locus-tag	class	description
AVIN_RS00055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVIN_RS00065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVIN_RS00080	COG2837	iron assimilation
AVIN_RS00095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVIN_RS00100	COG0751	glycine-tRNA ligase activity
AVIN_RS00110	COG2818	Glycosylase
AVIN_RS00115	COG1525	nuclease
AVIN_RS00115	COG0737	Belongs to the 5'-nucleotidase family
AVIN_RS00115	COG4085	toxin activity
AVIN_RS00120	COG0569	domain protein
AVIN_RS00125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVIN_RS00135	COG0242	peptide deformylase activity
AVIN_RS00145	COG0758	DNA mediated transformation
AVIN_RS00150	COG0009	L-threonylcarbamoyladenylate synthase
AVIN_RS00160	COG0408	coproporphyrinogen oxidase activity
AVIN_RS00165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVIN_RS00180	COG2132	Multicopper oxidase
AVIN_RS00190	COG1285	pathogenesis
AVIN_RS00235	COG0655	NAD(P)H dehydrogenase (quinone) activity
AVIN_RS00240	COG0700	Nucleoside recognition
AVIN_RS00255	COG3706	GGDEF domain
AVIN_RS00285	COG1126	abc transporter atp-binding protein
AVIN_RS00300	COG0210	DNA helicase
AVIN_RS00310	COG0826	peptidase U32
AVIN_RS00325	COG0842	Transport permease protein
AVIN_RS00330	COG0842	Transport permease protein
AVIN_RS00335	COG1131	(ABC) transporter
AVIN_RS00345	COG1309	transcriptional regulator
AVIN_RS00365	COG0596	Alpha beta hydrolase
AVIN_RS00365	COG2945	thiolester hydrolase activity
AVIN_RS00400	COG0675	Transposase, IS605 OrfB family
AVIN_RS00420	COG1335	isochorismatase
AVIN_RS00435	COG1305	Transglutaminase-like
AVIN_RS00440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AVIN_RS00445	COG0735	belongs to the Fur family
AVIN_RS00450	COG1121	(ABC) transporter
AVIN_RS00455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVIN_RS00495	COG0109	protoheme IX farnesyltransferase activity
AVIN_RS00500	COG1612	heme a metabolic process
AVIN_RS00525	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVIN_RS00530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVIN_RS00545	COG0659	secondary active sulfate transmembrane transporter activity
AVIN_RS00575	COG3712	iron ion homeostasis
AVIN_RS00585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVIN_RS00610	COG0252	asparaginase activity
AVIN_RS00630	COG1686	Belongs to the peptidase S11 family
AVIN_RS00645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVIN_RS00670	COG2814	Major facilitator Superfamily
AVIN_RS00675	COG0204	Acyl-transferase
AVIN_RS00675	COG0318	PFAM AMP-dependent synthetase and ligase
AVIN_RS00755	COG3411	Ferredoxin
AVIN_RS00855	COG0523	cobalamin synthesis protein
AVIN_RS00865	COG1607	acyl-coa hydrolase
AVIN_RS00875	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVIN_RS00885	COG1764	response to oxidative stress
AVIN_RS00945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVIN_RS00990	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVIN_RS01010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVIN_RS01015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVIN_RS01025	COG0583	DNA-binding transcription factor activity
AVIN_RS01030	COG0439	Biotin carboxylase
AVIN_RS01035	COG5016	pyruvate
AVIN_RS01035	COG0511	ligase activity, forming carbon-carbon bonds
AVIN_RS01040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS01060	COG0133	tryptophan synthase activity
AVIN_RS01065	COG0159	tryptophan synthase activity
AVIN_RS01085	COG0484	heat shock protein binding
AVIN_RS01090	COG0789	Transcriptional regulator
AVIN_RS01095	COG0730	response to heat
AVIN_RS01120	COG1595	DNA-templated transcription, initiation
AVIN_RS01145	COG2356	endonuclease I
AVIN_RS01155	COG3237	CsbD-like
AVIN_RS01165	COG0789	Transcriptional regulator
AVIN_RS01180	COG2982	Protein involved in outer membrane biogenesis
AVIN_RS01190	COG0778	Nitroreductase
AVIN_RS01195	COG1136	(ABC) transporter
AVIN_RS01195	COG0577	efflux transmembrane transporter activity
AVIN_RS01220	COG0366	Alpha amylase catalytic
AVIN_RS01240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVIN_RS01245	COG2841	Protein conserved in bacteria
AVIN_RS01260	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AVIN_RS01265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVIN_RS01315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVIN_RS01360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVIN_RS01365	COG1758	RNA polymerase activity
AVIN_RS01375	COG1561	YicC-like family, N-terminal region
AVIN_RS01380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVIN_RS01390	COG0708	Exodeoxyribonuclease III
AVIN_RS01395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVIN_RS01405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVIN_RS01415	COG0756	dUTP diphosphatase activity
AVIN_RS01420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVIN_RS01425	COG2003	Belongs to the UPF0758 family
AVIN_RS01430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVIN_RS01435	COG2363	Small membrane protein
AVIN_RS01445	COG2022	thiamine diphosphate biosynthetic process
AVIN_RS01450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVIN_RS01455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVIN_RS01470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVIN_RS01470	COG2813	Specifically methylates the guanine in position
AVIN_RS01475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVIN_RS01480	COG1872	DUF167
AVIN_RS01515	COG0540	Belongs to the ATCase OTCase family
AVIN_RS01525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVIN_RS01550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVIN_RS01570	COG3038	cytochrome b561
AVIN_RS01575	COG2353	YceI-like domain
AVIN_RS01585	COG2205	protein histidine kinase activity
AVIN_RS01600	COG0129	dihydroxy-acid dehydratase activity
AVIN_RS01615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVIN_RS01620	COG0842	Transport permease protein
AVIN_RS01625	COG1131	(ABC) transporter
AVIN_RS01630	COG0840	transmembrane signaling receptor activity
AVIN_RS01635	COG0693	protein deglycase activity
AVIN_RS01640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVIN_RS01670	COG0247	lactate metabolic process
AVIN_RS01680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVIN_RS01685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVIN_RS01690	COG0429	hydrolase of the alpha beta-hydrolase fold
AVIN_RS01695	COG0742	ribosomal rna small subunit methyltransferase
AVIN_RS01700	COG0612	Peptidase, M16
AVIN_RS01705	COG0612	Peptidase, M16
AVIN_RS01710	COG0513	Belongs to the DEAD box helicase family
AVIN_RS01715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVIN_RS01730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVIN_RS01735	COG0738	Major facilitator superfamily
AVIN_RS01745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVIN_RS01805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS01810	COG2814	Major facilitator Superfamily
AVIN_RS01815	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS01820	COG0583	DNA-binding transcription factor activity
AVIN_RS01825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVIN_RS01830	COG3383	formate dehydrogenase (NAD+) activity
AVIN_RS01830	COG0243	molybdopterin cofactor binding
AVIN_RS01835	COG0437	4 iron, 4 sulfur cluster binding
AVIN_RS01840	COG2864	formate dehydrogenase
AVIN_RS01855	COG1595	DNA-templated transcription, initiation
AVIN_RS01915	COG0583	DNA-binding transcription factor activity
AVIN_RS01970	COG0346	lactoylglutathione lyase activity
AVIN_RS02000	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AVIN_RS02075	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVIN_RS02090	COG2194	sulfuric ester hydrolase activity
AVIN_RS02120	COG1151	hydroxylamine reductase activity
AVIN_RS02140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AVIN_RS02145	COG1194	a g-specific adenine glycosylase
AVIN_RS02160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVIN_RS02170	COG0131	Imidazoleglycerol-phosphate dehydratase
AVIN_RS02175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVIN_RS02185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVIN_RS02190	COG0107	imidazoleglycerol-phosphate synthase activity
AVIN_RS02195	COG0793	Belongs to the peptidase S41A family
AVIN_RS02200	COG4942	peptidase
AVIN_RS02205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AVIN_RS02220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVIN_RS02225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVIN_RS02235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVIN_RS02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVIN_RS02250	COG3218	ABC-type transport auxiliary lipoprotein component
AVIN_RS02255	COG1127	ABC transporter
AVIN_RS02260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVIN_RS02265	COG3132	Protein of unknown function, DUF480
AVIN_RS02280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVIN_RS02300	COG0306	phosphate transporter
AVIN_RS02315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AVIN_RS02315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVIN_RS02325	COG5002	protein histidine kinase activity
AVIN_RS02325	COG5001	Diguanylate cyclase
AVIN_RS02325	COG3447	MASE1 domain protein
AVIN_RS02360	COG2918	glutathione biosynthetic process
AVIN_RS02370	COG2183	response to ionizing radiation
AVIN_RS02375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AVIN_RS02385	COG0457	Tetratricopeptide repeat
AVIN_RS02415	COG0189	ligase activity
AVIN_RS02420	COG0189	ligase activity
AVIN_RS02420	COG4067	protein conserved in archaea
AVIN_RS02425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AVIN_RS02440	COG1012	belongs to the aldehyde dehydrogenase family
AVIN_RS02445	COG2186	Transcriptional regulator
AVIN_RS02450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVIN_RS02455	COG2271	Major facilitator Superfamily
AVIN_RS02460	COG2721	sulfolactate sulfo-lyase activity
AVIN_RS02465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS02550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVIN_RS02570	COG1011	Hydrolase
AVIN_RS02575	COG0494	nUDIX hydrolase
AVIN_RS02580	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVIN_RS02590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVIN_RS02595	COG2226	methyltransferase
AVIN_RS02610	COG0126	phosphoglycerate kinase activity
AVIN_RS02620	COG4702	Belongs to the UPF0303 family
AVIN_RS02625	COG0673	inositol 2-dehydrogenase activity
AVIN_RS02630	COG1349	DNA-binding transcription factor activity
AVIN_RS02635	COG1451	nucleotide metabolic process
AVIN_RS02645	COG2354	Protein conserved in bacteria
AVIN_RS02660	COG1289	transmembrane transporter activity
AVIN_RS02670	COG0330	HflC and HflK could
AVIN_RS02675	COG0686	Belongs to the AlaDH PNT family
AVIN_RS02680	COG1309	transcriptional regulator
AVIN_RS02690	COG0625	glutathione transferase activity
AVIN_RS02700	COG2814	Major facilitator Superfamily
AVIN_RS02725	COG0204	Acyl-transferase
AVIN_RS02735	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AVIN_RS02775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVIN_RS02780	COG1040	competence protein
AVIN_RS02785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVIN_RS02790	COG0156	8-amino-7-oxononanoate synthase activity
AVIN_RS02795	COG1073	alpha beta
AVIN_RS02795	COG2226	methyltransferase
AVIN_RS02805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVIN_RS02815	COG4589	Belongs to the CDS family
AVIN_RS02820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AVIN_RS02820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AVIN_RS02825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVIN_RS02870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVIN_RS02875	COG0081	regulation of translation
AVIN_RS02880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVIN_RS02885	COG0222	ribosome binding
AVIN_RS02890	COG0085	RNA polymerase activity
AVIN_RS02895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVIN_RS02900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVIN_RS02905	COG0049	tRNA binding
AVIN_RS02920	COG0051	transcription antitermination factor activity, RNA binding
AVIN_RS02925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVIN_RS02930	COG0088	Forms part of the polypeptide exit tunnel
AVIN_RS02935	COG0089	rRNA binding
AVIN_RS02940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVIN_RS02945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVIN_RS02950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVIN_RS02955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVIN_RS02960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVIN_RS02965	COG0255	Belongs to the universal ribosomal protein uL29 family
AVIN_RS02970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVIN_RS02975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVIN_RS02980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVIN_RS02985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVIN_RS02990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVIN_RS02995	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVIN_RS03000	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVIN_RS03005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVIN_RS03010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVIN_RS03015	COG1841	ribosomal large subunit assembly
AVIN_RS03020	COG0200	Binds to the 23S rRNA
AVIN_RS03030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVIN_RS03035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVIN_RS03045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVIN_RS03050	COG0202	RNA polymerase activity
AVIN_RS03055	COG0203	ribosomal protein L17
AVIN_RS03065	COG2814	Major facilitator Superfamily
AVIN_RS03075	COG0583	DNA-binding transcription factor activity
AVIN_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS03090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVIN_RS03095	COG3047	cAMP biosynthetic process
AVIN_RS03100	COG3047	cAMP biosynthetic process
AVIN_RS03115	COG4181	ATPase activity
AVIN_RS03130	COG3118	belongs to the thioredoxin family
AVIN_RS03135	COG2264	protein methyltransferase activity
AVIN_RS03145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVIN_RS03150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVIN_RS03150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVIN_RS03165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVIN_RS03175	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVIN_RS03180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVIN_RS03190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVIN_RS03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVIN_RS03205	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AVIN_RS03215	COG0443	Heat shock 70 kDa protein
AVIN_RS03230	COG0138	bifunctional purine biosynthesis protein purh
AVIN_RS03250	COG2264	protein methyltransferase activity
AVIN_RS03285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS03300	COG0023	Translation Initiation Factor
AVIN_RS03305	COG1166	arginine decarboxylase activity
AVIN_RS03310	COG0534	Mate efflux family protein
AVIN_RS03320	COG0589	response to stress
AVIN_RS03330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AVIN_RS03385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVIN_RS03400	COG1126	abc transporter atp-binding protein
AVIN_RS03405	COG0765	amino acid transport
AVIN_RS03410	COG0765	amino acid transport
AVIN_RS03420	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AVIN_RS03425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVIN_RS03450	COG0560	Phosphoserine phosphatase
AVIN_RS03450	COG3830	Belongs to the UPF0237 family
AVIN_RS03455	COG1063	alcohol dehydrogenase
AVIN_RS03460	COG0688	phosphatidylethanolamine metabolic process
AVIN_RS03470	COG1162	GTPase activity
AVIN_RS03475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AVIN_RS03485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVIN_RS03485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVIN_RS03490	COG0802	atpase or kinase
AVIN_RS03495	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVIN_RS03500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVIN_RS03505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVIN_RS03510	COG1923	regulation of RNA biosynthetic process
AVIN_RS03515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVIN_RS03520	COG0330	HflC and HflK could
AVIN_RS03525	COG0330	HflC and HflK could
AVIN_RS03535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVIN_RS03540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVIN_RS03555	COG0557	exoribonuclease II activity
AVIN_RS03560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVIN_RS03565	COG0360	Binds together with S18 to 16S ribosomal RNA
AVIN_RS03570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVIN_RS03580	COG0359	binds to the 23S rRNA
AVIN_RS03585	COG0305	Participates in initiation and elongation during chromosome replication
AVIN_RS03600	COG2813	Specifically methylates the guanine in position
AVIN_RS03610	COG1946	Acyl-CoA thioesterase
AVIN_RS03615	COG0546	phosphoglycolate phosphatase activity
AVIN_RS03620	COG2321	neutral zinc metallopeptidase
AVIN_RS03635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVIN_RS03640	COG2252	PERMEase
AVIN_RS03645	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVIN_RS03660	COG4206	TonB-dependent receptor
AVIN_RS03665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVIN_RS03670	COG0142	geranyltranstransferase activity
AVIN_RS03675	COG1722	exodeoxyribonuclease VII activity
AVIN_RS03680	COG5001	Diguanylate cyclase
AVIN_RS03680	COG3300	MHYT domain
AVIN_RS03695	COG3228	Belongs to the MtfA family
AVIN_RS03710	COG1454	alcohol dehydrogenase
AVIN_RS03720	COG3284	Transcriptional regulator
AVIN_RS03725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVIN_RS03760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS03765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS03775	COG4771	TonB-dependent receptor
AVIN_RS03785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS03795	COG4771	TonB-dependent receptor
AVIN_RS03830	COG0702	epimerase
AVIN_RS03840	COG1346	cytolysis
AVIN_RS03850	COG0366	Alpha amylase catalytic
AVIN_RS03855	COG0586	Pfam SNARE associated Golgi protein
AVIN_RS03860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVIN_RS03865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVIN_RS03875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVIN_RS03880	COG0768	penicillin binding
AVIN_RS03885	COG0772	Belongs to the SEDS family
AVIN_RS03890	COG2951	lytic endotransglycosylase activity
AVIN_RS03900	COG1686	Belongs to the peptidase S11 family
AVIN_RS03905	COG2921	Belongs to the UPF0250 family
AVIN_RS03910	COG0321	lipoyl(octanoyl) transferase activity
AVIN_RS03915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVIN_RS03920	COG0028	Belongs to the TPP enzyme family
AVIN_RS03925	COG2951	lytic endotransglycosylase activity
AVIN_RS03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVIN_RS03980	COG2814	Major facilitator Superfamily
AVIN_RS04005	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AVIN_RS04025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS04135	COG0495	leucyl-tRNA aminoacylation
AVIN_RS04145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AVIN_RS04150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVIN_RS04160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVIN_RS04165	COG1702	phosphate starvation-inducible protein PhoH
AVIN_RS04175	COG2801	Transposase and inactivated derivatives
AVIN_RS04175	COG3415	Transposase
AVIN_RS04190	COG3254	rhamnose metabolic process
AVIN_RS04210	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS04215	COG2271	Major facilitator Superfamily
AVIN_RS04220	COG4948	Mandelate Racemase Muconate Lactonizing
AVIN_RS04230	COG1012	belongs to the aldehyde dehydrogenase family
AVIN_RS04240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVIN_RS04245	COG0352	thiamine-phosphate diphosphorylase activity
AVIN_RS04250	COG0351	phosphomethylpyrimidine kinase
AVIN_RS04255	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS04260	COG0019	diaminopimelate decarboxylase activity
AVIN_RS04270	COG2814	Major facilitator Superfamily
AVIN_RS04275	COG4264	IucA IucC family
AVIN_RS04285	COG4772	TonB-dependent receptor
AVIN_RS04295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVIN_RS04300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVIN_RS04305	COG0830	nickel cation binding
AVIN_RS04310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AVIN_RS04315	COG0673	inositol 2-dehydrogenase activity
AVIN_RS04325	COG1301	dicarboxylic acid transport
AVIN_RS04330	COG0596	Alpha beta hydrolase
AVIN_RS04335	COG0583	DNA-binding transcription factor activity
AVIN_RS04370	COG3293	Transposase
AVIN_RS04405	COG1021	2,3-dihydroxybenzoate-AMP ligase
AVIN_RS04410	COG1535	isochorismatase
AVIN_RS04410	COG3433	isochorismatase activity
AVIN_RS04430	COG2801	Transposase and inactivated derivatives
AVIN_RS04450	COG0066	3-isopropylmalate dehydratase activity
AVIN_RS04455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVIN_RS04480	COG0804	urea catabolic process
AVIN_RS04485	COG0832	Belongs to the urease beta subunit family
AVIN_RS04490	COG0831	urea catabolic process
AVIN_RS04495	COG0829	nickel cation binding
AVIN_RS04500	COG4303	Ethanolamine ammonia lyase large subunit
AVIN_RS04505	COG4302	ethanolamine ammonia-lyase activity
AVIN_RS04520	COG1522	sequence-specific DNA binding
AVIN_RS04525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVIN_RS04535	COG1643	Atp-dependent helicase
AVIN_RS04545	COG0513	Belongs to the DEAD box helicase family
AVIN_RS04550	COG0493	'glutamate synthase
AVIN_RS04550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVIN_RS04555	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVIN_RS04580	COG1309	transcriptional regulator
AVIN_RS04585	COG2814	Major facilitator Superfamily
AVIN_RS04615	COG0628	permease
AVIN_RS04630	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AVIN_RS04645	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AVIN_RS04650	COG1858	cytochrome C peroxidase
AVIN_RS04665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVIN_RS04680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AVIN_RS04685	COG3052	prosthetic group binding
AVIN_RS04705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVIN_RS04735	COG1368	sulfuric ester hydrolase activity
AVIN_RS04740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVIN_RS04745	COG4774	siderophore transport
AVIN_RS04760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVIN_RS04760	COG4651	solute:proton antiporter activity
AVIN_RS04800	COG0745	RESPONSE REGULATOR receiver
AVIN_RS04805	COG2205	protein histidine kinase activity
AVIN_RS04810	COG0306	phosphate transporter
AVIN_RS04820	COG0848	biopolymer transport protein
AVIN_RS04840	COG0583	DNA-binding transcription factor activity
AVIN_RS04845	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS04850	COG1024	Enoyl-CoA hydratase
AVIN_RS04860	COG1024	Enoyl-CoA hydratase
AVIN_RS04870	COG0583	DNA-binding transcription factor activity
AVIN_RS04875	COG3719	Belongs to the RNase T2 family
AVIN_RS04910	COG3223	Belongs to the PsiE family
AVIN_RS04915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVIN_RS04920	COG3293	Transposase
AVIN_RS05000	COG0628	permease
AVIN_RS05015	COG1294	oxidase, subunit
AVIN_RS05020	COG1271	oxidase subunit
AVIN_RS05025	COG2323	membrane
AVIN_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS05040	COG3685	Protein conserved in bacteria
AVIN_RS05050	COG2204	response regulator
AVIN_RS05070	COG2010	Cytochrome c
AVIN_RS05070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVIN_RS05075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVIN_RS05095	COG3022	response to hydroperoxide
AVIN_RS05105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVIN_RS05110	COG0315	cyclic pyranopterin monophosphate synthase activity
AVIN_RS05115	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AVIN_RS05135	COG3415	Transposase
AVIN_RS05135	COG2801	Transposase and inactivated derivatives
AVIN_RS05145	COG2827	Endonuclease containing a URI domain
AVIN_RS05165	COG0145	ligase activity
AVIN_RS05170	COG4647	ligase activity
AVIN_RS05175	COG0145	ligase activity
AVIN_RS05185	COG0523	cobalamin synthesis protein
AVIN_RS05195	COG3081	Nucleoid-associated protein
AVIN_RS05205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVIN_RS05215	COG0583	DNA-binding transcription factor activity
AVIN_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS05240	COG0420	3'-5' exonuclease activity
AVIN_RS05245	COG0419	ATPase involved in DNA repair
AVIN_RS05255	COG1253	flavin adenine dinucleotide binding
AVIN_RS05265	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AVIN_RS05290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVIN_RS05295	COG0795	lipopolysaccharide-transporting ATPase activity
AVIN_RS05300	COG0795	lipopolysaccharide-transporting ATPase activity
AVIN_RS05310	COG1278	Cold shock
AVIN_RS05325	COG0728	peptidoglycan biosynthetic process
AVIN_RS05330	COG0196	riboflavin kinase activity
AVIN_RS05335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVIN_RS05340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVIN_RS05345	COG1047	Peptidyl-prolyl cis-trans
AVIN_RS05350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVIN_RS05385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVIN_RS05440	COG1132	(ABC) transporter
AVIN_RS05450	COG1252	NADH dehydrogenase
AVIN_RS05475	COG0237	dephospho-CoA kinase activity
AVIN_RS05480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVIN_RS05505	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVIN_RS05515	COG0084	hydrolase, TatD family'
AVIN_RS05535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVIN_RS05535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVIN_RS05540	COG1105	Belongs to the carbohydrate kinase PfkB family
AVIN_RS05545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AVIN_RS05545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVIN_RS05545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AVIN_RS05565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVIN_RS05570	COG2831	hemolysin activation secretion protein
AVIN_RS05585	COG0019	diaminopimelate decarboxylase activity
AVIN_RS05590	COG4774	siderophore transport
AVIN_RS05595	COG3128	pkhd-type hydroxylase
AVIN_RS05630	COG3128	pkhd-type hydroxylase
AVIN_RS05635	COG4774	siderophore transport
AVIN_RS05650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AVIN_RS05655	COG1984	allophanate hydrolase subunit 2
AVIN_RS05660	COG4608	Belongs to the ABC transporter superfamily
AVIN_RS05665	COG0444	Belongs to the ABC transporter superfamily
AVIN_RS05670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVIN_RS05675	COG0601	transmembrane transport
AVIN_RS05680	COG0747	negative chemotaxis
AVIN_RS05695	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVIN_RS05715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVIN_RS05720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVIN_RS05725	COG0154	amidase activity
AVIN_RS05730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVIN_RS05735	COG1077	Cell shape determining protein MreB Mrl
AVIN_RS05740	COG1792	Involved in formation and maintenance of cell shape
AVIN_RS05745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AVIN_RS05750	COG0424	maF-like protein
AVIN_RS05755	COG1530	ribonuclease E activity
AVIN_RS05765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVIN_RS05770	COG0312	modulator of DNA gyrase
AVIN_RS05775	COG3028	Belongs to the UPF0307 family
AVIN_RS05780	COG0312	modulator of DNA gyrase
AVIN_RS05790	COG1660	Displays ATPase and GTPase activities
AVIN_RS05810	COG1137	ATPase activity
AVIN_RS05815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AVIN_RS05825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVIN_RS05835	COG1127	ABC transporter
AVIN_RS05840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVIN_RS05845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVIN_RS05860	COG5007	Belongs to the BolA IbaG family
AVIN_RS05865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVIN_RS05870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVIN_RS05875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVIN_RS05880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVIN_RS05885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVIN_RS05895	COG0175	sulfate reduction
AVIN_RS05920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVIN_RS05925	COG1515	deoxyribonuclease V activity
AVIN_RS05930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVIN_RS05935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVIN_RS05940	COG0723	plastoquinol--plastocyanin reductase activity
AVIN_RS05945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVIN_RS05950	COG2857	Cytochrome c1
AVIN_RS05955	COG0625	glutathione transferase activity
AVIN_RS05960	COG2969	positive regulation of protein catabolic process
AVIN_RS05965	COG2823	Periplasmic or secreted lipoprotein
AVIN_RS05970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AVIN_RS05975	COG0792	nuclease activity
AVIN_RS05990	COG2001	Belongs to the MraZ family
AVIN_RS05995	COG0275	rRNA processing
AVIN_RS06010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVIN_RS06015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVIN_RS06020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVIN_RS06025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVIN_RS06030	COG0772	Belongs to the SEDS family
AVIN_RS06035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVIN_RS06040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVIN_RS06045	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVIN_RS06065	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVIN_RS06075	COG0653	protein targeting
AVIN_RS06090	COG0494	nUDIX hydrolase
AVIN_RS06095	COG2096	Adenosyltransferase
AVIN_RS06110	COG1666	GTP binding
AVIN_RS06125	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS06130	COG0748	coenzyme F420 binding
AVIN_RS06135	COG3030	protein affecting phage T7 exclusion by the F plasmid
AVIN_RS06140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVIN_RS06180	COG1024	Enoyl-CoA hydratase
AVIN_RS06205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVIN_RS06245	COG3086	response to oxidative stress
AVIN_RS06250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVIN_RS06255	COG0481	GTPase activity
AVIN_RS06270	COG0571	ribonuclease III activity
AVIN_RS06275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVIN_RS06285	COG1381	Involved in DNA repair and RecF pathway recombination
AVIN_RS06290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVIN_RS06300	COG0500	methyltransferase
AVIN_RS06305	COG2226	methyltransferase
AVIN_RS06315	COG1414	Transcriptional regulator
AVIN_RS06325	COG1454	alcohol dehydrogenase
AVIN_RS06330	COG2610	gluconate transmembrane transporter activity
AVIN_RS06335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVIN_RS06355	COG0583	DNA-binding transcription factor activity
AVIN_RS06380	COG3842	ATPase activity
AVIN_RS06390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVIN_RS06400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVIN_RS06405	COG0418	dihydroorotase activity
AVIN_RS06410	COG0137	argininosuccinate synthase activity
AVIN_RS06450	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVIN_RS06455	COG0303	'Molybdopterin
AVIN_RS06470	COG0488	(ABC) transporter
AVIN_RS06475	COG0589	response to stress
AVIN_RS06480	COG2814	Major facilitator Superfamily
AVIN_RS06495	COG1024	Enoyl-CoA hydratase
AVIN_RS06500	COG1012	belongs to the aldehyde dehydrogenase family
AVIN_RS06505	COG3320	Male sterility
AVIN_RS06505	COG1022	Amp-dependent synthetase and ligase
AVIN_RS06515	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS06535	COG0745	RESPONSE REGULATOR receiver
AVIN_RS06540	COG2205	protein histidine kinase activity
AVIN_RS06545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVIN_RS06550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVIN_RS06590	COG1024	Enoyl-CoA hydratase
AVIN_RS06590	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS06595	COG0183	Belongs to the thiolase family
AVIN_RS06625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVIN_RS06645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AVIN_RS06655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVIN_RS06670	COG1805	sodium ion transport
AVIN_RS06685	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVIN_RS06695	COG1477	protein flavinylation
AVIN_RS06705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVIN_RS06710	COG0584	glycerophosphoryl diester phosphodiesterase
AVIN_RS06720	COG1136	(ABC) transporter
AVIN_RS06725	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVIN_RS06735	COG0658	competence protein
AVIN_RS06735	COG2333	competence protein COMEC
AVIN_RS06740	COG0811	peptide transport
AVIN_RS06745	COG0848	biopolymer transport protein
AVIN_RS06750	COG1663	tetraacyldisaccharide 4'-kinase activity
AVIN_RS06755	COG2835	tetraacyldisaccharide 4'-kinase activity
AVIN_RS06765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVIN_RS06770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVIN_RS06775	COG1530	ribonuclease E activity
AVIN_RS06785	COG0546	phosphoglycolate phosphatase activity
AVIN_RS06790	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVIN_RS06790	COG0616	signal peptide processing
AVIN_RS06795	COG0424	maF-like protein
AVIN_RS06805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVIN_RS06810	COG0416	fatty acid biosynthetic process
AVIN_RS06825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVIN_RS06830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVIN_RS06840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVIN_RS06860	COG0084	hydrolase, TatD family'
AVIN_RS06870	COG3293	Transposase
AVIN_RS06875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVIN_RS06885	COG1355	regulation of microtubule-based process
AVIN_RS06890	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS06895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVIN_RS06900	COG2267	carboxylic ester hydrolase activity
AVIN_RS06905	COG1414	Transcriptional regulator
AVIN_RS06910	COG3971	2-oxopent-4-enoate hydratase activity
AVIN_RS06915	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AVIN_RS06920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS06925	COG2814	Major facilitator Superfamily
AVIN_RS06985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVIN_RS06990	COG1764	response to oxidative stress
AVIN_RS06995	COG1846	Transcriptional regulator
AVIN_RS07005	COG0730	response to heat
AVIN_RS07020	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVIN_RS07030	COG0500	methyltransferase
AVIN_RS07040	COG0501	Belongs to the peptidase M48B family
AVIN_RS07045	COG0436	Aminotransferase
AVIN_RS07050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVIN_RS07055	COG0386	Belongs to the glutathione peroxidase family
AVIN_RS07060	COG3437	response regulator, receiver
AVIN_RS07060	COG2205	protein histidine kinase activity
AVIN_RS07060	COG4999	Histidine kinase
AVIN_RS07060	COG3850	Histidine kinase
AVIN_RS07090	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS07095	COG1131	(ABC) transporter
AVIN_RS07100	COG0842	Transport permease protein
AVIN_RS07115	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVIN_RS07115	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVIN_RS07120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVIN_RS07125	COG0727	PFAM Uncharacterised protein family (UPF0153)
AVIN_RS07130	COG0778	Nitroreductase
AVIN_RS07135	COG0642	Histidine kinase
AVIN_RS07145	COG0745	RESPONSE REGULATOR receiver
AVIN_RS07150	COG2350	Protein conserved in bacteria
AVIN_RS07155	COG2917	probably involved in intracellular septation
AVIN_RS07160	COG0613	PHP domain protein
AVIN_RS07165	COG0009	L-threonylcarbamoyladenylate synthase
AVIN_RS07170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVIN_RS07175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVIN_RS07200	COG0800	Aldolase
AVIN_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS07215	COG0546	phosphoglycolate phosphatase activity
AVIN_RS07220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVIN_RS07225	COG0402	S-adenosylhomocysteine deaminase activity
AVIN_RS07230	COG0675	Transposase, IS605 OrfB family
AVIN_RS07235	COG3415	Transposase
AVIN_RS07235	COG2801	Transposase and inactivated derivatives
AVIN_RS07240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AVIN_RS07250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVIN_RS07265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVIN_RS07270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVIN_RS07280	COG0776	regulation of translation
AVIN_RS07290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AVIN_RS07300	COG1088	dTDP-glucose 4,6-dehydratase activity
AVIN_RS07320	COG1682	transport, permease protein
AVIN_RS07385	COG1450	Type ii and iii secretion system protein
AVIN_RS07430	COG1459	type II secretion system
AVIN_RS07435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVIN_RS07460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVIN_RS07470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVIN_RS07480	COG1643	Atp-dependent helicase
AVIN_RS07485	COG2161	toxin-antitoxin pair type II binding
AVIN_RS07520	COG2814	Major facilitator Superfamily
AVIN_RS07530	COG0183	Belongs to the thiolase family
AVIN_RS07535	COG1024	Enoyl-CoA hydratase
AVIN_RS07535	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS07540	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS07560	COG0427	acetyl-CoA hydrolase
AVIN_RS07565	COG2801	Transposase and inactivated derivatives
AVIN_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS07615	COG2801	Transposase and inactivated derivatives
AVIN_RS07630	COG1063	alcohol dehydrogenase
AVIN_RS07650	COG0166	Belongs to the GPI family
AVIN_RS07660	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS07675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVIN_RS07680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVIN_RS07685	COG0427	acetyl-CoA hydrolase
AVIN_RS07690	COG0583	DNA-binding transcription factor activity
AVIN_RS07695	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS07705	COG0842	Transport permease protein
AVIN_RS07710	COG1129	ABC transporter
AVIN_RS07710	COG0842	Transport permease protein
AVIN_RS07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVIN_RS07720	COG0675	Transposase, IS605 OrfB family
AVIN_RS07725	COG0167	dihydroorotate dehydrogenase activity
AVIN_RS07730	COG0604	alcohol dehydrogenase
AVIN_RS07730	COG3321	synthase
AVIN_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS07750	COG4221	oxidoreductase activity
AVIN_RS07760	COG2133	pyrroloquinoline quinone binding
AVIN_RS07845	COG0583	DNA-binding transcription factor activity
AVIN_RS07860	COG2851	Citrate transporter
AVIN_RS07895	COG1857	crispr-associated protein
AVIN_RS07915	COG4680	protein conserved in bacteria
AVIN_RS07935	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS07940	COG2814	Major facilitator Superfamily
AVIN_RS07955	COG2197	response regulator
AVIN_RS07960	COG4585	Histidine kinase
AVIN_RS07965	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS07965	COG1024	Enoyl-CoA hydratase
AVIN_RS07970	COG0183	Belongs to the thiolase family
AVIN_RS07975	COG0318	PFAM AMP-dependent synthetase and ligase
AVIN_RS07980	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS08000	COG0003	Pfam Anion-transporting ATPase
AVIN_RS08010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVIN_RS08035	COG3639	organic phosphonate transmembrane transporter activity
AVIN_RS08040	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVIN_RS08055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVIN_RS08060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVIN_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS08075	COG2610	gluconate transmembrane transporter activity
AVIN_RS08080	COG3604	Transcriptional regulator
AVIN_RS08100	COG0166	Belongs to the GPI family
AVIN_RS08105	COG0738	Major facilitator superfamily
AVIN_RS08140	COG2814	Major facilitator Superfamily
AVIN_RS08150	COG0583	DNA-binding transcription factor activity
AVIN_RS08155	COG3642	lipopolysaccharide core region biosynthetic process
AVIN_RS08165	COG5002	protein histidine kinase activity
AVIN_RS08165	COG3850	Histidine kinase
AVIN_RS08180	COG4067	protein conserved in archaea
AVIN_RS08180	COG0189	ligase activity
AVIN_RS08195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVIN_RS08195	COG0574	Belongs to the PEP-utilizing enzyme family
AVIN_RS08205	COG3002	Belongs to the UPF0753 family
AVIN_RS08240	COG1278	Cold shock
AVIN_RS08260	COG1403	HNH endonuclease
AVIN_RS08265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVIN_RS08270	COG4191	Histidine kinase
AVIN_RS08280	COG0477	Major facilitator Superfamily
AVIN_RS08295	COG3416	Protein conserved in bacteria
AVIN_RS08300	COG2824	Alkylphosphonate utilization operon protein PhnA
AVIN_RS08335	COG0217	transcriptional regulatory protein
AVIN_RS08360	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AVIN_RS08365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVIN_RS08380	COG0826	peptidase U32
AVIN_RS08435	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS08445	COG1309	transcriptional regulator
AVIN_RS08450	COG0604	alcohol dehydrogenase
AVIN_RS08525	COG0642	Histidine kinase
AVIN_RS08535	COG2900	Belongs to the SlyX family
AVIN_RS08540	COG0747	negative chemotaxis
AVIN_RS08545	COG0601	transmembrane transport
AVIN_RS08550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVIN_RS08560	COG3139	Protein of unknown function (DUF1315)
AVIN_RS08570	COG0308	aminopeptidase N
AVIN_RS08575	COG0427	acetyl-CoA hydrolase
AVIN_RS08580	COG3344	reverse transcriptase
AVIN_RS08615	COG0714	Associated with various cellular activities
AVIN_RS08625	COG0392	lysyltransferase activity
AVIN_RS08625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AVIN_RS08650	COG0167	dihydroorotate dehydrogenase activity
AVIN_RS08655	COG3130	regulation of translation
AVIN_RS08660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVIN_RS08660	COG0116	Belongs to the methyltransferase superfamily
AVIN_RS08665	COG2027	D-alanyl-D-alanine carboxypeptidase
AVIN_RS08700	COG1525	nuclease
AVIN_RS08740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVIN_RS08745	COG0513	Belongs to the DEAD box helicase family
AVIN_RS08750	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AVIN_RS08755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVIN_RS08760	COG5265	(ABC) transporter
AVIN_RS08765	COG0583	DNA-binding transcription factor activity
AVIN_RS08810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVIN_RS08820	COG4659	FMN binding
AVIN_RS08825	COG4658	electron transport chain
AVIN_RS08835	COG2878	Part of a membrane complex involved in electron transport
AVIN_RS08840	COG4657	Part of a membrane complex involved in electron transport
AVIN_RS08845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVIN_RS08845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVIN_RS08850	COG0489	protein tyrosine kinase activity
AVIN_RS08855	COG0717	Belongs to the dCTP deaminase family
AVIN_RS08900	COG3012	SEC-C Motif Domain Protein
AVIN_RS08920	COG1199	ATP-dependent helicase activity
AVIN_RS08940	COG0259	pyridoxamine-phosphate oxidase activity
AVIN_RS08950	COG3133	Outer membrane lipoprotein
AVIN_RS08955	COG2111	Na H antiporter
AVIN_RS08955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVIN_RS08960	COG1006	Multisubunit Na H antiporter MnhC subunit
AVIN_RS08965	COG0651	ATP synthesis coupled electron transport
AVIN_RS08970	COG1863	multisubunit Na H antiporter MnhE subunit
AVIN_RS08975	COG2212	antiporter activity
AVIN_RS08980	COG1320	monovalent cation:proton antiporter activity
AVIN_RS09025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVIN_RS09030	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVIN_RS09045	COG0356	it plays a direct role in the translocation of protons across the membrane
AVIN_RS09055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVIN_RS09055	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVIN_RS09060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVIN_RS09070	COG3639	organic phosphonate transmembrane transporter activity
AVIN_RS09075	COG3639	organic phosphonate transmembrane transporter activity
AVIN_RS09085	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AVIN_RS09095	COG3622	Belongs to the hyi family
AVIN_RS09100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVIN_RS09105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVIN_RS09110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVIN_RS09125	COG1294	oxidase, subunit
AVIN_RS09135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVIN_RS09165	COG0348	domain, Protein
AVIN_RS09170	COG2010	Cytochrome c
AVIN_RS09185	COG3278	Belongs to the heme-copper respiratory oxidase family
AVIN_RS09205	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AVIN_RS09235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVIN_RS09240	COG0668	transmembrane transport
AVIN_RS09245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVIN_RS09255	COG0564	pseudouridine synthase activity
AVIN_RS09260	COG0071	Belongs to the small heat shock protein (HSP20) family
AVIN_RS09275	COG1414	Transcriptional regulator
AVIN_RS09280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVIN_RS09285	COG1053	succinate dehydrogenase
AVIN_RS09295	COG1053	succinate dehydrogenase
AVIN_RS09315	COG1063	alcohol dehydrogenase
AVIN_RS09335	COG1053	succinate dehydrogenase
AVIN_RS09355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVIN_RS09375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVIN_RS09385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVIN_RS09390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVIN_RS09395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVIN_RS09400	COG0072	phenylalanine-tRNA ligase activity
AVIN_RS09405	COG0776	regulation of translation
AVIN_RS09445	COG2801	Transposase and inactivated derivatives
AVIN_RS09455	COG2853	Lipoprotein
AVIN_RS09460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVIN_RS09465	COG0142	geranyltranstransferase activity
AVIN_RS09470	COG1722	exodeoxyribonuclease VII activity
AVIN_RS09480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVIN_RS09485	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AVIN_RS09525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVIN_RS09540	COG1657	PFAM Prenyltransferase squalene oxidase
AVIN_RS09560	COG0583	DNA-binding transcription factor activity
AVIN_RS09570	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS09575	COG2814	Major facilitator Superfamily
AVIN_RS09585	COG4396	Host-nuclease inhibitor protein Gam
AVIN_RS09600	COG0145	ligase activity
AVIN_RS09605	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AVIN_RS09610	COG4647	ligase activity
AVIN_RS09615	COG3284	Transcriptional regulator
AVIN_RS09630	COG1045	serine acetyltransferase
AVIN_RS09635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVIN_RS09640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVIN_RS09650	COG2801	Transposase and inactivated derivatives
AVIN_RS09650	COG3415	Transposase
AVIN_RS09660	COG1024	Enoyl-CoA hydratase
AVIN_RS09675	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AVIN_RS09680	COG4266	Belongs to the allantoicase family
AVIN_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVIN_RS09720	COG1535	isochorismatase
AVIN_RS09720	COG3433	isochorismatase activity
AVIN_RS09725	COG1021	2,3-dihydroxybenzoate-AMP ligase
AVIN_RS09730	COG1169	isochorismate synthase
AVIN_RS09745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVIN_RS09770	COG3842	ATPase activity
AVIN_RS09780	COG1053	succinate dehydrogenase
AVIN_RS09790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS09805	COG0583	DNA-binding transcription factor activity
AVIN_RS09815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AVIN_RS09820	COG0277	FAD linked oxidase domain protein
AVIN_RS09825	COG0436	Aminotransferase
AVIN_RS09830	COG0765	amino acid transport
AVIN_RS09835	COG0765	amino acid transport
AVIN_RS09840	COG1126	abc transporter atp-binding protein
AVIN_RS09850	COG0625	glutathione transferase activity
AVIN_RS09870	COG3712	iron ion homeostasis
AVIN_RS09875	COG1595	DNA-templated transcription, initiation
AVIN_RS09885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS09890	COG0235	Class ii aldolase
AVIN_RS09895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS09900	COG1116	anion transmembrane transporter activity
AVIN_RS09905	COG4206	TonB-dependent receptor
AVIN_RS09915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS09920	COG0583	DNA-binding transcription factor activity
AVIN_RS09940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS09945	COG0667	Aldo Keto reductase
AVIN_RS09950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS09970	COG4771	TonB-dependent receptor
AVIN_RS09975	COG1609	Transcriptional regulator
AVIN_RS09980	COG5642	Protein of unknown function (DUF2384)
AVIN_RS09985	COG5654	RES domain protein
AVIN_RS10005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS10015	COG2175	clavaminate synthase activity
AVIN_RS10025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS10030	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS10045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVIN_RS10055	COG0596	Alpha beta hydrolase
AVIN_RS10060	COG2175	clavaminate synthase activity
AVIN_RS10080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVIN_RS10090	COG1063	alcohol dehydrogenase
AVIN_RS10105	COG2376	Dihydroxyacetone kinase
AVIN_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS10115	COG1879	ABC-type sugar transport system periplasmic component
AVIN_RS10120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVIN_RS10125	COG1129	ABC transporter
AVIN_RS10130	COG0698	ribose 5-phosphate isomerase
AVIN_RS10135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVIN_RS10145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVIN_RS10165	COG0148	phosphopyruvate hydratase activity
AVIN_RS10170	COG4566	intracellular signal transduction
AVIN_RS10180	COG0318	PFAM AMP-dependent synthetase and ligase
AVIN_RS10185	COG0402	S-adenosylhomocysteine deaminase activity
AVIN_RS10195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVIN_RS10205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVIN_RS10210	COG3415	Transposase
AVIN_RS10210	COG2801	Transposase and inactivated derivatives
AVIN_RS10230	COG0667	Aldo Keto reductase
AVIN_RS10235	COG0625	glutathione transferase activity
AVIN_RS10240	COG2175	clavaminate synthase activity
AVIN_RS10245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS10275	COG3265	gluconokinase activity
AVIN_RS10290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS10295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS10300	COG1116	anion transmembrane transporter activity
AVIN_RS10300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS10325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVIN_RS10330	COG0625	glutathione transferase activity
AVIN_RS10335	COG4774	siderophore transport
AVIN_RS10340	COG3712	iron ion homeostasis
AVIN_RS10345	COG1595	DNA-templated transcription, initiation
AVIN_RS10375	COG2217	Heavy metal translocating P-type atpase
AVIN_RS10400	COG0783	Belongs to the Dps family
AVIN_RS10435	COG3204	pilus organization
AVIN_RS10455	COG3409	Peptidoglycan-binding domain 1 protein
AVIN_RS10455	COG3267	Type II secretory pathway component ExeA
AVIN_RS10500	COG0084	hydrolase, TatD family'
AVIN_RS10505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AVIN_RS10520	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVIN_RS10525	COG4181	ATPase activity
AVIN_RS10575	COG0189	ligase activity
AVIN_RS10590	COG1802	Transcriptional regulator
AVIN_RS10615	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVIN_RS10625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVIN_RS10635	COG0668	transmembrane transport
AVIN_RS10655	COG0243	molybdopterin cofactor binding
AVIN_RS10660	COG2146	nitrite reductase [NAD(P)H] activity
AVIN_RS10665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVIN_RS10670	COG0515	serine threonine protein kinase
AVIN_RS10670	COG2815	serine threonine protein kinase
AVIN_RS10675	COG2223	nitrite transmembrane transporter activity
AVIN_RS10695	COG0436	Aminotransferase
AVIN_RS10705	COG3707	response regulator
AVIN_RS10710	COG1116	anion transmembrane transporter activity
AVIN_RS10710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS10730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVIN_RS10740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVIN_RS10745	COG0215	cysteine-tRNA ligase activity
AVIN_RS10750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVIN_RS10770	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVIN_RS10780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVIN_RS10785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVIN_RS10800	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVIN_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS10825	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AVIN_RS10830	COG0302	gtp cyclohydrolase
AVIN_RS10845	COG1335	isochorismatase
AVIN_RS10860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVIN_RS10870	COG0235	Class ii aldolase
AVIN_RS10880	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AVIN_RS10890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVIN_RS10910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVIN_RS10950	COG3293	Transposase
AVIN_RS10975	COG1815	bacterial-type flagellum-dependent cell motility
AVIN_RS10980	COG1558	bacterial-type flagellum-dependent cell motility
AVIN_RS10985	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVIN_RS10995	COG4787	bacterial-type flagellum-dependent cell motility
AVIN_RS11005	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVIN_RS11010	COG1706	bacterial-type flagellum-dependent cell motility
AVIN_RS11015	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVIN_RS11015	COG3951	Flagellar rod assembly protein muramidase FlgJ
AVIN_RS11055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVIN_RS11090	COG1766	The M ring may be actively involved in energy transduction
AVIN_RS11095	COG1677	Flagellar hook-basal body complex protein FliE
AVIN_RS11120	COG2257	FlhB HrpN YscU SpaS Family
AVIN_RS11140	COG1360	Flagellar Motor Protein
AVIN_RS11145	COG2198	Histidine kinase
AVIN_RS11145	COG0643	Histidine kinase
AVIN_RS11150	COG0835	chemotaxis
AVIN_RS11155	COG0840	transmembrane signaling receptor activity
AVIN_RS11160	COG0840	transmembrane signaling receptor activity
AVIN_RS11165	COG0840	transmembrane signaling receptor activity
AVIN_RS11180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVIN_RS11190	COG0747	negative chemotaxis
AVIN_RS11220	COG2205	protein histidine kinase activity
AVIN_RS11225	COG0745	RESPONSE REGULATOR receiver
AVIN_RS11230	COG3158	transport of potassium into the cell
AVIN_RS11255	COG3344	reverse transcriptase
AVIN_RS11290	COG2814	Major facilitator Superfamily
AVIN_RS11310	COG3344	reverse transcriptase
AVIN_RS11325	COG0604	alcohol dehydrogenase
AVIN_RS11335	COG0392	lysyltransferase activity
AVIN_RS11340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVIN_RS11345	COG3568	Endonuclease Exonuclease Phosphatase
AVIN_RS11380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVIN_RS11385	COG0297	glycogen (starch) synthase activity
AVIN_RS11390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVIN_RS11395	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS11400	COG0477	Major facilitator Superfamily
AVIN_RS11405	COG0583	DNA-binding transcription factor activity
AVIN_RS11410	COG0659	secondary active sulfate transmembrane transporter activity
AVIN_RS11450	COG0322	excinuclease ABC activity
AVIN_RS11470	COG1309	transcriptional regulator
AVIN_RS11525	COG2198	Histidine kinase
AVIN_RS11525	COG0784	Response regulator, receiver
AVIN_RS11525	COG2205	protein histidine kinase activity
AVIN_RS11535	COG2202	Pas domain
AVIN_RS11535	COG2200	EAL domain
AVIN_RS11535	COG2199	diguanylate cyclase activity
AVIN_RS11555	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS11560	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS11565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVIN_RS11575	COG0318	PFAM AMP-dependent synthetase and ligase
AVIN_RS11580	COG4191	Histidine kinase
AVIN_RS11615	COG4566	intracellular signal transduction
AVIN_RS11620	COG1309	transcriptional regulator
AVIN_RS11625	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVIN_RS11760	COG0069	glutamate synthase activity
AVIN_RS11795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVIN_RS11795	COG0543	2 iron, 2 sulfur cluster binding
AVIN_RS11800	COG0071	Belongs to the small heat shock protein (HSP20) family
AVIN_RS11805	COG0459	protein refolding
AVIN_RS11810	COG0589	response to stress
AVIN_RS11825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AVIN_RS11830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVIN_RS11830	COG2010	Cytochrome c
AVIN_RS11840	COG0667	Aldo Keto reductase
AVIN_RS11845	COG0583	DNA-binding transcription factor activity
AVIN_RS11850	COG1368	sulfuric ester hydrolase activity
AVIN_RS11855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AVIN_RS11860	COG1742	UPF0060 membrane protein
AVIN_RS11865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVIN_RS11870	COG0640	Transcriptional regulator
AVIN_RS11890	COG2271	Major facilitator Superfamily
AVIN_RS11895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS11900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVIN_RS11915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVIN_RS11915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVIN_RS11920	COG1760	l-serine dehydratase
AVIN_RS11925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVIN_RS11975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AVIN_RS11980	COG1609	Transcriptional regulator
AVIN_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS12015	COG5642	Protein of unknown function (DUF2384)
AVIN_RS12025	COG2986	histidine ammonia-lyase
AVIN_RS12030	COG0402	S-adenosylhomocysteine deaminase activity
AVIN_RS12080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVIN_RS12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVIN_RS12090	COG1120	ATPase activity
AVIN_RS12105	COG2267	carboxylic ester hydrolase activity
AVIN_RS12210	COG0515	serine threonine protein kinase
AVIN_RS12270	COG0477	Major facilitator Superfamily
AVIN_RS12275	COG0579	oxidoreductase
AVIN_RS12285	COG0579	oxidoreductase
AVIN_RS12290	COG2186	Transcriptional regulator
AVIN_RS12295	COG1609	Transcriptional regulator
AVIN_RS12305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVIN_RS12325	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS12360	COG0483	inositol monophosphate 1-phosphatase activity
AVIN_RS12365	COG0612	Peptidase, M16
AVIN_RS12385	COG1611	Belongs to the LOG family
AVIN_RS12395	COG2814	Major facilitator Superfamily
AVIN_RS12420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVIN_RS12425	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS12435	COG0148	phosphopyruvate hydratase activity
AVIN_RS12445	COG0800	Aldolase
AVIN_RS12455	COG1737	Transcriptional regulator
AVIN_RS12465	COG1609	Transcriptional regulator
AVIN_RS12470	COG3265	gluconokinase activity
AVIN_RS12475	COG1070	Carbohydrate kinase
AVIN_RS12480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVIN_RS12490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVIN_RS12505	COG0395	ABC-type sugar transport system, permease component
AVIN_RS12510	COG1175	transmembrane transport
AVIN_RS12520	COG4977	sequence-specific DNA binding
AVIN_RS12520	COG1917	Cupin 2, conserved barrel domain protein
AVIN_RS12525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AVIN_RS12530	COG2706	6-phosphogluconolactonase activity
AVIN_RS12550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVIN_RS12570	COG3344	reverse transcriptase
AVIN_RS12575	COG0616	signal peptide processing
AVIN_RS12590	COG2816	NAD+ diphosphatase activity
AVIN_RS12655	COG1215	transferase activity, transferring glycosyl groups
AVIN_RS12685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVIN_RS12710	COG1334	flagellar protein FlaG
AVIN_RS12715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVIN_RS12720	COG1191	sigma factor activity
AVIN_RS12740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVIN_RS12745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVIN_RS12750	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVIN_RS12755	COG0745	RESPONSE REGULATOR receiver
AVIN_RS12760	COG0840	transmembrane signaling receptor activity
AVIN_RS12765	COG0840	transmembrane signaling receptor activity
AVIN_RS12770	COG2201	protein-glutamate methylesterase activity
AVIN_RS12775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVIN_RS12780	COG0366	Alpha amylase catalytic
AVIN_RS12790	COG1944	ATP diphosphatase activity
AVIN_RS12795	COG2081	HI0933 family
AVIN_RS12855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVIN_RS12860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVIN_RS12860	COG1648	precorrin-2 dehydrogenase activity
AVIN_RS12865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVIN_RS12870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVIN_RS12875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVIN_RS12880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVIN_RS12890	COG0492	ferredoxin-NADP+ reductase activity
AVIN_RS12895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVIN_RS12900	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVIN_RS12905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVIN_RS12910	COG0542	response to heat
AVIN_RS12915	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVIN_RS12920	COG1278	Cold shock
AVIN_RS12945	COG0482	sulfurtransferase activity
AVIN_RS12950	COG2915	High frequency lysogenization protein hflD homolog
AVIN_RS12960	COG2850	peptidyl-arginine hydroxylation
AVIN_RS12985	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVIN_RS12990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVIN_RS12995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVIN_RS12995	COG0649	NAD binding
AVIN_RS13015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVIN_RS13020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVIN_RS13030	COG0713	ATP synthesis coupled electron transport
AVIN_RS13045	COG1007	ATP synthesis coupled electron transport
AVIN_RS13060	COG3212	peptidase
AVIN_RS13065	COG0720	synthase
AVIN_RS13070	COG0741	lytic transglycosylase activity
AVIN_RS13080	COG1459	type II secretion system
AVIN_RS13095	COG2135	peptidase activity
AVIN_RS13105	COG0488	(ABC) transporter
AVIN_RS13110	COG1968	undecaprenyl-diphosphatase activity
AVIN_RS13120	COG0316	Belongs to the HesB IscA family
AVIN_RS13120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AVIN_RS13130	COG1538	Outer membrane efflux protein
AVIN_RS13155	COG1115	amino acid carrier protein
AVIN_RS13160	COG2911	Protein conserved in bacteria
AVIN_RS13165	COG0729	surface antigen
AVIN_RS13195	COG0300	oxidoreductase activity
AVIN_RS13210	COG0300	oxidoreductase activity
AVIN_RS13220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVIN_RS13235	COG4191	Histidine kinase
AVIN_RS13245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVIN_RS13250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVIN_RS13305	COG0745	RESPONSE REGULATOR receiver
AVIN_RS13320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVIN_RS13330	COG1469	GTP cyclohydrolase I activity
AVIN_RS13355	COG1653	transport
AVIN_RS13360	COG0784	Response regulator, receiver
AVIN_RS13360	COG2205	protein histidine kinase activity
AVIN_RS13360	COG5002	protein histidine kinase activity
AVIN_RS13370	COG0322	excinuclease ABC activity
AVIN_RS13375	COG4702	Belongs to the UPF0303 family
AVIN_RS13390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVIN_RS13415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS13420	COG1116	anion transmembrane transporter activity
AVIN_RS13425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS13435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVIN_RS13455	COG0577	efflux transmembrane transporter activity
AVIN_RS13495	COG0328	RNA-DNA hybrid ribonuclease activity
AVIN_RS13510	COG1388	LysM domain
AVIN_RS13510	COG0741	lytic transglycosylase activity
AVIN_RS13520	COG4166	transmembrane transport
AVIN_RS13525	COG4174	ABC transporter (Permease)
AVIN_RS13530	COG4239	(ABC) transporter, permease
AVIN_RS13535	COG4172	Belongs to the ABC transporter superfamily
AVIN_RS13545	COG2233	PERMEase
AVIN_RS13565	COG0045	succinate-CoA ligase (ADP-forming) activity
AVIN_RS13590	COG1053	succinate dehydrogenase
AVIN_RS13595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVIN_RS13600	COG2009	succinate dehydrogenase
AVIN_RS13625	COG3123	guanosine phosphorylase activity
AVIN_RS13635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVIN_RS13650	COG3206	protein involved in exopolysaccharide biosynthesis
AVIN_RS13650	COG0489	protein tyrosine kinase activity
AVIN_RS13655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVIN_RS13660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVIN_RS13665	COG1132	(ABC) transporter
AVIN_RS13670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AVIN_RS13685	COG0463	Glycosyl transferase, family 2
AVIN_RS13695	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS13700	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS13705	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS13720	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS13725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVIN_RS13735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVIN_RS13750	COG1216	Glycosyl transferase, family 2
AVIN_RS13755	COG1442	glycosyl transferase family 8
AVIN_RS13755	COG1216	Glycosyl transferase, family 2
AVIN_RS13765	COG0318	PFAM AMP-dependent synthetase and ligase
AVIN_RS13770	COG2030	dehydratase
AVIN_RS13775	COG0402	S-adenosylhomocysteine deaminase activity
AVIN_RS13790	COG0673	inositol 2-dehydrogenase activity
AVIN_RS13810	COG1053	succinate dehydrogenase
AVIN_RS13820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVIN_RS13825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVIN_RS13830	COG3115	cell septum assembly
AVIN_RS13835	COG1196	nuclear chromosome segregation
AVIN_RS13840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVIN_RS13875	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AVIN_RS13930	COG1116	anion transmembrane transporter activity
AVIN_RS13935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS13940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS13945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS13950	COG0431	NADPH-dependent FMN reductase
AVIN_RS13955	COG0450	alkyl hydroperoxide reductase
AVIN_RS13960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AVIN_RS13975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS13980	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AVIN_RS14010	COG3550	peptidyl-serine autophosphorylation
AVIN_RS14030	COG0798	PFAM Bile acid sodium symporter
AVIN_RS14045	COG2871	sodium ion transport
AVIN_RS14115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVIN_RS14125	COG4221	oxidoreductase activity
AVIN_RS14130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS14135	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVIN_RS14145	COG2175	clavaminate synthase activity
AVIN_RS14155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVIN_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS14215	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS14230	COG1116	anion transmembrane transporter activity
AVIN_RS14235	COG2205	protein histidine kinase activity
AVIN_RS14240	COG0745	RESPONSE REGULATOR receiver
AVIN_RS14255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AVIN_RS14265	COG1301	dicarboxylic acid transport
AVIN_RS14270	COG0583	DNA-binding transcription factor activity
AVIN_RS14285	COG3384	dioxygenase
AVIN_RS14290	COG0583	DNA-binding transcription factor activity
AVIN_RS14295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AVIN_RS14300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVIN_RS14305	COG2828	Protein conserved in bacteria
AVIN_RS14320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS14340	COG0235	Class ii aldolase
AVIN_RS14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS14355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS14365	COG0673	inositol 2-dehydrogenase activity
AVIN_RS14375	COG1335	isochorismatase
AVIN_RS14405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVIN_RS14410	COG2011	ABC-type metal ion transport system permease component
AVIN_RS14425	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AVIN_RS14430	COG1518	maintenance of DNA repeat elements
AVIN_RS14470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS14490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AVIN_RS14495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVIN_RS14500	COG4208	sulfate ABC transporter
AVIN_RS14510	COG3781	membrane
AVIN_RS14550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVIN_RS14560	COG4118	positive regulation of growth
AVIN_RS14575	COG4680	protein conserved in bacteria
AVIN_RS14605	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AVIN_RS14645	COG3385	transposase activity
AVIN_RS14675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVIN_RS14680	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS14685	COG3039	Transposase
AVIN_RS14710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS14730	COG1073	alpha beta
AVIN_RS14745	COG2814	Major facilitator Superfamily
AVIN_RS14750	COG1064	alcohol dehydrogenase
AVIN_RS14775	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS14780	COG2207	Transcriptional regulator
AVIN_RS14795	COG0667	Aldo Keto reductase
AVIN_RS14805	COG0300	oxidoreductase activity
AVIN_RS14810	COG0667	Aldo Keto reductase
AVIN_RS14820	COG0667	Aldo Keto reductase
AVIN_RS14860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVIN_RS14865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVIN_RS14875	COG0745	RESPONSE REGULATOR receiver
AVIN_RS14880	COG2853	Lipoprotein
AVIN_RS14915	COG0514	ATP-dependent DNA helicase (RecQ)
AVIN_RS14925	COG2832	Protein of unknown function (DUF454)
AVIN_RS14935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVIN_RS14950	COG0121	glutamine amidotransferase
AVIN_RS14965	COG1295	ribonuclease BN
AVIN_RS14975	COG2983	Belongs to the UPF0260 family
AVIN_RS14985	COG3100	YcgL domain-containing protein
AVIN_RS15015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AVIN_RS15020	COG0406	alpha-ribazole phosphatase activity
AVIN_RS15025	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AVIN_RS15035	COG1492	cobalamin metabolic process
AVIN_RS15045	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AVIN_RS15050	COG0778	Nitroreductase
AVIN_RS15055	COG1797	cobyrinic acid a,c-diamide synthase activity
AVIN_RS15070	COG4206	TonB-dependent receptor
AVIN_RS15075	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVIN_RS15080	COG0505	Belongs to the CarA family
AVIN_RS15085	COG0791	NLP P60 protein
AVIN_RS15090	COG0791	NLP P60 protein
AVIN_RS15105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVIN_RS15110	COG0037	tRNA processing
AVIN_RS15120	COG3091	SprT-like family
AVIN_RS15140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVIN_RS15140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVIN_RS15145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVIN_RS15155	COG3293	Transposase
AVIN_RS15170	COG1943	Transposase
AVIN_RS15175	COG2226	methyltransferase
AVIN_RS15220	COG0861	Integral membrane protein TerC family
AVIN_RS15255	COG3415	Transposase
AVIN_RS15255	COG2801	Transposase and inactivated derivatives
AVIN_RS15280	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS15300	COG1609	Transcriptional regulator
AVIN_RS15310	COG0477	Major facilitator Superfamily
AVIN_RS15310	COG2814	Major facilitator Superfamily
AVIN_RS15315	COG1082	Xylose isomerase domain protein TIM barrel
AVIN_RS15340	COG0583	DNA-binding transcription factor activity
AVIN_RS15350	COG2031	fatty acid transporter
AVIN_RS15355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS15365	COG1785	Belongs to the alkaline phosphatase family
AVIN_RS15375	COG0604	alcohol dehydrogenase
AVIN_RS15400	COG2084	Dehydrogenase
AVIN_RS15415	COG1609	Transcriptional regulator
AVIN_RS15455	COG0705	Rhomboid family
AVIN_RS15460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVIN_RS15465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVIN_RS15515	COG1286	toxin biosynthetic process
AVIN_RS15525	COG0285	dihydrofolate synthase activity
AVIN_RS15530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVIN_RS15535	COG0135	phosphoribosylanthranilate isomerase activity
AVIN_RS15560	COG0473	3-isopropylmalate dehydrogenase activity
AVIN_RS15570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVIN_RS15590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVIN_RS15600	COG0800	Aldolase
AVIN_RS15610	COG0745	RESPONSE REGULATOR receiver
AVIN_RS15645	COG2239	Acts as a magnesium transporter
AVIN_RS15670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AVIN_RS15680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVIN_RS15700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVIN_RS15710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVIN_RS15720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVIN_RS15725	COG2301	Belongs to the HpcH HpaI aldolase family
AVIN_RS15760	COG2154	pterin-4-alpha-carbinolamine dehydratase
AVIN_RS15840	COG0271	Belongs to the BolA IbaG family
AVIN_RS15850	COG0114	fumarate hydratase activity
AVIN_RS15875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVIN_RS15875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVIN_RS15880	COG1846	Transcriptional regulator
AVIN_RS15885	COG0367	asparagine synthase
AVIN_RS15890	COG0189	ligase activity
AVIN_RS15890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVIN_RS15895	COG1363	Peptidase, m42
AVIN_RS15905	COG3089	Belongs to the UPF0270 family
AVIN_RS15915	COG1253	flavin adenine dinucleotide binding
AVIN_RS15920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVIN_RS15925	COG3162	membrane
AVIN_RS15950	COG2853	Lipoprotein
AVIN_RS15955	COG1560	Kdo2-lipid A biosynthetic process
AVIN_RS15960	COG0850	regulation of cytokinetic process
AVIN_RS15965	COG2894	cell division
AVIN_RS15970	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVIN_RS15975	COG0564	pseudouridine synthase activity
AVIN_RS15980	COG1362	aminopeptidase activity
AVIN_RS15985	COG0604	alcohol dehydrogenase
AVIN_RS15985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVIN_RS15985	COG4221	oxidoreductase activity
AVIN_RS15985	COG3321	synthase
AVIN_RS16005	COG3339	Conserved Protein
AVIN_RS16010	COG0545	Peptidyl-prolyl cis-trans isomerase
AVIN_RS16030	COG2205	protein histidine kinase activity
AVIN_RS16035	COG3174	membrane
AVIN_RS16075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVIN_RS16080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AVIN_RS16085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVIN_RS16095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVIN_RS16100	COG0425	Belongs to the sulfur carrier protein TusA family
AVIN_RS16105	COG4783	chaperone-mediated protein folding
AVIN_RS16110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVIN_RS16120	COG0471	metal ion transport
AVIN_RS16135	COG1064	alcohol dehydrogenase
AVIN_RS16160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVIN_RS16220	COG3846	protein secretion by the type IV secretion system
AVIN_RS16235	COG3451	type IV secretory pathway VirB4
AVIN_RS16245	COG3838	Conjugal transfer protein Trbc
AVIN_RS16250	COG4962	Type ii secretion system protein e
AVIN_RS16270	COG0583	DNA-binding transcription factor activity
AVIN_RS16295	COG1309	transcriptional regulator
AVIN_RS16300	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVIN_RS16315	COG0583	DNA-binding transcription factor activity
AVIN_RS16320	COG2814	Major facilitator Superfamily
AVIN_RS16335	COG0583	DNA-binding transcription factor activity
AVIN_RS16340	COG2814	Major facilitator Superfamily
AVIN_RS16355	COG4959	Type IV secretory pathway protease TraF
AVIN_RS16400	COG2003	Belongs to the UPF0758 family
AVIN_RS16435	COG3657	addiction module killer protein
AVIN_RS16455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVIN_RS16465	COG3293	Transposase
AVIN_RS16545	COG2963	transposase activity
AVIN_RS16630	COG2801	Transposase and inactivated derivatives
AVIN_RS16675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVIN_RS16685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVIN_RS16690	COG0602	queuosine metabolic process
AVIN_RS16695	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVIN_RS16725	COG0824	Thioesterase
AVIN_RS16730	COG2255	four-way junction helicase activity
AVIN_RS16740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVIN_RS16750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVIN_RS16760	COG0442	prolyl-tRNA aminoacylation
AVIN_RS16780	COG1295	ribonuclease BN
AVIN_RS16800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVIN_RS16805	COG0628	permease
AVIN_RS16820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVIN_RS16825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVIN_RS16835	COG3077	Addiction module antitoxin, RelB DinJ family
AVIN_RS16845	COG3122	Protein conserved in bacteria
AVIN_RS16850	COG3956	TIGRFAM MazG family protein
AVIN_RS16870	COG2819	hydrolase of the alpha beta superfamily
AVIN_RS16875	COG0500	methyltransferase
AVIN_RS16900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVIN_RS16905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVIN_RS16915	COG2205	protein histidine kinase activity
AVIN_RS16915	COG5002	protein histidine kinase activity
AVIN_RS16915	COG0784	Response regulator, receiver
AVIN_RS16920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVIN_RS16970	COG3561	AntA/AntB antirepressor
AVIN_RS17150	COG4695	Portal protein
AVIN_RS17160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVIN_RS17175	COG2308	Evidence 4 Homologs of previously reported genes of
AVIN_RS17180	COG0693	protein deglycase activity
AVIN_RS17185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVIN_RS17215	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AVIN_RS17225	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS17240	COG5001	Diguanylate cyclase
AVIN_RS17240	COG3300	MHYT domain
AVIN_RS17265	COG2831	hemolysin activation secretion protein
AVIN_RS17285	COG0583	DNA-binding transcription factor activity
AVIN_RS17290	COG0604	alcohol dehydrogenase
AVIN_RS17290	COG3321	synthase
AVIN_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS17305	COG2814	Major facilitator Superfamily
AVIN_RS17320	COG0667	Aldo Keto reductase
AVIN_RS17325	COG0667	Aldo Keto reductase
AVIN_RS17340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVIN_RS17345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVIN_RS17350	COG1309	transcriptional regulator
AVIN_RS17355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AVIN_RS17355	COG1082	Xylose isomerase domain protein TIM barrel
AVIN_RS17370	COG0656	L-ascorbic acid biosynthetic process
AVIN_RS17380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVIN_RS17385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVIN_RS17400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVIN_RS17405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVIN_RS17410	COG1414	Transcriptional regulator
AVIN_RS17415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVIN_RS17420	COG3485	protocatechuate 3,4-dioxygenase
AVIN_RS17425	COG3485	protocatechuate 3,4-dioxygenase
AVIN_RS17430	COG0583	DNA-binding transcription factor activity
AVIN_RS17435	COG0788	formyltetrahydrofolate deformylase activity
AVIN_RS17445	COG2925	Exonuclease
AVIN_RS17470	COG0714	Associated with various cellular activities
AVIN_RS17485	COG0589	response to stress
AVIN_RS17495	COG3706	GGDEF domain
AVIN_RS17500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AVIN_RS17500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AVIN_RS17520	COG0583	DNA-binding transcription factor activity
AVIN_RS17530	COG3148	PFAM DTW domain containing protein
AVIN_RS17540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AVIN_RS17545	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AVIN_RS17555	COG2137	regulation of response to DNA damage stimulus
AVIN_RS17560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVIN_RS17565	COG1546	Belongs to the CinA family
AVIN_RS17600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVIN_RS17610	COG0840	transmembrane signaling receptor activity
AVIN_RS17615	COG0840	transmembrane signaling receptor activity
AVIN_RS17630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVIN_RS17635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVIN_RS17640	COG0585	pseudouridine synthase activity
AVIN_RS17645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVIN_RS17650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVIN_RS17655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVIN_RS17660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVIN_RS17675	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVIN_RS17680	COG0504	CTP synthase activity
AVIN_RS17690	COG0825	malonyl-CoA metabolic process
AVIN_RS17700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVIN_RS17705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVIN_RS17710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVIN_RS17715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVIN_RS17740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVIN_RS17750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVIN_RS17755	COG0233	cytoplasmic translational termination
AVIN_RS17760	COG0528	UMP kinase activity
AVIN_RS17765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVIN_RS17770	COG0052	Belongs to the universal ribosomal protein uS2 family
AVIN_RS17775	COG0024	Methionine aminopeptidase
AVIN_RS17780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVIN_RS17785	COG0436	Aminotransferase
AVIN_RS17790	COG0025	NhaP-type Na H and K H
AVIN_RS17815	COG1393	Belongs to the ArsC family
AVIN_RS17820	COG2171	N-acyltransferase activity
AVIN_RS17840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVIN_RS17855	COG2226	methyltransferase
AVIN_RS17880	COG1131	(ABC) transporter
AVIN_RS17890	COG0742	ribosomal rna small subunit methyltransferase
AVIN_RS17900	COG1801	Protein of unknown function DUF72
AVIN_RS17905	COG1214	PFAM Peptidase M22, glycoprotease
AVIN_RS17910	COG0563	adenylate kinase activity
AVIN_RS17915	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AVIN_RS17935	COG1073	alpha beta
AVIN_RS17960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVIN_RS17965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AVIN_RS17975	COG1902	pentaerythritol trinitrate reductase activity
AVIN_RS18020	COG1607	acyl-coa hydrolase
AVIN_RS18025	COG0335	large ribosomal subunit rRNA binding
AVIN_RS18030	COG0336	Belongs to the RNA methyltransferase TrmD family
AVIN_RS18035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVIN_RS18040	COG0228	four-way junction DNA binding
AVIN_RS18045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVIN_RS18055	COG4536	flavin adenine dinucleotide binding
AVIN_RS18060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVIN_RS18065	COG0494	nUDIX hydrolase
AVIN_RS18075	COG1388	LysM domain
AVIN_RS18075	COG1376	ErfK ybiS ycfS ynhG family protein
AVIN_RS18090	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AVIN_RS18100	COG2132	Multicopper oxidase
AVIN_RS18125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS18135	COG1570	exodeoxyribonuclease VII activity
AVIN_RS18145	COG0739	heme binding
AVIN_RS18195	COG0583	DNA-binding transcription factor activity
AVIN_RS18200	COG0402	S-adenosylhomocysteine deaminase activity
AVIN_RS18220	COG0477	Major facilitator Superfamily
AVIN_RS18230	COG2909	trisaccharide binding
AVIN_RS18235	COG0371	Dehydrogenase
AVIN_RS18245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVIN_RS18255	COG4993	Dehydrogenase
AVIN_RS18265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVIN_RS18280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS18285	COG2356	endonuclease I
AVIN_RS18290	COG3647	Membrane
AVIN_RS18305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVIN_RS18310	COG0436	Aminotransferase
AVIN_RS18330	COG1160	GTP binding
AVIN_RS18340	COG2976	Protein conserved in bacteria
AVIN_RS18345	COG0124	histidyl-tRNA synthetase
AVIN_RS18350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVIN_RS18370	COG0105	UTP biosynthetic process
AVIN_RS18385	COG0443	Heat shock 70 kDa protein
AVIN_RS18390	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVIN_RS18395	COG0316	Belongs to the HesB IscA family
AVIN_RS18405	COG1104	cysteine desulfurase activity
AVIN_RS18440	COG1862	Preprotein translocase
AVIN_RS18445	COG0343	queuine tRNA-ribosyltransferase activity
AVIN_RS18450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVIN_RS18460	COG0582	viral genome integration into host DNA
AVIN_RS18465	COG2801	Transposase and inactivated derivatives
AVIN_RS18505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVIN_RS18510	COG3657	addiction module killer protein
AVIN_RS18555	COG0268	Binds directly to 16S ribosomal RNA
AVIN_RS18565	COG3045	CreA protein
AVIN_RS18570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVIN_RS18575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVIN_RS18580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVIN_RS18585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVIN_RS18590	COG0142	geranyltranstransferase activity
AVIN_RS18595	COG0545	Peptidyl-prolyl cis-trans isomerase
AVIN_RS18600	COG2862	Uncharacterized protein family, UPF0114
AVIN_RS18610	COG1067	ATP-dependent peptidase activity
AVIN_RS18650	COG1595	DNA-templated transcription, initiation
AVIN_RS18655	COG0488	(ABC) transporter
AVIN_RS18660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVIN_RS18665	COG0523	cobalamin synthesis protein
AVIN_RS18670	COG2879	small protein
AVIN_RS18675	COG1966	Carbon starvation protein
AVIN_RS18690	COG2020	methyltransferase activity
AVIN_RS18705	COG1970	mechanosensitive ion channel activity
AVIN_RS18710	COG0386	Belongs to the glutathione peroxidase family
AVIN_RS18720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVIN_RS18735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVIN_RS18750	COG1525	nuclease
AVIN_RS18755	COG2205	protein histidine kinase activity
AVIN_RS18755	COG2198	Histidine kinase
AVIN_RS18755	COG0784	Response regulator, receiver
AVIN_RS18765	COG2989	Protein conserved in bacteria
AVIN_RS18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS18780	COG2813	Specifically methylates the guanine in position
AVIN_RS18785	COG2119	membrane
AVIN_RS18790	COG2119	membrane
AVIN_RS18795	COG0501	Belongs to the peptidase M48B family
AVIN_RS18800	COG2135	peptidase activity
AVIN_RS18835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVIN_RS18840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVIN_RS18845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVIN_RS18850	COG1090	epimerase
AVIN_RS18855	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AVIN_RS18865	COG0789	Transcriptional regulator
AVIN_RS18870	COG0415	Belongs to the DNA photolyase family
AVIN_RS18875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVIN_RS18880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVIN_RS18890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVIN_RS18895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVIN_RS18910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVIN_RS18925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVIN_RS18930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVIN_RS18935	COG0193	aminoacyl-tRNA hydrolase activity
AVIN_RS18970	COG1025	Belongs to the peptidase M16 family
AVIN_RS18980	COG0535	radical SAM domain protein
AVIN_RS18990	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AVIN_RS18995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVIN_RS19000	COG3284	Transcriptional regulator
AVIN_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS19010	COG3199	ATP-NAD kinase
AVIN_RS19015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVIN_RS19020	COG0022	dehydrogenase e1 component
AVIN_RS19030	COG1063	alcohol dehydrogenase
AVIN_RS19045	COG1509	lysine 2,3-aminomutase activity
AVIN_RS19055	COG2801	Transposase and inactivated derivatives
AVIN_RS19075	COG2814	Major facilitator Superfamily
AVIN_RS19095	COG0659	secondary active sulfate transmembrane transporter activity
AVIN_RS19100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVIN_RS19120	COG3093	addiction module antidote protein HigA
AVIN_RS19135	COG0583	DNA-binding transcription factor activity
AVIN_RS19140	COG3135	benzoate transporter
AVIN_RS19150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVIN_RS19150	COG0543	2 iron, 2 sulfur cluster binding
AVIN_RS19155	COG2814	Major facilitator Superfamily
AVIN_RS19160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS19165	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AVIN_RS19175	COG3971	2-oxopent-4-enoate hydratase activity
AVIN_RS19205	COG3384	dioxygenase
AVIN_RS19255	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AVIN_RS19265	COG1335	isochorismatase
AVIN_RS19275	COG0675	Transposase, IS605 OrfB family
AVIN_RS19285	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AVIN_RS19310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVIN_RS19315	COG3008	intermembrane lipid transfer
AVIN_RS19320	COG2995	paraquat-inducible protein a
AVIN_RS19325	COG2995	paraquat-inducible protein a
AVIN_RS19355	COG1183	phosphatidylcholine synthase activity
AVIN_RS19360	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVIN_RS19370	COG0028	Belongs to the TPP enzyme family
AVIN_RS19380	COG3098	single-species biofilm formation
AVIN_RS19390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVIN_RS19410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVIN_RS19420	COG1489	DNA binding
AVIN_RS19425	COG0436	Aminotransferase
AVIN_RS19430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVIN_RS19435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVIN_RS19445	COG3852	Histidine kinase
AVIN_RS19455	COG0617	tRNA 3'-terminal CCA addition
AVIN_RS19470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVIN_RS19475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AVIN_RS19480	COG0166	Belongs to the GPI family
AVIN_RS19500	COG1185	polyribonucleotide nucleotidyltransferase activity
AVIN_RS19505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVIN_RS19515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVIN_RS19520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVIN_RS19525	COG0195	Participates in both transcription termination and antitermination
AVIN_RS19530	COG0779	Required for maturation of 30S ribosomal subunits
AVIN_RS19545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVIN_RS19550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVIN_RS19555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVIN_RS19560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVIN_RS19565	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVIN_RS19590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVIN_RS19595	COG0484	heat shock protein binding
AVIN_RS19600	COG0443	Heat shock 70 kDa protein
AVIN_RS19605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVIN_RS19610	COG0497	DNA recombination
AVIN_RS19620	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVIN_RS19625	COG2914	Belongs to the UPF0125 (RnfH) family
AVIN_RS19635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVIN_RS19640	COG2186	Transcriptional regulator
AVIN_RS19645	COG1620	l-lactate permease
AVIN_RS19650	COG0247	lactate metabolic process
AVIN_RS19655	COG1139	Iron-sulfur cluster binding protein
AVIN_RS19670	COG2205	protein histidine kinase activity
AVIN_RS19705	COG0528	UMP kinase activity
AVIN_RS19710	COG0528	UMP kinase activity
AVIN_RS19715	COG3960	tartronate-semialdehyde synthase activity
AVIN_RS19720	COG0583	DNA-binding transcription factor activity
AVIN_RS19725	COG0281	malic enzyme
AVIN_RS19730	COG1620	l-lactate permease
AVIN_RS19735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVIN_RS19740	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AVIN_RS19745	COG0247	lactate metabolic process
AVIN_RS19750	COG0277	FAD linked oxidase domain protein
AVIN_RS19755	COG0277	FAD linked oxidase domain protein
AVIN_RS19760	COG2186	Transcriptional regulator
AVIN_RS19765	COG0148	phosphopyruvate hydratase activity
AVIN_RS19775	COG3835	regulator
AVIN_RS19780	COG1929	Belongs to the glycerate kinase type-1 family
AVIN_RS19785	COG3960	tartronate-semialdehyde synthase activity
AVIN_RS19790	COG3622	Belongs to the hyi family
AVIN_RS19795	COG2084	Dehydrogenase
AVIN_RS19800	COG1741	Belongs to the pirin family
AVIN_RS19825	COG3150	esterase
AVIN_RS19830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVIN_RS19840	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVIN_RS19880	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVIN_RS19885	COG1129	ABC transporter
AVIN_RS19900	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS19910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS19920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVIN_RS19920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVIN_RS19985	COG0626	cystathionine gamma-synthase activity
AVIN_RS19995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS20005	COG3829	transcription factor binding
AVIN_RS20020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS20030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVIN_RS20075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVIN_RS20090	COG2995	paraquat-inducible protein a
AVIN_RS20095	COG2995	paraquat-inducible protein a
AVIN_RS20100	COG3008	intermembrane lipid transfer
AVIN_RS20100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVIN_RS20105	COG2963	transposase activity
AVIN_RS20125	COG1595	DNA-templated transcription, initiation
AVIN_RS20135	COG0628	permease
AVIN_RS20165	COG1132	(ABC) transporter
AVIN_RS20170	COG0156	8-amino-7-oxononanoate synthase activity
AVIN_RS20175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVIN_RS20190	COG0456	acetyltransferase
AVIN_RS20200	COG1213	nucleotidyl transferase
AVIN_RS20215	COG1183	phosphatidylcholine synthase activity
AVIN_RS20265	COG0463	Glycosyl transferase, family 2
AVIN_RS20265	COG1216	Glycosyl transferase, family 2
AVIN_RS20285	COG0583	DNA-binding transcription factor activity
AVIN_RS20300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVIN_RS20320	COG0494	nUDIX hydrolase
AVIN_RS20330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVIN_RS20335	COG1519	Transferase
AVIN_RS20345	COG0667	Aldo Keto reductase
AVIN_RS20370	COG2755	lipolytic protein G-D-S-L family
AVIN_RS20370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVIN_RS20375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVIN_RS20375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVIN_RS20390	COG1132	(ABC) transporter
AVIN_RS20405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVIN_RS20410	COG1442	glycosyl transferase family 8
AVIN_RS20425	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS20430	COG2192	nodulation
AVIN_RS20450	COG0438	transferase activity, transferring glycosyl groups
AVIN_RS20455	COG0859	PFAM glycosyl transferase family 9
AVIN_RS20460	COG0859	PFAM glycosyl transferase family 9
AVIN_RS20495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVIN_RS20515	COG2026	Addiction module toxin, RelE StbE family
AVIN_RS20535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVIN_RS20540	COG0583	DNA-binding transcription factor activity
AVIN_RS20550	COG1942	4-Oxalocrotonate Tautomerase
AVIN_RS20555	COG3263	regulation of cellular component size
AVIN_RS20560	COG1196	nuclear chromosome segregation
AVIN_RS20560	COG3264	Mechanosensitive ion channel
AVIN_RS20565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVIN_RS20575	COG0730	response to heat
AVIN_RS20580	COG3118	belongs to the thioredoxin family
AVIN_RS20590	COG1192	Involved in chromosome partitioning
AVIN_RS20595	COG0583	DNA-binding transcription factor activity
AVIN_RS20600	COG2814	Major facilitator Superfamily
AVIN_RS20605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVIN_RS20610	COG0493	'glutamate synthase
AVIN_RS20615	COG0070	glutamate synthase
AVIN_RS20615	COG0067	glutamate synthase
AVIN_RS20615	COG0069	glutamate synthase activity
AVIN_RS20625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVIN_RS20630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVIN_RS20670	COG0281	malic enzyme
AVIN_RS20675	COG0254	rRNA binding
AVIN_RS20680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVIN_RS20685	COG0018	arginyl-trna synthetase
AVIN_RS20695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVIN_RS20700	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVIN_RS20710	COG2226	methyltransferase
AVIN_RS20720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVIN_RS20725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVIN_RS20730	COG0140	phosphoribosyl-ATP diphosphatase activity
AVIN_RS20735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVIN_RS20740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVIN_RS20780	COG1490	D-aminoacyl-tRNA deacylase activity
AVIN_RS20795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVIN_RS20820	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AVIN_RS20825	COG0058	SHG alpha-glucan phosphorylase activity
AVIN_RS20855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVIN_RS20875	COG0148	phosphopyruvate hydratase activity
AVIN_RS20880	COG0149	triose-phosphate isomerase activity
AVIN_RS20905	COG3344	reverse transcriptase
AVIN_RS20910	COG1217	gtp-binding protein TYPA
AVIN_RS20915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVIN_RS20915	COG0301	tRNA thio-modification
AVIN_RS20935	COG3852	Histidine kinase
AVIN_RS20945	COG0450	alkyl hydroperoxide reductase
AVIN_RS20950	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS20960	COG0778	Nitroreductase
AVIN_RS20965	COG0716	FMN binding
AVIN_RS21000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVIN_RS21005	COG0739	heme binding
AVIN_RS21010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVIN_RS21015	COG3344	reverse transcriptase
AVIN_RS21020	COG0316	Belongs to the HesB IscA family
AVIN_RS21025	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVIN_RS21030	COG1981	membrane
AVIN_RS21035	COG0537	adenosine 5'-monophosphoramidase activity
AVIN_RS21040	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AVIN_RS21045	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AVIN_RS21050	COG1765	OsmC-like protein
AVIN_RS21060	COG0134	indole-3-glycerol-phosphate synthase activity
AVIN_RS21065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVIN_RS21070	COG0512	Glutamine amidotransferase of anthranilate synthase
AVIN_RS21080	COG0586	Pfam SNARE associated Golgi protein
AVIN_RS21090	COG0022	dehydrogenase e1 component
AVIN_RS21090	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVIN_RS21095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVIN_RS21105	COG0789	Transcriptional regulator
AVIN_RS21120	COG1335	isochorismatase
AVIN_RS21135	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVIN_RS21145	COG2169	Transcriptional regulator
AVIN_RS21145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVIN_RS21160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVIN_RS21170	COG4935	Belongs to the peptidase S8 family
AVIN_RS21170	COG1404	Belongs to the peptidase S8 family
AVIN_RS21185	COG0477	Major facilitator Superfamily
AVIN_RS21195	COG1538	Outer membrane efflux protein
AVIN_RS21205	COG0384	phenazine biosynthesis protein PhzF
AVIN_RS21215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVIN_RS21230	COG0583	DNA-binding transcription factor activity
AVIN_RS21305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVIN_RS21310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVIN_RS21315	COG0583	DNA-binding transcription factor activity
AVIN_RS21325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVIN_RS21330	COG0477	Major facilitator Superfamily
AVIN_RS21345	COG1028	Short-chain dehydrogenase reductase Sdr
AVIN_RS21350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVIN_RS21355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVIN_RS21365	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVIN_RS21385	COG2967	ApaG domain
AVIN_RS21390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVIN_RS21395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVIN_RS21400	COG2766	serine protein kinase
AVIN_RS21405	COG2718	Belongs to the UPF0229 family
AVIN_RS21410	COG2719	SpoVR family
AVIN_RS21415	COG0617	tRNA 3'-terminal CCA addition
AVIN_RS21430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVIN_RS21440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVIN_RS21445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVIN_RS21450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVIN_RS21460	COG0358	DNA primase activity
AVIN_RS21465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVIN_RS21470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVIN_RS21490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AVIN_RS21505	COG1058	Belongs to the CinA family
AVIN_RS21505	COG1546	Belongs to the CinA family
AVIN_RS21510	COG3546	catalase activity
AVIN_RS21545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVIN_RS21550	COG1120	ATPase activity
AVIN_RS21555	COG1595	DNA-templated transcription, initiation
AVIN_RS21560	COG3712	iron ion homeostasis
AVIN_RS21565	COG4772	TonB-dependent receptor
AVIN_RS21575	COG2267	carboxylic ester hydrolase activity
AVIN_RS21600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVIN_RS21600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVIN_RS21615	COG1178	ABC-type Fe3 transport system permease component
AVIN_RS21625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVIN_RS21630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVIN_RS21635	COG0006	proline dipeptidase activity
AVIN_RS21640	COG3079	Belongs to the UPF0149 family
AVIN_RS21655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVIN_RS21670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVIN_RS21685	COG0248	Ppx GppA phosphatase
AVIN_RS21690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVIN_RS21700	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVIN_RS21705	COG1671	Belongs to the UPF0178 family
AVIN_RS21720	COG0861	Integral membrane protein TerC family
AVIN_RS21725	COG0488	(ABC) transporter
AVIN_RS21775	COG0165	Argininosuccinate lyase
AVIN_RS21795	COG1965	Belongs to the frataxin family
AVIN_RS21810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVIN_RS21820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVIN_RS21840	COG0432	Pfam Uncharacterised protein family UPF0047
AVIN_RS21845	COG0004	ammonium transporteR
AVIN_RS21850	COG0347	Belongs to the P(II) protein family
AVIN_RS21855	COG2960	long-chain fatty acid transporting porin activity
AVIN_RS21860	COG0606	chelatase, subunit chli
AVIN_RS21870	COG0583	DNA-binding transcription factor activity
AVIN_RS21880	COG1741	Belongs to the pirin family
AVIN_RS21915	COG0753	catalase activity
AVIN_RS21920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVIN_RS21945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVIN_RS21955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVIN_RS21965	COG1012	belongs to the aldehyde dehydrogenase family
AVIN_RS21970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVIN_RS21975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVIN_RS21980	COG0747	negative chemotaxis
AVIN_RS21990	COG2177	Part of the ABC transporter FtsEX involved in
AVIN_RS21995	COG2884	Cell division ATP-binding protein ftsE
AVIN_RS22000	COG0552	protein localization to endoplasmic reticulum
AVIN_RS22010	COG0584	glycerophosphoryl diester phosphodiesterase
AVIN_RS22020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVIN_RS22025	COG0697	spore germination
AVIN_RS22030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVIN_RS22035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVIN_RS22040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVIN_RS22045	COG0730	response to heat
AVIN_RS22060	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AVIN_RS22065	COG0494	nUDIX hydrolase
AVIN_RS22080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVIN_RS22085	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVIN_RS22095	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVIN_RS22100	COG0277	FAD linked oxidase domain protein
AVIN_RS22105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVIN_RS22110	COG0679	Auxin Efflux Carrier
AVIN_RS22115	COG3180	Ammonia monooxygenase
AVIN_RS22150	COG0583	DNA-binding transcription factor activity
AVIN_RS22155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVIN_RS22185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVIN_RS22200	COG1253	flavin adenine dinucleotide binding
AVIN_RS22205	COG0739	heme binding
AVIN_RS22220	COG0581	inorganic phosphate transmembrane transporter activity
AVIN_RS22225	COG0573	inorganic phosphate transmembrane transporter activity
AVIN_RS22235	COG1607	acyl-coa hydrolase
AVIN_RS22240	COG0676	glucose-6-phosphate 1-epimerase activity
AVIN_RS22275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVIN_RS22295	COG1177	transmembrane transport
AVIN_RS22300	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVIN_RS22305	COG3842	ATPase activity
AVIN_RS22320	COG3547	Transposase (IS116 IS110 IS902 family)
AVIN_RS22325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AVIN_RS22335	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AVIN_RS22345	COG0174	glutamine synthetase
AVIN_RS22350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVIN_RS22355	COG0174	glutamine synthetase
AVIN_RS22365	COG2957	Belongs to the agmatine deiminase family
AVIN_RS22370	COG0640	Transcriptional regulator
AVIN_RS22380	COG3706	GGDEF domain
AVIN_RS22450	COG3909	cytochrome
AVIN_RS22465	COG0667	Aldo Keto reductase
AVIN_RS22495	COG0596	Alpha beta hydrolase
AVIN_RS22535	COG1012	belongs to the aldehyde dehydrogenase family
AVIN_RS22550	COG0165	Argininosuccinate lyase
AVIN_RS22555	COG1301	dicarboxylic acid transport
AVIN_RS22560	COG0583	DNA-binding transcription factor activity
AVIN_RS22630	COG3180	Ammonia monooxygenase
AVIN_RS22645	COG1024	Enoyl-CoA hydratase
AVIN_RS22650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVIN_RS22655	COG1960	acyl-CoA dehydrogenase activity
AVIN_RS22660	COG0789	Transcriptional regulator
AVIN_RS22670	COG2851	Citrate transporter
AVIN_RS22675	COG0861	Integral membrane protein TerC family
AVIN_RS22805	COG3293	Transposase
AVIN_RS22820	COG0679	Auxin Efflux Carrier
AVIN_RS22825	COG0149	triose-phosphate isomerase activity
AVIN_RS22840	COG0697	spore germination
AVIN_RS22850	COG0149	triose-phosphate isomerase activity
AVIN_RS22855	COG0148	phosphopyruvate hydratase activity
AVIN_RS22880	COG3718	enzyme involved in inositol metabolism
AVIN_RS22885	COG0477	Major facilitator Superfamily
AVIN_RS22885	COG2814	Major facilitator Superfamily
AVIN_RS22900	COG3962	Belongs to the TPP enzyme family
AVIN_RS22905	COG0673	inositol 2-dehydrogenase activity
AVIN_RS22910	COG1082	Xylose isomerase domain protein TIM barrel
AVIN_RS22915	COG1879	ABC-type sugar transport system periplasmic component
AVIN_RS22950	COG0625	glutathione transferase activity
AVIN_RS22960	COG1609	Transcriptional regulator
AVIN_RS22980	COG0673	inositol 2-dehydrogenase activity
AVIN_RS22985	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS22995	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVIN_RS23000	COG1129	ABC transporter
AVIN_RS23010	COG1120	ATPase activity
AVIN_RS23015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVIN_RS23135	COG3415	Transposase
AVIN_RS23135	COG2801	Transposase and inactivated derivatives
AVIN_RS23145	COG0784	Response regulator, receiver
AVIN_RS23145	COG5002	protein histidine kinase activity
AVIN_RS23145	COG2205	protein histidine kinase activity
AVIN_RS23150	COG3437	response regulator, receiver
AVIN_RS23190	COG4149	molybdate abc transporter
AVIN_RS23290	COG2914	Belongs to the UPF0125 (RnfH) family
AVIN_RS23295	COG4660	Part of a membrane complex involved in electron transport
AVIN_RS23310	COG4656	Part of a membrane complex involved in electron transport
AVIN_RS23315	COG2878	Part of a membrane complex involved in electron transport
AVIN_RS23320	COG4657	Part of a membrane complex involved in electron transport
AVIN_RS23360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVIN_RS23370	COG3604	Transcriptional regulator
AVIN_RS23380	COG0517	IMP dehydrogenase activity
AVIN_RS23380	COG1125	glycine betaine transport
AVIN_RS23385	COG2116	formate transmembrane transporter activity
AVIN_RS23390	COG2271	Major facilitator Superfamily
AVIN_RS23440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVIN_RS23450	COG2271	Major facilitator Superfamily
AVIN_RS23455	COG4948	Mandelate Racemase Muconate Lactonizing
AVIN_RS23460	COG0800	Aldolase
AVIN_RS23470	COG1414	Transcriptional regulator
AVIN_RS23480	COG4580	involved in the transport of maltose and maltodextrins
AVIN_RS23485	COG2207	Transcriptional regulator
AVIN_RS23495	COG1486	melibiose metabolic process
AVIN_RS23500	COG2211	Major facilitator Superfamily
AVIN_RS23510	COG3386	PFAM SMP-30 Gluconolaconase
AVIN_RS23520	COG0366	Alpha amylase catalytic
AVIN_RS23525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVIN_RS23540	COG0667	Aldo Keto reductase
AVIN_RS23555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVIN_RS23560	COG1538	Outer membrane efflux protein
AVIN_RS23565	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVIN_RS23580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVIN_RS23610	COG0840	transmembrane signaling receptor activity
AVIN_RS23620	COG2852	Protein conserved in bacteria
AVIN_RS23625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVIN_RS23630	COG1074	ATP-dependent DNA helicase activity
AVIN_RS23635	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AVIN_RS23650	COG1272	protein, Hemolysin III
AVIN_RS23655	COG1082	Xylose isomerase domain protein TIM barrel
AVIN_RS23700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVIN_RS23705	COG1349	DNA-binding transcription factor activity
AVIN_RS23715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVIN_RS23730	COG0601	transmembrane transport
AVIN_RS23735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVIN_RS23740	COG4172	Belongs to the ABC transporter superfamily
AVIN_RS23765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVIN_RS23805	COG4771	TonB-dependent receptor
AVIN_RS23820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVIN_RS23825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVIN_RS23830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVIN_RS23835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVIN_RS23840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVIN_RS23845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVIN_RS23855	COG0356	it plays a direct role in the translocation of protons across the membrane
AVIN_RS23860	COG3312	ion transport
AVIN_RS23865	COG1475	DNA binding
AVIN_RS23870	COG1192	Involved in chromosome partitioning
AVIN_RS23875	COG0357	Ribosomal RNA small subunit methyltransferase G
AVIN_RS23880	COG0445	tRNA wobble uridine modification
AVIN_RS23910	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AVIN_RS23930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AVIN_RS23955	COG0706	membrane insertase activity
AVIN_RS23960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVIN_RS23965	COG0594	ribonuclease P activity
AVIN_RS23970	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVIN_RS23990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVIN_RS24070	COG0583	DNA-binding transcription factor activity