locus-tag	class	description
AZSP09_RS00010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZSP09_RS00015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZSP09_RS00020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZSP09_RS00025	COG0723	plastoquinol--plastocyanin reductase activity
AZSP09_RS00030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZSP09_RS00035	COG2857	Cytochrome c1
AZSP09_RS00040	COG0625	glutathione transferase activity
AZSP09_RS00045	COG2969	positive regulation of protein catabolic process
AZSP09_RS00050	COG0243	molybdopterin cofactor binding
AZSP09_RS00055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZSP09_RS00060	COG1942	4-Oxalocrotonate Tautomerase
AZSP09_RS00090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZSP09_RS00105	COG3707	response regulator
AZSP09_RS00120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZSP09_RS00130	COG1116	anion transmembrane transporter activity
AZSP09_RS00140	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS00185	COG0306	phosphate transporter
AZSP09_RS00190	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AZSP09_RS00200	COG0798	PFAM Bile acid sodium symporter
AZSP09_RS00205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZSP09_RS00215	COG2205	protein histidine kinase activity
AZSP09_RS00220	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS00240	COG1942	4-Oxalocrotonate Tautomerase
AZSP09_RS00250	COG0583	DNA-binding transcription factor activity
AZSP09_RS00260	COG0840	transmembrane signaling receptor activity
AZSP09_RS00285	COG3920	Histidine kinase
AZSP09_RS00290	COG2205	protein histidine kinase activity
AZSP09_RS00290	COG5002	protein histidine kinase activity
AZSP09_RS00290	COG0784	Response regulator, receiver
AZSP09_RS00295	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS00300	COG3437	response regulator, receiver
AZSP09_RS00300	COG3850	Histidine kinase
AZSP09_RS00300	COG2205	protein histidine kinase activity
AZSP09_RS00300	COG4999	Histidine kinase
AZSP09_RS00315	COG1538	Outer membrane efflux protein
AZSP09_RS00335	COG1742	UPF0060 membrane protein
AZSP09_RS00340	COG3058	Necessary for formate dehydrogenase activity
AZSP09_RS00345	COG0243	molybdopterin cofactor binding
AZSP09_RS00345	COG3383	formate dehydrogenase (NAD+) activity
AZSP09_RS00350	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_RS00355	COG2864	formate dehydrogenase
AZSP09_RS00360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZSP09_RS00365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZSP09_RS00395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZSP09_RS00410	COG1570	exodeoxyribonuclease VII activity
AZSP09_RS00415	COG0811	peptide transport
AZSP09_RS00420	COG0848	biopolymer transport protein
AZSP09_RS00425	COG1663	tetraacyldisaccharide 4'-kinase activity
AZSP09_RS00430	COG2835	tetraacyldisaccharide 4'-kinase activity
AZSP09_RS00435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZSP09_RS00440	COG0563	adenylate kinase activity
AZSP09_RS00445	COG0205	6-phosphofructokinase activity
AZSP09_RS00450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZSP09_RS00455	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_RS00465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZSP09_RS00470	COG1881	PFAM PEBP family protein
AZSP09_RS00480	COG0268	Binds directly to 16S ribosomal RNA
AZSP09_RS00500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZSP09_RS00505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZSP09_RS00510	COG0137	argininosuccinate synthase activity
AZSP09_RS00520	COG3123	guanosine phosphorylase activity
AZSP09_RS00525	COG1666	GTP binding
AZSP09_RS00530	COG0505	Belongs to the CarA family
AZSP09_RS00545	COG0494	nUDIX hydrolase
AZSP09_RS00555	COG0183	Belongs to the thiolase family
AZSP09_RS00560	COG0840	transmembrane signaling receptor activity
AZSP09_RS00565	COG0840	transmembrane signaling receptor activity
AZSP09_RS00570	COG2308	Evidence 4 Homologs of previously reported genes of
AZSP09_RS00590	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AZSP09_RS00605	COG1305	Transglutaminase-like
AZSP09_RS00615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZSP09_RS00620	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AZSP09_RS00625	COG1162	GTPase activity
AZSP09_RS00630	COG2154	pterin-4-alpha-carbinolamine dehydratase
AZSP09_RS00640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AZSP09_RS00655	COG0254	rRNA binding
AZSP09_RS00660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZSP09_RS00670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZSP09_RS00680	COG1074	ATP-dependent DNA helicase activity
AZSP09_RS00690	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS00730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZSP09_RS00745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZSP09_RS00755	COG0066	3-isopropylmalate dehydratase activity
AZSP09_RS00760	COG0473	3-isopropylmalate dehydrogenase activity
AZSP09_RS00780	COG0101	tRNA pseudouridine synthase activity
AZSP09_RS00785	COG0135	phosphoribosylanthranilate isomerase activity
AZSP09_RS00790	COG0133	tryptophan synthase activity
AZSP09_RS00795	COG0159	tryptophan synthase activity
AZSP09_RS00800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZSP09_RS00805	COG0285	dihydrofolate synthase activity
AZSP09_RS00840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_RS00845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS00850	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS00855	COG2205	protein histidine kinase activity
AZSP09_RS00860	COG1136	(ABC) transporter
AZSP09_RS00860	COG0577	efflux transmembrane transporter activity
AZSP09_RS00865	COG1136	(ABC) transporter
AZSP09_RS00865	COG0577	efflux transmembrane transporter activity
AZSP09_RS00880	COG0513	Belongs to the DEAD box helicase family
AZSP09_RS00885	COG0583	DNA-binding transcription factor activity
AZSP09_RS00915	COG0825	malonyl-CoA metabolic process
AZSP09_RS00920	COG0037	tRNA processing
AZSP09_RS00955	COG1301	dicarboxylic acid transport
AZSP09_RS00985	COG2205	protein histidine kinase activity
AZSP09_RS00990	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS01005	COG0644	oxidoreductase
AZSP09_RS01015	COG0105	UTP biosynthetic process
AZSP09_RS01020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZSP09_RS01035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZSP09_RS01040	COG0124	histidyl-tRNA synthetase
AZSP09_RS01050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_RS01055	COG1160	GTP binding
AZSP09_RS01060	COG1923	regulation of RNA biosynthetic process
AZSP09_RS01065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZSP09_RS01070	COG0330	HflC and HflK could
AZSP09_RS01075	COG0330	HflC and HflK could
AZSP09_RS01085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZSP09_RS01090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZSP09_RS01105	COG0557	exoribonuclease II activity
AZSP09_RS01115	COG0535	radical SAM domain protein
AZSP09_RS01125	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS01130	COG0840	transmembrane signaling receptor activity
AZSP09_RS01135	COG0840	transmembrane signaling receptor activity
AZSP09_RS01175	COG1845	cytochrome c oxidase, subunit III
AZSP09_RS01205	COG2010	Cytochrome c
AZSP09_RS01215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_RS01225	COG1253	flavin adenine dinucleotide binding
AZSP09_RS01240	COG0746	molybdenum cofactor guanylyltransferase activity
AZSP09_RS01245	COG0583	DNA-binding transcription factor activity
AZSP09_RS01260	COG3145	DNA-N1-methyladenine dioxygenase activity
AZSP09_RS01265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZSP09_RS01265	COG2169	Transcriptional regulator
AZSP09_RS01280	COG1418	mRNA catabolic process
AZSP09_RS01285	COG0514	ATP-dependent DNA helicase (RecQ)
AZSP09_RS01290	COG0861	Integral membrane protein TerC family
AZSP09_RS01300	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_RS01325	COG0215	cysteine-tRNA ligase activity
AZSP09_RS01335	COG0484	heat shock protein binding
AZSP09_RS01340	COG0443	Heat shock 70 kDa protein
AZSP09_RS01345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZSP09_RS01350	COG2815	serine threonine protein kinase
AZSP09_RS01350	COG0515	serine threonine protein kinase
AZSP09_RS01355	COG0840	transmembrane signaling receptor activity
AZSP09_RS01365	COG3118	belongs to the thioredoxin family
AZSP09_RS01370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZSP09_RS01375	COG1420	regulation of RNA biosynthetic process
AZSP09_RS01380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZSP09_RS01385	COG0497	DNA recombination
AZSP09_RS01400	COG2119	membrane
AZSP09_RS01405	COG0735	belongs to the Fur family
AZSP09_RS01410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_RS01415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZSP09_RS01420	COG0505	Belongs to the CarA family
AZSP09_RS01425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZSP09_RS01430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZSP09_RS01440	COG1534	Rna-binding protein
AZSP09_RS01445	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZSP09_RS01450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_RS01460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZSP09_RS01465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZSP09_RS01470	COG0573	inorganic phosphate transmembrane transporter activity
AZSP09_RS01480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZSP09_RS01485	COG0149	triose-phosphate isomerase activity
AZSP09_RS01500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_RS01505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_RS01510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_RS01515	COG0649	NAD binding
AZSP09_RS01520	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZSP09_RS01530	COG1034	ATP synthesis coupled electron transport
AZSP09_RS01535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZSP09_RS01540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_RS01550	COG0713	ATP synthesis coupled electron transport
AZSP09_RS01565	COG1007	ATP synthesis coupled electron transport
AZSP09_RS01570	COG0494	nUDIX hydrolase
AZSP09_RS01580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_RS01585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZSP09_RS01595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZSP09_RS01600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AZSP09_RS01605	COG3383	formate dehydrogenase (NAD+) activity
AZSP09_RS01610	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AZSP09_RS01615	COG3259	Nickel-dependent hydrogenase
AZSP09_RS01635	COG0306	phosphate transporter
AZSP09_RS01650	COG0596	Alpha beta hydrolase
AZSP09_RS01650	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_RS01685	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AZSP09_RS01690	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_RS01695	COG5557	Pfam Polysulphide reductase, NrfD
AZSP09_RS01700	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AZSP09_RS01705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZSP09_RS01730	COG0326	Molecular chaperone. Has ATPase activity
AZSP09_RS01735	COG4191	Histidine kinase
AZSP09_RS01750	COG4191	Histidine kinase
AZSP09_RS01765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_RS01775	COG0406	alpha-ribazole phosphatase activity
AZSP09_RS01800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_RS01805	COG0840	transmembrane signaling receptor activity
AZSP09_RS01825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZSP09_RS01830	COG4660	Part of a membrane complex involved in electron transport
AZSP09_RS01850	COG2878	Part of a membrane complex involved in electron transport
AZSP09_RS01860	COG0167	dihydroorotate dehydrogenase activity
AZSP09_RS01865	COG1595	DNA-templated transcription, initiation
AZSP09_RS01885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AZSP09_RS01890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZSP09_RS01895	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_RS01905	COG1648	precorrin-2 dehydrogenase activity
AZSP09_RS01905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZSP09_RS01940	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZSP09_RS01960	COG1122	ATPase activity
AZSP09_RS01975	COG0310	cobalt ion transport
AZSP09_RS01995	COG1451	nucleotide metabolic process
AZSP09_RS02000	COG0513	Belongs to the DEAD box helicase family
AZSP09_RS02010	COG3842	ATPase activity
AZSP09_RS02015	COG1178	ABC-type Fe3 transport system permease component
AZSP09_RS02060	COG5310	Homospermidine synthase
AZSP09_RS02065	COG0754	glutathionylspermidine amidase activity
AZSP09_RS02105	COG1840	ABC-type Fe3 transport system, periplasmic component
AZSP09_RS02110	COG0791	NLP P60 protein
AZSP09_RS02120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_RS02135	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AZSP09_RS02140	COG1169	isochorismate synthase
AZSP09_RS02175	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZSP09_RS02185	COG0726	polysaccharide deacetylase
AZSP09_RS02190	COG2076	Multidrug Resistance protein
AZSP09_RS02200	COG0436	Aminotransferase
AZSP09_RS02205	COG0436	Aminotransferase
AZSP09_RS02225	COG2890	protein-(glutamine-N5) methyltransferase activity
AZSP09_RS02235	COG0069	glutamate synthase activity
AZSP09_RS02245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZSP09_RS02245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZSP09_RS02270	COG5002	protein histidine kinase activity
AZSP09_RS02270	COG5001	Diguanylate cyclase
AZSP09_RS02275	COG3706	GGDEF domain
AZSP09_RS02280	COG0047	phosphoribosylformylglycinamidine synthase activity
AZSP09_RS02280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZSP09_RS02290	COG2200	EAL domain
AZSP09_RS02295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_RS02305	COG2350	Protein conserved in bacteria
AZSP09_RS02310	COG2917	probably involved in intracellular septation
AZSP09_RS02320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZSP09_RS02325	COG2226	methyltransferase
AZSP09_RS02330	COG2267	carboxylic ester hydrolase activity
AZSP09_RS02335	COG0156	8-amino-7-oxononanoate synthase activity
AZSP09_RS02350	COG0577	efflux transmembrane transporter activity
AZSP09_RS02350	COG1136	(ABC) transporter
AZSP09_RS02355	COG1136	(ABC) transporter
AZSP09_RS02355	COG0577	efflux transmembrane transporter activity
AZSP09_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS02375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZSP09_RS02395	COG0583	DNA-binding transcription factor activity
AZSP09_RS02400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZSP09_RS02400	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AZSP09_RS02420	COG2205	protein histidine kinase activity
AZSP09_RS02420	COG5002	protein histidine kinase activity
AZSP09_RS02420	COG0784	Response regulator, receiver
AZSP09_RS02425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZSP09_RS02435	COG0697	spore germination
AZSP09_RS02440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZSP09_RS02455	COG1136	(ABC) transporter
AZSP09_RS02465	COG0840	transmembrane signaling receptor activity
AZSP09_RS02480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZSP09_RS02485	COG0596	Alpha beta hydrolase
AZSP09_RS02495	COG3228	Belongs to the MtfA family
AZSP09_RS02505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZSP09_RS02510	COG0431	NADPH-dependent FMN reductase
AZSP09_RS02515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZSP09_RS02520	COG0248	Ppx GppA phosphatase
AZSP09_RS02525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZSP09_RS02530	COG1127	ABC transporter
AZSP09_RS02545	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS02550	COG1024	Enoyl-CoA hydratase
AZSP09_RS02555	COG4191	Histidine kinase
AZSP09_RS02575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZSP09_RS02575	COG0493	'glutamate synthase
AZSP09_RS02580	COG0601	transmembrane transport
AZSP09_RS02585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_RS02595	COG2814	Major facilitator Superfamily
AZSP09_RS02600	COG0741	lytic transglycosylase activity
AZSP09_RS02600	COG1388	LysM domain
AZSP09_RS02605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZSP09_RS02640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_RS02650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZSP09_RS02655	COG0187	DNA topoisomerase II activity
AZSP09_RS02670	COG0784	Response regulator, receiver
AZSP09_RS02670	COG2205	protein histidine kinase activity
AZSP09_RS02685	COG0784	Response regulator, receiver
AZSP09_RS02690	COG0642	Histidine kinase
AZSP09_RS02705	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZSP09_RS02715	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AZSP09_RS02735	COG4681	YaeQ
AZSP09_RS02740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZSP09_RS02775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZSP09_RS02790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZSP09_RS02795	COG1187	pseudouridine synthase activity
AZSP09_RS02805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZSP09_RS02815	COG2900	Belongs to the SlyX family
AZSP09_RS02820	COG0826	peptidase U32
AZSP09_RS02830	COG1132	(ABC) transporter
AZSP09_RS02835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZSP09_RS02835	COG0189	ligase activity
AZSP09_RS02840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZSP09_RS02840	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZSP09_RS02855	COG3739	integral membrane protein
AZSP09_RS02860	COG0488	(ABC) transporter
AZSP09_RS02880	COG0443	Heat shock 70 kDa protein
AZSP09_RS02895	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_RS02905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZSP09_RS02905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZSP09_RS02910	COG0509	glycine decarboxylation via glycine cleavage system
AZSP09_RS02915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZSP09_RS02935	COG0613	PHP domain protein
AZSP09_RS02940	COG0009	L-threonylcarbamoyladenylate synthase
AZSP09_RS02945	COG1994	Peptidase M50
AZSP09_RS02950	COG0180	Tryptophanyl-tRNA synthetase
AZSP09_RS02955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZSP09_RS02960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZSP09_RS02965	COG1187	pseudouridine synthase activity
AZSP09_RS02970	COG0779	Required for maturation of 30S ribosomal subunits
AZSP09_RS02975	COG0195	Participates in both transcription termination and antitermination
AZSP09_RS02975	COG2251	uridine kinase activity
AZSP09_RS02980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZSP09_RS02985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZSP09_RS02990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZSP09_RS02995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZSP09_RS03000	COG1185	polyribonucleotide nucleotidyltransferase activity
AZSP09_RS03005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZSP09_RS03025	COG0330	HflC and HflK could
AZSP09_RS03035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZSP09_RS03045	COG2171	N-acyltransferase activity
AZSP09_RS03050	COG0436	Aminotransferase
AZSP09_RS03060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZSP09_RS03065	COG2252	PERMEase
AZSP09_RS03070	COG3318	Belongs to the UPF0149 family
AZSP09_RS03070	COG3012	SEC-C Motif Domain Protein
AZSP09_RS03085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZSP09_RS03090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZSP09_RS03095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZSP09_RS03105	COG0242	peptide deformylase activity
AZSP09_RS03110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZSP09_RS03120	COG0052	Belongs to the universal ribosomal protein uS2 family
AZSP09_RS03125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZSP09_RS03130	COG0528	UMP kinase activity
AZSP09_RS03135	COG0233	cytoplasmic translational termination
AZSP09_RS03140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZSP09_RS03145	COG0575	Belongs to the CDS family
AZSP09_RS03150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZSP09_RS03160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_RS03170	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_RS03175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZSP09_RS03180	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_RS03185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_RS03190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZSP09_RS03195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZSP09_RS03200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZSP09_RS03210	COG2860	membrane
AZSP09_RS03215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZSP09_RS03220	COG2867	negative regulation of translational initiation
AZSP09_RS03225	COG2914	Belongs to the UPF0125 (RnfH) family
AZSP09_RS03240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZSP09_RS03240	COG0519	Catalyzes the synthesis of GMP from XMP
AZSP09_RS03260	COG1733	regulation of RNA biosynthetic process
AZSP09_RS03265	COG0702	epimerase
AZSP09_RS03295	COG1278	Cold shock
AZSP09_RS03310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZSP09_RS03315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZSP09_RS03330	COG0084	hydrolase, TatD family'
AZSP09_RS03340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_RS03360	COG4644	lycopene metabolic process
AZSP09_RS03370	COG0789	Transcriptional regulator
AZSP09_RS03375	COG1742	UPF0060 membrane protein
AZSP09_RS03385	COG5002	protein histidine kinase activity
AZSP09_RS03420	COG3039	Transposase
AZSP09_RS03425	COG1815	bacterial-type flagellum-dependent cell motility
AZSP09_RS03435	COG2119	membrane
AZSP09_RS03455	COG1959	2 iron, 2 sulfur cluster binding
AZSP09_RS03460	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZSP09_RS03465	COG3300	MHYT domain
AZSP09_RS03465	COG5001	Diguanylate cyclase
AZSP09_RS03470	COG2183	response to ionizing radiation
AZSP09_RS03475	COG1393	Belongs to the ArsC family
AZSP09_RS03480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZSP09_RS03490	COG0277	FAD linked oxidase domain protein
AZSP09_RS03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_RS03500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZSP09_RS03515	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_RS03535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZSP09_RS03540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZSP09_RS03550	COG0564	pseudouridine synthase activity
AZSP09_RS03560	COG2815	serine threonine protein kinase
AZSP09_RS03560	COG0515	serine threonine protein kinase
AZSP09_RS03580	COG4251	negative regulation of phosphorylation
AZSP09_RS03580	COG3706	GGDEF domain
AZSP09_RS03580	COG2203	Gaf domain
AZSP09_RS03580	COG5001	Diguanylate cyclase
AZSP09_RS03585	COG2201	protein-glutamate methylesterase activity
AZSP09_RS03590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_RS03595	COG2226	methyltransferase
AZSP09_RS03600	COG0328	RNA-DNA hybrid ribonuclease activity
AZSP09_RS03605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZSP09_RS03660	COG0322	excinuclease ABC activity
AZSP09_RS03675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZSP09_RS03680	COG1793	dna ligase
AZSP09_RS03685	COG1472	Belongs to the glycosyl hydrolase 3 family
AZSP09_RS03690	COG0736	holo-[acyl-carrier-protein] synthase activity
AZSP09_RS03695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZSP09_RS03700	COG1381	Involved in DNA repair and RecF pathway recombination
AZSP09_RS03705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZSP09_RS03710	COG0571	ribonuclease III activity
AZSP09_RS03720	COG0681	Belongs to the peptidase S26 family
AZSP09_RS03725	COG0481	GTPase activity
AZSP09_RS03735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_RS03745	COG1595	DNA-templated transcription, initiation
AZSP09_RS03750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZSP09_RS03760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZSP09_RS03765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZSP09_RS03780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZSP09_RS03785	COG0416	fatty acid biosynthetic process
AZSP09_RS03790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZSP09_RS03800	COG0424	maF-like protein
AZSP09_RS03805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZSP09_RS03810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZSP09_RS03810	COG0616	signal peptide processing
AZSP09_RS03830	COG1530	ribonuclease E activity
AZSP09_RS03835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZSP09_RS03840	COG0556	nucleotide-excision repair
AZSP09_RS03875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZSP09_RS03890	COG1217	gtp-binding protein TYPA
AZSP09_RS03900	COG2200	EAL domain
AZSP09_RS03900	COG3287	FIST C domain
AZSP09_RS03900	COG2199	diguanylate cyclase activity
AZSP09_RS03905	COG1032	radical SAM domain protein
AZSP09_RS03930	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AZSP09_RS03945	COG5001	Diguanylate cyclase
AZSP09_RS03950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZSP09_RS03955	COG0583	DNA-binding transcription factor activity
AZSP09_RS03960	COG0477	Major facilitator Superfamily
AZSP09_RS03970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AZSP09_RS03975	COG1704	LemA family
AZSP09_RS03980	COG1573	uracil-dna glycosylase
AZSP09_RS03985	COG0456	acetyltransferase
AZSP09_RS04010	COG0671	phosphoesterase, PA-phosphatase related
AZSP09_RS04050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZSP09_RS04055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZSP09_RS04065	COG1355	regulation of microtubule-based process
AZSP09_RS04080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZSP09_RS04100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZSP09_RS04105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZSP09_RS04110	COG0560	Phosphoserine phosphatase
AZSP09_RS04130	COG0443	Heat shock 70 kDa protein
AZSP09_RS04135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AZSP09_RS04145	COG0822	iron-sulfur transferase activity
AZSP09_RS04150	COG1104	cysteine desulfurase activity
AZSP09_RS04155	COG1104	cysteine desulfurase activity
AZSP09_RS04175	COG0483	inositol monophosphate 1-phosphatase activity
AZSP09_RS04210	COG2204	response regulator
AZSP09_RS04220	COG2205	protein histidine kinase activity
AZSP09_RS04225	COG2353	YceI-like domain
AZSP09_RS04235	COG3038	cytochrome b561
AZSP09_RS04240	COG3384	dioxygenase
AZSP09_RS04245	COG0583	DNA-binding transcription factor activity
AZSP09_RS04260	COG0789	Transcriptional regulator
AZSP09_RS04265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZSP09_RS04275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZSP09_RS04285	COG2501	S4 domain
AZSP09_RS04300	COG1131	(ABC) transporter
AZSP09_RS04305	COG0842	Transport permease protein
AZSP09_RS04310	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_RS04330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZSP09_RS04335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZSP09_RS04350	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_RS04390	COG3210	domain, Protein
AZSP09_RS04395	COG2831	hemolysin activation secretion protein
AZSP09_RS04410	COG3012	SEC-C Motif Domain Protein
AZSP09_RS04425	COG3022	response to hydroperoxide
AZSP09_RS04445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AZSP09_RS04450	COG0148	phosphopyruvate hydratase activity
AZSP09_RS04465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZSP09_RS04470	COG0504	CTP synthase activity
AZSP09_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_RS04480	COG1335	isochorismatase
AZSP09_RS04485	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AZSP09_RS04490	COG0709	Synthesizes selenophosphate from selenide and ATP
AZSP09_RS04500	COG4181	ATPase activity
AZSP09_RS04505	COG1309	transcriptional regulator
AZSP09_RS04525	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS04530	COG2200	EAL domain
AZSP09_RS04550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_RS04555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_RS04570	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_RS04585	COG2995	paraquat-inducible protein a
AZSP09_RS04590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZSP09_RS04590	COG3008	intermembrane lipid transfer
AZSP09_RS04600	COG0308	aminopeptidase N
AZSP09_RS04645	COG3655	Transcriptional regulator
AZSP09_RS04675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZSP09_RS04695	COG0587	DNA-directed DNA polymerase activity
AZSP09_RS04700	COG3550	peptidyl-serine autophosphorylation
AZSP09_RS04745	COG0583	DNA-binding transcription factor activity
AZSP09_RS04760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_RS04765	COG3135	benzoate transporter
AZSP09_RS04775	COG2198	Histidine kinase
AZSP09_RS04775	COG0784	Response regulator, receiver
AZSP09_RS04775	COG2205	protein histidine kinase activity
AZSP09_RS04780	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_RS04810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZSP09_RS04830	COG0784	Response regulator, receiver
AZSP09_RS04830	COG2205	protein histidine kinase activity
AZSP09_RS04830	COG5002	protein histidine kinase activity
AZSP09_RS04835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZSP09_RS04840	COG0747	negative chemotaxis
AZSP09_RS04845	COG0601	transmembrane transport
AZSP09_RS04850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_RS04900	COG0583	DNA-binding transcription factor activity
AZSP09_RS04910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_RS04920	COG2832	Protein of unknown function (DUF454)
AZSP09_RS04925	COG1067	ATP-dependent peptidase activity
AZSP09_RS04935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZSP09_RS04945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZSP09_RS04950	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_RS04955	COG0567	Dehydrogenase, E1 component
AZSP09_RS04965	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AZSP09_RS04975	COG1053	succinate dehydrogenase
AZSP09_RS04985	COG2009	succinate dehydrogenase
AZSP09_RS04995	COG0039	L-malate dehydrogenase activity
AZSP09_RS05040	COG2948	multi-organism process
AZSP09_RS05065	COG3451	type IV secretory pathway VirB4
AZSP09_RS05075	COG3838	Conjugal transfer protein Trbc
AZSP09_RS05080	COG4962	Type ii secretion system protein e
AZSP09_RS05100	COG0583	DNA-binding transcription factor activity
AZSP09_RS05105	COG1846	Transcriptional regulator
AZSP09_RS05130	COG1764	response to oxidative stress
AZSP09_RS05145	COG4959	Type IV secretory pathway protease TraF
AZSP09_RS05160	COG1192	Involved in chromosome partitioning
AZSP09_RS05205	COG5489	Protein of unknown function (DUF736)
AZSP09_RS05260	COG2003	Belongs to the UPF0758 family
AZSP09_RS05320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_RS05340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZSP09_RS05345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZSP09_RS05350	COG0740	serine-type endopeptidase activity
AZSP09_RS05355	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZSP09_RS05365	COG1562	ergosterol biosynthetic process
AZSP09_RS05370	COG1562	ergosterol biosynthetic process
AZSP09_RS05375	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AZSP09_RS05395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_RS05405	COG0519	Catalyzes the synthesis of GMP from XMP
AZSP09_RS05435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZSP09_RS05460	COG1764	response to oxidative stress
AZSP09_RS05465	COG1846	Transcriptional regulator
AZSP09_RS05485	COG2819	hydrolase of the alpha beta superfamily
AZSP09_RS05510	COG0727	PFAM Uncharacterised protein family (UPF0153)
AZSP09_RS05520	COG0542	response to heat
AZSP09_RS05535	COG2197	response regulator
AZSP09_RS05550	COG0314	molybdopterin synthase activity
AZSP09_RS05555	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZSP09_RS05560	COG0303	'Molybdopterin
AZSP09_RS05565	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZSP09_RS05575	COG1199	ATP-dependent helicase activity
AZSP09_RS05585	COG2974	May be involved in recombination
AZSP09_RS05590	COG0776	regulation of translation
AZSP09_RS05635	COG0720	synthase
AZSP09_RS05650	COG0527	aspartate kinase activity
AZSP09_RS05675	COG0776	regulation of translation
AZSP09_RS05690	COG0686	Belongs to the AlaDH PNT family
AZSP09_RS05700	COG0840	transmembrane signaling receptor activity
AZSP09_RS05705	COG2200	EAL domain
AZSP09_RS05705	COG3287	FIST C domain
AZSP09_RS05705	COG2199	diguanylate cyclase activity
AZSP09_RS05710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZSP09_RS05715	COG1116	anion transmembrane transporter activity
AZSP09_RS05735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZSP09_RS05740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZSP09_RS05750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_RS05755	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AZSP09_RS05760	COG1595	DNA-templated transcription, initiation
AZSP09_RS05765	COG4944	Protein of unknown function (DUF1109)
AZSP09_RS05775	COG1979	alcohol dehydrogenase
AZSP09_RS05780	COG0583	DNA-binding transcription factor activity
AZSP09_RS05790	COG1045	serine acetyltransferase
AZSP09_RS05795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS05800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZSP09_RS05820	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AZSP09_RS05840	COG1595	DNA-templated transcription, initiation
AZSP09_RS05850	COG1408	metallophosphoesterase
AZSP09_RS05870	COG1285	pathogenesis
AZSP09_RS05875	COG0583	DNA-binding transcription factor activity
AZSP09_RS05885	COG3258	Cytochrome c
AZSP09_RS05890	COG2863	cytochrome
AZSP09_RS05910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZSP09_RS05915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_RS05920	COG4566	intracellular signal transduction
AZSP09_RS05925	COG4191	Histidine kinase
AZSP09_RS05930	COG4654	Cytochrome c, class I
AZSP09_RS05945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZSP09_RS05965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZSP09_RS05980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZSP09_RS05985	COG2011	ABC-type metal ion transport system permease component
AZSP09_RS06005	COG0683	leucine binding
AZSP09_RS06045	COG1403	HNH endonuclease
AZSP09_RS06060	COG4178	(ABC) transporter
AZSP09_RS06065	COG0488	(ABC) transporter
AZSP09_RS06090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZSP09_RS06095	COG0626	cystathionine gamma-synthase activity
AZSP09_RS06100	COG1024	Enoyl-CoA hydratase
AZSP09_RS06105	COG1832	CoA-binding protein
AZSP09_RS06130	COG0583	DNA-binding transcription factor activity
AZSP09_RS06135	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AZSP09_RS06140	COG0583	DNA-binding transcription factor activity
AZSP09_RS06170	COG2827	Endonuclease containing a URI domain
AZSP09_RS06175	COG1538	Outer membrane efflux protein
AZSP09_RS06185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS06190	COG0657	acetylesterase activity
AZSP09_RS06195	COG0583	DNA-binding transcription factor activity
AZSP09_RS06200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AZSP09_RS06210	COG0732	type I restriction modification DNA specificity domain
AZSP09_RS06215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZSP09_RS06240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZSP09_RS06245	COG2176	DNA-directed DNA polymerase activity
AZSP09_RS06255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_RS06275	COG0251	oxidation-reduction process
AZSP09_RS06285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZSP09_RS06290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AZSP09_RS06305	COG0305	Participates in initiation and elongation during chromosome replication
AZSP09_RS06310	COG0359	binds to the 23S rRNA
AZSP09_RS06315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZSP09_RS06320	COG2965	DNA replication, synthesis of RNA primer
AZSP09_RS06325	COG0360	Binds together with S18 to 16S ribosomal RNA
AZSP09_RS06330	COG0583	DNA-binding transcription factor activity
AZSP09_RS06335	COG0730	response to heat
AZSP09_RS06350	COG0175	sulfate reduction
AZSP09_RS06360	COG2895	sulfate adenylyltransferase (ATP) activity
AZSP09_RS06365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZSP09_RS06385	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AZSP09_RS06390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZSP09_RS06395	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZSP09_RS06400	COG0714	Associated with various cellular activities
AZSP09_RS06415	COG2951	lytic endotransglycosylase activity
AZSP09_RS06430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZSP09_RS06435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AZSP09_RS06455	COG0776	regulation of translation
AZSP09_RS06460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_RS06460	COG0072	phenylalanine-tRNA ligase activity
AZSP09_RS06465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZSP09_RS06470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZSP09_RS06475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZSP09_RS06480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZSP09_RS06485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZSP09_RS06510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZSP09_RS06515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZSP09_RS06545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AZSP09_RS06555	COG0776	regulation of translation
AZSP09_RS06565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZSP09_RS06580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZSP09_RS06595	COG0402	S-adenosylhomocysteine deaminase activity
AZSP09_RS06605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZSP09_RS06610	COG0546	phosphoglycolate phosphatase activity
AZSP09_RS06650	COG0440	acetolactate synthase activity
AZSP09_RS06655	COG0028	Belongs to the TPP enzyme family
AZSP09_RS06665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_RS06665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_RS06670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_RS06675	COG4771	TonB-dependent receptor
AZSP09_RS06690	COG1429	ligase activity, forming nitrogen-metal bonds
AZSP09_RS06695	COG1944	ATP diphosphatase activity
AZSP09_RS06705	COG1294	oxidase, subunit
AZSP09_RS06725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZSP09_RS06730	COG1475	DNA binding
AZSP09_RS06740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZSP09_RS06745	COG0583	DNA-binding transcription factor activity
AZSP09_RS06750	COG1811	Na channel or pump
AZSP09_RS06755	COG4999	Histidine kinase
AZSP09_RS06755	COG3850	Histidine kinase
AZSP09_RS06755	COG3437	response regulator, receiver
AZSP09_RS06755	COG2205	protein histidine kinase activity
AZSP09_RS06760	COG1448	Aminotransferase
AZSP09_RS06780	COG3634	alkyl hydroperoxide reductase activity
AZSP09_RS06795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZSP09_RS06805	COG2814	Major facilitator Superfamily
AZSP09_RS06810	COG1704	LemA family
AZSP09_RS06825	COG0583	DNA-binding transcription factor activity
AZSP09_RS06830	COG4948	Mandelate Racemase Muconate Lactonizing
AZSP09_RS06840	COG1418	mRNA catabolic process
AZSP09_RS06840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZSP09_RS06855	COG2204	response regulator
AZSP09_RS06865	COG0488	(ABC) transporter
AZSP09_RS06885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZSP09_RS06890	COG0697	spore germination
AZSP09_RS06895	COG1902	pentaerythritol trinitrate reductase activity
AZSP09_RS06900	COG1309	transcriptional regulator
AZSP09_RS06910	COG5002	protein histidine kinase activity
AZSP09_RS06915	COG2204	response regulator
AZSP09_RS06925	COG1366	Belongs to the anti-sigma-factor antagonist family
AZSP09_RS06935	COG3161	chorismate lyase activity
AZSP09_RS06950	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AZSP09_RS06960	COG0538	isocitrate dehydrogenase activity
AZSP09_RS06970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZSP09_RS06970	COG4651	solute:proton antiporter activity
AZSP09_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_RS06990	COG1129	ABC transporter
AZSP09_RS06995	COG0348	domain, Protein
AZSP09_RS07000	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_RS07020	COG2863	cytochrome
AZSP09_RS07025	COG4263	nitrous-oxide reductase activity
AZSP09_RS07035	COG1999	signal sequence binding
AZSP09_RS07070	COG2010	Cytochrome c
AZSP09_RS07075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZSP09_RS07075	COG1648	precorrin-2 dehydrogenase activity
AZSP09_RS07080	COG1575	Belongs to the MenA family. Type 1 subfamily
AZSP09_RS07090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZSP09_RS07095	COG0343	queuine tRNA-ribosyltransferase activity
AZSP09_RS07100	COG1862	Preprotein translocase
AZSP09_RS07105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZSP09_RS07110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZSP09_RS07120	COG3909	cytochrome
AZSP09_RS07135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZSP09_RS07140	COG0625	glutathione transferase activity
AZSP09_RS07145	COG2204	response regulator
AZSP09_RS07155	COG2204	response regulator
AZSP09_RS07160	COG0482	sulfurtransferase activity
AZSP09_RS07185	COG0859	PFAM glycosyl transferase family 9
AZSP09_RS07195	COG0429	hydrolase of the alpha beta-hydrolase fold
AZSP09_RS07205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_RS07210	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_RS07235	COG1858	cytochrome C peroxidase
AZSP09_RS07240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS07245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZSP09_RS07255	COG0584	glycerophosphoryl diester phosphodiesterase
AZSP09_RS07270	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS07280	COG1988	membrane-bound metal-dependent
AZSP09_RS07285	COG0667	Aldo Keto reductase
AZSP09_RS07295	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZSP09_RS07310	COG0436	Aminotransferase
AZSP09_RS07325	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZSP09_RS07330	COG0235	Class ii aldolase
AZSP09_RS07345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS07360	COG4566	intracellular signal transduction
AZSP09_RS07365	COG4191	Histidine kinase
AZSP09_RS07375	COG1024	Enoyl-CoA hydratase
AZSP09_RS07390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZSP09_RS07410	COG2814	Major facilitator Superfamily
AZSP09_RS07445	COG0312	modulator of DNA gyrase
AZSP09_RS07450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZSP09_RS07460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZSP09_RS07475	COG0513	Belongs to the DEAD box helicase family
AZSP09_RS07495	COG0631	protein serine/threonine phosphatase activity
AZSP09_RS07510	COG0247	lactate metabolic process
AZSP09_RS07515	COG0277	FAD linked oxidase domain protein
AZSP09_RS07520	COG0277	FAD linked oxidase domain protein
AZSP09_RS07535	COG0730	response to heat
AZSP09_RS07550	COG2703	oxygen carrier activity
AZSP09_RS07555	COG3622	Belongs to the hyi family
AZSP09_RS07560	COG2096	Adenosyltransferase
AZSP09_RS07565	COG0251	oxidation-reduction process
AZSP09_RS07570	COG0583	DNA-binding transcription factor activity
AZSP09_RS07575	COG1335	isochorismatase
AZSP09_RS07610	COG3811	Belongs to the UPF0386 family
AZSP09_RS07620	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZSP09_RS07645	COG2084	Dehydrogenase
AZSP09_RS07655	COG2084	Dehydrogenase
AZSP09_RS07675	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZSP09_RS07680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS07685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZSP09_RS07700	COG0642	Histidine kinase
AZSP09_RS07715	COG0427	acetyl-CoA hydrolase
AZSP09_RS07720	COG2223	nitrite transmembrane transporter activity
AZSP09_RS07725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZSP09_RS07740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_RS07750	COG3158	transport of potassium into the cell
AZSP09_RS07755	COG0850	regulation of cytokinetic process
AZSP09_RS07765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZSP09_RS07785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZSP09_RS07790	COG1116	anion transmembrane transporter activity
AZSP09_RS07805	COG2204	response regulator
AZSP09_RS07815	COG2197	response regulator
AZSP09_RS07845	COG0840	transmembrane signaling receptor activity
AZSP09_RS07850	COG0835	chemotaxis
AZSP09_RS07865	COG0629	single-stranded DNA binding
AZSP09_RS07870	COG2814	Major facilitator Superfamily
AZSP09_RS07875	COG1027	Aspartate ammonia-lyase
AZSP09_RS07880	COG1301	dicarboxylic acid transport
AZSP09_RS07940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZSP09_RS07945	COG1047	Peptidyl-prolyl cis-trans
AZSP09_RS07950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_RS07955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZSP09_RS07960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZSP09_RS07965	COG0196	riboflavin kinase activity
AZSP09_RS07970	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZSP09_RS07975	COG0802	atpase or kinase
AZSP09_RS08010	COG1722	exodeoxyribonuclease VII activity
AZSP09_RS08015	COG0142	geranyltranstransferase activity
AZSP09_RS08020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZSP09_RS08025	COG1469	GTP cyclohydrolase I activity
AZSP09_RS08030	COG0335	large ribosomal subunit rRNA binding
AZSP09_RS08035	COG0336	Belongs to the RNA methyltransferase TrmD family
AZSP09_RS08040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZSP09_RS08045	COG0228	four-way junction DNA binding
AZSP09_RS08115	COG0582	viral genome integration into host DNA
AZSP09_RS08125	COG1295	ribonuclease BN
AZSP09_RS08135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZSP09_RS08155	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS08165	COG1183	phosphatidylcholine synthase activity
AZSP09_RS08170	COG0688	phosphatidylethanolamine metabolic process
AZSP09_RS08175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZSP09_RS08180	COG0440	acetolactate synthase activity
AZSP09_RS08185	COG0028	Belongs to the TPP enzyme family
AZSP09_RS08215	COG0795	lipopolysaccharide-transporting ATPase activity
AZSP09_RS08220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZSP09_RS08235	COG0525	valine-tRNA ligase activity
AZSP09_RS08245	COG0425	Belongs to the sulfur carrier protein TusA family
AZSP09_RS08255	COG0315	cyclic pyranopterin monophosphate synthase activity
AZSP09_RS08270	COG1278	Cold shock
AZSP09_RS08275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZSP09_RS08280	COG0542	response to heat
AZSP09_RS08285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZSP09_RS08290	COG2224	Isocitrate lyase
AZSP09_RS08305	COG2860	membrane
AZSP09_RS08315	COG0583	DNA-binding transcription factor activity
AZSP09_RS08325	COG0730	response to heat
AZSP09_RS08330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZSP09_RS08355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZSP09_RS08370	COG1253	flavin adenine dinucleotide binding
AZSP09_RS08375	COG1380	Effector of murein hydrolase LrgA
AZSP09_RS08380	COG1346	cytolysis
AZSP09_RS08395	COG2076	Multidrug Resistance protein
AZSP09_RS08400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZSP09_RS08405	COG0501	Belongs to the peptidase M48B family
AZSP09_RS08425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZSP09_RS08430	COG0537	adenosine 5'-monophosphoramidase activity
AZSP09_RS08435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZSP09_RS08440	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZSP09_RS08460	COG0708	Exodeoxyribonuclease III
AZSP09_RS08470	COG0339	signal peptide processing
AZSP09_RS08480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZSP09_RS08495	COG0778	Nitroreductase
AZSP09_RS08510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZSP09_RS08530	COG0840	transmembrane signaling receptor activity
AZSP09_RS08535	COG0009	L-threonylcarbamoyladenylate synthase
AZSP09_RS08540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZSP09_RS08545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZSP09_RS08550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZSP09_RS08580	COG2823	Periplasmic or secreted lipoprotein
AZSP09_RS08585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZSP09_RS08615	COG2833	Protein of unknown function (DUF455)
AZSP09_RS08635	COG2972	Histidine kinase
AZSP09_RS08635	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS08640	COG0165	Argininosuccinate lyase
AZSP09_RS08645	COG2815	serine threonine protein kinase
AZSP09_RS08645	COG0515	serine threonine protein kinase
AZSP09_RS08655	COG0004	ammonium transporteR
AZSP09_RS08675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZSP09_RS08680	COG2890	protein-(glutamine-N5) methyltransferase activity
AZSP09_RS08685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZSP09_RS08690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZSP09_RS08695	COG1490	D-aminoacyl-tRNA deacylase activity
AZSP09_RS08705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZSP09_RS08710	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_RS08715	COG1139	Iron-sulfur cluster binding protein
AZSP09_RS08735	COG0281	malic enzyme
AZSP09_RS08735	COG0280	phosphate acetyltransferase
AZSP09_RS08740	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AZSP09_RS08745	COG0436	Aminotransferase
AZSP09_RS08780	COG0142	geranyltranstransferase activity
AZSP09_RS08785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZSP09_RS08790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZSP09_RS08795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZSP09_RS08800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZSP09_RS08810	COG0134	indole-3-glycerol-phosphate synthase activity
AZSP09_RS08815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZSP09_RS08830	COG0546	phosphoglycolate phosphatase activity
AZSP09_RS08835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZSP09_RS08840	COG2967	ApaG domain
AZSP09_RS08845	COG2226	methyltransferase
AZSP09_RS08855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZSP09_RS08860	COG0653	protein targeting
AZSP09_RS08865	COG0739	heme binding
AZSP09_RS08880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AZSP09_RS08885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZSP09_RS08895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZSP09_RS08900	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZSP09_RS08905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZSP09_RS08910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZSP09_RS08915	COG0772	Belongs to the SEDS family
AZSP09_RS08920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZSP09_RS08925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZSP09_RS08930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZSP09_RS08935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZSP09_RS08945	COG3116	cell division
AZSP09_RS08950	COG0275	rRNA processing
AZSP09_RS08955	COG2001	Belongs to the MraZ family
AZSP09_RS08975	COG0418	dihydroorotase activity
AZSP09_RS08980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZSP09_RS08985	COG0792	nuclease activity
AZSP09_RS08995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZSP09_RS09010	COG1469	GTP cyclohydrolase I activity
AZSP09_RS09015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZSP09_RS09020	COG4208	sulfate ABC transporter
AZSP09_RS09030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZSP09_RS09040	COG1858	cytochrome C peroxidase
AZSP09_RS09045	COG2963	transposase activity
AZSP09_RS09055	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS09060	COG0367	asparagine synthase
AZSP09_RS09080	COG0463	Glycosyl transferase, family 2
AZSP09_RS09085	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS09145	COG0642	Histidine kinase
AZSP09_RS09155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS09160	COG0842	Transport permease protein
AZSP09_RS09160	COG1129	ABC transporter
AZSP09_RS09165	COG0842	Transport permease protein
AZSP09_RS09175	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS09180	COG2205	protein histidine kinase activity
AZSP09_RS09195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZSP09_RS09200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AZSP09_RS09205	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZSP09_RS09215	COG1671	Belongs to the UPF0178 family
AZSP09_RS09220	COG0459	protein refolding
AZSP09_RS09225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZSP09_RS09255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZSP09_RS09315	COG2217	Heavy metal translocating P-type atpase
AZSP09_RS09325	COG2205	protein histidine kinase activity
AZSP09_RS09355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS09360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_RS09400	COG1815	bacterial-type flagellum-dependent cell motility
AZSP09_RS09450	COG3162	membrane
AZSP09_RS09475	COG2027	D-alanyl-D-alanine carboxypeptidase
AZSP09_RS09490	COG1489	DNA binding
AZSP09_RS09495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS09515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZSP09_RS09520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZSP09_RS09615	COG0477	Major facilitator Superfamily
AZSP09_RS09620	COG0513	Belongs to the DEAD box helicase family
AZSP09_RS09625	COG1607	acyl-coa hydrolase
AZSP09_RS09630	COG0586	Pfam SNARE associated Golgi protein
AZSP09_RS09635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZSP09_RS09665	COG0183	Belongs to the thiolase family
AZSP09_RS09670	COG1024	Enoyl-CoA hydratase
AZSP09_RS09670	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_RS09675	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS09685	COG2067	long-chain fatty acid transport protein
AZSP09_RS09700	COG1307	EDD domain protein, DegV family
AZSP09_RS09705	COG0183	Belongs to the thiolase family
AZSP09_RS09710	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS09720	COG5265	(ABC) transporter
AZSP09_RS09725	COG2205	protein histidine kinase activity
AZSP09_RS09725	COG2202	Pas domain
AZSP09_RS09740	COG0203	ribosomal protein L17
AZSP09_RS09745	COG0202	RNA polymerase activity
AZSP09_RS09750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZSP09_RS09755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZSP09_RS09760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZSP09_RS09765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZSP09_RS09770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZSP09_RS09775	COG0201	protein transport
AZSP09_RS09780	COG0200	Binds to the 23S rRNA
AZSP09_RS09785	COG1841	ribosomal large subunit assembly
AZSP09_RS09790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZSP09_RS09795	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZSP09_RS09800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZSP09_RS09805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZSP09_RS09810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZSP09_RS09815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZSP09_RS09820	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZSP09_RS09830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZSP09_RS09835	COG0255	Belongs to the universal ribosomal protein uL29 family
AZSP09_RS09840	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZSP09_RS09845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZSP09_RS09850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZSP09_RS09855	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZSP09_RS09860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZSP09_RS09865	COG0089	rRNA binding
AZSP09_RS09870	COG0088	Forms part of the polypeptide exit tunnel
AZSP09_RS09875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZSP09_RS09880	COG0051	transcription antitermination factor activity, RNA binding
AZSP09_RS09885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZSP09_RS09890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZSP09_RS09895	COG0049	tRNA binding
AZSP09_RS09900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZSP09_RS09905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZSP09_RS09910	COG0085	RNA polymerase activity
AZSP09_RS09915	COG0222	ribosome binding
AZSP09_RS09920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZSP09_RS09925	COG0081	regulation of translation
AZSP09_RS09930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZSP09_RS09940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZSP09_RS09950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZSP09_RS09970	COG0277	FAD linked oxidase domain protein
AZSP09_RS09985	COG2198	Histidine kinase
AZSP09_RS09985	COG2205	protein histidine kinase activity
AZSP09_RS09985	COG0784	Response regulator, receiver
AZSP09_RS10000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZSP09_RS10010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_RS10015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZSP09_RS10020	COG0511	ligase activity, forming carbon-carbon bonds
AZSP09_RS10025	COG0439	Biotin carboxylase
AZSP09_RS10030	COG2264	protein methyltransferase activity
AZSP09_RS10050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZSP09_RS10070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AZSP09_RS10090	COG0859	PFAM glycosyl transferase family 9
AZSP09_RS10110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZSP09_RS10120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS10135	COG0601	transmembrane transport
AZSP09_RS10140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_RS10145	COG4608	Belongs to the ABC transporter superfamily
AZSP09_RS10165	COG0385	Bile acid
AZSP09_RS10180	COG3338	carbonate dehydratase activity
AZSP09_RS10185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZSP09_RS10190	COG0628	permease
AZSP09_RS10195	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AZSP09_RS10205	COG0583	DNA-binding transcription factor activity
AZSP09_RS10210	COG1902	pentaerythritol trinitrate reductase activity
AZSP09_RS10240	COG0826	peptidase U32
AZSP09_RS10245	COG1530	ribonuclease E activity
AZSP09_RS10255	COG0412	Dienelactone hydrolase
AZSP09_RS10260	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_RS10265	COG0791	NLP P60 protein
AZSP09_RS10280	COG2239	Acts as a magnesium transporter
AZSP09_RS10285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZSP09_RS10290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZSP09_RS10300	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AZSP09_RS10305	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AZSP09_RS10310	COG3150	esterase
AZSP09_RS10320	COG1968	undecaprenyl-diphosphatase activity
AZSP09_RS10325	COG0424	maF-like protein
AZSP09_RS10330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZSP09_RS10335	COG0799	negative regulation of ribosome biogenesis
AZSP09_RS10340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZSP09_RS10355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZSP09_RS10370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZSP09_RS10370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZSP09_RS10375	COG0859	PFAM glycosyl transferase family 9
AZSP09_RS10395	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS10410	COG0726	polysaccharide deacetylase
AZSP09_RS10415	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS10420	COG1132	(ABC) transporter
AZSP09_RS10425	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS10430	COG0859	PFAM glycosyl transferase family 9
AZSP09_RS10440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZSP09_RS10445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZSP09_RS10465	COG0602	queuosine metabolic process
AZSP09_RS10480	COG0823	Involved in the tonB-independent uptake of proteins
AZSP09_RS10500	COG0824	Thioesterase
AZSP09_RS10505	COG2255	four-way junction helicase activity
AZSP09_RS10510	COG0632	four-way junction helicase activity
AZSP09_RS10515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZSP09_RS10530	COG0217	transcriptional regulatory protein
AZSP09_RS10535	COG0433	COG0433 Predicted ATPase
AZSP09_RS10550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZSP09_RS10560	COG0129	dihydroxy-acid dehydratase activity
AZSP09_RS10570	COG1999	signal sequence binding
AZSP09_RS10575	COG0386	Belongs to the glutathione peroxidase family
AZSP09_RS10585	COG2703	oxygen carrier activity
AZSP09_RS10590	COG0840	transmembrane signaling receptor activity
AZSP09_RS10595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZSP09_RS10630	COG1022	Amp-dependent synthetase and ligase
AZSP09_RS10645	COG1703	isobutyryl-CoA mutase activity
AZSP09_RS10645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_RS10645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_RS10665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZSP09_RS10675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZSP09_RS10690	COG0067	glutamate synthase
AZSP09_RS10690	COG0069	glutamate synthase activity
AZSP09_RS10690	COG0070	glutamate synthase
AZSP09_RS10695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZSP09_RS10700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZSP09_RS10710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZSP09_RS10720	COG0840	transmembrane signaling receptor activity
AZSP09_RS10725	COG0004	ammonium transporteR
AZSP09_RS10730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZSP09_RS10740	COG0352	thiamine-phosphate diphosphorylase activity
AZSP09_RS10745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZSP09_RS10750	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AZSP09_RS10755	COG0237	dephospho-CoA kinase activity
AZSP09_RS10765	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AZSP09_RS10770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZSP09_RS10775	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZSP09_RS10775	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZSP09_RS10780	COG2204	response regulator
AZSP09_RS10785	COG3852	Histidine kinase
AZSP09_RS10795	COG0174	glutamine synthetase
AZSP09_RS10820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZSP09_RS10830	COG3568	Endonuclease Exonuclease Phosphatase
AZSP09_RS10835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZSP09_RS10840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_RS10845	COG0012	GTP binding
AZSP09_RS10850	COG0193	aminoacyl-tRNA hydrolase activity
AZSP09_RS10855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZSP09_RS10860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZSP09_RS10870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZSP09_RS10885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZSP09_RS10890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZSP09_RS10895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZSP09_RS10900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZSP09_RS10905	COG0742	ribosomal rna small subunit methyltransferase
AZSP09_RS10910	COG0612	Peptidase, M16
AZSP09_RS10915	COG0612	Peptidase, M16
AZSP09_RS10925	COG2884	Cell division ATP-binding protein ftsE
AZSP09_RS10930	COG2177	Part of the ABC transporter FtsEX involved in
AZSP09_RS10935	COG0415	Belongs to the DNA photolyase family
AZSP09_RS10945	COG1678	Uncharacterized ACR, COG1678
AZSP09_RS10950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZSP09_RS10955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZSP09_RS10960	COG0540	Belongs to the ATCase OTCase family
AZSP09_RS10975	COG3279	Response regulator of the LytR AlgR family
AZSP09_RS10980	COG1872	DUF167
AZSP09_RS10985	COG0762	integral membrane protein
AZSP09_RS11015	COG1981	membrane
AZSP09_RS11030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_RS11035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZSP09_RS11060	COG1136	(ABC) transporter
AZSP09_RS11060	COG0577	efflux transmembrane transporter activity
AZSP09_RS11085	COG1595	DNA-templated transcription, initiation
AZSP09_RS11105	COG2151	metal-sulfur cluster biosynthetic enzyme
AZSP09_RS11135	COG4654	Cytochrome c, class I
AZSP09_RS11140	COG1331	Highly conserved protein containing a thioredoxin domain
AZSP09_RS11145	COG0583	DNA-binding transcription factor activity
AZSP09_RS11150	COG0697	spore germination
AZSP09_RS11160	COG0765	amino acid transport
AZSP09_RS11165	COG0765	amino acid transport
AZSP09_RS11170	COG1126	abc transporter atp-binding protein
AZSP09_RS11180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZSP09_RS11190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZSP09_RS11200	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS11205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZSP09_RS11215	COG1560	Kdo2-lipid A biosynthetic process
AZSP09_RS11225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZSP09_RS11235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AZSP09_RS11255	COG3647	Membrane
AZSP09_RS11260	COG2198	Histidine kinase
AZSP09_RS11260	COG0784	Response regulator, receiver
AZSP09_RS11260	COG0643	Histidine kinase
AZSP09_RS11290	COG0351	phosphomethylpyrimidine kinase
AZSP09_RS11295	COG0352	thiamine-phosphate diphosphorylase activity
AZSP09_RS11300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZSP09_RS11305	COG3152	Membrane
AZSP09_RS11310	COG2326	polyphosphate kinase activity
AZSP09_RS11345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZSP09_RS11350	COG0018	arginyl-trna synthetase
AZSP09_RS11360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZSP09_RS11380	COG1999	signal sequence binding
AZSP09_RS11390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_RS11395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZSP09_RS11400	COG0741	lytic transglycosylase activity
AZSP09_RS11415	COG0617	tRNA 3'-terminal CCA addition
AZSP09_RS11425	COG0625	glutathione transferase activity
AZSP09_RS11460	COG0037	tRNA processing
AZSP09_RS11465	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZSP09_RS11470	COG0515	serine threonine protein kinase
AZSP09_RS11470	COG2815	serine threonine protein kinase
AZSP09_RS11495	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZSP09_RS11505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZSP09_RS11510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZSP09_RS11515	COG1137	ATPase activity
AZSP09_RS11520	COG2137	regulation of response to DNA damage stimulus
AZSP09_RS11525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZSP09_RS11535	COG2193	ferroxidase activity
AZSP09_RS11540	COG1546	Belongs to the CinA family
AZSP09_RS11545	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZSP09_RS11555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_RS11560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZSP09_RS11575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZSP09_RS11580	COG4232	protein-disulfide reductase activity
AZSP09_RS11610	COG1131	(ABC) transporter
AZSP09_RS11620	COG3411	Ferredoxin
AZSP09_RS11630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZSP09_RS11635	COG1238	metal cluster binding
AZSP09_RS11645	COG0432	Pfam Uncharacterised protein family UPF0047
AZSP09_RS11650	COG2223	nitrite transmembrane transporter activity
AZSP09_RS11655	COG2813	Specifically methylates the guanine in position
AZSP09_RS11655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZSP09_RS11660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZSP09_RS11665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZSP09_RS11670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZSP09_RS11685	COG0189	ligase activity
AZSP09_RS11715	COG0488	(ABC) transporter
AZSP09_RS11730	COG0488	(ABC) transporter
AZSP09_RS11740	COG5002	protein histidine kinase activity
AZSP09_RS11740	COG5001	Diguanylate cyclase
AZSP09_RS11755	COG0004	ammonium transporteR
AZSP09_RS11770	COG2960	long-chain fatty acid transporting porin activity
AZSP09_RS11780	COG2814	Major facilitator Superfamily
AZSP09_RS11800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_RS11820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZSP09_RS11830	COG3876	Protein conserved in bacteria
AZSP09_RS11855	COG3706	GGDEF domain
AZSP09_RS11855	COG5001	Diguanylate cyclase
AZSP09_RS11855	COG4251	negative regulation of phosphorylation
AZSP09_RS11855	COG2203	Gaf domain
AZSP09_RS11860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZSP09_RS11900	COG0288	reversible hydration of carbon dioxide
AZSP09_RS11915	COG1940	carbohydrate kinase activity
AZSP09_RS11920	COG2258	MOSC domain
AZSP09_RS11935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZSP09_RS11940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZSP09_RS11950	COG0569	domain protein
AZSP09_RS11955	COG2204	response regulator
AZSP09_RS11970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZSP09_RS11970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_RS11975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZSP09_RS11985	COG0501	Belongs to the peptidase M48B family
AZSP09_RS11990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZSP09_RS11995	COG0242	peptide deformylase activity
AZSP09_RS12005	COG0758	DNA mediated transformation
AZSP09_RS12010	COG2922	Belongs to the Smg family
AZSP09_RS12020	COG0783	Belongs to the Dps family
AZSP09_RS12025	COG0583	DNA-binding transcription factor activity
AZSP09_RS12030	COG1187	pseudouridine synthase activity
AZSP09_RS12045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZSP09_RS12045	COG2755	lipolytic protein G-D-S-L family
AZSP09_RS12055	COG3586	endonuclease activity
AZSP09_RS12075	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AZSP09_RS12090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZSP09_RS12095	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZSP09_RS12100	COG0594	ribonuclease P activity
AZSP09_RS12105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZSP09_RS12110	COG0706	membrane insertase activity
AZSP09_RS12115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZSP09_RS12160	COG0445	tRNA wobble uridine modification
AZSP09_RS12165	COG0357	Ribosomal RNA small subunit methyltransferase G
AZSP09_RS12170	COG1192	Involved in chromosome partitioning
AZSP09_RS12175	COG1475	DNA binding
AZSP09_RS12185	COG0356	it plays a direct role in the translocation of protons across the membrane
AZSP09_RS12195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZSP09_RS12200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZSP09_RS12205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZSP09_RS12210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZSP09_RS12215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZSP09_RS12220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZSP09_RS12235	COG2226	methyltransferase
AZSP09_RS12245	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS12250	COG5002	protein histidine kinase activity
AZSP09_RS12290	COG0708	Exodeoxyribonuclease III
AZSP09_RS12295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZSP09_RS12315	COG0348	domain, Protein
AZSP09_RS12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_RS12350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZSP09_RS12360	COG0154	amidase activity
AZSP09_RS12365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZSP09_RS12370	COG1077	Cell shape determining protein MreB Mrl
AZSP09_RS12375	COG1792	Involved in formation and maintenance of cell shape
AZSP09_RS12380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AZSP09_RS12385	COG0768	penicillin binding
AZSP09_RS12390	COG0772	Belongs to the SEDS family
AZSP09_RS12425	COG1686	Belongs to the peptidase S11 family
AZSP09_RS12430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZSP09_RS12435	COG2921	Belongs to the UPF0250 family
AZSP09_RS12440	COG0321	lipoyl(octanoyl) transferase activity
AZSP09_RS12445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZSP09_RS12490	COG2129	metallophosphoesterase
AZSP09_RS12540	COG3437	response regulator, receiver
AZSP09_RS12550	COG5002	protein histidine kinase activity
AZSP09_RS12550	COG2205	protein histidine kinase activity
AZSP09_RS12550	COG0784	Response regulator, receiver
AZSP09_RS12575	COG0114	fumarate hydratase activity
AZSP09_RS12585	COG0348	domain, Protein
AZSP09_RS12595	COG2204	response regulator
AZSP09_RS12610	COG0210	DNA helicase
AZSP09_RS12620	COG3245	cytochrome
AZSP09_RS12665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZSP09_RS12670	COG0316	Belongs to the HesB IscA family
AZSP09_RS12695	COG2030	dehydratase
AZSP09_RS12715	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZSP09_RS12725	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_RS12750	COG0826	peptidase U32
AZSP09_RS12755	COG0826	peptidase U32
AZSP09_RS12760	COG3154	lipid carrier protein
AZSP09_RS12775	COG1515	deoxyribonuclease V activity
AZSP09_RS12790	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_RS12810	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS12815	COG0183	Belongs to the thiolase family
AZSP09_RS12820	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS12830	COG1408	metallophosphoesterase
AZSP09_RS12840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZSP09_RS12845	COG1024	Enoyl-CoA hydratase
AZSP09_RS12855	COG5001	Diguanylate cyclase
AZSP09_RS12875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_RS12885	COG1473	amidohydrolase
AZSP09_RS12890	COG1660	Displays ATPase and GTPase activities
AZSP09_RS12920	COG0741	lytic transglycosylase activity
AZSP09_RS12930	COG1194	a g-specific adenine glycosylase
AZSP09_RS12935	COG0714	Associated with various cellular activities
AZSP09_RS12955	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AZSP09_RS12960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZSP09_RS12975	COG0582	viral genome integration into host DNA
AZSP09_RS13035	COG2003	Belongs to the UPF0758 family
AZSP09_RS13095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZSP09_RS13120	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZSP09_RS13235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZSP09_RS13280	COG1192	Involved in chromosome partitioning
AZSP09_RS13295	COG0583	DNA-binding transcription factor activity
AZSP09_RS13315	COG0071	Belongs to the small heat shock protein (HSP20) family
AZSP09_RS13320	COG0542	response to heat
AZSP09_RS13330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_RS13350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_RS13355	COG0583	DNA-binding transcription factor activity
AZSP09_RS13360	COG0583	DNA-binding transcription factor activity
AZSP09_RS13400	COG2022	thiamine diphosphate biosynthetic process
AZSP09_RS13410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZSP09_RS13430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZSP09_RS13435	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZSP09_RS13450	COG1121	(ABC) transporter
AZSP09_RS13455	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZSP09_RS13470	COG0523	cobalamin synthesis protein
AZSP09_RS13475	COG0523	cobalamin synthesis protein
AZSP09_RS13520	COG3411	Ferredoxin
AZSP09_RS13535	COG3447	MASE1 domain protein
AZSP09_RS13535	COG5001	Diguanylate cyclase
AZSP09_RS13535	COG5002	protein histidine kinase activity
AZSP09_RS13600	COG2824	Alkylphosphonate utilization operon protein PhnA
AZSP09_RS13615	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
AZSP09_RS13625	COG5420	small protein containing a coiled-coil domain
AZSP09_RS13640	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_RS13645	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_RS13650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZSP09_RS13655	COG2391	methyltransferase activity
AZSP09_RS13685	COG1492	cobalamin metabolic process
AZSP09_RS13700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_RS13730	COG1797	cobyrinic acid a,c-diamide synthase activity
AZSP09_RS13740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZSP09_RS13745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZSP09_RS13750	COG4774	siderophore transport
AZSP09_RS13775	COG0730	response to heat
AZSP09_RS13780	COG3162	membrane
AZSP09_RS13785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZSP09_RS13790	COG1024	Enoyl-CoA hydratase
AZSP09_RS13795	COG1802	Transcriptional regulator
AZSP09_RS13800	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_RS13800	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_RS13805	COG1703	isobutyryl-CoA mutase activity
AZSP09_RS13810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZSP09_RS13815	COG4770	biotin carboxylase activity
AZSP09_RS13840	COG2129	metallophosphoesterase
AZSP09_RS13855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZSP09_RS13900	COG0348	domain, Protein
AZSP09_RS13905	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_RS13910	COG0243	molybdopterin cofactor binding
AZSP09_RS13925	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZSP09_RS13925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZSP09_RS13930	COG3781	membrane
AZSP09_RS13935	COG0084	hydrolase, TatD family'
AZSP09_RS13940	COG1024	Enoyl-CoA hydratase
AZSP09_RS13945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZSP09_RS13950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZSP09_RS13955	COG1758	RNA polymerase activity
AZSP09_RS13960	COG0194	GDP metabolic process
AZSP09_RS13965	COG1561	YicC-like family, N-terminal region
AZSP09_RS13970	COG0515	serine threonine protein kinase
AZSP09_RS13970	COG2815	serine threonine protein kinase
AZSP09_RS13975	COG0631	protein serine/threonine phosphatase activity
AZSP09_RS13980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZSP09_RS13990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZSP09_RS13995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZSP09_RS14045	COG2814	Major facilitator Superfamily
AZSP09_RS14115	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AZSP09_RS14120	COG4191	Histidine kinase
AZSP09_RS14130	COG0501	Belongs to the peptidase M48B family
AZSP09_RS14140	COG0583	DNA-binding transcription factor activity
AZSP09_RS14155	COG2204	response regulator
AZSP09_RS14160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZSP09_RS14160	COG1024	Enoyl-CoA hydratase
AZSP09_RS14175	COG0309	Hydrogenase expression formation protein (HypE)
AZSP09_RS14180	COG0409	Hydrogenase expression formation protein
AZSP09_RS14185	COG0298	carbon dioxide binding
AZSP09_RS14195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZSP09_RS14205	COG0375	protein maturation
AZSP09_RS14215	COG1858	cytochrome C peroxidase
AZSP09_RS14220	COG4133	protoheme IX ABC transporter activity
AZSP09_RS14225	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_RS14235	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_RS14240	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZSP09_RS14250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_RS14285	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZSP09_RS14290	COG4191	Histidine kinase
AZSP09_RS14295	COG0019	diaminopimelate decarboxylase activity
AZSP09_RS14300	COG1965	Belongs to the frataxin family
AZSP09_RS14305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AZSP09_RS14320	COG1484	DNA-dependent DNA replication
AZSP09_RS14325	COG4584	PFAM Integrase catalytic
AZSP09_RS14345	COG3039	Transposase
AZSP09_RS14350	COG4585	Histidine kinase
AZSP09_RS14355	COG2197	response regulator
AZSP09_RS14360	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS14370	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_RS14370	COG1024	Enoyl-CoA hydratase
AZSP09_RS14375	COG0183	Belongs to the thiolase family
AZSP09_RS14380	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS14400	COG2030	dehydratase
AZSP09_RS14440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZSP09_RS14445	COG1702	phosphate starvation-inducible protein PhoH
AZSP09_RS14450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZSP09_RS14455	COG4535	Mg2 and Co2 transporter CorC
AZSP09_RS14460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZSP09_RS14465	COG0752	glycyl-tRNA synthetase alpha subunit
AZSP09_RS14470	COG0751	glycine-tRNA ligase activity
AZSP09_RS14475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZSP09_RS14580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZSP09_RS14585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZSP09_RS14600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZSP09_RS14615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZSP09_RS14620	COG4974	Belongs to the 'phage' integrase family
AZSP09_RS14635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZSP09_RS14645	COG1466	dna polymerase III delta subunit
AZSP09_RS14655	COG0495	leucyl-tRNA aminoacylation
AZSP09_RS14670	COG0210	DNA helicase
AZSP09_RS14695	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_RS14700	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_RS14705	COG0312	modulator of DNA gyrase
AZSP09_RS14710	COG3028	Belongs to the UPF0307 family
AZSP09_RS14715	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZSP09_RS14725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZSP09_RS14730	COG0166	Belongs to the GPI family
AZSP09_RS14745	COG0717	Belongs to the dCTP deaminase family
AZSP09_RS14750	COG0489	protein tyrosine kinase activity
AZSP09_RS14755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_RS14755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_RS14765	COG0659	secondary active sulfate transmembrane transporter activity
AZSP09_RS14770	COG1254	Belongs to the acylphosphatase family
AZSP09_RS14780	COG0450	alkyl hydroperoxide reductase
AZSP09_RS14785	COG4771	TonB-dependent receptor
AZSP09_RS14820	COG0463	Glycosyl transferase, family 2
AZSP09_RS14830	COG0583	DNA-binding transcription factor activity
AZSP09_RS14835	COG1741	Belongs to the pirin family
AZSP09_RS14845	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS14865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_RS14870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_RS14875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZSP09_RS14875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZSP09_RS14880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZSP09_RS14890	COG0793	Belongs to the peptidase S41A family
AZSP09_RS14895	COG4942	peptidase
AZSP09_RS14905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZSP09_RS14915	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZSP09_RS14925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZSP09_RS14930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZSP09_RS14935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_RS14940	COG1459	type II secretion system
AZSP09_RS14950	COG2165	general secretion pathway protein
AZSP09_RS14955	COG2165	general secretion pathway protein
AZSP09_RS15005	COG1450	Type ii and iii secretion system protein
AZSP09_RS15010	COG3409	Peptidoglycan-binding domain 1 protein
AZSP09_RS15010	COG3267	Type II secretory pathway component ExeA
AZSP09_RS15020	COG3307	-O-antigen
AZSP09_RS15030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZSP09_RS15035	COG2226	methyltransferase
AZSP09_RS15040	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZSP09_RS15045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_RS15070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZSP09_RS15090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZSP09_RS15095	COG0071	Belongs to the small heat shock protein (HSP20) family
AZSP09_RS15105	COG0494	nUDIX hydrolase
AZSP09_RS15110	COG2732	(Barnase) inhibitor
AZSP09_RS15120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZSP09_RS15135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AZSP09_RS15150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_RS15155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZSP09_RS15160	COG0741	lytic transglycosylase activity
AZSP09_RS15165	COG0442	prolyl-tRNA aminoacylation
AZSP09_RS15170	COG0494	nUDIX hydrolase
AZSP09_RS15185	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AZSP09_RS15190	COG1765	OsmC-like protein
AZSP09_RS15195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZSP09_RS15200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZSP09_RS15215	COG0316	Belongs to the HesB IscA family
AZSP09_RS15220	COG4942	peptidase
AZSP09_RS15220	COG1388	LysM domain
AZSP09_RS15275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZSP09_RS15285	COG0596	Alpha beta hydrolase
AZSP09_RS15295	COG0598	Magnesium transport protein CorA
AZSP09_RS15300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZSP09_RS15310	COG2703	oxygen carrier activity
AZSP09_RS15325	COG0513	Belongs to the DEAD box helicase family
AZSP09_RS15330	COG2030	dehydratase
AZSP09_RS15340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_RS15355	COG0739	heme binding
AZSP09_RS15360	COG0284	orotidine-5'-phosphate decarboxylase activity
AZSP09_RS15370	COG5001	Diguanylate cyclase
AZSP09_RS15370	COG5002	protein histidine kinase activity
AZSP09_RS15370	COG3447	MASE1 domain protein
AZSP09_RS15395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_RS15400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZSP09_RS15410	COG0583	DNA-binding transcription factor activity
AZSP09_RS15415	COG0840	transmembrane signaling receptor activity
AZSP09_RS15420	COG1643	Atp-dependent helicase
AZSP09_RS15445	COG1024	Enoyl-CoA hydratase
AZSP09_RS15450	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AZSP09_RS15460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AZSP09_RS15520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_RS15535	COG3409	Peptidoglycan-binding domain 1 protein
AZSP09_RS15535	COG3267	Type II secretory pathway component ExeA
AZSP09_RS15540	COG2204	response regulator
AZSP09_RS15545	COG1127	ABC transporter
AZSP09_RS15550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZSP09_RS15555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZSP09_RS15560	COG2853	Lipoprotein
AZSP09_RS15570	COG3113	response to antibiotic
AZSP09_RS15575	COG1131	(ABC) transporter
AZSP09_RS15580	COG0842	Transport permease protein
AZSP09_RS15585	COG5007	Belongs to the BolA IbaG family
AZSP09_RS15590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZSP09_RS15605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZSP09_RS15610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZSP09_RS15625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZSP09_RS15630	COG0131	Imidazoleglycerol-phosphate dehydratase
AZSP09_RS15635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZSP09_RS15640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZSP09_RS15645	COG0107	imidazoleglycerol-phosphate synthase activity
AZSP09_RS15650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZSP09_RS15655	COG0140	phosphoribosyl-ATP diphosphatase activity
AZSP09_RS15665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZSP09_RS15670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZSP09_RS15680	COG0121	glutamine amidotransferase
AZSP09_RS15685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_RS15690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZSP09_RS15705	COG2203	Gaf domain
AZSP09_RS15705	COG3706	GGDEF domain
AZSP09_RS15705	COG5001	Diguanylate cyclase
AZSP09_RS15705	COG4251	negative regulation of phosphorylation
AZSP09_RS15715	COG2201	protein-glutamate methylesterase activity
AZSP09_RS15720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_RS15725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZSP09_RS15730	COG0835	chemotaxis
AZSP09_RS15735	COG0840	transmembrane signaling receptor activity
AZSP09_RS15740	COG2198	Histidine kinase
AZSP09_RS15740	COG0643	Histidine kinase
AZSP09_RS15755	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS15765	COG0534	Mate efflux family protein
AZSP09_RS15780	COG0045	succinate-CoA ligase (ADP-forming) activity
AZSP09_RS15785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZSP09_RS15790	COG0861	Integral membrane protein TerC family
AZSP09_RS15800	COG0515	serine threonine protein kinase
AZSP09_RS15800	COG2815	serine threonine protein kinase
AZSP09_RS15805	COG0631	protein serine/threonine phosphatase activity
AZSP09_RS15825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS15830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_RS15835	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_RS15860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_RS15865	COG1136	(ABC) transporter
AZSP09_RS15870	COG3284	Transcriptional regulator
AZSP09_RS15875	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_RS15905	COG1136	(ABC) transporter
AZSP09_RS15905	COG0577	efflux transmembrane transporter activity
AZSP09_RS15915	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AZSP09_RS15920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZSP09_RS15925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZSP09_RS15930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZSP09_RS15935	COG0840	transmembrane signaling receptor activity
AZSP09_RS15990	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_RS16010	COG0617	tRNA 3'-terminal CCA addition
AZSP09_RS16025	COG0628	permease
AZSP09_RS16030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZSP09_RS16035	COG4654	Cytochrome c, class I
AZSP09_RS16045	COG0515	serine threonine protein kinase
AZSP09_RS16045	COG2815	serine threonine protein kinase
AZSP09_RS16050	COG2814	Major facilitator Superfamily
AZSP09_RS16055	COG1846	Transcriptional regulator
AZSP09_RS16060	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZSP09_RS16075	COG2205	protein histidine kinase activity
AZSP09_RS16080	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS16100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZSP09_RS16105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZSP09_RS16110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZSP09_RS16120	COG2003	Belongs to the UPF0758 family
AZSP09_RS16125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZSP09_RS16130	COG0756	dUTP diphosphatase activity
AZSP09_RS16135	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZSP09_RS16145	COG1196	nuclear chromosome segregation
AZSP09_RS16145	COG3264	Mechanosensitive ion channel
AZSP09_RS16150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_RS16150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZSP09_RS16160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZSP09_RS16170	COG0586	Pfam SNARE associated Golgi protein
AZSP09_RS16175	COG0784	Response regulator, receiver
AZSP09_RS16180	COG4251	negative regulation of phosphorylation
AZSP09_RS16185	COG5001	Diguanylate cyclase
AZSP09_RS16190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZSP09_RS16200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZSP09_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_RS16225	COG0126	phosphoglycerate kinase activity
AZSP09_RS16230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZSP09_RS16240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZSP09_RS16245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZSP09_RS16255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZSP09_RS16265	COG5001	Diguanylate cyclase
AZSP09_RS16265	COG5002	protein histidine kinase activity
AZSP09_RS16280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZSP09_RS16290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZSP09_RS16290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AZSP09_RS16295	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AZSP09_RS16305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZSP09_RS16315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZSP09_RS16320	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_RS16325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AZSP09_RS16340	COG4566	intracellular signal transduction
AZSP09_RS16345	COG0247	lactate metabolic process
AZSP09_RS16350	COG1139	Iron-sulfur cluster binding protein
AZSP09_RS16355	COG1556	Lactate utilization protein
AZSP09_RS16360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZSP09_RS16365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_RS16370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZSP09_RS16390	COG0006	proline dipeptidase activity
AZSP09_RS16395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZSP09_RS16415	COG0151	Belongs to the GarS family
AZSP09_RS16420	COG0408	coproporphyrinogen oxidase activity
AZSP09_RS16435	COG2959	enzyme of heme biosynthesis
AZSP09_RS16445	COG0181	hydroxymethylbilane synthase activity
AZSP09_RS16450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZSP09_RS16465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_RS16530	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS16535	COG0642	Histidine kinase
AZSP09_RS16540	COG2194	sulfuric ester hydrolase activity
AZSP09_RS16550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AZSP09_RS16570	COG2217	Heavy metal translocating P-type atpase
AZSP09_RS16580	COG3278	Belongs to the heme-copper respiratory oxidase family
AZSP09_RS16620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZSP09_RS16625	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_RS16670	COG3945	hemerythrin HHE cation binding domain
AZSP09_RS16675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_RS16680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZSP09_RS16695	COG2217	Heavy metal translocating P-type atpase
AZSP09_RS16725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZSP09_RS16725	COG1918	ferrous iron import across plasma membrane
AZSP09_RS16735	COG0672	)-iron permease
AZSP09_RS16740	COG4633	Protein conserved in bacteria
AZSP09_RS16820	COG3128	pkhd-type hydroxylase
AZSP09_RS16825	COG4774	siderophore transport
AZSP09_RS16835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_RS16840	COG1858	cytochrome C peroxidase
AZSP09_RS16845	COG4771	TonB-dependent receptor
AZSP09_RS16875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZSP09_RS16885	COG1429	ligase activity, forming nitrogen-metal bonds
AZSP09_RS16890	COG4771	TonB-dependent receptor
AZSP09_RS16915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZSP09_RS16920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZSP09_RS16920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZSP09_RS16925	COG0347	Belongs to the P(II) protein family
AZSP09_RS16930	COG2840	Smr protein MutS2
AZSP09_RS16935	COG0492	ferredoxin-NADP+ reductase activity
AZSP09_RS16945	COG1674	ftsk spoiiie
AZSP09_RS16950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZSP09_RS16965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZSP09_RS16975	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZSP09_RS16980	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AZSP09_RS17060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZSP09_RS17065	COG1360	Flagellar Motor Protein
AZSP09_RS17075	COG0745	RESPONSE REGULATOR receiver
AZSP09_RS17080	COG2198	Histidine kinase
AZSP09_RS17080	COG0643	Histidine kinase
AZSP09_RS17085	COG0835	chemotaxis
AZSP09_RS17090	COG0840	transmembrane signaling receptor activity
AZSP09_RS17090	COG0840	transmembrane signaling receptor activity
AZSP09_RS17095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZSP09_RS17100	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_RS17105	COG2201	protein-glutamate methylesterase activity
AZSP09_RS17120	COG0840	transmembrane signaling receptor activity
AZSP09_RS17125	COG0784	Response regulator, receiver
AZSP09_RS17125	COG0835	chemotaxis
AZSP09_RS17130	COG0835	chemotaxis
AZSP09_RS17130	COG0784	Response regulator, receiver
AZSP09_RS17140	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZSP09_RS17145	COG2198	Histidine kinase
AZSP09_RS17145	COG0784	Response regulator, receiver
AZSP09_RS17145	COG0643	Histidine kinase
AZSP09_RS17175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZSP09_RS17205	COG1558	bacterial-type flagellum-dependent cell motility
AZSP09_RS17215	COG1749	Flagellar hook protein flgE
AZSP09_RS17220	COG4787	bacterial-type flagellum-dependent cell motility
AZSP09_RS17230	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZSP09_RS17235	COG1706	bacterial-type flagellum-dependent cell motility
AZSP09_RS17275	COG3190	flagellar
AZSP09_RS17280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZSP09_RS17285	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZSP09_RS17295	COG3144	bacterial-type flagellum assembly
AZSP09_RS17305	COG1157	protein secretion by the type III secretion system
AZSP09_RS17325	COG0784	Response regulator, receiver
AZSP09_RS17325	COG2205	protein histidine kinase activity
AZSP09_RS17335	COG1677	Flagellar hook-basal body complex protein FliE
AZSP09_RS17340	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AZSP09_RS17345	COG2257	FlhB HrpN YscU SpaS Family
AZSP09_RS17375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZSP09_RS17380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZSP09_RS17395	COG1216	Glycosyl transferase, family 2
AZSP09_RS17395	COG0438	transferase activity, transferring glycosyl groups
AZSP09_RS17400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZSP09_RS17435	COG1215	transferase activity, transferring glycosyl groups
AZSP09_RS17455	COG0022	dehydrogenase e1 component
AZSP09_RS17460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZSP09_RS17465	COG0859	PFAM glycosyl transferase family 9
AZSP09_RS17485	COG0582	viral genome integration into host DNA
AZSP09_RS17570	COG1309	transcriptional regulator
AZSP09_RS17595	COG0776	regulation of translation
AZSP09_RS17610	COG1414	Transcriptional regulator
AZSP09_RS17680	COG4804	nuclease activity
AZSP09_RS17820	COG1396	sequence-specific DNA binding
AZSP09_RS17820	COG3800	Transcriptional regulator
AZSP09_RS17840	COG1607	acyl-coa hydrolase
AZSP09_RS17850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZSP09_RS17855	COG1802	Transcriptional regulator
AZSP09_RS17860	COG0583	DNA-binding transcription factor activity
AZSP09_RS17865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZSP09_RS17870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_RS17890	COG1120	ATPase activity
AZSP09_RS17900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_RS17915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_RS17915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_RS17930	COG0602	queuosine metabolic process
AZSP09_RS17935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_RS17945	COG4644	lycopene metabolic process
AZSP09_RS17970	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZSP09_RS18020	COG1674	ftsk spoiiie
AZSP09_RS18145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZSP09_RS18375	COG0592	DNA-directed DNA polymerase activity
AZSP09_RS18460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZSP09_RS18600	COG1199	ATP-dependent helicase activity
AZSP09_RS18705	COG4680	protein conserved in bacteria
AZSP09_RS18920	COG0322	excinuclease ABC activity
AZSP09_RS18970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZSP09_RS19085	COG0463	Glycosyl transferase, family 2
AZSP09_RS19090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZSP09_RS19205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZSP09_RS19285	COG4585	Histidine kinase
AZSP09_RS19310	COG3541	Predicted nucleotidyltransferase
AZSP09_RS19315	COG4804	nuclease activity
AZSP09_RS19325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZSP09_RS19370	COG0629	single-stranded DNA binding
AZSP09_RS19410	COG2894	cell division
AZSP09_RS19440	COG2974	May be involved in recombination
AZSP09_RS19490	COG0739	heme binding
AZSP09_RS19520	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
AZSP09_RS19575	COG3451	type IV secretory pathway VirB4
AZSP09_RS19585	COG3838	Conjugal transfer protein Trbc
AZSP09_RS19590	COG4962	Type ii secretion system protein e
AZSP09_RS19610	COG0583	DNA-binding transcription factor activity
AZSP09_RS19635	COG2076	Multidrug Resistance protein
AZSP09_RS19655	COG4372	Transposase
AZSP09_RS19680	COG4959	Type IV secretory pathway protease TraF
AZSP09_RS19695	COG1192	Involved in chromosome partitioning
AZSP09_RS19735	COG5489	Protein of unknown function (DUF736)
AZSP09_RS19760	COG3077	Addiction module antitoxin, RelB DinJ family
AZSP09_RS19770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZSP09_RS19780	COG1484	DNA-dependent DNA replication
AZSP09_RS19785	COG4584	PFAM Integrase catalytic
AZSP09_RS19805	COG3039	Transposase
AZSP09_RS19810	COG4585	Histidine kinase
AZSP09_RS19815	COG2197	response regulator
AZSP09_RS19820	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_RS19830	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_RS19830	COG1024	Enoyl-CoA hydratase
AZSP09_RS19835	COG0183	Belongs to the thiolase family
AZSP09_RS19840	COG1960	acyl-CoA dehydrogenase activity
AZSP09_RS19860	COG2030	dehydratase