locus-tag	class	description
D3093_RS00040	COG0114	fumarate hydratase activity
D3093_RS00060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3093_RS00075	COG0205	6-phosphofructokinase activity
D3093_RS00105	COG0288	reversible hydration of carbon dioxide
D3093_RS00120	COG3321	synthase
D3093_RS00120	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS00120	COG0604	alcohol dehydrogenase
D3093_RS00145	COG2960	long-chain fatty acid transporting porin activity
D3093_RS00165	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS00175	COG0840	transmembrane signaling receptor activity
D3093_RS00195	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3093_RS00200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3093_RS00205	COG0343	queuine tRNA-ribosyltransferase activity
D3093_RS00210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3093_RS00215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3093_RS00260	COG2897	thiosulfate sulfurtransferase activity
D3093_RS00280	COG3903	Transcriptional regulator
D3093_RS00280	COG3629	intracellular signal transduction
D3093_RS00360	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3093_RS00365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3093_RS00370	COG0242	peptide deformylase activity
D3093_RS00380	COG3070	regulator of competence-specific genes
D3093_RS00395	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
D3093_RS00420	COG4120	Belongs to the binding-protein-dependent transport system permease family
D3093_RS00435	COG0489	protein tyrosine kinase activity
D3093_RS00440	COG0330	HflC and HflK could
D3093_RS00445	COG0330	HflC and HflK could
D3093_RS00470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3093_RS00475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3093_RS00480	COG0028	Belongs to the TPP enzyme family
D3093_RS00495	COG0704	Plays a role in the regulation of phosphate uptake
D3093_RS00500	COG2862	Uncharacterized protein family, UPF0114
D3093_RS00520	COG0768	penicillin binding
D3093_RS00540	COG1744	ABC transporter substrate-binding protein PnrA-like
D3093_RS00545	COG3845	ABC transporter
D3093_RS00550	COG4603	Belongs to the binding-protein-dependent transport system permease family
D3093_RS00555	COG1079	Belongs to the binding-protein-dependent transport system permease family
D3093_RS00560	COG0295	cytidine deaminase activity
D3093_RS00565	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3093_RS00570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3093_RS00585	COG0697	spore germination
D3093_RS00620	COG0038	chloride channel
D3093_RS00630	COG2326	polyphosphate kinase activity
D3093_RS00635	COG0366	Alpha amylase catalytic
D3093_RS00645	COG2200	EAL domain
D3093_RS00645	COG2199	diguanylate cyclase activity
D3093_RS00645	COG2203	Gaf domain
D3093_RS00655	COG2135	peptidase activity
D3093_RS00665	COG0784	Response regulator, receiver
D3093_RS00670	COG2261	transglycosylase associated protein
D3093_RS00675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3093_RS00690	COG1733	regulation of RNA biosynthetic process
D3093_RS00705	COG2084	Dehydrogenase
D3093_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS00725	COG0546	phosphoglycolate phosphatase activity
D3093_RS00740	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3093_RS00750	COG2832	Protein of unknown function (DUF454)
D3093_RS00755	COG1238	metal cluster binding
D3093_RS00760	COG3852	Histidine kinase
D3093_RS00765	COG0469	pyruvate kinase activity
D3093_RS00770	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3093_RS00785	COG0203	ribosomal protein L17
D3093_RS00790	COG1238	metal cluster binding
D3093_RS00805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3093_RS00820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3093_RS00825	COG0564	pseudouridine synthase activity
D3093_RS00830	COG1802	Transcriptional regulator
D3093_RS00835	COG3135	benzoate transporter
D3093_RS00840	COG0546	phosphoglycolate phosphatase activity
D3093_RS00860	COG0354	folic acid binding
D3093_RS00865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3093_RS00870	COG3845	ABC transporter
D3093_RS00875	COG4603	Belongs to the binding-protein-dependent transport system permease family
D3093_RS00880	COG1079	Belongs to the binding-protein-dependent transport system permease family
D3093_RS00920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D3093_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS00940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3093_RS00945	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
D3093_RS00955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3093_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3093_RS00965	COG0351	phosphomethylpyrimidine kinase
D3093_RS00970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3093_RS00985	COG0670	Belongs to the BI1 family
D3093_RS01005	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS01005	COG2030	dehydratase
D3093_RS01010	COG0443	Heat shock 70 kDa protein
D3093_RS01035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3093_RS01035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D3093_RS01090	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3093_RS01095	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3093_RS01105	COG0649	NAD binding
D3093_RS01110	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D3093_RS01120	COG1034	ATP synthesis coupled electron transport
D3093_RS01125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D3093_RS01130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3093_RS01140	COG0713	ATP synthesis coupled electron transport
D3093_RS01155	COG1007	ATP synthesis coupled electron transport
D3093_RS01175	COG0346	lactoylglutathione lyase activity
D3093_RS01185	COG0519	Catalyzes the synthesis of GMP from XMP
D3093_RS01200	COG0442	prolyl-tRNA aminoacylation
D3093_RS01245	COG0052	Belongs to the universal ribosomal protein uS2 family
D3093_RS01250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3093_RS01255	COG0528	UMP kinase activity
D3093_RS01260	COG0233	cytoplasmic translational termination
D3093_RS01265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3093_RS01275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3093_RS01280	COG0750	zinc metalloprotease
D3093_RS01300	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3093_RS01305	COG3494	Protein of unknown function (DUF1009)
D3093_RS01310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3093_RS01325	COG0583	DNA-binding transcription factor activity
D3093_RS01340	COG0372	Belongs to the citrate synthase family
D3093_RS01345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3093_RS01350	COG0658	competence protein
D3093_RS01350	COG2333	competence protein COMEC
D3093_RS01355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D3093_RS01360	COG0303	'Molybdopterin
D3093_RS01365	COG0315	cyclic pyranopterin monophosphate synthase activity
D3093_RS01410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3093_RS01420	COG0149	triose-phosphate isomerase activity
D3093_RS01450	COG0535	radical SAM domain protein
D3093_RS01455	COG0535	radical SAM domain protein
D3093_RS01460	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
D3093_RS01465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3093_RS01475	COG0148	phosphopyruvate hydratase activity
D3093_RS01485	COG0037	tRNA processing
D3093_RS01505	COG0678	peroxiredoxin activity
D3093_RS01520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS01540	COG0596	Alpha beta hydrolase
D3093_RS01545	COG0728	peptidoglycan biosynthetic process
D3093_RS01555	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3093_RS01590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS01595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS01610	COG0745	RESPONSE REGULATOR receiver
D3093_RS01620	COG0745	RESPONSE REGULATOR receiver
D3093_RS01655	COG3447	MASE1 domain protein
D3093_RS01655	COG5002	protein histidine kinase activity
D3093_RS01655	COG5001	Diguanylate cyclase
D3093_RS01690	COG1024	Enoyl-CoA hydratase
D3093_RS01700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3093_RS01705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D3093_RS01710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3093_RS01715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3093_RS01720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D3093_RS01720	COG2885	chlorophyll binding
D3093_RS01725	COG3243	poly(R)-hydroxyalkanoic acid synthase
D3093_RS01740	COG2814	Major facilitator Superfamily
D3093_RS01745	COG0436	Aminotransferase
D3093_RS01755	COG1494	fructose-1,6-bisphosphatase
D3093_RS01760	COG0371	Dehydrogenase
D3093_RS01790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3093_RS01790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3093_RS01800	COG0656	L-ascorbic acid biosynthetic process
D3093_RS01815	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3093_RS01825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3093_RS01830	COG0517	IMP dehydrogenase activity
D3093_RS01865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS01870	COG0045	succinate-CoA ligase (ADP-forming) activity
D3093_RS01895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D3093_RS01910	COG2084	Dehydrogenase
D3093_RS01915	COG3622	Belongs to the hyi family
D3093_RS01920	COG3960	tartronate-semialdehyde synthase activity
D3093_RS01925	COG0352	thiamine-phosphate diphosphorylase activity
D3093_RS01925	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D3093_RS01930	COG1802	Transcriptional regulator
D3093_RS01935	COG0469	pyruvate kinase activity
D3093_RS01945	COG0574	Belongs to the PEP-utilizing enzyme family
D3093_RS01945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3093_RS01975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS01985	COG0693	protein deglycase activity
D3093_RS01990	COG2197	response regulator
D3093_RS01995	COG2197	response regulator
D3093_RS02010	COG0829	nickel cation binding
D3093_RS02015	COG0831	urea catabolic process
D3093_RS02020	COG0832	Belongs to the urease beta subunit family
D3093_RS02025	COG0804	urea catabolic process
D3093_RS02030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3093_RS02035	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D3093_RS02040	COG0830	nickel cation binding
D3093_RS02045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D3093_RS02050	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D3093_RS02060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3093_RS02075	COG0640	Transcriptional regulator
D3093_RS02105	COG1396	sequence-specific DNA binding
D3093_RS02165	COG0463	Glycosyl transferase, family 2
D3093_RS02185	COG1940	carbohydrate kinase activity
D3093_RS02235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D3093_RS02235	COG2885	chlorophyll binding
D3093_RS02240	COG2197	response regulator
D3093_RS02245	COG2198	Histidine kinase
D3093_RS02245	COG2205	protein histidine kinase activity
D3093_RS02245	COG0784	Response regulator, receiver
D3093_RS02260	COG0564	pseudouridine synthase activity
D3093_RS02270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D3093_RS02270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D3093_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS02325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3093_RS02330	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3093_RS02340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3093_RS02345	COG0314	molybdopterin synthase activity
D3093_RS02355	COG1280	lysine exporter protein (LysE YggA)
D3093_RS02390	COG4957	zinc ion binding
D3093_RS02430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS02435	COG0174	glutamine synthetase
D3093_RS02445	COG3842	ATPase activity
D3093_RS02450	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS02455	COG1177	transmembrane transport
D3093_RS02460	COG2957	Belongs to the agmatine deiminase family
D3093_RS02485	COG0321	lipoyl(octanoyl) transferase activity
D3093_RS02485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3093_RS02490	COG0084	hydrolase, TatD family'
D3093_RS02495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3093_RS02500	COG0470	DNA polymerase III
D3093_RS02505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3093_RS02510	COG1686	Belongs to the peptidase S11 family
D3093_RS02525	COG0840	transmembrane signaling receptor activity
D3093_RS02530	COG0525	valine-tRNA ligase activity
D3093_RS02540	COG1538	Outer membrane efflux protein
D3093_RS02550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D3093_RS02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3093_RS02580	COG0494	nUDIX hydrolase
D3093_RS02595	COG2897	thiosulfate sulfurtransferase activity
D3093_RS02615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3093_RS02620	COG1126	abc transporter atp-binding protein
D3093_RS02625	COG0765	amino acid transport
D3093_RS02630	COG4597	amino acid ABC transporter
D3093_RS02635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS02640	COG0626	cystathionine gamma-synthase activity
D3093_RS02690	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3093_RS02720	COG2358	TRAP transporter, solute receptor (TAXI family
D3093_RS02755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3093_RS02755	COG3608	succinylglutamate desuccinylase aspartoacylase
D3093_RS02760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D3093_RS02765	COG0512	Glutamine amidotransferase of anthranilate synthase
D3093_RS02770	COG0737	Belongs to the 5'-nucleotidase family
D3093_RS02780	COG0686	Belongs to the AlaDH PNT family
D3093_RS02795	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3093_RS02815	COG1846	Transcriptional regulator
D3093_RS02820	COG1024	Enoyl-CoA hydratase
D3093_RS02825	COG1597	lipid kinase activity
D3093_RS02830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3093_RS02835	COG0113	porphobilinogen synthase activity
D3093_RS02840	COG1881	PFAM PEBP family protein
D3093_RS02850	COG2813	Specifically methylates the guanine in position
D3093_RS02855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D3093_RS02860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3093_RS02865	COG0741	lytic transglycosylase activity
D3093_RS02875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3093_RS02880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3093_RS02895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3093_RS02900	COG0360	Binds together with S18 to 16S ribosomal RNA
D3093_RS02905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3093_RS02915	COG0359	binds to the 23S rRNA
D3093_RS02925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D3093_RS02930	COG0305	Participates in initiation and elongation during chromosome replication
D3093_RS02935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3093_RS02940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D3093_RS02945	COG1127	ABC transporter
D3093_RS02960	COG0024	Methionine aminopeptidase
D3093_RS02975	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3093_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS02985	COG1160	GTP binding
D3093_RS03005	COG2197	response regulator
D3093_RS03015	COG2197	response regulator
D3093_RS03040	COG5002	protein histidine kinase activity
D3093_RS03040	COG2205	protein histidine kinase activity
D3093_RS03040	COG0784	Response regulator, receiver
D3093_RS03050	COG0840	transmembrane signaling receptor activity
D3093_RS03085	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D3093_RS03090	COG2814	Major facilitator Superfamily
D3093_RS03105	COG0789	Transcriptional regulator
D3093_RS03110	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS03130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D3093_RS03140	COG1116	anion transmembrane transporter activity
D3093_RS03140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS03155	COG0175	sulfate reduction
D3093_RS03160	COG0175	sulfate reduction
D3093_RS03165	COG1648	precorrin-2 dehydrogenase activity
D3093_RS03165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3093_RS03180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3093_RS03195	COG4651	solute:proton antiporter activity
D3093_RS03195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3093_RS03215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3093_RS03220	COG0416	fatty acid biosynthetic process
D3093_RS03225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3093_RS03245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D3093_RS03255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3093_RS03260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3093_RS03265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3093_RS03270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3093_RS03270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3093_RS03280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3093_RS03280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3093_RS03285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3093_RS03290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3093_RS03295	COG0698	ribose 5-phosphate isomerase
D3093_RS03315	COG3685	Protein conserved in bacteria
D3093_RS03335	COG2153	protein acetylation
D3093_RS03345	COG1793	dna ligase
D3093_RS03355	COG2313	pseudouridylate synthase activity
D3093_RS03365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3093_RS03385	COG1217	gtp-binding protein TYPA
D3093_RS03420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS03430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS03440	COG1755	Isoprenylcysteine carboxyl methyltransferase
D3093_RS03445	COG3424	synthase
D3093_RS03455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3093_RS03460	COG1492	cobalamin metabolic process
D3093_RS03520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3093_RS03535	COG1024	Enoyl-CoA hydratase
D3093_RS03545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3093_RS03550	COG3411	Ferredoxin
D3093_RS03570	COG3546	catalase activity
D3093_RS03575	COG2814	Major facilitator Superfamily
D3093_RS03580	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D3093_RS03625	COG0546	phosphoglycolate phosphatase activity
D3093_RS03635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3093_RS03665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS03675	COG0628	permease
D3093_RS03680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS03695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3093_RS03795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS03865	COG3108	Peptidase M15
D3093_RS03875	COG1773	rubredoxin
D3093_RS03890	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3093_RS03895	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
D3093_RS03915	COG2205	protein histidine kinase activity
D3093_RS03945	COG2824	Alkylphosphonate utilization operon protein PhnA
D3093_RS03960	COG0243	molybdopterin cofactor binding
D3093_RS03965	COG2070	2-Nitropropane dioxygenase
D3093_RS03970	COG3706	GGDEF domain
D3093_RS03985	COG1410	methionine synthase
D3093_RS03985	COG0646	methionine synthase
D3093_RS04005	COG2853	Lipoprotein
D3093_RS04020	COG0488	(ABC) transporter
D3093_RS04025	COG1671	Belongs to the UPF0178 family
D3093_RS04030	COG5002	protein histidine kinase activity
D3093_RS04030	COG2176	DNA-directed DNA polymerase activity
D3093_RS04055	COG1640	4-alpha-glucanotransferase
D3093_RS04060	COG0745	RESPONSE REGULATOR receiver
D3093_RS04080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D3093_RS04085	COG0366	Alpha amylase catalytic
D3093_RS04100	COG1218	3'(2'),5'-bisphosphate nucleotidase
D3093_RS04105	COG2833	Protein of unknown function (DUF455)
D3093_RS04120	COG1960	acyl-CoA dehydrogenase activity
D3093_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS04135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS04140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3093_RS04190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS04200	COG1846	Transcriptional regulator
D3093_RS04205	COG2267	carboxylic ester hydrolase activity
D3093_RS04220	COG2226	methyltransferase
D3093_RS04245	COG1201	RNA secondary structure unwinding
D3093_RS04255	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D3093_RS04260	COG0415	Belongs to the DNA photolyase family
D3093_RS04270	COG0735	belongs to the Fur family
D3093_RS04275	COG0523	cobalamin synthesis protein
D3093_RS04290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3093_RS04295	COG1234	tRNA 3'-trailer cleavage
D3093_RS04305	COG0840	transmembrane signaling receptor activity
D3093_RS04310	COG0840	transmembrane signaling receptor activity
D3093_RS04325	COG4520	surface antigen
D3093_RS04355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS04355	COG4191	Histidine kinase
D3093_RS04370	COG0784	Response regulator, receiver
D3093_RS04370	COG3437	response regulator, receiver
D3093_RS04390	COG2076	Multidrug Resistance protein
D3093_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS04400	COG1765	OsmC-like protein
D3093_RS04410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3093_RS04420	COG0697	spore germination
D3093_RS04425	COG0367	asparagine synthase
D3093_RS04440	COG0438	transferase activity, transferring glycosyl groups
D3093_RS04445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3093_RS04455	COG1086	Polysaccharide biosynthesis protein
D3093_RS04465	COG2885	chlorophyll binding
D3093_RS04480	COG0848	biopolymer transport protein
D3093_RS04490	COG0824	Thioesterase
D3093_RS04495	COG2255	four-way junction helicase activity
D3093_RS04510	COG0217	transcriptional regulatory protein
D3093_RS04515	COG1692	metallophosphoesterase
D3093_RS04520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3093_RS04565	COG1830	Aldolase
D3093_RS04570	COG0352	thiamine-phosphate diphosphorylase activity
D3093_RS04575	COG0730	response to heat
D3093_RS04580	COG2067	long-chain fatty acid transport protein
D3093_RS04585	COG0604	alcohol dehydrogenase
D3093_RS04590	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D3093_RS04595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3093_RS04600	COG0483	inositol monophosphate 1-phosphatase activity
D3093_RS04620	COG2826	transposase and inactivated derivatives, IS30 family
D3093_RS04625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3093_RS04630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3093_RS04635	COG0509	glycine decarboxylation via glycine cleavage system
D3093_RS04640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3093_RS04655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D3093_RS04665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3093_RS04670	COG0328	RNA-DNA hybrid ribonuclease activity
D3093_RS04675	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS04680	COG0678	peroxiredoxin activity
D3093_RS04685	COG4232	protein-disulfide reductase activity
D3093_RS04690	COG1678	Uncharacterized ACR, COG1678
D3093_RS04700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3093_RS04705	COG0612	Peptidase, M16
D3093_RS04715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D3093_RS04720	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D3093_RS04725	COG3346	SURF1 family
D3093_RS04740	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D3093_RS04745	COG0109	protoheme IX farnesyltransferase activity
D3093_RS04750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3093_RS04755	COG1565	acr, cog1565
D3093_RS04755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3093_RS04765	COG0312	modulator of DNA gyrase
D3093_RS04775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3093_RS04785	COG5487	UPF0391 membrane protein
D3093_RS04795	COG0741	lytic transglycosylase activity
D3093_RS04820	COG0564	pseudouridine synthase activity
D3093_RS04835	COG0515	serine threonine protein kinase
D3093_RS04835	COG3266	domain, Protein
D3093_RS04840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D3093_RS04845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D3093_RS04855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3093_RS04870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3093_RS04875	COG1295	ribonuclease BN
D3093_RS04880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3093_RS04890	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS04900	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3093_RS04910	COG0745	RESPONSE REGULATOR receiver
D3093_RS04920	COG0616	signal peptide processing
D3093_RS04935	COG0784	Response regulator, receiver
D3093_RS04935	COG5002	protein histidine kinase activity
D3093_RS04935	COG2198	Histidine kinase
D3093_RS04945	COG0390	transport system, permease component
D3093_RS04950	COG1116	anion transmembrane transporter activity
D3093_RS04960	COG0628	permease
D3093_RS04965	COG2205	protein histidine kinase activity
D3093_RS04985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3093_RS04990	COG0251	oxidation-reduction process
D3093_RS05000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3093_RS05000	COG0551	DNA topoisomerase type I activity
D3093_RS05030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3093_RS05040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3093_RS05065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3093_RS05080	COG0505	Belongs to the CarA family
D3093_RS05090	COG1403	HNH endonuclease
D3093_RS05105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3093_RS05110	COG1393	Belongs to the ArsC family
D3093_RS05115	COG2890	protein-(glutamine-N5) methyltransferase activity
D3093_RS05120	COG1214	PFAM Peptidase M22, glycoprotease
D3093_RS05120	COG0456	acetyltransferase
D3093_RS05160	COG0538	isocitrate dehydrogenase activity
D3093_RS05170	COG3932	Exopolysaccharide synthesis, ExoD
D3093_RS05190	COG0473	3-isopropylmalate dehydrogenase activity
D3093_RS05220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3093_RS05240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3093_RS05255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D3093_RS05275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3093_RS05280	COG1684	flagellar biosynthetic protein fliR
D3093_RS05285	COG1987	bacterial-type flagellum assembly
D3093_RS05290	COG1677	Flagellar hook-basal body complex protein FliE
D3093_RS05295	COG1558	bacterial-type flagellum-dependent cell motility
D3093_RS05300	COG1815	bacterial-type flagellum-dependent cell motility
D3093_RS05305	COG2257	FlhB HrpN YscU SpaS Family
D3093_RS05320	COG1338	Plays a role in the flagellum-specific transport system
D3093_RS05340	COG1360	Flagellar Motor Protein
D3093_RS05380	COG4786	Flagellar basal body rod
D3093_RS05385	COG4786	Flagellar basal body rod
D3093_RS05395	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D3093_RS05435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3093_RS05460	COG0500	methyltransferase
D3093_RS05465	COG1132	(ABC) transporter
D3093_RS05470	COG0254	rRNA binding
D3093_RS05480	COG0071	Belongs to the small heat shock protein (HSP20) family
D3093_RS05500	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D3093_RS05515	COG2186	Transcriptional regulator
D3093_RS05520	COG0563	adenylate kinase activity
D3093_RS05525	COG0201	protein transport
D3093_RS05530	COG0200	Binds to the 23S rRNA
D3093_RS05535	COG1841	ribosomal large subunit assembly
D3093_RS05550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3093_RS05555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3093_RS05560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3093_RS05570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D3093_RS05580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3093_RS05585	COG0255	Belongs to the universal ribosomal protein uL29 family
D3093_RS05590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3093_RS05595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D3093_RS05600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3093_RS05605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3093_RS05610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3093_RS05615	COG0089	rRNA binding
D3093_RS05620	COG0088	Forms part of the polypeptide exit tunnel
D3093_RS05630	COG0051	transcription antitermination factor activity, RNA binding
D3093_RS05645	COG0049	tRNA binding
D3093_RS05660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3093_RS05665	COG0085	RNA polymerase activity
D3093_RS05670	COG0222	ribosome binding
D3093_RS05675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3093_RS05680	COG0081	regulation of translation
D3093_RS05685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3093_RS05785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3093_RS05795	COG1940	carbohydrate kinase activity
D3093_RS05805	COG0840	transmembrane signaling receptor activity
D3093_RS05805	COG2972	Histidine kinase
D3093_RS05810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS05820	COG0411	ABC transporter
D3093_RS05850	COG0673	inositol 2-dehydrogenase activity
D3093_RS05860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D3093_RS05870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS05875	COG1309	transcriptional regulator
D3093_RS05885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3093_RS05905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3093_RS05950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3093_RS05955	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3093_RS05960	COG1530	ribonuclease E activity
D3093_RS05990	COG0436	Aminotransferase
D3093_RS06000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3093_RS06015	COG2264	protein methyltransferase activity
D3093_RS06025	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3093_RS06055	COG1597	lipid kinase activity
D3093_RS06065	COG0438	transferase activity, transferring glycosyl groups
D3093_RS06075	COG1519	Transferase
D3093_RS06080	COG1663	tetraacyldisaccharide 4'-kinase activity
D3093_RS06090	COG1280	lysine exporter protein (LysE YggA)
D3093_RS06120	COG3719	Belongs to the RNase T2 family
D3093_RS06125	COG0439	Biotin carboxylase
D3093_RS06130	COG0511	ligase activity, forming carbon-carbon bonds
D3093_RS06150	COG1230	cation diffusion facilitator family transporter
D3093_RS06165	COG0840	transmembrane signaling receptor activity
D3093_RS06180	COG3108	Peptidase M15
D3093_RS06185	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3093_RS06185	COG3409	Peptidoglycan-binding domain 1 protein
D3093_RS06215	COG2205	protein histidine kinase activity
D3093_RS06225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D3093_RS06255	COG1073	alpha beta
D3093_RS06260	COG1380	Effector of murein hydrolase LrgA
D3093_RS06265	COG1346	cytolysis
D3093_RS06270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3093_RS06275	COG0751	glycine-tRNA ligase activity
D3093_RS06305	COG0142	geranyltranstransferase activity
D3093_RS06330	COG4191	Histidine kinase
D3093_RS06330	COG0784	Response regulator, receiver
D3093_RS06345	COG2084	Dehydrogenase
D3093_RS06350	COG0277	FAD linked oxidase domain protein
D3093_RS06365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D3093_RS06370	COG0488	(ABC) transporter
D3093_RS06400	COG2001	Belongs to the MraZ family
D3093_RS06420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3093_RS06430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3093_RS06445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3093_RS06455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3093_RS06460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3093_RS06465	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3093_RS06470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3093_RS06475	COG0849	cell division
D3093_RS06480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3093_RS06495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3093_RS06520	COG0497	DNA recombination
D3093_RS06525	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3093_RS06540	COG0745	RESPONSE REGULATOR receiver
D3093_RS06545	COG0006	proline dipeptidase activity
D3093_RS06545	COG0006	proline dipeptidase activity
D3093_RS06555	COG2264	protein methyltransferase activity
D3093_RS06570	COG0210	DNA helicase
D3093_RS06575	COG2197	response regulator
D3093_RS06580	COG2197	response regulator
D3093_RS06610	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D3093_RS06620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3093_RS06630	COG2205	protein histidine kinase activity
D3093_RS06640	COG2205	protein histidine kinase activity
D3093_RS06640	COG2202	Pas domain
D3093_RS06680	COG2988	succinylglutamate desuccinylase activity
D3093_RS06685	COG3180	Ammonia monooxygenase
D3093_RS06695	COG0628	permease
D3093_RS06700	COG0330	HflC and HflK could
D3093_RS06720	COG0745	RESPONSE REGULATOR receiver
D3093_RS06740	COG1116	anion transmembrane transporter activity
D3093_RS06745	COG1643	Atp-dependent helicase
D3093_RS06760	COG2719	SpoVR family
D3093_RS06765	COG2718	Belongs to the UPF0229 family
D3093_RS06770	COG2766	serine protein kinase
D3093_RS06775	COG0745	RESPONSE REGULATOR receiver
D3093_RS06785	COG0784	Response regulator, receiver
D3093_RS06785	COG2205	protein histidine kinase activity
D3093_RS06790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3093_RS06805	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
D3093_RS06845	COG1116	anion transmembrane transporter activity
D3093_RS06895	COG1131	(ABC) transporter
D3093_RS06910	COG0723	plastoquinol--plastocyanin reductase activity
D3093_RS06925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3093_RS06935	COG0463	Glycosyl transferase, family 2
D3093_RS06965	COG0602	queuosine metabolic process
D3093_RS06970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3093_RS07010	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3093_RS07030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3093_RS07055	COG2010	Cytochrome c
D3093_RS07060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3093_RS07070	COG0799	negative regulation of ribosome biogenesis
D3093_RS07075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D3093_RS07080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3093_RS07090	COG0793	Belongs to the peptidase S41A family
D3093_RS07100	COG1051	belongs to the nudix hydrolase family
D3093_RS07120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D3093_RS07130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3093_RS07150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3093_RS07160	COG4974	Belongs to the 'phage' integrase family
D3093_RS07165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3093_RS07175	COG0596	Alpha beta hydrolase
D3093_RS07195	COG4191	Histidine kinase
D3093_RS07200	COG4106	trans-aconitate 2-methyltransferase activity
D3093_RS07220	COG2226	methyltransferase
D3093_RS07225	COG0126	phosphoglycerate kinase activity
D3093_RS07235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D3093_RS07250	COG3474	cytochrome
D3093_RS07255	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D3093_RS07285	COG4166	transmembrane transport
D3093_RS07290	COG4166	transmembrane transport
D3093_RS07295	COG4174	ABC transporter (Permease)
D3093_RS07300	COG4239	(ABC) transporter, permease
D3093_RS07315	COG4172	Belongs to the ABC transporter superfamily
D3093_RS07325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3093_RS07335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3093_RS07340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3093_RS07350	COG2358	TRAP transporter, solute receptor (TAXI family
D3093_RS07370	COG0587	DNA-directed DNA polymerase activity
D3093_RS07410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3093_RS07415	COG0625	glutathione transferase activity
D3093_RS07430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS07435	COG0601	transmembrane transport
D3093_RS07445	COG1024	Enoyl-CoA hydratase
D3093_RS07460	COG0583	DNA-binding transcription factor activity
D3093_RS07485	COG5001	Diguanylate cyclase
D3093_RS07490	COG0625	glutathione transferase activity
D3093_RS07495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3093_RS07505	COG0156	8-amino-7-oxononanoate synthase activity
D3093_RS07520	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS07535	COG1322	Protein conserved in bacteria
D3093_RS07540	COG1278	Cold shock
D3093_RS07550	COG0242	peptide deformylase activity
D3093_RS07555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3093_RS07560	COG0101	tRNA pseudouridine synthase activity
D3093_RS07580	COG2378	regulation of single-species biofilm formation
D3093_RS07585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3093_RS07600	COG0335	large ribosomal subunit rRNA binding
D3093_RS07610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3093_RS07615	COG0228	four-way junction DNA binding
D3093_RS07620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3093_RS07660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS07675	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D3093_RS07690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3093_RS07700	COG1131	(ABC) transporter
D3093_RS07710	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D3093_RS07715	COG0697	spore germination
D3093_RS07735	COG3206	protein involved in exopolysaccharide biosynthesis
D3093_RS07735	COG0489	protein tyrosine kinase activity
D3093_RS07745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D3093_RS07755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS07770	COG0438	transferase activity, transferring glycosyl groups
D3093_RS07800	COG1215	transferase activity, transferring glycosyl groups
D3093_RS07810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D3093_RS07820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D3093_RS07825	COG0706	membrane insertase activity
D3093_RS07830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D3093_RS07845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D3093_RS07855	COG0598	Magnesium transport protein CorA
D3093_RS07870	COG0825	malonyl-CoA metabolic process
D3093_RS07885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D3093_RS07890	COG4974	Belongs to the 'phage' integrase family
D3093_RS07910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3093_RS07915	COG0517	IMP dehydrogenase activity
D3093_RS07930	COG0271	Belongs to the BolA IbaG family
D3093_RS07960	COG1840	ABC-type Fe3 transport system, periplasmic component
D3093_RS07965	COG1741	Belongs to the pirin family
D3093_RS07970	COG1178	ABC-type Fe3 transport system permease component
D3093_RS07975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3093_RS07985	COG0135	phosphoribosylanthranilate isomerase activity
D3093_RS08005	COG2423	ornithine cyclodeaminase activity
D3093_RS08015	COG0776	regulation of translation
D3093_RS08025	COG0539	negative regulation of cytoplasmic translation
D3093_RS08040	COG0405	Gamma-glutamyltransferase
D3093_RS08060	COG1741	Belongs to the pirin family
D3093_RS08065	COG0303	'Molybdopterin
D3093_RS08080	COG2205	protein histidine kinase activity
D3093_RS08080	COG5002	protein histidine kinase activity
D3093_RS08080	COG0784	Response regulator, receiver
D3093_RS08090	COG0463	Glycosyl transferase, family 2
D3093_RS08100	COG0071	Belongs to the small heat shock protein (HSP20) family
D3093_RS08125	COG2755	lipolytic protein G-D-S-L family
D3093_RS08125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D3093_RS08130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3093_RS08160	COG1215	transferase activity, transferring glycosyl groups
D3093_RS08180	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS08215	COG3162	membrane
D3093_RS08230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3093_RS08235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3093_RS08240	COG1040	competence protein
D3093_RS08245	COG1987	bacterial-type flagellum assembly
D3093_RS08250	COG4106	trans-aconitate 2-methyltransferase activity
D3093_RS08270	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D3093_RS08275	COG0513	Belongs to the DEAD box helicase family
D3093_RS08280	COG1970	mechanosensitive ion channel activity
D3093_RS08285	COG0653	protein targeting
D3093_RS08290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3093_RS08295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D3093_RS08305	COG0494	nUDIX hydrolase
D3093_RS08310	COG0514	ATP-dependent DNA helicase (RecQ)
D3093_RS08335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS08335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS08345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS08375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3093_RS08390	COG0412	Dienelactone hydrolase
D3093_RS08395	COG0033	Phosphoglucomutase
D3093_RS08400	COG1278	Cold shock
D3093_RS08430	COG0302	gtp cyclohydrolase
D3093_RS08435	COG2202	Pas domain
D3093_RS08435	COG2205	protein histidine kinase activity
D3093_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS08465	COG0285	dihydrofolate synthase activity
D3093_RS08470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3093_RS08480	COG0133	tryptophan synthase activity
D3093_RS08485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS08490	COG2205	protein histidine kinase activity
D3093_RS08490	COG5002	protein histidine kinase activity
D3093_RS08490	COG0784	Response regulator, receiver
D3093_RS08495	COG2205	protein histidine kinase activity
D3093_RS08500	COG1252	NADH dehydrogenase
D3093_RS08535	COG0802	atpase or kinase
D3093_RS08545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3093_RS08550	COG2887	Belongs to the helicase family. UvrD subfamily
D3093_RS08555	COG1074	ATP-dependent DNA helicase activity
D3093_RS08565	COG0583	DNA-binding transcription factor activity
D3093_RS08575	COG3001	Fructosamine kinase
D3093_RS08580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3093_RS08585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D3093_RS08590	COG1573	uracil-dna glycosylase
D3093_RS08600	COG2154	pterin-4-alpha-carbinolamine dehydratase
D3093_RS08610	COG0598	Magnesium transport protein CorA
D3093_RS08615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3093_RS08620	COG1872	DUF167
D3093_RS08640	COG1715	Restriction endonuclease
D3093_RS08655	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D3093_RS08775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3093_RS08780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3093_RS08840	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3093_RS08845	COG4133	protoheme IX ABC transporter activity
D3093_RS08850	COG2985	domain, Protein
D3093_RS08885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3093_RS08895	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
D3093_RS08900	COG1138	Cytochrome C-type biogenesis protein
D3093_RS08905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3093_RS08910	COG3088	subunit of a heme lyase
D3093_RS08915	COG4235	cytochrome complex assembly
D3093_RS08920	COG0697	spore germination
D3093_RS08925	COG3339	Conserved Protein
D3093_RS08930	COG2897	thiosulfate sulfurtransferase activity
D3093_RS08945	COG0137	argininosuccinate synthase activity
D3093_RS08960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3093_RS08970	COG1595	DNA-templated transcription, initiation
D3093_RS08975	COG3806	Anti-sigma factor
D3093_RS09000	COG0004	ammonium transporteR
D3093_RS09005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D3093_RS09010	COG0297	glycogen (starch) synthase activity
D3093_RS09015	COG0481	GTPase activity
D3093_RS09025	COG0583	DNA-binding transcription factor activity
D3093_RS09035	COG0784	Response regulator, receiver
D3093_RS09035	COG3437	response regulator, receiver
D3093_RS09050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3093_RS09055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3093_RS09060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3093_RS09080	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
D3093_RS09100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D3093_RS09105	COG0583	DNA-binding transcription factor activity
D3093_RS09110	COG0477	Major facilitator Superfamily
D3093_RS09125	COG1253	flavin adenine dinucleotide binding
D3093_RS09130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3093_RS09150	COG2205	protein histidine kinase activity
D3093_RS09150	COG2202	Pas domain
D3093_RS09185	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3093_RS09190	COG1121	(ABC) transporter
D3093_RS09195	COG1321	iron dependent repressor
D3093_RS09195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3093_RS09200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3093_RS09210	COG1278	Cold shock
D3093_RS09215	COG2204	response regulator
D3093_RS09220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3093_RS09225	COG0756	dUTP diphosphatase activity
D3093_RS09235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3093_RS09245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3093_RS09260	COG0745	RESPONSE REGULATOR receiver
D3093_RS09270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3093_RS09280	COG0573	inorganic phosphate transmembrane transporter activity
D3093_RS09285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3093_RS09305	COG5002	protein histidine kinase activity
D3093_RS09310	COG0280	phosphate acetyltransferase
D3093_RS09310	COG0281	malic enzyme
D3093_RS09320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS09330	COG2217	Heavy metal translocating P-type atpase
D3093_RS09360	COG3278	Belongs to the heme-copper respiratory oxidase family
D3093_RS09380	COG2132	Multicopper oxidase
D3093_RS09395	COG1177	transmembrane transport
D3093_RS09400	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS09420	COG3842	ATPase activity
D3093_RS09425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D3093_RS09430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3093_RS09435	COG0268	Binds directly to 16S ribosomal RNA
D3093_RS09440	COG1024	Enoyl-CoA hydratase
D3093_RS09450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3093_RS09460	COG0859	PFAM glycosyl transferase family 9
D3093_RS09460	COG0457	Tetratricopeptide repeat
D3093_RS09465	COG2226	methyltransferase
D3093_RS09470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3093_RS09480	COG4166	transmembrane transport
D3093_RS09485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D3093_RS09490	COG0039	L-malate dehydrogenase activity
D3093_RS09520	COG1592	Rubrerythrin
D3093_RS09535	COG0584	glycerophosphoryl diester phosphodiesterase
D3093_RS09540	COG1509	lysine 2,3-aminomutase activity
D3093_RS09550	COG2321	neutral zinc metallopeptidase
D3093_RS09560	COG1185	polyribonucleotide nucleotidyltransferase activity
D3093_RS09570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3093_RS09595	COG0779	Required for maturation of 30S ribosomal subunits
D3093_RS09600	COG2329	Antibiotic biosynthesis monooxygenase
D3093_RS09605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3093_RS09610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3093_RS09615	COG1396	sequence-specific DNA binding
D3093_RS09620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D3093_RS09625	COG1253	flavin adenine dinucleotide binding
D3093_RS09635	COG1702	phosphate starvation-inducible protein PhoH
D3093_RS09640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3093_RS09670	COG1214	PFAM Peptidase M22, glycoprotease
D3093_RS09675	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D3093_RS09685	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3093_RS09710	COG0730	response to heat
D3093_RS09715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3093_RS09730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3093_RS09740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3093_RS09745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3093_RS09755	COG1121	(ABC) transporter
D3093_RS09760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3093_RS09780	COG0247	lactate metabolic process
D3093_RS09785	COG1139	Iron-sulfur cluster binding protein
D3093_RS09790	COG1556	Lactate utilization protein
D3093_RS09805	COG2205	protein histidine kinase activity
D3093_RS09810	COG0488	(ABC) transporter
D3093_RS09815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D3093_RS09870	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D3093_RS09875	COG4395	Tim44
D3093_RS09885	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D3093_RS09890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3093_RS09900	COG1981	membrane
D3093_RS09925	COG0237	dephospho-CoA kinase activity
D3093_RS09930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3093_RS09940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3093_RS09955	COG3411	Ferredoxin
D3093_RS09960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3093_RS09965	COG0445	tRNA wobble uridine modification
D3093_RS09970	COG0357	Ribosomal RNA small subunit methyltransferase G
D3093_RS10045	COG0745	RESPONSE REGULATOR receiver
D3093_RS10065	COG1234	tRNA 3'-trailer cleavage
D3093_RS10075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS10080	COG0601	transmembrane transport
D3093_RS10110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3093_RS10110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS10115	COG1132	(ABC) transporter
D3093_RS10135	COG0438	transferase activity, transferring glycosyl groups
D3093_RS10160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D3093_RS10165	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D3093_RS10170	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D3093_RS10185	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS10190	COG1309	transcriptional regulator
D3093_RS10195	COG0110	maltose O-acetyltransferase activity
D3093_RS10210	COG3012	SEC-C Motif Domain Protein
D3093_RS10220	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D3093_RS10225	COG0180	Tryptophanyl-tRNA synthetase
D3093_RS10235	COG2205	protein histidine kinase activity
D3093_RS10235	COG0784	Response regulator, receiver
D3093_RS10240	COG0683	leucine binding
D3093_RS10275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3093_RS10285	COG1366	Belongs to the anti-sigma-factor antagonist family
D3093_RS10305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3093_RS10310	COG0792	nuclease activity
D3093_RS10335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3093_RS10345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3093_RS10350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3093_RS10355	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D3093_RS10360	COG1420	regulation of RNA biosynthetic process
D3093_RS10390	COG0443	Heat shock 70 kDa protein
D3093_RS10395	COG0484	heat shock protein binding
D3093_RS10400	COG3706	GGDEF domain
D3093_RS10410	COG4181	ATPase activity
D3093_RS10425	COG0667	Aldo Keto reductase
D3093_RS10430	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3093_RS10435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3093_RS10440	COG0347	Belongs to the P(II) protein family
D3093_RS10445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3093_RS10470	COG0606	chelatase, subunit chli
D3093_RS10480	COG0747	negative chemotaxis
D3093_RS10490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS10495	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D3093_RS10515	COG3685	Protein conserved in bacteria
D3093_RS10535	COG1013	pyruvate-flavodoxin oxidoreductase activity
D3093_RS10540	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D3093_RS10540	COG0674	pyruvate-flavodoxin oxidoreductase activity
D3093_RS10545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3093_RS10550	COG2205	protein histidine kinase activity
D3093_RS10550	COG2202	Pas domain
D3093_RS10555	COG0693	protein deglycase activity
D3093_RS10560	COG2224	Isocitrate lyase
D3093_RS10565	COG3800	Transcriptional regulator
D3093_RS10565	COG1396	sequence-specific DNA binding
D3093_RS10580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3093_RS10585	COG0784	Response regulator, receiver
D3093_RS10585	COG3437	response regulator, receiver
D3093_RS10590	COG0668	transmembrane transport
D3093_RS10600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS10625	COG1612	heme a metabolic process
D3093_RS10630	COG0543	2 iron, 2 sulfur cluster binding
D3093_RS10630	COG0493	'glutamate synthase
D3093_RS10635	COG3772	lysozyme
D3093_RS10640	COG5425	PFAM Usg family protein
D3093_RS10645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3093_RS10650	COG0459	protein refolding
D3093_RS10655	COG0753	catalase activity
D3093_RS10660	COG1858	cytochrome C peroxidase
D3093_RS10665	COG3005	denitrification pathway
D3093_RS10685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3093_RS10695	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3093_RS10700	COG1842	Phage shock protein A
D3093_RS10715	COG3437	response regulator, receiver
D3093_RS10715	COG0784	Response regulator, receiver
D3093_RS10725	COG0671	phosphoesterase, PA-phosphatase related
D3093_RS10780	COG0747	negative chemotaxis
D3093_RS10785	COG0601	transmembrane transport
D3093_RS10790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS10795	COG0444	Belongs to the ABC transporter superfamily
D3093_RS10815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3093_RS10825	COG0302	gtp cyclohydrolase
D3093_RS10830	COG2967	ApaG domain
D3093_RS10860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS10875	COG5002	protein histidine kinase activity
D3093_RS10890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D3093_RS10895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS10895	COG4191	Histidine kinase
D3093_RS10905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3093_RS10915	COG2885	chlorophyll binding
D3093_RS10945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3093_RS10975	COG0181	hydroxymethylbilane synthase activity
D3093_RS10995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3093_RS11000	COG2350	Protein conserved in bacteria
D3093_RS11015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3093_RS11030	COG5508	conserved small protein
D3093_RS11035	COG0501	Belongs to the peptidase M48B family
D3093_RS11050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3093_RS11050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3093_RS11060	COG0138	bifunctional purine biosynthesis protein purh
D3093_RS11080	COG2264	protein methyltransferase activity
D3093_RS11085	COG2902	Dehydrogenase
D3093_RS11090	COG3437	response regulator, receiver
D3093_RS11090	COG2770	Histidine kinase
D3093_RS11100	COG0840	transmembrane signaling receptor activity
D3093_RS11110	COG0679	Auxin Efflux Carrier
D3093_RS11115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS11130	COG3118	belongs to the thioredoxin family
D3093_RS11135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3093_RS11140	COG2835	tetraacyldisaccharide 4'-kinase activity
D3093_RS11180	COG1285	pathogenesis
D3093_RS11185	COG2814	Major facilitator Superfamily
D3093_RS11195	COG0784	Response regulator, receiver
D3093_RS11195	COG2205	protein histidine kinase activity
D3093_RS11225	COG0395	ABC-type sugar transport system, permease component
D3093_RS11230	COG3842	ATPase activity
D3093_RS11235	COG0625	glutathione transferase activity
D3093_RS11250	COG0513	Belongs to the DEAD box helicase family
D3093_RS11270	COG5002	protein histidine kinase activity
D3093_RS11270	COG2205	protein histidine kinase activity
D3093_RS11270	COG0784	Response regulator, receiver
D3093_RS11275	COG4191	Histidine kinase
D3093_RS11280	COG1366	Belongs to the anti-sigma-factor antagonist family
D3093_RS11290	COG0745	RESPONSE REGULATOR receiver
D3093_RS11310	COG0745	RESPONSE REGULATOR receiver
D3093_RS11325	COG1366	Belongs to the anti-sigma-factor antagonist family
D3093_RS11330	COG0840	transmembrane signaling receptor activity
D3093_RS11335	COG2201	protein-glutamate methylesterase activity
D3093_RS11340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D3093_RS11350	COG0840	transmembrane signaling receptor activity
D3093_RS11355	COG0835	chemotaxis
D3093_RS11360	COG0643	Histidine kinase
D3093_RS11360	COG2198	Histidine kinase
D3093_RS11365	COG0745	RESPONSE REGULATOR receiver
D3093_RS11375	COG5002	protein histidine kinase activity
D3093_RS11385	COG2176	DNA-directed DNA polymerase activity
D3093_RS11385	COG5002	protein histidine kinase activity
D3093_RS11390	COG0745	RESPONSE REGULATOR receiver
D3093_RS11405	COG2917	probably involved in intracellular septation
D3093_RS11415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3093_RS11420	COG0552	protein localization to endoplasmic reticulum
D3093_RS11425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3093_RS11430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D3093_RS11480	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D3093_RS11495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D3093_RS11500	COG3706	GGDEF domain
D3093_RS11505	COG2205	protein histidine kinase activity
D3093_RS11510	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS11525	COG0045	succinate-CoA ligase (ADP-forming) activity
D3093_RS11530	COG0039	L-malate dehydrogenase activity
D3093_RS11545	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
D3093_RS11550	COG2076	Multidrug Resistance protein
D3093_RS11560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3093_RS11565	COG1199	ATP-dependent helicase activity
D3093_RS11565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3093_RS11580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D3093_RS11600	COG2084	Dehydrogenase
D3093_RS11610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3093_RS11645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3093_RS11845	COG0167	dihydroorotate dehydrogenase activity
D3093_RS11855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3093_RS11860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3093_RS11865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3093_RS11955	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS11995	COG1518	maintenance of DNA repeat elements
D3093_RS12000	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
D3093_RS12010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3093_RS12015	COG2304	oxidoreductase activity
D3093_RS12045	COG1136	(ABC) transporter
D3093_RS12100	COG0583	DNA-binding transcription factor activity
D3093_RS12105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS12110	COG1024	Enoyl-CoA hydratase
D3093_RS12125	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS12155	COG1902	pentaerythritol trinitrate reductase activity
D3093_RS12200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS12205	COG1116	anion transmembrane transporter activity
D3093_RS12210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS12215	COG0583	DNA-binding transcription factor activity
D3093_RS12265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3093_RS12270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3093_RS12280	COG0783	Belongs to the Dps family
D3093_RS12290	COG0492	ferredoxin-NADP+ reductase activity
D3093_RS12305	COG3660	Nucleoside-diphosphate-sugar epimerase
D3093_RS12310	COG1522	sequence-specific DNA binding
D3093_RS12320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3093_RS12325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3093_RS12350	COG1674	ftsk spoiiie
D3093_RS12360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3093_RS12370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3093_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS12380	COG1238	metal cluster binding
D3093_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS12435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS12435	COG2205	protein histidine kinase activity
D3093_RS12455	COG5002	protein histidine kinase activity
D3093_RS12465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3093_RS12475	COG3279	Response regulator of the LytR AlgR family
D3093_RS12490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3093_RS12500	COG1902	pentaerythritol trinitrate reductase activity
D3093_RS12520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D3093_RS12530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3093_RS12535	COG0047	phosphoribosylformylglycinamidine synthase activity
D3093_RS12540	COG0583	DNA-binding transcription factor activity
D3093_RS12550	COG2258	MOSC domain
D3093_RS12560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3093_RS12565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3093_RS12590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3093_RS12610	COG0024	Methionine aminopeptidase
D3093_RS12615	COG1489	DNA binding
D3093_RS12620	COG1546	Belongs to the CinA family
D3093_RS12620	COG1058	Belongs to the CinA family
D3093_RS12655	COG0124	histidyl-tRNA synthetase
D3093_RS12660	COG0418	dihydroorotase activity
D3093_RS12665	COG1570	exodeoxyribonuclease VII activity
D3093_RS12685	COG0590	tRNA wobble adenosine to inosine editing
D3093_RS12690	COG3360	Dodecin
D3093_RS12695	COG1187	pseudouridine synthase activity
D3093_RS12700	COG0742	ribosomal rna small subunit methyltransferase
D3093_RS12715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3093_RS12725	COG2084	Dehydrogenase
D3093_RS12735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS12740	COG3958	Transketolase
D3093_RS12745	COG3959	Transketolase, thiamine diphosphate binding domain
D3093_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS12755	COG0583	DNA-binding transcription factor activity
D3093_RS12760	COG1309	transcriptional regulator
D3093_RS12815	COG1749	Flagellar hook protein flgE
D3093_RS12820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3093_RS12830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS12840	COG0251	oxidation-reduction process
D3093_RS12850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS12860	COG0747	negative chemotaxis
D3093_RS12870	COG0583	DNA-binding transcription factor activity
D3093_RS12880	COG4221	oxidoreductase activity
D3093_RS12895	COG2201	protein-glutamate methylesterase activity
D3093_RS12905	COG0747	negative chemotaxis
D3093_RS12930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3093_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS12970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3093_RS12980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS12985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS13015	COG0667	Aldo Keto reductase
D3093_RS13020	COG5265	(ABC) transporter
D3093_RS13025	COG3284	Transcriptional regulator
D3093_RS13030	COG3199	ATP-NAD kinase
D3093_RS13035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3093_RS13040	COG0022	dehydrogenase e1 component
D3093_RS13045	COG0596	Alpha beta hydrolase
D3093_RS13045	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS13085	COG0644	oxidoreductase
D3093_RS13100	COG0745	RESPONSE REGULATOR receiver
D3093_RS13105	COG5002	protein histidine kinase activity
D3093_RS13105	COG0784	Response regulator, receiver
D3093_RS13110	COG2010	Cytochrome c
D3093_RS13125	COG1309	transcriptional regulator
D3093_RS13130	COG0604	alcohol dehydrogenase
D3093_RS13150	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS13155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3093_RS13175	COG0166	Belongs to the GPI family
D3093_RS13180	COG0612	Peptidase, M16
D3093_RS13185	COG0612	Peptidase, M16
D3093_RS13195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3093_RS13200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3093_RS13205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3093_RS13210	COG0196	riboflavin kinase activity
D3093_RS13215	COG2030	dehydratase
D3093_RS13225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3093_RS13250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3093_RS13255	COG2703	oxygen carrier activity
D3093_RS13280	COG0590	tRNA wobble adenosine to inosine editing
D3093_RS13290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS13305	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D3093_RS13330	COG1686	Belongs to the peptidase S11 family
D3093_RS13345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3093_RS13350	COG0746	molybdenum cofactor guanylyltransferase activity
D3093_RS13375	COG0243	molybdopterin cofactor binding
D3093_RS13375	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS13380	COG0437	4 iron, 4 sulfur cluster binding
D3093_RS13405	COG0235	Class ii aldolase
D3093_RS13415	COG3384	dioxygenase
D3093_RS13425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3093_RS13430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3093_RS13435	COG0356	it plays a direct role in the translocation of protons across the membrane
D3093_RS13445	COG1999	signal sequence binding
D3093_RS13460	COG1702	phosphate starvation-inducible protein PhoH
D3093_RS13470	COG2894	cell division
D3093_RS13475	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D3093_RS13495	COG0840	transmembrane signaling receptor activity
D3093_RS13500	COG4948	Mandelate Racemase Muconate Lactonizing
D3093_RS13505	COG1104	cysteine desulfurase activity
D3093_RS13515	COG2154	pterin-4-alpha-carbinolamine dehydratase
D3093_RS13530	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D3093_RS13555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3093_RS13560	COG1278	Cold shock
D3093_RS13570	COG2205	protein histidine kinase activity
D3093_RS13570	COG0784	Response regulator, receiver
D3093_RS13570	COG5002	protein histidine kinase activity
D3093_RS13595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3093_RS13650	COG5420	small protein containing a coiled-coil domain
D3093_RS13665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D3093_RS13670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D3093_RS13725	COG0121	glutamine amidotransferase
D3093_RS13740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3093_RS13765	COG5554	nitrogen fixation
D3093_RS13780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3093_RS13800	COG1309	transcriptional regulator
D3093_RS13810	COG1131	(ABC) transporter
D3093_RS13815	COG0842	Transport permease protein
D3093_RS13820	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
D3093_RS13830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3093_RS13840	COG0277	FAD linked oxidase domain protein
D3093_RS13845	COG0277	FAD linked oxidase domain protein
D3093_RS13850	COG0247	lactate metabolic process
D3093_RS13870	COG1960	acyl-CoA dehydrogenase activity
D3093_RS13885	COG0277	FAD linked oxidase domain protein
D3093_RS13890	COG0009	L-threonylcarbamoyladenylate synthase
D3093_RS13895	COG1192	Involved in chromosome partitioning
D3093_RS13905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3093_RS13910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D3093_RS13925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D3093_RS13930	COG2945	thiolester hydrolase activity
D3093_RS13935	COG1045	serine acetyltransferase
D3093_RS13950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D3093_RS13955	COG0633	Ferredoxin
D3093_RS13960	COG0482	sulfurtransferase activity
D3093_RS13980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS14005	COG4221	oxidoreductase activity
D3093_RS14020	COG2010	Cytochrome c
D3093_RS14020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3093_RS14025	COG2080	2 iron, 2 sulfur cluster binding
D3093_RS14035	COG5002	protein histidine kinase activity
D3093_RS14045	COG0745	RESPONSE REGULATOR receiver
D3093_RS14070	COG0432	Pfam Uncharacterised protein family UPF0047
D3093_RS14080	COG2951	lytic endotransglycosylase activity
D3093_RS14150	COG0114	fumarate hydratase activity
D3093_RS14215	COG2205	protein histidine kinase activity
D3093_RS14220	COG2927	DNA polymerase III (CHI subunit)
D3093_RS14225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3093_RS14255	COG0741	lytic transglycosylase activity
D3093_RS14280	COG1561	YicC-like family, N-terminal region
D3093_RS14285	COG0300	oxidoreductase activity
D3093_RS14290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3093_RS14295	COG3932	Exopolysaccharide synthesis, ExoD
D3093_RS14300	COG0488	(ABC) transporter
D3093_RS14305	COG0105	UTP biosynthetic process
D3093_RS14320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3093_RS14325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3093_RS14335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3093_RS14340	COG0628	permease
D3093_RS14350	COG0300	oxidoreductase activity
D3093_RS14355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3093_RS14370	COG3025	triphosphatase activity
D3093_RS14380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D3093_RS14385	COG0248	Ppx GppA phosphatase
D3093_RS14395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D3093_RS14400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3093_RS14425	COG5002	protein histidine kinase activity
D3093_RS14425	COG5001	Diguanylate cyclase
D3093_RS14425	COG3447	MASE1 domain protein
D3093_RS14430	COG2202	Pas domain
D3093_RS14430	COG2205	protein histidine kinase activity
D3093_RS14435	COG0784	Response regulator, receiver
D3093_RS14445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3093_RS14450	COG0793	Belongs to the peptidase S41A family
D3093_RS14455	COG0557	exoribonuclease II activity
D3093_RS14470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3093_RS14475	COG0758	DNA mediated transformation
D3093_RS14495	COG2814	Major facilitator Superfamily
D3093_RS14530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS14530	COG2205	protein histidine kinase activity
D3093_RS14535	COG0745	RESPONSE REGULATOR receiver
D3093_RS14570	COG0581	inorganic phosphate transmembrane transporter activity
D3093_RS14585	COG3842	ATPase activity
D3093_RS14595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3093_RS14600	COG1732	Glycine betaine
D3093_RS14605	COG1174	glycine betaine transport
D3093_RS14610	COG1125	glycine betaine transport
D3093_RS14615	COG1174	glycine betaine transport
D3093_RS14625	COG1652	LysM domain
D3093_RS14630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3093_RS14640	COG1024	Enoyl-CoA hydratase
D3093_RS14645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3093_RS14650	COG1609	Transcriptional regulator
D3093_RS14655	COG3265	gluconokinase activity
D3093_RS14665	COG3971	2-oxopent-4-enoate hydratase activity
D3093_RS14670	COG1609	Transcriptional regulator
D3093_RS14675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3093_RS14680	COG1126	abc transporter atp-binding protein
D3093_RS14690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS14695	COG0765	amino acid transport
D3093_RS14700	COG0765	amino acid transport
D3093_RS14705	COG0303	'Molybdopterin
D3093_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS14735	COG0730	response to heat
D3093_RS14750	COG0717	Belongs to the dCTP deaminase family
D3093_RS14760	COG0625	glutathione transferase activity
D3093_RS14765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3093_RS14785	COG2813	Specifically methylates the guanine in position
D3093_RS14785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3093_RS14790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3093_RS14800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3093_RS14805	COG0287	Prephenate dehydrogenase
D3093_RS14810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D3093_RS14820	COG0583	DNA-binding transcription factor activity
D3093_RS14830	COG3634	alkyl hydroperoxide reductase activity
D3093_RS14835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3093_RS14840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3093_RS14845	COG2080	2 iron, 2 sulfur cluster binding
D3093_RS14855	COG1988	membrane-bound metal-dependent
D3093_RS14875	COG0745	RESPONSE REGULATOR receiver
D3093_RS14885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3093_RS14890	COG0540	Belongs to the ATCase OTCase family
D3093_RS14905	COG0583	DNA-binding transcription factor activity
D3093_RS14920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D3093_RS14935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3093_RS14945	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3093_RS14950	COG0154	amidase activity
D3093_RS14955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D3093_RS14975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D3093_RS15105	COG4626	Terminase
D3093_RS15105	COG1802	Transcriptional regulator
D3093_RS15250	COG0714	Associated with various cellular activities
D3093_RS15270	COG0617	tRNA 3'-terminal CCA addition
D3093_RS15275	COG0408	coproporphyrinogen oxidase activity
D3093_RS15280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3093_RS15295	COG2857	Cytochrome c1
D3093_RS15295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3093_RS15315	COG0640	Transcriptional regulator
D3093_RS15325	COG0425	Belongs to the sulfur carrier protein TusA family
D3093_RS15345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3093_RS15355	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D3093_RS15390	COG4372	Transposase
D3093_RS15440	COG1136	(ABC) transporter
D3093_RS15440	COG0577	efflux transmembrane transporter activity
D3093_RS15445	COG1136	(ABC) transporter
D3093_RS15445	COG0577	efflux transmembrane transporter activity
D3093_RS15485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D3093_RS15490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS15500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D3093_RS15530	COG0667	Aldo Keto reductase
D3093_RS15535	COG0583	DNA-binding transcription factor activity
D3093_RS15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3093_RS15575	COG2703	oxygen carrier activity
D3093_RS15595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3093_RS15600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D3093_RS15605	COG1127	ABC transporter
D3093_RS15625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3093_RS15630	COG1271	oxidase subunit
D3093_RS15635	COG1294	oxidase, subunit
D3093_RS15650	COG0300	oxidoreductase activity
D3093_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS15690	COG2089	acid synthase
D3093_RS15695	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D3093_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS15725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3093_RS15730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3093_RS15745	COG0457	Tetratricopeptide repeat
D3093_RS15745	COG0859	PFAM glycosyl transferase family 9
D3093_RS15755	COG0457	Tetratricopeptide repeat
D3093_RS15755	COG0859	PFAM glycosyl transferase family 9
D3093_RS15805	COG0784	Response regulator, receiver
D3093_RS15840	COG1228	amidohydrolase
D3093_RS15855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D3093_RS15870	COG2226	methyltransferase
D3093_RS15880	COG0747	negative chemotaxis
D3093_RS15885	COG0601	transmembrane transport
D3093_RS15890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS15895	COG0444	Belongs to the ABC transporter superfamily
D3093_RS15900	COG4608	Belongs to the ABC transporter superfamily
D3093_RS15940	COG1666	GTP binding
D3093_RS15995	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3093_RS16000	COG1132	(ABC) transporter
D3093_RS16005	COG4191	Histidine kinase
D3093_RS16030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D3093_RS16040	COG2264	protein methyltransferase activity
D3093_RS16045	COG0583	DNA-binding transcription factor activity
D3093_RS16050	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3093_RS16055	COG0435	Glutathione S-transferase
D3093_RS16065	COG2197	response regulator
D3093_RS16075	COG0492	ferredoxin-NADP+ reductase activity
D3093_RS16095	COG0484	heat shock protein binding
D3093_RS16115	COG3038	cytochrome b561
D3093_RS16135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3093_RS16145	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3093_RS16155	COG1846	Transcriptional regulator
D3093_RS16165	COG3920	Histidine kinase
D3093_RS16180	COG1758	RNA polymerase activity
D3093_RS16195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D3093_RS16200	COG0736	holo-[acyl-carrier-protein] synthase activity
D3093_RS16205	COG0681	Belongs to the peptidase S26 family
D3093_RS16215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3093_RS16225	COG3768	UPF0283 membrane protein
D3093_RS16245	COG0740	serine-type endopeptidase activity
D3093_RS16250	COG1215	transferase activity, transferring glycosyl groups
D3093_RS16255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3093_RS16260	COG1566	PFAM secretion protein HlyD family protein
D3093_RS16265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS16275	COG2308	Evidence 4 Homologs of previously reported genes of
D3093_RS16275	COG2307	Protein conserved in bacteria
D3093_RS16295	COG2017	converts alpha-aldose to the beta-anomer
D3093_RS16335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D3093_RS16345	COG0513	Belongs to the DEAD box helicase family
D3093_RS16365	COG0187	DNA topoisomerase II activity
D3093_RS16370	COG1607	acyl-coa hydrolase
D3093_RS16375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D3093_RS16380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3093_RS16385	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS16385	COG0022	dehydrogenase e1 component
D3093_RS16390	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS16395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3093_RS16400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3093_RS16405	COG2867	negative regulation of translational initiation
D3093_RS16445	COG2204	response regulator
D3093_RS16450	COG0569	domain protein
D3093_RS16465	COG1923	regulation of RNA biosynthetic process
D3093_RS16470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3093_RS16485	COG0483	inositol monophosphate 1-phosphatase activity
D3093_RS16500	COG3956	TIGRFAM MazG family protein
D3093_RS16505	COG3260	NADH ubiquinone oxidoreductase 20
D3093_RS16510	COG0649	NAD binding
D3093_RS16515	COG0651	ATP synthesis coupled electron transport
D3093_RS16525	COG0650	Formate hydrogenlyase subunit 4
D3093_RS16530	COG0651	ATP synthesis coupled electron transport
D3093_RS16535	COG2183	response to ionizing radiation
D3093_RS16545	COG1280	lysine exporter protein (LysE YggA)
D3093_RS16575	COG0393	Putative heavy-metal-binding
D3093_RS16580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3093_RS16595	COG4166	transmembrane transport
D3093_RS16600	COG0625	glutathione transferase activity
D3093_RS16605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS16610	COG0366	Alpha amylase catalytic
D3093_RS16630	COG0840	transmembrane signaling receptor activity
D3093_RS16665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS16675	COG0583	DNA-binding transcription factor activity
D3093_RS16680	COG4336	lyase activity
D3093_RS16700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3093_RS16705	COG1984	allophanate hydrolase subunit 2
D3093_RS16710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D3093_RS16725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D3093_RS16730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3093_RS16735	COG0058	SHG alpha-glucan phosphorylase activity
D3093_RS16790	COG5002	protein histidine kinase activity
D3093_RS16795	COG0745	RESPONSE REGULATOR receiver
D3093_RS16830	COG1959	2 iron, 2 sulfur cluster binding
D3093_RS16835	COG0719	Fe-S assembly protein
D3093_RS16840	COG0396	ATPase activity
D3093_RS16845	COG0719	Fe-S assembly protein
D3093_RS16850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3093_RS16855	COG0822	iron-sulfur transferase activity
D3093_RS16865	COG0316	Belongs to the HesB IscA family
D3093_RS16875	COG0308	aminopeptidase N
D3093_RS16895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3093_RS16930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3093_RS16935	COG0697	spore germination
D3093_RS16945	COG2814	Major facilitator Superfamily
D3093_RS16950	COG0583	DNA-binding transcription factor activity
D3093_RS16965	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS16970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3093_RS16990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3093_RS16995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3093_RS17015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3093_RS17025	COG0129	dihydroxy-acid dehydratase activity
D3093_RS17135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3093_RS17140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3093_RS17145	COG0534	Mate efflux family protein
D3093_RS17185	COG0629	single-stranded DNA binding
D3093_RS17190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3093_RS17225	COG1562	ergosterol biosynthetic process
D3093_RS17230	COG1562	ergosterol biosynthetic process
D3093_RS17235	COG1233	COG1233 Phytoene dehydrogenase and related
D3093_RS17245	COG3737	Protein of unknown function (DUF498/DUF598)
D3093_RS17255	COG1862	Preprotein translocase
D3093_RS17275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D3093_RS17285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3093_RS17295	COG0805	protein transport
D3093_RS17300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3093_RS17305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3093_RS17310	COG3842	ATPase activity
D3093_RS17315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D3093_RS17320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D3093_RS17325	COG1994	Peptidase M50
D3093_RS17330	COG1472	Belongs to the glycosyl hydrolase 3 family
D3093_RS17345	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D3093_RS17350	COG0316	Belongs to the HesB IscA family
D3093_RS17355	COG0708	Exodeoxyribonuclease III
D3093_RS17375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3093_RS17380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3093_RS17395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3093_RS17415	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3093_RS17455	COG0582	viral genome integration into host DNA
D3093_RS17465	COG0066	3-isopropylmalate dehydratase activity
D3093_RS17470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3093_RS17475	COG1053	succinate dehydrogenase
D3093_RS17480	COG1335	isochorismatase
D3093_RS17525	COG0683	leucine binding
D3093_RS17530	COG2188	Transcriptional regulator
D3093_RS17580	COG2198	Histidine kinase
D3093_RS17580	COG0784	Response regulator, receiver
D3093_RS17580	COG5002	protein histidine kinase activity
D3093_RS17590	COG4548	von Willebrand factor, type A
D3093_RS17600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3093_RS17610	COG0444	Belongs to the ABC transporter superfamily
D3093_RS17615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS17620	COG0601	transmembrane transport
D3093_RS17695	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D3093_RS17855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3093_RS17860	COG3806	Anti-sigma factor
D3093_RS17865	COG1595	DNA-templated transcription, initiation
D3093_RS17875	COG1882	Formate acetyltransferase
D3093_RS17885	COG3008	intermembrane lipid transfer
D3093_RS17885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D3093_RS17890	COG2995	paraquat-inducible protein a
D3093_RS17900	COG0457	Tetratricopeptide repeat
D3093_RS17900	COG0859	PFAM glycosyl transferase family 9
D3093_RS17905	COG0281	malic enzyme
D3093_RS17905	COG0280	phosphate acetyltransferase
D3093_RS17910	COG1301	dicarboxylic acid transport
D3093_RS17915	COG4191	Histidine kinase
D3093_RS17920	COG2204	response regulator
D3093_RS17935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D3093_RS17935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D3093_RS17940	COG1268	BioY protein
D3093_RS17945	COG4770	biotin carboxylase activity
D3093_RS17950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3093_RS17960	COG1794	racemase activity, acting on amino acids and derivatives
D3093_RS17980	COG0519	Catalyzes the synthesis of GMP from XMP
D3093_RS17985	COG1247	-acetyltransferase
D3093_RS18010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D3093_RS18020	COG3813	Protein conserved in bacteria
D3093_RS18025	COG0357	Ribosomal RNA small subunit methyltransferase G
D3093_RS18025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3093_RS18060	COG4178	(ABC) transporter
D3093_RS18085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3093_RS18100	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
D3093_RS18105	COG0437	4 iron, 4 sulfur cluster binding
D3093_RS18110	COG5557	Pfam Polysulphide reductase, NrfD
D3093_RS18115	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
D3093_RS18120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3093_RS18125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D3093_RS18145	COG0298	carbon dioxide binding
D3093_RS18160	COG0375	protein maturation
D3093_RS18170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D3093_RS18180	COG0309	Hydrogenase expression formation protein (HypE)
D3093_RS18190	COG0793	Belongs to the peptidase S41A family
D3093_RS18195	COG1278	Cold shock
D3093_RS18200	COG3012	SEC-C Motif Domain Protein
D3093_RS18205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS18205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3093_RS18215	COG2189	Belongs to the N(4) N(6)-methyltransferase family
D3093_RS18235	COG1194	a g-specific adenine glycosylase
D3093_RS18250	COG1196	nuclear chromosome segregation
D3093_RS18265	COG3047	cAMP biosynthetic process
D3093_RS18280	COG1960	acyl-CoA dehydrogenase activity
D3093_RS18285	COG1024	Enoyl-CoA hydratase
D3093_RS18285	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3093_RS18290	COG0183	Belongs to the thiolase family
D3093_RS18305	COG2373	Large extracellular alpha-helical protein
D3093_RS18310	COG2202	Pas domain
D3093_RS18310	COG2205	protein histidine kinase activity
D3093_RS18315	COG0436	Aminotransferase
D3093_RS18330	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3093_RS18340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS18345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS18350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS18355	COG1737	Transcriptional regulator
D3093_RS18355	COG0837	glucose binding
D3093_RS18370	COG0386	Belongs to the glutathione peroxidase family
D3093_RS18385	COG3264	Mechanosensitive ion channel
D3093_RS18385	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D3093_RS18435	COG1063	alcohol dehydrogenase
D3093_RS18440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS18450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS18455	COG2721	sulfolactate sulfo-lyase activity
D3093_RS18460	COG0246	Mannitol dehydrogenase
D3093_RS18485	COG2358	TRAP transporter, solute receptor (TAXI family
D3093_RS18490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D3093_RS18495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D3093_RS18500	COG0583	DNA-binding transcription factor activity
D3093_RS18510	COG2391	methyltransferase activity
D3093_RS18525	COG3842	ATPase activity
D3093_RS18530	COG4149	molybdate abc transporter
D3093_RS18535	COG1840	ABC-type Fe3 transport system, periplasmic component
D3093_RS18550	COG1686	Belongs to the peptidase S11 family
D3093_RS18590	COG1396	sequence-specific DNA binding
D3093_RS18595	COG1766	The M ring may be actively involved in energy transduction
D3093_RS18605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3093_RS18610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3093_RS18615	COG2204	response regulator
D3093_RS18625	COG0552	protein localization to endoplasmic reticulum
D3093_RS18660	COG0745	RESPONSE REGULATOR receiver
D3093_RS18670	COG0583	DNA-binding transcription factor activity
D3093_RS18685	COG0784	Response regulator, receiver
D3093_RS18685	COG2198	Histidine kinase
D3093_RS18685	COG0643	Histidine kinase
D3093_RS18690	COG0835	chemotaxis
D3093_RS18695	COG2198	Histidine kinase
D3093_RS18695	COG0784	Response regulator, receiver
D3093_RS18695	COG0643	Histidine kinase
D3093_RS18720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3093_RS18725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3093_RS18730	COG1360	Flagellar Motor Protein
D3093_RS18735	COG2308	Evidence 4 Homologs of previously reported genes of
D3093_RS18755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS18755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS18760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS18765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3093_RS18770	COG1381	Involved in DNA repair and RecF pathway recombination
D3093_RS18780	COG5001	Diguanylate cyclase
D3093_RS18820	COG2884	Cell division ATP-binding protein ftsE
D3093_RS18850	COG0586	Pfam SNARE associated Golgi protein
D3093_RS18855	COG0505	Belongs to the CarA family
D3093_RS18865	COG3135	benzoate transporter
D3093_RS18870	COG0583	DNA-binding transcription factor activity
D3093_RS18875	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3093_RS18890	COG0488	(ABC) transporter
D3093_RS18900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS18920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3093_RS18930	COG0612	Peptidase, M16
D3093_RS18975	COG2223	nitrite transmembrane transporter activity
D3093_RS18980	COG0716	FMN binding
D3093_RS18995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS19005	COG1392	Phosphate transport regulator
D3093_RS19010	COG0306	phosphate transporter
D3093_RS19045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS19055	COG4191	Histidine kinase
D3093_RS19055	COG0784	Response regulator, receiver
D3093_RS19070	COG1283	sodium-dependent phosphate transmembrane transporter activity
D3093_RS19080	COG0583	DNA-binding transcription factor activity
D3093_RS19095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3093_RS19105	COG0288	reversible hydration of carbon dioxide
D3093_RS19120	COG4948	Mandelate Racemase Muconate Lactonizing
D3093_RS19125	COG0583	DNA-binding transcription factor activity
D3093_RS19130	COG0625	glutathione transferase activity
D3093_RS19180	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D3093_RS19190	COG1335	isochorismatase
D3093_RS19195	COG4191	Histidine kinase
D3093_RS19200	COG4566	intracellular signal transduction
D3093_RS19250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3093_RS19260	COG1396	sequence-specific DNA binding
D3093_RS19270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS19285	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS19300	COG3920	Histidine kinase
D3093_RS19335	COG4651	solute:proton antiporter activity
D3093_RS19335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3093_RS19345	COG3243	poly(R)-hydroxyalkanoic acid synthase
D3093_RS19350	COG3932	Exopolysaccharide synthesis, ExoD
D3093_RS19425	COG2205	protein histidine kinase activity
D3093_RS19425	COG2198	Histidine kinase
D3093_RS19425	COG0784	Response regulator, receiver
D3093_RS19430	COG0784	Response regulator, receiver
D3093_RS19430	COG2205	protein histidine kinase activity
D3093_RS19430	COG5002	protein histidine kinase activity
D3093_RS19435	COG2204	response regulator
D3093_RS19440	COG0745	RESPONSE REGULATOR receiver
D3093_RS19455	COG2244	polysaccharide biosynthetic process
D3093_RS19470	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3093_RS19490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3093_RS19515	COG1216	Glycosyl transferase, family 2
D3093_RS19595	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
D3093_RS19600	COG1082	Xylose isomerase domain protein TIM barrel
D3093_RS19625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS19630	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS19640	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS19645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3093_RS19715	COG3328	transposase activity
D3093_RS19820	COG1881	PFAM PEBP family protein
D3093_RS19840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS19860	COG0484	heat shock protein binding
D3093_RS19885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3093_RS19885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D3093_RS19905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3093_RS19925	COG0071	Belongs to the small heat shock protein (HSP20) family
D3093_RS19940	COG0542	response to heat
D3093_RS19950	COG0459	protein refolding
D3093_RS19955	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3093_RS19960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3093_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS20005	COG0583	DNA-binding transcription factor activity
D3093_RS20055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS20060	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
D3093_RS20065	COG1301	dicarboxylic acid transport
D3093_RS20070	COG2828	Protein conserved in bacteria
D3093_RS20075	COG0583	DNA-binding transcription factor activity
D3093_RS20080	COG0583	DNA-binding transcription factor activity
D3093_RS20130	COG0739	heme binding
D3093_RS20145	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
D3093_RS20160	COG0745	RESPONSE REGULATOR receiver
D3093_RS20165	COG0642	Histidine kinase
D3093_RS20175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D3093_RS20180	COG1660	Displays ATPase and GTPase activities
D3093_RS20185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3093_RS20185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3093_RS20190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3093_RS20210	COG4206	TonB-dependent receptor
D3093_RS20220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS20295	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS20300	COG1116	anion transmembrane transporter activity
D3093_RS20300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS20325	COG0784	Response regulator, receiver
D3093_RS20325	COG5002	protein histidine kinase activity
D3093_RS20325	COG2205	protein histidine kinase activity
D3093_RS20340	COG1695	Transcriptional regulator
D3093_RS20345	COG4607	ABC-type enterochelin transport system periplasmic component
D3093_RS20350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS20355	COG4605	iron ion homeostasis
D3093_RS20360	COG4604	ABC transporter, ATP-binding protein
D3093_RS20375	COG3128	pkhd-type hydroxylase
D3093_RS20380	COG4774	siderophore transport
D3093_RS20400	COG0671	phosphoesterase, PA-phosphatase related
D3093_RS20405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D3093_RS20420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3093_RS20425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3093_RS20430	COG0842	Transport permease protein
D3093_RS20435	COG2137	regulation of response to DNA damage stimulus
D3093_RS20445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D3093_RS20455	COG1703	isobutyryl-CoA mutase activity
D3093_RS20465	COG5265	(ABC) transporter
D3093_RS20470	COG0840	transmembrane signaling receptor activity
D3093_RS20485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3093_RS20490	COG1272	protein, Hemolysin III
D3093_RS20495	COG0542	response to heat
D3093_RS20515	COG2890	protein-(glutamine-N5) methyltransferase activity
D3093_RS20525	COG2852	Protein conserved in bacteria
D3093_RS20535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3093_RS20540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D3093_RS20555	COG2070	2-Nitropropane dioxygenase
D3093_RS20560	COG0527	aspartate kinase activity
D3093_RS20565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3093_RS20570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3093_RS20575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3093_RS20580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3093_RS20585	COG1137	ATPase activity
D3093_RS20620	COG2223	nitrite transmembrane transporter activity
D3093_RS20640	COG1214	PFAM Peptidase M22, glycoprotease
D3093_RS20640	COG0456	acetyltransferase
D3093_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS20695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS20720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS20725	COG2864	formate dehydrogenase
D3093_RS20730	COG0437	4 iron, 4 sulfur cluster binding
D3093_RS20735	COG0243	molybdopterin cofactor binding
D3093_RS20735	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS20775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3093_RS20795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS20805	COG3648	Uricase
D3093_RS20805	COG3195	allantoin biosynthetic process
D3093_RS20820	COG0583	DNA-binding transcription factor activity
D3093_RS20825	COG1609	Transcriptional regulator
D3093_RS20875	COG1032	radical SAM domain protein
D3093_RS20885	COG0791	NLP P60 protein
D3093_RS20890	COG1648	precorrin-2 dehydrogenase activity
D3093_RS20890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3093_RS20895	COG0243	molybdopterin cofactor binding
D3093_RS20900	COG2146	nitrite reductase [NAD(P)H] activity
D3093_RS20905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3093_RS20910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS20920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS20920	COG1116	anion transmembrane transporter activity
D3093_RS20925	COG3707	response regulator
D3093_RS20940	COG0251	oxidation-reduction process
D3093_RS20945	COG0583	DNA-binding transcription factor activity
D3093_RS20960	COG1475	DNA binding
D3093_RS20965	COG1192	Involved in chromosome partitioning
D3093_RS20980	COG0420	3'-5' exonuclease activity
D3093_RS21020	COG1942	4-Oxalocrotonate Tautomerase
D3093_RS21025	COG0235	Class ii aldolase
D3093_RS21045	COG0243	molybdopterin cofactor binding
D3093_RS21045	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS21050	COG0437	4 iron, 4 sulfur cluster binding
D3093_RS21055	COG2864	formate dehydrogenase
D3093_RS21060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3093_RS21070	COG2205	protein histidine kinase activity
D3093_RS21075	COG0745	RESPONSE REGULATOR receiver
D3093_RS21090	COG0840	transmembrane signaling receptor activity
D3093_RS21100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3093_RS21110	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D3093_RS21140	COG2027	D-alanyl-D-alanine carboxypeptidase
D3093_RS21150	COG2091	lysine biosynthetic process via aminoadipic acid
D3093_RS21155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3093_RS21160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3093_RS21170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3093_RS21170	COG2111	Na H antiporter
D3093_RS21175	COG1006	Multisubunit Na H antiporter MnhC subunit
D3093_RS21180	COG0651	ATP synthesis coupled electron transport
D3093_RS21185	COG1863	multisubunit Na H antiporter MnhE subunit
D3093_RS21190	COG2212	antiporter activity
D3093_RS21195	COG1320	monovalent cation:proton antiporter activity
D3093_RS21235	COG4615	Cyclic peptide transporter
D3093_RS21270	COG0683	leucine binding
D3093_RS21295	COG3842	ATPase activity
D3093_RS21305	COG1175	transmembrane transport
D3093_RS21325	COG1024	Enoyl-CoA hydratase
D3093_RS21340	COG4221	oxidoreductase activity
D3093_RS21345	COG1609	Transcriptional regulator
D3093_RS21375	COG1966	Carbon starvation protein
D3093_RS21380	COG2879	small protein
D3093_RS21395	COG4221	oxidoreductase activity
D3093_RS21415	COG0765	amino acid transport
D3093_RS21420	COG0765	amino acid transport
D3093_RS21455	COG0840	transmembrane signaling receptor activity
D3093_RS21460	COG2423	ornithine cyclodeaminase activity
D3093_RS21465	COG0657	acetylesterase activity
D3093_RS21495	COG2814	Major facilitator Superfamily
D3093_RS21500	COG0583	DNA-binding transcription factor activity
D3093_RS21505	COG0747	negative chemotaxis
D3093_RS21510	COG0601	transmembrane transport
D3093_RS21550	COG4520	surface antigen
D3093_RS21595	COG2900	Belongs to the SlyX family
D3093_RS21615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3093_RS21620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3093_RS21625	COG2080	2 iron, 2 sulfur cluster binding
D3093_RS21630	COG0583	DNA-binding transcription factor activity
D3093_RS21645	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
D3093_RS21650	COG2301	Belongs to the HpcH HpaI aldolase family
D3093_RS21655	COG1960	acyl-CoA dehydrogenase activity
D3093_RS21695	COG0438	transferase activity, transferring glycosyl groups
D3093_RS21730	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3093_RS21735	COG0741	lytic transglycosylase activity
D3093_RS21740	COG1573	uracil-dna glycosylase
D3093_RS21765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS21790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3093_RS21795	COG1959	2 iron, 2 sulfur cluster binding
D3093_RS21810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D3093_RS21820	COG4208	sulfate ABC transporter
D3093_RS21845	COG0745	RESPONSE REGULATOR receiver
D3093_RS21870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3093_RS21875	COG0367	asparagine synthase
D3093_RS21880	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS21900	COG0438	transferase activity, transferring glycosyl groups
D3093_RS21910	COG1215	transferase activity, transferring glycosyl groups
D3093_RS21930	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D3093_RS21940	COG3693	PFAM glycoside hydrolase, family 10
D3093_RS21950	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3093_RS21960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3093_RS21965	COG0588	phosphoglycerate mutase activity
D3093_RS21990	COG5002	protein histidine kinase activity
D3093_RS22000	COG4520	surface antigen
D3093_RS22015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3093_RS22025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3093_RS22040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3093_RS22050	COG1530	ribonuclease E activity
D3093_RS22055	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D3093_RS22085	COG1192	Involved in chromosome partitioning
D3093_RS22090	COG1522	sequence-specific DNA binding
D3093_RS22100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3093_RS22120	COG1309	transcriptional regulator
D3093_RS22135	COG5507	3-demethylubiquinone-9 3-methyltransferase
D3093_RS22145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3093_RS22155	COG1917	Cupin 2, conserved barrel domain protein
D3093_RS22155	COG1396	sequence-specific DNA binding
D3093_RS22165	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS22170	COG2182	Extracellular solute-binding protein
D3093_RS22175	COG3842	ATPase activity
D3093_RS22180	COG0583	DNA-binding transcription factor activity
D3093_RS22190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS22220	COG0471	metal ion transport
D3093_RS22220	COG3273	potassium ion transport
D3093_RS22230	COG2814	Major facilitator Superfamily
D3093_RS22235	COG0583	DNA-binding transcription factor activity
D3093_RS22245	COG1566	PFAM secretion protein HlyD family protein
D3093_RS22290	COG4520	surface antigen
D3093_RS22295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3093_RS22310	COG0789	Transcriptional regulator
D3093_RS22315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3093_RS22325	COG2860	membrane
D3093_RS22330	COG1741	Belongs to the pirin family
D3093_RS22355	COG2217	Heavy metal translocating P-type atpase
D3093_RS22390	COG1657	PFAM Prenyltransferase squalene oxidase
D3093_RS22410	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D3093_RS22425	COG2205	protein histidine kinase activity
D3093_RS22435	COG1253	flavin adenine dinucleotide binding
D3093_RS22440	COG0772	Belongs to the SEDS family
D3093_RS22460	COG0019	diaminopimelate decarboxylase activity
D3093_RS22475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3093_RS22485	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3093_RS22495	COG2086	electron transfer activity
D3093_RS22510	COG2723	6-phospho-beta-galactosidase activity
D3093_RS22570	COG1137	ATPase activity
D3093_RS22575	COG0840	transmembrane signaling receptor activity
D3093_RS22580	COG0795	lipopolysaccharide-transporting ATPase activity
D3093_RS22605	COG1749	Flagellar hook protein flgE
D3093_RS22605	COG1749	Flagellar hook protein flgE
D3093_RS22630	COG0737	Belongs to the 5'-nucleotidase family
D3093_RS22635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3093_RS22640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3093_RS22645	COG1309	transcriptional regulator
D3093_RS22650	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS22655	COG0778	Nitroreductase
D3093_RS22660	COG1797	cobyrinic acid a,c-diamide synthase activity
D3093_RS22690	COG2099	Precorrin-6x reductase
D3093_RS22740	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3093_RS22750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3093_RS22755	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS22760	COG0625	glutathione transferase activity
D3093_RS22785	COG1640	4-alpha-glucanotransferase
D3093_RS22805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS22820	COG0745	RESPONSE REGULATOR receiver
D3093_RS22825	COG2205	protein histidine kinase activity
D3093_RS22825	COG2198	Histidine kinase
D3093_RS22825	COG0784	Response regulator, receiver
D3093_RS22830	COG1278	Cold shock
D3093_RS22840	COG1846	Transcriptional regulator
D3093_RS22845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3093_RS22850	COG0556	nucleotide-excision repair
D3093_RS22935	COG0438	transferase activity, transferring glycosyl groups
D3093_RS22950	COG0583	DNA-binding transcription factor activity
D3093_RS22955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS22970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS22975	COG4172	Belongs to the ABC transporter superfamily
D3093_RS22995	COG0028	Belongs to the TPP enzyme family
D3093_RS23000	COG3246	L-lysine catabolic process to acetate
D3093_RS23015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS23020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS23030	COG1850	ribulose-bisphosphate carboxylase activity
D3093_RS23040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS23045	COG2204	response regulator
D3093_RS23070	COG0670	Belongs to the BI1 family
D3093_RS23090	COG4459	periplasmic nitrate reductase
D3093_RS23095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3093_RS23115	COG3005	denitrification pathway
D3093_RS23145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3093_RS23150	COG1845	cytochrome c oxidase, subunit III
D3093_RS23155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3093_RS23160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3093_RS23165	COG0477	Major facilitator Superfamily
D3093_RS23180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3093_RS23210	COG0392	lysyltransferase activity
D3093_RS23215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3093_RS23245	COG0583	DNA-binding transcription factor activity
D3093_RS23250	COG0375	protein maturation
D3093_RS23255	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS23260	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3093_RS23265	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3093_RS23270	COG0651	ATP synthesis coupled electron transport
D3093_RS23275	COG0650	Formate hydrogenlyase subunit 4
D3093_RS23280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3093_RS23285	COG4237	Hydrogenase 4 membrane
D3093_RS23290	COG0651	ATP synthesis coupled electron transport
D3093_RS23295	COG3261	NADH dehydrogenase
D3093_RS23295	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
D3093_RS23300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3093_RS23305	COG3260	NADH ubiquinone oxidoreductase 20
D3093_RS23315	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3093_RS23320	COG2116	formate transmembrane transporter activity
D3093_RS23325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3093_RS23330	COG0375	protein maturation
D3093_RS23365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3093_RS23385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
D3093_RS23390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS23410	COG1846	Transcriptional regulator
D3093_RS23415	COG1764	response to oxidative stress
D3093_RS23440	COG2113	Glycine betaine
D3093_RS23445	COG4176	ABC-type proline glycine betaine transport system permease component
D3093_RS23450	COG4175	Glycine betaine
D3093_RS23455	COG0339	signal peptide processing
D3093_RS23485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS23490	COG0765	amino acid transport
D3093_RS23540	COG0840	transmembrane signaling receptor activity
D3093_RS23545	COG4178	(ABC) transporter
D3093_RS23555	COG1475	DNA binding
D3093_RS23560	COG1192	Involved in chromosome partitioning
D3093_RS23565	COG4783	chaperone-mediated protein folding
D3093_RS23585	COG3622	Belongs to the hyi family
D3093_RS23595	COG1215	transferase activity, transferring glycosyl groups
D3093_RS23610	COG3307	-O-antigen
D3093_RS23615	COG0489	protein tyrosine kinase activity
D3093_RS23615	COG3206	protein involved in exopolysaccharide biosynthesis
D3093_RS23645	COG1216	Glycosyl transferase, family 2
D3093_RS23715	COG0640	Transcriptional regulator
D3093_RS23720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3093_RS23745	COG4566	intracellular signal transduction
D3093_RS23760	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS23770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3093_RS23780	COG1994	Peptidase M50
D3093_RS23780	COG0517	IMP dehydrogenase activity
D3093_RS23795	COG1522	sequence-specific DNA binding
D3093_RS23800	COG0583	DNA-binding transcription factor activity
D3093_RS23805	COG2271	Major facilitator Superfamily
D3093_RS23810	COG1802	Transcriptional regulator
D3093_RS23815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS23825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS23825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS23830	COG2354	Protein conserved in bacteria
D3093_RS23850	COG1418	mRNA catabolic process
D3093_RS23855	COG1131	(ABC) transporter
D3093_RS23860	COG0842	Transport permease protein
D3093_RS23865	COG3791	Glutathione-dependent formaldehyde-activating
D3093_RS23870	COG0154	amidase activity
D3093_RS23875	COG0154	amidase activity
D3093_RS23880	COG1335	isochorismatase
D3093_RS23885	COG0747	negative chemotaxis
D3093_RS23890	COG0601	transmembrane transport
D3093_RS23895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS23905	COG4608	Belongs to the ABC transporter superfamily
D3093_RS23910	COG1335	isochorismatase
D3093_RS23915	COG3180	Ammonia monooxygenase
D3093_RS23920	COG1802	Transcriptional regulator
D3093_RS23930	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D3093_RS23935	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D3093_RS23940	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D3093_RS23945	COG2205	protein histidine kinase activity
D3093_RS23955	COG0861	Integral membrane protein TerC family
D3093_RS23965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS23970	COG2353	YceI-like domain
D3093_RS23990	COG4566	intracellular signal transduction
D3093_RS23995	COG4566	intracellular signal transduction
D3093_RS24000	COG4191	Histidine kinase
D3093_RS24020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS24035	COG0427	acetyl-CoA hydrolase
D3093_RS24050	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS24055	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS24060	COG3842	ATPase activity
D3093_RS24070	COG1024	Enoyl-CoA hydratase
D3093_RS24180	COG0583	DNA-binding transcription factor activity
D3093_RS24190	COG3800	Transcriptional regulator
D3093_RS24190	COG1396	sequence-specific DNA binding
D3093_RS24200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3093_RS24220	COG2828	Protein conserved in bacteria
D3093_RS24240	COG2223	nitrite transmembrane transporter activity
D3093_RS24290	COG0489	protein tyrosine kinase activity
D3093_RS24300	COG4964	Belongs to the GSP D family
D3093_RS24330	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS24340	COG2205	protein histidine kinase activity
D3093_RS24340	COG0784	Response regulator, receiver
D3093_RS24345	COG3609	addiction module antidote protein, CC2985 family
D3093_RS24350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3093_RS24355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3093_RS24370	COG4191	Histidine kinase
D3093_RS24370	COG0784	Response regulator, receiver
D3093_RS24375	COG1454	alcohol dehydrogenase
D3093_RS24380	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS24415	COG0583	DNA-binding transcription factor activity
D3093_RS24440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3093_RS24445	COG1414	Transcriptional regulator
D3093_RS24450	COG2376	Dihydroxyacetone kinase
D3093_RS24465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS24475	COG2610	gluconate transmembrane transporter activity
D3093_RS24495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3093_RS24500	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS24505	COG3842	ATPase activity
D3093_RS24515	COG0277	FAD linked oxidase domain protein
D3093_RS24530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3093_RS24535	COG0459	protein refolding
D3093_RS24545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3093_RS24550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS24555	COG1396	sequence-specific DNA binding
D3093_RS24560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3093_RS24565	COG0022	dehydrogenase e1 component
D3093_RS24570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS24580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS24580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS24585	COG2175	clavaminate synthase activity
D3093_RS24595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS24600	COG1116	anion transmembrane transporter activity
D3093_RS24605	COG2175	clavaminate synthase activity
D3093_RS24625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS24630	COG3181	Tripartite tricarboxylate transporter family receptor
D3093_RS24640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS24645	COG4948	Mandelate Racemase Muconate Lactonizing
D3093_RS24655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS24660	COG0444	Belongs to the ABC transporter superfamily
D3093_RS24665	COG4608	Belongs to the ABC transporter superfamily
D3093_RS24675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3093_RS24680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS24685	COG0747	negative chemotaxis
D3093_RS24695	COG0601	transmembrane transport
D3093_RS24700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS24705	COG0444	Belongs to the ABC transporter superfamily
D3093_RS24710	COG4608	Belongs to the ABC transporter superfamily
D3093_RS24715	COG0697	spore germination
D3093_RS24720	COG1982	Orn Lys Arg decarboxylase major
D3093_RS24730	COG1335	isochorismatase
D3093_RS24740	COG1917	Cupin 2, conserved barrel domain protein
D3093_RS24740	COG1396	sequence-specific DNA binding
D3093_RS24745	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS24765	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS24770	COG1024	Enoyl-CoA hydratase
D3093_RS24775	COG2186	Transcriptional regulator
D3093_RS24785	COG2382	esterase
D3093_RS24790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3093_RS24800	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS24805	COG3433	isochorismatase activity
D3093_RS24805	COG1535	isochorismatase
D3093_RS24810	COG1021	2,3-dihydroxybenzoate-AMP ligase
D3093_RS24815	COG1169	isochorismate synthase
D3093_RS24835	COG4771	TonB-dependent receptor
D3093_RS24890	COG1253	flavin adenine dinucleotide binding
D3093_RS24920	COG0586	Pfam SNARE associated Golgi protein
D3093_RS24940	COG1802	Transcriptional regulator
D3093_RS24945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS24950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS24955	COG4948	Mandelate Racemase Muconate Lactonizing
D3093_RS24960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS24985	COG1126	abc transporter atp-binding protein
D3093_RS25010	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS25020	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS25025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3093_RS25075	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
D3093_RS25085	COG0189	ligase activity
D3093_RS25090	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
D3093_RS25100	COG0702	epimerase
D3093_RS25110	COG2154	pterin-4-alpha-carbinolamine dehydratase
D3093_RS25120	COG1229	Formylmethanofuran dehydrogenase subunit A
D3093_RS25125	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
D3093_RS25145	COG1131	(ABC) transporter
D3093_RS25205	COG2010	Cytochrome c
D3093_RS25230	COG1573	uracil-dna glycosylase
D3093_RS25250	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D3093_RS25265	COG0583	DNA-binding transcription factor activity
D3093_RS25290	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS25305	COG3842	ATPase activity
D3093_RS25335	COG1764	response to oxidative stress
D3093_RS25340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS25345	COG1960	acyl-CoA dehydrogenase activity
D3093_RS25350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3093_RS25420	COG0668	transmembrane transport
D3093_RS25460	COG1139	Iron-sulfur cluster binding protein
D3093_RS25465	COG0247	lactate metabolic process
D3093_RS25470	COG0277	FAD linked oxidase domain protein
D3093_RS25475	COG1620	l-lactate permease
D3093_RS25480	COG2186	Transcriptional regulator
D3093_RS25490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3093_RS25495	COG0542	response to heat
D3093_RS25500	COG1414	Transcriptional regulator
D3093_RS25505	COG3734	2-keto-3-deoxy-galactonokinase
D3093_RS25510	COG0800	Aldolase
D3093_RS25535	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS25560	COG0784	Response regulator, receiver
D3093_RS25560	COG5002	protein histidine kinase activity
D3093_RS25560	COG2205	protein histidine kinase activity
D3093_RS25570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS25610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3093_RS25615	COG4191	Histidine kinase
D3093_RS25620	COG4566	intracellular signal transduction
D3093_RS25630	COG0848	biopolymer transport protein
D3093_RS25670	COG3275	phosphorelay sensor kinase activity
D3093_RS25680	COG1966	Carbon starvation protein
D3093_RS25690	COG1363	Peptidase, m42
D3093_RS25695	COG2918	glutathione biosynthetic process
D3093_RS25695	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3093_RS25695	COG0189	ligase activity
D3093_RS25700	COG0367	asparagine synthase
D3093_RS25740	COG1802	Transcriptional regulator
D3093_RS25745	COG0517	IMP dehydrogenase activity
D3093_RS25745	COG0617	tRNA 3'-terminal CCA addition
D3093_RS25745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3093_RS25755	COG0861	Integral membrane protein TerC family
D3093_RS25825	COG2226	methyltransferase
D3093_RS25845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS25860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3093_RS25865	COG1846	Transcriptional regulator
D3093_RS25875	COG1309	transcriptional regulator
D3093_RS25880	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS25885	COG2186	Transcriptional regulator
D3093_RS25890	COG1960	acyl-CoA dehydrogenase activity
D3093_RS25900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3093_RS25935	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS25945	COG1960	acyl-CoA dehydrogenase activity
D3093_RS25950	COG0183	Belongs to the thiolase family
D3093_RS25955	COG1960	acyl-CoA dehydrogenase activity
D3093_RS25960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3093_RS25965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3093_RS25970	COG4770	biotin carboxylase activity
D3093_RS26035	COG2723	6-phospho-beta-galactosidase activity
D3093_RS26045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3093_RS26055	COG4178	(ABC) transporter
D3093_RS26065	COG1442	glycosyl transferase family 8
D3093_RS26065	COG1216	Glycosyl transferase, family 2
D3093_RS26110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS26125	COG2197	response regulator
D3093_RS26135	COG2198	Histidine kinase
D3093_RS26135	COG0643	Histidine kinase
D3093_RS26145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3093_RS26155	COG2201	protein-glutamate methylesterase activity
D3093_RS26160	COG0835	chemotaxis
D3093_RS26180	COG2095	MarC family integral membrane protein
D3093_RS26205	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS26210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D3093_RS26225	COG0395	ABC-type sugar transport system, permease component
D3093_RS26235	COG3842	ATPase activity
D3093_RS26250	COG0586	Pfam SNARE associated Golgi protein
D3093_RS26270	COG4615	Cyclic peptide transporter
D3093_RS26300	COG0840	transmembrane signaling receptor activity
D3093_RS26305	COG3290	protein histidine kinase activity
D3093_RS26305	COG0840	transmembrane signaling receptor activity
D3093_RS26340	COG5002	protein histidine kinase activity
D3093_RS26340	COG0784	Response regulator, receiver
D3093_RS26345	COG0784	Response regulator, receiver
D3093_RS26345	COG4191	Histidine kinase
D3093_RS26360	COG2388	GCN5-related N-acetyl-transferase
D3093_RS26365	COG0366	Alpha amylase catalytic
D3093_RS26370	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS26395	COG3290	protein histidine kinase activity
D3093_RS26395	COG0840	transmembrane signaling receptor activity
D3093_RS26400	COG1971	Probably functions as a manganese efflux pump
D3093_RS26430	COG4122	O-methyltransferase activity
D3093_RS26445	COG1473	amidohydrolase
D3093_RS26450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS26490	COG0840	transmembrane signaling receptor activity
D3093_RS26490	COG0840	transmembrane signaling receptor activity
D3093_RS26515	COG3842	ATPase activity
D3093_RS26530	COG1653	transport
D3093_RS26575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D3093_RS26585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3093_RS26605	COG0243	molybdopterin cofactor binding
D3093_RS26630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS26635	COG1116	anion transmembrane transporter activity
D3093_RS26640	COG0402	S-adenosylhomocysteine deaminase activity
D3093_RS26655	COG0154	amidase activity
D3093_RS26680	COG3842	ATPase activity
D3093_RS26690	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS26700	COG2351	hydroxyisourate hydrolase activity
D3093_RS26710	COG0154	amidase activity
D3093_RS26715	COG0784	Response regulator, receiver
D3093_RS26715	COG5002	protein histidine kinase activity
D3093_RS26755	COG3387	PFAM Glycoside hydrolase 15-related
D3093_RS26765	COG2197	response regulator
D3093_RS26770	COG2197	response regulator
D3093_RS26775	COG2197	response regulator
D3093_RS26785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3093_RS26790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS26795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS26800	COG0438	transferase activity, transferring glycosyl groups
D3093_RS26820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS26840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS26955	COG4383	Mu-like prophage protein gp29
D3093_RS26975	COG4397	Mu-like prophage major head subunit gpT
D3093_RS27050	COG0148	phosphopyruvate hydratase activity
D3093_RS27060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3093_RS27070	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS27075	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D3093_RS27080	COG1802	Transcriptional regulator
D3093_RS27100	COG0668	transmembrane transport
D3093_RS27175	COG2226	methyltransferase
D3093_RS27175	COG0596	Alpha beta hydrolase
D3093_RS27175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3093_RS27180	COG0183	Belongs to the thiolase family
D3093_RS27185	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS27195	COG2814	Major facilitator Superfamily
D3093_RS27200	COG0583	DNA-binding transcription factor activity
D3093_RS27210	COG5001	Diguanylate cyclase
D3093_RS27210	COG3300	MHYT domain
D3093_RS27215	COG0012	GTP binding
D3093_RS27235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS27235	COG2205	protein histidine kinase activity
D3093_RS27240	COG2201	protein-glutamate methylesterase activity
D3093_RS27245	COG2201	protein-glutamate methylesterase activity
D3093_RS27255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3093_RS27255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3093_RS27275	COG4251	negative regulation of phosphorylation
D3093_RS27280	COG0745	RESPONSE REGULATOR receiver
D3093_RS27285	COG0745	RESPONSE REGULATOR receiver
D3093_RS27320	COG1131	(ABC) transporter
D3093_RS27345	COG2011	ABC-type metal ion transport system permease component
D3093_RS27350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3093_RS27355	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS27375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3093_RS27375	COG2010	Cytochrome c
D3093_RS27380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3093_RS27395	COG1254	Belongs to the acylphosphatase family
D3093_RS27420	COG2239	Acts as a magnesium transporter
D3093_RS27425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS27425	COG2022	thiamine diphosphate biosynthetic process
D3093_RS27435	COG2022	thiamine diphosphate biosynthetic process
D3093_RS27490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3093_RS27495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D3093_RS27505	COG0191	fructose-bisphosphate aldolase activity
D3093_RS27520	COG0348	domain, Protein
D3093_RS27535	COG4251	negative regulation of phosphorylation
D3093_RS27540	COG0784	Response regulator, receiver
D3093_RS27585	COG1595	DNA-templated transcription, initiation
D3093_RS27590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3093_RS27595	COG1045	serine acetyltransferase
D3093_RS27620	COG3842	ATPase activity
D3093_RS27625	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS27630	COG1178	ABC-type Fe3 transport system permease component
D3093_RS27640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3093_RS27645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3093_RS27650	COG2233	PERMEase
D3093_RS27660	COG0747	negative chemotaxis
D3093_RS27665	COG0601	transmembrane transport
D3093_RS27680	COG4608	Belongs to the ABC transporter superfamily
D3093_RS27685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3093_RS27705	COG1744	ABC transporter substrate-binding protein PnrA-like
D3093_RS27740	COG0484	heat shock protein binding
D3093_RS27750	COG0564	pseudouridine synthase activity
D3093_RS27765	COG0156	8-amino-7-oxononanoate synthase activity
D3093_RS27775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3093_RS27775	COG4106	trans-aconitate 2-methyltransferase activity
D3093_RS27780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3093_RS27785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3093_RS27795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3093_RS27795	COG0574	Belongs to the PEP-utilizing enzyme family
D3093_RS27810	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D3093_RS27815	COG1278	Cold shock
D3093_RS27820	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS27840	COG1496	oxidoreductase activity
D3093_RS27850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3093_RS27855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3093_RS27865	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3093_RS27870	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3093_RS27875	COG1129	ABC transporter
D3093_RS27880	COG1879	ABC-type sugar transport system periplasmic component
D3093_RS27915	COG4214	carbohydrate transport
D3093_RS27925	COG0129	dihydroxy-acid dehydratase activity
D3093_RS27940	COG0246	Mannitol dehydrogenase
D3093_RS27945	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3093_RS27960	COG5039	Polysaccharide pyruvyl transferase
D3093_RS27965	COG2132	Multicopper oxidase
D3093_RS27975	COG1309	transcriptional regulator
D3093_RS27980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS27985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS27990	COG0702	epimerase
D3093_RS27995	COG1733	regulation of RNA biosynthetic process
D3093_RS28005	COG0583	DNA-binding transcription factor activity
D3093_RS28020	COG2133	pyrroloquinoline quinone binding
D3093_RS28055	COG1312	Catalyzes the dehydration of D-mannonate
D3093_RS28060	COG0246	Mannitol dehydrogenase
D3093_RS28075	COG1802	Transcriptional regulator
D3093_RS28080	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS28085	COG1917	Cupin 2, conserved barrel domain protein
D3093_RS28090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS28100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS28105	COG0667	Aldo Keto reductase
D3093_RS28110	COG1802	Transcriptional regulator
D3093_RS28115	COG1803	Methylglyoxal synthase
D3093_RS28120	COG1904	glucuronate isomerase
D3093_RS28125	COG2721	sulfolactate sulfo-lyase activity
D3093_RS28160	COG0861	Integral membrane protein TerC family
D3093_RS28200	COG4166	transmembrane transport
D3093_RS28210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS28215	COG0798	PFAM Bile acid sodium symporter
D3093_RS28230	COG2188	Transcriptional regulator
D3093_RS28245	COG0154	amidase activity
D3093_RS28260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS28265	COG1960	acyl-CoA dehydrogenase activity
D3093_RS28270	COG2079	MmgE PrpD family protein
D3093_RS28290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS28295	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS28310	COG1595	DNA-templated transcription, initiation
D3093_RS28340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3093_RS28385	COG1132	(ABC) transporter
D3093_RS28390	COG0784	Response regulator, receiver
D3093_RS28390	COG4191	Histidine kinase
D3093_RS28400	COG2203	Gaf domain
D3093_RS28400	COG2199	diguanylate cyclase activity
D3093_RS28420	COG0405	Gamma-glutamyltransferase
D3093_RS28450	COG1858	cytochrome C peroxidase
D3093_RS28475	COG4964	Belongs to the GSP D family
D3093_RS28605	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D3093_RS28630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3093_RS28640	COG3845	ABC transporter
D3093_RS28650	COG4603	Belongs to the binding-protein-dependent transport system permease family
D3093_RS28655	COG1079	Belongs to the binding-protein-dependent transport system permease family
D3093_RS28660	COG0402	S-adenosylhomocysteine deaminase activity
D3093_RS28665	COG0840	transmembrane signaling receptor activity
D3093_RS28675	COG4191	Histidine kinase
D3093_RS28700	COG1414	Transcriptional regulator
D3093_RS28705	COG3383	formate dehydrogenase (NAD+) activity
D3093_RS28725	COG1597	lipid kinase activity
D3093_RS28725	COG1803	Methylglyoxal synthase
D3093_RS28735	COG0628	permease
D3093_RS28740	COG3416	Protein conserved in bacteria
D3093_RS28785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3093_RS28795	COG1338	Plays a role in the flagellum-specific transport system
D3093_RS28800	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3093_RS28810	COG1766	The M ring may be actively involved in energy transduction
D3093_RS28845	COG3005	denitrification pathway
D3093_RS28855	COG0243	molybdopterin cofactor binding
D3093_RS28875	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D3093_RS28880	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
D3093_RS28885	COG4786	Flagellar basal body rod
D3093_RS28890	COG4786	Flagellar basal body rod
D3093_RS28900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3093_RS28905	COG1360	Flagellar Motor Protein
D3093_RS28975	COG2204	response regulator
D3093_RS28980	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS28980	COG1454	alcohol dehydrogenase
D3093_RS28995	COG0588	phosphoglycerate mutase activity
D3093_RS29005	COG3842	ATPase activity
D3093_RS29020	COG2985	domain, Protein
D3093_RS29030	COG2204	response regulator
D3093_RS29035	COG4191	Histidine kinase
D3093_RS29045	COG3300	MHYT domain
D3093_RS29045	COG5001	Diguanylate cyclase
D3093_RS29070	COG1522	sequence-specific DNA binding
D3093_RS29080	COG0028	Belongs to the TPP enzyme family
D3093_RS29090	COG4191	Histidine kinase
D3093_RS29100	COG5487	UPF0391 membrane protein
D3093_RS29105	COG0793	Belongs to the peptidase S41A family
D3093_RS29110	COG0583	DNA-binding transcription factor activity
D3093_RS29115	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS29125	COG0583	DNA-binding transcription factor activity
D3093_RS29130	COG0028	Belongs to the TPP enzyme family
D3093_RS29135	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS29160	COG4191	Histidine kinase
D3093_RS29160	COG0784	Response regulator, receiver
D3093_RS29165	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
D3093_RS29195	COG0583	DNA-binding transcription factor activity
D3093_RS29200	COG2855	membrane
D3093_RS29215	COG0546	phosphoglycolate phosphatase activity
D3093_RS29235	COG1192	Involved in chromosome partitioning
D3093_RS29240	COG1475	DNA binding
D3093_RS29250	COG0028	Belongs to the TPP enzyme family
D3093_RS29265	COG0437	4 iron, 4 sulfur cluster binding
D3093_RS29275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3093_RS29285	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS29305	COG0280	phosphate acetyltransferase
D3093_RS29310	COG1414	Transcriptional regulator
D3093_RS29315	COG1414	Transcriptional regulator
D3093_RS29325	COG1522	sequence-specific DNA binding
D3093_RS29330	COG0251	oxidation-reduction process
D3093_RS29335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3093_RS29380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS29395	COG0583	DNA-binding transcription factor activity
D3093_RS29425	COG2197	response regulator
D3093_RS29430	COG3920	Histidine kinase
D3093_RS29440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3093_RS29440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3093_RS29445	COG1105	Belongs to the carbohydrate kinase PfkB family
D3093_RS29450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3093_RS29450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3093_RS29455	COG1609	Transcriptional regulator
D3093_RS29465	COG1335	isochorismatase
D3093_RS29470	COG2309	aminopeptidase activity
D3093_RS29475	COG0596	Alpha beta hydrolase
D3093_RS29480	COG3473	Maleate cis-trans isomerase
D3093_RS29510	COG0683	leucine binding
D3093_RS29530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3093_RS29590	COG0154	amidase activity
D3093_RS29620	COG2204	response regulator
D3093_RS29620	COG5564	TIM-barrel signal transduction protein
D3093_RS29625	COG5441	Belongs to the UPF0261 family
D3093_RS29630	COG5564	TIM-barrel signal transduction protein
D3093_RS29645	COG2086	electron transfer activity
D3093_RS29650	COG0277	FAD linked oxidase domain protein
D3093_RS29665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3093_RS29680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D3093_RS29685	COG0567	Dehydrogenase, E1 component
D3093_RS29705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS29710	COG1845	cytochrome c oxidase, subunit III
D3093_RS29720	COG2186	Transcriptional regulator
D3093_RS29725	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3093_RS29730	COG2267	carboxylic ester hydrolase activity
D3093_RS29775	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D3093_RS29785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3093_RS29790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS29795	COG1120	ATPase activity
D3093_RS29800	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
D3093_RS29805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3093_RS29820	COG1802	Transcriptional regulator
D3093_RS29825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3093_RS29845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3093_RS29855	COG5443	negative regulation of bacterial-type flagellum assembly
D3093_RS29875	COG2814	Major facilitator Superfamily
D3093_RS29895	COG1815	bacterial-type flagellum-dependent cell motility
D3093_RS29900	COG1558	bacterial-type flagellum-dependent cell motility
D3093_RS29905	COG1677	Flagellar hook-basal body complex protein FliE
D3093_RS29910	COG4794	Type iii secretion
D3093_RS29920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3093_RS29925	COG1684	flagellar biosynthetic protein fliR
D3093_RS29930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3093_RS29960	COG1706	bacterial-type flagellum-dependent cell motility
D3093_RS29975	COG1749	Flagellar hook protein flgE
D3093_RS30005	COG0861	Integral membrane protein TerC family
D3093_RS30010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS30020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS30030	COG1802	Transcriptional regulator
D3093_RS30035	COG0697	spore germination
D3093_RS30040	COG2116	formate transmembrane transporter activity
D3093_RS30045	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3093_RS30050	COG0469	pyruvate kinase activity
D3093_RS30055	COG4251	negative regulation of phosphorylation
D3093_RS30060	COG5002	protein histidine kinase activity
D3093_RS30065	COG1309	transcriptional regulator
D3093_RS30070	COG1309	transcriptional regulator
D3093_RS30075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS30080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3093_RS30085	COG0837	glucose binding
D3093_RS30085	COG1737	Transcriptional regulator
D3093_RS30090	COG1882	Formate acetyltransferase
D3093_RS30125	COG2842	Transposition protein
D3093_RS30240	COG4383	Mu-like prophage protein gp29
D3093_RS30265	COG1192	Involved in chromosome partitioning
D3093_RS30275	COG1802	Transcriptional regulator
D3093_RS30275	COG4626	Terminase
D3093_RS30315	COG4774	siderophore transport
D3093_RS30325	COG1595	DNA-templated transcription, initiation
D3093_RS30345	COG0765	amino acid transport
D3093_RS30355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3093_RS30365	COG1126	abc transporter atp-binding protein
D3093_RS30380	COG2115	Belongs to the xylose isomerase family
D3093_RS30385	COG0673	inositol 2-dehydrogenase activity
D3093_RS30395	COG1879	ABC-type sugar transport system periplasmic component
D3093_RS30400	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3093_RS30410	COG1940	carbohydrate kinase activity
D3093_RS30420	COG0631	protein serine/threonine phosphatase activity
D3093_RS30510	COG0631	protein serine/threonine phosphatase activity
D3093_RS30550	COG1121	(ABC) transporter
D3093_RS30565	COG1136	(ABC) transporter
D3093_RS30565	COG0577	efflux transmembrane transporter activity
D3093_RS30570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS30585	COG1595	DNA-templated transcription, initiation
D3093_RS30605	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS30630	COG1053	succinate dehydrogenase
D3093_RS30650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS30655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D3093_RS30665	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS30675	COG2301	Belongs to the HpcH HpaI aldolase family
D3093_RS30680	COG2072	flavoprotein involved in K transport
D3093_RS30700	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3093_RS30700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3093_RS30710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS30760	COG4774	siderophore transport
D3093_RS30765	COG1120	ATPase activity
D3093_RS30775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS30780	COG1132	(ABC) transporter
D3093_RS30810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3093_RS30815	COG0402	S-adenosylhomocysteine deaminase activity
D3093_RS30830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3093_RS30840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS30850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3093_RS30855	COG1129	ABC transporter
D3093_RS30855	COG0842	Transport permease protein
D3093_RS30860	COG0842	Transport permease protein
D3093_RS30870	COG3721	Heme iron utilization protein
D3093_RS30880	COG0745	RESPONSE REGULATOR receiver
D3093_RS30885	COG1120	ATPase activity
D3093_RS30890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS30900	COG3720	iron ion transport
D3093_RS30910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3093_RS30935	COG0583	DNA-binding transcription factor activity
D3093_RS30945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3093_RS30945	COG1017	nitric oxide dioxygenase activity
D3093_RS30950	COG0625	glutathione transferase activity
D3093_RS30955	COG1802	Transcriptional regulator
D3093_RS30965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3093_RS30985	COG2197	response regulator
D3093_RS30995	COG0625	glutathione transferase activity
D3093_RS31010	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS31040	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS31045	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3093_RS31050	COG1053	succinate dehydrogenase
D3093_RS31060	COG0673	inositol 2-dehydrogenase activity
D3093_RS31080	COG0431	NADPH-dependent FMN reductase
D3093_RS31080	COG1053	succinate dehydrogenase
D3093_RS31080	COG3976	FMN-binding domain protein
D3093_RS31085	COG1902	pentaerythritol trinitrate reductase activity
D3093_RS31090	COG1053	succinate dehydrogenase
D3093_RS31100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3093_RS31110	COG0765	amino acid transport
D3093_RS31115	COG1126	abc transporter atp-binding protein
D3093_RS31120	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS31125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3093_RS31130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3093_RS31140	COG2721	sulfolactate sulfo-lyase activity
D3093_RS31165	COG0745	RESPONSE REGULATOR receiver
D3093_RS31195	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS31200	COG1024	Enoyl-CoA hydratase
D3093_RS31205	COG0022	dehydrogenase e1 component
D3093_RS31205	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3093_RS31210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3093_RS31220	COG0683	leucine binding
D3093_RS31255	COG0183	Belongs to the thiolase family
D3093_RS31285	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3093_RS31385	COG3842	ATPase activity
D3093_RS31390	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS31395	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS31400	COG3938	Belongs to the proline racemase family
D3093_RS31405	COG1802	Transcriptional regulator
D3093_RS31410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D3093_RS31415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3093_RS31420	COG0066	3-isopropylmalate dehydratase activity
D3093_RS31435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS31495	COG3842	ATPase activity
D3093_RS31505	COG1349	DNA-binding transcription factor activity
D3093_RS31530	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS31545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS31555	COG1024	Enoyl-CoA hydratase
D3093_RS31560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS31565	COG0154	amidase activity
D3093_RS31595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3093_RS31600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3093_RS31605	COG0697	spore germination
D3093_RS31620	COG2188	Transcriptional regulator
D3093_RS31645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3093_RS31695	COG4772	TonB-dependent receptor
D3093_RS31720	COG3842	ATPase activity
D3093_RS31740	COG0318	PFAM AMP-dependent synthetase and ligase
D3093_RS31745	COG1024	Enoyl-CoA hydratase
D3093_RS31750	COG0604	alcohol dehydrogenase
D3093_RS31760	COG1414	Transcriptional regulator
D3093_RS31770	COG0601	transmembrane transport
D3093_RS31775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3093_RS31780	COG0444	Belongs to the ABC transporter superfamily
D3093_RS31785	COG4608	Belongs to the ABC transporter superfamily
D3093_RS31805	COG3250	beta-galactosidase activity
D3093_RS31810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3093_RS31815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3093_RS31815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3093_RS31835	COG0861	Integral membrane protein TerC family
D3093_RS31840	COG0251	oxidation-reduction process
D3093_RS31850	COG0251	oxidation-reduction process
D3093_RS31855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3093_RS31875	COG1177	transmembrane transport
D3093_RS31880	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3093_RS31885	COG3842	ATPase activity
D3093_RS31900	COG1126	abc transporter atp-binding protein
D3093_RS31905	COG0765	amino acid transport
D3093_RS31915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3093_RS31925	COG0277	FAD linked oxidase domain protein
D3093_RS31930	COG1396	sequence-specific DNA binding
D3093_RS31960	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS31965	COG3246	L-lysine catabolic process to acetate
D3093_RS31970	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3093_RS31975	COG2204	response regulator
D3093_RS31995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3093_RS32000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3093_RS32010	COG4566	intracellular signal transduction
D3093_RS32010	COG0745	RESPONSE REGULATOR receiver
D3093_RS32025	COG0411	ABC transporter
D3093_RS32040	COG0683	leucine binding
D3093_RS32045	COG2814	Major facilitator Superfamily
D3093_RS32055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3093_RS32060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS32090	COG0633	Ferredoxin
D3093_RS32095	COG2124	cytochrome p450
D3093_RS32110	COG0583	DNA-binding transcription factor activity
D3093_RS32120	COG1595	DNA-templated transcription, initiation
D3093_RS32125	COG4774	siderophore transport
D3093_RS32140	COG4774	siderophore transport
D3093_RS32160	COG1120	ATPase activity
D3093_RS32180	COG2271	Major facilitator Superfamily
D3093_RS32185	COG0583	DNA-binding transcription factor activity
D3093_RS32215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS32230	COG0826	peptidase U32
D3093_RS32255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3093_RS32270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3093_RS32290	COG4263	nitrous-oxide reductase activity
D3093_RS32310	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3093_RS32330	COG1053	succinate dehydrogenase
D3093_RS32330	COG0431	NADPH-dependent FMN reductase
D3093_RS32330	COG3976	FMN-binding domain protein
D3093_RS32335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS32345	COG1012	belongs to the aldehyde dehydrogenase family
D3093_RS32360	COG0583	DNA-binding transcription factor activity
D3093_RS32370	COG2814	Major facilitator Superfamily
D3093_RS32380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3093_RS32385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3093_RS32390	COG2080	2 iron, 2 sulfur cluster binding
D3093_RS32405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D3093_RS32415	COG0714	Associated with various cellular activities
D3093_RS32450	COG3119	arylsulfatase activity
D3093_RS32475	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32485	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32485	COG3321	synthase
D3093_RS32485	COG0604	alcohol dehydrogenase
D3093_RS32555	COG2207	Transcriptional regulator
D3093_RS32570	COG1566	PFAM secretion protein HlyD family protein
D3093_RS32580	COG0765	amino acid transport
D3093_RS32585	COG4597	amino acid ABC transporter
D3093_RS32600	COG0251	oxidation-reduction process
D3093_RS32605	COG3608	succinylglutamate desuccinylase aspartoacylase
D3093_RS32610	COG1609	Transcriptional regulator
D3093_RS32630	COG3425	synthase
D3093_RS32645	COG3321	synthase
D3093_RS32645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3093_RS32645	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32645	COG4221	oxidoreductase activity
D3093_RS32650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS32650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3093_RS32650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS32650	COG3321	synthase
D3093_RS32650	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32655	COG0300	oxidoreductase activity
D3093_RS32655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS32655	COG3321	synthase
D3093_RS32655	COG4221	oxidoreductase activity
D3093_RS32660	COG2072	flavoprotein involved in K transport
D3093_RS32665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3093_RS32675	COG1024	Enoyl-CoA hydratase
D3093_RS32680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS32690	COG0300	oxidoreductase activity
D3093_RS32690	COG4221	oxidoreductase activity
D3093_RS32690	COG3321	synthase
D3093_RS32690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS32695	COG4221	oxidoreductase activity
D3093_RS32695	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3093_RS32695	COG3321	synthase
D3093_RS32700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS32700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3093_RS32700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3093_RS32700	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS32700	COG3321	synthase
D3093_RS32720	COG4521	taurine ABC transporter
D3093_RS32725	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D3093_RS32730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS32735	COG3119	arylsulfatase activity
D3093_RS32740	COG2175	clavaminate synthase activity
D3093_RS32750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3093_RS32755	COG1116	anion transmembrane transporter activity
D3093_RS32775	COG0714	Associated with various cellular activities
D3093_RS32780	COG3256	nitric oxide reductase
D3093_RS32830	COG0534	Mate efflux family protein
D3093_RS32855	COG3344	reverse transcriptase
D3093_RS32865	COG3328	transposase activity
D3093_RS32895	COG0210	DNA helicase
D3093_RS32900	COG1192	Involved in chromosome partitioning
D3093_RS32905	COG1475	DNA binding
D3093_RS32910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS32955	COG4974	Belongs to the 'phage' integrase family
D3093_RS32965	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3093_RS32975	COG2086	electron transfer activity
D3093_RS32980	COG0840	transmembrane signaling receptor activity
D3093_RS33005	COG1024	Enoyl-CoA hydratase
D3093_RS33010	COG1960	acyl-CoA dehydrogenase activity
D3093_RS33025	COG2084	Dehydrogenase
D3093_RS33035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS33050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS33060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3093_RS33090	COG1028	Short-chain dehydrogenase reductase Sdr
D3093_RS33100	COG1881	PFAM PEBP family protein
D3093_RS33135	COG2205	protein histidine kinase activity
D3093_RS33165	COG2376	Dihydroxyacetone kinase
D3093_RS33175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3093_RS33180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3093_RS33200	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3093_RS33205	COG1879	ABC-type sugar transport system periplasmic component
D3093_RS33210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3093_RS33245	COG1132	(ABC) transporter
D3093_RS33245	COG2375	cellular response to nickel ion
D3093_RS33250	COG1132	(ABC) transporter
D3093_RS33255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3093_RS33260	COG4605	iron ion homeostasis
D3093_RS33265	COG4604	ABC transporter, ATP-binding protein
D3093_RS33270	COG4607	ABC-type enterochelin transport system periplasmic component
D3093_RS33275	COG4774	siderophore transport
D3093_RS33285	COG1404	Belongs to the peptidase S8 family
D3093_RS33420	COG0531	amino acid
D3093_RS33440	COG3485	protocatechuate 3,4-dioxygenase
D3093_RS33460	COG1518	maintenance of DNA repeat elements
D3093_RS33490	COG1203	CRISPR-associated helicase, Cas3
D3093_RS33570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3093_RS33635	COG0583	DNA-binding transcription factor activity
D3093_RS33650	COG1846	Transcriptional regulator
D3093_RS33710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS33860	COG1396	sequence-specific DNA binding
D3093_RS33905	COG3177	Filamentation induced by cAMP protein fic
D3093_RS33940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3093_RS33940	COG0551	DNA topoisomerase type I activity
D3093_RS33955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3093_RS34025	COG2963	transposase activity
D3093_RS34030	COG3549	Plasmid maintenance system killer
D3093_RS34145	COG3550	peptidyl-serine autophosphorylation
D3093_RS34155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS34160	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
D3093_RS34195	COG3451	type IV secretory pathway VirB4
D3093_RS34305	COG1509	lysine 2,3-aminomutase activity
D3093_RS34310	COG2175	clavaminate synthase activity
D3093_RS34330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D3093_RS34360	COG0534	Mate efflux family protein
D3093_RS34430	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS34450	COG0438	transferase activity, transferring glycosyl groups
D3093_RS34475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS34540	COG0438	transferase activity, transferring glycosyl groups
D3093_RS34545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D3093_RS34565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3093_RS34570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D3093_RS34585	COG2895	sulfate adenylyltransferase (ATP) activity
D3093_RS34585	COG0529	Catalyzes the synthesis of activated sulfate
D3093_RS34590	COG0175	sulfate reduction
D3093_RS34625	COG0500	methyltransferase
D3093_RS34635	COG0438	transferase activity, transferring glycosyl groups
D3093_RS34635	COG1216	Glycosyl transferase, family 2
D3093_RS34640	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D3093_RS34650	COG1091	dTDP-4-dehydrorhamnose reductase activity
D3093_RS34655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3093_RS34670	COG0438	transferase activity, transferring glycosyl groups
D3093_RS34670	COG1216	Glycosyl transferase, family 2
D3093_RS34715	COG2226	methyltransferase
D3093_RS34720	COG0528	UMP kinase activity
D3093_RS34725	COG0528	UMP kinase activity
D3093_RS34745	COG0494	nUDIX hydrolase
D3093_RS34760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3093_RS34770	COG1086	Polysaccharide biosynthesis protein
D3093_RS34785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3093_RS34795	COG1475	DNA binding
D3093_RS34800	COG1192	Involved in chromosome partitioning
D3093_RS34810	COG0579	oxidoreductase
D3093_RS34825	COG2274	protein secretion by the type I secretion system
D3093_RS34840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3093_RS34870	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D3093_RS34900	COG1216	Glycosyl transferase, family 2
D3093_RS34900	COG0463	Glycosyl transferase, family 2
D3093_RS34905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3093_RS34920	COG2089	acid synthase
D3093_RS34925	COG0367	asparagine synthase
D3093_RS34930	COG0438	transferase activity, transferring glycosyl groups
D3093_RS35065	COG3547	Transposase (IS116 IS110 IS902 family)
D3093_RS35085	COG0741	lytic transglycosylase activity
D3093_RS35125	COG3772	lysozyme
D3093_RS35200	COG0604	alcohol dehydrogenase
D3093_RS35205	COG1733	regulation of RNA biosynthetic process
D3093_RS35290	COG0328	RNA-DNA hybrid ribonuclease activity
D3093_RS35315	COG1396	sequence-specific DNA binding
D3093_RS35370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3093_RS35410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3093_RS35505	COG0305	Participates in initiation and elongation during chromosome replication
D3093_RS35545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3093_RS35550	COG1518	maintenance of DNA repeat elements
D3093_RS35565	COG1857	crispr-associated protein
D3093_RS35580	COG1203	CRISPR-associated helicase, Cas3
D3093_RS35775	COG3328	transposase activity
D3093_RS35785	COG2226	methyltransferase
D3093_RS35805	COG1783	phage Terminase large subunit