locus-tag	class	description
FOG69_RS00005	COG4463	regulation of RNA biosynthetic process
FOG69_RS00010	COG3880	PFAM UvrB UvrC protein
FOG69_RS00020	COG0542	response to heat
FOG69_RS00025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOG69_RS00030	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FOG69_RS00035	COG4956	integral membrane protein (PIN domain superfamily)
FOG69_RS00055	COG1045	serine acetyltransferase
FOG69_RS00065	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOG69_RS00070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOG69_RS00075	COG3688	RNA-binding protein containing a PIN domain
FOG69_RS00080	COG1595	DNA-templated transcription, initiation
FOG69_RS00090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOG69_RS00095	COG0250	Participates in transcription elongation, termination and antitermination
FOG69_RS00120	COG2813	Specifically methylates the guanine in position
FOG69_RS00135	COG1358	cellular component organization or biogenesis
FOG69_RS00160	COG0596	Alpha beta hydrolase
FOG69_RS00270	COG0201	protein transport
FOG69_RS00280	COG0024	Methionine aminopeptidase
FOG69_RS00295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOG69_RS00320	COG1122	ATPase activity
FOG69_RS00325	COG1122	ATPase activity
FOG69_RS00330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOG69_RS00340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOG69_RS00350	COG2226	methyltransferase
FOG69_RS00360	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS00365	COG0489	protein tyrosine kinase activity
FOG69_RS00375	COG2194	sulfuric ester hydrolase activity
FOG69_RS00380	COG0726	polysaccharide deacetylase
FOG69_RS00440	COG0738	Major facilitator superfamily
FOG69_RS00445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS00460	COG0659	secondary active sulfate transmembrane transporter activity
FOG69_RS00465	COG0385	Bile acid
FOG69_RS00470	COG2819	hydrolase of the alpha beta superfamily
FOG69_RS00475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS00480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS00485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_RS00490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_RS00490	COG2207	Transcriptional regulator
FOG69_RS00495	COG3876	Protein conserved in bacteria
FOG69_RS00500	COG1472	Belongs to the glycosyl hydrolase 3 family
FOG69_RS00505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_RS00510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS00510	COG1263	PTS System
FOG69_RS00520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_RS00525	COG1683	Conserved Protein
FOG69_RS00555	COG1595	DNA-templated transcription, initiation
FOG69_RS00560	COG5662	AntiSigma factor
FOG69_RS00565	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOG69_RS00570	COG4856	YbbR-like protein
FOG69_RS00620	COG1346	cytolysis
FOG69_RS00625	COG1380	Effector of murein hydrolase LrgA
FOG69_RS00630	COG1846	Transcriptional regulator
FOG69_RS00635	COG1113	amino acid transport
FOG69_RS00640	COG1011	Hydrolase
FOG69_RS00645	COG4585	Histidine kinase
FOG69_RS00650	COG2197	response regulator
FOG69_RS00655	COG1131	(ABC) transporter
FOG69_RS00665	COG0842	Transport permease protein
FOG69_RS00665	COG1511	domain protein
FOG69_RS00695	COG0531	amino acid
FOG69_RS00710	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_RS00715	COG2271	Major facilitator Superfamily
FOG69_RS00730	COG2368	4-hydroxyphenylacetate
FOG69_RS00745	COG0371	Dehydrogenase
FOG69_RS00755	COG1183	phosphatidylcholine synthase activity
FOG69_RS00760	COG0586	Pfam SNARE associated Golgi protein
FOG69_RS00765	COG0688	phosphatidylethanolamine metabolic process
FOG69_RS00780	COG1301	dicarboxylic acid transport
FOG69_RS00790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS00795	COG0833	amino acid
FOG69_RS00800	COG2040	homocysteine
FOG69_RS00805	COG1115	amino acid carrier protein
FOG69_RS00810	COG2066	Belongs to the glutaminase family
FOG69_RS00815	COG4191	Histidine kinase
FOG69_RS00820	COG0784	Response regulator, receiver
FOG69_RS00825	COG3173	Aminoglycoside phosphotransferase
FOG69_RS00835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_RS00840	COG0778	Nitroreductase
FOG69_RS00845	COG0346	lactoylglutathione lyase activity
FOG69_RS00850	COG2259	Doxx family
FOG69_RS00855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS00870	COG3773	Cell wall hydrolase
FOG69_RS00875	COG3540	Alkaline phosphatase
FOG69_RS00880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOG69_RS00885	COG0805	protein transport
FOG69_RS00890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FOG69_RS00895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOG69_RS00900	COG0477	Major facilitator Superfamily
FOG69_RS00905	COG1309	transcriptional regulator
FOG69_RS00910	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOG69_RS00915	COG1405	negative regulation of cell septum assembly
FOG69_RS00915	COG3012	SEC-C Motif Domain Protein
FOG69_RS00920	COG0667	Aldo Keto reductase
FOG69_RS00930	COG1595	DNA-templated transcription, initiation
FOG69_RS00935	COG1595	DNA-templated transcription, initiation
FOG69_RS00940	COG1876	peptidase activity
FOG69_RS00945	COG0457	Tetratricopeptide repeat
FOG69_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS00955	COG0366	Alpha amylase catalytic
FOG69_RS00965	COG1695	Transcriptional regulator
FOG69_RS00970	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOG69_RS00975	COG1121	(ABC) transporter
FOG69_RS00980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOG69_RS00985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS00990	COG2310	stress, protein
FOG69_RS00995	COG2310	stress, protein
FOG69_RS01000	COG2310	stress, protein
FOG69_RS01005	COG0861	Integral membrane protein TerC family
FOG69_RS01015	COG3853	Toxic anion resistance protein (TelA)
FOG69_RS01020	COG0477	Major facilitator Superfamily
FOG69_RS01025	COG0517	IMP dehydrogenase activity
FOG69_RS01025	COG4175	Glycine betaine
FOG69_RS01030	COG4176	ABC-type proline glycine betaine transport system permease component
FOG69_RS01035	COG2113	Glycine betaine
FOG69_RS01040	COG1473	amidohydrolase
FOG69_RS01045	COG1288	antiporter activity
FOG69_RS01055	COG1714	RDD family
FOG69_RS01065	COG2814	Major facilitator Superfamily
FOG69_RS01070	COG1846	Transcriptional regulator
FOG69_RS01075	COG1280	lysine exporter protein (LysE YggA)
FOG69_RS01080	COG3403	YqcI/YcgG family
FOG69_RS01085	COG1113	amino acid transport
FOG69_RS01090	COG3665	Urea carboxylase-associated protein
FOG69_RS01100	COG1082	Xylose isomerase domain protein TIM barrel
FOG69_RS01105	COG2271	Major facilitator Superfamily
FOG69_RS01110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOG69_RS01115	COG3458	cephalosporin-C deacetylase activity
FOG69_RS01120	COG3541	Predicted nucleotidyltransferase
FOG69_RS01125	COG0506	proline dehydrogenase activity
FOG69_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS01140	COG2508	Transcriptional regulator
FOG69_RS01150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOG69_RS01150	COG1587	Uroporphyrinogen-III synthase
FOG69_RS01155	COG2146	nitrite reductase [NAD(P)H] activity
FOG69_RS01160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOG69_RS01170	COG0523	cobalamin synthesis protein
FOG69_RS01175	COG1063	alcohol dehydrogenase
FOG69_RS01180	COG1714	RDD family
FOG69_RS01190	COG2723	6-phospho-beta-galactosidase activity
FOG69_RS01200	COG3209	COG3209 Rhs family protein
FOG69_RS01205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOG69_RS01210	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOG69_RS01215	COG1733	regulation of RNA biosynthetic process
FOG69_RS01220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS01225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS01230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS01235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FOG69_RS01250	COG2364	Membrane
FOG69_RS01255	COG1126	abc transporter atp-binding protein
FOG69_RS01260	COG0765	amino acid transport
FOG69_RS01265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS01270	COG0583	DNA-binding transcription factor activity
FOG69_RS01275	COG0163	prenyltransferase activity
FOG69_RS01280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOG69_RS01295	COG3104	oligopeptide transport
FOG69_RS01300	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS01310	COG0697	spore germination
FOG69_RS01320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOG69_RS01325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS01330	COG0456	acetyltransferase
FOG69_RS01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS01340	COG0765	amino acid transport
FOG69_RS01345	COG1126	abc transporter atp-binding protein
FOG69_RS01350	COG1473	amidohydrolase
FOG69_RS01355	COG2079	MmgE PrpD family protein
FOG69_RS01360	COG1136	(ABC) transporter
FOG69_RS01365	COG0577	efflux transmembrane transporter activity
FOG69_RS01370	COG0745	RESPONSE REGULATOR receiver
FOG69_RS01375	COG3850	Histidine kinase
FOG69_RS01375	COG5002	protein histidine kinase activity
FOG69_RS01380	COG0457	Tetratricopeptide repeat
FOG69_RS01395	COG0527	aspartate kinase activity
FOG69_RS01400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS01405	COG4605	iron ion homeostasis
FOG69_RS01410	COG4604	ABC transporter, ATP-binding protein
FOG69_RS01415	COG4607	ABC-type enterochelin transport system periplasmic component
FOG69_RS01420	COG2814	Major facilitator Superfamily
FOG69_RS01425	COG1309	transcriptional regulator
FOG69_RS01430	COG0778	Nitroreductase
FOG69_RS01435	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOG69_RS01440	COG0640	Transcriptional regulator
FOG69_RS01445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS01450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS01455	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS01460	COG4975	Glucose uptake
FOG69_RS01465	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS01470	COG4549	nuclear export factor GLE1
FOG69_RS01475	COG2372	response to copper ion
FOG69_RS01475	COG1276	copper resistance
FOG69_RS01480	COG1349	DNA-binding transcription factor activity
FOG69_RS01490	COG2213	PTS system mannitol-specific
FOG69_RS01495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS01505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOG69_RS01515	COG0561	phosphatase activity
FOG69_RS01525	COG1914	H( )-stimulated, divalent metal cation uptake system
FOG69_RS01535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOG69_RS01540	COG1984	allophanate hydrolase subunit 2
FOG69_RS01545	COG1414	Transcriptional regulator
FOG69_RS01550	COG2755	lipolytic protein G-D-S-L family
FOG69_RS01560	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_RS01565	COG0768	penicillin binding
FOG69_RS01570	COG4989	oxidoreductase activity
FOG69_RS01575	COG3711	transcriptional antiterminator
FOG69_RS01580	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS01590	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS01595	COG1917	Cupin 2, conserved barrel domain protein
FOG69_RS01600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_RS01605	COG3871	stress protein (general stress protein 26)
FOG69_RS01615	COG2814	Major facilitator Superfamily
FOG69_RS01620	COG1522	sequence-specific DNA binding
FOG69_RS01625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOG69_RS01625	COG0551	DNA topoisomerase type I activity
FOG69_RS01630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOG69_RS01635	COG3706	GGDEF domain
FOG69_RS01640	COG5298	Protein conserved in bacteria
FOG69_RS01655	COG0531	amino acid
FOG69_RS01660	COG0028	Belongs to the TPP enzyme family
FOG69_RS01695	COG0457	Tetratricopeptide repeat
FOG69_RS01710	COG1914	H( )-stimulated, divalent metal cation uptake system
FOG69_RS01720	COG4876	unkown
FOG69_RS01730	COG2076	Multidrug Resistance protein
FOG69_RS01735	COG2217	Heavy metal translocating P-type atpase
FOG69_RS01740	COG3729	General stress protein
FOG69_RS01745	COG0662	Cupin 2, conserved barrel domain protein
FOG69_RS01750	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_RS01755	COG3546	catalase activity
FOG69_RS01760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOG69_RS01765	COG3290	protein histidine kinase activity
FOG69_RS01770	COG4565	transcriptional regulatory protein
FOG69_RS01775	COG1301	dicarboxylic acid transport
FOG69_RS01780	COG0628	permease
FOG69_RS01785	COG1131	(ABC) transporter
FOG69_RS01790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_RS01800	COG1960	acyl-CoA dehydrogenase activity
FOG69_RS01820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_RS01825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS01835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOG69_RS01840	COG0513	Belongs to the DEAD box helicase family
FOG69_RS01845	COG3402	PFAM membrane-flanked domain
FOG69_RS01850	COG3428	Bacterial PH domain
FOG69_RS01855	COG0705	Rhomboid family
FOG69_RS01865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOG69_RS01870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOG69_RS01875	COG0864	Transcriptional regulator
FOG69_RS01880	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOG69_RS01885	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS01890	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS01895	COG2172	sigma factor antagonist activity
FOG69_RS01900	COG2208	phosphoserine phosphatase activity
FOG69_RS01905	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS01915	COG1191	sigma factor activity
FOG69_RS01920	COG2208	phosphoserine phosphatase activity
FOG69_RS01925	COG2183	response to ionizing radiation
FOG69_RS01980	COG1764	response to oxidative stress
FOG69_RS01985	COG1846	Transcriptional regulator
FOG69_RS01995	COG0456	acetyltransferase
FOG69_RS01995	COG1846	Transcriptional regulator
FOG69_RS02000	COG2271	Major facilitator Superfamily
FOG69_RS02005	COG4124	Belongs to the glycosyl hydrolase 26 family
FOG69_RS02010	COG2946	Replication initiation factor
FOG69_RS02030	COG1959	2 iron, 2 sulfur cluster binding
FOG69_RS02040	COG1278	Cold shock
FOG69_RS02045	COG1794	racemase activity, acting on amino acids and derivatives
FOG69_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS02065	COG0477	Major facilitator Superfamily
FOG69_RS02070	COG3621	Patatin-like phospholipase
FOG69_RS02080	COG0277	FAD linked oxidase domain protein
FOG69_RS02100	COG0662	Cupin 2, conserved barrel domain protein
FOG69_RS02105	COG0456	acetyltransferase
FOG69_RS02110	COG2207	Transcriptional regulator
FOG69_RS02110	COG3708	Transcriptional regulator
FOG69_RS02135	COG1064	alcohol dehydrogenase
FOG69_RS02140	COG0789	Transcriptional regulator
FOG69_RS02150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS02155	COG2808	Putative FMN-binding domain
FOG69_RS02160	COG2814	Major facilitator Superfamily
FOG69_RS02165	COG1309	transcriptional regulator
FOG69_RS02170	COG0697	spore germination
FOG69_RS02175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS02180	COG5577	PFAM Coat F domain
FOG69_RS02190	COG1063	alcohol dehydrogenase
FOG69_RS02195	COG5577	PFAM Coat F domain
FOG69_RS02205	COG2409	Drug exporters of the RND superfamily
FOG69_RS02210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOG69_RS02215	COG0488	(ABC) transporter
FOG69_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_RS02225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS02235	COG2814	Major facilitator Superfamily
FOG69_RS02240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_RS02250	COG0730	response to heat
FOG69_RS02255	COG0456	acetyltransferase
FOG69_RS02260	COG4978	Transcriptional regulator
FOG69_RS02260	COG0789	Transcriptional regulator
FOG69_RS02265	COG0697	spore germination
FOG69_RS02270	COG1051	belongs to the nudix hydrolase family
FOG69_RS02275	COG0596	Alpha beta hydrolase
FOG69_RS02280	COG0473	3-isopropylmalate dehydrogenase activity
FOG69_RS02285	COG1802	Transcriptional regulator
FOG69_RS02290	COG1819	glycosyl
FOG69_RS02300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_RS02305	COG1388	LysM domain
FOG69_RS02310	COG2814	Major facilitator Superfamily
FOG69_RS02315	COG2188	Transcriptional regulator
FOG69_RS02320	COG2186	Transcriptional regulator
FOG69_RS02325	COG2807	transmembrane transport
FOG69_RS02330	COG2076	Multidrug Resistance protein
FOG69_RS02335	COG2076	Multidrug Resistance protein
FOG69_RS02340	COG1309	transcriptional regulator
FOG69_RS02345	COG0531	amino acid
FOG69_RS02355	COG3832	glyoxalase III activity
FOG69_RS02360	COG0604	alcohol dehydrogenase
FOG69_RS02365	COG2814	Major facilitator Superfamily
FOG69_RS02405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOG69_RS02410	COG0802	atpase or kinase
FOG69_RS02415	COG1214	PFAM Peptidase M22, glycoprotease
FOG69_RS02420	COG0456	acetyltransferase
FOG69_RS02425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOG69_RS02430	COG0488	(ABC) transporter
FOG69_RS02445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOG69_RS02450	COG0805	protein transport
FOG69_RS02460	COG1266	CAAX protease self-immunity
FOG69_RS02475	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS02490	COG0457	Tetratricopeptide repeat
FOG69_RS02495	COG1063	alcohol dehydrogenase
FOG69_RS02505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_RS02515	COG1842	Phage shock protein A
FOG69_RS02520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOG69_RS02525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOG69_RS02530	COG4260	virion core protein, lumpy skin disease virus
FOG69_RS02535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOG69_RS02535	COG2755	lipolytic protein G-D-S-L family
FOG69_RS02545	COG1595	DNA-templated transcription, initiation
FOG69_RS02550	COG1063	alcohol dehydrogenase
FOG69_RS02555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOG69_RS02560	COG0823	Involved in the tonB-independent uptake of proteins
FOG69_RS02570	COG2132	Multicopper oxidase
FOG69_RS02575	COG1113	amino acid transport
FOG69_RS02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_RS02590	COG0714	Associated with various cellular activities
FOG69_RS02595	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOG69_RS02600	COG1305	Transglutaminase-like
FOG69_RS02620	COG2252	PERMEase
FOG69_RS02625	COG3064	Membrane
FOG69_RS02645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOG69_RS02650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOG69_RS02655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOG69_RS02660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOG69_RS02665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOG69_RS02680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOG69_RS02690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOG69_RS02695	COG0138	bifunctional purine biosynthesis protein purh
FOG69_RS02700	COG0151	Belongs to the GarS family
FOG69_RS02705	COG1522	sequence-specific DNA binding
FOG69_RS02710	COG0531	amino acid
FOG69_RS02720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOG69_RS02725	COG1470	cell adhesion involved in biofilm formation
FOG69_RS02730	COG4496	protein, YerC YecD
FOG69_RS02735	COG0069	glutamate synthase activity
FOG69_RS02745	COG0210	DNA helicase
FOG69_RS02755	COG4851	CamS sex pheromone cAM373 precursor
FOG69_RS02760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_RS02765	COG1285	pathogenesis
FOG69_RS02770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_RS02790	COG1309	transcriptional regulator
FOG69_RS02795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOG69_RS02800	COG1597	lipid kinase activity
FOG69_RS02805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOG69_RS02820	COG1131	(ABC) transporter
FOG69_RS02850	COG5444	nuclease activity
FOG69_RS02855	COG5444	nuclease activity
FOG69_RS02885	COG3546	catalase activity
FOG69_RS02890	COG0454	-acetyltransferase
FOG69_RS02900	COG2323	membrane
FOG69_RS02905	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_RS02910	COG0346	lactoylglutathione lyase activity
FOG69_RS02915	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS02920	COG5583	Uncharacterized small protein (DUF2292)
FOG69_RS02925	COG0196	riboflavin kinase activity
FOG69_RS02930	COG0670	Belongs to the BI1 family
FOG69_RS02935	COG1846	Transcriptional regulator
FOG69_RS02940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOG69_RS02950	COG2124	cytochrome p450
FOG69_RS02950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_RS02960	COG1368	sulfuric ester hydrolase activity
FOG69_RS02965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOG69_RS02970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_RS02975	COG1442	glycosyl transferase family 8
FOG69_RS02980	COG1216	Glycosyl transferase, family 2
FOG69_RS02985	COG1442	glycosyl transferase family 8
FOG69_RS02990	COG2223	nitrite transmembrane transporter activity
FOG69_RS02995	COG0531	amino acid
FOG69_RS03000	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS03005	COG0840	transmembrane signaling receptor activity
FOG69_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS03015	COG0457	Tetratricopeptide repeat
FOG69_RS03015	COG0463	Glycosyl transferase, family 2
FOG69_RS03020	COG0488	(ABC) transporter
FOG69_RS03025	COG0789	Transcriptional regulator
FOG69_RS03030	COG2814	Major facilitator Superfamily
FOG69_RS03035	COG0488	(ABC) transporter
FOG69_RS03040	COG0513	Belongs to the DEAD box helicase family
FOG69_RS03045	COG2130	NADP-dependent
FOG69_RS03060	COG3866	Pectate lyase
FOG69_RS03065	COG0471	metal ion transport
FOG69_RS03085	COG2972	Histidine kinase
FOG69_RS03085	COG0745	RESPONSE REGULATOR receiver
FOG69_RS03100	COG3764	Sortase (surface protein transpeptidase)
FOG69_RS03105	COG3290	protein histidine kinase activity
FOG69_RS03110	COG4565	transcriptional regulatory protein
FOG69_RS03115	COG3181	Tripartite tricarboxylate transporter family receptor
FOG69_RS03120	COG2851	Citrate transporter
FOG69_RS03125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS03130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOG69_RS03140	COG2258	MOSC domain
FOG69_RS03155	COG0024	Methionine aminopeptidase
FOG69_RS03160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS03160	COG1263	PTS System
FOG69_RS03170	COG1368	sulfuric ester hydrolase activity
FOG69_RS03180	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_RS03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS03195	COG1263	PTS System
FOG69_RS03200	COG0366	Alpha amylase catalytic
FOG69_RS03205	COG2188	Transcriptional regulator
FOG69_RS03210	COG0778	Nitroreductase
FOG69_RS03225	COG0737	Belongs to the 5'-nucleotidase family
FOG69_RS03230	COG0693	protein deglycase activity
FOG69_RS03235	COG1609	Transcriptional regulator
FOG69_RS03250	COG2814	Major facilitator Superfamily
FOG69_RS03260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOG69_RS03265	COG4980	gas vesicle protein
FOG69_RS03270	COG1295	ribonuclease BN
FOG69_RS03280	COG0477	Major facilitator Superfamily
FOG69_RS03285	COG0387	Pfam Sodium calcium exchanger
FOG69_RS03295	COG0668	transmembrane transport
FOG69_RS03300	COG0535	radical SAM domain protein
FOG69_RS03310	COG0726	polysaccharide deacetylase
FOG69_RS03315	COG2084	Dehydrogenase
FOG69_RS03325	COG0598	Magnesium transport protein CorA
FOG69_RS03330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOG69_RS03335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOG69_RS03350	COG1132	(ABC) transporter
FOG69_RS03355	COG0515	serine threonine protein kinase
FOG69_RS03365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOG69_RS03370	COG4637	Psort location Cytoplasmic, score
FOG69_RS03375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_RS03380	COG0022	dehydrogenase e1 component
FOG69_RS03385	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_RS03390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_RS03395	COG3284	Transcriptional regulator
FOG69_RS03405	COG1486	melibiose metabolic process
FOG69_RS03410	COG1737	Transcriptional regulator
FOG69_RS03415	COG1263	PTS System
FOG69_RS03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS03420	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS03425	COG1132	(ABC) transporter
FOG69_RS03430	COG1132	(ABC) transporter
FOG69_RS03435	COG2259	Doxx family
FOG69_RS03440	COG2514	catechol 2,3-dioxygenase activity
FOG69_RS03450	COG1695	Transcriptional regulator
FOG69_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOG69_RS03460	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FOG69_RS03465	COG2732	(Barnase) inhibitor
FOG69_RS03470	COG2318	DinB family
FOG69_RS03475	COG2814	Major facilitator Superfamily
FOG69_RS03480	COG1846	Transcriptional regulator
FOG69_RS03485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOG69_RS03485	COG0392	lysyltransferase activity
FOG69_RS03490	COG0384	phenazine biosynthesis protein PhzF
FOG69_RS03495	COG0778	Nitroreductase
FOG69_RS03510	COG1090	epimerase
FOG69_RS03525	COG2814	Major facilitator Superfamily
FOG69_RS03535	COG3591	Belongs to the peptidase S1B family
FOG69_RS03550	COG3103	Sh3 type 3 domain protein
FOG69_RS03555	COG5658	integral membrane protein
FOG69_RS03560	COG0596	Alpha beta hydrolase
FOG69_RS03565	COG0463	Glycosyl transferase, family 2
FOG69_RS03570	COG4485	Bacterial membrane protein, YfhO
FOG69_RS03575	COG1988	membrane-bound metal-dependent
FOG69_RS03580	COG1194	a g-specific adenine glycosylase
FOG69_RS03590	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS03610	COG1132	(ABC) transporter
FOG69_RS03615	COG4129	membrane
FOG69_RS03625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOG69_RS03630	COG0735	belongs to the Fur family
FOG69_RS03740	COG1757	Na H antiporter
FOG69_RS03745	COG3340	Belongs to the peptidase S51 family
FOG69_RS03755	COG0277	FAD linked oxidase domain protein
FOG69_RS03765	COG0747	negative chemotaxis
FOG69_RS03770	COG0601	transmembrane transport
FOG69_RS03775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_RS03780	COG0444	Belongs to the ABC transporter superfamily
FOG69_RS03790	COG0753	catalase activity
FOG69_RS03800	COG1116	anion transmembrane transporter activity
FOG69_RS03805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOG69_RS03810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOG69_RS03840	COG1476	TRANSCRIPTIONal
FOG69_RS03850	COG3382	B3 4 domain protein
FOG69_RS03855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOG69_RS03865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOG69_RS03870	COG0789	Transcriptional regulator
FOG69_RS03875	COG1664	Polymer-forming cytoskeletal
FOG69_RS03880	COG1664	Polymer-forming cytoskeletal
FOG69_RS03885	COG2766	serine protein kinase
FOG69_RS03895	COG1846	Transcriptional regulator
FOG69_RS03900	COG1566	PFAM secretion protein HlyD family protein
FOG69_RS03905	COG2814	Major facilitator Superfamily
FOG69_RS03910	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOG69_RS03925	COG1725	Transcriptional regulator
FOG69_RS03930	COG1131	(ABC) transporter
FOG69_RS03935	COG1131	(ABC) transporter
FOG69_RS03940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_RS03945	COG1278	Cold shock
FOG69_RS03950	COG1464	Belongs to the NlpA lipoprotein family
FOG69_RS03955	COG3706	GGDEF domain
FOG69_RS03960	COG1823	symporter activity
FOG69_RS03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_RS03985	COG5577	PFAM Coat F domain
FOG69_RS03990	COG4085	toxin activity
FOG69_RS03990	COG1525	nuclease
FOG69_RS03990	COG0737	Belongs to the 5'-nucleotidase family
FOG69_RS03995	COG3764	Sortase (surface protein transpeptidase)
FOG69_RS04000	COG0564	pseudouridine synthase activity
FOG69_RS04010	COG0517	IMP dehydrogenase activity
FOG69_RS04015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOG69_RS04020	COG3153	acetyltransferase
FOG69_RS04020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOG69_RS04025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_RS04030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOG69_RS04035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOG69_RS04045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOG69_RS04050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOG69_RS04055	COG2203	Gaf domain
FOG69_RS04055	COG4585	Histidine kinase
FOG69_RS04060	COG2197	response regulator
FOG69_RS04065	COG0431	NADPH-dependent FMN reductase
FOG69_RS04080	COG1388	LysM domain
FOG69_RS04080	COG0791	NLP P60 protein
FOG69_RS04085	COG1959	2 iron, 2 sulfur cluster binding
FOG69_RS04090	COG0668	transmembrane transport
FOG69_RS04095	COG2719	SpoVR family
FOG69_RS04100	COG1785	Belongs to the alkaline phosphatase family
FOG69_RS04105	COG1388	LysM domain
FOG69_RS04105	COG0791	NLP P60 protein
FOG69_RS04110	COG0583	DNA-binding transcription factor activity
FOG69_RS04115	COG0372	Belongs to the citrate synthase family
FOG69_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS04125	COG0531	amino acid
FOG69_RS04130	COG0733	neurotransmitter:sodium symporter activity
FOG69_RS04145	COG1595	DNA-templated transcription, initiation
FOG69_RS04150	COG0204	Acyl-transferase
FOG69_RS04155	COG1253	flavin adenine dinucleotide binding
FOG69_RS04160	COG0789	Transcriptional regulator
FOG69_RS04165	COG0436	Aminotransferase
FOG69_RS04170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_RS04175	COG1253	flavin adenine dinucleotide binding
FOG69_RS04180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOG69_RS04185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOG69_RS04190	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_RS04200	COG0668	transmembrane transport
FOG69_RS04205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOG69_RS04210	COG0726	polysaccharide deacetylase
FOG69_RS04215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS04220	COG3226	Transcriptional regulator
FOG69_RS04230	COG0589	response to stress
FOG69_RS04235	COG1132	(ABC) transporter
FOG69_RS04240	COG1132	(ABC) transporter
FOG69_RS04245	COG0702	epimerase
FOG69_RS04260	COG0189	ligase activity
FOG69_RS04265	COG0189	ligase activity
FOG69_RS04280	COG0561	phosphatase activity
FOG69_RS04285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOG69_RS04295	COG0475	glutathione-regulated potassium exporter activity
FOG69_RS04300	COG0490	domain, Protein
FOG69_RS04310	COG1024	Enoyl-CoA hydratase
FOG69_RS04320	COG4152	abc transporter atp-binding protein
FOG69_RS04325	COG1668	transmembrane transport
FOG69_RS04330	COG0420	3'-5' exonuclease activity
FOG69_RS04335	COG4717	serine-type aminopeptidase activity
FOG69_RS04350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOG69_RS04390	COG4980	gas vesicle protein
FOG69_RS04405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOG69_RS04410	COG0537	adenosine 5'-monophosphoramidase activity
FOG69_RS04415	COG1131	(ABC) transporter
FOG69_RS04420	COG4473	ABC transporter
FOG69_RS04430	COG1473	amidohydrolase
FOG69_RS04435	COG3069	C4-dicarboxylate transmembrane transporter activity
FOG69_RS04440	COG2329	Antibiotic biosynthesis monooxygenase
FOG69_RS04445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_RS04455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOG69_RS04460	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FOG69_RS04465	COG1309	transcriptional regulator
FOG69_RS04470	COG1511	domain protein
FOG69_RS04475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_RS04485	COG1363	Peptidase, m42
FOG69_RS04490	COG1301	dicarboxylic acid transport
FOG69_RS04500	COG1234	tRNA 3'-trailer cleavage
FOG69_RS04505	COG0095	Lipoate-protein ligase
FOG69_RS04510	COG0702	epimerase
FOG69_RS04515	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS04525	COG0501	Belongs to the peptidase M48B family
FOG69_RS04530	COG1404	Belongs to the peptidase S8 family
FOG69_RS04540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOG69_RS04545	COG0406	alpha-ribazole phosphatase activity
FOG69_RS04550	COG0183	Belongs to the thiolase family
FOG69_RS04555	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS04560	COG1268	BioY protein
FOG69_RS04565	COG0840	transmembrane signaling receptor activity
FOG69_RS04570	COG0723	plastoquinol--plastocyanin reductase activity
FOG69_RS04570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS04585	COG4903	ComK protein
FOG69_RS04590	COG5646	InterPro IPR014922
FOG69_RS04615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_RS04630	COG0398	Pfam SNARE associated Golgi protein
FOG69_RS04635	COG0681	Belongs to the peptidase S26 family
FOG69_RS04640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOG69_RS04645	COG1846	Transcriptional regulator
FOG69_RS04650	COG3180	Ammonia monooxygenase
FOG69_RS04655	COG2814	Major facilitator Superfamily
FOG69_RS04665	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOG69_RS04670	COG2323	membrane
FOG69_RS04685	COG0420	3'-5' exonuclease activity
FOG69_RS04690	COG0419	ATPase involved in DNA repair
FOG69_RS04695	COG1403	HNH endonuclease
FOG69_RS04735	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOG69_RS04745	COG1404	Belongs to the peptidase S8 family
FOG69_RS04755	COG0367	asparagine synthase
FOG69_RS04760	COG1562	ergosterol biosynthetic process
FOG69_RS04765	COG0534	Mate efflux family protein
FOG69_RS04770	COG2207	Transcriptional regulator
FOG69_RS04770	COG1917	Cupin 2, conserved barrel domain protein
FOG69_RS04775	COG1609	Transcriptional regulator
FOG69_RS04780	COG0673	inositol 2-dehydrogenase activity
FOG69_RS04785	COG2318	DinB family
FOG69_RS04790	COG1279	arginine transmembrane transporter activity
FOG69_RS04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS04800	COG1357	PFAM Pentapeptide repeats (8 copies)
FOG69_RS04805	COG2153	protein acetylation
FOG69_RS04810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOG69_RS04810	COG0646	methionine synthase
FOG69_RS04820	COG2996	Protein conserved in bacteria
FOG69_RS04825	COG1744	ABC transporter substrate-binding protein PnrA-like
FOG69_RS04830	COG0840	transmembrane signaling receptor activity
FOG69_RS04835	COG2124	cytochrome p450
FOG69_RS04845	COG1307	EDD domain protein, DegV family
FOG69_RS04850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS04865	COG0561	phosphatase activity
FOG69_RS04870	COG1073	alpha beta
FOG69_RS04875	COG2151	metal-sulfur cluster biosynthetic enzyme
FOG69_RS04885	COG0277	FAD linked oxidase domain protein
FOG69_RS04890	COG2271	Major facilitator Superfamily
FOG69_RS04900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOG69_RS04910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOG69_RS04915	COG0505	Belongs to the CarA family
FOG69_RS04920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOG69_RS04925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOG69_RS04945	COG2267	carboxylic ester hydrolase activity
FOG69_RS04955	COG1744	ABC transporter substrate-binding protein PnrA-like
FOG69_RS04970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_RS04975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOG69_RS04980	COG5504	Zn-dependent protease
FOG69_RS04985	COG0444	Belongs to the ABC transporter superfamily
FOG69_RS04990	COG4608	Belongs to the ABC transporter superfamily
FOG69_RS05000	COG0601	transmembrane transport
FOG69_RS05005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_RS05015	COG0180	Tryptophanyl-tRNA synthetase
FOG69_RS05025	COG4166	transmembrane transport
FOG69_RS05030	COG0601	transmembrane transport
FOG69_RS05035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_RS05040	COG0444	Belongs to the ABC transporter superfamily
FOG69_RS05045	COG4608	Belongs to the ABC transporter superfamily
FOG69_RS05055	COG0456	acetyltransferase
FOG69_RS05060	COG1393	Belongs to the ArsC family
FOG69_RS05065	COG0861	Integral membrane protein TerC family
FOG69_RS05070	COG4862	establishment of competence for transformation
FOG69_RS05075	COG4469	Competence protein
FOG69_RS05080	COG1164	Oligoendopeptidase f
FOG69_RS05085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOG69_RS05090	COG2346	COG2346, Truncated hemoglobins
FOG69_RS05095	COG0741	lytic transglycosylase activity
FOG69_RS05100	COG4116	CYTH
FOG69_RS05110	COG2357	RelA SpoT domain protein
FOG69_RS05115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOG69_RS05120	COG0564	pseudouridine synthase activity
FOG69_RS05130	COG0475	glutathione-regulated potassium exporter activity
FOG69_RS05130	COG0569	domain protein
FOG69_RS05135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOG69_RS05140	COG0352	thiamine-phosphate diphosphorylase activity
FOG69_RS05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_RS05150	COG2104	thiamine diphosphate biosynthetic process
FOG69_RS05160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOG69_RS05165	COG0351	phosphomethylpyrimidine kinase
FOG69_RS05170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOG69_RS05225	COG0210	DNA helicase
FOG69_RS05235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS05245	COG1131	(ABC) transporter
FOG69_RS05255	COG2153	protein acetylation
FOG69_RS05265	COG2382	esterase
FOG69_RS05270	COG0626	cystathionine gamma-synthase activity
FOG69_RS05275	COG0626	cystathionine gamma-synthase activity
FOG69_RS05285	COG0582	viral genome integration into host DNA
FOG69_RS05290	COG2856	Zn peptidase
FOG69_RS05300	COG1525	nuclease
FOG69_RS05305	COG3620	sequence-specific DNA binding
FOG69_RS05355	COG3935	DnaD domain protein
FOG69_RS05360	COG1484	DNA-dependent DNA replication
FOG69_RS05365	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOG69_RS05440	COG3677	Transposase
FOG69_RS05455	COG5484	DNA packaging
FOG69_RS05530	COG3953	SLT domain
FOG69_RS05530	COG5280	Phage tail tape measure protein TP901
FOG69_RS05620	COG5444	nuclease activity
FOG69_RS05650	COG0582	viral genome integration into host DNA
FOG69_RS05660	COG4282	regulation of fungal-type cell wall biogenesis
FOG69_RS05705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_RS05755	COG2367	Beta-lactamase
FOG69_RS05760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOG69_RS05765	COG0477	Major facilitator Superfamily
FOG69_RS05770	COG1846	Transcriptional regulator
FOG69_RS05785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS05785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS05790	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_RS05795	COG2723	6-phospho-beta-galactosidase activity
FOG69_RS05800	COG1349	DNA-binding transcription factor activity
FOG69_RS05820	COG1285	pathogenesis
FOG69_RS05830	COG2205	protein histidine kinase activity
FOG69_RS05840	COG3383	formate dehydrogenase (NAD+) activity
FOG69_RS05845	COG2427	Protein of unknown function (DUF1641)
FOG69_RS05850	COG2124	cytochrome p450
FOG69_RS05855	COG1819	glycosyl
FOG69_RS05865	COG1587	Uroporphyrinogen-III synthase
FOG69_RS05870	COG0390	transport system, permease component
FOG69_RS05875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_RS05880	COG0697	spore germination
FOG69_RS05885	COG4297	protein containing double-stranded beta helix domain
FOG69_RS05895	COG1252	NADH dehydrogenase
FOG69_RS05905	COG1609	Transcriptional regulator
FOG69_RS05915	COG0745	RESPONSE REGULATOR receiver
FOG69_RS05920	COG2770	Histidine kinase
FOG69_RS05920	COG2205	protein histidine kinase activity
FOG69_RS05935	COG0730	response to heat
FOG69_RS05940	COG2318	DinB family
FOG69_RS05945	COG0457	Tetratricopeptide repeat
FOG69_RS05955	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS05955	COG1388	LysM domain
FOG69_RS05955	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS05965	COG4195	phage-related replication protein
FOG69_RS05970	COG2856	Zn peptidase
FOG69_RS05975	COG1396	sequence-specific DNA binding
FOG69_RS05985	COG1522	sequence-specific DNA binding
FOG69_RS05990	COG1484	DNA-dependent DNA replication
FOG69_RS06005	COG1595	DNA-templated transcription, initiation
FOG69_RS06010	COG5484	DNA packaging
FOG69_RS06010	COG3728	DNA packaging
FOG69_RS06015	COG1783	phage Terminase large subunit
FOG69_RS06020	COG5518	Phage portal protein
FOG69_RS06025	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOG69_RS06030	COG4653	Phage capsid family
FOG69_RS06080	COG3953	SLT domain
FOG69_RS06080	COG3953	SLT domain
FOG69_RS06080	COG5412	phage tail tape measure protein
FOG69_RS06080	COG5412	phage tail tape measure protein
FOG69_RS06080	COG5412	phage tail tape measure protein
FOG69_RS06080	COG3953	SLT domain
FOG69_RS06085	COG1652	LysM domain
FOG69_RS06090	COG4193	domain, Protein
FOG69_RS06100	COG3628	GPW Gp25 family protein
FOG69_RS06105	COG3299	homolog of phage Mu protein gp47
FOG69_RS06110	COG3778	Protein conserved in bacteria
FOG69_RS06150	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS06150	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS06165	COG0306	phosphate transporter
FOG69_RS06170	COG1392	Phosphate transport regulator
FOG69_RS06175	COG0531	amino acid
FOG69_RS06180	COG0346	lactoylglutathione lyase activity
FOG69_RS06185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOG69_RS06190	COG0463	Glycosyl transferase, family 2
FOG69_RS06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_RS06200	COG0477	Major facilitator Superfamily
FOG69_RS06205	COG2362	D-Aminopeptidase
FOG69_RS06210	COG0601	transmembrane transport
FOG69_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOG69_RS06220	COG0444	Belongs to the ABC transporter superfamily
FOG69_RS06225	COG4166	transmembrane transport
FOG69_RS06230	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOG69_RS06235	COG4948	Mandelate Racemase Muconate Lactonizing
FOG69_RS06240	COG0791	NLP P60 protein
FOG69_RS06245	COG4608	Belongs to the ABC transporter superfamily
FOG69_RS06250	COG2706	6-phosphogluconolactonase activity
FOG69_RS06255	COG1834	amidinotransferase
FOG69_RS06260	COG1607	acyl-coa hydrolase
FOG69_RS06265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOG69_RS06270	COG2076	Multidrug Resistance protein
FOG69_RS06275	COG2076	Multidrug Resistance protein
FOG69_RS06280	COG0788	formyltetrahydrofolate deformylase activity
FOG69_RS06285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOG69_RS06295	COG1764	response to oxidative stress
FOG69_RS06300	COG1846	Transcriptional regulator
FOG69_RS06305	COG1764	response to oxidative stress
FOG69_RS06320	COG0457	Tetratricopeptide repeat
FOG69_RS06320	COG0463	Glycosyl transferase, family 2
FOG69_RS06335	COG2814	Major facilitator Superfamily
FOG69_RS06340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_RS06350	COG1404	Belongs to the peptidase S8 family
FOG69_RS06355	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS06360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOG69_RS06365	COG1122	ATPase activity
FOG69_RS06370	COG4721	ABC-type cobalt transport system, permease component
FOG69_RS06375	COG1388	LysM domain
FOG69_RS06375	COG3858	chitin binding
FOG69_RS06390	COG2239	Acts as a magnesium transporter
FOG69_RS06395	COG0789	Transcriptional regulator
FOG69_RS06410	COG1846	Transcriptional regulator
FOG69_RS06415	COG0726	polysaccharide deacetylase
FOG69_RS06420	COG3285	dna ligase
FOG69_RS06420	COG1793	dna ligase
FOG69_RS06425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOG69_RS06430	COG5001	Diguanylate cyclase
FOG69_RS06430	COG3300	MHYT domain
FOG69_RS06435	COG0586	Pfam SNARE associated Golgi protein
FOG69_RS06440	COG0861	Integral membrane protein TerC family
FOG69_RS06445	COG1191	sigma factor activity
FOG69_RS06470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOG69_RS06475	COG2323	membrane
FOG69_RS06485	COG3594	Acyltransferase
FOG69_RS06490	COG5002	protein histidine kinase activity
FOG69_RS06495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOG69_RS06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOG69_RS06515	COG0436	Aminotransferase
FOG69_RS06550	COG3852	Histidine kinase
FOG69_RS06555	COG1846	Transcriptional regulator
FOG69_RS06560	COG1360	Flagellar Motor Protein
FOG69_RS06565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOG69_RS06570	COG0542	response to heat
FOG69_RS06580	COG3949	Membrane
FOG69_RS06595	COG0720	synthase
FOG69_RS06600	COG0602	queuosine metabolic process
FOG69_RS06615	COG4873	Protein conserved in bacteria
FOG69_RS06625	COG3773	Cell wall hydrolase
FOG69_RS06630	COG2244	polysaccharide biosynthetic process
FOG69_RS06635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS06640	COG2217	Heavy metal translocating P-type atpase
FOG69_RS06645	COG0006	proline dipeptidase activity
FOG69_RS06650	COG1609	Transcriptional regulator
FOG69_RS06655	COG3711	transcriptional antiterminator
FOG69_RS06660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS06660	COG2190	(PTS) system
FOG69_RS06660	COG1263	PTS System
FOG69_RS06665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS06670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOG69_RS06680	COG1533	DNA photolyase activity
FOG69_RS06685	COG0840	transmembrane signaling receptor activity
FOG69_RS06690	COG2084	Dehydrogenase
FOG69_RS06700	COG2340	Cysteine-rich secretory protein family
FOG69_RS06705	COG0768	penicillin binding
FOG69_RS06710	COG4191	Histidine kinase
FOG69_RS06715	COG0436	Aminotransferase
FOG69_RS06725	COG0784	Response regulator, receiver
FOG69_RS06725	COG0835	chemotaxis
FOG69_RS06735	COG2814	Major facilitator Superfamily
FOG69_RS06740	COG1376	ErfK ybiS ycfS ynhG family protein
FOG69_RS06745	COG1408	metallophosphoesterase
FOG69_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS06760	COG2200	EAL domain
FOG69_RS06765	COG4703	Protein of unknown function (DUF1797)
FOG69_RS06770	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOG69_RS06780	COG0517	IMP dehydrogenase activity
FOG69_RS06785	COG0583	DNA-binding transcription factor activity
FOG69_RS06790	COG0716	FMN binding
FOG69_RS06800	COG0716	FMN binding
FOG69_RS06820	COG0668	transmembrane transport
FOG69_RS06830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS06850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOG69_RS06855	COG0303	'Molybdopterin
FOG69_RS06860	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOG69_RS06865	COG0314	molybdopterin synthase activity
FOG69_RS06870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOG69_RS06880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOG69_RS06885	COG1136	(ABC) transporter
FOG69_RS06890	COG0577	efflux transmembrane transporter activity
FOG69_RS06895	COG1349	DNA-binding transcription factor activity
FOG69_RS06900	COG1105	Belongs to the carbohydrate kinase PfkB family
FOG69_RS06905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_RS06905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_RS06905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS06910	COG0681	Belongs to the peptidase S26 family
FOG69_RS06920	COG0488	(ABC) transporter
FOG69_RS06925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOG69_RS06930	COG2309	aminopeptidase activity
FOG69_RS06940	COG1077	Cell shape determining protein MreB Mrl
FOG69_RS06950	COG2002	toxin-antitoxin pair type II binding
FOG69_RS06955	COG3852	Histidine kinase
FOG69_RS06960	COG2105	PFAM AIG2 family protein
FOG69_RS06960	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FOG69_RS06965	COG0569	domain protein
FOG69_RS06975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOG69_RS06990	COG0561	phosphatase activity
FOG69_RS06995	COG0242	peptide deformylase activity
FOG69_RS07005	COG0497	DNA recombination
FOG69_RS07010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_RS07015	COG0022	dehydrogenase e1 component
FOG69_RS07020	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_RS07025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_RS07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS07045	COG1982	Orn Lys Arg decarboxylase major
FOG69_RS07070	COG0483	inositol monophosphate 1-phosphatase activity
FOG69_RS07080	COG3227	Zinc metalloprotease (Elastase)
FOG69_RS07105	COG1217	gtp-binding protein TYPA
FOG69_RS07115	COG4896	Protein conserved in bacteria
FOG69_RS07125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOG69_RS07130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOG69_RS07135	COG2066	Belongs to the glutaminase family
FOG69_RS07145	COG0772	Belongs to the SEDS family
FOG69_RS07150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOG69_RS07165	COG2010	Cytochrome c
FOG69_RS07165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOG69_RS07170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOG69_RS07175	COG1845	cytochrome c oxidase, subunit III
FOG69_RS07180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOG69_RS07185	COG3336	cytochrome c oxidase
FOG69_RS07195	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOG69_RS07200	COG2340	Cysteine-rich secretory protein family
FOG69_RS07215	COG3679	Belongs to the UPF0342 family
FOG69_RS07225	COG0742	ribosomal rna small subunit methyltransferase
FOG69_RS07235	COG3314	Sporulation integral membrane protein YlbJ
FOG69_RS07240	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOG69_RS07245	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOG69_RS07255	COG1399	metal-binding, possibly nucleic acid-binding protein
FOG69_RS07275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOG69_RS07295	COG4839	cell division protein FtsL
FOG69_RS07300	COG0768	penicillin binding
FOG69_RS07305	COG0768	penicillin binding
FOG69_RS07325	COG0772	Belongs to the SEDS family
FOG69_RS07340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOG69_RS07345	COG0849	cell division
FOG69_RS07350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOG69_RS07355	COG4412	M6 family metalloprotease domain protein
FOG69_RS07355	COG1404	Belongs to the peptidase S8 family
FOG69_RS07365	COG1191	sigma factor activity
FOG69_RS07370	COG1191	sigma factor activity
FOG69_RS07375	COG1119	ATPase activity
FOG69_RS07380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_RS07385	COG1873	PFAM PRC-barrel domain
FOG69_RS07390	COG1496	oxidoreductase activity
FOG69_RS07395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOG69_RS07405	COG0762	integral membrane protein
FOG69_RS07410	COG2302	S4 RNA-binding domain
FOG69_RS07415	COG3599	regulation of cell shape
FOG69_RS07425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOG69_RS07430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_RS07440	COG0564	pseudouridine synthase activity
FOG69_RS07450	COG2233	PERMEase
FOG69_RS07460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOG69_RS07465	COG0505	Belongs to the CarA family
FOG69_RS07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOG69_RS07485	COG0284	orotidine-5'-phosphate decarboxylase activity
FOG69_RS07490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOG69_RS07500	COG0306	phosphate transporter
FOG69_RS07515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOG69_RS07525	COG1648	precorrin-2 dehydrogenase activity
FOG69_RS07540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOG69_RS07545	COG1561	YicC-like family, N-terminal region
FOG69_RS07555	COG0194	GDP metabolic process
FOG69_RS07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOG69_RS07570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOG69_RS07575	COG0242	peptide deformylase activity
FOG69_RS07585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOG69_RS07585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOG69_RS07595	COG0631	protein serine/threonine phosphatase activity
FOG69_RS07600	COG2815	serine threonine protein kinase
FOG69_RS07600	COG0515	serine threonine protein kinase
FOG69_RS07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOG69_RS07615	COG1564	THIamine pyrophosphokinase
FOG69_RS07630	COG1302	Protein conserved in bacteria
FOG69_RS07635	COG1461	Dihydroxyacetone kinase
FOG69_RS07640	COG1760	l-serine dehydratase
FOG69_RS07645	COG1760	l-serine dehydratase
FOG69_RS07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOG69_RS07665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOG69_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS07685	COG1196	nuclear chromosome segregation
FOG69_RS07690	COG0552	protein localization to endoplasmic reticulum
FOG69_RS07700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOG69_RS07710	COG1837	Belongs to the UPF0109 family
FOG69_RS07735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOG69_RS07750	COG2257	FlhB HrpN YscU SpaS Family
FOG69_RS07760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOG69_RS07765	COG0758	DNA mediated transformation
FOG69_RS07770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOG69_RS07780	COG4974	Belongs to the 'phage' integrase family
FOG69_RS07805	COG1558	bacterial-type flagellum-dependent cell motility
FOG69_RS07810	COG1677	Flagellar hook-basal body complex protein FliE
FOG69_RS07815	COG1766	The M ring may be actively involved in energy transduction
FOG69_RS07820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_RS07825	COG1317	bacterial-type flagellum organization
FOG69_RS07830	COG1157	protein secretion by the type III secretion system
FOG69_RS07835	COG2882	bacterial-type flagellum organization
FOG69_RS07840	COG3334	PFAM MgtE intracellular
FOG69_RS07845	COG3144	bacterial-type flagellum assembly
FOG69_RS07850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOG69_RS07855	COG4786	Flagellar basal body rod
FOG69_RS07860	COG1582	Flagellar protein (FlbD)
FOG69_RS07865	COG1580	Controls the rotational direction of flagella during chemotaxis
FOG69_RS07870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_RS07875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOG69_RS07875	COG1776	CheC inhibitor of MCP methylation
FOG69_RS07880	COG2201	protein-glutamate methylesterase activity
FOG69_RS07885	COG3190	flagellar
FOG69_RS07890	COG1338	Plays a role in the flagellum-specific transport system
FOG69_RS07895	COG1987	bacterial-type flagellum assembly
FOG69_RS07900	COG1684	flagellar biosynthetic protein fliR
FOG69_RS07905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOG69_RS07910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOG69_RS07915	COG1419	protein localization to endoplasmic reticulum
FOG69_RS07920	COG0455	bacterial-type flagellum organization
FOG69_RS07925	COG2201	protein-glutamate methylesterase activity
FOG69_RS07930	COG0643	Histidine kinase
FOG69_RS07930	COG2198	Histidine kinase
FOG69_RS07935	COG0835	chemotaxis
FOG69_RS07940	COG1776	CheC inhibitor of MCP methylation
FOG69_RS07950	COG1191	sigma factor activity
FOG69_RS07980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOG69_RS07985	COG4589	Belongs to the CDS family
FOG69_RS07995	COG0750	zinc metalloprotease
FOG69_RS08005	COG2176	DNA-directed DNA polymerase activity
FOG69_RS08015	COG0195	Participates in both transcription termination and antitermination
FOG69_RS08020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOG69_RS08025	COG1358	cellular component organization or biogenesis
FOG69_RS08035	COG1550	Protein conserved in bacteria
FOG69_RS08050	COG0196	riboflavin kinase activity
FOG69_RS08065	COG0726	polysaccharide deacetylase
FOG69_RS08070	COG0612	Peptidase, M16
FOG69_RS08075	COG1873	PFAM PRC-barrel domain
FOG69_RS08080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOG69_RS08085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOG69_RS08090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOG69_RS08095	COG0527	aspartate kinase activity
FOG69_RS08105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOG69_RS08110	COG0740	serine-type endopeptidase activity
FOG69_RS08120	COG1674	ftsk spoiiie
FOG69_RS08120	COG4980	gas vesicle protein
FOG69_RS08125	COG2188	Transcriptional regulator
FOG69_RS08130	COG2814	Major facilitator Superfamily
FOG69_RS08135	COG1846	Transcriptional regulator
FOG69_RS08140	COG1033	growth of symbiont in host cell
FOG69_RS08140	COG2409	Drug exporters of the RND superfamily
FOG69_RS08145	COG0612	Peptidase, M16
FOG69_RS08150	COG0612	Peptidase, M16
FOG69_RS08155	COG0300	oxidoreductase activity
FOG69_RS08170	COG1426	Protein conserved in bacteria
FOG69_RS08175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOG69_RS08190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOG69_RS08200	COG1692	metallophosphoesterase
FOG69_RS08205	COG2359	stage V sporulation protein S
FOG69_RS08225	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOG69_RS08265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_RS08270	COG3425	synthase
FOG69_RS08275	COG1024	Enoyl-CoA hydratase
FOG69_RS08280	COG1024	Enoyl-CoA hydratase
FOG69_RS08285	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS08285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08285	COG0300	oxidoreductase activity
FOG69_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS08285	COG3321	synthase
FOG69_RS08290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_RS08290	COG3321	synthase
FOG69_RS08290	COG4221	oxidoreductase activity
FOG69_RS08290	COG0300	oxidoreductase activity
FOG69_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS08295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_RS08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_RS08295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_RS08295	COG3321	synthase
FOG69_RS08295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08295	COG3321	synthase
FOG69_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS08300	COG3321	synthase
FOG69_RS08300	COG4221	oxidoreductase activity
FOG69_RS08300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOG69_RS08305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOG69_RS08305	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FOG69_RS08305	COG3321	synthase
FOG69_RS08310	COG2124	cytochrome p450
FOG69_RS08315	COG3209	COG3209 Rhs family protein
FOG69_RS08320	COG3619	membrane
FOG69_RS08330	COG1404	Belongs to the peptidase S8 family
FOG69_RS08340	COG4195	phage-related replication protein
FOG69_RS08345	COG1764	response to oxidative stress
FOG69_RS08355	COG2076	Multidrug Resistance protein
FOG69_RS08395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_RS08400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_RS08405	COG4112	unkown
FOG69_RS08415	COG0464	growth
FOG69_RS08420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOG69_RS08425	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOG69_RS08430	COG0789	Transcriptional regulator
FOG69_RS08435	COG0174	glutamine synthetase
FOG69_RS08470	COG0726	polysaccharide deacetylase
FOG69_RS08475	COG2124	cytochrome p450
FOG69_RS08480	COG2211	Major facilitator Superfamily
FOG69_RS08485	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_RS08500	COG1070	Carbohydrate kinase
FOG69_RS08510	COG0574	Belongs to the PEP-utilizing enzyme family
FOG69_RS08510	COG3848	Pyruvate phosphate dikinase
FOG69_RS08520	COG1063	alcohol dehydrogenase
FOG69_RS08530	COG0457	Tetratricopeptide repeat
FOG69_RS08545	COG2318	DinB family
FOG69_RS08550	COG1064	alcohol dehydrogenase
FOG69_RS08570	COG0456	acetyltransferase
FOG69_RS08605	COG3397	chitin binding
FOG69_RS08620	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS08625	COG2314	TM2 domain
FOG69_RS08630	COG0756	dUTP diphosphatase activity
FOG69_RS08640	COG4195	phage-related replication protein
FOG69_RS08670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOG69_RS08680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOG69_RS08700	COG0785	Cytochrome C biogenesis protein
FOG69_RS08705	COG2201	protein-glutamate methylesterase activity
FOG69_RS08710	COG4846	Membrane protein involved in cytochrome C biogenesis
FOG69_RS08720	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_RS08735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOG69_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS08760	COG0824	Thioesterase
FOG69_RS08770	COG4841	protein insertion into membrane
FOG69_RS08780	COG1832	CoA-binding protein
FOG69_RS08785	COG0187	DNA topoisomerase II activity
FOG69_RS08790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOG69_RS08800	COG1115	amino acid carrier protein
FOG69_RS08830	COG2205	protein histidine kinase activity
FOG69_RS08835	COG0745	RESPONSE REGULATOR receiver
FOG69_RS08845	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS08880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOG69_RS08885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOG69_RS08890	COG2124	cytochrome p450
FOG69_RS08910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_RS08920	COG2246	polysaccharide biosynthetic process
FOG69_RS08925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOG69_RS08930	COG0586	Pfam SNARE associated Golgi protein
FOG69_RS08935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOG69_RS08940	COG1024	Enoyl-CoA hydratase
FOG69_RS08945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOG69_RS08950	COG0511	ligase activity, forming carbon-carbon bonds
FOG69_RS08955	COG0439	Biotin carboxylase
FOG69_RS08960	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS08965	COG1960	acyl-CoA dehydrogenase activity
FOG69_RS08970	COG1649	PFAM Uncharacterised BCR, COG1649
FOG69_RS08980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FOG69_RS08985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS08995	COG2027	D-alanyl-D-alanine carboxypeptidase
FOG69_RS09000	COG2017	converts alpha-aldose to the beta-anomer
FOG69_RS09005	COG0534	Mate efflux family protein
FOG69_RS09020	COG0582	viral genome integration into host DNA
FOG69_RS09025	COG0166	Belongs to the GPI family
FOG69_RS09030	COG0405	Gamma-glutamyltransferase
FOG69_RS09035	COG2814	Major facilitator Superfamily
FOG69_RS09040	COG0640	Transcriptional regulator
FOG69_RS09045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOG69_RS09055	COG0604	alcohol dehydrogenase
FOG69_RS09065	COG0493	'glutamate synthase
FOG69_RS09070	COG0067	glutamate synthase
FOG69_RS09070	COG0070	glutamate synthase
FOG69_RS09070	COG0069	glutamate synthase activity
FOG69_RS09075	COG0583	DNA-binding transcription factor activity
FOG69_RS09080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOG69_RS09095	COG0300	oxidoreductase activity
FOG69_RS09100	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FOG69_RS09110	COG2814	Major facilitator Superfamily
FOG69_RS09115	COG1070	Carbohydrate kinase
FOG69_RS09120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOG69_RS09125	COG0243	molybdopterin cofactor binding
FOG69_RS09155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_RS09160	COG2207	Transcriptional regulator
FOG69_RS09160	COG0662	Cupin 2, conserved barrel domain protein
FOG69_RS09165	COG1309	transcriptional regulator
FOG69_RS09170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS09180	COG0640	Transcriptional regulator
FOG69_RS09185	COG0741	lytic transglycosylase activity
FOG69_RS09190	COG2322	membrane
FOG69_RS09205	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOG69_RS09215	COG1388	LysM domain
FOG69_RS09215	COG3584	3D domain protein
FOG69_RS09220	COG0514	ATP-dependent DNA helicase (RecQ)
FOG69_RS09230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOG69_RS09235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_RS09250	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_RS09280	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS09285	COG1657	PFAM Prenyltransferase squalene oxidase
FOG69_RS09290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOG69_RS09295	COG0733	neurotransmitter:sodium symporter activity
FOG69_RS09300	COG0385	Bile acid
FOG69_RS09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS09310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_RS09320	COG4548	von Willebrand factor, type A
FOG69_RS09325	COG0714	Associated with various cellular activities
FOG69_RS09330	COG2032	superoxide dismutase activity
FOG69_RS09335	COG1388	LysM domain
FOG69_RS09335	COG0791	NLP P60 protein
FOG69_RS09340	COG1819	glycosyl
FOG69_RS09345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOG69_RS09350	COG0534	Mate efflux family protein
FOG69_RS09355	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS09360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_RS09365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_RS09375	COG2962	Rard protein
FOG69_RS09390	COG1942	4-Oxalocrotonate Tautomerase
FOG69_RS09400	COG1733	regulation of RNA biosynthetic process
FOG69_RS09405	COG0778	Nitroreductase
FOG69_RS09410	COG0400	carboxylic ester hydrolase activity
FOG69_RS09415	COG0346	lactoylglutathione lyase activity
FOG69_RS09425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOG69_RS09435	COG2723	6-phospho-beta-galactosidase activity
FOG69_RS09440	COG2188	Transcriptional regulator
FOG69_RS09445	COG0793	Belongs to the peptidase S41A family
FOG69_RS09445	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS09450	COG2226	methyltransferase
FOG69_RS09460	COG1876	peptidase activity
FOG69_RS09480	COG0671	phosphoesterase, PA-phosphatase related
FOG69_RS09495	COG0346	lactoylglutathione lyase activity
FOG69_RS09510	COG1509	lysine 2,3-aminomutase activity
FOG69_RS09515	COG0456	acetyltransferase
FOG69_RS09520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_RS09525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOG69_RS09530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOG69_RS09535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOG69_RS09545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOG69_RS09555	COG0456	acetyltransferase
FOG69_RS09560	COG0463	Glycosyl transferase, family 2
FOG69_RS09575	COG4641	Protein conserved in bacteria
FOG69_RS09585	COG1086	Polysaccharide biosynthesis protein
FOG69_RS09610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOG69_RS09615	COG1086	Polysaccharide biosynthesis protein
FOG69_RS09630	COG1846	Transcriptional regulator
FOG69_RS09635	COG4698	Protein conserved in bacteria
FOG69_RS09640	COG2755	lipolytic protein G-D-S-L family
FOG69_RS09645	COG1999	signal sequence binding
FOG69_RS09655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOG69_RS09660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOG69_RS09665	COG1272	protein, Hemolysin III
FOG69_RS09670	COG0204	Acyl-transferase
FOG69_RS09675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_RS09680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOG69_RS09690	COG2136	Putative SAM-dependent methyltransferase
FOG69_RS09690	COG2521	methyltransferase
FOG69_RS09705	COG1413	lyase activity
FOG69_RS09710	COG1418	mRNA catabolic process
FOG69_RS09715	COG0386	Belongs to the glutathione peroxidase family
FOG69_RS09725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOG69_RS09735	COG1278	Cold shock
FOG69_RS09755	COG0328	RNA-DNA hybrid ribonuclease activity
FOG69_RS09760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOG69_RS09765	COG0328	RNA-DNA hybrid ribonuclease activity
FOG69_RS09775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_RS09790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOG69_RS09800	COG1755	Isoprenylcysteine carboxyl methyltransferase
FOG69_RS09805	COG3424	synthase
FOG69_RS09835	COG3331	DNA recombination
FOG69_RS09865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_RS09870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOG69_RS09890	COG0756	dUTP diphosphatase activity
FOG69_RS09935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOG69_RS09940	COG1780	Probably involved in ribonucleotide reductase function
FOG69_RS10020	COG0270	DNA (cytosine-5-)-methyltransferase activity
FOG69_RS10030	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FOG69_RS10035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOG69_RS10045	COG3584	3D domain protein
FOG69_RS10055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOG69_RS10095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOG69_RS10100	COG3420	alginic acid biosynthetic process
FOG69_RS10100	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS10105	COG4195	phage-related replication protein
FOG69_RS10140	COG2135	peptidase activity
FOG69_RS10145	COG1793	dna ligase
FOG69_RS10265	COG0582	viral genome integration into host DNA
FOG69_RS10370	COG3655	Transcriptional regulator
FOG69_RS10400	COG3645	SOS response
FOG69_RS10400	COG3646	Phage regulatory protein
FOG69_RS10405	COG0210	DNA helicase
FOG69_RS10470	COG0776	regulation of translation
FOG69_RS10600	COG0582	viral genome integration into host DNA
FOG69_RS10615	COG2815	serine threonine protein kinase
FOG69_RS10615	COG0515	serine threonine protein kinase
FOG69_RS10645	COG2433	Pfam Transposase IS66
FOG69_RS10655	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS10660	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS10660	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS10685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_RS10715	COG5444	nuclease activity
FOG69_RS10725	COG4282	regulation of fungal-type cell wall biogenesis
FOG69_RS10730	COG1525	nuclease
FOG69_RS10750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOG69_RS10755	COG1199	ATP-dependent helicase activity
FOG69_RS10775	COG0116	Belongs to the methyltransferase superfamily
FOG69_RS10805	COG3359	exonuclease
FOG69_RS10810	COG1111	helicase
FOG69_RS10810	COG1205	dead DEAH box helicase
FOG69_RS10815	COG2190	(PTS) system
FOG69_RS10820	COG0071	Belongs to the small heat shock protein (HSP20) family
FOG69_RS10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_RS10860	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOG69_RS10870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOG69_RS10875	COG3935	DnaD domain protein
FOG69_RS10885	COG0436	Aminotransferase
FOG69_RS10890	COG5353	protein conserved in bacteria
FOG69_RS10900	COG1199	ATP-dependent helicase activity
FOG69_RS10900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOG69_RS10930	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS10935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_RS10950	COG1694	Mazg nucleotide pyrophosphohydrolase
FOG69_RS10955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS10960	COG2140	Oxalate decarboxylase
FOG69_RS10970	COG4347	Protein of unknown function (DUF1405)
FOG69_RS10975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOG69_RS10975	COG2010	Cytochrome c
FOG69_RS10980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOG69_RS10985	COG0723	plastoquinol--plastocyanin reductase activity
FOG69_RS11000	COG0457	Tetratricopeptide repeat
FOG69_RS11010	COG0287	Prephenate dehydrogenase
FOG69_RS11045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOG69_RS11050	COG4401	Chorismate mutase type I
FOG69_RS11065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOG69_RS11070	COG0105	UTP biosynthetic process
FOG69_RS11075	COG0142	geranyltranstransferase activity
FOG69_RS11085	COG0142	geranyltranstransferase activity
FOG69_RS11100	COG0776	regulation of translation
FOG69_RS11105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOG69_RS11145	COG0539	negative regulation of cytoplasmic translation
FOG69_RS11155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOG69_RS11160	COG2959	enzyme of heme biosynthesis
FOG69_RS11165	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS11165	COG3773	Cell wall hydrolase
FOG69_RS11170	COG2339	peptidase activity
FOG69_RS11175	COG0492	ferredoxin-NADP+ reductase activity
FOG69_RS11180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_RS11185	COG4862	establishment of competence for transformation
FOG69_RS11190	COG1408	metallophosphoesterase
FOG69_RS11200	COG1388	LysM domain
FOG69_RS11205	COG1266	CAAX protease self-immunity
FOG69_RS11210	COG0514	ATP-dependent DNA helicase (RecQ)
FOG69_RS11215	COG4955	Helix-turn-helix domain
FOG69_RS11220	COG1141	Ferredoxin
FOG69_RS11225	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOG69_RS11230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOG69_RS11240	COG1595	DNA-templated transcription, initiation
FOG69_RS11245	COG5002	protein histidine kinase activity
FOG69_RS11250	COG0745	RESPONSE REGULATOR receiver
FOG69_RS11255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOG69_RS11260	COG1333	cytochrome c biogenesis protein
FOG69_RS11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS11270	COG1187	pseudouridine synthase activity
FOG69_RS11275	COG0700	Nucleoside recognition
FOG69_RS11280	COG2715	membrane protein required for spore maturation
FOG69_RS11285	COG1686	Belongs to the peptidase S11 family
FOG69_RS11310	COG1547	Domain of unknown function (DUF309)
FOG69_RS11320	COG0456	acetyltransferase
FOG69_RS11325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOG69_RS11330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOG69_RS11330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOG69_RS11335	COG0307	riboflavin synthase, alpha
FOG69_RS11340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOG69_RS11340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOG69_RS11350	COG0681	Belongs to the peptidase S26 family
FOG69_RS11360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOG69_RS11365	COG4086	secreted protein
FOG69_RS11370	COG0019	diaminopimelate decarboxylase activity
FOG69_RS11375	COG0697	spore germination
FOG69_RS11390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOG69_RS11410	COG1191	sigma factor activity
FOG69_RS11420	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS11425	COG1686	Belongs to the peptidase S11 family
FOG69_RS11430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOG69_RS11435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOG69_RS11440	COG4974	Belongs to the 'phage' integrase family
FOG69_RS11450	COG0735	belongs to the Fur family
FOG69_RS11455	COG1300	Membrane
FOG69_RS11470	COG0281	malic enzyme
FOG69_RS11475	COG1757	Na H antiporter
FOG69_RS11480	COG1027	Aspartate ammonia-lyase
FOG69_RS11485	COG0252	asparaginase activity
FOG69_RS11490	COG1396	sequence-specific DNA binding
FOG69_RS11495	COG1379	DNA repair
FOG69_RS11500	COG0494	nUDIX hydrolase
FOG69_RS11510	COG0667	Aldo Keto reductase
FOG69_RS11520	COG1073	alpha beta
FOG69_RS11530	COG4918	Iron-sulphur cluster biosynthesis
FOG69_RS11535	COG0456	acetyltransferase
FOG69_RS11535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOG69_RS11540	COG0456	acetyltransferase
FOG69_RS11545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOG69_RS11560	COG0628	permease
FOG69_RS11575	COG3048	D-serine ammonia-lyase activity
FOG69_RS11580	COG0300	oxidoreductase activity
FOG69_RS11585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS11590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOG69_RS11615	COG0596	Alpha beta hydrolase
FOG69_RS11630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOG69_RS11635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOG69_RS11650	COG0706	membrane insertase activity
FOG69_RS11655	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOG69_RS11660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOG69_RS11665	COG0346	lactoylglutathione lyase activity
FOG69_RS11670	COG1376	ErfK ybiS ycfS ynhG family protein
FOG69_RS11675	COG4129	membrane
FOG69_RS11680	COG1126	abc transporter atp-binding protein
FOG69_RS11685	COG0765	amino acid transport
FOG69_RS11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS11700	COG1597	lipid kinase activity
FOG69_RS11705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOG69_RS11710	COG0022	dehydrogenase e1 component
FOG69_RS11715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOG69_RS11720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOG69_RS11725	COG3426	butyrate kinase activity
FOG69_RS11730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_RS11735	COG0280	phosphate acetyltransferase
FOG69_RS11740	COG3829	transcription factor binding
FOG69_RS11740	COG3290	protein histidine kinase activity
FOG69_RS11750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOG69_RS11755	COG2079	MmgE PrpD family protein
FOG69_RS11760	COG0372	Belongs to the citrate synthase family
FOG69_RS11765	COG1960	acyl-CoA dehydrogenase activity
FOG69_RS11770	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOG69_RS11775	COG0183	Belongs to the thiolase family
FOG69_RS11780	COG0584	glycerophosphoryl diester phosphodiesterase
FOG69_RS11785	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS11805	COG1902	pentaerythritol trinitrate reductase activity
FOG69_RS11820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOG69_RS11825	COG0745	RESPONSE REGULATOR receiver
FOG69_RS11830	COG0750	zinc metalloprotease
FOG69_RS11835	COG0497	DNA recombination
FOG69_RS11845	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOG69_RS11855	COG0142	geranyltranstransferase activity
FOG69_RS11865	COG1570	exodeoxyribonuclease VII activity
FOG69_RS11880	COG1302	Protein conserved in bacteria
FOG69_RS11885	COG0439	Biotin carboxylase
FOG69_RS11890	COG0511	ligase activity, forming carbon-carbon bonds
FOG69_RS11930	COG3854	ATPases associated with a variety of cellular activities
FOG69_RS11945	COG0006	proline dipeptidase activity
FOG69_RS11955	COG3872	metal-dependent enzyme
FOG69_RS11965	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOG69_RS11980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOG69_RS12000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOG69_RS12015	COG1396	sequence-specific DNA binding
FOG69_RS12025	COG0681	Belongs to the peptidase S26 family
FOG69_RS12050	COG4940	Competence protein ComGF
FOG69_RS12060	COG4970	Tfp pilus assembly protein FimT
FOG69_RS12065	COG4537	Required for transformation and DNA binding
FOG69_RS12070	COG1459	type II secretion system
FOG69_RS12075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOG69_RS12080	COG0598	Magnesium transport protein CorA
FOG69_RS12085	COG1253	flavin adenine dinucleotide binding
FOG69_RS12090	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS12100	COG1393	Belongs to the ArsC family
FOG69_RS12110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS12120	COG0011	TIGRFAM Protein of
FOG69_RS12130	COG2866	Carboxypeptidase
FOG69_RS12135	COG1940	carbohydrate kinase activity
FOG69_RS12140	COG4483	Protein conserved in bacteria
FOG69_RS12145	COG1757	Na H antiporter
FOG69_RS12155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOG69_RS12170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOG69_RS12175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_RS12180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOG69_RS12185	COG0581	inorganic phosphate transmembrane transporter activity
FOG69_RS12190	COG0573	inorganic phosphate transmembrane transporter activity
FOG69_RS12195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOG69_RS12200	COG0768	penicillin binding
FOG69_RS12205	COG0477	Major facilitator Superfamily
FOG69_RS12210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOG69_RS12215	COG2839	Protein conserved in bacteria
FOG69_RS12220	COG5521	maltodextrose utilization protein MalA
FOG69_RS12225	COG1388	LysM domain
FOG69_RS12235	COG4709	membrane
FOG69_RS12240	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FOG69_RS12245	COG0735	belongs to the Fur family
FOG69_RS12250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS12265	COG0513	Belongs to the DEAD box helicase family
FOG69_RS12280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOG69_RS12285	COG2384	SAM-dependent methyltransferase
FOG69_RS12290	COG2010	Cytochrome c
FOG69_RS12295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOG69_RS12300	COG0358	DNA primase activity
FOG69_RS12315	COG0517	IMP dehydrogenase activity
FOG69_RS12320	COG0751	glycine-tRNA ligase activity
FOG69_RS12340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOG69_RS12345	COG0295	cytidine deaminase activity
FOG69_RS12350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOG69_RS12360	COG1480	7TM receptor with intracellular HD hydrolase
FOG69_RS12365	COG1702	phosphate starvation-inducible protein PhoH
FOG69_RS12370	COG0561	phosphatase activity
FOG69_RS12385	COG4864	UPF0365 protein
FOG69_RS12390	COG1030	water channel activity
FOG69_RS12395	COG1610	YqeY-like protein
FOG69_RS12405	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOG69_RS12410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOG69_RS12415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOG69_RS12445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOG69_RS12460	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS12475	COG1466	dna polymerase III delta subunit
FOG69_RS12490	COG2333	competence protein COMEC
FOG69_RS12490	COG0658	competence protein
FOG69_RS12495	COG2131	deaminase
FOG69_RS12500	COG1555	photosystem II stabilization
FOG69_RS12500	COG1596	polysaccharide export
FOG69_RS12505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOG69_RS12510	COG2226	methyltransferase
FOG69_RS12515	COG0799	negative regulation of ribosome biogenesis
FOG69_RS12520	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOG69_RS12530	COG1534	Rna-binding protein
FOG69_RS12535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOG69_RS12540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOG69_RS12545	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOG69_RS12555	COG2755	lipolytic protein G-D-S-L family
FOG69_RS12565	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS12565	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS12570	COG0398	Pfam SNARE associated Golgi protein
FOG69_RS12610	COG0563	adenylate kinase activity
FOG69_RS12620	COG2814	Major facilitator Superfamily
FOG69_RS12630	COG0456	acetyltransferase
FOG69_RS12635	COG2318	DinB family
FOG69_RS12640	COG0561	phosphatase activity
FOG69_RS12645	COG0561	phosphatase activity
FOG69_RS12655	COG1482	cell wall glycoprotein biosynthetic process
FOG69_RS12660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_RS12660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS12660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOG69_RS12665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS12665	COG3711	transcriptional antiterminator
FOG69_RS12675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOG69_RS12680	COG0583	DNA-binding transcription factor activity
FOG69_RS12685	COG2814	Major facilitator Superfamily
FOG69_RS12690	COG2124	cytochrome p450
FOG69_RS12690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_RS12695	COG1309	transcriptional regulator
FOG69_RS12700	COG2226	methyltransferase
FOG69_RS12710	COG2116	formate transmembrane transporter activity
FOG69_RS12715	COG5609	conserved protein (DUF2294)
FOG69_RS12720	COG3383	formate dehydrogenase (NAD+) activity
FOG69_RS12725	COG2427	Protein of unknown function (DUF1641)
FOG69_RS12735	COG0626	cystathionine gamma-synthase activity
FOG69_RS12740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_RS12765	COG0768	penicillin binding
FOG69_RS12780	COG0826	peptidase U32
FOG69_RS12785	COG0826	peptidase U32
FOG69_RS12790	COG4122	O-methyltransferase activity
FOG69_RS12795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOG69_RS12810	COG4472	Bacterial protein of unknown function (DUF965)
FOG69_RS12820	COG0628	permease
FOG69_RS12825	COG1126	abc transporter atp-binding protein
FOG69_RS12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS12835	COG0765	amino acid transport
FOG69_RS12840	COG0765	amino acid transport
FOG69_RS12855	COG3881	PFAM PRC-barrel domain
FOG69_RS12860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOG69_RS12865	COG0457	Tetratricopeptide repeat
FOG69_RS12875	COG1104	cysteine desulfurase activity
FOG69_RS12880	COG1959	2 iron, 2 sulfur cluster binding
FOG69_RS12885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOG69_RS12890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOG69_RS12915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS12915	COG3103	Sh3 type 3 domain protein
FOG69_RS12915	COG4991	sh3 domain protein
FOG69_RS12920	COG1490	D-aminoacyl-tRNA deacylase activity
FOG69_RS12925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOG69_RS12935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOG69_RS12935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOG69_RS12940	COG5416	Lipopolysaccharide assembly protein A domain
FOG69_RS12945	COG0490	domain, Protein
FOG69_RS12950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOG69_RS12950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOG69_RS12960	COG2244	polysaccharide biosynthetic process
FOG69_RS12965	COG2323	membrane
FOG69_RS12975	COG1862	Preprotein translocase
FOG69_RS13015	COG1388	LysM domain
FOG69_RS13025	COG0157	Belongs to the NadC ModD family
FOG69_RS13030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOG69_RS13035	COG1104	cysteine desulfurase activity
FOG69_RS13040	COG1827	regulation of RNA biosynthetic process
FOG69_RS13045	COG0077	Prephenate dehydratase
FOG69_RS13060	COG3290	protein histidine kinase activity
FOG69_RS13065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOG69_RS13070	COG2868	ribosomal protein
FOG69_RS13080	COG1994	Peptidase M50
FOG69_RS13085	COG0739	heme binding
FOG69_RS13090	COG2894	cell division
FOG69_RS13095	COG0850	regulation of cytokinetic process
FOG69_RS13100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOG69_RS13110	COG1077	Cell shape determining protein MreB Mrl
FOG69_RS13130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOG69_RS13135	COG0285	dihydrofolate synthase activity
FOG69_RS13140	COG0525	valine-tRNA ligase activity
FOG69_RS13150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_RS13155	COG1388	LysM domain
FOG69_RS13165	COG0113	porphobilinogen synthase activity
FOG69_RS13170	COG1587	Uroporphyrinogen-III synthase
FOG69_RS13180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOG69_RS13200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOG69_RS13205	COG1067	ATP-dependent peptidase activity
FOG69_RS13205	COG0470	DNA polymerase III
FOG69_RS13220	COG1477	protein flavinylation
FOG69_RS13220	COG0457	Tetratricopeptide repeat
FOG69_RS13235	COG0473	3-isopropylmalate dehydrogenase activity
FOG69_RS13250	COG0440	acetolactate synthase activity
FOG69_RS13255	COG0028	Belongs to the TPP enzyme family
FOG69_RS13280	COG0622	Phosphoesterase
FOG69_RS13285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOG69_RS13295	COG5401	PFAM Sporulation and spore germination
FOG69_RS13305	COG1846	Transcriptional regulator
FOG69_RS13310	COG2197	response regulator
FOG69_RS13315	COG0824	Thioesterase
FOG69_RS13320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOG69_RS13325	COG1053	succinate dehydrogenase
FOG69_RS13330	COG2009	succinate dehydrogenase
FOG69_RS13335	COG1719	4-vinyl reductase, 4VR
FOG69_RS13340	COG0527	aspartate kinase activity
FOG69_RS13350	COG3118	belongs to the thioredoxin family
FOG69_RS13355	COG3534	alpha-L-arabinofuranosidase
FOG69_RS13360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOG69_RS13365	COG2086	electron transfer activity
FOG69_RS13370	COG1024	Enoyl-CoA hydratase
FOG69_RS13375	COG1309	transcriptional regulator
FOG69_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
FOG69_RS13390	COG3766	membrane
FOG69_RS13400	COG1796	DNA polymerase
FOG69_RS13400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOG69_RS13405	COG1286	toxin biosynthetic process
FOG69_RS13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_RS13420	COG0072	phenylalanine-tRNA ligase activity
FOG69_RS13425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOG69_RS13430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOG69_RS13440	COG3835	regulator
FOG69_RS13445	COG0277	FAD linked oxidase domain protein
FOG69_RS13450	COG0247	lactate metabolic process
FOG69_RS13455	COG1966	Carbon starvation protein
FOG69_RS13460	COG3534	alpha-L-arabinofuranosidase
FOG69_RS13465	COG0395	ABC-type sugar transport system, permease component
FOG69_RS13470	COG1175	transmembrane transport
FOG69_RS13475	COG1653	transport
FOG69_RS13485	COG0647	UMP catabolic process
FOG69_RS13490	COG0235	Class ii aldolase
FOG69_RS13495	COG1069	ribulokinase activity
FOG69_RS13500	COG2160	L-arabinose isomerase activity
FOG69_RS13505	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_RS13510	COG1363	Peptidase, m42
FOG69_RS13520	COG3326	Membrane
FOG69_RS13525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOG69_RS13535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOG69_RS13540	COG1346	cytolysis
FOG69_RS13545	COG1380	Effector of murein hydrolase LrgA
FOG69_RS13550	COG3279	Response regulator of the LytR AlgR family
FOG69_RS13555	COG3275	phosphorelay sensor kinase activity
FOG69_RS13560	COG1011	Hydrolase
FOG69_RS13575	COG0398	Pfam SNARE associated Golgi protein
FOG69_RS13580	COG1484	DNA-dependent DNA replication
FOG69_RS13585	COG3611	Membrane attachment protein
FOG69_RS13600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOG69_RS13605	COG1733	regulation of RNA biosynthetic process
FOG69_RS13610	COG2814	Major facilitator Superfamily
FOG69_RS13615	COG0656	L-ascorbic acid biosynthetic process
FOG69_RS13620	COG0237	dephospho-CoA kinase activity
FOG69_RS13625	COG1971	Probably functions as a manganese efflux pump
FOG69_RS13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOG69_RS13635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_RS13635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOG69_RS13640	COG5002	protein histidine kinase activity
FOG69_RS13645	COG0745	RESPONSE REGULATOR receiver
FOG69_RS13655	COG0538	isocitrate dehydrogenase activity
FOG69_RS13660	COG0372	Belongs to the citrate synthase family
FOG69_RS13670	COG0628	permease
FOG69_RS13675	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOG69_RS13680	COG0469	pyruvate kinase activity
FOG69_RS13700	COG0281	malic enzyme
FOG69_RS13705	COG0587	DNA-directed DNA polymerase activity
FOG69_RS13725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOG69_RS13735	COG4109	DRTGG domain
FOG69_RS13745	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS13760	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOG69_RS13770	COG0827	DNA restriction-modification system
FOG69_RS13775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOG69_RS13780	COG3874	Sporulation protein YtfJ
FOG69_RS13790	COG1714	RDD family
FOG69_RS13795	COG0616	signal peptide processing
FOG69_RS13800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOG69_RS13805	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOG69_RS13810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOG69_RS13825	COG1104	cysteine desulfurase activity
FOG69_RS13830	COG1114	Component of the transport system for branched-chain amino acids
FOG69_RS13840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOG69_RS13845	COG1309	transcriptional regulator
FOG69_RS13850	COG1956	GAF domain-containing protein
FOG69_RS13855	COG2203	Gaf domain
FOG69_RS13855	COG2199	diguanylate cyclase activity
FOG69_RS13870	COG1017	nitric oxide dioxygenase activity
FOG69_RS13870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOG69_RS13895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOG69_RS13900	COG1378	Sugar-specific transcriptional regulator TrmB
FOG69_RS13905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOG69_RS13920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOG69_RS13925	COG0454	-acetyltransferase
FOG69_RS13930	COG0517	IMP dehydrogenase activity
FOG69_RS13935	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOG69_RS13940	COG1360	Flagellar Motor Protein
FOG69_RS13945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOG69_RS13950	COG1609	Transcriptional regulator
FOG69_RS13955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOG69_RS13955	COG1605	Chorismate mutase
FOG69_RS13960	COG3118	belongs to the thioredoxin family
FOG69_RS13965	COG4980	gas vesicle protein
FOG69_RS13970	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FOG69_RS13980	COG1674	ftsk spoiiie
FOG69_RS13985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_RS13995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS14005	COG1363	Peptidase, m42
FOG69_RS14010	COG5584	Small secreted protein
FOG69_RS14015	COG0281	malic enzyme
FOG69_RS14020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOG69_RS14035	COG0510	thiamine kinase activity
FOG69_RS14040	COG1597	lipid kinase activity
FOG69_RS14050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOG69_RS14055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_RS14060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_RS14065	COG2252	PERMEase
FOG69_RS14070	COG4473	ABC transporter
FOG69_RS14075	COG1131	(ABC) transporter
FOG69_RS14080	COG1349	DNA-binding transcription factor activity
FOG69_RS14085	COG1187	pseudouridine synthase activity
FOG69_RS14090	COG2244	polysaccharide biosynthetic process
FOG69_RS14095	COG2081	HI0933 family
FOG69_RS14100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOG69_RS14110	COG1609	Transcriptional regulator
FOG69_RS14115	COG1653	transport
FOG69_RS14120	COG1175	transmembrane transport
FOG69_RS14125	COG0395	ABC-type sugar transport system, permease component
FOG69_RS14130	COG1486	melibiose metabolic process
FOG69_RS14140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOG69_RS14155	COG1366	Belongs to the anti-sigma-factor antagonist family
FOG69_RS14155	COG2202	Pas domain
FOG69_RS14160	COG2814	Major facilitator Superfamily
FOG69_RS14165	COG5522	Integral membrane protein (intg_mem_TP0381)
FOG69_RS14170	COG0577	efflux transmembrane transporter activity
FOG69_RS14175	COG1136	(ABC) transporter
FOG69_RS14180	COG2205	protein histidine kinase activity
FOG69_RS14185	COG0745	RESPONSE REGULATOR receiver
FOG69_RS14190	COG0577	efflux transmembrane transporter activity
FOG69_RS14195	COG1136	(ABC) transporter
FOG69_RS14215	COG1131	(ABC) transporter
FOG69_RS14220	COG1725	Transcriptional regulator
FOG69_RS14230	COG1242	4 iron, 4 sulfur cluster binding
FOG69_RS14235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOG69_RS14250	COG2267	carboxylic ester hydrolase activity
FOG69_RS14255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOG69_RS14260	COG1113	amino acid transport
FOG69_RS14265	COG0367	asparagine synthase
FOG69_RS14285	COG1506	peptidase
FOG69_RS14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOG69_RS14295	COG1116	anion transmembrane transporter activity
FOG69_RS14300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOG69_RS14305	COG0494	nUDIX hydrolase
FOG69_RS14310	COG4824	toxin secretion phage lysis holin
FOG69_RS14315	COG0783	Belongs to the Dps family
FOG69_RS14340	COG0288	reversible hydration of carbon dioxide
FOG69_RS14350	COG1271	oxidase subunit
FOG69_RS14355	COG1294	oxidase, subunit
FOG69_RS14365	COG4948	Mandelate Racemase Muconate Lactonizing
FOG69_RS14375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOG69_RS14380	COG0596	Alpha beta hydrolase
FOG69_RS14390	COG1169	isochorismate synthase
FOG69_RS14395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOG69_RS14400	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FOG69_RS14525	COG3859	Proton-coupled thiamine transporter YuaJ
FOG69_RS14530	COG2268	Band 7 protein
FOG69_RS14535	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOG69_RS14540	COG2318	DinB family
FOG69_RS14550	COG1454	alcohol dehydrogenase
FOG69_RS14555	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS14560	COG1510	regulation of RNA biosynthetic process
FOG69_RS14570	COG0569	domain protein
FOG69_RS14575	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOG69_RS14580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOG69_RS14580	COG1017	nitric oxide dioxygenase activity
FOG69_RS14595	COG0457	Tetratricopeptide repeat
FOG69_RS14655	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS14660	COG4824	toxin secretion phage lysis holin
FOG69_RS14680	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS14695	COG3953	SLT domain
FOG69_RS14695	COG5412	phage tail tape measure protein
FOG69_RS14840	COG0582	viral genome integration into host DNA
FOG69_RS14855	COG0628	permease
FOG69_RS14860	COG0673	inositol 2-dehydrogenase activity
FOG69_RS14865	COG0693	protein deglycase activity
FOG69_RS14870	COG0840	transmembrane signaling receptor activity
FOG69_RS14875	COG0840	transmembrane signaling receptor activity
FOG69_RS14880	COG0840	transmembrane signaling receptor activity
FOG69_RS14885	COG0840	transmembrane signaling receptor activity
FOG69_RS14900	COG2070	2-Nitropropane dioxygenase
FOG69_RS14910	COG0366	Alpha amylase catalytic
FOG69_RS14915	COG1253	flavin adenine dinucleotide binding
FOG69_RS14920	COG2738	Putative neutral zinc metallopeptidase
FOG69_RS14935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOG69_RS14955	COG1979	alcohol dehydrogenase
FOG69_RS14960	COG1979	alcohol dehydrogenase
FOG69_RS14965	COG2155	Conserved Protein
FOG69_RS14970	COG1098	S1 RNA binding domain
FOG69_RS14975	COG0436	Aminotransferase
FOG69_RS14980	COG1522	sequence-specific DNA binding
FOG69_RS14985	COG2267	carboxylic ester hydrolase activity
FOG69_RS14995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOG69_RS15000	COG2205	protein histidine kinase activity
FOG69_RS15010	COG5018	Exonuclease
FOG69_RS15015	COG2814	Major facilitator Superfamily
FOG69_RS15020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_RS15025	COG3011	Protein conserved in bacteria
FOG69_RS15035	COG3290	protein histidine kinase activity
FOG69_RS15040	COG4565	transcriptional regulatory protein
FOG69_RS15045	COG1744	ABC transporter substrate-binding protein PnrA-like
FOG69_RS15050	COG3845	ABC transporter
FOG69_RS15055	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOG69_RS15060	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOG69_RS15070	COG2111	Na H antiporter
FOG69_RS15070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOG69_RS15075	COG2111	Na H antiporter
FOG69_RS15080	COG1006	Multisubunit Na H antiporter MnhC subunit
FOG69_RS15085	COG0651	ATP synthesis coupled electron transport
FOG69_RS15090	COG1863	multisubunit Na H antiporter MnhE subunit
FOG69_RS15095	COG2212	antiporter activity
FOG69_RS15100	COG1320	monovalent cation:proton antiporter activity
FOG69_RS15105	COG2050	protein possibly involved in aromatic compounds catabolism
FOG69_RS15110	COG2197	response regulator
FOG69_RS15115	COG4585	Histidine kinase
FOG69_RS15125	COG0142	geranyltranstransferase activity
FOG69_RS15145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOG69_RS15150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOG69_RS15155	COG1335	isochorismatase
FOG69_RS15160	COG5506	Protein of unknown function (DUF1694)
FOG69_RS15175	COG0628	permease
FOG69_RS15185	COG1418	mRNA catabolic process
FOG69_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS15200	COG1511	domain protein
FOG69_RS15205	COG0433	COG0433 Predicted ATPase
FOG69_RS15205	COG1674	ftsk spoiiie
FOG69_RS15210	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOG69_RS15215	COG5417	Belongs to the EsaB family
FOG69_RS15220	COG4842	Belongs to the WXG100 family
FOG69_RS15225	COG2508	Transcriptional regulator
FOG69_RS15225	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOG69_RS15230	COG0686	Belongs to the AlaDH PNT family
FOG69_RS15235	COG5634	Uncharacterized conserved protein (DUF2278)
FOG69_RS15240	COG3251	PFAM MbtH domain protein
FOG69_RS15245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOG69_RS15250	COG1535	isochorismatase
FOG69_RS15250	COG3433	isochorismatase activity
FOG69_RS15255	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOG69_RS15260	COG1169	isochorismate synthase
FOG69_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS15270	COG2819	hydrolase of the alpha beta superfamily
FOG69_RS15275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOG69_RS15280	COG1268	BioY protein
FOG69_RS15285	COG2056	Na+-H+ antiporter family
FOG69_RS15295	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOG69_RS15300	COG3584	3D domain protein
FOG69_RS15315	COG1252	NADH dehydrogenase
FOG69_RS15345	COG1131	(ABC) transporter
FOG69_RS15370	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FOG69_RS15390	COG1388	LysM domain
FOG69_RS15390	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS15390	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS15415	COG5434	Belongs to the glycosyl hydrolase 28 family
FOG69_RS15425	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOG69_RS15510	COG0582	viral genome integration into host DNA
FOG69_RS15605	COG4974	Belongs to the 'phage' integrase family
FOG69_RS15610	COG0316	Belongs to the HesB IscA family
FOG69_RS15620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_RS15630	COG1252	NADH dehydrogenase
FOG69_RS15635	COG4837	Protein of unknown function (DUF1462)
FOG69_RS15640	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOG69_RS15645	COG4946	Tricorn protease homolog
FOG69_RS15645	COG0823	Involved in the tonB-independent uptake of proteins
FOG69_RS15645	COG1506	peptidase
FOG69_RS15655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOG69_RS15660	COG0460	homoserine dehydrogenase
FOG69_RS15665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOG69_RS15670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOG69_RS15675	COG0647	UMP catabolic process
FOG69_RS15680	COG2445	Protein of unknown function DUF86
FOG69_RS15685	COG4470	Protein conserved in bacteria
FOG69_RS15700	COG0739	heme binding
FOG69_RS15710	COG0737	Belongs to the 5'-nucleotidase family
FOG69_RS15715	COG0730	response to heat
FOG69_RS15720	COG1801	Protein of unknown function DUF72
FOG69_RS15735	COG2508	Transcriptional regulator
FOG69_RS15745	COG3195	allantoin biosynthetic process
FOG69_RS15745	COG3648	Uricase
FOG69_RS15755	COG2814	Major facilitator Superfamily
FOG69_RS15760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOG69_RS15765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOG69_RS15770	COG2356	endonuclease I
FOG69_RS15775	COG3842	ATPase activity
FOG69_RS15780	COG2188	Transcriptional regulator
FOG69_RS15785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_RS15790	COG0395	ABC-type sugar transport system, permease component
FOG69_RS15795	COG1175	transmembrane transport
FOG69_RS15800	COG1653	transport
FOG69_RS15805	COG2222	sugar isomerase
FOG69_RS15810	COG0789	Transcriptional regulator
FOG69_RS15835	COG0322	excinuclease ABC activity
FOG69_RS15840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOG69_RS15855	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS15860	COG0719	Fe-S assembly protein
FOG69_RS15865	COG0822	iron-sulfur transferase activity
FOG69_RS15870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOG69_RS15875	COG0719	Fe-S assembly protein
FOG69_RS15880	COG0396	ATPase activity
FOG69_RS15895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOG69_RS15900	COG1464	Belongs to the NlpA lipoprotein family
FOG69_RS15905	COG2011	ABC-type metal ion transport system permease component
FOG69_RS15910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOG69_RS15920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOG69_RS15925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOG69_RS15940	COG1393	Belongs to the ArsC family
FOG69_RS15945	COG1960	acyl-CoA dehydrogenase activity
FOG69_RS15950	COG0183	Belongs to the thiolase family
FOG69_RS15955	COG1024	Enoyl-CoA hydratase
FOG69_RS15955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOG69_RS15975	COG5577	PFAM Coat F domain
FOG69_RS15980	COG1846	Transcriptional regulator
FOG69_RS15985	COG0477	Major facilitator Superfamily
FOG69_RS16015	COG1120	ATPase activity
FOG69_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS16035	COG0783	Belongs to the Dps family
FOG69_RS16040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_RS16045	COG0745	RESPONSE REGULATOR receiver
FOG69_RS16050	COG2205	protein histidine kinase activity
FOG69_RS16050	COG2770	Histidine kinase
FOG69_RS16060	COG1309	transcriptional regulator
FOG69_RS16065	COG0114	fumarate hydratase activity
FOG69_RS16075	COG0697	spore germination
FOG69_RS16080	COG0814	amino acid
FOG69_RS16090	COG2197	response regulator
FOG69_RS16095	COG4585	Histidine kinase
FOG69_RS16100	COG4758	membrane
FOG69_RS16105	COG3595	metallopeptidase activity
FOG69_RS16110	COG1842	Phage shock protein A
FOG69_RS16115	COG4758	membrane
FOG69_RS16120	COG2814	Major facilitator Superfamily
FOG69_RS16125	COG2096	Adenosyltransferase
FOG69_RS16130	COG1120	ATPase activity
FOG69_RS16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS16140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS16150	COG3386	PFAM SMP-30 Gluconolaconase
FOG69_RS16155	COG2205	protein histidine kinase activity
FOG69_RS16160	COG0745	RESPONSE REGULATOR receiver
FOG69_RS16170	COG1191	sigma factor activity
FOG69_RS16180	COG2140	Oxalate decarboxylase
FOG69_RS16190	COG1120	ATPase activity
FOG69_RS16195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS16200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS16205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_RS16210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOG69_RS16215	COG0531	amino acid
FOG69_RS16230	COG1988	membrane-bound metal-dependent
FOG69_RS16235	COG1368	sulfuric ester hydrolase activity
FOG69_RS16240	COG1910	domain protein
FOG69_RS16245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOG69_RS16250	COG4149	molybdate abc transporter
FOG69_RS16255	COG2197	response regulator
FOG69_RS16265	COG1131	(ABC) transporter
FOG69_RS16275	COG0842	Transport permease protein
FOG69_RS16280	COG0656	L-ascorbic acid biosynthetic process
FOG69_RS16305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOG69_RS16310	COG3973	AAA domain
FOG69_RS16315	COG2860	membrane
FOG69_RS16325	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOG69_RS16330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOG69_RS16335	COG2217	Heavy metal translocating P-type atpase
FOG69_RS16340	COG2217	Heavy metal translocating P-type atpase
FOG69_RS16345	COG2608	mercury ion transmembrane transporter activity
FOG69_RS16350	COG1937	Protein conserved in bacteria
FOG69_RS16355	COG0673	inositol 2-dehydrogenase activity
FOG69_RS16365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS16370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOG69_RS16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS16380	COG1126	abc transporter atp-binding protein
FOG69_RS16385	COG0765	amino acid transport
FOG69_RS16390	COG0765	amino acid transport
FOG69_RS16395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS16400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOG69_RS16405	COG0454	-acetyltransferase
FOG69_RS16410	COG0583	DNA-binding transcription factor activity
FOG69_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS16420	COG2732	(Barnase) inhibitor
FOG69_RS16435	COG0557	exoribonuclease II activity
FOG69_RS16440	COG1647	Serine aminopeptidase, S33
FOG69_RS16445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOG69_RS16450	COG1476	TRANSCRIPTIONal
FOG69_RS16455	COG1396	sequence-specific DNA binding
FOG69_RS16460	COG1396	sequence-specific DNA binding
FOG69_RS16465	COG1733	regulation of RNA biosynthetic process
FOG69_RS16490	COG1131	(ABC) transporter
FOG69_RS16495	COG1174	glycine betaine transport
FOG69_RS16500	COG1732	Glycine betaine
FOG69_RS16505	COG1174	glycine betaine transport
FOG69_RS16510	COG1125	glycine betaine transport
FOG69_RS16510	COG0517	IMP dehydrogenase activity
FOG69_RS16515	COG1510	regulation of RNA biosynthetic process
FOG69_RS16520	COG1174	glycine betaine transport
FOG69_RS16525	COG1732	Glycine betaine
FOG69_RS16530	COG1174	glycine betaine transport
FOG69_RS16535	COG1125	glycine betaine transport
FOG69_RS16535	COG0517	IMP dehydrogenase activity
FOG69_RS16540	COG1510	regulation of RNA biosynthetic process
FOG69_RS16545	COG2095	MarC family integral membrane protein
FOG69_RS16550	COG3064	Membrane
FOG69_RS16560	COG0456	acetyltransferase
FOG69_RS16575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOG69_RS16595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOG69_RS16600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_RS16610	COG2234	aminopeptidase activity
FOG69_RS16630	COG0126	phosphoglycerate kinase activity
FOG69_RS16640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOG69_RS16645	COG2390	Transcriptional regulator
FOG69_RS16650	COG2814	Major facilitator Superfamily
FOG69_RS16655	COG1609	Transcriptional regulator
FOG69_RS16660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS16665	COG0583	DNA-binding transcription factor activity
FOG69_RS16670	COG0697	spore germination
FOG69_RS16675	COG1113	amino acid transport
FOG69_RS16680	COG1737	Transcriptional regulator
FOG69_RS16685	COG1070	Carbohydrate kinase
FOG69_RS16710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS16715	COG2186	Transcriptional regulator
FOG69_RS16720	COG1620	l-lactate permease
FOG69_RS16725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOG69_RS16735	COG5039	Polysaccharide pyruvyl transferase
FOG69_RS16740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_RS16745	COG0110	maltose O-acetyltransferase activity
FOG69_RS16750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOG69_RS16755	COG2244	polysaccharide biosynthetic process
FOG69_RS16760	COG1216	Glycosyl transferase, family 2
FOG69_RS16765	COG5039	Polysaccharide pyruvyl transferase
FOG69_RS16770	COG1216	Glycosyl transferase, family 2
FOG69_RS16780	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS16785	COG1215	transferase activity, transferring glycosyl groups
FOG69_RS16790	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS16795	COG1086	Polysaccharide biosynthesis protein
FOG69_RS16800	COG0489	protein tyrosine kinase activity
FOG69_RS16805	COG3944	biosynthesis protein
FOG69_RS16810	COG1396	sequence-specific DNA binding
FOG69_RS16815	COG2272	Belongs to the type-B carboxylesterase lipase family
FOG69_RS16825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOG69_RS16840	COG2364	Membrane
FOG69_RS16845	COG0456	acetyltransferase
FOG69_RS16850	COG3479	Phenolic acid decarboxylase
FOG69_RS16900	COG2223	nitrite transmembrane transporter activity
FOG69_RS16905	COG1609	Transcriptional regulator
FOG69_RS16915	COG0583	DNA-binding transcription factor activity
FOG69_RS16920	COG2828	Protein conserved in bacteria
FOG69_RS16925	COG2814	Major facilitator Superfamily
FOG69_RS16925	COG0477	Major facilitator Superfamily
FOG69_RS16935	COG1611	Belongs to the LOG family
FOG69_RS16940	COG1694	Mazg nucleotide pyrophosphohydrolase
FOG69_RS16945	COG0659	secondary active sulfate transmembrane transporter activity
FOG69_RS16950	COG0288	reversible hydration of carbon dioxide
FOG69_RS16960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOG69_RS16965	COG4290	ribonuclease
FOG69_RS16970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOG69_RS16975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS16985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOG69_RS16995	COG1051	belongs to the nudix hydrolase family
FOG69_RS17000	COG0492	ferredoxin-NADP+ reductase activity
FOG69_RS17005	COG3883	PFAM NLP P60 protein
FOG69_RS17005	COG0791	NLP P60 protein
FOG69_RS17010	COG0457	Tetratricopeptide repeat
FOG69_RS17015	COG5002	protein histidine kinase activity
FOG69_RS17020	COG0745	RESPONSE REGULATOR receiver
FOG69_RS17025	COG1132	(ABC) transporter
FOG69_RS17030	COG0140	phosphoribosyl-ATP diphosphatase activity
FOG69_RS17030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOG69_RS17055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOG69_RS17070	COG4990	cell redox homeostasis
FOG69_RS17075	COG0110	maltose O-acetyltransferase activity
FOG69_RS17095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOG69_RS17105	COG2188	Transcriptional regulator
FOG69_RS17110	COG1309	transcriptional regulator
FOG69_RS17115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOG69_RS17120	COG1950	PFAM Membrane protein of
FOG69_RS17125	COG1983	PspC domain protein
FOG69_RS17130	COG3595	metallopeptidase activity
FOG69_RS17145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOG69_RS17155	COG4897	Protein conserved in bacteria
FOG69_RS17160	COG0574	Belongs to the PEP-utilizing enzyme family
FOG69_RS17160	COG3848	Pyruvate phosphate dikinase
FOG69_RS17165	COG1309	transcriptional regulator
FOG69_RS17170	COG2814	Major facilitator Superfamily
FOG69_RS17185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_RS17195	COG0793	Belongs to the peptidase S41A family
FOG69_RS17195	COG3409	Peptidoglycan-binding domain 1 protein
FOG69_RS17200	COG3420	alginic acid biosynthetic process
FOG69_RS17205	COG2177	Part of the ABC transporter FtsEX involved in
FOG69_RS17210	COG2884	Cell division ATP-binding protein ftsE
FOG69_RS17215	COG2010	Cytochrome c
FOG69_RS17220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS17235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOG69_RS17250	COG1516	flagellar protein fliS
FOG69_RS17255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOG69_RS17260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOG69_RS17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOG69_RS17285	COG1256	bacterial-type flagellum assembly
FOG69_RS17285	COG4786	Flagellar basal body rod
FOG69_RS17290	COG3418	PFAM FlgN family protein
FOG69_RS17295	COG2747	anti-sigma28 factor FlgM
FOG69_RS17305	COG1040	competence protein
FOG69_RS17315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOG69_RS17320	COG1307	EDD domain protein, DegV family
FOG69_RS17325	COG2197	response regulator
FOG69_RS17330	COG4585	Histidine kinase
FOG69_RS17335	COG1739	Uncharacterized protein family UPF0029
FOG69_RS17340	COG1316	TRANSCRIPTIONal
FOG69_RS17345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOG69_RS17350	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS17355	COG1215	transferase activity, transferring glycosyl groups
FOG69_RS17360	COG3206	protein involved in exopolysaccharide biosynthesis
FOG69_RS17365	COG3307	-O-antigen
FOG69_RS17370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOG69_RS17375	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS17375	COG0297	glycogen (starch) synthase activity
FOG69_RS17380	COG2244	polysaccharide biosynthetic process
FOG69_RS17390	COG2247	cell wall binding repeat
FOG69_RS17390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOG69_RS17395	COG2247	cell wall binding repeat
FOG69_RS17395	COG2385	sporulation resulting in formation of a cellular spore
FOG69_RS17405	COG1316	TRANSCRIPTIONal
FOG69_RS17410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOG69_RS17415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOG69_RS17420	COG1134	teichoic acid transport
FOG69_RS17425	COG1682	transport, permease protein
FOG69_RS17430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_RS17440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOG69_RS17445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOG69_RS17450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_RS17455	COG4193	domain, Protein
FOG69_RS17460	COG1482	cell wall glycoprotein biosynthetic process
FOG69_RS17465	COG0697	spore germination
FOG69_RS17470	COG0814	amino acid
FOG69_RS17485	COG1215	transferase activity, transferring glycosyl groups
FOG69_RS17490	COG2814	Major facilitator Superfamily
FOG69_RS17495	COG1316	TRANSCRIPTIONal
FOG69_RS17500	COG0561	phosphatase activity
FOG69_RS17505	COG2433	Pfam Transposase IS66
FOG69_RS17510	COG0791	NLP P60 protein
FOG69_RS17525	COG2843	Capsule synthesis protein
FOG69_RS17535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOG69_RS17545	COG0697	spore germination
FOG69_RS17550	COG0814	amino acid
FOG69_RS17560	COG1609	Transcriptional regulator
FOG69_RS17565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOG69_RS17575	COG1129	ABC transporter
FOG69_RS17580	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOG69_RS17585	COG1879	ABC-type sugar transport system periplasmic component
FOG69_RS17590	COG3103	Sh3 type 3 domain protein
FOG69_RS17595	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOG69_RS17600	COG3527	Alpha-acetolactate decarboxylase
FOG69_RS17605	COG0028	Belongs to the TPP enzyme family
FOG69_RS17610	COG0583	DNA-binding transcription factor activity
FOG69_RS17615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOG69_RS17630	COG5337	Spore coat protein CotH
FOG69_RS17640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOG69_RS17650	COG0405	Gamma-glutamyltransferase
FOG69_RS17655	COG1522	sequence-specific DNA binding
FOG69_RS17660	COG2059	Chromate
FOG69_RS17665	COG2059	Chromate
FOG69_RS17700	COG5444	nuclease activity
FOG69_RS17715	COG3878	Protein conserved in bacteria
FOG69_RS17720	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOG69_RS17725	COG4464	protein tyrosine phosphatase activity
FOG69_RS17730	COG0489	protein tyrosine kinase activity
FOG69_RS17735	COG3944	biosynthesis protein
FOG69_RS17750	COG4715	Zinc finger, swim domain protein
FOG69_RS17755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOG69_RS17760	COG0561	phosphatase activity
FOG69_RS17765	COG1349	DNA-binding transcription factor activity
FOG69_RS17770	COG0629	single-stranded DNA binding
FOG69_RS17795	COG0457	Tetratricopeptide repeat
FOG69_RS17800	COG4786	Flagellar basal body rod
FOG69_RS17805	COG4786	Flagellar basal body rod
FOG69_RS17810	COG1077	Cell shape determining protein MreB Mrl
FOG69_RS17815	COG1609	Transcriptional regulator
FOG69_RS17820	COG1846	Transcriptional regulator
FOG69_RS17825	COG2814	Major facilitator Superfamily
FOG69_RS17830	COG1953	Uracil, thiamine, allantoin
FOG69_RS17840	COG1335	isochorismatase
FOG69_RS17845	COG0004	ammonium transporteR
FOG69_RS17850	COG0347	Belongs to the P(II) protein family
FOG69_RS17855	COG0772	Belongs to the SEDS family
FOG69_RS17860	COG0671	phosphoesterase, PA-phosphatase related
FOG69_RS17870	COG0739	heme binding
FOG69_RS17875	COG1247	-acetyltransferase
FOG69_RS17890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_RS17905	COG2910	NAD(P)H-binding
FOG69_RS17910	COG1959	2 iron, 2 sulfur cluster binding
FOG69_RS17925	COG0831	urea catabolic process
FOG69_RS17930	COG3237	CsbD-like
FOG69_RS17935	COG1994	Peptidase M50
FOG69_RS17940	COG0457	Tetratricopeptide repeat
FOG69_RS17950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOG69_RS17955	COG2304	oxidoreductase activity
FOG69_RS17960	COG2304	oxidoreductase activity
FOG69_RS17965	COG2385	sporulation resulting in formation of a cellular spore
FOG69_RS17970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOG69_RS17980	COG4836	Membrane
FOG69_RS18050	COG0698	ribose 5-phosphate isomerase
FOG69_RS18055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOG69_RS18065	COG0009	L-threonylcarbamoyladenylate synthase
FOG69_RS18070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOG69_RS18090	COG2890	protein-(glutamine-N5) methyltransferase activity
FOG69_RS18095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOG69_RS18100	COG0346	lactoylglutathione lyase activity
FOG69_RS18105	COG0789	Transcriptional regulator
FOG69_RS18110	COG0679	Auxin Efflux Carrier
FOG69_RS18115	COG0281	malic enzyme
FOG69_RS18130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOG69_RS18135	COG1494	fructose-1,6-bisphosphatase
FOG69_RS18140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOG69_RS18150	COG0191	fructose-bisphosphate aldolase activity
FOG69_RS18155	COG2204	response regulator
FOG69_RS18160	COG4821	SIS domain
FOG69_RS18175	COG2181	nitrate reductase activity
FOG69_RS18175	COG0247	lactate metabolic process
FOG69_RS18180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_RS18195	COG1132	(ABC) transporter
FOG69_RS18200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOG69_RS18205	COG2181	nitrate reductase activity
FOG69_RS18210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOG69_RS18215	COG1140	nitrate reductase beta subunit
FOG69_RS18220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOG69_RS18225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_RS18235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOG69_RS18240	COG2223	nitrite transmembrane transporter activity
FOG69_RS18250	COG4506	Protein conserved in bacteria
FOG69_RS18260	COG3391	amine dehydrogenase activity
FOG69_RS18270	COG0457	Tetratricopeptide repeat
FOG69_RS18280	COG0010	Belongs to the arginase family
FOG69_RS18285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOG69_RS18290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOG69_RS18305	COG1994	Peptidase M50
FOG69_RS18310	COG1942	4-Oxalocrotonate Tautomerase
FOG69_RS18315	COG1846	Transcriptional regulator
FOG69_RS18325	COG0531	amino acid
FOG69_RS18330	COG3465	dGTPase activity
FOG69_RS18335	COG1078	dGTPase activity
FOG69_RS18350	COG1695	Transcriptional regulator
FOG69_RS18365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOG69_RS18395	COG0583	DNA-binding transcription factor activity
FOG69_RS18400	COG2855	membrane
FOG69_RS18405	COG0280	phosphate acetyltransferase
FOG69_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS18420	COG0436	Aminotransferase
FOG69_RS18430	COG0151	Belongs to the GarS family
FOG69_RS18440	COG1917	Cupin 2, conserved barrel domain protein
FOG69_RS18445	COG0077	Prephenate dehydratase
FOG69_RS18450	COG2814	Major facilitator Superfamily
FOG69_RS18455	COG2814	Major facilitator Superfamily
FOG69_RS18460	COG0833	amino acid
FOG69_RS18465	COG4187	Peptidase family M20/M25/M40
FOG69_RS18470	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS18475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOG69_RS18485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FOG69_RS18490	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOG69_RS18495	COG1088	dTDP-glucose 4,6-dehydratase activity
FOG69_RS18500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOG69_RS18505	COG3980	spore coat polysaccharide biosynthesis protein
FOG69_RS18510	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FOG69_RS18515	COG2089	acid synthase
FOG69_RS18520	COG0456	acetyltransferase
FOG69_RS18525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOG69_RS18530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOG69_RS18535	COG0463	Glycosyl transferase, family 2
FOG69_RS18545	COG2363	Small membrane protein
FOG69_RS18550	COG2233	PERMEase
FOG69_RS18565	COG1216	Glycosyl transferase, family 2
FOG69_RS18575	COG0351	phosphomethylpyrimidine kinase
FOG69_RS18585	COG1621	beta-fructofuranosidase activity
FOG69_RS18590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS18590	COG1263	PTS System
FOG69_RS18595	COG3711	transcriptional antiterminator
FOG69_RS18605	COG1404	Belongs to the peptidase S8 family
FOG69_RS18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOG69_RS18615	COG2378	regulation of single-species biofilm formation
FOG69_RS18635	COG0778	Nitroreductase
FOG69_RS18640	COG0772	Belongs to the SEDS family
FOG69_RS18645	COG0454	-acetyltransferase
FOG69_RS18665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOG69_RS18670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOG69_RS18675	COG2261	transglycosylase associated protein
FOG69_RS18680	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOG69_RS18685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOG69_RS18690	COG2246	polysaccharide biosynthetic process
FOG69_RS18695	COG1309	transcriptional regulator
FOG69_RS18715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOG69_RS18720	COG2837	iron assimilation
FOG69_RS18725	COG2822	iron ion transport
FOG69_RS18730	COG0672	)-iron permease
FOG69_RS18745	COG0583	DNA-binding transcription factor activity
FOG69_RS18755	COG1346	cytolysis
FOG69_RS18760	COG4895	conserved protein (DUF2196)
FOG69_RS18765	COG0789	Transcriptional regulator
FOG69_RS18770	COG5504	Zn-dependent protease
FOG69_RS18775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOG69_RS18780	COG0346	lactoylglutathione lyase activity
FOG69_RS18785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS18790	COG1404	Belongs to the peptidase S8 family
FOG69_RS18795	COG1442	glycosyl transferase family 8
FOG69_RS18800	COG2357	RelA SpoT domain protein
FOG69_RS18805	COG1575	Belongs to the MenA family. Type 1 subfamily
FOG69_RS18830	COG1696	Membrane protein involved in D-alanine export
FOG69_RS18840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOG69_RS18845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS18850	COG1486	melibiose metabolic process
FOG69_RS18855	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_RS18860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS18865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS18870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOG69_RS18870	COG3711	transcriptional antiterminator
FOG69_RS18885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS18890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOG69_RS18900	COG0640	Transcriptional regulator
FOG69_RS18905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOG69_RS18910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS18915	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOG69_RS18920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOG69_RS18925	COG2723	6-phospho-beta-galactosidase activity
FOG69_RS18930	COG1940	carbohydrate kinase activity
FOG69_RS18935	COG1482	cell wall glycoprotein biosynthetic process
FOG69_RS18945	COG0753	catalase activity
FOG69_RS18950	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOG69_RS18955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOG69_RS18960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOG69_RS18965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOG69_RS18970	COG4988	ABC transporter
FOG69_RS18975	COG1294	oxidase, subunit
FOG69_RS18980	COG1271	oxidase subunit
FOG69_RS18985	COG3493	citrate carrier protein
FOG69_RS18990	COG0726	polysaccharide deacetylase
FOG69_RS18995	COG3842	ATPase activity
FOG69_RS19000	COG2508	Transcriptional regulator
FOG69_RS19005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS19015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOG69_RS19025	COG4894	glucomannan catabolic process
FOG69_RS19030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOG69_RS19035	COG0500	methyltransferase
FOG69_RS19040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_RS19060	COG0693	protein deglycase activity
FOG69_RS19060	COG0753	catalase activity
FOG69_RS19065	COG2851	Citrate transporter
FOG69_RS19070	COG2273	Hydrolase Family 16
FOG69_RS19075	COG3711	transcriptional antiterminator
FOG69_RS19080	COG2270	Major facilitator Superfamily
FOG69_RS19085	COG0513	Belongs to the DEAD box helicase family
FOG69_RS19130	COG0697	spore germination
FOG69_RS19135	COG0589	response to stress
FOG69_RS19140	COG2723	6-phospho-beta-galactosidase activity
FOG69_RS19145	COG1263	PTS System
FOG69_RS19145	COG2190	(PTS) system
FOG69_RS19145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOG69_RS19160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOG69_RS19185	COG3507	Belongs to the glycosyl hydrolase 43 family
FOG69_RS19210	COG0010	Belongs to the arginase family
FOG69_RS19215	COG0833	amino acid
FOG69_RS19220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOG69_RS19225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOG69_RS19235	COG2390	Transcriptional regulator
FOG69_RS19240	COG0561	phosphatase activity
FOG69_RS19270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOG69_RS19275	COG5294	Protein conserved in bacteria
FOG69_RS19280	COG0577	efflux transmembrane transporter activity
FOG69_RS19285	COG1136	(ABC) transporter
FOG69_RS19290	COG2205	protein histidine kinase activity
FOG69_RS19295	COG0745	RESPONSE REGULATOR receiver
FOG69_RS19310	COG1082	Xylose isomerase domain protein TIM barrel
FOG69_RS19320	COG2814	Major facilitator Superfamily
FOG69_RS19350	COG1349	DNA-binding transcription factor activity
FOG69_RS19355	COG0667	Aldo Keto reductase
FOG69_RS19360	COG2814	Major facilitator Superfamily
FOG69_RS19370	COG1028	Short-chain dehydrogenase reductase Sdr
FOG69_RS19375	COG2197	response regulator
FOG69_RS19380	COG4585	Histidine kinase
FOG69_RS19385	COG3239	Fatty acid desaturase
FOG69_RS19395	COG1309	transcriptional regulator
FOG69_RS19400	COG1012	belongs to the aldehyde dehydrogenase family
FOG69_RS19405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOG69_RS19415	COG0640	Transcriptional regulator
FOG69_RS19420	COG2814	Major facilitator Superfamily
FOG69_RS19425	COG1714	RDD family
FOG69_RS19435	COG0450	alkyl hydroperoxide reductase
FOG69_RS19440	COG3634	alkyl hydroperoxide reductase activity
FOG69_RS19450	COG1113	amino acid transport
FOG69_RS19480	COG2080	2 iron, 2 sulfur cluster binding
FOG69_RS19490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOG69_RS19495	COG2068	MobA-Related Protein
FOG69_RS19500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOG69_RS19550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOG69_RS19555	COG0667	Aldo Keto reductase
FOG69_RS19560	COG0456	acetyltransferase
FOG69_RS19565	COG0457	Tetratricopeptide repeat
FOG69_RS19570	COG0010	Belongs to the arginase family
FOG69_RS19575	COG0833	amino acid
FOG69_RS19580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOG69_RS19585	COG5658	integral membrane protein
FOG69_RS19590	COG0640	Transcriptional regulator
FOG69_RS19595	COG3829	transcription factor binding
FOG69_RS19610	COG3850	Histidine kinase
FOG69_RS19610	COG5002	protein histidine kinase activity
FOG69_RS19615	COG0745	RESPONSE REGULATOR receiver
FOG69_RS19625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOG69_RS19630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOG69_RS19635	COG4853	Protein conserved in bacteria
FOG69_RS19640	COG4863	YycH protein
FOG69_RS19645	COG5002	protein histidine kinase activity
FOG69_RS19650	COG0745	RESPONSE REGULATOR receiver
FOG69_RS19685	COG0346	lactoylglutathione lyase activity
FOG69_RS19690	COG0305	Participates in initiation and elongation during chromosome replication
FOG69_RS19705	COG3093	addiction module antidote protein HigA
FOG69_RS19725	COG0438	transferase activity, transferring glycosyl groups
FOG69_RS19745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOG69_RS19750	COG4241	membrane
FOG69_RS19760	COG5577	PFAM Coat F domain
FOG69_RS19765	COG1733	regulation of RNA biosynthetic process
FOG69_RS19775	COG0697	spore germination
FOG69_RS19780	COG1621	beta-fructofuranosidase activity
FOG69_RS19785	COG1621	beta-fructofuranosidase activity
FOG69_RS19795	COG2318	DinB family
FOG69_RS19800	COG2211	Major facilitator Superfamily
FOG69_RS19815	COG0778	Nitroreductase
FOG69_RS19820	COG1846	Transcriptional regulator
FOG69_RS19825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOG69_RS19830	COG1846	Transcriptional regulator
FOG69_RS19835	COG2153	protein acetylation
FOG69_RS19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOG69_RS19850	COG0697	spore germination
FOG69_RS19855	COG1331	Highly conserved protein containing a thioredoxin domain
FOG69_RS19865	COG1331	Highly conserved protein containing a thioredoxin domain
FOG69_RS19870	COG1266	CAAX protease self-immunity
FOG69_RS19875	COG0477	Major facilitator Superfamily
FOG69_RS19875	COG2814	Major facilitator Superfamily
FOG69_RS19880	COG0346	lactoylglutathione lyase activity
FOG69_RS19885	COG1609	Transcriptional regulator
FOG69_RS19890	COG0708	Exodeoxyribonuclease III
FOG69_RS19895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOG69_RS19900	COG2169	Transcriptional regulator
FOG69_RS19910	COG0629	single-stranded DNA binding
FOG69_RS19920	COG0012	GTP binding
FOG69_RS19925	COG0243	molybdopterin cofactor binding
FOG69_RS19930	COG4481	Protein conserved in bacteria
FOG69_RS19935	COG3949	Membrane
FOG69_RS19950	COG1475	DNA binding
FOG69_RS19955	COG1192	Involved in chromosome partitioning
FOG69_RS19980	COG1847	R3H domain protein
FOG69_RS19985	COG0706	membrane insertase activity
FOG69_RS20005	COG0592	DNA-directed DNA polymerase activity
FOG69_RS20010	COG2501	S4 domain
FOG69_RS20025	COG0187	DNA topoisomerase II activity
FOG69_RS20030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOG69_RS20065	COG0517	IMP dehydrogenase activity
FOG69_RS20065	COG0516	GMP reductase activity
FOG69_RS20070	COG1686	Belongs to the peptidase S11 family
FOG69_RS20090	COG1929	Belongs to the glycerate kinase type-1 family
FOG69_RS20100	COG1428	Deoxynucleoside kinase
FOG69_RS20105	COG1428	Deoxynucleoside kinase
FOG69_RS20110	COG1388	LysM domain
FOG69_RS20110	COG3858	chitin binding
FOG69_RS20115	COG1335	isochorismatase
FOG69_RS20120	COG0590	tRNA wobble adenosine to inosine editing
FOG69_RS20130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOG69_RS20135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOG69_RS20185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FOG69_RS20190	COG3853	Toxic anion resistance protein (TelA)
FOG69_RS20195	COG1982	Orn Lys Arg decarboxylase major
FOG69_RS20205	COG3870	Protein conserved in bacteria
FOG69_RS20210	COG1728	Protein conserved in bacteria
FOG69_RS20215	COG0470	DNA polymerase III
FOG69_RS20220	COG1774	PSP1 C-terminal conserved region
FOG69_RS20230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOG69_RS20240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOG69_RS20245	COG2002	toxin-antitoxin pair type II binding
FOG69_RS20250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_RS20250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOG69_RS20255	COG0084	hydrolase, TatD family'
FOG69_RS20260	COG3584	3D domain protein
FOG69_RS20260	COG3583	domain protein
FOG69_RS20265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOG69_RS20270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOG69_RS20280	COG4466	Protein conserved in bacteria
FOG69_RS20295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOG69_RS20300	COG0251	oxidation-reduction process
FOG69_RS20315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOG69_RS20335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOG69_RS20340	COG2002	toxin-antitoxin pair type II binding
FOG69_RS20345	COG2244	polysaccharide biosynthetic process
FOG69_RS20350	COG3956	TIGRFAM MazG family protein
FOG69_RS20355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOG69_RS20370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOG69_RS20375	COG1098	S1 RNA binding domain
FOG69_RS20390	COG2208	phosphoserine phosphatase activity
FOG69_RS20395	COG2304	oxidoreductase activity
FOG69_RS20400	COG0515	serine threonine protein kinase
FOG69_RS20405	COG0037	tRNA processing
FOG69_RS20410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOG69_RS20415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOG69_RS20430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOG69_RS20435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOG69_RS20440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOG69_RS20445	COG0512	Glutamine amidotransferase of anthranilate synthase
FOG69_RS20450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOG69_RS20455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOG69_RS20460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOG69_RS20465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOG69_RS20470	COG1396	sequence-specific DNA binding
FOG69_RS20475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOG69_RS20480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family