locus-tag	class	description
JKL50_RS00020	COG2226	methyltransferase
JKL50_RS00025	COG1063	alcohol dehydrogenase
JKL50_RS00030	COG1131	(ABC) transporter
JKL50_RS00035	COG0842	Transport permease protein
JKL50_RS00035	COG1511	domain protein
JKL50_RS00040	COG0842	Transport permease protein
JKL50_RS00045	COG0583	DNA-binding transcription factor activity
JKL50_RS00050	COG1115	amino acid carrier protein
JKL50_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS00070	COG1063	alcohol dehydrogenase
JKL50_RS00080	COG0765	amino acid transport
JKL50_RS00085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS00090	COG1126	abc transporter atp-binding protein
JKL50_RS00095	COG1960	acyl-CoA dehydrogenase activity
JKL50_RS00100	COG2602	Beta-lactamase
JKL50_RS00165	COG0657	acetylesterase activity
JKL50_RS00170	COG1733	regulation of RNA biosynthetic process
JKL50_RS00175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JKL50_RS00180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JKL50_RS00190	COG1846	Transcriptional regulator
JKL50_RS00200	COG1609	Transcriptional regulator
JKL50_RS00215	COG2160	L-arabinose isomerase activity
JKL50_RS00240	COG1131	(ABC) transporter
JKL50_RS00275	COG0726	polysaccharide deacetylase
JKL50_RS00305	COG2856	Zn peptidase
JKL50_RS00315	COG0457	Tetratricopeptide repeat
JKL50_RS00325	COG2755	lipolytic protein G-D-S-L family
JKL50_RS00340	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JKL50_RS00345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JKL50_RS00350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JKL50_RS00355	COG1534	Rna-binding protein
JKL50_RS00360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JKL50_RS00365	COG1713	HD superfamily hydrolase involved in NAD metabolism
JKL50_RS00370	COG0799	negative regulation of ribosome biogenesis
JKL50_RS00375	COG2226	methyltransferase
JKL50_RS00380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JKL50_RS00385	COG1555	photosystem II stabilization
JKL50_RS00385	COG1596	polysaccharide export
JKL50_RS00390	COG2131	deaminase
JKL50_RS00395	COG2333	competence protein COMEC
JKL50_RS00395	COG0658	competence protein
JKL50_RS00405	COG1466	dna polymerase III delta subunit
JKL50_RS00410	COG0268	Binds directly to 16S ribosomal RNA
JKL50_RS00415	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JKL50_RS00420	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS00430	COG0481	GTPase activity
JKL50_RS00435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JKL50_RS00440	COG1420	regulation of RNA biosynthetic process
JKL50_RS00445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JKL50_RS00450	COG0443	Heat shock 70 kDa protein
JKL50_RS00455	COG0484	heat shock protein binding
JKL50_RS00460	COG2264	protein methyltransferase activity
JKL50_RS00465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JKL50_RS00470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JKL50_RS00475	COG1283	sodium-dependent phosphate transmembrane transporter activity
JKL50_RS00485	COG1610	YqeY-like protein
JKL50_RS00490	COG1030	water channel activity
JKL50_RS00495	COG4864	UPF0365 protein
JKL50_RS00510	COG0561	phosphatase activity
JKL50_RS00515	COG1702	phosphate starvation-inducible protein PhoH
JKL50_RS00520	COG1480	7TM receptor with intracellular HD hydrolase
JKL50_RS00525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JKL50_RS00530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JKL50_RS00535	COG0295	cytidine deaminase activity
JKL50_RS00540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JKL50_RS00550	COG1381	Involved in DNA repair and RecF pathway recombination
JKL50_RS00555	COG0752	glycyl-tRNA synthetase alpha subunit
JKL50_RS00560	COG0751	glycine-tRNA ligase activity
JKL50_RS00565	COG0517	IMP dehydrogenase activity
JKL50_RS00570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JKL50_RS00575	COG1671	Belongs to the UPF0178 family
JKL50_RS00580	COG0358	DNA primase activity
JKL50_RS00585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JKL50_RS00590	COG2010	Cytochrome c
JKL50_RS00595	COG2384	SAM-dependent methyltransferase
JKL50_RS00600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JKL50_RS00605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JKL50_RS00615	COG0513	Belongs to the DEAD box helicase family
JKL50_RS00630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JKL50_RS00635	COG1121	(ABC) transporter
JKL50_RS00640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JKL50_RS00645	COG0735	belongs to the Fur family
JKL50_RS00650	COG1940	carbohydrate kinase activity
JKL50_RS00655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JKL50_RS00660	COG4709	membrane
JKL50_RS00665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JKL50_RS00670	COG1388	LysM domain
JKL50_RS00675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKL50_RS00680	COG5521	maltodextrose utilization protein MalA
JKL50_RS00685	COG2839	Protein conserved in bacteria
JKL50_RS00690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JKL50_RS00695	COG0477	Major facilitator Superfamily
JKL50_RS00700	COG0768	penicillin binding
JKL50_RS00705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JKL50_RS00710	COG0573	inorganic phosphate transmembrane transporter activity
JKL50_RS00715	COG0581	inorganic phosphate transmembrane transporter activity
JKL50_RS00720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JKL50_RS00725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JKL50_RS00730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JKL50_RS00740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JKL50_RS00745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JKL50_RS00760	COG0705	Rhomboid family
JKL50_RS00760	COG0457	Tetratricopeptide repeat
JKL50_RS00765	COG4483	Protein conserved in bacteria
JKL50_RS00770	COG1940	carbohydrate kinase activity
JKL50_RS00775	COG1368	sulfuric ester hydrolase activity
JKL50_RS00780	COG2866	Carboxypeptidase
JKL50_RS00785	COG2814	Major facilitator Superfamily
JKL50_RS00790	COG0011	TIGRFAM Protein of
JKL50_RS00800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS00810	COG1393	Belongs to the ArsC family
JKL50_RS00820	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS00825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JKL50_RS00830	COG1459	type II secretion system
JKL50_RS00835	COG4537	Required for transformation and DNA binding
JKL50_RS00840	COG4970	Tfp pilus assembly protein FimT
JKL50_RS00870	COG0681	Belongs to the peptidase S26 family
JKL50_RS00895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKL50_RS00900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JKL50_RS00905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JKL50_RS00910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JKL50_RS00915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKL50_RS00920	COG0095	Lipoate-protein ligase
JKL50_RS00925	COG1321	iron dependent repressor
JKL50_RS00930	COG1752	Esterase of the alpha-beta hydrolase superfamily
JKL50_RS00940	COG3872	metal-dependent enzyme
JKL50_RS00950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JKL50_RS00955	COG0006	proline dipeptidase activity
JKL50_RS00960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JKL50_RS00970	COG3854	ATPases associated with a variety of cellular activities
JKL50_RS01010	COG0511	ligase activity, forming carbon-carbon bonds
JKL50_RS01015	COG0439	Biotin carboxylase
JKL50_RS01020	COG1302	Protein conserved in bacteria
JKL50_RS01025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKL50_RS01030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JKL50_RS01035	COG1570	exodeoxyribonuclease VII activity
JKL50_RS01040	COG1722	exodeoxyribonuclease VII activity
JKL50_RS01045	COG0142	geranyltranstransferase activity
JKL50_RS01050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JKL50_RS01055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JKL50_RS01060	COG1438	arginine binding
JKL50_RS01065	COG0497	DNA recombination
JKL50_RS01070	COG0750	zinc metalloprotease
JKL50_RS01080	COG0457	Tetratricopeptide repeat
JKL50_RS01085	COG0584	glycerophosphoryl diester phosphodiesterase
JKL50_RS01095	COG3829	transcription factor binding
JKL50_RS01095	COG3290	protein histidine kinase activity
JKL50_RS01100	COG0280	phosphate acetyltransferase
JKL50_RS01105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JKL50_RS01110	COG3426	butyrate kinase activity
JKL50_RS01115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKL50_RS01120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JKL50_RS01125	COG0022	dehydrogenase e1 component
JKL50_RS01130	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKL50_RS01140	COG1597	lipid kinase activity
JKL50_RS01150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS01155	COG0765	amino acid transport
JKL50_RS01160	COG1126	abc transporter atp-binding protein
JKL50_RS01165	COG4129	membrane
JKL50_RS01170	COG1376	ErfK ybiS ycfS ynhG family protein
JKL50_RS01180	COG0346	lactoylglutathione lyase activity
JKL50_RS01185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JKL50_RS01190	COG2195	Cleaves the N-terminal amino acid of tripeptides
JKL50_RS01195	COG0835	chemotaxis
JKL50_RS01200	COG0706	membrane insertase activity
JKL50_RS01210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKL50_RS01215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JKL50_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS01235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS01240	COG1447	Phosphotransferase system cellobiose-specific component IIA
JKL50_RS01245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS01250	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS01255	COG2188	Transcriptional regulator
JKL50_RS01260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JKL50_RS01270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS01275	COG0596	Alpha beta hydrolase
JKL50_RS01280	COG1902	pentaerythritol trinitrate reductase activity
JKL50_RS01285	COG4187	Peptidase family M20/M25/M40
JKL50_RS01295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JKL50_RS01300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS01305	COG0300	oxidoreductase activity
JKL50_RS01315	COG0446	pyridine nucleotide-disulphide oxidoreductase
JKL50_RS01320	COG1072	(Pantothenic acid kinase))
JKL50_RS01325	COG2211	Major facilitator Superfamily
JKL50_RS01335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JKL50_RS01345	COG0456	acetyltransferase
JKL50_RS01350	COG0456	acetyltransferase
JKL50_RS01350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JKL50_RS01355	COG4305	rare lipoprotein A
JKL50_RS01360	COG4918	Iron-sulphur cluster biosynthesis
JKL50_RS01370	COG0457	Tetratricopeptide repeat
JKL50_RS01375	COG1073	alpha beta
JKL50_RS01385	COG0667	Aldo Keto reductase
JKL50_RS01390	COG0494	nUDIX hydrolase
JKL50_RS01395	COG1379	DNA repair
JKL50_RS01400	COG2153	protein acetylation
JKL50_RS01410	COG1404	Belongs to the peptidase S8 family
JKL50_RS01415	COG1300	Membrane
JKL50_RS01420	COG0735	belongs to the Fur family
JKL50_RS01430	COG4974	Belongs to the 'phage' integrase family
JKL50_RS01435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JKL50_RS01440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JKL50_RS01445	COG1686	Belongs to the peptidase S11 family
JKL50_RS01455	COG2172	sigma factor antagonist activity
JKL50_RS01460	COG1191	sigma factor activity
JKL50_RS01480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKL50_RS01495	COG0697	spore germination
JKL50_RS01500	COG0019	diaminopimelate decarboxylase activity
JKL50_RS01505	COG4086	secreted protein
JKL50_RS01510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JKL50_RS01515	COG2814	Major facilitator Superfamily
JKL50_RS01535	COG0307	riboflavin synthase, alpha
JKL50_RS01540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS01540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS01545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JKL50_RS01550	COG0456	acetyltransferase
JKL50_RS01555	COG1547	Domain of unknown function (DUF309)
JKL50_RS01565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JKL50_RS01570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JKL50_RS01580	COG1686	Belongs to the peptidase S11 family
JKL50_RS01585	COG2715	membrane protein required for spore maturation
JKL50_RS01590	COG0700	Nucleoside recognition
JKL50_RS01595	COG1187	pseudouridine synthase activity
JKL50_RS01600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS01605	COG1333	cytochrome c biogenesis protein
JKL50_RS01610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JKL50_RS01615	COG0745	RESPONSE REGULATOR receiver
JKL50_RS01620	COG5002	protein histidine kinase activity
JKL50_RS01625	COG1595	DNA-templated transcription, initiation
JKL50_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JKL50_RS01645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JKL50_RS01650	COG1141	Ferredoxin
JKL50_RS01655	COG4955	Helix-turn-helix domain
JKL50_RS01660	COG0514	ATP-dependent DNA helicase (RecQ)
JKL50_RS01665	COG1266	CAAX protease self-immunity
JKL50_RS01670	COG1388	LysM domain
JKL50_RS01680	COG1408	metallophosphoesterase
JKL50_RS01685	COG4862	establishment of competence for transformation
JKL50_RS01690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JKL50_RS01695	COG0492	ferredoxin-NADP+ reductase activity
JKL50_RS01700	COG2339	peptidase activity
JKL50_RS01705	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS01705	COG3773	Cell wall hydrolase
JKL50_RS01710	COG2959	enzyme of heme biosynthesis
JKL50_RS01715	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JKL50_RS01725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JKL50_RS01735	COG1304	FMN binding
JKL50_RS01760	COG1160	GTP binding
JKL50_RS01765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JKL50_RS01780	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JKL50_RS01785	COG0776	regulation of translation
JKL50_RS01790	COG0302	gtp cyclohydrolase
JKL50_RS01800	COG0142	geranyltranstransferase activity
JKL50_RS01805	COG2226	methyltransferase
JKL50_RS01810	COG0142	geranyltranstransferase activity
JKL50_RS01815	COG0105	UTP biosynthetic process
JKL50_RS01820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JKL50_RS01825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JKL50_RS01830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JKL50_RS01835	COG4401	Chorismate mutase type I
JKL50_RS01845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JKL50_RS01850	COG0134	indole-3-glycerol-phosphate synthase activity
JKL50_RS01855	COG0135	phosphoribosylanthranilate isomerase activity
JKL50_RS01860	COG0133	tryptophan synthase activity
JKL50_RS01865	COG0159	tryptophan synthase activity
JKL50_RS01870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JKL50_RS01875	COG0287	Prephenate dehydrogenase
JKL50_RS01880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JKL50_RS01885	COG0457	Tetratricopeptide repeat
JKL50_RS01890	COG5582	Belongs to the UPF0302 family
JKL50_RS01900	COG0723	plastoquinol--plastocyanin reductase activity
JKL50_RS01905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JKL50_RS01910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JKL50_RS01910	COG2010	Cytochrome c
JKL50_RS01915	COG4347	Protein of unknown function (DUF1405)
JKL50_RS01925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JKL50_RS01930	COG1694	Mazg nucleotide pyrophosphohydrolase
JKL50_RS01935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JKL50_RS01940	COG1803	Methylglyoxal synthase
JKL50_RS01945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JKL50_RS01950	COG0438	transferase activity, transferring glycosyl groups
JKL50_RS01955	COG0617	tRNA 3'-terminal CCA addition
JKL50_RS01965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JKL50_RS01970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JKL50_RS01975	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JKL50_RS01980	COG1199	ATP-dependent helicase activity
JKL50_RS01980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JKL50_RS01990	COG5353	protein conserved in bacteria
JKL50_RS02000	COG3935	DnaD domain protein
JKL50_RS02005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JKL50_RS02015	COG4499	WXG100 protein secretion system (Wss), protein YukC
JKL50_RS02015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JKL50_RS02020	COG3331	DNA recombination
JKL50_RS02050	COG0071	Belongs to the small heat shock protein (HSP20) family
JKL50_RS02055	COG2190	(PTS) system
JKL50_RS02060	COG1902	pentaerythritol trinitrate reductase activity
JKL50_RS02065	COG1111	helicase
JKL50_RS02065	COG1205	dead DEAH box helicase
JKL50_RS02070	COG3359	exonuclease
JKL50_RS02080	COG4474	Belongs to the UPF0398 family
JKL50_RS02085	COG3599	regulation of cell shape
JKL50_RS02095	COG0116	Belongs to the methyltransferase superfamily
JKL50_RS02105	COG1199	ATP-dependent helicase activity
JKL50_RS02110	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JKL50_RS02115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKL50_RS02120	COG2233	PERMEase
JKL50_RS02125	COG0726	polysaccharide deacetylase
JKL50_RS02130	COG3424	synthase
JKL50_RS02135	COG1755	Isoprenylcysteine carboxyl methyltransferase
JKL50_RS02145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JKL50_RS02155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKL50_RS02165	COG0328	RNA-DNA hybrid ribonuclease activity
JKL50_RS02170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JKL50_RS02175	COG0328	RNA-DNA hybrid ribonuclease activity
JKL50_RS02190	COG1278	Cold shock
JKL50_RS02200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JKL50_RS02205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JKL50_RS02210	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JKL50_RS02215	COG0386	Belongs to the glutathione peroxidase family
JKL50_RS02220	COG1418	mRNA catabolic process
JKL50_RS02225	COG1413	lyase activity
JKL50_RS02230	COG0129	dihydroxy-acid dehydratase activity
JKL50_RS02240	COG2521	methyltransferase
JKL50_RS02240	COG2136	Putative SAM-dependent methyltransferase
JKL50_RS02250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JKL50_RS02255	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JKL50_RS02260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JKL50_RS02265	COG0204	Acyl-transferase
JKL50_RS02270	COG1272	protein, Hemolysin III
JKL50_RS02275	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JKL50_RS02280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JKL50_RS02295	COG1999	signal sequence binding
JKL50_RS02300	COG2755	lipolytic protein G-D-S-L family
JKL50_RS02305	COG4698	Protein conserved in bacteria
JKL50_RS02325	COG1846	Transcriptional regulator
JKL50_RS02330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKL50_RS02335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JKL50_RS02340	COG1086	Polysaccharide biosynthesis protein
JKL50_RS02350	COG4641	Protein conserved in bacteria
JKL50_RS02365	COG0463	Glycosyl transferase, family 2
JKL50_RS02370	COG3829	transcription factor binding
JKL50_RS02375	COG1509	lysine 2,3-aminomutase activity
JKL50_RS02385	COG4479	Belongs to the UPF0346 family
JKL50_RS02405	COG0671	phosphoesterase, PA-phosphatase related
JKL50_RS02415	COG0813	purine-nucleoside phosphorylase activity
JKL50_RS02420	COG1876	peptidase activity
JKL50_RS02430	COG2226	methyltransferase
JKL50_RS02435	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS02435	COG0793	Belongs to the peptidase S41A family
JKL50_RS02440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JKL50_RS02450	COG0778	Nitroreductase
JKL50_RS02455	COG1733	regulation of RNA biosynthetic process
JKL50_RS02470	COG2962	Rard protein
JKL50_RS02480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JKL50_RS02485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JKL50_RS02490	COG0534	Mate efflux family protein
JKL50_RS02495	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JKL50_RS02500	COG1388	LysM domain
JKL50_RS02500	COG0791	NLP P60 protein
JKL50_RS02505	COG2032	superoxide dismutase activity
JKL50_RS02510	COG0714	Associated with various cellular activities
JKL50_RS02515	COG4548	von Willebrand factor, type A
JKL50_RS02520	COG0567	Dehydrogenase, E1 component
JKL50_RS02525	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKL50_RS02530	COG0385	Bile acid
JKL50_RS02535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JKL50_RS02545	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS02570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JKL50_RS02580	COG0514	ATP-dependent DNA helicase (RecQ)
JKL50_RS02585	COG1388	LysM domain
JKL50_RS02585	COG3584	3D domain protein
JKL50_RS02595	COG2322	membrane
JKL50_RS02600	COG0372	Belongs to the citrate synthase family
JKL50_RS02605	COG2079	MmgE PrpD family protein
JKL50_RS02610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JKL50_RS02615	COG0741	lytic transglycosylase activity
JKL50_RS02620	COG0531	amino acid
JKL50_RS02625	COG0640	Transcriptional regulator
JKL50_RS02635	COG2378	regulation of single-species biofilm formation
JKL50_RS02640	COG3708	Transcriptional regulator
JKL50_RS02645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS02650	COG1309	transcriptional regulator
JKL50_RS02670	COG1994	Peptidase M50
JKL50_RS02675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKL50_RS02680	COG2211	Major facilitator Superfamily
JKL50_RS02690	COG1940	carbohydrate kinase activity
JKL50_RS02695	COG2115	Belongs to the xylose isomerase family
JKL50_RS02700	COG1070	Carbohydrate kinase
JKL50_RS02710	COG0243	molybdopterin cofactor binding
JKL50_RS02720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JKL50_RS02725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JKL50_RS02730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JKL50_RS02735	COG0454	-acetyltransferase
JKL50_RS02740	COG0789	Transcriptional regulator
JKL50_RS02740	COG4978	Transcriptional regulator
JKL50_RS02745	COG1132	(ABC) transporter
JKL50_RS02755	COG0583	DNA-binding transcription factor activity
JKL50_RS02760	COG0067	glutamate synthase
JKL50_RS02760	COG0069	glutamate synthase activity
JKL50_RS02760	COG0070	glutamate synthase
JKL50_RS02765	COG0493	'glutamate synthase
JKL50_RS02770	COG2323	membrane
JKL50_RS02775	COG4677	pectinesterase activity
JKL50_RS02780	COG2027	D-alanyl-D-alanine carboxypeptidase
JKL50_RS02785	COG0534	Mate efflux family protein
JKL50_RS02800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS02810	COG1587	Uroporphyrinogen-III synthase
JKL50_RS02815	COG0586	Pfam SNARE associated Golgi protein
JKL50_RS02820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JKL50_RS02830	COG0166	Belongs to the GPI family
JKL50_RS02850	COG0247	lactate metabolic process
JKL50_RS02855	COG0277	FAD linked oxidase domain protein
JKL50_RS02860	COG3835	regulator
JKL50_RS02870	COG1942	4-Oxalocrotonate Tautomerase
JKL50_RS02875	COG1349	DNA-binding transcription factor activity
JKL50_RS02880	COG2365	Tyrosine phosphatase family
JKL50_RS02885	COG1649	PFAM Uncharacterised BCR, COG1649
JKL50_RS02890	COG1960	acyl-CoA dehydrogenase activity
JKL50_RS02895	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS02900	COG0439	Biotin carboxylase
JKL50_RS02905	COG0511	ligase activity, forming carbon-carbon bonds
JKL50_RS02910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JKL50_RS02915	COG1024	Enoyl-CoA hydratase
JKL50_RS02920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JKL50_RS02925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKL50_RS02930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JKL50_RS02935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JKL50_RS02940	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS02960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKL50_RS02970	COG1105	Belongs to the carbohydrate kinase PfkB family
JKL50_RS02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS02980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS02980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS02980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS02990	COG2814	Major facilitator Superfamily
JKL50_RS02995	COG1846	Transcriptional regulator
JKL50_RS03005	COG5444	nuclease activity
JKL50_RS03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS03025	COG0456	acetyltransferase
JKL50_RS03035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS03050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JKL50_RS03055	COG1609	Transcriptional regulator
JKL50_RS03060	COG1653	transport
JKL50_RS03065	COG1175	transmembrane transport
JKL50_RS03070	COG0395	ABC-type sugar transport system, permease component
JKL50_RS03075	COG1486	melibiose metabolic process
JKL50_RS03080	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS03085	COG3507	Belongs to the glycosyl hydrolase 43 family
JKL50_RS03095	COG0745	RESPONSE REGULATOR receiver
JKL50_RS03100	COG2205	protein histidine kinase activity
JKL50_RS03115	COG2190	(PTS) system
JKL50_RS03115	COG1263	PTS System
JKL50_RS03115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS03120	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS03130	COG0657	acetylesterase activity
JKL50_RS03170	COG0251	oxidation-reduction process
JKL50_RS03175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JKL50_RS03180	COG1733	regulation of RNA biosynthetic process
JKL50_RS03185	COG2249	NAD(P)H dehydrogenase (quinone) activity
JKL50_RS03190	COG1309	transcriptional regulator
JKL50_RS03200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JKL50_RS03205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JKL50_RS03215	COG0640	Transcriptional regulator
JKL50_RS03220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JKL50_RS03225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JKL50_RS03230	COG0110	maltose O-acetyltransferase activity
JKL50_RS03235	COG0473	3-isopropylmalate dehydrogenase activity
JKL50_RS03240	COG0738	Major facilitator superfamily
JKL50_RS03250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JKL50_RS03255	COG0187	DNA topoisomerase II activity
JKL50_RS03260	COG1832	CoA-binding protein
JKL50_RS03265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JKL50_RS03270	COG4841	protein insertion into membrane
JKL50_RS03280	COG0824	Thioesterase
JKL50_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS03305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JKL50_RS03320	COG0071	Belongs to the small heat shock protein (HSP20) family
JKL50_RS03330	COG4846	Membrane protein involved in cytochrome C biogenesis
JKL50_RS03335	COG0785	Cytochrome C biogenesis protein
JKL50_RS03345	COG3763	UPF0154 protein
JKL50_RS03355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JKL50_RS03360	COG4224	UPF0291 protein
JKL50_RS03365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JKL50_RS03370	COG1388	LysM domain
JKL50_RS03375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JKL50_RS03390	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS03395	COG3209	COG3209 Rhs family protein
JKL50_RS03400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JKL50_RS03405	COG3591	Belongs to the peptidase S1B family
JKL50_RS03410	COG2124	cytochrome p450
JKL50_RS03410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JKL50_RS03415	COG1309	transcriptional regulator
JKL50_RS03420	COG2323	membrane
JKL50_RS03440	COG1556	Lactate utilization protein
JKL50_RS03445	COG1139	Iron-sulfur cluster binding protein
JKL50_RS03450	COG0247	lactate metabolic process
JKL50_RS03460	COG0702	epimerase
JKL50_RS03465	COG1959	2 iron, 2 sulfur cluster binding
JKL50_RS03475	COG4876	unkown
JKL50_RS03480	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JKL50_RS03485	COG3285	dna ligase
JKL50_RS03485	COG1793	dna ligase
JKL50_RS03490	COG3619	membrane
JKL50_RS03500	COG0457	Tetratricopeptide repeat
JKL50_RS03520	COG5646	InterPro IPR014922
JKL50_RS03545	COG5444	nuclease activity
JKL50_RS03555	COG0604	alcohol dehydrogenase
JKL50_RS03570	COG0457	Tetratricopeptide repeat
JKL50_RS03575	COG0494	nUDIX hydrolase
JKL50_RS03615	COG1404	Belongs to the peptidase S8 family
JKL50_RS03625	COG5632	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS03625	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS03630	COG4824	toxin secretion phage lysis holin
JKL50_RS03655	COG1705	Flagellar rod assembly protein muramidase FlgJ
JKL50_RS03655	COG1388	LysM domain
JKL50_RS03665	COG3953	SLT domain
JKL50_RS03665	COG5412	phage tail tape measure protein
JKL50_RS03890	COG4974	Belongs to the 'phage' integrase family
JKL50_RS03895	COG0174	glutamine synthetase
JKL50_RS03900	COG0789	Transcriptional regulator
JKL50_RS03905	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JKL50_RS03910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JKL50_RS03915	COG0464	growth
JKL50_RS03925	COG4112	unkown
JKL50_RS03930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKL50_RS03935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JKL50_RS03940	COG1780	Probably involved in ribonucleotide reductase function
JKL50_RS03955	COG1923	regulation of RNA biosynthetic process
JKL50_RS03960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JKL50_RS03990	COG1764	response to oxidative stress
JKL50_RS03995	COG4195	phage-related replication protein
JKL50_RS04000	COG1404	Belongs to the peptidase S8 family
JKL50_RS04005	COG0457	Tetratricopeptide repeat
JKL50_RS04010	COG4195	phage-related replication protein
JKL50_RS04015	COG1329	Transcriptional regulator
JKL50_RS04035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JKL50_RS04040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JKL50_RS04050	COG4550	Control of competence regulator ComK, YlbF/YmcA
JKL50_RS04055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JKL50_RS04060	COG0156	8-amino-7-oxononanoate synthase activity
JKL50_RS04065	COG1063	alcohol dehydrogenase
JKL50_RS04070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JKL50_RS04075	COG2359	stage V sporulation protein S
JKL50_RS04080	COG1692	metallophosphoesterase
JKL50_RS04085	COG1418	mRNA catabolic process
JKL50_RS04090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JKL50_RS04095	COG1546	Belongs to the CinA family
JKL50_RS04095	COG1058	Belongs to the CinA family
JKL50_RS04100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JKL50_RS04105	COG1426	Protein conserved in bacteria
JKL50_RS04120	COG0300	oxidoreductase activity
JKL50_RS04125	COG2409	Drug exporters of the RND superfamily
JKL50_RS04125	COG1033	growth of symbiont in host cell
JKL50_RS04135	COG0612	Peptidase, M16
JKL50_RS04140	COG0612	Peptidase, M16
JKL50_RS04145	COG2409	Drug exporters of the RND superfamily
JKL50_RS04145	COG1033	growth of symbiont in host cell
JKL50_RS04150	COG2814	Major facilitator Superfamily
JKL50_RS04155	COG2188	Transcriptional regulator
JKL50_RS04160	COG1674	ftsk spoiiie
JKL50_RS04160	COG4980	gas vesicle protein
JKL50_RS04170	COG0740	serine-type endopeptidase activity
JKL50_RS04175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JKL50_RS04185	COG0527	aspartate kinase activity
JKL50_RS04190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JKL50_RS04195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JKL50_RS04200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JKL50_RS04205	COG1873	PFAM PRC-barrel domain
JKL50_RS04210	COG0367	asparagine synthase
JKL50_RS04255	COG1260	myo-inositol-1-phosphate synthase
JKL50_RS04260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JKL50_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS04290	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
JKL50_RS04325	COG1132	(ABC) transporter
JKL50_RS04330	COG1132	(ABC) transporter
JKL50_RS04340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKL50_RS04345	COG0612	Peptidase, M16
JKL50_RS04350	COG0726	polysaccharide deacetylase
JKL50_RS04355	COG1185	polyribonucleotide nucleotidyltransferase activity
JKL50_RS04360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JKL50_RS04365	COG0196	riboflavin kinase activity
JKL50_RS04370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JKL50_RS04375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JKL50_RS04380	COG1550	Protein conserved in bacteria
JKL50_RS04385	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JKL50_RS04390	COG1358	cellular component organization or biogenesis
JKL50_RS04395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JKL50_RS04400	COG0195	Participates in both transcription termination and antitermination
JKL50_RS04405	COG0779	Required for maturation of 30S ribosomal subunits
JKL50_RS04415	COG3693	PFAM glycoside hydrolase, family 10
JKL50_RS04430	COG2176	DNA-directed DNA polymerase activity
JKL50_RS04435	COG0442	prolyl-tRNA aminoacylation
JKL50_RS04440	COG0750	zinc metalloprotease
JKL50_RS04445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JKL50_RS04450	COG4589	Belongs to the CDS family
JKL50_RS04455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JKL50_RS04460	COG0233	cytoplasmic translational termination
JKL50_RS04465	COG0528	UMP kinase activity
JKL50_RS04470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JKL50_RS04485	COG1191	sigma factor activity
JKL50_RS04495	COG1776	CheC inhibitor of MCP methylation
JKL50_RS04500	COG0835	chemotaxis
JKL50_RS04505	COG2198	Histidine kinase
JKL50_RS04505	COG0643	Histidine kinase
JKL50_RS04510	COG2201	protein-glutamate methylesterase activity
JKL50_RS04515	COG0455	bacterial-type flagellum organization
JKL50_RS04520	COG1419	protein localization to endoplasmic reticulum
JKL50_RS04525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JKL50_RS04530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JKL50_RS04535	COG1684	flagellar biosynthetic protein fliR
JKL50_RS04540	COG1987	bacterial-type flagellum assembly
JKL50_RS04545	COG1338	Plays a role in the flagellum-specific transport system
JKL50_RS04550	COG3190	flagellar
JKL50_RS04555	COG2201	protein-glutamate methylesterase activity
JKL50_RS04560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JKL50_RS04560	COG1776	CheC inhibitor of MCP methylation
JKL50_RS04565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JKL50_RS04570	COG1580	Controls the rotational direction of flagella during chemotaxis
JKL50_RS04575	COG1582	Flagellar protein (FlbD)
JKL50_RS04580	COG4786	Flagellar basal body rod
JKL50_RS04585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JKL50_RS04590	COG3144	bacterial-type flagellum assembly
JKL50_RS04595	COG3334	PFAM MgtE intracellular
JKL50_RS04600	COG2882	bacterial-type flagellum organization
JKL50_RS04605	COG1157	protein secretion by the type III secretion system
JKL50_RS04610	COG1317	bacterial-type flagellum organization
JKL50_RS04615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JKL50_RS04620	COG1766	The M ring may be actively involved in energy transduction
JKL50_RS04625	COG1677	Flagellar hook-basal body complex protein FliE
JKL50_RS04630	COG1558	bacterial-type flagellum-dependent cell motility
JKL50_RS04635	COG1815	bacterial-type flagellum-dependent cell motility
JKL50_RS04640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JKL50_RS04645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JKL50_RS04650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JKL50_RS04655	COG4974	Belongs to the 'phage' integrase family
JKL50_RS04660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JKL50_RS04665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JKL50_RS04670	COG0758	DNA mediated transformation
JKL50_RS04675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JKL50_RS04680	COG0045	succinate-CoA ligase (ADP-forming) activity
JKL50_RS04685	COG2257	FlhB HrpN YscU SpaS Family
JKL50_RS04695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JKL50_RS04700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JKL50_RS04705	COG0335	large ribosomal subunit rRNA binding
JKL50_RS04710	COG0336	Belongs to the RNA methyltransferase TrmD family
JKL50_RS04715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JKL50_RS04725	COG1837	Belongs to the UPF0109 family
JKL50_RS04730	COG0228	four-way junction DNA binding
JKL50_RS04735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JKL50_RS04740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JKL50_RS04745	COG0552	protein localization to endoplasmic reticulum
JKL50_RS04750	COG1196	nuclear chromosome segregation
JKL50_RS04760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKL50_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS04770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JKL50_RS04775	COG0416	fatty acid biosynthetic process
JKL50_RS04780	COG1349	DNA-binding transcription factor activity
JKL50_RS04785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JKL50_RS04790	COG1760	l-serine dehydratase
JKL50_RS04795	COG1760	l-serine dehydratase
JKL50_RS04800	COG1461	Dihydroxyacetone kinase
JKL50_RS04805	COG1302	Protein conserved in bacteria
JKL50_RS04810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JKL50_RS04820	COG1564	THIamine pyrophosphokinase
JKL50_RS04825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JKL50_RS04830	COG1162	GTPase activity
JKL50_RS04835	COG0515	serine threonine protein kinase
JKL50_RS04835	COG2815	serine threonine protein kinase
JKL50_RS04840	COG0631	protein serine/threonine phosphatase activity
JKL50_RS04845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JKL50_RS04850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JKL50_RS04850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JKL50_RS04855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JKL50_RS04860	COG0242	peptide deformylase activity
JKL50_RS04865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JKL50_RS04870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JKL50_RS04875	COG1758	RNA polymerase activity
JKL50_RS04880	COG0194	GDP metabolic process
JKL50_RS04885	COG2052	Domain of unknown function (DUF370)
JKL50_RS04890	COG1561	YicC-like family, N-terminal region
JKL50_RS04895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JKL50_RS04905	COG1648	precorrin-2 dehydrogenase activity
JKL50_RS04910	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JKL50_RS04915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JKL50_RS04920	COG0529	Catalyzes the synthesis of activated sulfate
JKL50_RS04925	COG2046	Belongs to the sulfate adenylyltransferase family
JKL50_RS04930	COG0306	phosphate transporter
JKL50_RS04935	COG0175	sulfate reduction
JKL50_RS04945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JKL50_RS04950	COG0284	orotidine-5'-phosphate decarboxylase activity
JKL50_RS04955	COG0167	dihydroorotate dehydrogenase activity
JKL50_RS04960	COG0543	2 iron, 2 sulfur cluster binding
JKL50_RS04965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JKL50_RS04970	COG0505	Belongs to the CarA family
JKL50_RS04975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JKL50_RS04980	COG0540	Belongs to the ATCase OTCase family
JKL50_RS04985	COG2233	PERMEase
JKL50_RS04990	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JKL50_RS04995	COG0564	pseudouridine synthase activity
JKL50_RS05000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JKL50_RS05005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JKL50_RS05010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JKL50_RS05015	COG3599	regulation of cell shape
JKL50_RS05020	COG2302	S4 RNA-binding domain
JKL50_RS05025	COG0762	integral membrane protein
JKL50_RS05030	COG1799	cell septum assembly
JKL50_RS05035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JKL50_RS05040	COG1496	oxidoreductase activity
JKL50_RS05045	COG1873	PFAM PRC-barrel domain
JKL50_RS05050	COG1119	ATPase activity
JKL50_RS05060	COG3732	PTS system glucitol sorbitol-specific
JKL50_RS05065	COG3730	PTS system glucitol sorbitol-specific
JKL50_RS05080	COG2390	Transcriptional regulator
JKL50_RS05085	COG1191	sigma factor activity
JKL50_RS05090	COG1191	sigma factor activity
JKL50_RS05100	COG1404	Belongs to the peptidase S8 family
JKL50_RS05100	COG4412	M6 family metalloprotease domain protein
JKL50_RS05105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JKL50_RS05110	COG0849	cell division
JKL50_RS05115	COG3856	small basic protein
JKL50_RS05120	COG3879	Bacterial protein of unknown function (DUF881)
JKL50_RS05125	COG3879	Bacterial protein of unknown function (DUF881)
JKL50_RS05130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JKL50_RS05135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JKL50_RS05140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JKL50_RS05145	COG0772	Belongs to the SEDS family
JKL50_RS05150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JKL50_RS05155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JKL50_RS05160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JKL50_RS05165	COG0768	penicillin binding
JKL50_RS05170	COG0768	penicillin binding
JKL50_RS05175	COG4839	cell division protein FtsL
JKL50_RS05180	COG0275	rRNA processing
JKL50_RS05185	COG2001	Belongs to the MraZ family
JKL50_RS05190	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JKL50_RS05195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JKL50_RS05200	COG0454	-acetyltransferase
JKL50_RS05210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JKL50_RS05215	COG1399	metal-binding, possibly nucleic acid-binding protein
JKL50_RS05225	COG3480	Lon protease (S16) C-terminal proteolytic domain
JKL50_RS05230	COG1752	Esterase of the alpha-beta hydrolase superfamily
JKL50_RS05235	COG3314	Sporulation integral membrane protein YlbJ
JKL50_RS05240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JKL50_RS05245	COG0742	ribosomal rna small subunit methyltransferase
JKL50_RS05250	COG4471	UPF0298 protein
JKL50_RS05255	COG3679	Belongs to the UPF0342 family
JKL50_RS05275	COG2340	Cysteine-rich secretory protein family
JKL50_RS05280	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JKL50_RS05290	COG3336	cytochrome c oxidase
JKL50_RS05295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JKL50_RS05300	COG1845	cytochrome c oxidase, subunit III
JKL50_RS05305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JKL50_RS05310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JKL50_RS05310	COG2010	Cytochrome c
JKL50_RS05315	COG0109	protoheme IX farnesyltransferase activity
JKL50_RS05320	COG1612	heme a metabolic process
JKL50_RS05325	COG0415	Belongs to the DNA photolyase family
JKL50_RS05330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JKL50_RS05335	COG0772	Belongs to the SEDS family
JKL50_RS05340	COG4838	Belongs to the UPF0358 family
JKL50_RS05345	COG2066	Belongs to the glutaminase family
JKL50_RS05350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JKL50_RS05355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JKL50_RS05365	COG4896	Protein conserved in bacteria
JKL50_RS05375	COG1217	gtp-binding protein TYPA
JKL50_RS05395	COG1595	DNA-templated transcription, initiation
JKL50_RS05410	COG0483	inositol monophosphate 1-phosphatase activity
JKL50_RS05420	COG4493	Belongs to the UPF0637 family
JKL50_RS05425	COG4476	Belongs to the UPF0223 family
JKL50_RS05430	COG1982	Orn Lys Arg decarboxylase major
JKL50_RS05440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS05445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKL50_RS05450	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKL50_RS05455	COG0022	dehydrogenase e1 component
JKL50_RS05460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JKL50_RS05475	COG0242	peptide deformylase activity
JKL50_RS05480	COG0561	phosphatase activity
JKL50_RS05485	COG5503	Protein of unknown function (DUF1447)
JKL50_RS05490	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JKL50_RS05495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JKL50_RS05500	COG0569	domain protein
JKL50_RS05505	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JKL50_RS05505	COG2105	PFAM AIG2 family protein
JKL50_RS05510	COG3852	Histidine kinase
JKL50_RS05515	COG2002	toxin-antitoxin pair type II binding
JKL50_RS05520	COG1077	Cell shape determining protein MreB Mrl
JKL50_RS05530	COG2309	aminopeptidase activity
JKL50_RS05535	COG0488	(ABC) transporter
JKL50_RS05545	COG0681	Belongs to the peptidase S26 family
JKL50_RS05550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS05550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS05550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS05555	COG1105	Belongs to the carbohydrate kinase PfkB family
JKL50_RS05560	COG1349	DNA-binding transcription factor activity
JKL50_RS05565	COG0577	efflux transmembrane transporter activity
JKL50_RS05570	COG1136	(ABC) transporter
JKL50_RS05575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JKL50_RS05590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JKL50_RS05595	COG0314	molybdopterin synthase activity
JKL50_RS05600	COG1763	Mo-molybdopterin cofactor biosynthetic process
JKL50_RS05605	COG0303	'Molybdopterin
JKL50_RS05610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JKL50_RS05615	COG0746	molybdenum cofactor guanylyltransferase activity
JKL50_RS05630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS05635	COG0450	alkyl hydroperoxide reductase
JKL50_RS05640	COG0668	transmembrane transport
JKL50_RS05650	COG1473	amidohydrolase
JKL50_RS05655	COG2171	N-acyltransferase activity
JKL50_RS05660	COG0716	FMN binding
JKL50_RS05670	COG0716	FMN binding
JKL50_RS05680	COG0583	DNA-binding transcription factor activity
JKL50_RS05685	COG0517	IMP dehydrogenase activity
JKL50_RS05695	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JKL50_RS05700	COG4703	Protein of unknown function (DUF1797)
JKL50_RS05705	COG3546	catalase activity
JKL50_RS05710	COG2200	EAL domain
JKL50_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS05720	COG1408	metallophosphoesterase
JKL50_RS05725	COG1376	ErfK ybiS ycfS ynhG family protein
JKL50_RS05730	COG2814	Major facilitator Superfamily
JKL50_RS05745	COG0697	spore germination
JKL50_RS05750	COG2207	Transcriptional regulator
JKL50_RS05750	COG1917	Cupin 2, conserved barrel domain protein
JKL50_RS05760	COG0835	chemotaxis
JKL50_RS05760	COG0784	Response regulator, receiver
JKL50_RS05770	COG1714	RDD family
JKL50_RS05780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JKL50_RS05785	COG0436	Aminotransferase
JKL50_RS05790	COG4191	Histidine kinase
JKL50_RS05795	COG0768	penicillin binding
JKL50_RS05800	COG2340	Cysteine-rich secretory protein family
JKL50_RS05805	COG2084	Dehydrogenase
JKL50_RS05815	COG0840	transmembrane signaling receptor activity
JKL50_RS05820	COG1533	DNA photolyase activity
JKL50_RS05830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JKL50_RS05835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS05840	COG2190	(PTS) system
JKL50_RS05840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS05840	COG1263	PTS System
JKL50_RS05845	COG3711	transcriptional antiterminator
JKL50_RS05850	COG1609	Transcriptional regulator
JKL50_RS05860	COG0006	proline dipeptidase activity
JKL50_RS05865	COG2217	Heavy metal translocating P-type atpase
JKL50_RS05870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS05875	COG2244	polysaccharide biosynthetic process
JKL50_RS05880	COG3773	Cell wall hydrolase
JKL50_RS05890	COG4873	Protein conserved in bacteria
JKL50_RS05900	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JKL50_RS05905	COG0602	queuosine metabolic process
JKL50_RS05910	COG0720	synthase
JKL50_RS05915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JKL50_RS05920	COG3949	Membrane
JKL50_RS05925	COG0542	response to heat
JKL50_RS05935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JKL50_RS05940	COG1360	Flagellar Motor Protein
JKL50_RS05945	COG1846	Transcriptional regulator
JKL50_RS05950	COG3852	Histidine kinase
JKL50_RS05960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JKL50_RS05965	COG0235	Class ii aldolase
JKL50_RS05970	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JKL50_RS05975	COG1850	ribulose-bisphosphate carboxylase activity
JKL50_RS05980	COG0436	Aminotransferase
JKL50_RS05985	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JKL50_RS05990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JKL50_RS05995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JKL50_RS06000	COG5002	protein histidine kinase activity
JKL50_RS06005	COG3594	Acyltransferase
JKL50_RS06020	COG2323	membrane
JKL50_RS06025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JKL50_RS06030	COG0501	Belongs to the peptidase M48B family
JKL50_RS06050	COG1191	sigma factor activity
JKL50_RS06055	COG0861	Integral membrane protein TerC family
JKL50_RS06060	COG0586	Pfam SNARE associated Golgi protein
JKL50_RS06065	COG3300	MHYT domain
JKL50_RS06065	COG5001	Diguanylate cyclase
JKL50_RS06070	COG1846	Transcriptional regulator
JKL50_RS06085	COG0789	Transcriptional regulator
JKL50_RS06095	COG0583	DNA-binding transcription factor activity
JKL50_RS06105	COG2239	Acts as a magnesium transporter
JKL50_RS06115	COG3212	peptidase
JKL50_RS06120	COG3212	peptidase
JKL50_RS06125	COG3850	Histidine kinase
JKL50_RS06125	COG5002	protein histidine kinase activity
JKL50_RS06130	COG0745	RESPONSE REGULATOR receiver
JKL50_RS06145	COG1404	Belongs to the peptidase S8 family
JKL50_RS06150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JKL50_RS06155	COG0590	tRNA wobble adenosine to inosine editing
JKL50_RS06160	COG1764	response to oxidative stress
JKL50_RS06165	COG1846	Transcriptional regulator
JKL50_RS06170	COG1764	response to oxidative stress
JKL50_RS06180	COG0457	Tetratricopeptide repeat
JKL50_RS06185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JKL50_RS06190	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JKL50_RS06195	COG0788	formyltetrahydrofolate deformylase activity
JKL50_RS06205	COG2076	Multidrug Resistance protein
JKL50_RS06210	COG2076	Multidrug Resistance protein
JKL50_RS06220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKL50_RS06235	COG1695	Transcriptional regulator
JKL50_RS06240	COG1607	acyl-coa hydrolase
JKL50_RS06245	COG1834	amidinotransferase
JKL50_RS06250	COG4608	Belongs to the ABC transporter superfamily
JKL50_RS06255	COG0791	NLP P60 protein
JKL50_RS06260	COG4948	Mandelate Racemase Muconate Lactonizing
JKL50_RS06265	COG1619	proteins homologs of microcin C7 resistance protein MccF
JKL50_RS06270	COG4166	transmembrane transport
JKL50_RS06275	COG0444	Belongs to the ABC transporter superfamily
JKL50_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKL50_RS06285	COG0601	transmembrane transport
JKL50_RS06290	COG2362	D-Aminopeptidase
JKL50_RS06295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JKL50_RS06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKL50_RS06305	COG0346	lactoylglutathione lyase activity
JKL50_RS06310	COG0531	amino acid
JKL50_RS06320	COG2390	Transcriptional regulator
JKL50_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS06335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JKL50_RS06340	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKL50_RS06345	COG0508	dehydrogenase complex catalyzes the overall conversion of
JKL50_RS06345	COG0022	dehydrogenase e1 component
JKL50_RS06350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JKL50_RS06355	COG1063	alcohol dehydrogenase
JKL50_RS06370	COG3775	system Galactitol-specific IIC component
JKL50_RS06380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JKL50_RS06385	COG4208	sulfate ABC transporter
JKL50_RS06395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JKL50_RS06400	COG0405	Gamma-glutamyltransferase
JKL50_RS06410	COG1392	Phosphate transport regulator
JKL50_RS06415	COG0306	phosphate transporter
JKL50_RS06430	COG5632	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS06430	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS06435	COG2856	Zn peptidase
JKL50_RS06440	COG4195	phage-related replication protein
JKL50_RS06460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS06465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS06470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS06475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS06485	COG1309	transcriptional regulator
JKL50_RS06495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JKL50_RS06520	COG2807	transmembrane transport
JKL50_RS06525	COG0583	DNA-binding transcription factor activity
JKL50_RS06545	COG0583	DNA-binding transcription factor activity
JKL50_RS06550	COG3173	Aminoglycoside phosphotransferase
JKL50_RS06565	COG0300	oxidoreductase activity
JKL50_RS06580	COG2364	Membrane
JKL50_RS06585	COG2153	protein acetylation
JKL50_RS06595	COG0457	Tetratricopeptide repeat
JKL50_RS06610	COG0825	malonyl-CoA metabolic process
JKL50_RS06615	COG0113	porphobilinogen synthase activity
JKL50_RS06660	COG3677	Transposase
JKL50_RS06680	COG0626	cystathionine gamma-synthase activity
JKL50_RS06685	COG0626	cystathionine gamma-synthase activity
JKL50_RS06690	COG2382	esterase
JKL50_RS06695	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JKL50_RS06700	COG2153	protein acetylation
JKL50_RS06710	COG0210	DNA helicase
JKL50_RS06765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JKL50_RS06770	COG0351	phosphomethylpyrimidine kinase
JKL50_RS06775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JKL50_RS06780	COG2022	thiamine diphosphate biosynthetic process
JKL50_RS06785	COG2104	thiamine diphosphate biosynthetic process
JKL50_RS06795	COG0352	thiamine-phosphate diphosphorylase activity
JKL50_RS06800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JKL50_RS06805	COG0475	glutathione-regulated potassium exporter activity
JKL50_RS06805	COG0569	domain protein
JKL50_RS06810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JKL50_RS06815	COG0564	pseudouridine synthase activity
JKL50_RS06820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JKL50_RS06825	COG2357	RelA SpoT domain protein
JKL50_RS06835	COG4116	CYTH
JKL50_RS06840	COG0741	lytic transglycosylase activity
JKL50_RS06845	COG2346	COG2346, Truncated hemoglobins
JKL50_RS06850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JKL50_RS06860	COG1164	Oligoendopeptidase f
JKL50_RS06870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKL50_RS06875	COG4862	establishment of competence for transformation
JKL50_RS06880	COG0861	Integral membrane protein TerC family
JKL50_RS06885	COG1393	Belongs to the ArsC family
JKL50_RS06890	COG0456	acetyltransferase
JKL50_RS06900	COG4608	Belongs to the ABC transporter superfamily
JKL50_RS06905	COG0444	Belongs to the ABC transporter superfamily
JKL50_RS06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKL50_RS06915	COG0601	transmembrane transport
JKL50_RS06920	COG4166	transmembrane transport
JKL50_RS06925	COG0180	Tryptophanyl-tRNA synthetase
JKL50_RS06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKL50_RS06940	COG0601	transmembrane transport
JKL50_RS06950	COG4608	Belongs to the ABC transporter superfamily
JKL50_RS06955	COG0444	Belongs to the ABC transporter superfamily
JKL50_RS06960	COG5504	Zn-dependent protease
JKL50_RS06965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKL50_RS06970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JKL50_RS06985	COG1744	ABC transporter substrate-binding protein PnrA-like
JKL50_RS06995	COG2267	carboxylic ester hydrolase activity
JKL50_RS07005	COG2814	Major facilitator Superfamily
JKL50_RS07015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JKL50_RS07020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JKL50_RS07025	COG0505	Belongs to the CarA family
JKL50_RS07030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JKL50_RS07035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JKL50_RS07040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JKL50_RS07045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JKL50_RS07050	COG2271	Major facilitator Superfamily
JKL50_RS07055	COG0277	FAD linked oxidase domain protein
JKL50_RS07060	COG2151	metal-sulfur cluster biosynthetic enzyme
JKL50_RS07065	COG1073	alpha beta
JKL50_RS07070	COG0561	phosphatase activity
JKL50_RS07090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JKL50_RS07095	COG1307	EDD domain protein, DegV family
JKL50_RS07100	COG0840	transmembrane signaling receptor activity
JKL50_RS07105	COG1744	ABC transporter substrate-binding protein PnrA-like
JKL50_RS07110	COG2996	Protein conserved in bacteria
JKL50_RS07115	COG1666	GTP binding
JKL50_RS07120	COG0646	methionine synthase
JKL50_RS07120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JKL50_RS07125	COG1410	methionine synthase
JKL50_RS07125	COG0646	methionine synthase
JKL50_RS07160	COG0076	glutamate decarboxylase activity
JKL50_RS07185	COG2207	Transcriptional regulator
JKL50_RS07185	COG1917	Cupin 2, conserved barrel domain protein
JKL50_RS07190	COG0534	Mate efflux family protein
JKL50_RS07195	COG1562	ergosterol biosynthetic process
JKL50_RS07210	COG0367	asparagine synthase
JKL50_RS07225	COG0179	Fumarylacetoacetate (FAA) hydrolase
JKL50_RS07235	COG5337	Spore coat protein CotH
JKL50_RS07275	COG1403	HNH endonuclease
JKL50_RS07280	COG0419	ATPase involved in DNA repair
JKL50_RS07285	COG0420	3'-5' exonuclease activity
JKL50_RS07290	COG1074	ATP-dependent DNA helicase activity
JKL50_RS07295	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JKL50_RS07300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JKL50_RS07305	COG2259	Doxx family
JKL50_RS07320	COG3180	Ammonia monooxygenase
JKL50_RS07325	COG0681	Belongs to the peptidase S26 family
JKL50_RS07330	COG0398	Pfam SNARE associated Golgi protein
JKL50_RS07345	COG1316	TRANSCRIPTIONal
JKL50_RS07350	COG4607	ABC-type enterochelin transport system periplasmic component
JKL50_RS07355	COG4604	ABC transporter, ATP-binding protein
JKL50_RS07360	COG4605	iron ion homeostasis
JKL50_RS07365	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS07370	COG2732	(Barnase) inhibitor
JKL50_RS07375	COG2814	Major facilitator Superfamily
JKL50_RS07380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS07395	COG4903	ComK protein
JKL50_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JKL50_RS07410	COG0723	plastoquinol--plastocyanin reductase activity
JKL50_RS07415	COG0840	transmembrane signaling receptor activity
JKL50_RS07420	COG0406	alpha-ribazole phosphatase activity
JKL50_RS07425	COG1404	Belongs to the peptidase S8 family
JKL50_RS07430	COG0501	Belongs to the peptidase M48B family
JKL50_RS07440	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS07445	COG0095	Lipoate-protein ligase
JKL50_RS07450	COG1234	tRNA 3'-trailer cleavage
JKL50_RS07460	COG1301	dicarboxylic acid transport
JKL50_RS07465	COG1363	Peptidase, m42
JKL50_RS07470	COG1511	domain protein
JKL50_RS07475	COG1309	transcriptional regulator
JKL50_RS07480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JKL50_RS07485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JKL50_RS07490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JKL50_RS07495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JKL50_RS07500	COG2329	Antibiotic biosynthesis monooxygenase
JKL50_RS07510	COG1473	amidohydrolase
JKL50_RS07520	COG4473	ABC transporter
JKL50_RS07525	COG1131	(ABC) transporter
JKL50_RS07530	COG0537	adenosine 5'-monophosphoramidase activity
JKL50_RS07535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JKL50_RS07550	COG4980	gas vesicle protein
JKL50_RS07555	COG1846	Transcriptional regulator
JKL50_RS07580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JKL50_RS07590	COG3481	metal-dependent phosphohydrolase, HD sub domain
JKL50_RS07595	COG4717	serine-type aminopeptidase activity
JKL50_RS07600	COG0420	3'-5' exonuclease activity
JKL50_RS07610	COG1024	Enoyl-CoA hydratase
JKL50_RS07620	COG0490	domain, Protein
JKL50_RS07625	COG0475	glutathione-regulated potassium exporter activity
JKL50_RS07635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JKL50_RS07640	COG0561	phosphatase activity
JKL50_RS07645	COG3679	Belongs to the UPF0342 family
JKL50_RS07650	COG4399	Belongs to the UPF0754 family
JKL50_RS07655	COG0189	ligase activity
JKL50_RS07660	COG0189	ligase activity
JKL50_RS07670	COG2508	Transcriptional regulator
JKL50_RS07675	COG3842	ATPase activity
JKL50_RS07685	COG0702	epimerase
JKL50_RS07690	COG1132	(ABC) transporter
JKL50_RS07695	COG1132	(ABC) transporter
JKL50_RS07700	COG0589	response to stress
JKL50_RS07705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JKL50_RS07710	COG0726	polysaccharide deacetylase
JKL50_RS07715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JKL50_RS07720	COG0668	transmembrane transport
JKL50_RS07730	COG0584	glycerophosphoryl diester phosphodiesterase
JKL50_RS07735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JKL50_RS07750	COG1253	flavin adenine dinucleotide binding
JKL50_RS07755	COG0789	Transcriptional regulator
JKL50_RS07760	COG1253	flavin adenine dinucleotide binding
JKL50_RS07765	COG0204	Acyl-transferase
JKL50_RS07770	COG1595	DNA-templated transcription, initiation
JKL50_RS07785	COG0531	amino acid
JKL50_RS07790	COG1388	LysM domain
JKL50_RS07790	COG0791	NLP P60 protein
JKL50_RS07795	COG1785	Belongs to the alkaline phosphatase family
JKL50_RS07800	COG2719	SpoVR family
JKL50_RS07805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JKL50_RS07805	COG1017	nitric oxide dioxygenase activity
JKL50_RS07810	COG1959	2 iron, 2 sulfur cluster binding
JKL50_RS07815	COG0753	catalase activity
JKL50_RS07830	COG2197	response regulator
JKL50_RS07835	COG2203	Gaf domain
JKL50_RS07835	COG4585	Histidine kinase
JKL50_RS07840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JKL50_RS07845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JKL50_RS07850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JKL50_RS07855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JKL50_RS07860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JKL50_RS07865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JKL50_RS07870	COG3835	regulator
JKL50_RS07890	COG3153	acetyltransferase
JKL50_RS07890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JKL50_RS07895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JKL50_RS07905	COG0564	pseudouridine synthase activity
JKL50_RS07910	COG3764	Sortase (surface protein transpeptidase)
JKL50_RS07915	COG1525	nuclease
JKL50_RS07915	COG0737	Belongs to the 5'-nucleotidase family
JKL50_RS07915	COG4085	toxin activity
JKL50_RS07920	COG5002	protein histidine kinase activity
JKL50_RS07925	COG5577	PFAM Coat F domain
JKL50_RS07950	COG3706	GGDEF domain
JKL50_RS07955	COG1278	Cold shock
JKL50_RS07965	COG0655	NAD(P)H dehydrogenase (quinone) activity
JKL50_RS07970	COG2814	Major facilitator Superfamily
JKL50_RS07975	COG1566	PFAM secretion protein HlyD family protein
JKL50_RS07980	COG2718	Belongs to the UPF0229 family
JKL50_RS07985	COG2766	serine protein kinase
JKL50_RS07990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JKL50_RS08000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JKL50_RS08005	COG3382	B3 4 domain protein
JKL50_RS08035	COG1131	(ABC) transporter
JKL50_RS08045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS08050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JKL50_RS08055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JKL50_RS08060	COG1116	anion transmembrane transporter activity
JKL50_RS08070	COG2873	o-acetylhomoserine
JKL50_RS08075	COG0681	Belongs to the peptidase S26 family
JKL50_RS08080	COG1368	sulfuric ester hydrolase activity
JKL50_RS08240	COG0735	belongs to the Fur family
JKL50_RS08245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JKL50_RS08250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JKL50_RS08255	COG4129	membrane
JKL50_RS08260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKL50_RS08265	COG0601	transmembrane transport
JKL50_RS08270	COG0747	negative chemotaxis
JKL50_RS08275	COG4608	Belongs to the ABC transporter superfamily
JKL50_RS08280	COG0444	Belongs to the ABC transporter superfamily
JKL50_RS08285	COG1132	(ABC) transporter
JKL50_RS08290	COG3557	Belongs to the UPF0374 family
JKL50_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS08315	COG1194	a g-specific adenine glycosylase
JKL50_RS08320	COG1988	membrane-bound metal-dependent
JKL50_RS08330	COG1191	sigma factor activity
JKL50_RS08340	COG2140	Oxalate decarboxylase
JKL50_RS08355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JKL50_RS08360	COG4485	Bacterial membrane protein, YfhO
JKL50_RS08365	COG0463	Glycosyl transferase, family 2
JKL50_RS08390	COG2137	regulation of response to DNA damage stimulus
JKL50_RS08395	COG1090	epimerase
JKL50_RS08410	COG0778	Nitroreductase
JKL50_RS08430	COG0392	lysyltransferase activity
JKL50_RS08430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JKL50_RS08435	COG1846	Transcriptional regulator
JKL50_RS08465	COG1595	DNA-templated transcription, initiation
JKL50_RS08470	COG1742	UPF0060 membrane protein
JKL50_RS08475	COG1132	(ABC) transporter
JKL50_RS08480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS08485	COG2169	Transcriptional regulator
JKL50_RS08490	COG0492	ferredoxin-NADP+ reductase activity
JKL50_RS08495	COG2755	lipolytic protein G-D-S-L family
JKL50_RS08500	COG4637	Psort location Cytoplasmic, score
JKL50_RS08510	COG1309	transcriptional regulator
JKL50_RS08515	COG2076	Multidrug Resistance protein
JKL50_RS08520	COG2076	Multidrug Resistance protein
JKL50_RS08570	COG2814	Major facilitator Superfamily
JKL50_RS08575	COG0789	Transcriptional regulator
JKL50_RS08595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKL50_RS08600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JKL50_RS08610	COG0598	Magnesium transport protein CorA
JKL50_RS08620	COG0726	polysaccharide deacetylase
JKL50_RS08630	COG0535	radical SAM domain protein
JKL50_RS08635	COG0668	transmembrane transport
JKL50_RS08645	COG0217	transcriptional regulatory protein
JKL50_RS08655	COG0387	Pfam Sodium calcium exchanger
JKL50_RS08665	COG0477	Major facilitator Superfamily
JKL50_RS08670	COG1295	ribonuclease BN
JKL50_RS08675	COG4980	gas vesicle protein
JKL50_RS08680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JKL50_RS08685	COG1115	amino acid carrier protein
JKL50_RS08690	COG4840	Belongs to the UPF0435 family
JKL50_RS08695	COG0693	protein deglycase activity
JKL50_RS08700	COG0737	Belongs to the 5'-nucleotidase family
JKL50_RS08710	COG2188	Transcriptional regulator
JKL50_RS08715	COG0366	Alpha amylase catalytic
JKL50_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS08720	COG1263	PTS System
JKL50_RS08730	COG0840	transmembrane signaling receptor activity
JKL50_RS08735	COG0076	glutamate decarboxylase activity
JKL50_RS08740	COG1368	sulfuric ester hydrolase activity
JKL50_RS08755	COG3739	integral membrane protein
JKL50_RS08760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS08760	COG1263	PTS System
JKL50_RS08765	COG0024	Methionine aminopeptidase
JKL50_RS08780	COG2258	MOSC domain
JKL50_RS08785	COG1254	Belongs to the acylphosphatase family
JKL50_RS08795	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JKL50_RS08800	COG1695	Transcriptional regulator
JKL50_RS08805	COG3479	Phenolic acid decarboxylase
JKL50_RS08815	COG2851	Citrate transporter
JKL50_RS08820	COG3181	Tripartite tricarboxylate transporter family receptor
JKL50_RS08825	COG4565	transcriptional regulatory protein
JKL50_RS08830	COG3290	protein histidine kinase activity
JKL50_RS08840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKL50_RS08840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKL50_RS08850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JKL50_RS08855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS08855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS08875	COG2130	NADP-dependent
JKL50_RS08880	COG0513	Belongs to the DEAD box helicase family
JKL50_RS08885	COG0488	(ABC) transporter
JKL50_RS08890	COG2814	Major facilitator Superfamily
JKL50_RS08895	COG0789	Transcriptional regulator
JKL50_RS08900	COG1469	GTP cyclohydrolase I activity
JKL50_RS08905	COG0488	(ABC) transporter
JKL50_RS08910	COG0457	Tetratricopeptide repeat
JKL50_RS08910	COG0463	Glycosyl transferase, family 2
JKL50_RS08915	COG0531	amino acid
JKL50_RS08930	COG0071	Belongs to the small heat shock protein (HSP20) family
JKL50_RS08945	COG0471	metal ion transport
JKL50_RS08955	COG2223	nitrite transmembrane transporter activity
JKL50_RS08960	COG1442	glycosyl transferase family 8
JKL50_RS08965	COG1216	Glycosyl transferase, family 2
JKL50_RS08970	COG1442	glycosyl transferase family 8
JKL50_RS08975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKL50_RS08980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JKL50_RS09010	COG2211	Major facilitator Superfamily
JKL50_RS09020	COG1486	melibiose metabolic process
JKL50_RS09035	COG0492	ferredoxin-NADP+ reductase activity
JKL50_RS09040	COG1959	2 iron, 2 sulfur cluster binding
JKL50_RS09055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JKL50_RS09060	COG5444	nuclease activity
JKL50_RS09070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JKL50_RS09075	COG1597	lipid kinase activity
JKL50_RS09080	COG1957	nucleoside hydrolase
JKL50_RS09085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JKL50_RS09090	COG1309	transcriptional regulator
JKL50_RS09095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKL50_RS09100	COG0154	amidase activity
JKL50_RS09105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JKL50_RS09110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JKL50_RS09115	COG1285	pathogenesis
JKL50_RS09120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JKL50_RS09125	COG4851	CamS sex pheromone cAM373 precursor
JKL50_RS09130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JKL50_RS09135	COG0210	DNA helicase
JKL50_RS09140	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JKL50_RS09155	COG0069	glutamate synthase activity
JKL50_RS09165	COG4496	protein, YerC YecD
JKL50_RS09170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JKL50_RS09180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JKL50_RS09185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JKL50_RS09190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JKL50_RS09195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JKL50_RS09215	COG0151	Belongs to the GarS family
JKL50_RS09220	COG0138	bifunctional purine biosynthesis protein purh
JKL50_RS09225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JKL50_RS09230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JKL50_RS09235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JKL50_RS09240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JKL50_RS09245	COG0047	phosphoribosylformylglycinamidine synthase activity
JKL50_RS09250	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JKL50_RS09255	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JKL50_RS09260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JKL50_RS09265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JKL50_RS09270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JKL50_RS09280	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JKL50_RS09285	COG3064	Membrane
JKL50_RS09290	COG5583	Uncharacterized small protein (DUF2292)
JKL50_RS09300	COG2252	PERMEase
JKL50_RS09305	COG0583	DNA-binding transcription factor activity
JKL50_RS09310	COG2814	Major facilitator Superfamily
JKL50_RS09320	COG1595	DNA-templated transcription, initiation
JKL50_RS09350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JKL50_RS09360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JKL50_RS09365	COG0519	Catalyzes the synthesis of GMP from XMP
JKL50_RS09365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JKL50_RS09370	COG1305	Transglutaminase-like
JKL50_RS09375	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JKL50_RS09380	COG0714	Associated with various cellular activities
JKL50_RS09385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JKL50_RS09390	COG1113	amino acid transport
JKL50_RS09395	COG2132	Multicopper oxidase
JKL50_RS09405	COG0823	Involved in the tonB-independent uptake of proteins
JKL50_RS09410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JKL50_RS09435	COG1876	peptidase activity
JKL50_RS09440	COG2808	Putative FMN-binding domain
JKL50_RS09445	COG0456	acetyltransferase
JKL50_RS09450	COG1846	Transcriptional regulator
JKL50_RS09455	COG0459	protein refolding
JKL50_RS09460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JKL50_RS09465	COG1266	CAAX protease self-immunity
JKL50_RS09480	COG0805	protein transport
JKL50_RS09485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JKL50_RS09490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JKL50_RS09495	COG0315	cyclic pyranopterin monophosphate synthase activity
JKL50_RS09500	COG0488	(ABC) transporter
JKL50_RS09505	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JKL50_RS09510	COG0456	acetyltransferase
JKL50_RS09515	COG1214	PFAM Peptidase M22, glycoprotease
JKL50_RS09520	COG0802	atpase or kinase
JKL50_RS09525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JKL50_RS09565	COG1301	dicarboxylic acid transport
JKL50_RS09575	COG0697	spore germination
JKL50_RS09580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JKL50_RS09590	COG4122	O-methyltransferase activity
JKL50_RS09600	COG0456	acetyltransferase
JKL50_RS09610	COG1396	sequence-specific DNA binding
JKL50_RS09625	COG0778	Nitroreductase
JKL50_RS09630	COG1846	Transcriptional regulator
JKL50_RS09635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JKL50_RS09640	COG1309	transcriptional regulator
JKL50_RS09670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKL50_RS09685	COG2814	Major facilitator Superfamily
JKL50_RS09705	COG2267	carboxylic ester hydrolase activity
JKL50_RS09710	COG0252	asparaginase activity
JKL50_RS09720	COG4221	oxidoreductase activity
JKL50_RS09730	COG0657	acetylesterase activity
JKL50_RS09735	COG0477	Major facilitator Superfamily
JKL50_RS09755	COG0789	Transcriptional regulator
JKL50_RS09760	COG1064	alcohol dehydrogenase
JKL50_RS09765	COG1329	Transcriptional regulator
JKL50_RS09770	COG1278	Cold shock
JKL50_RS09835	COG3091	SprT-like family
JKL50_RS09845	COG2183	response to ionizing radiation
JKL50_RS09850	COG2208	phosphoserine phosphatase activity
JKL50_RS09855	COG1191	sigma factor activity
JKL50_RS09860	COG2172	sigma factor antagonist activity
JKL50_RS09865	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS09870	COG2208	phosphoserine phosphatase activity
JKL50_RS09875	COG2172	sigma factor antagonist activity
JKL50_RS09880	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS09885	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS09890	COG2337	Toxic component of a toxin-antitoxin (TA) module
JKL50_RS09895	COG0864	Transcriptional regulator
JKL50_RS09900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JKL50_RS09905	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JKL50_RS09910	COG0736	holo-[acyl-carrier-protein] synthase activity
JKL50_RS09915	COG0705	Rhomboid family
JKL50_RS09920	COG3428	Bacterial PH domain
JKL50_RS09925	COG3402	PFAM membrane-flanked domain
JKL50_RS09930	COG0513	Belongs to the DEAD box helicase family
JKL50_RS09945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JKL50_RS09950	COG1181	Belongs to the D-alanine--D-alanine ligase family
JKL50_RS09955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS09970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JKL50_RS09975	COG1131	(ABC) transporter
JKL50_RS09980	COG1301	dicarboxylic acid transport
JKL50_RS09985	COG0628	permease
JKL50_RS09990	COG1301	dicarboxylic acid transport
JKL50_RS09995	COG4565	transcriptional regulatory protein
JKL50_RS10000	COG3290	protein histidine kinase activity
JKL50_RS10005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JKL50_RS10010	COG2217	Heavy metal translocating P-type atpase
JKL50_RS10015	COG2261	transglycosylase associated protein
JKL50_RS10020	COG1914	H( )-stimulated, divalent metal cation uptake system
JKL50_RS10025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKL50_RS10045	COG5444	nuclease activity
JKL50_RS10050	COG0028	Belongs to the TPP enzyme family
JKL50_RS10055	COG0531	amino acid
JKL50_RS10065	COG1215	transferase activity, transferring glycosyl groups
JKL50_RS10070	COG5298	Protein conserved in bacteria
JKL50_RS10075	COG3706	GGDEF domain
JKL50_RS10080	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JKL50_RS10085	COG0551	DNA topoisomerase type I activity
JKL50_RS10085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JKL50_RS10090	COG0473	3-isopropylmalate dehydrogenase activity
JKL50_RS10095	COG0697	spore germination
JKL50_RS10100	COG1917	Cupin 2, conserved barrel domain protein
JKL50_RS10100	COG2207	Transcriptional regulator
JKL50_RS10105	COG1802	Transcriptional regulator
JKL50_RS10110	COG2814	Major facilitator Superfamily
JKL50_RS10130	COG3871	stress protein (general stress protein 26)
JKL50_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS10140	COG2226	methyltransferase
JKL50_RS10145	COG3711	transcriptional antiterminator
JKL50_RS10155	COG2755	lipolytic protein G-D-S-L family
JKL50_RS10160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JKL50_RS10165	COG1414	Transcriptional regulator
JKL50_RS10170	COG1984	allophanate hydrolase subunit 2
JKL50_RS10175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JKL50_RS10180	COG4336	lyase activity
JKL50_RS10185	COG1914	H( )-stimulated, divalent metal cation uptake system
JKL50_RS10190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JKL50_RS10195	COG0561	phosphatase activity
JKL50_RS10205	COG0346	lactoylglutathione lyase activity
JKL50_RS10240	COG0840	transmembrane signaling receptor activity
JKL50_RS10245	COG0246	Mannitol dehydrogenase
JKL50_RS10250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS10255	COG2213	PTS system mannitol-specific
JKL50_RS10260	COG1276	copper resistance
JKL50_RS10260	COG2372	response to copper ion
JKL50_RS10265	COG4549	nuclear export factor GLE1
JKL50_RS10270	COG2249	NAD(P)H dehydrogenase (quinone) activity
JKL50_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS10280	COG0531	amino acid
JKL50_RS10285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JKL50_RS10290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS10295	COG0583	DNA-binding transcription factor activity
JKL50_RS10305	COG0640	Transcriptional regulator
JKL50_RS10315	COG1309	transcriptional regulator
JKL50_RS10320	COG2814	Major facilitator Superfamily
JKL50_RS10325	COG0527	aspartate kinase activity
JKL50_RS10330	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS10335	COG3850	Histidine kinase
JKL50_RS10335	COG5002	protein histidine kinase activity
JKL50_RS10340	COG0745	RESPONSE REGULATOR receiver
JKL50_RS10345	COG2079	MmgE PrpD family protein
JKL50_RS10350	COG1473	amidohydrolase
JKL50_RS10355	COG1126	abc transporter atp-binding protein
JKL50_RS10360	COG0765	amino acid transport
JKL50_RS10365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS10370	COG0456	acetyltransferase
JKL50_RS10375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS10380	COG5434	Belongs to the glycosyl hydrolase 28 family
JKL50_RS10385	COG3104	oligopeptide transport
JKL50_RS10390	COG0833	amino acid
JKL50_RS10395	COG0412	Dienelactone hydrolase
JKL50_RS10400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS10405	COG0765	amino acid transport
JKL50_RS10410	COG1126	abc transporter atp-binding protein
JKL50_RS10415	COG2364	Membrane
JKL50_RS10425	COG3708	Transcriptional regulator
JKL50_RS10425	COG2207	Transcriptional regulator
JKL50_RS10435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS10440	COG0697	spore germination
JKL50_RS10445	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JKL50_RS10460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKL50_RS10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKL50_RS10470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKL50_RS10480	COG1176	ABC-type spermidine putrescine transport system, permease component I
JKL50_RS10485	COG3842	ATPase activity
JKL50_RS10505	COG3209	COG3209 Rhs family protein
JKL50_RS10510	COG3290	protein histidine kinase activity
JKL50_RS10510	COG0840	transmembrane signaling receptor activity
JKL50_RS10520	COG2746	aminoglycoside 3-N-acetyltransferase activity
JKL50_RS10525	COG1522	sequence-specific DNA binding
JKL50_RS10530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JKL50_RS10540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS10545	COG0765	amino acid transport
JKL50_RS10550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JKL50_RS10555	COG2508	Transcriptional regulator
JKL50_RS10560	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS10565	COG0506	proline dehydrogenase activity
JKL50_RS10570	COG3541	Predicted nucleotidyltransferase
JKL50_RS10580	COG3458	cephalosporin-C deacetylase activity
JKL50_RS10585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JKL50_RS10590	COG0583	DNA-binding transcription factor activity
JKL50_RS10595	COG2226	methyltransferase
JKL50_RS10600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JKL50_RS10615	COG2271	Major facilitator Superfamily
JKL50_RS10620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JKL50_RS10630	COG0028	Belongs to the TPP enzyme family
JKL50_RS10635	COG0710	3-dehydroquinate dehydratase activity
JKL50_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS10650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JKL50_RS10655	COG3665	Urea carboxylase-associated protein
JKL50_RS10660	COG1113	amino acid transport
JKL50_RS10665	COG3403	YqcI/YcgG family
JKL50_RS10680	COG1280	lysine exporter protein (LysE YggA)
JKL50_RS10685	COG0738	Major facilitator superfamily
JKL50_RS10690	COG0673	inositol 2-dehydrogenase activity
JKL50_RS10695	COG0561	phosphatase activity
JKL50_RS10700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JKL50_RS10705	COG1609	Transcriptional regulator
JKL50_RS10710	COG1620	l-lactate permease
JKL50_RS10715	COG0039	L-malate dehydrogenase activity
JKL50_RS10720	COG1288	antiporter activity
JKL50_RS10725	COG1473	amidohydrolase
JKL50_RS10740	COG2113	Glycine betaine
JKL50_RS10745	COG4176	ABC-type proline glycine betaine transport system permease component
JKL50_RS10750	COG4175	Glycine betaine
JKL50_RS10750	COG0517	IMP dehydrogenase activity
JKL50_RS10755	COG3853	Toxic anion resistance protein (TelA)
JKL50_RS10785	COG0861	Integral membrane protein TerC family
JKL50_RS10790	COG2310	stress, protein
JKL50_RS10795	COG2310	stress, protein
JKL50_RS10800	COG2310	stress, protein
JKL50_RS10805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS10820	COG3773	Cell wall hydrolase
JKL50_RS10840	COG1668	transmembrane transport
JKL50_RS10845	COG4555	ABC transporter
JKL50_RS10850	COG3279	Response regulator of the LytR AlgR family
JKL50_RS10855	COG3290	protein histidine kinase activity
JKL50_RS10860	COG0667	Aldo Keto reductase
JKL50_RS10870	COG3012	SEC-C Motif Domain Protein
JKL50_RS10870	COG1405	negative regulation of cell septum assembly
JKL50_RS10875	COG0784	Response regulator, receiver
JKL50_RS10880	COG4191	Histidine kinase
JKL50_RS10885	COG2066	Belongs to the glutaminase family
JKL50_RS10890	COG1115	amino acid carrier protein
JKL50_RS10895	COG0596	Alpha beta hydrolase
JKL50_RS10905	COG0531	amino acid
JKL50_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS10915	COG1846	Transcriptional regulator
JKL50_RS10920	COG1917	Cupin 2, conserved barrel domain protein
JKL50_RS10925	COG1309	transcriptional regulator
JKL50_RS10935	COG1404	Belongs to the peptidase S8 family
JKL50_RS10950	COG0456	acetyltransferase
JKL50_RS10955	COG2814	Major facilitator Superfamily
JKL50_RS10975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JKL50_RS10980	COG2040	homocysteine
JKL50_RS10985	COG0833	amino acid
JKL50_RS11000	COG1404	Belongs to the peptidase S8 family
JKL50_RS11005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS11005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS11010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS11015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JKL50_RS11020	COG0383	alpha-mannosidase activity
JKL50_RS11025	COG1940	carbohydrate kinase activity
JKL50_RS11030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS11030	COG3711	transcriptional antiterminator
JKL50_RS11055	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS11060	COG2190	(PTS) system
JKL50_RS11060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS11060	COG1263	PTS System
JKL50_RS11065	COG3711	transcriptional antiterminator
JKL50_RS11075	COG0531	amino acid
JKL50_RS11080	COG1054	Belongs to the UPF0176 family
JKL50_RS11085	COG0371	Dehydrogenase
JKL50_RS11090	COG0656	L-ascorbic acid biosynthetic process
JKL50_RS11100	COG1683	Conserved Protein
JKL50_RS11105	COG1846	Transcriptional regulator
JKL50_RS11120	COG2814	Major facilitator Superfamily
JKL50_RS11125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JKL50_RS11135	COG0730	response to heat
JKL50_RS11140	COG0425	Belongs to the sulfur carrier protein TusA family
JKL50_RS11145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS11145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKL50_RS11150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKL50_RS11150	COG0425	Belongs to the sulfur carrier protein TusA family
JKL50_RS11160	COG2210	Belongs to the sulfur carrier protein TusA family
JKL50_RS11165	COG1937	Protein conserved in bacteria
JKL50_RS11180	COG0640	Transcriptional regulator
JKL50_RS11195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JKL50_RS11200	COG1331	Highly conserved protein containing a thioredoxin domain
JKL50_RS11210	COG2271	Major facilitator Superfamily
JKL50_RS11215	COG0584	glycerophosphoryl diester phosphodiesterase
JKL50_RS11220	COG1113	amino acid transport
JKL50_RS11235	COG1309	transcriptional regulator
JKL50_RS11240	COG2207	Transcriptional regulator
JKL50_RS11245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JKL50_RS11255	COG1476	TRANSCRIPTIONal
JKL50_RS11275	COG2311	Membrane
JKL50_RS11285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS11290	COG1413	lyase activity
JKL50_RS11300	COG1131	(ABC) transporter
JKL50_RS11310	COG1695	Transcriptional regulator
JKL50_RS11320	COG1136	(ABC) transporter
JKL50_RS11320	COG0577	efflux transmembrane transporter activity
JKL50_RS11330	COG1131	(ABC) transporter
JKL50_RS11350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JKL50_RS11355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JKL50_RS11360	COG4856	YbbR-like protein
JKL50_RS11365	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JKL50_RS11370	COG5662	AntiSigma factor
JKL50_RS11375	COG1595	DNA-templated transcription, initiation
JKL50_RS11410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JKL50_RS11415	COG1737	Transcriptional regulator
JKL50_RS11420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS11420	COG1263	PTS System
JKL50_RS11425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JKL50_RS11430	COG1472	Belongs to the glycosyl hydrolase 3 family
JKL50_RS11435	COG3876	Protein conserved in bacteria
JKL50_RS11440	COG0385	Bile acid
JKL50_RS11445	COG0659	secondary active sulfate transmembrane transporter activity
JKL50_RS11450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS11480	COG0726	polysaccharide deacetylase
JKL50_RS11485	COG2194	sulfuric ester hydrolase activity
JKL50_RS11495	COG0489	protein tyrosine kinase activity
JKL50_RS11500	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS11530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JKL50_RS11535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JKL50_RS11540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JKL50_RS11545	COG0101	tRNA pseudouridine synthase activity
JKL50_RS11550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKL50_RS11555	COG1122	ATPase activity
JKL50_RS11560	COG1122	ATPase activity
JKL50_RS11565	COG0203	ribosomal protein L17
JKL50_RS11570	COG0202	RNA polymerase activity
JKL50_RS11575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JKL50_RS11580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JKL50_RS11585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JKL50_RS11590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JKL50_RS11595	COG0024	Methionine aminopeptidase
JKL50_RS11600	COG0563	adenylate kinase activity
JKL50_RS11605	COG0201	protein transport
JKL50_RS11610	COG0200	Binds to the 23S rRNA
JKL50_RS11615	COG1841	ribosomal large subunit assembly
JKL50_RS11620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JKL50_RS11625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JKL50_RS11630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JKL50_RS11635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JKL50_RS11640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JKL50_RS11645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JKL50_RS11650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JKL50_RS11655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JKL50_RS11660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JKL50_RS11665	COG0255	Belongs to the universal ribosomal protein uL29 family
JKL50_RS11670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JKL50_RS11675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JKL50_RS11680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JKL50_RS11685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JKL50_RS11690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JKL50_RS11695	COG0089	rRNA binding
JKL50_RS11700	COG0088	Forms part of the polypeptide exit tunnel
JKL50_RS11705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JKL50_RS11715	COG0596	Alpha beta hydrolase
JKL50_RS11720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JKL50_RS11725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JKL50_RS11730	COG0049	tRNA binding
JKL50_RS11735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JKL50_RS11740	COG1358	cellular component organization or biogenesis
JKL50_RS11745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JKL50_RS11750	COG0085	RNA polymerase activity
JKL50_RS11755	COG2813	Specifically methylates the guanine in position
JKL50_RS11760	COG0222	ribosome binding
JKL50_RS11765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JKL50_RS11770	COG0081	regulation of translation
JKL50_RS11780	COG0250	Participates in transcription elongation, termination and antitermination
JKL50_RS11785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JKL50_RS11790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JKL50_RS11795	COG1595	DNA-templated transcription, initiation
JKL50_RS11800	COG3688	RNA-binding protein containing a PIN domain
JKL50_RS11805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JKL50_RS11810	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JKL50_RS11815	COG0215	cysteine-tRNA ligase activity
JKL50_RS11820	COG1045	serine acetyltransferase
JKL50_RS11825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JKL50_RS11830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JKL50_RS11835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JKL50_RS11840	COG4956	integral membrane protein (PIN domain superfamily)
JKL50_RS11845	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JKL50_RS11850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JKL50_RS11855	COG0542	response to heat
JKL50_RS11860	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JKL50_RS11865	COG3880	PFAM UvrB UvrC protein
JKL50_RS11870	COG4463	regulation of RNA biosynthetic process
JKL50_RS11950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JKL50_RS11955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JKL50_RS11960	COG1396	sequence-specific DNA binding
JKL50_RS11965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JKL50_RS11970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JKL50_RS11975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JKL50_RS11980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JKL50_RS11985	COG0512	Glutamine amidotransferase of anthranilate synthase
JKL50_RS11990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JKL50_RS11995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JKL50_RS12000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JKL50_RS12005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JKL50_RS12010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JKL50_RS12015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JKL50_RS12020	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JKL50_RS12025	COG0037	tRNA processing
JKL50_RS12030	COG0515	serine threonine protein kinase
JKL50_RS12035	COG2304	oxidoreductase activity
JKL50_RS12040	COG2208	phosphoserine phosphatase activity
JKL50_RS12055	COG1098	S1 RNA binding domain
JKL50_RS12060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JKL50_RS12075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JKL50_RS12080	COG3956	TIGRFAM MazG family protein
JKL50_RS12085	COG2244	polysaccharide biosynthetic process
JKL50_RS12090	COG2002	toxin-antitoxin pair type II binding
JKL50_RS12095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JKL50_RS12105	COG0193	aminoacyl-tRNA hydrolase activity
JKL50_RS12110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JKL50_RS12115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JKL50_RS12125	COG2088	sporulation resulting in formation of a cellular spore
JKL50_RS12130	COG0251	oxidation-reduction process
JKL50_RS12135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKL50_RS12140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JKL50_RS12150	COG4466	Protein conserved in bacteria
JKL50_RS12160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JKL50_RS12165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JKL50_RS12170	COG3583	domain protein
JKL50_RS12170	COG3584	3D domain protein
JKL50_RS12175	COG0084	hydrolase, TatD family'
JKL50_RS12180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKL50_RS12180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKL50_RS12185	COG2002	toxin-antitoxin pair type II binding
JKL50_RS12190	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JKL50_RS12195	COG2827	Endonuclease containing a URI domain
JKL50_RS12200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JKL50_RS12205	COG4467	Involved in initiation control of chromosome replication
JKL50_RS12210	COG1774	PSP1 C-terminal conserved region
JKL50_RS12215	COG0470	DNA polymerase III
JKL50_RS12220	COG1728	Protein conserved in bacteria
JKL50_RS12225	COG3870	Protein conserved in bacteria
JKL50_RS12230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JKL50_RS12235	COG1982	Orn Lys Arg decarboxylase major
JKL50_RS12240	COG3853	Toxic anion resistance protein (TelA)
JKL50_RS12245	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JKL50_RS12290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JKL50_RS12295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JKL50_RS12300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JKL50_RS12310	COG0590	tRNA wobble adenosine to inosine editing
JKL50_RS12315	COG1335	isochorismatase
JKL50_RS12320	COG3858	chitin binding
JKL50_RS12320	COG1388	LysM domain
JKL50_RS12325	COG1428	Deoxynucleoside kinase
JKL50_RS12330	COG1428	Deoxynucleoside kinase
JKL50_RS12340	COG0840	transmembrane signaling receptor activity
JKL50_RS12345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JKL50_RS12350	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JKL50_RS12355	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JKL50_RS12360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JKL50_RS12365	COG1686	Belongs to the peptidase S11 family
JKL50_RS12370	COG0517	IMP dehydrogenase activity
JKL50_RS12370	COG0516	GMP reductase activity
JKL50_RS12405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JKL50_RS12410	COG0187	DNA topoisomerase II activity
JKL50_RS12420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JKL50_RS12425	COG2501	S4 domain
JKL50_RS12430	COG0592	DNA-directed DNA polymerase activity
JKL50_RS12435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JKL50_RS12440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JKL50_RS12445	COG0594	ribonuclease P activity
JKL50_RS12450	COG0706	membrane insertase activity
JKL50_RS12455	COG1847	R3H domain protein
JKL50_RS12460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JKL50_RS12465	COG0445	tRNA wobble uridine modification
JKL50_RS12470	COG0357	Ribosomal RNA small subunit methyltransferase G
JKL50_RS12475	COG1475	DNA binding
JKL50_RS12485	COG1192	Involved in chromosome partitioning
JKL50_RS12490	COG1475	DNA binding
JKL50_RS12500	COG3949	Membrane
JKL50_RS12515	COG4481	Protein conserved in bacteria
JKL50_RS12520	COG0012	GTP binding
JKL50_RS12525	COG0360	Binds together with S18 to 16S ribosomal RNA
JKL50_RS12530	COG0629	single-stranded DNA binding
JKL50_RS12535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JKL50_RS12540	COG0517	IMP dehydrogenase activity
JKL50_RS12540	COG1125	glycine betaine transport
JKL50_RS12545	COG1174	glycine betaine transport
JKL50_RS12550	COG0346	lactoylglutathione lyase activity
JKL50_RS12555	COG0400	carboxylic ester hydrolase activity
JKL50_RS12560	COG0655	NAD(P)H dehydrogenase (quinone) activity
JKL50_RS12565	COG0753	catalase activity
JKL50_RS12575	COG1595	DNA-templated transcription, initiation
JKL50_RS12585	COG1227	inorganic diphosphatase activity
JKL50_RS12590	COG4241	membrane
JKL50_RS12595	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JKL50_RS12600	COG0359	binds to the 23S rRNA
JKL50_RS12605	COG2807	transmembrane transport
JKL50_RS12610	COG3093	addiction module antidote protein HigA
JKL50_RS12615	COG2819	hydrolase of the alpha beta superfamily
JKL50_RS12620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS12625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS12625	COG2207	Transcriptional regulator
JKL50_RS12630	COG2819	hydrolase of the alpha beta superfamily
JKL50_RS12645	COG0305	Participates in initiation and elongation during chromosome replication
JKL50_RS12650	COG0346	lactoylglutathione lyase activity
JKL50_RS12655	COG2124	cytochrome p450
JKL50_RS12660	COG1309	transcriptional regulator
JKL50_RS12665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JKL50_RS12670	COG2311	Membrane
JKL50_RS12680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JKL50_RS12705	COG0745	RESPONSE REGULATOR receiver
JKL50_RS12710	COG5002	protein histidine kinase activity
JKL50_RS12715	COG4863	YycH protein
JKL50_RS12720	COG4853	Protein conserved in bacteria
JKL50_RS12725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JKL50_RS12730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKL50_RS12735	COG0456	acetyltransferase
JKL50_RS12755	COG4720	Psort location CytoplasmicMembrane, score
JKL50_RS12765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKL50_RS12775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JKL50_RS12790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS12805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JKL50_RS12825	COG0583	DNA-binding transcription factor activity
JKL50_RS12830	COG0384	phenazine biosynthesis protein PhzF
JKL50_RS12840	COG2188	Transcriptional regulator
JKL50_RS12850	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS12870	COG5444	nuclease activity
JKL50_RS12885	COG1263	PTS System
JKL50_RS12885	COG2190	(PTS) system
JKL50_RS12885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS12895	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS12900	COG2814	Major facilitator Superfamily
JKL50_RS12905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JKL50_RS12910	COG2814	Major facilitator Superfamily
JKL50_RS12915	COG1609	Transcriptional regulator
JKL50_RS12920	COG1113	amino acid transport
JKL50_RS12935	COG0494	nUDIX hydrolase
JKL50_RS12960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS12960	COG2190	(PTS) system
JKL50_RS12960	COG1263	PTS System
JKL50_RS12965	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS12970	COG3711	transcriptional antiterminator
JKL50_RS12975	COG0457	Tetratricopeptide repeat
JKL50_RS12980	COG1136	(ABC) transporter
JKL50_RS12990	COG2814	Major facilitator Superfamily
JKL50_RS12995	COG1309	transcriptional regulator
JKL50_RS13000	COG3835	regulator
JKL50_RS13005	COG2610	gluconate transmembrane transporter activity
JKL50_RS13010	COG1929	Belongs to the glycerate kinase type-1 family
JKL50_RS13015	COG2824	Alkylphosphonate utilization operon protein PhnA
JKL50_RS13020	COG1131	(ABC) transporter
JKL50_RS13025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JKL50_RS13035	COG2851	Citrate transporter
JKL50_RS13040	COG1874	Beta-galactosidase
JKL50_RS13050	COG3833	ABC-type maltose transport systems, permease component
JKL50_RS13055	COG1175	transmembrane transport
JKL50_RS13060	COG2182	Extracellular solute-binding protein
JKL50_RS13065	COG1609	Transcriptional regulator
JKL50_RS13070	COG0583	DNA-binding transcription factor activity
JKL50_RS13105	COG1737	Transcriptional regulator
JKL50_RS13110	COG1070	Carbohydrate kinase
JKL50_RS13120	COG4335	DNA alkylation repair
JKL50_RS13125	COG1113	amino acid transport
JKL50_RS13130	COG0840	transmembrane signaling receptor activity
JKL50_RS13135	COG0673	inositol 2-dehydrogenase activity
JKL50_RS13140	COG0789	Transcriptional regulator
JKL50_RS13145	COG0561	phosphatase activity
JKL50_RS13155	COG2226	methyltransferase
JKL50_RS13160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JKL50_RS13165	COG0477	Major facilitator Superfamily
JKL50_RS13170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JKL50_RS13170	COG2755	lipolytic protein G-D-S-L family
JKL50_RS13180	COG2390	Transcriptional regulator
JKL50_RS13185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JKL50_RS13190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JKL50_RS13195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JKL50_RS13200	COG1846	Transcriptional regulator
JKL50_RS13205	COG0778	Nitroreductase
JKL50_RS13210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JKL50_RS13245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JKL50_RS13250	COG4721	ABC-type cobalt transport system, permease component
JKL50_RS13255	COG1122	ATPase activity
JKL50_RS13260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JKL50_RS13270	COG3878	Protein conserved in bacteria
JKL50_RS13275	COG3711	transcriptional antiterminator
JKL50_RS13280	COG1263	PTS System
JKL50_RS13280	COG2190	(PTS) system
JKL50_RS13280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS13285	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS13310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JKL50_RS13315	COG2610	gluconate transmembrane transporter activity
JKL50_RS13325	COG2084	Dehydrogenase
JKL50_RS13330	COG1737	Transcriptional regulator
JKL50_RS13345	COG2195	Cleaves the N-terminal amino acid of tripeptides
JKL50_RS13350	COG4842	Belongs to the WXG100 family
JKL50_RS13375	COG1396	sequence-specific DNA binding
JKL50_RS13380	COG0252	asparaginase activity
JKL50_RS13385	COG1027	Aspartate ammonia-lyase
JKL50_RS13390	COG1757	Na H antiporter
JKL50_RS13415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS13415	COG3711	transcriptional antiterminator
JKL50_RS13420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS13425	COG1312	Catalyzes the dehydration of D-mannonate
JKL50_RS13430	COG2723	6-phospho-beta-galactosidase activity
JKL50_RS13435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS13440	COG1447	Phosphotransferase system cellobiose-specific component IIA
JKL50_RS13445	COG0726	polysaccharide deacetylase
JKL50_RS13455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKL50_RS13455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JKL50_RS13460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS13460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JKL50_RS13465	COG2514	catechol 2,3-dioxygenase activity
JKL50_RS13470	COG1733	regulation of RNA biosynthetic process
JKL50_RS13475	COG5386	Cell surface protein
JKL50_RS13480	COG5386	Cell surface protein
JKL50_RS13505	COG4509	Sortase family
JKL50_RS13510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JKL50_RS13515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS13520	COG1120	ATPase activity
JKL50_RS13525	COG1271	oxidase subunit
JKL50_RS13530	COG1294	oxidase, subunit
JKL50_RS13535	COG4988	ABC transporter
JKL50_RS13540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JKL50_RS13550	COG1595	DNA-templated transcription, initiation
JKL50_RS13565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JKL50_RS13580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS13580	COG3711	transcriptional antiterminator
JKL50_RS13585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS13590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JKL50_RS13595	COG1447	Phosphotransferase system cellobiose-specific component IIA
JKL50_RS13600	COG1486	melibiose metabolic process
JKL50_RS13610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JKL50_RS13615	COG3420	alginic acid biosynthetic process
JKL50_RS13625	COG1129	ABC transporter
JKL50_RS13630	COG1172	Belongs to the binding-protein-dependent transport system permease family
JKL50_RS13635	COG2357	RelA SpoT domain protein
JKL50_RS13645	COG0457	Tetratricopeptide repeat
JKL50_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS13655	COG0765	amino acid transport
JKL50_RS13665	COG0346	lactoylglutathione lyase activity
JKL50_RS13670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JKL50_RS13675	COG1346	cytolysis
JKL50_RS13680	COG1380	Effector of murein hydrolase LrgA
JKL50_RS13685	COG0583	DNA-binding transcription factor activity
JKL50_RS13690	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JKL50_RS13695	COG0352	thiamine-phosphate diphosphorylase activity
JKL50_RS13710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JKL50_RS13715	COG3162	membrane
JKL50_RS13725	COG0457	Tetratricopeptide repeat
JKL50_RS13750	COG2246	polysaccharide biosynthetic process
JKL50_RS13765	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JKL50_RS13770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JKL50_RS13775	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JKL50_RS13785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JKL50_RS13790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JKL50_RS13795	COG1845	cytochrome c oxidase, subunit III
JKL50_RS13800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JKL50_RS13810	COG0772	Belongs to the SEDS family
JKL50_RS13815	COG0778	Nitroreductase
JKL50_RS13820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS13830	COG1404	Belongs to the peptidase S8 family
JKL50_RS13840	COG3711	transcriptional antiterminator
JKL50_RS13845	COG1263	PTS System
JKL50_RS13845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JKL50_RS13850	COG1621	beta-fructofuranosidase activity
JKL50_RS13865	COG0351	phosphomethylpyrimidine kinase
JKL50_RS13875	COG1216	Glycosyl transferase, family 2
JKL50_RS13880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JKL50_RS13885	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS13895	COG2233	PERMEase
JKL50_RS13900	COG2363	Small membrane protein
JKL50_RS13920	COG0463	Glycosyl transferase, family 2
JKL50_RS13925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JKL50_RS13930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JKL50_RS13935	COG0456	acetyltransferase
JKL50_RS13940	COG2089	acid synthase
JKL50_RS13945	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JKL50_RS13950	COG3980	spore coat polysaccharide biosynthesis protein
JKL50_RS13955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JKL50_RS13960	COG1088	dTDP-glucose 4,6-dehydratase activity
JKL50_RS13965	COG1091	dTDP-4-dehydrorhamnose reductase activity
JKL50_RS13970	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JKL50_RS13975	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS13980	COG0436	Aminotransferase
JKL50_RS13985	COG0151	Belongs to the GarS family
JKL50_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS13995	COG1917	Cupin 2, conserved barrel domain protein
JKL50_RS14000	COG0077	Prephenate dehydratase
JKL50_RS14005	COG2814	Major facilitator Superfamily
JKL50_RS14010	COG1522	sequence-specific DNA binding
JKL50_RS14015	COG2814	Major facilitator Superfamily
JKL50_RS14025	COG0280	phosphate acetyltransferase
JKL50_RS14035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JKL50_RS14065	COG5444	nuclease activity
JKL50_RS14125	COG4844	belongs to the
JKL50_RS14130	COG1078	dGTPase activity
JKL50_RS14135	COG3465	dGTPase activity
JKL50_RS14140	COG1126	abc transporter atp-binding protein
JKL50_RS14145	COG0765	amino acid transport
JKL50_RS14155	COG0765	amino acid transport
JKL50_RS14160	COG0454	-acetyltransferase
JKL50_RS14165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JKL50_RS14170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS14175	COG0431	NADPH-dependent FMN reductase
JKL50_RS14180	COG0583	DNA-binding transcription factor activity
JKL50_RS14185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JKL50_RS14195	COG1942	4-Oxalocrotonate Tautomerase
JKL50_RS14200	COG1994	Peptidase M50
JKL50_RS14210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JKL50_RS14215	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JKL50_RS14220	COG0010	Belongs to the arginase family
JKL50_RS14230	COG4506	Protein conserved in bacteria
JKL50_RS14235	COG0018	arginyl-trna synthetase
JKL50_RS14240	COG1619	proteins homologs of microcin C7 resistance protein MccF
JKL50_RS14245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKL50_RS14250	COG1132	(ABC) transporter
JKL50_RS14260	COG1619	proteins homologs of microcin C7 resistance protein MccF
JKL50_RS14270	COG4294	response to UV
JKL50_RS14275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JKL50_RS14280	COG2181	nitrate reductase activity
JKL50_RS14280	COG0247	lactate metabolic process
JKL50_RS14285	COG0183	Belongs to the thiolase family
JKL50_RS14290	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKL50_RS14295	COG1960	acyl-CoA dehydrogenase activity
JKL50_RS14300	COG1960	acyl-CoA dehydrogenase activity
JKL50_RS14315	COG3343	RNA polymerase activity
JKL50_RS14320	COG0504	CTP synthase activity
JKL50_RS14325	COG4821	SIS domain
JKL50_RS14330	COG2204	response regulator
JKL50_RS14335	COG0191	fructose-bisphosphate aldolase activity
JKL50_RS14340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JKL50_RS14345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JKL50_RS14350	COG1494	fructose-1,6-bisphosphatase
JKL50_RS14355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JKL50_RS14360	COG0254	rRNA binding
JKL50_RS14365	COG1435	thymidine kinase activity
JKL50_RS14370	COG0281	malic enzyme
JKL50_RS14375	COG0679	Auxin Efflux Carrier
JKL50_RS14380	COG0789	Transcriptional regulator
JKL50_RS14385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JKL50_RS14390	COG2890	protein-(glutamine-N5) methyltransferase activity
JKL50_RS14405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JKL50_RS14410	COG0009	L-threonylcarbamoyladenylate synthase
JKL50_RS14415	COG1971	Probably functions as a manganese efflux pump
JKL50_RS14420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JKL50_RS14425	COG0698	ribose 5-phosphate isomerase
JKL50_RS14430	COG4475	Protein of unknown function (DUF436)
JKL50_RS14435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JKL50_RS14440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JKL50_RS14450	COG0356	it plays a direct role in the translocation of protons across the membrane
JKL50_RS14455	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKL50_RS14460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JKL50_RS14465	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JKL50_RS14470	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JKL50_RS14475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JKL50_RS14480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JKL50_RS14485	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JKL50_RS14495	COG4836	Membrane
JKL50_RS14505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JKL50_RS14510	COG2385	sporulation resulting in formation of a cellular spore
JKL50_RS14515	COG2304	oxidoreductase activity
JKL50_RS14520	COG2304	oxidoreductase activity
JKL50_RS14530	COG2223	nitrite transmembrane transporter activity
JKL50_RS14535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JKL50_RS14540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JKL50_RS14545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JKL50_RS14550	COG0523	cobalamin synthesis protein
JKL50_RS14555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JKL50_RS14590	COG1247	-acetyltransferase
JKL50_RS14595	COG0739	heme binding
JKL50_RS14600	COG0347	Belongs to the P(II) protein family
JKL50_RS14605	COG0004	ammonium transporteR
JKL50_RS14610	COG1126	abc transporter atp-binding protein
JKL50_RS14615	COG0765	amino acid transport
JKL50_RS14620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS14625	COG0477	Major facilitator Superfamily
JKL50_RS14630	COG0671	phosphoesterase, PA-phosphatase related
JKL50_RS14635	COG2814	Major facilitator Superfamily
JKL50_RS14640	COG1846	Transcriptional regulator
JKL50_RS14645	COG1609	Transcriptional regulator
JKL50_RS14650	COG1077	Cell shape determining protein MreB Mrl
JKL50_RS14655	COG4786	Flagellar basal body rod
JKL50_RS14660	COG4786	Flagellar basal body rod
JKL50_RS14665	COG0457	Tetratricopeptide repeat
JKL50_RS14670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JKL50_RS14675	COG1970	mechanosensitive ion channel activity
JKL50_RS14690	COG0561	phosphatase activity
JKL50_RS14695	COG2202	Pas domain
JKL50_RS14695	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS14700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JKL50_RS14705	COG4715	Zinc finger, swim domain protein
JKL50_RS14715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JKL50_RS14720	COG2059	Chromate
JKL50_RS14725	COG2059	Chromate
JKL50_RS14730	COG1522	sequence-specific DNA binding
JKL50_RS14735	COG3527	Alpha-acetolactate decarboxylase
JKL50_RS14740	COG0028	Belongs to the TPP enzyme family
JKL50_RS14745	COG0583	DNA-binding transcription factor activity
JKL50_RS14750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JKL50_RS14755	COG1879	ABC-type sugar transport system periplasmic component
JKL50_RS14760	COG1172	Belongs to the binding-protein-dependent transport system permease family
JKL50_RS14765	COG1129	ABC transporter
JKL50_RS14770	COG1869	D-ribose catabolic process
JKL50_RS14775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JKL50_RS14780	COG1609	Transcriptional regulator
JKL50_RS14795	COG0697	spore germination
JKL50_RS14800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JKL50_RS14810	COG2843	Capsule synthesis protein
JKL50_RS14820	COG0791	NLP P60 protein
JKL50_RS14825	COG0561	phosphatase activity
JKL50_RS14830	COG1316	TRANSCRIPTIONal
JKL50_RS14835	COG2814	Major facilitator Superfamily
JKL50_RS14850	COG0814	amino acid
JKL50_RS14855	COG0697	spore germination
JKL50_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS14865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JKL50_RS14870	COG1609	Transcriptional regulator
JKL50_RS14875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JKL50_RS14880	COG0800	Aldolase
JKL50_RS14885	COG0454	-acetyltransferase
JKL50_RS14895	COG2972	Histidine kinase
JKL50_RS14900	COG2197	response regulator
JKL50_RS14905	COG1653	transport
JKL50_RS14910	COG1175	transmembrane transport
JKL50_RS14920	COG1482	cell wall glycoprotein biosynthetic process
JKL50_RS14925	COG4193	domain, Protein
JKL50_RS14930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JKL50_RS14935	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JKL50_RS14940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JKL50_RS14950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JKL50_RS14955	COG0463	Glycosyl transferase, family 2
JKL50_RS14955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JKL50_RS14960	COG1682	transport, permease protein
JKL50_RS14965	COG1134	teichoic acid transport
JKL50_RS14970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JKL50_RS14975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JKL50_RS14985	COG1316	TRANSCRIPTIONal
JKL50_RS14995	COG2385	sporulation resulting in formation of a cellular spore
JKL50_RS14995	COG2247	cell wall binding repeat
JKL50_RS15000	COG2247	cell wall binding repeat
JKL50_RS15000	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS15005	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS15005	COG2247	cell wall binding repeat
JKL50_RS15020	COG2244	polysaccharide biosynthetic process
JKL50_RS15025	COG0438	transferase activity, transferring glycosyl groups
JKL50_RS15025	COG0297	glycogen (starch) synthase activity
JKL50_RS15030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JKL50_RS15035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKL50_RS15040	COG3307	-O-antigen
JKL50_RS15045	COG3206	protein involved in exopolysaccharide biosynthesis
JKL50_RS15050	COG1215	transferase activity, transferring glycosyl groups
JKL50_RS15055	COG0438	transferase activity, transferring glycosyl groups
JKL50_RS15060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JKL50_RS15065	COG1316	TRANSCRIPTIONal
JKL50_RS15070	COG1739	Uncharacterized protein family UPF0029
JKL50_RS15075	COG4585	Histidine kinase
JKL50_RS15080	COG2197	response regulator
JKL50_RS15085	COG1307	EDD domain protein, DegV family
JKL50_RS15090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JKL50_RS15100	COG1040	competence protein
JKL50_RS15115	COG3418	PFAM FlgN family protein
JKL50_RS15120	COG4786	Flagellar basal body rod
JKL50_RS15120	COG1256	bacterial-type flagellum assembly
JKL50_RS15125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JKL50_RS15135	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JKL50_RS15140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JKL50_RS15145	COG1334	flagellar protein FlaG
JKL50_RS15150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JKL50_RS15155	COG1516	flagellar protein fliS
JKL50_RS15170	COG0840	transmembrane signaling receptor activity
JKL50_RS15175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JKL50_RS15180	COG0653	protein targeting
JKL50_RS15200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JKL50_RS15205	COG2010	Cytochrome c
JKL50_RS15210	COG2884	Cell division ATP-binding protein ftsE
JKL50_RS15215	COG2177	Part of the ABC transporter FtsEX involved in
JKL50_RS15220	COG3883	PFAM NLP P60 protein
JKL50_RS15220	COG0791	NLP P60 protein
JKL50_RS15225	COG0730	response to heat
JKL50_RS15230	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS15230	COG0793	Belongs to the peptidase S41A family
JKL50_RS15240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKL50_RS15245	COG1733	regulation of RNA biosynthetic process
JKL50_RS15250	COG0778	Nitroreductase
JKL50_RS15255	COG1113	amino acid transport
JKL50_RS15260	COG0463	Glycosyl transferase, family 2
JKL50_RS15265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JKL50_RS15270	COG5002	protein histidine kinase activity
JKL50_RS15275	COG0745	RESPONSE REGULATOR receiver
JKL50_RS15285	COG2814	Major facilitator Superfamily
JKL50_RS15290	COG1309	transcriptional regulator
JKL50_RS15295	COG0574	Belongs to the PEP-utilizing enzyme family
JKL50_RS15295	COG3848	Pyruvate phosphate dikinase
JKL50_RS15300	COG4897	Protein conserved in bacteria
JKL50_RS15310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JKL50_RS15325	COG3595	metallopeptidase activity
JKL50_RS15330	COG1983	PspC domain protein
JKL50_RS15335	COG1950	PFAM Membrane protein of
JKL50_RS15340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JKL50_RS15345	COG2188	Transcriptional regulator
JKL50_RS15350	COG0363	glucosamine-6-phosphate deaminase activity
JKL50_RS15355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JKL50_RS15360	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JKL50_RS15370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JKL50_RS15375	COG0546	phosphoglycolate phosphatase activity
JKL50_RS15380	COG0110	maltose O-acetyltransferase activity
JKL50_RS15385	COG1959	2 iron, 2 sulfur cluster binding
JKL50_RS15390	COG2910	NAD(P)H-binding
JKL50_RS15410	COG4990	cell redox homeostasis
JKL50_RS15415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JKL50_RS15420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JKL50_RS15425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JKL50_RS15430	COG0131	Imidazoleglycerol-phosphate dehydratase
JKL50_RS15435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JKL50_RS15440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JKL50_RS15445	COG0107	imidazoleglycerol-phosphate synthase activity
JKL50_RS15450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JKL50_RS15450	COG0140	phosphoribosyl-ATP diphosphatase activity
JKL50_RS15455	COG0457	Tetratricopeptide repeat
JKL50_RS15460	COG3883	PFAM NLP P60 protein
JKL50_RS15460	COG0791	NLP P60 protein
JKL50_RS15465	COG0492	ferredoxin-NADP+ reductase activity
JKL50_RS15470	COG1051	belongs to the nudix hydrolase family
JKL50_RS15475	COG1660	Displays ATPase and GTPase activities
JKL50_RS15480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JKL50_RS15485	COG1481	regulation of sporulation
JKL50_RS15490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JKL50_RS15495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JKL50_RS15505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JKL50_RS15510	COG0288	reversible hydration of carbon dioxide
JKL50_RS15515	COG0659	secondary active sulfate transmembrane transporter activity
JKL50_RS15520	COG1694	Mazg nucleotide pyrophosphohydrolase
JKL50_RS15525	COG1611	Belongs to the LOG family
JKL50_RS15530	COG0740	serine-type endopeptidase activity
JKL50_RS15545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS15550	COG1819	glycosyl
JKL50_RS15555	COG0747	negative chemotaxis
JKL50_RS15560	COG0601	transmembrane transport
JKL50_RS15580	COG0488	(ABC) transporter
JKL50_RS15585	COG0726	polysaccharide deacetylase
JKL50_RS15590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS15595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS15600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS15610	COG1396	sequence-specific DNA binding
JKL50_RS15615	COG3944	biosynthesis protein
JKL50_RS15620	COG0489	protein tyrosine kinase activity
JKL50_RS15625	COG1086	Polysaccharide biosynthesis protein
JKL50_RS15630	COG0438	transferase activity, transferring glycosyl groups
JKL50_RS15635	COG1215	transferase activity, transferring glycosyl groups
JKL50_RS15640	COG0438	transferase activity, transferring glycosyl groups
JKL50_RS15650	COG1216	Glycosyl transferase, family 2
JKL50_RS15655	COG5039	Polysaccharide pyruvyl transferase
JKL50_RS15660	COG2244	polysaccharide biosynthetic process
JKL50_RS15665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JKL50_RS15670	COG0110	maltose O-acetyltransferase activity
JKL50_RS15675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JKL50_RS15680	COG0747	negative chemotaxis
JKL50_RS15685	COG0601	transmembrane transport
JKL50_RS15690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JKL50_RS15695	COG0444	Belongs to the ABC transporter superfamily
JKL50_RS15700	COG4608	Belongs to the ABC transporter superfamily
JKL50_RS15705	COG0534	Mate efflux family protein
JKL50_RS15715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JKL50_RS15720	COG2186	Transcriptional regulator
JKL50_RS15725	COG3829	transcription factor binding
JKL50_RS15730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JKL50_RS15735	COG0833	amino acid
JKL50_RS15740	COG2390	Transcriptional regulator
JKL50_RS15745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JKL50_RS15750	COG0126	phosphoglycerate kinase activity
JKL50_RS15755	COG0149	triose-phosphate isomerase activity
JKL50_RS15760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JKL50_RS15765	COG0148	phosphopyruvate hydratase activity
JKL50_RS15775	COG1131	(ABC) transporter
JKL50_RS15795	COG0456	acetyltransferase
JKL50_RS15805	COG2095	MarC family integral membrane protein
JKL50_RS15810	COG1510	regulation of RNA biosynthetic process
JKL50_RS15815	COG1125	glycine betaine transport
JKL50_RS15815	COG0517	IMP dehydrogenase activity
JKL50_RS15820	COG1174	glycine betaine transport
JKL50_RS15825	COG1732	Glycine betaine
JKL50_RS15830	COG1174	glycine betaine transport
JKL50_RS15835	COG1733	regulation of RNA biosynthetic process
JKL50_RS15840	COG1396	sequence-specific DNA binding
JKL50_RS15845	COG1396	sequence-specific DNA binding
JKL50_RS15850	COG1476	TRANSCRIPTIONal
JKL50_RS15855	COG2002	toxin-antitoxin pair type II binding
JKL50_RS15860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JKL50_RS15865	COG1647	Serine aminopeptidase, S33
JKL50_RS15870	COG0557	exoribonuclease II activity
JKL50_RS15875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JKL50_RS15910	COG1937	Protein conserved in bacteria
JKL50_RS15915	COG2608	mercury ion transmembrane transporter activity
JKL50_RS15920	COG2217	Heavy metal translocating P-type atpase
JKL50_RS15935	COG1027	Aspartate ammonia-lyase
JKL50_RS15940	COG4191	Histidine kinase
JKL50_RS15945	COG0784	Response regulator, receiver
JKL50_RS15950	COG3226	Transcriptional regulator
JKL50_RS15960	COG0803	Belongs to the bacterial solute-binding protein 9 family
JKL50_RS15965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JKL50_RS15970	COG1121	(ABC) transporter
JKL50_RS15975	COG2217	Heavy metal translocating P-type atpase
JKL50_RS15980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JKL50_RS15985	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JKL50_RS15990	COG2860	membrane
JKL50_RS15995	COG0025	NhaP-type Na H and K H
JKL50_RS16000	COG1940	carbohydrate kinase activity
JKL50_RS16005	COG0656	L-ascorbic acid biosynthetic process
JKL50_RS16010	COG4149	molybdate abc transporter
JKL50_RS16015	COG0725	ABC transporter, periplasmic molybdate-binding protein
JKL50_RS16020	COG1368	sulfuric ester hydrolase activity
JKL50_RS16025	COG1988	membrane-bound metal-dependent
JKL50_RS16040	COG0531	amino acid
JKL50_RS16045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS16050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS16055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS16060	COG1120	ATPase activity
JKL50_RS16065	COG0745	RESPONSE REGULATOR receiver
JKL50_RS16070	COG2205	protein histidine kinase activity
JKL50_RS16075	COG1904	glucuronate isomerase
JKL50_RS16080	COG1609	Transcriptional regulator
JKL50_RS16085	COG0246	Mannitol dehydrogenase
JKL50_RS16090	COG2721	sulfolactate sulfo-lyase activity
JKL50_RS16100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS16110	COG1120	ATPase activity
JKL50_RS16115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JKL50_RS16120	COG1454	alcohol dehydrogenase
JKL50_RS16135	COG3604	Transcriptional regulator
JKL50_RS16145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JKL50_RS16150	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS16155	COG2096	Adenosyltransferase
JKL50_RS16160	COG4758	membrane
JKL50_RS16165	COG1842	Phage shock protein A
JKL50_RS16175	COG4758	membrane
JKL50_RS16180	COG4585	Histidine kinase
JKL50_RS16185	COG2197	response regulator
JKL50_RS16200	COG0814	amino acid
JKL50_RS16205	COG0697	spore germination
JKL50_RS16215	COG0114	fumarate hydratase activity
JKL50_RS16225	COG1309	transcriptional regulator
JKL50_RS16235	COG2770	Histidine kinase
JKL50_RS16235	COG2205	protein histidine kinase activity
JKL50_RS16240	COG0745	RESPONSE REGULATOR receiver
JKL50_RS16245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JKL50_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS16260	COG1120	ATPase activity
JKL50_RS16270	COG5577	PFAM Coat F domain
JKL50_RS16285	COG1024	Enoyl-CoA hydratase
JKL50_RS16285	COG1250	3-hydroxyacyl-CoA dehydrogenase
JKL50_RS16290	COG0183	Belongs to the thiolase family
JKL50_RS16295	COG1960	acyl-CoA dehydrogenase activity
JKL50_RS16300	COG1393	Belongs to the ArsC family
JKL50_RS16305	COG0509	glycine decarboxylation via glycine cleavage system
JKL50_RS16315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JKL50_RS16320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS16330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JKL50_RS16335	COG2011	ABC-type metal ion transport system permease component
JKL50_RS16340	COG1464	Belongs to the NlpA lipoprotein family
JKL50_RS16345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JKL50_RS16355	COG0396	ATPase activity
JKL50_RS16360	COG0719	Fe-S assembly protein
JKL50_RS16365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JKL50_RS16370	COG0822	iron-sulfur transferase activity
JKL50_RS16375	COG0719	Fe-S assembly protein
JKL50_RS16395	COG1309	transcriptional regulator
JKL50_RS16405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JKL50_RS16415	COG2311	Membrane
JKL50_RS16420	COG0745	RESPONSE REGULATOR receiver
JKL50_RS16425	COG5002	protein histidine kinase activity
JKL50_RS16425	COG0642	Histidine kinase
JKL50_RS16435	COG0561	phosphatase activity
JKL50_RS16450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS16455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS16460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JKL50_RS16475	COG2356	endonuclease I
JKL50_RS16480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JKL50_RS16485	COG2814	Major facilitator Superfamily
JKL50_RS16490	COG2140	Oxalate decarboxylase
JKL50_RS16495	COG2508	Transcriptional regulator
JKL50_RS16500	COG1801	Protein of unknown function DUF72
JKL50_RS16505	COG0737	Belongs to the 5'-nucleotidase family
JKL50_RS16510	COG3377	Domain of unknown function (DUF1805)
JKL50_RS16530	COG0739	heme binding
JKL50_RS16535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JKL50_RS16545	COG4470	Protein conserved in bacteria
JKL50_RS16550	COG2445	Protein of unknown function DUF86
JKL50_RS16555	COG0647	UMP catabolic process
JKL50_RS16560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JKL50_RS16565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JKL50_RS16570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JKL50_RS16575	COG0460	homoserine dehydrogenase
JKL50_RS16580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JKL50_RS16585	COG0083	homoserine kinase activity
JKL50_RS16590	COG0823	Involved in the tonB-independent uptake of proteins
JKL50_RS16590	COG4946	Tricorn protease homolog
JKL50_RS16590	COG1506	peptidase
JKL50_RS16595	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JKL50_RS16600	COG4837	Protein of unknown function (DUF1462)
JKL50_RS16610	COG1252	NADH dehydrogenase
JKL50_RS16615	COG4844	belongs to the
JKL50_RS16620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JKL50_RS16625	COG0316	Belongs to the HesB IscA family
JKL50_RS16630	COG5504	Zn-dependent protease
JKL50_RS16635	COG0789	Transcriptional regulator
JKL50_RS16650	COG0492	ferredoxin-NADP+ reductase activity
JKL50_RS16655	COG1252	NADH dehydrogenase
JKL50_RS16670	COG3584	3D domain protein
JKL50_RS16675	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JKL50_RS16680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JKL50_RS16685	COG2056	Na+-H+ antiporter family
JKL50_RS16690	COG1268	BioY protein
JKL50_RS16695	COG0686	Belongs to the AlaDH PNT family
JKL50_RS16700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JKL50_RS16700	COG2508	Transcriptional regulator
JKL50_RS16705	COG4842	Belongs to the WXG100 family
JKL50_RS16710	COG5417	Belongs to the EsaB family
JKL50_RS16715	COG4499	WXG100 protein secretion system (Wss), protein YukC
JKL50_RS16720	COG1674	ftsk spoiiie
JKL50_RS16720	COG0433	COG0433 Predicted ATPase
JKL50_RS16725	COG1511	domain protein
JKL50_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS16740	COG1418	mRNA catabolic process
JKL50_RS16755	COG0628	permease
JKL50_RS16775	COG5506	Protein of unknown function (DUF1694)
JKL50_RS16780	COG1335	isochorismatase
JKL50_RS16785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JKL50_RS16790	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JKL50_RS16805	COG0142	geranyltranstransferase activity
JKL50_RS16815	COG4585	Histidine kinase
JKL50_RS16820	COG2197	response regulator
JKL50_RS16825	COG2050	protein possibly involved in aromatic compounds catabolism
JKL50_RS16830	COG1320	monovalent cation:proton antiporter activity
JKL50_RS16835	COG2212	antiporter activity
JKL50_RS16840	COG1863	multisubunit Na H antiporter MnhE subunit
JKL50_RS16845	COG0651	ATP synthesis coupled electron transport
JKL50_RS16850	COG1006	Multisubunit Na H antiporter MnhC subunit
JKL50_RS16855	COG2111	Na H antiporter
JKL50_RS16860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JKL50_RS16860	COG2111	Na H antiporter
JKL50_RS16870	COG3493	citrate carrier protein
JKL50_RS16875	COG1079	Belongs to the binding-protein-dependent transport system permease family
JKL50_RS16880	COG4603	Belongs to the binding-protein-dependent transport system permease family
JKL50_RS16885	COG3845	ABC transporter
JKL50_RS16890	COG1744	ABC transporter substrate-binding protein PnrA-like
JKL50_RS16895	COG4565	transcriptional regulatory protein
JKL50_RS16900	COG3290	protein histidine kinase activity
JKL50_RS16910	COG3011	Protein conserved in bacteria
JKL50_RS16915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JKL50_RS16920	COG2814	Major facilitator Superfamily
JKL50_RS16925	COG5018	Exonuclease
JKL50_RS16940	COG2205	protein histidine kinase activity
JKL50_RS16945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JKL50_RS16955	COG2267	carboxylic ester hydrolase activity
JKL50_RS16960	COG1522	sequence-specific DNA binding
JKL50_RS16965	COG0436	Aminotransferase
JKL50_RS16970	COG1098	S1 RNA binding domain
JKL50_RS16975	COG2155	Conserved Protein
JKL50_RS16980	COG1979	alcohol dehydrogenase
JKL50_RS16985	COG1979	alcohol dehydrogenase
JKL50_RS16990	COG0166	Belongs to the GPI family
JKL50_RS17005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JKL50_RS17015	COG2738	Putative neutral zinc metallopeptidase
JKL50_RS17020	COG1253	flavin adenine dinucleotide binding
JKL50_RS17025	COG0432	Pfam Uncharacterised protein family UPF0047
JKL50_RS17030	COG2070	2-Nitropropane dioxygenase
JKL50_RS17045	COG0840	transmembrane signaling receptor activity
JKL50_RS17050	COG0840	transmembrane signaling receptor activity
JKL50_RS17055	COG0840	transmembrane signaling receptor activity
JKL50_RS17060	COG0840	transmembrane signaling receptor activity
JKL50_RS17065	COG0693	protein deglycase activity
JKL50_RS17070	COG0673	inositol 2-dehydrogenase activity
JKL50_RS17080	COG0628	permease
JKL50_RS17095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JKL50_RS17105	COG1396	sequence-specific DNA binding
JKL50_RS17125	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JKL50_RS17135	COG1595	DNA-templated transcription, initiation
JKL50_RS17140	COG5484	DNA packaging
JKL50_RS17145	COG1783	phage Terminase large subunit
JKL50_RS17150	COG5518	Phage portal protein
JKL50_RS17155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JKL50_RS17160	COG4653	Phage capsid family
JKL50_RS17215	COG5280	Phage tail tape measure protein TP901
JKL50_RS17215	COG3953	SLT domain
JKL50_RS17215	COG5280	Phage tail tape measure protein TP901
JKL50_RS17215	COG3953	SLT domain
JKL50_RS17220	COG1652	LysM domain
JKL50_RS17225	COG4193	domain, Protein
JKL50_RS17235	COG3628	GPW Gp25 family protein
JKL50_RS17240	COG3299	homolog of phage Mu protein gp47
JKL50_RS17245	COG3778	Protein conserved in bacteria
JKL50_RS17300	COG3409	Peptidoglycan-binding domain 1 protein
JKL50_RS17300	COG5632	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS17315	COG1510	regulation of RNA biosynthetic process
JKL50_RS17320	COG1012	belongs to the aldehyde dehydrogenase family
JKL50_RS17325	COG1454	alcohol dehydrogenase
JKL50_RS17330	COG2318	DinB family
JKL50_RS17335	COG1585	Membrane protein implicated in regulation of membrane protease activity
JKL50_RS17340	COG2268	Band 7 protein
JKL50_RS17345	COG0772	Belongs to the SEDS family
JKL50_RS17350	COG0772	Belongs to the SEDS family
JKL50_RS17355	COG3339	Conserved Protein
JKL50_RS17360	COG1247	-acetyltransferase
JKL50_RS17365	COG3859	Proton-coupled thiamine transporter YuaJ
JKL50_RS17495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JKL50_RS17500	COG1575	Belongs to the MenA family. Type 1 subfamily
JKL50_RS17505	COG1169	isochorismate synthase
JKL50_RS17510	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JKL50_RS17515	COG0596	Alpha beta hydrolase
JKL50_RS17520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JKL50_RS17525	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS17530	COG4948	Mandelate Racemase Muconate Lactonizing
JKL50_RS17545	COG1294	oxidase, subunit
JKL50_RS17550	COG1271	oxidase subunit
JKL50_RS17560	COG0803	Belongs to the bacterial solute-binding protein 9 family
JKL50_RS17560	COG3443	Belongs to the bacterial solute-binding protein 9 family
JKL50_RS17565	COG0288	reversible hydration of carbon dioxide
JKL50_RS17570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JKL50_RS17575	COG1854	S-ribosylhomocysteine lyase activity
JKL50_RS17590	COG0783	Belongs to the Dps family
JKL50_RS17600	COG4824	toxin secretion phage lysis holin
JKL50_RS17615	COG2310	stress, protein
JKL50_RS17620	COG0494	nUDIX hydrolase
JKL50_RS17625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JKL50_RS17630	COG1116	anion transmembrane transporter activity
JKL50_RS17635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JKL50_RS17655	COG1233	COG1233 Phytoene dehydrogenase and related
JKL50_RS17660	COG1506	peptidase
JKL50_RS17670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JKL50_RS17675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JKL50_RS17680	COG0367	asparagine synthase
JKL50_RS17685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JKL50_RS17690	COG2267	carboxylic ester hydrolase activity
JKL50_RS17700	COG4326	sporulation control protein
JKL50_RS17705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JKL50_RS17710	COG1242	4 iron, 4 sulfur cluster binding
JKL50_RS17730	COG1725	Transcriptional regulator
JKL50_RS17735	COG1131	(ABC) transporter
JKL50_RS17745	COG1136	(ABC) transporter
JKL50_RS17750	COG0577	efflux transmembrane transporter activity
JKL50_RS17755	COG2433	Pfam Transposase IS66
JKL50_RS17760	COG2202	Pas domain
JKL50_RS17760	COG1366	Belongs to the anti-sigma-factor antagonist family
JKL50_RS17770	COG0495	leucyl-tRNA aminoacylation
JKL50_RS17775	COG1073	alpha beta
JKL50_RS17780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JKL50_RS17785	COG0395	ABC-type sugar transport system, permease component
JKL50_RS17790	COG1653	transport
JKL50_RS17795	COG0656	L-ascorbic acid biosynthetic process
JKL50_RS17800	COG2814	Major facilitator Superfamily
JKL50_RS17805	COG1733	regulation of RNA biosynthetic process
JKL50_RS17810	COG2207	Transcriptional regulator
JKL50_RS17815	COG4209	transmembrane transport
JKL50_RS17820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JKL50_RS17825	COG1653	transport
JKL50_RS17830	COG0673	inositol 2-dehydrogenase activity
JKL50_RS17835	COG5578	integral membrane protein
JKL50_RS17840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JKL50_RS17850	COG3196	Protein conserved in bacteria
JKL50_RS17855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JKL50_RS17865	COG2081	HI0933 family
JKL50_RS17870	COG2244	polysaccharide biosynthetic process
JKL50_RS17875	COG1187	pseudouridine synthase activity
JKL50_RS17880	COG1349	DNA-binding transcription factor activity
JKL50_RS17885	COG2252	PERMEase
JKL50_RS17890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JKL50_RS17895	COG3340	Belongs to the peptidase S51 family
JKL50_RS17900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JKL50_RS17905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JKL50_RS17915	COG1597	lipid kinase activity
JKL50_RS17920	COG0510	thiamine kinase activity
JKL50_RS17930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JKL50_RS17935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JKL50_RS17940	COG0281	malic enzyme
JKL50_RS17945	COG5584	Small secreted protein
JKL50_RS17950	COG1363	Peptidase, m42
JKL50_RS17965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JKL50_RS17970	COG4848	Belongs to the UPF0354 family
JKL50_RS17975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKL50_RS17980	COG1674	ftsk spoiiie
JKL50_RS17985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JKL50_RS17990	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JKL50_RS17995	COG4980	gas vesicle protein
JKL50_RS18000	COG3118	belongs to the thioredoxin family
JKL50_RS18005	COG1605	Chorismate mutase
JKL50_RS18005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JKL50_RS18010	COG1609	Transcriptional regulator
JKL50_RS18015	COG0123	including yeast histone deacetylase and acetoin utilization protein
JKL50_RS18020	COG0517	IMP dehydrogenase activity
JKL50_RS18025	COG0454	-acetyltransferase
JKL50_RS18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKL50_RS18035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JKL50_RS18040	COG2329	Antibiotic biosynthesis monooxygenase
JKL50_RS18045	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JKL50_RS18065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JKL50_RS18070	COG1956	GAF domain-containing protein
JKL50_RS18075	COG1309	transcriptional regulator
JKL50_RS18080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JKL50_RS18085	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JKL50_RS18090	COG1114	Component of the transport system for branched-chain amino acids
JKL50_RS18095	COG1114	Component of the transport system for branched-chain amino acids
JKL50_RS18100	COG1104	cysteine desulfurase activity
JKL50_RS18105	COG0301	tRNA thio-modification
JKL50_RS18115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JKL50_RS18120	COG1279	arginine transmembrane transporter activity
JKL50_RS18135	COG2249	NAD(P)H dehydrogenase (quinone) activity
JKL50_RS18140	COG0402	S-adenosylhomocysteine deaminase activity
JKL50_RS18145	COG0577	efflux transmembrane transporter activity
JKL50_RS18150	COG1136	(ABC) transporter
JKL50_RS18155	COG2205	protein histidine kinase activity
JKL50_RS18160	COG0745	RESPONSE REGULATOR receiver
JKL50_RS18165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JKL50_RS18170	COG2197	response regulator
JKL50_RS18175	COG4585	Histidine kinase
JKL50_RS18180	COG3239	Fatty acid desaturase
JKL50_RS18190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JKL50_RS18195	COG0616	signal peptide processing
JKL50_RS18200	COG1714	RDD family
JKL50_RS18210	COG3874	Sporulation protein YtfJ
JKL50_RS18215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JKL50_RS18220	COG0827	DNA restriction-modification system
JKL50_RS18225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JKL50_RS18230	COG0521	Mo-molybdopterin cofactor biosynthetic process
JKL50_RS18235	COG0137	argininosuccinate synthase activity
JKL50_RS18240	COG0165	Argininosuccinate lyase
JKL50_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
JKL50_RS18255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JKL50_RS18260	COG4109	DRTGG domain
JKL50_RS18270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JKL50_RS18290	COG0587	DNA-directed DNA polymerase activity
JKL50_RS18295	COG0281	malic enzyme
JKL50_RS18300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JKL50_RS18305	COG0825	malonyl-CoA metabolic process
JKL50_RS18310	COG0205	6-phosphofructokinase activity
JKL50_RS18320	COG3030	protein affecting phage T7 exclusion by the F plasmid
JKL50_RS18325	COG0628	permease
JKL50_RS18330	COG2707	UPF0756 membrane protein
JKL50_RS18335	COG0372	Belongs to the citrate synthase family
JKL50_RS18340	COG0538	isocitrate dehydrogenase activity
JKL50_RS18345	COG0039	L-malate dehydrogenase activity
JKL50_RS18350	COG0745	RESPONSE REGULATOR receiver
JKL50_RS18355	COG5002	protein histidine kinase activity
JKL50_RS18360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKL50_RS18360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JKL50_RS18365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JKL50_RS18370	COG1971	Probably functions as a manganese efflux pump
JKL50_RS18375	COG0237	dephospho-CoA kinase activity
JKL50_RS18380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JKL50_RS18385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JKL50_RS18395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JKL50_RS18400	COG3611	Membrane attachment protein
JKL50_RS18405	COG1484	DNA-dependent DNA replication
JKL50_RS18410	COG0398	Pfam SNARE associated Golgi protein
JKL50_RS18420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JKL50_RS18430	COG1011	Hydrolase
JKL50_RS18440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JKL50_RS18445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JKL50_RS18450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JKL50_RS18455	COG3326	Membrane
JKL50_RS18465	COG1363	Peptidase, m42
JKL50_RS18470	COG1966	Carbon starvation protein
JKL50_RS18480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JKL50_RS18485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JKL50_RS18490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JKL50_RS18490	COG0072	phenylalanine-tRNA ligase activity
JKL50_RS18495	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JKL50_RS18500	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JKL50_RS18505	COG1286	toxin biosynthetic process
JKL50_RS18510	COG1796	DNA polymerase
JKL50_RS18510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JKL50_RS18515	COG1193	negative regulation of DNA recombination
JKL50_RS18520	COG3766	membrane
JKL50_RS18530	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS18535	COG1309	transcriptional regulator
JKL50_RS18540	COG1024	Enoyl-CoA hydratase
JKL50_RS18545	COG2086	electron transfer activity
JKL50_RS18550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JKL50_RS18555	COG3534	alpha-L-arabinofuranosidase
JKL50_RS18560	COG3118	belongs to the thioredoxin family
JKL50_RS18565	COG0322	excinuclease ABC activity
JKL50_RS18570	COG0527	aspartate kinase activity
JKL50_RS18575	COG1719	4-vinyl reductase, 4VR
JKL50_RS18580	COG2009	succinate dehydrogenase
JKL50_RS18585	COG1053	succinate dehydrogenase
JKL50_RS18590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JKL50_RS18595	COG0824	Thioesterase
JKL50_RS18605	COG2828	Protein conserved in bacteria
JKL50_RS18610	COG0583	DNA-binding transcription factor activity
JKL50_RS18615	COG2851	Citrate transporter
JKL50_RS18620	COG2197	response regulator
JKL50_RS18625	COG1846	Transcriptional regulator
JKL50_RS18630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JKL50_RS18635	COG5401	PFAM Sporulation and spore germination
JKL50_RS18640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JKL50_RS18645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JKL50_RS18650	COG0622	Phosphoesterase
JKL50_RS18695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JKL50_RS18700	COG1696	Membrane protein involved in D-alanine export
JKL50_RS18705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JKL50_RS18710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JKL50_RS18715	COG3339	Conserved Protein
JKL50_RS18720	COG2706	6-phosphogluconolactonase activity
JKL50_RS18725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JKL50_RS18730	COG0028	Belongs to the TPP enzyme family
JKL50_RS18735	COG0440	acetolactate synthase activity
JKL50_RS18740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JKL50_RS18745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JKL50_RS18750	COG0473	3-isopropylmalate dehydrogenase activity
JKL50_RS18755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JKL50_RS18760	COG0066	3-isopropylmalate dehydratase activity
JKL50_RS18765	COG0457	Tetratricopeptide repeat
JKL50_RS18765	COG1477	protein flavinylation
JKL50_RS18770	COG0544	peptidyl-prolyl cis-trans isomerase activity
JKL50_RS18775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JKL50_RS18780	COG1067	ATP-dependent peptidase activity
JKL50_RS18780	COG0470	DNA polymerase III
JKL50_RS18785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JKL50_RS18790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JKL50_RS18815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JKL50_RS18820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JKL50_RS18825	COG0181	hydroxymethylbilane synthase activity
JKL50_RS18830	COG1587	Uroporphyrinogen-III synthase
JKL50_RS18835	COG0113	porphobilinogen synthase activity
JKL50_RS18840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JKL50_RS18845	COG1388	LysM domain
JKL50_RS18850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JKL50_RS18860	COG0525	valine-tRNA ligase activity
JKL50_RS18865	COG0285	dihydrofolate synthase activity
JKL50_RS18880	COG0424	maF-like protein
JKL50_RS18885	COG2003	Belongs to the UPF0758 family
JKL50_RS18890	COG1077	Cell shape determining protein MreB Mrl
JKL50_RS18900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JKL50_RS18905	COG0850	regulation of cytokinetic process
JKL50_RS18910	COG2894	cell division
JKL50_RS18915	COG0739	heme binding
JKL50_RS18920	COG1994	Peptidase M50
JKL50_RS18925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JKL50_RS18930	COG2868	ribosomal protein
JKL50_RS18935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JKL50_RS18940	COG3290	protein histidine kinase activity
JKL50_RS18945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JKL50_RS18950	COG4492	Belongs to the UPF0735 family
JKL50_RS18955	COG0077	Prephenate dehydratase
JKL50_RS18960	COG1827	regulation of RNA biosynthetic process
JKL50_RS18965	COG1104	cysteine desulfurase activity
JKL50_RS18970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JKL50_RS18975	COG0157	Belongs to the NadC ModD family
JKL50_RS18980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JKL50_RS18985	COG1388	LysM domain
JKL50_RS19000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JKL50_RS19015	COG2112	serine threonine protein kinase
JKL50_RS19025	COG0632	four-way junction helicase activity
JKL50_RS19030	COG2255	four-way junction helicase activity
JKL50_RS19040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JKL50_RS19045	COG0343	queuine tRNA-ribosyltransferase activity
JKL50_RS19050	COG1862	Preprotein translocase
JKL50_RS19060	COG2323	membrane
JKL50_RS19065	COG2244	polysaccharide biosynthetic process
JKL50_RS19075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JKL50_RS19075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JKL50_RS19080	COG0490	domain, Protein
JKL50_RS19085	COG5416	Lipopolysaccharide assembly protein A domain
JKL50_RS19090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JKL50_RS19090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JKL50_RS19095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JKL50_RS19100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JKL50_RS19105	COG1490	D-aminoacyl-tRNA deacylase activity
JKL50_RS19110	COG4991	sh3 domain protein
JKL50_RS19110	COG3103	Sh3 type 3 domain protein
JKL50_RS19110	COG0860	N-Acetylmuramoyl-L-alanine amidase
JKL50_RS19120	COG0124	histidyl-tRNA synthetase
JKL50_RS19135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JKL50_RS19140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JKL50_RS19145	COG1959	2 iron, 2 sulfur cluster binding
JKL50_RS19150	COG1104	cysteine desulfurase activity
JKL50_RS19155	COG0482	sulfurtransferase activity
JKL50_RS19160	COG0457	Tetratricopeptide repeat
JKL50_RS19165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JKL50_RS19170	COG3881	PFAM PRC-barrel domain
JKL50_RS19185	COG0765	amino acid transport
JKL50_RS19190	COG0765	amino acid transport
JKL50_RS19195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JKL50_RS19200	COG1126	abc transporter atp-binding protein
JKL50_RS19205	COG0628	permease
JKL50_RS19210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JKL50_RS19215	COG4472	Bacterial protein of unknown function (DUF965)
JKL50_RS19220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JKL50_RS19225	COG3906	Belongs to the UPF0473 family
JKL50_RS19230	COG1268	BioY protein
JKL50_RS19235	COG0318	PFAM AMP-dependent synthetase and ligase
JKL50_RS19240	COG0183	Belongs to the thiolase family
JKL50_RS19245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JKL50_RS19250	COG4122	O-methyltransferase activity
JKL50_RS19255	COG0826	peptidase U32
JKL50_RS19260	COG0826	peptidase U32
JKL50_RS19265	COG0572	uridine kinase
JKL50_RS19270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JKL50_RS19275	COG0768	penicillin binding
JKL50_RS19290	COG2226	methyltransferase
JKL50_RS19295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JKL50_RS19300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JKL50_RS19305	COG0626	cystathionine gamma-synthase activity