locus-tag	class	description
AL072_RS00005	COG0523	cobalamin synthesis protein
AL072_RS00015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL072_RS00030	COG2205	protein histidine kinase activity
AL072_RS00040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL072_RS00045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL072_RS00045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL072_RS00060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL072_RS00060	COG0357	Ribosomal RNA small subunit methyltransferase G
AL072_RS00065	COG4251	negative regulation of phosphorylation
AL072_RS00070	COG0497	DNA recombination
AL072_RS00075	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL072_RS00080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL072_RS00090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AL072_RS00090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL072_RS00095	COG0243	molybdopterin cofactor binding
AL072_RS00125	COG4566	intracellular signal transduction
AL072_RS00130	COG2205	protein histidine kinase activity
AL072_RS00140	COG3108	Peptidase M15
AL072_RS00155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL072_RS00165	COG1648	precorrin-2 dehydrogenase activity
AL072_RS00165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL072_RS00170	COG0175	sulfate reduction
AL072_RS00185	COG0488	(ABC) transporter
AL072_RS00210	COG2070	2-Nitropropane dioxygenase
AL072_RS00215	COG3706	GGDEF domain
AL072_RS00255	COG1410	methionine synthase
AL072_RS00255	COG0646	methionine synthase
AL072_RS00280	COG2853	Lipoprotein
AL072_RS00310	COG0488	(ABC) transporter
AL072_RS00315	COG1671	Belongs to the UPF0178 family
AL072_RS00320	COG0277	FAD linked oxidase domain protein
AL072_RS00325	COG3199	ATP-NAD kinase
AL072_RS00330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL072_RS00335	COG0022	dehydrogenase e1 component
AL072_RS00340	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL072_RS00340	COG0596	Alpha beta hydrolase
AL072_RS00350	COG1063	alcohol dehydrogenase
AL072_RS00355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL072_RS00370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL072_RS00375	COG2205	protein histidine kinase activity
AL072_RS00380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL072_RS00385	COG2301	Belongs to the HpcH HpaI aldolase family
AL072_RS00395	COG0745	RESPONSE REGULATOR receiver
AL072_RS00430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL072_RS00435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL072_RS00440	COG0552	protein localization to endoplasmic reticulum
AL072_RS00445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL072_RS00455	COG0121	glutamine amidotransferase
AL072_RS00505	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AL072_RS00510	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AL072_RS00525	COG5420	small protein containing a coiled-coil domain
AL072_RS00530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL072_RS00540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL072_RS00550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL072_RS00565	COG1573	uracil-dna glycosylase
AL072_RS00570	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL072_RS00575	COG4948	Mandelate Racemase Muconate Lactonizing
AL072_RS00580	COG0840	transmembrane signaling receptor activity
AL072_RS00600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL072_RS00605	COG2894	cell division
AL072_RS00610	COG0850	regulation of cytokinetic process
AL072_RS00615	COG1702	phosphate starvation-inducible protein PhoH
AL072_RS00625	COG1999	signal sequence binding
AL072_RS00635	COG0356	it plays a direct role in the translocation of protons across the membrane
AL072_RS00640	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL072_RS00645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL072_RS00655	COG3384	dioxygenase
AL072_RS00660	COG5002	protein histidine kinase activity
AL072_RS00660	COG0784	Response regulator, receiver
AL072_RS00665	COG0235	Class ii aldolase
AL072_RS00690	COG0437	4 iron, 4 sulfur cluster binding
AL072_RS00695	COG3383	formate dehydrogenase (NAD+) activity
AL072_RS00695	COG0243	molybdopterin cofactor binding
AL072_RS00720	COG0746	molybdenum cofactor guanylyltransferase activity
AL072_RS00725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL072_RS00745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL072_RS00750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL072_RS00765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL072_RS00785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL072_RS00815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL072_RS00825	COG0612	Peptidase, M16
AL072_RS00830	COG0612	Peptidase, M16
AL072_RS00835	COG0166	Belongs to the GPI family
AL072_RS00850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL072_RS00860	COG2205	protein histidine kinase activity
AL072_RS00865	COG2205	protein histidine kinase activity
AL072_RS00870	COG2205	protein histidine kinase activity
AL072_RS00870	COG2202	Pas domain
AL072_RS00885	COG1686	Belongs to the peptidase S11 family
AL072_RS00910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL072_RS00935	COG1366	Belongs to the anti-sigma-factor antagonist family
AL072_RS00945	COG5002	protein histidine kinase activity
AL072_RS00945	COG0784	Response regulator, receiver
AL072_RS00945	COG2205	protein histidine kinase activity
AL072_RS00980	COG0501	Belongs to the peptidase M48B family
AL072_RS00985	COG5508	conserved small protein
AL072_RS00995	COG0395	ABC-type sugar transport system, permease component
AL072_RS01010	COG2205	protein histidine kinase activity
AL072_RS01025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL072_RS01035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL072_RS01050	COG2962	Rard protein
AL072_RS01060	COG1902	pentaerythritol trinitrate reductase activity
AL072_RS01105	COG2204	response regulator
AL072_RS01115	COG0644	oxidoreductase
AL072_RS01120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AL072_RS01130	COG0784	Response regulator, receiver
AL072_RS01130	COG5002	protein histidine kinase activity
AL072_RS01130	COG2205	protein histidine kinase activity
AL072_RS01150	COG1663	tetraacyldisaccharide 4'-kinase activity
AL072_RS01155	COG1519	Transferase
AL072_RS01170	COG1280	lysine exporter protein (LysE YggA)
AL072_RS01190	COG1597	lipid kinase activity
AL072_RS01200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL072_RS01205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL072_RS01235	COG0628	permease
AL072_RS01245	COG2267	carboxylic ester hydrolase activity
AL072_RS01250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL072_RS01255	COG2030	dehydratase
AL072_RS01260	COG0196	riboflavin kinase activity
AL072_RS01265	COG2814	Major facilitator Superfamily
AL072_RS01270	COG1285	pathogenesis
AL072_RS01320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL072_RS01335	COG2873	o-acetylhomoserine
AL072_RS01345	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL072_RS01370	COG0563	adenylate kinase activity
AL072_RS01375	COG0201	protein transport
AL072_RS01380	COG0200	Binds to the 23S rRNA
AL072_RS01385	COG1841	ribosomal large subunit assembly
AL072_RS01390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL072_RS01400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL072_RS01405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL072_RS01410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL072_RS01420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL072_RS01430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL072_RS01435	COG0255	Belongs to the universal ribosomal protein uL29 family
AL072_RS01440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL072_RS01445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL072_RS01450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL072_RS01455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL072_RS01460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL072_RS01465	COG0089	rRNA binding
AL072_RS01470	COG0088	Forms part of the polypeptide exit tunnel
AL072_RS01475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL072_RS01480	COG0051	transcription antitermination factor activity, RNA binding
AL072_RS01485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL072_RS01495	COG0049	tRNA binding
AL072_RS01505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL072_RS01510	COG0085	RNA polymerase activity
AL072_RS01515	COG0222	ribosome binding
AL072_RS01520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL072_RS01525	COG0081	regulation of translation
AL072_RS01530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL072_RS01550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL072_RS01640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL072_RS01645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL072_RS01680	COG1940	carbohydrate kinase activity
AL072_RS01730	COG1530	ribonuclease E activity
AL072_RS01740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL072_RS01745	COG0598	Magnesium transport protein CorA
AL072_RS01755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL072_RS01765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL072_RS01770	COG0706	membrane insertase activity
AL072_RS01775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL072_RS01785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL072_RS01790	COG0335	large ribosomal subunit rRNA binding
AL072_RS01800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL072_RS01805	COG0228	four-way junction DNA binding
AL072_RS01810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL072_RS01850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL072_RS01870	COG1960	acyl-CoA dehydrogenase activity
AL072_RS01880	COG1454	alcohol dehydrogenase
AL072_RS01900	COG0247	lactate metabolic process
AL072_RS01905	COG0277	FAD linked oxidase domain protein
AL072_RS01910	COG0277	FAD linked oxidase domain protein
AL072_RS01915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL072_RS01935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL072_RS01940	COG0745	RESPONSE REGULATOR receiver
AL072_RS01945	COG2205	protein histidine kinase activity
AL072_RS01960	COG3108	Peptidase M15
AL072_RS01965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL072_RS01985	COG4191	Histidine kinase
AL072_RS01995	COG4106	trans-aconitate 2-methyltransferase activity
AL072_RS02010	COG0126	phosphoglycerate kinase activity
AL072_RS02025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL072_RS02035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL072_RS02045	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL072_RS02050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL072_RS02060	COG2010	Cytochrome c
AL072_RS02060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL072_RS02065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL072_RS02090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL072_RS02095	COG0640	Transcriptional regulator
AL072_RS02105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL072_RS02210	COG1058	Belongs to the CinA family
AL072_RS02210	COG1546	Belongs to the CinA family
AL072_RS02215	COG1489	DNA binding
AL072_RS02220	COG0024	Methionine aminopeptidase
AL072_RS02240	COG0514	ATP-dependent DNA helicase (RecQ)
AL072_RS02245	COG0494	nUDIX hydrolase
AL072_RS02250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL072_RS02255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL072_RS02260	COG0653	protein targeting
AL072_RS02265	COG1970	mechanosensitive ion channel activity
AL072_RS02285	COG0640	Transcriptional regulator
AL072_RS02315	COG0039	L-malate dehydrogenase activity
AL072_RS02320	COG0045	succinate-CoA ligase (ADP-forming) activity
AL072_RS02325	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL072_RS02350	COG4191	Histidine kinase
AL072_RS02385	COG1643	Atp-dependent helicase
AL072_RS02390	COG0574	Belongs to the PEP-utilizing enzyme family
AL072_RS02390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL072_RS02400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL072_RS02410	COG0539	negative regulation of cytoplasmic translation
AL072_RS02520	COG4372	Transposase
AL072_RS02530	COG2433	Pfam Transposase IS66
AL072_RS02535	COG3436	PFAM IS66 Orf2 family protein
AL072_RS02550	COG2963	transposase activity
AL072_RS02555	COG2433	Pfam Transposase IS66
AL072_RS02560	COG3436	PFAM IS66 Orf2 family protein
AL072_RS02590	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AL072_RS02595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL072_RS02610	COG3177	Filamentation induced by cAMP protein fic
AL072_RS02665	COG0433	COG0433 Predicted ATPase
AL072_RS02705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL072_RS02705	COG2755	lipolytic protein G-D-S-L family
AL072_RS02715	COG1238	metal cluster binding
AL072_RS02720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL072_RS02730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL072_RS02740	COG1674	ftsk spoiiie
AL072_RS02745	COG2318	DinB family
AL072_RS02755	COG2205	protein histidine kinase activity
AL072_RS02780	COG0243	molybdopterin cofactor binding
AL072_RS02790	COG3005	denitrification pathway
AL072_RS02810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL072_RS02815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL072_RS02825	COG1522	sequence-specific DNA binding
AL072_RS02830	COG3660	Nucleoside-diphosphate-sugar epimerase
AL072_RS02845	COG1793	dna ligase
AL072_RS02855	COG2313	pseudouridylate synthase activity
AL072_RS02870	COG0753	catalase activity
AL072_RS02880	COG1741	Belongs to the pirin family
AL072_RS02885	COG0004	ammonium transporteR
AL072_RS02890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL072_RS02895	COG0297	glycogen (starch) synthase activity
AL072_RS02920	COG0252	asparaginase activity
AL072_RS02930	COG0583	DNA-binding transcription factor activity
AL072_RS02940	COG0784	Response regulator, receiver
AL072_RS02940	COG3437	response regulator, receiver
AL072_RS02955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL072_RS02960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL072_RS02965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL072_RS02975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL072_RS02985	COG1187	pseudouridine synthase activity
AL072_RS02990	COG1960	acyl-CoA dehydrogenase activity
AL072_RS03000	COG2086	electron transfer activity
AL072_RS03005	COG0318	PFAM AMP-dependent synthetase and ligase
AL072_RS03020	COG3162	membrane
AL072_RS03025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL072_RS03035	COG2202	Pas domain
AL072_RS03035	COG2205	protein histidine kinase activity
AL072_RS03055	COG0247	lactate metabolic process
AL072_RS03060	COG1592	Rubrerythrin
AL072_RS03080	COG1509	lysine 2,3-aminomutase activity
AL072_RS03155	COG0745	RESPONSE REGULATOR receiver
AL072_RS03165	COG1234	tRNA 3'-trailer cleavage
AL072_RS03210	COG1715	Restriction endonuclease
AL072_RS03240	COG2944	sequence-specific DNA binding
AL072_RS03260	COG0587	DNA-directed DNA polymerase activity
AL072_RS03270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL072_RS03435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL072_RS03445	COG1715	Restriction endonuclease
AL072_RS03465	COG1872	DUF167
AL072_RS03470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL072_RS03475	COG0598	Magnesium transport protein CorA
AL072_RS03490	COG0039	L-malate dehydrogenase activity
AL072_RS03505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL072_RS03515	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL072_RS03525	COG1573	uracil-dna glycosylase
AL072_RS03535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL072_RS03540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL072_RS03555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL072_RS03560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL072_RS03570	COG0251	oxidation-reduction process
AL072_RS03575	COG1309	transcriptional regulator
AL072_RS03595	COG2223	nitrite transmembrane transporter activity
AL072_RS03615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL072_RS03615	COG0517	IMP dehydrogenase activity
AL072_RS03630	COG1137	ATPase activity
AL072_RS03635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL072_RS03640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL072_RS03645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL072_RS03650	COG4636	protein conserved in cyanobacteria
AL072_RS03660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL072_RS03670	COG2070	2-Nitropropane dioxygenase
AL072_RS03690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL072_RS03695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL072_RS03705	COG2852	Protein conserved in bacteria
AL072_RS03710	COG2890	protein-(glutamine-N5) methyltransferase activity
AL072_RS03725	COG0494	nUDIX hydrolase
AL072_RS03730	COG0542	response to heat
AL072_RS03735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL072_RS03765	COG3162	membrane
AL072_RS03785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL072_RS03795	COG1040	competence protein
AL072_RS03825	COG5001	Diguanylate cyclase
AL072_RS03835	COG1473	amidohydrolase
AL072_RS03840	COG0625	glutathione transferase activity
AL072_RS03845	COG3813	Protein conserved in bacteria
AL072_RS03850	COG0784	Response regulator, receiver
AL072_RS03850	COG3437	response regulator, receiver
AL072_RS03865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL072_RS03905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL072_RS03915	COG1024	Enoyl-CoA hydratase
AL072_RS03920	COG0268	Binds directly to 16S ribosomal RNA
AL072_RS03925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL072_RS03930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL072_RS03935	COG3842	ATPase activity
AL072_RS03970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL072_RS03990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL072_RS03995	COG2264	protein methyltransferase activity
AL072_RS04000	COG2270	Major facilitator Superfamily
AL072_RS04020	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL072_RS04075	COG0285	dihydrofolate synthase activity
AL072_RS04080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL072_RS04100	COG0133	tryptophan synthase activity
AL072_RS04105	COG0784	Response regulator, receiver
AL072_RS04105	COG2205	protein histidine kinase activity
AL072_RS04110	COG1278	Cold shock
AL072_RS04115	COG2204	response regulator
AL072_RS04120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL072_RS04130	COG0784	Response regulator, receiver
AL072_RS04130	COG5002	protein histidine kinase activity
AL072_RS04130	COG2205	protein histidine kinase activity
AL072_RS04135	COG2205	protein histidine kinase activity
AL072_RS04145	COG4974	Belongs to the 'phage' integrase family
AL072_RS04160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL072_RS04185	COG0271	Belongs to the BolA IbaG family
AL072_RS04205	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AL072_RS04210	COG0501	Belongs to the peptidase M48B family
AL072_RS04225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL072_RS04230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL072_RS04235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL072_RS04235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL072_RS04240	COG1660	Displays ATPase and GTPase activities
AL072_RS04255	COG0642	Histidine kinase
AL072_RS04260	COG0745	RESPONSE REGULATOR receiver
AL072_RS04270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL072_RS04320	COG4957	zinc ion binding
AL072_RS04340	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL072_RS04360	COG0443	Heat shock 70 kDa protein
AL072_RS04370	COG3706	GGDEF domain
AL072_RS04375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL072_RS04380	COG0667	Aldo Keto reductase
AL072_RS04395	COG4181	ATPase activity
AL072_RS04405	COG0670	Belongs to the BI1 family
AL072_RS04415	COG0745	RESPONSE REGULATOR receiver
AL072_RS04420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL072_RS04430	COG0573	inorganic phosphate transmembrane transporter activity
AL072_RS04435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL072_RS04440	COG5002	protein histidine kinase activity
AL072_RS04455	COG0281	malic enzyme
AL072_RS04455	COG0280	phosphate acetyltransferase
AL072_RS04460	COG2814	Major facilitator Superfamily
AL072_RS04465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL072_RS04470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL072_RS04475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL072_RS04495	COG0357	Ribosomal RNA small subunit methyltransferase G
AL072_RS04500	COG0445	tRNA wobble uridine modification
AL072_RS04505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL072_RS04520	COG1331	Highly conserved protein containing a thioredoxin domain
AL072_RS04535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL072_RS04570	COG1981	membrane
AL072_RS04575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL072_RS04580	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL072_RS04590	COG4395	Tim44
AL072_RS04595	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL072_RS04600	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL072_RS04660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL072_RS04665	COG4235	cytochrome complex assembly
AL072_RS04670	COG3088	subunit of a heme lyase
AL072_RS04675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL072_RS04680	COG1138	Cytochrome C-type biogenesis protein
AL072_RS04685	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL072_RS04695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL072_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS04720	COG1185	polyribonucleotide nucleotidyltransferase activity
AL072_RS04725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL072_RS04730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL072_RS04735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL072_RS04755	COG0779	Required for maturation of 30S ribosomal subunits
AL072_RS04760	COG2329	Antibiotic biosynthesis monooxygenase
AL072_RS04765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL072_RS04770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL072_RS04775	COG1396	sequence-specific DNA binding
AL072_RS04780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL072_RS04785	COG1253	flavin adenine dinucleotide binding
AL072_RS04795	COG1702	phosphate starvation-inducible protein PhoH
AL072_RS04800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL072_RS04810	COG2967	ApaG domain
AL072_RS04815	COG0302	gtp cyclohydrolase
AL072_RS04820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL072_RS04830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL072_RS04835	COG0668	transmembrane transport
AL072_RS04850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL072_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL072_RS04870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL072_RS04885	COG0730	response to heat
AL072_RS04900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL072_RS04920	COG1420	regulation of RNA biosynthetic process
AL072_RS04930	COG0606	chelatase, subunit chli
AL072_RS04960	COG0180	Tryptophanyl-tRNA synthetase
AL072_RS04975	COG0189	ligase activity
AL072_RS04985	COG0792	nuclease activity
AL072_RS04990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL072_RS05025	COG4133	protoheme IX ABC transporter activity
AL072_RS05030	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL072_RS05035	COG0386	Belongs to the glutathione peroxidase family
AL072_RS05050	COG0739	heme binding
AL072_RS05090	COG0488	(ABC) transporter
AL072_RS05100	COG2205	protein histidine kinase activity
AL072_RS05115	COG0785	Cytochrome C biogenesis protein
AL072_RS05115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL072_RS05120	COG1846	Transcriptional regulator
AL072_RS05135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL072_RS05165	COG1074	ATP-dependent DNA helicase activity
AL072_RS05170	COG2887	Belongs to the helicase family. UvrD subfamily
AL072_RS05175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL072_RS05185	COG0802	atpase or kinase
AL072_RS05210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL072_RS05220	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL072_RS05240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL072_RS05315	COG3585	molybdate ion transport
AL072_RS05320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL072_RS05325	COG0840	transmembrane signaling receptor activity
AL072_RS05335	COG0783	Belongs to the Dps family
AL072_RS05345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AL072_RS05370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL072_RS05385	COG0776	regulation of translation
AL072_RS05395	COG2423	ornithine cyclodeaminase activity
AL072_RS05400	COG3920	Histidine kinase
AL072_RS05430	COG0137	argininosuccinate synthase activity
AL072_RS05455	COG1272	protein, Hemolysin III
AL072_RS05470	COG0583	DNA-binding transcription factor activity
AL072_RS05475	COG0477	Major facilitator Superfamily
AL072_RS05480	COG1024	Enoyl-CoA hydratase
AL072_RS05490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL072_RS05490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL072_RS05500	COG0138	bifunctional purine biosynthesis protein purh
AL072_RS05520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL072_RS05525	COG0583	DNA-binding transcription factor activity
AL072_RS05540	COG0861	Integral membrane protein TerC family
AL072_RS05545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL072_RS05555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL072_RS05590	COG0840	transmembrane signaling receptor activity
AL072_RS05595	COG5265	(ABC) transporter
AL072_RS05610	COG0135	phosphoribosylanthranilate isomerase activity
AL072_RS05620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL072_RS05630	COG0156	8-amino-7-oxononanoate synthase activity
AL072_RS05650	COG1177	transmembrane transport
AL072_RS05670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL072_RS05680	COG3278	Belongs to the heme-copper respiratory oxidase family
AL072_RS05710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL072_RS05715	COG1612	heme a metabolic process
AL072_RS05720	COG3772	lysozyme
AL072_RS05730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL072_RS05735	COG0459	protein refolding
AL072_RS05750	COG4566	intracellular signal transduction
AL072_RS05770	COG0583	DNA-binding transcription factor activity
AL072_RS05805	COG0444	Belongs to the ABC transporter superfamily
AL072_RS05810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL072_RS05815	COG0601	transmembrane transport
AL072_RS05820	COG0492	ferredoxin-NADP+ reductase activity
AL072_RS05830	COG1695	Transcriptional regulator
AL072_RS05845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL072_RS05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL072_RS05870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL072_RS05875	COG1595	DNA-templated transcription, initiation
AL072_RS05900	COG2205	protein histidine kinase activity
AL072_RS05900	COG2202	Pas domain
AL072_RS05930	COG2358	TRAP transporter, solute receptor (TAXI family
AL072_RS05950	COG0825	malonyl-CoA metabolic process
AL072_RS05960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL072_RS05965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL072_RS05970	COG1842	Phage shock protein A
AL072_RS05990	COG1442	glycosyl transferase family 8
AL072_RS05990	COG1216	Glycosyl transferase, family 2
AL072_RS06020	COG0181	hydroxymethylbilane synthase activity
AL072_RS06025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL072_RS06035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL072_RS06050	COG0587	DNA-directed DNA polymerase activity
AL072_RS06065	COG0784	Response regulator, receiver
AL072_RS06065	COG3437	response regulator, receiver
AL072_RS06070	COG3158	transport of potassium into the cell
AL072_RS06075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL072_RS06090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL072_RS06095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL072_RS06100	COG0842	Transport permease protein
AL072_RS06105	COG2137	regulation of response to DNA damage stimulus
AL072_RS06110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL072_RS06120	COG1703	isobutyryl-CoA mutase activity
AL072_RS06125	COG4172	Belongs to the ABC transporter superfamily
AL072_RS06130	COG4239	(ABC) transporter, permease
AL072_RS06135	COG4174	ABC transporter (Permease)
AL072_RS06140	COG4166	transmembrane transport
AL072_RS06145	COG4166	transmembrane transport
AL072_RS06180	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL072_RS06185	COG3474	cytochrome
AL072_RS06195	COG2201	protein-glutamate methylesterase activity
AL072_RS06200	COG2766	serine protein kinase
AL072_RS06205	COG2718	Belongs to the UPF0229 family
AL072_RS06210	COG2719	SpoVR family
AL072_RS06215	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL072_RS06230	COG0318	PFAM AMP-dependent synthetase and ligase
AL072_RS06235	COG1254	Belongs to the acylphosphatase family
AL072_RS06265	COG2022	thiamine diphosphate biosynthetic process
AL072_RS06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL072_RS06275	COG2022	thiamine diphosphate biosynthetic process
AL072_RS06400	COG3119	arylsulfatase activity
AL072_RS06410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL072_RS06415	COG4974	Belongs to the 'phage' integrase family
AL072_RS06425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL072_RS06445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL072_RS06455	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL072_RS06480	COG0513	Belongs to the DEAD box helicase family
AL072_RS06485	COG2032	superoxide dismutase activity
AL072_RS06550	COG0167	dihydroorotate dehydrogenase activity
AL072_RS06570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL072_RS06575	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL072_RS06590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL072_RS06605	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL072_RS06615	COG0840	transmembrane signaling receptor activity
AL072_RS06620	COG2871	sodium ion transport
AL072_RS06630	COG3327	negative regulation of DNA-templated transcription, initiation
AL072_RS06660	COG0625	glutathione transferase activity
AL072_RS06685	COG1278	Cold shock
AL072_RS06705	COG0586	Pfam SNARE associated Golgi protein
AL072_RS06715	COG2885	chlorophyll binding
AL072_RS06730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL072_RS06740	COG2205	protein histidine kinase activity
AL072_RS06750	COG2350	Protein conserved in bacteria
AL072_RS06770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL072_RS06780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL072_RS06795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL072_RS06810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL072_RS06820	COG3279	Response regulator of the LytR AlgR family
AL072_RS06835	COG2205	protein histidine kinase activity
AL072_RS06835	COG0784	Response regulator, receiver
AL072_RS06835	COG5002	protein histidine kinase activity
AL072_RS06840	COG2203	Gaf domain
AL072_RS06840	COG3706	GGDEF domain
AL072_RS06840	COG4251	negative regulation of phosphorylation
AL072_RS06840	COG5001	Diguanylate cyclase
AL072_RS06855	COG1595	DNA-templated transcription, initiation
AL072_RS06870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL072_RS06875	COG2084	Dehydrogenase
AL072_RS06885	COG0679	Auxin Efflux Carrier
AL072_RS06895	COG2972	Histidine kinase
AL072_RS06895	COG0840	transmembrane signaling receptor activity
AL072_RS06900	COG1199	ATP-dependent helicase activity
AL072_RS06900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL072_RS06905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL072_RS06915	COG0513	Belongs to the DEAD box helicase family
AL072_RS06930	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL072_RS06935	COG0242	peptide deformylase activity
AL072_RS06940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL072_RS06945	COG0101	tRNA pseudouridine synthase activity
AL072_RS06955	COG0583	DNA-binding transcription factor activity
AL072_RS06965	COG0747	negative chemotaxis
AL072_RS06970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL072_RS06980	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL072_RS06985	COG0277	FAD linked oxidase domain protein
AL072_RS06990	COG0009	L-threonylcarbamoyladenylate synthase
AL072_RS06995	COG1192	Involved in chromosome partitioning
AL072_RS07005	COG2193	ferroxidase activity
AL072_RS07020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL072_RS07025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL072_RS07035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL072_RS07050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL072_RS07060	COG1902	pentaerythritol trinitrate reductase activity
AL072_RS07065	COG1278	Cold shock
AL072_RS07105	COG0436	Aminotransferase
AL072_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS07125	COG1322	Protein conserved in bacteria
AL072_RS07130	COG0840	transmembrane signaling receptor activity
AL072_RS07130	COG0840	transmembrane signaling receptor activity
AL072_RS07150	COG0071	Belongs to the small heat shock protein (HSP20) family
AL072_RS07155	COG0579	oxidoreductase
AL072_RS07160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL072_RS07180	COG1366	Belongs to the anti-sigma-factor antagonist family
AL072_RS07185	COG0840	transmembrane signaling receptor activity
AL072_RS07190	COG2201	protein-glutamate methylesterase activity
AL072_RS07195	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL072_RS07205	COG0840	transmembrane signaling receptor activity
AL072_RS07210	COG0835	chemotaxis
AL072_RS07215	COG2198	Histidine kinase
AL072_RS07215	COG0643	Histidine kinase
AL072_RS07220	COG0745	RESPONSE REGULATOR receiver
AL072_RS07230	COG1051	belongs to the nudix hydrolase family
AL072_RS07245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL072_RS07250	COG0799	negative regulation of ribosome biogenesis
AL072_RS07255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL072_RS07260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL072_RS07265	COG4942	peptidase
AL072_RS07270	COG0793	Belongs to the peptidase S41A family
AL072_RS07280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL072_RS07290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL072_RS07295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL072_RS07300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL072_RS07315	COG0071	Belongs to the small heat shock protein (HSP20) family
AL072_RS07325	COG0254	rRNA binding
AL072_RS07330	COG1132	(ABC) transporter
AL072_RS07335	COG0842	Transport permease protein
AL072_RS07340	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AL072_RS07375	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL072_RS07380	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL072_RS07385	COG0183	Belongs to the thiolase family
AL072_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS07395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL072_RS07405	COG2835	tetraacyldisaccharide 4'-kinase activity
AL072_RS07415	COG3118	belongs to the thioredoxin family
AL072_RS07430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL072_RS07455	COG0463	Glycosyl transferase, family 2
AL072_RS07465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL072_RS07495	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL072_RS07505	COG1846	Transcriptional regulator
AL072_RS07525	COG0312	modulator of DNA gyrase
AL072_RS07530	COG0004	ammonium transporteR
AL072_RS07535	COG0047	phosphoribosylformylglycinamidine synthase activity
AL072_RS07540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL072_RS07570	COG0751	glycine-tRNA ligase activity
AL072_RS07575	COG0752	glycyl-tRNA synthetase alpha subunit
AL072_RS07620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL072_RS07630	COG3852	Histidine kinase
AL072_RS07635	COG4191	Histidine kinase
AL072_RS07640	COG5002	protein histidine kinase activity
AL072_RS07650	COG2176	DNA-directed DNA polymerase activity
AL072_RS07650	COG5002	protein histidine kinase activity
AL072_RS07655	COG0745	RESPONSE REGULATOR receiver
AL072_RS07665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL072_RS07670	COG2917	probably involved in intracellular septation
AL072_RS07685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL072_RS07710	COG5554	nitrogen fixation
AL072_RS07725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL072_RS07755	COG1131	(ABC) transporter
AL072_RS07770	COG0784	Response regulator, receiver
AL072_RS07770	COG4191	Histidine kinase
AL072_RS07800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL072_RS07835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL072_RS07840	COG1346	cytolysis
AL072_RS07845	COG1380	Effector of murein hydrolase LrgA
AL072_RS07860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL072_RS07865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL072_RS07870	COG0793	Belongs to the peptidase S41A family
AL072_RS07875	COG0557	exoribonuclease II activity
AL072_RS07885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL072_RS07920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL072_RS07940	COG0717	Belongs to the dCTP deaminase family
AL072_RS07945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL072_RS07960	COG0693	protein deglycase activity
AL072_RS07965	COG2197	response regulator
AL072_RS07970	COG2197	response regulator
AL072_RS07975	COG0829	nickel cation binding
AL072_RS07980	COG0831	urea catabolic process
AL072_RS07985	COG0832	Belongs to the urease beta subunit family
AL072_RS07990	COG0804	urea catabolic process
AL072_RS07995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL072_RS08000	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AL072_RS08005	COG0830	nickel cation binding
AL072_RS08010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL072_RS08025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL072_RS08040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL072_RS08045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL072_RS08050	COG0028	Belongs to the TPP enzyme family
AL072_RS08065	COG0768	penicillin binding
AL072_RS08085	COG2862	Uncharacterized protein family, UPF0114
AL072_RS08095	COG0140	phosphoribosyl-ATP diphosphatase activity
AL072_RS08100	COG0500	methyltransferase
AL072_RS08190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL072_RS08195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL072_RS08200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL072_RS08205	COG0649	NAD binding
AL072_RS08210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL072_RS08220	COG1034	ATP synthesis coupled electron transport
AL072_RS08225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL072_RS08240	COG0713	ATP synthesis coupled electron transport
AL072_RS08255	COG1007	ATP synthesis coupled electron transport
AL072_RS08275	COG0346	lactoylglutathione lyase activity
AL072_RS08285	COG0519	Catalyzes the synthesis of GMP from XMP
AL072_RS08300	COG0442	prolyl-tRNA aminoacylation
AL072_RS08310	COG1136	(ABC) transporter
AL072_RS08320	COG1335	isochorismatase
AL072_RS08325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL072_RS08330	COG0564	pseudouridine synthase activity
AL072_RS08335	COG0546	phosphoglycolate phosphatase activity
AL072_RS08350	COG0354	folic acid binding
AL072_RS08355	COG3845	ABC transporter
AL072_RS08360	COG4603	Belongs to the binding-protein-dependent transport system permease family
AL072_RS08425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL072_RS08430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL072_RS08440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL072_RS08445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL072_RS08455	COG0248	Ppx GppA phosphatase
AL072_RS08475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL072_RS08490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL072_RS08495	COG0849	cell division
AL072_RS08500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL072_RS08505	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL072_RS08510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL072_RS08515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL072_RS08525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL072_RS08535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL072_RS08550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL072_RS08570	COG2001	Belongs to the MraZ family
AL072_RS08580	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL072_RS08590	COG0488	(ABC) transporter
AL072_RS08615	COG3284	Transcriptional regulator
AL072_RS08620	COG3706	GGDEF domain
AL072_RS08655	COG3436	PFAM IS66 Orf2 family protein
AL072_RS08660	COG4372	Transposase
AL072_RS08690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL072_RS08725	COG3328	transposase activity
AL072_RS08770	COG0482	sulfurtransferase activity
AL072_RS08780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL072_RS08785	COG1104	cysteine desulfurase activity
AL072_RS08800	COG2945	thiolester hydrolase activity
AL072_RS08835	COG0583	DNA-binding transcription factor activity
AL072_RS08845	COG3300	MHYT domain
AL072_RS08845	COG5001	Diguanylate cyclase
AL072_RS08855	COG0193	aminoacyl-tRNA hydrolase activity
AL072_RS08860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL072_RS08870	COG0124	histidyl-tRNA synthetase
AL072_RS08880	COG0418	dihydroorotase activity
AL072_RS08885	COG0859	PFAM glycosyl transferase family 9
AL072_RS08885	COG0457	Tetratricopeptide repeat
AL072_RS08890	COG1570	exodeoxyribonuclease VII activity
AL072_RS08905	COG0590	tRNA wobble adenosine to inosine editing
AL072_RS08910	COG1187	pseudouridine synthase activity
AL072_RS08915	COG0742	ribosomal rna small subunit methyltransferase
AL072_RS08940	COG2910	NAD(P)H-binding
AL072_RS08955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL072_RS08985	COG2197	response regulator
AL072_RS08990	COG2197	response regulator
AL072_RS08995	COG0210	DNA helicase
AL072_RS09005	COG2264	protein methyltransferase activity
AL072_RS09015	COG0006	proline dipeptidase activity
AL072_RS09040	COG0612	Peptidase, M16
AL072_RS09045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL072_RS09065	COG0483	inositol monophosphate 1-phosphatase activity
AL072_RS09070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL072_RS09085	COG0730	response to heat
AL072_RS09090	COG0352	thiamine-phosphate diphosphorylase activity
AL072_RS09095	COG1830	Aldolase
AL072_RS09145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL072_RS09150	COG1692	metallophosphoesterase
AL072_RS09155	COG0217	transcriptional regulatory protein
AL072_RS09165	COG0632	four-way junction helicase activity
AL072_RS09170	COG2255	four-way junction helicase activity
AL072_RS09175	COG0824	Thioesterase
AL072_RS09185	COG0848	biopolymer transport protein
AL072_RS09200	COG2885	chlorophyll binding
AL072_RS09210	COG0037	tRNA processing
AL072_RS09215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL072_RS09225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL072_RS09230	COG1295	ribonuclease BN
AL072_RS09235	COG3152	Membrane
AL072_RS09245	COG4520	surface antigen
AL072_RS09250	COG0259	pyridoxamine-phosphate oxidase activity
AL072_RS09260	COG0840	transmembrane signaling receptor activity
AL072_RS09270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL072_RS09275	COG2770	Histidine kinase
AL072_RS09275	COG3437	response regulator, receiver
AL072_RS09280	COG0409	Hydrogenase expression formation protein
AL072_RS09310	COG3685	Protein conserved in bacteria
AL072_RS09325	COG4957	zinc ion binding
AL072_RS09330	COG0698	ribose 5-phosphate isomerase
AL072_RS09335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL072_RS09340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL072_RS09345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AL072_RS09360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL072_RS09370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL072_RS09370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL072_RS09380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL072_RS09380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL072_RS09400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL072_RS09405	COG0416	fatty acid biosynthetic process
AL072_RS09510	COG2273	Hydrolase Family 16
AL072_RS09510	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL072_RS09540	COG0582	viral genome integration into host DNA
AL072_RS09580	COG0582	viral genome integration into host DNA
AL072_RS09730	COG3772	lysozyme
AL072_RS09740	COG1764	response to oxidative stress
AL072_RS09745	COG1846	Transcriptional regulator
AL072_RS09750	COG0456	acetyltransferase
AL072_RS09760	COG2890	protein-(glutamine-N5) methyltransferase activity
AL072_RS09765	COG1393	Belongs to the ArsC family
AL072_RS09770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL072_RS09780	COG1403	HNH endonuclease
AL072_RS09800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL072_RS09845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL072_RS09880	COG3108	Peptidase M15
AL072_RS09885	COG1396	sequence-specific DNA binding
AL072_RS09905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL072_RS09910	COG0511	ligase activity, forming carbon-carbon bonds
AL072_RS09915	COG0439	Biotin carboxylase
AL072_RS09925	COG0840	transmembrane signaling receptor activity
AL072_RS09935	COG0745	RESPONSE REGULATOR receiver
AL072_RS09955	COG0432	Pfam Uncharacterised protein family UPF0047
AL072_RS09965	COG0745	RESPONSE REGULATOR receiver
AL072_RS09970	COG2205	protein histidine kinase activity
AL072_RS09975	COG0628	permease
AL072_RS09985	COG0616	signal peptide processing
AL072_RS09995	COG0745	RESPONSE REGULATOR receiver
AL072_RS10005	COG0436	Aminotransferase
AL072_RS10015	COG1494	fructose-1,6-bisphosphatase
AL072_RS10025	COG2205	protein histidine kinase activity
AL072_RS10035	COG1324	tolerance protein
AL072_RS10040	COG0303	'Molybdopterin
AL072_RS10045	COG0583	DNA-binding transcription factor activity
AL072_RS10060	COG2373	Large extracellular alpha-helical protein
AL072_RS10065	COG4953	penicillin-binding protein 1C
AL072_RS10075	COG2132	Multicopper oxidase
AL072_RS10085	COG1914	H( )-stimulated, divalent metal cation uptake system
AL072_RS10135	COG0604	alcohol dehydrogenase
AL072_RS10145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL072_RS10145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL072_RS10155	COG0583	DNA-binding transcription factor activity
AL072_RS10160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL072_RS10165	COG3800	Transcriptional regulator
AL072_RS10165	COG1396	sequence-specific DNA binding
AL072_RS10200	COG0747	negative chemotaxis
AL072_RS10205	COG0601	transmembrane transport
AL072_RS10210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL072_RS10215	COG0444	Belongs to the ABC transporter superfamily
AL072_RS10220	COG1124	(ABC) transporter
AL072_RS10235	COG0583	DNA-binding transcription factor activity
AL072_RS10240	COG0519	Catalyzes the synthesis of GMP from XMP
AL072_RS10240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL072_RS10245	COG1247	-acetyltransferase
AL072_RS10255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL072_RS10270	COG1758	RNA polymerase activity
AL072_RS10280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL072_RS10285	COG0736	holo-[acyl-carrier-protein] synthase activity
AL072_RS10290	COG0681	Belongs to the peptidase S26 family
AL072_RS10295	COG0571	ribonuclease III activity
AL072_RS10300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL072_RS10315	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AL072_RS10325	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL072_RS10340	COG1360	Flagellar Motor Protein
AL072_RS10350	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL072_RS10360	COG1338	Plays a role in the flagellum-specific transport system
AL072_RS10375	COG2257	FlhB HrpN YscU SpaS Family
AL072_RS10380	COG1815	bacterial-type flagellum-dependent cell motility
AL072_RS10385	COG1558	bacterial-type flagellum-dependent cell motility
AL072_RS10390	COG1677	Flagellar hook-basal body complex protein FliE
AL072_RS10395	COG1987	bacterial-type flagellum assembly
AL072_RS10405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL072_RS10445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL072_RS10455	COG2076	Multidrug Resistance protein
AL072_RS10475	COG0312	modulator of DNA gyrase
AL072_RS10500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL072_RS10510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL072_RS10565	COG1032	radical SAM domain protein
AL072_RS10580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL072_RS10590	COG4786	Flagellar basal body rod
AL072_RS10595	COG4786	Flagellar basal body rod
AL072_RS10620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL072_RS10625	COG1381	Involved in DNA repair and RecF pathway recombination
AL072_RS10655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL072_RS10660	COG0321	lipoyl(octanoyl) transferase activity
AL072_RS10660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL072_RS10665	COG0084	hydrolase, TatD family'
AL072_RS10670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL072_RS10675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL072_RS10680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL072_RS10685	COG1686	Belongs to the peptidase S11 family
AL072_RS10705	COG4774	siderophore transport
AL072_RS10730	COG3932	Exopolysaccharide synthesis, ExoD
AL072_RS10735	COG0488	(ABC) transporter
AL072_RS10740	COG0105	UTP biosynthetic process
AL072_RS10755	COG0745	RESPONSE REGULATOR receiver
AL072_RS10780	COG2815	serine threonine protein kinase
AL072_RS10780	COG0515	serine threonine protein kinase
AL072_RS10805	COG0500	methyltransferase
AL072_RS10925	COG2770	Histidine kinase
AL072_RS10925	COG2208	phosphoserine phosphatase activity
AL072_RS10930	COG1366	Belongs to the anti-sigma-factor antagonist family
AL072_RS10965	COG4191	Histidine kinase
AL072_RS10975	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AL072_RS11015	COG2951	lytic endotransglycosylase activity
AL072_RS11040	COG0114	fumarate hydratase activity
AL072_RS11060	COG5001	Diguanylate cyclase
AL072_RS11065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL072_RS11070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL072_RS11085	COG0205	6-phosphofructokinase activity
AL072_RS11110	COG0288	reversible hydration of carbon dioxide
AL072_RS11125	COG0604	alcohol dehydrogenase
AL072_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS11125	COG3321	synthase
AL072_RS11185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL072_RS11190	COG0840	transmembrane signaling receptor activity
AL072_RS11200	COG2197	response regulator
AL072_RS11215	COG1160	GTP binding
AL072_RS11230	COG0024	Methionine aminopeptidase
AL072_RS11245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL072_RS11250	COG4221	oxidoreductase activity
AL072_RS11260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL072_RS11290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL072_RS11310	COG2814	Major facilitator Superfamily
AL072_RS11330	COG3706	GGDEF domain
AL072_RS11340	COG0473	3-isopropylmalate dehydrogenase activity
AL072_RS11365	COG0330	HflC and HflK could
AL072_RS11375	COG0538	isocitrate dehydrogenase activity
AL072_RS11380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL072_RS11385	COG0359	binds to the 23S rRNA
AL072_RS11395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL072_RS11400	COG0360	Binds together with S18 to 16S ribosomal RNA
AL072_RS11425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL072_RS11430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL072_RS11445	COG1733	regulation of RNA biosynthetic process
AL072_RS11455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL072_RS11485	COG0140	phosphoribosyl-ATP diphosphatase activity
AL072_RS11495	COG0784	Response regulator, receiver
AL072_RS11495	COG3437	response regulator, receiver
AL072_RS11525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL072_RS11530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL072_RS11540	COG1607	acyl-coa hydrolase
AL072_RS11545	COG0187	DNA topoisomerase II activity
AL072_RS11565	COG0513	Belongs to the DEAD box helicase family
AL072_RS11600	COG1561	YicC-like family, N-terminal region
AL072_RS11605	COG4221	oxidoreductase activity
AL072_RS11615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL072_RS11620	COG0303	'Molybdopterin
AL072_RS11625	COG0315	cyclic pyranopterin monophosphate synthase activity
AL072_RS11675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL072_RS11680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL072_RS11685	COG2813	Specifically methylates the guanine in position
AL072_RS11690	COG0667	Aldo Keto reductase
AL072_RS11705	COG1881	PFAM PEBP family protein
AL072_RS11710	COG0113	porphobilinogen synthase activity
AL072_RS11715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL072_RS11720	COG1597	lipid kinase activity
AL072_RS11725	COG1024	Enoyl-CoA hydratase
AL072_RS11730	COG1846	Transcriptional regulator
AL072_RS11745	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL072_RS11760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL072_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS11795	COG0456	acetyltransferase
AL072_RS11800	COG0058	SHG alpha-glucan phosphorylase activity
AL072_RS11805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL072_RS11815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL072_RS11825	COG0745	RESPONSE REGULATOR receiver
AL072_RS11835	COG2307	Protein conserved in bacteria
AL072_RS11835	COG2308	Evidence 4 Homologs of previously reported genes of
AL072_RS11895	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL072_RS11910	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL072_RS11915	COG2814	Major facilitator Superfamily
AL072_RS11920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL072_RS11930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL072_RS11945	COG1862	Preprotein translocase
AL072_RS11950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL072_RS11960	COG3737	Protein of unknown function (DUF498/DUF598)
AL072_RS11965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL072_RS11970	COG1233	COG1233 Phytoene dehydrogenase and related
AL072_RS11975	COG1562	ergosterol biosynthetic process
AL072_RS11980	COG1562	ergosterol biosynthetic process
AL072_RS12000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL072_RS12015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL072_RS12020	COG0248	Ppx GppA phosphatase
AL072_RS12025	COG2801	Transposase and inactivated derivatives
AL072_RS12030	COG0617	tRNA 3'-terminal CCA addition
AL072_RS12045	COG0714	Associated with various cellular activities
AL072_RS12075	COG2323	membrane
AL072_RS12090	COG2226	methyltransferase
AL072_RS12095	COG2814	Major facilitator Superfamily
AL072_RS12100	COG0583	DNA-binding transcription factor activity
AL072_RS12105	COG0629	single-stranded DNA binding
AL072_RS12110	COG2204	response regulator
AL072_RS12135	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL072_RS12140	COG1116	anion transmembrane transporter activity
AL072_RS12145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL072_RS12150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL072_RS12160	COG0483	inositol monophosphate 1-phosphatase activity
AL072_RS12175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL072_RS12180	COG1923	regulation of RNA biosynthetic process
AL072_RS12190	COG3744	PilT protein domain protein
AL072_RS12200	COG2204	response regulator
AL072_RS12230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL072_RS12230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL072_RS12240	COG1942	4-Oxalocrotonate Tautomerase
AL072_RS12245	COG2867	negative regulation of translational initiation
AL072_RS12250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL072_RS12260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL072_RS12270	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL072_RS12275	COG0022	dehydrogenase e1 component
AL072_RS12275	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL072_RS12280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL072_RS12300	COG4149	molybdate abc transporter
AL072_RS12305	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL072_RS12315	COG2261	transglycosylase associated protein
AL072_RS12330	COG2135	peptidase activity
AL072_RS12340	COG2203	Gaf domain
AL072_RS12340	COG2200	EAL domain
AL072_RS12340	COG2199	diguanylate cyclase activity
AL072_RS12350	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL072_RS12355	COG2833	Protein of unknown function (DUF455)
AL072_RS12360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL072_RS12365	COG0328	RNA-DNA hybrid ribonuclease activity
AL072_RS12370	COG0678	peroxiredoxin activity
AL072_RS12375	COG2824	Alkylphosphonate utilization operon protein PhnA
AL072_RS12380	COG4232	protein-disulfide reductase activity
AL072_RS12385	COG1678	Uncharacterized ACR, COG1678
AL072_RS12390	COG0314	molybdopterin synthase activity
AL072_RS12395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL072_RS12405	COG0546	phosphoglycolate phosphatase activity
AL072_RS12410	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL072_RS12415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL072_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS12455	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL072_RS12470	COG0672	)-iron permease
AL072_RS12495	COG0583	DNA-binding transcription factor activity
AL072_RS12500	COG0540	Belongs to the ATCase OTCase family
AL072_RS12520	COG0693	protein deglycase activity
AL072_RS12525	COG1053	succinate dehydrogenase
AL072_RS12525	COG3976	FMN-binding domain protein
AL072_RS12540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL072_RS12555	COG0776	regulation of translation
AL072_RS12560	COG4957	zinc ion binding
AL072_RS12595	COG0741	lytic transglycosylase activity
AL072_RS12600	COG0556	nucleotide-excision repair
AL072_RS12605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL072_RS12610	COG0658	competence protein
AL072_RS12610	COG2333	competence protein COMEC
AL072_RS12615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL072_RS12640	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL072_RS12650	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL072_RS12655	COG3494	Protein of unknown function (DUF1009)
AL072_RS12680	COG0750	zinc metalloprotease
AL072_RS12685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL072_RS12695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL072_RS12700	COG0233	cytoplasmic translational termination
AL072_RS12705	COG0528	UMP kinase activity
AL072_RS12710	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL072_RS12715	COG0052	Belongs to the universal ribosomal protein uS2 family
AL072_RS12720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL072_RS12745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL072_RS12750	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL072_RS12755	COG0509	glycine decarboxylation via glycine cleavage system
AL072_RS12760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL072_RS12780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL072_RS12785	COG1492	cobalamin metabolic process
AL072_RS12820	COG0534	Mate efflux family protein
AL072_RS12825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL072_RS12830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL072_RS12840	COG3328	transposase activity
AL072_RS12865	COG1136	(ABC) transporter
AL072_RS12865	COG0577	efflux transmembrane transporter activity
AL072_RS12870	COG1136	(ABC) transporter
AL072_RS12885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL072_RS12905	COG0149	triose-phosphate isomerase activity
AL072_RS12915	COG1846	Transcriptional regulator
AL072_RS12925	COG0745	RESPONSE REGULATOR receiver
AL072_RS12935	COG2197	response regulator
AL072_RS12945	COG0330	HflC and HflK could
AL072_RS12950	COG0330	HflC and HflK could
AL072_RS12955	COG0489	protein tyrosine kinase activity
AL072_RS12960	COG0443	Heat shock 70 kDa protein
AL072_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
AL072_RS12990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL072_RS12995	COG2205	protein histidine kinase activity
AL072_RS12995	COG0784	Response regulator, receiver
AL072_RS12995	COG5002	protein histidine kinase activity
AL072_RS13005	COG2208	phosphoserine phosphatase activity
AL072_RS13045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL072_RS13050	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL072_RS13130	COG1216	Glycosyl transferase, family 2
AL072_RS13135	COG1396	sequence-specific DNA binding
AL072_RS13170	COG0124	histidyl-tRNA synthetase
AL072_RS13175	COG1846	Transcriptional regulator
AL072_RS13180	COG0300	oxidoreductase activity
AL072_RS13190	COG0628	permease
AL072_RS13195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL072_RS13205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL072_RS13210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL072_RS13215	COG0525	valine-tRNA ligase activity
AL072_RS13225	COG1538	Outer membrane efflux protein
AL072_RS13235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL072_RS13260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL072_RS13265	COG0494	nUDIX hydrolase
AL072_RS13280	COG2897	thiosulfate sulfurtransferase activity
AL072_RS13285	COG0456	acetyltransferase
AL072_RS13300	COG3713	MltA-interacting MipA family protein
AL072_RS13305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL072_RS13310	COG1126	abc transporter atp-binding protein
AL072_RS13315	COG0765	amino acid transport
AL072_RS13320	COG4597	amino acid ABC transporter
AL072_RS13325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL072_RS13330	COG0626	cystathionine gamma-synthase activity
AL072_RS13350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL072_RS13350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL072_RS13375	COG2308	Evidence 4 Homologs of previously reported genes of
AL072_RS13380	COG1360	Flagellar Motor Protein
AL072_RS13385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL072_RS13405	COG0318	PFAM AMP-dependent synthetase and ligase
AL072_RS13410	COG0789	Transcriptional regulator
AL072_RS13420	COG2086	electron transfer activity
AL072_RS13435	COG2205	protein histidine kinase activity
AL072_RS13440	COG0728	peptidoglycan biosynthetic process
AL072_RS13460	COG1765	OsmC-like protein
AL072_RS13465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL072_RS13480	COG0741	lytic transglycosylase activity
AL072_RS13495	COG2226	methyltransferase
AL072_RS13510	COG1217	gtp-binding protein TYPA
AL072_RS13515	COG1178	ABC-type Fe3 transport system permease component
AL072_RS13535	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL072_RS13540	COG1132	(ABC) transporter
AL072_RS13545	COG3842	ATPase activity
AL072_RS13550	COG1840	ABC-type Fe3 transport system, periplasmic component
AL072_RS13555	COG5001	Diguanylate cyclase
AL072_RS13565	COG1742	UPF0060 membrane protein
AL072_RS13580	COG3237	CsbD-like
AL072_RS13585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL072_RS13590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL072_RS13610	COG1845	cytochrome c oxidase, subunit III
AL072_RS13615	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL072_RS13625	COG0109	protoheme IX farnesyltransferase activity
AL072_RS13630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL072_RS13635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL072_RS13640	COG0758	DNA mediated transformation
AL072_RS13645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL072_RS13650	COG1024	Enoyl-CoA hydratase
AL072_RS13655	COG1832	CoA-binding protein
AL072_RS13670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL072_RS13700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL072_RS13715	COG0784	Response regulator, receiver
AL072_RS13720	COG3447	MASE1 domain protein
AL072_RS13720	COG5001	Diguanylate cyclase
AL072_RS13720	COG5002	protein histidine kinase activity
AL072_RS13740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL072_RS13755	COG1238	metal cluster binding
AL072_RS13760	COG0203	ribosomal protein L17
AL072_RS13775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL072_RS13780	COG0469	pyruvate kinase activity
AL072_RS13790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL072_RS13795	COG0251	oxidation-reduction process
AL072_RS13800	COG3591	Belongs to the peptidase S1B family
AL072_RS13805	COG0551	DNA topoisomerase type I activity
AL072_RS13805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL072_RS13885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL072_RS13885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL072_RS13930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AL072_RS13955	COG0154	amidase activity
AL072_RS13960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL072_RS13975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL072_RS13985	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AL072_RS14010	COG0242	peptide deformylase activity
AL072_RS14015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL072_RS14020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL072_RS14025	COG1201	RNA secondary structure unwinding
AL072_RS14040	COG0415	Belongs to the DNA photolyase family
AL072_RS14045	COG0735	belongs to the Fur family
AL072_RS14085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL072_RS14210	COG0488	(ABC) transporter
AL072_RS14595	COG0850	regulation of cytokinetic process
AL072_RS14815	COG2205	protein histidine kinase activity
AL072_RS14830	COG2205	protein histidine kinase activity
AL072_RS15150	COG0628	permease
AL072_RS15220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL072_RS15220	COG2205	protein histidine kinase activity
AL072_RS15695	COG0277	FAD linked oxidase domain protein
AL072_RS16130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL072_RS16460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL072_RS16555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL072_RS16565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL072_RS17250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL072_RS17300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL072_RS17545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL072_RS17725	COG0501	Belongs to the peptidase M48B family
AL072_RS17920	COG0281	malic enzyme
AL072_RS17920	COG0280	phosphate acetyltransferase
AL072_RS17930	COG0280	phosphate acetyltransferase
AL072_RS17930	COG0281	malic enzyme
AL072_RS17965	COG0445	tRNA wobble uridine modification
AL072_RS18095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL072_RS18210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL072_RS18285	COG0730	response to heat
AL072_RS18330	COG0606	chelatase, subunit chli
AL072_RS18635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL072_RS18905	COG0840	transmembrane signaling receptor activity
AL072_RS18960	COG0156	8-amino-7-oxononanoate synthase activity
AL072_RS19035	COG2217	Heavy metal translocating P-type atpase
AL072_RS19570	COG2070	2-Nitropropane dioxygenase
AL072_RS19915	COG5002	protein histidine kinase activity
AL072_RS19915	COG0784	Response regulator, receiver
AL072_RS20115	COG0612	Peptidase, M16
AL072_RS20390	COG5002	protein histidine kinase activity
AL072_RS20390	COG2205	protein histidine kinase activity
AL072_RS20390	COG0784	Response regulator, receiver
AL072_RS20400	COG0784	Response regulator, receiver
AL072_RS20400	COG3437	response regulator, receiver
AL072_RS20680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL072_RS20700	COG0085	RNA polymerase activity
AL072_RS20875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL072_RS20880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL072_RS20900	COG1530	ribonuclease E activity
AL072_RS21230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL072_RS22390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL072_RS22780	COG1473	amidohydrolase
AL072_RS23385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL072_RS24330	COG0085	RNA polymerase activity
AL072_RS24465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL072_RS24465	COG0561	phosphatase activity
AL072_RS24810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL072_RS24940	COG0024	Methionine aminopeptidase
AL072_RS25105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL072_RS25105	COG0574	Belongs to the PEP-utilizing enzyme family
AL072_RS25110	COG0574	Belongs to the PEP-utilizing enzyme family
AL072_RS25110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL072_RS25135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL072_RS25530	COG2205	protein histidine kinase activity
AL072_RS25790	COG1960	acyl-CoA dehydrogenase activity
AL072_RS26025	COG2205	protein histidine kinase activity
AL072_RS26295	COG0646	methionine synthase
AL072_RS26295	COG1410	methionine synthase
AL072_RS26365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL072_RS26380	COG0596	Alpha beta hydrolase
AL072_RS26380	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL072_RS26680	COG2894	cell division
AL072_RS26810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL072_RS26905	COG0612	Peptidase, M16
AL072_RS26940	COG2030	dehydratase
AL072_RS26985	COG1686	Belongs to the peptidase S11 family
AL072_RS27130	COG2205	protein histidine kinase activity
AL072_RS27130	COG2198	Histidine kinase
AL072_RS27130	COG0784	Response regulator, receiver
AL072_RS27300	COG0438	transferase activity, transferring glycosyl groups
AL072_RS27590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL072_RS27980	COG0126	phosphoglycerate kinase activity
AL072_RS28470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AL072_RS28470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL072_RS28655	COG0646	methionine synthase
AL072_RS28655	COG1410	methionine synthase
AL072_RS28675	COG2853	Lipoprotein
AL072_RS28715	COG3199	ATP-NAD kinase
AL072_RS28820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL072_RS28900	COG4948	Mandelate Racemase Muconate Lactonizing
AL072_RS28980	COG3383	formate dehydrogenase (NAD+) activity
AL072_RS28980	COG0243	molybdopterin cofactor binding
AL072_RS29100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL072_RS29120	COG0612	Peptidase, M16
AL072_RS29150	COG2205	protein histidine kinase activity
AL072_RS29350	COG3842	ATPase activity
AL072_RS29810	COG0085	RNA polymerase activity
AL072_RS30055	COG1530	ribonuclease E activity
AL072_RS30115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL072_RS30300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL072_RS30315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL072_RS30670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL072_RS30670	COG0574	Belongs to the PEP-utilizing enzyme family
AL072_RS30805	COG2433	Pfam Transposase IS66
AL072_RS31125	COG0243	molybdopterin cofactor binding
AL072_RS31130	COG0243	molybdopterin cofactor binding
AL072_RS31275	COG0252	asparaginase activity
AL072_RS31335	COG0318	PFAM AMP-dependent synthetase and ligase
AL072_RS31390	COG0247	lactate metabolic process
AL072_RS31465	COG0357	Ribosomal RNA small subunit methyltransferase G
AL072_RS31465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL072_RS31600	COG2070	2-Nitropropane dioxygenase
AL072_RS31755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL072_RS32025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL072_RS32070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL072_RS32085	COG2205	protein histidine kinase activity
AL072_RS32270	COG2205	protein histidine kinase activity
AL072_RS32375	COG1519	Transferase
AL072_RS32600	COG0088	Forms part of the polypeptide exit tunnel
AL072_RS32665	COG0085	RNA polymerase activity
AL072_RS33055	COG0596	Alpha beta hydrolase
AL072_RS33055	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL072_RS33070	COG1063	alcohol dehydrogenase