locus-tag	class	description
GB849_RS00010	COG0592	DNA-directed DNA polymerase activity
GB849_RS00015	COG2501	S4 domain
GB849_RS00025	COG0187	DNA topoisomerase II activity
GB849_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GB849_RS00065	COG0516	GMP reductase activity
GB849_RS00065	COG0517	IMP dehydrogenase activity
GB849_RS00070	COG1686	Belongs to the peptidase S11 family
GB849_RS00100	COG1428	Deoxynucleoside kinase
GB849_RS00105	COG1428	Deoxynucleoside kinase
GB849_RS00110	COG1335	isochorismatase
GB849_RS00115	COG0590	tRNA wobble adenosine to inosine editing
GB849_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GB849_RS00180	COG1982	Orn Lys Arg decarboxylase major
GB849_RS00190	COG0470	DNA polymerase III
GB849_RS00195	COG1774	PSP1 C-terminal conserved region
GB849_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GB849_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GB849_RS00220	COG2002	toxin-antitoxin pair type II binding
GB849_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GB849_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GB849_RS00230	COG0084	hydrolase, TatD family'
GB849_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GB849_RS00250	COG4466	Protein conserved in bacteria
GB849_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GB849_RS00270	COG0251	oxidation-reduction process
GB849_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GB849_RS00305	COG2002	toxin-antitoxin pair type II binding
GB849_RS00310	COG2244	polysaccharide biosynthetic process
GB849_RS00315	COG3956	TIGRFAM MazG family protein
GB849_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GB849_RS00340	COG1098	S1 RNA binding domain
GB849_RS00355	COG2208	phosphoserine phosphatase activity
GB849_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GB849_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GB849_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GB849_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GB849_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GB849_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GB849_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GB849_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GB849_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GB849_RS00420	COG1396	sequence-specific DNA binding
GB849_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GB849_RS00515	COG3880	PFAM UvrB UvrC protein
GB849_RS00525	COG0542	response to heat
GB849_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GB849_RS00560	COG1045	serine acetyltransferase
GB849_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GB849_RS00580	COG3688	RNA-binding protein containing a PIN domain
GB849_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GB849_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
GB849_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GB849_RS00625	COG2813	Specifically methylates the guanine in position
GB849_RS00640	COG1358	cellular component organization or biogenesis
GB849_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
GB849_RS00770	COG0201	protein transport
GB849_RS00780	COG0024	Methionine aminopeptidase
GB849_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GB849_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GB849_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GB849_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
GB849_RS00855	COG0489	protein tyrosine kinase activity
GB849_RS00865	COG2194	sulfuric ester hydrolase activity
GB849_RS00870	COG0726	polysaccharide deacetylase
GB849_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GB849_RS00955	COG4856	YbbR-like protein
GB849_RS00975	COG0596	Alpha beta hydrolase
GB849_RS00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GB849_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS01035	COG2011	ABC-type metal ion transport system permease component
GB849_RS01045	COG1464	Belongs to the NlpA lipoprotein family
GB849_RS01050	COG0604	alcohol dehydrogenase
GB849_RS01060	COG0277	FAD linked oxidase domain protein
GB849_RS01065	COG2271	Major facilitator Superfamily
GB849_RS01075	COG2814	Major facilitator Superfamily
GB849_RS01090	COG0601	transmembrane transport
GB849_RS01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GB849_RS01100	COG0444	Belongs to the ABC transporter superfamily
GB849_RS01105	COG4608	Belongs to the ABC transporter superfamily
GB849_RS01125	COG4166	transmembrane transport
GB849_RS01130	COG4166	transmembrane transport
GB849_RS01135	COG0656	L-ascorbic acid biosynthetic process
GB849_RS01155	COG4149	molybdate abc transporter
GB849_RS01160	COG0725	ABC transporter, periplasmic molybdate-binding protein
GB849_RS01165	COG1910	domain protein
GB849_RS01180	COG0697	spore germination
GB849_RS01195	COG0204	Acyl-transferase
GB849_RS01205	COG1609	Transcriptional regulator
GB849_RS01215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS01235	COG0084	hydrolase, TatD family'
GB849_RS01260	COG0488	(ABC) transporter
GB849_RS01270	COG0747	negative chemotaxis
GB849_RS01275	COG0747	negative chemotaxis
GB849_RS01280	COG0601	transmembrane transport
GB849_RS01285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GB849_RS01290	COG0444	Belongs to the ABC transporter superfamily
GB849_RS01295	COG4608	Belongs to the ABC transporter superfamily
GB849_RS01300	COG0561	phosphatase activity
GB849_RS01330	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GB849_RS01335	COG0179	Fumarylacetoacetate (FAA) hydrolase
GB849_RS01345	COG0531	amino acid
GB849_RS01350	COG2814	Major facilitator Superfamily
GB849_RS01360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GB849_RS01370	COG4294	response to UV
GB849_RS01375	COG0705	Rhomboid family
GB849_RS01385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GB849_RS01390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GB849_RS01395	COG0864	Transcriptional regulator
GB849_RS01400	COG2337	Toxic component of a toxin-antitoxin (TA) module
GB849_RS01405	COG2183	response to ionizing radiation
GB849_RS01500	COG0802	atpase or kinase
GB849_RS01505	COG1214	PFAM Peptidase M22, glycoprotease
GB849_RS01510	COG0456	acetyltransferase
GB849_RS01520	COG0488	(ABC) transporter
GB849_RS01535	COG1266	CAAX protease self-immunity
GB849_RS01555	COG2252	PERMEase
GB849_RS01565	COG5002	protein histidine kinase activity
GB849_RS01590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GB849_RS01620	COG2226	methyltransferase
GB849_RS01640	COG1215	transferase activity, transferring glycosyl groups
GB849_RS01660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS01665	COG0506	proline dehydrogenase activity
GB849_RS01690	COG0697	spore germination
GB849_RS01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GB849_RS01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GB849_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GB849_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GB849_RS01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GB849_RS01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GB849_RS01775	COG0151	Belongs to the GarS family
GB849_RS01800	COG0210	DNA helicase
GB849_RS01810	COG4851	CamS sex pheromone cAM373 precursor
GB849_RS01825	COG1335	isochorismatase
GB849_RS01855	COG0003	Pfam Anion-transporting ATPase
GB849_RS01860	COG1846	Transcriptional regulator
GB849_RS01865	COG4682	membrane
GB849_RS01885	COG1597	lipid kinase activity
GB849_RS01890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GB849_RS01895	COG0546	phosphoglycolate phosphatase activity
GB849_RS01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GB849_RS01910	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS01915	COG2076	Multidrug Resistance protein
GB849_RS01920	COG2309	aminopeptidase activity
GB849_RS01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GB849_RS01950	COG0028	Belongs to the TPP enzyme family
GB849_RS01965	COG4807	Protein conserved in bacteria
GB849_RS01990	COG0673	inositol 2-dehydrogenase activity
GB849_RS01995	COG0277	FAD linked oxidase domain protein
GB849_RS02005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GB849_RS02025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GB849_RS02030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GB849_RS02040	COG2814	Major facilitator Superfamily
GB849_RS02060	COG4807	Protein conserved in bacteria
GB849_RS02085	COG1757	Na H antiporter
GB849_RS02090	COG1473	amidohydrolase
GB849_RS02105	COG0450	alkyl hydroperoxide reductase
GB849_RS02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS02145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS02160	COG0166	Belongs to the GPI family
GB849_RS02200	COG3541	Predicted nucleotidyltransferase
GB849_RS02205	COG2814	Major facilitator Superfamily
GB849_RS02210	COG0723	plastoquinol--plastocyanin reductase activity
GB849_RS02210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GB849_RS02235	COG0765	amino acid transport
GB849_RS02240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS02250	COG0840	transmembrane signaling receptor activity
GB849_RS02255	COG0366	Alpha amylase catalytic
GB849_RS02260	COG1263	PTS System
GB849_RS02260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS02260	COG2190	(PTS) system
GB849_RS02280	COG1695	Transcriptional regulator
GB849_RS02285	COG0577	efflux transmembrane transporter activity
GB849_RS02290	COG1136	(ABC) transporter
GB849_RS02315	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GB849_RS02345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GB849_RS02360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GB849_RS02370	COG1116	anion transmembrane transporter activity
GB849_RS02380	COG0488	(ABC) transporter
GB849_RS02430	COG2270	Major facilitator Superfamily
GB849_RS02460	COG2310	stress, protein
GB849_RS02465	COG2310	stress, protein
GB849_RS02470	COG2310	stress, protein
GB849_RS02475	COG0861	Integral membrane protein TerC family
GB849_RS02485	COG3853	Toxic anion resistance protein (TelA)
GB849_RS02500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GB849_RS02510	COG1295	ribonuclease BN
GB849_RS02515	COG2217	Heavy metal translocating P-type atpase
GB849_RS02520	COG0697	spore germination
GB849_RS02535	COG0681	Belongs to the peptidase S26 family
GB849_RS02545	COG0586	Pfam SNARE associated Golgi protein
GB849_RS02560	COG3871	stress protein (general stress protein 26)
GB849_RS02565	COG0387	Pfam Sodium calcium exchanger
GB849_RS02575	COG0535	radical SAM domain protein
GB849_RS02595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GB849_RS02615	COG3829	transcription factor binding
GB849_RS02625	COG0833	amino acid
GB849_RS02630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GB849_RS02660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS02660	COG1263	PTS System
GB849_RS02665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GB849_RS02680	COG0463	Glycosyl transferase, family 2
GB849_RS02690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GB849_RS02690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GB849_RS02710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GB849_RS02730	COG0402	S-adenosylhomocysteine deaminase activity
GB849_RS02735	COG1090	epimerase
GB849_RS02765	COG1988	membrane-bound metal-dependent
GB849_RS02770	COG1194	a g-specific adenine glycosylase
GB849_RS02795	COG1132	(ABC) transporter
GB849_RS02800	COG4129	membrane
GB849_RS02805	COG0070	glutamate synthase
GB849_RS02805	COG0067	glutamate synthase
GB849_RS02805	COG0069	glutamate synthase activity
GB849_RS02815	COG4555	ABC transporter
GB849_RS02835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GB849_RS02840	COG0735	belongs to the Fur family
GB849_RS02950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GB849_RS02970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GB849_RS02980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GB849_RS02990	COG2766	serine protein kinase
GB849_RS03010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GB849_RS03020	COG1585	Membrane protein implicated in regulation of membrane protease activity
GB849_RS03025	COG2268	Band 7 protein
GB849_RS03035	COG3290	protein histidine kinase activity
GB849_RS03040	COG4565	transcriptional regulatory protein
GB849_RS03045	COG2851	Citrate transporter
GB849_RS03070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GB849_RS03075	COG3842	ATPase activity
GB849_RS03080	COG1175	transmembrane transport
GB849_RS03085	COG0395	ABC-type sugar transport system, permease component
GB849_RS03095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GB849_RS03100	COG0745	RESPONSE REGULATOR receiver
GB849_RS03105	COG5002	protein histidine kinase activity
GB849_RS03115	COG4990	cell redox homeostasis
GB849_RS03125	COG0697	spore germination
GB849_RS03130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS03140	COG5002	protein histidine kinase activity
GB849_RS03145	COG0745	RESPONSE REGULATOR receiver
GB849_RS03150	COG0454	-acetyltransferase
GB849_RS03150	COG0456	acetyltransferase
GB849_RS03155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GB849_RS03160	COG3383	formate dehydrogenase (NAD+) activity
GB849_RS03165	COG2427	Protein of unknown function (DUF1641)
GB849_RS03180	COG0531	amino acid
GB849_RS03185	COG0640	Transcriptional regulator
GB849_RS03190	COG2217	Heavy metal translocating P-type atpase
GB849_RS03195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GB849_RS03210	COG3227	Zinc metalloprotease (Elastase)
GB849_RS03230	COG2720	vancomycin resistance protein
GB849_RS03235	COG1316	TRANSCRIPTIONal
GB849_RS03240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS03245	COG0346	lactoylglutathione lyase activity
GB849_RS03250	COG1253	flavin adenine dinucleotide binding
GB849_RS03255	COG1027	Aspartate ammonia-lyase
GB849_RS03265	COG1620	l-lactate permease
GB849_RS03280	COG3104	oligopeptide transport
GB849_RS03285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS03305	COG2226	methyltransferase
GB849_RS03310	COG0156	8-amino-7-oxononanoate synthase activity
GB849_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GB849_RS03320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GB849_RS03330	COG4548	von Willebrand factor, type A
GB849_RS03335	COG0714	Associated with various cellular activities
GB849_RS03340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS03360	COG0531	amino acid
GB849_RS03365	COG2188	Transcriptional regulator
GB849_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS03370	COG1263	PTS System
GB849_RS03375	COG0366	Alpha amylase catalytic
GB849_RS03390	COG0697	spore germination
GB849_RS03395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GB849_RS03400	COG1115	amino acid carrier protein
GB849_RS03405	COG1126	abc transporter atp-binding protein
GB849_RS03410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS03415	COG0765	amino acid transport
GB849_RS03420	COG0765	amino acid transport
GB849_RS03425	COG0833	amino acid
GB849_RS03440	COG1595	DNA-templated transcription, initiation
GB849_RS03450	COG2378	regulation of single-species biofilm formation
GB849_RS03455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GB849_RS03460	COG5002	protein histidine kinase activity
GB849_RS03475	COG0659	secondary active sulfate transmembrane transporter activity
GB849_RS03490	COG0747	negative chemotaxis
GB849_RS03500	COG0601	transmembrane transport
GB849_RS03505	COG4608	Belongs to the ABC transporter superfamily
GB849_RS03515	COG2271	Major facilitator Superfamily
GB849_RS03520	COG1846	Transcriptional regulator
GB849_RS03525	COG0477	Major facilitator Superfamily
GB849_RS03530	COG1609	Transcriptional regulator
GB849_RS03535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GB849_RS03550	COG1172	Belongs to the binding-protein-dependent transport system permease family
GB849_RS03575	COG1063	alcohol dehydrogenase
GB849_RS03590	COG3568	Endonuclease Exonuclease Phosphatase
GB849_RS03620	COG0840	transmembrane signaling receptor activity
GB849_RS03625	COG3583	domain protein
GB849_RS03625	COG3584	3D domain protein
GB849_RS03630	COG1476	TRANSCRIPTIONal
GB849_RS03650	COG3104	oligopeptide transport
GB849_RS03655	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS03670	COG1113	amino acid transport
GB849_RS03675	COG2252	PERMEase
GB849_RS03690	COG2153	protein acetylation
GB849_RS03700	COG0569	domain protein
GB849_RS03700	COG0475	glutathione-regulated potassium exporter activity
GB849_RS03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GB849_RS03730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GB849_RS03735	COG0833	amino acid
GB849_RS03740	COG4990	cell redox homeostasis
GB849_RS03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GB849_RS03760	COG0697	spore germination
GB849_RS03775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GB849_RS03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GB849_RS03785	COG1918	ferrous iron import across plasma membrane
GB849_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GB849_RS03790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GB849_RS03795	COG0573	inorganic phosphate transmembrane transporter activity
GB849_RS03800	COG0581	inorganic phosphate transmembrane transporter activity
GB849_RS03805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GB849_RS03925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GB849_RS03945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GB849_RS03950	COG1116	anion transmembrane transporter activity
GB849_RS03955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GB849_RS03960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GB849_RS03965	COG0352	thiamine-phosphate diphosphorylase activity
GB849_RS03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GB849_RS03975	COG2104	thiamine diphosphate biosynthetic process
GB849_RS03985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GB849_RS03990	COG0351	phosphomethylpyrimidine kinase
GB849_RS04030	COG2205	protein histidine kinase activity
GB849_RS04035	COG2814	Major facilitator Superfamily
GB849_RS04040	COG1846	Transcriptional regulator
GB849_RS04065	COG1136	(ABC) transporter
GB849_RS04075	COG1172	Belongs to the binding-protein-dependent transport system permease family
GB849_RS04080	COG1129	ABC transporter
GB849_RS04090	COG2252	PERMEase
GB849_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS04110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GB849_RS04115	COG1621	beta-fructofuranosidase activity
GB849_RS04120	COG1263	PTS System
GB849_RS04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS04125	COG1609	Transcriptional regulator
GB849_RS04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS04175	COG0778	Nitroreductase
GB849_RS04180	COG2719	SpoVR family
GB849_RS04185	COG0433	COG0433 Predicted ATPase
GB849_RS04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
GB849_RS04210	COG1937	Protein conserved in bacteria
GB849_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GB849_RS04215	COG0425	Belongs to the sulfur carrier protein TusA family
GB849_RS04220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GB849_RS04225	COG0425	Belongs to the sulfur carrier protein TusA family
GB849_RS04230	COG0425	Belongs to the sulfur carrier protein TusA family
GB849_RS04235	COG0425	Belongs to the sulfur carrier protein TusA family
GB849_RS04235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GB849_RS04245	COG2210	Belongs to the sulfur carrier protein TusA family
GB849_RS04250	COG0730	response to heat
GB849_RS04260	COG1316	TRANSCRIPTIONal
GB849_RS04265	COG0604	alcohol dehydrogenase
GB849_RS04270	COG1283	sodium-dependent phosphate transmembrane transporter activity
GB849_RS04275	COG2814	Major facilitator Superfamily
GB849_RS04285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GB849_RS04285	COG3711	transcriptional antiterminator
GB849_RS04290	COG1447	Phosphotransferase system cellobiose-specific component IIA
GB849_RS04295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GB849_RS04320	COG3584	3D domain protein
GB849_RS04320	COG1388	LysM domain
GB849_RS04325	COG0577	efflux transmembrane transporter activity
GB849_RS04330	COG1136	(ABC) transporter
GB849_RS04340	COG5522	Integral membrane protein (intg_mem_TP0381)
GB849_RS04355	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS04360	COG3546	catalase activity
GB849_RS04395	COG0586	Pfam SNARE associated Golgi protein
GB849_RS04425	COG0531	amino acid
GB849_RS04430	COG0475	glutathione-regulated potassium exporter activity
GB849_RS04440	COG1737	Transcriptional regulator
GB849_RS04450	COG1263	PTS System
GB849_RS04450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS04460	COG2259	Doxx family
GB849_RS04480	COG1522	sequence-specific DNA binding
GB849_RS04495	COG2076	Multidrug Resistance protein
GB849_RS04500	COG1309	transcriptional regulator
GB849_RS04505	COG2814	Major facilitator Superfamily
GB849_RS04510	COG1733	regulation of RNA biosynthetic process
GB849_RS04515	COG1846	Transcriptional regulator
GB849_RS04520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GB849_RS04525	COG0477	Major facilitator Superfamily
GB849_RS04530	COG0657	acetylesterase activity
GB849_RS04535	COG0657	acetylesterase activity
GB849_RS04545	COG2124	cytochrome p450
GB849_RS04555	COG1063	alcohol dehydrogenase
GB849_RS04565	COG1309	transcriptional regulator
GB849_RS04570	COG1683	Conserved Protein
GB849_RS04600	COG1733	regulation of RNA biosynthetic process
GB849_RS04610	COG2249	NAD(P)H dehydrogenase (quinone) activity
GB849_RS04615	COG4533	DNA binding
GB849_RS04620	COG2211	Major facilitator Superfamily
GB849_RS04630	COG0693	protein deglycase activity
GB849_RS04640	COG0531	amino acid
GB849_RS04645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GB849_RS04650	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS04655	COG1132	(ABC) transporter
GB849_RS04660	COG1132	(ABC) transporter
GB849_RS04665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS04670	COG0765	amino acid transport
GB849_RS04675	COG1126	abc transporter atp-binding protein
GB849_RS04690	COG0189	ligase activity
GB849_RS04720	COG0028	Belongs to the TPP enzyme family
GB849_RS04725	COG3527	Alpha-acetolactate decarboxylase
GB849_RS04735	COG0561	phosphatase activity
GB849_RS04740	COG5632	N-Acetylmuramoyl-L-alanine amidase
GB849_RS04740	COG3409	Peptidoglycan-binding domain 1 protein
GB849_RS04745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GB849_RS04765	COG0659	secondary active sulfate transmembrane transporter activity
GB849_RS04780	COG0653	protein targeting
GB849_RS04785	COG2244	polysaccharide biosynthetic process
GB849_RS04795	COG0860	N-Acetylmuramoyl-L-alanine amidase
GB849_RS04800	COG4196	transglutaminase domain protein
GB849_RS04815	COG1696	Membrane protein involved in D-alanine export
GB849_RS04830	COG1024	Enoyl-CoA hydratase
GB849_RS04865	COG1363	Peptidase, m42
GB849_RS04920	COG0477	Major facilitator Superfamily
GB849_RS04925	COG3290	protein histidine kinase activity
GB849_RS04930	COG4565	transcriptional regulatory protein
GB849_RS04935	COG3181	Tripartite tricarboxylate transporter family receptor
GB849_RS05010	COG0789	Transcriptional regulator
GB849_RS05010	COG4978	Transcriptional regulator
GB849_RS05025	COG0305	Participates in initiation and elongation during chromosome replication
GB849_RS05045	COG0477	Major facilitator Superfamily
GB849_RS05115	COG1183	phosphatidylcholine synthase activity
GB849_RS05130	COG2376	Dihydroxyacetone kinase
GB849_RS05140	COG2376	Dihydroxyacetone kinase
GB849_RS05160	COG2770	Histidine kinase
GB849_RS05160	COG3437	response regulator, receiver
GB849_RS05240	COG3237	CsbD-like
GB849_RS05265	COG1191	sigma factor activity
GB849_RS05275	COG2208	phosphoserine phosphatase activity
GB849_RS05280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GB849_RS05285	COG2205	protein histidine kinase activity
GB849_RS05285	COG2198	Histidine kinase
GB849_RS05285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS05285	COG0784	Response regulator, receiver
GB849_RS05345	COG0420	3'-5' exonuclease activity
GB849_RS05350	COG4717	serine-type aminopeptidase activity
GB849_RS05360	COG1309	transcriptional regulator
GB849_RS05365	COG2814	Major facilitator Superfamily
GB849_RS05370	COG0346	lactoylglutathione lyase activity
GB849_RS05375	COG0346	lactoylglutathione lyase activity
GB849_RS05385	COG2267	carboxylic ester hydrolase activity
GB849_RS05415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GB849_RS05420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GB849_RS05430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GB849_RS05440	COG1595	DNA-templated transcription, initiation
GB849_RS05450	COG0772	Belongs to the SEDS family
GB849_RS05460	COG3973	AAA domain
GB849_RS05465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GB849_RS05485	COG4980	gas vesicle protein
GB849_RS05490	COG0537	adenosine 5'-monophosphoramidase activity
GB849_RS05495	COG1131	(ABC) transporter
GB849_RS05500	COG4473	ABC transporter
GB849_RS05515	COG1309	transcriptional regulator
GB849_RS05520	COG3402	PFAM membrane-flanked domain
GB849_RS05525	COG3428	Bacterial PH domain
GB849_RS05560	COG3402	PFAM membrane-flanked domain
GB849_RS05570	COG2329	Antibiotic biosynthesis monooxygenase
GB849_RS05575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GB849_RS05590	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GB849_RS05615	COG1309	transcriptional regulator
GB849_RS05620	COG1511	domain protein
GB849_RS05650	COG2378	regulation of single-species biofilm formation
GB849_RS05655	COG1609	Transcriptional regulator
GB849_RS05665	COG1234	tRNA 3'-trailer cleavage
GB849_RS05670	COG0095	Lipoate-protein ligase
GB849_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
GB849_RS05695	COG3209	COG3209 Rhs family protein
GB849_RS05755	COG1073	alpha beta
GB849_RS05760	COG1408	metallophosphoesterase
GB849_RS05770	COG1078	dGTPase activity
GB849_RS05780	COG1595	DNA-templated transcription, initiation
GB849_RS05785	COG2207	Transcriptional regulator
GB849_RS05785	COG3708	Transcriptional regulator
GB849_RS05795	COG2205	protein histidine kinase activity
GB849_RS05800	COG0745	RESPONSE REGULATOR receiver
GB849_RS05825	COG0501	Belongs to the peptidase M48B family
GB849_RS05830	COG0697	spore germination
GB849_RS05850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GB849_RS05855	COG2224	Isocitrate lyase
GB849_RS05865	COG1278	Cold shock
GB849_RS05880	COG4903	ComK protein
GB849_RS05890	COG0398	Pfam SNARE associated Golgi protein
GB849_RS05950	COG0179	Fumarylacetoacetate (FAA) hydrolase
GB849_RS05975	COG0367	asparagine synthase
GB849_RS05985	COG0753	catalase activity
GB849_RS05990	COG0004	ammonium transporteR
GB849_RS06010	COG2996	Protein conserved in bacteria
GB849_RS06015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GB849_RS06025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS06040	COG0561	phosphatase activity
GB849_RS06060	COG2267	carboxylic ester hydrolase activity
GB849_RS06075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GB849_RS06080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GB849_RS06085	COG5504	Zn-dependent protease
GB849_RS06095	COG0180	Tryptophanyl-tRNA synthetase
GB849_RS06105	COG4166	transmembrane transport
GB849_RS06110	COG0601	transmembrane transport
GB849_RS06115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GB849_RS06120	COG0444	Belongs to the ABC transporter superfamily
GB849_RS06125	COG4608	Belongs to the ABC transporter superfamily
GB849_RS06130	COG0534	Mate efflux family protein
GB849_RS06135	COG4166	transmembrane transport
GB849_RS06150	COG0861	Integral membrane protein TerC family
GB849_RS06155	COG4862	establishment of competence for transformation
GB849_RS06160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS06170	COG1164	Oligoendopeptidase f
GB849_RS06180	COG2346	COG2346, Truncated hemoglobins
GB849_RS06185	COG4116	CYTH
GB849_RS06195	COG2357	RelA SpoT domain protein
GB849_RS06205	COG0564	pseudouridine synthase activity
GB849_RS06220	COG0772	Belongs to the SEDS family
GB849_RS06225	COG0463	Glycosyl transferase, family 2
GB849_RS06225	COG1216	Glycosyl transferase, family 2
GB849_RS06245	COG0457	Tetratricopeptide repeat
GB849_RS06245	COG0463	Glycosyl transferase, family 2
GB849_RS06265	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GB849_RS06280	COG1091	dTDP-4-dehydrorhamnose reductase activity
GB849_RS06325	COG2153	protein acetylation
GB849_RS06335	COG2382	esterase
GB849_RS06350	COG5492	domain, Protein
GB849_RS06355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GB849_RS06365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GB849_RS06365	COG0512	Glutamine amidotransferase of anthranilate synthase
GB849_RS06400	COG1620	l-lactate permease
GB849_RS06405	COG5634	Uncharacterized conserved protein (DUF2278)
GB849_RS06410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS06480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GB849_RS06490	COG1476	TRANSCRIPTIONal
GB849_RS06545	COG1686	Belongs to the peptidase S11 family
GB849_RS06550	COG0681	Belongs to the peptidase S26 family
GB849_RS06585	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS06595	COG1176	ABC-type spermidine putrescine transport system, permease component I
GB849_RS06600	COG1177	transmembrane transport
GB849_RS06605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GB849_RS06615	COG2409	Drug exporters of the RND superfamily
GB849_RS06625	COG0564	pseudouridine synthase activity
GB849_RS06635	COG2340	Cysteine-rich secretory protein family
GB849_RS06640	COG0247	lactate metabolic process
GB849_RS06645	COG0277	FAD linked oxidase domain protein
GB849_RS06650	COG3835	regulator
GB849_RS06660	COG0745	RESPONSE REGULATOR receiver
GB849_RS06665	COG5002	protein histidine kinase activity
GB849_RS06670	COG2186	Transcriptional regulator
GB849_RS06690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GB849_RS06700	COG2116	formate transmembrane transporter activity
GB849_RS06705	COG0861	Integral membrane protein TerC family
GB849_RS06710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GB849_RS06720	COG2030	dehydratase
GB849_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS06745	COG3243	poly(R)-hydroxyalkanoic acid synthase
GB849_RS06755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GB849_RS06765	COG1840	ABC-type Fe3 transport system, periplasmic component
GB849_RS06770	COG3842	ATPase activity
GB849_RS06795	COG1349	DNA-binding transcription factor activity
GB849_RS06805	COG0235	Class ii aldolase
GB849_RS06815	COG2861	carbohydrate metabolic process
GB849_RS06825	COG3852	Histidine kinase
GB849_RS06830	COG1846	Transcriptional regulator
GB849_RS06840	COG2318	DinB family
GB849_RS06845	COG5002	protein histidine kinase activity
GB849_RS06855	COG0720	synthase
GB849_RS06870	COG4873	Protein conserved in bacteria
GB849_RS06900	COG1780	Probably involved in ribonucleotide reductase function
GB849_RS06920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GB849_RS06925	COG1725	Transcriptional regulator
GB849_RS06930	COG1131	(ABC) transporter
GB849_RS06940	COG1131	(ABC) transporter
GB849_RS06945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GB849_RS06950	COG1266	CAAX protease self-immunity
GB849_RS06960	COG1522	sequence-specific DNA binding
GB849_RS06970	COG1335	isochorismatase
GB849_RS06980	COG1619	proteins homologs of microcin C7 resistance protein MccF
GB849_RS06985	COG2070	2-Nitropropane dioxygenase
GB849_RS06990	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GB849_RS07000	COG1696	Membrane protein involved in D-alanine export
GB849_RS07020	COG0716	FMN binding
GB849_RS07030	COG3173	Aminoglycoside phosphotransferase
GB849_RS07045	COG0534	Mate efflux family protein
GB849_RS07065	COG1846	Transcriptional regulator
GB849_RS07075	COG1301	dicarboxylic acid transport
GB849_RS07080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GB849_RS07085	COG4709	membrane
GB849_RS07090	COG3874	Sporulation protein YtfJ
GB849_RS07110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GB849_RS07115	COG0028	Belongs to the TPP enzyme family
GB849_RS07120	COG0440	acetolactate synthase activity
GB849_RS07195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GB849_RS07210	COG1183	phosphatidylcholine synthase activity
GB849_RS07215	COG1368	sulfuric ester hydrolase activity
GB849_RS07225	COG0019	diaminopimelate decarboxylase activity
GB849_RS07245	COG0529	Catalyzes the synthesis of activated sulfate
GB849_RS07250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GB849_RS07270	COG1648	precorrin-2 dehydrogenase activity
GB849_RS07275	COG0733	neurotransmitter:sodium symporter activity
GB849_RS07295	COG1757	Na H antiporter
GB849_RS07310	COG4758	membrane
GB849_RS07315	COG4585	Histidine kinase
GB849_RS07320	COG2197	response regulator
GB849_RS07330	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS07340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GB849_RS07380	COG0730	response to heat
GB849_RS07385	COG0306	phosphate transporter
GB849_RS07390	COG1392	Phosphate transport regulator
GB849_RS07395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GB849_RS07410	COG3852	Histidine kinase
GB849_RS07415	COG1801	Protein of unknown function DUF72
GB849_RS07425	COG0582	viral genome integration into host DNA
GB849_RS07430	COG5002	protein histidine kinase activity
GB849_RS07445	COG0392	lysyltransferase activity
GB849_RS07445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GB849_RS07460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GB849_RS07465	COG1686	Belongs to the peptidase S11 family
GB849_RS07470	COG2715	membrane protein required for spore maturation
GB849_RS07475	COG0700	Nucleoside recognition
GB849_RS07480	COG1187	pseudouridine synthase activity
GB849_RS07490	COG1333	cytochrome c biogenesis protein
GB849_RS07495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GB849_RS07500	COG0745	RESPONSE REGULATOR receiver
GB849_RS07505	COG5002	protein histidine kinase activity
GB849_RS07510	COG2096	Adenosyltransferase
GB849_RS07515	COG4942	peptidase
GB849_RS07525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GB849_RS07530	COG1141	Ferredoxin
GB849_RS07545	COG1266	CAAX protease self-immunity
GB849_RS07555	COG1408	metallophosphoesterase
GB849_RS07565	COG4862	establishment of competence for transformation
GB849_RS07570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GB849_RS07590	COG0492	ferredoxin-NADP+ reductase activity
GB849_RS07660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GB849_RS07675	COG0142	geranyltranstransferase activity
GB849_RS07685	COG0142	geranyltranstransferase activity
GB849_RS07705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GB849_RS07710	COG0457	Tetratricopeptide repeat
GB849_RS07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GB849_RS07735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GB849_RS07735	COG2010	Cytochrome c
GB849_RS07745	COG4347	Protein of unknown function (DUF1405)
GB849_RS07760	COG2738	Putative neutral zinc metallopeptidase
GB849_RS07770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS07775	COG1694	Mazg nucleotide pyrophosphohydrolase
GB849_RS07790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GB849_RS07795	COG0438	transferase activity, transferring glycosyl groups
GB849_RS07830	COG1199	ATP-dependent helicase activity
GB849_RS07830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GB849_RS07850	COG3935	DnaD domain protein
GB849_RS07855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GB849_RS07865	COG4499	WXG100 protein secretion system (Wss), protein YukC
GB849_RS07865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GB849_RS07920	COG0116	Belongs to the methyltransferase superfamily
GB849_RS07930	COG1199	ATP-dependent helicase activity
GB849_RS07935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GB849_RS07945	COG0024	Methionine aminopeptidase
GB849_RS07960	COG2233	PERMEase
GB849_RS07965	COG2311	Membrane
GB849_RS07970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GB849_RS07980	COG0456	acetyltransferase
GB849_RS08015	COG0754	glutathionylspermidine amidase activity
GB849_RS08030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GB849_RS08070	COG0328	RNA-DNA hybrid ribonuclease activity
GB849_RS08105	COG3403	YqcI/YcgG family
GB849_RS08110	COG1280	lysine exporter protein (LysE YggA)
GB849_RS08130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GB849_RS08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GB849_RS08145	COG0475	glutathione-regulated potassium exporter activity
GB849_RS08150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GB849_RS08155	COG4978	Transcriptional regulator
GB849_RS08155	COG0789	Transcriptional regulator
GB849_RS08170	COG2323	membrane
GB849_RS08175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GB849_RS08210	COG2814	Major facilitator Superfamily
GB849_RS08240	COG1923	regulation of RNA biosynthetic process
GB849_RS08250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GB849_RS08255	COG1360	Flagellar Motor Protein
GB849_RS08260	COG2201	protein-glutamate methylesterase activity
GB849_RS08265	COG2198	Histidine kinase
GB849_RS08265	COG0643	Histidine kinase
GB849_RS08270	COG1776	CheC inhibitor of MCP methylation
GB849_RS08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GB849_RS08285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GB849_RS08305	COG1256	bacterial-type flagellum assembly
GB849_RS08310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GB849_RS08315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GB849_RS08330	COG1815	bacterial-type flagellum-dependent cell motility
GB849_RS08335	COG1558	bacterial-type flagellum-dependent cell motility
GB849_RS08345	COG1766	The M ring may be actively involved in energy transduction
GB849_RS08350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GB849_RS08360	COG1157	protein secretion by the type III secretion system
GB849_RS08395	COG0835	chemotaxis
GB849_RS08395	COG0784	Response regulator, receiver
GB849_RS08405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GB849_RS08410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GB849_RS08415	COG0741	lytic transglycosylase activity
GB849_RS08425	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GB849_RS08430	COG1776	CheC inhibitor of MCP methylation
GB849_RS08430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GB849_RS08440	COG1338	Plays a role in the flagellum-specific transport system
GB849_RS08445	COG1987	bacterial-type flagellum assembly
GB849_RS08455	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GB849_RS08460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GB849_RS08465	COG1419	protein localization to endoplasmic reticulum
GB849_RS08470	COG4786	Flagellar basal body rod
GB849_RS08475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GB849_RS08510	COG2329	Antibiotic biosynthesis monooxygenase
GB849_RS08525	COG3764	Sortase (surface protein transpeptidase)
GB849_RS08530	COG3764	Sortase (surface protein transpeptidase)
GB849_RS08555	COG0583	DNA-binding transcription factor activity
GB849_RS08560	COG3842	ATPase activity
GB849_RS08575	COG1234	tRNA 3'-trailer cleavage
GB849_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS08605	COG1686	Belongs to the peptidase S11 family
GB849_RS08615	COG0406	alpha-ribazole phosphatase activity
GB849_RS08635	COG1846	Transcriptional regulator
GB849_RS08645	COG0367	asparagine synthase
GB849_RS08675	COG1802	Transcriptional regulator
GB849_RS08680	COG0697	spore germination
GB849_RS08685	COG1216	Glycosyl transferase, family 2
GB849_RS08685	COG0438	transferase activity, transferring glycosyl groups
GB849_RS08690	COG1757	Na H antiporter
GB849_RS08695	COG0114	fumarate hydratase activity
GB849_RS08715	COG0534	Mate efflux family protein
GB849_RS08720	COG3340	Belongs to the peptidase S51 family
GB849_RS08760	COG2733	membrane
GB849_RS08795	COG1131	(ABC) transporter
GB849_RS08810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS08815	COG0528	UMP kinase activity
GB849_RS08825	COG1027	Aspartate ammonia-lyase
GB849_RS08830	COG0281	malic enzyme
GB849_RS08835	COG4191	Histidine kinase
GB849_RS08840	COG0784	Response regulator, receiver
GB849_RS08845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GB849_RS08900	COG0860	N-Acetylmuramoyl-L-alanine amidase
GB849_RS08910	COG2814	Major facilitator Superfamily
GB849_RS08930	COG1966	Carbon starvation protein
GB849_RS08940	COG1695	Transcriptional regulator
GB849_RS08950	COG0477	Major facilitator Superfamily
GB849_RS08955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GB849_RS08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GB849_RS08970	COG4166	transmembrane transport
GB849_RS08975	COG2223	nitrite transmembrane transporter activity
GB849_RS08980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GB849_RS08995	COG2244	polysaccharide biosynthetic process
GB849_RS09000	COG0733	neurotransmitter:sodium symporter activity
GB849_RS09010	COG5566	PFAM Mor transcription activator
GB849_RS09015	COG2323	membrane
GB849_RS09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GB849_RS09035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GB849_RS09040	COG0028	Belongs to the TPP enzyme family
GB849_RS09045	COG0440	acetolactate synthase activity
GB849_RS09050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GB849_RS09060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GB849_RS09085	COG2814	Major facilitator Superfamily
GB849_RS09090	COG3384	dioxygenase
GB849_RS09100	COG3279	Response regulator of the LytR AlgR family
GB849_RS09105	COG0427	acetyl-CoA hydrolase
GB849_RS09125	COG1073	alpha beta
GB849_RS09130	COG4166	transmembrane transport
GB849_RS09135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS09140	COG0745	RESPONSE REGULATOR receiver
GB849_RS09155	COG1914	H( )-stimulated, divalent metal cation uptake system
GB849_RS09170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GB849_RS09175	COG0531	amino acid
GB849_RS09195	COG0457	Tetratricopeptide repeat
GB849_RS09205	COG2390	Transcriptional regulator
GB849_RS09215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS09220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GB849_RS09230	COG4846	Membrane protein involved in cytochrome C biogenesis
GB849_RS09240	COG0006	proline dipeptidase activity
GB849_RS09255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GB849_RS09275	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS09285	COG2372	response to copper ion
GB849_RS09285	COG1276	copper resistance
GB849_RS09290	COG4549	nuclear export factor GLE1
GB849_RS09295	COG0697	spore germination
GB849_RS09300	COG0583	DNA-binding transcription factor activity
GB849_RS09305	COG1959	2 iron, 2 sulfur cluster binding
GB849_RS09310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GB849_RS09315	COG0778	Nitroreductase
GB849_RS09325	COG0628	permease
GB849_RS09335	COG1231	oxidoreductase activity
GB849_RS09340	COG0523	cobalamin synthesis protein
GB849_RS09350	COG0411	ABC transporter
GB849_RS09370	COG0583	DNA-binding transcription factor activity
GB849_RS09380	COG1942	4-Oxalocrotonate Tautomerase
GB849_RS09400	COG1271	oxidase subunit
GB849_RS09405	COG1294	oxidase, subunit
GB849_RS09410	COG4988	ABC transporter
GB849_RS09415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GB849_RS09475	COG1619	proteins homologs of microcin C7 resistance protein MccF
GB849_RS09480	COG1686	Belongs to the peptidase S11 family
GB849_RS09495	COG1388	LysM domain
GB849_RS09495	COG0791	NLP P60 protein
GB849_RS09505	COG1132	(ABC) transporter
GB849_RS09510	COG0745	RESPONSE REGULATOR receiver
GB849_RS09515	COG5002	protein histidine kinase activity
GB849_RS09525	COG0300	oxidoreductase activity
GB849_RS09530	COG4122	O-methyltransferase activity
GB849_RS09560	COG0460	homoserine dehydrogenase
GB849_RS09585	COG1316	TRANSCRIPTIONal
GB849_RS09590	COG5002	protein histidine kinase activity
GB849_RS09605	COG1285	pathogenesis
GB849_RS09610	COG1247	-acetyltransferase
GB849_RS09620	COG2814	Major facilitator Superfamily
GB849_RS09625	COG1279	arginine transmembrane transporter activity
GB849_RS09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS09640	COG1752	Esterase of the alpha-beta hydrolase superfamily
GB849_RS09675	COG0577	efflux transmembrane transporter activity
GB849_RS09680	COG2002	toxin-antitoxin pair type II binding
GB849_RS09685	COG1404	Belongs to the peptidase S8 family
GB849_RS09690	COG3842	ATPase activity
GB849_RS09695	COG2508	Transcriptional regulator
GB849_RS09710	COG1175	transmembrane transport
GB849_RS09715	COG0395	ABC-type sugar transport system, permease component
GB849_RS09720	COG5426	von Willebrand factor, type A
GB849_RS09725	COG1940	carbohydrate kinase activity
GB849_RS09730	COG2222	sugar isomerase
GB849_RS09740	COG1105	Belongs to the carbohydrate kinase PfkB family
GB849_RS09745	COG3684	Belongs to the aldolase LacD family
GB849_RS09750	COG0366	Alpha amylase catalytic
GB849_RS09755	COG0366	Alpha amylase catalytic
GB849_RS09760	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GB849_RS09765	COG0640	Transcriptional regulator
GB849_RS09770	COG0667	Aldo Keto reductase
GB849_RS09775	COG2814	Major facilitator Superfamily
GB849_RS09800	COG0840	transmembrane signaling receptor activity
GB849_RS09815	COG3949	Membrane
GB849_RS09820	COG0783	Belongs to the Dps family
GB849_RS09835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GB849_RS09845	COG1231	oxidoreductase activity
GB849_RS09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS09855	COG4989	oxidoreductase activity
GB849_RS09860	COG0523	cobalamin synthesis protein
GB849_RS09865	COG0456	acetyltransferase
GB849_RS09870	COG3443	Belongs to the bacterial solute-binding protein 9 family
GB849_RS09870	COG0803	Belongs to the bacterial solute-binding protein 9 family
GB849_RS09875	COG0702	epimerase
GB849_RS09885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GB849_RS09895	COG4166	transmembrane transport
GB849_RS09910	COG0406	alpha-ribazole phosphatase activity
GB849_RS09925	COG1051	belongs to the nudix hydrolase family
GB849_RS09930	COG0586	Pfam SNARE associated Golgi protein
GB849_RS09935	COG2244	polysaccharide biosynthetic process
GB849_RS09945	COG0701	Predicted permease
GB849_RS09950	COG3689	TIGRFAM TIGR03943 family protein
GB849_RS09955	COG1607	acyl-coa hydrolase
GB849_RS09965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS09980	COG0702	epimerase
GB849_RS09985	COG2839	Protein conserved in bacteria
GB849_RS09990	COG1253	flavin adenine dinucleotide binding
GB849_RS10005	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS10010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GB849_RS10030	COG0860	N-Acetylmuramoyl-L-alanine amidase
GB849_RS10040	COG1876	peptidase activity
GB849_RS10050	COG0154	amidase activity
GB849_RS10055	COG2211	Major facilitator Superfamily
GB849_RS10075	COG0561	phosphatase activity
GB849_RS10085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GB849_RS10090	COG4106	trans-aconitate 2-methyltransferase activity
GB849_RS10105	COG1819	glycosyl
GB849_RS10110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS10145	COG0456	acetyltransferase
GB849_RS10170	COG3874	Sporulation protein YtfJ
GB849_RS10195	COG2226	methyltransferase
GB849_RS10215	COG0346	lactoylglutathione lyase activity
GB849_RS10225	COG0604	alcohol dehydrogenase
GB849_RS10230	COG1595	DNA-templated transcription, initiation
GB849_RS10245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GB849_RS10245	COG0426	domain, Protein
GB849_RS10255	COG0386	Belongs to the glutathione peroxidase family
GB849_RS10260	COG1305	Transglutaminase-like
GB849_RS10265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GB849_RS10270	COG0714	Associated with various cellular activities
GB849_RS10275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GB849_RS10280	COG1140	nitrate reductase beta subunit
GB849_RS10285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GB849_RS10290	COG2181	nitrate reductase activity
GB849_RS10295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GB849_RS10300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GB849_RS10305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GB849_RS10310	COG0303	'Molybdopterin
GB849_RS10315	COG0314	molybdopterin synthase activity
GB849_RS10325	COG2223	nitrite transmembrane transporter activity
GB849_RS10345	COG1648	precorrin-2 dehydrogenase activity
GB849_RS10355	COG1587	Uroporphyrinogen-III synthase
GB849_RS10355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GB849_RS10360	COG2146	nitrite reductase [NAD(P)H] activity
GB849_RS10365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GB849_RS10370	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GB849_RS10405	COG2359	stage V sporulation protein S
GB849_RS10425	COG1418	mRNA catabolic process
GB849_RS10430	COG0488	(ABC) transporter
GB849_RS10445	COG0629	single-stranded DNA binding
GB849_RS10460	COG1413	lyase activity
GB849_RS10535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GB849_RS10540	COG0017	Asparaginyl-tRNA synthetase
GB849_RS10545	COG0733	neurotransmitter:sodium symporter activity
GB849_RS10570	COG2610	gluconate transmembrane transporter activity
GB849_RS10575	COG1454	alcohol dehydrogenase
GB849_RS10580	COG1794	racemase activity, acting on amino acids and derivatives
GB849_RS10590	COG0456	acetyltransferase
GB849_RS10595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GB849_RS10605	COG1131	(ABC) transporter
GB849_RS10610	COG4473	ABC transporter
GB849_RS10620	COG0546	phosphoglycolate phosphatase activity
GB849_RS10635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GB849_RS10640	COG3250	beta-galactosidase activity
GB849_RS10655	COG0768	penicillin binding
GB849_RS10665	COG0204	Acyl-transferase
GB849_RS10670	COG1272	protein, Hemolysin III
GB849_RS10680	COG0805	protein transport
GB849_RS10690	COG1307	EDD domain protein, DegV family
GB849_RS10695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GB849_RS10700	COG1999	signal sequence binding
GB849_RS10705	COG0071	Belongs to the small heat shock protein (HSP20) family
GB849_RS10710	COG0367	asparagine synthase
GB849_RS10730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS10735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GB849_RS10750	COG1335	isochorismatase
GB849_RS10755	COG1051	belongs to the nudix hydrolase family
GB849_RS10765	COG0668	transmembrane transport
GB849_RS10770	COG4585	Histidine kinase
GB849_RS10770	COG2203	Gaf domain
GB849_RS10775	COG2197	response regulator
GB849_RS10780	COG1737	Transcriptional regulator
GB849_RS10785	COG1737	Transcriptional regulator
GB849_RS10790	COG1064	alcohol dehydrogenase
GB849_RS10815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GB849_RS10845	COG1125	glycine betaine transport
GB849_RS10845	COG0517	IMP dehydrogenase activity
GB849_RS10850	COG1174	glycine betaine transport
GB849_RS10885	COG1253	flavin adenine dinucleotide binding
GB849_RS10890	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS10895	COG5506	Protein of unknown function (DUF1694)
GB849_RS10910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GB849_RS10915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GB849_RS10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GB849_RS10925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GB849_RS10930	COG0456	acetyltransferase
GB849_RS10935	COG3829	transcription factor binding
GB849_RS10940	COG1509	lysine 2,3-aminomutase activity
GB849_RS10975	COG4991	sh3 domain protein
GB849_RS10975	COG3064	Membrane
GB849_RS10975	COG0515	serine threonine protein kinase
GB849_RS10980	COG4326	sporulation control protein
GB849_RS10985	COG0671	phosphoesterase, PA-phosphatase related
GB849_RS10990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GB849_RS10995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS11005	COG3728	DNA packaging
GB849_RS11005	COG5484	DNA packaging
GB849_RS11035	COG1595	DNA-templated transcription, initiation
GB849_RS11065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GB849_RS11115	COG4499	WXG100 protein secretion system (Wss), protein YukC
GB849_RS11115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GB849_RS11125	COG2814	Major facilitator Superfamily
GB849_RS11130	COG4841	protein insertion into membrane
GB849_RS11135	COG0372	Belongs to the citrate synthase family
GB849_RS11140	COG2079	MmgE PrpD family protein
GB849_RS11145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GB849_RS11150	COG1960	acyl-CoA dehydrogenase activity
GB849_RS11155	COG2084	Dehydrogenase
GB849_RS11165	COG1280	lysine exporter protein (LysE YggA)
GB849_RS11170	COG1024	Enoyl-CoA hydratase
GB849_RS11185	COG0420	3'-5' exonuclease activity
GB849_RS11210	COG2223	nitrite transmembrane transporter activity
GB849_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS11220	COG1169	isochorismate synthase
GB849_RS11225	COG1021	2,3-dihydroxybenzoate-AMP ligase
GB849_RS11230	COG3433	isochorismatase activity
GB849_RS11230	COG1535	isochorismatase
GB849_RS11235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GB849_RS11245	COG2814	Major facilitator Superfamily
GB849_RS11260	COG0776	regulation of translation
GB849_RS11270	COG2318	DinB family
GB849_RS11280	COG1115	amino acid carrier protein
GB849_RS11305	COG2329	Antibiotic biosynthesis monooxygenase
GB849_RS11310	COG1187	pseudouridine synthase activity
GB849_RS11315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GB849_RS11320	COG1136	(ABC) transporter
GB849_RS11330	COG2814	Major facilitator Superfamily
GB849_RS11345	COG0028	Belongs to the TPP enzyme family
GB849_RS11355	COG2226	methyltransferase
GB849_RS11425	COG1247	-acetyltransferase
GB849_RS11455	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GB849_RS11460	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GB849_RS11470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS11480	COG1278	Cold shock
GB849_RS11495	COG0010	Belongs to the arginase family
GB849_RS11500	COG0561	phosphatase activity
GB849_RS11510	COG1846	Transcriptional regulator
GB849_RS11515	COG2814	Major facilitator Superfamily
GB849_RS11520	COG0583	DNA-binding transcription factor activity
GB849_RS11525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GB849_RS11540	COG0583	DNA-binding transcription factor activity
GB849_RS11545	COG2258	MOSC domain
GB849_RS11560	COG1132	(ABC) transporter
GB849_RS11565	COG1132	(ABC) transporter
GB849_RS11585	COG1396	sequence-specific DNA binding
GB849_RS11625	COG1595	DNA-templated transcription, initiation
GB849_RS11645	COG1649	PFAM Uncharacterised BCR, COG1649
GB849_RS11670	COG2971	BadF BadG BcrA BcrD
GB849_RS11680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GB849_RS11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS11740	COG1309	transcriptional regulator
GB849_RS11755	COG1136	(ABC) transporter
GB849_RS11755	COG0577	efflux transmembrane transporter activity
GB849_RS11760	COG0500	methyltransferase
GB849_RS11760	COG3615	Tellurite resistance protein tehB
GB849_RS11770	COG3961	Belongs to the TPP enzyme family
GB849_RS11795	COG2195	Cleaves the N-terminal amino acid of tripeptides
GB849_RS11810	COG1595	DNA-templated transcription, initiation
GB849_RS11820	COG0768	penicillin binding
GB849_RS11825	COG0768	penicillin binding
GB849_RS11830	COG2367	Beta-lactamase
GB849_RS11835	COG1408	metallophosphoesterase
GB849_RS11845	COG1131	(ABC) transporter
GB849_RS11855	COG1309	transcriptional regulator
GB849_RS11870	COG1960	acyl-CoA dehydrogenase activity
GB849_RS11875	COG0439	Biotin carboxylase
GB849_RS11880	COG0511	ligase activity, forming carbon-carbon bonds
GB849_RS11885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GB849_RS11890	COG1024	Enoyl-CoA hydratase
GB849_RS11895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GB849_RS11900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GB849_RS11915	COG0572	uridine kinase
GB849_RS11920	COG2318	DinB family
GB849_RS11925	COG1686	Belongs to the peptidase S11 family
GB849_RS11950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GB849_RS11970	COG3227	Zinc metalloprotease (Elastase)
GB849_RS12005	COG2814	Major facilitator Superfamily
GB849_RS12015	COG2226	methyltransferase
GB849_RS12045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS12060	COG1063	alcohol dehydrogenase
GB849_RS12065	COG2323	membrane
GB849_RS12070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GB849_RS12085	COG3386	PFAM SMP-30 Gluconolaconase
GB849_RS12095	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GB849_RS12100	COG3773	Cell wall hydrolase
GB849_RS12110	COG0745	RESPONSE REGULATOR receiver
GB849_RS12115	COG2205	protein histidine kinase activity
GB849_RS12125	COG0488	(ABC) transporter
GB849_RS12130	COG1136	(ABC) transporter
GB849_RS12135	COG0577	efflux transmembrane transporter activity
GB849_RS12155	COG0460	homoserine dehydrogenase
GB849_RS12160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS12170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GB849_RS12250	COG5444	nuclease activity
GB849_RS12295	COG2124	cytochrome p450
GB849_RS12325	COG0561	phosphatase activity
GB849_RS12330	COG5002	protein histidine kinase activity
GB849_RS12335	COG0768	penicillin binding
GB849_RS12345	COG1794	racemase activity, acting on amino acids and derivatives
GB849_RS12370	COG2205	protein histidine kinase activity
GB849_RS12380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GB849_RS12385	COG0604	alcohol dehydrogenase
GB849_RS12390	COG0671	phosphoesterase, PA-phosphatase related
GB849_RS12395	COG0768	penicillin binding
GB849_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS12465	COG0584	glycerophosphoryl diester phosphodiesterase
GB849_RS12485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS12490	COG0697	spore germination
GB849_RS12500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GB849_RS12515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GB849_RS12520	COG2223	nitrite transmembrane transporter activity
GB849_RS12535	COG2816	NAD+ diphosphatase activity
GB849_RS12540	COG0592	DNA-directed DNA polymerase activity
GB849_RS12545	COG1051	belongs to the nudix hydrolase family
GB849_RS12575	COG3878	Protein conserved in bacteria
GB849_RS12600	COG4667	esterase of the alpha-beta hydrolase superfamily
GB849_RS12640	COG0322	excinuclease ABC activity
GB849_RS12675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GB849_RS12700	COG1011	Hydrolase
GB849_RS12720	COG1523	belongs to the glycosyl hydrolase 13 family
GB849_RS12725	COG3227	Zinc metalloprotease (Elastase)
GB849_RS12735	COG0346	lactoylglutathione lyase activity
GB849_RS12740	COG0201	protein transport
GB849_RS12780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS12795	COG2959	enzyme of heme biosynthesis
GB849_RS12835	COG1309	transcriptional regulator
GB849_RS12865	COG3284	Transcriptional regulator
GB849_RS12880	COG1349	DNA-binding transcription factor activity
GB849_RS12895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GB849_RS12900	COG0508	dehydrogenase complex catalyzes the overall conversion of
GB849_RS12905	COG0022	dehydrogenase e1 component
GB849_RS12910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GB849_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS12935	COG0456	acetyltransferase
GB849_RS12935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GB849_RS12940	COG0572	uridine kinase
GB849_RS12975	COG4176	ABC-type proline glycine betaine transport system permease component
GB849_RS12980	COG0517	IMP dehydrogenase activity
GB849_RS12980	COG4175	Glycine betaine
GB849_RS13005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GB849_RS13010	COG2153	protein acetylation
GB849_RS13015	COG3397	chitin binding
GB849_RS13020	COG1819	glycosyl
GB849_RS13035	COG2205	protein histidine kinase activity
GB849_RS13040	COG2226	methyltransferase
GB849_RS13045	COG2315	Protein conserved in bacteria
GB849_RS13055	COG0658	competence protein
GB849_RS13055	COG2333	competence protein COMEC
GB849_RS13095	COG3973	AAA domain
GB849_RS13115	COG0514	ATP-dependent DNA helicase (RecQ)
GB849_RS13145	COG4637	Psort location Cytoplasmic, score
GB849_RS13165	COG3397	chitin binding
GB849_RS13180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GB849_RS13185	COG1115	amino acid carrier protein
GB849_RS13190	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS13195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GB849_RS13205	COG3938	Belongs to the proline racemase family
GB849_RS13210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GB849_RS13250	COG0586	Pfam SNARE associated Golgi protein
GB849_RS13255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GB849_RS13260	COG0519	Catalyzes the synthesis of GMP from XMP
GB849_RS13265	COG4166	transmembrane transport
GB849_RS13275	COG4948	Mandelate Racemase Muconate Lactonizing
GB849_RS13320	COG2936	dipeptidyl-peptidase activity
GB849_RS13325	COG5002	protein histidine kinase activity
GB849_RS13330	COG0745	RESPONSE REGULATOR receiver
GB849_RS13365	COG1164	Oligoendopeptidase f
GB849_RS13375	COG1307	EDD domain protein, DegV family
GB849_RS13415	COG2814	Major facilitator Superfamily
GB849_RS13425	COG1664	Polymer-forming cytoskeletal
GB849_RS13430	COG0789	Transcriptional regulator
GB849_RS13435	COG4533	DNA binding
GB849_RS13440	COG2814	Major facilitator Superfamily
GB849_RS13440	COG0477	Major facilitator Superfamily
GB849_RS13465	COG2261	transglycosylase associated protein
GB849_RS13480	COG2226	methyltransferase
GB849_RS13510	COG0436	Aminotransferase
GB849_RS13515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GB849_RS13520	COG5146	pantothenate kinase activity
GB849_RS13580	COG0628	permease
GB849_RS13590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GB849_RS13595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GB849_RS13600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GB849_RS13645	COG2746	aminoglycoside 3-N-acetyltransferase activity
GB849_RS13665	COG0697	spore germination
GB849_RS13670	COG2318	DinB family
GB849_RS13690	COG4912	Dna alkylation repair
GB849_RS13700	COG0346	lactoylglutathione lyase activity
GB849_RS13715	COG0861	Integral membrane protein TerC family
GB849_RS13720	COG1368	sulfuric ester hydrolase activity
GB849_RS13725	COG0488	(ABC) transporter
GB849_RS13735	COG1033	growth of symbiont in host cell
GB849_RS13735	COG2409	Drug exporters of the RND superfamily
GB849_RS13740	COG1309	transcriptional regulator
GB849_RS13755	COG0287	Prephenate dehydrogenase
GB849_RS13760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GB849_RS13770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GB849_RS13770	COG1605	Chorismate mutase
GB849_RS13820	COG1172	Belongs to the binding-protein-dependent transport system permease family
GB849_RS13830	COG2390	Transcriptional regulator
GB849_RS13835	COG1070	Carbohydrate kinase
GB849_RS13855	COG2329	Antibiotic biosynthesis monooxygenase
GB849_RS13870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS13885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GB849_RS13890	COG4187	Peptidase family M20/M25/M40
GB849_RS13895	COG1414	Transcriptional regulator
GB849_RS13900	COG0833	amino acid
GB849_RS13905	COG1690	Belongs to the RtcB family
GB849_RS13910	COG3239	Fatty acid desaturase
GB849_RS13930	COG3655	Transcriptional regulator
GB849_RS13945	COG4377	Putative membrane peptidase family (DUF2324)
GB849_RS13955	COG3279	Response regulator of the LytR AlgR family
GB849_RS13970	COG0346	lactoylglutathione lyase activity
GB849_RS13990	COG0714	Associated with various cellular activities
GB849_RS14010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GB849_RS14015	COG0753	catalase activity
GB849_RS14020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GB849_RS14040	COG1846	Transcriptional regulator
GB849_RS14045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GB849_RS14070	COG0714	Associated with various cellular activities
GB849_RS14080	COG0778	Nitroreductase
GB849_RS14085	COG1846	Transcriptional regulator
GB849_RS14120	COG1725	Transcriptional regulator
GB849_RS14130	COG1136	(ABC) transporter
GB849_RS14160	COG0456	acetyltransferase
GB849_RS14175	COG0697	spore germination
GB849_RS14180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS14220	COG0730	response to heat
GB849_RS14230	COG0833	amino acid
GB849_RS14240	COG4335	DNA alkylation repair
GB849_RS14280	COG0768	penicillin binding
GB849_RS14315	COG1984	allophanate hydrolase subunit 2
GB849_RS14320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GB849_RS14325	COG1414	Transcriptional regulator
GB849_RS14335	COG3142	Participates in the control of copper homeostasis
GB849_RS14340	COG0860	N-Acetylmuramoyl-L-alanine amidase
GB849_RS14345	COG0640	Transcriptional regulator
GB849_RS14355	COG2814	Major facilitator Superfamily
GB849_RS14360	COG1960	acyl-CoA dehydrogenase activity
GB849_RS14375	COG3314	Sporulation integral membrane protein YlbJ
GB849_RS14400	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GB849_RS14415	COG0574	Belongs to the PEP-utilizing enzyme family
GB849_RS14415	COG3848	Pyruvate phosphate dikinase
GB849_RS14425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS14440	COG5577	PFAM Coat F domain
GB849_RS14445	COG3403	YqcI/YcgG family
GB849_RS14450	COG1280	lysine exporter protein (LysE YggA)
GB849_RS14455	COG1113	amino acid transport
GB849_RS14480	COG1063	alcohol dehydrogenase
GB849_RS14490	COG1027	Aspartate ammonia-lyase
GB849_RS14495	COG0252	asparaginase activity
GB849_RS14500	COG1396	sequence-specific DNA binding
GB849_RS14505	COG2801	Transposase and inactivated derivatives
GB849_RS14510	COG0322	excinuclease ABC activity
GB849_RS14515	COG0531	amino acid
GB849_RS14520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GB849_RS14530	COG0531	amino acid
GB849_RS14535	COG0697	spore germination
GB849_RS14540	COG0784	Response regulator, receiver
GB849_RS14545	COG4191	Histidine kinase
GB849_RS14550	COG2066	Belongs to the glutaminase family
GB849_RS14555	COG1115	amino acid carrier protein
GB849_RS14575	COG0723	plastoquinol--plastocyanin reductase activity
GB849_RS14575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GB849_RS14580	COG0534	Mate efflux family protein
GB849_RS14590	COG0531	amino acid
GB849_RS14595	COG0737	Belongs to the 5'-nucleotidase family
GB849_RS14600	COG0753	catalase activity
GB849_RS14605	COG0598	Magnesium transport protein CorA
GB849_RS14655	COG0415	Belongs to the DNA photolyase family
GB849_RS14670	COG0288	reversible hydration of carbon dioxide
GB849_RS14680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GB849_RS14685	COG5609	conserved protein (DUF2294)
GB849_RS14700	COG0697	spore germination
GB849_RS14710	COG1575	Belongs to the MenA family. Type 1 subfamily
GB849_RS14715	COG4641	Protein conserved in bacteria
GB849_RS14740	COG3347	Dehydrogenase
GB849_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS14750	COG1070	Carbohydrate kinase
GB849_RS14755	COG0235	Class ii aldolase
GB849_RS14765	COG1172	Belongs to the binding-protein-dependent transport system permease family
GB849_RS14775	COG4154	Belongs to the RbsD FucU family
GB849_RS14790	COG0798	PFAM Bile acid sodium symporter
GB849_RS14795	COG0346	lactoylglutathione lyase activity
GB849_RS14800	COG0640	Transcriptional regulator
GB849_RS14810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GB849_RS14830	COG1136	(ABC) transporter
GB849_RS14880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GB849_RS14880	COG3320	Male sterility
GB849_RS14885	COG1309	transcriptional regulator
GB849_RS14890	COG2814	Major facilitator Superfamily
GB849_RS14895	COG1309	transcriptional regulator
GB849_RS14900	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS14905	COG1522	sequence-specific DNA binding
GB849_RS14920	COG0346	lactoylglutathione lyase activity
GB849_RS14960	COG2814	Major facilitator Superfamily
GB849_RS14970	COG4895	conserved protein (DUF2196)
GB849_RS15015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GB849_RS15045	COG0789	Transcriptional regulator
GB849_RS15050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GB849_RS15070	COG0577	efflux transmembrane transporter activity
GB849_RS15090	COG5002	protein histidine kinase activity
GB849_RS15090	COG3850	Histidine kinase
GB849_RS15100	COG2364	Membrane
GB849_RS15105	COG1846	Transcriptional regulator
GB849_RS15110	COG0456	acetyltransferase
GB849_RS15115	COG2808	Putative FMN-binding domain
GB849_RS15120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS15150	COG1619	proteins homologs of microcin C7 resistance protein MccF
GB849_RS15165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GB849_RS15185	COG0662	Cupin 2, conserved barrel domain protein
GB849_RS15190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS15190	COG2207	Transcriptional regulator
GB849_RS15210	COG3409	Peptidoglycan-binding domain 1 protein
GB849_RS15210	COG5632	N-Acetylmuramoyl-L-alanine amidase
GB849_RS15250	COG0477	Major facilitator Superfamily
GB849_RS15265	COG1846	Transcriptional regulator
GB849_RS15270	COG2814	Major facilitator Superfamily
GB849_RS15280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GB849_RS15285	COG1131	(ABC) transporter
GB849_RS15305	COG2076	Multidrug Resistance protein
GB849_RS15310	COG1309	transcriptional regulator
GB849_RS15325	COG2031	fatty acid transporter
GB849_RS15335	COG2249	NAD(P)H dehydrogenase (quinone) activity
GB849_RS15370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GB849_RS15385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GB849_RS15390	COG1288	antiporter activity
GB849_RS15410	COG0789	Transcriptional regulator
GB849_RS15430	COG3344	reverse transcriptase
GB849_RS15435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GB849_RS15435	COG0456	acetyltransferase
GB849_RS15440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GB849_RS15460	COG1733	regulation of RNA biosynthetic process
GB849_RS15465	COG0778	Nitroreductase
GB849_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS15495	COG1131	(ABC) transporter
GB849_RS15520	COG1011	Hydrolase
GB849_RS15525	COG2365	Tyrosine phosphatase family
GB849_RS15545	COG0346	lactoylglutathione lyase activity
GB849_RS15550	COG1940	carbohydrate kinase activity
GB849_RS15555	COG0110	maltose O-acetyltransferase activity
GB849_RS15570	COG0628	permease
GB849_RS15595	COG2226	methyltransferase
GB849_RS15605	COG0477	Major facilitator Superfamily
GB849_RS15630	COG1253	flavin adenine dinucleotide binding
GB849_RS15635	COG0789	Transcriptional regulator
GB849_RS15645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GB849_RS15675	COG0697	spore germination
GB849_RS15680	COG1357	PFAM Pentapeptide repeats (8 copies)
GB849_RS15685	COG3813	Protein conserved in bacteria
GB849_RS15690	COG2706	6-phosphogluconolactonase activity
GB849_RS15695	COG1070	Carbohydrate kinase
GB849_RS15705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GB849_RS15710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GB849_RS15720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GB849_RS15725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GB849_RS15730	COG0604	alcohol dehydrogenase
GB849_RS15735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GB849_RS15745	COG3321	synthase
GB849_RS15745	COG0604	alcohol dehydrogenase
GB849_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS15765	COG0656	L-ascorbic acid biosynthetic process
GB849_RS15770	COG2814	Major facilitator Superfamily
GB849_RS15785	COG0814	amino acid
GB849_RS15810	COG1393	Belongs to the ArsC family
GB849_RS15815	COG1733	regulation of RNA biosynthetic process
GB849_RS15820	COG2188	Transcriptional regulator
GB849_RS15825	COG0673	inositol 2-dehydrogenase activity
GB849_RS15830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GB849_RS15835	COG1733	regulation of RNA biosynthetic process
GB849_RS15840	COG1733	regulation of RNA biosynthetic process
GB849_RS15860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS15910	COG1695	Transcriptional regulator
GB849_RS15915	COG0604	alcohol dehydrogenase
GB849_RS15920	COG1113	amino acid transport
GB849_RS15925	COG2814	Major facilitator Superfamily
GB849_RS15950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GB849_RS15955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GB849_RS15970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS15975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS15980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS15985	COG3739	integral membrane protein
GB849_RS16015	COG0583	DNA-binding transcription factor activity
GB849_RS16035	COG1193	negative regulation of DNA recombination
GB849_RS16040	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GB849_RS16045	COG1164	Oligoendopeptidase f
GB849_RS16050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GB849_RS16075	COG0584	glycerophosphoryl diester phosphodiesterase
GB849_RS16085	COG0640	Transcriptional regulator
GB849_RS16090	COG0604	alcohol dehydrogenase
GB849_RS16100	COG0457	Tetratricopeptide repeat
GB849_RS16125	COG2808	Putative FMN-binding domain
GB849_RS16130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GB849_RS16140	COG0385	Bile acid
GB849_RS16145	COG0277	FAD linked oxidase domain protein
GB849_RS16175	COG1285	pathogenesis
GB849_RS16190	COG2514	catechol 2,3-dioxygenase activity
GB849_RS16195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS16200	COG1126	abc transporter atp-binding protein
GB849_RS16205	COG0765	amino acid transport
GB849_RS16210	COG2720	vancomycin resistance protein
GB849_RS16245	COG0716	FMN binding
GB849_RS16255	COG0494	nUDIX hydrolase
GB849_RS16275	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS16285	COG0165	Argininosuccinate lyase
GB849_RS16300	COG4145	pantothenate transmembrane transporter activity
GB849_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS16355	COG1657	PFAM Prenyltransferase squalene oxidase
GB849_RS16360	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GB849_RS16365	COG2962	Rard protein
GB849_RS16370	COG3326	Membrane
GB849_RS16385	COG0489	protein tyrosine kinase activity
GB849_RS16395	COG0314	molybdopterin synthase activity
GB849_RS16400	COG0303	'Molybdopterin
GB849_RS16405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GB849_RS16410	COG2116	formate transmembrane transporter activity
GB849_RS16420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GB849_RS16425	COG5609	conserved protein (DUF2294)
GB849_RS16430	COG2427	Protein of unknown function (DUF1641)
GB849_RS16435	COG3383	formate dehydrogenase (NAD+) activity
GB849_RS16440	COG0697	spore germination
GB849_RS16480	COG2226	methyltransferase
GB849_RS16485	COG4166	transmembrane transport
GB849_RS16490	COG4166	transmembrane transport
GB849_RS16495	COG4166	transmembrane transport
GB849_RS16500	COG1301	dicarboxylic acid transport
GB849_RS16505	COG1316	TRANSCRIPTIONal
GB849_RS16515	COG1595	DNA-templated transcription, initiation
GB849_RS16520	COG0346	lactoylglutathione lyase activity
GB849_RS16530	COG1131	(ABC) transporter
GB849_RS16540	COG0673	inositol 2-dehydrogenase activity
GB849_RS16545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GB849_RS16550	COG0187	DNA topoisomerase II activity
GB849_RS16555	COG1832	CoA-binding protein
GB849_RS16560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GB849_RS16565	COG0745	RESPONSE REGULATOR receiver
GB849_RS16575	COG1328	CTP reductase activity
GB849_RS16575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GB849_RS16585	COG4841	protein insertion into membrane
GB849_RS16590	COG0824	Thioesterase
GB849_RS16620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS16630	COG1132	(ABC) transporter
GB849_RS16635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GB849_RS16665	COG2211	Major facilitator Superfamily
GB849_RS16665	COG2211	Major facilitator Superfamily
GB849_RS16670	COG4282	regulation of fungal-type cell wall biogenesis
GB849_RS16690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GB849_RS16715	COG0183	Belongs to the thiolase family
GB849_RS16720	COG0318	PFAM AMP-dependent synthetase and ligase
GB849_RS16725	COG1268	BioY protein
GB849_RS16730	COG0318	PFAM AMP-dependent synthetase and ligase
GB849_RS16745	COG1396	sequence-specific DNA binding
GB849_RS16790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS16800	COG5002	protein histidine kinase activity
GB849_RS16805	COG0400	carboxylic ester hydrolase activity
GB849_RS16810	COG0346	lactoylglutathione lyase activity
GB849_RS16815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GB849_RS16825	COG0069	glutamate synthase activity
GB849_RS16830	COG1902	pentaerythritol trinitrate reductase activity
GB849_RS16835	COG1329	Transcriptional regulator
GB849_RS16840	COG0010	Belongs to the arginase family
GB849_RS16865	COG2226	methyltransferase
GB849_RS16905	COG4846	Membrane protein involved in cytochrome C biogenesis
GB849_RS16910	COG0785	Cytochrome C biogenesis protein
GB849_RS16920	COG1473	amidohydrolase
GB849_RS16930	COG1131	(ABC) transporter
GB849_RS16940	COG0583	DNA-binding transcription factor activity
GB849_RS16950	COG1346	cytolysis
GB849_RS16965	COG0730	response to heat
GB849_RS16975	COG3409	Peptidoglycan-binding domain 1 protein
GB849_RS16975	COG5632	N-Acetylmuramoyl-L-alanine amidase
GB849_RS16990	COG1132	(ABC) transporter
GB849_RS16995	COG1132	(ABC) transporter
GB849_RS17105	COG3639	organic phosphonate transmembrane transporter activity
GB849_RS17110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GB849_RS17115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS17120	COG0737	Belongs to the 5'-nucleotidase family
GB849_RS17130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GB849_RS17150	COG1695	Transcriptional regulator
GB849_RS17155	COG0174	glutamine synthetase
GB849_RS17160	COG0789	Transcriptional regulator
GB849_RS17165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GB849_RS17170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GB849_RS17175	COG2860	membrane
GB849_RS17180	COG0464	growth
GB849_RS17210	COG1388	LysM domain
GB849_RS17210	COG3584	3D domain protein
GB849_RS17215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GB849_RS17215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GB849_RS17215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GB849_RS17220	COG1105	Belongs to the carbohydrate kinase PfkB family
GB849_RS17225	COG1349	DNA-binding transcription factor activity
GB849_RS17230	COG1979	alcohol dehydrogenase
GB849_RS17235	COG2322	membrane
GB849_RS17245	COG1113	amino acid transport
GB849_RS17255	COG1408	metallophosphoesterase
GB849_RS17260	COG2116	formate transmembrane transporter activity
GB849_RS17275	COG2217	Heavy metal translocating P-type atpase
GB849_RS17280	COG2608	mercury ion transmembrane transporter activity
GB849_RS17285	COG1937	Protein conserved in bacteria
GB849_RS17295	COG2819	hydrolase of the alpha beta superfamily
GB849_RS17300	COG1120	ATPase activity
GB849_RS17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS17310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS17315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS17325	COG2169	Transcriptional regulator
GB849_RS17330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GB849_RS17335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GB849_RS17345	COG2364	Membrane
GB849_RS17355	COG5001	Diguanylate cyclase
GB849_RS17355	COG3300	MHYT domain
GB849_RS17370	COG1380	Effector of murein hydrolase LrgA
GB849_RS17375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GB849_RS17400	COG3773	Cell wall hydrolase
GB849_RS17415	COG1368	sulfuric ester hydrolase activity
GB849_RS17420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GB849_RS17430	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GB849_RS17455	COG1131	(ABC) transporter
GB849_RS17480	COG4550	Control of competence regulator ComK, YlbF/YmcA
GB849_RS17490	COG1013	pyruvate-flavodoxin oxidoreductase activity
GB849_RS17495	COG0674	pyruvate-flavodoxin oxidoreductase activity
GB849_RS17495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GB849_RS17505	COG2359	stage V sporulation protein S
GB849_RS17510	COG1692	metallophosphoesterase
GB849_RS17515	COG1418	mRNA catabolic process
GB849_RS17535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GB849_RS17540	COG1426	Protein conserved in bacteria
GB849_RS17555	COG0300	oxidoreductase activity
GB849_RS17560	COG0612	Peptidase, M16
GB849_RS17565	COG0612	Peptidase, M16
GB849_RS17570	COG1079	Belongs to the binding-protein-dependent transport system permease family
GB849_RS17575	COG4603	Belongs to the binding-protein-dependent transport system permease family
GB849_RS17580	COG3845	ABC transporter
GB849_RS17585	COG1744	ABC transporter substrate-binding protein PnrA-like
GB849_RS17590	COG2188	Transcriptional regulator
GB849_RS17595	COG1674	ftsk spoiiie
GB849_RS17605	COG0740	serine-type endopeptidase activity
GB849_RS17610	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GB849_RS17620	COG0527	aspartate kinase activity
GB849_RS17625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GB849_RS17630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GB849_RS17635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GB849_RS17640	COG1873	PFAM PRC-barrel domain
GB849_RS17645	COG0612	Peptidase, M16
GB849_RS17650	COG0726	polysaccharide deacetylase
GB849_RS17665	COG0196	riboflavin kinase activity
GB849_RS17680	COG1550	Protein conserved in bacteria
GB849_RS17690	COG1358	cellular component organization or biogenesis
GB849_RS17695	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GB849_RS17700	COG0195	Participates in both transcription termination and antitermination
GB849_RS17720	COG0750	zinc metalloprotease
GB849_RS17730	COG4589	Belongs to the CDS family
GB849_RS17745	COG0528	UMP kinase activity
GB849_RS17775	COG4974	Belongs to the 'phage' integrase family
GB849_RS17785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GB849_RS17790	COG0758	DNA mediated transformation
GB849_RS17795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GB849_RS17835	COG1837	Belongs to the UPF0109 family
GB849_RS17845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GB849_RS17855	COG0552	protein localization to endoplasmic reticulum
GB849_RS17860	COG1196	nuclear chromosome segregation
GB849_RS17870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GB849_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS17880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GB849_RS17895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GB849_RS17900	COG1461	Dihydroxyacetone kinase
GB849_RS17905	COG1302	Protein conserved in bacteria
GB849_RS17920	COG1564	THIamine pyrophosphokinase
GB849_RS17925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GB849_RS17935	COG0515	serine threonine protein kinase
GB849_RS17935	COG2815	serine threonine protein kinase
GB849_RS17940	COG0631	protein serine/threonine phosphatase activity
GB849_RS17950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GB849_RS17950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GB849_RS17960	COG0242	peptide deformylase activity
GB849_RS17965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GB849_RS17970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GB849_RS17990	COG1561	YicC-like family, N-terminal region
GB849_RS17995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GB849_RS18005	COG0006	proline dipeptidase activity
GB849_RS18025	COG3069	C4-dicarboxylate transmembrane transporter activity
GB849_RS18090	COG0564	pseudouridine synthase activity
GB849_RS18110	COG3599	regulation of cell shape
GB849_RS18115	COG2302	S4 RNA-binding domain
GB849_RS18120	COG0762	integral membrane protein
GB849_RS18130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GB849_RS18140	COG1873	PFAM PRC-barrel domain
GB849_RS18145	COG1191	sigma factor activity
GB849_RS18150	COG1191	sigma factor activity
GB849_RS18165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GB849_RS18170	COG0849	cell division
GB849_RS18175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GB849_RS18190	COG0772	Belongs to the SEDS family
GB849_RS18205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GB849_RS18210	COG0768	penicillin binding
GB849_RS18215	COG0768	penicillin binding
GB849_RS18220	COG4839	cell division protein FtsL
GB849_RS18235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GB849_RS18250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GB849_RS18255	COG1399	metal-binding, possibly nucleic acid-binding protein
GB849_RS18370	COG0740	serine-type endopeptidase activity
GB849_RS18380	COG1802	Transcriptional regulator
GB849_RS18380	COG4626	Terminase
GB849_RS18420	COG0582	viral genome integration into host DNA
GB849_RS18475	COG1484	DNA-dependent DNA replication
GB849_RS18500	COG1396	sequence-specific DNA binding
GB849_RS18540	COG0582	viral genome integration into host DNA
GB849_RS18550	COG3480	Lon protease (S16) C-terminal proteolytic domain
GB849_RS18555	COG1752	Esterase of the alpha-beta hydrolase superfamily
GB849_RS18560	COG3314	Sporulation integral membrane protein YlbJ
GB849_RS18570	COG0742	ribosomal rna small subunit methyltransferase
GB849_RS18595	COG3679	Belongs to the UPF0342 family
GB849_RS18600	COG0406	alpha-ribazole phosphatase activity
GB849_RS18615	COG2340	Cysteine-rich secretory protein family
GB849_RS18640	COG3336	cytochrome c oxidase
GB849_RS18675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GB849_RS18680	COG0772	Belongs to the SEDS family
GB849_RS18690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GB849_RS18695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GB849_RS18705	COG4896	Protein conserved in bacteria
GB849_RS18720	COG1217	gtp-binding protein TYPA
GB849_RS18730	COG0483	inositol monophosphate 1-phosphatase activity
GB849_RS18750	COG1982	Orn Lys Arg decarboxylase major
GB849_RS18800	COG0022	dehydrogenase e1 component
GB849_RS18805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GB849_RS18815	COG0242	peptide deformylase activity
GB849_RS18820	COG0561	phosphatase activity
GB849_RS18830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GB849_RS18835	COG0569	domain protein
GB849_RS18855	COG0583	DNA-binding transcription factor activity
GB849_RS18860	COG0517	IMP dehydrogenase activity
GB849_RS18870	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GB849_RS18875	COG4703	Protein of unknown function (DUF1797)
GB849_RS18890	COG2200	EAL domain
GB849_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS18900	COG1408	metallophosphoesterase
GB849_RS18910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GB849_RS18945	COG2814	Major facilitator Superfamily
GB849_RS18970	COG3209	COG3209 Rhs family protein
GB849_RS18980	COG2205	protein histidine kinase activity
GB849_RS18990	COG0436	Aminotransferase
GB849_RS18995	COG1609	Transcriptional regulator
GB849_RS19000	COG3833	ABC-type maltose transport systems, permease component
GB849_RS19005	COG1175	transmembrane transport
GB849_RS19010	COG2182	Extracellular solute-binding protein
GB849_RS19020	COG0366	Alpha amylase catalytic
GB849_RS19025	COG3842	ATPase activity
GB849_RS19065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GB849_RS19070	COG0183	Belongs to the thiolase family
GB849_RS19110	COG1695	Transcriptional regulator
GB849_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS19145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GB849_RS19150	COG0436	Aminotransferase
GB849_RS19185	COG2084	Dehydrogenase
GB849_RS19195	COG2199	diguanylate cyclase activity
GB849_RS19200	COG0778	Nitroreductase
GB849_RS19225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GB849_RS19225	COG2190	(PTS) system
GB849_RS19225	COG1263	PTS System
GB849_RS19230	COG3711	transcriptional antiterminator
GB849_RS19240	COG2188	Transcriptional regulator
GB849_RS19250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GB849_RS19275	COG1547	Domain of unknown function (DUF309)
GB849_RS19280	COG0456	acetyltransferase
GB849_RS19285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GB849_RS19290	COG4086	secreted protein
GB849_RS19295	COG0561	phosphatase activity
GB849_RS19300	COG0697	spore germination
GB849_RS19315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GB849_RS19340	COG0733	neurotransmitter:sodium symporter activity
GB849_RS19360	COG1686	Belongs to the peptidase S11 family
GB849_RS19365	COG1725	Transcriptional regulator
GB849_RS19370	COG1131	(ABC) transporter
GB849_RS19385	COG1846	Transcriptional regulator
GB849_RS19400	COG0598	Magnesium transport protein CorA
GB849_RS19425	COG4974	Belongs to the 'phage' integrase family
GB849_RS19435	COG0735	belongs to the Fur family
GB849_RS19440	COG1300	Membrane
GB849_RS19460	COG0667	Aldo Keto reductase
GB849_RS19465	COG0656	L-ascorbic acid biosynthetic process
GB849_RS19470	COG0456	acetyltransferase
GB849_RS19470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GB849_RS19480	COG1525	nuclease
GB849_RS19480	COG4085	toxin activity
GB849_RS19480	COG0737	Belongs to the 5'-nucleotidase family
GB849_RS19490	COG0596	Alpha beta hydrolase
GB849_RS19495	COG2056	Na+-H+ antiporter family
GB849_RS19500	COG1609	Transcriptional regulator
GB849_RS19505	COG0456	acetyltransferase
GB849_RS19510	COG1073	alpha beta
GB849_RS19525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GB849_RS19525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GB849_RS19530	COG0307	riboflavin synthase, alpha
GB849_RS19555	COG4106	trans-aconitate 2-methyltransferase activity
GB849_RS19560	COG1073	alpha beta
GB849_RS19560	COG2226	methyltransferase
GB849_RS19575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GB849_RS19585	COG1757	Na H antiporter
GB849_RS19590	COG0737	Belongs to the 5'-nucleotidase family
GB849_RS19600	COG1522	sequence-specific DNA binding
GB849_RS19620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GB849_RS19645	COG0300	oxidoreductase activity
GB849_RS19650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS19655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GB849_RS19660	COG1760	l-serine dehydratase
GB849_RS19665	COG1760	l-serine dehydratase
GB849_RS19695	COG2195	Cleaves the N-terminal amino acid of tripeptides
GB849_RS19700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS19715	COG1376	ErfK ybiS ycfS ynhG family protein
GB849_RS19720	COG4129	membrane
GB849_RS19725	COG1126	abc transporter atp-binding protein
GB849_RS19730	COG0765	amino acid transport
GB849_RS19735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GB849_RS19750	COG2323	membrane
GB849_RS19755	COG0772	Belongs to the SEDS family
GB849_RS19760	COG0508	dehydrogenase complex catalyzes the overall conversion of
GB849_RS19765	COG0022	dehydrogenase e1 component
GB849_RS19770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GB849_RS19775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GB849_RS19790	COG0280	phosphate acetyltransferase
GB849_RS19795	COG3829	transcription factor binding
GB849_RS19795	COG3290	protein histidine kinase activity
GB849_RS19805	COG0584	glycerophosphoryl diester phosphodiesterase
GB849_RS19810	COG3093	addiction module antidote protein HigA
GB849_RS19815	COG0745	RESPONSE REGULATOR receiver
GB849_RS19820	COG0750	zinc metalloprotease
GB849_RS19825	COG0497	DNA recombination
GB849_RS19840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GB849_RS19850	COG0142	geranyltranstransferase activity
GB849_RS19875	COG1302	Protein conserved in bacteria
GB849_RS19880	COG0439	Biotin carboxylase
GB849_RS19885	COG0511	ligase activity, forming carbon-carbon bonds
GB849_RS19930	COG3854	ATPases associated with a variety of cellular activities
GB849_RS19955	COG0006	proline dipeptidase activity
GB849_RS19970	COG3872	metal-dependent enzyme
GB849_RS20010	COG0095	Lipoate-protein ligase
GB849_RS20015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GB849_RS20020	COG1609	Transcriptional regulator
GB849_RS20030	COG2076	Multidrug Resistance protein
GB849_RS20035	COG2076	Multidrug Resistance protein
GB849_RS20070	COG1131	(ABC) transporter
GB849_RS20075	COG1725	Transcriptional regulator
GB849_RS20105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GB849_RS20160	COG4970	Tfp pilus assembly protein FimT
GB849_RS20170	COG1459	type II secretion system
GB849_RS20175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GB849_RS20230	COG0646	methionine synthase
GB849_RS20230	COG1410	methionine synthase
GB849_RS20235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GB849_RS20235	COG0646	methionine synthase
GB849_RS20240	COG0626	cystathionine gamma-synthase activity
GB849_RS20245	COG0626	cystathionine gamma-synthase activity
GB849_RS20265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS20275	COG1940	carbohydrate kinase activity
GB849_RS20280	COG4483	Protein conserved in bacteria
GB849_RS20285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GB849_RS20290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GB849_RS20295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GB849_RS20300	COG0704	Plays a role in the regulation of phosphate uptake
GB849_RS20310	COG0581	inorganic phosphate transmembrane transporter activity
GB849_RS20315	COG0573	inorganic phosphate transmembrane transporter activity
GB849_RS20320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GB849_RS20325	COG0768	penicillin binding
GB849_RS20330	COG0477	Major facilitator Superfamily
GB849_RS20335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GB849_RS20360	COG0735	belongs to the Fur family
GB849_RS20365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GB849_RS20370	COG1121	(ABC) transporter
GB849_RS20375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS20405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GB849_RS20410	COG2384	SAM-dependent methyltransferase
GB849_RS20415	COG2010	Cytochrome c
GB849_RS20420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GB849_RS20425	COG0358	DNA primase activity
GB849_RS20435	COG0517	IMP dehydrogenase activity
GB849_RS20450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GB849_RS20455	COG0295	cytidine deaminase activity
GB849_RS20460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GB849_RS20470	COG1480	7TM receptor with intracellular HD hydrolase
GB849_RS20475	COG1702	phosphate starvation-inducible protein PhoH
GB849_RS20490	COG1610	YqeY-like protein
GB849_RS20495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GB849_RS20500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GB849_RS20505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GB849_RS20535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GB849_RS20540	COG1733	regulation of RNA biosynthetic process
GB849_RS20565	COG1466	dna polymerase III delta subunit
GB849_RS20575	COG0658	competence protein
GB849_RS20575	COG2333	competence protein COMEC
GB849_RS20580	COG2131	deaminase
GB849_RS20585	COG1596	polysaccharide export
GB849_RS20585	COG1555	photosystem II stabilization
GB849_RS20590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GB849_RS20595	COG2226	methyltransferase
GB849_RS20600	COG0799	negative regulation of ribosome biogenesis
GB849_RS20605	COG1713	HD superfamily hydrolase involved in NAD metabolism
GB849_RS20615	COG1534	Rna-binding protein
GB849_RS20625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GB849_RS20630	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GB849_RS20665	COG2357	RelA SpoT domain protein
GB849_RS20675	COG1785	Belongs to the alkaline phosphatase family
GB849_RS20680	COG0456	acetyltransferase
GB849_RS20685	COG2267	carboxylic ester hydrolase activity
GB849_RS20720	COG1404	Belongs to the peptidase S8 family
GB849_RS20725	COG3186	Phenylalanine-4-hydroxylase
GB849_RS20735	COG2514	catechol 2,3-dioxygenase activity
GB849_RS20740	COG2259	Doxx family
GB849_RS20780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GB849_RS20790	COG1454	alcohol dehydrogenase
GB849_RS20790	COG1012	belongs to the aldehyde dehydrogenase family
GB849_RS20795	COG0626	cystathionine gamma-synthase activity
GB849_RS20800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GB849_RS20825	COG0768	penicillin binding
GB849_RS20840	COG0826	peptidase U32
GB849_RS20845	COG0826	peptidase U32
GB849_RS20850	COG4122	O-methyltransferase activity
GB849_RS20855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GB849_RS20885	COG0628	permease
GB849_RS20905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GB849_RS20925	COG1959	2 iron, 2 sulfur cluster binding
GB849_RS20930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GB849_RS20940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GB849_RS20965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GB849_RS20975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GB849_RS20975	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GB849_RS20980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GB849_RS20985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GB849_RS20985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GB849_RS20995	COG2244	polysaccharide biosynthetic process
GB849_RS21000	COG2323	membrane
GB849_RS21010	COG1862	Preprotein translocase
GB849_RS21065	COG0157	Belongs to the NadC ModD family
GB849_RS21070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GB849_RS21075	COG1104	cysteine desulfurase activity
GB849_RS21080	COG1827	regulation of RNA biosynthetic process
GB849_RS21085	COG2258	MOSC domain
GB849_RS21090	COG0077	Prephenate dehydratase
GB849_RS21095	COG0577	efflux transmembrane transporter activity
GB849_RS21100	COG0577	efflux transmembrane transporter activity
GB849_RS21105	COG1136	(ABC) transporter
GB849_RS21110	COG5002	protein histidine kinase activity
GB849_RS21115	COG0745	RESPONSE REGULATOR receiver
GB849_RS21125	COG3290	protein histidine kinase activity
GB849_RS21135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GB849_RS21140	COG1530	ribonuclease E activity
GB849_RS21145	COG1994	Peptidase M50
GB849_RS21150	COG0739	heme binding
GB849_RS21155	COG2894	cell division
GB849_RS21175	COG1077	Cell shape determining protein MreB Mrl
GB849_RS21195	COG0285	dihydrofolate synthase activity
GB849_RS21220	COG1388	LysM domain
GB849_RS21230	COG0113	porphobilinogen synthase activity
GB849_RS21235	COG1587	Uroporphyrinogen-III synthase
GB849_RS21245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GB849_RS21255	COG1846	Transcriptional regulator
GB849_RS21260	COG1764	response to oxidative stress
GB849_RS21275	COG1067	ATP-dependent peptidase activity
GB849_RS21275	COG0470	DNA polymerase III
GB849_RS21325	COG0622	Phosphoesterase
GB849_RS21340	COG5401	PFAM Sporulation and spore germination
GB849_RS21360	COG1309	transcriptional regulator
GB849_RS21375	COG2197	response regulator
GB849_RS21380	COG2233	PERMEase
GB849_RS21385	COG0402	S-adenosylhomocysteine deaminase activity
GB849_RS21390	COG1983	PspC domain protein
GB849_RS21395	COG1396	sequence-specific DNA binding
GB849_RS21400	COG0697	spore germination
GB849_RS21410	COG1959	2 iron, 2 sulfur cluster binding
GB849_RS21415	COG1668	transmembrane transport
GB849_RS21420	COG4152	abc transporter atp-binding protein
GB849_RS21425	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GB849_RS21430	COG1360	Flagellar Motor Protein
GB849_RS21435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GB849_RS21440	COG1876	peptidase activity
GB849_RS21445	COG0824	Thioesterase
GB849_RS21450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GB849_RS21455	COG1053	succinate dehydrogenase
GB849_RS21460	COG2009	succinate dehydrogenase
GB849_RS21465	COG1719	4-vinyl reductase, 4VR
GB849_RS21475	COG3118	belongs to the thioredoxin family
GB849_RS21480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GB849_RS21485	COG2086	electron transfer activity
GB849_RS21490	COG1024	Enoyl-CoA hydratase
GB849_RS21495	COG1309	transcriptional regulator
GB849_RS21500	COG0318	PFAM AMP-dependent synthetase and ligase
GB849_RS21510	COG2318	DinB family
GB849_RS21530	COG1131	(ABC) transporter
GB849_RS21535	COG2205	protein histidine kinase activity
GB849_RS21540	COG0745	RESPONSE REGULATOR receiver
GB849_RS21545	COG4895	conserved protein (DUF2196)
GB849_RS21550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GB849_RS21565	COG4509	Sortase family
GB849_RS21570	COG1120	ATPase activity
GB849_RS21585	COG5386	Cell surface protein
GB849_RS21590	COG5386	Cell surface protein
GB849_RS21595	COG1114	Component of the transport system for branched-chain amino acids
GB849_RS21600	COG1187	pseudouridine synthase activity
GB849_RS21610	COG1796	DNA polymerase
GB849_RS21610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GB849_RS21615	COG1286	toxin biosynthetic process
GB849_RS21660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GB849_RS21670	COG1418	mRNA catabolic process
GB849_RS21680	COG2814	Major facilitator Superfamily
GB849_RS21685	COG1566	PFAM secretion protein HlyD family protein
GB849_RS21690	COG1309	transcriptional regulator
GB849_RS21695	COG1363	Peptidase, m42
GB849_RS21720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GB849_RS21730	COG1484	DNA-dependent DNA replication
GB849_RS21735	COG3611	Membrane attachment protein
GB849_RS21745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GB849_RS21755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GB849_RS21760	COG0237	dephospho-CoA kinase activity
GB849_RS21765	COG1971	Probably functions as a manganese efflux pump
GB849_RS21775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GB849_RS21775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GB849_RS21780	COG5002	protein histidine kinase activity
GB849_RS21785	COG0745	RESPONSE REGULATOR receiver
GB849_RS21805	COG0538	isocitrate dehydrogenase activity
GB849_RS21810	COG0372	Belongs to the citrate synthase family
GB849_RS21820	COG0628	permease
GB849_RS21825	COG3030	protein affecting phage T7 exclusion by the F plasmid
GB849_RS21850	COG1725	Transcriptional regulator
GB849_RS21855	COG0281	malic enzyme
GB849_RS21860	COG0587	DNA-directed DNA polymerase activity
GB849_RS21875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GB849_RS21900	COG4109	DRTGG domain
GB849_RS21910	COG0006	proline dipeptidase activity
GB849_RS21945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS21950	COG0662	Cupin 2, conserved barrel domain protein
GB849_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
GB849_RS21970	COG0589	response to stress
GB849_RS22030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS22055	COG0827	DNA restriction-modification system
GB849_RS22060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GB849_RS22065	COG3874	Sporulation protein YtfJ
GB849_RS22080	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GB849_RS22090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GB849_RS22105	COG1104	cysteine desulfurase activity
GB849_RS22115	COG0583	DNA-binding transcription factor activity
GB849_RS22120	COG0697	spore germination
GB849_RS22125	COG1309	transcriptional regulator
GB849_RS22130	COG1956	GAF domain-containing protein
GB849_RS22135	COG0626	cystathionine gamma-synthase activity
GB849_RS22165	COG1595	DNA-templated transcription, initiation
GB849_RS22180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GB849_RS22185	COG0454	-acetyltransferase
GB849_RS22190	COG0517	IMP dehydrogenase activity
GB849_RS22195	COG0123	including yeast histone deacetylase and acetoin utilization protein
GB849_RS22210	COG0745	RESPONSE REGULATOR receiver
GB849_RS22250	COG1609	Transcriptional regulator
GB849_RS22255	COG4851	CamS sex pheromone cAM373 precursor
GB849_RS22260	COG3118	belongs to the thioredoxin family
GB849_RS22270	COG2309	aminopeptidase activity
GB849_RS22290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS22305	COG1674	ftsk spoiiie
GB849_RS22315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GB849_RS22325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS22330	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GB849_RS22335	COG1363	Peptidase, m42
GB849_RS22345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS22360	COG0510	thiamine kinase activity
GB849_RS22365	COG1523	belongs to the glycosyl hydrolase 13 family
GB849_RS22375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GB849_RS22380	COG1349	DNA-binding transcription factor activity
GB849_RS22385	COG1187	pseudouridine synthase activity
GB849_RS22390	COG2244	polysaccharide biosynthetic process
GB849_RS22395	COG2081	HI0933 family
GB849_RS22400	COG2814	Major facilitator Superfamily
GB849_RS22410	COG3832	glyoxalase III activity
GB849_RS22430	COG1329	Transcriptional regulator
GB849_RS22455	COG0314	molybdopterin synthase activity
GB849_RS22460	COG1763	Mo-molybdopterin cofactor biosynthetic process
GB849_RS22465	COG0303	'Molybdopterin
GB849_RS22475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GB849_RS22480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GB849_RS22500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GB849_RS22510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GB849_RS22550	COG2814	Major facilitator Superfamily
GB849_RS22555	COG0475	glutathione-regulated potassium exporter activity
GB849_RS22560	COG0490	domain, Protein
GB849_RS22565	COG0582	viral genome integration into host DNA
GB849_RS22575	COG1136	(ABC) transporter
GB849_RS22595	COG1242	4 iron, 4 sulfur cluster binding
GB849_RS22600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GB849_RS22615	COG1794	racemase activity, acting on amino acids and derivatives
GB849_RS22640	COG2267	carboxylic ester hydrolase activity
GB849_RS22645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GB849_RS22650	COG0671	phosphoesterase, PA-phosphatase related
GB849_RS22655	COG0438	transferase activity, transferring glycosyl groups
GB849_RS22665	COG0521	Mo-molybdopterin cofactor biosynthetic process
GB849_RS22675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS22720	COG5002	protein histidine kinase activity
GB849_RS22725	COG4191	Histidine kinase
GB849_RS22730	COG2267	carboxylic ester hydrolase activity
GB849_RS22735	COG1368	sulfuric ester hydrolase activity
GB849_RS22755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GB849_RS22760	COG1116	anion transmembrane transporter activity
GB849_RS22765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GB849_RS22790	COG0494	nUDIX hydrolase
GB849_RS22820	COG0288	reversible hydration of carbon dioxide
GB849_RS22830	COG1294	oxidase, subunit
GB849_RS22850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS22875	COG1842	Phage shock protein A
GB849_RS22910	COG5002	protein histidine kinase activity
GB849_RS22915	COG0745	RESPONSE REGULATOR receiver
GB849_RS22945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GB849_RS22950	COG1597	lipid kinase activity
GB849_RS22970	COG0577	efflux transmembrane transporter activity
GB849_RS22975	COG1136	(ABC) transporter
GB849_RS22990	COG0586	Pfam SNARE associated Golgi protein
GB849_RS23000	COG4977	sequence-specific DNA binding
GB849_RS23010	COG0577	efflux transmembrane transporter activity
GB849_RS23015	COG1136	(ABC) transporter
GB849_RS23020	COG2207	Transcriptional regulator
GB849_RS23020	COG3708	Transcriptional regulator
GB849_RS23025	COG5658	integral membrane protein
GB849_RS23030	COG0640	Transcriptional regulator
GB849_RS23035	COG0745	RESPONSE REGULATOR receiver
GB849_RS23040	COG2205	protein histidine kinase activity
GB849_RS23045	COG0577	efflux transmembrane transporter activity
GB849_RS23050	COG0577	efflux transmembrane transporter activity
GB849_RS23055	COG1136	(ABC) transporter
GB849_RS23060	COG0577	efflux transmembrane transporter activity
GB849_RS23075	COG2188	Transcriptional regulator
GB849_RS23095	COG3964	amidohydrolase
GB849_RS23115	COG4948	Mandelate Racemase Muconate Lactonizing
GB849_RS23125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GB849_RS23130	COG0596	Alpha beta hydrolase
GB849_RS23140	COG1169	isochorismate synthase
GB849_RS23145	COG1575	Belongs to the MenA family. Type 1 subfamily
GB849_RS23150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GB849_RS23175	COG0058	SHG alpha-glucan phosphorylase activity
GB849_RS23185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GB849_RS23205	COG1404	Belongs to the peptidase S8 family
GB849_RS23305	COG0544	peptidyl-prolyl cis-trans isomerase activity
GB849_RS23340	COG1285	pathogenesis
GB849_RS23345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GB849_RS23360	COG2155	Conserved Protein
GB849_RS23365	COG1098	S1 RNA binding domain
GB849_RS23370	COG0436	Aminotransferase
GB849_RS23375	COG1522	sequence-specific DNA binding
GB849_RS23380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GB849_RS23395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GB849_RS23410	COG5018	Exonuclease
GB849_RS23415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GB849_RS23435	COG2050	protein possibly involved in aromatic compounds catabolism
GB849_RS23445	COG1268	BioY protein
GB849_RS23455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GB849_RS23460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GB849_RS23475	COG3584	3D domain protein
GB849_RS23490	COG1252	NADH dehydrogenase
GB849_RS23500	COG3708	Transcriptional regulator
GB849_RS23515	COG1683	Conserved Protein
GB849_RS23535	COG0316	Belongs to the HesB IscA family
GB849_RS23550	COG1252	NADH dehydrogenase
GB849_RS23560	COG2274	protein secretion by the type I secretion system
GB849_RS23565	COG0390	transport system, permease component
GB849_RS23570	COG2824	Alkylphosphonate utilization operon protein PhnA
GB849_RS23610	COG4837	Protein of unknown function (DUF1462)
GB849_RS23615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GB849_RS23625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GB849_RS23630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GB849_RS23640	COG2249	NAD(P)H dehydrogenase (quinone) activity
GB849_RS23645	COG0647	UMP catabolic process
GB849_RS23655	COG2445	Protein of unknown function DUF86
GB849_RS23660	COG1494	fructose-1,6-bisphosphatase
GB849_RS23675	COG4470	Protein conserved in bacteria
GB849_RS23685	COG0789	Transcriptional regulator
GB849_RS23695	COG4377	Putative membrane peptidase family (DUF2324)
GB849_RS23720	COG0739	heme binding
GB849_RS23730	COG3377	Domain of unknown function (DUF1805)
GB849_RS23735	COG0737	Belongs to the 5'-nucleotidase family
GB849_RS23740	COG0719	Fe-S assembly protein
GB849_RS23745	COG0822	iron-sulfur transferase activity
GB849_RS23750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GB849_RS23755	COG0719	Fe-S assembly protein
GB849_RS23760	COG0396	ATPase activity
GB849_RS23765	COG1464	Belongs to the NlpA lipoprotein family
GB849_RS23770	COG1464	Belongs to the NlpA lipoprotein family
GB849_RS23775	COG2011	ABC-type metal ion transport system permease component
GB849_RS23780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GB849_RS23790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GB849_RS23795	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GB849_RS23805	COG1393	Belongs to the ArsC family
GB849_RS23860	COG1396	sequence-specific DNA binding
GB849_RS23870	COG1309	transcriptional regulator
GB849_RS23875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GB849_RS23880	COG1960	acyl-CoA dehydrogenase activity
GB849_RS23890	COG0183	Belongs to the thiolase family
GB849_RS23895	COG1250	3-hydroxyacyl-CoA dehydrogenase
GB849_RS23895	COG1024	Enoyl-CoA hydratase
GB849_RS23905	COG1686	Belongs to the peptidase S11 family
GB849_RS23920	COG0011	TIGRFAM Protein of
GB849_RS23925	COG0840	transmembrane signaling receptor activity
GB849_RS23945	COG2814	Major facilitator Superfamily
GB849_RS23950	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GB849_RS23960	COG0531	amino acid
GB849_RS23995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GB849_RS24030	COG0586	Pfam SNARE associated Golgi protein
GB849_RS24040	COG1376	ErfK ybiS ycfS ynhG family protein
GB849_RS24045	COG0745	RESPONSE REGULATOR receiver
GB849_RS24050	COG5002	protein histidine kinase activity
GB849_RS24080	COG0840	transmembrane signaling receptor activity
GB849_RS24085	COG2151	metal-sulfur cluster biosynthetic enzyme
GB849_RS24090	COG3227	Zinc metalloprotease (Elastase)
GB849_RS24095	COG1741	Belongs to the pirin family
GB849_RS24115	COG0490	domain, Protein
GB849_RS24120	COG1115	amino acid carrier protein
GB849_RS24125	COG0783	Belongs to the Dps family
GB849_RS24145	COG1611	Belongs to the LOG family
GB849_RS24165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS24170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS24175	COG1115	amino acid carrier protein
GB849_RS24180	COG1115	amino acid carrier protein
GB849_RS24185	COG2910	NAD(P)H-binding
GB849_RS24205	COG0656	L-ascorbic acid biosynthetic process
GB849_RS24210	COG2814	Major facilitator Superfamily
GB849_RS24215	COG1733	regulation of RNA biosynthetic process
GB849_RS24225	COG1252	NADH dehydrogenase
GB849_RS24230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GB849_RS24260	COG3290	protein histidine kinase activity
GB849_RS24260	COG0840	transmembrane signaling receptor activity
GB849_RS24270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GB849_RS24295	COG0488	(ABC) transporter
GB849_RS24300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GB849_RS24345	COG1136	(ABC) transporter
GB849_RS24365	COG0586	Pfam SNARE associated Golgi protein
GB849_RS24370	COG3963	phosphatidate phosphatase activity
GB849_RS24410	COG0756	dUTP diphosphatase activity
GB849_RS24415	COG2207	Transcriptional regulator
GB849_RS24415	COG3708	Transcriptional regulator
GB849_RS24430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GB849_RS24435	COG2814	Major facilitator Superfamily
GB849_RS24445	COG0640	Transcriptional regulator
GB849_RS24460	COG2311	Membrane
GB849_RS24480	COG0557	exoribonuclease II activity
GB849_RS24485	COG1647	Serine aminopeptidase, S33
GB849_RS24490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GB849_RS24495	COG1346	cytolysis
GB849_RS24530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GB849_RS24545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GB849_RS24570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GB849_RS24585	COG2323	membrane
GB849_RS24600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GB849_RS24610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GB849_RS24620	COG1051	belongs to the nudix hydrolase family
GB849_RS24630	COG0492	ferredoxin-NADP+ reductase activity
GB849_RS24635	COG0457	Tetratricopeptide repeat
GB849_RS24640	COG0110	maltose O-acetyltransferase activity
GB849_RS24660	COG1950	PFAM Membrane protein of
GB849_RS24670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GB849_RS24685	COG0789	Transcriptional regulator
GB849_RS24720	COG0583	DNA-binding transcription factor activity
GB849_RS24730	COG0655	NAD(P)H dehydrogenase (quinone) activity
GB849_RS24735	COG0488	(ABC) transporter
GB849_RS24745	COG1132	(ABC) transporter
GB849_RS24750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GB849_RS24755	COG3409	Peptidoglycan-binding domain 1 protein
GB849_RS24755	COG0793	Belongs to the peptidase S41A family
GB849_RS24760	COG2177	Part of the ABC transporter FtsEX involved in
GB849_RS24765	COG2884	Cell division ATP-binding protein ftsE
GB849_RS24785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GB849_RS24790	COG1278	Cold shock
GB849_RS24795	COG1040	competence protein
GB849_RS24800	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GB849_RS24805	COG1388	LysM domain
GB849_RS24805	COG0791	NLP P60 protein
GB849_RS24810	COG1733	regulation of RNA biosynthetic process
GB849_RS24815	COG1307	EDD domain protein, DegV family
GB849_RS24820	COG1739	Uncharacterized protein family UPF0029
GB849_RS24825	COG1316	TRANSCRIPTIONal
GB849_RS24830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GB849_RS24835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GB849_RS24840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GB849_RS24850	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GB849_RS24850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GB849_RS24885	COG1486	melibiose metabolic process
GB849_RS24890	COG1447	Phosphotransferase system cellobiose-specific component IIA
GB849_RS24895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GB849_RS24905	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GB849_RS24925	COG1447	Phosphotransferase system cellobiose-specific component IIA
GB849_RS24935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GB849_RS24940	COG1301	dicarboxylic acid transport
GB849_RS24950	COG0346	lactoylglutathione lyase activity
GB849_RS24970	COG1511	domain protein
GB849_RS24975	COG0583	DNA-binding transcription factor activity
GB849_RS24980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GB849_RS24985	COG1271	oxidase subunit
GB849_RS24990	COG1294	oxidase, subunit
GB849_RS24995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GB849_RS25005	COG1620	l-lactate permease
GB849_RS25015	COG2389	metal-binding protein
GB849_RS25025	COG1368	sulfuric ester hydrolase activity
GB849_RS25035	COG1388	LysM domain
GB849_RS25035	COG0791	NLP P60 protein
GB849_RS25040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GB849_RS25050	COG1215	transferase activity, transferring glycosyl groups
GB849_RS25055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GB849_RS25060	COG3584	3D domain protein
GB849_RS25060	COG1388	LysM domain
GB849_RS25085	COG4715	Zinc finger, swim domain protein
GB849_RS25090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GB849_RS25130	COG0577	efflux transmembrane transporter activity
GB849_RS25135	COG1136	(ABC) transporter
GB849_RS25160	COG3850	Histidine kinase
GB849_RS25160	COG5002	protein histidine kinase activity
GB849_RS25165	COG0745	RESPONSE REGULATOR receiver
GB849_RS25170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GB849_RS25180	COG1316	TRANSCRIPTIONal
GB849_RS25185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GB849_RS25190	COG1216	Glycosyl transferase, family 2
GB849_RS25200	COG0438	transferase activity, transferring glycosyl groups
GB849_RS25220	COG1086	Polysaccharide biosynthesis protein
GB849_RS25235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GB849_RS25240	COG1086	Polysaccharide biosynthesis protein
GB849_RS25245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GB849_RS25250	COG4464	protein tyrosine phosphatase activity
GB849_RS25255	COG0489	protein tyrosine kinase activity
GB849_RS25260	COG3944	biosynthesis protein
GB849_RS25265	COG0489	protein tyrosine kinase activity
GB849_RS25280	COG1609	Transcriptional regulator
GB849_RS25290	COG0739	heme binding
GB849_RS25305	COG3279	Response regulator of the LytR AlgR family
GB849_RS25310	COG2385	sporulation resulting in formation of a cellular spore
GB849_RS25325	COG4836	Membrane
GB849_RS25330	COG1007	ATP synthesis coupled electron transport
GB849_RS25335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GB849_RS25340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GB849_RS25350	COG0839	Belongs to the complex I subunit 6 family
GB849_RS25370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GB849_RS25385	COG3300	MHYT domain
GB849_RS25385	COG5001	Diguanylate cyclase
GB849_RS25440	COG0356	it plays a direct role in the translocation of protons across the membrane
GB849_RS25475	COG0698	ribose 5-phosphate isomerase
GB849_RS25485	COG2190	(PTS) system
GB849_RS25490	COG2259	Doxx family
GB849_RS25495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GB849_RS25510	COG0009	L-threonylcarbamoyladenylate synthase
GB849_RS25525	COG2890	protein-(glutamine-N5) methyltransferase activity
GB849_RS25545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GB849_RS25550	COG1494	fructose-1,6-bisphosphatase
GB849_RS25570	COG4821	SIS domain
GB849_RS25590	COG1960	acyl-CoA dehydrogenase activity
GB849_RS25595	COG1960	acyl-CoA dehydrogenase activity
GB849_RS25600	COG1250	3-hydroxyacyl-CoA dehydrogenase
GB849_RS25605	COG0183	Belongs to the thiolase family
GB849_RS25610	COG2181	nitrate reductase activity
GB849_RS25610	COG0247	lactate metabolic process
GB849_RS25615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS25625	COG5001	Diguanylate cyclase
GB849_RS25625	COG3300	MHYT domain
GB849_RS25645	COG2197	response regulator
GB849_RS25650	COG4585	Histidine kinase
GB849_RS25655	COG0842	Transport permease protein
GB849_RS25660	COG1131	(ABC) transporter
GB849_RS25665	COG0024	Methionine aminopeptidase
GB849_RS25675	COG2234	aminopeptidase activity
GB849_RS25695	COG1595	DNA-templated transcription, initiation
GB849_RS25705	COG4506	Protein conserved in bacteria
GB849_RS25710	COG1619	proteins homologs of microcin C7 resistance protein MccF
GB849_RS25735	COG2814	Major facilitator Superfamily
GB849_RS25740	COG0789	Transcriptional regulator
GB849_RS25745	COG0584	glycerophosphoryl diester phosphodiesterase
GB849_RS25750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GB849_RS25760	COG1994	Peptidase M50
GB849_RS25770	COG1078	dGTPase activity
GB849_RS25775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GB849_RS25780	COG1120	ATPase activity
GB849_RS25785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS25790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GB849_RS25810	COG0095	Lipoate-protein ligase
GB849_RS25815	COG0280	phosphate acetyltransferase
GB849_RS25830	COG3773	Cell wall hydrolase
GB849_RS25840	COG2363	Small membrane protein
GB849_RS25850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GB849_RS25860	COG0561	phosphatase activity
GB849_RS25865	COG2814	Major facilitator Superfamily
GB849_RS25875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GB849_RS25880	COG1131	(ABC) transporter
GB849_RS25885	COG2755	lipolytic protein G-D-S-L family
GB849_RS25890	COG1609	Transcriptional regulator
GB849_RS25900	COG0460	homoserine dehydrogenase
GB849_RS25910	COG2873	o-acetylhomoserine
GB849_RS25920	COG1011	Hydrolase
GB849_RS25925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GB849_RS25935	COG2197	response regulator
GB849_RS25940	COG4585	Histidine kinase
GB849_RS25940	COG2203	Gaf domain
GB849_RS25945	COG0351	phosphomethylpyrimidine kinase
GB849_RS25950	COG3706	GGDEF domain
GB849_RS25955	COG2879	small protein
GB849_RS25960	COG1966	Carbon starvation protein
GB849_RS25965	COG3279	Response regulator of the LytR AlgR family
GB849_RS25970	COG0477	Major facilitator Superfamily
GB849_RS25980	COG0438	transferase activity, transferring glycosyl groups
GB849_RS25995	COG0840	transmembrane signaling receptor activity
GB849_RS26005	COG1607	acyl-coa hydrolase
GB849_RS26010	COG1216	Glycosyl transferase, family 2
GB849_RS26025	COG1216	Glycosyl transferase, family 2
GB849_RS26040	COG0488	(ABC) transporter
GB849_RS26045	COG1309	transcriptional regulator
GB849_RS26050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GB849_RS26055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GB849_RS26055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GB849_RS26060	COG0628	permease
GB849_RS26075	COG3279	Response regulator of the LytR AlgR family
GB849_RS26080	COG3275	phosphorelay sensor kinase activity
GB849_RS26085	COG2814	Major facilitator Superfamily
GB849_RS26090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GB849_RS26095	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GB849_RS26100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GB849_RS26145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GB849_RS26155	COG1272	protein, Hemolysin III
GB849_RS26175	COG1164	Oligoendopeptidase f
GB849_RS26200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GB849_RS26240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GB849_RS26245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GB849_RS26250	COG4853	Protein conserved in bacteria
GB849_RS26255	COG4863	YycH protein
GB849_RS26260	COG5002	protein histidine kinase activity
GB849_RS26265	COG0745	RESPONSE REGULATOR receiver
GB849_RS26295	COG0305	Participates in initiation and elongation during chromosome replication
GB849_RS26305	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GB849_RS26310	COG4241	membrane
GB849_RS26320	COG0629	single-stranded DNA binding
GB849_RS26330	COG0012	GTP binding
GB849_RS26335	COG4481	Protein conserved in bacteria
GB849_RS26340	COG0668	transmembrane transport
GB849_RS26350	COG1475	DNA binding
GB849_RS26355	COG1192	Involved in chromosome partitioning
GB849_RS26380	COG1847	R3H domain protein
GB849_RS26385	COG0706	membrane insertase activity
GB849_RS26395	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GB849_RS26790	COG2311	Membrane
GB849_RS26820	COG0776	regulation of translation
GB849_RS26860	COG2002	toxin-antitoxin pair type II binding
GB849_RS26880	COG0747	negative chemotaxis
GB849_RS26885	COG4166	transmembrane transport
GB849_RS26895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GB849_RS26975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GB849_RS27070	COG0640	Transcriptional regulator
GB849_RS27110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GB849_RS27125	COG0494	nUDIX hydrolase
GB849_RS27130	COG2368	4-hydroxyphenylacetate
GB849_RS27135	COG1475	DNA binding
GB849_RS27140	COG1611	Belongs to the LOG family
GB849_RS27145	COG3238	Protein conserved in bacteria
GB849_RS27150	COG0167	dihydroorotate dehydrogenase activity
GB849_RS27165	COG0546	phosphoglycolate phosphatase activity