_RS02960	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSUI_RS02965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSUI_RS02990	COG1136	(ABC) transporter
DSUI_RS02990	COG0577	efflux transmembrane transporter activity
DSUI_RS03015	COG1595	DNA-templated transcription, initiation
DSUI_RS03035	COG2151	metal-sulfur cluster biosynthetic enzyme
DSUI_RS03065	COG4654	Cytochrome c, class I
DSUI_RS03070	COG1331	Highly conserved protein containing a thioredoxin domain
DSUI_RS03075	COG0583	DNA-binding transcription factor activity
DSUI_RS03080	COG0697	spore germination
DSUI_RS03090	COG0765	amino acid transport
DSUI_RS03095	COG0765	amino acid transport
DSUI_RS03100	COG1126	abc transporter atp-binding protein
DSUI_RS03110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSUI_RS03120	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSUI_RS03130	COG0318	PFAM AMP-dependent synthetase and ligase
DSUI_RS03135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSUI_RS03145	COG1560	Kdo2-lipid A biosynthetic process
DSUI_RS03155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSUI_RS03165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DSUI_RS03185	COG3647	Membrane
DSUI_RS03190	COG0643	Histidine kinase
DSUI_RS03190	COG0784	Response regulator, receiver
DSUI_RS03190	COG2198	Histidine kinase
DSUI_RS03220	COG0351	phosphomethylpyrimidine kinase
DSUI_RS03225	COG0352	thiamine-phosphate diphosphorylase activity
DSUI_RS03230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSUI_RS03235	COG2326	polyphosphate kinase activity
DSUI_RS03265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSUI_RS03270	COG0018	arginyl-trna synthetase
DSUI_RS03280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSUI_RS03300	COG1999	signal sequence binding
DSUI_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
DSUI_RS03310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSUI_RS03315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSUI_RS03320	COG0741	lytic transglycosylase activity
DSUI_RS03335	COG0617	tRNA 3'-terminal CCA addition
DSUI_RS03345	COG0625	glutathione transferase activity
DSUI_RS03380	COG0037	tRNA processing
DSUI_RS03385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSUI_RS03390	COG2815	serine threonine protein kinase
DSUI_RS03390	COG0515	serine threonine protein kinase
DSUI_RS03410	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DSUI_RS03420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSUI_RS03425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DSUI_RS03430	COG1137	ATPase activity
DSUI_RS03435	COG2137	regulation of response to DNA damage stimulus
DSUI_RS03440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSUI_RS03450	COG2193	ferroxidase activity
DSUI_RS03455	COG1546	Belongs to the CinA family
DSUI_RS03460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DSUI_RS03470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSUI_RS03475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DSUI_RS03490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSUI_RS03495	COG4232	protein-disulfide reductase activity
DSUI_RS03520	COG1131	(ABC) transporter
DSUI_RS03530	COG3411	Ferredoxin
DSUI_RS03540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSUI_RS03575	COG1238	metal cluster binding
DSUI_RS03585	COG0432	Pfam Uncharacterised protein family UPF0047
DSUI_RS03590	COG2223	nitrite transmembrane transporter activity
DSUI_RS03595	COG2813	Specifically methylates the guanine in position
DSUI_RS03595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSUI_RS03600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSUI_RS03605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSUI_RS03610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSUI_RS03625	COG0189	ligase activity
DSUI_RS03660	COG0488	(ABC) transporter
DSUI_RS03680	COG0488	(ABC) transporter
DSUI_RS03690	COG5002	protein histidine kinase activity
DSUI_RS03690	COG5001	Diguanylate cyclase
DSUI_RS03705	COG0004	ammonium transporteR
DSUI_RS03720	COG2960	long-chain fatty acid transporting porin activity
DSUI_RS03735	COG0606	chelatase, subunit chli
DSUI_RS03740	COG2814	Major facilitator Superfamily
DSUI_RS03755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSUI_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
DSUI_RS03775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DSUI_RS03785	COG3876	Protein conserved in bacteria
DSUI_RS03810	COG5001	Diguanylate cyclase
DSUI_RS03810	COG4251	negative regulation of phosphorylation
DSUI_RS03810	COG3706	GGDEF domain
DSUI_RS03810	COG2203	Gaf domain
DSUI_RS03815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSUI_RS03850	COG0288	reversible hydration of carbon dioxide
DSUI_RS03865	COG1940	carbohydrate kinase activity
DSUI_RS03870	COG2258	MOSC domain
DSUI_RS03885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSUI_RS03890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DSUI_RS03900	COG0569	domain protein
DSUI_RS03905	COG2204	response regulator
DSUI_RS03920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSUI_RS03920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSUI_RS03925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSUI_RS03935	COG0501	Belongs to the peptidase M48B family
DSUI_RS03940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSUI_RS03945	COG0242	peptide deformylase activity
DSUI_RS03955	COG0758	DNA mediated transformation
DSUI_RS03960	COG2922	Belongs to the Smg family
DSUI_RS03970	COG0783	Belongs to the Dps family
DSUI_RS03975	COG0583	DNA-binding transcription factor activity
DSUI_RS03980	COG1187	pseudouridine synthase activity
DSUI_RS03995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DSUI_RS03995	COG2755	lipolytic protein G-D-S-L family
DSUI_RS04015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSUI_RS04020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DSUI_RS04025	COG0594	ribonuclease P activity
DSUI_RS04030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSUI_RS04035	COG0706	membrane insertase activity
DSUI_RS04040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSUI_RS04085	COG0445	tRNA wobble uridine modification
DSUI_RS04090	COG0357	Ribosomal RNA small subunit methyltransferase G
DSUI_RS04095	COG1192	Involved in chromosome partitioning
DSUI_RS04100	COG1475	DNA binding
DSUI_RS04110	COG0356	it plays a direct role in the translocation of protons across the membrane
DSUI_RS04120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSUI_RS04125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSUI_RS04130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSUI_RS04135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSUI_RS04140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSUI_RS04145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSUI_RS04160	COG2226	methyltransferase
DSUI_RS04170	COG0745	RESPONSE REGULATOR receiver
DSUI_RS04215	COG0708	Exodeoxyribonuclease III
DSUI_RS04220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSUI_RS04240	COG0348	domain, Protein
DSUI_RS04270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSUI_RS04275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSUI_RS04285	COG0154	amidase activity
DSUI_RS04290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSUI_RS04295	COG1077	Cell shape determining protein MreB Mrl
DSUI_RS04300	COG1792	Involved in formation and maintenance of cell shape
DSUI_RS04305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DSUI_RS04310	COG0768	penicillin binding
DSUI_RS04315	COG0772	Belongs to the SEDS family
DSUI_RS04350	COG1686	Belongs to the peptidase S11 family
DSUI_RS04355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSUI_RS04360	COG2921	Belongs to the UPF0250 family
DSUI_RS04365	COG0321	lipoyl(octanoyl) transferase activity
DSUI_RS04370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DSUI_RS04420	COG3437	response regulator, receiver
DSUI_RS04455	COG0114	fumarate hydratase activity
DSUI_RS04465	COG0348	domain, Protein
DSUI_RS04475	COG2204	response regulator
DSUI_RS04490	COG0210	DNA helicase
DSUI_RS04500	COG3245	cytochrome
DSUI_RS04545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSUI_RS04550	COG0316	Belongs to the HesB IscA family
DSUI_RS04575	COG2030	dehydratase
DSUI_RS04600	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DSUI_RS04610	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DSUI_RS04635	COG0826	peptidase U32
DSUI_RS04640	COG0826	peptidase U32
DSUI_RS04645	COG3154	lipid carrier protein
DSUI_RS04650	COG1285	pathogenesis
DSUI_RS04665	COG1515	deoxyribonuclease V activity
DSUI_RS04680	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSUI_RS04700	COG1960	acyl-CoA dehydrogenase activity
DSUI_RS04705	COG0183	Belongs to the thiolase family
DSUI_RS04710	COG1960	acyl-CoA dehydrogenase activity
DSUI_RS04725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSUI_RS04730	COG1024	Enoyl-CoA hydratase
DSUI_RS04740	COG5001	Diguanylate cyclase
DSUI_RS04760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSUI_RS04770	COG1473	amidohydrolase
DSUI_RS04775	COG1660	Displays ATPase and GTPase activities
DSUI_RS04810	COG0840	transmembrane signaling receptor activity
DSUI_RS04810	COG3290	protein histidine kinase activity
DSUI_RS04815	COG1194	a g-specific adenine glycosylase
DSUI_RS04820	COG0714	Associated with various cellular activities
DSUI_RS04840	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DSUI_RS04845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DSUI_RS04855	COG0583	DNA-binding transcription factor activity
DSUI_RS04895	COG2022	thiamine diphosphate biosynthetic process
DSUI_RS04905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSUI_RS04935	COG2177	Part of the ABC transporter FtsEX involved in
DSUI_RS04940	COG2884	Cell division ATP-binding protein ftsE
DSUI_RS04950	COG0612	Peptidase, M16
DSUI_RS04955	COG0612	Peptidase, M16
DSUI_RS04960	COG0742	ribosomal rna small subunit methyltransferase
DSUI_RS04965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DSUI_RS04970	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSUI_RS04975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DSUI_RS04980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DSUI_RS04995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSUI_RS05005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSUI_RS05010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DSUI_RS05015	COG0193	aminoacyl-tRNA hydrolase activity
DSUI_RS05020	COG0012	GTP binding
DSUI_RS05025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSUI_RS05030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSUI_RS05035	COG3568	Endonuclease Exonuclease Phosphatase
DSUI_RS05040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSUI_RS05065	COG0174	glutamine synthetase
DSUI_RS05075	COG3852	Histidine kinase
DSUI_RS05080	COG2204	response regulator
DSUI_RS05085	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DSUI_RS05085	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DSUI_RS05090	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSUI_RS05095	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DSUI_RS05105	COG0237	dephospho-CoA kinase activity
DSUI_RS05110	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DSUI_RS05115	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DSUI_RS05120	COG0352	thiamine-phosphate diphosphorylase activity
DSUI_RS05130	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DSUI_RS05135	COG0004	ammonium transporteR
DSUI_RS05145	COG2217	Heavy metal translocating P-type atpase
DSUI_RS05180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS05185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSUI_RS05260	COG0840	transmembrane signaling receptor activity
DSUI_RS05270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSUI_RS05280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DSUI_RS05285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSUI_RS05290	COG0067	glutamate synthase
DSUI_RS05290	COG0069	glutamate synthase activity
DSUI_RS05290	COG0070	glutamate synthase
DSUI_RS05305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSUI_RS05315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSUI_RS05335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSUI_RS05335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSUI_RS05335	COG1703	isobutyryl-CoA mutase activity
DSUI_RS05350	COG1022	Amp-dependent synthetase and ligase
DSUI_RS05385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSUI_RS05390	COG0840	transmembrane signaling receptor activity
DSUI_RS05395	COG2703	oxygen carrier activity
DSUI_RS05405	COG0386	Belongs to the glutathione peroxidase family
DSUI_RS05410	COG1999	signal sequence binding
DSUI_RS05420	COG0129	dihydroxy-acid dehydratase activity
DSUI_RS05430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSUI_RS05475	COG2814	Major facilitator Superfamily
DSUI_RS05545	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DSUI_RS05560	COG0501	Belongs to the peptidase M48B family
DSUI_RS05570	COG0583	DNA-binding transcription factor activity
DSUI_RS05585	COG2204	response regulator
DSUI_RS05590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSUI_RS05590	COG1024	Enoyl-CoA hydratase
DSUI_RS05600	COG0309	Hydrogenase expression formation protein (HypE)
DSUI_RS05605	COG0409	Hydrogenase expression formation protein
DSUI_RS05610	COG0298	carbon dioxide binding
DSUI_RS05620	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DSUI_RS05635	COG0375	protein maturation
DSUI_RS05645	COG1858	cytochrome C peroxidase
DSUI_RS05650	COG4133	protoheme IX ABC transporter activity
DSUI_RS05655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSUI_RS05665	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSUI_RS05670	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DSUI_RS05680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSUI_RS05715	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DSUI_RS05720	COG4191	Histidine kinase
DSUI_RS05725	COG0019	diaminopimelate decarboxylase activity
DSUI_RS05730	COG1965	Belongs to the frataxin family
DSUI_RS05735	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DSUI_RS05780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSUI_RS05785	COG1702	phosphate starvation-inducible protein PhoH
DSUI_RS05790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DSUI_RS05795	COG4535	Mg2 and Co2 transporter CorC
DSUI_RS05800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSUI_RS05805	COG0752	glycyl-tRNA synthetase alpha subunit
DSUI_RS05810	COG0751	glycine-tRNA ligase activity
DSUI_RS05815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSUI_RS05870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSUI_RS05875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSUI_RS05880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DSUI_RS05890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSUI_RS05895	COG4974	Belongs to the 'phage' integrase family
DSUI_RS05910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSUI_RS05920	COG1466	dna polymerase III delta subunit
DSUI_RS05930	COG0495	leucyl-tRNA aminoacylation
DSUI_RS05945	COG0210	DNA helicase
DSUI_RS05970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSUI_RS05975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSUI_RS05980	COG0312	modulator of DNA gyrase
DSUI_RS05985	COG3028	Belongs to the UPF0307 family
DSUI_RS05990	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSUI_RS06000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DSUI_RS06005	COG0166	Belongs to the GPI family
DSUI_RS06040	COG0717	Belongs to the dCTP deaminase family
DSUI_RS06045	COG0489	protein tyrosine kinase activity
DSUI_RS06050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSUI_RS06050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSUI_RS06060	COG0659	secondary active sulfate transmembrane transporter activity
DSUI_RS06065	COG1254	Belongs to the acylphosphatase family
DSUI_RS06075	COG0450	alkyl hydroperoxide reductase
DSUI_RS06080	COG4771	TonB-dependent receptor
DSUI_RS06100	COG0583	DNA-binding transcription factor activity
DSUI_RS06105	COG1741	Belongs to the pirin family
DSUI_RS06115	COG0745	RESPONSE REGULATOR receiver
DSUI_RS06135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSUI_RS06140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSUI_RS06145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSUI_RS06145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSUI_RS06150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSUI_RS06160	COG0793	Belongs to the peptidase S41A family
DSUI_RS06165	COG4942	peptidase
DSUI_RS06175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSUI_RS06185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DSUI_RS06195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSUI_RS06200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSUI_RS06205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS06210	COG1459	type II secretion system
DSUI_RS06220	COG2165	general secretion pathway protein
DSUI_RS06225	COG2165	general secretion pathway protein
DSUI_RS06280	COG1450	Type ii and iii secretion system protein
DSUI_RS06285	COG3267	Type II secretory pathway component ExeA
DSUI_RS06285	COG3409	Peptidoglycan-binding domain 1 protein
DSUI_RS06300	COG3307	-O-antigen
DSUI_RS06310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSUI_RS06315	COG2226	methyltransferase
DSUI_RS06320	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DSUI_RS06325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSUI_RS06335	COG1595	DNA-templated transcription, initiation
DSUI_RS06350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSUI_RS06370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSUI_RS06375	COG0071	Belongs to the small heat shock protein (HSP20) family
DSUI_RS06385	COG0494	nUDIX hydrolase
DSUI_RS06400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSUI_RS06415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DSUI_RS06430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSUI_RS06435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSUI_RS06440	COG0741	lytic transglycosylase activity
DSUI_RS06445	COG0442	prolyl-tRNA aminoacylation
DSUI_RS06450	COG0494	nUDIX hydrolase
DSUI_RS06465	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DSUI_RS06470	COG1765	OsmC-like protein
DSUI_RS06475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSUI_RS06480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSUI_RS06490	COG0316	Belongs to the HesB IscA family
DSUI_RS06495	COG4942	peptidase
DSUI_RS06495	COG1388	LysM domain
DSUI_RS06525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSUI_RS06535	COG0596	Alpha beta hydrolase
DSUI_RS06545	COG0598	Magnesium transport protein CorA
DSUI_RS06550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DSUI_RS06560	COG2703	oxygen carrier activity
DSUI_RS06575	COG0513	Belongs to the DEAD box helicase family
DSUI_RS06580	COG2030	dehydratase
DSUI_RS06590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSUI_RS06605	COG0739	heme binding
DSUI_RS06610	COG0284	orotidine-5'-phosphate decarboxylase activity
DSUI_RS06620	COG3447	MASE1 domain protein
DSUI_RS06620	COG5001	Diguanylate cyclase
DSUI_RS06620	COG5002	protein histidine kinase activity
DSUI_RS06635	COG3850	Histidine kinase
DSUI_RS06645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSUI_RS06650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DSUI_RS06670	COG0583	DNA-binding transcription factor activity
DSUI_RS06675	COG0840	transmembrane signaling receptor activity
DSUI_RS06680	COG1643	Atp-dependent helicase
DSUI_RS06705	COG1024	Enoyl-CoA hydratase
DSUI_RS06710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DSUI_RS06720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DSUI_RS06785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS06800	COG3267	Type II secretory pathway component ExeA
DSUI_RS06800	COG3409	Peptidoglycan-binding domain 1 protein
DSUI_RS06805	COG2204	response regulator
DSUI_RS06810	COG1127	ABC transporter
DSUI_RS06815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSUI_RS06820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSUI_RS06825	COG2853	Lipoprotein
DSUI_RS06835	COG3113	response to antibiotic
DSUI_RS06840	COG1131	(ABC) transporter
DSUI_RS06845	COG0842	Transport permease protein
DSUI_RS06850	COG5007	Belongs to the BolA IbaG family
DSUI_RS06855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSUI_RS06870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSUI_RS06875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSUI_RS06890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSUI_RS06895	COG0131	Imidazoleglycerol-phosphate dehydratase
DSUI_RS06900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSUI_RS06905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSUI_RS06910	COG0107	imidazoleglycerol-phosphate synthase activity
DSUI_RS06915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSUI_RS06920	COG0140	phosphoribosyl-ATP diphosphatase activity
DSUI_RS06930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSUI_RS06935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSUI_RS06945	COG0121	glutamine amidotransferase
DSUI_RS06950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSUI_RS06955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DSUI_RS06970	COG2203	Gaf domain
DSUI_RS06970	COG3706	GGDEF domain
DSUI_RS06970	COG4251	negative regulation of phosphorylation
DSUI_RS06970	COG5001	Diguanylate cyclase
DSUI_RS06980	COG2201	protein-glutamate methylesterase activity
DSUI_RS06985	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSUI_RS06990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSUI_RS06995	COG0835	chemotaxis
DSUI_RS07000	COG0840	transmembrane signaling receptor activity
DSUI_RS07005	COG2198	Histidine kinase
DSUI_RS07005	COG0643	Histidine kinase
DSUI_RS07020	COG0745	RESPONSE REGULATOR receiver
DSUI_RS07030	COG0534	Mate efflux family protein
DSUI_RS07045	COG0045	succinate-CoA ligase (ADP-forming) activity
DSUI_RS07050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSUI_RS07055	COG0861	Integral membrane protein TerC family
DSUI_RS07065	COG0515	serine threonine protein kinase
DSUI_RS07065	COG2815	serine threonine protein kinase
DSUI_RS07070	COG0631	protein serine/threonine phosphatase activity
DSUI_RS07090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS07095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS07125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS07130	COG1136	(ABC) transporter
DSUI_RS07135	COG3284	Transcriptional regulator
DSUI_RS07140	COG1012	belongs to the aldehyde dehydrogenase family
DSUI_RS07155	COG0577	efflux transmembrane transporter activity
DSUI_RS07155	COG1136	(ABC) transporter
DSUI_RS07165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DSUI_RS07170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSUI_RS07175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSUI_RS07180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSUI_RS07185	COG0840	transmembrane signaling receptor activity
DSUI_RS07265	COG0071	Belongs to the small heat shock protein (HSP20) family
DSUI_RS07270	COG0542	response to heat
DSUI_RS07280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSUI_RS07325	COG0501	Belongs to the peptidase M48B family
DSUI_RS07330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSUI_RS07360	COG2826	transposase and inactivated derivatives, IS30 family
DSUI_RS07375	COG0617	tRNA 3'-terminal CCA addition
DSUI_RS07390	COG0628	permease
DSUI_RS07395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSUI_RS07400	COG4654	Cytochrome c, class I
DSUI_RS07415	COG2814	Major facilitator Superfamily
DSUI_RS07425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DSUI_RS07440	COG2205	protein histidine kinase activity
DSUI_RS07445	COG0745	RESPONSE REGULATOR receiver
DSUI_RS07465	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSUI_RS07470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSUI_RS07475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSUI_RS07485	COG2003	Belongs to the UPF0758 family
DSUI_RS07490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSUI_RS07495	COG0756	dUTP diphosphatase activity
DSUI_RS07500	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSUI_RS07510	COG3264	Mechanosensitive ion channel
DSUI_RS07510	COG1196	nuclear chromosome segregation
DSUI_RS07515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSUI_RS07515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSUI_RS07525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSUI_RS07535	COG0586	Pfam SNARE associated Golgi protein
DSUI_RS07540	COG0784	Response regulator, receiver
DSUI_RS07550	COG5001	Diguanylate cyclase
DSUI_RS07555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSUI_RS07560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSUI_RS07575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSUI_RS07585	COG0126	phosphoglycerate kinase activity
DSUI_RS07590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSUI_RS07600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSUI_RS07605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSUI_RS07615	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DSUI_RS07625	COG5001	Diguanylate cyclase
DSUI_RS07625	COG5002	protein histidine kinase activity
DSUI_RS07640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSUI_RS07650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSUI_RS07650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DSUI_RS07655	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DSUI_RS07670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DSUI_RS07680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSUI_RS07685	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSUI_RS07690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DSUI_RS07705	COG4566	intracellular signal transduction
DSUI_RS07710	COG0247	lactate metabolic process
DSUI_RS07715	COG1139	Iron-sulfur cluster binding protein
DSUI_RS07720	COG1556	Lactate utilization protein
DSUI_RS07725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DSUI_RS07730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSUI_RS07735	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DSUI_RS07755	COG0006	proline dipeptidase activity
DSUI_RS07760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSUI_RS07780	COG0151	Belongs to the GarS family
DSUI_RS07785	COG0408	coproporphyrinogen oxidase activity
DSUI_RS07800	COG2959	enzyme of heme biosynthesis
DSUI_RS07810	COG0181	hydroxymethylbilane synthase activity
DSUI_RS07815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DSUI_RS07825	COG0318	PFAM AMP-dependent synthetase and ligase
DSUI_RS07830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSUI_RS07890	COG0745	RESPONSE REGULATOR receiver
DSUI_RS07895	COG0642	Histidine kinase
DSUI_RS07900	COG2194	sulfuric ester hydrolase activity
DSUI_RS07910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DSUI_RS07930	COG2217	Heavy metal translocating P-type atpase
DSUI_RS07940	COG3278	Belongs to the heme-copper respiratory oxidase family
DSUI_RS07975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSUI_RS07980	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSUI_RS08025	COG3945	hemerythrin HHE cation binding domain
DSUI_RS08030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS08035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSUI_RS08050	COG2217	Heavy metal translocating P-type atpase
DSUI_RS08065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DSUI_RS08065	COG1918	ferrous iron import across plasma membrane
DSUI_RS08075	COG0672	)-iron permease
DSUI_RS08080	COG4633	Protein conserved in bacteria
DSUI_RS08130	COG3128	pkhd-type hydroxylase
DSUI_RS08135	COG4774	siderophore transport
DSUI_RS08145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSUI_RS08150	COG1858	cytochrome C peroxidase
DSUI_RS08155	COG4771	TonB-dependent receptor
DSUI_RS08185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSUI_RS08195	COG1429	ligase activity, forming nitrogen-metal bonds
DSUI_RS08200	COG4771	TonB-dependent receptor
DSUI_RS08225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSUI_RS08230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSUI_RS08230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSUI_RS08235	COG0347	Belongs to the P(II) protein family
DSUI_RS08245	COG0492	ferredoxin-NADP+ reductase activity
DSUI_RS08255	COG1674	ftsk spoiiie
DSUI_RS08260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DSUI_RS08265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSUI_RS08275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSUI_RS08280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSUI_RS08315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSUI_RS08320	COG1360	Flagellar Motor Protein
DSUI_RS08330	COG0745	RESPONSE REGULATOR receiver
DSUI_RS08335	COG0643	Histidine kinase
DSUI_RS08335	COG2198	Histidine kinase
DSUI_RS08340	COG0835	chemotaxis
DSUI_RS08345	COG0840	transmembrane signaling receptor activity
DSUI_RS08345	COG0840	transmembrane signaling receptor activity
DSUI_RS08350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSUI_RS08355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSUI_RS08360	COG2201	protein-glutamate methylesterase activity
DSUI_RS08375	COG0840	transmembrane signaling receptor activity
DSUI_RS08380	COG0784	Response regulator, receiver
DSUI_RS08380	COG0835	chemotaxis
DSUI_RS08385	COG0784	Response regulator, receiver
DSUI_RS08385	COG0835	chemotaxis
DSUI_RS08395	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DSUI_RS08400	COG2198	Histidine kinase
DSUI_RS08400	COG0784	Response regulator, receiver
DSUI_RS08400	COG0643	Histidine kinase
DSUI_RS08430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSUI_RS08455	COG1815	bacterial-type flagellum-dependent cell motility
DSUI_RS08460	COG1558	bacterial-type flagellum-dependent cell motility
DSUI_RS08465	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSUI_RS08475	COG4787	bacterial-type flagellum-dependent cell motility
DSUI_RS08485	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DSUI_RS08490	COG1706	bacterial-type flagellum-dependent cell motility
DSUI_RS08495	COG1705	Flagellar rod assembly protein muramidase FlgJ
DSUI_RS08495	COG3951	Flagellar rod assembly protein muramidase FlgJ
DSUI_RS08505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSUI_RS08525	COG1338	Plays a role in the flagellum-specific transport system
DSUI_RS08530	COG3190	flagellar
DSUI_RS08535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSUI_RS08540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSUI_RS08560	COG1157	protein secretion by the type III secretion system
DSUI_RS08580	COG0784	Response regulator, receiver
DSUI_RS08580	COG2205	protein histidine kinase activity
DSUI_RS08590	COG1677	Flagellar hook-basal body complex protein FliE
DSUI_RS08630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSUI_RS08675	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DSUI_RS08680	COG2257	FlhB HrpN YscU SpaS Family
DSUI_RS08705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSUI_RS08710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSUI_RS08725	COG0438	transferase activity, transferring glycosyl groups
DSUI_RS08725	COG1216	Glycosyl transferase, family 2
DSUI_RS08775	COG1414	Transcriptional regulator
DSUI_RS08815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DSUI_RS08820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DSUI_RS08825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSUI_RS08830	COG0723	plastoquinol--plastocyanin reductase activity
DSUI_RS08835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSUI_RS08840	COG2857	Cytochrome c1
DSUI_RS08845	COG0625	glutathione transferase activity
DSUI_RS08850	COG2969	positive regulation of protein catabolic process
DSUI_RS08855	COG0243	molybdopterin cofactor binding
DSUI_RS08860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSUI_RS08865	COG1942	4-Oxalocrotonate Tautomerase
DSUI_RS08895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSUI_RS08910	COG3707	response regulator
DSUI_RS08925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSUI_RS08935	COG1116	anion transmembrane transporter activity
DSUI_RS08945	COG0438	transferase activity, transferring glycosyl groups
DSUI_RS08995	COG0306	phosphate transporter
DSUI_RS09000	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
DSUI_RS09010	COG0798	PFAM Bile acid sodium symporter
DSUI_RS09015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSUI_RS09025	COG2205	protein histidine kinase activity
DSUI_RS09030	COG0745	RESPONSE REGULATOR receiver
DSUI_RS09050	COG1942	4-Oxalocrotonate Tautomerase
DSUI_RS09060	COG0583	DNA-binding transcription factor activity
DSUI_RS09070	COG0840	transmembrane signaling receptor activity
DSUI_RS09095	COG5002	protein histidine kinase activity
DSUI_RS09095	COG0784	Response regulator, receiver
DSUI_RS09095	COG2205	protein histidine kinase activity
DSUI_RS09100	COG0745	RESPONSE REGULATOR receiver
DSUI_RS09105	COG3437	response regulator, receiver
DSUI_RS09105	COG2205	protein histidine kinase activity
DSUI_RS09105	COG3850	Histidine kinase
DSUI_RS09105	COG4999	Histidine kinase
DSUI_RS09120	COG1538	Outer membrane efflux protein
DSUI_RS09140	COG1742	UPF0060 membrane protein
DSUI_RS09145	COG1309	transcriptional regulator
DSUI_RS09150	COG1902	pentaerythritol trinitrate reductase activity
DSUI_RS09155	COG0697	spore germination
DSUI_RS09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSUI_RS09180	COG0488	(ABC) transporter
DSUI_RS09185	COG5002	protein histidine kinase activity
DSUI_RS09190	COG2204	response regulator
DSUI_RS09205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSUI_RS09205	COG1418	mRNA catabolic process
DSUI_RS09220	COG4948	Mandelate Racemase Muconate Lactonizing
DSUI_RS09225	COG0583	DNA-binding transcription factor activity
DSUI_RS09240	COG1704	LemA family
DSUI_RS09245	COG2814	Major facilitator Superfamily
DSUI_RS09255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSUI_RS09275	COG1448	Aminotransferase
DSUI_RS09285	COG1811	Na channel or pump
DSUI_RS09290	COG0583	DNA-binding transcription factor activity
DSUI_RS09295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSUI_RS09310	COG1475	DNA binding
DSUI_RS09315	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DSUI_RS09335	COG1294	oxidase, subunit
DSUI_RS09345	COG1944	ATP diphosphatase activity
DSUI_RS09350	COG1429	ligase activity, forming nitrogen-metal bonds
DSUI_RS09365	COG4771	TonB-dependent receptor
DSUI_RS09370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSUI_RS09375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSUI_RS09375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSUI_RS09380	COG0028	Belongs to the TPP enzyme family
DSUI_RS09385	COG0440	acetolactate synthase activity
DSUI_RS09415	COG0546	phosphoglycolate phosphatase activity
DSUI_RS09420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSUI_RS09430	COG0402	S-adenosylhomocysteine deaminase activity
DSUI_RS09445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSUI_RS09460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSUI_RS09470	COG0776	regulation of translation
DSUI_RS09480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DSUI_RS09510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DSUI_RS09515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSUI_RS09540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSUI_RS09545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DSUI_RS09550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSUI_RS09555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSUI_RS09560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSUI_RS09565	COG0072	phenylalanine-tRNA ligase activity
DSUI_RS09565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSUI_RS09570	COG0776	regulation of translation
DSUI_RS09590	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DSUI_RS09595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSUI_RS09610	COG2951	lytic endotransglycosylase activity
DSUI_RS09625	COG0714	Associated with various cellular activities
DSUI_RS09630	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSUI_RS09635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSUI_RS09640	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DSUI_RS09660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSUI_RS09665	COG2895	sulfate adenylyltransferase (ATP) activity
DSUI_RS09675	COG0175	sulfate reduction
DSUI_RS09690	COG0730	response to heat
DSUI_RS09695	COG0583	DNA-binding transcription factor activity
DSUI_RS09700	COG0360	Binds together with S18 to 16S ribosomal RNA
DSUI_RS09705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSUI_RS09710	COG0359	binds to the 23S rRNA
DSUI_RS09715	COG0305	Participates in initiation and elongation during chromosome replication
DSUI_RS09730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DSUI_RS09735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSUI_RS09745	COG0251	oxidation-reduction process
DSUI_RS09765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSUI_RS09770	COG0517	IMP dehydrogenase activity
DSUI_RS09770	COG0516	GMP reductase activity
DSUI_RS09775	COG2176	DNA-directed DNA polymerase activity
DSUI_RS09780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSUI_RS09825	COG0194	GDP metabolic process
DSUI_RS09840	COG0583	DNA-binding transcription factor activity
DSUI_RS09845	COG0657	acetylesterase activity
DSUI_RS09850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS09860	COG1538	Outer membrane efflux protein
DSUI_RS09865	COG2827	Endonuclease containing a URI domain
DSUI_RS09890	COG0583	DNA-binding transcription factor activity
DSUI_RS09895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DSUI_RS09900	COG0583	DNA-binding transcription factor activity
DSUI_RS09925	COG1832	CoA-binding protein
DSUI_RS09930	COG1024	Enoyl-CoA hydratase
DSUI_RS09935	COG0626	cystathionine gamma-synthase activity
DSUI_RS09940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DSUI_RS09965	COG0488	(ABC) transporter
DSUI_RS09970	COG4178	(ABC) transporter
DSUI_RS09985	COG1403	HNH endonuclease
DSUI_RS10025	COG0683	leucine binding
DSUI_RS10030	COG0545	Peptidyl-prolyl cis-trans isomerase
DSUI_RS10055	COG2011	ABC-type metal ion transport system permease component
DSUI_RS10060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DSUI_RS10075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DSUI_RS10095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSUI_RS10110	COG4654	Cytochrome c, class I
DSUI_RS10115	COG4191	Histidine kinase
DSUI_RS10120	COG4566	intracellular signal transduction
DSUI_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSUI_RS10130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DSUI_RS10150	COG2863	cytochrome
DSUI_RS10155	COG3258	Cytochrome c
DSUI_RS10165	COG0583	DNA-binding transcription factor activity
DSUI_RS10200	COG1408	metallophosphoesterase
DSUI_RS10210	COG1595	DNA-templated transcription, initiation
DSUI_RS10270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSUI_RS10275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS10280	COG1045	serine acetyltransferase
DSUI_RS10290	COG0583	DNA-binding transcription factor activity
DSUI_RS10295	COG1979	alcohol dehydrogenase
DSUI_RS10300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSUI_RS10320	COG1116	anion transmembrane transporter activity
DSUI_RS10325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSUI_RS10330	COG2199	diguanylate cyclase activity
DSUI_RS10330	COG2200	EAL domain
DSUI_RS10330	COG3287	FIST C domain
DSUI_RS10335	COG0840	transmembrane signaling receptor activity
DSUI_RS10345	COG0686	Belongs to the AlaDH PNT family
DSUI_RS10360	COG0776	regulation of translation
DSUI_RS10385	COG0527	aspartate kinase activity
DSUI_RS10400	COG0720	synthase
DSUI_RS10445	COG0776	regulation of translation
DSUI_RS10450	COG2974	May be involved in recombination
DSUI_RS10460	COG1199	ATP-dependent helicase activity
DSUI_RS10470	COG1763	Mo-molybdopterin cofactor biosynthetic process
DSUI_RS10475	COG0303	'Molybdopterin
DSUI_RS10480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DSUI_RS10485	COG0314	molybdopterin synthase activity
DSUI_RS10505	COG2197	response regulator
DSUI_RS10510	COG0840	transmembrane signaling receptor activity
DSUI_RS10520	COG0542	response to heat
DSUI_RS10530	COG0727	PFAM Uncharacterised protein family (UPF0153)
DSUI_RS10555	COG2819	hydrolase of the alpha beta superfamily
DSUI_RS10575	COG1846	Transcriptional regulator
DSUI_RS10580	COG1764	response to oxidative stress
DSUI_RS10610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DSUI_RS10640	COG2818	Glycosylase
DSUI_RS10650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSUI_RS10675	COG1562	ergosterol biosynthetic process
DSUI_RS10680	COG1562	ergosterol biosynthetic process
DSUI_RS10690	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSUI_RS10695	COG0740	serine-type endopeptidase activity
DSUI_RS10700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSUI_RS10705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSUI_RS10725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSUI_RS10760	COG0039	L-malate dehydrogenase activity
DSUI_RS10770	COG2009	succinate dehydrogenase
DSUI_RS10780	COG1053	succinate dehydrogenase
DSUI_RS10790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DSUI_RS10800	COG0567	Dehydrogenase, E1 component
DSUI_RS10805	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSUI_RS10810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSUI_RS10820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DSUI_RS10830	COG1067	ATP-dependent peptidase activity
DSUI_RS10835	COG2832	Protein of unknown function (DUF454)
DSUI_RS10845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSUI_RS10855	COG0583	DNA-binding transcription factor activity
DSUI_RS10890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSUI_RS10895	COG0601	transmembrane transport
DSUI_RS10900	COG0747	negative chemotaxis
DSUI_RS10905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSUI_RS10910	COG0784	Response regulator, receiver
DSUI_RS10910	COG2205	protein histidine kinase activity
DSUI_RS10910	COG5002	protein histidine kinase activity
DSUI_RS10930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSUI_RS10960	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSUI_RS10975	COG3135	benzoate transporter
DSUI_RS10995	COG0583	DNA-binding transcription factor activity
DSUI_RS11025	COG0587	DNA-directed DNA polymerase activity
DSUI_RS11045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSUI_RS11075	COG3655	Transcriptional regulator
DSUI_RS11135	COG0308	aminopeptidase N
DSUI_RS11145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSUI_RS11145	COG3008	intermembrane lipid transfer
DSUI_RS11150	COG2995	paraquat-inducible protein a
DSUI_RS11165	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSUI_RS11180	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSUI_RS11185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSUI_RS11205	COG2200	EAL domain
DSUI_RS11210	COG1960	acyl-CoA dehydrogenase activity
DSUI_RS11230	COG1309	transcriptional regulator
DSUI_RS11235	COG4181	ATPase activity
DSUI_RS11245	COG0709	Synthesizes selenophosphate from selenide and ATP
DSUI_RS11250	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DSUI_RS11255	COG1335	isochorismatase
DSUI_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
DSUI_RS11265	COG0504	CTP synthase activity
DSUI_RS11270	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DSUI_RS11285	COG0148	phosphopyruvate hydratase activity
DSUI_RS11290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DSUI_RS11310	COG3022	response to hydroperoxide
DSUI_RS11325	COG3012	SEC-C Motif Domain Protein
DSUI_RS11350	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSUI_RS11365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DSUI_RS11370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSUI_RS11390	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSUI_RS11395	COG0842	Transport permease protein
DSUI_RS11400	COG1131	(ABC) transporter
DSUI_RS11415	COG2501	S4 domain
DSUI_RS11425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DSUI_RS11435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSUI_RS11440	COG0789	Transcriptional regulator
DSUI_RS11455	COG0583	DNA-binding transcription factor activity
DSUI_RS11460	COG3384	dioxygenase
DSUI_RS11465	COG3038	cytochrome b561
DSUI_RS11475	COG2353	YceI-like domain
DSUI_RS11480	COG2205	protein histidine kinase activity
DSUI_RS11490	COG2204	response regulator
DSUI_RS11520	COG0483	inositol monophosphate 1-phosphatase activity
DSUI_RS11540	COG1104	cysteine desulfurase activity
DSUI_RS11545	COG1104	cysteine desulfurase activity
DSUI_RS11550	COG0822	iron-sulfur transferase activity
DSUI_RS11560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSUI_RS11565	COG0443	Heat shock 70 kDa protein
DSUI_RS11585	COG0560	Phosphoserine phosphatase
DSUI_RS11590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DSUI_RS11595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSUI_RS11615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSUI_RS11630	COG1355	regulation of microtubule-based process
DSUI_RS11640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSUI_RS11645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DSUI_RS11710	COG0456	acetyltransferase
DSUI_RS11715	COG1573	uracil-dna glycosylase
DSUI_RS11720	COG1704	LemA family
DSUI_RS11725	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DSUI_RS11735	COG0477	Major facilitator Superfamily
DSUI_RS11740	COG0583	DNA-binding transcription factor activity
DSUI_RS11745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSUI_RS11770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DSUI_RS11790	COG1032	radical SAM domain protein
DSUI_RS11795	COG2200	EAL domain
DSUI_RS11795	COG3287	FIST C domain
DSUI_RS11795	COG2199	diguanylate cyclase activity
DSUI_RS11805	COG1217	gtp-binding protein TYPA
DSUI_RS11820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSUI_RS11855	COG0556	nucleotide-excision repair
DSUI_RS11860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSUI_RS11865	COG1530	ribonuclease E activity
DSUI_RS11885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DSUI_RS11885	COG0616	signal peptide processing
DSUI_RS11890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSUI_RS11895	COG0424	maF-like protein
DSUI_RS11905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSUI_RS11910	COG0416	fatty acid biosynthetic process
DSUI_RS11915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSUI_RS11930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSUI_RS11935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSUI_RS11945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSUI_RS11950	COG1595	DNA-templated transcription, initiation
DSUI_RS11955	COG3086	response to oxidative stress
DSUI_RS11960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSUI_RS11970	COG0481	GTPase activity
DSUI_RS11975	COG0681	Belongs to the peptidase S26 family
DSUI_RS11985	COG0571	ribonuclease III activity
DSUI_RS11990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSUI_RS11995	COG1381	Involved in DNA repair and RecF pathway recombination
DSUI_RS12000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSUI_RS12005	COG0736	holo-[acyl-carrier-protein] synthase activity
DSUI_RS12010	COG1472	Belongs to the glycosyl hydrolase 3 family
DSUI_RS12015	COG1793	dna ligase
DSUI_RS12020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSUI_RS12035	COG0322	excinuclease ABC activity
DSUI_RS12090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DSUI_RS12095	COG0328	RNA-DNA hybrid ribonuclease activity
DSUI_RS12100	COG2226	methyltransferase
DSUI_RS12105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSUI_RS12110	COG2201	protein-glutamate methylesterase activity
DSUI_RS12115	COG5001	Diguanylate cyclase
DSUI_RS12115	COG2203	Gaf domain
DSUI_RS12115	COG4251	negative regulation of phosphorylation
DSUI_RS12115	COG3706	GGDEF domain
DSUI_RS12135	COG2815	serine threonine protein kinase
DSUI_RS12135	COG0515	serine threonine protein kinase
DSUI_RS12145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSUI_RS12175	COG0789	Transcriptional regulator
DSUI_RS12185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSUI_RS12215	COG2826	transposase and inactivated derivatives, IS30 family
DSUI_RS12240	COG4566	intracellular signal transduction
DSUI_RS12245	COG4191	Histidine kinase
DSUI_RS12250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSUI_RS12290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DSUI_RS12310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSUI_RS12320	COG0515	serine threonine protein kinase
DSUI_RS12320	COG2815	serine threonine protein kinase
DSUI_RS12330	COG0564	pseudouridine synthase activity
DSUI_RS12340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSUI_RS12345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSUI_RS12365	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSUI_RS12380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSUI_RS12385	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSUI_RS12390	COG0277	FAD linked oxidase domain protein
DSUI_RS12400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DSUI_RS12405	COG1393	Belongs to the ArsC family
DSUI_RS12410	COG2183	response to ionizing radiation
DSUI_RS12415	COG3300	MHYT domain
DSUI_RS12415	COG5001	Diguanylate cyclase
DSUI_RS12420	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DSUI_RS12650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS12665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS12725	COG5001	Diguanylate cyclase
DSUI_RS12725	COG3300	MHYT domain
DSUI_RS12785	COG2974	May be involved in recombination
DSUI_RS12805	COG2894	cell division
DSUI_RS12850	COG1815	bacterial-type flagellum-dependent cell motility
DSUI_RS12885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSUI_RS12890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS12935	COG5002	protein histidine kinase activity
DSUI_RS12955	COG4644	lycopene metabolic process
DSUI_RS12965	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSUI_RS12975	COG0084	hydrolase, TatD family'
DSUI_RS12990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSUI_RS12995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSUI_RS13010	COG1278	Cold shock
DSUI_RS13040	COG0702	epimerase
DSUI_RS13045	COG1733	regulation of RNA biosynthetic process
DSUI_RS13065	COG0519	Catalyzes the synthesis of GMP from XMP
DSUI_RS13065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSUI_RS13080	COG2914	Belongs to the UPF0125 (RnfH) family
DSUI_RS13085	COG2867	negative regulation of translational initiation
DSUI_RS13090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSUI_RS13095	COG2860	membrane
DSUI_RS13105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DSUI_RS13110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSUI_RS13115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSUI_RS13120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSUI_RS13125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSUI_RS13130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSUI_RS13135	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSUI_RS13155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DSUI_RS13160	COG0575	Belongs to the CDS family
DSUI_RS13165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSUI_RS13170	COG0233	cytoplasmic translational termination
DSUI_RS13175	COG0528	UMP kinase activity
DSUI_RS13180	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DSUI_RS13185	COG0052	Belongs to the universal ribosomal protein uS2 family
DSUI_RS13195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DSUI_RS13200	COG0242	peptide deformylase activity
DSUI_RS13210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSUI_RS13215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSUI_RS13220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSUI_RS13235	COG3012	SEC-C Motif Domain Protein
DSUI_RS13235	COG3318	Belongs to the UPF0149 family
DSUI_RS13240	COG2252	PERMEase
DSUI_RS13245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DSUI_RS13255	COG0436	Aminotransferase
DSUI_RS13260	COG2171	N-acyltransferase activity
DSUI_RS13270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSUI_RS13280	COG0330	HflC and HflK could
DSUI_RS13300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSUI_RS13305	COG1185	polyribonucleotide nucleotidyltransferase activity
DSUI_RS13310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSUI_RS13315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSUI_RS13320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DSUI_RS13325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSUI_RS13330	COG2251	uridine kinase activity
DSUI_RS13330	COG0195	Participates in both transcription termination and antitermination
DSUI_RS13335	COG0779	Required for maturation of 30S ribosomal subunits
DSUI_RS13340	COG1187	pseudouridine synthase activity
DSUI_RS13345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSUI_RS13350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DSUI_RS13355	COG0180	Tryptophanyl-tRNA synthetase
DSUI_RS13360	COG1994	Peptidase M50
DSUI_RS13365	COG0009	L-threonylcarbamoyladenylate synthase
DSUI_RS13370	COG0613	PHP domain protein
DSUI_RS13390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSUI_RS13395	COG0509	glycine decarboxylation via glycine cleavage system
DSUI_RS13400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSUI_RS13400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSUI_RS13410	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSUI_RS13425	COG0443	Heat shock 70 kDa protein
DSUI_RS13445	COG0488	(ABC) transporter
DSUI_RS13450	COG3739	integral membrane protein
DSUI_RS13465	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSUI_RS13465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSUI_RS13470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSUI_RS13470	COG0189	ligase activity
DSUI_RS13475	COG1132	(ABC) transporter
DSUI_RS13485	COG0826	peptidase U32
DSUI_RS13490	COG2900	Belongs to the SlyX family
DSUI_RS13500	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSUI_RS13510	COG1187	pseudouridine synthase activity
DSUI_RS13515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSUI_RS13530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DSUI_RS13565	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSUI_RS13570	COG4681	YaeQ
DSUI_RS13595	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSUI_RS13610	COG0784	Response regulator, receiver
DSUI_RS13625	COG2205	protein histidine kinase activity
DSUI_RS13625	COG0784	Response regulator, receiver
DSUI_RS13645	COG0187	DNA topoisomerase II activity
DSUI_RS13650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSUI_RS13660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSUI_RS13695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSUI_RS13700	COG1388	LysM domain
DSUI_RS13700	COG0741	lytic transglycosylase activity
DSUI_RS13705	COG2814	Major facilitator Superfamily
DSUI_RS13715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSUI_RS13720	COG0601	transmembrane transport
DSUI_RS13725	COG0493	'glutamate synthase
DSUI_RS13725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSUI_RS13750	COG1024	Enoyl-CoA hydratase
DSUI_RS13755	COG0318	PFAM AMP-dependent synthetase and ligase
DSUI_RS13770	COG1127	ABC transporter
DSUI_RS13775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSUI_RS13780	COG0248	Ppx GppA phosphatase
DSUI_RS13785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DSUI_RS13790	COG0431	NADPH-dependent FMN reductase
DSUI_RS13795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSUI_RS13805	COG3228	Belongs to the MtfA family
DSUI_RS13815	COG0596	Alpha beta hydrolase
DSUI_RS13820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSUI_RS13945	COG3210	domain, Protein
DSUI_RS13965	COG0840	transmembrane signaling receptor activity
DSUI_RS13970	COG1136	(ABC) transporter
DSUI_RS13985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSUI_RS13990	COG0697	spore germination
DSUI_RS14000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSUI_RS14005	COG0784	Response regulator, receiver
DSUI_RS14005	COG2205	protein histidine kinase activity
DSUI_RS14005	COG5002	protein histidine kinase activity
DSUI_RS14025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSUI_RS14025	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DSUI_RS14030	COG0583	DNA-binding transcription factor activity
DSUI_RS14050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSUI_RS14065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS14070	COG0577	efflux transmembrane transporter activity
DSUI_RS14070	COG1136	(ABC) transporter
DSUI_RS14075	COG1136	(ABC) transporter
DSUI_RS14075	COG0577	efflux transmembrane transporter activity
DSUI_RS14090	COG0156	8-amino-7-oxononanoate synthase activity
DSUI_RS14095	COG2267	carboxylic ester hydrolase activity
DSUI_RS14100	COG2226	methyltransferase
DSUI_RS14105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DSUI_RS14115	COG2917	probably involved in intracellular septation
DSUI_RS14120	COG2350	Protein conserved in bacteria
DSUI_RS14130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSUI_RS14135	COG2200	EAL domain
DSUI_RS14145	COG0047	phosphoribosylformylglycinamidine synthase activity
DSUI_RS14145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSUI_RS14150	COG3706	GGDEF domain
DSUI_RS14175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSUI_RS14175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSUI_RS14185	COG0069	glutamate synthase activity
DSUI_RS14195	COG2890	protein-(glutamine-N5) methyltransferase activity
DSUI_RS14220	COG0436	Aminotransferase
DSUI_RS14225	COG0436	Aminotransferase
DSUI_RS14235	COG2076	Multidrug Resistance protein
DSUI_RS14250	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
DSUI_RS14290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DSUI_RS14305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSUI_RS14315	COG0791	NLP P60 protein
DSUI_RS14320	COG1840	ABC-type Fe3 transport system, periplasmic component
DSUI_RS14390	COG1178	ABC-type Fe3 transport system permease component
DSUI_RS14395	COG3842	ATPase activity
DSUI_RS14410	COG0513	Belongs to the DEAD box helicase family
DSUI_RS14415	COG1451	nucleotide metabolic process
DSUI_RS14420	COG1595	DNA-templated transcription, initiation
DSUI_RS14425	COG3712	iron ion homeostasis
DSUI_RS14430	COG4774	siderophore transport
DSUI_RS14455	COG0310	cobalt ion transport
DSUI_RS14470	COG1122	ATPase activity
DSUI_RS14490	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DSUI_RS14525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSUI_RS14525	COG1648	precorrin-2 dehydrogenase activity
DSUI_RS14535	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSUI_RS14540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DSUI_RS14545	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DSUI_RS14565	COG1595	DNA-templated transcription, initiation
DSUI_RS14570	COG0167	dihydroorotate dehydrogenase activity
DSUI_RS14575	COG4657	Part of a membrane complex involved in electron transport
DSUI_RS14580	COG2878	Part of a membrane complex involved in electron transport
DSUI_RS14600	COG4660	Part of a membrane complex involved in electron transport
DSUI_RS14605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSUI_RS14625	COG0840	transmembrane signaling receptor activity
DSUI_RS14630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSUI_RS14650	COG0406	alpha-ribazole phosphatase activity
DSUI_RS14660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSUI_RS14695	COG0326	Molecular chaperone. Has ATPase activity
DSUI_RS14720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DSUI_RS14725	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DSUI_RS14730	COG5557	Pfam Polysulphide reductase, NrfD
DSUI_RS14735	COG0437	4 iron, 4 sulfur cluster binding
DSUI_RS14740	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DSUI_RS14775	COG2267	carboxylic ester hydrolase activity
DSUI_RS14790	COG0306	phosphate transporter
DSUI_RS14810	COG3259	Nickel-dependent hydrogenase
DSUI_RS14815	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
DSUI_RS14820	COG3383	formate dehydrogenase (NAD+) activity
DSUI_RS14825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSUI_RS14830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DSUI_RS14840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DSUI_RS14845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSUI_RS14855	COG0494	nUDIX hydrolase
DSUI_RS14860	COG1007	ATP synthesis coupled electron transport
DSUI_RS14875	COG0713	ATP synthesis coupled electron transport
DSUI_RS14885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSUI_RS14890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSUI_RS14895	COG1034	ATP synthesis coupled electron transport
DSUI_RS14905	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DSUI_RS14910	COG0649	NAD binding
DSUI_RS14915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSUI_RS14920	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSUI_RS14925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSUI_RS14940	COG0149	triose-phosphate isomerase activity
DSUI_RS14945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSUI_RS14955	COG0573	inorganic phosphate transmembrane transporter activity
DSUI_RS14960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSUI_RS14965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSUI_RS14975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSUI_RS14980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSUI_RS14985	COG1534	Rna-binding protein
DSUI_RS14995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSUI_RS15000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSUI_RS15005	COG0505	Belongs to the CarA family
DSUI_RS15010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSUI_RS15015	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSUI_RS15020	COG0735	belongs to the Fur family
DSUI_RS15025	COG2119	membrane
DSUI_RS15040	COG0497	DNA recombination
DSUI_RS15045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSUI_RS15050	COG1420	regulation of RNA biosynthetic process
DSUI_RS15055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DSUI_RS15070	COG0840	transmembrane signaling receptor activity
DSUI_RS15075	COG2815	serine threonine protein kinase
DSUI_RS15075	COG0515	serine threonine protein kinase
DSUI_RS15080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSUI_RS15085	COG0443	Heat shock 70 kDa protein
DSUI_RS15090	COG0484	heat shock protein binding
DSUI_RS15100	COG0215	cysteine-tRNA ligase activity
DSUI_RS15125	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSUI_RS15135	COG0861	Integral membrane protein TerC family
DSUI_RS15140	COG0514	ATP-dependent DNA helicase (RecQ)
DSUI_RS15150	COG1418	mRNA catabolic process
DSUI_RS15165	COG2169	Transcriptional regulator
DSUI_RS15165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSUI_RS15170	COG3145	DNA-N1-methyladenine dioxygenase activity
DSUI_RS15185	COG0583	DNA-binding transcription factor activity
DSUI_RS15190	COG0746	molybdenum cofactor guanylyltransferase activity
DSUI_RS15205	COG1253	flavin adenine dinucleotide binding
DSUI_RS15215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSUI_RS15225	COG2010	Cytochrome c
DSUI_RS15250	COG1845	cytochrome c oxidase, subunit III
DSUI_RS15290	COG0840	transmembrane signaling receptor activity
DSUI_RS15295	COG0840	transmembrane signaling receptor activity
DSUI_RS15300	COG0745	RESPONSE REGULATOR receiver
DSUI_RS15310	COG0535	radical SAM domain protein
DSUI_RS15320	COG0557	exoribonuclease II activity
DSUI_RS15335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSUI_RS15340	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DSUI_RS15350	COG0330	HflC and HflK could
DSUI_RS15355	COG0330	HflC and HflK could
DSUI_RS15360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSUI_RS15365	COG1923	regulation of RNA biosynthetic process
DSUI_RS15370	COG1160	GTP binding
DSUI_RS15375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSUI_RS15385	COG0124	histidyl-tRNA synthetase
DSUI_RS15390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSUI_RS15405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSUI_RS15410	COG0105	UTP biosynthetic process
DSUI_RS15420	COG0644	oxidoreductase
DSUI_RS15435	COG0745	RESPONSE REGULATOR receiver
DSUI_RS15440	COG2205	protein histidine kinase activity
DSUI_RS15470	COG1301	dicarboxylic acid transport
DSUI_RS15505	COG0037	tRNA processing
DSUI_RS15510	COG0825	malonyl-CoA metabolic process
DSUI_RS15550	COG0583	DNA-binding transcription factor activity
DSUI_RS15555	COG0513	Belongs to the DEAD box helicase family
DSUI_RS15570	COG1136	(ABC) transporter
DSUI_RS15570	COG0577	efflux transmembrane transporter activity
DSUI_RS15575	COG1136	(ABC) transporter
DSUI_RS15575	COG0577	efflux transmembrane transporter activity
DSUI_RS15580	COG2205	protein histidine kinase activity
DSUI_RS15585	COG0745	RESPONSE REGULATOR receiver
DSUI_RS15590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS15595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSUI_RS15630	COG0285	dihydrofolate synthase activity
DSUI_RS15635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DSUI_RS15640	COG0159	tryptophan synthase activity
DSUI_RS15645	COG0133	tryptophan synthase activity
DSUI_RS15650	COG0135	phosphoribosylanthranilate isomerase activity
DSUI_RS15655	COG0101	tRNA pseudouridine synthase activity
DSUI_RS15675	COG0473	3-isopropylmalate dehydrogenase activity
DSUI_RS15680	COG0066	3-isopropylmalate dehydratase activity
DSUI_RS15690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSUI_RS15705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSUI_RS15745	COG0318	PFAM AMP-dependent synthetase and ligase
DSUI_RS15755	COG1074	ATP-dependent DNA helicase activity
DSUI_RS15765	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSUI_RS15775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSUI_RS15780	COG0254	rRNA binding
DSUI_RS15795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DSUI_RS15805	COG2154	pterin-4-alpha-carbinolamine dehydratase
DSUI_RS15810	COG1162	GTPase activity
DSUI_RS15815	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DSUI_RS15820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSUI_RS15830	COG1305	Transglutaminase-like
DSUI_RS15845	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
DSUI_RS15865	COG2308	Evidence 4 Homologs of previously reported genes of
DSUI_RS15870	COG0840	transmembrane signaling receptor activity
DSUI_RS15875	COG0840	transmembrane signaling receptor activity
DSUI_RS15880	COG0183	Belongs to the thiolase family
DSUI_RS15890	COG0494	nUDIX hydrolase
DSUI_RS15905	COG0505	Belongs to the CarA family
DSUI_RS15910	COG1666	GTP binding
DSUI_RS15915	COG3123	guanosine phosphorylase activity
DSUI_RS15925	COG0137	argininosuccinate synthase activity
DSUI_RS15930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSUI_RS15935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSUI_RS15955	COG0268	Binds directly to 16S ribosomal RNA
DSUI_RS15965	COG1881	PFAM PEBP family protein
DSUI_RS15970	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSUI_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
DSUI_RS15985	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSUI_RS15990	COG0205	6-phosphofructokinase activity
DSUI_RS15995	COG0563	adenylate kinase activity
DSUI_RS16000	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DSUI_RS16005	COG2835	tetraacyldisaccharide 4'-kinase activity
DSUI_RS16010	COG1663	tetraacyldisaccharide 4'-kinase activity
DSUI_RS16015	COG0848	biopolymer transport protein
DSUI_RS16020	COG0811	peptide transport
DSUI_RS16025	COG1570	exodeoxyribonuclease VII activity
DSUI_RS16040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSUI_RS16070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSUI_RS16075	COG2864	formate dehydrogenase
DSUI_RS16080	COG0437	4 iron, 4 sulfur cluster binding
DSUI_RS16085	COG3383	formate dehydrogenase (NAD+) activity
DSUI_RS16085	COG0243	molybdopterin cofactor binding
DSUI_RS16090	COG3058	Necessary for formate dehydrogenase activity
DSUI_RS16095	COG5002	protein histidine kinase activity
DSUI_RS16100	COG2204	response regulator
DSUI_RS16110	COG1366	Belongs to the anti-sigma-factor antagonist family
DSUI_RS16120	COG3161	chorismate lyase activity
DSUI_RS16135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DSUI_RS16145	COG0538	isocitrate dehydrogenase activity
DSUI_RS16155	COG4651	solute:proton antiporter activity
DSUI_RS16155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSUI_RS16160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSUI_RS16175	COG1129	ABC transporter
DSUI_RS16180	COG0348	domain, Protein
DSUI_RS16185	COG0437	4 iron, 4 sulfur cluster binding
DSUI_RS16205	COG2863	cytochrome
DSUI_RS16210	COG4263	nitrous-oxide reductase activity
DSUI_RS16220	COG1999	signal sequence binding
DSUI_RS16255	COG2010	Cytochrome c
DSUI_RS16260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSUI_RS16260	COG1648	precorrin-2 dehydrogenase activity
DSUI_RS16265	COG1575	Belongs to the MenA family. Type 1 subfamily
DSUI_RS16275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DSUI_RS16280	COG0343	queuine tRNA-ribosyltransferase activity
DSUI_RS16285	COG1862	Preprotein translocase
DSUI_RS16290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSUI_RS16295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSUI_RS16305	COG3909	cytochrome
DSUI_RS16315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DSUI_RS16320	COG0625	glutathione transferase activity
DSUI_RS16345	COG0482	sulfurtransferase activity
DSUI_RS16370	COG0859	PFAM glycosyl transferase family 9
DSUI_RS16380	COG0429	hydrolase of the alpha beta-hydrolase fold
DSUI_RS16390	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSUI_RS16395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSUI_RS16425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS16445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSUI_RS16495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSUI_RS16505	COG0584	glycerophosphoryl diester phosphodiesterase
DSUI_RS16520	COG1960	acyl-CoA dehydrogenase activity
DSUI_RS16530	COG0667	Aldo Keto reductase
DSUI_RS16540	COG1283	sodium-dependent phosphate transmembrane transporter activity
DSUI_RS16550	COG0436	Aminotransferase
DSUI_RS16565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSUI_RS16570	COG0235	Class ii aldolase
DSUI_RS16585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSUI_RS16600	COG4566	intracellular signal transduction
DSUI_RS16605	COG4191	Histidine kinase
DSUI_RS16615	COG1024	Enoyl-CoA hydratase
DSUI_RS16625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSUI_RS16645	COG2814	Major facilitator Superfamily
DSUI_RS16655	COG2826	transposase and inactivated derivatives, IS30 family
DSUI_RS16665	COG0312	modulator of DNA gyrase
DSUI_RS16670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSUI_RS16680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSUI_RS16690	COG0513	Belongs to the DEAD box helicase family
DSUI_RS16710	COG0631	protein serine/threonine phosphatase activity
DSUI_RS16725	COG0247	lactate metabolic process
DSUI_RS16730	COG0277	FAD linked oxidase domain protein
DSUI_RS16735	COG0277	FAD linked oxidase domain protein
DSUI_RS16750	COG0730	response to heat
DSUI_RS16770	COG2703	oxygen carrier activity
DSUI_RS16775	COG3622	Belongs to the hyi family
DSUI_RS16780	COG2096	Adenosyltransferase
DSUI_RS16785	COG0251	oxidation-reduction process
DSUI_RS16790	COG0583	DNA-binding transcription factor activity
DSUI_RS16795	COG1335	isochorismatase
DSUI_RS16830	COG3811	Belongs to the UPF0386 family
DSUI_RS16840	COG2084	Dehydrogenase
DSUI_RS16850	COG2084	Dehydrogenase
DSUI_RS16870	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSUI_RS16875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSUI_RS16880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSUI_RS16895	COG0642	Histidine kinase
DSUI_RS16910	COG0427	acetyl-CoA hydrolase
DSUI_RS16915	COG2223	nitrite transmembrane transporter activity
DSUI_RS16920	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DSUI_RS16935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSUI_RS16945	COG3158	transport of potassium into the cell
DSUI_RS16950	COG0850	regulation of cytokinetic process
DSUI_RS16960	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DSUI_RS16975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSUI_RS16980	COG1116	anion transmembrane transporter activity
DSUI_RS16995	COG2204	response regulator
DSUI_RS17005	COG2197	response regulator
DSUI_RS17035	COG0840	transmembrane signaling receptor activity
DSUI_RS17040	COG0835	chemotaxis
DSUI_RS17055	COG0629	single-stranded DNA binding
DSUI_RS17060	COG2814	Major facilitator Superfamily
DSUI_RS17065	COG1027	Aspartate ammonia-lyase
DSUI_RS17070	COG1301	dicarboxylic acid transport
DSUI_RS17130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSUI_RS17135	COG1047	Peptidyl-prolyl cis-trans
DSUI_RS17140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSUI_RS17145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSUI_RS17150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSUI_RS17155	COG0196	riboflavin kinase activity
DSUI_RS17160	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSUI_RS17165	COG0802	atpase or kinase
DSUI_RS17170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSUI_RS17200	COG1722	exodeoxyribonuclease VII activity
DSUI_RS17205	COG0142	geranyltranstransferase activity
DSUI_RS17210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSUI_RS17215	COG1469	GTP cyclohydrolase I activity
DSUI_RS17220	COG0335	large ribosomal subunit rRNA binding
DSUI_RS17225	COG0336	Belongs to the RNA methyltransferase TrmD family
DSUI_RS17230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSUI_RS17235	COG0228	four-way junction DNA binding
DSUI_RS17245	COG1295	ribonuclease BN
DSUI_RS17255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSUI_RS17275	COG0745	RESPONSE REGULATOR receiver
DSUI_RS17285	COG1183	phosphatidylcholine synthase activity
DSUI_RS17290	COG0688	phosphatidylethanolamine metabolic process
DSUI_RS17295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSUI_RS17300	COG0440	acetolactate synthase activity
DSUI_RS17305	COG0028	Belongs to the TPP enzyme family
DSUI_RS17335	COG0795	lipopolysaccharide-transporting ATPase activity
DSUI_RS17340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSUI_RS17355	COG0525	valine-tRNA ligase activity
DSUI_RS17375	COG1216	Glycosyl transferase, family 2
DSUI_RS17380	COG1216	Glycosyl transferase, family 2
DSUI_RS17450	COG0840	transmembrane signaling receptor activity
DSUI_RS17500	COG2205	protein histidine kinase activity
DSUI_RS17500	COG5002	protein histidine kinase activity
DSUI_RS17500	COG0784	Response regulator, receiver
DSUI_RS17515	COG0741	lytic transglycosylase activity
DSUI_RS17585	COG0515	serine threonine protein kinase
DSUI_RS17585	COG2815	serine threonine protein kinase
DSUI_RS17590	COG4251	negative regulation of phosphorylation
DSUI_RS17625	COG3144	bacterial-type flagellum assembly
DSUI_RS17640	COG0582	viral genome integration into host DNA
DSUI_RS17675	COG3850	Histidine kinase
DSUI_RS17675	COG3437	response regulator, receiver
DSUI_RS17675	COG4999	Histidine kinase
DSUI_RS17675	COG2205	protein histidine kinase activity
DSUI_RS17710	COG2205	protein histidine kinase activity
DSUI_RS17710	COG0784	Response regulator, receiver
DSUI_RS17710	COG2198	Histidine kinase
DSUI_RS17735	COG0671	phosphoesterase, PA-phosphatase related
DSUI_RS17740	COG5001	Diguanylate cyclase
DSUI_RS17785	COG0642	Histidine kinase
DSUI_RS17800	COG5002	protein histidine kinase activity
DSUI_RS17800	COG5001	Diguanylate cyclase
DSUI_RS17805	COG1169	isochorismate synthase
DSUI_RS17810	COG4191	Histidine kinase
DSUI_RS17815	COG4191	Histidine kinase
DSUI_RS17840	COG3300	MHYT domain
DSUI_RS17840	COG5001	Diguanylate cyclase
DSUI_RS17845	COG5001	Diguanylate cyclase
DSUI_RS17845	COG3300	MHYT domain
DSUI_RS17855	COG2204	response regulator
DSUI_RS17860	COG2204	response regulator
DSUI_RS17870	COG1858	cytochrome C peroxidase
DSUI_RS17915	COG1216	Glycosyl transferase, family 2
DSUI_RS17940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSUI_RS17945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSUI_RS17950	COG0737	Belongs to the 5'-nucleotidase family
DSUI_RS17955	COG2204	response regulator
DSUI_RS17995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSUI_RS18020	COG1525	nuclease
DSUI_RS18090	COG2205	protein histidine kinase activity
DSUI_RS18105	COG1815	bacterial-type flagellum-dependent cell motility
DSUI_RS18160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DSUI_RS18180	COG2840	Smr protein MutS2
DSUI_RS18215	COG2965	DNA replication, synthesis of RNA primer
DSUI_RS18260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSUI_RS18315	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
DSUI_RS18320	COG4191	Histidine kinase