locus-tag	class	description
KSO_RS00010	COG0706	membrane insertase activity
KSO_RS00015	COG1847	R3H domain protein
KSO_RS00040	COG1192	Involved in chromosome partitioning
KSO_RS00045	COG1475	DNA binding
KSO_RS00060	COG3949	Membrane
KSO_RS00065	COG4481	Protein conserved in bacteria
KSO_RS00070	COG0243	molybdopterin cofactor binding
KSO_RS00075	COG0012	GTP binding
KSO_RS00085	COG0629	single-stranded DNA binding
KSO_RS00095	COG2169	Transcriptional regulator
KSO_RS00100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KSO_RS00105	COG0708	Exodeoxyribonuclease III
KSO_RS00110	COG1609	Transcriptional regulator
KSO_RS00115	COG0346	lactoylglutathione lyase activity
KSO_RS00120	COG0477	Major facilitator Superfamily
KSO_RS00120	COG2814	Major facilitator Superfamily
KSO_RS00125	COG1266	CAAX protease self-immunity
KSO_RS00130	COG1331	Highly conserved protein containing a thioredoxin domain
KSO_RS00140	COG1396	sequence-specific DNA binding
KSO_RS00145	COG1959	2 iron, 2 sulfur cluster binding
KSO_RS00155	COG0697	spore germination
KSO_RS00160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSO_RS00165	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS00170	COG0583	DNA-binding transcription factor activity
KSO_RS00195	COG1846	Transcriptional regulator
KSO_RS00200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS00205	COG1846	Transcriptional regulator
KSO_RS00210	COG0778	Nitroreductase
KSO_RS00220	COG2211	Major facilitator Superfamily
KSO_RS00225	COG2318	DinB family
KSO_RS00230	COG1802	Transcriptional regulator
KSO_RS00235	COG1621	beta-fructofuranosidase activity
KSO_RS00240	COG1621	beta-fructofuranosidase activity
KSO_RS00245	COG0697	spore germination
KSO_RS00255	COG1733	regulation of RNA biosynthetic process
KSO_RS00260	COG5577	PFAM Coat F domain
KSO_RS00270	COG4241	membrane
KSO_RS00275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KSO_RS00285	COG0515	serine threonine protein kinase
KSO_RS00295	COG0438	transferase activity, transferring glycosyl groups
KSO_RS00300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KSO_RS00310	COG0297	glycogen (starch) synthase activity
KSO_RS00315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KSO_RS00330	COG0305	Participates in initiation and elongation during chromosome replication
KSO_RS00335	COG0346	lactoylglutathione lyase activity
KSO_RS00370	COG0745	RESPONSE REGULATOR receiver
KSO_RS00375	COG5002	protein histidine kinase activity
KSO_RS00380	COG4863	YycH protein
KSO_RS00385	COG4853	Protein conserved in bacteria
KSO_RS00390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KSO_RS00395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSO_RS00405	COG5002	protein histidine kinase activity
KSO_RS00405	COG3850	Histidine kinase
KSO_RS00410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KSO_RS00425	COG0488	(ABC) transporter
KSO_RS00435	COG3829	transcription factor binding
KSO_RS00440	COG0640	Transcriptional regulator
KSO_RS00445	COG5658	integral membrane protein
KSO_RS00450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KSO_RS00455	COG0833	amino acid
KSO_RS00460	COG0010	Belongs to the arginase family
KSO_RS00465	COG0457	Tetratricopeptide repeat
KSO_RS00470	COG0456	acetyltransferase
KSO_RS00475	COG0667	Aldo Keto reductase
KSO_RS00480	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KSO_RS00510	COG2801	Transposase and inactivated derivatives
KSO_RS00550	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KSO_RS00555	COG2068	MobA-Related Protein
KSO_RS00570	COG2080	2 iron, 2 sulfur cluster binding
KSO_RS00580	COG1113	amino acid transport
KSO_RS00585	COG3634	alkyl hydroperoxide reductase activity
KSO_RS00590	COG0450	alkyl hydroperoxide reductase
KSO_RS00600	COG1714	RDD family
KSO_RS00605	COG2814	Major facilitator Superfamily
KSO_RS00610	COG0640	Transcriptional regulator
KSO_RS00620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KSO_RS00625	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS00630	COG1309	transcriptional regulator
KSO_RS00635	COG3239	Fatty acid desaturase
KSO_RS00640	COG4585	Histidine kinase
KSO_RS00645	COG2197	response regulator
KSO_RS00650	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS00665	COG2814	Major facilitator Superfamily
KSO_RS00670	COG0667	Aldo Keto reductase
KSO_RS00675	COG1349	DNA-binding transcription factor activity
KSO_RS00705	COG2814	Major facilitator Superfamily
KSO_RS00715	COG1082	Xylose isomerase domain protein TIM barrel
KSO_RS00730	COG0745	RESPONSE REGULATOR receiver
KSO_RS00735	COG2205	protein histidine kinase activity
KSO_RS00740	COG1136	(ABC) transporter
KSO_RS00745	COG0577	efflux transmembrane transporter activity
KSO_RS00750	COG5294	Protein conserved in bacteria
KSO_RS00755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KSO_RS00785	COG0561	phosphatase activity
KSO_RS00790	COG2390	Transcriptional regulator
KSO_RS00800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KSO_RS00805	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KSO_RS00810	COG0833	amino acid
KSO_RS00815	COG0010	Belongs to the arginase family
KSO_RS00840	COG3507	Belongs to the glycosyl hydrolase 43 family
KSO_RS00845	COG0494	nUDIX hydrolase
KSO_RS00855	COG0589	response to stress
KSO_RS00860	COG0697	spore germination
KSO_RS00935	COG0513	Belongs to the DEAD box helicase family
KSO_RS00940	COG2270	Major facilitator Superfamily
KSO_RS00950	COG2273	Hydrolase Family 16
KSO_RS00955	COG2851	Citrate transporter
KSO_RS00960	COG0753	catalase activity
KSO_RS00960	COG0693	protein deglycase activity
KSO_RS00975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KSO_RS00980	COG0500	methyltransferase
KSO_RS00985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KSO_RS00990	COG4894	glucomannan catabolic process
KSO_RS01000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KSO_RS01010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS01015	COG2508	Transcriptional regulator
KSO_RS01020	COG3842	ATPase activity
KSO_RS01025	COG0726	polysaccharide deacetylase
KSO_RS01030	COG3493	citrate carrier protein
KSO_RS01035	COG1271	oxidase subunit
KSO_RS01040	COG1294	oxidase, subunit
KSO_RS01045	COG4988	ABC transporter
KSO_RS01050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KSO_RS01055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KSO_RS01060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KSO_RS01065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KSO_RS01070	COG0753	catalase activity
KSO_RS01080	COG1482	cell wall glycoprotein biosynthetic process
KSO_RS01085	COG1940	carbohydrate kinase activity
KSO_RS01090	COG2723	6-phospho-beta-galactosidase activity
KSO_RS01095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS01100	COG1447	Phosphotransferase system cellobiose-specific component IIA
KSO_RS01105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS01110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KSO_RS01115	COG0640	Transcriptional regulator
KSO_RS01125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS01130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS01140	COG3711	transcriptional antiterminator
KSO_RS01140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS01145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS01150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS01155	COG1447	Phosphotransferase system cellobiose-specific component IIA
KSO_RS01160	COG1486	melibiose metabolic process
KSO_RS01165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KSO_RS01170	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KSO_RS01180	COG1696	Membrane protein involved in D-alanine export
KSO_RS01195	COG1575	Belongs to the MenA family. Type 1 subfamily
KSO_RS01200	COG2357	RelA SpoT domain protein
KSO_RS01205	COG1442	glycosyl transferase family 8
KSO_RS01210	COG1404	Belongs to the peptidase S8 family
KSO_RS01215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS01220	COG0346	lactoylglutathione lyase activity
KSO_RS01225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KSO_RS01230	COG0789	Transcriptional regulator
KSO_RS01235	COG4895	conserved protein (DUF2196)
KSO_RS01240	COG1346	cytolysis
KSO_RS01250	COG0583	DNA-binding transcription factor activity
KSO_RS01265	COG2837	iron assimilation
KSO_RS01270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KSO_RS01290	COG1309	transcriptional regulator
KSO_RS01295	COG2246	polysaccharide biosynthetic process
KSO_RS01300	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KSO_RS01305	COG2261	transglycosylase associated protein
KSO_RS01310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KSO_RS01315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KSO_RS01335	COG0454	-acetyltransferase
KSO_RS01340	COG0772	Belongs to the SEDS family
KSO_RS01345	COG0778	Nitroreductase
KSO_RS01350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS01355	COG1404	Belongs to the peptidase S8 family
KSO_RS01365	COG3711	transcriptional antiterminator
KSO_RS01370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS01370	COG1263	PTS System
KSO_RS01375	COG1621	beta-fructofuranosidase activity
KSO_RS01385	COG0351	phosphomethylpyrimidine kinase
KSO_RS01390	COG1695	Transcriptional regulator
KSO_RS01405	COG1216	Glycosyl transferase, family 2
KSO_RS01420	COG2233	PERMEase
KSO_RS01425	COG2363	Small membrane protein
KSO_RS01435	COG0463	Glycosyl transferase, family 2
KSO_RS01440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KSO_RS01445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KSO_RS01450	COG0456	acetyltransferase
KSO_RS01455	COG2089	acid synthase
KSO_RS01460	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KSO_RS01465	COG3980	spore coat polysaccharide biosynthesis protein
KSO_RS01470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KSO_RS01475	COG1088	dTDP-glucose 4,6-dehydratase activity
KSO_RS01480	COG1091	dTDP-4-dehydrorhamnose reductase activity
KSO_RS01485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KSO_RS01495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KSO_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS01505	COG4187	Peptidase family M20/M25/M40
KSO_RS01510	COG0833	amino acid
KSO_RS01515	COG2814	Major facilitator Superfamily
KSO_RS01520	COG2814	Major facilitator Superfamily
KSO_RS01550	COG0436	Aminotransferase
KSO_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS01565	COG0280	phosphate acetyltransferase
KSO_RS01570	COG2855	membrane
KSO_RS01575	COG0583	DNA-binding transcription factor activity
KSO_RS01590	COG1695	Transcriptional regulator
KSO_RS01605	COG1078	dGTPase activity
KSO_RS01610	COG3465	dGTPase activity
KSO_RS01615	COG0531	amino acid
KSO_RS01625	COG1846	Transcriptional regulator
KSO_RS01630	COG1942	4-Oxalocrotonate Tautomerase
KSO_RS01635	COG1994	Peptidase M50
KSO_RS01650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KSO_RS01655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KSO_RS01660	COG0010	Belongs to the arginase family
KSO_RS01700	COG0457	Tetratricopeptide repeat
KSO_RS01705	COG4506	Protein conserved in bacteria
KSO_RS01715	COG2223	nitrite transmembrane transporter activity
KSO_RS01720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KSO_RS01730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KSO_RS01735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KSO_RS01740	COG1140	nitrate reductase beta subunit
KSO_RS01745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KSO_RS01750	COG2181	nitrate reductase activity
KSO_RS01760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KSO_RS01765	COG1132	(ABC) transporter
KSO_RS01780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KSO_RS01785	COG2181	nitrate reductase activity
KSO_RS01785	COG0247	lactate metabolic process
KSO_RS01800	COG4821	SIS domain
KSO_RS01805	COG2204	response regulator
KSO_RS01810	COG0191	fructose-bisphosphate aldolase activity
KSO_RS01820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KSO_RS01825	COG1494	fructose-1,6-bisphosphatase
KSO_RS01830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KSO_RS01845	COG0281	malic enzyme
KSO_RS01850	COG0679	Auxin Efflux Carrier
KSO_RS01855	COG0789	Transcriptional regulator
KSO_RS01860	COG0346	lactoylglutathione lyase activity
KSO_RS01865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KSO_RS01870	COG2890	protein-(glutamine-N5) methyltransferase activity
KSO_RS01890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KSO_RS01895	COG0009	L-threonylcarbamoyladenylate synthase
KSO_RS01905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KSO_RS01910	COG0698	ribose 5-phosphate isomerase
KSO_RS01980	COG4836	Membrane
KSO_RS01990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KSO_RS01995	COG2385	sporulation resulting in formation of a cellular spore
KSO_RS02000	COG2304	oxidoreductase activity
KSO_RS02005	COG2304	oxidoreductase activity
KSO_RS02010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KSO_RS02020	COG0457	Tetratricopeptide repeat
KSO_RS02025	COG1994	Peptidase M50
KSO_RS02030	COG3237	CsbD-like
KSO_RS02035	COG0831	urea catabolic process
KSO_RS02050	COG1959	2 iron, 2 sulfur cluster binding
KSO_RS02060	COG0726	polysaccharide deacetylase
KSO_RS02070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KSO_RS02085	COG1247	-acetyltransferase
KSO_RS02090	COG0739	heme binding
KSO_RS02100	COG0671	phosphoesterase, PA-phosphatase related
KSO_RS02105	COG0772	Belongs to the SEDS family
KSO_RS02110	COG0347	Belongs to the P(II) protein family
KSO_RS02115	COG0004	ammonium transporteR
KSO_RS02120	COG1335	isochorismatase
KSO_RS02125	COG0477	Major facilitator Superfamily
KSO_RS02130	COG1953	Uracil, thiamine, allantoin
KSO_RS02135	COG2814	Major facilitator Superfamily
KSO_RS02140	COG1846	Transcriptional regulator
KSO_RS02145	COG1609	Transcriptional regulator
KSO_RS02150	COG1077	Cell shape determining protein MreB Mrl
KSO_RS02155	COG4786	Flagellar basal body rod
KSO_RS02160	COG4786	Flagellar basal body rod
KSO_RS02165	COG0457	Tetratricopeptide repeat
KSO_RS02190	COG0629	single-stranded DNA binding
KSO_RS02195	COG1349	DNA-binding transcription factor activity
KSO_RS02200	COG0561	phosphatase activity
KSO_RS02205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KSO_RS02210	COG4715	Zinc finger, swim domain protein
KSO_RS02215	COG3944	biosynthesis protein
KSO_RS02220	COG0489	protein tyrosine kinase activity
KSO_RS02225	COG4464	protein tyrosine phosphatase activity
KSO_RS02230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KSO_RS02235	COG3878	Protein conserved in bacteria
KSO_RS02250	COG5444	nuclease activity
KSO_RS02300	COG0583	DNA-binding transcription factor activity
KSO_RS02305	COG0655	NAD(P)H dehydrogenase (quinone) activity
KSO_RS02315	COG2059	Chromate
KSO_RS02320	COG2059	Chromate
KSO_RS02325	COG1522	sequence-specific DNA binding
KSO_RS02330	COG0405	Gamma-glutamyltransferase
KSO_RS02340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSO_RS02350	COG5337	Spore coat protein CotH
KSO_RS02365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KSO_RS02370	COG0583	DNA-binding transcription factor activity
KSO_RS02375	COG0028	Belongs to the TPP enzyme family
KSO_RS02380	COG3527	Alpha-acetolactate decarboxylase
KSO_RS02385	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSO_RS02390	COG3103	Sh3 type 3 domain protein
KSO_RS02395	COG1879	ABC-type sugar transport system periplasmic component
KSO_RS02400	COG1172	Belongs to the binding-protein-dependent transport system permease family
KSO_RS02405	COG1129	ABC transporter
KSO_RS02415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KSO_RS02420	COG1609	Transcriptional regulator
KSO_RS02430	COG0814	amino acid
KSO_RS02435	COG0697	spore germination
KSO_RS02440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KSO_RS02450	COG2843	Capsule synthesis protein
KSO_RS02455	COG0791	NLP P60 protein
KSO_RS02460	COG2433	Pfam Transposase IS66
KSO_RS02465	COG0561	phosphatase activity
KSO_RS02470	COG1316	TRANSCRIPTIONal
KSO_RS02475	COG2814	Major facilitator Superfamily
KSO_RS02480	COG1215	transferase activity, transferring glycosyl groups
KSO_RS02490	COG0814	amino acid
KSO_RS02495	COG0697	spore germination
KSO_RS02500	COG1482	cell wall glycoprotein biosynthetic process
KSO_RS02505	COG4193	domain, Protein
KSO_RS02510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KSO_RS02515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KSO_RS02520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KSO_RS02530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KSO_RS02535	COG1682	transport, permease protein
KSO_RS02540	COG1134	teichoic acid transport
KSO_RS02545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KSO_RS02550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KSO_RS02555	COG1316	TRANSCRIPTIONal
KSO_RS02565	COG2385	sporulation resulting in formation of a cellular spore
KSO_RS02565	COG2247	cell wall binding repeat
KSO_RS02570	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS02570	COG2247	cell wall binding repeat
KSO_RS02580	COG2244	polysaccharide biosynthetic process
KSO_RS02585	COG0438	transferase activity, transferring glycosyl groups
KSO_RS02585	COG0297	glycogen (starch) synthase activity
KSO_RS02590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KSO_RS02595	COG3307	-O-antigen
KSO_RS02600	COG3206	protein involved in exopolysaccharide biosynthesis
KSO_RS02605	COG1215	transferase activity, transferring glycosyl groups
KSO_RS02610	COG0438	transferase activity, transferring glycosyl groups
KSO_RS02615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KSO_RS02620	COG1316	TRANSCRIPTIONal
KSO_RS02625	COG1739	Uncharacterized protein family UPF0029
KSO_RS02630	COG4585	Histidine kinase
KSO_RS02635	COG2197	response regulator
KSO_RS02640	COG1307	EDD domain protein, DegV family
KSO_RS02645	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KSO_RS02655	COG1040	competence protein
KSO_RS02665	COG2747	anti-sigma28 factor FlgM
KSO_RS02670	COG3418	PFAM FlgN family protein
KSO_RS02675	COG1256	bacterial-type flagellum assembly
KSO_RS02675	COG4786	Flagellar basal body rod
KSO_RS02680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KSO_RS02700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KSO_RS02705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KSO_RS02710	COG1516	flagellar protein fliS
KSO_RS02725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KSO_RS02735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KSO_RS02740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS02745	COG2010	Cytochrome c
KSO_RS02750	COG2884	Cell division ATP-binding protein ftsE
KSO_RS02755	COG2177	Part of the ABC transporter FtsEX involved in
KSO_RS02760	COG3420	alginic acid biosynthetic process
KSO_RS02765	COG0793	Belongs to the peptidase S41A family
KSO_RS02765	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS02775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSO_RS02800	COG2814	Major facilitator Superfamily
KSO_RS02805	COG1309	transcriptional regulator
KSO_RS02810	COG0574	Belongs to the PEP-utilizing enzyme family
KSO_RS02810	COG3848	Pyruvate phosphate dikinase
KSO_RS02815	COG4897	Protein conserved in bacteria
KSO_RS02825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KSO_RS02840	COG3595	metallopeptidase activity
KSO_RS02845	COG1983	PspC domain protein
KSO_RS02850	COG1950	PFAM Membrane protein of
KSO_RS02855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KSO_RS02860	COG1309	transcriptional regulator
KSO_RS02865	COG2188	Transcriptional regulator
KSO_RS02875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KSO_RS02895	COG0110	maltose O-acetyltransferase activity
KSO_RS02900	COG4990	cell redox homeostasis
KSO_RS02915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KSO_RS02940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KSO_RS02940	COG0140	phosphoribosyl-ATP diphosphatase activity
KSO_RS02945	COG1132	(ABC) transporter
KSO_RS02955	COG0745	RESPONSE REGULATOR receiver
KSO_RS02960	COG5002	protein histidine kinase activity
KSO_RS02965	COG0457	Tetratricopeptide repeat
KSO_RS02970	COG3883	PFAM NLP P60 protein
KSO_RS02970	COG0791	NLP P60 protein
KSO_RS02975	COG0492	ferredoxin-NADP+ reductase activity
KSO_RS02980	COG1051	belongs to the nudix hydrolase family
KSO_RS02990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KSO_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS03005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KSO_RS03010	COG4290	ribonuclease
KSO_RS03015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KSO_RS03020	COG0288	reversible hydration of carbon dioxide
KSO_RS03025	COG0659	secondary active sulfate transmembrane transporter activity
KSO_RS03030	COG1694	Mazg nucleotide pyrophosphohydrolase
KSO_RS03035	COG1611	Belongs to the LOG family
KSO_RS03040	COG0477	Major facilitator Superfamily
KSO_RS03040	COG2814	Major facilitator Superfamily
KSO_RS03045	COG2828	Protein conserved in bacteria
KSO_RS03050	COG0583	DNA-binding transcription factor activity
KSO_RS03060	COG1609	Transcriptional regulator
KSO_RS03065	COG2223	nitrite transmembrane transporter activity
KSO_RS03120	COG3479	Phenolic acid decarboxylase
KSO_RS03125	COG0456	acetyltransferase
KSO_RS03130	COG2364	Membrane
KSO_RS03135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KSO_RS03145	COG2272	Belongs to the type-B carboxylesterase lipase family
KSO_RS03150	COG1396	sequence-specific DNA binding
KSO_RS03155	COG3944	biosynthesis protein
KSO_RS03160	COG0489	protein tyrosine kinase activity
KSO_RS03165	COG1086	Polysaccharide biosynthesis protein
KSO_RS03170	COG0438	transferase activity, transferring glycosyl groups
KSO_RS03175	COG1215	transferase activity, transferring glycosyl groups
KSO_RS03180	COG0438	transferase activity, transferring glycosyl groups
KSO_RS03190	COG1216	Glycosyl transferase, family 2
KSO_RS03195	COG5039	Polysaccharide pyruvyl transferase
KSO_RS03200	COG1216	Glycosyl transferase, family 2
KSO_RS03205	COG2244	polysaccharide biosynthetic process
KSO_RS03210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KSO_RS03215	COG0110	maltose O-acetyltransferase activity
KSO_RS03220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KSO_RS03225	COG5039	Polysaccharide pyruvyl transferase
KSO_RS03235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KSO_RS03240	COG1620	l-lactate permease
KSO_RS03245	COG2186	Transcriptional regulator
KSO_RS03250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSO_RS03275	COG1070	Carbohydrate kinase
KSO_RS03280	COG1737	Transcriptional regulator
KSO_RS03285	COG0561	phosphatase activity
KSO_RS03295	COG1609	Transcriptional regulator
KSO_RS03305	COG1113	amino acid transport
KSO_RS03310	COG0697	spore germination
KSO_RS03315	COG0583	DNA-binding transcription factor activity
KSO_RS03325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS03330	COG1609	Transcriptional regulator
KSO_RS03335	COG2814	Major facilitator Superfamily
KSO_RS03340	COG2390	Transcriptional regulator
KSO_RS03345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KSO_RS03355	COG0126	phosphoglycerate kinase activity
KSO_RS03375	COG2234	aminopeptidase activity
KSO_RS03385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KSO_RS03390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS03395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KSO_RS03410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KSO_RS03425	COG0456	acetyltransferase
KSO_RS03430	COG4640	response to antibiotic
KSO_RS03435	COG3064	Membrane
KSO_RS03450	COG1510	regulation of RNA biosynthetic process
KSO_RS03455	COG0517	IMP dehydrogenase activity
KSO_RS03455	COG1125	glycine betaine transport
KSO_RS03460	COG1174	glycine betaine transport
KSO_RS03465	COG1732	Glycine betaine
KSO_RS03470	COG1174	glycine betaine transport
KSO_RS03475	COG1510	regulation of RNA biosynthetic process
KSO_RS03480	COG0517	IMP dehydrogenase activity
KSO_RS03480	COG1125	glycine betaine transport
KSO_RS03485	COG1174	glycine betaine transport
KSO_RS03490	COG1732	Glycine betaine
KSO_RS03495	COG1174	glycine betaine transport
KSO_RS03500	COG1131	(ABC) transporter
KSO_RS03525	COG1733	regulation of RNA biosynthetic process
KSO_RS03530	COG1396	sequence-specific DNA binding
KSO_RS03535	COG1396	sequence-specific DNA binding
KSO_RS03540	COG1476	TRANSCRIPTIONal
KSO_RS03545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KSO_RS03550	COG1647	Serine aminopeptidase, S33
KSO_RS03555	COG0557	exoribonuclease II activity
KSO_RS03575	COG2732	(Barnase) inhibitor
KSO_RS03580	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS03585	COG0583	DNA-binding transcription factor activity
KSO_RS03590	COG0454	-acetyltransferase
KSO_RS03595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS03600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS03605	COG0765	amino acid transport
KSO_RS03610	COG0765	amino acid transport
KSO_RS03615	COG1126	abc transporter atp-binding protein
KSO_RS03620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS03625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KSO_RS03630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS03645	COG2814	Major facilitator Superfamily
KSO_RS03660	COG0673	inositol 2-dehydrogenase activity
KSO_RS03665	COG1937	Protein conserved in bacteria
KSO_RS03670	COG2608	mercury ion transmembrane transporter activity
KSO_RS03675	COG2217	Heavy metal translocating P-type atpase
KSO_RS03680	COG2217	Heavy metal translocating P-type atpase
KSO_RS03685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KSO_RS03690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KSO_RS03700	COG2860	membrane
KSO_RS03705	COG3973	AAA domain
KSO_RS03710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KSO_RS03735	COG0656	L-ascorbic acid biosynthetic process
KSO_RS03740	COG0842	Transport permease protein
KSO_RS03750	COG1131	(ABC) transporter
KSO_RS03755	COG3850	Histidine kinase
KSO_RS03760	COG2197	response regulator
KSO_RS03765	COG4149	molybdate abc transporter
KSO_RS03770	COG0725	ABC transporter, periplasmic molybdate-binding protein
KSO_RS03775	COG1910	domain protein
KSO_RS03780	COG1368	sulfuric ester hydrolase activity
KSO_RS03785	COG1988	membrane-bound metal-dependent
KSO_RS03795	COG0531	amino acid
KSO_RS03800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KSO_RS03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KSO_RS03810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS03815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS03820	COG1120	ATPase activity
KSO_RS03830	COG2140	Oxalate decarboxylase
KSO_RS03835	COG1191	sigma factor activity
KSO_RS03845	COG0745	RESPONSE REGULATOR receiver
KSO_RS03850	COG2205	protein histidine kinase activity
KSO_RS03855	COG3386	PFAM SMP-30 Gluconolaconase
KSO_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS03865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KSO_RS03870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS03875	COG1120	ATPase activity
KSO_RS03880	COG2096	Adenosyltransferase
KSO_RS03885	COG2814	Major facilitator Superfamily
KSO_RS03890	COG4758	membrane
KSO_RS03895	COG1842	Phage shock protein A
KSO_RS03900	COG3595	metallopeptidase activity
KSO_RS03905	COG4758	membrane
KSO_RS03910	COG4585	Histidine kinase
KSO_RS03915	COG2197	response regulator
KSO_RS03925	COG0814	amino acid
KSO_RS03930	COG0697	spore germination
KSO_RS03940	COG0114	fumarate hydratase activity
KSO_RS03945	COG1309	transcriptional regulator
KSO_RS03950	COG2770	Histidine kinase
KSO_RS03950	COG2205	protein histidine kinase activity
KSO_RS03955	COG0745	RESPONSE REGULATOR receiver
KSO_RS03960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSO_RS03965	COG0783	Belongs to the Dps family
KSO_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS03985	COG1120	ATPase activity
KSO_RS04005	COG0583	DNA-binding transcription factor activity
KSO_RS04010	COG0477	Major facilitator Superfamily
KSO_RS04015	COG1846	Transcriptional regulator
KSO_RS04020	COG5577	PFAM Coat F domain
KSO_RS04040	COG1024	Enoyl-CoA hydratase
KSO_RS04040	COG1250	3-hydroxyacyl-CoA dehydrogenase
KSO_RS04045	COG0183	Belongs to the thiolase family
KSO_RS04050	COG1960	acyl-CoA dehydrogenase activity
KSO_RS04055	COG1393	Belongs to the ArsC family
KSO_RS04070	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KSO_RS04075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS04085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KSO_RS04090	COG2011	ABC-type metal ion transport system permease component
KSO_RS04095	COG1464	Belongs to the NlpA lipoprotein family
KSO_RS04100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KSO_RS04105	COG0396	ATPase activity
KSO_RS04110	COG0719	Fe-S assembly protein
KSO_RS04115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KSO_RS04120	COG0822	iron-sulfur transferase activity
KSO_RS04125	COG0719	Fe-S assembly protein
KSO_RS04130	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS04135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSO_RS04140	COG0322	excinuclease ABC activity
KSO_RS04150	COG0789	Transcriptional regulator
KSO_RS04155	COG2222	sugar isomerase
KSO_RS04160	COG1653	transport
KSO_RS04165	COG1175	transmembrane transport
KSO_RS04170	COG0395	ABC-type sugar transport system, permease component
KSO_RS04175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KSO_RS04180	COG2188	Transcriptional regulator
KSO_RS04185	COG3842	ATPase activity
KSO_RS04190	COG2356	endonuclease I
KSO_RS04195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KSO_RS04200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KSO_RS04205	COG2814	Major facilitator Superfamily
KSO_RS04215	COG2508	Transcriptional regulator
KSO_RS04230	COG1801	Protein of unknown function DUF72
KSO_RS04235	COG0730	response to heat
KSO_RS04240	COG0737	Belongs to the 5'-nucleotidase family
KSO_RS04250	COG0739	heme binding
KSO_RS04260	COG4470	Protein conserved in bacteria
KSO_RS04265	COG2445	Protein of unknown function DUF86
KSO_RS04270	COG0647	UMP catabolic process
KSO_RS04275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KSO_RS04280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KSO_RS04285	COG0460	homoserine dehydrogenase
KSO_RS04290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KSO_RS04300	COG0823	Involved in the tonB-independent uptake of proteins
KSO_RS04300	COG1506	peptidase
KSO_RS04300	COG4946	Tricorn protease homolog
KSO_RS04305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KSO_RS04310	COG4837	Protein of unknown function (DUF1462)
KSO_RS04315	COG1252	NADH dehydrogenase
KSO_RS04325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KSO_RS04335	COG0316	Belongs to the HesB IscA family
KSO_RS04340	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KSO_RS04365	COG1131	(ABC) transporter
KSO_RS04395	COG1252	NADH dehydrogenase
KSO_RS04405	COG3584	3D domain protein
KSO_RS04410	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KSO_RS04420	COG2056	Na+-H+ antiporter family
KSO_RS04425	COG1268	BioY protein
KSO_RS04430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KSO_RS04435	COG2819	hydrolase of the alpha beta superfamily
KSO_RS04440	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS04445	COG1169	isochorismate synthase
KSO_RS04450	COG1021	2,3-dihydroxybenzoate-AMP ligase
KSO_RS04455	COG1535	isochorismatase
KSO_RS04455	COG3433	isochorismatase activity
KSO_RS04460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS04465	COG3251	PFAM MbtH domain protein
KSO_RS04470	COG5634	Uncharacterized conserved protein (DUF2278)
KSO_RS04475	COG0686	Belongs to the AlaDH PNT family
KSO_RS04480	COG2508	Transcriptional regulator
KSO_RS04480	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KSO_RS04485	COG4842	Belongs to the WXG100 family
KSO_RS04490	COG5417	Belongs to the EsaB family
KSO_RS04495	COG4499	WXG100 protein secretion system (Wss), protein YukC
KSO_RS04500	COG1674	ftsk spoiiie
KSO_RS04500	COG0433	COG0433 Predicted ATPase
KSO_RS04505	COG1511	domain protein
KSO_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS04520	COG1418	mRNA catabolic process
KSO_RS04530	COG0628	permease
KSO_RS04545	COG5506	Protein of unknown function (DUF1694)
KSO_RS04550	COG1335	isochorismatase
KSO_RS04555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KSO_RS04560	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KSO_RS04575	COG0142	geranyltranstransferase activity
KSO_RS04585	COG4585	Histidine kinase
KSO_RS04590	COG2197	response regulator
KSO_RS04595	COG2050	protein possibly involved in aromatic compounds catabolism
KSO_RS04600	COG1320	monovalent cation:proton antiporter activity
KSO_RS04605	COG2212	antiporter activity
KSO_RS04610	COG1863	multisubunit Na H antiporter MnhE subunit
KSO_RS04615	COG0651	ATP synthesis coupled electron transport
KSO_RS04620	COG1006	Multisubunit Na H antiporter MnhC subunit
KSO_RS04625	COG2111	Na H antiporter
KSO_RS04630	COG2111	Na H antiporter
KSO_RS04630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KSO_RS04640	COG1079	Belongs to the binding-protein-dependent transport system permease family
KSO_RS04645	COG4603	Belongs to the binding-protein-dependent transport system permease family
KSO_RS04650	COG3845	ABC transporter
KSO_RS04655	COG1744	ABC transporter substrate-binding protein PnrA-like
KSO_RS04660	COG4565	transcriptional regulatory protein
KSO_RS04665	COG3290	protein histidine kinase activity
KSO_RS04675	COG3011	Protein conserved in bacteria
KSO_RS04680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KSO_RS04685	COG2814	Major facilitator Superfamily
KSO_RS04690	COG5018	Exonuclease
KSO_RS04700	COG2205	protein histidine kinase activity
KSO_RS04705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KSO_RS04715	COG2267	carboxylic ester hydrolase activity
KSO_RS04720	COG1522	sequence-specific DNA binding
KSO_RS04725	COG0436	Aminotransferase
KSO_RS04730	COG1098	S1 RNA binding domain
KSO_RS04735	COG2155	Conserved Protein
KSO_RS04740	COG1979	alcohol dehydrogenase
KSO_RS04745	COG1979	alcohol dehydrogenase
KSO_RS04750	COG1335	isochorismatase
KSO_RS04775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KSO_RS04790	COG2738	Putative neutral zinc metallopeptidase
KSO_RS04795	COG1253	flavin adenine dinucleotide binding
KSO_RS04800	COG0366	Alpha amylase catalytic
KSO_RS04805	COG0432	Pfam Uncharacterised protein family UPF0047
KSO_RS04810	COG2070	2-Nitropropane dioxygenase
KSO_RS04825	COG0840	transmembrane signaling receptor activity
KSO_RS04830	COG0840	transmembrane signaling receptor activity
KSO_RS04835	COG0840	transmembrane signaling receptor activity
KSO_RS04840	COG0840	transmembrane signaling receptor activity
KSO_RS04845	COG0693	protein deglycase activity
KSO_RS04850	COG0673	inositol 2-dehydrogenase activity
KSO_RS04855	COG0628	permease
KSO_RS04880	COG0457	Tetratricopeptide repeat
KSO_RS04900	COG1017	nitric oxide dioxygenase activity
KSO_RS04900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSO_RS04905	COG1705	Flagellar rod assembly protein muramidase FlgJ
KSO_RS04910	COG0569	domain protein
KSO_RS04920	COG1510	regulation of RNA biosynthetic process
KSO_RS04925	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS04930	COG1454	alcohol dehydrogenase
KSO_RS04940	COG2318	DinB family
KSO_RS04945	COG1585	Membrane protein implicated in regulation of membrane protease activity
KSO_RS04950	COG2268	Band 7 protein
KSO_RS04955	COG3859	Proton-coupled thiamine transporter YuaJ
KSO_RS05080	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KSO_RS05085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KSO_RS05090	COG1169	isochorismate synthase
KSO_RS05100	COG0596	Alpha beta hydrolase
KSO_RS05105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KSO_RS05115	COG4948	Mandelate Racemase Muconate Lactonizing
KSO_RS05125	COG1294	oxidase, subunit
KSO_RS05130	COG1271	oxidase subunit
KSO_RS05140	COG0288	reversible hydration of carbon dioxide
KSO_RS05165	COG0783	Belongs to the Dps family
KSO_RS05170	COG4824	toxin secretion phage lysis holin
KSO_RS05175	COG0494	nUDIX hydrolase
KSO_RS05180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSO_RS05185	COG1116	anion transmembrane transporter activity
KSO_RS05190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSO_RS05195	COG1506	peptidase
KSO_RS05215	COG0367	asparagine synthase
KSO_RS05220	COG1113	amino acid transport
KSO_RS05225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KSO_RS05230	COG2267	carboxylic ester hydrolase activity
KSO_RS05240	COG0584	glycerophosphoryl diester phosphodiesterase
KSO_RS05250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KSO_RS05255	COG1242	4 iron, 4 sulfur cluster binding
KSO_RS05265	COG1725	Transcriptional regulator
KSO_RS05270	COG1131	(ABC) transporter
KSO_RS05290	COG1136	(ABC) transporter
KSO_RS05295	COG0577	efflux transmembrane transporter activity
KSO_RS05300	COG0745	RESPONSE REGULATOR receiver
KSO_RS05305	COG2205	protein histidine kinase activity
KSO_RS05310	COG1136	(ABC) transporter
KSO_RS05315	COG0577	efflux transmembrane transporter activity
KSO_RS05320	COG5522	Integral membrane protein (intg_mem_TP0381)
KSO_RS05325	COG2814	Major facilitator Superfamily
KSO_RS05330	COG2202	Pas domain
KSO_RS05330	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS05345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KSO_RS05355	COG1486	melibiose metabolic process
KSO_RS05360	COG0395	ABC-type sugar transport system, permease component
KSO_RS05365	COG1175	transmembrane transport
KSO_RS05370	COG1653	transport
KSO_RS05375	COG1609	Transcriptional regulator
KSO_RS05385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSO_RS05390	COG2081	HI0933 family
KSO_RS05395	COG2244	polysaccharide biosynthetic process
KSO_RS05400	COG1187	pseudouridine synthase activity
KSO_RS05405	COG1349	DNA-binding transcription factor activity
KSO_RS05410	COG1131	(ABC) transporter
KSO_RS05415	COG4473	ABC transporter
KSO_RS05420	COG2252	PERMEase
KSO_RS05425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KSO_RS05430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KSO_RS05435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KSO_RS05445	COG1597	lipid kinase activity
KSO_RS05450	COG0510	thiamine kinase activity
KSO_RS05465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS05470	COG0281	malic enzyme
KSO_RS05475	COG5584	Small secreted protein
KSO_RS05480	COG1363	Peptidase, m42
KSO_RS05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS05500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSO_RS05505	COG1674	ftsk spoiiie
KSO_RS05515	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KSO_RS05520	COG4980	gas vesicle protein
KSO_RS05525	COG3118	belongs to the thioredoxin family
KSO_RS05530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KSO_RS05530	COG1605	Chorismate mutase
KSO_RS05535	COG1609	Transcriptional regulator
KSO_RS05540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KSO_RS05545	COG1360	Flagellar Motor Protein
KSO_RS05550	COG0123	including yeast histone deacetylase and acetoin utilization protein
KSO_RS05555	COG0517	IMP dehydrogenase activity
KSO_RS05560	COG0454	-acetyltransferase
KSO_RS05565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KSO_RS05585	COG1378	Sugar-specific transcriptional regulator TrmB
KSO_RS05590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KSO_RS05605	COG0693	protein deglycase activity
KSO_RS05615	COG1017	nitric oxide dioxygenase activity
KSO_RS05615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSO_RS05620	COG4282	regulation of fungal-type cell wall biogenesis
KSO_RS05625	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS05635	COG2199	diguanylate cyclase activity
KSO_RS05635	COG2203	Gaf domain
KSO_RS05640	COG1956	GAF domain-containing protein
KSO_RS05645	COG1309	transcriptional regulator
KSO_RS05650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KSO_RS05660	COG1114	Component of the transport system for branched-chain amino acids
KSO_RS05665	COG1104	cysteine desulfurase activity
KSO_RS05680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KSO_RS05685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KSO_RS05690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KSO_RS05695	COG0616	signal peptide processing
KSO_RS05700	COG1714	RDD family
KSO_RS05710	COG3874	Sporulation protein YtfJ
KSO_RS05715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KSO_RS05720	COG0827	DNA restriction-modification system
KSO_RS05730	COG0521	Mo-molybdopterin cofactor biosynthetic process
KSO_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS05755	COG4109	DRTGG domain
KSO_RS05765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KSO_RS05785	COG0587	DNA-directed DNA polymerase activity
KSO_RS05790	COG0281	malic enzyme
KSO_RS05815	COG0469	pyruvate kinase activity
KSO_RS05820	COG3030	protein affecting phage T7 exclusion by the F plasmid
KSO_RS05825	COG0628	permease
KSO_RS05840	COG0372	Belongs to the citrate synthase family
KSO_RS05845	COG0538	isocitrate dehydrogenase activity
KSO_RS05855	COG0745	RESPONSE REGULATOR receiver
KSO_RS05860	COG5002	protein histidine kinase activity
KSO_RS05865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KSO_RS05865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KSO_RS05870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KSO_RS05875	COG1971	Probably functions as a manganese efflux pump
KSO_RS05880	COG0237	dephospho-CoA kinase activity
KSO_RS05885	COG0656	L-ascorbic acid biosynthetic process
KSO_RS05890	COG2814	Major facilitator Superfamily
KSO_RS05895	COG1733	regulation of RNA biosynthetic process
KSO_RS05900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KSO_RS05915	COG3611	Membrane attachment protein
KSO_RS05920	COG1484	DNA-dependent DNA replication
KSO_RS05925	COG0398	Pfam SNARE associated Golgi protein
KSO_RS05940	COG1011	Hydrolase
KSO_RS05945	COG3275	phosphorelay sensor kinase activity
KSO_RS05950	COG3279	Response regulator of the LytR AlgR family
KSO_RS05955	COG1380	Effector of murein hydrolase LrgA
KSO_RS05960	COG1346	cytolysis
KSO_RS05965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KSO_RS05975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KSO_RS05990	COG1363	Peptidase, m42
KSO_RS05995	COG3507	Belongs to the glycosyl hydrolase 43 family
KSO_RS06000	COG2160	L-arabinose isomerase activity
KSO_RS06005	COG1069	ribulokinase activity
KSO_RS06010	COG0235	Class ii aldolase
KSO_RS06015	COG0647	UMP catabolic process
KSO_RS06025	COG1653	transport
KSO_RS06030	COG1175	transmembrane transport
KSO_RS06035	COG0395	ABC-type sugar transport system, permease component
KSO_RS06040	COG3534	alpha-L-arabinofuranosidase
KSO_RS06045	COG1966	Carbon starvation protein
KSO_RS06050	COG0247	lactate metabolic process
KSO_RS06055	COG0277	FAD linked oxidase domain protein
KSO_RS06060	COG3835	regulator
KSO_RS06070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KSO_RS06075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KSO_RS06080	COG0072	phenylalanine-tRNA ligase activity
KSO_RS06080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSO_RS06095	COG1286	toxin biosynthetic process
KSO_RS06100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KSO_RS06100	COG1796	DNA polymerase
KSO_RS06110	COG3766	membrane
KSO_RS06120	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS06125	COG1309	transcriptional regulator
KSO_RS06130	COG1024	Enoyl-CoA hydratase
KSO_RS06135	COG2086	electron transfer activity
KSO_RS06140	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KSO_RS06145	COG3534	alpha-L-arabinofuranosidase
KSO_RS06150	COG3118	belongs to the thioredoxin family
KSO_RS06160	COG0527	aspartate kinase activity
KSO_RS06165	COG1719	4-vinyl reductase, 4VR
KSO_RS06170	COG2009	succinate dehydrogenase
KSO_RS06175	COG1053	succinate dehydrogenase
KSO_RS06180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KSO_RS06185	COG0824	Thioesterase
KSO_RS06190	COG2197	response regulator
KSO_RS06195	COG1846	Transcriptional regulator
KSO_RS06205	COG5401	PFAM Sporulation and spore germination
KSO_RS06215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KSO_RS06220	COG0622	Phosphoesterase
KSO_RS06245	COG0028	Belongs to the TPP enzyme family
KSO_RS06250	COG0440	acetolactate synthase activity
KSO_RS06265	COG0473	3-isopropylmalate dehydrogenase activity
KSO_RS06280	COG1477	protein flavinylation
KSO_RS06280	COG0457	Tetratricopeptide repeat
KSO_RS06295	COG0470	DNA polymerase III
KSO_RS06295	COG1067	ATP-dependent peptidase activity
KSO_RS06300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KSO_RS06320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KSO_RS06330	COG1587	Uroporphyrinogen-III synthase
KSO_RS06335	COG0113	porphobilinogen synthase activity
KSO_RS06345	COG1388	LysM domain
KSO_RS06350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KSO_RS06360	COG0525	valine-tRNA ligase activity
KSO_RS06365	COG0285	dihydrofolate synthase activity
KSO_RS06370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KSO_RS06390	COG1077	Cell shape determining protein MreB Mrl
KSO_RS06400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KSO_RS06410	COG2894	cell division
KSO_RS06415	COG0739	heme binding
KSO_RS06420	COG1994	Peptidase M50
KSO_RS06430	COG2868	ribosomal protein
KSO_RS06435	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KSO_RS06440	COG3290	protein histidine kinase activity
KSO_RS06455	COG0077	Prephenate dehydratase
KSO_RS06460	COG1827	regulation of RNA biosynthetic process
KSO_RS06465	COG1104	cysteine desulfurase activity
KSO_RS06470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KSO_RS06475	COG0157	Belongs to the NadC ModD family
KSO_RS06485	COG1388	LysM domain
KSO_RS06530	COG1862	Preprotein translocase
KSO_RS06540	COG2323	membrane
KSO_RS06545	COG2244	polysaccharide biosynthetic process
KSO_RS06555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KSO_RS06555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KSO_RS06560	COG0490	domain, Protein
KSO_RS06565	COG5416	Lipopolysaccharide assembly protein A domain
KSO_RS06570	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KSO_RS06570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KSO_RS06580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KSO_RS06590	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS06590	COG3103	Sh3 type 3 domain protein
KSO_RS06590	COG4991	sh3 domain protein
KSO_RS06605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KSO_RS06610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KSO_RS06615	COG1959	2 iron, 2 sulfur cluster binding
KSO_RS06620	COG1104	cysteine desulfurase activity
KSO_RS06630	COG0457	Tetratricopeptide repeat
KSO_RS06635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KSO_RS06640	COG3881	PFAM PRC-barrel domain
KSO_RS06650	COG0765	amino acid transport
KSO_RS06655	COG0765	amino acid transport
KSO_RS06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS06665	COG1126	abc transporter atp-binding protein
KSO_RS06670	COG0628	permease
KSO_RS06680	COG4472	Bacterial protein of unknown function (DUF965)
KSO_RS06695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KSO_RS06700	COG4122	O-methyltransferase activity
KSO_RS06705	COG0826	peptidase U32
KSO_RS06710	COG0826	peptidase U32
KSO_RS06820	COG1595	DNA-templated transcription, initiation
KSO_RS06825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KSO_RS06830	COG0582	viral genome integration into host DNA
KSO_RS06920	COG3953	SLT domain
KSO_RS06920	COG5280	Phage tail tape measure protein TP901
KSO_RS06930	COG1705	Flagellar rod assembly protein muramidase FlgJ
KSO_RS06935	COG5434	Belongs to the glycosyl hydrolase 28 family
KSO_RS06955	COG4824	toxin secretion phage lysis holin
KSO_RS06960	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS06960	COG5632	N-Acetylmuramoyl-L-alanine amidase
KSO_RS06985	COG0768	penicillin binding
KSO_RS07010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KSO_RS07015	COG0626	cystathionine gamma-synthase activity
KSO_RS07025	COG2427	Protein of unknown function (DUF1641)
KSO_RS07030	COG3383	formate dehydrogenase (NAD+) activity
KSO_RS07035	COG5609	conserved protein (DUF2294)
KSO_RS07040	COG2116	formate transmembrane transporter activity
KSO_RS07050	COG2226	methyltransferase
KSO_RS07055	COG1309	transcriptional regulator
KSO_RS07060	COG2124	cytochrome p450
KSO_RS07060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KSO_RS07065	COG2814	Major facilitator Superfamily
KSO_RS07070	COG0583	DNA-binding transcription factor activity
KSO_RS07075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KSO_RS07085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS07085	COG3711	transcriptional antiterminator
KSO_RS07090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSO_RS07090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSO_RS07090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS07095	COG1482	cell wall glycoprotein biosynthetic process
KSO_RS07105	COG0561	phosphatase activity
KSO_RS07110	COG0561	phosphatase activity
KSO_RS07120	COG2318	DinB family
KSO_RS07125	COG0456	acetyltransferase
KSO_RS07130	COG2814	Major facilitator Superfamily
KSO_RS07135	COG0563	adenylate kinase activity
KSO_RS07140	COG3708	Transcriptional regulator
KSO_RS07140	COG2207	Transcriptional regulator
KSO_RS07165	COG0398	Pfam SNARE associated Golgi protein
KSO_RS07175	COG2755	lipolytic protein G-D-S-L family
KSO_RS07185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KSO_RS07190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KSO_RS07195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KSO_RS07200	COG1534	Rna-binding protein
KSO_RS07210	COG1713	HD superfamily hydrolase involved in NAD metabolism
KSO_RS07215	COG0799	negative regulation of ribosome biogenesis
KSO_RS07220	COG2226	methyltransferase
KSO_RS07225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KSO_RS07230	COG1555	photosystem II stabilization
KSO_RS07230	COG1596	polysaccharide export
KSO_RS07235	COG2131	deaminase
KSO_RS07240	COG2333	competence protein COMEC
KSO_RS07240	COG0658	competence protein
KSO_RS07245	COG1466	dna polymerase III delta subunit
KSO_RS07260	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS07275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KSO_RS07305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KSO_RS07310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KSO_RS07315	COG1283	sodium-dependent phosphate transmembrane transporter activity
KSO_RS07325	COG1610	YqeY-like protein
KSO_RS07330	COG1030	water channel activity
KSO_RS07335	COG4864	UPF0365 protein
KSO_RS07350	COG0561	phosphatase activity
KSO_RS07355	COG1702	phosphate starvation-inducible protein PhoH
KSO_RS07360	COG1480	7TM receptor with intracellular HD hydrolase
KSO_RS07370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KSO_RS07375	COG0295	cytidine deaminase activity
KSO_RS07380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KSO_RS07395	COG0751	glycine-tRNA ligase activity
KSO_RS07400	COG0517	IMP dehydrogenase activity
KSO_RS07415	COG0358	DNA primase activity
KSO_RS07420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KSO_RS07425	COG2010	Cytochrome c
KSO_RS07430	COG2384	SAM-dependent methyltransferase
KSO_RS07435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KSO_RS07450	COG0513	Belongs to the DEAD box helicase family
KSO_RS07465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS07470	COG0735	belongs to the Fur family
KSO_RS07475	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KSO_RS07480	COG4709	membrane
KSO_RS07490	COG1388	LysM domain
KSO_RS07495	COG5521	maltodextrose utilization protein MalA
KSO_RS07500	COG2839	Protein conserved in bacteria
KSO_RS07505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KSO_RS07510	COG0477	Major facilitator Superfamily
KSO_RS07515	COG0768	penicillin binding
KSO_RS07520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KSO_RS07525	COG0573	inorganic phosphate transmembrane transporter activity
KSO_RS07530	COG0581	inorganic phosphate transmembrane transporter activity
KSO_RS07535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KSO_RS07540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KSO_RS07545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KSO_RS07555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KSO_RS07560	COG1757	Na H antiporter
KSO_RS07565	COG4483	Protein conserved in bacteria
KSO_RS07570	COG1940	carbohydrate kinase activity
KSO_RS07575	COG2866	Carboxypeptidase
KSO_RS07585	COG0011	TIGRFAM Protein of
KSO_RS07595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS07605	COG1393	Belongs to the ArsC family
KSO_RS07615	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS07620	COG1253	flavin adenine dinucleotide binding
KSO_RS07625	COG0598	Magnesium transport protein CorA
KSO_RS07630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KSO_RS07635	COG1459	type II secretion system
KSO_RS07640	COG4537	Required for transformation and DNA binding
KSO_RS07645	COG4970	Tfp pilus assembly protein FimT
KSO_RS07655	COG4940	Competence protein ComGF
KSO_RS07680	COG0681	Belongs to the peptidase S26 family
KSO_RS07690	COG1396	sequence-specific DNA binding
KSO_RS07705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KSO_RS07725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KSO_RS07740	COG1752	Esterase of the alpha-beta hydrolase superfamily
KSO_RS07750	COG3872	metal-dependent enzyme
KSO_RS07760	COG0006	proline dipeptidase activity
KSO_RS07775	COG3854	ATPases associated with a variety of cellular activities
KSO_RS07815	COG0511	ligase activity, forming carbon-carbon bonds
KSO_RS07820	COG0439	Biotin carboxylase
KSO_RS07825	COG1302	Protein conserved in bacteria
KSO_RS07840	COG1570	exodeoxyribonuclease VII activity
KSO_RS07850	COG0142	geranyltranstransferase activity
KSO_RS07860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KSO_RS07870	COG0497	DNA recombination
KSO_RS07875	COG0750	zinc metalloprotease
KSO_RS07880	COG0745	RESPONSE REGULATOR receiver
KSO_RS07885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KSO_RS07900	COG1902	pentaerythritol trinitrate reductase activity
KSO_RS07925	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS07930	COG0584	glycerophosphoryl diester phosphodiesterase
KSO_RS07935	COG0183	Belongs to the thiolase family
KSO_RS07940	COG1250	3-hydroxyacyl-CoA dehydrogenase
KSO_RS07945	COG1960	acyl-CoA dehydrogenase activity
KSO_RS07950	COG0372	Belongs to the citrate synthase family
KSO_RS07955	COG2079	MmgE PrpD family protein
KSO_RS07960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KSO_RS07970	COG3829	transcription factor binding
KSO_RS07970	COG3290	protein histidine kinase activity
KSO_RS07975	COG0280	phosphate acetyltransferase
KSO_RS07980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KSO_RS07985	COG3426	butyrate kinase activity
KSO_RS07990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSO_RS07995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KSO_RS08000	COG0022	dehydrogenase e1 component
KSO_RS08005	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSO_RS08010	COG1597	lipid kinase activity
KSO_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS08025	COG0765	amino acid transport
KSO_RS08030	COG1126	abc transporter atp-binding protein
KSO_RS08035	COG4129	membrane
KSO_RS08040	COG1376	ErfK ybiS ycfS ynhG family protein
KSO_RS08045	COG0346	lactoylglutathione lyase activity
KSO_RS08050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KSO_RS08055	COG2195	Cleaves the N-terminal amino acid of tripeptides
KSO_RS08060	COG0706	membrane insertase activity
KSO_RS08075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KSO_RS08080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KSO_RS08095	COG0596	Alpha beta hydrolase
KSO_RS08115	COG0250	Participates in transcription elongation, termination and antitermination
KSO_RS08120	COG2070	2-Nitropropane dioxygenase
KSO_RS08120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KSO_RS08135	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08145	COG3321	synthase
KSO_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS08145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS08150	COG0300	oxidoreductase activity
KSO_RS08150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08150	COG3321	synthase
KSO_RS08150	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS08155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS08155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08155	COG3321	synthase
KSO_RS08155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08160	COG3321	synthase
KSO_RS08160	COG0300	oxidoreductase activity
KSO_RS08160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08160	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS08165	COG3321	synthase
KSO_RS08165	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS08165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08165	COG0300	oxidoreductase activity
KSO_RS08170	COG3321	synthase
KSO_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS08175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS08175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS08175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS08175	COG3321	synthase
KSO_RS08180	COG2124	cytochrome p450
KSO_RS08185	COG3425	synthase
KSO_RS08190	COG1024	Enoyl-CoA hydratase
KSO_RS08195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KSO_RS08200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS08205	COG0300	oxidoreductase activity
KSO_RS08210	COG3048	D-serine ammonia-lyase activity
KSO_RS08220	COG0346	lactoylglutathione lyase activity
KSO_RS08225	COG0628	permease
KSO_RS08240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KSO_RS08245	COG0456	acetyltransferase
KSO_RS08250	COG2329	Antibiotic biosynthesis monooxygenase
KSO_RS08255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KSO_RS08255	COG0456	acetyltransferase
KSO_RS08260	COG4918	Iron-sulphur cluster biosynthesis
KSO_RS08270	COG1073	alpha beta
KSO_RS08280	COG0667	Aldo Keto reductase
KSO_RS08290	COG0494	nUDIX hydrolase
KSO_RS08295	COG1379	DNA repair
KSO_RS08300	COG1396	sequence-specific DNA binding
KSO_RS08305	COG0252	asparaginase activity
KSO_RS08310	COG1027	Aspartate ammonia-lyase
KSO_RS08315	COG1757	Na H antiporter
KSO_RS08320	COG0281	malic enzyme
KSO_RS08335	COG1300	Membrane
KSO_RS08340	COG0735	belongs to the Fur family
KSO_RS08350	COG4974	Belongs to the 'phage' integrase family
KSO_RS08355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KSO_RS08360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KSO_RS08365	COG1686	Belongs to the peptidase S11 family
KSO_RS08370	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS08380	COG1191	sigma factor activity
KSO_RS08400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KSO_RS08415	COG0697	spore germination
KSO_RS08420	COG0019	diaminopimelate decarboxylase activity
KSO_RS08425	COG4086	secreted protein
KSO_RS08430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KSO_RS08440	COG0681	Belongs to the peptidase S26 family
KSO_RS08450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KSO_RS08450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KSO_RS08455	COG0307	riboflavin synthase, alpha
KSO_RS08470	COG0456	acetyltransferase
KSO_RS08475	COG1547	Domain of unknown function (DUF309)
KSO_RS08495	COG1686	Belongs to the peptidase S11 family
KSO_RS08500	COG2715	membrane protein required for spore maturation
KSO_RS08505	COG0700	Nucleoside recognition
KSO_RS08510	COG1187	pseudouridine synthase activity
KSO_RS08515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS08520	COG1333	cytochrome c biogenesis protein
KSO_RS08525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KSO_RS08530	COG0745	RESPONSE REGULATOR receiver
KSO_RS08535	COG5002	protein histidine kinase activity
KSO_RS08540	COG1595	DNA-templated transcription, initiation
KSO_RS08550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KSO_RS08555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KSO_RS08560	COG1141	Ferredoxin
KSO_RS08565	COG4955	Helix-turn-helix domain
KSO_RS08570	COG0514	ATP-dependent DNA helicase (RecQ)
KSO_RS08575	COG1266	CAAX protease self-immunity
KSO_RS08580	COG1388	LysM domain
KSO_RS08590	COG1408	metallophosphoesterase
KSO_RS08595	COG4862	establishment of competence for transformation
KSO_RS08600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KSO_RS08605	COG0492	ferredoxin-NADP+ reductase activity
KSO_RS08610	COG2339	peptidase activity
KSO_RS08615	COG3773	Cell wall hydrolase
KSO_RS08615	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS08620	COG2959	enzyme of heme biosynthesis
KSO_RS08625	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KSO_RS08635	COG0539	negative regulation of cytoplasmic translation
KSO_RS08670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KSO_RS08675	COG0776	regulation of translation
KSO_RS08690	COG0142	geranyltranstransferase activity
KSO_RS08700	COG0142	geranyltranstransferase activity
KSO_RS08705	COG0105	UTP biosynthetic process
KSO_RS08710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KSO_RS08725	COG4401	Chorismate mutase type I
KSO_RS08730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KSO_RS08765	COG0287	Prephenate dehydrogenase
KSO_RS08775	COG0457	Tetratricopeptide repeat
KSO_RS08790	COG0723	plastoquinol--plastocyanin reductase activity
KSO_RS08795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KSO_RS08800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KSO_RS08800	COG2010	Cytochrome c
KSO_RS08805	COG4347	Protein of unknown function (DUF1405)
KSO_RS08815	COG2140	Oxalate decarboxylase
KSO_RS08820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS08825	COG1694	Mazg nucleotide pyrophosphohydrolase
KSO_RS08840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KSO_RS08845	COG0438	transferase activity, transferring glycosyl groups
KSO_RS08875	COG1199	ATP-dependent helicase activity
KSO_RS08875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KSO_RS08880	COG5353	protein conserved in bacteria
KSO_RS08885	COG0436	Aminotransferase
KSO_RS08895	COG3935	DnaD domain protein
KSO_RS08900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KSO_RS08910	COG4499	WXG100 protein secretion system (Wss), protein YukC
KSO_RS08910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KSO_RS08950	COG0071	Belongs to the small heat shock protein (HSP20) family
KSO_RS08955	COG2190	(PTS) system
KSO_RS08960	COG1111	helicase
KSO_RS08960	COG1205	dead DEAH box helicase
KSO_RS08965	COG3359	exonuclease
KSO_RS08980	COG0116	Belongs to the methyltransferase superfamily
KSO_RS08995	COG1199	ATP-dependent helicase activity
KSO_RS09000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KSO_RS09010	COG2233	PERMEase
KSO_RS09020	COG1335	isochorismatase
KSO_RS09045	COG3424	synthase
KSO_RS09050	COG1755	Isoprenylcysteine carboxyl methyltransferase
KSO_RS09055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KSO_RS09065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KSO_RS09075	COG0328	RNA-DNA hybrid ribonuclease activity
KSO_RS09080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KSO_RS09085	COG0328	RNA-DNA hybrid ribonuclease activity
KSO_RS09105	COG1278	Cold shock
KSO_RS09110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KSO_RS09120	COG0386	Belongs to the glutathione peroxidase family
KSO_RS09125	COG1418	mRNA catabolic process
KSO_RS09130	COG1413	lyase activity
KSO_RS09145	COG2136	Putative SAM-dependent methyltransferase
KSO_RS09145	COG2521	methyltransferase
KSO_RS09160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KSO_RS09165	COG0204	Acyl-transferase
KSO_RS09170	COG1272	protein, Hemolysin III
KSO_RS09175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KSO_RS09180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KSO_RS09190	COG1999	signal sequence binding
KSO_RS09195	COG2755	lipolytic protein G-D-S-L family
KSO_RS09200	COG4698	Protein conserved in bacteria
KSO_RS09205	COG1846	Transcriptional regulator
KSO_RS09220	COG1086	Polysaccharide biosynthesis protein
KSO_RS09230	COG4641	Protein conserved in bacteria
KSO_RS09245	COG0463	Glycosyl transferase, family 2
KSO_RS09250	COG0456	acetyltransferase
KSO_RS09265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KSO_RS09270	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KSO_RS09275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSO_RS09280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KSO_RS09285	COG0456	acetyltransferase
KSO_RS09290	COG1509	lysine 2,3-aminomutase activity
KSO_RS09320	COG0671	phosphoesterase, PA-phosphatase related
KSO_RS09335	COG1876	peptidase activity
KSO_RS09345	COG2226	methyltransferase
KSO_RS09350	COG0793	Belongs to the peptidase S41A family
KSO_RS09350	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS09355	COG2188	Transcriptional regulator
KSO_RS09360	COG2723	6-phospho-beta-galactosidase activity
KSO_RS09370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSO_RS09380	COG0346	lactoylglutathione lyase activity
KSO_RS09385	COG0400	carboxylic ester hydrolase activity
KSO_RS09390	COG0778	Nitroreductase
KSO_RS09395	COG1733	regulation of RNA biosynthetic process
KSO_RS09405	COG1942	4-Oxalocrotonate Tautomerase
KSO_RS09420	COG2962	Rard protein
KSO_RS09430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KSO_RS09435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KSO_RS09440	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS09445	COG0534	Mate efflux family protein
KSO_RS09450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KSO_RS09455	COG1819	glycosyl
KSO_RS09460	COG1388	LysM domain
KSO_RS09460	COG0791	NLP P60 protein
KSO_RS09465	COG2032	superoxide dismutase activity
KSO_RS09470	COG0714	Associated with various cellular activities
KSO_RS09475	COG4548	von Willebrand factor, type A
KSO_RS09485	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSO_RS09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS09495	COG0385	Bile acid
KSO_RS09500	COG0733	neurotransmitter:sodium symporter activity
KSO_RS09505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KSO_RS09510	COG1657	PFAM Prenyltransferase squalene oxidase
KSO_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS09540	COG0071	Belongs to the small heat shock protein (HSP20) family
KSO_RS09555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KSO_RS09560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KSO_RS09565	COG0514	ATP-dependent DNA helicase (RecQ)
KSO_RS09570	COG3584	3D domain protein
KSO_RS09570	COG1388	LysM domain
KSO_RS09580	COG1619	proteins homologs of microcin C7 resistance protein MccF
KSO_RS09595	COG2322	membrane
KSO_RS09600	COG0741	lytic transglycosylase activity
KSO_RS09605	COG0640	Transcriptional regulator
KSO_RS09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS09620	COG1309	transcriptional regulator
KSO_RS09625	COG0662	Cupin 2, conserved barrel domain protein
KSO_RS09625	COG2207	Transcriptional regulator
KSO_RS09630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSO_RS09635	COG1733	regulation of RNA biosynthetic process
KSO_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS09660	COG0243	molybdopterin cofactor binding
KSO_RS09665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KSO_RS09670	COG1070	Carbohydrate kinase
KSO_RS09675	COG2814	Major facilitator Superfamily
KSO_RS09685	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KSO_RS09690	COG0300	oxidoreductase activity
KSO_RS09705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KSO_RS09710	COG0583	DNA-binding transcription factor activity
KSO_RS09715	COG0069	glutamate synthase activity
KSO_RS09715	COG0070	glutamate synthase
KSO_RS09715	COG0067	glutamate synthase
KSO_RS09720	COG0493	'glutamate synthase
KSO_RS09730	COG0604	alcohol dehydrogenase
KSO_RS09745	COG0640	Transcriptional regulator
KSO_RS09750	COG2814	Major facilitator Superfamily
KSO_RS09755	COG0405	Gamma-glutamyltransferase
KSO_RS09760	COG0166	Belongs to the GPI family
KSO_RS09765	COG0582	viral genome integration into host DNA
KSO_RS09780	COG0534	Mate efflux family protein
KSO_RS09785	COG2017	converts alpha-aldose to the beta-anomer
KSO_RS09790	COG2027	D-alanyl-D-alanine carboxypeptidase
KSO_RS09795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS09815	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KSO_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS09825	COG1649	PFAM Uncharacterised BCR, COG1649
KSO_RS09830	COG1960	acyl-CoA dehydrogenase activity
KSO_RS09835	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS09840	COG0439	Biotin carboxylase
KSO_RS09845	COG0511	ligase activity, forming carbon-carbon bonds
KSO_RS09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KSO_RS09855	COG1024	Enoyl-CoA hydratase
KSO_RS09860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KSO_RS09865	COG0586	Pfam SNARE associated Golgi protein
KSO_RS09870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KSO_RS09875	COG2246	polysaccharide biosynthetic process
KSO_RS09885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KSO_RS09905	COG2124	cytochrome p450
KSO_RS09910	COG2610	gluconate transmembrane transporter activity
KSO_RS09915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KSO_RS09920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSO_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS09950	COG3507	Belongs to the glycosyl hydrolase 43 family
KSO_RS09960	COG0745	RESPONSE REGULATOR receiver
KSO_RS09965	COG2205	protein histidine kinase activity
KSO_RS10000	COG2271	Major facilitator Superfamily
KSO_RS10005	COG1609	Transcriptional regulator
KSO_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS10020	COG0800	Aldolase
KSO_RS10025	COG1063	alcohol dehydrogenase
KSO_RS10035	COG1115	amino acid carrier protein
KSO_RS10045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KSO_RS10050	COG0187	DNA topoisomerase II activity
KSO_RS10055	COG1832	CoA-binding protein
KSO_RS10065	COG4841	protein insertion into membrane
KSO_RS10075	COG0824	Thioesterase
KSO_RS10095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS10100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KSO_RS10115	COG0071	Belongs to the small heat shock protein (HSP20) family
KSO_RS10125	COG4846	Membrane protein involved in cytochrome C biogenesis
KSO_RS10130	COG2201	protein-glutamate methylesterase activity
KSO_RS10135	COG0785	Cytochrome C biogenesis protein
KSO_RS10155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KSO_RS10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KSO_RS10195	COG4195	phage-related replication protein
KSO_RS10200	COG0756	dUTP diphosphatase activity
KSO_RS10205	COG5434	Belongs to the glycosyl hydrolase 28 family
KSO_RS10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KSO_RS10225	COG3397	chitin binding
KSO_RS10245	COG0456	acetyltransferase
KSO_RS10265	COG1064	alcohol dehydrogenase
KSO_RS10270	COG2318	DinB family
KSO_RS10275	COG2378	regulation of single-species biofilm formation
KSO_RS10290	COG3848	Pyruvate phosphate dikinase
KSO_RS10290	COG0574	Belongs to the PEP-utilizing enzyme family
KSO_RS10295	COG1070	Carbohydrate kinase
KSO_RS10310	COG3507	Belongs to the glycosyl hydrolase 43 family
KSO_RS10315	COG2211	Major facilitator Superfamily
KSO_RS10325	COG0174	glutamine synthetase
KSO_RS10330	COG0789	Transcriptional regulator
KSO_RS10335	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KSO_RS10340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KSO_RS10345	COG0464	growth
KSO_RS10355	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS10360	COG4112	unkown
KSO_RS10365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KSO_RS10370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KSO_RS10410	COG2076	Multidrug Resistance protein
KSO_RS10420	COG1764	response to oxidative stress
KSO_RS10425	COG4195	phage-related replication protein
KSO_RS10435	COG1404	Belongs to the peptidase S8 family
KSO_RS10445	COG3619	membrane
KSO_RS10450	COG3209	COG3209 Rhs family protein
KSO_RS10455	COG2124	cytochrome p450
KSO_RS10460	COG3321	synthase
KSO_RS10460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KSO_RS10460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS10460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KSO_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS10465	COG3321	synthase
KSO_RS10465	COG4221	oxidoreductase activity
KSO_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS10470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS10470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS10470	COG3321	synthase
KSO_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS10470	COG3321	synthase
KSO_RS10470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS10470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS10470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS10470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS10475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS10475	COG0300	oxidoreductase activity
KSO_RS10475	COG3321	synthase
KSO_RS10475	COG4221	oxidoreductase activity
KSO_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS10480	COG3321	synthase
KSO_RS10480	COG0300	oxidoreductase activity
KSO_RS10480	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS10480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS10485	COG1024	Enoyl-CoA hydratase
KSO_RS10490	COG1024	Enoyl-CoA hydratase
KSO_RS10495	COG3425	synthase
KSO_RS10500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS10545	COG4550	Control of competence regulator ComK, YlbF/YmcA
KSO_RS10565	COG2359	stage V sporulation protein S
KSO_RS10570	COG1692	metallophosphoesterase
KSO_RS10580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KSO_RS10595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KSO_RS10600	COG1426	Protein conserved in bacteria
KSO_RS10615	COG0300	oxidoreductase activity
KSO_RS10620	COG0612	Peptidase, M16
KSO_RS10625	COG0612	Peptidase, M16
KSO_RS10630	COG1033	growth of symbiont in host cell
KSO_RS10630	COG2409	Drug exporters of the RND superfamily
KSO_RS10635	COG1846	Transcriptional regulator
KSO_RS10640	COG2814	Major facilitator Superfamily
KSO_RS10645	COG2188	Transcriptional regulator
KSO_RS10650	COG1674	ftsk spoiiie
KSO_RS10650	COG4980	gas vesicle protein
KSO_RS10660	COG0740	serine-type endopeptidase activity
KSO_RS10665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KSO_RS10675	COG0527	aspartate kinase activity
KSO_RS10680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KSO_RS10685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KSO_RS10690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KSO_RS10695	COG1873	PFAM PRC-barrel domain
KSO_RS10700	COG0612	Peptidase, M16
KSO_RS10705	COG0726	polysaccharide deacetylase
KSO_RS10720	COG0196	riboflavin kinase activity
KSO_RS10735	COG1550	Protein conserved in bacteria
KSO_RS10745	COG1358	cellular component organization or biogenesis
KSO_RS10750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KSO_RS10755	COG0195	Participates in both transcription termination and antitermination
KSO_RS10765	COG2176	DNA-directed DNA polymerase activity
KSO_RS10775	COG0750	zinc metalloprotease
KSO_RS10785	COG4589	Belongs to the CDS family
KSO_RS10790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KSO_RS10820	COG1191	sigma factor activity
KSO_RS10830	COG1776	CheC inhibitor of MCP methylation
KSO_RS10835	COG0835	chemotaxis
KSO_RS10840	COG2198	Histidine kinase
KSO_RS10840	COG0643	Histidine kinase
KSO_RS10845	COG2201	protein-glutamate methylesterase activity
KSO_RS10850	COG0455	bacterial-type flagellum organization
KSO_RS10855	COG1419	protein localization to endoplasmic reticulum
KSO_RS10860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KSO_RS10865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KSO_RS10870	COG1684	flagellar biosynthetic protein fliR
KSO_RS10875	COG1987	bacterial-type flagellum assembly
KSO_RS10880	COG1338	Plays a role in the flagellum-specific transport system
KSO_RS10885	COG3190	flagellar
KSO_RS10890	COG2201	protein-glutamate methylesterase activity
KSO_RS10895	COG1776	CheC inhibitor of MCP methylation
KSO_RS10895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KSO_RS10900	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KSO_RS10905	COG1580	Controls the rotational direction of flagella during chemotaxis
KSO_RS10910	COG1582	Flagellar protein (FlbD)
KSO_RS10915	COG4786	Flagellar basal body rod
KSO_RS10920	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KSO_RS10925	COG3144	bacterial-type flagellum assembly
KSO_RS10930	COG3334	PFAM MgtE intracellular
KSO_RS10935	COG2882	bacterial-type flagellum organization
KSO_RS10940	COG1157	protein secretion by the type III secretion system
KSO_RS10945	COG1317	bacterial-type flagellum organization
KSO_RS10950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KSO_RS10955	COG1766	The M ring may be actively involved in energy transduction
KSO_RS10960	COG1677	Flagellar hook-basal body complex protein FliE
KSO_RS10965	COG1558	bacterial-type flagellum-dependent cell motility
KSO_RS10970	COG1815	bacterial-type flagellum-dependent cell motility
KSO_RS10990	COG4974	Belongs to the 'phage' integrase family
KSO_RS11000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KSO_RS11005	COG0758	DNA mediated transformation
KSO_RS11010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KSO_RS11020	COG2257	FlhB HrpN YscU SpaS Family
KSO_RS11035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KSO_RS11060	COG1837	Belongs to the UPF0109 family
KSO_RS11070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KSO_RS11085	COG0552	protein localization to endoplasmic reticulum
KSO_RS11090	COG1196	nuclear chromosome segregation
KSO_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS11110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KSO_RS11125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KSO_RS11130	COG1760	l-serine dehydratase
KSO_RS11135	COG1760	l-serine dehydratase
KSO_RS11140	COG1461	Dihydroxyacetone kinase
KSO_RS11145	COG1302	Protein conserved in bacteria
KSO_RS11160	COG1564	THIamine pyrophosphokinase
KSO_RS11165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KSO_RS11175	COG2815	serine threonine protein kinase
KSO_RS11175	COG0515	serine threonine protein kinase
KSO_RS11180	COG0631	protein serine/threonine phosphatase activity
KSO_RS11190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KSO_RS11190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KSO_RS11200	COG0242	peptide deformylase activity
KSO_RS11205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KSO_RS11210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KSO_RS11220	COG0194	GDP metabolic process
KSO_RS11230	COG1561	YicC-like family, N-terminal region
KSO_RS11235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KSO_RS11245	COG1648	precorrin-2 dehydrogenase activity
KSO_RS11250	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KSO_RS11255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KSO_RS11270	COG0306	phosphate transporter
KSO_RS11280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KSO_RS11285	COG0284	orotidine-5'-phosphate decarboxylase activity
KSO_RS11300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KSO_RS11305	COG0505	Belongs to the CarA family
KSO_RS11310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KSO_RS11320	COG2233	PERMEase
KSO_RS11330	COG0564	pseudouridine synthase activity
KSO_RS11340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KSO_RS11345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KSO_RS11355	COG3599	regulation of cell shape
KSO_RS11360	COG2302	S4 RNA-binding domain
KSO_RS11365	COG0762	integral membrane protein
KSO_RS11375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KSO_RS11380	COG1496	oxidoreductase activity
KSO_RS11385	COG1873	PFAM PRC-barrel domain
KSO_RS11390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KSO_RS11395	COG1119	ATPase activity
KSO_RS11400	COG1191	sigma factor activity
KSO_RS11405	COG1191	sigma factor activity
KSO_RS11415	COG1404	Belongs to the peptidase S8 family
KSO_RS11415	COG4412	M6 family metalloprotease domain protein
KSO_RS11420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KSO_RS11425	COG0849	cell division
KSO_RS11430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KSO_RS11445	COG0772	Belongs to the SEDS family
KSO_RS11465	COG0768	penicillin binding
KSO_RS11470	COG0768	penicillin binding
KSO_RS11475	COG4839	cell division protein FtsL
KSO_RS11495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KSO_RS11510	COG1399	metal-binding, possibly nucleic acid-binding protein
KSO_RS11520	COG3480	Lon protease (S16) C-terminal proteolytic domain
KSO_RS11525	COG1752	Esterase of the alpha-beta hydrolase superfamily
KSO_RS11530	COG3314	Sporulation integral membrane protein YlbJ
KSO_RS11540	COG0742	ribosomal rna small subunit methyltransferase
KSO_RS11555	COG3679	Belongs to the UPF0342 family
KSO_RS11570	COG2340	Cysteine-rich secretory protein family
KSO_RS11575	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KSO_RS11585	COG3336	cytochrome c oxidase
KSO_RS11590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KSO_RS11595	COG1845	cytochrome c oxidase, subunit III
KSO_RS11600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KSO_RS11605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KSO_RS11605	COG2010	Cytochrome c
KSO_RS11620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KSO_RS11625	COG0772	Belongs to the SEDS family
KSO_RS11635	COG2066	Belongs to the glutaminase family
KSO_RS11640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KSO_RS11645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KSO_RS11655	COG4896	Protein conserved in bacteria
KSO_RS11665	COG1217	gtp-binding protein TYPA
KSO_RS11685	COG3227	Zinc metalloprotease (Elastase)
KSO_RS11695	COG0483	inositol monophosphate 1-phosphatase activity
KSO_RS11720	COG1982	Orn Lys Arg decarboxylase major
KSO_RS11730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS11735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSO_RS11740	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSO_RS11745	COG0022	dehydrogenase e1 component
KSO_RS11750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KSO_RS11755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KSO_RS11760	COG4221	oxidoreductase activity
KSO_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS11760	COG3321	synthase
KSO_RS11760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS11765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS11765	COG0300	oxidoreductase activity
KSO_RS11765	COG3321	synthase
KSO_RS11765	COG4221	oxidoreductase activity
KSO_RS11770	COG4221	oxidoreductase activity
KSO_RS11770	COG3321	synthase
KSO_RS11770	COG0300	oxidoreductase activity
KSO_RS11770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS11775	COG0300	oxidoreductase activity
KSO_RS11775	COG3321	synthase
KSO_RS11775	COG4221	oxidoreductase activity
KSO_RS11775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS11780	COG3321	synthase
KSO_RS11780	COG4221	oxidoreductase activity
KSO_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS11785	COG4221	oxidoreductase activity
KSO_RS11785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSO_RS11785	COG0300	oxidoreductase activity
KSO_RS11785	COG3321	synthase
KSO_RS11790	COG4221	oxidoreductase activity
KSO_RS11790	COG3321	synthase
KSO_RS11790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS11800	COG0497	DNA recombination
KSO_RS11810	COG0242	peptide deformylase activity
KSO_RS11815	COG0561	phosphatase activity
KSO_RS11825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KSO_RS11835	COG0569	domain protein
KSO_RS11840	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KSO_RS11840	COG2105	PFAM AIG2 family protein
KSO_RS11845	COG3852	Histidine kinase
KSO_RS11850	COG2002	toxin-antitoxin pair type II binding
KSO_RS11860	COG1077	Cell shape determining protein MreB Mrl
KSO_RS11865	COG2309	aminopeptidase activity
KSO_RS11870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KSO_RS11875	COG0488	(ABC) transporter
KSO_RS11885	COG0681	Belongs to the peptidase S26 family
KSO_RS11890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSO_RS11890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS11890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSO_RS11895	COG1105	Belongs to the carbohydrate kinase PfkB family
KSO_RS11900	COG1349	DNA-binding transcription factor activity
KSO_RS11905	COG0577	efflux transmembrane transporter activity
KSO_RS11910	COG1136	(ABC) transporter
KSO_RS11915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSO_RS11925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KSO_RS11930	COG0314	molybdopterin synthase activity
KSO_RS11935	COG1763	Mo-molybdopterin cofactor biosynthetic process
KSO_RS11940	COG0303	'Molybdopterin
KSO_RS11945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KSO_RS11965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS11970	COG0668	transmembrane transport
KSO_RS11990	COG0716	FMN binding
KSO_RS12000	COG0716	FMN binding
KSO_RS12005	COG0583	DNA-binding transcription factor activity
KSO_RS12010	COG0517	IMP dehydrogenase activity
KSO_RS12020	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KSO_RS12025	COG4703	Protein of unknown function (DUF1797)
KSO_RS12030	COG2200	EAL domain
KSO_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS12045	COG1408	metallophosphoesterase
KSO_RS12050	COG1376	ErfK ybiS ycfS ynhG family protein
KSO_RS12055	COG2814	Major facilitator Superfamily
KSO_RS12065	COG0835	chemotaxis
KSO_RS12065	COG0784	Response regulator, receiver
KSO_RS12070	COG0436	Aminotransferase
KSO_RS12075	COG4191	Histidine kinase
KSO_RS12080	COG0768	penicillin binding
KSO_RS12085	COG2340	Cysteine-rich secretory protein family
KSO_RS12095	COG2084	Dehydrogenase
KSO_RS12100	COG0840	transmembrane signaling receptor activity
KSO_RS12105	COG1533	DNA photolyase activity
KSO_RS12115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KSO_RS12120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS12125	COG2190	(PTS) system
KSO_RS12125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS12125	COG1263	PTS System
KSO_RS12130	COG3711	transcriptional antiterminator
KSO_RS12135	COG1609	Transcriptional regulator
KSO_RS12140	COG0006	proline dipeptidase activity
KSO_RS12145	COG2217	Heavy metal translocating P-type atpase
KSO_RS12150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS12155	COG2244	polysaccharide biosynthetic process
KSO_RS12160	COG3773	Cell wall hydrolase
KSO_RS12170	COG4873	Protein conserved in bacteria
KSO_RS12185	COG0602	queuosine metabolic process
KSO_RS12190	COG0720	synthase
KSO_RS12205	COG3949	Membrane
KSO_RS12215	COG0542	response to heat
KSO_RS12220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KSO_RS12225	COG1360	Flagellar Motor Protein
KSO_RS12230	COG1846	Transcriptional regulator
KSO_RS12235	COG3852	Histidine kinase
KSO_RS12265	COG0436	Aminotransferase
KSO_RS12270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KSO_RS12285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KSO_RS12290	COG5002	protein histidine kinase activity
KSO_RS12295	COG3594	Acyltransferase
KSO_RS12300	COG2323	membrane
KSO_RS12305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KSO_RS12330	COG1191	sigma factor activity
KSO_RS12335	COG0861	Integral membrane protein TerC family
KSO_RS12340	COG0586	Pfam SNARE associated Golgi protein
KSO_RS12350	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KSO_RS12355	COG3285	dna ligase
KSO_RS12355	COG1793	dna ligase
KSO_RS12360	COG0726	polysaccharide deacetylase
KSO_RS12365	COG1846	Transcriptional regulator
KSO_RS12375	COG0789	Transcriptional regulator
KSO_RS12380	COG2239	Acts as a magnesium transporter
KSO_RS12385	COG3858	chitin binding
KSO_RS12385	COG1388	LysM domain
KSO_RS12390	COG4721	ABC-type cobalt transport system, permease component
KSO_RS12395	COG1122	ATPase activity
KSO_RS12400	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KSO_RS12405	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS12410	COG1404	Belongs to the peptidase S8 family
KSO_RS12420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KSO_RS12425	COG2814	Major facilitator Superfamily
KSO_RS12435	COG0457	Tetratricopeptide repeat
KSO_RS12435	COG0463	Glycosyl transferase, family 2
KSO_RS12450	COG1764	response to oxidative stress
KSO_RS12455	COG1846	Transcriptional regulator
KSO_RS12460	COG1764	response to oxidative stress
KSO_RS12470	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KSO_RS12475	COG0788	formyltetrahydrofolate deformylase activity
KSO_RS12480	COG2076	Multidrug Resistance protein
KSO_RS12485	COG2076	Multidrug Resistance protein
KSO_RS12490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KSO_RS12495	COG1607	acyl-coa hydrolase
KSO_RS12500	COG1834	amidinotransferase
KSO_RS12505	COG2706	6-phosphogluconolactonase activity
KSO_RS12510	COG4608	Belongs to the ABC transporter superfamily
KSO_RS12515	COG0791	NLP P60 protein
KSO_RS12520	COG4948	Mandelate Racemase Muconate Lactonizing
KSO_RS12525	COG1619	proteins homologs of microcin C7 resistance protein MccF
KSO_RS12530	COG4166	transmembrane transport
KSO_RS12535	COG0444	Belongs to the ABC transporter superfamily
KSO_RS12540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KSO_RS12545	COG0601	transmembrane transport
KSO_RS12550	COG2362	D-Aminopeptidase
KSO_RS12555	COG0477	Major facilitator Superfamily
KSO_RS12560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSO_RS12565	COG0463	Glycosyl transferase, family 2
KSO_RS12570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KSO_RS12575	COG0346	lactoylglutathione lyase activity
KSO_RS12580	COG0531	amino acid
KSO_RS12585	COG1392	Phosphate transport regulator
KSO_RS12590	COG0306	phosphate transporter
KSO_RS12605	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS12605	COG5632	N-Acetylmuramoyl-L-alanine amidase
KSO_RS12645	COG3778	Protein conserved in bacteria
KSO_RS12650	COG3299	homolog of phage Mu protein gp47
KSO_RS12655	COG3628	GPW Gp25 family protein
KSO_RS12665	COG4193	domain, Protein
KSO_RS12670	COG1652	LysM domain
KSO_RS12675	COG5412	phage tail tape measure protein
KSO_RS12675	COG3953	SLT domain
KSO_RS12675	COG3953	SLT domain
KSO_RS12675	COG5412	phage tail tape measure protein
KSO_RS12675	COG3953	SLT domain
KSO_RS12675	COG5412	phage tail tape measure protein
KSO_RS12720	COG4653	Phage capsid family
KSO_RS12725	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KSO_RS12730	COG5518	Phage portal protein
KSO_RS12735	COG1783	phage Terminase large subunit
KSO_RS12740	COG5484	DNA packaging
KSO_RS12740	COG3728	DNA packaging
KSO_RS12745	COG1595	DNA-templated transcription, initiation
KSO_RS12760	COG1484	DNA-dependent DNA replication
KSO_RS12765	COG1522	sequence-specific DNA binding
KSO_RS12775	COG1396	sequence-specific DNA binding
KSO_RS12780	COG2856	Zn peptidase
KSO_RS12785	COG4195	phage-related replication protein
KSO_RS12795	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS12795	COG5632	N-Acetylmuramoyl-L-alanine amidase
KSO_RS12795	COG1388	LysM domain
KSO_RS12805	COG0457	Tetratricopeptide repeat
KSO_RS12810	COG2318	DinB family
KSO_RS12815	COG0730	response to heat
KSO_RS12840	COG2197	response regulator
KSO_RS12865	COG2770	Histidine kinase
KSO_RS12865	COG2205	protein histidine kinase activity
KSO_RS12870	COG0745	RESPONSE REGULATOR receiver
KSO_RS12875	COG2721	sulfolactate sulfo-lyase activity
KSO_RS12880	COG0246	Mannitol dehydrogenase
KSO_RS12885	COG1609	Transcriptional regulator
KSO_RS12890	COG2211	Major facilitator Superfamily
KSO_RS12900	COG1252	NADH dehydrogenase
KSO_RS12910	COG4297	protein containing double-stranded beta helix domain
KSO_RS12915	COG0697	spore germination
KSO_RS12920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KSO_RS12925	COG0390	transport system, permease component
KSO_RS12930	COG1587	Uroporphyrinogen-III synthase
KSO_RS12940	COG1819	glycosyl
KSO_RS12945	COG2124	cytochrome p450
KSO_RS12950	COG2427	Protein of unknown function (DUF1641)
KSO_RS12955	COG3383	formate dehydrogenase (NAD+) activity
KSO_RS12965	COG2205	protein histidine kinase activity
KSO_RS12975	COG1285	pathogenesis
KSO_RS12980	COG1846	Transcriptional regulator
KSO_RS12995	COG1349	DNA-binding transcription factor activity
KSO_RS13005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KSO_RS13010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS13010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KSO_RS13015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KSO_RS13020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KSO_RS13025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KSO_RS13035	COG1846	Transcriptional regulator
KSO_RS13045	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KSO_RS13050	COG2367	Beta-lactamase
KSO_RS13055	COG0346	lactoylglutathione lyase activity
KSO_RS13065	COG5444	nuclease activity
KSO_RS13095	COG5632	N-Acetylmuramoyl-L-alanine amidase
KSO_RS13095	COG1388	LysM domain
KSO_RS13095	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS13100	COG4824	toxin secretion phage lysis holin
KSO_RS13200	COG5484	DNA packaging
KSO_RS13220	COG1595	DNA-templated transcription, initiation
KSO_RS13250	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KSO_RS13255	COG1484	DNA-dependent DNA replication
KSO_RS13260	COG3935	DnaD domain protein
KSO_RS13320	COG3620	sequence-specific DNA binding
KSO_RS13330	COG2856	Zn peptidase
KSO_RS13335	COG0582	viral genome integration into host DNA
KSO_RS13345	COG0626	cystathionine gamma-synthase activity
KSO_RS13350	COG0626	cystathionine gamma-synthase activity
KSO_RS13355	COG2382	esterase
KSO_RS13365	COG2153	protein acetylation
KSO_RS13375	COG1131	(ABC) transporter
KSO_RS13395	COG0210	DNA helicase
KSO_RS13450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KSO_RS13455	COG0351	phosphomethylpyrimidine kinase
KSO_RS13460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KSO_RS13470	COG2104	thiamine diphosphate biosynthetic process
KSO_RS13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSO_RS13480	COG0352	thiamine-phosphate diphosphorylase activity
KSO_RS13485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KSO_RS13490	COG0475	glutathione-regulated potassium exporter activity
KSO_RS13490	COG0569	domain protein
KSO_RS13500	COG0564	pseudouridine synthase activity
KSO_RS13505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KSO_RS13510	COG2357	RelA SpoT domain protein
KSO_RS13520	COG4116	CYTH
KSO_RS13525	COG0741	lytic transglycosylase activity
KSO_RS13530	COG2346	COG2346, Truncated hemoglobins
KSO_RS13535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KSO_RS13545	COG1164	Oligoendopeptidase f
KSO_RS13550	COG4469	Competence protein
KSO_RS13555	COG4862	establishment of competence for transformation
KSO_RS13560	COG0861	Integral membrane protein TerC family
KSO_RS13565	COG1393	Belongs to the ArsC family
KSO_RS13570	COG0456	acetyltransferase
KSO_RS13580	COG4608	Belongs to the ABC transporter superfamily
KSO_RS13585	COG0444	Belongs to the ABC transporter superfamily
KSO_RS13590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KSO_RS13595	COG0601	transmembrane transport
KSO_RS13600	COG4166	transmembrane transport
KSO_RS13605	COG0180	Tryptophanyl-tRNA synthetase
KSO_RS13615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KSO_RS13620	COG0601	transmembrane transport
KSO_RS13630	COG4608	Belongs to the ABC transporter superfamily
KSO_RS13635	COG0444	Belongs to the ABC transporter superfamily
KSO_RS13640	COG5504	Zn-dependent protease
KSO_RS13645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KSO_RS13650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KSO_RS13665	COG1744	ABC transporter substrate-binding protein PnrA-like
KSO_RS13675	COG2267	carboxylic ester hydrolase activity
KSO_RS13695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KSO_RS13700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KSO_RS13705	COG0505	Belongs to the CarA family
KSO_RS13710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KSO_RS13720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KSO_RS13730	COG2271	Major facilitator Superfamily
KSO_RS13735	COG0277	FAD linked oxidase domain protein
KSO_RS13745	COG2151	metal-sulfur cluster biosynthetic enzyme
KSO_RS13750	COG1073	alpha beta
KSO_RS13755	COG0561	phosphatase activity
KSO_RS13770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS13775	COG1307	EDD domain protein, DegV family
KSO_RS13780	COG0840	transmembrane signaling receptor activity
KSO_RS13785	COG1744	ABC transporter substrate-binding protein PnrA-like
KSO_RS13790	COG2996	Protein conserved in bacteria
KSO_RS13800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KSO_RS13800	COG0646	methionine synthase
KSO_RS13805	COG2153	protein acetylation
KSO_RS13810	COG1357	PFAM Pentapeptide repeats (8 copies)
KSO_RS13815	COG2318	DinB family
KSO_RS13820	COG0673	inositol 2-dehydrogenase activity
KSO_RS13825	COG1609	Transcriptional regulator
KSO_RS13830	COG1917	Cupin 2, conserved barrel domain protein
KSO_RS13830	COG2207	Transcriptional regulator
KSO_RS13835	COG0534	Mate efflux family protein
KSO_RS13840	COG1562	ergosterol biosynthetic process
KSO_RS13845	COG0367	asparagine synthase
KSO_RS13865	COG0179	Fumarylacetoacetate (FAA) hydrolase
KSO_RS13905	COG1403	HNH endonuclease
KSO_RS13910	COG0419	ATPase involved in DNA repair
KSO_RS13915	COG0420	3'-5' exonuclease activity
KSO_RS13930	COG2323	membrane
KSO_RS13935	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KSO_RS13945	COG2814	Major facilitator Superfamily
KSO_RS13950	COG3180	Ammonia monooxygenase
KSO_RS13955	COG1846	Transcriptional regulator
KSO_RS13960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSO_RS13965	COG0681	Belongs to the peptidase S26 family
KSO_RS13970	COG0398	Pfam SNARE associated Golgi protein
KSO_RS13985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSO_RS14005	COG5646	InterPro IPR014922
KSO_RS14015	COG4903	ComK protein
KSO_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS14030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSO_RS14030	COG0723	plastoquinol--plastocyanin reductase activity
KSO_RS14035	COG0840	transmembrane signaling receptor activity
KSO_RS14040	COG1268	BioY protein
KSO_RS14045	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS14050	COG0183	Belongs to the thiolase family
KSO_RS14055	COG0406	alpha-ribazole phosphatase activity
KSO_RS14060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KSO_RS14070	COG1404	Belongs to the peptidase S8 family
KSO_RS14075	COG0501	Belongs to the peptidase M48B family
KSO_RS14085	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS14090	COG0702	epimerase
KSO_RS14095	COG0095	Lipoate-protein ligase
KSO_RS14100	COG1234	tRNA 3'-trailer cleavage
KSO_RS14105	COG1301	dicarboxylic acid transport
KSO_RS14110	COG1363	Peptidase, m42
KSO_RS14120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KSO_RS14125	COG1511	domain protein
KSO_RS14130	COG1309	transcriptional regulator
KSO_RS14135	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KSO_RS14140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KSO_RS14150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KSO_RS14155	COG2329	Antibiotic biosynthesis monooxygenase
KSO_RS14160	COG3069	C4-dicarboxylate transmembrane transporter activity
KSO_RS14165	COG1473	amidohydrolase
KSO_RS14175	COG4473	ABC transporter
KSO_RS14180	COG1131	(ABC) transporter
KSO_RS14185	COG0537	adenosine 5'-monophosphoramidase activity
KSO_RS14190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KSO_RS14205	COG4980	gas vesicle protein
KSO_RS14245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KSO_RS14260	COG4717	serine-type aminopeptidase activity
KSO_RS14265	COG0420	3'-5' exonuclease activity
KSO_RS14270	COG1668	transmembrane transport
KSO_RS14275	COG4152	abc transporter atp-binding protein
KSO_RS14285	COG1024	Enoyl-CoA hydratase
KSO_RS14295	COG0490	domain, Protein
KSO_RS14300	COG0475	glutathione-regulated potassium exporter activity
KSO_RS14310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KSO_RS14315	COG0561	phosphatase activity
KSO_RS14320	COG4335	DNA alkylation repair
KSO_RS14335	COG0189	ligase activity
KSO_RS14340	COG0189	ligase activity
KSO_RS14355	COG0702	epimerase
KSO_RS14360	COG1132	(ABC) transporter
KSO_RS14365	COG1132	(ABC) transporter
KSO_RS14370	COG0589	response to stress
KSO_RS14380	COG3226	Transcriptional regulator
KSO_RS14385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KSO_RS14390	COG0726	polysaccharide deacetylase
KSO_RS14395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KSO_RS14400	COG0668	transmembrane transport
KSO_RS14405	COG0584	glycerophosphoryl diester phosphodiesterase
KSO_RS14410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KSO_RS14415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KSO_RS14420	COG1253	flavin adenine dinucleotide binding
KSO_RS14425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KSO_RS14430	COG0436	Aminotransferase
KSO_RS14435	COG0789	Transcriptional regulator
KSO_RS14440	COG1253	flavin adenine dinucleotide binding
KSO_RS14445	COG0204	Acyl-transferase
KSO_RS14450	COG1595	DNA-templated transcription, initiation
KSO_RS14465	COG0733	neurotransmitter:sodium symporter activity
KSO_RS14470	COG0531	amino acid
KSO_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS14480	COG0372	Belongs to the citrate synthase family
KSO_RS14485	COG0583	DNA-binding transcription factor activity
KSO_RS14490	COG1388	LysM domain
KSO_RS14490	COG0791	NLP P60 protein
KSO_RS14495	COG1785	Belongs to the alkaline phosphatase family
KSO_RS14500	COG2719	SpoVR family
KSO_RS14505	COG0668	transmembrane transport
KSO_RS14510	COG1959	2 iron, 2 sulfur cluster binding
KSO_RS14515	COG1388	LysM domain
KSO_RS14515	COG0791	NLP P60 protein
KSO_RS14530	COG0431	NADPH-dependent FMN reductase
KSO_RS14535	COG2197	response regulator
KSO_RS14540	COG4585	Histidine kinase
KSO_RS14540	COG2203	Gaf domain
KSO_RS14545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KSO_RS14550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KSO_RS14560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KSO_RS14565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KSO_RS14570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KSO_RS14575	COG3153	acetyltransferase
KSO_RS14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KSO_RS14580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KSO_RS14585	COG0517	IMP dehydrogenase activity
KSO_RS14595	COG0564	pseudouridine synthase activity
KSO_RS14600	COG3764	Sortase (surface protein transpeptidase)
KSO_RS14605	COG1525	nuclease
KSO_RS14605	COG0737	Belongs to the 5'-nucleotidase family
KSO_RS14605	COG4085	toxin activity
KSO_RS14610	COG5577	PFAM Coat F domain
KSO_RS14630	COG1823	symporter activity
KSO_RS14635	COG3706	GGDEF domain
KSO_RS14640	COG1464	Belongs to the NlpA lipoprotein family
KSO_RS14645	COG1278	Cold shock
KSO_RS14650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KSO_RS14655	COG1131	(ABC) transporter
KSO_RS14660	COG1131	(ABC) transporter
KSO_RS14665	COG1725	Transcriptional regulator
KSO_RS14680	COG0655	NAD(P)H dehydrogenase (quinone) activity
KSO_RS14685	COG2814	Major facilitator Superfamily
KSO_RS14690	COG1566	PFAM secretion protein HlyD family protein
KSO_RS14695	COG1846	Transcriptional regulator
KSO_RS14705	COG2766	serine protein kinase
KSO_RS14710	COG1664	Polymer-forming cytoskeletal
KSO_RS14715	COG1664	Polymer-forming cytoskeletal
KSO_RS14720	COG0789	Transcriptional regulator
KSO_RS14725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KSO_RS14735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KSO_RS14740	COG3382	B3 4 domain protein
KSO_RS14750	COG1476	TRANSCRIPTIONal
KSO_RS14770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSO_RS14775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSO_RS14780	COG1116	anion transmembrane transporter activity
KSO_RS14790	COG0753	catalase activity
KSO_RS14795	COG4608	Belongs to the ABC transporter superfamily
KSO_RS14800	COG0444	Belongs to the ABC transporter superfamily
KSO_RS14805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KSO_RS14810	COG0601	transmembrane transport
KSO_RS14815	COG0747	negative chemotaxis
KSO_RS14825	COG0277	FAD linked oxidase domain protein
KSO_RS14835	COG3340	Belongs to the peptidase S51 family
KSO_RS14950	COG0735	belongs to the Fur family
KSO_RS14955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KSO_RS14965	COG4129	membrane
KSO_RS14970	COG1132	(ABC) transporter
KSO_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS15000	COG1194	a g-specific adenine glycosylase
KSO_RS15005	COG1988	membrane-bound metal-dependent
KSO_RS15010	COG4485	Bacterial membrane protein, YfhO
KSO_RS15015	COG0463	Glycosyl transferase, family 2
KSO_RS15020	COG0596	Alpha beta hydrolase
KSO_RS15025	COG5658	integral membrane protein
KSO_RS15030	COG3103	Sh3 type 3 domain protein
KSO_RS15045	COG3591	Belongs to the peptidase S1B family
KSO_RS15055	COG2814	Major facilitator Superfamily
KSO_RS15070	COG1090	epimerase
KSO_RS15080	COG0778	Nitroreductase
KSO_RS15085	COG0384	phenazine biosynthesis protein PhzF
KSO_RS15090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KSO_RS15090	COG0392	lysyltransferase activity
KSO_RS15095	COG1846	Transcriptional regulator
KSO_RS15100	COG2814	Major facilitator Superfamily
KSO_RS15105	COG2318	DinB family
KSO_RS15110	COG2732	(Barnase) inhibitor
KSO_RS15115	COG3848	Pyruvate phosphate dikinase
KSO_RS15115	COG0574	Belongs to the PEP-utilizing enzyme family
KSO_RS15120	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KSO_RS15125	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSO_RS15130	COG1695	Transcriptional regulator
KSO_RS15140	COG2514	catechol 2,3-dioxygenase activity
KSO_RS15145	COG2259	Doxx family
KSO_RS15150	COG1132	(ABC) transporter
KSO_RS15155	COG1132	(ABC) transporter
KSO_RS15160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS15160	COG1263	PTS System
KSO_RS15165	COG1737	Transcriptional regulator
KSO_RS15170	COG1486	melibiose metabolic process
KSO_RS15180	COG3284	Transcriptional regulator
KSO_RS15185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSO_RS15190	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSO_RS15195	COG0022	dehydrogenase e1 component
KSO_RS15200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KSO_RS15205	COG4637	Psort location Cytoplasmic, score
KSO_RS15210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KSO_RS15220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KSO_RS15225	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KSO_RS15230	COG0598	Magnesium transport protein CorA
KSO_RS15240	COG2084	Dehydrogenase
KSO_RS15245	COG0726	polysaccharide deacetylase
KSO_RS15255	COG0535	radical SAM domain protein
KSO_RS15260	COG0668	transmembrane transport
KSO_RS15270	COG0387	Pfam Sodium calcium exchanger
KSO_RS15275	COG0477	Major facilitator Superfamily
KSO_RS15280	COG1295	ribonuclease BN
KSO_RS15285	COG4980	gas vesicle protein
KSO_RS15290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KSO_RS15300	COG2814	Major facilitator Superfamily
KSO_RS15315	COG1609	Transcriptional regulator
KSO_RS15320	COG0693	protein deglycase activity
KSO_RS15325	COG0737	Belongs to the 5'-nucleotidase family
KSO_RS15340	COG0778	Nitroreductase
KSO_RS15345	COG2188	Transcriptional regulator
KSO_RS15350	COG0366	Alpha amylase catalytic
KSO_RS15355	COG1263	PTS System
KSO_RS15355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS15370	COG0071	Belongs to the small heat shock protein (HSP20) family
KSO_RS15380	COG1368	sulfuric ester hydrolase activity
KSO_RS15390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS15390	COG1263	PTS System
KSO_RS15395	COG0024	Methionine aminopeptidase
KSO_RS15405	COG2258	MOSC domain
KSO_RS15415	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KSO_RS15420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS15425	COG2851	Citrate transporter
KSO_RS15430	COG3181	Tripartite tricarboxylate transporter family receptor
KSO_RS15435	COG4565	transcriptional regulatory protein
KSO_RS15440	COG3290	protein histidine kinase activity
KSO_RS15445	COG3764	Sortase (surface protein transpeptidase)
KSO_RS15455	COG3279	Response regulator of the LytR AlgR family
KSO_RS15460	COG0745	RESPONSE REGULATOR receiver
KSO_RS15460	COG2972	Histidine kinase
KSO_RS15490	COG0471	metal ion transport
KSO_RS15495	COG3866	Pectate lyase
KSO_RS15510	COG2130	NADP-dependent
KSO_RS15520	COG0513	Belongs to the DEAD box helicase family
KSO_RS15525	COG0488	(ABC) transporter
KSO_RS15530	COG2814	Major facilitator Superfamily
KSO_RS15535	COG0789	Transcriptional regulator
KSO_RS15540	COG0488	(ABC) transporter
KSO_RS15545	COG0463	Glycosyl transferase, family 2
KSO_RS15545	COG0457	Tetratricopeptide repeat
KSO_RS15550	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS15555	COG0840	transmembrane signaling receptor activity
KSO_RS15560	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS15565	COG0531	amino acid
KSO_RS15570	COG2223	nitrite transmembrane transporter activity
KSO_RS15575	COG1442	glycosyl transferase family 8
KSO_RS15580	COG1216	Glycosyl transferase, family 2
KSO_RS15585	COG1442	glycosyl transferase family 8
KSO_RS15590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSO_RS15595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KSO_RS15600	COG1368	sulfuric ester hydrolase activity
KSO_RS15605	COG2124	cytochrome p450
KSO_RS15605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KSO_RS15615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSO_RS15620	COG1846	Transcriptional regulator
KSO_RS15625	COG0670	Belongs to the BI1 family
KSO_RS15630	COG0196	riboflavin kinase activity
KSO_RS15635	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS15640	COG0346	lactoylglutathione lyase activity
KSO_RS15645	COG2329	Antibiotic biosynthesis monooxygenase
KSO_RS15650	COG2323	membrane
KSO_RS15660	COG0454	-acetyltransferase
KSO_RS15665	COG3546	catalase activity
KSO_RS15700	COG5444	nuclease activity
KSO_RS15715	COG1131	(ABC) transporter
KSO_RS15725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KSO_RS15730	COG1597	lipid kinase activity
KSO_RS15735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KSO_RS15740	COG1309	transcriptional regulator
KSO_RS15760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSO_RS15765	COG1285	pathogenesis
KSO_RS15770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KSO_RS15775	COG4851	CamS sex pheromone cAM373 precursor
KSO_RS15785	COG0210	DNA helicase
KSO_RS15800	COG0069	glutamate synthase activity
KSO_RS15805	COG4496	protein, YerC YecD
KSO_RS15810	COG1470	cell adhesion involved in biofilm formation
KSO_RS15815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KSO_RS15825	COG0151	Belongs to the GarS family
KSO_RS15830	COG0138	bifunctional purine biosynthesis protein purh
KSO_RS15835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KSO_RS15845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KSO_RS15860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KSO_RS15865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KSO_RS15870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KSO_RS15875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KSO_RS15880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KSO_RS15895	COG3064	Membrane
KSO_RS15900	COG2252	PERMEase
KSO_RS15920	COG1305	Transglutaminase-like
KSO_RS15925	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KSO_RS15930	COG0714	Associated with various cellular activities
KSO_RS15935	COG1113	amino acid transport
KSO_RS15940	COG2132	Multicopper oxidase
KSO_RS15955	COG0823	Involved in the tonB-independent uptake of proteins
KSO_RS15960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KSO_RS15965	COG1063	alcohol dehydrogenase
KSO_RS15970	COG1595	DNA-templated transcription, initiation
KSO_RS15980	COG2755	lipolytic protein G-D-S-L family
KSO_RS15980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KSO_RS15985	COG4260	virion core protein, lumpy skin disease virus
KSO_RS15990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KSO_RS15995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KSO_RS16000	COG1842	Phage shock protein A
KSO_RS16010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KSO_RS16015	COG2211	Major facilitator Superfamily
KSO_RS16020	COG1063	alcohol dehydrogenase
KSO_RS16025	COG0457	Tetratricopeptide repeat
KSO_RS16040	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS16055	COG1266	CAAX protease self-immunity
KSO_RS16065	COG0805	protein transport
KSO_RS16070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KSO_RS16085	COG0488	(ABC) transporter
KSO_RS16090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KSO_RS16095	COG0456	acetyltransferase
KSO_RS16100	COG1214	PFAM Peptidase M22, glycoprotease
KSO_RS16105	COG0802	atpase or kinase
KSO_RS16110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KSO_RS16150	COG2814	Major facilitator Superfamily
KSO_RS16155	COG0604	alcohol dehydrogenase
KSO_RS16160	COG3832	glyoxalase III activity
KSO_RS16170	COG0531	amino acid
KSO_RS16175	COG1309	transcriptional regulator
KSO_RS16180	COG2076	Multidrug Resistance protein
KSO_RS16185	COG2076	Multidrug Resistance protein
KSO_RS16190	COG2807	transmembrane transport
KSO_RS16195	COG2186	Transcriptional regulator
KSO_RS16200	COG2188	Transcriptional regulator
KSO_RS16205	COG2814	Major facilitator Superfamily
KSO_RS16210	COG1388	LysM domain
KSO_RS16230	COG1819	glycosyl
KSO_RS16235	COG1802	Transcriptional regulator
KSO_RS16240	COG0473	3-isopropylmalate dehydrogenase activity
KSO_RS16245	COG0596	Alpha beta hydrolase
KSO_RS16250	COG1051	belongs to the nudix hydrolase family
KSO_RS16255	COG0697	spore germination
KSO_RS16260	COG4978	Transcriptional regulator
KSO_RS16260	COG0789	Transcriptional regulator
KSO_RS16265	COG0456	acetyltransferase
KSO_RS16270	COG0730	response to heat
KSO_RS16280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KSO_RS16285	COG2814	Major facilitator Superfamily
KSO_RS16295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KSO_RS16300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KSO_RS16305	COG0488	(ABC) transporter
KSO_RS16310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KSO_RS16315	COG2409	Drug exporters of the RND superfamily
KSO_RS16320	COG2197	response regulator
KSO_RS16325	COG4585	Histidine kinase
KSO_RS16340	COG5577	PFAM Coat F domain
KSO_RS16345	COG1063	alcohol dehydrogenase
KSO_RS16355	COG5577	PFAM Coat F domain
KSO_RS16360	COG1309	transcriptional regulator
KSO_RS16365	COG2814	Major facilitator Superfamily
KSO_RS16380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSO_RS16390	COG0789	Transcriptional regulator
KSO_RS16395	COG1064	alcohol dehydrogenase
KSO_RS16420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KSO_RS16450	COG0277	FAD linked oxidase domain protein
KSO_RS16470	COG0477	Major facilitator Superfamily
KSO_RS16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSO_RS16485	COG1917	Cupin 2, conserved barrel domain protein
KSO_RS16485	COG2207	Transcriptional regulator
KSO_RS16490	COG1473	amidohydrolase
KSO_RS16495	COG0814	amino acid
KSO_RS16500	COG0251	oxidation-reduction process
KSO_RS16505	COG1802	Transcriptional regulator
KSO_RS16510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KSO_RS16520	COG3621	Patatin-like phospholipase
KSO_RS16535	COG1794	racemase activity, acting on amino acids and derivatives
KSO_RS16540	COG0730	response to heat
KSO_RS16545	COG0425	Belongs to the sulfur carrier protein TusA family
KSO_RS16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSO_RS16550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KSO_RS16555	COG0425	Belongs to the sulfur carrier protein TusA family
KSO_RS16555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KSO_RS16560	COG2210	Belongs to the sulfur carrier protein TusA family
KSO_RS16565	COG1937	Protein conserved in bacteria
KSO_RS16570	COG1278	Cold shock
KSO_RS16575	COG2910	NAD(P)H-binding
KSO_RS16580	COG1959	2 iron, 2 sulfur cluster binding
KSO_RS16590	COG2030	dehydratase
KSO_RS16600	COG1846	Transcriptional regulator
KSO_RS16605	COG1764	response to oxidative stress
KSO_RS16615	COG0477	Major facilitator Superfamily
KSO_RS16625	COG5444	nuclease activity
KSO_RS16655	COG1674	ftsk spoiiie
KSO_RS16700	COG2183	response to ionizing radiation
KSO_RS16705	COG2208	phosphoserine phosphatase activity
KSO_RS16710	COG1191	sigma factor activity
KSO_RS16720	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS16725	COG2208	phosphoserine phosphatase activity
KSO_RS16730	COG2172	sigma factor antagonist activity
KSO_RS16735	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS16740	COG1366	Belongs to the anti-sigma-factor antagonist family
KSO_RS16745	COG2337	Toxic component of a toxin-antitoxin (TA) module
KSO_RS16750	COG0864	Transcriptional regulator
KSO_RS16755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KSO_RS16760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KSO_RS16770	COG0705	Rhomboid family
KSO_RS16775	COG3428	Bacterial PH domain
KSO_RS16780	COG3402	PFAM membrane-flanked domain
KSO_RS16785	COG0513	Belongs to the DEAD box helicase family
KSO_RS16790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KSO_RS16800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS16805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KSO_RS16815	COG1960	acyl-CoA dehydrogenase activity
KSO_RS16825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KSO_RS16830	COG1131	(ABC) transporter
KSO_RS16835	COG0628	permease
KSO_RS16840	COG1301	dicarboxylic acid transport
KSO_RS16845	COG4565	transcriptional regulatory protein
KSO_RS16850	COG3290	protein histidine kinase activity
KSO_RS16855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KSO_RS16860	COG3546	catalase activity
KSO_RS16865	COG2329	Antibiotic biosynthesis monooxygenase
KSO_RS16870	COG0662	Cupin 2, conserved barrel domain protein
KSO_RS16875	COG3729	General stress protein
KSO_RS16880	COG2217	Heavy metal translocating P-type atpase
KSO_RS16885	COG2076	Multidrug Resistance protein
KSO_RS16895	COG4876	unkown
KSO_RS16905	COG1914	H( )-stimulated, divalent metal cation uptake system
KSO_RS16935	COG0028	Belongs to the TPP enzyme family
KSO_RS16940	COG0494	nUDIX hydrolase
KSO_RS16945	COG0531	amino acid
KSO_RS16955	COG1215	transferase activity, transferring glycosyl groups
KSO_RS16960	COG5298	Protein conserved in bacteria
KSO_RS16965	COG3706	GGDEF domain
KSO_RS16970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KSO_RS16975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KSO_RS16975	COG0551	DNA topoisomerase type I activity
KSO_RS16980	COG1522	sequence-specific DNA binding
KSO_RS16985	COG2814	Major facilitator Superfamily
KSO_RS16995	COG3871	stress protein (general stress protein 26)
KSO_RS17000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KSO_RS17005	COG1917	Cupin 2, conserved barrel domain protein
KSO_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS17015	COG0318	PFAM AMP-dependent synthetase and ligase
KSO_RS17020	COG3711	transcriptional antiterminator
KSO_RS17025	COG4989	oxidoreductase activity
KSO_RS17030	COG0768	penicillin binding
KSO_RS17035	COG2329	Antibiotic biosynthesis monooxygenase
KSO_RS17045	COG2755	lipolytic protein G-D-S-L family
KSO_RS17050	COG1414	Transcriptional regulator
KSO_RS17055	COG1984	allophanate hydrolase subunit 2
KSO_RS17060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KSO_RS17070	COG1914	H( )-stimulated, divalent metal cation uptake system
KSO_RS17080	COG0561	phosphatase activity
KSO_RS17085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KSO_RS17095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSO_RS17100	COG2213	PTS system mannitol-specific
KSO_RS17110	COG1349	DNA-binding transcription factor activity
KSO_RS17115	COG2372	response to copper ion
KSO_RS17115	COG1276	copper resistance
KSO_RS17120	COG4549	nuclear export factor GLE1
KSO_RS17125	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS17130	COG4975	Glucose uptake
KSO_RS17135	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS17140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KSO_RS17145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSO_RS17150	COG0640	Transcriptional regulator
KSO_RS17155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KSO_RS17160	COG0778	Nitroreductase
KSO_RS17165	COG1309	transcriptional regulator
KSO_RS17170	COG2814	Major facilitator Superfamily
KSO_RS17175	COG4607	ABC-type enterochelin transport system periplasmic component
KSO_RS17180	COG4604	ABC transporter, ATP-binding protein
KSO_RS17185	COG4605	iron ion homeostasis
KSO_RS17190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS17195	COG0527	aspartate kinase activity
KSO_RS17205	COG0457	Tetratricopeptide repeat
KSO_RS17210	COG3850	Histidine kinase
KSO_RS17210	COG5002	protein histidine kinase activity
KSO_RS17215	COG0745	RESPONSE REGULATOR receiver
KSO_RS17220	COG0577	efflux transmembrane transporter activity
KSO_RS17225	COG1136	(ABC) transporter
KSO_RS17230	COG2079	MmgE PrpD family protein
KSO_RS17235	COG1473	amidohydrolase
KSO_RS17240	COG1126	abc transporter atp-binding protein
KSO_RS17245	COG0765	amino acid transport
KSO_RS17250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS17255	COG0456	acetyltransferase
KSO_RS17260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS17265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KSO_RS17275	COG0697	spore germination
KSO_RS17285	COG5434	Belongs to the glycosyl hydrolase 28 family
KSO_RS17290	COG3104	oligopeptide transport
KSO_RS17305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KSO_RS17310	COG0163	prenyltransferase activity
KSO_RS17315	COG0583	DNA-binding transcription factor activity
KSO_RS17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSO_RS17325	COG0765	amino acid transport
KSO_RS17330	COG1126	abc transporter atp-binding protein
KSO_RS17335	COG2364	Membrane
KSO_RS17350	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KSO_RS17355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS17360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSO_RS17365	COG1733	regulation of RNA biosynthetic process
KSO_RS17370	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KSO_RS17375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KSO_RS17380	COG3209	COG3209 Rhs family protein
KSO_RS17390	COG2723	6-phospho-beta-galactosidase activity
KSO_RS17400	COG1714	RDD family
KSO_RS17405	COG1063	alcohol dehydrogenase
KSO_RS17410	COG0523	cobalamin synthesis protein
KSO_RS17415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSO_RS17420	COG2146	nitrite reductase [NAD(P)H] activity
KSO_RS17425	COG1587	Uroporphyrinogen-III synthase
KSO_RS17425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KSO_RS17435	COG2508	Transcriptional regulator
KSO_RS17440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSO_RS17445	COG1012	belongs to the aldehyde dehydrogenase family
KSO_RS17450	COG0506	proline dehydrogenase activity
KSO_RS17455	COG3541	Predicted nucleotidyltransferase
KSO_RS17460	COG3458	cephalosporin-C deacetylase activity
KSO_RS17465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KSO_RS17470	COG2271	Major facilitator Superfamily
KSO_RS17480	COG1660	Displays ATPase and GTPase activities
KSO_RS17495	COG3665	Urea carboxylase-associated protein
KSO_RS17500	COG1113	amino acid transport
KSO_RS17505	COG3403	YqcI/YcgG family
KSO_RS17510	COG1280	lysine exporter protein (LysE YggA)
KSO_RS17515	COG1846	Transcriptional regulator
KSO_RS17520	COG2814	Major facilitator Superfamily
KSO_RS17530	COG0366	Alpha amylase catalytic
KSO_RS17540	COG1288	antiporter activity
KSO_RS17545	COG1473	amidohydrolase
KSO_RS17550	COG2113	Glycine betaine
KSO_RS17555	COG4176	ABC-type proline glycine betaine transport system permease component
KSO_RS17560	COG0517	IMP dehydrogenase activity
KSO_RS17560	COG4175	Glycine betaine
KSO_RS17565	COG0477	Major facilitator Superfamily
KSO_RS17570	COG3853	Toxic anion resistance protein (TelA)
KSO_RS17580	COG0861	Integral membrane protein TerC family
KSO_RS17585	COG2310	stress, protein
KSO_RS17590	COG2310	stress, protein
KSO_RS17595	COG2310	stress, protein
KSO_RS17600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSO_RS17605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KSO_RS17610	COG1121	(ABC) transporter
KSO_RS17615	COG0803	Belongs to the bacterial solute-binding protein 9 family
KSO_RS17620	COG0366	Alpha amylase catalytic
KSO_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
KSO_RS17630	COG0457	Tetratricopeptide repeat
KSO_RS17635	COG1876	peptidase activity
KSO_RS17640	COG1595	DNA-templated transcription, initiation
KSO_RS17645	COG1595	DNA-templated transcription, initiation
KSO_RS17655	COG0667	Aldo Keto reductase
KSO_RS17660	COG3012	SEC-C Motif Domain Protein
KSO_RS17660	COG1405	negative regulation of cell septum assembly
KSO_RS17665	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KSO_RS17675	COG1309	transcriptional regulator
KSO_RS17680	COG0477	Major facilitator Superfamily
KSO_RS17685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KSO_RS17695	COG0805	protein transport
KSO_RS17700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KSO_RS17705	COG3540	Alkaline phosphatase
KSO_RS17710	COG3773	Cell wall hydrolase
KSO_RS17720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KSO_RS17725	COG2259	Doxx family
KSO_RS17730	COG0346	lactoylglutathione lyase activity
KSO_RS17735	COG0778	Nitroreductase
KSO_RS17740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KSO_RS17750	COG3173	Aminoglycoside phosphotransferase
KSO_RS17755	COG0784	Response regulator, receiver
KSO_RS17760	COG4191	Histidine kinase
KSO_RS17765	COG2066	Belongs to the glutaminase family
KSO_RS17770	COG1115	amino acid carrier protein
KSO_RS17775	COG2040	homocysteine
KSO_RS17780	COG0833	amino acid
KSO_RS17785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KSO_RS17790	COG1301	dicarboxylic acid transport
KSO_RS17805	COG0688	phosphatidylethanolamine metabolic process
KSO_RS17810	COG0586	Pfam SNARE associated Golgi protein
KSO_RS17815	COG1183	phosphatidylcholine synthase activity
KSO_RS17825	COG0371	Dehydrogenase
KSO_RS17840	COG3409	Peptidoglycan-binding domain 1 protein
KSO_RS17850	COG2368	4-hydroxyphenylacetate
KSO_RS17860	COG2271	Major facilitator Superfamily
KSO_RS17865	COG0584	glycerophosphoryl diester phosphodiesterase
KSO_RS17880	COG0531	amino acid
KSO_RS17920	COG1131	(ABC) transporter
KSO_RS17925	COG2197	response regulator
KSO_RS17930	COG4585	Histidine kinase
KSO_RS17935	COG1011	Hydrolase
KSO_RS17940	COG1113	amino acid transport
KSO_RS17945	COG1846	Transcriptional regulator
KSO_RS17950	COG1380	Effector of murein hydrolase LrgA
KSO_RS17955	COG1346	cytolysis
KSO_RS18000	COG4856	YbbR-like protein
KSO_RS18005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KSO_RS18010	COG5662	AntiSigma factor
KSO_RS18015	COG1595	DNA-templated transcription, initiation
KSO_RS18045	COG1683	Conserved Protein
KSO_RS18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KSO_RS18060	COG1263	PTS System
KSO_RS18060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KSO_RS18065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KSO_RS18070	COG1472	Belongs to the glycosyl hydrolase 3 family
KSO_RS18075	COG3876	Protein conserved in bacteria
KSO_RS18080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KSO_RS18080	COG2207	Transcriptional regulator
KSO_RS18085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KSO_RS18090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS18095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSO_RS18100	COG2819	hydrolase of the alpha beta superfamily
KSO_RS18105	COG0385	Bile acid
KSO_RS18110	COG0659	secondary active sulfate transmembrane transporter activity
KSO_RS18125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KSO_RS18130	COG0738	Major facilitator superfamily
KSO_RS18250	COG0726	polysaccharide deacetylase
KSO_RS18255	COG2194	sulfuric ester hydrolase activity
KSO_RS18265	COG0489	protein tyrosine kinase activity
KSO_RS18270	COG0860	N-Acetylmuramoyl-L-alanine amidase
KSO_RS18280	COG2318	DinB family
KSO_RS18285	COG2226	methyltransferase
KSO_RS18305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KSO_RS18310	COG1122	ATPase activity
KSO_RS18315	COG1122	ATPase activity
KSO_RS18340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KSO_RS18350	COG0024	Methionine aminopeptidase
KSO_RS18360	COG0201	protein transport
KSO_RS18465	COG0596	Alpha beta hydrolase
KSO_RS18490	COG1358	cellular component organization or biogenesis
KSO_RS18505	COG2813	Specifically methylates the guanine in position
KSO_RS18530	COG0250	Participates in transcription elongation, termination and antitermination
KSO_RS18535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KSO_RS18545	COG1595	DNA-templated transcription, initiation
KSO_RS18550	COG3688	RNA-binding protein containing a PIN domain
KSO_RS18555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KSO_RS18560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KSO_RS18570	COG1045	serine acetyltransferase
KSO_RS18590	COG4956	integral membrane protein (PIN domain superfamily)
KSO_RS18595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KSO_RS18600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KSO_RS18605	COG0542	response to heat
KSO_RS18615	COG3880	PFAM UvrB UvrC protein
KSO_RS18620	COG4463	regulation of RNA biosynthetic process
KSO_RS18700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KSO_RS18705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KSO_RS18710	COG1396	sequence-specific DNA binding
KSO_RS18715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KSO_RS18720	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KSO_RS18725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KSO_RS18730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KSO_RS18735	COG0512	Glutamine amidotransferase of anthranilate synthase
KSO_RS18740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KSO_RS18745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KSO_RS18750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KSO_RS18765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KSO_RS18770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KSO_RS18775	COG0037	tRNA processing
KSO_RS18780	COG0515	serine threonine protein kinase
KSO_RS18785	COG2304	oxidoreductase activity
KSO_RS18790	COG2208	phosphoserine phosphatase activity
KSO_RS18805	COG1098	S1 RNA binding domain
KSO_RS18810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KSO_RS18825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KSO_RS18830	COG3956	TIGRFAM MazG family protein
KSO_RS18835	COG2244	polysaccharide biosynthetic process
KSO_RS18840	COG2002	toxin-antitoxin pair type II binding
KSO_RS18845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KSO_RS18865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KSO_RS18880	COG0251	oxidation-reduction process
KSO_RS18885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KSO_RS18900	COG4466	Protein conserved in bacteria
KSO_RS18910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KSO_RS18915	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KSO_RS18920	COG3583	domain protein
KSO_RS18920	COG3584	3D domain protein
KSO_RS18925	COG0084	hydrolase, TatD family'
KSO_RS18930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSO_RS18930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSO_RS18935	COG2002	toxin-antitoxin pair type II binding
KSO_RS18940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KSO_RS18950	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KSO_RS18960	COG1774	PSP1 C-terminal conserved region
KSO_RS18965	COG0470	DNA polymerase III
KSO_RS18970	COG1728	Protein conserved in bacteria
KSO_RS18975	COG3870	Protein conserved in bacteria
KSO_RS18985	COG1982	Orn Lys Arg decarboxylase major
KSO_RS18990	COG3853	Toxic anion resistance protein (TelA)
KSO_RS18995	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KSO_RS19045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KSO_RS19050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KSO_RS19055	COG0590	tRNA wobble adenosine to inosine editing
KSO_RS19060	COG1335	isochorismatase
KSO_RS19065	COG3858	chitin binding
KSO_RS19065	COG1388	LysM domain
KSO_RS19070	COG1428	Deoxynucleoside kinase
KSO_RS19075	COG1428	Deoxynucleoside kinase
KSO_RS19085	COG1929	Belongs to the glycerate kinase type-1 family
KSO_RS19105	COG1686	Belongs to the peptidase S11 family
KSO_RS19110	COG0517	IMP dehydrogenase activity
KSO_RS19110	COG0516	GMP reductase activity
KSO_RS19145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KSO_RS19150	COG0187	DNA topoisomerase II activity
KSO_RS19165	COG2501	S4 domain
KSO_RS19170	COG0592	DNA-directed DNA polymerase activity
KSO_RS19230	COG5444	nuclease activity