locus-tag	class	description
EVS87_RS00010	COG4463	regulation of RNA biosynthetic process
EVS87_RS00015	COG3880	PFAM UvrB UvrC protein
EVS87_RS00020	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EVS87_RS00025	COG0542	response to heat
EVS87_RS00030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EVS87_RS00035	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EVS87_RS00040	COG4956	integral membrane protein (PIN domain superfamily)
EVS87_RS00045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EVS87_RS00050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EVS87_RS00055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVS87_RS00060	COG1045	serine acetyltransferase
EVS87_RS00065	COG0215	cysteine-tRNA ligase activity
EVS87_RS00070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EVS87_RS00075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS87_RS00080	COG3688	RNA-binding protein containing a PIN domain
EVS87_RS00085	COG1595	DNA-templated transcription, initiation
EVS87_RS00090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_RS00095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS87_RS00100	COG0250	Participates in transcription elongation, termination and antitermination
EVS87_RS00110	COG0081	regulation of translation
EVS87_RS00115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EVS87_RS00120	COG0222	ribosome binding
EVS87_RS00125	COG2813	Specifically methylates the guanine in position
EVS87_RS00130	COG0085	RNA polymerase activity
EVS87_RS00135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVS87_RS00140	COG1358	cellular component organization or biogenesis
EVS87_RS00145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EVS87_RS00150	COG0049	tRNA binding
EVS87_RS00155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EVS87_RS00160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVS87_RS00165	COG0596	Alpha beta hydrolase
EVS87_RS00175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EVS87_RS00180	COG0088	Forms part of the polypeptide exit tunnel
EVS87_RS00185	COG0089	rRNA binding
EVS87_RS00190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EVS87_RS00195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EVS87_RS00200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EVS87_RS00205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EVS87_RS00210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EVS87_RS00215	COG0255	Belongs to the universal ribosomal protein uL29 family
EVS87_RS00220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EVS87_RS00225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EVS87_RS00230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EVS87_RS00235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EVS87_RS00240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVS87_RS00245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EVS87_RS00250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EVS87_RS00255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EVS87_RS00260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EVS87_RS00265	COG1841	ribosomal large subunit assembly
EVS87_RS00270	COG0200	Binds to the 23S rRNA
EVS87_RS00275	COG0201	protein transport
EVS87_RS00280	COG0563	adenylate kinase activity
EVS87_RS00285	COG0024	Methionine aminopeptidase
EVS87_RS00295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EVS87_RS00300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EVS87_RS00305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EVS87_RS00310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EVS87_RS00315	COG0202	RNA polymerase activity
EVS87_RS00320	COG0203	ribosomal protein L17
EVS87_RS00325	COG1122	ATPase activity
EVS87_RS00330	COG1122	ATPase activity
EVS87_RS00335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_RS00340	COG0101	tRNA pseudouridine synthase activity
EVS87_RS00345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EVS87_RS00350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EVS87_RS00355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_RS00385	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS00390	COG0489	protein tyrosine kinase activity
EVS87_RS00400	COG2194	sulfuric ester hydrolase activity
EVS87_RS00405	COG0726	polysaccharide deacetylase
EVS87_RS00435	COG0659	secondary active sulfate transmembrane transporter activity
EVS87_RS00440	COG0385	Bile acid
EVS87_RS00445	COG3876	Protein conserved in bacteria
EVS87_RS00450	COG1472	Belongs to the glycosyl hydrolase 3 family
EVS87_RS00455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EVS87_RS00460	COG1263	PTS System
EVS87_RS00460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS00465	COG1737	Transcriptional regulator
EVS87_RS00470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EVS87_RS00505	COG1595	DNA-templated transcription, initiation
EVS87_RS00510	COG5662	AntiSigma factor
EVS87_RS00515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EVS87_RS00520	COG4856	YbbR-like protein
EVS87_RS00525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS87_RS00530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EVS87_RS00550	COG1131	(ABC) transporter
EVS87_RS00560	COG0577	efflux transmembrane transporter activity
EVS87_RS00560	COG1136	(ABC) transporter
EVS87_RS00570	COG1695	Transcriptional regulator
EVS87_RS00580	COG1131	(ABC) transporter
EVS87_RS00590	COG1413	lyase activity
EVS87_RS00595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS00610	COG2311	Membrane
EVS87_RS00630	COG1476	TRANSCRIPTIONal
EVS87_RS00640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVS87_RS00645	COG2207	Transcriptional regulator
EVS87_RS00650	COG1309	transcriptional regulator
EVS87_RS00665	COG1113	amino acid transport
EVS87_RS00670	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_RS00675	COG2271	Major facilitator Superfamily
EVS87_RS00685	COG1331	Highly conserved protein containing a thioredoxin domain
EVS87_RS00700	COG0640	Transcriptional regulator
EVS87_RS00715	COG1937	Protein conserved in bacteria
EVS87_RS00720	COG2210	Belongs to the sulfur carrier protein TusA family
EVS87_RS00730	COG0425	Belongs to the sulfur carrier protein TusA family
EVS87_RS00730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_RS00735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_RS00735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS00740	COG0425	Belongs to the sulfur carrier protein TusA family
EVS87_RS00745	COG0730	response to heat
EVS87_RS00750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVS87_RS00755	COG2814	Major facilitator Superfamily
EVS87_RS00770	COG1846	Transcriptional regulator
EVS87_RS00780	COG1683	Conserved Protein
EVS87_RS00790	COG0656	L-ascorbic acid biosynthetic process
EVS87_RS00795	COG0371	Dehydrogenase
EVS87_RS00800	COG1054	Belongs to the UPF0176 family
EVS87_RS00805	COG0531	amino acid
EVS87_RS00815	COG3711	transcriptional antiterminator
EVS87_RS00820	COG2190	(PTS) system
EVS87_RS00820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS00820	COG1263	PTS System
EVS87_RS00825	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS00835	COG1271	oxidase subunit
EVS87_RS00840	COG1294	oxidase, subunit
EVS87_RS00845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EVS87_RS00850	COG4988	ABC transporter
EVS87_RS00860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS00860	COG3711	transcriptional antiterminator
EVS87_RS00865	COG1940	carbohydrate kinase activity
EVS87_RS00870	COG0383	alpha-mannosidase activity
EVS87_RS00875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS00880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS00885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS00885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS00890	COG1404	Belongs to the peptidase S8 family
EVS87_RS00905	COG0833	amino acid
EVS87_RS00910	COG2040	homocysteine
EVS87_RS00915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_RS00925	COG1695	Transcriptional regulator
EVS87_RS00935	COG2814	Major facilitator Superfamily
EVS87_RS00940	COG0456	acetyltransferase
EVS87_RS00955	COG1404	Belongs to the peptidase S8 family
EVS87_RS00965	COG1309	transcriptional regulator
EVS87_RS00970	COG1917	Cupin 2, conserved barrel domain protein
EVS87_RS00980	COG0601	transmembrane transport
EVS87_RS00990	COG4172	Belongs to the ABC transporter superfamily
EVS87_RS00995	COG2217	Heavy metal translocating P-type atpase
EVS87_RS01005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS01010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS01015	COG1120	ATPase activity
EVS87_RS01020	COG1846	Transcriptional regulator
EVS87_RS01025	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS01030	COG0531	amino acid
EVS87_RS01040	COG0596	Alpha beta hydrolase
EVS87_RS01045	COG1115	amino acid carrier protein
EVS87_RS01050	COG2066	Belongs to the glutaminase family
EVS87_RS01055	COG4191	Histidine kinase
EVS87_RS01060	COG0784	Response regulator, receiver
EVS87_RS01065	COG1405	negative regulation of cell septum assembly
EVS87_RS01065	COG3012	SEC-C Motif Domain Protein
EVS87_RS01075	COG0667	Aldo Keto reductase
EVS87_RS01080	COG3290	protein histidine kinase activity
EVS87_RS01085	COG3279	Response regulator of the LytR AlgR family
EVS87_RS01090	COG4555	ABC transporter
EVS87_RS01095	COG1668	transmembrane transport
EVS87_RS01115	COG3773	Cell wall hydrolase
EVS87_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS01130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS01135	COG2310	stress, protein
EVS87_RS01140	COG2310	stress, protein
EVS87_RS01145	COG2310	stress, protein
EVS87_RS01150	COG0861	Integral membrane protein TerC family
EVS87_RS01180	COG3853	Toxic anion resistance protein (TelA)
EVS87_RS01185	COG4175	Glycine betaine
EVS87_RS01185	COG0517	IMP dehydrogenase activity
EVS87_RS01190	COG4176	ABC-type proline glycine betaine transport system permease component
EVS87_RS01195	COG2113	Glycine betaine
EVS87_RS01210	COG1473	amidohydrolase
EVS87_RS01215	COG1288	antiporter activity
EVS87_RS01220	COG0039	L-malate dehydrogenase activity
EVS87_RS01225	COG1620	l-lactate permease
EVS87_RS01230	COG1609	Transcriptional regulator
EVS87_RS01235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_RS01240	COG0561	phosphatase activity
EVS87_RS01245	COG0673	inositol 2-dehydrogenase activity
EVS87_RS01250	COG0738	Major facilitator superfamily
EVS87_RS01255	COG1280	lysine exporter protein (LysE YggA)
EVS87_RS01270	COG3403	YqcI/YcgG family
EVS87_RS01275	COG1113	amino acid transport
EVS87_RS01280	COG3665	Urea carboxylase-associated protein
EVS87_RS01285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EVS87_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS01300	COG0710	3-dehydroquinate dehydratase activity
EVS87_RS01305	COG0028	Belongs to the TPP enzyme family
EVS87_RS01315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EVS87_RS01320	COG2271	Major facilitator Superfamily
EVS87_RS01335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EVS87_RS01340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EVS87_RS01350	COG0477	Major facilitator Superfamily
EVS87_RS01355	COG2226	methyltransferase
EVS87_RS01360	COG0583	DNA-binding transcription factor activity
EVS87_RS01370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS87_RS01375	COG3458	cephalosporin-C deacetylase activity
EVS87_RS01385	COG3541	Predicted nucleotidyltransferase
EVS87_RS01390	COG0506	proline dehydrogenase activity
EVS87_RS01395	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS01400	COG2508	Transcriptional regulator
EVS87_RS01405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EVS87_RS01410	COG0765	amino acid transport
EVS87_RS01415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS01425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EVS87_RS01430	COG1522	sequence-specific DNA binding
EVS87_RS01435	COG2746	aminoglycoside 3-N-acetyltransferase activity
EVS87_RS01445	COG3290	protein histidine kinase activity
EVS87_RS01445	COG0840	transmembrane signaling receptor activity
EVS87_RS01450	COG3209	COG3209 Rhs family protein
EVS87_RS01475	COG3842	ATPase activity
EVS87_RS01480	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS87_RS01490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_RS01495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_RS01500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_RS01515	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EVS87_RS01520	COG0697	spore germination
EVS87_RS01525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_RS01535	COG2207	Transcriptional regulator
EVS87_RS01535	COG3708	Transcriptional regulator
EVS87_RS01545	COG2364	Membrane
EVS87_RS01550	COG0737	Belongs to the 5'-nucleotidase family
EVS87_RS01555	COG3764	Sortase (surface protein transpeptidase)
EVS87_RS01560	COG2002	toxin-antitoxin pair type II binding
EVS87_RS01565	COG1126	abc transporter atp-binding protein
EVS87_RS01570	COG0765	amino acid transport
EVS87_RS01575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS01580	COG0412	Dienelactone hydrolase
EVS87_RS01585	COG0833	amino acid
EVS87_RS01590	COG3104	oligopeptide transport
EVS87_RS01595	COG5434	Belongs to the glycosyl hydrolase 28 family
EVS87_RS01600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS01605	COG0456	acetyltransferase
EVS87_RS01610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS01615	COG0765	amino acid transport
EVS87_RS01620	COG1126	abc transporter atp-binding protein
EVS87_RS01625	COG1473	amidohydrolase
EVS87_RS01630	COG2079	MmgE PrpD family protein
EVS87_RS01640	COG0745	RESPONSE REGULATOR receiver
EVS87_RS01645	COG5002	protein histidine kinase activity
EVS87_RS01645	COG3850	Histidine kinase
EVS87_RS01655	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS01660	COG0527	aspartate kinase activity
EVS87_RS01665	COG2814	Major facilitator Superfamily
EVS87_RS01670	COG1309	transcriptional regulator
EVS87_RS01680	COG0640	Transcriptional regulator
EVS87_RS01685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_RS01690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVS87_RS01695	COG0531	amino acid
EVS87_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS01705	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_RS01710	COG4549	nuclear export factor GLE1
EVS87_RS01715	COG2372	response to copper ion
EVS87_RS01715	COG1276	copper resistance
EVS87_RS01720	COG2213	PTS system mannitol-specific
EVS87_RS01725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS01730	COG0246	Mannitol dehydrogenase
EVS87_RS01735	COG0840	transmembrane signaling receptor activity
EVS87_RS01770	COG0346	lactoylglutathione lyase activity
EVS87_RS01780	COG0561	phosphatase activity
EVS87_RS01785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EVS87_RS01790	COG1914	H( )-stimulated, divalent metal cation uptake system
EVS87_RS01795	COG4336	lyase activity
EVS87_RS01800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EVS87_RS01805	COG1984	allophanate hydrolase subunit 2
EVS87_RS01810	COG1414	Transcriptional regulator
EVS87_RS01815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_RS01820	COG2755	lipolytic protein G-D-S-L family
EVS87_RS01830	COG3711	transcriptional antiterminator
EVS87_RS01835	COG2226	methyltransferase
EVS87_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS01845	COG3871	stress protein (general stress protein 26)
EVS87_RS01865	COG2814	Major facilitator Superfamily
EVS87_RS01870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVS87_RS01870	COG0551	DNA topoisomerase type I activity
EVS87_RS01875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EVS87_RS01880	COG3706	GGDEF domain
EVS87_RS01885	COG5298	Protein conserved in bacteria
EVS87_RS01890	COG1215	transferase activity, transferring glycosyl groups
EVS87_RS01900	COG0531	amino acid
EVS87_RS01905	COG0028	Belongs to the TPP enzyme family
EVS87_RS01925	COG5444	nuclease activity
EVS87_RS01955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_RS01960	COG1914	H( )-stimulated, divalent metal cation uptake system
EVS87_RS01965	COG2261	transglycosylase associated protein
EVS87_RS01970	COG2217	Heavy metal translocating P-type atpase
EVS87_RS01975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EVS87_RS01980	COG3290	protein histidine kinase activity
EVS87_RS01985	COG4565	transcriptional regulatory protein
EVS87_RS01990	COG1301	dicarboxylic acid transport
EVS87_RS01995	COG0628	permease
EVS87_RS02000	COG1301	dicarboxylic acid transport
EVS87_RS02005	COG1131	(ABC) transporter
EVS87_RS02010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EVS87_RS02025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS02030	COG1181	Belongs to the D-alanine--D-alanine ligase family
EVS87_RS02035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EVS87_RS02050	COG0513	Belongs to the DEAD box helicase family
EVS87_RS02055	COG3402	PFAM membrane-flanked domain
EVS87_RS02060	COG3428	Bacterial PH domain
EVS87_RS02065	COG0705	Rhomboid family
EVS87_RS02070	COG0736	holo-[acyl-carrier-protein] synthase activity
EVS87_RS02075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EVS87_RS02080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVS87_RS02085	COG0864	Transcriptional regulator
EVS87_RS02090	COG2337	Toxic component of a toxin-antitoxin (TA) module
EVS87_RS02095	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS02100	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS02105	COG2172	sigma factor antagonist activity
EVS87_RS02110	COG2208	phosphoserine phosphatase activity
EVS87_RS02115	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS02120	COG2172	sigma factor antagonist activity
EVS87_RS02125	COG1191	sigma factor activity
EVS87_RS02130	COG2208	phosphoserine phosphatase activity
EVS87_RS02135	COG2183	response to ionizing radiation
EVS87_RS02145	COG3091	SprT-like family
EVS87_RS02150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_RS02155	COG0022	dehydrogenase e1 component
EVS87_RS02160	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS02165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_RS02170	COG3284	Transcriptional regulator
EVS87_RS02225	COG1278	Cold shock
EVS87_RS02230	COG1329	Transcriptional regulator
EVS87_RS02235	COG1064	alcohol dehydrogenase
EVS87_RS02240	COG0789	Transcriptional regulator
EVS87_RS02255	COG0477	Major facilitator Superfamily
EVS87_RS02260	COG0657	acetylesterase activity
EVS87_RS02270	COG4221	oxidoreductase activity
EVS87_RS02280	COG0252	asparaginase activity
EVS87_RS02305	COG2814	Major facilitator Superfamily
EVS87_RS02310	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EVS87_RS02315	COG2409	Drug exporters of the RND superfamily
EVS87_RS02320	COG4585	Histidine kinase
EVS87_RS02325	COG2197	response regulator
EVS87_RS02370	COG1309	transcriptional regulator
EVS87_RS02375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EVS87_RS02380	COG1846	Transcriptional regulator
EVS87_RS02385	COG0778	Nitroreductase
EVS87_RS02400	COG1396	sequence-specific DNA binding
EVS87_RS02410	COG0456	acetyltransferase
EVS87_RS02420	COG4122	O-methyltransferase activity
EVS87_RS02430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EVS87_RS02435	COG0697	spore germination
EVS87_RS02445	COG1301	dicarboxylic acid transport
EVS87_RS02485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EVS87_RS02490	COG0802	atpase or kinase
EVS87_RS02495	COG1214	PFAM Peptidase M22, glycoprotease
EVS87_RS02500	COG0456	acetyltransferase
EVS87_RS02505	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EVS87_RS02510	COG0488	(ABC) transporter
EVS87_RS02515	COG0315	cyclic pyranopterin monophosphate synthase activity
EVS87_RS02520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EVS87_RS02525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVS87_RS02530	COG0805	protein transport
EVS87_RS02545	COG1266	CAAX protease self-immunity
EVS87_RS02550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EVS87_RS02555	COG0459	protein refolding
EVS87_RS02565	COG2856	Zn peptidase
EVS87_RS02575	COG3620	sequence-specific DNA binding
EVS87_RS02590	COG3645	SOS response
EVS87_RS02590	COG3646	Phage regulatory protein
EVS87_RS02610	COG5377	YqaJ viral recombinase family
EVS87_RS02615	COG3723	Recombinational DNA repair protein, rece pathway
EVS87_RS02630	COG1484	DNA-dependent DNA replication
EVS87_RS02695	COG1595	DNA-templated transcription, initiation
EVS87_RS02700	COG3677	Transposase
EVS87_RS02710	COG5484	DNA packaging
EVS87_RS02845	COG1846	Transcriptional regulator
EVS87_RS02850	COG0456	acetyltransferase
EVS87_RS02855	COG2808	Putative FMN-binding domain
EVS87_RS02860	COG1876	peptidase activity
EVS87_RS02885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EVS87_RS02890	COG0823	Involved in the tonB-independent uptake of proteins
EVS87_RS02900	COG2132	Multicopper oxidase
EVS87_RS02905	COG1113	amino acid transport
EVS87_RS02910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EVS87_RS02915	COG0714	Associated with various cellular activities
EVS87_RS02920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EVS87_RS02925	COG1305	Transglutaminase-like
EVS87_RS02930	COG0519	Catalyzes the synthesis of GMP from XMP
EVS87_RS02930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EVS87_RS02950	COG3279	Response regulator of the LytR AlgR family
EVS87_RS02965	COG1595	DNA-templated transcription, initiation
EVS87_RS02975	COG2814	Major facilitator Superfamily
EVS87_RS02980	COG0583	DNA-binding transcription factor activity
EVS87_RS02985	COG2252	PERMEase
EVS87_RS02990	COG5583	Uncharacterized small protein (DUF2292)
EVS87_RS03005	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EVS87_RS03015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EVS87_RS03020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EVS87_RS03025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EVS87_RS03030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EVS87_RS03035	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVS87_RS03040	COG0047	phosphoribosylformylglycinamidine synthase activity
EVS87_RS03045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVS87_RS03050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EVS87_RS03055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EVS87_RS03060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EVS87_RS03065	COG0138	bifunctional purine biosynthesis protein purh
EVS87_RS03070	COG0151	Belongs to the GarS family
EVS87_RS03090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS87_RS03095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EVS87_RS03100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVS87_RS03105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS87_RS03115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EVS87_RS03120	COG4496	protein, YerC YecD
EVS87_RS03130	COG0069	glutamate synthase activity
EVS87_RS03145	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EVS87_RS03150	COG0210	DNA helicase
EVS87_RS03155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVS87_RS03160	COG4851	CamS sex pheromone cAM373 precursor
EVS87_RS03170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_RS03175	COG1285	pathogenesis
EVS87_RS03180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_RS03185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS87_RS03190	COG0154	amidase activity
EVS87_RS03195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS87_RS03200	COG1309	transcriptional regulator
EVS87_RS03205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS87_RS03215	COG1957	nucleoside hydrolase
EVS87_RS03220	COG1597	lipid kinase activity
EVS87_RS03225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS87_RS03235	COG5444	nuclease activity
EVS87_RS03240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVS87_RS03255	COG1959	2 iron, 2 sulfur cluster binding
EVS87_RS03260	COG0492	ferredoxin-NADP+ reductase activity
EVS87_RS03275	COG1486	melibiose metabolic process
EVS87_RS03285	COG2211	Major facilitator Superfamily
EVS87_RS03325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EVS87_RS03330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_RS03335	COG1442	glycosyl transferase family 8
EVS87_RS03340	COG1216	Glycosyl transferase, family 2
EVS87_RS03345	COG1442	glycosyl transferase family 8
EVS87_RS03350	COG2223	nitrite transmembrane transporter activity
EVS87_RS03360	COG0471	metal ion transport
EVS87_RS03375	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_RS03390	COG0531	amino acid
EVS87_RS03395	COG0463	Glycosyl transferase, family 2
EVS87_RS03395	COG0457	Tetratricopeptide repeat
EVS87_RS03400	COG0488	(ABC) transporter
EVS87_RS03405	COG1469	GTP cyclohydrolase I activity
EVS87_RS03410	COG0789	Transcriptional regulator
EVS87_RS03415	COG2814	Major facilitator Superfamily
EVS87_RS03420	COG0488	(ABC) transporter
EVS87_RS03425	COG0513	Belongs to the DEAD box helicase family
EVS87_RS03430	COG2130	NADP-dependent
EVS87_RS03450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS03450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS03455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EVS87_RS03465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_RS03465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_RS03475	COG3290	protein histidine kinase activity
EVS87_RS03480	COG4565	transcriptional regulatory protein
EVS87_RS03485	COG3181	Tripartite tricarboxylate transporter family receptor
EVS87_RS03490	COG2851	Citrate transporter
EVS87_RS03500	COG3479	Phenolic acid decarboxylase
EVS87_RS03505	COG1695	Transcriptional regulator
EVS87_RS03510	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EVS87_RS03520	COG1254	Belongs to the acylphosphatase family
EVS87_RS03525	COG2258	MOSC domain
EVS87_RS03535	COG0024	Methionine aminopeptidase
EVS87_RS03540	COG1263	PTS System
EVS87_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS03545	COG3739	integral membrane protein
EVS87_RS03560	COG1368	sulfuric ester hydrolase activity
EVS87_RS03565	COG0076	glutamate decarboxylase activity
EVS87_RS03570	COG0840	transmembrane signaling receptor activity
EVS87_RS03580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS03580	COG1263	PTS System
EVS87_RS03585	COG0366	Alpha amylase catalytic
EVS87_RS03590	COG2188	Transcriptional regulator
EVS87_RS03600	COG0737	Belongs to the 5'-nucleotidase family
EVS87_RS03605	COG0693	protein deglycase activity
EVS87_RS03610	COG4840	Belongs to the UPF0435 family
EVS87_RS03615	COG1115	amino acid carrier protein
EVS87_RS03625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS87_RS03630	COG4980	gas vesicle protein
EVS87_RS03635	COG1295	ribonuclease BN
EVS87_RS03640	COG0477	Major facilitator Superfamily
EVS87_RS03650	COG0387	Pfam Sodium calcium exchanger
EVS87_RS03665	COG4152	abc transporter atp-binding protein
EVS87_RS03690	COG0217	transcriptional regulatory protein
EVS87_RS03700	COG0668	transmembrane transport
EVS87_RS03705	COG0535	radical SAM domain protein
EVS87_RS03715	COG0726	polysaccharide deacetylase
EVS87_RS03725	COG0598	Magnesium transport protein CorA
EVS87_RS03735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EVS87_RS03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS87_RS03755	COG0789	Transcriptional regulator
EVS87_RS03760	COG2814	Major facilitator Superfamily
EVS87_RS03810	COG2076	Multidrug Resistance protein
EVS87_RS03815	COG2076	Multidrug Resistance protein
EVS87_RS03820	COG1309	transcriptional regulator
EVS87_RS03830	COG4637	Psort location Cytoplasmic, score
EVS87_RS03835	COG2755	lipolytic protein G-D-S-L family
EVS87_RS03840	COG0492	ferredoxin-NADP+ reductase activity
EVS87_RS03845	COG2169	Transcriptional regulator
EVS87_RS03850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EVS87_RS03855	COG1132	(ABC) transporter
EVS87_RS03860	COG1742	UPF0060 membrane protein
EVS87_RS03865	COG1595	DNA-templated transcription, initiation
EVS87_RS03885	COG2318	DinB family
EVS87_RS03895	COG1846	Transcriptional regulator
EVS87_RS03900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EVS87_RS03900	COG0392	lysyltransferase activity
EVS87_RS03920	COG0778	Nitroreductase
EVS87_RS03935	COG1090	epimerase
EVS87_RS03940	COG2137	regulation of response to DNA damage stimulus
EVS87_RS03965	COG0463	Glycosyl transferase, family 2
EVS87_RS03970	COG4485	Bacterial membrane protein, YfhO
EVS87_RS03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVS87_RS03990	COG2140	Oxalate decarboxylase
EVS87_RS04000	COG1191	sigma factor activity
EVS87_RS04045	COG1988	membrane-bound metal-dependent
EVS87_RS04050	COG1194	a g-specific adenine glycosylase
EVS87_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS04075	COG3557	Belongs to the UPF0374 family
EVS87_RS04080	COG1132	(ABC) transporter
EVS87_RS04085	COG0444	Belongs to the ABC transporter superfamily
EVS87_RS04090	COG4608	Belongs to the ABC transporter superfamily
EVS87_RS04095	COG0747	negative chemotaxis
EVS87_RS04100	COG0601	transmembrane transport
EVS87_RS04105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS04110	COG4129	membrane
EVS87_RS04115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS87_RS04120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVS87_RS04125	COG0735	belongs to the Fur family
EVS87_RS04275	COG1368	sulfuric ester hydrolase activity
EVS87_RS04280	COG0681	Belongs to the peptidase S26 family
EVS87_RS04285	COG2873	o-acetylhomoserine
EVS87_RS04295	COG1116	anion transmembrane transporter activity
EVS87_RS04300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS87_RS04305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS87_RS04320	COG1131	(ABC) transporter
EVS87_RS04350	COG3382	B3 4 domain protein
EVS87_RS04355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EVS87_RS04365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EVS87_RS04370	COG2766	serine protein kinase
EVS87_RS04375	COG2718	Belongs to the UPF0229 family
EVS87_RS04380	COG1566	PFAM secretion protein HlyD family protein
EVS87_RS04385	COG2814	Major facilitator Superfamily
EVS87_RS04390	COG0655	NAD(P)H dehydrogenase (quinone) activity
EVS87_RS04400	COG1278	Cold shock
EVS87_RS04410	COG3706	GGDEF domain
EVS87_RS04435	COG5577	PFAM Coat F domain
EVS87_RS04440	COG5002	protein histidine kinase activity
EVS87_RS04445	COG4085	toxin activity
EVS87_RS04445	COG1525	nuclease
EVS87_RS04445	COG0737	Belongs to the 5'-nucleotidase family
EVS87_RS04450	COG3764	Sortase (surface protein transpeptidase)
EVS87_RS04455	COG0564	pseudouridine synthase activity
EVS87_RS04465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EVS87_RS04470	COG3153	acetyltransferase
EVS87_RS04470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS87_RS04490	COG3835	regulator
EVS87_RS04495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS87_RS04500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EVS87_RS04505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EVS87_RS04510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EVS87_RS04515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EVS87_RS04520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS87_RS04525	COG4585	Histidine kinase
EVS87_RS04525	COG2203	Gaf domain
EVS87_RS04530	COG2197	response regulator
EVS87_RS04545	COG0753	catalase activity
EVS87_RS04550	COG1959	2 iron, 2 sulfur cluster binding
EVS87_RS04555	COG1017	nitric oxide dioxygenase activity
EVS87_RS04555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVS87_RS04560	COG2719	SpoVR family
EVS87_RS04565	COG1785	Belongs to the alkaline phosphatase family
EVS87_RS04570	COG1388	LysM domain
EVS87_RS04570	COG0791	NLP P60 protein
EVS87_RS04575	COG0531	amino acid
EVS87_RS04590	COG1595	DNA-templated transcription, initiation
EVS87_RS04595	COG0204	Acyl-transferase
EVS87_RS04600	COG1253	flavin adenine dinucleotide binding
EVS87_RS04605	COG0789	Transcriptional regulator
EVS87_RS04610	COG1253	flavin adenine dinucleotide binding
EVS87_RS04625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVS87_RS04630	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_RS04640	COG0668	transmembrane transport
EVS87_RS04645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EVS87_RS04650	COG0726	polysaccharide deacetylase
EVS87_RS04655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_RS04660	COG0589	response to stress
EVS87_RS04665	COG1132	(ABC) transporter
EVS87_RS04670	COG1132	(ABC) transporter
EVS87_RS04680	COG0702	epimerase
EVS87_RS04690	COG3842	ATPase activity
EVS87_RS04695	COG2508	Transcriptional regulator
EVS87_RS04705	COG0189	ligase activity
EVS87_RS04710	COG0189	ligase activity
EVS87_RS04715	COG4399	Belongs to the UPF0754 family
EVS87_RS04720	COG3679	Belongs to the UPF0342 family
EVS87_RS04725	COG0561	phosphatase activity
EVS87_RS04730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVS87_RS04740	COG0475	glutathione-regulated potassium exporter activity
EVS87_RS04745	COG0490	domain, Protein
EVS87_RS04755	COG1024	Enoyl-CoA hydratase
EVS87_RS04765	COG0420	3'-5' exonuclease activity
EVS87_RS04770	COG4717	serine-type aminopeptidase activity
EVS87_RS04775	COG3481	metal-dependent phosphohydrolase, HD sub domain
EVS87_RS04785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVS87_RS04815	COG1846	Transcriptional regulator
EVS87_RS04820	COG4980	gas vesicle protein
EVS87_RS04835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EVS87_RS04840	COG0537	adenosine 5'-monophosphoramidase activity
EVS87_RS04845	COG1131	(ABC) transporter
EVS87_RS04850	COG4473	ABC transporter
EVS87_RS04860	COG1473	amidohydrolase
EVS87_RS04870	COG2329	Antibiotic biosynthesis monooxygenase
EVS87_RS04875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_RS04880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EVS87_RS04885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVS87_RS04890	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EVS87_RS04895	COG1309	transcriptional regulator
EVS87_RS04900	COG1511	domain protein
EVS87_RS04905	COG1363	Peptidase, m42
EVS87_RS04910	COG1301	dicarboxylic acid transport
EVS87_RS04920	COG1234	tRNA 3'-trailer cleavage
EVS87_RS04925	COG0095	Lipoate-protein ligase
EVS87_RS04930	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS04940	COG0501	Belongs to the peptidase M48B family
EVS87_RS04945	COG1404	Belongs to the peptidase S8 family
EVS87_RS04950	COG0406	alpha-ribazole phosphatase activity
EVS87_RS04955	COG0840	transmembrane signaling receptor activity
EVS87_RS04960	COG0723	plastoquinol--plastocyanin reductase activity
EVS87_RS04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVS87_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS04975	COG4903	ComK protein
EVS87_RS04980	COG4974	Belongs to the 'phage' integrase family
EVS87_RS04985	COG2856	Zn peptidase
EVS87_RS04995	COG1396	sequence-specific DNA binding
EVS87_RS05010	COG3645	SOS response
EVS87_RS05010	COG3646	Phage regulatory protein
EVS87_RS05030	COG5377	YqaJ viral recombinase family
EVS87_RS05035	COG3723	Recombinational DNA repair protein, rece pathway
EVS87_RS05050	COG1484	DNA-dependent DNA replication
EVS87_RS05055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_RS05090	COG3677	Transposase
EVS87_RS05100	COG5484	DNA packaging
EVS87_RS05170	COG3953	SLT domain
EVS87_RS05170	COG5412	phage tail tape measure protein
EVS87_RS05235	COG1876	peptidase activity
EVS87_RS05290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_RS05295	COG2814	Major facilitator Superfamily
EVS87_RS05300	COG2732	(Barnase) inhibitor
EVS87_RS05305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS05310	COG4605	iron ion homeostasis
EVS87_RS05315	COG4604	ABC transporter, ATP-binding protein
EVS87_RS05320	COG4607	ABC-type enterochelin transport system periplasmic component
EVS87_RS05325	COG1316	TRANSCRIPTIONal
EVS87_RS05345	COG0398	Pfam SNARE associated Golgi protein
EVS87_RS05350	COG0681	Belongs to the peptidase S26 family
EVS87_RS05355	COG3180	Ammonia monooxygenase
EVS87_RS05370	COG2259	Doxx family
EVS87_RS05375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EVS87_RS05380	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EVS87_RS05385	COG1074	ATP-dependent DNA helicase activity
EVS87_RS05390	COG0420	3'-5' exonuclease activity
EVS87_RS05395	COG0419	ATPase involved in DNA repair
EVS87_RS05400	COG1403	HNH endonuclease
EVS87_RS05440	COG5337	Spore coat protein CotH
EVS87_RS05455	COG0179	Fumarylacetoacetate (FAA) hydrolase
EVS87_RS05470	COG0367	asparagine synthase
EVS87_RS05485	COG1562	ergosterol biosynthetic process
EVS87_RS05490	COG0534	Mate efflux family protein
EVS87_RS05495	COG1917	Cupin 2, conserved barrel domain protein
EVS87_RS05495	COG2207	Transcriptional regulator
EVS87_RS05520	COG0076	glutamate decarboxylase activity
EVS87_RS05555	COG1410	methionine synthase
EVS87_RS05555	COG0646	methionine synthase
EVS87_RS05560	COG0646	methionine synthase
EVS87_RS05560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EVS87_RS05565	COG1666	GTP binding
EVS87_RS05570	COG2996	Protein conserved in bacteria
EVS87_RS05575	COG1744	ABC transporter substrate-binding protein PnrA-like
EVS87_RS05580	COG0840	transmembrane signaling receptor activity
EVS87_RS05585	COG1307	EDD domain protein, DegV family
EVS87_RS05590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_RS05610	COG0561	phosphatase activity
EVS87_RS05615	COG1073	alpha beta
EVS87_RS05620	COG2151	metal-sulfur cluster biosynthetic enzyme
EVS87_RS05625	COG0277	FAD linked oxidase domain protein
EVS87_RS05630	COG2271	Major facilitator Superfamily
EVS87_RS05635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EVS87_RS05640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EVS87_RS05645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVS87_RS05650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVS87_RS05655	COG0505	Belongs to the CarA family
EVS87_RS05660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVS87_RS05665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EVS87_RS05675	COG2814	Major facilitator Superfamily
EVS87_RS05685	COG2267	carboxylic ester hydrolase activity
EVS87_RS05695	COG1744	ABC transporter substrate-binding protein PnrA-like
EVS87_RS05710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVS87_RS05715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EVS87_RS05720	COG5504	Zn-dependent protease
EVS87_RS05725	COG0444	Belongs to the ABC transporter superfamily
EVS87_RS05730	COG4608	Belongs to the ABC transporter superfamily
EVS87_RS05740	COG0601	transmembrane transport
EVS87_RS05745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS05755	COG0180	Tryptophanyl-tRNA synthetase
EVS87_RS05765	COG4166	transmembrane transport
EVS87_RS05770	COG0601	transmembrane transport
EVS87_RS05775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS05780	COG0444	Belongs to the ABC transporter superfamily
EVS87_RS05785	COG4608	Belongs to the ABC transporter superfamily
EVS87_RS05795	COG0456	acetyltransferase
EVS87_RS05800	COG1393	Belongs to the ArsC family
EVS87_RS05805	COG0861	Integral membrane protein TerC family
EVS87_RS05810	COG4862	establishment of competence for transformation
EVS87_RS05815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_RS05825	COG1164	Oligoendopeptidase f
EVS87_RS05835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EVS87_RS05840	COG2346	COG2346, Truncated hemoglobins
EVS87_RS05845	COG0741	lytic transglycosylase activity
EVS87_RS05850	COG4116	CYTH
EVS87_RS05860	COG2357	RelA SpoT domain protein
EVS87_RS05865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVS87_RS05870	COG0564	pseudouridine synthase activity
EVS87_RS05875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EVS87_RS05880	COG0569	domain protein
EVS87_RS05880	COG0475	glutathione-regulated potassium exporter activity
EVS87_RS05885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVS87_RS05890	COG0352	thiamine-phosphate diphosphorylase activity
EVS87_RS05900	COG2104	thiamine diphosphate biosynthetic process
EVS87_RS05905	COG2022	thiamine diphosphate biosynthetic process
EVS87_RS05910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVS87_RS05915	COG0351	phosphomethylpyrimidine kinase
EVS87_RS05920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EVS87_RS05975	COG0210	DNA helicase
EVS87_RS05985	COG2153	protein acetylation
EVS87_RS05990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EVS87_RS05995	COG2382	esterase
EVS87_RS06000	COG0626	cystathionine gamma-synthase activity
EVS87_RS06005	COG0626	cystathionine gamma-synthase activity
EVS87_RS06015	COG0825	malonyl-CoA metabolic process
EVS87_RS06035	COG2807	transmembrane transport
EVS87_RS06045	COG0583	DNA-binding transcription factor activity
EVS87_RS06060	COG0457	Tetratricopeptide repeat
EVS87_RS06080	COG3173	Aminoglycoside phosphotransferase
EVS87_RS06085	COG0583	DNA-binding transcription factor activity
EVS87_RS06105	COG0583	DNA-binding transcription factor activity
EVS87_RS06110	COG2807	transmembrane transport
EVS87_RS06120	COG0457	Tetratricopeptide repeat
EVS87_RS06130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVS87_RS06140	COG1309	transcriptional regulator
EVS87_RS06150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_RS06155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_RS06175	COG4195	phage-related replication protein
EVS87_RS06180	COG2856	Zn peptidase
EVS87_RS06185	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS06185	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS06200	COG0306	phosphate transporter
EVS87_RS06205	COG1392	Phosphate transport regulator
EVS87_RS06215	COG0405	Gamma-glutamyltransferase
EVS87_RS06220	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EVS87_RS06230	COG4208	sulfate ABC transporter
EVS87_RS06235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EVS87_RS06245	COG3775	system Galactitol-specific IIC component
EVS87_RS06260	COG1063	alcohol dehydrogenase
EVS87_RS06265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_RS06270	COG0022	dehydrogenase e1 component
EVS87_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS06275	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS06280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS06290	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS06295	COG2390	Transcriptional regulator
EVS87_RS06305	COG0531	amino acid
EVS87_RS06310	COG0346	lactoylglutathione lyase activity
EVS87_RS06315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_RS06320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_RS06325	COG2362	D-Aminopeptidase
EVS87_RS06330	COG0601	transmembrane transport
EVS87_RS06335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS06340	COG0444	Belongs to the ABC transporter superfamily
EVS87_RS06345	COG4166	transmembrane transport
EVS87_RS06350	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_RS06355	COG4948	Mandelate Racemase Muconate Lactonizing
EVS87_RS06360	COG0791	NLP P60 protein
EVS87_RS06365	COG4608	Belongs to the ABC transporter superfamily
EVS87_RS06370	COG1834	amidinotransferase
EVS87_RS06375	COG1607	acyl-coa hydrolase
EVS87_RS06380	COG1695	Transcriptional regulator
EVS87_RS06395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_RS06405	COG2076	Multidrug Resistance protein
EVS87_RS06410	COG2076	Multidrug Resistance protein
EVS87_RS06420	COG0788	formyltetrahydrofolate deformylase activity
EVS87_RS06425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVS87_RS06430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVS87_RS06435	COG0457	Tetratricopeptide repeat
EVS87_RS06445	COG1764	response to oxidative stress
EVS87_RS06450	COG1846	Transcriptional regulator
EVS87_RS06455	COG1764	response to oxidative stress
EVS87_RS06460	COG0590	tRNA wobble adenosine to inosine editing
EVS87_RS06465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVS87_RS06470	COG1404	Belongs to the peptidase S8 family
EVS87_RS06485	COG0745	RESPONSE REGULATOR receiver
EVS87_RS06490	COG5002	protein histidine kinase activity
EVS87_RS06490	COG3850	Histidine kinase
EVS87_RS06495	COG3212	peptidase
EVS87_RS06500	COG3212	peptidase
EVS87_RS06510	COG2239	Acts as a magnesium transporter
EVS87_RS06520	COG0583	DNA-binding transcription factor activity
EVS87_RS06530	COG0789	Transcriptional regulator
EVS87_RS06540	COG1846	Transcriptional regulator
EVS87_RS06545	COG5001	Diguanylate cyclase
EVS87_RS06545	COG3300	MHYT domain
EVS87_RS06550	COG0586	Pfam SNARE associated Golgi protein
EVS87_RS06555	COG0861	Integral membrane protein TerC family
EVS87_RS06560	COG1191	sigma factor activity
EVS87_RS06580	COG0501	Belongs to the peptidase M48B family
EVS87_RS06585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EVS87_RS06590	COG2323	membrane
EVS87_RS06600	COG3594	Acyltransferase
EVS87_RS06605	COG5002	protein histidine kinase activity
EVS87_RS06610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EVS87_RS06615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EVS87_RS06620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EVS87_RS06625	COG0436	Aminotransferase
EVS87_RS06630	COG1850	ribulose-bisphosphate carboxylase activity
EVS87_RS06635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EVS87_RS06640	COG0235	Class ii aldolase
EVS87_RS06645	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EVS87_RS06655	COG3852	Histidine kinase
EVS87_RS06660	COG1846	Transcriptional regulator
EVS87_RS06665	COG1360	Flagellar Motor Protein
EVS87_RS06670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EVS87_RS06680	COG0542	response to heat
EVS87_RS06685	COG3949	Membrane
EVS87_RS06690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EVS87_RS06695	COG0720	synthase
EVS87_RS06700	COG0602	queuosine metabolic process
EVS87_RS06705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EVS87_RS06715	COG4873	Protein conserved in bacteria
EVS87_RS06725	COG3773	Cell wall hydrolase
EVS87_RS06730	COG2244	polysaccharide biosynthetic process
EVS87_RS06735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS06740	COG2217	Heavy metal translocating P-type atpase
EVS87_RS06745	COG0006	proline dipeptidase activity
EVS87_RS06750	COG1609	Transcriptional regulator
EVS87_RS06755	COG3711	transcriptional antiterminator
EVS87_RS06760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS06760	COG1263	PTS System
EVS87_RS06760	COG2190	(PTS) system
EVS87_RS06765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS06770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EVS87_RS06780	COG1533	DNA photolyase activity
EVS87_RS06785	COG0840	transmembrane signaling receptor activity
EVS87_RS06795	COG2084	Dehydrogenase
EVS87_RS06800	COG2340	Cysteine-rich secretory protein family
EVS87_RS06805	COG0768	penicillin binding
EVS87_RS06810	COG4191	Histidine kinase
EVS87_RS06815	COG0436	Aminotransferase
EVS87_RS06820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EVS87_RS06825	COG1714	RDD family
EVS87_RS06835	COG0784	Response regulator, receiver
EVS87_RS06835	COG0835	chemotaxis
EVS87_RS06850	COG2814	Major facilitator Superfamily
EVS87_RS06855	COG1376	ErfK ybiS ycfS ynhG family protein
EVS87_RS06860	COG1408	metallophosphoesterase
EVS87_RS06865	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS06870	COG2200	EAL domain
EVS87_RS06875	COG3546	catalase activity
EVS87_RS06880	COG4703	Protein of unknown function (DUF1797)
EVS87_RS06885	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EVS87_RS06895	COG0517	IMP dehydrogenase activity
EVS87_RS06900	COG0583	DNA-binding transcription factor activity
EVS87_RS06910	COG0716	FMN binding
EVS87_RS06920	COG0716	FMN binding
EVS87_RS06925	COG2171	N-acyltransferase activity
EVS87_RS06930	COG1473	amidohydrolase
EVS87_RS06940	COG0668	transmembrane transport
EVS87_RS06945	COG0450	alkyl hydroperoxide reductase
EVS87_RS06950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS06965	COG0746	molybdenum cofactor guanylyltransferase activity
EVS87_RS06970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVS87_RS06975	COG0303	'Molybdopterin
EVS87_RS06980	COG1763	Mo-molybdopterin cofactor biosynthetic process
EVS87_RS06985	COG0314	molybdopterin synthase activity
EVS87_RS06990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EVS87_RS07005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVS87_RS07010	COG1136	(ABC) transporter
EVS87_RS07015	COG0577	efflux transmembrane transporter activity
EVS87_RS07020	COG1349	DNA-binding transcription factor activity
EVS87_RS07025	COG1105	Belongs to the carbohydrate kinase PfkB family
EVS87_RS07030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS07030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS07030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS07035	COG0681	Belongs to the peptidase S26 family
EVS87_RS07045	COG0488	(ABC) transporter
EVS87_RS07050	COG2309	aminopeptidase activity
EVS87_RS07055	COG1077	Cell shape determining protein MreB Mrl
EVS87_RS07060	COG2002	toxin-antitoxin pair type II binding
EVS87_RS07065	COG3852	Histidine kinase
EVS87_RS07070	COG2105	PFAM AIG2 family protein
EVS87_RS07070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EVS87_RS07075	COG0569	domain protein
EVS87_RS07080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EVS87_RS07085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVS87_RS07090	COG5503	Protein of unknown function (DUF1447)
EVS87_RS07095	COG0561	phosphatase activity
EVS87_RS07100	COG0242	peptide deformylase activity
EVS87_RS07115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_RS07120	COG0022	dehydrogenase e1 component
EVS87_RS07125	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS07130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_RS07140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS07150	COG1982	Orn Lys Arg decarboxylase major
EVS87_RS07155	COG4476	Belongs to the UPF0223 family
EVS87_RS07160	COG4493	Belongs to the UPF0637 family
EVS87_RS07170	COG0483	inositol monophosphate 1-phosphatase activity
EVS87_RS07185	COG1595	DNA-templated transcription, initiation
EVS87_RS07205	COG1217	gtp-binding protein TYPA
EVS87_RS07215	COG4896	Protein conserved in bacteria
EVS87_RS07225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EVS87_RS07230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EVS87_RS07235	COG2066	Belongs to the glutaminase family
EVS87_RS07240	COG4838	Belongs to the UPF0358 family
EVS87_RS07245	COG0772	Belongs to the SEDS family
EVS87_RS07250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EVS87_RS07255	COG0415	Belongs to the DNA photolyase family
EVS87_RS07260	COG1612	heme a metabolic process
EVS87_RS07265	COG0109	protoheme IX farnesyltransferase activity
EVS87_RS07270	COG2010	Cytochrome c
EVS87_RS07270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVS87_RS07275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVS87_RS07280	COG1845	cytochrome c oxidase, subunit III
EVS87_RS07285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EVS87_RS07290	COG3336	cytochrome c oxidase
EVS87_RS07300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EVS87_RS07305	COG2340	Cysteine-rich secretory protein family
EVS87_RS07325	COG3679	Belongs to the UPF0342 family
EVS87_RS07330	COG4471	UPF0298 protein
EVS87_RS07335	COG0742	ribosomal rna small subunit methyltransferase
EVS87_RS07340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EVS87_RS07345	COG3314	Sporulation integral membrane protein YlbJ
EVS87_RS07350	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVS87_RS07355	COG3480	Lon protease (S16) C-terminal proteolytic domain
EVS87_RS07365	COG1399	metal-binding, possibly nucleic acid-binding protein
EVS87_RS07370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EVS87_RS07380	COG0454	-acetyltransferase
EVS87_RS07385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EVS87_RS07390	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EVS87_RS07395	COG2001	Belongs to the MraZ family
EVS87_RS07400	COG0275	rRNA processing
EVS87_RS07405	COG4839	cell division protein FtsL
EVS87_RS07410	COG0768	penicillin binding
EVS87_RS07420	COG0768	penicillin binding
EVS87_RS07425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EVS87_RS07430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS87_RS07435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVS87_RS07440	COG0772	Belongs to the SEDS family
EVS87_RS07445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVS87_RS07450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EVS87_RS07455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EVS87_RS07460	COG3879	Bacterial protein of unknown function (DUF881)
EVS87_RS07465	COG3879	Bacterial protein of unknown function (DUF881)
EVS87_RS07470	COG3856	small basic protein
EVS87_RS07475	COG0849	cell division
EVS87_RS07480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EVS87_RS07485	COG4412	M6 family metalloprotease domain protein
EVS87_RS07485	COG1404	Belongs to the peptidase S8 family
EVS87_RS07495	COG1191	sigma factor activity
EVS87_RS07500	COG1191	sigma factor activity
EVS87_RS07505	COG2390	Transcriptional regulator
EVS87_RS07520	COG3730	PTS system glucitol sorbitol-specific
EVS87_RS07525	COG3732	PTS system glucitol sorbitol-specific
EVS87_RS07535	COG1119	ATPase activity
EVS87_RS07540	COG1873	PFAM PRC-barrel domain
EVS87_RS07545	COG1496	oxidoreductase activity
EVS87_RS07550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EVS87_RS07555	COG1799	cell septum assembly
EVS87_RS07560	COG0762	integral membrane protein
EVS87_RS07565	COG2302	S4 RNA-binding domain
EVS87_RS07570	COG3599	regulation of cell shape
EVS87_RS07575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EVS87_RS07580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_RS07585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVS87_RS07590	COG0564	pseudouridine synthase activity
EVS87_RS07595	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EVS87_RS07600	COG2233	PERMEase
EVS87_RS07605	COG0540	Belongs to the ATCase OTCase family
EVS87_RS07610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EVS87_RS07615	COG0505	Belongs to the CarA family
EVS87_RS07620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVS87_RS07625	COG0543	2 iron, 2 sulfur cluster binding
EVS87_RS07630	COG0167	dihydroorotate dehydrogenase activity
EVS87_RS07635	COG0284	orotidine-5'-phosphate decarboxylase activity
EVS87_RS07640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVS87_RS07650	COG0175	sulfate reduction
EVS87_RS07655	COG0306	phosphate transporter
EVS87_RS07660	COG2046	Belongs to the sulfate adenylyltransferase family
EVS87_RS07665	COG0529	Catalyzes the synthesis of activated sulfate
EVS87_RS07670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EVS87_RS07675	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EVS87_RS07680	COG1648	precorrin-2 dehydrogenase activity
EVS87_RS07690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EVS87_RS07695	COG1561	YicC-like family, N-terminal region
EVS87_RS07700	COG2052	Domain of unknown function (DUF370)
EVS87_RS07705	COG0194	GDP metabolic process
EVS87_RS07710	COG1758	RNA polymerase activity
EVS87_RS07715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVS87_RS07720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EVS87_RS07725	COG0242	peptide deformylase activity
EVS87_RS07730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EVS87_RS07735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVS87_RS07735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EVS87_RS07740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EVS87_RS07745	COG0631	protein serine/threonine phosphatase activity
EVS87_RS07750	COG2815	serine threonine protein kinase
EVS87_RS07750	COG0515	serine threonine protein kinase
EVS87_RS07755	COG1162	GTPase activity
EVS87_RS07760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVS87_RS07765	COG1564	THIamine pyrophosphokinase
EVS87_RS07775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EVS87_RS07780	COG1302	Protein conserved in bacteria
EVS87_RS07785	COG1461	Dihydroxyacetone kinase
EVS87_RS07790	COG1760	l-serine dehydratase
EVS87_RS07795	COG1760	l-serine dehydratase
EVS87_RS07800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EVS87_RS07805	COG1349	DNA-binding transcription factor activity
EVS87_RS07810	COG0416	fatty acid biosynthetic process
EVS87_RS07815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EVS87_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS07825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_RS07835	COG1196	nuclear chromosome segregation
EVS87_RS07840	COG0552	protein localization to endoplasmic reticulum
EVS87_RS07845	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EVS87_RS07850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EVS87_RS07855	COG0228	four-way junction DNA binding
EVS87_RS07860	COG1837	Belongs to the UPF0109 family
EVS87_RS07870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EVS87_RS07875	COG0336	Belongs to the RNA methyltransferase TrmD family
EVS87_RS07880	COG0335	large ribosomal subunit rRNA binding
EVS87_RS07885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EVS87_RS07890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVS87_RS07900	COG2257	FlhB HrpN YscU SpaS Family
EVS87_RS07905	COG0045	succinate-CoA ligase (ADP-forming) activity
EVS87_RS07910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EVS87_RS07915	COG0758	DNA mediated transformation
EVS87_RS07920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVS87_RS07925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EVS87_RS07930	COG4974	Belongs to the 'phage' integrase family
EVS87_RS07935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EVS87_RS07940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EVS87_RS07945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EVS87_RS07950	COG1815	bacterial-type flagellum-dependent cell motility
EVS87_RS07955	COG1558	bacterial-type flagellum-dependent cell motility
EVS87_RS07960	COG1677	Flagellar hook-basal body complex protein FliE
EVS87_RS07965	COG1766	The M ring may be actively involved in energy transduction
EVS87_RS07970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_RS07975	COG1317	bacterial-type flagellum organization
EVS87_RS07980	COG1157	protein secretion by the type III secretion system
EVS87_RS07985	COG2882	bacterial-type flagellum organization
EVS87_RS07990	COG3334	PFAM MgtE intracellular
EVS87_RS07995	COG3144	bacterial-type flagellum assembly
EVS87_RS08000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EVS87_RS08005	COG4786	Flagellar basal body rod
EVS87_RS08010	COG1582	Flagellar protein (FlbD)
EVS87_RS08015	COG1580	Controls the rotational direction of flagella during chemotaxis
EVS87_RS08020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_RS08025	COG1776	CheC inhibitor of MCP methylation
EVS87_RS08025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_RS08030	COG2201	protein-glutamate methylesterase activity
EVS87_RS08035	COG3190	flagellar
EVS87_RS08040	COG1338	Plays a role in the flagellum-specific transport system
EVS87_RS08045	COG1987	bacterial-type flagellum assembly
EVS87_RS08050	COG1684	flagellar biosynthetic protein fliR
EVS87_RS08055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EVS87_RS08060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EVS87_RS08065	COG1419	protein localization to endoplasmic reticulum
EVS87_RS08070	COG0455	bacterial-type flagellum organization
EVS87_RS08075	COG2201	protein-glutamate methylesterase activity
EVS87_RS08080	COG0643	Histidine kinase
EVS87_RS08080	COG2198	Histidine kinase
EVS87_RS08085	COG0835	chemotaxis
EVS87_RS08090	COG1776	CheC inhibitor of MCP methylation
EVS87_RS08100	COG1191	sigma factor activity
EVS87_RS08115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EVS87_RS08120	COG0528	UMP kinase activity
EVS87_RS08125	COG0233	cytoplasmic translational termination
EVS87_RS08130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVS87_RS08135	COG4589	Belongs to the CDS family
EVS87_RS08140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EVS87_RS08145	COG0750	zinc metalloprotease
EVS87_RS08150	COG0442	prolyl-tRNA aminoacylation
EVS87_RS08155	COG2176	DNA-directed DNA polymerase activity
EVS87_RS08170	COG3693	PFAM glycoside hydrolase, family 10
EVS87_RS08185	COG0779	Required for maturation of 30S ribosomal subunits
EVS87_RS08190	COG0195	Participates in both transcription termination and antitermination
EVS87_RS08195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EVS87_RS08200	COG1358	cellular component organization or biogenesis
EVS87_RS08205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EVS87_RS08210	COG1550	Protein conserved in bacteria
EVS87_RS08215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EVS87_RS08220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EVS87_RS08225	COG0196	riboflavin kinase activity
EVS87_RS08230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EVS87_RS08235	COG1185	polyribonucleotide nucleotidyltransferase activity
EVS87_RS08240	COG0726	polysaccharide deacetylase
EVS87_RS08245	COG0612	Peptidase, M16
EVS87_RS08250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_RS08260	COG1132	(ABC) transporter
EVS87_RS08265	COG1132	(ABC) transporter
EVS87_RS08300	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
EVS87_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS08330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_RS08335	COG1260	myo-inositol-1-phosphate synthase
EVS87_RS08380	COG0367	asparagine synthase
EVS87_RS08385	COG1873	PFAM PRC-barrel domain
EVS87_RS08390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_RS08395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVS87_RS08400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EVS87_RS08405	COG0527	aspartate kinase activity
EVS87_RS08415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVS87_RS08420	COG0740	serine-type endopeptidase activity
EVS87_RS08430	COG4980	gas vesicle protein
EVS87_RS08430	COG1674	ftsk spoiiie
EVS87_RS08435	COG2188	Transcriptional regulator
EVS87_RS08440	COG2814	Major facilitator Superfamily
EVS87_RS08445	COG1033	growth of symbiont in host cell
EVS87_RS08445	COG2409	Drug exporters of the RND superfamily
EVS87_RS08450	COG0612	Peptidase, M16
EVS87_RS08455	COG0612	Peptidase, M16
EVS87_RS08465	COG2409	Drug exporters of the RND superfamily
EVS87_RS08465	COG1033	growth of symbiont in host cell
EVS87_RS08470	COG0300	oxidoreductase activity
EVS87_RS08485	COG1426	Protein conserved in bacteria
EVS87_RS08490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EVS87_RS08495	COG1058	Belongs to the CinA family
EVS87_RS08495	COG1546	Belongs to the CinA family
EVS87_RS08500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EVS87_RS08505	COG1418	mRNA catabolic process
EVS87_RS08510	COG1692	metallophosphoesterase
EVS87_RS08515	COG2359	stage V sporulation protein S
EVS87_RS08520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS87_RS08525	COG1063	alcohol dehydrogenase
EVS87_RS08530	COG0156	8-amino-7-oxononanoate synthase activity
EVS87_RS08535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVS87_RS08540	COG4550	Control of competence regulator ComK, YlbF/YmcA
EVS87_RS08550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EVS87_RS08555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EVS87_RS08575	COG1329	Transcriptional regulator
EVS87_RS08580	COG4195	phage-related replication protein
EVS87_RS08585	COG0457	Tetratricopeptide repeat
EVS87_RS08590	COG1404	Belongs to the peptidase S8 family
EVS87_RS08595	COG4195	phage-related replication protein
EVS87_RS08600	COG1764	response to oxidative stress
EVS87_RS08605	COG2076	Multidrug Resistance protein
EVS87_RS08630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EVS87_RS08635	COG1923	regulation of RNA biosynthetic process
EVS87_RS08650	COG1780	Probably involved in ribonucleotide reductase function
EVS87_RS08655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS87_RS08660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS87_RS08665	COG4112	unkown
EVS87_RS08675	COG0464	growth
EVS87_RS08680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EVS87_RS08685	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EVS87_RS08690	COG0789	Transcriptional regulator
EVS87_RS08695	COG0174	glutamine synthetase
EVS87_RS08715	COG0457	Tetratricopeptide repeat
EVS87_RS08735	COG5444	nuclease activity
EVS87_RS08760	COG5646	InterPro IPR014922
EVS87_RS08780	COG0457	Tetratricopeptide repeat
EVS87_RS08790	COG3619	membrane
EVS87_RS08795	COG1793	dna ligase
EVS87_RS08795	COG3285	dna ligase
EVS87_RS08800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EVS87_RS08805	COG4876	unkown
EVS87_RS08815	COG1959	2 iron, 2 sulfur cluster binding
EVS87_RS08820	COG0702	epimerase
EVS87_RS08825	COG0247	lactate metabolic process
EVS87_RS08830	COG1139	Iron-sulfur cluster binding protein
EVS87_RS08835	COG1556	Lactate utilization protein
EVS87_RS08855	COG2323	membrane
EVS87_RS08860	COG1309	transcriptional regulator
EVS87_RS08865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVS87_RS08865	COG2124	cytochrome p450
EVS87_RS08870	COG3591	Belongs to the peptidase S1B family
EVS87_RS08875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EVS87_RS08880	COG3209	COG3209 Rhs family protein
EVS87_RS08885	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS08900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVS87_RS08905	COG1388	LysM domain
EVS87_RS08910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EVS87_RS08915	COG4224	UPF0291 protein
EVS87_RS08920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EVS87_RS08930	COG3763	UPF0154 protein
EVS87_RS08940	COG0785	Cytochrome C biogenesis protein
EVS87_RS08945	COG4846	Membrane protein involved in cytochrome C biogenesis
EVS87_RS08955	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_RS08970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EVS87_RS08975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS08995	COG0824	Thioesterase
EVS87_RS09005	COG4841	protein insertion into membrane
EVS87_RS09010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EVS87_RS09015	COG1832	CoA-binding protein
EVS87_RS09020	COG0187	DNA topoisomerase II activity
EVS87_RS09025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS87_RS09035	COG0738	Major facilitator superfamily
EVS87_RS09040	COG0473	3-isopropylmalate dehydrogenase activity
EVS87_RS09045	COG0110	maltose O-acetyltransferase activity
EVS87_RS09055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EVS87_RS09060	COG0640	Transcriptional regulator
EVS87_RS09070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EVS87_RS09075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_RS09085	COG1309	transcriptional regulator
EVS87_RS09090	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_RS09095	COG1733	regulation of RNA biosynthetic process
EVS87_RS09100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_RS09105	COG0251	oxidation-reduction process
EVS87_RS09145	COG0657	acetylesterase activity
EVS87_RS09150	COG0789	Transcriptional regulator
EVS87_RS09155	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS09160	COG2190	(PTS) system
EVS87_RS09160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS09160	COG1263	PTS System
EVS87_RS09175	COG2205	protein histidine kinase activity
EVS87_RS09180	COG0745	RESPONSE REGULATOR receiver
EVS87_RS09190	COG3507	Belongs to the glycosyl hydrolase 43 family
EVS87_RS09195	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS09200	COG1486	melibiose metabolic process
EVS87_RS09205	COG0395	ABC-type sugar transport system, permease component
EVS87_RS09210	COG1175	transmembrane transport
EVS87_RS09215	COG1653	transport
EVS87_RS09220	COG1609	Transcriptional regulator
EVS87_RS09225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVS87_RS09240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS09270	COG5444	nuclease activity
EVS87_RS09275	COG1846	Transcriptional regulator
EVS87_RS09280	COG2814	Major facilitator Superfamily
EVS87_RS09290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS09290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS09290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS09295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS09295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_RS09295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS09300	COG1105	Belongs to the carbohydrate kinase PfkB family
EVS87_RS09310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_RS09335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVS87_RS09340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_RS09350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_RS09355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVS87_RS09360	COG1024	Enoyl-CoA hydratase
EVS87_RS09365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS87_RS09370	COG0511	ligase activity, forming carbon-carbon bonds
EVS87_RS09375	COG0439	Biotin carboxylase
EVS87_RS09380	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS09385	COG1960	acyl-CoA dehydrogenase activity
EVS87_RS09390	COG1649	PFAM Uncharacterised BCR, COG1649
EVS87_RS09395	COG2365	Tyrosine phosphatase family
EVS87_RS09400	COG1349	DNA-binding transcription factor activity
EVS87_RS09405	COG1942	4-Oxalocrotonate Tautomerase
EVS87_RS09415	COG3835	regulator
EVS87_RS09420	COG0277	FAD linked oxidase domain protein
EVS87_RS09425	COG0247	lactate metabolic process
EVS87_RS09445	COG0166	Belongs to the GPI family
EVS87_RS09450	COG2246	polysaccharide biosynthetic process
EVS87_RS09455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVS87_RS09460	COG0586	Pfam SNARE associated Golgi protein
EVS87_RS09465	COG1587	Uroporphyrinogen-III synthase
EVS87_RS09475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS09490	COG0534	Mate efflux family protein
EVS87_RS09495	COG2027	D-alanyl-D-alanine carboxypeptidase
EVS87_RS09500	COG4677	pectinesterase activity
EVS87_RS09505	COG2323	membrane
EVS87_RS09510	COG2146	nitrite reductase [NAD(P)H] activity
EVS87_RS09515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_RS09520	COG0243	molybdopterin cofactor binding
EVS87_RS09525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_RS09530	COG2223	nitrite transmembrane transporter activity
EVS87_RS09535	COG0493	'glutamate synthase
EVS87_RS09540	COG0067	glutamate synthase
EVS87_RS09540	COG0070	glutamate synthase
EVS87_RS09540	COG0069	glutamate synthase activity
EVS87_RS09545	COG0583	DNA-binding transcription factor activity
EVS87_RS09555	COG1132	(ABC) transporter
EVS87_RS09560	COG4978	Transcriptional regulator
EVS87_RS09560	COG0789	Transcriptional regulator
EVS87_RS09565	COG0454	-acetyltransferase
EVS87_RS09570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVS87_RS09575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVS87_RS09580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_RS09590	COG0243	molybdopterin cofactor binding
EVS87_RS09600	COG1070	Carbohydrate kinase
EVS87_RS09605	COG2115	Belongs to the xylose isomerase family
EVS87_RS09610	COG1940	carbohydrate kinase activity
EVS87_RS09620	COG2211	Major facilitator Superfamily
EVS87_RS09625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_RS09630	COG1994	Peptidase M50
EVS87_RS09650	COG1309	transcriptional regulator
EVS87_RS09655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS09660	COG3708	Transcriptional regulator
EVS87_RS09665	COG2378	regulation of single-species biofilm formation
EVS87_RS09675	COG0640	Transcriptional regulator
EVS87_RS09680	COG0531	amino acid
EVS87_RS09685	COG0741	lytic transglycosylase activity
EVS87_RS09690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EVS87_RS09695	COG2079	MmgE PrpD family protein
EVS87_RS09700	COG0372	Belongs to the citrate synthase family
EVS87_RS09705	COG2322	membrane
EVS87_RS09715	COG3584	3D domain protein
EVS87_RS09715	COG1388	LysM domain
EVS87_RS09720	COG0514	ATP-dependent DNA helicase (RecQ)
EVS87_RS09730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS09765	COG1657	PFAM Prenyltransferase squalene oxidase
EVS87_RS09770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EVS87_RS09775	COG0385	Bile acid
EVS87_RS09780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS09785	COG0567	Dehydrogenase, E1 component
EVS87_RS09790	COG4548	von Willebrand factor, type A
EVS87_RS09795	COG0714	Associated with various cellular activities
EVS87_RS09800	COG2032	superoxide dismutase activity
EVS87_RS09805	COG0791	NLP P60 protein
EVS87_RS09805	COG1388	LysM domain
EVS87_RS09810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EVS87_RS09815	COG0534	Mate efflux family protein
EVS87_RS09820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_RS09825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_RS09835	COG2962	Rard protein
EVS87_RS09850	COG1733	regulation of RNA biosynthetic process
EVS87_RS09855	COG0778	Nitroreductase
EVS87_RS09865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_RS09870	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS09870	COG0793	Belongs to the peptidase S41A family
EVS87_RS09875	COG2226	methyltransferase
EVS87_RS09885	COG1876	peptidase activity
EVS87_RS09890	COG0813	purine-nucleoside phosphorylase activity
EVS87_RS09900	COG0671	phosphoesterase, PA-phosphatase related
EVS87_RS09915	COG4479	Belongs to the UPF0346 family
EVS87_RS09925	COG1509	lysine 2,3-aminomutase activity
EVS87_RS09930	COG3829	transcription factor binding
EVS87_RS09935	COG0463	Glycosyl transferase, family 2
EVS87_RS09950	COG4641	Protein conserved in bacteria
EVS87_RS09960	COG1086	Polysaccharide biosynthesis protein
EVS87_RS09965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS87_RS09970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS87_RS09975	COG1846	Transcriptional regulator
EVS87_RS09995	COG4698	Protein conserved in bacteria
EVS87_RS10000	COG2755	lipolytic protein G-D-S-L family
EVS87_RS10005	COG1999	signal sequence binding
EVS87_RS10020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EVS87_RS10025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EVS87_RS10030	COG1272	protein, Hemolysin III
EVS87_RS10035	COG0204	Acyl-transferase
EVS87_RS10040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EVS87_RS10045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EVS87_RS10050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EVS87_RS10060	COG2136	Putative SAM-dependent methyltransferase
EVS87_RS10060	COG2521	methyltransferase
EVS87_RS10070	COG0129	dihydroxy-acid dehydratase activity
EVS87_RS10075	COG1413	lyase activity
EVS87_RS10080	COG1418	mRNA catabolic process
EVS87_RS10085	COG0386	Belongs to the glutathione peroxidase family
EVS87_RS10090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EVS87_RS10095	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EVS87_RS10100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVS87_RS10110	COG1278	Cold shock
EVS87_RS10125	COG0328	RNA-DNA hybrid ribonuclease activity
EVS87_RS10130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EVS87_RS10135	COG0328	RNA-DNA hybrid ribonuclease activity
EVS87_RS10145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_RS10155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EVS87_RS10165	COG1755	Isoprenylcysteine carboxyl methyltransferase
EVS87_RS10170	COG3424	synthase
EVS87_RS10175	COG0726	polysaccharide deacetylase
EVS87_RS10180	COG2233	PERMEase
EVS87_RS10185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_RS10190	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EVS87_RS10195	COG1199	ATP-dependent helicase activity
EVS87_RS10205	COG0116	Belongs to the methyltransferase superfamily
EVS87_RS10215	COG3599	regulation of cell shape
EVS87_RS10220	COG4474	Belongs to the UPF0398 family
EVS87_RS10230	COG3359	exonuclease
EVS87_RS10235	COG1205	dead DEAH box helicase
EVS87_RS10235	COG1111	helicase
EVS87_RS10240	COG1902	pentaerythritol trinitrate reductase activity
EVS87_RS10245	COG2190	(PTS) system
EVS87_RS10250	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_RS10280	COG3331	DNA recombination
EVS87_RS10285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_RS10285	COG4499	WXG100 protein secretion system (Wss), protein YukC
EVS87_RS10295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EVS87_RS10300	COG3935	DnaD domain protein
EVS87_RS10305	COG0017	Asparaginyl-tRNA synthetase
EVS87_RS10310	COG5353	protein conserved in bacteria
EVS87_RS10320	COG1199	ATP-dependent helicase activity
EVS87_RS10320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EVS87_RS10325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EVS87_RS10330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EVS87_RS10335	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EVS87_RS10345	COG0617	tRNA 3'-terminal CCA addition
EVS87_RS10350	COG0438	transferase activity, transferring glycosyl groups
EVS87_RS10355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_RS10360	COG1803	Methylglyoxal synthase
EVS87_RS10365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EVS87_RS10370	COG1694	Mazg nucleotide pyrophosphohydrolase
EVS87_RS10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_RS10385	COG4347	Protein of unknown function (DUF1405)
EVS87_RS10390	COG2010	Cytochrome c
EVS87_RS10390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVS87_RS10395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVS87_RS10400	COG0723	plastoquinol--plastocyanin reductase activity
EVS87_RS10410	COG5582	Belongs to the UPF0302 family
EVS87_RS10415	COG0457	Tetratricopeptide repeat
EVS87_RS10420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EVS87_RS10425	COG0287	Prephenate dehydrogenase
EVS87_RS10430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVS87_RS10435	COG0159	tryptophan synthase activity
EVS87_RS10440	COG0133	tryptophan synthase activity
EVS87_RS10445	COG0135	phosphoribosylanthranilate isomerase activity
EVS87_RS10450	COG0134	indole-3-glycerol-phosphate synthase activity
EVS87_RS10455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVS87_RS10465	COG4401	Chorismate mutase type I
EVS87_RS10470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EVS87_RS10475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EVS87_RS10480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EVS87_RS10485	COG0105	UTP biosynthetic process
EVS87_RS10490	COG0142	geranyltranstransferase activity
EVS87_RS10495	COG2226	methyltransferase
EVS87_RS10500	COG0142	geranyltranstransferase activity
EVS87_RS10510	COG0302	gtp cyclohydrolase
EVS87_RS10515	COG0776	regulation of translation
EVS87_RS10520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EVS87_RS10535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EVS87_RS10540	COG1160	GTP binding
EVS87_RS10570	COG1304	FMN binding
EVS87_RS10575	COG0539	negative regulation of cytoplasmic translation
EVS87_RS10580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EVS87_RS10590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EVS87_RS10595	COG2959	enzyme of heme biosynthesis
EVS87_RS10600	COG3773	Cell wall hydrolase
EVS87_RS10600	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS10605	COG2339	peptidase activity
EVS87_RS10610	COG0492	ferredoxin-NADP+ reductase activity
EVS87_RS10615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_RS10620	COG4862	establishment of competence for transformation
EVS87_RS10625	COG1408	metallophosphoesterase
EVS87_RS10635	COG1388	LysM domain
EVS87_RS10640	COG1266	CAAX protease self-immunity
EVS87_RS10645	COG0514	ATP-dependent DNA helicase (RecQ)
EVS87_RS10650	COG4955	Helix-turn-helix domain
EVS87_RS10655	COG1141	Ferredoxin
EVS87_RS10660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EVS87_RS10665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVS87_RS10680	COG1595	DNA-templated transcription, initiation
EVS87_RS10685	COG5002	protein histidine kinase activity
EVS87_RS10690	COG0745	RESPONSE REGULATOR receiver
EVS87_RS10695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVS87_RS10700	COG1333	cytochrome c biogenesis protein
EVS87_RS10705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS10710	COG1187	pseudouridine synthase activity
EVS87_RS10715	COG0700	Nucleoside recognition
EVS87_RS10720	COG2715	membrane protein required for spore maturation
EVS87_RS10725	COG1686	Belongs to the peptidase S11 family
EVS87_RS10735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EVS87_RS10740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EVS87_RS10750	COG1547	Domain of unknown function (DUF309)
EVS87_RS10755	COG0456	acetyltransferase
EVS87_RS10760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EVS87_RS10765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS10765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS10770	COG0307	riboflavin synthase, alpha
EVS87_RS10795	COG2814	Major facilitator Superfamily
EVS87_RS10800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVS87_RS10805	COG4086	secreted protein
EVS87_RS10810	COG0019	diaminopimelate decarboxylase activity
EVS87_RS10815	COG0697	spore germination
EVS87_RS10830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVS87_RS10850	COG1191	sigma factor activity
EVS87_RS10855	COG2172	sigma factor antagonist activity
EVS87_RS10865	COG1686	Belongs to the peptidase S11 family
EVS87_RS10870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EVS87_RS10875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EVS87_RS10880	COG4974	Belongs to the 'phage' integrase family
EVS87_RS10890	COG0735	belongs to the Fur family
EVS87_RS10895	COG1300	Membrane
EVS87_RS10900	COG1404	Belongs to the peptidase S8 family
EVS87_RS10910	COG2153	protein acetylation
EVS87_RS10915	COG1379	DNA repair
EVS87_RS10920	COG0494	nUDIX hydrolase
EVS87_RS10925	COG0667	Aldo Keto reductase
EVS87_RS10940	COG1073	alpha beta
EVS87_RS10945	COG0457	Tetratricopeptide repeat
EVS87_RS10955	COG4918	Iron-sulphur cluster biosynthesis
EVS87_RS10960	COG4305	rare lipoprotein A
EVS87_RS10965	COG0456	acetyltransferase
EVS87_RS10965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EVS87_RS10970	COG0456	acetyltransferase
EVS87_RS10980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVS87_RS10990	COG2211	Major facilitator Superfamily
EVS87_RS10995	COG1072	(Pantothenic acid kinase))
EVS87_RS11000	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVS87_RS11010	COG0300	oxidoreductase activity
EVS87_RS11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS11020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_RS11030	COG4187	Peptidase family M20/M25/M40
EVS87_RS11035	COG1902	pentaerythritol trinitrate reductase activity
EVS87_RS11040	COG0596	Alpha beta hydrolase
EVS87_RS11045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_RS11055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EVS87_RS11060	COG2188	Transcriptional regulator
EVS87_RS11065	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS11070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS11075	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_RS11080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS11105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EVS87_RS11110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVS87_RS11120	COG0706	membrane insertase activity
EVS87_RS11125	COG0835	chemotaxis
EVS87_RS11130	COG2195	Cleaves the N-terminal amino acid of tripeptides
EVS87_RS11135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVS87_RS11140	COG0346	lactoylglutathione lyase activity
EVS87_RS11150	COG1376	ErfK ybiS ycfS ynhG family protein
EVS87_RS11155	COG4129	membrane
EVS87_RS11160	COG1126	abc transporter atp-binding protein
EVS87_RS11165	COG0765	amino acid transport
EVS87_RS11170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS11180	COG1597	lipid kinase activity
EVS87_RS11190	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_RS11195	COG0022	dehydrogenase e1 component
EVS87_RS11200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_RS11205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_RS11210	COG3426	butyrate kinase activity
EVS87_RS11215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_RS11220	COG0280	phosphate acetyltransferase
EVS87_RS11225	COG3290	protein histidine kinase activity
EVS87_RS11225	COG3829	transcription factor binding
EVS87_RS11235	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_RS11240	COG0457	Tetratricopeptide repeat
EVS87_RS11245	COG0745	RESPONSE REGULATOR receiver
EVS87_RS11250	COG0750	zinc metalloprotease
EVS87_RS11255	COG0497	DNA recombination
EVS87_RS11260	COG1438	arginine binding
EVS87_RS11265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EVS87_RS11270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EVS87_RS11275	COG0142	geranyltranstransferase activity
EVS87_RS11280	COG1722	exodeoxyribonuclease VII activity
EVS87_RS11285	COG1570	exodeoxyribonuclease VII activity
EVS87_RS11290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EVS87_RS11295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVS87_RS11300	COG1302	Protein conserved in bacteria
EVS87_RS11305	COG0439	Biotin carboxylase
EVS87_RS11310	COG0511	ligase activity, forming carbon-carbon bonds
EVS87_RS11350	COG3854	ATPases associated with a variety of cellular activities
EVS87_RS11360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EVS87_RS11365	COG0006	proline dipeptidase activity
EVS87_RS11370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EVS87_RS11380	COG3872	metal-dependent enzyme
EVS87_RS11390	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVS87_RS11395	COG1321	iron dependent repressor
EVS87_RS11400	COG0095	Lipoate-protein ligase
EVS87_RS11405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_RS11420	COG0745	RESPONSE REGULATOR receiver
EVS87_RS11425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS87_RS11430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS87_RS11435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EVS87_RS11440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVS87_RS11465	COG0681	Belongs to the peptidase S26 family
EVS87_RS11500	COG4970	Tfp pilus assembly protein FimT
EVS87_RS11505	COG4537	Required for transformation and DNA binding
EVS87_RS11510	COG1459	type II secretion system
EVS87_RS11515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EVS87_RS11520	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS11530	COG1393	Belongs to the ArsC family
EVS87_RS11540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS11550	COG0011	TIGRFAM Protein of
EVS87_RS11555	COG2814	Major facilitator Superfamily
EVS87_RS11565	COG2866	Carboxypeptidase
EVS87_RS11570	COG1368	sulfuric ester hydrolase activity
EVS87_RS11575	COG1940	carbohydrate kinase activity
EVS87_RS11580	COG4483	Protein conserved in bacteria
EVS87_RS11585	COG0705	Rhomboid family
EVS87_RS11585	COG0457	Tetratricopeptide repeat
EVS87_RS11590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EVS87_RS11595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_RS11605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVS87_RS11610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVS87_RS11615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVS87_RS11620	COG0581	inorganic phosphate transmembrane transporter activity
EVS87_RS11625	COG0573	inorganic phosphate transmembrane transporter activity
EVS87_RS11630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVS87_RS11635	COG0768	penicillin binding
EVS87_RS11640	COG0477	Major facilitator Superfamily
EVS87_RS11645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EVS87_RS11650	COG2839	Protein conserved in bacteria
EVS87_RS11655	COG5521	maltodextrose utilization protein MalA
EVS87_RS11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_RS11665	COG1388	LysM domain
EVS87_RS11670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EVS87_RS11675	COG4709	membrane
EVS87_RS11680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EVS87_RS11685	COG1940	carbohydrate kinase activity
EVS87_RS11690	COG0735	belongs to the Fur family
EVS87_RS11695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS87_RS11700	COG1121	(ABC) transporter
EVS87_RS11705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_RS11720	COG0513	Belongs to the DEAD box helicase family
EVS87_RS11730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EVS87_RS11735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EVS87_RS11740	COG2384	SAM-dependent methyltransferase
EVS87_RS11745	COG2010	Cytochrome c
EVS87_RS11750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVS87_RS11755	COG0358	DNA primase activity
EVS87_RS11760	COG1671	Belongs to the UPF0178 family
EVS87_RS11765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EVS87_RS11770	COG0517	IMP dehydrogenase activity
EVS87_RS11775	COG0751	glycine-tRNA ligase activity
EVS87_RS11780	COG0752	glycyl-tRNA synthetase alpha subunit
EVS87_RS11785	COG1381	Involved in DNA repair and RecF pathway recombination
EVS87_RS11795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVS87_RS11800	COG0295	cytidine deaminase activity
EVS87_RS11805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EVS87_RS11810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EVS87_RS11815	COG1480	7TM receptor with intracellular HD hydrolase
EVS87_RS11820	COG1702	phosphate starvation-inducible protein PhoH
EVS87_RS11825	COG0561	phosphatase activity
EVS87_RS11845	COG4864	UPF0365 protein
EVS87_RS11850	COG1030	water channel activity
EVS87_RS11855	COG1610	YqeY-like protein
EVS87_RS11865	COG1283	sodium-dependent phosphate transmembrane transporter activity
EVS87_RS11870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVS87_RS11875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EVS87_RS11880	COG2264	protein methyltransferase activity
EVS87_RS11885	COG0484	heat shock protein binding
EVS87_RS11890	COG0443	Heat shock 70 kDa protein
EVS87_RS11895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EVS87_RS11900	COG1420	regulation of RNA biosynthetic process
EVS87_RS11905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVS87_RS11910	COG0481	GTPase activity
EVS87_RS11920	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS11925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EVS87_RS11930	COG0268	Binds directly to 16S ribosomal RNA
EVS87_RS11935	COG1466	dna polymerase III delta subunit
EVS87_RS11945	COG0658	competence protein
EVS87_RS11945	COG2333	competence protein COMEC
EVS87_RS11950	COG2131	deaminase
EVS87_RS11955	COG1555	photosystem II stabilization
EVS87_RS11955	COG1596	polysaccharide export
EVS87_RS11960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_RS11965	COG2226	methyltransferase
EVS87_RS11970	COG0799	negative regulation of ribosome biogenesis
EVS87_RS11975	COG1713	HD superfamily hydrolase involved in NAD metabolism
EVS87_RS11980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EVS87_RS11985	COG1534	Rna-binding protein
EVS87_RS11990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVS87_RS11995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EVS87_RS12000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EVS87_RS12010	COG2755	lipolytic protein G-D-S-L family
EVS87_RS12020	COG0457	Tetratricopeptide repeat
EVS87_RS12030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EVS87_RS12080	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS12080	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS12115	COG3778	Protein conserved in bacteria
EVS87_RS12120	COG3299	homolog of phage Mu protein gp47
EVS87_RS12125	COG3628	GPW Gp25 family protein
EVS87_RS12135	COG4193	domain, Protein
EVS87_RS12140	COG1652	LysM domain
EVS87_RS12145	COG5280	Phage tail tape measure protein TP901
EVS87_RS12145	COG3953	SLT domain
EVS87_RS12145	COG3953	SLT domain
EVS87_RS12145	COG5280	Phage tail tape measure protein TP901
EVS87_RS12200	COG4653	Phage capsid family
EVS87_RS12205	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EVS87_RS12225	COG2369	cell adhesion
EVS87_RS12230	COG5518	Phage portal protein
EVS87_RS12235	COG1783	phage Terminase large subunit
EVS87_RS12240	COG5484	DNA packaging
EVS87_RS12315	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_RS12325	COG1484	DNA-dependent DNA replication
EVS87_RS12375	COG1396	sequence-specific DNA binding
EVS87_RS12380	COG2856	Zn peptidase
EVS87_RS12400	COG2186	Transcriptional regulator
EVS87_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS12420	COG3958	Transketolase
EVS87_RS12425	COG3959	Transketolase, thiamine diphosphate binding domain
EVS87_RS12450	COG0726	polysaccharide deacetylase
EVS87_RS12485	COG1131	(ABC) transporter
EVS87_RS12510	COG2160	L-arabinose isomerase activity
EVS87_RS12525	COG1609	Transcriptional regulator
EVS87_RS12535	COG1846	Transcriptional regulator
EVS87_RS12545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EVS87_RS12550	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EVS87_RS12555	COG1733	regulation of RNA biosynthetic process
EVS87_RS12560	COG0657	acetylesterase activity
EVS87_RS12575	COG3209	COG3209 Rhs family protein
EVS87_RS12580	COG2602	Beta-lactamase
EVS87_RS12585	COG1960	acyl-CoA dehydrogenase activity
EVS87_RS12590	COG1126	abc transporter atp-binding protein
EVS87_RS12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS12600	COG0765	amino acid transport
EVS87_RS12610	COG1063	alcohol dehydrogenase
EVS87_RS12620	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS12625	COG1063	alcohol dehydrogenase
EVS87_RS12630	COG2226	methyltransferase
EVS87_RS12655	COG0626	cystathionine gamma-synthase activity
EVS87_RS12660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_RS12665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EVS87_RS12670	COG2226	methyltransferase
EVS87_RS12685	COG0768	penicillin binding
EVS87_RS12690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EVS87_RS12695	COG0572	uridine kinase
EVS87_RS12700	COG0826	peptidase U32
EVS87_RS12705	COG0826	peptidase U32
EVS87_RS12710	COG4122	O-methyltransferase activity
EVS87_RS12715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVS87_RS12720	COG0183	Belongs to the thiolase family
EVS87_RS12725	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS12730	COG1268	BioY protein
EVS87_RS12735	COG3906	Belongs to the UPF0473 family
EVS87_RS12740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EVS87_RS12745	COG4472	Bacterial protein of unknown function (DUF965)
EVS87_RS12750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EVS87_RS12755	COG0628	permease
EVS87_RS12760	COG1126	abc transporter atp-binding protein
EVS87_RS12765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS12770	COG0765	amino acid transport
EVS87_RS12775	COG0765	amino acid transport
EVS87_RS12790	COG3881	PFAM PRC-barrel domain
EVS87_RS12795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS87_RS12800	COG0457	Tetratricopeptide repeat
EVS87_RS12805	COG0482	sulfurtransferase activity
EVS87_RS12810	COG1104	cysteine desulfurase activity
EVS87_RS12815	COG1959	2 iron, 2 sulfur cluster binding
EVS87_RS12820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EVS87_RS12825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EVS87_RS12840	COG0124	histidyl-tRNA synthetase
EVS87_RS12845	COG3103	Sh3 type 3 domain protein
EVS87_RS12845	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS12845	COG4991	sh3 domain protein
EVS87_RS12850	COG1490	D-aminoacyl-tRNA deacylase activity
EVS87_RS12855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVS87_RS12860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_RS12865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EVS87_RS12865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EVS87_RS12870	COG5416	Lipopolysaccharide assembly protein A domain
EVS87_RS12875	COG0490	domain, Protein
EVS87_RS12880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS87_RS12880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS87_RS12890	COG2244	polysaccharide biosynthetic process
EVS87_RS12895	COG2323	membrane
EVS87_RS12905	COG1862	Preprotein translocase
EVS87_RS12910	COG0343	queuine tRNA-ribosyltransferase activity
EVS87_RS12915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EVS87_RS12925	COG2255	four-way junction helicase activity
EVS87_RS12930	COG0632	four-way junction helicase activity
EVS87_RS12940	COG2112	serine threonine protein kinase
EVS87_RS12950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EVS87_RS12965	COG1388	LysM domain
EVS87_RS12970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EVS87_RS12975	COG0157	Belongs to the NadC ModD family
EVS87_RS12980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EVS87_RS12985	COG1104	cysteine desulfurase activity
EVS87_RS12990	COG1827	regulation of RNA biosynthetic process
EVS87_RS12995	COG0077	Prephenate dehydratase
EVS87_RS13000	COG4492	Belongs to the UPF0735 family
EVS87_RS13005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EVS87_RS13010	COG3290	protein histidine kinase activity
EVS87_RS13015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EVS87_RS13020	COG2868	ribosomal protein
EVS87_RS13025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EVS87_RS13030	COG1994	Peptidase M50
EVS87_RS13035	COG0739	heme binding
EVS87_RS13040	COG2894	cell division
EVS87_RS13045	COG0850	regulation of cytokinetic process
EVS87_RS13050	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EVS87_RS13060	COG1077	Cell shape determining protein MreB Mrl
EVS87_RS13065	COG2003	Belongs to the UPF0758 family
EVS87_RS13070	COG0424	maF-like protein
EVS87_RS13080	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EVS87_RS13085	COG0285	dihydrofolate synthase activity
EVS87_RS13090	COG0525	valine-tRNA ligase activity
EVS87_RS13100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_RS13105	COG1388	LysM domain
EVS87_RS13110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS87_RS13115	COG0113	porphobilinogen synthase activity
EVS87_RS13120	COG1587	Uroporphyrinogen-III synthase
EVS87_RS13125	COG0181	hydroxymethylbilane synthase activity
EVS87_RS13130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVS87_RS13135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVS87_RS13145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EVS87_RS13150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EVS87_RS13155	COG1067	ATP-dependent peptidase activity
EVS87_RS13155	COG0470	DNA polymerase III
EVS87_RS13160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EVS87_RS13165	COG0544	peptidyl-prolyl cis-trans isomerase activity
EVS87_RS13170	COG0457	Tetratricopeptide repeat
EVS87_RS13170	COG1477	protein flavinylation
EVS87_RS13175	COG0066	3-isopropylmalate dehydratase activity
EVS87_RS13180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EVS87_RS13185	COG0473	3-isopropylmalate dehydrogenase activity
EVS87_RS13190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS87_RS13195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVS87_RS13200	COG0440	acetolactate synthase activity
EVS87_RS13205	COG0028	Belongs to the TPP enzyme family
EVS87_RS13210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_RS13215	COG2706	6-phosphogluconolactonase activity
EVS87_RS13220	COG3339	Conserved Protein
EVS87_RS13225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EVS87_RS13230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_RS13235	COG1696	Membrane protein involved in D-alanine export
EVS87_RS13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_RS13310	COG0622	Phosphoesterase
EVS87_RS13315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EVS87_RS13320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EVS87_RS13325	COG5401	PFAM Sporulation and spore germination
EVS87_RS13330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EVS87_RS13335	COG1846	Transcriptional regulator
EVS87_RS13340	COG2197	response regulator
EVS87_RS13345	COG2851	Citrate transporter
EVS87_RS13350	COG0583	DNA-binding transcription factor activity
EVS87_RS13355	COG2828	Protein conserved in bacteria
EVS87_RS13365	COG0824	Thioesterase
EVS87_RS13370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EVS87_RS13375	COG1053	succinate dehydrogenase
EVS87_RS13380	COG2009	succinate dehydrogenase
EVS87_RS13385	COG1719	4-vinyl reductase, 4VR
EVS87_RS13395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS13400	COG0601	transmembrane transport
EVS87_RS13410	COG0527	aspartate kinase activity
EVS87_RS13415	COG0322	excinuclease ABC activity
EVS87_RS13420	COG3118	belongs to the thioredoxin family
EVS87_RS13425	COG3534	alpha-L-arabinofuranosidase
EVS87_RS13430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EVS87_RS13435	COG2086	electron transfer activity
EVS87_RS13440	COG1024	Enoyl-CoA hydratase
EVS87_RS13445	COG1309	transcriptional regulator
EVS87_RS13450	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS13460	COG3766	membrane
EVS87_RS13465	COG1193	negative regulation of DNA recombination
EVS87_RS13470	COG1796	DNA polymerase
EVS87_RS13470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_RS13475	COG1286	toxin biosynthetic process
EVS87_RS13480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EVS87_RS13485	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVS87_RS13490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_RS13490	COG0072	phenylalanine-tRNA ligase activity
EVS87_RS13495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EVS87_RS13500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS87_RS13510	COG1966	Carbon starvation protein
EVS87_RS13515	COG1363	Peptidase, m42
EVS87_RS13525	COG3326	Membrane
EVS87_RS13530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EVS87_RS13535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EVS87_RS13540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EVS87_RS13545	COG1346	cytolysis
EVS87_RS13555	COG3279	Response regulator of the LytR AlgR family
EVS87_RS13560	COG3275	phosphorelay sensor kinase activity
EVS87_RS13565	COG1011	Hydrolase
EVS87_RS13575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVS87_RS13585	COG0398	Pfam SNARE associated Golgi protein
EVS87_RS13590	COG1484	DNA-dependent DNA replication
EVS87_RS13595	COG3611	Membrane attachment protein
EVS87_RS13600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVS87_RS13610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EVS87_RS13615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVS87_RS13620	COG0237	dephospho-CoA kinase activity
EVS87_RS13625	COG1971	Probably functions as a manganese efflux pump
EVS87_RS13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EVS87_RS13635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_RS13635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_RS13640	COG5002	protein histidine kinase activity
EVS87_RS13645	COG0745	RESPONSE REGULATOR receiver
EVS87_RS13650	COG0039	L-malate dehydrogenase activity
EVS87_RS13655	COG0538	isocitrate dehydrogenase activity
EVS87_RS13660	COG0372	Belongs to the citrate synthase family
EVS87_RS13665	COG2707	UPF0756 membrane protein
EVS87_RS13670	COG0628	permease
EVS87_RS13675	COG3030	protein affecting phage T7 exclusion by the F plasmid
EVS87_RS13685	COG0205	6-phosphofructokinase activity
EVS87_RS13690	COG0825	malonyl-CoA metabolic process
EVS87_RS13695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EVS87_RS13700	COG0281	malic enzyme
EVS87_RS13705	COG0587	DNA-directed DNA polymerase activity
EVS87_RS13725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EVS87_RS13740	COG4109	DRTGG domain
EVS87_RS13745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EVS87_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS13760	COG0165	Argininosuccinate lyase
EVS87_RS13765	COG0137	argininosuccinate synthase activity
EVS87_RS13770	COG0521	Mo-molybdopterin cofactor biosynthetic process
EVS87_RS13775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EVS87_RS13780	COG0827	DNA restriction-modification system
EVS87_RS13785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EVS87_RS13790	COG3874	Sporulation protein YtfJ
EVS87_RS13800	COG1714	RDD family
EVS87_RS13805	COG0616	signal peptide processing
EVS87_RS13810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVS87_RS13820	COG3239	Fatty acid desaturase
EVS87_RS13825	COG4585	Histidine kinase
EVS87_RS13830	COG2197	response regulator
EVS87_RS13835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS13840	COG0745	RESPONSE REGULATOR receiver
EVS87_RS13845	COG2205	protein histidine kinase activity
EVS87_RS13850	COG0772	Belongs to the SEDS family
EVS87_RS13855	COG1695	Transcriptional regulator
EVS87_RS13860	COG1136	(ABC) transporter
EVS87_RS13865	COG0577	efflux transmembrane transporter activity
EVS87_RS13870	COG0402	S-adenosylhomocysteine deaminase activity
EVS87_RS13875	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_RS13890	COG1279	arginine transmembrane transporter activity
EVS87_RS13895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_RS13905	COG0301	tRNA thio-modification
EVS87_RS13910	COG1104	cysteine desulfurase activity
EVS87_RS13915	COG1114	Component of the transport system for branched-chain amino acids
EVS87_RS13920	COG1114	Component of the transport system for branched-chain amino acids
EVS87_RS13925	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EVS87_RS13930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_RS13935	COG1309	transcriptional regulator
EVS87_RS13940	COG1956	GAF domain-containing protein
EVS87_RS13945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EVS87_RS13955	COG1335	isochorismatase
EVS87_RS13965	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EVS87_RS13970	COG2329	Antibiotic biosynthesis monooxygenase
EVS87_RS13975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EVS87_RS13980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_RS13985	COG0454	-acetyltransferase
EVS87_RS13990	COG0517	IMP dehydrogenase activity
EVS87_RS13995	COG0123	including yeast histone deacetylase and acetoin utilization protein
EVS87_RS14000	COG1609	Transcriptional regulator
EVS87_RS14005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EVS87_RS14005	COG1605	Chorismate mutase
EVS87_RS14010	COG3118	belongs to the thioredoxin family
EVS87_RS14015	COG4980	gas vesicle protein
EVS87_RS14020	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EVS87_RS14025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVS87_RS14030	COG1674	ftsk spoiiie
EVS87_RS14035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_RS14040	COG4848	Belongs to the UPF0354 family
EVS87_RS14045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS14060	COG1363	Peptidase, m42
EVS87_RS14065	COG5584	Small secreted protein
EVS87_RS14070	COG0281	malic enzyme
EVS87_RS14075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS14080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EVS87_RS14090	COG0510	thiamine kinase activity
EVS87_RS14095	COG1597	lipid kinase activity
EVS87_RS14105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EVS87_RS14110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_RS14115	COG3340	Belongs to the peptidase S51 family
EVS87_RS14120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS87_RS14125	COG2252	PERMEase
EVS87_RS14130	COG1349	DNA-binding transcription factor activity
EVS87_RS14135	COG1187	pseudouridine synthase activity
EVS87_RS14140	COG2244	polysaccharide biosynthetic process
EVS87_RS14145	COG2081	HI0933 family
EVS87_RS14155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EVS87_RS14160	COG3196	Protein conserved in bacteria
EVS87_RS14170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_RS14175	COG5578	integral membrane protein
EVS87_RS14180	COG0673	inositol 2-dehydrogenase activity
EVS87_RS14185	COG1653	transport
EVS87_RS14190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EVS87_RS14195	COG4209	transmembrane transport
EVS87_RS14200	COG2207	Transcriptional regulator
EVS87_RS14205	COG1733	regulation of RNA biosynthetic process
EVS87_RS14210	COG2814	Major facilitator Superfamily
EVS87_RS14215	COG0656	L-ascorbic acid biosynthetic process
EVS87_RS14220	COG1653	transport
EVS87_RS14225	COG0395	ABC-type sugar transport system, permease component
EVS87_RS14230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_RS14235	COG1073	alpha beta
EVS87_RS14240	COG0495	leucyl-tRNA aminoacylation
EVS87_RS14250	COG2202	Pas domain
EVS87_RS14250	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS14255	COG2433	Pfam Transposase IS66
EVS87_RS14260	COG0577	efflux transmembrane transporter activity
EVS87_RS14275	COG1131	(ABC) transporter
EVS87_RS14280	COG1725	Transcriptional regulator
EVS87_RS14300	COG1242	4 iron, 4 sulfur cluster binding
EVS87_RS14305	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EVS87_RS14310	COG4326	sporulation control protein
EVS87_RS14320	COG2267	carboxylic ester hydrolase activity
EVS87_RS14325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EVS87_RS14330	COG0367	asparagine synthase
EVS87_RS14335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EVS87_RS14340	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EVS87_RS14350	COG1506	peptidase
EVS87_RS14355	COG1233	COG1233 Phytoene dehydrogenase and related
EVS87_RS14375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS87_RS14380	COG1116	anion transmembrane transporter activity
EVS87_RS14385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS87_RS14390	COG0494	nUDIX hydrolase
EVS87_RS14395	COG2310	stress, protein
EVS87_RS14410	COG4824	toxin secretion phage lysis holin
EVS87_RS14420	COG0783	Belongs to the Dps family
EVS87_RS14435	COG1854	S-ribosylhomocysteine lyase activity
EVS87_RS14440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EVS87_RS14445	COG0288	reversible hydration of carbon dioxide
EVS87_RS14450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EVS87_RS14450	COG3443	Belongs to the bacterial solute-binding protein 9 family
EVS87_RS14465	COG1271	oxidase subunit
EVS87_RS14470	COG1294	oxidase, subunit
EVS87_RS14485	COG4948	Mandelate Racemase Muconate Lactonizing
EVS87_RS14490	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_RS14495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EVS87_RS14500	COG0596	Alpha beta hydrolase
EVS87_RS14505	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EVS87_RS14510	COG1169	isochorismate synthase
EVS87_RS14515	COG1575	Belongs to the MenA family. Type 1 subfamily
EVS87_RS14520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_RS14650	COG3859	Proton-coupled thiamine transporter YuaJ
EVS87_RS14660	COG1247	-acetyltransferase
EVS87_RS14665	COG3339	Conserved Protein
EVS87_RS14670	COG0772	Belongs to the SEDS family
EVS87_RS14680	COG2268	Band 7 protein
EVS87_RS14685	COG1585	Membrane protein implicated in regulation of membrane protease activity
EVS87_RS14690	COG2318	DinB family
EVS87_RS14695	COG1454	alcohol dehydrogenase
EVS87_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS14705	COG1510	regulation of RNA biosynthetic process
EVS87_RS14720	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS14720	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS14750	COG3778	Protein conserved in bacteria
EVS87_RS14755	COG3299	homolog of phage Mu protein gp47
EVS87_RS14760	COG3628	GPW Gp25 family protein
EVS87_RS14770	COG4193	domain, Protein
EVS87_RS14775	COG1652	LysM domain
EVS87_RS14780	COG3953	SLT domain
EVS87_RS14780	COG5280	Phage tail tape measure protein TP901
EVS87_RS14780	COG3953	SLT domain
EVS87_RS14780	COG5280	Phage tail tape measure protein TP901
EVS87_RS14835	COG4653	Phage capsid family
EVS87_RS14840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EVS87_RS14845	COG5518	Phage portal protein
EVS87_RS14850	COG1783	phage Terminase large subunit
EVS87_RS14855	COG5484	DNA packaging
EVS87_RS14860	COG1595	DNA-templated transcription, initiation
EVS87_RS14870	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_RS14885	COG1396	sequence-specific DNA binding
EVS87_RS14895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EVS87_RS14910	COG0628	permease
EVS87_RS14920	COG0673	inositol 2-dehydrogenase activity
EVS87_RS14925	COG0693	protein deglycase activity
EVS87_RS14930	COG0840	transmembrane signaling receptor activity
EVS87_RS14935	COG0840	transmembrane signaling receptor activity
EVS87_RS14940	COG0840	transmembrane signaling receptor activity
EVS87_RS14945	COG0840	transmembrane signaling receptor activity
EVS87_RS14960	COG2070	2-Nitropropane dioxygenase
EVS87_RS14965	COG0432	Pfam Uncharacterised protein family UPF0047
EVS87_RS14970	COG1253	flavin adenine dinucleotide binding
EVS87_RS14975	COG2738	Putative neutral zinc metallopeptidase
EVS87_RS14985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EVS87_RS15000	COG0166	Belongs to the GPI family
EVS87_RS15005	COG1979	alcohol dehydrogenase
EVS87_RS15010	COG1979	alcohol dehydrogenase
EVS87_RS15015	COG2155	Conserved Protein
EVS87_RS15020	COG1098	S1 RNA binding domain
EVS87_RS15025	COG0436	Aminotransferase
EVS87_RS15030	COG1522	sequence-specific DNA binding
EVS87_RS15035	COG2267	carboxylic ester hydrolase activity
EVS87_RS15045	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EVS87_RS15050	COG2205	protein histidine kinase activity
EVS87_RS15060	COG5018	Exonuclease
EVS87_RS15065	COG2814	Major facilitator Superfamily
EVS87_RS15070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_RS15075	COG3011	Protein conserved in bacteria
EVS87_RS15085	COG3290	protein histidine kinase activity
EVS87_RS15090	COG4565	transcriptional regulatory protein
EVS87_RS15095	COG1744	ABC transporter substrate-binding protein PnrA-like
EVS87_RS15100	COG3845	ABC transporter
EVS87_RS15105	COG4603	Belongs to the binding-protein-dependent transport system permease family
EVS87_RS15110	COG1079	Belongs to the binding-protein-dependent transport system permease family
EVS87_RS15115	COG3493	citrate carrier protein
EVS87_RS15130	COG2111	Na H antiporter
EVS87_RS15130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVS87_RS15135	COG2111	Na H antiporter
EVS87_RS15140	COG1006	Multisubunit Na H antiporter MnhC subunit
EVS87_RS15145	COG0651	ATP synthesis coupled electron transport
EVS87_RS15150	COG1863	multisubunit Na H antiporter MnhE subunit
EVS87_RS15155	COG2212	antiporter activity
EVS87_RS15160	COG1320	monovalent cation:proton antiporter activity
EVS87_RS15165	COG2050	protein possibly involved in aromatic compounds catabolism
EVS87_RS15170	COG2197	response regulator
EVS87_RS15175	COG4585	Histidine kinase
EVS87_RS15185	COG0142	geranyltranstransferase activity
EVS87_RS15200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EVS87_RS15205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EVS87_RS15210	COG1335	isochorismatase
EVS87_RS15215	COG5506	Protein of unknown function (DUF1694)
EVS87_RS15235	COG0628	permease
EVS87_RS15250	COG1418	mRNA catabolic process
EVS87_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS15265	COG1511	domain protein
EVS87_RS15270	COG0433	COG0433 Predicted ATPase
EVS87_RS15270	COG1674	ftsk spoiiie
EVS87_RS15275	COG4499	WXG100 protein secretion system (Wss), protein YukC
EVS87_RS15280	COG5417	Belongs to the EsaB family
EVS87_RS15285	COG4842	Belongs to the WXG100 family
EVS87_RS15290	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EVS87_RS15290	COG2508	Transcriptional regulator
EVS87_RS15295	COG0686	Belongs to the AlaDH PNT family
EVS87_RS15300	COG1268	BioY protein
EVS87_RS15305	COG2056	Na+-H+ antiporter family
EVS87_RS15310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EVS87_RS15315	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EVS87_RS15320	COG3584	3D domain protein
EVS87_RS15330	COG1252	NADH dehydrogenase
EVS87_RS15335	COG0492	ferredoxin-NADP+ reductase activity
EVS87_RS15350	COG0789	Transcriptional regulator
EVS87_RS15355	COG5504	Zn-dependent protease
EVS87_RS15360	COG0316	Belongs to the HesB IscA family
EVS87_RS15365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EVS87_RS15370	COG4844	belongs to the
EVS87_RS15375	COG1252	NADH dehydrogenase
EVS87_RS15385	COG4837	Protein of unknown function (DUF1462)
EVS87_RS15390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EVS87_RS15395	COG0823	Involved in the tonB-independent uptake of proteins
EVS87_RS15395	COG1506	peptidase
EVS87_RS15395	COG4946	Tricorn protease homolog
EVS87_RS15400	COG0083	homoserine kinase activity
EVS87_RS15405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EVS87_RS15410	COG0460	homoserine dehydrogenase
EVS87_RS15415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_RS15420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_RS15425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EVS87_RS15430	COG0647	UMP catabolic process
EVS87_RS15435	COG2445	Protein of unknown function DUF86
EVS87_RS15440	COG4470	Protein conserved in bacteria
EVS87_RS15450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVS87_RS15455	COG0739	heme binding
EVS87_RS15475	COG3377	Domain of unknown function (DUF1805)
EVS87_RS15480	COG0737	Belongs to the 5'-nucleotidase family
EVS87_RS15485	COG1801	Protein of unknown function DUF72
EVS87_RS15490	COG2508	Transcriptional regulator
EVS87_RS15495	COG2140	Oxalate decarboxylase
EVS87_RS15500	COG2814	Major facilitator Superfamily
EVS87_RS15505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EVS87_RS15510	COG2356	endonuclease I
EVS87_RS15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS15525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS15530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS15550	COG5002	protein histidine kinase activity
EVS87_RS15550	COG0642	Histidine kinase
EVS87_RS15555	COG0745	RESPONSE REGULATOR receiver
EVS87_RS15560	COG2311	Membrane
EVS87_RS15570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_RS15575	COG1090	epimerase
EVS87_RS15580	COG1309	transcriptional regulator
EVS87_RS15585	COG0719	Fe-S assembly protein
EVS87_RS15590	COG0822	iron-sulfur transferase activity
EVS87_RS15595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EVS87_RS15600	COG0719	Fe-S assembly protein
EVS87_RS15605	COG0396	ATPase activity
EVS87_RS15610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EVS87_RS15615	COG1464	Belongs to the NlpA lipoprotein family
EVS87_RS15620	COG2011	ABC-type metal ion transport system permease component
EVS87_RS15625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EVS87_RS15635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_RS15640	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EVS87_RS15650	COG0509	glycine decarboxylation via glycine cleavage system
EVS87_RS15655	COG1393	Belongs to the ArsC family
EVS87_RS15660	COG1960	acyl-CoA dehydrogenase activity
EVS87_RS15665	COG0183	Belongs to the thiolase family
EVS87_RS15670	COG1024	Enoyl-CoA hydratase
EVS87_RS15670	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVS87_RS15685	COG5577	PFAM Coat F domain
EVS87_RS15695	COG1120	ATPase activity
EVS87_RS15705	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS15715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_RS15720	COG0745	RESPONSE REGULATOR receiver
EVS87_RS15725	COG2770	Histidine kinase
EVS87_RS15725	COG2205	protein histidine kinase activity
EVS87_RS15730	COG1309	transcriptional regulator
EVS87_RS15735	COG0114	fumarate hydratase activity
EVS87_RS15745	COG0697	spore germination
EVS87_RS15750	COG0814	amino acid
EVS87_RS15765	COG2197	response regulator
EVS87_RS15770	COG4585	Histidine kinase
EVS87_RS15775	COG4758	membrane
EVS87_RS15785	COG1842	Phage shock protein A
EVS87_RS15790	COG4758	membrane
EVS87_RS15795	COG2096	Adenosyltransferase
EVS87_RS15800	COG1120	ATPase activity
EVS87_RS15805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS15810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS15820	COG2721	sulfolactate sulfo-lyase activity
EVS87_RS15825	COG0246	Mannitol dehydrogenase
EVS87_RS15830	COG1609	Transcriptional regulator
EVS87_RS15835	COG1904	glucuronate isomerase
EVS87_RS15840	COG2205	protein histidine kinase activity
EVS87_RS15845	COG0745	RESPONSE REGULATOR receiver
EVS87_RS15850	COG1120	ATPase activity
EVS87_RS15855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS15865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS15870	COG0531	amino acid
EVS87_RS15890	COG1988	membrane-bound metal-dependent
EVS87_RS15895	COG1368	sulfuric ester hydrolase activity
EVS87_RS15900	COG0725	ABC transporter, periplasmic molybdate-binding protein
EVS87_RS15905	COG4149	molybdate abc transporter
EVS87_RS15915	COG0656	L-ascorbic acid biosynthetic process
EVS87_RS15920	COG1940	carbohydrate kinase activity
EVS87_RS15925	COG0025	NhaP-type Na H and K H
EVS87_RS15930	COG2860	membrane
EVS87_RS15935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EVS87_RS15940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVS87_RS15945	COG2217	Heavy metal translocating P-type atpase
EVS87_RS15950	COG1121	(ABC) transporter
EVS87_RS15955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS87_RS15960	COG0803	Belongs to the bacterial solute-binding protein 9 family
EVS87_RS15970	COG3226	Transcriptional regulator
EVS87_RS15975	COG0784	Response regulator, receiver
EVS87_RS15980	COG4191	Histidine kinase
EVS87_RS15985	COG1027	Aspartate ammonia-lyase
EVS87_RS15995	COG2217	Heavy metal translocating P-type atpase
EVS87_RS16000	COG2608	mercury ion transmembrane transporter activity
EVS87_RS16005	COG1937	Protein conserved in bacteria
EVS87_RS16035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EVS87_RS16040	COG0557	exoribonuclease II activity
EVS87_RS16045	COG1647	Serine aminopeptidase, S33
EVS87_RS16050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS87_RS16055	COG2002	toxin-antitoxin pair type II binding
EVS87_RS16060	COG1476	TRANSCRIPTIONal
EVS87_RS16065	COG1396	sequence-specific DNA binding
EVS87_RS16070	COG1396	sequence-specific DNA binding
EVS87_RS16075	COG1733	regulation of RNA biosynthetic process
EVS87_RS16080	COG1174	glycine betaine transport
EVS87_RS16085	COG1732	Glycine betaine
EVS87_RS16090	COG1174	glycine betaine transport
EVS87_RS16095	COG0517	IMP dehydrogenase activity
EVS87_RS16095	COG1125	glycine betaine transport
EVS87_RS16100	COG1510	regulation of RNA biosynthetic process
EVS87_RS16105	COG2095	MarC family integral membrane protein
EVS87_RS16115	COG0456	acetyltransferase
EVS87_RS16135	COG1131	(ABC) transporter
EVS87_RS16145	COG0148	phosphopyruvate hydratase activity
EVS87_RS16150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EVS87_RS16155	COG0149	triose-phosphate isomerase activity
EVS87_RS16160	COG0126	phosphoglycerate kinase activity
EVS87_RS16165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVS87_RS16170	COG2390	Transcriptional regulator
EVS87_RS16175	COG0833	amino acid
EVS87_RS16180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVS87_RS16185	COG3829	transcription factor binding
EVS87_RS16190	COG2186	Transcriptional regulator
EVS87_RS16195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EVS87_RS16205	COG0534	Mate efflux family protein
EVS87_RS16210	COG4608	Belongs to the ABC transporter superfamily
EVS87_RS16215	COG0444	Belongs to the ABC transporter superfamily
EVS87_RS16220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_RS16225	COG0601	transmembrane transport
EVS87_RS16230	COG0747	negative chemotaxis
EVS87_RS16235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_RS16240	COG0110	maltose O-acetyltransferase activity
EVS87_RS16245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVS87_RS16250	COG2244	polysaccharide biosynthetic process
EVS87_RS16255	COG5039	Polysaccharide pyruvyl transferase
EVS87_RS16260	COG1216	Glycosyl transferase, family 2
EVS87_RS16270	COG0438	transferase activity, transferring glycosyl groups
EVS87_RS16275	COG1215	transferase activity, transferring glycosyl groups
EVS87_RS16280	COG0438	transferase activity, transferring glycosyl groups
EVS87_RS16285	COG1086	Polysaccharide biosynthesis protein
EVS87_RS16290	COG0489	protein tyrosine kinase activity
EVS87_RS16295	COG3944	biosynthesis protein
EVS87_RS16300	COG1396	sequence-specific DNA binding
EVS87_RS16310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS16315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS16320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS16325	COG0726	polysaccharide deacetylase
EVS87_RS16330	COG0488	(ABC) transporter
EVS87_RS16335	COG1819	glycosyl
EVS87_RS16360	COG3177	Filamentation induced by cAMP protein fic
EVS87_RS16380	COG0740	serine-type endopeptidase activity
EVS87_RS16385	COG1611	Belongs to the LOG family
EVS87_RS16390	COG1694	Mazg nucleotide pyrophosphohydrolase
EVS87_RS16395	COG0659	secondary active sulfate transmembrane transporter activity
EVS87_RS16400	COG0288	reversible hydration of carbon dioxide
EVS87_RS16405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_RS16415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EVS87_RS16420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS16425	COG1481	regulation of sporulation
EVS87_RS16430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EVS87_RS16435	COG1660	Displays ATPase and GTPase activities
EVS87_RS16440	COG1051	belongs to the nudix hydrolase family
EVS87_RS16445	COG0492	ferredoxin-NADP+ reductase activity
EVS87_RS16450	COG0791	NLP P60 protein
EVS87_RS16450	COG3883	PFAM NLP P60 protein
EVS87_RS16455	COG0457	Tetratricopeptide repeat
EVS87_RS16460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EVS87_RS16460	COG0140	phosphoribosyl-ATP diphosphatase activity
EVS87_RS16465	COG0107	imidazoleglycerol-phosphate synthase activity
EVS87_RS16470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EVS87_RS16475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVS87_RS16480	COG0131	Imidazoleglycerol-phosphate dehydratase
EVS87_RS16485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EVS87_RS16490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EVS87_RS16495	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EVS87_RS16500	COG4990	cell redox homeostasis
EVS87_RS16510	COG2910	NAD(P)H-binding
EVS87_RS16515	COG1959	2 iron, 2 sulfur cluster binding
EVS87_RS16520	COG0110	maltose O-acetyltransferase activity
EVS87_RS16525	COG0546	phosphoglycolate phosphatase activity
EVS87_RS16530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EVS87_RS16535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EVS87_RS16540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EVS87_RS16545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EVS87_RS16550	COG0363	glucosamine-6-phosphate deaminase activity
EVS87_RS16555	COG2188	Transcriptional regulator
EVS87_RS16560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EVS87_RS16565	COG1950	PFAM Membrane protein of
EVS87_RS16570	COG1983	PspC domain protein
EVS87_RS16575	COG3595	metallopeptidase activity
EVS87_RS16595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EVS87_RS16605	COG4897	Protein conserved in bacteria
EVS87_RS16610	COG0574	Belongs to the PEP-utilizing enzyme family
EVS87_RS16610	COG3848	Pyruvate phosphate dikinase
EVS87_RS16615	COG1309	transcriptional regulator
EVS87_RS16620	COG2814	Major facilitator Superfamily
EVS87_RS16630	COG0745	RESPONSE REGULATOR receiver
EVS87_RS16635	COG5002	protein histidine kinase activity
EVS87_RS16640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EVS87_RS16645	COG0463	Glycosyl transferase, family 2
EVS87_RS16650	COG1113	amino acid transport
EVS87_RS16655	COG0778	Nitroreductase
EVS87_RS16660	COG1733	regulation of RNA biosynthetic process
EVS87_RS16665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_RS16675	COG0793	Belongs to the peptidase S41A family
EVS87_RS16675	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_RS16680	COG0730	response to heat
EVS87_RS16685	COG0791	NLP P60 protein
EVS87_RS16685	COG3883	PFAM NLP P60 protein
EVS87_RS16690	COG2177	Part of the ABC transporter FtsEX involved in
EVS87_RS16695	COG2884	Cell division ATP-binding protein ftsE
EVS87_RS16700	COG2010	Cytochrome c
EVS87_RS16705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_RS16725	COG0653	protein targeting
EVS87_RS16730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EVS87_RS16735	COG0840	transmembrane signaling receptor activity
EVS87_RS16750	COG1516	flagellar protein fliS
EVS87_RS16755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EVS87_RS16760	COG1334	flagellar protein FlaG
EVS87_RS16765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EVS87_RS16770	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EVS87_RS16780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_RS16785	COG1256	bacterial-type flagellum assembly
EVS87_RS16785	COG4786	Flagellar basal body rod
EVS87_RS16790	COG3418	PFAM FlgN family protein
EVS87_RS16805	COG1040	competence protein
EVS87_RS16815	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EVS87_RS16820	COG1307	EDD domain protein, DegV family
EVS87_RS16825	COG2197	response regulator
EVS87_RS16830	COG4585	Histidine kinase
EVS87_RS16835	COG1739	Uncharacterized protein family UPF0029
EVS87_RS16840	COG1316	TRANSCRIPTIONal
EVS87_RS16845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS87_RS16850	COG0438	transferase activity, transferring glycosyl groups
EVS87_RS16855	COG1215	transferase activity, transferring glycosyl groups
EVS87_RS16860	COG3206	protein involved in exopolysaccharide biosynthesis
EVS87_RS16865	COG3307	-O-antigen
EVS87_RS16870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_RS16875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVS87_RS16880	COG0297	glycogen (starch) synthase activity
EVS87_RS16880	COG0438	transferase activity, transferring glycosyl groups
EVS87_RS16885	COG2244	polysaccharide biosynthetic process
EVS87_RS16900	COG2247	cell wall binding repeat
EVS87_RS16900	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS16905	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_RS16905	COG2247	cell wall binding repeat
EVS87_RS16910	COG2385	sporulation resulting in formation of a cellular spore
EVS87_RS16910	COG2247	cell wall binding repeat
EVS87_RS16920	COG1316	TRANSCRIPTIONal
EVS87_RS16945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EVS87_RS16950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVS87_RS16955	COG1134	teichoic acid transport
EVS87_RS16960	COG1682	transport, permease protein
EVS87_RS16965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_RS16965	COG1215	transferase activity, transferring glycosyl groups
EVS87_RS16970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_RS16980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EVS87_RS16985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EVS87_RS16990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_RS16995	COG4193	domain, Protein
EVS87_RS17000	COG1482	cell wall glycoprotein biosynthetic process
EVS87_RS17010	COG1175	transmembrane transport
EVS87_RS17015	COG1653	transport
EVS87_RS17020	COG2197	response regulator
EVS87_RS17025	COG2972	Histidine kinase
EVS87_RS17035	COG0454	-acetyltransferase
EVS87_RS17040	COG0800	Aldolase
EVS87_RS17045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS87_RS17050	COG1609	Transcriptional regulator
EVS87_RS17055	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EVS87_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS17065	COG0697	spore germination
EVS87_RS17070	COG0814	amino acid
EVS87_RS17090	COG2814	Major facilitator Superfamily
EVS87_RS17095	COG1316	TRANSCRIPTIONal
EVS87_RS17100	COG0561	phosphatase activity
EVS87_RS17105	COG0791	NLP P60 protein
EVS87_RS17110	COG2843	Capsule synthesis protein
EVS87_RS17120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVS87_RS17125	COG0697	spore germination
EVS87_RS17140	COG1609	Transcriptional regulator
EVS87_RS17145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS87_RS17150	COG1869	D-ribose catabolic process
EVS87_RS17155	COG1129	ABC transporter
EVS87_RS17160	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS87_RS17165	COG1879	ABC-type sugar transport system periplasmic component
EVS87_RS17170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVS87_RS17175	COG0583	DNA-binding transcription factor activity
EVS87_RS17180	COG0028	Belongs to the TPP enzyme family
EVS87_RS17185	COG3527	Alpha-acetolactate decarboxylase
EVS87_RS17190	COG1522	sequence-specific DNA binding
EVS87_RS17195	COG2059	Chromate
EVS87_RS17200	COG2059	Chromate
EVS87_RS17205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVS87_RS17210	COG4715	Zinc finger, swim domain protein
EVS87_RS17215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVS87_RS17220	COG2202	Pas domain
EVS87_RS17220	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_RS17225	COG0561	phosphatase activity
EVS87_RS17240	COG1970	mechanosensitive ion channel activity
EVS87_RS17245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EVS87_RS17250	COG0457	Tetratricopeptide repeat
EVS87_RS17255	COG4786	Flagellar basal body rod
EVS87_RS17260	COG4786	Flagellar basal body rod
EVS87_RS17265	COG1077	Cell shape determining protein MreB Mrl
EVS87_RS17270	COG1609	Transcriptional regulator
EVS87_RS17275	COG1846	Transcriptional regulator
EVS87_RS17280	COG2814	Major facilitator Superfamily
EVS87_RS17285	COG0671	phosphoesterase, PA-phosphatase related
EVS87_RS17290	COG0477	Major facilitator Superfamily
EVS87_RS17295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS17300	COG0765	amino acid transport
EVS87_RS17305	COG1126	abc transporter atp-binding protein
EVS87_RS17310	COG0004	ammonium transporteR
EVS87_RS17315	COG0347	Belongs to the P(II) protein family
EVS87_RS17320	COG0739	heme binding
EVS87_RS17325	COG1247	-acetyltransferase
EVS87_RS17370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_RS17375	COG0523	cobalamin synthesis protein
EVS87_RS17380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVS87_RS17385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EVS87_RS17390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EVS87_RS17395	COG2223	nitrite transmembrane transporter activity
EVS87_RS17405	COG2304	oxidoreductase activity
EVS87_RS17410	COG2304	oxidoreductase activity
EVS87_RS17415	COG2385	sporulation resulting in formation of a cellular spore
EVS87_RS17420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVS87_RS17430	COG4836	Membrane
EVS87_RS17440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EVS87_RS17445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EVS87_RS17450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EVS87_RS17455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EVS87_RS17460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS87_RS17465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EVS87_RS17470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS87_RS17475	COG0356	it plays a direct role in the translocation of protons across the membrane
EVS87_RS17485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EVS87_RS17490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EVS87_RS17495	COG4475	Protein of unknown function (DUF436)
EVS87_RS17500	COG0698	ribose 5-phosphate isomerase
EVS87_RS17505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS87_RS17510	COG1971	Probably functions as a manganese efflux pump
EVS87_RS17515	COG0009	L-threonylcarbamoyladenylate synthase
EVS87_RS17520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EVS87_RS17535	COG2890	protein-(glutamine-N5) methyltransferase activity
EVS87_RS17540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EVS87_RS17550	COG0679	Auxin Efflux Carrier
EVS87_RS17555	COG0281	malic enzyme
EVS87_RS17560	COG1435	thymidine kinase activity
EVS87_RS17565	COG0254	rRNA binding
EVS87_RS17570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EVS87_RS17575	COG1494	fructose-1,6-bisphosphatase
EVS87_RS17580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVS87_RS17585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EVS87_RS17590	COG0191	fructose-bisphosphate aldolase activity
EVS87_RS17595	COG2204	response regulator
EVS87_RS17600	COG4821	SIS domain
EVS87_RS17605	COG0504	CTP synthase activity
EVS87_RS17610	COG3343	RNA polymerase activity
EVS87_RS17625	COG1960	acyl-CoA dehydrogenase activity
EVS87_RS17630	COG1960	acyl-CoA dehydrogenase activity
EVS87_RS17635	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVS87_RS17640	COG0183	Belongs to the thiolase family
EVS87_RS17645	COG2181	nitrate reductase activity
EVS87_RS17645	COG0247	lactate metabolic process
EVS87_RS17650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_RS17655	COG4294	response to UV
EVS87_RS17665	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_RS17675	COG1132	(ABC) transporter
EVS87_RS17680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_RS17685	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_RS17695	COG0018	arginyl-trna synthetase
EVS87_RS17700	COG4506	Protein conserved in bacteria
EVS87_RS17710	COG0010	Belongs to the arginase family
EVS87_RS17715	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EVS87_RS17720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_RS17730	COG1994	Peptidase M50
EVS87_RS17735	COG1942	4-Oxalocrotonate Tautomerase
EVS87_RS17745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS17750	COG0583	DNA-binding transcription factor activity
EVS87_RS17755	COG0431	NADPH-dependent FMN reductase
EVS87_RS17760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS17765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EVS87_RS17770	COG0454	-acetyltransferase
EVS87_RS17775	COG0765	amino acid transport
EVS87_RS17785	COG0765	amino acid transport
EVS87_RS17790	COG1126	abc transporter atp-binding protein
EVS87_RS17795	COG3465	dGTPase activity
EVS87_RS17800	COG1078	dGTPase activity
EVS87_RS17805	COG4844	belongs to the
EVS87_RS17850	COG5444	nuclease activity
EVS87_RS17880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EVS87_RS17890	COG0280	phosphate acetyltransferase
EVS87_RS17900	COG2814	Major facilitator Superfamily
EVS87_RS17905	COG1522	sequence-specific DNA binding
EVS87_RS17910	COG2814	Major facilitator Superfamily
EVS87_RS17915	COG0077	Prephenate dehydratase
EVS87_RS17920	COG1917	Cupin 2, conserved barrel domain protein
EVS87_RS17925	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS17930	COG0151	Belongs to the GarS family
EVS87_RS17935	COG0436	Aminotransferase
EVS87_RS17940	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS17945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EVS87_RS17950	COG1091	dTDP-4-dehydrorhamnose reductase activity
EVS87_RS17955	COG1088	dTDP-glucose 4,6-dehydratase activity
EVS87_RS17960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EVS87_RS17965	COG3980	spore coat polysaccharide biosynthesis protein
EVS87_RS17970	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EVS87_RS17975	COG2089	acid synthase
EVS87_RS17980	COG0456	acetyltransferase
EVS87_RS17985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_RS17990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_RS17995	COG0463	Glycosyl transferase, family 2
EVS87_RS18015	COG2363	Small membrane protein
EVS87_RS18020	COG2233	PERMEase
EVS87_RS18030	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_RS18035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EVS87_RS18040	COG1216	Glycosyl transferase, family 2
EVS87_RS18050	COG0351	phosphomethylpyrimidine kinase
EVS87_RS18065	COG1621	beta-fructofuranosidase activity
EVS87_RS18070	COG1263	PTS System
EVS87_RS18070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS18075	COG3711	transcriptional antiterminator
EVS87_RS18085	COG1404	Belongs to the peptidase S8 family
EVS87_RS18095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_RS18100	COG0778	Nitroreductase
EVS87_RS18105	COG0772	Belongs to the SEDS family
EVS87_RS18115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EVS87_RS18120	COG1845	cytochrome c oxidase, subunit III
EVS87_RS18125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVS87_RS18130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVS87_RS18140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EVS87_RS18145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVS87_RS18150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EVS87_RS18165	COG2246	polysaccharide biosynthetic process
EVS87_RS18185	COG3162	membrane
EVS87_RS18190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_RS18200	COG0352	thiamine-phosphate diphosphorylase activity
EVS87_RS18205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EVS87_RS18210	COG0583	DNA-binding transcription factor activity
EVS87_RS18215	COG1380	Effector of murein hydrolase LrgA
EVS87_RS18220	COG1346	cytolysis
EVS87_RS18225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EVS87_RS18230	COG0346	lactoylglutathione lyase activity
EVS87_RS18240	COG0765	amino acid transport
EVS87_RS18245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_RS18255	COG0457	Tetratricopeptide repeat
EVS87_RS18260	COG2357	RelA SpoT domain protein
EVS87_RS18265	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS87_RS18270	COG1129	ABC transporter
EVS87_RS18280	COG3420	alginic acid biosynthetic process
EVS87_RS18285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_RS18300	COG1486	melibiose metabolic process
EVS87_RS18305	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_RS18310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS18315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS18320	COG3711	transcriptional antiterminator
EVS87_RS18320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS18335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_RS18350	COG1595	DNA-templated transcription, initiation
EVS87_RS18360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EVS87_RS18365	COG4988	ABC transporter
EVS87_RS18370	COG1294	oxidase, subunit
EVS87_RS18375	COG1271	oxidase subunit
EVS87_RS18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_RS18390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EVS87_RS18395	COG4509	Sortase family
EVS87_RS18420	COG5386	Cell surface protein
EVS87_RS18425	COG5386	Cell surface protein
EVS87_RS18430	COG1733	regulation of RNA biosynthetic process
EVS87_RS18435	COG2514	catechol 2,3-dioxygenase activity
EVS87_RS18440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS18440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_RS18445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_RS18445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_RS18455	COG0726	polysaccharide deacetylase
EVS87_RS18460	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_RS18465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS18470	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS18475	COG1312	Catalyzes the dehydration of D-mannonate
EVS87_RS18480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_RS18485	COG3711	transcriptional antiterminator
EVS87_RS18485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_RS18515	COG1027	Aspartate ammonia-lyase
EVS87_RS18520	COG0252	asparaginase activity
EVS87_RS18525	COG1396	sequence-specific DNA binding
EVS87_RS18550	COG4842	Belongs to the WXG100 family
EVS87_RS18555	COG2195	Cleaves the N-terminal amino acid of tripeptides
EVS87_RS18570	COG1737	Transcriptional regulator
EVS87_RS18575	COG2084	Dehydrogenase
EVS87_RS18585	COG2610	gluconate transmembrane transporter activity
EVS87_RS18590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVS87_RS18600	COG1136	(ABC) transporter
EVS87_RS18620	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS18625	COG2190	(PTS) system
EVS87_RS18625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS18625	COG1263	PTS System
EVS87_RS18630	COG3711	transcriptional antiterminator
EVS87_RS18635	COG3878	Protein conserved in bacteria
EVS87_RS18645	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_RS18650	COG1122	ATPase activity
EVS87_RS18655	COG4721	ABC-type cobalt transport system, permease component
EVS87_RS18660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVS87_RS18690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EVS87_RS18695	COG0778	Nitroreductase
EVS87_RS18700	COG1846	Transcriptional regulator
EVS87_RS18705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EVS87_RS18710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EVS87_RS18715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EVS87_RS18720	COG2390	Transcriptional regulator
EVS87_RS18730	COG2755	lipolytic protein G-D-S-L family
EVS87_RS18730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EVS87_RS18735	COG0477	Major facilitator Superfamily
EVS87_RS18740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVS87_RS18745	COG2226	methyltransferase
EVS87_RS18755	COG0561	phosphatase activity
EVS87_RS18760	COG0789	Transcriptional regulator
EVS87_RS18765	COG0673	inositol 2-dehydrogenase activity
EVS87_RS18770	COG0840	transmembrane signaling receptor activity
EVS87_RS18775	COG1113	amino acid transport
EVS87_RS18780	COG4335	DNA alkylation repair
EVS87_RS18790	COG1070	Carbohydrate kinase
EVS87_RS18795	COG1737	Transcriptional regulator
EVS87_RS18835	COG0583	DNA-binding transcription factor activity
EVS87_RS18840	COG1609	Transcriptional regulator
EVS87_RS18845	COG2182	Extracellular solute-binding protein
EVS87_RS18850	COG1175	transmembrane transport
EVS87_RS18855	COG3833	ABC-type maltose transport systems, permease component
EVS87_RS18865	COG1874	Beta-galactosidase
EVS87_RS18870	COG2851	Citrate transporter
EVS87_RS18880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EVS87_RS18885	COG1131	(ABC) transporter
EVS87_RS18890	COG2824	Alkylphosphonate utilization operon protein PhnA
EVS87_RS18895	COG1929	Belongs to the glycerate kinase type-1 family
EVS87_RS18900	COG2610	gluconate transmembrane transporter activity
EVS87_RS18905	COG3835	regulator
EVS87_RS18910	COG1309	transcriptional regulator
EVS87_RS18915	COG2814	Major facilitator Superfamily
EVS87_RS18925	COG1136	(ABC) transporter
EVS87_RS18940	COG3711	transcriptional antiterminator
EVS87_RS18945	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS18950	COG2190	(PTS) system
EVS87_RS18950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_RS18950	COG1263	PTS System
EVS87_RS18975	COG0494	nUDIX hydrolase
EVS87_RS18990	COG1113	amino acid transport
EVS87_RS18995	COG1609	Transcriptional regulator
EVS87_RS19000	COG2814	Major facilitator Superfamily
EVS87_RS19005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVS87_RS19010	COG2814	Major facilitator Superfamily
EVS87_RS19040	COG5444	nuclease activity
EVS87_RS19050	COG2723	6-phospho-beta-galactosidase activity
EVS87_RS19060	COG2188	Transcriptional regulator
EVS87_RS19070	COG0384	phenazine biosynthesis protein PhzF
EVS87_RS19075	COG0583	DNA-binding transcription factor activity
EVS87_RS19110	COG5002	protein histidine kinase activity
EVS87_RS19110	COG3850	Histidine kinase
EVS87_RS19120	COG2409	Drug exporters of the RND superfamily
EVS87_RS19125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_RS19150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EVS87_RS19155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EVS87_RS19165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_RS19175	COG4720	Psort location CytoplasmicMembrane, score
EVS87_RS19195	COG0456	acetyltransferase
EVS87_RS19200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_RS19205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EVS87_RS19210	COG4853	Protein conserved in bacteria
EVS87_RS19215	COG4863	YycH protein
EVS87_RS19220	COG5002	protein histidine kinase activity
EVS87_RS19225	COG0745	RESPONSE REGULATOR receiver
EVS87_RS19250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVS87_RS19260	COG2311	Membrane
EVS87_RS19265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EVS87_RS19270	COG1309	transcriptional regulator
EVS87_RS19275	COG2124	cytochrome p450
EVS87_RS19280	COG0346	lactoylglutathione lyase activity
EVS87_RS19285	COG0305	Participates in initiation and elongation during chromosome replication
EVS87_RS19300	COG2819	hydrolase of the alpha beta superfamily
EVS87_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_RS19310	COG1169	isochorismate synthase
EVS87_RS19315	COG1021	2,3-dihydroxybenzoate-AMP ligase
EVS87_RS19320	COG1535	isochorismatase
EVS87_RS19320	COG3433	isochorismatase activity
EVS87_RS19325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_RS19330	COG3251	PFAM MbtH domain protein
EVS87_RS19335	COG2207	Transcriptional regulator
EVS87_RS19335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS19340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_RS19345	COG2819	hydrolase of the alpha beta superfamily
EVS87_RS19350	COG3093	addiction module antidote protein HigA
EVS87_RS19355	COG2807	transmembrane transport
EVS87_RS19360	COG0359	binds to the 23S rRNA
EVS87_RS19365	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EVS87_RS19370	COG4241	membrane
EVS87_RS19375	COG1227	inorganic diphosphatase activity
EVS87_RS19385	COG1595	DNA-templated transcription, initiation
EVS87_RS19400	COG0655	NAD(P)H dehydrogenase (quinone) activity
EVS87_RS19405	COG0400	carboxylic ester hydrolase activity
EVS87_RS19410	COG0346	lactoylglutathione lyase activity
EVS87_RS19415	COG1174	glycine betaine transport
EVS87_RS19420	COG0517	IMP dehydrogenase activity
EVS87_RS19420	COG1125	glycine betaine transport
EVS87_RS19425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EVS87_RS19430	COG0629	single-stranded DNA binding
EVS87_RS19435	COG0360	Binds together with S18 to 16S ribosomal RNA
EVS87_RS19440	COG0012	GTP binding
EVS87_RS19445	COG4481	Protein conserved in bacteria
EVS87_RS19460	COG3949	Membrane
EVS87_RS19470	COG1475	DNA binding
EVS87_RS19475	COG1192	Involved in chromosome partitioning
EVS87_RS19485	COG1475	DNA binding
EVS87_RS19490	COG0357	Ribosomal RNA small subunit methyltransferase G
EVS87_RS19495	COG0445	tRNA wobble uridine modification
EVS87_RS19500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EVS87_RS19505	COG1847	R3H domain protein
EVS87_RS19510	COG0706	membrane insertase activity
EVS87_RS19515	COG0594	ribonuclease P activity
EVS87_RS19520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EVS87_RS19525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVS87_RS19530	COG0592	DNA-directed DNA polymerase activity
EVS87_RS19535	COG2501	S4 domain
EVS87_RS19540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EVS87_RS19550	COG0187	DNA topoisomerase II activity
EVS87_RS19555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS87_RS19590	COG0517	IMP dehydrogenase activity
EVS87_RS19590	COG0516	GMP reductase activity
EVS87_RS19595	COG1686	Belongs to the peptidase S11 family
EVS87_RS19600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_RS19605	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EVS87_RS19610	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EVS87_RS19615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EVS87_RS19620	COG0840	transmembrane signaling receptor activity
EVS87_RS19630	COG1428	Deoxynucleoside kinase
EVS87_RS19635	COG1428	Deoxynucleoside kinase
EVS87_RS19640	COG1388	LysM domain
EVS87_RS19640	COG3858	chitin binding
EVS87_RS19645	COG1335	isochorismatase
EVS87_RS19650	COG0590	tRNA wobble adenosine to inosine editing
EVS87_RS19660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EVS87_RS19665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EVS87_RS19670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EVS87_RS19715	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EVS87_RS19720	COG3853	Toxic anion resistance protein (TelA)
EVS87_RS19725	COG1982	Orn Lys Arg decarboxylase major
EVS87_RS19730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EVS87_RS19735	COG3870	Protein conserved in bacteria
EVS87_RS19740	COG1728	Protein conserved in bacteria
EVS87_RS19745	COG0470	DNA polymerase III
EVS87_RS19750	COG1774	PSP1 C-terminal conserved region
EVS87_RS19755	COG4467	Involved in initiation control of chromosome replication
EVS87_RS19760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EVS87_RS19765	COG2827	Endonuclease containing a URI domain
EVS87_RS19770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EVS87_RS19775	COG2002	toxin-antitoxin pair type II binding
EVS87_RS19785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_RS19785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_RS19790	COG0084	hydrolase, TatD family'
EVS87_RS19795	COG3584	3D domain protein
EVS87_RS19795	COG3583	domain protein
EVS87_RS19800	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EVS87_RS19805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EVS87_RS19815	COG4466	Protein conserved in bacteria
EVS87_RS19825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EVS87_RS19830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_RS19835	COG0251	oxidation-reduction process
EVS87_RS19840	COG2088	sporulation resulting in formation of a cellular spore
EVS87_RS19850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EVS87_RS19855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EVS87_RS19860	COG0193	aminoacyl-tRNA hydrolase activity
EVS87_RS19870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EVS87_RS19875	COG2002	toxin-antitoxin pair type II binding
EVS87_RS19880	COG2244	polysaccharide biosynthetic process
EVS87_RS19885	COG3956	TIGRFAM MazG family protein
EVS87_RS19890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EVS87_RS19905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EVS87_RS19910	COG1098	S1 RNA binding domain
EVS87_RS19925	COG2208	phosphoserine phosphatase activity
EVS87_RS19930	COG2304	oxidoreductase activity
EVS87_RS19935	COG0515	serine threonine protein kinase
EVS87_RS19940	COG0037	tRNA processing
EVS87_RS19945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EVS87_RS19950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVS87_RS19955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EVS87_RS19960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EVS87_RS19965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVS87_RS19970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_RS19975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EVS87_RS19980	COG0512	Glutamine amidotransferase of anthranilate synthase
EVS87_RS19985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_RS19990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EVS87_RS19995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EVS87_RS20000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EVS87_RS20005	COG1396	sequence-specific DNA binding
EVS87_RS20010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVS87_RS20015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family