locus-tag	class	description
EXD81_RS00010	COG0646	methionine synthase
EXD81_RS00010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXD81_RS00015	COG2153	protein acetylation
EXD81_RS00020	COG1357	PFAM Pentapeptide repeats (8 copies)
EXD81_RS00030	COG2318	DinB family
EXD81_RS00035	COG1917	Cupin 2, conserved barrel domain protein
EXD81_RS00035	COG2207	Transcriptional regulator
EXD81_RS00040	COG0534	Mate efflux family protein
EXD81_RS00045	COG1562	ergosterol biosynthetic process
EXD81_RS00070	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXD81_RS00110	COG1403	HNH endonuclease
EXD81_RS00135	COG2323	membrane
EXD81_RS00140	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXD81_RS00150	COG2814	Major facilitator Superfamily
EXD81_RS00155	COG3180	Ammonia monooxygenase
EXD81_RS00160	COG1846	Transcriptional regulator
EXD81_RS00165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXD81_RS00170	COG0681	Belongs to the peptidase S26 family
EXD81_RS00175	COG0398	Pfam SNARE associated Golgi protein
EXD81_RS00190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_RS00230	COG4903	ComK protein
EXD81_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS00255	COG1268	BioY protein
EXD81_RS00265	COG0183	Belongs to the thiolase family
EXD81_RS00270	COG0406	alpha-ribazole phosphatase activity
EXD81_RS00305	COG0702	epimerase
EXD81_RS00310	COG0095	Lipoate-protein ligase
EXD81_RS00315	COG1234	tRNA 3'-trailer cleavage
EXD81_RS00325	COG1301	dicarboxylic acid transport
EXD81_RS00330	COG1363	Peptidase, m42
EXD81_RS00340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXD81_RS00345	COG1511	domain protein
EXD81_RS00350	COG1309	transcriptional regulator
EXD81_RS00360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXD81_RS00370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_RS00375	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_RS00380	COG3069	C4-dicarboxylate transmembrane transporter activity
EXD81_RS00385	COG1473	amidohydrolase
EXD81_RS00395	COG4473	ABC transporter
EXD81_RS00400	COG1131	(ABC) transporter
EXD81_RS00405	COG0537	adenosine 5'-monophosphoramidase activity
EXD81_RS00410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EXD81_RS00465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXD81_RS00480	COG4717	serine-type aminopeptidase activity
EXD81_RS00485	COG0420	3'-5' exonuclease activity
EXD81_RS00490	COG1668	transmembrane transport
EXD81_RS00515	COG0490	domain, Protein
EXD81_RS00520	COG0475	glutathione-regulated potassium exporter activity
EXD81_RS00530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXD81_RS00535	COG0561	phosphatase activity
EXD81_RS00555	COG0189	ligase activity
EXD81_RS00580	COG0702	epimerase
EXD81_RS00585	COG1132	(ABC) transporter
EXD81_RS00590	COG1132	(ABC) transporter
EXD81_RS00595	COG0589	response to stress
EXD81_RS00610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_RS00615	COG0726	polysaccharide deacetylase
EXD81_RS00620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EXD81_RS00635	COG0584	glycerophosphoryl diester phosphodiesterase
EXD81_RS00640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXD81_RS00645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXD81_RS00650	COG1253	flavin adenine dinucleotide binding
EXD81_RS00655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXD81_RS00660	COG0436	Aminotransferase
EXD81_RS00665	COG0789	Transcriptional regulator
EXD81_RS00670	COG1253	flavin adenine dinucleotide binding
EXD81_RS00675	COG0204	Acyl-transferase
EXD81_RS00680	COG1595	DNA-templated transcription, initiation
EXD81_RS00695	COG0733	neurotransmitter:sodium symporter activity
EXD81_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS00710	COG0372	Belongs to the citrate synthase family
EXD81_RS00725	COG1785	Belongs to the alkaline phosphatase family
EXD81_RS00730	COG2719	SpoVR family
EXD81_RS00735	COG0668	transmembrane transport
EXD81_RS00745	COG1959	2 iron, 2 sulfur cluster binding
EXD81_RS00750	COG1388	LysM domain
EXD81_RS00750	COG0791	NLP P60 protein
EXD81_RS00765	COG0431	NADPH-dependent FMN reductase
EXD81_RS00770	COG2197	response regulator
EXD81_RS00775	COG2203	Gaf domain
EXD81_RS00775	COG4585	Histidine kinase
EXD81_RS00795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXD81_RS00800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXD81_RS00805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_RS00810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXD81_RS00810	COG3153	acetyltransferase
EXD81_RS00815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXD81_RS00820	COG0517	IMP dehydrogenase activity
EXD81_RS00830	COG0564	pseudouridine synthase activity
EXD81_RS00835	COG3764	Sortase (surface protein transpeptidase)
EXD81_RS00840	COG1525	nuclease
EXD81_RS00840	COG0737	Belongs to the 5'-nucleotidase family
EXD81_RS00840	COG4085	toxin activity
EXD81_RS00845	COG5577	PFAM Coat F domain
EXD81_RS00885	COG1278	Cold shock
EXD81_RS00890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_RS00895	COG1131	(ABC) transporter
EXD81_RS00900	COG1131	(ABC) transporter
EXD81_RS00905	COG1725	Transcriptional regulator
EXD81_RS00920	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXD81_RS00925	COG2814	Major facilitator Superfamily
EXD81_RS00930	COG1566	PFAM secretion protein HlyD family protein
EXD81_RS00935	COG1846	Transcriptional regulator
EXD81_RS00950	COG2766	serine protein kinase
EXD81_RS00955	COG1664	Polymer-forming cytoskeletal
EXD81_RS00960	COG1664	Polymer-forming cytoskeletal
EXD81_RS00965	COG0789	Transcriptional regulator
EXD81_RS00970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXD81_RS00995	COG1476	TRANSCRIPTIONal
EXD81_RS01015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXD81_RS01020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXD81_RS01025	COG1116	anion transmembrane transporter activity
EXD81_RS01040	COG0753	catalase activity
EXD81_RS01045	COG4608	Belongs to the ABC transporter superfamily
EXD81_RS01050	COG0444	Belongs to the ABC transporter superfamily
EXD81_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_RS01060	COG0601	transmembrane transport
EXD81_RS01065	COG0747	negative chemotaxis
EXD81_RS01075	COG0277	FAD linked oxidase domain protein
EXD81_RS01085	COG3340	Belongs to the peptidase S51 family
EXD81_RS01090	COG1757	Na H antiporter
EXD81_RS01200	COG0735	belongs to the Fur family
EXD81_RS01205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXD81_RS01215	COG4129	membrane
EXD81_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS01255	COG1988	membrane-bound metal-dependent
EXD81_RS01260	COG4485	Bacterial membrane protein, YfhO
EXD81_RS01275	COG0596	Alpha beta hydrolase
EXD81_RS01280	COG5658	integral membrane protein
EXD81_RS01285	COG3103	Sh3 type 3 domain protein
EXD81_RS01300	COG3591	Belongs to the peptidase S1B family
EXD81_RS01325	COG1090	epimerase
EXD81_RS01340	COG0778	Nitroreductase
EXD81_RS01345	COG0384	phenazine biosynthesis protein PhzF
EXD81_RS01350	COG0392	lysyltransferase activity
EXD81_RS01350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXD81_RS01355	COG1846	Transcriptional regulator
EXD81_RS01360	COG2814	Major facilitator Superfamily
EXD81_RS01365	COG2318	DinB family
EXD81_RS01370	COG2732	(Barnase) inhibitor
EXD81_RS01380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EXD81_RS01390	COG1695	Transcriptional regulator
EXD81_RS01405	COG2514	catechol 2,3-dioxygenase activity
EXD81_RS01410	COG2259	Doxx family
EXD81_RS01415	COG1132	(ABC) transporter
EXD81_RS01420	COG1132	(ABC) transporter
EXD81_RS01425	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_RS01435	COG1737	Transcriptional regulator
EXD81_RS01440	COG1486	melibiose metabolic process
EXD81_RS01450	COG3284	Transcriptional regulator
EXD81_RS01460	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_RS01465	COG0022	dehydrogenase e1 component
EXD81_RS01470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_RS01475	COG4637	Psort location Cytoplasmic, score
EXD81_RS01480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXD81_RS01495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXD81_RS01500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXD81_RS01505	COG0598	Magnesium transport protein CorA
EXD81_RS01515	COG2084	Dehydrogenase
EXD81_RS01520	COG0726	polysaccharide deacetylase
EXD81_RS01530	COG0535	radical SAM domain protein
EXD81_RS01545	COG0387	Pfam Sodium calcium exchanger
EXD81_RS01550	COG0477	Major facilitator Superfamily
EXD81_RS01555	COG1295	ribonuclease BN
EXD81_RS01560	COG4980	gas vesicle protein
EXD81_RS01565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXD81_RS01575	COG2814	Major facilitator Superfamily
EXD81_RS01590	COG1609	Transcriptional regulator
EXD81_RS01595	COG0693	protein deglycase activity
EXD81_RS01615	COG0778	Nitroreductase
EXD81_RS01620	COG2188	Transcriptional regulator
EXD81_RS01625	COG0366	Alpha amylase catalytic
EXD81_RS01630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS01630	COG1263	PTS System
EXD81_RS01645	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_RS01655	COG1368	sulfuric ester hydrolase activity
EXD81_RS01665	COG1263	PTS System
EXD81_RS01665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS01670	COG0024	Methionine aminopeptidase
EXD81_RS01690	COG2258	MOSC domain
EXD81_RS01700	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXD81_RS01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS01715	COG3181	Tripartite tricarboxylate transporter family receptor
EXD81_RS01720	COG4565	transcriptional regulatory protein
EXD81_RS01755	COG3866	Pectate lyase
EXD81_RS01775	COG0456	acetyltransferase
EXD81_RS01780	COG0513	Belongs to the DEAD box helicase family
EXD81_RS01790	COG2814	Major facilitator Superfamily
EXD81_RS01795	COG0789	Transcriptional regulator
EXD81_RS01800	COG0488	(ABC) transporter
EXD81_RS01805	COG0457	Tetratricopeptide repeat
EXD81_RS01805	COG0463	Glycosyl transferase, family 2
EXD81_RS01810	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS01815	COG0840	transmembrane signaling receptor activity
EXD81_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_RS01825	COG0531	amino acid
EXD81_RS01830	COG2223	nitrite transmembrane transporter activity
EXD81_RS01835	COG1442	glycosyl transferase family 8
EXD81_RS01840	COG1216	Glycosyl transferase, family 2
EXD81_RS01845	COG1442	glycosyl transferase family 8
EXD81_RS01850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXD81_RS01855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXD81_RS01860	COG1368	sulfuric ester hydrolase activity
EXD81_RS01875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXD81_RS01880	COG1846	Transcriptional regulator
EXD81_RS01885	COG0670	Belongs to the BI1 family
EXD81_RS01890	COG0196	riboflavin kinase activity
EXD81_RS01895	COG5583	Uncharacterized small protein (DUF2292)
EXD81_RS01905	COG0346	lactoylglutathione lyase activity
EXD81_RS01910	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_RS01915	COG2323	membrane
EXD81_RS01925	COG0454	-acetyltransferase
EXD81_RS01970	COG5444	nuclease activity
EXD81_RS02020	COG1131	(ABC) transporter
EXD81_RS02030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXD81_RS02035	COG1597	lipid kinase activity
EXD81_RS02040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXD81_RS02045	COG1309	transcriptional regulator
EXD81_RS02065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_RS02095	COG0210	DNA helicase
EXD81_RS02110	COG4496	protein, YerC YecD
EXD81_RS02115	COG1470	cell adhesion involved in biofilm formation
EXD81_RS02130	COG0151	Belongs to the GarS family
EXD81_RS02135	COG0138	bifunctional purine biosynthesis protein purh
EXD81_RS02140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXD81_RS02150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXD81_RS02165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXD81_RS02175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXD81_RS02180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXD81_RS02185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXD81_RS02210	COG2252	PERMEase
EXD81_RS02240	COG0714	Associated with various cellular activities
EXD81_RS02245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_RS02250	COG1113	amino acid transport
EXD81_RS02255	COG2132	Multicopper oxidase
EXD81_RS02265	COG0823	Involved in the tonB-independent uptake of proteins
EXD81_RS02270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EXD81_RS02275	COG1063	alcohol dehydrogenase
EXD81_RS02280	COG1595	DNA-templated transcription, initiation
EXD81_RS02295	COG4260	virion core protein, lumpy skin disease virus
EXD81_RS02305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXD81_RS02310	COG1842	Phage shock protein A
EXD81_RS02320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXD81_RS02330	COG1063	alcohol dehydrogenase
EXD81_RS02375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXD81_RS02390	COG0488	(ABC) transporter
EXD81_RS02400	COG0456	acetyltransferase
EXD81_RS02405	COG1214	PFAM Peptidase M22, glycoprotease
EXD81_RS02410	COG0802	atpase or kinase
EXD81_RS02455	COG2814	Major facilitator Superfamily
EXD81_RS02460	COG0604	alcohol dehydrogenase
EXD81_RS02465	COG3832	glyoxalase III activity
EXD81_RS02475	COG0531	amino acid
EXD81_RS02480	COG1309	transcriptional regulator
EXD81_RS02485	COG2076	Multidrug Resistance protein
EXD81_RS02490	COG2076	Multidrug Resistance protein
EXD81_RS02495	COG2807	transmembrane transport
EXD81_RS02500	COG2186	Transcriptional regulator
EXD81_RS02505	COG2188	Transcriptional regulator
EXD81_RS02510	COG2814	Major facilitator Superfamily
EXD81_RS02515	COG1388	LysM domain
EXD81_RS02520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_RS02535	COG1819	glycosyl
EXD81_RS02555	COG1051	belongs to the nudix hydrolase family
EXD81_RS02565	COG0789	Transcriptional regulator
EXD81_RS02565	COG4978	Transcriptional regulator
EXD81_RS02570	COG0456	acetyltransferase
EXD81_RS02575	COG0730	response to heat
EXD81_RS02585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXD81_RS02590	COG2814	Major facilitator Superfamily
EXD81_RS02600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_RS02620	COG2409	Drug exporters of the RND superfamily
EXD81_RS02625	COG2197	response regulator
EXD81_RS02630	COG4585	Histidine kinase
EXD81_RS02640	COG5577	PFAM Coat F domain
EXD81_RS02645	COG1063	alcohol dehydrogenase
EXD81_RS02655	COG5577	PFAM Coat F domain
EXD81_RS02665	COG0697	spore germination
EXD81_RS02670	COG1309	transcriptional regulator
EXD81_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_RS02700	COG0789	Transcriptional regulator
EXD81_RS02705	COG1064	alcohol dehydrogenase
EXD81_RS02730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXD81_RS02735	COG2318	DinB family
EXD81_RS02740	COG0662	Cupin 2, conserved barrel domain protein
EXD81_RS02765	COG0277	FAD linked oxidase domain protein
EXD81_RS02780	COG0662	Cupin 2, conserved barrel domain protein
EXD81_RS02790	COG3621	Patatin-like phospholipase
EXD81_RS02795	COG2271	Major facilitator Superfamily
EXD81_RS02820	COG0730	response to heat
EXD81_RS02825	COG0425	Belongs to the sulfur carrier protein TusA family
EXD81_RS02830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_RS02830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS02835	COG0425	Belongs to the sulfur carrier protein TusA family
EXD81_RS02835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_RS02845	COG2210	Belongs to the sulfur carrier protein TusA family
EXD81_RS02850	COG1937	Protein conserved in bacteria
EXD81_RS02855	COG1329	Transcriptional regulator
EXD81_RS02860	COG1278	Cold shock
EXD81_RS02895	COG0351	phosphomethylpyrimidine kinase
EXD81_RS02930	COG1959	2 iron, 2 sulfur cluster binding
EXD81_RS02945	COG2030	dehydratase
EXD81_RS02955	COG1522	sequence-specific DNA binding
EXD81_RS02970	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXD81_RS02985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EXD81_RS03000	COG1959	2 iron, 2 sulfur cluster binding
EXD81_RS03020	COG0604	alcohol dehydrogenase
EXD81_RS03085	COG0582	viral genome integration into host DNA
EXD81_RS03135	COG2183	response to ionizing radiation
EXD81_RS03140	COG2208	phosphoserine phosphatase activity
EXD81_RS03145	COG1191	sigma factor activity
EXD81_RS03155	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS03165	COG2172	sigma factor antagonist activity
EXD81_RS03170	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS03175	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS03180	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXD81_RS03185	COG0864	Transcriptional regulator
EXD81_RS03190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXD81_RS03195	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXD81_RS03205	COG0705	Rhomboid family
EXD81_RS03210	COG3428	Bacterial PH domain
EXD81_RS03215	COG3402	PFAM membrane-flanked domain
EXD81_RS03220	COG0513	Belongs to the DEAD box helicase family
EXD81_RS03225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXD81_RS03235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS03240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_RS03255	COG1960	acyl-CoA dehydrogenase activity
EXD81_RS03265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_RS03270	COG1131	(ABC) transporter
EXD81_RS03275	COG0628	permease
EXD81_RS03280	COG1301	dicarboxylic acid transport
EXD81_RS03285	COG4565	transcriptional regulatory protein
EXD81_RS03290	COG3290	protein histidine kinase activity
EXD81_RS03295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EXD81_RS03300	COG3546	catalase activity
EXD81_RS03305	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_RS03310	COG0662	Cupin 2, conserved barrel domain protein
EXD81_RS03315	COG3729	General stress protein
EXD81_RS03320	COG2217	Heavy metal translocating P-type atpase
EXD81_RS03325	COG2076	Multidrug Resistance protein
EXD81_RS03335	COG4876	unkown
EXD81_RS03350	COG1914	H( )-stimulated, divalent metal cation uptake system
EXD81_RS03390	COG0028	Belongs to the TPP enzyme family
EXD81_RS03395	COG0494	nUDIX hydrolase
EXD81_RS03400	COG0531	amino acid
EXD81_RS03410	COG1215	transferase activity, transferring glycosyl groups
EXD81_RS03420	COG3706	GGDEF domain
EXD81_RS03425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXD81_RS03440	COG2814	Major facilitator Superfamily
EXD81_RS03450	COG3871	stress protein (general stress protein 26)
EXD81_RS03460	COG1917	Cupin 2, conserved barrel domain protein
EXD81_RS03465	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS03470	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_RS03475	COG3711	transcriptional antiterminator
EXD81_RS03480	COG4989	oxidoreductase activity
EXD81_RS03485	COG0768	penicillin binding
EXD81_RS03490	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_RS03500	COG2755	lipolytic protein G-D-S-L family
EXD81_RS03505	COG1414	Transcriptional regulator
EXD81_RS03525	COG1914	H( )-stimulated, divalent metal cation uptake system
EXD81_RS03535	COG0561	phosphatase activity
EXD81_RS03545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXD81_RS03555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS03570	COG1349	DNA-binding transcription factor activity
EXD81_RS03575	COG2372	response to copper ion
EXD81_RS03575	COG1276	copper resistance
EXD81_RS03580	COG4549	nuclear export factor GLE1
EXD81_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS03590	COG4975	Glucose uptake
EXD81_RS03600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXD81_RS03605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_RS03610	COG0640	Transcriptional regulator
EXD81_RS03615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXD81_RS03620	COG0778	Nitroreductase
EXD81_RS03625	COG1309	transcriptional regulator
EXD81_RS03630	COG2814	Major facilitator Superfamily
EXD81_RS03640	COG4604	ABC transporter, ATP-binding protein
EXD81_RS03650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_RS03655	COG0527	aspartate kinase activity
EXD81_RS03670	COG0457	Tetratricopeptide repeat
EXD81_RS03685	COG0577	efflux transmembrane transporter activity
EXD81_RS03690	COG1136	(ABC) transporter
EXD81_RS03695	COG2079	MmgE PrpD family protein
EXD81_RS03700	COG1473	amidohydrolase
EXD81_RS03705	COG1126	abc transporter atp-binding protein
EXD81_RS03710	COG0765	amino acid transport
EXD81_RS03715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_RS03725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_RS03730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EXD81_RS03740	COG0697	spore germination
EXD81_RS03750	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_RS03755	COG3104	oligopeptide transport
EXD81_RS03770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EXD81_RS03775	COG0163	prenyltransferase activity
EXD81_RS03780	COG0583	DNA-binding transcription factor activity
EXD81_RS03785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_RS03790	COG0765	amino acid transport
EXD81_RS03795	COG1126	abc transporter atp-binding protein
EXD81_RS03805	COG2364	Membrane
EXD81_RS03820	COG0697	spore germination
EXD81_RS03830	COG2814	Major facilitator Superfamily
EXD81_RS03835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXD81_RS03840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS03855	COG1733	regulation of RNA biosynthetic process
EXD81_RS03870	COG3209	COG3209 Rhs family protein
EXD81_RS03880	COG2723	6-phospho-beta-galactosidase activity
EXD81_RS03900	COG0523	cobalamin synthesis protein
EXD81_RS03905	COG2223	nitrite transmembrane transporter activity
EXD81_RS03910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXD81_RS03920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXD81_RS03925	COG2146	nitrite reductase [NAD(P)H] activity
EXD81_RS03940	COG2508	Transcriptional regulator
EXD81_RS03945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_RS03950	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_RS03955	COG0506	proline dehydrogenase activity
EXD81_RS03960	COG3541	Predicted nucleotidyltransferase
EXD81_RS03965	COG3458	cephalosporin-C deacetylase activity
EXD81_RS03975	COG2271	Major facilitator Superfamily
EXD81_RS03980	COG1082	Xylose isomerase domain protein TIM barrel
EXD81_RS03985	COG1660	Displays ATPase and GTPase activities
EXD81_RS04000	COG3665	Urea carboxylase-associated protein
EXD81_RS04005	COG1113	amino acid transport
EXD81_RS04010	COG3403	YqcI/YcgG family
EXD81_RS04015	COG1280	lysine exporter protein (LysE YggA)
EXD81_RS04020	COG1846	Transcriptional regulator
EXD81_RS04025	COG2814	Major facilitator Superfamily
EXD81_RS04035	COG0366	Alpha amylase catalytic
EXD81_RS04045	COG1288	antiporter activity
EXD81_RS04050	COG1473	amidohydrolase
EXD81_RS04055	COG2113	Glycine betaine
EXD81_RS04060	COG4176	ABC-type proline glycine betaine transport system permease component
EXD81_RS04065	COG0517	IMP dehydrogenase activity
EXD81_RS04065	COG4175	Glycine betaine
EXD81_RS04070	COG0477	Major facilitator Superfamily
EXD81_RS04075	COG3853	Toxic anion resistance protein (TelA)
EXD81_RS04085	COG0861	Integral membrane protein TerC family
EXD81_RS04090	COG2310	stress, protein
EXD81_RS04095	COG2310	stress, protein
EXD81_RS04100	COG2310	stress, protein
EXD81_RS04105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_RS04110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXD81_RS04120	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXD81_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS04135	COG0457	Tetratricopeptide repeat
EXD81_RS04140	COG1876	peptidase activity
EXD81_RS04145	COG1595	DNA-templated transcription, initiation
EXD81_RS04160	COG0667	Aldo Keto reductase
EXD81_RS04165	COG1405	negative regulation of cell septum assembly
EXD81_RS04165	COG3012	SEC-C Motif Domain Protein
EXD81_RS04170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EXD81_RS04185	COG0477	Major facilitator Superfamily
EXD81_RS04190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXD81_RS04200	COG0805	protein transport
EXD81_RS04205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXD81_RS04210	COG3540	Alkaline phosphatase
EXD81_RS04220	COG3773	Cell wall hydrolase
EXD81_RS04235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS04240	COG2259	Doxx family
EXD81_RS04245	COG0346	lactoylglutathione lyase activity
EXD81_RS04255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_RS04280	COG4191	Histidine kinase
EXD81_RS04285	COG2066	Belongs to the glutaminase family
EXD81_RS04290	COG1115	amino acid carrier protein
EXD81_RS04295	COG2040	homocysteine
EXD81_RS04310	COG1301	dicarboxylic acid transport
EXD81_RS04325	COG0688	phosphatidylethanolamine metabolic process
EXD81_RS04330	COG0586	Pfam SNARE associated Golgi protein
EXD81_RS04335	COG1183	phosphatidylcholine synthase activity
EXD81_RS04345	COG0371	Dehydrogenase
EXD81_RS04360	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS04395	COG0584	glycerophosphoryl diester phosphodiesterase
EXD81_RS04410	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EXD81_RS04455	COG1131	(ABC) transporter
EXD81_RS04460	COG2197	response regulator
EXD81_RS04470	COG1011	Hydrolase
EXD81_RS04475	COG1113	amino acid transport
EXD81_RS04480	COG1846	Transcriptional regulator
EXD81_RS04485	COG1380	Effector of murein hydrolase LrgA
EXD81_RS04490	COG1346	cytolysis
EXD81_RS04535	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXD81_RS04545	COG1595	DNA-templated transcription, initiation
EXD81_RS04575	COG1683	Conserved Protein
EXD81_RS04580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_RS04590	COG1263	PTS System
EXD81_RS04590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS04605	COG3876	Protein conserved in bacteria
EXD81_RS04610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_RS04610	COG2207	Transcriptional regulator
EXD81_RS04625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_RS04630	COG2819	hydrolase of the alpha beta superfamily
EXD81_RS04635	COG0385	Bile acid
EXD81_RS04640	COG0659	secondary active sulfate transmembrane transporter activity
EXD81_RS04655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXD81_RS04660	COG0738	Major facilitator superfamily
EXD81_RS04720	COG0726	polysaccharide deacetylase
EXD81_RS04725	COG2194	sulfuric ester hydrolase activity
EXD81_RS04735	COG0489	protein tyrosine kinase activity
EXD81_RS04740	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS04755	COG2226	methyltransferase
EXD81_RS04780	COG1122	ATPase activity
EXD81_RS04785	COG1122	ATPase activity
EXD81_RS04810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXD81_RS04825	COG0024	Methionine aminopeptidase
EXD81_RS04945	COG0596	Alpha beta hydrolase
EXD81_RS04970	COG1358	cellular component organization or biogenesis
EXD81_RS05010	COG0250	Participates in transcription elongation, termination and antitermination
EXD81_RS05035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXD81_RS05040	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EXD81_RS05070	COG4956	integral membrane protein (PIN domain superfamily)
EXD81_RS05100	COG4463	regulation of RNA biosynthetic process
EXD81_RS05180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXD81_RS05190	COG1396	sequence-specific DNA binding
EXD81_RS05200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXD81_RS05210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_RS05215	COG0512	Glutamine amidotransferase of anthranilate synthase
EXD81_RS05220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXD81_RS05225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_RS05230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXD81_RS05250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXD81_RS05255	COG0037	tRNA processing
EXD81_RS05260	COG0515	serine threonine protein kinase
EXD81_RS05265	COG2304	oxidoreductase activity
EXD81_RS05285	COG1098	S1 RNA binding domain
EXD81_RS05290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EXD81_RS05305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXD81_RS05320	COG2002	toxin-antitoxin pair type II binding
EXD81_RS05325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXD81_RS05345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EXD81_RS05360	COG0251	oxidation-reduction process
EXD81_RS05365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXD81_RS05380	COG4466	Protein conserved in bacteria
EXD81_RS05395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXD81_RS05405	COG0084	hydrolase, TatD family'
EXD81_RS05415	COG2002	toxin-antitoxin pair type II binding
EXD81_RS05420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXD81_RS05430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXD81_RS05440	COG1774	PSP1 C-terminal conserved region
EXD81_RS05455	COG3870	Protein conserved in bacteria
EXD81_RS05465	COG1982	Orn Lys Arg decarboxylase major
EXD81_RS05470	COG3853	Toxic anion resistance protein (TelA)
EXD81_RS05475	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EXD81_RS05530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXD81_RS05540	COG0590	tRNA wobble adenosine to inosine editing
EXD81_RS05545	COG1335	isochorismatase
EXD81_RS05550	COG1388	LysM domain
EXD81_RS05550	COG3858	chitin binding
EXD81_RS05555	COG1428	Deoxynucleoside kinase
EXD81_RS05560	COG1428	Deoxynucleoside kinase
EXD81_RS05570	COG1929	Belongs to the glycerate kinase type-1 family
EXD81_RS05590	COG1686	Belongs to the peptidase S11 family
EXD81_RS05630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXD81_RS05650	COG2501	S4 domain
EXD81_RS05655	COG0592	DNA-directed DNA polymerase activity
EXD81_RS05675	COG0706	membrane insertase activity
EXD81_RS05680	COG1847	R3H domain protein
EXD81_RS05705	COG1192	Involved in chromosome partitioning
EXD81_RS05725	COG3949	Membrane
EXD81_RS05730	COG4481	Protein conserved in bacteria
EXD81_RS05740	COG0012	GTP binding
EXD81_RS05750	COG0629	single-stranded DNA binding
EXD81_RS05760	COG2169	Transcriptional regulator
EXD81_RS05765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXD81_RS05770	COG0708	Exodeoxyribonuclease III
EXD81_RS05775	COG1609	Transcriptional regulator
EXD81_RS05780	COG0346	lactoylglutathione lyase activity
EXD81_RS05790	COG1266	CAAX protease self-immunity
EXD81_RS05795	COG1331	Highly conserved protein containing a thioredoxin domain
EXD81_RS05800	COG0697	spore germination
EXD81_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS05820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXD81_RS05830	COG2153	protein acetylation
EXD81_RS05840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS05845	COG1846	Transcriptional regulator
EXD81_RS05850	COG0778	Nitroreductase
EXD81_RS05860	COG0583	DNA-binding transcription factor activity
EXD81_RS05865	COG2814	Major facilitator Superfamily
EXD81_RS05875	COG0583	DNA-binding transcription factor activity
EXD81_RS05880	COG2211	Major facilitator Superfamily
EXD81_RS05890	COG1802	Transcriptional regulator
EXD81_RS05895	COG1621	beta-fructofuranosidase activity
EXD81_RS05920	COG5577	PFAM Coat F domain
EXD81_RS05935	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXD81_RS05955	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS05970	COG0297	glycogen (starch) synthase activity
EXD81_RS05975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EXD81_RS05980	COG3093	addiction module antidote protein HigA
EXD81_RS06000	COG0305	Participates in initiation and elongation during chromosome replication
EXD81_RS06005	COG0346	lactoylglutathione lyase activity
EXD81_RS06040	COG0745	RESPONSE REGULATOR receiver
EXD81_RS06045	COG5002	protein histidine kinase activity
EXD81_RS06050	COG4863	YycH protein
EXD81_RS06055	COG4853	Protein conserved in bacteria
EXD81_RS06060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXD81_RS06075	COG3850	Histidine kinase
EXD81_RS06075	COG5002	protein histidine kinase activity
EXD81_RS06080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_RS06095	COG0488	(ABC) transporter
EXD81_RS06105	COG3829	transcription factor binding
EXD81_RS06110	COG0640	Transcriptional regulator
EXD81_RS06115	COG5658	integral membrane protein
EXD81_RS06120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXD81_RS06125	COG0833	amino acid
EXD81_RS06130	COG0010	Belongs to the arginase family
EXD81_RS06135	COG0457	Tetratricopeptide repeat
EXD81_RS06140	COG0456	acetyltransferase
EXD81_RS06145	COG0667	Aldo Keto reductase
EXD81_RS06150	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EXD81_RS06245	COG2080	2 iron, 2 sulfur cluster binding
EXD81_RS06260	COG3634	alkyl hydroperoxide reductase activity
EXD81_RS06265	COG0450	alkyl hydroperoxide reductase
EXD81_RS06275	COG1714	RDD family
EXD81_RS06280	COG2814	Major facilitator Superfamily
EXD81_RS06285	COG0640	Transcriptional regulator
EXD81_RS06315	COG3239	Fatty acid desaturase
EXD81_RS06325	COG2197	response regulator
EXD81_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS06345	COG2814	Major facilitator Superfamily
EXD81_RS06355	COG1349	DNA-binding transcription factor activity
EXD81_RS06395	COG1082	Xylose isomerase domain protein TIM barrel
EXD81_RS06425	COG0745	RESPONSE REGULATOR receiver
EXD81_RS06440	COG2205	protein histidine kinase activity
EXD81_RS06445	COG1136	(ABC) transporter
EXD81_RS06450	COG0577	efflux transmembrane transporter activity
EXD81_RS06455	COG5294	Protein conserved in bacteria
EXD81_RS06460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_RS06490	COG0561	phosphatase activity
EXD81_RS06495	COG2390	Transcriptional regulator
EXD81_RS06505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXD81_RS06510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXD81_RS06515	COG0833	amino acid
EXD81_RS06520	COG0010	Belongs to the arginase family
EXD81_RS06545	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_RS06550	COG0494	nUDIX hydrolase
EXD81_RS06565	COG2190	(PTS) system
EXD81_RS06565	COG1263	PTS System
EXD81_RS06565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS06570	COG2723	6-phospho-beta-galactosidase activity
EXD81_RS06575	COG0589	response to stress
EXD81_RS06630	COG0513	Belongs to the DEAD box helicase family
EXD81_RS06635	COG2270	Major facilitator Superfamily
EXD81_RS06640	COG3711	transcriptional antiterminator
EXD81_RS06645	COG2273	Hydrolase Family 16
EXD81_RS06675	COG0500	methyltransferase
EXD81_RS06680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXD81_RS06685	COG4894	glucomannan catabolic process
EXD81_RS06695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXD81_RS06705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS06710	COG2508	Transcriptional regulator
EXD81_RS06715	COG3842	ATPase activity
EXD81_RS06720	COG0726	polysaccharide deacetylase
EXD81_RS06725	COG3493	citrate carrier protein
EXD81_RS06730	COG1271	oxidase subunit
EXD81_RS06735	COG1294	oxidase, subunit
EXD81_RS06745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXD81_RS06750	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EXD81_RS06760	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXD81_RS06765	COG0753	catalase activity
EXD81_RS06775	COG1482	cell wall glycoprotein biosynthetic process
EXD81_RS06780	COG1940	carbohydrate kinase activity
EXD81_RS06790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_RS06795	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXD81_RS06800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_RS06810	COG0640	Transcriptional regulator
EXD81_RS06820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_RS06835	COG3711	transcriptional antiterminator
EXD81_RS06835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS06840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_RS06845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_RS06855	COG1486	melibiose metabolic process
EXD81_RS06860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_RS06865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXD81_RS06875	COG1696	Membrane protein involved in D-alanine export
EXD81_RS06895	COG1575	Belongs to the MenA family. Type 1 subfamily
EXD81_RS06900	COG2357	RelA SpoT domain protein
EXD81_RS06905	COG1442	glycosyl transferase family 8
EXD81_RS06910	COG1404	Belongs to the peptidase S8 family
EXD81_RS06915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_RS06920	COG0346	lactoylglutathione lyase activity
EXD81_RS06925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXD81_RS06935	COG0789	Transcriptional regulator
EXD81_RS06940	COG4895	conserved protein (DUF2196)
EXD81_RS06945	COG1346	cytolysis
EXD81_RS06955	COG0583	DNA-binding transcription factor activity
EXD81_RS06970	COG2822	iron ion transport
EXD81_RS06975	COG2837	iron assimilation
EXD81_RS06980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXD81_RS07000	COG1309	transcriptional regulator
EXD81_RS07005	COG2246	polysaccharide biosynthetic process
EXD81_RS07015	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXD81_RS07020	COG2261	transglycosylase associated protein
EXD81_RS07025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXD81_RS07030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXD81_RS07050	COG0454	-acetyltransferase
EXD81_RS07065	COG0778	Nitroreductase
EXD81_RS07070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_RS07085	COG3711	transcriptional antiterminator
EXD81_RS07090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS07090	COG1263	PTS System
EXD81_RS07095	COG1621	beta-fructofuranosidase activity
EXD81_RS07105	COG0351	phosphomethylpyrimidine kinase
EXD81_RS07110	COG1695	Transcriptional regulator
EXD81_RS07125	COG1216	Glycosyl transferase, family 2
EXD81_RS07145	COG2363	Small membrane protein
EXD81_RS07155	COG0463	Glycosyl transferase, family 2
EXD81_RS07165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_RS07170	COG0456	acetyltransferase
EXD81_RS07175	COG2089	acid synthase
EXD81_RS07180	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EXD81_RS07185	COG3980	spore coat polysaccharide biosynthesis protein
EXD81_RS07190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXD81_RS07195	COG1088	dTDP-glucose 4,6-dehydratase activity
EXD81_RS07200	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXD81_RS07205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EXD81_RS07215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_RS07220	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_RS07230	COG0833	amino acid
EXD81_RS07270	COG0436	Aminotransferase
EXD81_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS07285	COG0280	phosphate acetyltransferase
EXD81_RS07290	COG2855	membrane
EXD81_RS07295	COG0583	DNA-binding transcription factor activity
EXD81_RS07320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_RS07325	COG1131	(ABC) transporter
EXD81_RS07335	COG1695	Transcriptional regulator
EXD81_RS07350	COG1078	dGTPase activity
EXD81_RS07360	COG0531	amino acid
EXD81_RS07370	COG1846	Transcriptional regulator
EXD81_RS07375	COG1942	4-Oxalocrotonate Tautomerase
EXD81_RS07380	COG1994	Peptidase M50
EXD81_RS07395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_RS07400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXD81_RS07460	COG3391	amine dehydrogenase activity
EXD81_RS07465	COG3391	amine dehydrogenase activity
EXD81_RS07475	COG4506	Protein conserved in bacteria
EXD81_RS07485	COG2223	nitrite transmembrane transporter activity
EXD81_RS07500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXD81_RS07520	COG2181	nitrate reductase activity
EXD81_RS07550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXD81_RS07555	COG0247	lactate metabolic process
EXD81_RS07555	COG2181	nitrate reductase activity
EXD81_RS07570	COG4821	SIS domain
EXD81_RS07575	COG2204	response regulator
EXD81_RS07580	COG0191	fructose-bisphosphate aldolase activity
EXD81_RS07590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EXD81_RS07615	COG0281	malic enzyme
EXD81_RS07620	COG0679	Auxin Efflux Carrier
EXD81_RS07625	COG0789	Transcriptional regulator
EXD81_RS07630	COG0346	lactoylglutathione lyase activity
EXD81_RS07635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXD81_RS07660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EXD81_RS07665	COG0009	L-threonylcarbamoyladenylate synthase
EXD81_RS07675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXD81_RS07680	COG0698	ribose 5-phosphate isomerase
EXD81_RS07750	COG4836	Membrane
EXD81_RS07760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EXD81_RS07765	COG2385	sporulation resulting in formation of a cellular spore
EXD81_RS07775	COG2304	oxidoreductase activity
EXD81_RS07780	COG2304	oxidoreductase activity
EXD81_RS07785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXD81_RS07795	COG0457	Tetratricopeptide repeat
EXD81_RS07800	COG1994	Peptidase M50
EXD81_RS07805	COG3237	CsbD-like
EXD81_RS07810	COG0831	urea catabolic process
EXD81_RS07825	COG1959	2 iron, 2 sulfur cluster binding
EXD81_RS07835	COG0726	polysaccharide deacetylase
EXD81_RS07865	COG1247	-acetyltransferase
EXD81_RS07870	COG0739	heme binding
EXD81_RS07880	COG0671	phosphoesterase, PA-phosphatase related
EXD81_RS07885	COG0772	Belongs to the SEDS family
EXD81_RS07890	COG0347	Belongs to the P(II) protein family
EXD81_RS07895	COG0004	ammonium transporteR
EXD81_RS07900	COG1335	isochorismatase
EXD81_RS07910	COG1953	Uracil, thiamine, allantoin
EXD81_RS07915	COG2814	Major facilitator Superfamily
EXD81_RS07920	COG1846	Transcriptional regulator
EXD81_RS07925	COG1609	Transcriptional regulator
EXD81_RS07930	COG1077	Cell shape determining protein MreB Mrl
EXD81_RS07935	COG4786	Flagellar basal body rod
EXD81_RS07940	COG4786	Flagellar basal body rod
EXD81_RS07945	COG0457	Tetratricopeptide repeat
EXD81_RS07970	COG0629	single-stranded DNA binding
EXD81_RS07975	COG1349	DNA-binding transcription factor activity
EXD81_RS07980	COG0561	phosphatase activity
EXD81_RS07990	COG4715	Zinc finger, swim domain protein
EXD81_RS08005	COG3944	biosynthesis protein
EXD81_RS08010	COG0489	protein tyrosine kinase activity
EXD81_RS08020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXD81_RS08025	COG3878	Protein conserved in bacteria
EXD81_RS08090	COG2059	Chromate
EXD81_RS08095	COG2059	Chromate
EXD81_RS08100	COG1522	sequence-specific DNA binding
EXD81_RS08105	COG0405	Gamma-glutamyltransferase
EXD81_RS08115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXD81_RS08125	COG5337	Spore coat protein CotH
EXD81_RS08140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXD81_RS08145	COG0583	DNA-binding transcription factor activity
EXD81_RS08150	COG0028	Belongs to the TPP enzyme family
EXD81_RS08155	COG3527	Alpha-acetolactate decarboxylase
EXD81_RS08160	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXD81_RS08165	COG3103	Sh3 type 3 domain protein
EXD81_RS08170	COG1879	ABC-type sugar transport system periplasmic component
EXD81_RS08175	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXD81_RS08180	COG1129	ABC transporter
EXD81_RS08195	COG1609	Transcriptional regulator
EXD81_RS08205	COG0697	spore germination
EXD81_RS08215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXD81_RS08225	COG2843	Capsule synthesis protein
EXD81_RS08230	COG0791	NLP P60 protein
EXD81_RS08240	COG0561	phosphatase activity
EXD81_RS08245	COG1316	TRANSCRIPTIONal
EXD81_RS08250	COG2814	Major facilitator Superfamily
EXD81_RS08255	COG1215	transferase activity, transferring glycosyl groups
EXD81_RS08265	COG0814	amino acid
EXD81_RS08270	COG0697	spore germination
EXD81_RS08275	COG1482	cell wall glycoprotein biosynthetic process
EXD81_RS08280	COG4193	domain, Protein
EXD81_RS08290	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EXD81_RS08310	COG1682	transport, permease protein
EXD81_RS08315	COG1134	teichoic acid transport
EXD81_RS08355	COG2244	polysaccharide biosynthetic process
EXD81_RS08360	COG0297	glycogen (starch) synthase activity
EXD81_RS08360	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS08365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXD81_RS08370	COG3307	-O-antigen
EXD81_RS08375	COG3206	protein involved in exopolysaccharide biosynthesis
EXD81_RS08380	COG1215	transferase activity, transferring glycosyl groups
EXD81_RS08385	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS08390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXD81_RS08395	COG1316	TRANSCRIPTIONal
EXD81_RS08405	COG4585	Histidine kinase
EXD81_RS08410	COG2197	response regulator
EXD81_RS08415	COG1307	EDD domain protein, DegV family
EXD81_RS08420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXD81_RS08430	COG1040	competence protein
EXD81_RS08445	COG3418	PFAM FlgN family protein
EXD81_RS08450	COG4786	Flagellar basal body rod
EXD81_RS08450	COG1256	bacterial-type flagellum assembly
EXD81_RS08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXD81_RS08475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXD81_RS08480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EXD81_RS08485	COG1516	flagellar protein fliS
EXD81_RS08500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXD81_RS08525	COG2884	Cell division ATP-binding protein ftsE
EXD81_RS08565	COG2814	Major facilitator Superfamily
EXD81_RS08570	COG1309	transcriptional regulator
EXD81_RS08575	COG0574	Belongs to the PEP-utilizing enzyme family
EXD81_RS08575	COG3848	Pyruvate phosphate dikinase
EXD81_RS08580	COG4897	Protein conserved in bacteria
EXD81_RS08590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXD81_RS08605	COG3595	metallopeptidase activity
EXD81_RS08610	COG1983	PspC domain protein
EXD81_RS08615	COG1950	PFAM Membrane protein of
EXD81_RS08625	COG1309	transcriptional regulator
EXD81_RS08630	COG2188	Transcriptional regulator
EXD81_RS08660	COG0110	maltose O-acetyltransferase activity
EXD81_RS08665	COG4990	cell redox homeostasis
EXD81_RS08680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EXD81_RS08705	COG0140	phosphoribosyl-ATP diphosphatase activity
EXD81_RS08705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EXD81_RS08710	COG1132	(ABC) transporter
EXD81_RS08715	COG0745	RESPONSE REGULATOR receiver
EXD81_RS08720	COG5002	protein histidine kinase activity
EXD81_RS08725	COG0457	Tetratricopeptide repeat
EXD81_RS08735	COG0492	ferredoxin-NADP+ reductase activity
EXD81_RS08750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXD81_RS08760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS08765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXD81_RS08770	COG4290	ribonuclease
EXD81_RS08775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXD81_RS08785	COG0288	reversible hydration of carbon dioxide
EXD81_RS08790	COG0659	secondary active sulfate transmembrane transporter activity
EXD81_RS08800	COG1611	Belongs to the LOG family
EXD81_RS08805	COG1609	Transcriptional regulator
EXD81_RS08810	COG0366	Alpha amylase catalytic
EXD81_RS08815	COG2182	Extracellular solute-binding protein
EXD81_RS08820	COG1175	transmembrane transport
EXD81_RS08825	COG3833	ABC-type maltose transport systems, permease component
EXD81_RS08830	COG5521	maltodextrose utilization protein MalA
EXD81_RS08835	COG1554	hydrolase, family 65, central catalytic
EXD81_RS08845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXD81_RS08855	COG1609	Transcriptional regulator
EXD81_RS08860	COG2223	nitrite transmembrane transporter activity
EXD81_RS08910	COG3479	Phenolic acid decarboxylase
EXD81_RS08915	COG0456	acetyltransferase
EXD81_RS08920	COG2364	Membrane
EXD81_RS08925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXD81_RS08930	COG2272	Belongs to the type-B carboxylesterase lipase family
EXD81_RS08935	COG1396	sequence-specific DNA binding
EXD81_RS08945	COG0489	protein tyrosine kinase activity
EXD81_RS08950	COG1086	Polysaccharide biosynthesis protein
EXD81_RS08955	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS08960	COG1215	transferase activity, transferring glycosyl groups
EXD81_RS08965	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS08975	COG1216	Glycosyl transferase, family 2
EXD81_RS08980	COG5039	Polysaccharide pyruvyl transferase
EXD81_RS08995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXD81_RS09000	COG0110	maltose O-acetyltransferase activity
EXD81_RS09005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_RS09010	COG5039	Polysaccharide pyruvyl transferase
EXD81_RS09020	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXD81_RS09025	COG1620	l-lactate permease
EXD81_RS09030	COG2186	Transcriptional regulator
EXD81_RS09035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_RS09060	COG1070	Carbohydrate kinase
EXD81_RS09065	COG1737	Transcriptional regulator
EXD81_RS09075	COG0697	spore germination
EXD81_RS09090	COG1609	Transcriptional regulator
EXD81_RS09100	COG2390	Transcriptional regulator
EXD81_RS09105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXD81_RS09145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_RS09150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXD81_RS09170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_RS09195	COG3064	Membrane
EXD81_RS09200	COG2095	MarC family integral membrane protein
EXD81_RS09205	COG1510	regulation of RNA biosynthetic process
EXD81_RS09210	COG0517	IMP dehydrogenase activity
EXD81_RS09210	COG1125	glycine betaine transport
EXD81_RS09215	COG1174	glycine betaine transport
EXD81_RS09220	COG1732	Glycine betaine
EXD81_RS09225	COG1174	glycine betaine transport
EXD81_RS09230	COG1510	regulation of RNA biosynthetic process
EXD81_RS09235	COG1125	glycine betaine transport
EXD81_RS09235	COG0517	IMP dehydrogenase activity
EXD81_RS09240	COG1174	glycine betaine transport
EXD81_RS09245	COG1732	Glycine betaine
EXD81_RS09250	COG1174	glycine betaine transport
EXD81_RS09255	COG1131	(ABC) transporter
EXD81_RS09280	COG1733	regulation of RNA biosynthetic process
EXD81_RS09285	COG1396	sequence-specific DNA binding
EXD81_RS09290	COG1396	sequence-specific DNA binding
EXD81_RS09295	COG1476	TRANSCRIPTIONal
EXD81_RS09300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXD81_RS09305	COG1647	Serine aminopeptidase, S33
EXD81_RS09310	COG0557	exoribonuclease II activity
EXD81_RS09325	COG2732	(Barnase) inhibitor
EXD81_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS09335	COG0583	DNA-binding transcription factor activity
EXD81_RS09340	COG0454	-acetyltransferase
EXD81_RS09345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_RS09360	COG0765	amino acid transport
EXD81_RS09365	COG1126	abc transporter atp-binding protein
EXD81_RS09370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_RS09375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EXD81_RS09380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_RS09390	COG0673	inositol 2-dehydrogenase activity
EXD81_RS09395	COG1937	Protein conserved in bacteria
EXD81_RS09400	COG2608	mercury ion transmembrane transporter activity
EXD81_RS09415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXD81_RS09420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXD81_RS09430	COG2860	membrane
EXD81_RS09440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EXD81_RS09465	COG0656	L-ascorbic acid biosynthetic process
EXD81_RS09470	COG0842	Transport permease protein
EXD81_RS09480	COG1131	(ABC) transporter
EXD81_RS09485	COG3850	Histidine kinase
EXD81_RS09490	COG2197	response regulator
EXD81_RS09495	COG4149	molybdate abc transporter
EXD81_RS09500	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXD81_RS09505	COG1910	domain protein
EXD81_RS09515	COG1988	membrane-bound metal-dependent
EXD81_RS09530	COG0531	amino acid
EXD81_RS09535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_RS09540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_RS09550	COG1120	ATPase activity
EXD81_RS09560	COG2140	Oxalate decarboxylase
EXD81_RS09570	COG1191	sigma factor activity
EXD81_RS09580	COG0745	RESPONSE REGULATOR receiver
EXD81_RS09590	COG3386	PFAM SMP-30 Gluconolaconase
EXD81_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS09600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_RS09605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_RS09610	COG1120	ATPase activity
EXD81_RS09615	COG2096	Adenosyltransferase
EXD81_RS09620	COG2814	Major facilitator Superfamily
EXD81_RS09625	COG4758	membrane
EXD81_RS09630	COG1842	Phage shock protein A
EXD81_RS09635	COG3595	metallopeptidase activity
EXD81_RS09640	COG4758	membrane
EXD81_RS09645	COG4585	Histidine kinase
EXD81_RS09650	COG2197	response regulator
EXD81_RS09660	COG0814	amino acid
EXD81_RS09665	COG0697	spore germination
EXD81_RS09680	COG1309	transcriptional regulator
EXD81_RS09690	COG2205	protein histidine kinase activity
EXD81_RS09690	COG2770	Histidine kinase
EXD81_RS09695	COG0745	RESPONSE REGULATOR receiver
EXD81_RS09710	COG0783	Belongs to the Dps family
EXD81_RS09730	COG1120	ATPase activity
EXD81_RS09750	COG0583	DNA-binding transcription factor activity
EXD81_RS09760	COG1846	Transcriptional regulator
EXD81_RS09765	COG5577	PFAM Coat F domain
EXD81_RS09790	COG0183	Belongs to the thiolase family
EXD81_RS09795	COG1960	acyl-CoA dehydrogenase activity
EXD81_RS09800	COG1393	Belongs to the ArsC family
EXD81_RS09820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXD81_RS09835	COG2011	ABC-type metal ion transport system permease component
EXD81_RS09840	COG1464	Belongs to the NlpA lipoprotein family
EXD81_RS09845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXD81_RS09855	COG0396	ATPase activity
EXD81_RS09860	COG0719	Fe-S assembly protein
EXD81_RS09865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXD81_RS09870	COG0822	iron-sulfur transferase activity
EXD81_RS09875	COG0719	Fe-S assembly protein
EXD81_RS09880	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS09895	COG2226	methyltransferase
EXD81_RS09900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXD81_RS09905	COG0322	excinuclease ABC activity
EXD81_RS09915	COG2222	sugar isomerase
EXD81_RS09925	COG1175	transmembrane transport
EXD81_RS09930	COG0395	ABC-type sugar transport system, permease component
EXD81_RS09935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXD81_RS09940	COG2188	Transcriptional regulator
EXD81_RS09950	COG2356	endonuclease I
EXD81_RS09955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_RS09960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXD81_RS09965	COG2814	Major facilitator Superfamily
EXD81_RS09970	COG2369	cell adhesion
EXD81_RS09990	COG2508	Transcriptional regulator
EXD81_RS10005	COG1801	Protein of unknown function DUF72
EXD81_RS10015	COG0737	Belongs to the 5'-nucleotidase family
EXD81_RS10025	COG0739	heme binding
EXD81_RS10040	COG4470	Protein conserved in bacteria
EXD81_RS10045	COG2445	Protein of unknown function DUF86
EXD81_RS10050	COG0647	UMP catabolic process
EXD81_RS10060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXD81_RS10065	COG0460	homoserine dehydrogenase
EXD81_RS10070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EXD81_RS10080	COG1506	peptidase
EXD81_RS10080	COG4946	Tricorn protease homolog
EXD81_RS10080	COG0823	Involved in the tonB-independent uptake of proteins
EXD81_RS10085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXD81_RS10090	COG4837	Protein of unknown function (DUF1462)
EXD81_RS10095	COG1252	NADH dehydrogenase
EXD81_RS10115	COG0316	Belongs to the HesB IscA family
EXD81_RS10175	COG1252	NADH dehydrogenase
EXD81_RS10190	COG3584	3D domain protein
EXD81_RS10205	COG2056	Na+-H+ antiporter family
EXD81_RS10215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXD81_RS10220	COG2819	hydrolase of the alpha beta superfamily
EXD81_RS10225	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS10230	COG1169	isochorismate synthase
EXD81_RS10235	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXD81_RS10240	COG1535	isochorismatase
EXD81_RS10240	COG3433	isochorismatase activity
EXD81_RS10250	COG3251	PFAM MbtH domain protein
EXD81_RS10255	COG5634	Uncharacterized conserved protein (DUF2278)
EXD81_RS10260	COG0686	Belongs to the AlaDH PNT family
EXD81_RS10265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXD81_RS10265	COG2508	Transcriptional regulator
EXD81_RS10270	COG4842	Belongs to the WXG100 family
EXD81_RS10275	COG5417	Belongs to the EsaB family
EXD81_RS10285	COG1674	ftsk spoiiie
EXD81_RS10285	COG0433	COG0433 Predicted ATPase
EXD81_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS10305	COG1418	mRNA catabolic process
EXD81_RS10330	COG5506	Protein of unknown function (DUF1694)
EXD81_RS10335	COG1335	isochorismatase
EXD81_RS10380	COG2197	response regulator
EXD81_RS10385	COG2050	protein possibly involved in aromatic compounds catabolism
EXD81_RS10390	COG1320	monovalent cation:proton antiporter activity
EXD81_RS10395	COG2212	antiporter activity
EXD81_RS10400	COG1863	multisubunit Na H antiporter MnhE subunit
EXD81_RS10405	COG0651	ATP synthesis coupled electron transport
EXD81_RS10415	COG2111	Na H antiporter
EXD81_RS10420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXD81_RS10420	COG2111	Na H antiporter
EXD81_RS10430	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXD81_RS10435	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXD81_RS10440	COG3845	ABC transporter
EXD81_RS10445	COG1744	ABC transporter substrate-binding protein PnrA-like
EXD81_RS10450	COG4565	transcriptional regulatory protein
EXD81_RS10455	COG3290	protein histidine kinase activity
EXD81_RS10465	COG3011	Protein conserved in bacteria
EXD81_RS10470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_RS10480	COG5018	Exonuclease
EXD81_RS10505	COG2267	carboxylic ester hydrolase activity
EXD81_RS10510	COG1522	sequence-specific DNA binding
EXD81_RS10515	COG0436	Aminotransferase
EXD81_RS10520	COG1098	S1 RNA binding domain
EXD81_RS10525	COG2155	Conserved Protein
EXD81_RS10530	COG1979	alcohol dehydrogenase
EXD81_RS10570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXD81_RS10585	COG2738	Putative neutral zinc metallopeptidase
EXD81_RS10590	COG1253	flavin adenine dinucleotide binding
EXD81_RS10595	COG0366	Alpha amylase catalytic
EXD81_RS10600	COG0432	Pfam Uncharacterised protein family UPF0047
EXD81_RS10605	COG2070	2-Nitropropane dioxygenase
EXD81_RS10625	COG0840	transmembrane signaling receptor activity
EXD81_RS10630	COG0840	transmembrane signaling receptor activity
EXD81_RS10635	COG0840	transmembrane signaling receptor activity
EXD81_RS10640	COG0693	protein deglycase activity
EXD81_RS10645	COG0673	inositol 2-dehydrogenase activity
EXD81_RS10650	COG0628	permease
EXD81_RS10665	COG0582	viral genome integration into host DNA
EXD81_RS10670	COG2856	Zn peptidase
EXD81_RS10680	COG3620	sequence-specific DNA binding
EXD81_RS10735	COG3935	DnaD domain protein
EXD81_RS10740	COG1484	DNA-dependent DNA replication
EXD81_RS10745	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EXD81_RS10795	COG1595	DNA-templated transcription, initiation
EXD81_RS10945	COG1388	LysM domain
EXD81_RS10945	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS10945	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS10995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EXD81_RS10995	COG1017	nitric oxide dioxygenase activity
EXD81_RS11000	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXD81_RS11005	COG0569	domain protein
EXD81_RS11015	COG1510	regulation of RNA biosynthetic process
EXD81_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_RS11035	COG2318	DinB family
EXD81_RS11040	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXD81_RS11050	COG3859	Proton-coupled thiamine transporter YuaJ
EXD81_RS11175	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EXD81_RS11180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_RS11200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXD81_RS11225	COG1294	oxidase, subunit
EXD81_RS11230	COG1271	oxidase subunit
EXD81_RS11240	COG0288	reversible hydration of carbon dioxide
EXD81_RS11265	COG0783	Belongs to the Dps family
EXD81_RS11275	COG0494	nUDIX hydrolase
EXD81_RS11280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXD81_RS11285	COG1116	anion transmembrane transporter activity
EXD81_RS11290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXD81_RS11315	COG0367	asparagine synthase
EXD81_RS11330	COG2267	carboxylic ester hydrolase activity
EXD81_RS11345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXD81_RS11360	COG1725	Transcriptional regulator
EXD81_RS11365	COG1131	(ABC) transporter
EXD81_RS11380	COG1136	(ABC) transporter
EXD81_RS11385	COG0577	efflux transmembrane transporter activity
EXD81_RS11390	COG0745	RESPONSE REGULATOR receiver
EXD81_RS11395	COG2205	protein histidine kinase activity
EXD81_RS11400	COG1136	(ABC) transporter
EXD81_RS11405	COG0577	efflux transmembrane transporter activity
EXD81_RS11415	COG2814	Major facilitator Superfamily
EXD81_RS11420	COG2202	Pas domain
EXD81_RS11420	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS11435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_RS11445	COG1486	melibiose metabolic process
EXD81_RS11450	COG1175	transmembrane transport
EXD81_RS11455	COG1653	transport
EXD81_RS11460	COG1609	Transcriptional regulator
EXD81_RS11470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXD81_RS11480	COG2244	polysaccharide biosynthetic process
EXD81_RS11485	COG1187	pseudouridine synthase activity
EXD81_RS11490	COG1349	DNA-binding transcription factor activity
EXD81_RS11495	COG1131	(ABC) transporter
EXD81_RS11500	COG4473	ABC transporter
EXD81_RS11515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_RS11520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXD81_RS11530	COG1597	lipid kinase activity
EXD81_RS11535	COG0510	thiamine kinase activity
EXD81_RS11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS11555	COG0281	malic enzyme
EXD81_RS11560	COG5584	Small secreted protein
EXD81_RS11565	COG1363	Peptidase, m42
EXD81_RS11575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXD81_RS11590	COG1674	ftsk spoiiie
EXD81_RS11600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EXD81_RS11610	COG3118	belongs to the thioredoxin family
EXD81_RS11615	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXD81_RS11615	COG1605	Chorismate mutase
EXD81_RS11620	COG1609	Transcriptional regulator
EXD81_RS11625	COG1609	Transcriptional regulator
EXD81_RS11630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXD81_RS11635	COG1360	Flagellar Motor Protein
EXD81_RS11640	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXD81_RS11645	COG0517	IMP dehydrogenase activity
EXD81_RS11650	COG0454	-acetyltransferase
EXD81_RS11655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXD81_RS11675	COG1378	Sugar-specific transcriptional regulator TrmB
EXD81_RS11695	COG0693	protein deglycase activity
EXD81_RS11705	COG1017	nitric oxide dioxygenase activity
EXD81_RS11705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EXD81_RS11730	COG1595	DNA-templated transcription, initiation
EXD81_RS11770	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_RS11790	COG1956	GAF domain-containing protein
EXD81_RS11795	COG1309	transcriptional regulator
EXD81_RS11810	COG1114	Component of the transport system for branched-chain amino acids
EXD81_RS11815	COG1104	cysteine desulfurase activity
EXD81_RS11830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXD81_RS11835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXD81_RS11840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EXD81_RS11845	COG0616	signal peptide processing
EXD81_RS11850	COG1714	RDD family
EXD81_RS11865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXD81_RS11870	COG0827	DNA restriction-modification system
EXD81_RS11880	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXD81_RS11940	COG0281	malic enzyme
EXD81_RS11965	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXD81_RS11970	COG0628	permease
EXD81_RS11985	COG0372	Belongs to the citrate synthase family
EXD81_RS11990	COG0538	isocitrate dehydrogenase activity
EXD81_RS12000	COG0745	RESPONSE REGULATOR receiver
EXD81_RS12010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_RS12010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_RS12015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EXD81_RS12020	COG1971	Probably functions as a manganese efflux pump
EXD81_RS12025	COG0237	dephospho-CoA kinase activity
EXD81_RS12030	COG0656	L-ascorbic acid biosynthetic process
EXD81_RS12035	COG2814	Major facilitator Superfamily
EXD81_RS12040	COG1733	regulation of RNA biosynthetic process
EXD81_RS12045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXD81_RS12065	COG1484	DNA-dependent DNA replication
EXD81_RS12070	COG0398	Pfam SNARE associated Golgi protein
EXD81_RS12085	COG1011	Hydrolase
EXD81_RS12090	COG3275	phosphorelay sensor kinase activity
EXD81_RS12095	COG3279	Response regulator of the LytR AlgR family
EXD81_RS12105	COG1346	cytolysis
EXD81_RS12110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EXD81_RS12120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXD81_RS12125	COG3326	Membrane
EXD81_RS12135	COG1363	Peptidase, m42
EXD81_RS12140	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_RS12145	COG2160	L-arabinose isomerase activity
EXD81_RS12155	COG0235	Class ii aldolase
EXD81_RS12170	COG1653	transport
EXD81_RS12175	COG1175	transmembrane transport
EXD81_RS12185	COG3534	alpha-L-arabinofuranosidase
EXD81_RS12190	COG1966	Carbon starvation protein
EXD81_RS12195	COG0247	lactate metabolic process
EXD81_RS12200	COG0277	FAD linked oxidase domain protein
EXD81_RS12205	COG3835	regulator
EXD81_RS12240	COG1286	toxin biosynthetic process
EXD81_RS12245	COG1796	DNA polymerase
EXD81_RS12245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXD81_RS12255	COG3766	membrane
EXD81_RS12265	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_RS12275	COG1024	Enoyl-CoA hydratase
EXD81_RS12280	COG2086	electron transfer activity
EXD81_RS12285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXD81_RS12290	COG3534	alpha-L-arabinofuranosidase
EXD81_RS12295	COG3118	belongs to the thioredoxin family
EXD81_RS12310	COG0527	aspartate kinase activity
EXD81_RS12320	COG2009	succinate dehydrogenase
EXD81_RS12330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXD81_RS12335	COG0824	Thioesterase
EXD81_RS12345	COG2856	Zn peptidase
EXD81_RS12355	COG3620	sequence-specific DNA binding
EXD81_RS12360	COG1476	TRANSCRIPTIONal
EXD81_RS12365	COG3617	BRO family, N-terminal domain
EXD81_RS12395	COG5377	YqaJ viral recombinase family
EXD81_RS12400	COG3723	Recombinational DNA repair protein, rece pathway
EXD81_RS12410	COG1484	DNA-dependent DNA replication
EXD81_RS12515	COG3677	Transposase
EXD81_RS12710	COG0457	Tetratricopeptide repeat
EXD81_RS12725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXD81_RS12730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXD81_RS12735	COG2197	response regulator
EXD81_RS12750	COG5401	PFAM Sporulation and spore germination
EXD81_RS12760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EXD81_RS12765	COG0622	Phosphoesterase
EXD81_RS12795	COG0440	acetolactate synthase activity
EXD81_RS12810	COG0473	3-isopropylmalate dehydrogenase activity
EXD81_RS12825	COG1477	protein flavinylation
EXD81_RS12825	COG0457	Tetratricopeptide repeat
EXD81_RS12845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EXD81_RS12865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXD81_RS12875	COG1587	Uroporphyrinogen-III synthase
EXD81_RS12880	COG0113	porphobilinogen synthase activity
EXD81_RS12890	COG1388	LysM domain
EXD81_RS12905	COG0525	valine-tRNA ligase activity
EXD81_RS12910	COG0285	dihydrofolate synthase activity
EXD81_RS12945	COG1396	sequence-specific DNA binding
EXD81_RS12965	COG3646	Phage regulatory protein
EXD81_RS12965	COG3645	SOS response
EXD81_RS12990	COG0305	Participates in initiation and elongation during chromosome replication
EXD81_RS13015	COG1595	DNA-templated transcription, initiation
EXD81_RS13165	COG4824	toxin secretion phage lysis holin
EXD81_RS13170	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS13170	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS13170	COG1388	LysM domain
EXD81_RS13195	COG1077	Cell shape determining protein MreB Mrl
EXD81_RS13205	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EXD81_RS13215	COG2894	cell division
EXD81_RS13220	COG0739	heme binding
EXD81_RS13235	COG2868	ribosomal protein
EXD81_RS13240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EXD81_RS13245	COG3290	protein histidine kinase activity
EXD81_RS13260	COG0077	Prephenate dehydratase
EXD81_RS13265	COG1827	regulation of RNA biosynthetic process
EXD81_RS13270	COG1104	cysteine desulfurase activity
EXD81_RS13275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXD81_RS13290	COG1388	LysM domain
EXD81_RS13335	COG1862	Preprotein translocase
EXD81_RS13360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXD81_RS13360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXD81_RS13365	COG0490	domain, Protein
EXD81_RS13370	COG5416	Lipopolysaccharide assembly protein A domain
EXD81_RS13385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXD81_RS13395	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS13395	COG4991	sh3 domain protein
EXD81_RS13395	COG3103	Sh3 type 3 domain protein
EXD81_RS13415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXD81_RS13430	COG1104	cysteine desulfurase activity
EXD81_RS13440	COG0457	Tetratricopeptide repeat
EXD81_RS13445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXD81_RS13450	COG3881	PFAM PRC-barrel domain
EXD81_RS13465	COG0765	amino acid transport
EXD81_RS13470	COG0765	amino acid transport
EXD81_RS13480	COG1126	abc transporter atp-binding protein
EXD81_RS13515	COG4122	O-methyltransferase activity
EXD81_RS13520	COG0826	peptidase U32
EXD81_RS13540	COG0768	penicillin binding
EXD81_RS13565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_RS13570	COG0626	cystathionine gamma-synthase activity
EXD81_RS13580	COG2427	Protein of unknown function (DUF1641)
EXD81_RS13585	COG3383	formate dehydrogenase (NAD+) activity
EXD81_RS13590	COG5609	conserved protein (DUF2294)
EXD81_RS13610	COG2226	methyltransferase
EXD81_RS13615	COG1309	transcriptional regulator
EXD81_RS13620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EXD81_RS13620	COG2124	cytochrome p450
EXD81_RS13630	COG0583	DNA-binding transcription factor activity
EXD81_RS13635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXD81_RS13645	COG3711	transcriptional antiterminator
EXD81_RS13645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS13650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS13650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_RS13650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_RS13655	COG1482	cell wall glycoprotein biosynthetic process
EXD81_RS13680	COG2318	DinB family
EXD81_RS13700	COG0563	adenylate kinase activity
EXD81_RS13750	COG0398	Pfam SNARE associated Golgi protein
EXD81_RS13760	COG2755	lipolytic protein G-D-S-L family
EXD81_RS13770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXD81_RS13775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXD81_RS13780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXD81_RS13785	COG1534	Rna-binding protein
EXD81_RS13795	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXD81_RS13800	COG0799	negative regulation of ribosome biogenesis
EXD81_RS13805	COG2226	methyltransferase
EXD81_RS13810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXD81_RS13815	COG1596	polysaccharide export
EXD81_RS13815	COG1555	photosystem II stabilization
EXD81_RS13820	COG2131	deaminase
EXD81_RS13865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXD81_RS13895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXD81_RS13900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXD81_RS13905	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXD81_RS13915	COG1610	YqeY-like protein
EXD81_RS13920	COG1030	water channel activity
EXD81_RS13925	COG4864	UPF0365 protein
EXD81_RS13945	COG1702	phosphate starvation-inducible protein PhoH
EXD81_RS13950	COG1480	7TM receptor with intracellular HD hydrolase
EXD81_RS13960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXD81_RS13965	COG0295	cytidine deaminase activity
EXD81_RS13990	COG0751	glycine-tRNA ligase activity
EXD81_RS13995	COG0517	IMP dehydrogenase activity
EXD81_RS14010	COG0358	DNA primase activity
EXD81_RS14015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXD81_RS14020	COG2010	Cytochrome c
EXD81_RS14025	COG2384	SAM-dependent methyltransferase
EXD81_RS14030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXD81_RS14060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS14065	COG0735	belongs to the Fur family
EXD81_RS14070	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EXD81_RS14075	COG4709	membrane
EXD81_RS14085	COG1388	LysM domain
EXD81_RS14090	COG5521	maltodextrose utilization protein MalA
EXD81_RS14095	COG2839	Protein conserved in bacteria
EXD81_RS14100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXD81_RS14105	COG0477	Major facilitator Superfamily
EXD81_RS14110	COG0768	penicillin binding
EXD81_RS14120	COG0573	inorganic phosphate transmembrane transporter activity
EXD81_RS14125	COG0581	inorganic phosphate transmembrane transporter activity
EXD81_RS14130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXD81_RS14140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXD81_RS14155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXD81_RS14165	COG1757	Na H antiporter
EXD81_RS14170	COG4483	Protein conserved in bacteria
EXD81_RS14175	COG1940	carbohydrate kinase activity
EXD81_RS14190	COG0011	TIGRFAM Protein of
EXD81_RS14200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS14210	COG1393	Belongs to the ArsC family
EXD81_RS14220	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS14230	COG0598	Magnesium transport protein CorA
EXD81_RS14245	COG4537	Required for transformation and DNA binding
EXD81_RS14250	COG4970	Tfp pilus assembly protein FimT
EXD81_RS14260	COG4940	Competence protein ComGF
EXD81_RS14285	COG0681	Belongs to the peptidase S26 family
EXD81_RS14295	COG1396	sequence-specific DNA binding
EXD81_RS14330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_RS14355	COG3872	metal-dependent enzyme
EXD81_RS14365	COG0006	proline dipeptidase activity
EXD81_RS14380	COG3854	ATPases associated with a variety of cellular activities
EXD81_RS14430	COG1302	Protein conserved in bacteria
EXD81_RS14445	COG1570	exodeoxyribonuclease VII activity
EXD81_RS14455	COG0142	geranyltranstransferase activity
EXD81_RS14465	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXD81_RS14485	COG0745	RESPONSE REGULATOR receiver
EXD81_RS14495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXD81_RS14510	COG1902	pentaerythritol trinitrate reductase activity
EXD81_RS14530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS14540	COG0183	Belongs to the thiolase family
EXD81_RS14545	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXD81_RS14555	COG0372	Belongs to the citrate synthase family
EXD81_RS14560	COG2079	MmgE PrpD family protein
EXD81_RS14565	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXD81_RS14575	COG3829	transcription factor binding
EXD81_RS14575	COG3290	protein histidine kinase activity
EXD81_RS14580	COG0280	phosphate acetyltransferase
EXD81_RS14585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_RS14595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXD81_RS14600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_RS14605	COG0022	dehydrogenase e1 component
EXD81_RS14610	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_RS14615	COG1597	lipid kinase activity
EXD81_RS14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_RS14630	COG0765	amino acid transport
EXD81_RS14635	COG1126	abc transporter atp-binding protein
EXD81_RS14640	COG4129	membrane
EXD81_RS14645	COG1376	ErfK ybiS ycfS ynhG family protein
EXD81_RS14665	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXD81_RS14685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EXD81_RS14690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXD81_RS14705	COG0596	Alpha beta hydrolase
EXD81_RS14730	COG0250	Participates in transcription elongation, termination and antitermination
EXD81_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS14770	COG0300	oxidoreductase activity
EXD81_RS14770	COG3321	synthase
EXD81_RS14770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS14770	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS14800	COG2124	cytochrome p450
EXD81_RS14810	COG1024	Enoyl-CoA hydratase
EXD81_RS14815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXD81_RS14830	COG3048	D-serine ammonia-lyase activity
EXD81_RS14840	COG0346	lactoylglutathione lyase activity
EXD81_RS14865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXD81_RS14870	COG0456	acetyltransferase
EXD81_RS14875	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_RS14880	COG0456	acetyltransferase
EXD81_RS14880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXD81_RS14885	COG4918	Iron-sulphur cluster biosynthesis
EXD81_RS14895	COG1073	alpha beta
EXD81_RS14905	COG0667	Aldo Keto reductase
EXD81_RS14920	COG1379	DNA repair
EXD81_RS14925	COG1396	sequence-specific DNA binding
EXD81_RS14930	COG0252	asparaginase activity
EXD81_RS14935	COG1027	Aspartate ammonia-lyase
EXD81_RS14960	COG1300	Membrane
EXD81_RS14965	COG0735	belongs to the Fur family
EXD81_RS14980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXD81_RS14985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EXD81_RS14995	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS15040	COG0697	spore germination
EXD81_RS15050	COG4086	secreted protein
EXD81_RS15055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXD81_RS15065	COG0681	Belongs to the peptidase S26 family
EXD81_RS15075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXD81_RS15075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXD81_RS15080	COG0307	riboflavin synthase, alpha
EXD81_RS15095	COG0456	acetyltransferase
EXD81_RS15130	COG2715	membrane protein required for spore maturation
EXD81_RS15135	COG0700	Nucleoside recognition
EXD81_RS15140	COG1187	pseudouridine synthase activity
EXD81_RS15145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS15150	COG1333	cytochrome c biogenesis protein
EXD81_RS15155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXD81_RS15160	COG0745	RESPONSE REGULATOR receiver
EXD81_RS15170	COG1595	DNA-templated transcription, initiation
EXD81_RS15195	COG1141	Ferredoxin
EXD81_RS15210	COG1266	CAAX protease self-immunity
EXD81_RS15225	COG1408	metallophosphoesterase
EXD81_RS15230	COG4862	establishment of competence for transformation
EXD81_RS15235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_RS15240	COG0492	ferredoxin-NADP+ reductase activity
EXD81_RS15250	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS15250	COG3773	Cell wall hydrolase
EXD81_RS15260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EXD81_RS15310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXD81_RS15315	COG0776	regulation of translation
EXD81_RS15330	COG0142	geranyltranstransferase activity
EXD81_RS15340	COG0142	geranyltranstransferase activity
EXD81_RS15345	COG0105	UTP biosynthetic process
EXD81_RS15350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXD81_RS15365	COG4401	Chorismate mutase type I
EXD81_RS15370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXD81_RS15415	COG0457	Tetratricopeptide repeat
EXD81_RS15435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXD81_RS15445	COG4347	Protein of unknown function (DUF1405)
EXD81_RS15455	COG2140	Oxalate decarboxylase
EXD81_RS15460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS15465	COG1694	Mazg nucleotide pyrophosphohydrolase
EXD81_RS15480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_RS15485	COG0438	transferase activity, transferring glycosyl groups
EXD81_RS15530	COG0436	Aminotransferase
EXD81_RS15540	COG3935	DnaD domain protein
EXD81_RS15545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXD81_RS15555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_RS15555	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXD81_RS15595	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_RS15600	COG2190	(PTS) system
EXD81_RS15605	COG1205	dead DEAH box helicase
EXD81_RS15605	COG1111	helicase
EXD81_RS15640	COG0116	Belongs to the methyltransferase superfamily
EXD81_RS15655	COG1199	ATP-dependent helicase activity
EXD81_RS15670	COG2233	PERMEase
EXD81_RS15680	COG1335	isochorismatase
EXD81_RS15730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_RS15740	COG0328	RNA-DNA hybrid ribonuclease activity
EXD81_RS15745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EXD81_RS15750	COG0328	RNA-DNA hybrid ribonuclease activity
EXD81_RS15770	COG1278	Cold shock
EXD81_RS15780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXD81_RS15790	COG0386	Belongs to the glutathione peroxidase family
EXD81_RS15795	COG1418	mRNA catabolic process
EXD81_RS15800	COG1413	lyase activity
EXD81_RS15815	COG2136	Putative SAM-dependent methyltransferase
EXD81_RS15815	COG2521	methyltransferase
EXD81_RS15830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXD81_RS15835	COG0204	Acyl-transferase
EXD81_RS15840	COG1272	protein, Hemolysin III
EXD81_RS15845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXD81_RS15850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXD81_RS15865	COG2755	lipolytic protein G-D-S-L family
EXD81_RS15870	COG4698	Protein conserved in bacteria
EXD81_RS15890	COG1086	Polysaccharide biosynthesis protein
EXD81_RS15900	COG4641	Protein conserved in bacteria
EXD81_RS15915	COG0463	Glycosyl transferase, family 2
EXD81_RS15920	COG0456	acetyltransferase
EXD81_RS15930	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EXD81_RS15935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_RS15940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXD81_RS15945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXD81_RS15950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_RS15955	COG0456	acetyltransferase
EXD81_RS15960	COG1509	lysine 2,3-aminomutase activity
EXD81_RS15990	COG0671	phosphoesterase, PA-phosphatase related
EXD81_RS16020	COG2226	methyltransferase
EXD81_RS16025	COG0793	Belongs to the peptidase S41A family
EXD81_RS16025	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS16060	COG0346	lactoylglutathione lyase activity
EXD81_RS16065	COG0400	carboxylic ester hydrolase activity
EXD81_RS16070	COG0778	Nitroreductase
EXD81_RS16075	COG1733	regulation of RNA biosynthetic process
EXD81_RS16085	COG1942	4-Oxalocrotonate Tautomerase
EXD81_RS16110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_RS16115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_RS16120	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS16125	COG0534	Mate efflux family protein
EXD81_RS16130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXD81_RS16135	COG1819	glycosyl
EXD81_RS16145	COG2032	superoxide dismutase activity
EXD81_RS16150	COG0714	Associated with various cellular activities
EXD81_RS16165	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_RS16170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS16175	COG0385	Bile acid
EXD81_RS16190	COG1657	PFAM Prenyltransferase squalene oxidase
EXD81_RS16240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_RS16245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EXD81_RS16255	COG0514	ATP-dependent DNA helicase (RecQ)
EXD81_RS16260	COG1388	LysM domain
EXD81_RS16260	COG3584	3D domain protein
EXD81_RS16270	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXD81_RS16290	COG0741	lytic transglycosylase activity
EXD81_RS16295	COG0640	Transcriptional regulator
EXD81_RS16305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_RS16310	COG1309	transcriptional regulator
EXD81_RS16315	COG2207	Transcriptional regulator
EXD81_RS16315	COG0662	Cupin 2, conserved barrel domain protein
EXD81_RS16320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXD81_RS16360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXD81_RS16365	COG1070	Carbohydrate kinase
EXD81_RS16380	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EXD81_RS16385	COG0300	oxidoreductase activity
EXD81_RS16410	COG0583	DNA-binding transcription factor activity
EXD81_RS16420	COG0493	'glutamate synthase
EXD81_RS16430	COG0604	alcohol dehydrogenase
EXD81_RS16440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXD81_RS16445	COG0640	Transcriptional regulator
EXD81_RS16450	COG2814	Major facilitator Superfamily
EXD81_RS16455	COG0405	Gamma-glutamyltransferase
EXD81_RS16460	COG0166	Belongs to the GPI family
EXD81_RS16465	COG0582	viral genome integration into host DNA
EXD81_RS16480	COG0534	Mate efflux family protein
EXD81_RS16485	COG2017	converts alpha-aldose to the beta-anomer
EXD81_RS16490	COG2027	D-alanyl-D-alanine carboxypeptidase
EXD81_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS16520	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EXD81_RS16520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS16530	COG1649	PFAM Uncharacterised BCR, COG1649
EXD81_RS16535	COG1960	acyl-CoA dehydrogenase activity
EXD81_RS16540	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_RS16545	COG0439	Biotin carboxylase
EXD81_RS16550	COG0511	ligase activity, forming carbon-carbon bonds
EXD81_RS16555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXD81_RS16560	COG1024	Enoyl-CoA hydratase
EXD81_RS16565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXD81_RS16570	COG0586	Pfam SNARE associated Golgi protein
EXD81_RS16575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXD81_RS16580	COG2246	polysaccharide biosynthetic process
EXD81_RS16590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_RS16615	COG2610	gluconate transmembrane transporter activity
EXD81_RS16620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXD81_RS16625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXD81_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS16655	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_RS16670	COG2205	protein histidine kinase activity
EXD81_RS16700	COG1136	(ABC) transporter
EXD81_RS16700	COG0577	efflux transmembrane transporter activity
EXD81_RS16730	COG2271	Major facilitator Superfamily
EXD81_RS16735	COG1609	Transcriptional regulator
EXD81_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS16745	COG1312	Catalyzes the dehydration of D-mannonate
EXD81_RS16750	COG0800	Aldolase
EXD81_RS16755	COG1063	alcohol dehydrogenase
EXD81_RS16765	COG1115	amino acid carrier protein
EXD81_RS16775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXD81_RS16785	COG1832	CoA-binding protein
EXD81_RS16795	COG4841	protein insertion into membrane
EXD81_RS16805	COG0824	Thioesterase
EXD81_RS16825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS16830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXD81_RS16845	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_RS16855	COG4846	Membrane protein involved in cytochrome C biogenesis
EXD81_RS16860	COG2201	protein-glutamate methylesterase activity
EXD81_RS16865	COG0785	Cytochrome C biogenesis protein
EXD81_RS16895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXD81_RS16925	COG4195	phage-related replication protein
EXD81_RS16935	COG0756	dUTP diphosphatase activity
EXD81_RS16940	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_RS16965	COG3397	chitin binding
EXD81_RS17000	COG0456	acetyltransferase
EXD81_RS17020	COG1064	alcohol dehydrogenase
EXD81_RS17055	COG0574	Belongs to the PEP-utilizing enzyme family
EXD81_RS17055	COG3848	Pyruvate phosphate dikinase
EXD81_RS17060	COG1070	Carbohydrate kinase
EXD81_RS17080	COG2211	Major facilitator Superfamily
EXD81_RS17090	COG0174	glutamine synthetase
EXD81_RS17100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXD81_RS17105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXD81_RS17110	COG0464	growth
EXD81_RS17120	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS17125	COG4112	unkown
EXD81_RS17175	COG2076	Multidrug Resistance protein
EXD81_RS17180	COG2076	Multidrug Resistance protein
EXD81_RS17185	COG1764	response to oxidative stress
EXD81_RS17190	COG4195	phage-related replication protein
EXD81_RS17200	COG1404	Belongs to the peptidase S8 family
EXD81_RS17220	COG2124	cytochrome p450
EXD81_RS17225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EXD81_RS17225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXD81_RS17225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXD81_RS17225	COG3321	synthase
EXD81_RS17255	COG1024	Enoyl-CoA hydratase
EXD81_RS17260	COG3425	synthase
EXD81_RS17265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXD81_RS17335	COG2359	stage V sporulation protein S
EXD81_RS17340	COG1692	metallophosphoesterase
EXD81_RS17350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_RS17365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXD81_RS17370	COG1426	Protein conserved in bacteria
EXD81_RS17385	COG0300	oxidoreductase activity
EXD81_RS17395	COG0612	Peptidase, M16
EXD81_RS17405	COG1846	Transcriptional regulator
EXD81_RS17410	COG2814	Major facilitator Superfamily
EXD81_RS17415	COG2188	Transcriptional regulator
EXD81_RS17430	COG0740	serine-type endopeptidase activity
EXD81_RS17435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXD81_RS17445	COG0527	aspartate kinase activity
EXD81_RS17450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXD81_RS17460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXD81_RS17465	COG1873	PFAM PRC-barrel domain
EXD81_RS17470	COG0612	Peptidase, M16
EXD81_RS17475	COG0726	polysaccharide deacetylase
EXD81_RS17490	COG0196	riboflavin kinase activity
EXD81_RS17505	COG1550	Protein conserved in bacteria
EXD81_RS17515	COG1358	cellular component organization or biogenesis
EXD81_RS17520	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXD81_RS17525	COG0195	Participates in both transcription termination and antitermination
EXD81_RS17545	COG0750	zinc metalloprotease
EXD81_RS17560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EXD81_RS17590	COG1191	sigma factor activity
EXD81_RS17600	COG1776	CheC inhibitor of MCP methylation
EXD81_RS17605	COG0835	chemotaxis
EXD81_RS17610	COG0643	Histidine kinase
EXD81_RS17610	COG2198	Histidine kinase
EXD81_RS17615	COG2201	protein-glutamate methylesterase activity
EXD81_RS17620	COG0455	bacterial-type flagellum organization
EXD81_RS17625	COG1419	protein localization to endoplasmic reticulum
EXD81_RS17645	COG1987	bacterial-type flagellum assembly
EXD81_RS17650	COG1338	Plays a role in the flagellum-specific transport system
EXD81_RS17660	COG2201	protein-glutamate methylesterase activity
EXD81_RS17665	COG1776	CheC inhibitor of MCP methylation
EXD81_RS17665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXD81_RS17675	COG1580	Controls the rotational direction of flagella during chemotaxis
EXD81_RS17680	COG1582	Flagellar protein (FlbD)
EXD81_RS17685	COG4786	Flagellar basal body rod
EXD81_RS17690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EXD81_RS17695	COG3144	bacterial-type flagellum assembly
EXD81_RS17705	COG2882	bacterial-type flagellum organization
EXD81_RS17710	COG1157	protein secretion by the type III secretion system
EXD81_RS17715	COG1317	bacterial-type flagellum organization
EXD81_RS17720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXD81_RS17725	COG1766	The M ring may be actively involved in energy transduction
EXD81_RS17730	COG1677	Flagellar hook-basal body complex protein FliE
EXD81_RS17735	COG1558	bacterial-type flagellum-dependent cell motility
EXD81_RS17740	COG1815	bacterial-type flagellum-dependent cell motility
EXD81_RS17770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXD81_RS17780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXD81_RS17790	COG2257	FlhB HrpN YscU SpaS Family
EXD81_RS17805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXD81_RS17830	COG1837	Belongs to the UPF0109 family
EXD81_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS17880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXD81_RS17900	COG1760	l-serine dehydratase
EXD81_RS17905	COG1760	l-serine dehydratase
EXD81_RS17910	COG1461	Dihydroxyacetone kinase
EXD81_RS17915	COG1302	Protein conserved in bacteria
EXD81_RS17930	COG1564	THIamine pyrophosphokinase
EXD81_RS17935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXD81_RS17945	COG0515	serine threonine protein kinase
EXD81_RS17945	COG2815	serine threonine protein kinase
EXD81_RS17950	COG0631	protein serine/threonine phosphatase activity
EXD81_RS17960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXD81_RS17960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXD81_RS17970	COG0242	peptide deformylase activity
EXD81_RS17980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXD81_RS17990	COG0194	GDP metabolic process
EXD81_RS18000	COG1561	YicC-like family, N-terminal region
EXD81_RS18020	COG1648	precorrin-2 dehydrogenase activity
EXD81_RS18025	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EXD81_RS18030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXD81_RS18045	COG0306	phosphate transporter
EXD81_RS18060	COG0284	orotidine-5'-phosphate decarboxylase activity
EXD81_RS18080	COG0505	Belongs to the CarA family
EXD81_RS18095	COG2233	PERMEase
EXD81_RS18105	COG0564	pseudouridine synthase activity
EXD81_RS18115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_RS18120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXD81_RS18130	COG3599	regulation of cell shape
EXD81_RS18135	COG2302	S4 RNA-binding domain
EXD81_RS18140	COG0762	integral membrane protein
EXD81_RS18150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXD81_RS18155	COG1496	oxidoreductase activity
EXD81_RS18160	COG1873	PFAM PRC-barrel domain
EXD81_RS18165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_RS18175	COG1191	sigma factor activity
EXD81_RS18180	COG1191	sigma factor activity
EXD81_RS18195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXD81_RS18205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXD81_RS18220	COG0772	Belongs to the SEDS family
EXD81_RS18250	COG4839	cell division protein FtsL
EXD81_RS18270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXD81_RS18290	COG1399	metal-binding, possibly nucleic acid-binding protein
EXD81_RS18305	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXD81_RS18310	COG3314	Sporulation integral membrane protein YlbJ
EXD81_RS18320	COG0742	ribosomal rna small subunit methyltransferase
EXD81_RS18330	COG3679	Belongs to the UPF0342 family
EXD81_RS18345	COG2340	Cysteine-rich secretory protein family
EXD81_RS18350	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXD81_RS18360	COG3336	cytochrome c oxidase
EXD81_RS18365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EXD81_RS18370	COG1845	cytochrome c oxidase, subunit III
EXD81_RS18430	COG4896	Protein conserved in bacteria
EXD81_RS18440	COG1217	gtp-binding protein TYPA
EXD81_RS18465	COG3227	Zinc metalloprotease (Elastase)
EXD81_RS18475	COG0483	inositol monophosphate 1-phosphatase activity
EXD81_RS18500	COG1982	Orn Lys Arg decarboxylase major
EXD81_RS18515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS18520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXD81_RS18525	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_RS18530	COG0022	dehydrogenase e1 component
EXD81_RS18535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_RS18540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS18550	COG3321	synthase
EXD81_RS18550	COG0300	oxidoreductase activity
EXD81_RS18550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_RS18600	COG0242	peptide deformylase activity
EXD81_RS18605	COG0561	phosphatase activity
EXD81_RS18615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXD81_RS18625	COG0569	domain protein
EXD81_RS18630	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EXD81_RS18630	COG2105	PFAM AIG2 family protein
EXD81_RS18635	COG3852	Histidine kinase
EXD81_RS18640	COG2002	toxin-antitoxin pair type II binding
EXD81_RS18650	COG1077	Cell shape determining protein MreB Mrl
EXD81_RS18660	COG2309	aminopeptidase activity
EXD81_RS18665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXD81_RS18670	COG0488	(ABC) transporter
EXD81_RS18685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_RS18685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_RS18685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS18695	COG1349	DNA-binding transcription factor activity
EXD81_RS18705	COG1136	(ABC) transporter
EXD81_RS18720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXD81_RS18725	COG0314	molybdopterin synthase activity
EXD81_RS18730	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXD81_RS18740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_RS18760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS18765	COG0668	transmembrane transport
EXD81_RS18785	COG0716	FMN binding
EXD81_RS18800	COG0583	DNA-binding transcription factor activity
EXD81_RS18805	COG0517	IMP dehydrogenase activity
EXD81_RS18815	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXD81_RS18820	COG4703	Protein of unknown function (DUF1797)
EXD81_RS18840	COG1408	metallophosphoesterase
EXD81_RS18845	COG1376	ErfK ybiS ycfS ynhG family protein
EXD81_RS18850	COG2814	Major facilitator Superfamily
EXD81_RS18860	COG0835	chemotaxis
EXD81_RS18860	COG0784	Response regulator, receiver
EXD81_RS18880	COG0768	penicillin binding
EXD81_RS18885	COG2340	Cysteine-rich secretory protein family
EXD81_RS18905	COG2084	Dehydrogenase
EXD81_RS18910	COG0840	transmembrane signaling receptor activity
EXD81_RS18915	COG1533	DNA photolyase activity
EXD81_RS18925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EXD81_RS18930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_RS18935	COG1263	PTS System
EXD81_RS18935	COG2190	(PTS) system
EXD81_RS18935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_RS18940	COG3711	transcriptional antiterminator
EXD81_RS18945	COG1609	Transcriptional regulator
EXD81_RS18950	COG0006	proline dipeptidase activity
EXD81_RS18955	COG2217	Heavy metal translocating P-type atpase
EXD81_RS18960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_RS18965	COG2244	polysaccharide biosynthetic process
EXD81_RS18970	COG3773	Cell wall hydrolase
EXD81_RS18980	COG4873	Protein conserved in bacteria
EXD81_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_RS19000	COG1733	regulation of RNA biosynthetic process
EXD81_RS19010	COG0602	queuosine metabolic process
EXD81_RS19015	COG0720	synthase
EXD81_RS19030	COG3949	Membrane
EXD81_RS19040	COG0542	response to heat
EXD81_RS19045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXD81_RS19055	COG1846	Transcriptional regulator
EXD81_RS19060	COG3852	Histidine kinase
EXD81_RS19090	COG0436	Aminotransferase
EXD81_RS19095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXD81_RS19110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXD81_RS19115	COG5002	protein histidine kinase activity
EXD81_RS19120	COG3594	Acyltransferase
EXD81_RS19130	COG2323	membrane
EXD81_RS19135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXD81_RS19160	COG1191	sigma factor activity
EXD81_RS19165	COG0861	Integral membrane protein TerC family
EXD81_RS19170	COG0586	Pfam SNARE associated Golgi protein
EXD81_RS19175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EXD81_RS19190	COG1846	Transcriptional regulator
EXD81_RS19205	COG0789	Transcriptional regulator
EXD81_RS19210	COG2239	Acts as a magnesium transporter
EXD81_RS19230	COG1388	LysM domain
EXD81_RS19230	COG3858	chitin binding
EXD81_RS19235	COG4721	ABC-type cobalt transport system, permease component
EXD81_RS19240	COG1122	ATPase activity
EXD81_RS19245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXD81_RS19250	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_RS19255	COG1404	Belongs to the peptidase S8 family
EXD81_RS19265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXD81_RS19270	COG2814	Major facilitator Superfamily
EXD81_RS19280	COG0457	Tetratricopeptide repeat
EXD81_RS19280	COG0463	Glycosyl transferase, family 2
EXD81_RS19295	COG1764	response to oxidative stress
EXD81_RS19300	COG1846	Transcriptional regulator
EXD81_RS19305	COG1764	response to oxidative stress
EXD81_RS19315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXD81_RS19320	COG0788	formyltetrahydrofolate deformylase activity
EXD81_RS19325	COG2076	Multidrug Resistance protein
EXD81_RS19330	COG2076	Multidrug Resistance protein
EXD81_RS19335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_RS19340	COG1607	acyl-coa hydrolase
EXD81_RS19345	COG1834	amidinotransferase
EXD81_RS19350	COG2706	6-phosphogluconolactonase activity
EXD81_RS19355	COG4608	Belongs to the ABC transporter superfamily
EXD81_RS19370	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXD81_RS19375	COG4166	transmembrane transport
EXD81_RS19380	COG0444	Belongs to the ABC transporter superfamily
EXD81_RS19385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_RS19390	COG0601	transmembrane transport
EXD81_RS19395	COG2362	D-Aminopeptidase
EXD81_RS19400	COG0477	Major facilitator Superfamily
EXD81_RS19405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXD81_RS19410	COG0463	Glycosyl transferase, family 2
EXD81_RS19420	COG0346	lactoylglutathione lyase activity
EXD81_RS19425	COG0531	amino acid
EXD81_RS19430	COG1392	Phosphate transport regulator
EXD81_RS19435	COG0306	phosphate transporter
EXD81_RS19450	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_RS19450	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_RS19490	COG3778	Protein conserved in bacteria
EXD81_RS19495	COG3299	homolog of phage Mu protein gp47
EXD81_RS19500	COG3628	GPW Gp25 family protein
EXD81_RS19510	COG4193	domain, Protein
EXD81_RS19515	COG1652	LysM domain
EXD81_RS19570	COG4653	Phage capsid family
EXD81_RS19575	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXD81_RS19580	COG5518	Phage portal protein
EXD81_RS19585	COG1783	phage Terminase large subunit
EXD81_RS19590	COG3728	DNA packaging
EXD81_RS19590	COG5484	DNA packaging
EXD81_RS19595	COG1595	DNA-templated transcription, initiation
EXD81_RS19610	COG1484	DNA-dependent DNA replication
EXD81_RS19615	COG1522	sequence-specific DNA binding
EXD81_RS19625	COG1396	sequence-specific DNA binding
EXD81_RS19630	COG2856	Zn peptidase
EXD81_RS19640	COG4195	phage-related replication protein
EXD81_RS19660	COG0457	Tetratricopeptide repeat
EXD81_RS19665	COG2318	DinB family
EXD81_RS19670	COG0730	response to heat
EXD81_RS19695	COG2197	response regulator
EXD81_RS19700	COG4585	Histidine kinase
EXD81_RS19720	COG2205	protein histidine kinase activity
EXD81_RS19720	COG2770	Histidine kinase
EXD81_RS19725	COG0745	RESPONSE REGULATOR receiver
EXD81_RS19730	COG2721	sulfolactate sulfo-lyase activity
EXD81_RS19735	COG0246	Mannitol dehydrogenase
EXD81_RS19740	COG1609	Transcriptional regulator
EXD81_RS19745	COG2211	Major facilitator Superfamily
EXD81_RS19755	COG1252	NADH dehydrogenase
EXD81_RS19765	COG4297	protein containing double-stranded beta helix domain
EXD81_RS19770	COG0697	spore germination
EXD81_RS19775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXD81_RS19780	COG0390	transport system, permease component
EXD81_RS19785	COG1587	Uroporphyrinogen-III synthase
EXD81_RS19795	COG1819	glycosyl
EXD81_RS19805	COG2427	Protein of unknown function (DUF1641)
EXD81_RS19820	COG2205	protein histidine kinase activity
EXD81_RS19835	COG1285	pathogenesis
EXD81_RS19865	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXD81_RS19880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXD81_RS19895	COG1846	Transcriptional regulator
EXD81_RS19905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXD81_RS19910	COG2367	Beta-lactamase
EXD81_RS19940	COG0626	cystathionine gamma-synthase activity
EXD81_RS19945	COG0626	cystathionine gamma-synthase activity
EXD81_RS19950	COG2382	esterase
EXD81_RS19960	COG2153	protein acetylation
EXD81_RS19990	COG0210	DNA helicase
EXD81_RS20045	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EXD81_RS20050	COG0351	phosphomethylpyrimidine kinase
EXD81_RS20055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_RS20075	COG0352	thiamine-phosphate diphosphorylase activity
EXD81_RS20085	COG0475	glutathione-regulated potassium exporter activity
EXD81_RS20085	COG0569	domain protein
EXD81_RS20100	COG0564	pseudouridine synthase activity
EXD81_RS20110	COG2357	RelA SpoT domain protein
EXD81_RS20125	COG0741	lytic transglycosylase activity
EXD81_RS20130	COG2346	COG2346, Truncated hemoglobins
EXD81_RS20140	COG1164	Oligoendopeptidase f
EXD81_RS20150	COG4862	establishment of competence for transformation
EXD81_RS20155	COG0861	Integral membrane protein TerC family
EXD81_RS20160	COG1393	Belongs to the ArsC family
EXD81_RS20165	COG0456	acetyltransferase
EXD81_RS20175	COG4608	Belongs to the ABC transporter superfamily
EXD81_RS20180	COG0444	Belongs to the ABC transporter superfamily
EXD81_RS20185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_RS20190	COG0601	transmembrane transport
EXD81_RS20200	COG0180	Tryptophanyl-tRNA synthetase
EXD81_RS20210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_RS20215	COG0601	transmembrane transport
EXD81_RS20230	COG0444	Belongs to the ABC transporter superfamily
EXD81_RS20235	COG5504	Zn-dependent protease
EXD81_RS20245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXD81_RS20260	COG1744	ABC transporter substrate-binding protein PnrA-like
EXD81_RS20270	COG2267	carboxylic ester hydrolase activity
EXD81_RS20290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EXD81_RS20295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXD81_RS20300	COG0505	Belongs to the CarA family
EXD81_RS20305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXD81_RS20325	COG2271	Major facilitator Superfamily
EXD81_RS20340	COG2151	metal-sulfur cluster biosynthetic enzyme
EXD81_RS20345	COG1073	alpha beta
EXD81_RS20350	COG0561	phosphatase activity
EXD81_RS20365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_RS20370	COG1307	EDD domain protein, DegV family
EXD81_RS20380	COG2124	cytochrome p450
EXD81_RS20385	COG0840	transmembrane signaling receptor activity
EXD81_RS20395	COG2996	Protein conserved in bacteria