locus-tag	class	description
BUN12_RS00015	COG0305	Participates in initiation and elongation during chromosome replication
BUN12_RS00040	COG1595	DNA-templated transcription, initiation
BUN12_RS00085	COG0740	serine-type endopeptidase activity
BUN12_RS00195	COG1194	a g-specific adenine glycosylase
BUN12_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS00225	COG1132	(ABC) transporter
BUN12_RS00230	COG4129	membrane
BUN12_RS00240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BUN12_RS00245	COG0735	belongs to the Fur family
BUN12_RS00350	COG4974	Belongs to the 'phage' integrase family
BUN12_RS00410	COG1484	DNA-dependent DNA replication
BUN12_RS00435	COG3655	Transcriptional regulator
BUN12_RS00470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS00470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS00510	COG1780	Probably involved in ribonucleotide reductase function
BUN12_RS00515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_RS00530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_RS00535	COG0756	dUTP diphosphatase activity
BUN12_RS00545	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BUN12_RS00580	COG1595	DNA-templated transcription, initiation
BUN12_RS00595	COG1793	dna ligase
BUN12_RS00640	COG0582	viral genome integration into host DNA
BUN12_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_RS00740	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS00765	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS00765	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS00765	COG1388	LysM domain
BUN12_RS00805	COG3340	Belongs to the peptidase S51 family
BUN12_RS00815	COG0277	FAD linked oxidase domain protein
BUN12_RS00825	COG0747	negative chemotaxis
BUN12_RS00830	COG0601	transmembrane transport
BUN12_RS00835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_RS00840	COG0444	Belongs to the ABC transporter superfamily
BUN12_RS00850	COG0753	catalase activity
BUN12_RS00860	COG1116	anion transmembrane transporter activity
BUN12_RS00865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUN12_RS00870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUN12_RS00895	COG1476	TRANSCRIPTIONal
BUN12_RS00905	COG3382	B3 4 domain protein
BUN12_RS00910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BUN12_RS00920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BUN12_RS00925	COG0789	Transcriptional regulator
BUN12_RS00930	COG1664	Polymer-forming cytoskeletal
BUN12_RS00935	COG1664	Polymer-forming cytoskeletal
BUN12_RS00945	COG2766	serine protein kinase
BUN12_RS00955	COG1846	Transcriptional regulator
BUN12_RS00960	COG1566	PFAM secretion protein HlyD family protein
BUN12_RS00965	COG2814	Major facilitator Superfamily
BUN12_RS00970	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUN12_RS00985	COG1725	Transcriptional regulator
BUN12_RS00990	COG1131	(ABC) transporter
BUN12_RS00995	COG1131	(ABC) transporter
BUN12_RS01000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_RS01005	COG1278	Cold shock
BUN12_RS01010	COG1464	Belongs to the NlpA lipoprotein family
BUN12_RS01015	COG3706	GGDEF domain
BUN12_RS01020	COG1823	symporter activity
BUN12_RS01025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_RS01045	COG5577	PFAM Coat F domain
BUN12_RS01050	COG4085	toxin activity
BUN12_RS01050	COG0737	Belongs to the 5'-nucleotidase family
BUN12_RS01050	COG1525	nuclease
BUN12_RS01055	COG3764	Sortase (surface protein transpeptidase)
BUN12_RS01060	COG0564	pseudouridine synthase activity
BUN12_RS01070	COG0517	IMP dehydrogenase activity
BUN12_RS01075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUN12_RS01080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN12_RS01080	COG3153	acetyltransferase
BUN12_RS01085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_RS01090	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUN12_RS01095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUN12_RS01105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BUN12_RS01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUN12_RS01115	COG2203	Gaf domain
BUN12_RS01115	COG4585	Histidine kinase
BUN12_RS01120	COG2197	response regulator
BUN12_RS01125	COG0431	NADPH-dependent FMN reductase
BUN12_RS01140	COG0791	NLP P60 protein
BUN12_RS01140	COG1388	LysM domain
BUN12_RS01145	COG1959	2 iron, 2 sulfur cluster binding
BUN12_RS01150	COG0668	transmembrane transport
BUN12_RS01155	COG2719	SpoVR family
BUN12_RS01160	COG1785	Belongs to the alkaline phosphatase family
BUN12_RS01165	COG0791	NLP P60 protein
BUN12_RS01165	COG1388	LysM domain
BUN12_RS01170	COG0583	DNA-binding transcription factor activity
BUN12_RS01175	COG0372	Belongs to the citrate synthase family
BUN12_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS01185	COG0531	amino acid
BUN12_RS01190	COG0733	neurotransmitter:sodium symporter activity
BUN12_RS01205	COG1595	DNA-templated transcription, initiation
BUN12_RS01210	COG0204	Acyl-transferase
BUN12_RS01215	COG1253	flavin adenine dinucleotide binding
BUN12_RS01220	COG0789	Transcriptional regulator
BUN12_RS01225	COG0436	Aminotransferase
BUN12_RS01230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_RS01235	COG1253	flavin adenine dinucleotide binding
BUN12_RS01240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUN12_RS01245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUN12_RS01250	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_RS01260	COG0668	transmembrane transport
BUN12_RS01265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BUN12_RS01270	COG0726	polysaccharide deacetylase
BUN12_RS01275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS01280	COG3226	Transcriptional regulator
BUN12_RS01290	COG0589	response to stress
BUN12_RS01295	COG1132	(ABC) transporter
BUN12_RS01300	COG1132	(ABC) transporter
BUN12_RS01305	COG0702	epimerase
BUN12_RS01320	COG0189	ligase activity
BUN12_RS01325	COG0189	ligase activity
BUN12_RS01340	COG0561	phosphatase activity
BUN12_RS01345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN12_RS01355	COG0475	glutathione-regulated potassium exporter activity
BUN12_RS01360	COG0490	domain, Protein
BUN12_RS01370	COG1024	Enoyl-CoA hydratase
BUN12_RS01380	COG4152	abc transporter atp-binding protein
BUN12_RS01385	COG1668	transmembrane transport
BUN12_RS01390	COG0420	3'-5' exonuclease activity
BUN12_RS01395	COG4717	serine-type aminopeptidase activity
BUN12_RS01410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUN12_RS01450	COG4980	gas vesicle protein
BUN12_RS01465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BUN12_RS01470	COG0537	adenosine 5'-monophosphoramidase activity
BUN12_RS01475	COG1131	(ABC) transporter
BUN12_RS01480	COG4473	ABC transporter
BUN12_RS01490	COG1473	amidohydrolase
BUN12_RS01495	COG3069	C4-dicarboxylate transmembrane transporter activity
BUN12_RS01500	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_RS01505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_RS01515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BUN12_RS01520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BUN12_RS01525	COG1309	transcriptional regulator
BUN12_RS01530	COG1511	domain protein
BUN12_RS01535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS01545	COG1363	Peptidase, m42
BUN12_RS01550	COG1301	dicarboxylic acid transport
BUN12_RS01560	COG1234	tRNA 3'-trailer cleavage
BUN12_RS01565	COG0095	Lipoate-protein ligase
BUN12_RS01570	COG0702	epimerase
BUN12_RS01575	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_RS01585	COG0501	Belongs to the peptidase M48B family
BUN12_RS01590	COG1404	Belongs to the peptidase S8 family
BUN12_RS01600	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BUN12_RS01605	COG0406	alpha-ribazole phosphatase activity
BUN12_RS01610	COG0183	Belongs to the thiolase family
BUN12_RS01620	COG1268	BioY protein
BUN12_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS01645	COG4903	ComK protein
BUN12_RS01650	COG5646	InterPro IPR014922
BUN12_RS01675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_RS01690	COG0398	Pfam SNARE associated Golgi protein
BUN12_RS01695	COG0681	Belongs to the peptidase S26 family
BUN12_RS01700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BUN12_RS01705	COG1846	Transcriptional regulator
BUN12_RS01710	COG3180	Ammonia monooxygenase
BUN12_RS01715	COG2814	Major facilitator Superfamily
BUN12_RS01725	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BUN12_RS01730	COG2323	membrane
BUN12_RS01745	COG0420	3'-5' exonuclease activity
BUN12_RS01750	COG0419	ATPase involved in DNA repair
BUN12_RS01755	COG1403	HNH endonuclease
BUN12_RS01795	COG0179	Fumarylacetoacetate (FAA) hydrolase
BUN12_RS01805	COG1404	Belongs to the peptidase S8 family
BUN12_RS01815	COG0367	asparagine synthase
BUN12_RS01820	COG1562	ergosterol biosynthetic process
BUN12_RS01825	COG0534	Mate efflux family protein
BUN12_RS01830	COG2207	Transcriptional regulator
BUN12_RS01830	COG1917	Cupin 2, conserved barrel domain protein
BUN12_RS01835	COG1609	Transcriptional regulator
BUN12_RS01840	COG0673	inositol 2-dehydrogenase activity
BUN12_RS01845	COG2318	DinB family
BUN12_RS01850	COG1279	arginine transmembrane transporter activity
BUN12_RS01855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS01860	COG1357	PFAM Pentapeptide repeats (8 copies)
BUN12_RS01865	COG2153	protein acetylation
BUN12_RS01870	COG0646	methionine synthase
BUN12_RS01870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BUN12_RS01880	COG2996	Protein conserved in bacteria
BUN12_RS01885	COG1744	ABC transporter substrate-binding protein PnrA-like
BUN12_RS01890	COG0840	transmembrane signaling receptor activity
BUN12_RS01905	COG1307	EDD domain protein, DegV family
BUN12_RS01910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS01925	COG0561	phosphatase activity
BUN12_RS01930	COG1073	alpha beta
BUN12_RS01935	COG2151	metal-sulfur cluster biosynthetic enzyme
BUN12_RS01945	COG0277	FAD linked oxidase domain protein
BUN12_RS01950	COG2271	Major facilitator Superfamily
BUN12_RS01960	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BUN12_RS01970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUN12_RS01975	COG0505	Belongs to the CarA family
BUN12_RS01980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN12_RS01985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BUN12_RS02005	COG2267	carboxylic ester hydrolase activity
BUN12_RS02015	COG1744	ABC transporter substrate-binding protein PnrA-like
BUN12_RS02030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS02035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_RS02040	COG5504	Zn-dependent protease
BUN12_RS02045	COG0444	Belongs to the ABC transporter superfamily
BUN12_RS02050	COG4608	Belongs to the ABC transporter superfamily
BUN12_RS02060	COG0601	transmembrane transport
BUN12_RS02065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_RS02075	COG0180	Tryptophanyl-tRNA synthetase
BUN12_RS02085	COG4166	transmembrane transport
BUN12_RS02090	COG0601	transmembrane transport
BUN12_RS02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_RS02100	COG0444	Belongs to the ABC transporter superfamily
BUN12_RS02105	COG4608	Belongs to the ABC transporter superfamily
BUN12_RS02115	COG0456	acetyltransferase
BUN12_RS02120	COG1393	Belongs to the ArsC family
BUN12_RS02125	COG0861	Integral membrane protein TerC family
BUN12_RS02130	COG4862	establishment of competence for transformation
BUN12_RS02135	COG4469	Competence protein
BUN12_RS02140	COG1164	Oligoendopeptidase f
BUN12_RS02145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUN12_RS02150	COG2346	COG2346, Truncated hemoglobins
BUN12_RS02155	COG0741	lytic transglycosylase activity
BUN12_RS02160	COG4116	CYTH
BUN12_RS02170	COG2357	RelA SpoT domain protein
BUN12_RS02175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUN12_RS02180	COG0564	pseudouridine synthase activity
BUN12_RS02195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUN12_RS02200	COG0352	thiamine-phosphate diphosphorylase activity
BUN12_RS02205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN12_RS02210	COG2104	thiamine diphosphate biosynthetic process
BUN12_RS02220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUN12_RS02225	COG0351	phosphomethylpyrimidine kinase
BUN12_RS02230	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BUN12_RS02285	COG0210	DNA helicase
BUN12_RS02295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS02305	COG1131	(ABC) transporter
BUN12_RS02315	COG2153	protein acetylation
BUN12_RS02325	COG2382	esterase
BUN12_RS02330	COG0626	cystathionine gamma-synthase activity
BUN12_RS02335	COG0626	cystathionine gamma-synthase activity
BUN12_RS02355	COG0582	viral genome integration into host DNA
BUN12_RS02365	COG4282	regulation of fungal-type cell wall biogenesis
BUN12_RS02410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_RS02465	COG2367	Beta-lactamase
BUN12_RS02470	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BUN12_RS02475	COG0477	Major facilitator Superfamily
BUN12_RS02480	COG1846	Transcriptional regulator
BUN12_RS02495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS02495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS02500	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_RS02505	COG2723	6-phospho-beta-galactosidase activity
BUN12_RS02510	COG1349	DNA-binding transcription factor activity
BUN12_RS02530	COG1285	pathogenesis
BUN12_RS02540	COG2205	protein histidine kinase activity
BUN12_RS02560	COG0390	transport system, permease component
BUN12_RS02565	COG1587	Uroporphyrinogen-III synthase
BUN12_RS02575	COG1819	glycosyl
BUN12_RS02580	COG2124	cytochrome p450
BUN12_RS02585	COG2427	Protein of unknown function (DUF1641)
BUN12_RS02600	COG0697	spore germination
BUN12_RS02605	COG4297	protein containing double-stranded beta helix domain
BUN12_RS02615	COG1252	NADH dehydrogenase
BUN12_RS02625	COG1609	Transcriptional regulator
BUN12_RS02635	COG0745	RESPONSE REGULATOR receiver
BUN12_RS02640	COG5002	protein histidine kinase activity
BUN12_RS02655	COG0730	response to heat
BUN12_RS02660	COG2318	DinB family
BUN12_RS02670	COG0457	Tetratricopeptide repeat
BUN12_RS02675	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS02675	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS02675	COG1388	LysM domain
BUN12_RS02685	COG4195	phage-related replication protein
BUN12_RS02690	COG2856	Zn peptidase
BUN12_RS02695	COG1396	sequence-specific DNA binding
BUN12_RS02705	COG1522	sequence-specific DNA binding
BUN12_RS02710	COG1484	DNA-dependent DNA replication
BUN12_RS02725	COG1595	DNA-templated transcription, initiation
BUN12_RS02730	COG3728	DNA packaging
BUN12_RS02730	COG5484	DNA packaging
BUN12_RS02735	COG1783	phage Terminase large subunit
BUN12_RS02740	COG5518	Phage portal protein
BUN12_RS02745	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BUN12_RS02750	COG4653	Phage capsid family
BUN12_RS02800	COG3953	SLT domain
BUN12_RS02800	COG5412	phage tail tape measure protein
BUN12_RS02800	COG5412	phage tail tape measure protein
BUN12_RS02800	COG5412	phage tail tape measure protein
BUN12_RS02800	COG3953	SLT domain
BUN12_RS02800	COG3953	SLT domain
BUN12_RS02805	COG1652	LysM domain
BUN12_RS02810	COG4193	domain, Protein
BUN12_RS02820	COG3628	GPW Gp25 family protein
BUN12_RS02825	COG3299	homolog of phage Mu protein gp47
BUN12_RS02830	COG3778	Protein conserved in bacteria
BUN12_RS02875	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS02875	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS02890	COG0306	phosphate transporter
BUN12_RS02895	COG1392	Phosphate transport regulator
BUN12_RS02900	COG0531	amino acid
BUN12_RS02905	COG0346	lactoylglutathione lyase activity
BUN12_RS02910	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BUN12_RS02915	COG0463	Glycosyl transferase, family 2
BUN12_RS02920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_RS02925	COG0477	Major facilitator Superfamily
BUN12_RS02930	COG2362	D-Aminopeptidase
BUN12_RS02935	COG0601	transmembrane transport
BUN12_RS02940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUN12_RS02945	COG0444	Belongs to the ABC transporter superfamily
BUN12_RS02950	COG4166	transmembrane transport
BUN12_RS02955	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUN12_RS02960	COG4948	Mandelate Racemase Muconate Lactonizing
BUN12_RS02965	COG0791	NLP P60 protein
BUN12_RS02970	COG4608	Belongs to the ABC transporter superfamily
BUN12_RS02975	COG2706	6-phosphogluconolactonase activity
BUN12_RS02980	COG1834	amidinotransferase
BUN12_RS02985	COG1607	acyl-coa hydrolase
BUN12_RS02990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_RS02995	COG2076	Multidrug Resistance protein
BUN12_RS03000	COG2076	Multidrug Resistance protein
BUN12_RS03005	COG0788	formyltetrahydrofolate deformylase activity
BUN12_RS03010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUN12_RS03020	COG1764	response to oxidative stress
BUN12_RS03025	COG1846	Transcriptional regulator
BUN12_RS03030	COG1764	response to oxidative stress
BUN12_RS03045	COG0457	Tetratricopeptide repeat
BUN12_RS03045	COG0463	Glycosyl transferase, family 2
BUN12_RS03060	COG2814	Major facilitator Superfamily
BUN12_RS03065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_RS03075	COG1404	Belongs to the peptidase S8 family
BUN12_RS03080	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS03085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUN12_RS03090	COG1122	ATPase activity
BUN12_RS03095	COG4721	ABC-type cobalt transport system, permease component
BUN12_RS03100	COG1388	LysM domain
BUN12_RS03100	COG3858	chitin binding
BUN12_RS03115	COG2239	Acts as a magnesium transporter
BUN12_RS03120	COG0789	Transcriptional regulator
BUN12_RS03135	COG1846	Transcriptional regulator
BUN12_RS03140	COG0726	polysaccharide deacetylase
BUN12_RS03145	COG3285	dna ligase
BUN12_RS03145	COG1793	dna ligase
BUN12_RS03150	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BUN12_RS03155	COG5001	Diguanylate cyclase
BUN12_RS03155	COG3300	MHYT domain
BUN12_RS03160	COG0586	Pfam SNARE associated Golgi protein
BUN12_RS03165	COG0861	Integral membrane protein TerC family
BUN12_RS03170	COG1191	sigma factor activity
BUN12_RS03195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUN12_RS03200	COG2323	membrane
BUN12_RS03210	COG3594	Acyltransferase
BUN12_RS03215	COG5002	protein histidine kinase activity
BUN12_RS03220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUN12_RS03235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN12_RS03240	COG0436	Aminotransferase
BUN12_RS03275	COG3852	Histidine kinase
BUN12_RS03280	COG1846	Transcriptional regulator
BUN12_RS03285	COG1360	Flagellar Motor Protein
BUN12_RS03290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUN12_RS03295	COG0542	response to heat
BUN12_RS03305	COG3949	Membrane
BUN12_RS03320	COG0720	synthase
BUN12_RS03325	COG0602	queuosine metabolic process
BUN12_RS03340	COG4873	Protein conserved in bacteria
BUN12_RS03350	COG3773	Cell wall hydrolase
BUN12_RS03355	COG2244	polysaccharide biosynthetic process
BUN12_RS03360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS03365	COG2217	Heavy metal translocating P-type atpase
BUN12_RS03370	COG0006	proline dipeptidase activity
BUN12_RS03375	COG1609	Transcriptional regulator
BUN12_RS03380	COG3711	transcriptional antiterminator
BUN12_RS03385	COG2190	(PTS) system
BUN12_RS03385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS03385	COG1263	PTS System
BUN12_RS03390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS03395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BUN12_RS03405	COG1533	DNA photolyase activity
BUN12_RS03410	COG0840	transmembrane signaling receptor activity
BUN12_RS03415	COG2084	Dehydrogenase
BUN12_RS03425	COG2340	Cysteine-rich secretory protein family
BUN12_RS03430	COG0768	penicillin binding
BUN12_RS03435	COG4191	Histidine kinase
BUN12_RS03440	COG0436	Aminotransferase
BUN12_RS03450	COG0784	Response regulator, receiver
BUN12_RS03450	COG0835	chemotaxis
BUN12_RS03460	COG2814	Major facilitator Superfamily
BUN12_RS03465	COG1376	ErfK ybiS ycfS ynhG family protein
BUN12_RS03470	COG1408	metallophosphoesterase
BUN12_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS03485	COG2200	EAL domain
BUN12_RS03490	COG4703	Protein of unknown function (DUF1797)
BUN12_RS03495	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BUN12_RS03505	COG0517	IMP dehydrogenase activity
BUN12_RS03510	COG0583	DNA-binding transcription factor activity
BUN12_RS03515	COG0716	FMN binding
BUN12_RS03525	COG0716	FMN binding
BUN12_RS03545	COG0668	transmembrane transport
BUN12_RS03575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUN12_RS03580	COG0303	'Molybdopterin
BUN12_RS03585	COG1763	Mo-molybdopterin cofactor biosynthetic process
BUN12_RS03590	COG0314	molybdopterin synthase activity
BUN12_RS03595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BUN12_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN12_RS03610	COG1136	(ABC) transporter
BUN12_RS03615	COG0577	efflux transmembrane transporter activity
BUN12_RS03620	COG1349	DNA-binding transcription factor activity
BUN12_RS03625	COG1105	Belongs to the carbohydrate kinase PfkB family
BUN12_RS03630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_RS03630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS03630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_RS03635	COG0681	Belongs to the peptidase S26 family
BUN12_RS03645	COG0488	(ABC) transporter
BUN12_RS03650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUN12_RS03655	COG2309	aminopeptidase activity
BUN12_RS03665	COG1077	Cell shape determining protein MreB Mrl
BUN12_RS03675	COG2002	toxin-antitoxin pair type II binding
BUN12_RS03680	COG3852	Histidine kinase
BUN12_RS03685	COG2105	PFAM AIG2 family protein
BUN12_RS03685	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BUN12_RS03690	COG0569	domain protein
BUN12_RS03700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUN12_RS03715	COG0561	phosphatase activity
BUN12_RS03720	COG0242	peptide deformylase activity
BUN12_RS03730	COG0497	DNA recombination
BUN12_RS03735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_RS03740	COG0022	dehydrogenase e1 component
BUN12_RS03745	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_RS03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_RS03755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS03770	COG1982	Orn Lys Arg decarboxylase major
BUN12_RS03795	COG0483	inositol monophosphate 1-phosphatase activity
BUN12_RS03805	COG3227	Zinc metalloprotease (Elastase)
BUN12_RS03830	COG1217	gtp-binding protein TYPA
BUN12_RS03840	COG4896	Protein conserved in bacteria
BUN12_RS03850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BUN12_RS03855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUN12_RS03860	COG2066	Belongs to the glutaminase family
BUN12_RS03870	COG0772	Belongs to the SEDS family
BUN12_RS03875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUN12_RS03890	COG2010	Cytochrome c
BUN12_RS03890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BUN12_RS03895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUN12_RS03900	COG1845	cytochrome c oxidase, subunit III
BUN12_RS03905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BUN12_RS03910	COG3336	cytochrome c oxidase
BUN12_RS03920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BUN12_RS03925	COG2340	Cysteine-rich secretory protein family
BUN12_RS03940	COG3679	Belongs to the UPF0342 family
BUN12_RS03950	COG0742	ribosomal rna small subunit methyltransferase
BUN12_RS03960	COG3314	Sporulation integral membrane protein YlbJ
BUN12_RS03965	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN12_RS03970	COG3480	Lon protease (S16) C-terminal proteolytic domain
BUN12_RS03980	COG1399	metal-binding, possibly nucleic acid-binding protein
BUN12_RS04000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUN12_RS04020	COG4839	cell division protein FtsL
BUN12_RS04025	COG0768	penicillin binding
BUN12_RS04030	COG0768	penicillin binding
BUN12_RS04050	COG0772	Belongs to the SEDS family
BUN12_RS04065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BUN12_RS04070	COG0849	cell division
BUN12_RS04075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUN12_RS04080	COG1404	Belongs to the peptidase S8 family
BUN12_RS04080	COG4412	M6 family metalloprotease domain protein
BUN12_RS04090	COG1191	sigma factor activity
BUN12_RS04095	COG1191	sigma factor activity
BUN12_RS04100	COG1119	ATPase activity
BUN12_RS04105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_RS04110	COG1873	PFAM PRC-barrel domain
BUN12_RS04115	COG1496	oxidoreductase activity
BUN12_RS04120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUN12_RS04130	COG0762	integral membrane protein
BUN12_RS04135	COG2302	S4 RNA-binding domain
BUN12_RS04140	COG3599	regulation of cell shape
BUN12_RS04150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BUN12_RS04155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_RS04165	COG0564	pseudouridine synthase activity
BUN12_RS04175	COG2233	PERMEase
BUN12_RS04185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUN12_RS04190	COG0505	Belongs to the CarA family
BUN12_RS04195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN12_RS04210	COG0284	orotidine-5'-phosphate decarboxylase activity
BUN12_RS04215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BUN12_RS04225	COG0306	phosphate transporter
BUN12_RS04240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BUN12_RS04245	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BUN12_RS04250	COG1648	precorrin-2 dehydrogenase activity
BUN12_RS04260	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BUN12_RS04265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUN12_RS04270	COG1561	YicC-like family, N-terminal region
BUN12_RS04280	COG0194	GDP metabolic process
BUN12_RS04290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUN12_RS04295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUN12_RS04300	COG0242	peptide deformylase activity
BUN12_RS04310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUN12_RS04310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUN12_RS04320	COG0631	protein serine/threonine phosphatase activity
BUN12_RS04325	COG0515	serine threonine protein kinase
BUN12_RS04325	COG2815	serine threonine protein kinase
BUN12_RS04335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BUN12_RS04340	COG1564	THIamine pyrophosphokinase
BUN12_RS04355	COG1302	Protein conserved in bacteria
BUN12_RS04360	COG1461	Dihydroxyacetone kinase
BUN12_RS04365	COG1760	l-serine dehydratase
BUN12_RS04370	COG1760	l-serine dehydratase
BUN12_RS04375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUN12_RS04390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUN12_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS04410	COG1196	nuclear chromosome segregation
BUN12_RS04415	COG0552	protein localization to endoplasmic reticulum
BUN12_RS04425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUN12_RS04435	COG1837	Belongs to the UPF0109 family
BUN12_RS04460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUN12_RS04475	COG2257	FlhB HrpN YscU SpaS Family
BUN12_RS04485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BUN12_RS04490	COG0758	DNA mediated transformation
BUN12_RS04495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUN12_RS04505	COG4974	Belongs to the 'phage' integrase family
BUN12_RS04525	COG1815	bacterial-type flagellum-dependent cell motility
BUN12_RS04530	COG1558	bacterial-type flagellum-dependent cell motility
BUN12_RS04535	COG1677	Flagellar hook-basal body complex protein FliE
BUN12_RS04540	COG1766	The M ring may be actively involved in energy transduction
BUN12_RS04545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_RS04550	COG1317	bacterial-type flagellum organization
BUN12_RS04555	COG1157	protein secretion by the type III secretion system
BUN12_RS04560	COG2882	bacterial-type flagellum organization
BUN12_RS04565	COG3334	PFAM MgtE intracellular
BUN12_RS04570	COG3144	bacterial-type flagellum assembly
BUN12_RS04575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BUN12_RS04580	COG4786	Flagellar basal body rod
BUN12_RS04585	COG1582	Flagellar protein (FlbD)
BUN12_RS04590	COG1580	Controls the rotational direction of flagella during chemotaxis
BUN12_RS04595	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_RS04600	COG1776	CheC inhibitor of MCP methylation
BUN12_RS04600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUN12_RS04605	COG2201	protein-glutamate methylesterase activity
BUN12_RS04610	COG3190	flagellar
BUN12_RS04615	COG1338	Plays a role in the flagellum-specific transport system
BUN12_RS04620	COG1987	bacterial-type flagellum assembly
BUN12_RS04625	COG1684	flagellar biosynthetic protein fliR
BUN12_RS04630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUN12_RS04635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUN12_RS04640	COG1419	protein localization to endoplasmic reticulum
BUN12_RS04645	COG0455	bacterial-type flagellum organization
BUN12_RS04655	COG2198	Histidine kinase
BUN12_RS04655	COG0643	Histidine kinase
BUN12_RS04660	COG0835	chemotaxis
BUN12_RS04665	COG1776	CheC inhibitor of MCP methylation
BUN12_RS04675	COG1191	sigma factor activity
BUN12_RS04705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BUN12_RS04710	COG4589	Belongs to the CDS family
BUN12_RS04720	COG0750	zinc metalloprotease
BUN12_RS04730	COG2176	DNA-directed DNA polymerase activity
BUN12_RS04740	COG0195	Participates in both transcription termination and antitermination
BUN12_RS04745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BUN12_RS04750	COG1358	cellular component organization or biogenesis
BUN12_RS04760	COG1550	Protein conserved in bacteria
BUN12_RS04775	COG0196	riboflavin kinase activity
BUN12_RS04790	COG0726	polysaccharide deacetylase
BUN12_RS04795	COG0612	Peptidase, M16
BUN12_RS04800	COG1873	PFAM PRC-barrel domain
BUN12_RS04805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN12_RS04810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUN12_RS04815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUN12_RS04820	COG0527	aspartate kinase activity
BUN12_RS04830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUN12_RS04835	COG0740	serine-type endopeptidase activity
BUN12_RS04845	COG4980	gas vesicle protein
BUN12_RS04845	COG1674	ftsk spoiiie
BUN12_RS04850	COG2188	Transcriptional regulator
BUN12_RS04855	COG2814	Major facilitator Superfamily
BUN12_RS04860	COG1846	Transcriptional regulator
BUN12_RS04865	COG1033	growth of symbiont in host cell
BUN12_RS04865	COG2409	Drug exporters of the RND superfamily
BUN12_RS04870	COG0612	Peptidase, M16
BUN12_RS04875	COG0612	Peptidase, M16
BUN12_RS04880	COG0300	oxidoreductase activity
BUN12_RS04895	COG1426	Protein conserved in bacteria
BUN12_RS04900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BUN12_RS04915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_RS04925	COG1692	metallophosphoesterase
BUN12_RS04930	COG2359	stage V sporulation protein S
BUN12_RS04950	COG4550	Control of competence regulator ComK, YlbF/YmcA
BUN12_RS04990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_RS04995	COG3425	synthase
BUN12_RS05000	COG1024	Enoyl-CoA hydratase
BUN12_RS05005	COG1024	Enoyl-CoA hydratase
BUN12_RS05010	COG0300	oxidoreductase activity
BUN12_RS05010	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_RS05010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS05010	COG3321	synthase
BUN12_RS05015	COG4221	oxidoreductase activity
BUN12_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_RS05015	COG3321	synthase
BUN12_RS05015	COG0300	oxidoreductase activity
BUN12_RS05020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_RS05020	COG3321	synthase
BUN12_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS05020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_RS05020	COG3321	synthase
BUN12_RS05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_RS05020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS05025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05025	COG3321	synthase
BUN12_RS05025	COG4221	oxidoreductase activity
BUN12_RS05030	COG3321	synthase
BUN12_RS05030	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BUN12_RS05030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BUN12_RS05030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN12_RS05035	COG2124	cytochrome p450
BUN12_RS05040	COG3209	COG3209 Rhs family protein
BUN12_RS05045	COG3619	membrane
BUN12_RS05055	COG1404	Belongs to the peptidase S8 family
BUN12_RS05065	COG4195	phage-related replication protein
BUN12_RS05070	COG1764	response to oxidative stress
BUN12_RS05080	COG2076	Multidrug Resistance protein
BUN12_RS05120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_RS05125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN12_RS05130	COG4112	unkown
BUN12_RS05140	COG0464	growth
BUN12_RS05145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUN12_RS05150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BUN12_RS05155	COG0789	Transcriptional regulator
BUN12_RS05160	COG0174	glutamine synthetase
BUN12_RS05165	COG0582	viral genome integration into host DNA
BUN12_RS05175	COG1525	nuclease
BUN12_RS05180	COG4282	regulation of fungal-type cell wall biogenesis
BUN12_RS05190	COG5444	nuclease activity
BUN12_RS05220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_RS05230	COG2226	methyltransferase
BUN12_RS05260	COG1063	alcohol dehydrogenase
BUN12_RS05270	COG0457	Tetratricopeptide repeat
BUN12_RS05315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS05330	COG2323	membrane
BUN12_RS05340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS05345	COG2323	membrane
BUN12_RS05360	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BUN12_RS05365	COG0300	oxidoreductase activity
BUN12_RS05380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUN12_RS05385	COG0583	DNA-binding transcription factor activity
BUN12_RS05390	COG0067	glutamate synthase
BUN12_RS05390	COG0069	glutamate synthase activity
BUN12_RS05390	COG0070	glutamate synthase
BUN12_RS05395	COG0493	'glutamate synthase
BUN12_RS05400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BUN12_RS05405	COG0640	Transcriptional regulator
BUN12_RS05410	COG2814	Major facilitator Superfamily
BUN12_RS05415	COG0405	Gamma-glutamyltransferase
BUN12_RS05420	COG0166	Belongs to the GPI family
BUN12_RS05425	COG0582	viral genome integration into host DNA
BUN12_RS05440	COG0534	Mate efflux family protein
BUN12_RS05445	COG2017	converts alpha-aldose to the beta-anomer
BUN12_RS05450	COG2027	D-alanyl-D-alanine carboxypeptidase
BUN12_RS05460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS05465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BUN12_RS05475	COG1649	PFAM Uncharacterised BCR, COG1649
BUN12_RS05480	COG1960	acyl-CoA dehydrogenase activity
BUN12_RS05490	COG0439	Biotin carboxylase
BUN12_RS05495	COG0511	ligase activity, forming carbon-carbon bonds
BUN12_RS05500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUN12_RS05505	COG1024	Enoyl-CoA hydratase
BUN12_RS05510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN12_RS05515	COG0586	Pfam SNARE associated Golgi protein
BUN12_RS05520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUN12_RS05525	COG2246	polysaccharide biosynthetic process
BUN12_RS05535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_RS05555	COG2124	cytochrome p450
BUN12_RS05560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUN12_RS05565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUN12_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS05600	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_RS05610	COG0745	RESPONSE REGULATOR receiver
BUN12_RS05615	COG2205	protein histidine kinase activity
BUN12_RS05645	COG1115	amino acid carrier protein
BUN12_RS05655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUN12_RS05660	COG0187	DNA topoisomerase II activity
BUN12_RS05665	COG1832	CoA-binding protein
BUN12_RS05675	COG4841	protein insertion into membrane
BUN12_RS05685	COG0824	Thioesterase
BUN12_RS05705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS05710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BUN12_RS05725	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_RS05735	COG4846	Membrane protein involved in cytochrome C biogenesis
BUN12_RS05740	COG2201	protein-glutamate methylesterase activity
BUN12_RS05745	COG0785	Cytochrome C biogenesis protein
BUN12_RS05765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUN12_RS05775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUN12_RS05805	COG4195	phage-related replication protein
BUN12_RS05815	COG0756	dUTP diphosphatase activity
BUN12_RS05820	COG2314	TM2 domain
BUN12_RS05825	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS05840	COG3397	chitin binding
BUN12_RS05875	COG0456	acetyltransferase
BUN12_RS05895	COG1064	alcohol dehydrogenase
BUN12_RS05900	COG2318	DinB family
BUN12_RS05910	COG2323	membrane
BUN12_RS05915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS05925	COG2323	membrane
BUN12_RS05940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS05980	COG2814	Major facilitator Superfamily
BUN12_RS05985	COG1070	Carbohydrate kinase
BUN12_RS05995	COG0243	molybdopterin cofactor binding
BUN12_RS06025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_RS06030	COG2207	Transcriptional regulator
BUN12_RS06030	COG0662	Cupin 2, conserved barrel domain protein
BUN12_RS06035	COG1309	transcriptional regulator
BUN12_RS06040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS06050	COG0640	Transcriptional regulator
BUN12_RS06055	COG0741	lytic transglycosylase activity
BUN12_RS06060	COG2322	membrane
BUN12_RS06075	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUN12_RS06085	COG3584	3D domain protein
BUN12_RS06085	COG1388	LysM domain
BUN12_RS06090	COG0514	ATP-dependent DNA helicase (RecQ)
BUN12_RS06100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUN12_RS06105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_RS06120	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_RS06150	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS06155	COG1657	PFAM Prenyltransferase squalene oxidase
BUN12_RS06160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUN12_RS06165	COG0733	neurotransmitter:sodium symporter activity
BUN12_RS06170	COG0385	Bile acid
BUN12_RS06175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS06180	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_RS06190	COG4548	von Willebrand factor, type A
BUN12_RS06195	COG0714	Associated with various cellular activities
BUN12_RS06200	COG2032	superoxide dismutase activity
BUN12_RS06205	COG0791	NLP P60 protein
BUN12_RS06205	COG1388	LysM domain
BUN12_RS06210	COG1819	glycosyl
BUN12_RS06215	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUN12_RS06220	COG0534	Mate efflux family protein
BUN12_RS06225	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS06230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_RS06235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_RS06245	COG2962	Rard protein
BUN12_RS06260	COG1942	4-Oxalocrotonate Tautomerase
BUN12_RS06270	COG1733	regulation of RNA biosynthetic process
BUN12_RS06275	COG0778	Nitroreductase
BUN12_RS06285	COG0346	lactoylglutathione lyase activity
BUN12_RS06295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_RS06305	COG2723	6-phospho-beta-galactosidase activity
BUN12_RS06310	COG2188	Transcriptional regulator
BUN12_RS06315	COG0793	Belongs to the peptidase S41A family
BUN12_RS06315	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS06330	COG1876	peptidase activity
BUN12_RS06350	COG0671	phosphoesterase, PA-phosphatase related
BUN12_RS06365	COG0346	lactoylglutathione lyase activity
BUN12_RS06380	COG1509	lysine 2,3-aminomutase activity
BUN12_RS06385	COG0456	acetyltransferase
BUN12_RS06390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_RS06395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUN12_RS06400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUN12_RS06405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUN12_RS06415	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BUN12_RS06425	COG0456	acetyltransferase
BUN12_RS06430	COG0463	Glycosyl transferase, family 2
BUN12_RS06445	COG4641	Protein conserved in bacteria
BUN12_RS06455	COG1086	Polysaccharide biosynthesis protein
BUN12_RS06480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUN12_RS06485	COG1086	Polysaccharide biosynthesis protein
BUN12_RS06500	COG1846	Transcriptional regulator
BUN12_RS06505	COG4698	Protein conserved in bacteria
BUN12_RS06510	COG2755	lipolytic protein G-D-S-L family
BUN12_RS06515	COG1999	signal sequence binding
BUN12_RS06525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BUN12_RS06530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BUN12_RS06535	COG1272	protein, Hemolysin III
BUN12_RS06540	COG0204	Acyl-transferase
BUN12_RS06545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUN12_RS06550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BUN12_RS06560	COG2521	methyltransferase
BUN12_RS06560	COG2136	Putative SAM-dependent methyltransferase
BUN12_RS06575	COG1413	lyase activity
BUN12_RS06580	COG1418	mRNA catabolic process
BUN12_RS06585	COG0386	Belongs to the glutathione peroxidase family
BUN12_RS06595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUN12_RS06605	COG1278	Cold shock
BUN12_RS06625	COG0328	RNA-DNA hybrid ribonuclease activity
BUN12_RS06630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BUN12_RS06635	COG0328	RNA-DNA hybrid ribonuclease activity
BUN12_RS06645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS06660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUN12_RS06670	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUN12_RS06675	COG3424	synthase
BUN12_RS06700	COG2233	PERMEase
BUN12_RS06710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUN12_RS06715	COG1199	ATP-dependent helicase activity
BUN12_RS06735	COG0116	Belongs to the methyltransferase superfamily
BUN12_RS06765	COG3359	exonuclease
BUN12_RS06770	COG1111	helicase
BUN12_RS06770	COG1205	dead DEAH box helicase
BUN12_RS06775	COG2190	(PTS) system
BUN12_RS06780	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_RS06820	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUN12_RS06820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_RS06830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BUN12_RS06835	COG3935	DnaD domain protein
BUN12_RS06845	COG0436	Aminotransferase
BUN12_RS06850	COG5353	protein conserved in bacteria
BUN12_RS06860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BUN12_RS06860	COG1199	ATP-dependent helicase activity
BUN12_RS06890	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS06895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_RS06910	COG1694	Mazg nucleotide pyrophosphohydrolase
BUN12_RS06915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS06920	COG2140	Oxalate decarboxylase
BUN12_RS06930	COG4347	Protein of unknown function (DUF1405)
BUN12_RS06935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUN12_RS06935	COG2010	Cytochrome c
BUN12_RS06940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUN12_RS06945	COG0723	plastoquinol--plastocyanin reductase activity
BUN12_RS06960	COG0457	Tetratricopeptide repeat
BUN12_RS06970	COG0287	Prephenate dehydrogenase
BUN12_RS07005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN12_RS07010	COG4401	Chorismate mutase type I
BUN12_RS07025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUN12_RS07030	COG0105	UTP biosynthetic process
BUN12_RS07035	COG0142	geranyltranstransferase activity
BUN12_RS07045	COG0142	geranyltranstransferase activity
BUN12_RS07060	COG0776	regulation of translation
BUN12_RS07065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUN12_RS07105	COG0539	negative regulation of cytoplasmic translation
BUN12_RS07115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BUN12_RS07120	COG2959	enzyme of heme biosynthesis
BUN12_RS07125	COG3773	Cell wall hydrolase
BUN12_RS07125	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS07130	COG2339	peptidase activity
BUN12_RS07135	COG0492	ferredoxin-NADP+ reductase activity
BUN12_RS07140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_RS07145	COG4862	establishment of competence for transformation
BUN12_RS07150	COG1408	metallophosphoesterase
BUN12_RS07160	COG1388	LysM domain
BUN12_RS07165	COG1266	CAAX protease self-immunity
BUN12_RS07170	COG0514	ATP-dependent DNA helicase (RecQ)
BUN12_RS07175	COG4955	Helix-turn-helix domain
BUN12_RS07180	COG1141	Ferredoxin
BUN12_RS07185	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BUN12_RS07190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN12_RS07200	COG1595	DNA-templated transcription, initiation
BUN12_RS07205	COG5002	protein histidine kinase activity
BUN12_RS07210	COG0745	RESPONSE REGULATOR receiver
BUN12_RS07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN12_RS07220	COG1333	cytochrome c biogenesis protein
BUN12_RS07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS07230	COG1187	pseudouridine synthase activity
BUN12_RS07235	COG0700	Nucleoside recognition
BUN12_RS07240	COG2715	membrane protein required for spore maturation
BUN12_RS07245	COG1686	Belongs to the peptidase S11 family
BUN12_RS07270	COG1547	Domain of unknown function (DUF309)
BUN12_RS07280	COG0456	acetyltransferase
BUN12_RS07285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BUN12_RS07290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN12_RS07290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN12_RS07295	COG0307	riboflavin synthase, alpha
BUN12_RS07300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN12_RS07300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN12_RS07310	COG0681	Belongs to the peptidase S26 family
BUN12_RS07320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BUN12_RS07325	COG4086	secreted protein
BUN12_RS07330	COG0019	diaminopimelate decarboxylase activity
BUN12_RS07335	COG0697	spore germination
BUN12_RS07350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS07370	COG1191	sigma factor activity
BUN12_RS07380	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS07385	COG1686	Belongs to the peptidase S11 family
BUN12_RS07390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BUN12_RS07395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BUN12_RS07400	COG4974	Belongs to the 'phage' integrase family
BUN12_RS07410	COG0735	belongs to the Fur family
BUN12_RS07415	COG1300	Membrane
BUN12_RS07430	COG0281	malic enzyme
BUN12_RS07435	COG1757	Na H antiporter
BUN12_RS07440	COG1027	Aspartate ammonia-lyase
BUN12_RS07445	COG0252	asparaginase activity
BUN12_RS07450	COG1396	sequence-specific DNA binding
BUN12_RS07455	COG1379	DNA repair
BUN12_RS07460	COG0494	nUDIX hydrolase
BUN12_RS07470	COG0667	Aldo Keto reductase
BUN12_RS07490	COG4918	Iron-sulphur cluster biosynthesis
BUN12_RS07495	COG0456	acetyltransferase
BUN12_RS07495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUN12_RS07500	COG0456	acetyltransferase
BUN12_RS07505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUN12_RS07520	COG0628	permease
BUN12_RS07535	COG3048	D-serine ammonia-lyase activity
BUN12_RS07540	COG0300	oxidoreductase activity
BUN12_RS07545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS07550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUN12_RS07575	COG0596	Alpha beta hydrolase
BUN12_RS07590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUN12_RS07595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUN12_RS07610	COG0706	membrane insertase activity
BUN12_RS07615	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUN12_RS07620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN12_RS07625	COG0346	lactoylglutathione lyase activity
BUN12_RS07630	COG1376	ErfK ybiS ycfS ynhG family protein
BUN12_RS07635	COG4129	membrane
BUN12_RS07640	COG1126	abc transporter atp-binding protein
BUN12_RS07645	COG0765	amino acid transport
BUN12_RS07650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS07660	COG1597	lipid kinase activity
BUN12_RS07665	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_RS07670	COG0022	dehydrogenase e1 component
BUN12_RS07675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_RS07680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_RS07685	COG3426	butyrate kinase activity
BUN12_RS07690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_RS07695	COG0280	phosphate acetyltransferase
BUN12_RS07700	COG3290	protein histidine kinase activity
BUN12_RS07700	COG3829	transcription factor binding
BUN12_RS07710	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BUN12_RS07715	COG2079	MmgE PrpD family protein
BUN12_RS07720	COG0372	Belongs to the citrate synthase family
BUN12_RS07725	COG1960	acyl-CoA dehydrogenase activity
BUN12_RS07735	COG0183	Belongs to the thiolase family
BUN12_RS07740	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_RS07745	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS07765	COG1902	pentaerythritol trinitrate reductase activity
BUN12_RS07780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUN12_RS07785	COG0745	RESPONSE REGULATOR receiver
BUN12_RS07790	COG0750	zinc metalloprotease
BUN12_RS07795	COG0497	DNA recombination
BUN12_RS07805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BUN12_RS07815	COG0142	geranyltranstransferase activity
BUN12_RS07825	COG1570	exodeoxyribonuclease VII activity
BUN12_RS07840	COG1302	Protein conserved in bacteria
BUN12_RS07845	COG0439	Biotin carboxylase
BUN12_RS07850	COG0511	ligase activity, forming carbon-carbon bonds
BUN12_RS07890	COG3854	ATPases associated with a variety of cellular activities
BUN12_RS07905	COG0006	proline dipeptidase activity
BUN12_RS07915	COG3872	metal-dependent enzyme
BUN12_RS07925	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN12_RS07940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUN12_RS07960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUN12_RS07975	COG1396	sequence-specific DNA binding
BUN12_RS07985	COG0681	Belongs to the peptidase S26 family
BUN12_RS08010	COG4940	Competence protein ComGF
BUN12_RS08020	COG4970	Tfp pilus assembly protein FimT
BUN12_RS08025	COG4537	Required for transformation and DNA binding
BUN12_RS08030	COG1459	type II secretion system
BUN12_RS08035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BUN12_RS08040	COG0598	Magnesium transport protein CorA
BUN12_RS08045	COG1253	flavin adenine dinucleotide binding
BUN12_RS08050	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS08060	COG1393	Belongs to the ArsC family
BUN12_RS08070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS08080	COG0011	TIGRFAM Protein of
BUN12_RS08090	COG2866	Carboxypeptidase
BUN12_RS08095	COG1940	carbohydrate kinase activity
BUN12_RS08100	COG4483	Protein conserved in bacteria
BUN12_RS08105	COG1757	Na H antiporter
BUN12_RS08115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUN12_RS08130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUN12_RS08135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN12_RS08140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN12_RS08145	COG0581	inorganic phosphate transmembrane transporter activity
BUN12_RS08150	COG0573	inorganic phosphate transmembrane transporter activity
BUN12_RS08155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUN12_RS08160	COG0768	penicillin binding
BUN12_RS08165	COG0477	Major facilitator Superfamily
BUN12_RS08170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUN12_RS08175	COG2839	Protein conserved in bacteria
BUN12_RS08180	COG5521	maltodextrose utilization protein MalA
BUN12_RS08185	COG1388	LysM domain
BUN12_RS08195	COG4709	membrane
BUN12_RS08200	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BUN12_RS08205	COG0735	belongs to the Fur family
BUN12_RS08210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS08225	COG0513	Belongs to the DEAD box helicase family
BUN12_RS08240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUN12_RS08245	COG2384	SAM-dependent methyltransferase
BUN12_RS08250	COG2010	Cytochrome c
BUN12_RS08255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUN12_RS08260	COG0358	DNA primase activity
BUN12_RS08275	COG0517	IMP dehydrogenase activity
BUN12_RS08280	COG0751	glycine-tRNA ligase activity
BUN12_RS08300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BUN12_RS08305	COG0295	cytidine deaminase activity
BUN12_RS08310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BUN12_RS08320	COG1480	7TM receptor with intracellular HD hydrolase
BUN12_RS08325	COG1702	phosphate starvation-inducible protein PhoH
BUN12_RS08330	COG0561	phosphatase activity
BUN12_RS08345	COG4864	UPF0365 protein
BUN12_RS08350	COG1030	water channel activity
BUN12_RS08355	COG1610	YqeY-like protein
BUN12_RS08365	COG1283	sodium-dependent phosphate transmembrane transporter activity
BUN12_RS08370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUN12_RS08375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BUN12_RS08405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN12_RS08420	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS08435	COG1466	dna polymerase III delta subunit
BUN12_RS08450	COG2333	competence protein COMEC
BUN12_RS08450	COG0658	competence protein
BUN12_RS08455	COG2131	deaminase
BUN12_RS08460	COG1555	photosystem II stabilization
BUN12_RS08460	COG1596	polysaccharide export
BUN12_RS08465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUN12_RS08470	COG2226	methyltransferase
BUN12_RS08475	COG0799	negative regulation of ribosome biogenesis
BUN12_RS08480	COG1713	HD superfamily hydrolase involved in NAD metabolism
BUN12_RS08490	COG1534	Rna-binding protein
BUN12_RS08495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUN12_RS08500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUN12_RS08505	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BUN12_RS08515	COG2755	lipolytic protein G-D-S-L family
BUN12_RS08525	COG0398	Pfam SNARE associated Golgi protein
BUN12_RS08585	COG0512	Glutamine amidotransferase of anthranilate synthase
BUN12_RS08610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BUN12_RS08625	COG2378	regulation of single-species biofilm formation
BUN12_RS08630	COG0693	protein deglycase activity
BUN12_RS08650	COG0457	Tetratricopeptide repeat
BUN12_RS08675	COG1794	racemase activity, acting on amino acids and derivatives
BUN12_RS08690	COG1733	regulation of RNA biosynthetic process
BUN12_RS08695	COG0656	L-ascorbic acid biosynthetic process
BUN12_RS08730	COG0563	adenylate kinase activity
BUN12_RS08740	COG2814	Major facilitator Superfamily
BUN12_RS08750	COG0456	acetyltransferase
BUN12_RS08755	COG2318	DinB family
BUN12_RS08765	COG0561	phosphatase activity
BUN12_RS08780	COG1482	cell wall glycoprotein biosynthetic process
BUN12_RS08785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_RS08785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUN12_RS08785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS08790	COG3711	transcriptional antiterminator
BUN12_RS08790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS08800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUN12_RS08805	COG0583	DNA-binding transcription factor activity
BUN12_RS08810	COG2814	Major facilitator Superfamily
BUN12_RS08815	COG2124	cytochrome p450
BUN12_RS08815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_RS08820	COG1309	transcriptional regulator
BUN12_RS08825	COG2226	methyltransferase
BUN12_RS08840	COG2116	formate transmembrane transporter activity
BUN12_RS08845	COG5609	conserved protein (DUF2294)
BUN12_RS08850	COG3383	formate dehydrogenase (NAD+) activity
BUN12_RS08855	COG2427	Protein of unknown function (DUF1641)
BUN12_RS08865	COG0626	cystathionine gamma-synthase activity
BUN12_RS08870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_RS08895	COG0768	penicillin binding
BUN12_RS08910	COG0826	peptidase U32
BUN12_RS08915	COG0826	peptidase U32
BUN12_RS08920	COG4122	O-methyltransferase activity
BUN12_RS08925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUN12_RS08950	COG0628	permease
BUN12_RS08955	COG1126	abc transporter atp-binding protein
BUN12_RS08960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS08965	COG0765	amino acid transport
BUN12_RS08970	COG0765	amino acid transport
BUN12_RS08985	COG3881	PFAM PRC-barrel domain
BUN12_RS08990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUN12_RS08995	COG0457	Tetratricopeptide repeat
BUN12_RS09005	COG1104	cysteine desulfurase activity
BUN12_RS09010	COG1959	2 iron, 2 sulfur cluster binding
BUN12_RS09015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUN12_RS09020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BUN12_RS09045	COG3103	Sh3 type 3 domain protein
BUN12_RS09045	COG4991	sh3 domain protein
BUN12_RS09045	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS09050	COG1490	D-aminoacyl-tRNA deacylase activity
BUN12_RS09055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUN12_RS09065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUN12_RS09065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUN12_RS09070	COG5416	Lipopolysaccharide assembly protein A domain
BUN12_RS09075	COG0490	domain, Protein
BUN12_RS09080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUN12_RS09080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUN12_RS09090	COG2244	polysaccharide biosynthetic process
BUN12_RS09095	COG2323	membrane
BUN12_RS09105	COG1862	Preprotein translocase
BUN12_RS09145	COG1388	LysM domain
BUN12_RS09155	COG0157	Belongs to the NadC ModD family
BUN12_RS09160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BUN12_RS09165	COG1104	cysteine desulfurase activity
BUN12_RS09170	COG1827	regulation of RNA biosynthetic process
BUN12_RS09175	COG0077	Prephenate dehydratase
BUN12_RS09190	COG3290	protein histidine kinase activity
BUN12_RS09195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BUN12_RS09200	COG2868	ribosomal protein
BUN12_RS09210	COG1994	Peptidase M50
BUN12_RS09215	COG0739	heme binding
BUN12_RS09220	COG2894	cell division
BUN12_RS09225	COG0850	regulation of cytokinetic process
BUN12_RS09230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BUN12_RS09240	COG1077	Cell shape determining protein MreB Mrl
BUN12_RS09260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BUN12_RS09265	COG0285	dihydrofolate synthase activity
BUN12_RS09270	COG0525	valine-tRNA ligase activity
BUN12_RS09280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_RS09285	COG1388	LysM domain
BUN12_RS09295	COG0113	porphobilinogen synthase activity
BUN12_RS09300	COG1587	Uroporphyrinogen-III synthase
BUN12_RS09310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN12_RS09330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BUN12_RS09335	COG0470	DNA polymerase III
BUN12_RS09335	COG1067	ATP-dependent peptidase activity
BUN12_RS09350	COG0457	Tetratricopeptide repeat
BUN12_RS09350	COG1477	protein flavinylation
BUN12_RS09365	COG0473	3-isopropylmalate dehydrogenase activity
BUN12_RS09380	COG0440	acetolactate synthase activity
BUN12_RS09385	COG0028	Belongs to the TPP enzyme family
BUN12_RS09410	COG0622	Phosphoesterase
BUN12_RS09415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BUN12_RS09425	COG5401	PFAM Sporulation and spore germination
BUN12_RS09435	COG1846	Transcriptional regulator
BUN12_RS09440	COG2197	response regulator
BUN12_RS09445	COG0824	Thioesterase
BUN12_RS09450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BUN12_RS09455	COG1053	succinate dehydrogenase
BUN12_RS09460	COG2009	succinate dehydrogenase
BUN12_RS09465	COG1719	4-vinyl reductase, 4VR
BUN12_RS09470	COG0527	aspartate kinase activity
BUN12_RS09480	COG3118	belongs to the thioredoxin family
BUN12_RS09485	COG3534	alpha-L-arabinofuranosidase
BUN12_RS09490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BUN12_RS09495	COG2086	electron transfer activity
BUN12_RS09500	COG1024	Enoyl-CoA hydratase
BUN12_RS09505	COG1309	transcriptional regulator
BUN12_RS09510	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_RS09520	COG3766	membrane
BUN12_RS09530	COG1796	DNA polymerase
BUN12_RS09530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUN12_RS09535	COG1286	toxin biosynthetic process
BUN12_RS09550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_RS09550	COG0072	phenylalanine-tRNA ligase activity
BUN12_RS09555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BUN12_RS09560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUN12_RS09570	COG3835	regulator
BUN12_RS09575	COG0277	FAD linked oxidase domain protein
BUN12_RS09580	COG0247	lactate metabolic process
BUN12_RS09585	COG1966	Carbon starvation protein
BUN12_RS09590	COG3534	alpha-L-arabinofuranosidase
BUN12_RS09595	COG0395	ABC-type sugar transport system, permease component
BUN12_RS09600	COG1175	transmembrane transport
BUN12_RS09605	COG1653	transport
BUN12_RS09615	COG0647	UMP catabolic process
BUN12_RS09620	COG0235	Class ii aldolase
BUN12_RS09625	COG1069	ribulokinase activity
BUN12_RS09630	COG2160	L-arabinose isomerase activity
BUN12_RS09635	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_RS09640	COG1363	Peptidase, m42
BUN12_RS09650	COG3326	Membrane
BUN12_RS09655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BUN12_RS09665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BUN12_RS09670	COG1346	cytolysis
BUN12_RS09675	COG1380	Effector of murein hydrolase LrgA
BUN12_RS09680	COG3279	Response regulator of the LytR AlgR family
BUN12_RS09685	COG3275	phosphorelay sensor kinase activity
BUN12_RS09690	COG1011	Hydrolase
BUN12_RS09705	COG0398	Pfam SNARE associated Golgi protein
BUN12_RS09710	COG1484	DNA-dependent DNA replication
BUN12_RS09715	COG3611	Membrane attachment protein
BUN12_RS09730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUN12_RS09735	COG1733	regulation of RNA biosynthetic process
BUN12_RS09740	COG2814	Major facilitator Superfamily
BUN12_RS09745	COG0656	L-ascorbic acid biosynthetic process
BUN12_RS09750	COG0237	dephospho-CoA kinase activity
BUN12_RS09755	COG1971	Probably functions as a manganese efflux pump
BUN12_RS09760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BUN12_RS09765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS09765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS09770	COG5002	protein histidine kinase activity
BUN12_RS09775	COG0745	RESPONSE REGULATOR receiver
BUN12_RS09785	COG0538	isocitrate dehydrogenase activity
BUN12_RS09790	COG0372	Belongs to the citrate synthase family
BUN12_RS09800	COG0628	permease
BUN12_RS09805	COG3030	protein affecting phage T7 exclusion by the F plasmid
BUN12_RS09810	COG0469	pyruvate kinase activity
BUN12_RS09830	COG0281	malic enzyme
BUN12_RS09835	COG0587	DNA-directed DNA polymerase activity
BUN12_RS09855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUN12_RS09865	COG4109	DRTGG domain
BUN12_RS09875	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS09890	COG0521	Mo-molybdopterin cofactor biosynthetic process
BUN12_RS09900	COG0827	DNA restriction-modification system
BUN12_RS09905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUN12_RS09910	COG3874	Sporulation protein YtfJ
BUN12_RS09920	COG1714	RDD family
BUN12_RS09925	COG0616	signal peptide processing
BUN12_RS09930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUN12_RS09935	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BUN12_RS09940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUN12_RS09955	COG1104	cysteine desulfurase activity
BUN12_RS09960	COG1114	Component of the transport system for branched-chain amino acids
BUN12_RS09970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUN12_RS09975	COG1309	transcriptional regulator
BUN12_RS09980	COG1956	GAF domain-containing protein
BUN12_RS09985	COG2203	Gaf domain
BUN12_RS09985	COG2199	diguanylate cyclase activity
BUN12_RS10000	COG1017	nitric oxide dioxygenase activity
BUN12_RS10000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUN12_RS10025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_RS10030	COG1378	Sugar-specific transcriptional regulator TrmB
BUN12_RS10035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BUN12_RS10050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUN12_RS10055	COG0454	-acetyltransferase
BUN12_RS10060	COG0517	IMP dehydrogenase activity
BUN12_RS10065	COG0123	including yeast histone deacetylase and acetoin utilization protein
BUN12_RS10070	COG1360	Flagellar Motor Protein
BUN12_RS10075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUN12_RS10080	COG1609	Transcriptional regulator
BUN12_RS10085	COG1605	Chorismate mutase
BUN12_RS10085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUN12_RS10090	COG3118	belongs to the thioredoxin family
BUN12_RS10095	COG4980	gas vesicle protein
BUN12_RS10100	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BUN12_RS10110	COG1674	ftsk spoiiie
BUN12_RS10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_RS10125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS10135	COG1363	Peptidase, m42
BUN12_RS10140	COG5584	Small secreted protein
BUN12_RS10150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN12_RS10165	COG0510	thiamine kinase activity
BUN12_RS10170	COG1597	lipid kinase activity
BUN12_RS10180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BUN12_RS10185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_RS10190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_RS10195	COG2252	PERMEase
BUN12_RS10200	COG4473	ABC transporter
BUN12_RS10205	COG1131	(ABC) transporter
BUN12_RS10210	COG1349	DNA-binding transcription factor activity
BUN12_RS10215	COG1187	pseudouridine synthase activity
BUN12_RS10220	COG2244	polysaccharide biosynthetic process
BUN12_RS10225	COG2081	HI0933 family
BUN12_RS10230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BUN12_RS10240	COG1609	Transcriptional regulator
BUN12_RS10245	COG1653	transport
BUN12_RS10250	COG1175	transmembrane transport
BUN12_RS10255	COG0395	ABC-type sugar transport system, permease component
BUN12_RS10260	COG1486	melibiose metabolic process
BUN12_RS10270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUN12_RS10285	COG2202	Pas domain
BUN12_RS10285	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS10290	COG2814	Major facilitator Superfamily
BUN12_RS10300	COG0577	efflux transmembrane transporter activity
BUN12_RS10305	COG1136	(ABC) transporter
BUN12_RS10310	COG2205	protein histidine kinase activity
BUN12_RS10315	COG0745	RESPONSE REGULATOR receiver
BUN12_RS10320	COG0577	efflux transmembrane transporter activity
BUN12_RS10325	COG1136	(ABC) transporter
BUN12_RS10345	COG1131	(ABC) transporter
BUN12_RS10350	COG1725	Transcriptional regulator
BUN12_RS10360	COG1242	4 iron, 4 sulfur cluster binding
BUN12_RS10365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BUN12_RS10380	COG2267	carboxylic ester hydrolase activity
BUN12_RS10385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BUN12_RS10390	COG1113	amino acid transport
BUN12_RS10395	COG0367	asparagine synthase
BUN12_RS10415	COG1506	peptidase
BUN12_RS10420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUN12_RS10425	COG1116	anion transmembrane transporter activity
BUN12_RS10430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUN12_RS10435	COG0494	nUDIX hydrolase
BUN12_RS10440	COG4824	toxin secretion phage lysis holin
BUN12_RS10445	COG0783	Belongs to the Dps family
BUN12_RS10470	COG0288	reversible hydration of carbon dioxide
BUN12_RS10480	COG1271	oxidase subunit
BUN12_RS10485	COG1294	oxidase, subunit
BUN12_RS10495	COG4948	Mandelate Racemase Muconate Lactonizing
BUN12_RS10505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BUN12_RS10510	COG0596	Alpha beta hydrolase
BUN12_RS10520	COG1169	isochorismate synthase
BUN12_RS10525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUN12_RS10530	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BUN12_RS10655	COG3859	Proton-coupled thiamine transporter YuaJ
BUN12_RS10660	COG2268	Band 7 protein
BUN12_RS10665	COG1585	Membrane protein implicated in regulation of membrane protease activity
BUN12_RS10670	COG2318	DinB family
BUN12_RS10680	COG1454	alcohol dehydrogenase
BUN12_RS10685	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS10690	COG1510	regulation of RNA biosynthetic process
BUN12_RS10700	COG0569	domain protein
BUN12_RS10705	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_RS10710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUN12_RS10710	COG1017	nitric oxide dioxygenase activity
BUN12_RS10725	COG0457	Tetratricopeptide repeat
BUN12_RS10785	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS10790	COG4824	toxin secretion phage lysis holin
BUN12_RS10810	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS10825	COG3953	SLT domain
BUN12_RS10825	COG5412	phage tail tape measure protein
BUN12_RS10965	COG0582	viral genome integration into host DNA
BUN12_RS10980	COG0628	permease
BUN12_RS10985	COG0673	inositol 2-dehydrogenase activity
BUN12_RS10990	COG0693	protein deglycase activity
BUN12_RS10995	COG0840	transmembrane signaling receptor activity
BUN12_RS11000	COG0840	transmembrane signaling receptor activity
BUN12_RS11005	COG0840	transmembrane signaling receptor activity
BUN12_RS11010	COG0840	transmembrane signaling receptor activity
BUN12_RS11025	COG2070	2-Nitropropane dioxygenase
BUN12_RS11035	COG0366	Alpha amylase catalytic
BUN12_RS11040	COG1253	flavin adenine dinucleotide binding
BUN12_RS11045	COG2738	Putative neutral zinc metallopeptidase
BUN12_RS11060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUN12_RS11080	COG1979	alcohol dehydrogenase
BUN12_RS11085	COG1979	alcohol dehydrogenase
BUN12_RS11090	COG2155	Conserved Protein
BUN12_RS11095	COG1098	S1 RNA binding domain
BUN12_RS11100	COG0436	Aminotransferase
BUN12_RS11105	COG1522	sequence-specific DNA binding
BUN12_RS11110	COG2267	carboxylic ester hydrolase activity
BUN12_RS11120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUN12_RS11125	COG2205	protein histidine kinase activity
BUN12_RS11135	COG5018	Exonuclease
BUN12_RS11140	COG2814	Major facilitator Superfamily
BUN12_RS11145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_RS11150	COG3011	Protein conserved in bacteria
BUN12_RS11160	COG3290	protein histidine kinase activity
BUN12_RS11165	COG4565	transcriptional regulatory protein
BUN12_RS11170	COG1744	ABC transporter substrate-binding protein PnrA-like
BUN12_RS11175	COG3845	ABC transporter
BUN12_RS11180	COG4603	Belongs to the binding-protein-dependent transport system permease family
BUN12_RS11185	COG1079	Belongs to the binding-protein-dependent transport system permease family
BUN12_RS11195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BUN12_RS11195	COG2111	Na H antiporter
BUN12_RS11200	COG2111	Na H antiporter
BUN12_RS11205	COG1006	Multisubunit Na H antiporter MnhC subunit
BUN12_RS11210	COG0651	ATP synthesis coupled electron transport
BUN12_RS11215	COG1863	multisubunit Na H antiporter MnhE subunit
BUN12_RS11220	COG2212	antiporter activity
BUN12_RS11225	COG1320	monovalent cation:proton antiporter activity
BUN12_RS11230	COG2050	protein possibly involved in aromatic compounds catabolism
BUN12_RS11235	COG2197	response regulator
BUN12_RS11240	COG4585	Histidine kinase
BUN12_RS11250	COG0142	geranyltranstransferase activity
BUN12_RS11270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BUN12_RS11275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUN12_RS11280	COG1335	isochorismatase
BUN12_RS11285	COG5506	Protein of unknown function (DUF1694)
BUN12_RS11300	COG0628	permease
BUN12_RS11310	COG1418	mRNA catabolic process
BUN12_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS11325	COG1511	domain protein
BUN12_RS11330	COG0433	COG0433 Predicted ATPase
BUN12_RS11330	COG1674	ftsk spoiiie
BUN12_RS11335	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUN12_RS11340	COG5417	Belongs to the EsaB family
BUN12_RS11345	COG4842	Belongs to the WXG100 family
BUN12_RS11350	COG2508	Transcriptional regulator
BUN12_RS11350	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUN12_RS11355	COG0686	Belongs to the AlaDH PNT family
BUN12_RS11360	COG5634	Uncharacterized conserved protein (DUF2278)
BUN12_RS11365	COG3251	PFAM MbtH domain protein
BUN12_RS11370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS11375	COG3433	isochorismatase activity
BUN12_RS11375	COG1535	isochorismatase
BUN12_RS11380	COG1021	2,3-dihydroxybenzoate-AMP ligase
BUN12_RS11385	COG1169	isochorismate synthase
BUN12_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS11395	COG2819	hydrolase of the alpha beta superfamily
BUN12_RS11400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUN12_RS11405	COG1268	BioY protein
BUN12_RS11410	COG2056	Na+-H+ antiporter family
BUN12_RS11420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BUN12_RS11425	COG3584	3D domain protein
BUN12_RS11440	COG1252	NADH dehydrogenase
BUN12_RS11470	COG1131	(ABC) transporter
BUN12_RS11495	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUN12_RS11500	COG0316	Belongs to the HesB IscA family
BUN12_RS11510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_RS11520	COG1252	NADH dehydrogenase
BUN12_RS11525	COG4837	Protein of unknown function (DUF1462)
BUN12_RS11530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BUN12_RS11545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUN12_RS11550	COG0460	homoserine dehydrogenase
BUN12_RS11555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_RS11560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUN12_RS11565	COG0647	UMP catabolic process
BUN12_RS11570	COG2445	Protein of unknown function DUF86
BUN12_RS11575	COG4470	Protein conserved in bacteria
BUN12_RS11590	COG0739	heme binding
BUN12_RS11600	COG0737	Belongs to the 5'-nucleotidase family
BUN12_RS11605	COG0730	response to heat
BUN12_RS11610	COG1801	Protein of unknown function DUF72
BUN12_RS11625	COG2508	Transcriptional regulator
BUN12_RS11635	COG3195	allantoin biosynthetic process
BUN12_RS11635	COG3648	Uricase
BUN12_RS11645	COG2814	Major facilitator Superfamily
BUN12_RS11650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BUN12_RS11655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN12_RS11660	COG2356	endonuclease I
BUN12_RS11665	COG3842	ATPase activity
BUN12_RS11670	COG2188	Transcriptional regulator
BUN12_RS11675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_RS11680	COG0395	ABC-type sugar transport system, permease component
BUN12_RS11685	COG1175	transmembrane transport
BUN12_RS11690	COG1653	transport
BUN12_RS11695	COG2222	sugar isomerase
BUN12_RS11700	COG0789	Transcriptional regulator
BUN12_RS11725	COG0322	excinuclease ABC activity
BUN12_RS11730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN12_RS11745	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS11760	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS11760	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS11765	COG4824	toxin secretion phage lysis holin
BUN12_RS11785	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS11790	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN12_RS11800	COG5412	phage tail tape measure protein
BUN12_RS11800	COG3953	SLT domain
BUN12_RS11900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS11900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN12_RS11950	COG1396	sequence-specific DNA binding
BUN12_RS11965	COG0719	Fe-S assembly protein
BUN12_RS11970	COG0822	iron-sulfur transferase activity
BUN12_RS11975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUN12_RS11980	COG0719	Fe-S assembly protein
BUN12_RS11985	COG0396	ATPase activity
BUN12_RS12000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUN12_RS12005	COG1464	Belongs to the NlpA lipoprotein family
BUN12_RS12010	COG2011	ABC-type metal ion transport system permease component
BUN12_RS12015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUN12_RS12025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS12045	COG1393	Belongs to the ArsC family
BUN12_RS12050	COG1960	acyl-CoA dehydrogenase activity
BUN12_RS12055	COG0183	Belongs to the thiolase family
BUN12_RS12060	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUN12_RS12060	COG1024	Enoyl-CoA hydratase
BUN12_RS12080	COG5577	PFAM Coat F domain
BUN12_RS12085	COG1846	Transcriptional regulator
BUN12_RS12090	COG0477	Major facilitator Superfamily
BUN12_RS12120	COG1120	ATPase activity
BUN12_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS12140	COG0783	Belongs to the Dps family
BUN12_RS12145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_RS12150	COG0745	RESPONSE REGULATOR receiver
BUN12_RS12155	COG2770	Histidine kinase
BUN12_RS12155	COG2205	protein histidine kinase activity
BUN12_RS12165	COG1309	transcriptional regulator
BUN12_RS12170	COG0114	fumarate hydratase activity
BUN12_RS12180	COG0697	spore germination
BUN12_RS12185	COG0814	amino acid
BUN12_RS12195	COG2197	response regulator
BUN12_RS12200	COG4585	Histidine kinase
BUN12_RS12205	COG4758	membrane
BUN12_RS12210	COG3595	metallopeptidase activity
BUN12_RS12215	COG1842	Phage shock protein A
BUN12_RS12220	COG4758	membrane
BUN12_RS12225	COG2814	Major facilitator Superfamily
BUN12_RS12230	COG2096	Adenosyltransferase
BUN12_RS12235	COG1120	ATPase activity
BUN12_RS12240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS12245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS12255	COG3386	PFAM SMP-30 Gluconolaconase
BUN12_RS12260	COG2205	protein histidine kinase activity
BUN12_RS12265	COG0745	RESPONSE REGULATOR receiver
BUN12_RS12275	COG1191	sigma factor activity
BUN12_RS12285	COG2140	Oxalate decarboxylase
BUN12_RS12295	COG1120	ATPase activity
BUN12_RS12300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS12305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS12310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_RS12315	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BUN12_RS12320	COG0531	amino acid
BUN12_RS12335	COG1988	membrane-bound metal-dependent
BUN12_RS12345	COG1910	domain protein
BUN12_RS12350	COG0725	ABC transporter, periplasmic molybdate-binding protein
BUN12_RS12355	COG4149	molybdate abc transporter
BUN12_RS12360	COG2197	response regulator
BUN12_RS12370	COG1131	(ABC) transporter
BUN12_RS12380	COG0842	Transport permease protein
BUN12_RS12385	COG0656	L-ascorbic acid biosynthetic process
BUN12_RS12410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_RS12420	COG2860	membrane
BUN12_RS12430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BUN12_RS12435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BUN12_RS12440	COG2217	Heavy metal translocating P-type atpase
BUN12_RS12445	COG2217	Heavy metal translocating P-type atpase
BUN12_RS12450	COG2608	mercury ion transmembrane transporter activity
BUN12_RS12455	COG1937	Protein conserved in bacteria
BUN12_RS12460	COG0673	inositol 2-dehydrogenase activity
BUN12_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS12475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BUN12_RS12480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS12485	COG1126	abc transporter atp-binding protein
BUN12_RS12490	COG0765	amino acid transport
BUN12_RS12495	COG0765	amino acid transport
BUN12_RS12500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS12505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS12510	COG0454	-acetyltransferase
BUN12_RS12515	COG0583	DNA-binding transcription factor activity
BUN12_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS12525	COG2732	(Barnase) inhibitor
BUN12_RS12540	COG0557	exoribonuclease II activity
BUN12_RS12545	COG1647	Serine aminopeptidase, S33
BUN12_RS12550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUN12_RS12555	COG1476	TRANSCRIPTIONal
BUN12_RS12560	COG1396	sequence-specific DNA binding
BUN12_RS12565	COG1396	sequence-specific DNA binding
BUN12_RS12570	COG1733	regulation of RNA biosynthetic process
BUN12_RS12595	COG1131	(ABC) transporter
BUN12_RS12600	COG1174	glycine betaine transport
BUN12_RS12605	COG1732	Glycine betaine
BUN12_RS12610	COG1174	glycine betaine transport
BUN12_RS12615	COG0517	IMP dehydrogenase activity
BUN12_RS12615	COG1125	glycine betaine transport
BUN12_RS12620	COG1510	regulation of RNA biosynthetic process
BUN12_RS12625	COG1174	glycine betaine transport
BUN12_RS12630	COG1732	Glycine betaine
BUN12_RS12635	COG1174	glycine betaine transport
BUN12_RS12640	COG1125	glycine betaine transport
BUN12_RS12640	COG0517	IMP dehydrogenase activity
BUN12_RS12645	COG1510	regulation of RNA biosynthetic process
BUN12_RS12650	COG2095	MarC family integral membrane protein
BUN12_RS12655	COG3064	Membrane
BUN12_RS12660	COG4640	response to antibiotic
BUN12_RS12665	COG0456	acetyltransferase
BUN12_RS12680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUN12_RS12700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_RS12705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_RS12715	COG2234	aminopeptidase activity
BUN12_RS12735	COG0126	phosphoglycerate kinase activity
BUN12_RS12745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUN12_RS12750	COG2390	Transcriptional regulator
BUN12_RS12760	COG1609	Transcriptional regulator
BUN12_RS12765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS12775	COG0697	spore germination
BUN12_RS12780	COG1113	amino acid transport
BUN12_RS12785	COG1737	Transcriptional regulator
BUN12_RS12790	COG1070	Carbohydrate kinase
BUN12_RS12815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS12820	COG2186	Transcriptional regulator
BUN12_RS12825	COG1620	l-lactate permease
BUN12_RS12830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUN12_RS12840	COG5039	Polysaccharide pyruvyl transferase
BUN12_RS12845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_RS12850	COG0110	maltose O-acetyltransferase activity
BUN12_RS12855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUN12_RS12860	COG2244	polysaccharide biosynthetic process
BUN12_RS12865	COG1216	Glycosyl transferase, family 2
BUN12_RS12870	COG5039	Polysaccharide pyruvyl transferase
BUN12_RS12875	COG1216	Glycosyl transferase, family 2
BUN12_RS12885	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS12890	COG1215	transferase activity, transferring glycosyl groups
BUN12_RS12895	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS12900	COG1086	Polysaccharide biosynthesis protein
BUN12_RS12905	COG0489	protein tyrosine kinase activity
BUN12_RS12910	COG3944	biosynthesis protein
BUN12_RS12915	COG1396	sequence-specific DNA binding
BUN12_RS12920	COG2272	Belongs to the type-B carboxylesterase lipase family
BUN12_RS12930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUN12_RS12945	COG2364	Membrane
BUN12_RS12950	COG0456	acetyltransferase
BUN12_RS12955	COG3479	Phenolic acid decarboxylase
BUN12_RS13005	COG2223	nitrite transmembrane transporter activity
BUN12_RS13010	COG1609	Transcriptional regulator
BUN12_RS13020	COG0583	DNA-binding transcription factor activity
BUN12_RS13025	COG2828	Protein conserved in bacteria
BUN12_RS13030	COG0477	Major facilitator Superfamily
BUN12_RS13030	COG2814	Major facilitator Superfamily
BUN12_RS13040	COG1611	Belongs to the LOG family
BUN12_RS13045	COG1694	Mazg nucleotide pyrophosphohydrolase
BUN12_RS13050	COG0659	secondary active sulfate transmembrane transporter activity
BUN12_RS13055	COG0288	reversible hydration of carbon dioxide
BUN12_RS13065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN12_RS13070	COG4290	ribonuclease
BUN12_RS13075	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BUN12_RS13080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS13090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BUN12_RS13100	COG1051	belongs to the nudix hydrolase family
BUN12_RS13105	COG0492	ferredoxin-NADP+ reductase activity
BUN12_RS13110	COG3883	PFAM NLP P60 protein
BUN12_RS13110	COG0791	NLP P60 protein
BUN12_RS13115	COG0457	Tetratricopeptide repeat
BUN12_RS13120	COG5002	protein histidine kinase activity
BUN12_RS13125	COG0745	RESPONSE REGULATOR receiver
BUN12_RS13130	COG1132	(ABC) transporter
BUN12_RS13135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BUN12_RS13135	COG0140	phosphoribosyl-ATP diphosphatase activity
BUN12_RS13160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BUN12_RS13175	COG4990	cell redox homeostasis
BUN12_RS13180	COG0110	maltose O-acetyltransferase activity
BUN12_RS13200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUN12_RS13210	COG2188	Transcriptional regulator
BUN12_RS13215	COG1309	transcriptional regulator
BUN12_RS13220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BUN12_RS13225	COG1950	PFAM Membrane protein of
BUN12_RS13230	COG1983	PspC domain protein
BUN12_RS13235	COG3595	metallopeptidase activity
BUN12_RS13250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BUN12_RS13260	COG4897	Protein conserved in bacteria
BUN12_RS13265	COG0574	Belongs to the PEP-utilizing enzyme family
BUN12_RS13265	COG3848	Pyruvate phosphate dikinase
BUN12_RS13270	COG1309	transcriptional regulator
BUN12_RS13275	COG2814	Major facilitator Superfamily
BUN12_RS13290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_RS13300	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS13300	COG0793	Belongs to the peptidase S41A family
BUN12_RS13305	COG3420	alginic acid biosynthetic process
BUN12_RS13310	COG2177	Part of the ABC transporter FtsEX involved in
BUN12_RS13315	COG2884	Cell division ATP-binding protein ftsE
BUN12_RS13320	COG2010	Cytochrome c
BUN12_RS13325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS13340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BUN12_RS13355	COG1516	flagellar protein fliS
BUN12_RS13360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BUN12_RS13365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUN12_RS13385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUN12_RS13390	COG1256	bacterial-type flagellum assembly
BUN12_RS13390	COG4786	Flagellar basal body rod
BUN12_RS13395	COG3418	PFAM FlgN family protein
BUN12_RS13400	COG2747	anti-sigma28 factor FlgM
BUN12_RS13410	COG1040	competence protein
BUN12_RS13420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BUN12_RS13425	COG1307	EDD domain protein, DegV family
BUN12_RS13430	COG2197	response regulator
BUN12_RS13435	COG4585	Histidine kinase
BUN12_RS13440	COG1739	Uncharacterized protein family UPF0029
BUN12_RS13445	COG1316	TRANSCRIPTIONal
BUN12_RS13450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN12_RS13455	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS13460	COG1215	transferase activity, transferring glycosyl groups
BUN12_RS13465	COG3206	protein involved in exopolysaccharide biosynthesis
BUN12_RS13470	COG3307	-O-antigen
BUN12_RS13475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUN12_RS13480	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS13480	COG0297	glycogen (starch) synthase activity
BUN12_RS13485	COG2244	polysaccharide biosynthetic process
BUN12_RS13495	COG2247	cell wall binding repeat
BUN12_RS13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS13500	COG2247	cell wall binding repeat
BUN12_RS13500	COG2385	sporulation resulting in formation of a cellular spore
BUN12_RS13510	COG1316	TRANSCRIPTIONal
BUN12_RS13515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUN12_RS13520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUN12_RS13525	COG1134	teichoic acid transport
BUN12_RS13530	COG1682	transport, permease protein
BUN12_RS13535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_RS13540	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS13545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BUN12_RS13550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BUN12_RS13555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_RS13560	COG4193	domain, Protein
BUN12_RS13565	COG1482	cell wall glycoprotein biosynthetic process
BUN12_RS13570	COG0697	spore germination
BUN12_RS13575	COG0814	amino acid
BUN12_RS13590	COG1215	transferase activity, transferring glycosyl groups
BUN12_RS13595	COG2814	Major facilitator Superfamily
BUN12_RS13600	COG1316	TRANSCRIPTIONal
BUN12_RS13605	COG0561	phosphatase activity
BUN12_RS13610	COG2433	Pfam Transposase IS66
BUN12_RS13615	COG0791	NLP P60 protein
BUN12_RS13630	COG2843	Capsule synthesis protein
BUN12_RS13640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BUN12_RS13650	COG0697	spore germination
BUN12_RS13655	COG0814	amino acid
BUN12_RS13665	COG1609	Transcriptional regulator
BUN12_RS13670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_RS13680	COG1129	ABC transporter
BUN12_RS13685	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUN12_RS13690	COG1879	ABC-type sugar transport system periplasmic component
BUN12_RS13695	COG3103	Sh3 type 3 domain protein
BUN12_RS13700	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUN12_RS13705	COG3527	Alpha-acetolactate decarboxylase
BUN12_RS13710	COG0028	Belongs to the TPP enzyme family
BUN12_RS13715	COG0583	DNA-binding transcription factor activity
BUN12_RS13720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUN12_RS13735	COG5337	Spore coat protein CotH
BUN12_RS13745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BUN12_RS13755	COG0405	Gamma-glutamyltransferase
BUN12_RS13760	COG1522	sequence-specific DNA binding
BUN12_RS13765	COG2059	Chromate
BUN12_RS13770	COG2059	Chromate
BUN12_RS13805	COG5444	nuclease activity
BUN12_RS13820	COG3878	Protein conserved in bacteria
BUN12_RS13825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUN12_RS13830	COG4464	protein tyrosine phosphatase activity
BUN12_RS13835	COG0489	protein tyrosine kinase activity
BUN12_RS13840	COG3944	biosynthesis protein
BUN12_RS13855	COG4715	Zinc finger, swim domain protein
BUN12_RS13860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUN12_RS13865	COG0561	phosphatase activity
BUN12_RS13870	COG1349	DNA-binding transcription factor activity
BUN12_RS13875	COG0629	single-stranded DNA binding
BUN12_RS13900	COG0457	Tetratricopeptide repeat
BUN12_RS13905	COG4786	Flagellar basal body rod
BUN12_RS13915	COG1077	Cell shape determining protein MreB Mrl
BUN12_RS13920	COG1609	Transcriptional regulator
BUN12_RS13925	COG1846	Transcriptional regulator
BUN12_RS13930	COG2814	Major facilitator Superfamily
BUN12_RS13935	COG1953	Uracil, thiamine, allantoin
BUN12_RS13940	COG0477	Major facilitator Superfamily
BUN12_RS13945	COG1335	isochorismatase
BUN12_RS13950	COG0004	ammonium transporteR
BUN12_RS13955	COG0347	Belongs to the P(II) protein family
BUN12_RS13960	COG0772	Belongs to the SEDS family
BUN12_RS13965	COG0671	phosphoesterase, PA-phosphatase related
BUN12_RS13975	COG0739	heme binding
BUN12_RS13980	COG1247	-acetyltransferase
BUN12_RS13995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS14010	COG2910	NAD(P)H-binding
BUN12_RS14015	COG1959	2 iron, 2 sulfur cluster binding
BUN12_RS14030	COG0831	urea catabolic process
BUN12_RS14035	COG3237	CsbD-like
BUN12_RS14040	COG1994	Peptidase M50
BUN12_RS14045	COG0457	Tetratricopeptide repeat
BUN12_RS14055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BUN12_RS14060	COG2304	oxidoreductase activity
BUN12_RS14065	COG2304	oxidoreductase activity
BUN12_RS14070	COG2385	sporulation resulting in formation of a cellular spore
BUN12_RS14075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUN12_RS14085	COG4836	Membrane
BUN12_RS14155	COG0698	ribose 5-phosphate isomerase
BUN12_RS14160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUN12_RS14170	COG0009	L-threonylcarbamoyladenylate synthase
BUN12_RS14175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BUN12_RS14195	COG2890	protein-(glutamine-N5) methyltransferase activity
BUN12_RS14200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BUN12_RS14205	COG0346	lactoylglutathione lyase activity
BUN12_RS14210	COG0789	Transcriptional regulator
BUN12_RS14215	COG0679	Auxin Efflux Carrier
BUN12_RS14220	COG0281	malic enzyme
BUN12_RS14235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BUN12_RS14240	COG1494	fructose-1,6-bisphosphatase
BUN12_RS14245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUN12_RS14255	COG0191	fructose-bisphosphate aldolase activity
BUN12_RS14260	COG2204	response regulator
BUN12_RS14265	COG4821	SIS domain
BUN12_RS14280	COG2181	nitrate reductase activity
BUN12_RS14280	COG0247	lactate metabolic process
BUN12_RS14285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS14300	COG1132	(ABC) transporter
BUN12_RS14305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS14310	COG2181	nitrate reductase activity
BUN12_RS14315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BUN12_RS14320	COG1140	nitrate reductase beta subunit
BUN12_RS14325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BUN12_RS14330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_RS14340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN12_RS14345	COG2223	nitrite transmembrane transporter activity
BUN12_RS14355	COG4506	Protein conserved in bacteria
BUN12_RS14375	COG0457	Tetratricopeptide repeat
BUN12_RS14385	COG0010	Belongs to the arginase family
BUN12_RS14390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUN12_RS14395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN12_RS14410	COG1994	Peptidase M50
BUN12_RS14415	COG1942	4-Oxalocrotonate Tautomerase
BUN12_RS14420	COG1846	Transcriptional regulator
BUN12_RS14430	COG0531	amino acid
BUN12_RS14435	COG3465	dGTPase activity
BUN12_RS14440	COG1078	dGTPase activity
BUN12_RS14455	COG1695	Transcriptional regulator
BUN12_RS14465	COG1131	(ABC) transporter
BUN12_RS14470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_RS14500	COG0583	DNA-binding transcription factor activity
BUN12_RS14505	COG2855	membrane
BUN12_RS14510	COG0280	phosphate acetyltransferase
BUN12_RS14530	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS14535	COG0436	Aminotransferase
BUN12_RS14545	COG0151	Belongs to the GarS family
BUN12_RS14555	COG1917	Cupin 2, conserved barrel domain protein
BUN12_RS14565	COG2814	Major facilitator Superfamily
BUN12_RS14570	COG2814	Major facilitator Superfamily
BUN12_RS14575	COG0833	amino acid
BUN12_RS14580	COG4187	Peptidase family M20/M25/M40
BUN12_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS14590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN12_RS14600	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BUN12_RS14605	COG1091	dTDP-4-dehydrorhamnose reductase activity
BUN12_RS14610	COG1088	dTDP-glucose 4,6-dehydratase activity
BUN12_RS14615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BUN12_RS14620	COG3980	spore coat polysaccharide biosynthesis protein
BUN12_RS14625	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BUN12_RS14630	COG2089	acid synthase
BUN12_RS14635	COG0456	acetyltransferase
BUN12_RS14640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN12_RS14645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN12_RS14650	COG0463	Glycosyl transferase, family 2
BUN12_RS14660	COG2363	Small membrane protein
BUN12_RS14665	COG2233	PERMEase
BUN12_RS14680	COG1216	Glycosyl transferase, family 2
BUN12_RS14690	COG0351	phosphomethylpyrimidine kinase
BUN12_RS14700	COG1621	beta-fructofuranosidase activity
BUN12_RS14705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS14705	COG1263	PTS System
BUN12_RS14710	COG3711	transcriptional antiterminator
BUN12_RS14720	COG1404	Belongs to the peptidase S8 family
BUN12_RS14725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS14730	COG2378	regulation of single-species biofilm formation
BUN12_RS14750	COG0778	Nitroreductase
BUN12_RS14755	COG0772	Belongs to the SEDS family
BUN12_RS14760	COG0454	-acetyltransferase
BUN12_RS14780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUN12_RS14785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BUN12_RS14790	COG2261	transglycosylase associated protein
BUN12_RS14795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUN12_RS14800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUN12_RS14805	COG2246	polysaccharide biosynthetic process
BUN12_RS14810	COG1309	transcriptional regulator
BUN12_RS14830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUN12_RS14835	COG2837	iron assimilation
BUN12_RS14840	COG2822	iron ion transport
BUN12_RS14845	COG0672	)-iron permease
BUN12_RS14860	COG0583	DNA-binding transcription factor activity
BUN12_RS14870	COG1346	cytolysis
BUN12_RS14875	COG4895	conserved protein (DUF2196)
BUN12_RS14880	COG0789	Transcriptional regulator
BUN12_RS14885	COG5504	Zn-dependent protease
BUN12_RS14890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUN12_RS14895	COG0346	lactoylglutathione lyase activity
BUN12_RS14900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS14905	COG1404	Belongs to the peptidase S8 family
BUN12_RS14910	COG1442	glycosyl transferase family 8
BUN12_RS14915	COG2357	RelA SpoT domain protein
BUN12_RS14920	COG1575	Belongs to the MenA family. Type 1 subfamily
BUN12_RS14945	COG1696	Membrane protein involved in D-alanine export
BUN12_RS14955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BUN12_RS14960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS14965	COG1486	melibiose metabolic process
BUN12_RS14970	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_RS14975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS14980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS14985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS14985	COG3711	transcriptional antiterminator
BUN12_RS15000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS15005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS15015	COG0640	Transcriptional regulator
BUN12_RS15020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUN12_RS15025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS15030	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUN12_RS15035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUN12_RS15040	COG2723	6-phospho-beta-galactosidase activity
BUN12_RS15045	COG1940	carbohydrate kinase activity
BUN12_RS15050	COG1482	cell wall glycoprotein biosynthetic process
BUN12_RS15060	COG0753	catalase activity
BUN12_RS15065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BUN12_RS15070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUN12_RS15080	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BUN12_RS15085	COG4988	ABC transporter
BUN12_RS15090	COG1294	oxidase, subunit
BUN12_RS15095	COG1271	oxidase subunit
BUN12_RS15100	COG3493	citrate carrier protein
BUN12_RS15105	COG0726	polysaccharide deacetylase
BUN12_RS15110	COG3842	ATPase activity
BUN12_RS15115	COG2508	Transcriptional regulator
BUN12_RS15120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS15130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUN12_RS15140	COG4894	glucomannan catabolic process
BUN12_RS15145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUN12_RS15150	COG0500	methyltransferase
BUN12_RS15155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_RS15175	COG0753	catalase activity
BUN12_RS15175	COG0693	protein deglycase activity
BUN12_RS15185	COG2273	Hydrolase Family 16
BUN12_RS15190	COG3711	transcriptional antiterminator
BUN12_RS15195	COG2270	Major facilitator Superfamily
BUN12_RS15200	COG0513	Belongs to the DEAD box helicase family
BUN12_RS15245	COG0697	spore germination
BUN12_RS15250	COG0589	response to stress
BUN12_RS15255	COG2723	6-phospho-beta-galactosidase activity
BUN12_RS15260	COG2190	(PTS) system
BUN12_RS15260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS15260	COG1263	PTS System
BUN12_RS15275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BUN12_RS15300	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN12_RS15325	COG0010	Belongs to the arginase family
BUN12_RS15330	COG0833	amino acid
BUN12_RS15335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BUN12_RS15340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUN12_RS15350	COG2390	Transcriptional regulator
BUN12_RS15355	COG0561	phosphatase activity
BUN12_RS15385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_RS15390	COG5294	Protein conserved in bacteria
BUN12_RS15395	COG0577	efflux transmembrane transporter activity
BUN12_RS15400	COG1136	(ABC) transporter
BUN12_RS15405	COG2205	protein histidine kinase activity
BUN12_RS15410	COG0745	RESPONSE REGULATOR receiver
BUN12_RS15425	COG1082	Xylose isomerase domain protein TIM barrel
BUN12_RS15435	COG2814	Major facilitator Superfamily
BUN12_RS15465	COG1349	DNA-binding transcription factor activity
BUN12_RS15470	COG0667	Aldo Keto reductase
BUN12_RS15475	COG2814	Major facilitator Superfamily
BUN12_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS15490	COG2197	response regulator
BUN12_RS15495	COG4585	Histidine kinase
BUN12_RS15500	COG3239	Fatty acid desaturase
BUN12_RS15505	COG1309	transcriptional regulator
BUN12_RS15510	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS15515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BUN12_RS15525	COG0640	Transcriptional regulator
BUN12_RS15530	COG2814	Major facilitator Superfamily
BUN12_RS15535	COG1714	RDD family
BUN12_RS15545	COG0450	alkyl hydroperoxide reductase
BUN12_RS15550	COG3634	alkyl hydroperoxide reductase activity
BUN12_RS15560	COG1113	amino acid transport
BUN12_RS15615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN12_RS15630	COG2323	membrane
BUN12_RS15640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN12_RS15645	COG2323	membrane
BUN12_RS15655	COG2080	2 iron, 2 sulfur cluster binding
BUN12_RS15665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BUN12_RS15670	COG2068	MobA-Related Protein
BUN12_RS15675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BUN12_RS15725	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BUN12_RS15730	COG0667	Aldo Keto reductase
BUN12_RS15735	COG0456	acetyltransferase
BUN12_RS15740	COG0457	Tetratricopeptide repeat
BUN12_RS15745	COG0010	Belongs to the arginase family
BUN12_RS15750	COG0833	amino acid
BUN12_RS15755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUN12_RS15760	COG5658	integral membrane protein
BUN12_RS15765	COG0640	Transcriptional regulator
BUN12_RS15770	COG3829	transcription factor binding
BUN12_RS15785	COG5002	protein histidine kinase activity
BUN12_RS15785	COG3850	Histidine kinase
BUN12_RS15790	COG0745	RESPONSE REGULATOR receiver
BUN12_RS15800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN12_RS15805	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUN12_RS15810	COG4853	Protein conserved in bacteria
BUN12_RS15815	COG4863	YycH protein
BUN12_RS15820	COG5002	protein histidine kinase activity
BUN12_RS15825	COG0745	RESPONSE REGULATOR receiver
BUN12_RS15860	COG0346	lactoylglutathione lyase activity
BUN12_RS15865	COG0305	Participates in initiation and elongation during chromosome replication
BUN12_RS15880	COG3093	addiction module antidote protein HigA
BUN12_RS15895	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BUN12_RS15900	COG0438	transferase activity, transferring glycosyl groups
BUN12_RS15920	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BUN12_RS15925	COG4241	membrane
BUN12_RS15935	COG5577	PFAM Coat F domain
BUN12_RS15940	COG1733	regulation of RNA biosynthetic process
BUN12_RS15950	COG0697	spore germination
BUN12_RS15955	COG1621	beta-fructofuranosidase activity
BUN12_RS15960	COG1621	beta-fructofuranosidase activity
BUN12_RS15970	COG2318	DinB family
BUN12_RS15975	COG2211	Major facilitator Superfamily
BUN12_RS15985	COG0778	Nitroreductase
BUN12_RS15990	COG1846	Transcriptional regulator
BUN12_RS15995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS16000	COG1846	Transcriptional regulator
BUN12_RS16005	COG2153	protein acetylation
BUN12_RS16010	COG0640	Transcriptional regulator
BUN12_RS16015	COG2267	carboxylic ester hydrolase activity
BUN12_RS16040	COG1266	CAAX protease self-immunity
BUN12_RS16045	COG0477	Major facilitator Superfamily
BUN12_RS16045	COG2814	Major facilitator Superfamily
BUN12_RS16050	COG0346	lactoylglutathione lyase activity
BUN12_RS16060	COG0708	Exodeoxyribonuclease III
BUN12_RS16065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUN12_RS16070	COG2169	Transcriptional regulator
BUN12_RS16080	COG0629	single-stranded DNA binding
BUN12_RS16090	COG0012	GTP binding
BUN12_RS16095	COG0243	molybdopterin cofactor binding
BUN12_RS16100	COG4481	Protein conserved in bacteria
BUN12_RS16105	COG3949	Membrane
BUN12_RS16120	COG1475	DNA binding
BUN12_RS16125	COG1192	Involved in chromosome partitioning
BUN12_RS16150	COG1847	R3H domain protein
BUN12_RS16155	COG0706	membrane insertase activity
BUN12_RS16175	COG0592	DNA-directed DNA polymerase activity
BUN12_RS16180	COG2501	S4 domain
BUN12_RS16195	COG0187	DNA topoisomerase II activity
BUN12_RS16200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUN12_RS16235	COG0517	IMP dehydrogenase activity
BUN12_RS16235	COG0516	GMP reductase activity
BUN12_RS16240	COG1686	Belongs to the peptidase S11 family
BUN12_RS16260	COG1929	Belongs to the glycerate kinase type-1 family
BUN12_RS16270	COG1428	Deoxynucleoside kinase
BUN12_RS16275	COG1428	Deoxynucleoside kinase
BUN12_RS16280	COG3858	chitin binding
BUN12_RS16280	COG1388	LysM domain
BUN12_RS16285	COG1335	isochorismatase
BUN12_RS16290	COG0590	tRNA wobble adenosine to inosine editing
BUN12_RS16300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUN12_RS16305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BUN12_RS16355	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BUN12_RS16360	COG3853	Toxic anion resistance protein (TelA)
BUN12_RS16365	COG1982	Orn Lys Arg decarboxylase major
BUN12_RS16375	COG3870	Protein conserved in bacteria
BUN12_RS16380	COG1728	Protein conserved in bacteria
BUN12_RS16385	COG0470	DNA polymerase III
BUN12_RS16390	COG1774	PSP1 C-terminal conserved region
BUN12_RS16400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUN12_RS16410	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUN12_RS16415	COG2002	toxin-antitoxin pair type II binding
BUN12_RS16420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_RS16420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN12_RS16425	COG0084	hydrolase, TatD family'
BUN12_RS16430	COG3583	domain protein
BUN12_RS16430	COG3584	3D domain protein
BUN12_RS16435	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUN12_RS16440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BUN12_RS16450	COG4466	Protein conserved in bacteria
BUN12_RS16465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUN12_RS16470	COG0251	oxidation-reduction process
BUN12_RS16485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUN12_RS16505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUN12_RS16510	COG2002	toxin-antitoxin pair type II binding
BUN12_RS16515	COG2244	polysaccharide biosynthetic process
BUN12_RS16520	COG3956	TIGRFAM MazG family protein
BUN12_RS16525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUN12_RS16540	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BUN12_RS16545	COG1098	S1 RNA binding domain
BUN12_RS16560	COG2208	phosphoserine phosphatase activity
BUN12_RS16565	COG2304	oxidoreductase activity
BUN12_RS16570	COG0515	serine threonine protein kinase
BUN12_RS16575	COG0037	tRNA processing
BUN12_RS16580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BUN12_RS16585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUN12_RS16600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUN12_RS16605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN12_RS16610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN12_RS16615	COG0512	Glutamine amidotransferase of anthranilate synthase
BUN12_RS16620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS16625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUN12_RS16630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUN12_RS16635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUN12_RS16640	COG1396	sequence-specific DNA binding
BUN12_RS16645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUN12_RS16650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BUN12_RS16730	COG4463	regulation of RNA biosynthetic process
BUN12_RS16735	COG3880	PFAM UvrB UvrC protein
BUN12_RS16745	COG0542	response to heat
BUN12_RS16750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUN12_RS16755	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BUN12_RS16760	COG4956	integral membrane protein (PIN domain superfamily)
BUN12_RS16780	COG1045	serine acetyltransferase
BUN12_RS16790	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BUN12_RS16795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUN12_RS16800	COG3688	RNA-binding protein containing a PIN domain
BUN12_RS16805	COG1595	DNA-templated transcription, initiation
BUN12_RS16815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUN12_RS16820	COG0250	Participates in transcription elongation, termination and antitermination
BUN12_RS16845	COG2813	Specifically methylates the guanine in position
BUN12_RS16860	COG1358	cellular component organization or biogenesis
BUN12_RS16885	COG0596	Alpha beta hydrolase
BUN12_RS16995	COG0201	protein transport
BUN12_RS17005	COG0024	Methionine aminopeptidase
BUN12_RS17020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUN12_RS17045	COG1122	ATPase activity
BUN12_RS17050	COG1122	ATPase activity
BUN12_RS17055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUN12_RS17065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUN12_RS17075	COG2226	methyltransferase
BUN12_RS17085	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS17090	COG0489	protein tyrosine kinase activity
BUN12_RS17100	COG2194	sulfuric ester hydrolase activity
BUN12_RS17105	COG0726	polysaccharide deacetylase
BUN12_RS17165	COG0738	Major facilitator superfamily
BUN12_RS17170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS17185	COG0659	secondary active sulfate transmembrane transporter activity
BUN12_RS17190	COG0385	Bile acid
BUN12_RS17195	COG2819	hydrolase of the alpha beta superfamily
BUN12_RS17200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS17210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_RS17215	COG2207	Transcriptional regulator
BUN12_RS17215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN12_RS17220	COG3876	Protein conserved in bacteria
BUN12_RS17225	COG1472	Belongs to the glycosyl hydrolase 3 family
BUN12_RS17230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_RS17235	COG1263	PTS System
BUN12_RS17235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS17250	COG1683	Conserved Protein
BUN12_RS17285	COG5662	AntiSigma factor
BUN12_RS17290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUN12_RS17295	COG4856	YbbR-like protein
BUN12_RS17345	COG1346	cytolysis
BUN12_RS17350	COG1380	Effector of murein hydrolase LrgA
BUN12_RS17355	COG1846	Transcriptional regulator
BUN12_RS17360	COG1113	amino acid transport
BUN12_RS17365	COG1011	Hydrolase
BUN12_RS17370	COG4585	Histidine kinase
BUN12_RS17375	COG2197	response regulator
BUN12_RS17380	COG1131	(ABC) transporter
BUN12_RS17390	COG1511	domain protein
BUN12_RS17390	COG0842	Transport permease protein
BUN12_RS17420	COG0531	amino acid
BUN12_RS17435	COG0584	glycerophosphoryl diester phosphodiesterase
BUN12_RS17440	COG2271	Major facilitator Superfamily
BUN12_RS17455	COG2368	4-hydroxyphenylacetate
BUN12_RS17470	COG0371	Dehydrogenase
BUN12_RS17480	COG1183	phosphatidylcholine synthase activity
BUN12_RS17485	COG0586	Pfam SNARE associated Golgi protein
BUN12_RS17490	COG0688	phosphatidylethanolamine metabolic process
BUN12_RS17505	COG1301	dicarboxylic acid transport
BUN12_RS17510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS17515	COG0833	amino acid
BUN12_RS17520	COG2040	homocysteine
BUN12_RS17525	COG1115	amino acid carrier protein
BUN12_RS17535	COG4191	Histidine kinase
BUN12_RS17540	COG0784	Response regulator, receiver
BUN12_RS17545	COG3173	Aminoglycoside phosphotransferase
BUN12_RS17555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_RS17565	COG3540	Alkaline phosphatase
BUN12_RS17570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUN12_RS17575	COG0805	protein transport
BUN12_RS17580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BUN12_RS17585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUN12_RS17590	COG0477	Major facilitator Superfamily
BUN12_RS17595	COG1309	transcriptional regulator
BUN12_RS17605	COG1405	negative regulation of cell septum assembly
BUN12_RS17605	COG3012	SEC-C Motif Domain Protein
BUN12_RS17610	COG0667	Aldo Keto reductase
BUN12_RS17620	COG1595	DNA-templated transcription, initiation
BUN12_RS17625	COG1595	DNA-templated transcription, initiation
BUN12_RS17630	COG1876	peptidase activity
BUN12_RS17635	COG0457	Tetratricopeptide repeat
BUN12_RS17640	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS17645	COG0366	Alpha amylase catalytic
BUN12_RS17655	COG1695	Transcriptional regulator
BUN12_RS17660	COG0803	Belongs to the bacterial solute-binding protein 9 family
BUN12_RS17665	COG1121	(ABC) transporter
BUN12_RS17670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUN12_RS17675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS17680	COG2310	stress, protein
BUN12_RS17685	COG2310	stress, protein
BUN12_RS17690	COG2310	stress, protein
BUN12_RS17695	COG0861	Integral membrane protein TerC family
BUN12_RS17705	COG3853	Toxic anion resistance protein (TelA)
BUN12_RS17710	COG0477	Major facilitator Superfamily
BUN12_RS17715	COG0517	IMP dehydrogenase activity
BUN12_RS17715	COG4175	Glycine betaine
BUN12_RS17720	COG4176	ABC-type proline glycine betaine transport system permease component
BUN12_RS17725	COG2113	Glycine betaine
BUN12_RS17730	COG1473	amidohydrolase
BUN12_RS17745	COG1714	RDD family
BUN12_RS17755	COG2814	Major facilitator Superfamily
BUN12_RS17760	COG1846	Transcriptional regulator
BUN12_RS17775	COG3403	YqcI/YcgG family
BUN12_RS17780	COG1113	amino acid transport
BUN12_RS17785	COG3665	Urea carboxylase-associated protein
BUN12_RS17795	COG1082	Xylose isomerase domain protein TIM barrel
BUN12_RS17805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUN12_RS17810	COG3458	cephalosporin-C deacetylase activity
BUN12_RS17815	COG3541	Predicted nucleotidyltransferase
BUN12_RS17820	COG0506	proline dehydrogenase activity
BUN12_RS17825	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS17830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_RS17835	COG2508	Transcriptional regulator
BUN12_RS17845	COG1587	Uroporphyrinogen-III synthase
BUN12_RS17845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BUN12_RS17850	COG2146	nitrite reductase [NAD(P)H] activity
BUN12_RS17855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUN12_RS17865	COG0523	cobalamin synthesis protein
BUN12_RS17870	COG1063	alcohol dehydrogenase
BUN12_RS17875	COG1714	RDD family
BUN12_RS17885	COG2723	6-phospho-beta-galactosidase activity
BUN12_RS17895	COG3209	COG3209 Rhs family protein
BUN12_RS17900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BUN12_RS17905	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUN12_RS17910	COG1733	regulation of RNA biosynthetic process
BUN12_RS17915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS17920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS17925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUN12_RS17930	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BUN12_RS17945	COG2364	Membrane
BUN12_RS17950	COG1126	abc transporter atp-binding protein
BUN12_RS17955	COG0765	amino acid transport
BUN12_RS17960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS17965	COG0583	DNA-binding transcription factor activity
BUN12_RS17970	COG0163	prenyltransferase activity
BUN12_RS17975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BUN12_RS17985	COG3104	oligopeptide transport
BUN12_RS17990	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS18000	COG0697	spore germination
BUN12_RS18010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUN12_RS18015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUN12_RS18020	COG0456	acetyltransferase
BUN12_RS18025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN12_RS18030	COG0765	amino acid transport
BUN12_RS18035	COG1126	abc transporter atp-binding protein
BUN12_RS18040	COG1473	amidohydrolase
BUN12_RS18045	COG2079	MmgE PrpD family protein
BUN12_RS18050	COG1136	(ABC) transporter
BUN12_RS18055	COG0577	efflux transmembrane transporter activity
BUN12_RS18060	COG0745	RESPONSE REGULATOR receiver
BUN12_RS18065	COG5002	protein histidine kinase activity
BUN12_RS18065	COG3850	Histidine kinase
BUN12_RS18070	COG0457	Tetratricopeptide repeat
BUN12_RS18085	COG0527	aspartate kinase activity
BUN12_RS18090	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN12_RS18095	COG4605	iron ion homeostasis
BUN12_RS18100	COG4604	ABC transporter, ATP-binding protein
BUN12_RS18105	COG4607	ABC-type enterochelin transport system periplasmic component
BUN12_RS18110	COG2814	Major facilitator Superfamily
BUN12_RS18115	COG1309	transcriptional regulator
BUN12_RS18120	COG0778	Nitroreductase
BUN12_RS18125	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BUN12_RS18130	COG0640	Transcriptional regulator
BUN12_RS18135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS18140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUN12_RS18145	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS18150	COG4975	Glucose uptake
BUN12_RS18155	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS18160	COG4549	nuclear export factor GLE1
BUN12_RS18165	COG1276	copper resistance
BUN12_RS18165	COG2372	response to copper ion
BUN12_RS18170	COG1349	DNA-binding transcription factor activity
BUN12_RS18180	COG2213	PTS system mannitol-specific
BUN12_RS18185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUN12_RS18195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BUN12_RS18205	COG0561	phosphatase activity
BUN12_RS18215	COG1914	H( )-stimulated, divalent metal cation uptake system
BUN12_RS18225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUN12_RS18230	COG1984	allophanate hydrolase subunit 2
BUN12_RS18235	COG1414	Transcriptional regulator
BUN12_RS18240	COG2755	lipolytic protein G-D-S-L family
BUN12_RS18250	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_RS18255	COG0768	penicillin binding
BUN12_RS18260	COG4989	oxidoreductase activity
BUN12_RS18265	COG3711	transcriptional antiterminator
BUN12_RS18270	COG0318	PFAM AMP-dependent synthetase and ligase
BUN12_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS18285	COG1917	Cupin 2, conserved barrel domain protein
BUN12_RS18290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_RS18295	COG3871	stress protein (general stress protein 26)
BUN12_RS18305	COG2814	Major facilitator Superfamily
BUN12_RS18310	COG1522	sequence-specific DNA binding
BUN12_RS18315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUN12_RS18315	COG0551	DNA topoisomerase type I activity
BUN12_RS18320	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BUN12_RS18325	COG3706	GGDEF domain
BUN12_RS18330	COG5298	Protein conserved in bacteria
BUN12_RS18335	COG1215	transferase activity, transferring glycosyl groups
BUN12_RS18345	COG0531	amino acid
BUN12_RS18350	COG0028	Belongs to the TPP enzyme family
BUN12_RS18385	COG0457	Tetratricopeptide repeat
BUN12_RS18400	COG1914	H( )-stimulated, divalent metal cation uptake system
BUN12_RS18410	COG4876	unkown
BUN12_RS18420	COG2076	Multidrug Resistance protein
BUN12_RS18425	COG2217	Heavy metal translocating P-type atpase
BUN12_RS18430	COG3729	General stress protein
BUN12_RS18435	COG0662	Cupin 2, conserved barrel domain protein
BUN12_RS18440	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_RS18445	COG3546	catalase activity
BUN12_RS18455	COG3290	protein histidine kinase activity
BUN12_RS18460	COG4565	transcriptional regulatory protein
BUN12_RS18465	COG1301	dicarboxylic acid transport
BUN12_RS18470	COG0628	permease
BUN12_RS18475	COG1131	(ABC) transporter
BUN12_RS18480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUN12_RS18490	COG1960	acyl-CoA dehydrogenase activity
BUN12_RS18510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN12_RS18515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN12_RS18525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUN12_RS18530	COG0513	Belongs to the DEAD box helicase family
BUN12_RS18535	COG3402	PFAM membrane-flanked domain
BUN12_RS18540	COG3428	Bacterial PH domain
BUN12_RS18545	COG0705	Rhomboid family
BUN12_RS18555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BUN12_RS18560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUN12_RS18565	COG0864	Transcriptional regulator
BUN12_RS18570	COG2337	Toxic component of a toxin-antitoxin (TA) module
BUN12_RS18575	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS18580	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS18585	COG2172	sigma factor antagonist activity
BUN12_RS18590	COG2208	phosphoserine phosphatase activity
BUN12_RS18595	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS18605	COG1191	sigma factor activity
BUN12_RS18615	COG2183	response to ionizing radiation
BUN12_RS18670	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS18690	COG1191	sigma factor activity
BUN12_RS18710	COG0582	viral genome integration into host DNA
BUN12_RS18715	COG2856	Zn peptidase
BUN12_RS18720	COG1396	sequence-specific DNA binding
BUN12_RS18745	COG1674	ftsk spoiiie
BUN12_RS18750	COG2946	Replication initiation factor
BUN12_RS18800	COG0433	COG0433 Predicted ATPase
BUN12_RS18810	COG5644	endopeptidase inhibitor activity
BUN12_RS18815	COG0741	lytic transglycosylase activity
BUN12_RS18815	COG0791	NLP P60 protein
BUN12_RS18850	COG0457	Tetratricopeptide repeat
BUN12_RS18860	COG5444	nuclease activity
BUN12_RS18875	COG1959	2 iron, 2 sulfur cluster binding
BUN12_RS18885	COG1278	Cold shock
BUN12_RS18890	COG1794	racemase activity, acting on amino acids and derivatives
BUN12_RS18905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS18910	COG0477	Major facilitator Superfamily
BUN12_RS18925	COG0277	FAD linked oxidase domain protein
BUN12_RS18945	COG0662	Cupin 2, conserved barrel domain protein
BUN12_RS18950	COG0456	acetyltransferase
BUN12_RS18955	COG3708	Transcriptional regulator
BUN12_RS18955	COG2207	Transcriptional regulator
BUN12_RS18980	COG1064	alcohol dehydrogenase
BUN12_RS18985	COG0789	Transcriptional regulator
BUN12_RS18995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS19000	COG2808	Putative FMN-binding domain
BUN12_RS19005	COG2814	Major facilitator Superfamily
BUN12_RS19010	COG1309	transcriptional regulator
BUN12_RS19015	COG0697	spore germination
BUN12_RS19020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUN12_RS19025	COG5577	PFAM Coat F domain
BUN12_RS19035	COG1063	alcohol dehydrogenase
BUN12_RS19040	COG5577	PFAM Coat F domain
BUN12_RS19050	COG2409	Drug exporters of the RND superfamily
BUN12_RS19055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUN12_RS19060	COG0488	(ABC) transporter
BUN12_RS19065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN12_RS19070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN12_RS19080	COG2814	Major facilitator Superfamily
BUN12_RS19085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN12_RS19095	COG0730	response to heat
BUN12_RS19100	COG0456	acetyltransferase
BUN12_RS19105	COG0789	Transcriptional regulator
BUN12_RS19105	COG4978	Transcriptional regulator
BUN12_RS19110	COG0697	spore germination
BUN12_RS19115	COG1051	belongs to the nudix hydrolase family
BUN12_RS19120	COG0596	Alpha beta hydrolase
BUN12_RS19125	COG0473	3-isopropylmalate dehydrogenase activity
BUN12_RS19130	COG1802	Transcriptional regulator
BUN12_RS19145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUN12_RS19150	COG1388	LysM domain
BUN12_RS19155	COG2814	Major facilitator Superfamily
BUN12_RS19160	COG2188	Transcriptional regulator
BUN12_RS19165	COG2186	Transcriptional regulator
BUN12_RS19170	COG2807	transmembrane transport
BUN12_RS19175	COG2076	Multidrug Resistance protein
BUN12_RS19180	COG2076	Multidrug Resistance protein
BUN12_RS19185	COG1309	transcriptional regulator
BUN12_RS19190	COG0531	amino acid
BUN12_RS19200	COG3832	glyoxalase III activity
BUN12_RS19205	COG0604	alcohol dehydrogenase
BUN12_RS19210	COG2814	Major facilitator Superfamily
BUN12_RS19255	COG0802	atpase or kinase
BUN12_RS19260	COG1214	PFAM Peptidase M22, glycoprotease
BUN12_RS19265	COG0456	acetyltransferase
BUN12_RS19270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BUN12_RS19275	COG0488	(ABC) transporter
BUN12_RS19290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUN12_RS19295	COG0805	protein transport
BUN12_RS19305	COG1266	CAAX protease self-immunity
BUN12_RS19325	COG2856	Zn peptidase
BUN12_RS19340	COG1396	sequence-specific DNA binding
BUN12_RS19385	COG3723	Recombinational DNA repair protein, rece pathway
BUN12_RS19390	COG3935	DnaD domain protein
BUN12_RS19395	COG1484	DNA-dependent DNA replication
BUN12_RS19490	COG1595	DNA-templated transcription, initiation
BUN12_RS19515	COG5484	DNA packaging
BUN12_RS19520	COG1783	phage Terminase large subunit
BUN12_RS19645	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS19645	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUN12_RS19645	COG1388	LysM domain
BUN12_RS19660	COG3409	Peptidoglycan-binding domain 1 protein
BUN12_RS19675	COG0457	Tetratricopeptide repeat
BUN12_RS19680	COG1063	alcohol dehydrogenase
BUN12_RS19685	COG2211	Major facilitator Superfamily
BUN12_RS19690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN12_RS19700	COG1842	Phage shock protein A
BUN12_RS19705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUN12_RS19710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BUN12_RS19715	COG4260	virion core protein, lumpy skin disease virus
BUN12_RS19720	COG2755	lipolytic protein G-D-S-L family
BUN12_RS19720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BUN12_RS19730	COG1595	DNA-templated transcription, initiation
BUN12_RS19735	COG1063	alcohol dehydrogenase
BUN12_RS19740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BUN12_RS19745	COG0823	Involved in the tonB-independent uptake of proteins
BUN12_RS19755	COG2132	Multicopper oxidase
BUN12_RS19760	COG1113	amino acid transport
BUN12_RS19775	COG0714	Associated with various cellular activities
BUN12_RS19780	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BUN12_RS19785	COG1305	Transglutaminase-like
BUN12_RS19805	COG2252	PERMEase
BUN12_RS19810	COG3064	Membrane
BUN12_RS19830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUN12_RS19835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BUN12_RS19840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BUN12_RS19845	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BUN12_RS19850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUN12_RS19865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUN12_RS19875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUN12_RS19880	COG0138	bifunctional purine biosynthesis protein purh
BUN12_RS19885	COG0151	Belongs to the GarS family
BUN12_RS19890	COG1522	sequence-specific DNA binding
BUN12_RS19895	COG0531	amino acid
BUN12_RS19905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUN12_RS19910	COG1470	cell adhesion involved in biofilm formation
BUN12_RS19915	COG4496	protein, YerC YecD
BUN12_RS19920	COG0069	glutamate synthase activity
BUN12_RS19930	COG0210	DNA helicase
BUN12_RS19940	COG4851	CamS sex pheromone cAM373 precursor
BUN12_RS19945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUN12_RS19950	COG1285	pathogenesis
BUN12_RS19955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN12_RS19975	COG1309	transcriptional regulator
BUN12_RS19980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUN12_RS19985	COG1597	lipid kinase activity
BUN12_RS19990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUN12_RS20005	COG1131	(ABC) transporter
BUN12_RS20035	COG5444	nuclease activity
BUN12_RS20040	COG5444	nuclease activity
BUN12_RS20070	COG3546	catalase activity
BUN12_RS20075	COG0454	-acetyltransferase
BUN12_RS20085	COG2323	membrane
BUN12_RS20090	COG2329	Antibiotic biosynthesis monooxygenase
BUN12_RS20095	COG0346	lactoylglutathione lyase activity
BUN12_RS20100	COG1366	Belongs to the anti-sigma-factor antagonist family
BUN12_RS20105	COG5583	Uncharacterized small protein (DUF2292)
BUN12_RS20110	COG0196	riboflavin kinase activity
BUN12_RS20115	COG0670	Belongs to the BI1 family
BUN12_RS20120	COG1846	Transcriptional regulator
BUN12_RS20125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BUN12_RS20135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUN12_RS20135	COG2124	cytochrome p450
BUN12_RS20145	COG1368	sulfuric ester hydrolase activity
BUN12_RS20150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUN12_RS20155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN12_RS20160	COG1442	glycosyl transferase family 8
BUN12_RS20165	COG1216	Glycosyl transferase, family 2
BUN12_RS20170	COG1442	glycosyl transferase family 8
BUN12_RS20175	COG2223	nitrite transmembrane transporter activity
BUN12_RS20180	COG0531	amino acid
BUN12_RS20185	COG1012	belongs to the aldehyde dehydrogenase family
BUN12_RS20190	COG0840	transmembrane signaling receptor activity
BUN12_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
BUN12_RS20200	COG0457	Tetratricopeptide repeat
BUN12_RS20200	COG0463	Glycosyl transferase, family 2
BUN12_RS20205	COG0488	(ABC) transporter
BUN12_RS20210	COG0789	Transcriptional regulator
BUN12_RS20215	COG2814	Major facilitator Superfamily
BUN12_RS20220	COG0488	(ABC) transporter
BUN12_RS20225	COG0513	Belongs to the DEAD box helicase family
BUN12_RS20245	COG3866	Pectate lyase
BUN12_RS20250	COG0471	metal ion transport
BUN12_RS20270	COG2972	Histidine kinase
BUN12_RS20270	COG0745	RESPONSE REGULATOR receiver
BUN12_RS20285	COG3764	Sortase (surface protein transpeptidase)
BUN12_RS20290	COG3290	protein histidine kinase activity
BUN12_RS20295	COG4565	transcriptional regulatory protein
BUN12_RS20300	COG3181	Tripartite tricarboxylate transporter family receptor
BUN12_RS20305	COG2851	Citrate transporter
BUN12_RS20315	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BUN12_RS20325	COG2258	MOSC domain
BUN12_RS20340	COG0024	Methionine aminopeptidase
BUN12_RS20345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS20345	COG1263	PTS System
BUN12_RS20355	COG1368	sulfuric ester hydrolase activity
BUN12_RS20365	COG0071	Belongs to the small heat shock protein (HSP20) family
BUN12_RS20385	COG0366	Alpha amylase catalytic
BUN12_RS20390	COG2188	Transcriptional regulator
BUN12_RS20395	COG0778	Nitroreductase
BUN12_RS20410	COG0737	Belongs to the 5'-nucleotidase family
BUN12_RS20415	COG0693	protein deglycase activity
BUN12_RS20420	COG1609	Transcriptional regulator
BUN12_RS20435	COG2814	Major facilitator Superfamily
BUN12_RS20445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUN12_RS20450	COG4980	gas vesicle protein
BUN12_RS20455	COG1295	ribonuclease BN
BUN12_RS20460	COG0477	Major facilitator Superfamily
BUN12_RS20465	COG0387	Pfam Sodium calcium exchanger
BUN12_RS20475	COG0668	transmembrane transport
BUN12_RS20480	COG0535	radical SAM domain protein
BUN12_RS20490	COG0726	polysaccharide deacetylase
BUN12_RS20505	COG0598	Magnesium transport protein CorA
BUN12_RS20510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BUN12_RS20515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUN12_RS20530	COG1132	(ABC) transporter
BUN12_RS20535	COG0515	serine threonine protein kinase
BUN12_RS20545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUN12_RS20550	COG4637	Psort location Cytoplasmic, score
BUN12_RS20555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUN12_RS20560	COG0022	dehydrogenase e1 component
BUN12_RS20565	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN12_RS20570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN12_RS20575	COG3284	Transcriptional regulator
BUN12_RS20585	COG1486	melibiose metabolic process
BUN12_RS20590	COG1737	Transcriptional regulator
BUN12_RS20595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUN12_RS20595	COG1263	PTS System
BUN12_RS20600	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN12_RS20605	COG1132	(ABC) transporter
BUN12_RS20610	COG1132	(ABC) transporter
BUN12_RS20615	COG2259	Doxx family
BUN12_RS20620	COG2514	catechol 2,3-dioxygenase activity
BUN12_RS20630	COG1695	Transcriptional regulator
BUN12_RS20635	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUN12_RS20640	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BUN12_RS20645	COG2732	(Barnase) inhibitor
BUN12_RS20650	COG2318	DinB family
BUN12_RS20655	COG2814	Major facilitator Superfamily
BUN12_RS20660	COG1846	Transcriptional regulator
BUN12_RS20665	COG0392	lysyltransferase activity
BUN12_RS20665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BUN12_RS20670	COG0384	phenazine biosynthesis protein PhzF
BUN12_RS20675	COG0778	Nitroreductase
BUN12_RS20690	COG1090	epimerase
BUN12_RS20715	COG3591	Belongs to the peptidase S1B family
BUN12_RS20730	COG3103	Sh3 type 3 domain protein
BUN12_RS20755	COG1988	membrane-bound metal-dependent
BUN12_RS20760	COG0582	viral genome integration into host DNA
BUN12_RS20795	COG3645	SOS response
BUN12_RS20795	COG3646	Phage regulatory protein