locus-tag	class	description
U722_RS00010	COG0592	DNA-directed DNA polymerase activity
U722_RS00015	COG2501	S4 domain
U722_RS00030	COG0187	DNA topoisomerase II activity
U722_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U722_RS00070	COG0517	IMP dehydrogenase activity
U722_RS00070	COG0516	GMP reductase activity
U722_RS00075	COG1686	Belongs to the peptidase S11 family
U722_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
U722_RS00105	COG1428	Deoxynucleoside kinase
U722_RS00110	COG1428	Deoxynucleoside kinase
U722_RS00115	COG3858	chitin binding
U722_RS00115	COG1388	LysM domain
U722_RS00120	COG1335	isochorismatase
U722_RS00125	COG0590	tRNA wobble adenosine to inosine editing
U722_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
U722_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
U722_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
U722_RS00190	COG3853	Toxic anion resistance protein (TelA)
U722_RS00195	COG1982	Orn Lys Arg decarboxylase major
U722_RS00205	COG3870	Protein conserved in bacteria
U722_RS00210	COG1728	Protein conserved in bacteria
U722_RS00215	COG0470	DNA polymerase III
U722_RS00220	COG1774	PSP1 C-terminal conserved region
U722_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
U722_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
U722_RS00245	COG2002	toxin-antitoxin pair type II binding
U722_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_RS00255	COG0084	hydrolase, TatD family'
U722_RS00260	COG3584	3D domain protein
U722_RS00260	COG3583	domain protein
U722_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
U722_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
U722_RS00280	COG4466	Protein conserved in bacteria
U722_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
U722_RS00300	COG0251	oxidation-reduction process
U722_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
U722_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
U722_RS00340	COG2002	toxin-antitoxin pair type II binding
U722_RS00345	COG2244	polysaccharide biosynthetic process
U722_RS00350	COG3956	TIGRFAM MazG family protein
U722_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
U722_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
U722_RS00375	COG1098	S1 RNA binding domain
U722_RS00390	COG2208	phosphoserine phosphatase activity
U722_RS00395	COG2304	oxidoreductase activity
U722_RS00400	COG0515	serine threonine protein kinase
U722_RS00405	COG0037	tRNA processing
U722_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
U722_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
U722_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U722_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U722_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
U722_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
U722_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U722_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
U722_RS00470	COG1396	sequence-specific DNA binding
U722_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U722_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
U722_RS00540	COG4463	regulation of RNA biosynthetic process
U722_RS00545	COG3880	PFAM UvrB UvrC protein
U722_RS00555	COG0542	response to heat
U722_RS00560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
U722_RS00565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
U722_RS00570	COG4956	integral membrane protein (PIN domain superfamily)
U722_RS00590	COG1045	serine acetyltransferase
U722_RS00600	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
U722_RS00605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U722_RS00610	COG3688	RNA-binding protein containing a PIN domain
U722_RS00615	COG1595	DNA-templated transcription, initiation
U722_RS00625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U722_RS00630	COG0250	Participates in transcription elongation, termination and antitermination
U722_RS00655	COG2813	Specifically methylates the guanine in position
U722_RS00670	COG1358	cellular component organization or biogenesis
U722_RS00695	COG0596	Alpha beta hydrolase
U722_RS00800	COG0201	protein transport
U722_RS00810	COG0024	Methionine aminopeptidase
U722_RS00820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
U722_RS00845	COG1122	ATPase activity
U722_RS00850	COG1122	ATPase activity
U722_RS00855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
U722_RS00875	COG2226	methyltransferase
U722_RS00880	COG2318	DinB family
U722_RS00890	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS00895	COG0489	protein tyrosine kinase activity
U722_RS00905	COG2194	sulfuric ester hydrolase activity
U722_RS00910	COG0726	polysaccharide deacetylase
U722_RS01030	COG0738	Major facilitator superfamily
U722_RS01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U722_RS01050	COG0659	secondary active sulfate transmembrane transporter activity
U722_RS01055	COG0385	Bile acid
U722_RS01060	COG2819	hydrolase of the alpha beta superfamily
U722_RS01065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS01070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS01075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_RS01080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_RS01080	COG2207	Transcriptional regulator
U722_RS01085	COG3876	Protein conserved in bacteria
U722_RS01090	COG1472	Belongs to the glycosyl hydrolase 3 family
U722_RS01095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS01100	COG1263	PTS System
U722_RS01110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_RS01115	COG1683	Conserved Protein
U722_RS01145	COG1595	DNA-templated transcription, initiation
U722_RS01150	COG5662	AntiSigma factor
U722_RS01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
U722_RS01160	COG4856	YbbR-like protein
U722_RS01200	COG1346	cytolysis
U722_RS01205	COG1380	Effector of murein hydrolase LrgA
U722_RS01210	COG1846	Transcriptional regulator
U722_RS01215	COG1113	amino acid transport
U722_RS01220	COG1011	Hydrolase
U722_RS01225	COG4585	Histidine kinase
U722_RS01230	COG2197	response regulator
U722_RS01235	COG1131	(ABC) transporter
U722_RS01255	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
U722_RS01270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS01270	COG3321	synthase
U722_RS01270	COG4221	oxidoreductase activity
U722_RS01275	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS01275	COG3321	synthase
U722_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS01275	COG0300	oxidoreductase activity
U722_RS01275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS01315	COG0531	amino acid
U722_RS01320	COG0584	glycerophosphoryl diester phosphodiesterase
U722_RS01325	COG2271	Major facilitator Superfamily
U722_RS01335	COG2368	4-hydroxyphenylacetate
U722_RS01345	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS01360	COG0371	Dehydrogenase
U722_RS01370	COG1183	phosphatidylcholine synthase activity
U722_RS01375	COG0586	Pfam SNARE associated Golgi protein
U722_RS01380	COG0688	phosphatidylethanolamine metabolic process
U722_RS01395	COG1301	dicarboxylic acid transport
U722_RS01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_RS01405	COG0833	amino acid
U722_RS01410	COG2040	homocysteine
U722_RS01415	COG1115	amino acid carrier protein
U722_RS01420	COG2066	Belongs to the glutaminase family
U722_RS01425	COG4191	Histidine kinase
U722_RS01430	COG0784	Response regulator, receiver
U722_RS01435	COG3173	Aminoglycoside phosphotransferase
U722_RS01445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_RS01450	COG0778	Nitroreductase
U722_RS01455	COG0346	lactoylglutathione lyase activity
U722_RS01460	COG2259	Doxx family
U722_RS01465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS01475	COG3773	Cell wall hydrolase
U722_RS01480	COG3540	Alkaline phosphatase
U722_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U722_RS01490	COG0805	protein transport
U722_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U722_RS01505	COG0477	Major facilitator Superfamily
U722_RS01510	COG1309	transcriptional regulator
U722_RS01515	COG0252	asparaginase activity
U722_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
U722_RS01525	COG1405	negative regulation of cell septum assembly
U722_RS01525	COG3012	SEC-C Motif Domain Protein
U722_RS01530	COG0667	Aldo Keto reductase
U722_RS01540	COG1595	DNA-templated transcription, initiation
U722_RS01545	COG1595	DNA-templated transcription, initiation
U722_RS01550	COG1876	peptidase activity
U722_RS01555	COG0457	Tetratricopeptide repeat
U722_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS01565	COG0366	Alpha amylase catalytic
U722_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
U722_RS01575	COG1121	(ABC) transporter
U722_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U722_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS01590	COG2310	stress, protein
U722_RS01595	COG2310	stress, protein
U722_RS01600	COG2310	stress, protein
U722_RS01605	COG0861	Integral membrane protein TerC family
U722_RS01615	COG3853	Toxic anion resistance protein (TelA)
U722_RS01620	COG0477	Major facilitator Superfamily
U722_RS01625	COG4175	Glycine betaine
U722_RS01625	COG0517	IMP dehydrogenase activity
U722_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
U722_RS01635	COG2113	Glycine betaine
U722_RS01640	COG1473	amidohydrolase
U722_RS01645	COG1288	antiporter activity
U722_RS01655	COG0366	Alpha amylase catalytic
U722_RS01665	COG2814	Major facilitator Superfamily
U722_RS01670	COG1846	Transcriptional regulator
U722_RS01675	COG1280	lysine exporter protein (LysE YggA)
U722_RS01680	COG3403	YqcI/YcgG family
U722_RS01685	COG1113	amino acid transport
U722_RS01690	COG3665	Urea carboxylase-associated protein
U722_RS01705	COG1660	Displays ATPase and GTPase activities
U722_RS01715	COG2271	Major facilitator Superfamily
U722_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
U722_RS01725	COG3458	cephalosporin-C deacetylase activity
U722_RS01730	COG3541	Predicted nucleotidyltransferase
U722_RS01735	COG0506	proline dehydrogenase activity
U722_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_RS01750	COG2508	Transcriptional regulator
U722_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
U722_RS01760	COG1587	Uroporphyrinogen-III synthase
U722_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
U722_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U722_RS01775	COG0523	cobalamin synthesis protein
U722_RS01780	COG1063	alcohol dehydrogenase
U722_RS01785	COG1714	RDD family
U722_RS01795	COG2723	6-phospho-beta-galactosidase activity
U722_RS01805	COG3209	COG3209 Rhs family protein
U722_RS01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
U722_RS01815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
U722_RS01820	COG1733	regulation of RNA biosynthetic process
U722_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS01840	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
U722_RS01855	COG2364	Membrane
U722_RS01860	COG1126	abc transporter atp-binding protein
U722_RS01865	COG0765	amino acid transport
U722_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS01875	COG0583	DNA-binding transcription factor activity
U722_RS01880	COG0163	prenyltransferase activity
U722_RS01885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
U722_RS01900	COG3104	oligopeptide transport
U722_RS01905	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_RS01915	COG0697	spore germination
U722_RS01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U722_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS01935	COG0456	acetyltransferase
U722_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS01945	COG0765	amino acid transport
U722_RS01950	COG1126	abc transporter atp-binding protein
U722_RS01955	COG1473	amidohydrolase
U722_RS01960	COG2079	MmgE PrpD family protein
U722_RS01965	COG1136	(ABC) transporter
U722_RS01970	COG0577	efflux transmembrane transporter activity
U722_RS01975	COG0745	RESPONSE REGULATOR receiver
U722_RS01980	COG3850	Histidine kinase
U722_RS01980	COG5002	protein histidine kinase activity
U722_RS01985	COG0457	Tetratricopeptide repeat
U722_RS01995	COG0527	aspartate kinase activity
U722_RS02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS02005	COG4605	iron ion homeostasis
U722_RS02010	COG4604	ABC transporter, ATP-binding protein
U722_RS02015	COG4607	ABC-type enterochelin transport system periplasmic component
U722_RS02020	COG2814	Major facilitator Superfamily
U722_RS02025	COG1309	transcriptional regulator
U722_RS02030	COG0778	Nitroreductase
U722_RS02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
U722_RS02040	COG0640	Transcriptional regulator
U722_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_RS02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U722_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS02060	COG4975	Glucose uptake
U722_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS02070	COG4549	nuclear export factor GLE1
U722_RS02075	COG1276	copper resistance
U722_RS02075	COG2372	response to copper ion
U722_RS02080	COG1349	DNA-binding transcription factor activity
U722_RS02090	COG2213	PTS system mannitol-specific
U722_RS02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
U722_RS02110	COG0561	phosphatase activity
U722_RS02120	COG1914	H( )-stimulated, divalent metal cation uptake system
U722_RS02130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
U722_RS02135	COG1984	allophanate hydrolase subunit 2
U722_RS02140	COG1414	Transcriptional regulator
U722_RS02145	COG2755	lipolytic protein G-D-S-L family
U722_RS02155	COG2329	Antibiotic biosynthesis monooxygenase
U722_RS02160	COG0768	penicillin binding
U722_RS02165	COG4989	oxidoreductase activity
U722_RS02170	COG3711	transcriptional antiterminator
U722_RS02175	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS02185	COG1917	Cupin 2, conserved barrel domain protein
U722_RS02190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_RS02195	COG3871	stress protein (general stress protein 26)
U722_RS02205	COG2814	Major facilitator Superfamily
U722_RS02210	COG1522	sequence-specific DNA binding
U722_RS02215	COG0551	DNA topoisomerase type I activity
U722_RS02215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U722_RS02220	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
U722_RS02225	COG3706	GGDEF domain
U722_RS02230	COG5298	Protein conserved in bacteria
U722_RS02235	COG1215	transferase activity, transferring glycosyl groups
U722_RS02245	COG0531	amino acid
U722_RS02250	COG0494	nUDIX hydrolase
U722_RS02255	COG0028	Belongs to the TPP enzyme family
U722_RS02285	COG1914	H( )-stimulated, divalent metal cation uptake system
U722_RS02300	COG4876	unkown
U722_RS02310	COG2076	Multidrug Resistance protein
U722_RS02315	COG2217	Heavy metal translocating P-type atpase
U722_RS02320	COG3729	General stress protein
U722_RS02325	COG0662	Cupin 2, conserved barrel domain protein
U722_RS02330	COG2329	Antibiotic biosynthesis monooxygenase
U722_RS02335	COG3546	catalase activity
U722_RS02340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U722_RS02345	COG3290	protein histidine kinase activity
U722_RS02350	COG4565	transcriptional regulatory protein
U722_RS02355	COG1301	dicarboxylic acid transport
U722_RS02360	COG0628	permease
U722_RS02365	COG1131	(ABC) transporter
U722_RS02370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
U722_RS02380	COG1960	acyl-CoA dehydrogenase activity
U722_RS02390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_RS02395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS02405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
U722_RS02410	COG0513	Belongs to the DEAD box helicase family
U722_RS02415	COG3402	PFAM membrane-flanked domain
U722_RS02420	COG3428	Bacterial PH domain
U722_RS02425	COG0705	Rhomboid family
U722_RS02435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
U722_RS02440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U722_RS02445	COG0864	Transcriptional regulator
U722_RS02450	COG2337	Toxic component of a toxin-antitoxin (TA) module
U722_RS02455	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS02465	COG2172	sigma factor antagonist activity
U722_RS02470	COG2208	phosphoserine phosphatase activity
U722_RS02475	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS02485	COG1191	sigma factor activity
U722_RS02490	COG2208	phosphoserine phosphatase activity
U722_RS02495	COG2183	response to ionizing radiation
U722_RS02540	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_RS02550	COG0477	Major facilitator Superfamily
U722_RS02560	COG1764	response to oxidative stress
U722_RS02565	COG1846	Transcriptional regulator
U722_RS02570	COG1959	2 iron, 2 sulfur cluster binding
U722_RS02575	COG2910	NAD(P)H-binding
U722_RS02580	COG1278	Cold shock
U722_RS02585	COG1329	Transcriptional regulator
U722_RS02590	COG1937	Protein conserved in bacteria
U722_RS02595	COG2210	Belongs to the sulfur carrier protein TusA family
U722_RS02605	COG0425	Belongs to the sulfur carrier protein TusA family
U722_RS02605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_RS02610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_RS02610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS02615	COG0425	Belongs to the sulfur carrier protein TusA family
U722_RS02620	COG0730	response to heat
U722_RS02625	COG1794	racemase activity, acting on amino acids and derivatives
U722_RS02640	COG3621	Patatin-like phospholipase
U722_RS02650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U722_RS02655	COG1802	Transcriptional regulator
U722_RS02660	COG0251	oxidation-reduction process
U722_RS02665	COG0814	amino acid
U722_RS02670	COG1473	amidohydrolase
U722_RS02675	COG1917	Cupin 2, conserved barrel domain protein
U722_RS02675	COG2207	Transcriptional regulator
U722_RS02685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_RS02690	COG0477	Major facilitator Superfamily
U722_RS02710	COG0277	FAD linked oxidase domain protein
U722_RS02745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U722_RS02770	COG1064	alcohol dehydrogenase
U722_RS02775	COG0789	Transcriptional regulator
U722_RS02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_RS02800	COG2814	Major facilitator Superfamily
U722_RS02805	COG1309	transcriptional regulator
U722_RS02810	COG5577	PFAM Coat F domain
U722_RS02820	COG1063	alcohol dehydrogenase
U722_RS02825	COG5577	PFAM Coat F domain
U722_RS02835	COG4585	Histidine kinase
U722_RS02840	COG2197	response regulator
U722_RS02845	COG2409	Drug exporters of the RND superfamily
U722_RS02850	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
U722_RS02855	COG0488	(ABC) transporter
U722_RS02860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_RS02865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS02875	COG2814	Major facilitator Superfamily
U722_RS02880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_RS02890	COG0730	response to heat
U722_RS02895	COG0456	acetyltransferase
U722_RS02900	COG0789	Transcriptional regulator
U722_RS02900	COG4978	Transcriptional regulator
U722_RS02905	COG0697	spore germination
U722_RS02910	COG1051	belongs to the nudix hydrolase family
U722_RS02915	COG2226	methyltransferase
U722_RS02920	COG0473	3-isopropylmalate dehydrogenase activity
U722_RS02925	COG1802	Transcriptional regulator
U722_RS02930	COG1819	glycosyl
U722_RS02945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_RS02950	COG1388	LysM domain
U722_RS02955	COG2814	Major facilitator Superfamily
U722_RS02960	COG2188	Transcriptional regulator
U722_RS02965	COG2186	Transcriptional regulator
U722_RS02970	COG2807	transmembrane transport
U722_RS02975	COG2076	Multidrug Resistance protein
U722_RS02980	COG2076	Multidrug Resistance protein
U722_RS02985	COG1309	transcriptional regulator
U722_RS02990	COG0531	amino acid
U722_RS03000	COG3832	glyoxalase III activity
U722_RS03005	COG0604	alcohol dehydrogenase
U722_RS03010	COG2814	Major facilitator Superfamily
U722_RS03050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
U722_RS03055	COG0802	atpase or kinase
U722_RS03060	COG1214	PFAM Peptidase M22, glycoprotease
U722_RS03065	COG0456	acetyltransferase
U722_RS03070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
U722_RS03075	COG0488	(ABC) transporter
U722_RS03090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
U722_RS03095	COG0805	protein transport
U722_RS03105	COG1266	CAAX protease self-immunity
U722_RS03125	COG0457	Tetratricopeptide repeat
U722_RS03130	COG1063	alcohol dehydrogenase
U722_RS03135	COG2211	Major facilitator Superfamily
U722_RS03140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_RS03150	COG1842	Phage shock protein A
U722_RS03155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U722_RS03160	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U722_RS03165	COG4260	virion core protein, lumpy skin disease virus
U722_RS03170	COG2755	lipolytic protein G-D-S-L family
U722_RS03170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
U722_RS03180	COG1595	DNA-templated transcription, initiation
U722_RS03185	COG1063	alcohol dehydrogenase
U722_RS03190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U722_RS03195	COG0823	Involved in the tonB-independent uptake of proteins
U722_RS03210	COG2132	Multicopper oxidase
U722_RS03215	COG1113	amino acid transport
U722_RS03220	COG0714	Associated with various cellular activities
U722_RS03225	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
U722_RS03230	COG1305	Transglutaminase-like
U722_RS03250	COG2252	PERMEase
U722_RS03255	COG3064	Membrane
U722_RS03270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
U722_RS03275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
U722_RS03280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
U722_RS03285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
U722_RS03290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
U722_RS03305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
U722_RS03315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
U722_RS03320	COG0138	bifunctional purine biosynthesis protein purh
U722_RS03325	COG0151	Belongs to the GarS family
U722_RS03335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
U722_RS03340	COG1470	cell adhesion involved in biofilm formation
U722_RS03345	COG4496	protein, YerC YecD
U722_RS03350	COG0069	glutamate synthase activity
U722_RS03365	COG0210	DNA helicase
U722_RS03375	COG4851	CamS sex pheromone cAM373 precursor
U722_RS03380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_RS03385	COG1285	pathogenesis
U722_RS03390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_RS03410	COG1309	transcriptional regulator
U722_RS03415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U722_RS03420	COG1597	lipid kinase activity
U722_RS03425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
U722_RS03435	COG1131	(ABC) transporter
U722_RS03455	COG5444	nuclease activity
U722_RS03490	COG3546	catalase activity
U722_RS03495	COG0454	-acetyltransferase
U722_RS03505	COG2323	membrane
U722_RS03510	COG2329	Antibiotic biosynthesis monooxygenase
U722_RS03515	COG0346	lactoylglutathione lyase activity
U722_RS03520	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS03525	COG0196	riboflavin kinase activity
U722_RS03530	COG0670	Belongs to the BI1 family
U722_RS03535	COG1846	Transcriptional regulator
U722_RS03540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U722_RS03550	COG2124	cytochrome p450
U722_RS03550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_RS03560	COG1368	sulfuric ester hydrolase activity
U722_RS03565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
U722_RS03570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS03575	COG1442	glycosyl transferase family 8
U722_RS03580	COG1216	Glycosyl transferase, family 2
U722_RS03585	COG1442	glycosyl transferase family 8
U722_RS03590	COG2223	nitrite transmembrane transporter activity
U722_RS03595	COG0531	amino acid
U722_RS03600	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS03605	COG0840	transmembrane signaling receptor activity
U722_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS03615	COG0457	Tetratricopeptide repeat
U722_RS03615	COG0463	Glycosyl transferase, family 2
U722_RS03620	COG0488	(ABC) transporter
U722_RS03625	COG0789	Transcriptional regulator
U722_RS03630	COG2814	Major facilitator Superfamily
U722_RS03635	COG0488	(ABC) transporter
U722_RS03640	COG0513	Belongs to the DEAD box helicase family
U722_RS03650	COG2130	NADP-dependent
U722_RS03665	COG3866	Pectate lyase
U722_RS03670	COG0471	metal ion transport
U722_RS03700	COG0745	RESPONSE REGULATOR receiver
U722_RS03700	COG2972	Histidine kinase
U722_RS03705	COG3279	Response regulator of the LytR AlgR family
U722_RS03715	COG3764	Sortase (surface protein transpeptidase)
U722_RS03720	COG3290	protein histidine kinase activity
U722_RS03725	COG4565	transcriptional regulatory protein
U722_RS03730	COG3181	Tripartite tricarboxylate transporter family receptor
U722_RS03735	COG2851	Citrate transporter
U722_RS03740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS03745	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
U722_RS03755	COG2258	MOSC domain
U722_RS03765	COG0024	Methionine aminopeptidase
U722_RS03770	COG1263	PTS System
U722_RS03770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS03780	COG1368	sulfuric ester hydrolase activity
U722_RS03790	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_RS03805	COG1263	PTS System
U722_RS03805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS03810	COG0366	Alpha amylase catalytic
U722_RS03815	COG2188	Transcriptional regulator
U722_RS03820	COG0778	Nitroreductase
U722_RS03835	COG0737	Belongs to the 5'-nucleotidase family
U722_RS03840	COG0693	protein deglycase activity
U722_RS03845	COG1609	Transcriptional regulator
U722_RS03860	COG2814	Major facilitator Superfamily
U722_RS03870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U722_RS03875	COG4980	gas vesicle protein
U722_RS03880	COG1295	ribonuclease BN
U722_RS03885	COG0477	Major facilitator Superfamily
U722_RS03890	COG0387	Pfam Sodium calcium exchanger
U722_RS03900	COG0668	transmembrane transport
U722_RS03905	COG0535	radical SAM domain protein
U722_RS03915	COG0726	polysaccharide deacetylase
U722_RS03920	COG2084	Dehydrogenase
U722_RS03930	COG0598	Magnesium transport protein CorA
U722_RS03935	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
U722_RS03940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
U722_RS03950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
U722_RS03955	COG4637	Psort location Cytoplasmic, score
U722_RS03960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_RS03965	COG0022	dehydrogenase e1 component
U722_RS03970	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_RS03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_RS03980	COG3284	Transcriptional regulator
U722_RS03990	COG1486	melibiose metabolic process
U722_RS03995	COG1737	Transcriptional regulator
U722_RS04000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS04000	COG1263	PTS System
U722_RS04005	COG1132	(ABC) transporter
U722_RS04010	COG1132	(ABC) transporter
U722_RS04015	COG2259	Doxx family
U722_RS04020	COG2514	catechol 2,3-dioxygenase activity
U722_RS04030	COG1695	Transcriptional regulator
U722_RS04035	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_RS04040	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
U722_RS04045	COG0574	Belongs to the PEP-utilizing enzyme family
U722_RS04045	COG3848	Pyruvate phosphate dikinase
U722_RS04050	COG2732	(Barnase) inhibitor
U722_RS04055	COG2318	DinB family
U722_RS04060	COG2814	Major facilitator Superfamily
U722_RS04065	COG1846	Transcriptional regulator
U722_RS04070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
U722_RS04070	COG0392	lysyltransferase activity
U722_RS04075	COG0384	phenazine biosynthesis protein PhzF
U722_RS04080	COG0778	Nitroreductase
U722_RS04090	COG1090	epimerase
U722_RS04105	COG2814	Major facilitator Superfamily
U722_RS04115	COG3591	Belongs to the peptidase S1B family
U722_RS04130	COG3103	Sh3 type 3 domain protein
U722_RS04135	COG5658	integral membrane protein
U722_RS04140	COG0596	Alpha beta hydrolase
U722_RS04145	COG0463	Glycosyl transferase, family 2
U722_RS04150	COG4485	Bacterial membrane protein, YfhO
U722_RS04155	COG1988	membrane-bound metal-dependent
U722_RS04160	COG1194	a g-specific adenine glycosylase
U722_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS04190	COG1132	(ABC) transporter
U722_RS04195	COG4129	membrane
U722_RS04205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U722_RS04210	COG0735	belongs to the Fur family
U722_RS04330	COG3340	Belongs to the peptidase S51 family
U722_RS04340	COG0277	FAD linked oxidase domain protein
U722_RS04350	COG0747	negative chemotaxis
U722_RS04355	COG0601	transmembrane transport
U722_RS04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_RS04365	COG0444	Belongs to the ABC transporter superfamily
U722_RS04370	COG4608	Belongs to the ABC transporter superfamily
U722_RS04375	COG0753	catalase activity
U722_RS04385	COG1116	anion transmembrane transporter activity
U722_RS04390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U722_RS04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U722_RS04415	COG1476	TRANSCRIPTIONal
U722_RS04425	COG3382	B3 4 domain protein
U722_RS04430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
U722_RS04440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
U722_RS04445	COG0789	Transcriptional regulator
U722_RS04450	COG1664	Polymer-forming cytoskeletal
U722_RS04455	COG1664	Polymer-forming cytoskeletal
U722_RS04460	COG2766	serine protein kinase
U722_RS04470	COG1846	Transcriptional regulator
U722_RS04475	COG1566	PFAM secretion protein HlyD family protein
U722_RS04480	COG2814	Major facilitator Superfamily
U722_RS04485	COG0655	NAD(P)H dehydrogenase (quinone) activity
U722_RS04500	COG1725	Transcriptional regulator
U722_RS04505	COG1131	(ABC) transporter
U722_RS04510	COG1131	(ABC) transporter
U722_RS04515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
U722_RS04520	COG1278	Cold shock
U722_RS04525	COG1464	Belongs to the NlpA lipoprotein family
U722_RS04530	COG3706	GGDEF domain
U722_RS04535	COG1823	symporter activity
U722_RS04555	COG5577	PFAM Coat F domain
U722_RS04560	COG0737	Belongs to the 5'-nucleotidase family
U722_RS04560	COG1525	nuclease
U722_RS04560	COG4085	toxin activity
U722_RS04565	COG3764	Sortase (surface protein transpeptidase)
U722_RS04570	COG0564	pseudouridine synthase activity
U722_RS04580	COG0517	IMP dehydrogenase activity
U722_RS04585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U722_RS04590	COG3153	acetyltransferase
U722_RS04590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U722_RS04595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_RS04600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
U722_RS04605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
U722_RS04615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
U722_RS04620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
U722_RS04625	COG2203	Gaf domain
U722_RS04625	COG4585	Histidine kinase
U722_RS04630	COG2197	response regulator
U722_RS04635	COG0431	NADPH-dependent FMN reductase
U722_RS04650	COG0791	NLP P60 protein
U722_RS04650	COG1388	LysM domain
U722_RS04655	COG1959	2 iron, 2 sulfur cluster binding
U722_RS04660	COG0668	transmembrane transport
U722_RS04665	COG2719	SpoVR family
U722_RS04670	COG1785	Belongs to the alkaline phosphatase family
U722_RS04675	COG0791	NLP P60 protein
U722_RS04675	COG1388	LysM domain
U722_RS04680	COG0583	DNA-binding transcription factor activity
U722_RS04685	COG0372	Belongs to the citrate synthase family
U722_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS04695	COG0531	amino acid
U722_RS04700	COG0733	neurotransmitter:sodium symporter activity
U722_RS04715	COG1595	DNA-templated transcription, initiation
U722_RS04720	COG0204	Acyl-transferase
U722_RS04725	COG1253	flavin adenine dinucleotide binding
U722_RS04730	COG0789	Transcriptional regulator
U722_RS04735	COG0436	Aminotransferase
U722_RS04740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_RS04745	COG1253	flavin adenine dinucleotide binding
U722_RS04750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
U722_RS04755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
U722_RS04760	COG0584	glycerophosphoryl diester phosphodiesterase
U722_RS04765	COG0668	transmembrane transport
U722_RS04770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
U722_RS04775	COG0726	polysaccharide deacetylase
U722_RS04780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_RS04785	COG3226	Transcriptional regulator
U722_RS04795	COG0589	response to stress
U722_RS04800	COG1132	(ABC) transporter
U722_RS04805	COG1132	(ABC) transporter
U722_RS04810	COG0702	epimerase
U722_RS04825	COG0189	ligase activity
U722_RS04830	COG0189	ligase activity
U722_RS04845	COG4335	DNA alkylation repair
U722_RS04850	COG0561	phosphatase activity
U722_RS04855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U722_RS04865	COG0475	glutathione-regulated potassium exporter activity
U722_RS04870	COG0490	domain, Protein
U722_RS04880	COG1024	Enoyl-CoA hydratase
U722_RS04890	COG4152	abc transporter atp-binding protein
U722_RS04895	COG1668	transmembrane transport
U722_RS04900	COG0420	3'-5' exonuclease activity
U722_RS04905	COG4717	serine-type aminopeptidase activity
U722_RS04920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U722_RS04960	COG4980	gas vesicle protein
U722_RS04975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
U722_RS04980	COG0537	adenosine 5'-monophosphoramidase activity
U722_RS04985	COG1131	(ABC) transporter
U722_RS04990	COG4473	ABC transporter
U722_RS05000	COG1473	amidohydrolase
U722_RS05005	COG3069	C4-dicarboxylate transmembrane transporter activity
U722_RS05010	COG2329	Antibiotic biosynthesis monooxygenase
U722_RS05015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_RS05025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
U722_RS05030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
U722_RS05035	COG1309	transcriptional regulator
U722_RS05040	COG1511	domain protein
U722_RS05045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_RS05055	COG1363	Peptidase, m42
U722_RS05060	COG1301	dicarboxylic acid transport
U722_RS05065	COG1234	tRNA 3'-trailer cleavage
U722_RS05070	COG0095	Lipoate-protein ligase
U722_RS05075	COG0702	epimerase
U722_RS05080	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS05090	COG0501	Belongs to the peptidase M48B family
U722_RS05095	COG1404	Belongs to the peptidase S8 family
U722_RS05105	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
U722_RS05110	COG0406	alpha-ribazole phosphatase activity
U722_RS05115	COG0183	Belongs to the thiolase family
U722_RS05120	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS05125	COG1268	BioY protein
U722_RS05130	COG0840	transmembrane signaling receptor activity
U722_RS05135	COG0723	plastoquinol--plastocyanin reductase activity
U722_RS05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS05150	COG4903	ComK protein
U722_RS05160	COG5646	InterPro IPR014922
U722_RS05180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_RS05195	COG0398	Pfam SNARE associated Golgi protein
U722_RS05200	COG0681	Belongs to the peptidase S26 family
U722_RS05205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U722_RS05210	COG1846	Transcriptional regulator
U722_RS05215	COG3180	Ammonia monooxygenase
U722_RS05220	COG2814	Major facilitator Superfamily
U722_RS05230	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
U722_RS05235	COG2323	membrane
U722_RS05250	COG0420	3'-5' exonuclease activity
U722_RS05255	COG0419	ATPase involved in DNA repair
U722_RS05260	COG1403	HNH endonuclease
U722_RS05300	COG0179	Fumarylacetoacetate (FAA) hydrolase
U722_RS05320	COG0367	asparagine synthase
U722_RS05325	COG1562	ergosterol biosynthetic process
U722_RS05330	COG0534	Mate efflux family protein
U722_RS05335	COG1917	Cupin 2, conserved barrel domain protein
U722_RS05335	COG2207	Transcriptional regulator
U722_RS05340	COG1609	Transcriptional regulator
U722_RS05345	COG0673	inositol 2-dehydrogenase activity
U722_RS05350	COG2318	DinB family
U722_RS05355	COG1357	PFAM Pentapeptide repeats (8 copies)
U722_RS05360	COG2153	protein acetylation
U722_RS05365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
U722_RS05365	COG0646	methionine synthase
U722_RS05375	COG2996	Protein conserved in bacteria
U722_RS05380	COG1744	ABC transporter substrate-binding protein PnrA-like
U722_RS05385	COG0840	transmembrane signaling receptor activity
U722_RS05390	COG1307	EDD domain protein, DegV family
U722_RS05395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS05410	COG0561	phosphatase activity
U722_RS05415	COG1073	alpha beta
U722_RS05420	COG2151	metal-sulfur cluster biosynthetic enzyme
U722_RS05435	COG0277	FAD linked oxidase domain protein
U722_RS05440	COG2271	Major facilitator Superfamily
U722_RS05450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
U722_RS05460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U722_RS05465	COG0505	Belongs to the CarA family
U722_RS05470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
U722_RS05475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
U722_RS05495	COG2267	carboxylic ester hydrolase activity
U722_RS05505	COG1744	ABC transporter substrate-binding protein PnrA-like
U722_RS05520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_RS05525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U722_RS05530	COG5504	Zn-dependent protease
U722_RS05535	COG0444	Belongs to the ABC transporter superfamily
U722_RS05540	COG4608	Belongs to the ABC transporter superfamily
U722_RS05550	COG0601	transmembrane transport
U722_RS05555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_RS05565	COG0180	Tryptophanyl-tRNA synthetase
U722_RS05570	COG4166	transmembrane transport
U722_RS05575	COG0601	transmembrane transport
U722_RS05580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_RS05585	COG0444	Belongs to the ABC transporter superfamily
U722_RS05590	COG4608	Belongs to the ABC transporter superfamily
U722_RS05600	COG0456	acetyltransferase
U722_RS05605	COG1393	Belongs to the ArsC family
U722_RS05610	COG0861	Integral membrane protein TerC family
U722_RS05615	COG4862	establishment of competence for transformation
U722_RS05620	COG4469	Competence protein
U722_RS05625	COG1164	Oligoendopeptidase f
U722_RS05635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
U722_RS05640	COG2346	COG2346, Truncated hemoglobins
U722_RS05645	COG0741	lytic transglycosylase activity
U722_RS05650	COG4116	CYTH
U722_RS05660	COG2357	RelA SpoT domain protein
U722_RS05665	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
U722_RS05670	COG0564	pseudouridine synthase activity
U722_RS05680	COG0475	glutathione-regulated potassium exporter activity
U722_RS05680	COG0569	domain protein
U722_RS05685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
U722_RS05690	COG0352	thiamine-phosphate diphosphorylase activity
U722_RS05695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_RS05700	COG2104	thiamine diphosphate biosynthetic process
U722_RS05710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_RS05715	COG0351	phosphomethylpyrimidine kinase
U722_RS05720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
U722_RS05775	COG0210	DNA helicase
U722_RS05795	COG1131	(ABC) transporter
U722_RS05805	COG2153	protein acetylation
U722_RS05815	COG2382	esterase
U722_RS05820	COG0626	cystathionine gamma-synthase activity
U722_RS05825	COG0626	cystathionine gamma-synthase activity
U722_RS05845	COG4974	Belongs to the 'phage' integrase family
U722_RS05950	COG5444	nuclease activity
U722_RS05960	COG0346	lactoylglutathione lyase activity
U722_RS05965	COG2367	Beta-lactamase
U722_RS05970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
U722_RS05980	COG1846	Transcriptional regulator
U722_RS05990	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
U722_RS05995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U722_RS06000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
U722_RS06005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS06005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS06010	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_RS06020	COG1349	DNA-binding transcription factor activity
U722_RS06035	COG1285	pathogenesis
U722_RS06040	COG2205	protein histidine kinase activity
U722_RS06050	COG3383	formate dehydrogenase (NAD+) activity
U722_RS06055	COG2427	Protein of unknown function (DUF1641)
U722_RS06060	COG2124	cytochrome p450
U722_RS06065	COG1819	glycosyl
U722_RS06075	COG1587	Uroporphyrinogen-III synthase
U722_RS06080	COG0390	transport system, permease component
U722_RS06085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_RS06090	COG0697	spore germination
U722_RS06095	COG4297	protein containing double-stranded beta helix domain
U722_RS06105	COG1252	NADH dehydrogenase
U722_RS06115	COG2211	Major facilitator Superfamily
U722_RS06120	COG1609	Transcriptional regulator
U722_RS06125	COG0246	Mannitol dehydrogenase
U722_RS06130	COG2721	sulfolactate sulfo-lyase activity
U722_RS06135	COG0745	RESPONSE REGULATOR receiver
U722_RS06140	COG2770	Histidine kinase
U722_RS06140	COG2205	protein histidine kinase activity
U722_RS06160	COG4585	Histidine kinase
U722_RS06165	COG2197	response regulator
U722_RS06190	COG0730	response to heat
U722_RS06195	COG2318	DinB family
U722_RS06200	COG0457	Tetratricopeptide repeat
U722_RS06210	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_RS06210	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS06210	COG1388	LysM domain
U722_RS06220	COG4195	phage-related replication protein
U722_RS06225	COG2856	Zn peptidase
U722_RS06230	COG1396	sequence-specific DNA binding
U722_RS06240	COG1522	sequence-specific DNA binding
U722_RS06245	COG1484	DNA-dependent DNA replication
U722_RS06260	COG1595	DNA-templated transcription, initiation
U722_RS06265	COG3728	DNA packaging
U722_RS06265	COG5484	DNA packaging
U722_RS06270	COG1783	phage Terminase large subunit
U722_RS06275	COG5518	Phage portal protein
U722_RS06280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
U722_RS06285	COG4653	Phage capsid family
U722_RS06330	COG5412	phage tail tape measure protein
U722_RS06330	COG3953	SLT domain
U722_RS06330	COG3953	SLT domain
U722_RS06330	COG5412	phage tail tape measure protein
U722_RS06330	COG5412	phage tail tape measure protein
U722_RS06330	COG3953	SLT domain
U722_RS06335	COG1652	LysM domain
U722_RS06340	COG4193	domain, Protein
U722_RS06350	COG3628	GPW Gp25 family protein
U722_RS06355	COG3299	homolog of phage Mu protein gp47
U722_RS06360	COG3778	Protein conserved in bacteria
U722_RS06400	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_RS06400	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS06415	COG0306	phosphate transporter
U722_RS06420	COG1392	Phosphate transport regulator
U722_RS06425	COG0531	amino acid
U722_RS06430	COG0346	lactoylglutathione lyase activity
U722_RS06435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
U722_RS06440	COG0463	Glycosyl transferase, family 2
U722_RS06445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_RS06450	COG0477	Major facilitator Superfamily
U722_RS06455	COG2362	D-Aminopeptidase
U722_RS06460	COG0601	transmembrane transport
U722_RS06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U722_RS06470	COG0444	Belongs to the ABC transporter superfamily
U722_RS06475	COG4166	transmembrane transport
U722_RS06480	COG1619	proteins homologs of microcin C7 resistance protein MccF
U722_RS06485	COG4948	Mandelate Racemase Muconate Lactonizing
U722_RS06490	COG0791	NLP P60 protein
U722_RS06495	COG4608	Belongs to the ABC transporter superfamily
U722_RS06500	COG2706	6-phosphogluconolactonase activity
U722_RS06505	COG1834	amidinotransferase
U722_RS06510	COG1607	acyl-coa hydrolase
U722_RS06515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
U722_RS06520	COG2076	Multidrug Resistance protein
U722_RS06525	COG2076	Multidrug Resistance protein
U722_RS06530	COG0788	formyltetrahydrofolate deformylase activity
U722_RS06535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
U722_RS06545	COG1764	response to oxidative stress
U722_RS06550	COG1846	Transcriptional regulator
U722_RS06555	COG1764	response to oxidative stress
U722_RS06570	COG0463	Glycosyl transferase, family 2
U722_RS06570	COG0457	Tetratricopeptide repeat
U722_RS06580	COG2814	Major facilitator Superfamily
U722_RS06585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_RS06595	COG1404	Belongs to the peptidase S8 family
U722_RS06600	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS06605	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
U722_RS06610	COG1122	ATPase activity
U722_RS06615	COG4721	ABC-type cobalt transport system, permease component
U722_RS06620	COG1388	LysM domain
U722_RS06620	COG3858	chitin binding
U722_RS06625	COG2239	Acts as a magnesium transporter
U722_RS06630	COG0789	Transcriptional regulator
U722_RS06640	COG1846	Transcriptional regulator
U722_RS06645	COG0726	polysaccharide deacetylase
U722_RS06650	COG3285	dna ligase
U722_RS06650	COG1793	dna ligase
U722_RS06655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
U722_RS06665	COG0586	Pfam SNARE associated Golgi protein
U722_RS06670	COG0861	Integral membrane protein TerC family
U722_RS06675	COG1191	sigma factor activity
U722_RS06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
U722_RS06705	COG2323	membrane
U722_RS06710	COG3594	Acyltransferase
U722_RS06715	COG5002	protein histidine kinase activity
U722_RS06720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U722_RS06735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U722_RS06740	COG0436	Aminotransferase
U722_RS06770	COG3852	Histidine kinase
U722_RS06775	COG1846	Transcriptional regulator
U722_RS06780	COG1360	Flagellar Motor Protein
U722_RS06785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U722_RS06790	COG0542	response to heat
U722_RS06795	COG3949	Membrane
U722_RS06810	COG0720	synthase
U722_RS06815	COG0602	queuosine metabolic process
U722_RS06830	COG4873	Protein conserved in bacteria
U722_RS06840	COG3773	Cell wall hydrolase
U722_RS06845	COG2244	polysaccharide biosynthetic process
U722_RS06850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS06855	COG2217	Heavy metal translocating P-type atpase
U722_RS06860	COG0006	proline dipeptidase activity
U722_RS06865	COG1609	Transcriptional regulator
U722_RS06870	COG3711	transcriptional antiterminator
U722_RS06875	COG2190	(PTS) system
U722_RS06875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS06875	COG1263	PTS System
U722_RS06880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS06885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U722_RS06895	COG1533	DNA photolyase activity
U722_RS06900	COG0840	transmembrane signaling receptor activity
U722_RS06905	COG2084	Dehydrogenase
U722_RS06910	COG2340	Cysteine-rich secretory protein family
U722_RS06915	COG0768	penicillin binding
U722_RS06920	COG4191	Histidine kinase
U722_RS06925	COG0436	Aminotransferase
U722_RS06930	COG0835	chemotaxis
U722_RS06930	COG0784	Response regulator, receiver
U722_RS06940	COG2814	Major facilitator Superfamily
U722_RS06945	COG1376	ErfK ybiS ycfS ynhG family protein
U722_RS06950	COG1408	metallophosphoesterase
U722_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS06965	COG2200	EAL domain
U722_RS06970	COG4703	Protein of unknown function (DUF1797)
U722_RS06975	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
U722_RS06985	COG0517	IMP dehydrogenase activity
U722_RS06990	COG0583	DNA-binding transcription factor activity
U722_RS06995	COG0716	FMN binding
U722_RS07005	COG0716	FMN binding
U722_RS07025	COG0668	transmembrane transport
U722_RS07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS07050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_RS07055	COG0303	'Molybdopterin
U722_RS07060	COG1763	Mo-molybdopterin cofactor biosynthetic process
U722_RS07065	COG0314	molybdopterin synthase activity
U722_RS07070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
U722_RS07080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U722_RS07085	COG1136	(ABC) transporter
U722_RS07090	COG0577	efflux transmembrane transporter activity
U722_RS07095	COG1349	DNA-binding transcription factor activity
U722_RS07100	COG1105	Belongs to the carbohydrate kinase PfkB family
U722_RS07105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS07105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_RS07105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_RS07110	COG0681	Belongs to the peptidase S26 family
U722_RS07120	COG0488	(ABC) transporter
U722_RS07125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U722_RS07130	COG2309	aminopeptidase activity
U722_RS07135	COG1077	Cell shape determining protein MreB Mrl
U722_RS07145	COG2002	toxin-antitoxin pair type II binding
U722_RS07150	COG3852	Histidine kinase
U722_RS07155	COG2105	PFAM AIG2 family protein
U722_RS07155	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
U722_RS07160	COG0569	domain protein
U722_RS07170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
U722_RS07180	COG0561	phosphatase activity
U722_RS07185	COG0242	peptide deformylase activity
U722_RS07195	COG0497	DNA recombination
U722_RS07205	COG4221	oxidoreductase activity
U722_RS07205	COG3321	synthase
U722_RS07205	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS07205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS07210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS07210	COG0300	oxidoreductase activity
U722_RS07210	COG3321	synthase
U722_RS07210	COG4221	oxidoreductase activity
U722_RS07215	COG4221	oxidoreductase activity
U722_RS07215	COG3321	synthase
U722_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS07215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS07220	COG4221	oxidoreductase activity
U722_RS07220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS07220	COG0300	oxidoreductase activity
U722_RS07220	COG3321	synthase
U722_RS07225	COG3321	synthase
U722_RS07225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS07225	COG0300	oxidoreductase activity
U722_RS07225	COG4221	oxidoreductase activity
U722_RS07230	COG4221	oxidoreductase activity
U722_RS07230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS07230	COG0300	oxidoreductase activity
U722_RS07230	COG3321	synthase
U722_RS07235	COG3321	synthase
U722_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS07235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS07235	COG4221	oxidoreductase activity
U722_RS07240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_RS07245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_RS07250	COG0022	dehydrogenase e1 component
U722_RS07255	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_RS07260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_RS07265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS07275	COG1982	Orn Lys Arg decarboxylase major
U722_RS07295	COG0483	inositol monophosphate 1-phosphatase activity
U722_RS07305	COG3227	Zinc metalloprotease (Elastase)
U722_RS07320	COG1595	DNA-templated transcription, initiation
U722_RS07340	COG1217	gtp-binding protein TYPA
U722_RS07350	COG4896	Protein conserved in bacteria
U722_RS07360	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
U722_RS07365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
U722_RS07370	COG2066	Belongs to the glutaminase family
U722_RS07380	COG0772	Belongs to the SEDS family
U722_RS07385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
U722_RS07400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U722_RS07400	COG2010	Cytochrome c
U722_RS07405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U722_RS07410	COG1845	cytochrome c oxidase, subunit III
U722_RS07415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
U722_RS07420	COG3336	cytochrome c oxidase
U722_RS07430	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
U722_RS07435	COG2340	Cysteine-rich secretory protein family
U722_RS07450	COG3679	Belongs to the UPF0342 family
U722_RS07465	COG0742	ribosomal rna small subunit methyltransferase
U722_RS07475	COG3314	Sporulation integral membrane protein YlbJ
U722_RS07480	COG1752	Esterase of the alpha-beta hydrolase superfamily
U722_RS07485	COG3480	Lon protease (S16) C-terminal proteolytic domain
U722_RS07495	COG1399	metal-binding, possibly nucleic acid-binding protein
U722_RS07510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U722_RS07530	COG4839	cell division protein FtsL
U722_RS07535	COG0768	penicillin binding
U722_RS07540	COG0768	penicillin binding
U722_RS07560	COG0772	Belongs to the SEDS family
U722_RS07575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
U722_RS07580	COG0849	cell division
U722_RS07585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
U722_RS07590	COG4412	M6 family metalloprotease domain protein
U722_RS07590	COG1404	Belongs to the peptidase S8 family
U722_RS07600	COG1191	sigma factor activity
U722_RS07605	COG1191	sigma factor activity
U722_RS07610	COG1119	ATPase activity
U722_RS07615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_RS07620	COG1873	PFAM PRC-barrel domain
U722_RS07625	COG1496	oxidoreductase activity
U722_RS07630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
U722_RS07640	COG0762	integral membrane protein
U722_RS07645	COG2302	S4 RNA-binding domain
U722_RS07650	COG3599	regulation of cell shape
U722_RS07660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
U722_RS07665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_RS07675	COG0564	pseudouridine synthase activity
U722_RS07685	COG2233	PERMEase
U722_RS07695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
U722_RS07700	COG0505	Belongs to the CarA family
U722_RS07705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
U722_RS07720	COG0284	orotidine-5'-phosphate decarboxylase activity
U722_RS07725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
U722_RS07735	COG0306	phosphate transporter
U722_RS07750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
U722_RS07755	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
U722_RS07760	COG1648	precorrin-2 dehydrogenase activity
U722_RS07770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
U722_RS07775	COG1561	YicC-like family, N-terminal region
U722_RS07785	COG0194	GDP metabolic process
U722_RS07795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U722_RS07800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U722_RS07805	COG0242	peptide deformylase activity
U722_RS07815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
U722_RS07815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
U722_RS07825	COG0631	protein serine/threonine phosphatase activity
U722_RS07830	COG2815	serine threonine protein kinase
U722_RS07830	COG0515	serine threonine protein kinase
U722_RS07840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U722_RS07845	COG1564	THIamine pyrophosphokinase
U722_RS07860	COG1302	Protein conserved in bacteria
U722_RS07865	COG1461	Dihydroxyacetone kinase
U722_RS07870	COG1760	l-serine dehydratase
U722_RS07875	COG1760	l-serine dehydratase
U722_RS07880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
U722_RS07895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U722_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS07915	COG1196	nuclear chromosome segregation
U722_RS07920	COG0552	protein localization to endoplasmic reticulum
U722_RS07935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
U722_RS07945	COG1837	Belongs to the UPF0109 family
U722_RS07970	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
U722_RS07985	COG2257	FlhB HrpN YscU SpaS Family
U722_RS07995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
U722_RS08000	COG0758	DNA mediated transformation
U722_RS08005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U722_RS08015	COG4974	Belongs to the 'phage' integrase family
U722_RS08035	COG1815	bacterial-type flagellum-dependent cell motility
U722_RS08040	COG1558	bacterial-type flagellum-dependent cell motility
U722_RS08045	COG1677	Flagellar hook-basal body complex protein FliE
U722_RS08050	COG1766	The M ring may be actively involved in energy transduction
U722_RS08055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_RS08060	COG1317	bacterial-type flagellum organization
U722_RS08065	COG1157	protein secretion by the type III secretion system
U722_RS08070	COG2882	bacterial-type flagellum organization
U722_RS08075	COG3334	PFAM MgtE intracellular
U722_RS08080	COG3144	bacterial-type flagellum assembly
U722_RS08085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
U722_RS08090	COG4786	Flagellar basal body rod
U722_RS08095	COG1582	Flagellar protein (FlbD)
U722_RS08100	COG1580	Controls the rotational direction of flagella during chemotaxis
U722_RS08105	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_RS08110	COG1776	CheC inhibitor of MCP methylation
U722_RS08110	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
U722_RS08115	COG2201	protein-glutamate methylesterase activity
U722_RS08120	COG3190	flagellar
U722_RS08125	COG1338	Plays a role in the flagellum-specific transport system
U722_RS08130	COG1987	bacterial-type flagellum assembly
U722_RS08135	COG1684	flagellar biosynthetic protein fliR
U722_RS08140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U722_RS08145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U722_RS08150	COG1419	protein localization to endoplasmic reticulum
U722_RS08155	COG0455	bacterial-type flagellum organization
U722_RS08160	COG2201	protein-glutamate methylesterase activity
U722_RS08165	COG2198	Histidine kinase
U722_RS08165	COG0643	Histidine kinase
U722_RS08170	COG0835	chemotaxis
U722_RS08175	COG1776	CheC inhibitor of MCP methylation
U722_RS08185	COG1191	sigma factor activity
U722_RS08215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
U722_RS08220	COG4589	Belongs to the CDS family
U722_RS08230	COG0750	zinc metalloprotease
U722_RS08240	COG2176	DNA-directed DNA polymerase activity
U722_RS08250	COG0195	Participates in both transcription termination and antitermination
U722_RS08255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
U722_RS08260	COG1358	cellular component organization or biogenesis
U722_RS08270	COG1550	Protein conserved in bacteria
U722_RS08285	COG0196	riboflavin kinase activity
U722_RS08300	COG0726	polysaccharide deacetylase
U722_RS08305	COG0612	Peptidase, M16
U722_RS08310	COG1873	PFAM PRC-barrel domain
U722_RS08315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U722_RS08320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U722_RS08325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
U722_RS08330	COG0527	aspartate kinase activity
U722_RS08340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
U722_RS08345	COG0740	serine-type endopeptidase activity
U722_RS08355	COG4980	gas vesicle protein
U722_RS08355	COG1674	ftsk spoiiie
U722_RS08360	COG2188	Transcriptional regulator
U722_RS08365	COG2814	Major facilitator Superfamily
U722_RS08370	COG1846	Transcriptional regulator
U722_RS08375	COG2409	Drug exporters of the RND superfamily
U722_RS08375	COG1033	growth of symbiont in host cell
U722_RS08380	COG0612	Peptidase, M16
U722_RS08385	COG0612	Peptidase, M16
U722_RS08390	COG0300	oxidoreductase activity
U722_RS08405	COG1426	Protein conserved in bacteria
U722_RS08410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
U722_RS08425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U722_RS08435	COG1692	metallophosphoesterase
U722_RS08440	COG2359	stage V sporulation protein S
U722_RS08460	COG4550	Control of competence regulator ComK, YlbF/YmcA
U722_RS08520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS08525	COG3425	synthase
U722_RS08530	COG1024	Enoyl-CoA hydratase
U722_RS08535	COG1024	Enoyl-CoA hydratase
U722_RS08540	COG3321	synthase
U722_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS08540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS08540	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS08540	COG0300	oxidoreductase activity
U722_RS08545	COG0300	oxidoreductase activity
U722_RS08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS08545	COG3321	synthase
U722_RS08545	COG4221	oxidoreductase activity
U722_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS08550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS08550	COG3321	synthase
U722_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS08550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS08550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS08550	COG3321	synthase
U722_RS08550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS08555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS08555	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS08555	COG3321	synthase
U722_RS08555	COG4221	oxidoreductase activity
U722_RS08560	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
U722_RS08560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U722_RS08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS08560	COG3321	synthase
U722_RS08565	COG2124	cytochrome p450
U722_RS08570	COG3209	COG3209 Rhs family protein
U722_RS08575	COG3619	membrane
U722_RS08585	COG1404	Belongs to the peptidase S8 family
U722_RS08595	COG4195	phage-related replication protein
U722_RS08600	COG1764	response to oxidative stress
U722_RS08610	COG2076	Multidrug Resistance protein
U722_RS08650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U722_RS08655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U722_RS08665	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS08675	COG0464	growth
U722_RS08680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
U722_RS08685	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
U722_RS08690	COG0789	Transcriptional regulator
U722_RS08695	COG0174	glutamine synthetase
U722_RS08705	COG2211	Major facilitator Superfamily
U722_RS08710	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_RS08725	COG1070	Carbohydrate kinase
U722_RS08730	COG3848	Pyruvate phosphate dikinase
U722_RS08730	COG0574	Belongs to the PEP-utilizing enzyme family
U722_RS08745	COG1064	alcohol dehydrogenase
U722_RS08785	COG3397	chitin binding
U722_RS08800	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_RS08810	COG0756	dUTP diphosphatase activity
U722_RS08815	COG4195	phage-related replication protein
U722_RS08850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U722_RS08860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U722_RS08880	COG0785	Cytochrome C biogenesis protein
U722_RS08885	COG2201	protein-glutamate methylesterase activity
U722_RS08890	COG4846	Membrane protein involved in cytochrome C biogenesis
U722_RS08900	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_RS08915	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
U722_RS08920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS08935	COG0824	Thioesterase
U722_RS08945	COG4841	protein insertion into membrane
U722_RS08955	COG1832	CoA-binding protein
U722_RS08960	COG0187	DNA topoisomerase II activity
U722_RS08965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
U722_RS08975	COG1115	amino acid carrier protein
U722_RS08985	COG1063	alcohol dehydrogenase
U722_RS08990	COG0800	Aldolase
U722_RS08995	COG1312	Catalyzes the dehydration of D-mannonate
U722_RS09000	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS09005	COG1609	Transcriptional regulator
U722_RS09010	COG2271	Major facilitator Superfamily
U722_RS09010	COG2271	Major facilitator Superfamily
U722_RS09045	COG2205	protein histidine kinase activity
U722_RS09050	COG0745	RESPONSE REGULATOR receiver
U722_RS09060	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS09090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U722_RS09095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U722_RS09100	COG2610	gluconate transmembrane transporter activity
U722_RS09105	COG2124	cytochrome p450
U722_RS09125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_RS09135	COG2246	polysaccharide biosynthetic process
U722_RS09140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U722_RS09145	COG0586	Pfam SNARE associated Golgi protein
U722_RS09150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U722_RS09155	COG1024	Enoyl-CoA hydratase
U722_RS09160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
U722_RS09165	COG0511	ligase activity, forming carbon-carbon bonds
U722_RS09170	COG0439	Biotin carboxylase
U722_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS09180	COG1960	acyl-CoA dehydrogenase activity
U722_RS09185	COG1649	PFAM Uncharacterised BCR, COG1649
U722_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS09195	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
U722_RS09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS09215	COG2027	D-alanyl-D-alanine carboxypeptidase
U722_RS09220	COG2017	converts alpha-aldose to the beta-anomer
U722_RS09225	COG0534	Mate efflux family protein
U722_RS09240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS09245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS09255	COG5444	nuclease activity
U722_RS09270	COG5632	N-Acetylmuramoyl-L-alanine amidase
U722_RS09270	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS09275	COG4824	toxin secretion phage lysis holin
U722_RS09295	COG5434	Belongs to the glycosyl hydrolase 28 family
U722_RS09300	COG1705	Flagellar rod assembly protein muramidase FlgJ
U722_RS09300	COG1388	LysM domain
U722_RS09375	COG1802	Transcriptional regulator
U722_RS09375	COG4626	Terminase
U722_RS09405	COG0582	viral genome integration into host DNA
U722_RS09410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
U722_RS09515	COG0582	viral genome integration into host DNA
U722_RS09520	COG0166	Belongs to the GPI family
U722_RS09525	COG0405	Gamma-glutamyltransferase
U722_RS09530	COG2814	Major facilitator Superfamily
U722_RS09535	COG0640	Transcriptional regulator
U722_RS09550	COG0604	alcohol dehydrogenase
U722_RS09555	COG0493	'glutamate synthase
U722_RS09560	COG0069	glutamate synthase activity
U722_RS09560	COG0070	glutamate synthase
U722_RS09560	COG0067	glutamate synthase
U722_RS09565	COG0583	DNA-binding transcription factor activity
U722_RS09570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
U722_RS09585	COG0300	oxidoreductase activity
U722_RS09590	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
U722_RS09600	COG2814	Major facilitator Superfamily
U722_RS09605	COG1070	Carbohydrate kinase
U722_RS09610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U722_RS09615	COG0243	molybdopterin cofactor binding
U722_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS09640	COG1733	regulation of RNA biosynthetic process
U722_RS09645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_RS09650	COG0662	Cupin 2, conserved barrel domain protein
U722_RS09650	COG2207	Transcriptional regulator
U722_RS09655	COG1309	transcriptional regulator
U722_RS09660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS09670	COG0640	Transcriptional regulator
U722_RS09675	COG0741	lytic transglycosylase activity
U722_RS09680	COG2322	membrane
U722_RS09695	COG1619	proteins homologs of microcin C7 resistance protein MccF
U722_RS09705	COG1388	LysM domain
U722_RS09705	COG3584	3D domain protein
U722_RS09710	COG0514	ATP-dependent DNA helicase (RecQ)
U722_RS09715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
U722_RS09720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_RS09735	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS09765	COG1657	PFAM Prenyltransferase squalene oxidase
U722_RS09770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U722_RS09775	COG0733	neurotransmitter:sodium symporter activity
U722_RS09780	COG0385	Bile acid
U722_RS09785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS09790	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_RS09800	COG4548	von Willebrand factor, type A
U722_RS09805	COG0714	Associated with various cellular activities
U722_RS09810	COG2032	superoxide dismutase activity
U722_RS09815	COG1388	LysM domain
U722_RS09815	COG0791	NLP P60 protein
U722_RS09820	COG1819	glycosyl
U722_RS09825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
U722_RS09830	COG0534	Mate efflux family protein
U722_RS09835	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS09840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_RS09845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_RS09855	COG2962	Rard protein
U722_RS09870	COG1942	4-Oxalocrotonate Tautomerase
U722_RS09880	COG1733	regulation of RNA biosynthetic process
U722_RS09885	COG0778	Nitroreductase
U722_RS09890	COG0400	carboxylic ester hydrolase activity
U722_RS09895	COG0346	lactoylglutathione lyase activity
U722_RS09905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U722_RS09915	COG2723	6-phospho-beta-galactosidase activity
U722_RS09920	COG2188	Transcriptional regulator
U722_RS09925	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS09925	COG0793	Belongs to the peptidase S41A family
U722_RS09930	COG2226	methyltransferase
U722_RS09940	COG1876	peptidase activity
U722_RS09955	COG0671	phosphoesterase, PA-phosphatase related
U722_RS09985	COG1509	lysine 2,3-aminomutase activity
U722_RS09990	COG0456	acetyltransferase
U722_RS09995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_RS10000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U722_RS10005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U722_RS10010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U722_RS10015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
U722_RS10025	COG0456	acetyltransferase
U722_RS10030	COG0463	Glycosyl transferase, family 2
U722_RS10045	COG4641	Protein conserved in bacteria
U722_RS10055	COG1086	Polysaccharide biosynthesis protein
U722_RS10085	COG1793	dna ligase
U722_RS10100	COG1388	LysM domain
U722_RS10105	COG0457	Tetratricopeptide repeat
U722_RS10150	COG5444	nuclease activity
U722_RS10155	COG4282	regulation of fungal-type cell wall biogenesis
U722_RS10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
U722_RS10185	COG1846	Transcriptional regulator
U722_RS10190	COG4698	Protein conserved in bacteria
U722_RS10195	COG2755	lipolytic protein G-D-S-L family
U722_RS10200	COG1999	signal sequence binding
U722_RS10210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U722_RS10215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
U722_RS10220	COG1272	protein, Hemolysin III
U722_RS10225	COG0204	Acyl-transferase
U722_RS10230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U722_RS10245	COG2521	methyltransferase
U722_RS10245	COG2136	Putative SAM-dependent methyltransferase
U722_RS10260	COG1413	lyase activity
U722_RS10265	COG1418	mRNA catabolic process
U722_RS10270	COG0386	Belongs to the glutathione peroxidase family
U722_RS10280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
U722_RS10285	COG1278	Cold shock
U722_RS10305	COG0328	RNA-DNA hybrid ribonuclease activity
U722_RS10310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
U722_RS10315	COG0328	RNA-DNA hybrid ribonuclease activity
U722_RS10325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_RS10335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
U722_RS10340	COG1755	Isoprenylcysteine carboxyl methyltransferase
U722_RS10345	COG3424	synthase
U722_RS10370	COG1335	isochorismatase
U722_RS10380	COG2233	PERMEase
U722_RS10390	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
U722_RS10395	COG1199	ATP-dependent helicase activity
U722_RS10405	COG0116	Belongs to the methyltransferase superfamily
U722_RS10420	COG3359	exonuclease
U722_RS10430	COG2190	(PTS) system
U722_RS10435	COG0071	Belongs to the small heat shock protein (HSP20) family
U722_RS10475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_RS10475	COG4499	WXG100 protein secretion system (Wss), protein YukC
U722_RS10485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
U722_RS10490	COG3935	DnaD domain protein
U722_RS10500	COG0436	Aminotransferase
U722_RS10505	COG5353	protein conserved in bacteria
U722_RS10510	COG1199	ATP-dependent helicase activity
U722_RS10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U722_RS10540	COG0438	transferase activity, transferring glycosyl groups
U722_RS10545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_RS10560	COG1694	Mazg nucleotide pyrophosphohydrolase
U722_RS10565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS10570	COG2140	Oxalate decarboxylase
U722_RS10580	COG4347	Protein of unknown function (DUF1405)
U722_RS10585	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
U722_RS10585	COG2010	Cytochrome c
U722_RS10590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
U722_RS10595	COG0723	plastoquinol--plastocyanin reductase activity
U722_RS10610	COG0457	Tetratricopeptide repeat
U722_RS10620	COG0287	Prephenate dehydrogenase
U722_RS10655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
U722_RS10660	COG4401	Chorismate mutase type I
U722_RS10675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
U722_RS10680	COG0105	UTP biosynthetic process
U722_RS10685	COG0142	geranyltranstransferase activity
U722_RS10695	COG0142	geranyltranstransferase activity
U722_RS10710	COG0776	regulation of translation
U722_RS10715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
U722_RS10750	COG0539	negative regulation of cytoplasmic translation
U722_RS10760	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
U722_RS10765	COG2959	enzyme of heme biosynthesis
U722_RS10770	COG3773	Cell wall hydrolase
U722_RS10770	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS10775	COG2339	peptidase activity
U722_RS10780	COG0492	ferredoxin-NADP+ reductase activity
U722_RS10785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_RS10790	COG4862	establishment of competence for transformation
U722_RS10795	COG1408	metallophosphoesterase
U722_RS10805	COG1388	LysM domain
U722_RS10810	COG1266	CAAX protease self-immunity
U722_RS10815	COG0514	ATP-dependent DNA helicase (RecQ)
U722_RS10820	COG4955	Helix-turn-helix domain
U722_RS10825	COG1141	Ferredoxin
U722_RS10830	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
U722_RS10835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U722_RS10845	COG1595	DNA-templated transcription, initiation
U722_RS10850	COG5002	protein histidine kinase activity
U722_RS10855	COG0745	RESPONSE REGULATOR receiver
U722_RS10860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U722_RS10865	COG1333	cytochrome c biogenesis protein
U722_RS10870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS10875	COG1187	pseudouridine synthase activity
U722_RS10880	COG0700	Nucleoside recognition
U722_RS10885	COG2715	membrane protein required for spore maturation
U722_RS10890	COG1686	Belongs to the peptidase S11 family
U722_RS10910	COG1547	Domain of unknown function (DUF309)
U722_RS10915	COG0456	acetyltransferase
U722_RS10930	COG0307	riboflavin synthase, alpha
U722_RS10935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U722_RS10935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U722_RS10945	COG0681	Belongs to the peptidase S26 family
U722_RS10955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
U722_RS10960	COG4086	secreted protein
U722_RS10965	COG0019	diaminopimelate decarboxylase activity
U722_RS10970	COG0697	spore germination
U722_RS10985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U722_RS11005	COG1191	sigma factor activity
U722_RS11015	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS11020	COG1686	Belongs to the peptidase S11 family
U722_RS11025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
U722_RS11030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
U722_RS11035	COG4974	Belongs to the 'phage' integrase family
U722_RS11045	COG0735	belongs to the Fur family
U722_RS11050	COG1300	Membrane
U722_RS11065	COG0281	malic enzyme
U722_RS11070	COG1757	Na H antiporter
U722_RS11075	COG1027	Aspartate ammonia-lyase
U722_RS11080	COG0252	asparaginase activity
U722_RS11085	COG1396	sequence-specific DNA binding
U722_RS11090	COG1379	DNA repair
U722_RS11095	COG0494	nUDIX hydrolase
U722_RS11105	COG0667	Aldo Keto reductase
U722_RS11115	COG1073	alpha beta
U722_RS11125	COG4918	Iron-sulphur cluster biosynthesis
U722_RS11130	COG0456	acetyltransferase
U722_RS11130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
U722_RS11135	COG2329	Antibiotic biosynthesis monooxygenase
U722_RS11140	COG0456	acetyltransferase
U722_RS11145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
U722_RS11160	COG0628	permease
U722_RS11165	COG0346	lactoylglutathione lyase activity
U722_RS11175	COG3048	D-serine ammonia-lyase activity
U722_RS11180	COG0300	oxidoreductase activity
U722_RS11185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS11190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
U722_RS11195	COG1024	Enoyl-CoA hydratase
U722_RS11200	COG3425	synthase
U722_RS11205	COG2124	cytochrome p450
U722_RS11210	COG3321	synthase
U722_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11215	COG3321	synthase
U722_RS11215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11220	COG0300	oxidoreductase activity
U722_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS11220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11220	COG3321	synthase
U722_RS11225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11225	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS11225	COG0300	oxidoreductase activity
U722_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11225	COG3321	synthase
U722_RS11230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11230	COG0300	oxidoreductase activity
U722_RS11230	COG3321	synthase
U722_RS11230	COG4221	oxidoreductase activity
U722_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS11235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11235	COG3321	synthase
U722_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS11240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11240	COG3321	synthase
U722_RS11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11245	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS11245	COG0300	oxidoreductase activity
U722_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11245	COG3321	synthase
U722_RS11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
U722_RS11250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS11250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS11250	COG3321	synthase
U722_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS11260	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS11275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U722_RS11275	COG2070	2-Nitropropane dioxygenase
U722_RS11280	COG0250	Participates in transcription elongation, termination and antitermination
U722_RS11300	COG0596	Alpha beta hydrolase
U722_RS11310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
U722_RS11315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
U722_RS11330	COG0706	membrane insertase activity
U722_RS11335	COG2195	Cleaves the N-terminal amino acid of tripeptides
U722_RS11340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U722_RS11345	COG0346	lactoylglutathione lyase activity
U722_RS11350	COG1376	ErfK ybiS ycfS ynhG family protein
U722_RS11355	COG4129	membrane
U722_RS11360	COG1126	abc transporter atp-binding protein
U722_RS11365	COG0765	amino acid transport
U722_RS11370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS11380	COG1597	lipid kinase activity
U722_RS11385	COG0508	dehydrogenase complex catalyzes the overall conversion of
U722_RS11390	COG0022	dehydrogenase e1 component
U722_RS11395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U722_RS11400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
U722_RS11405	COG3426	butyrate kinase activity
U722_RS11410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_RS11415	COG0280	phosphate acetyltransferase
U722_RS11420	COG3829	transcription factor binding
U722_RS11420	COG3290	protein histidine kinase activity
U722_RS11430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
U722_RS11435	COG2079	MmgE PrpD family protein
U722_RS11440	COG0372	Belongs to the citrate synthase family
U722_RS11445	COG1960	acyl-CoA dehydrogenase activity
U722_RS11450	COG1250	3-hydroxyacyl-CoA dehydrogenase
U722_RS11455	COG0183	Belongs to the thiolase family
U722_RS11460	COG0584	glycerophosphoryl diester phosphodiesterase
U722_RS11465	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS11490	COG1902	pentaerythritol trinitrate reductase activity
U722_RS11505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
U722_RS11510	COG0745	RESPONSE REGULATOR receiver
U722_RS11515	COG0750	zinc metalloprotease
U722_RS11520	COG0497	DNA recombination
U722_RS11530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
U722_RS11540	COG0142	geranyltranstransferase activity
U722_RS11550	COG1570	exodeoxyribonuclease VII activity
U722_RS11565	COG1302	Protein conserved in bacteria
U722_RS11570	COG0439	Biotin carboxylase
U722_RS11575	COG0511	ligase activity, forming carbon-carbon bonds
U722_RS11615	COG3854	ATPases associated with a variety of cellular activities
U722_RS11630	COG0006	proline dipeptidase activity
U722_RS11640	COG3872	metal-dependent enzyme
U722_RS11650	COG1752	Esterase of the alpha-beta hydrolase superfamily
U722_RS11665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_RS11685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U722_RS11700	COG1396	sequence-specific DNA binding
U722_RS11710	COG0681	Belongs to the peptidase S26 family
U722_RS11735	COG4940	Competence protein ComGF
U722_RS11745	COG4970	Tfp pilus assembly protein FimT
U722_RS11750	COG4537	Required for transformation and DNA binding
U722_RS11755	COG1459	type II secretion system
U722_RS11760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U722_RS11765	COG0598	Magnesium transport protein CorA
U722_RS11770	COG1253	flavin adenine dinucleotide binding
U722_RS11775	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS11785	COG1393	Belongs to the ArsC family
U722_RS11795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS11805	COG0011	TIGRFAM Protein of
U722_RS11815	COG2866	Carboxypeptidase
U722_RS11820	COG1940	carbohydrate kinase activity
U722_RS11825	COG4483	Protein conserved in bacteria
U722_RS11830	COG1757	Na H antiporter
U722_RS11835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
U722_RS11845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U722_RS11850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_RS11855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
U722_RS11860	COG0581	inorganic phosphate transmembrane transporter activity
U722_RS11865	COG0573	inorganic phosphate transmembrane transporter activity
U722_RS11870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
U722_RS11875	COG0768	penicillin binding
U722_RS11880	COG0477	Major facilitator Superfamily
U722_RS11885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
U722_RS11890	COG2839	Protein conserved in bacteria
U722_RS11895	COG5521	maltodextrose utilization protein MalA
U722_RS11900	COG1388	LysM domain
U722_RS11910	COG4709	membrane
U722_RS11915	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
U722_RS11920	COG0735	belongs to the Fur family
U722_RS11925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS11940	COG0513	Belongs to the DEAD box helicase family
U722_RS11955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
U722_RS11960	COG2384	SAM-dependent methyltransferase
U722_RS11965	COG2010	Cytochrome c
U722_RS11970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
U722_RS11975	COG0358	DNA primase activity
U722_RS11990	COG0517	IMP dehydrogenase activity
U722_RS11995	COG0751	glycine-tRNA ligase activity
U722_RS12010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
U722_RS12015	COG0295	cytidine deaminase activity
U722_RS12020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
U722_RS12030	COG1480	7TM receptor with intracellular HD hydrolase
U722_RS12035	COG1702	phosphate starvation-inducible protein PhoH
U722_RS12040	COG0561	phosphatase activity
U722_RS12055	COG4864	UPF0365 protein
U722_RS12060	COG1030	water channel activity
U722_RS12065	COG1610	YqeY-like protein
U722_RS12075	COG1283	sodium-dependent phosphate transmembrane transporter activity
U722_RS12080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
U722_RS12085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
U722_RS12115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U722_RS12130	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS12145	COG1466	dna polymerase III delta subunit
U722_RS12155	COG2333	competence protein COMEC
U722_RS12155	COG0658	competence protein
U722_RS12160	COG2131	deaminase
U722_RS12165	COG1555	photosystem II stabilization
U722_RS12165	COG1596	polysaccharide export
U722_RS12170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
U722_RS12175	COG2226	methyltransferase
U722_RS12180	COG0799	negative regulation of ribosome biogenesis
U722_RS12185	COG1713	HD superfamily hydrolase involved in NAD metabolism
U722_RS12195	COG1534	Rna-binding protein
U722_RS12200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
U722_RS12205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
U722_RS12210	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
U722_RS12220	COG2755	lipolytic protein G-D-S-L family
U722_RS12230	COG0398	Pfam SNARE associated Golgi protein
U722_RS12255	COG3708	Transcriptional regulator
U722_RS12255	COG2207	Transcriptional regulator
U722_RS12265	COG0563	adenylate kinase activity
U722_RS12275	COG2814	Major facilitator Superfamily
U722_RS12280	COG0456	acetyltransferase
U722_RS12285	COG2318	DinB family
U722_RS12295	COG0561	phosphatase activity
U722_RS12300	COG0561	phosphatase activity
U722_RS12310	COG1482	cell wall glycoprotein biosynthetic process
U722_RS12315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS12315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_RS12315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U722_RS12320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS12320	COG3711	transcriptional antiterminator
U722_RS12330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U722_RS12335	COG0583	DNA-binding transcription factor activity
U722_RS12340	COG2814	Major facilitator Superfamily
U722_RS12345	COG2124	cytochrome p450
U722_RS12345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_RS12350	COG1309	transcriptional regulator
U722_RS12355	COG2226	methyltransferase
U722_RS12365	COG2116	formate transmembrane transporter activity
U722_RS12370	COG5609	conserved protein (DUF2294)
U722_RS12375	COG3383	formate dehydrogenase (NAD+) activity
U722_RS12380	COG2427	Protein of unknown function (DUF1641)
U722_RS12390	COG0626	cystathionine gamma-synthase activity
U722_RS12395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_RS12420	COG0768	penicillin binding
U722_RS12435	COG0826	peptidase U32
U722_RS12440	COG0826	peptidase U32
U722_RS12445	COG4122	O-methyltransferase activity
U722_RS12450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U722_RS12465	COG4472	Bacterial protein of unknown function (DUF965)
U722_RS12475	COG0628	permease
U722_RS12480	COG1126	abc transporter atp-binding protein
U722_RS12485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS12490	COG0765	amino acid transport
U722_RS12495	COG0765	amino acid transport
U722_RS12505	COG3881	PFAM PRC-barrel domain
U722_RS12510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
U722_RS12515	COG0457	Tetratricopeptide repeat
U722_RS12525	COG1104	cysteine desulfurase activity
U722_RS12530	COG1959	2 iron, 2 sulfur cluster binding
U722_RS12535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
U722_RS12540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
U722_RS12555	COG3103	Sh3 type 3 domain protein
U722_RS12555	COG4991	sh3 domain protein
U722_RS12555	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS12565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U722_RS12575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
U722_RS12575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
U722_RS12580	COG5416	Lipopolysaccharide assembly protein A domain
U722_RS12585	COG0490	domain, Protein
U722_RS12590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U722_RS12590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
U722_RS12600	COG2244	polysaccharide biosynthetic process
U722_RS12605	COG2323	membrane
U722_RS12615	COG1862	Preprotein translocase
U722_RS12660	COG1388	LysM domain
U722_RS12670	COG0157	Belongs to the NadC ModD family
U722_RS12675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
U722_RS12680	COG1104	cysteine desulfurase activity
U722_RS12685	COG1827	regulation of RNA biosynthetic process
U722_RS12690	COG0077	Prephenate dehydratase
U722_RS12705	COG3290	protein histidine kinase activity
U722_RS12710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
U722_RS12715	COG2868	ribosomal protein
U722_RS12725	COG1994	Peptidase M50
U722_RS12730	COG0739	heme binding
U722_RS12735	COG2894	cell division
U722_RS12745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
U722_RS12755	COG1077	Cell shape determining protein MreB Mrl
U722_RS12775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
U722_RS12780	COG0285	dihydrofolate synthase activity
U722_RS12785	COG0525	valine-tRNA ligase activity
U722_RS12795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_RS12800	COG1388	LysM domain
U722_RS12810	COG0113	porphobilinogen synthase activity
U722_RS12815	COG1587	Uroporphyrinogen-III synthase
U722_RS12825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
U722_RS12845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
U722_RS12850	COG1067	ATP-dependent peptidase activity
U722_RS12850	COG0470	DNA polymerase III
U722_RS12865	COG1477	protein flavinylation
U722_RS12865	COG0457	Tetratricopeptide repeat
U722_RS12880	COG0473	3-isopropylmalate dehydrogenase activity
U722_RS12895	COG0440	acetolactate synthase activity
U722_RS12900	COG0028	Belongs to the TPP enzyme family
U722_RS12925	COG0622	Phosphoesterase
U722_RS12930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
U722_RS12940	COG5401	PFAM Sporulation and spore germination
U722_RS12950	COG1846	Transcriptional regulator
U722_RS12955	COG2197	response regulator
U722_RS12960	COG0824	Thioesterase
U722_RS12965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
U722_RS12970	COG1053	succinate dehydrogenase
U722_RS12975	COG2009	succinate dehydrogenase
U722_RS12980	COG1719	4-vinyl reductase, 4VR
U722_RS12985	COG0527	aspartate kinase activity
U722_RS12995	COG3118	belongs to the thioredoxin family
U722_RS13000	COG3534	alpha-L-arabinofuranosidase
U722_RS13005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
U722_RS13010	COG2086	electron transfer activity
U722_RS13015	COG1024	Enoyl-CoA hydratase
U722_RS13020	COG1309	transcriptional regulator
U722_RS13025	COG0318	PFAM AMP-dependent synthetase and ligase
U722_RS13035	COG3766	membrane
U722_RS13045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
U722_RS13045	COG1796	DNA polymerase
U722_RS13050	COG1286	toxin biosynthetic process
U722_RS13065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_RS13065	COG0072	phenylalanine-tRNA ligase activity
U722_RS13070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
U722_RS13075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
U722_RS13085	COG3835	regulator
U722_RS13090	COG0277	FAD linked oxidase domain protein
U722_RS13095	COG0247	lactate metabolic process
U722_RS13100	COG1966	Carbon starvation protein
U722_RS13105	COG3534	alpha-L-arabinofuranosidase
U722_RS13110	COG0395	ABC-type sugar transport system, permease component
U722_RS13115	COG1175	transmembrane transport
U722_RS13120	COG1653	transport
U722_RS13130	COG0647	UMP catabolic process
U722_RS13135	COG0235	Class ii aldolase
U722_RS13140	COG1069	ribulokinase activity
U722_RS13145	COG2160	L-arabinose isomerase activity
U722_RS13150	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_RS13155	COG1363	Peptidase, m42
U722_RS13165	COG3326	Membrane
U722_RS13170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
U722_RS13180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
U722_RS13185	COG1346	cytolysis
U722_RS13190	COG1380	Effector of murein hydrolase LrgA
U722_RS13195	COG3279	Response regulator of the LytR AlgR family
U722_RS13200	COG3275	phosphorelay sensor kinase activity
U722_RS13205	COG1011	Hydrolase
U722_RS13220	COG0398	Pfam SNARE associated Golgi protein
U722_RS13225	COG1484	DNA-dependent DNA replication
U722_RS13230	COG3611	Membrane attachment protein
U722_RS13245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U722_RS13250	COG1733	regulation of RNA biosynthetic process
U722_RS13255	COG2814	Major facilitator Superfamily
U722_RS13260	COG0656	L-ascorbic acid biosynthetic process
U722_RS13265	COG0237	dephospho-CoA kinase activity
U722_RS13270	COG1971	Probably functions as a manganese efflux pump
U722_RS13275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
U722_RS13280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_RS13280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
U722_RS13285	COG5002	protein histidine kinase activity
U722_RS13290	COG0745	RESPONSE REGULATOR receiver
U722_RS13300	COG0538	isocitrate dehydrogenase activity
U722_RS13305	COG0372	Belongs to the citrate synthase family
U722_RS13320	COG0628	permease
U722_RS13325	COG3030	protein affecting phage T7 exclusion by the F plasmid
U722_RS13330	COG0469	pyruvate kinase activity
U722_RS13355	COG0281	malic enzyme
U722_RS13360	COG0587	DNA-directed DNA polymerase activity
U722_RS13380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
U722_RS13390	COG4109	DRTGG domain
U722_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS13415	COG0521	Mo-molybdopterin cofactor biosynthetic process
U722_RS13425	COG0827	DNA restriction-modification system
U722_RS13430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
U722_RS13435	COG3874	Sporulation protein YtfJ
U722_RS13445	COG1714	RDD family
U722_RS13450	COG0616	signal peptide processing
U722_RS13455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
U722_RS13460	COG1574	metal-dependent hydrolase with the TIM-barrel fold
U722_RS13465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U722_RS13480	COG1104	cysteine desulfurase activity
U722_RS13485	COG1114	Component of the transport system for branched-chain amino acids
U722_RS13495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
U722_RS13500	COG1309	transcriptional regulator
U722_RS13505	COG1956	GAF domain-containing protein
U722_RS13510	COG2199	diguanylate cyclase activity
U722_RS13510	COG2203	Gaf domain
U722_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS13530	COG4282	regulation of fungal-type cell wall biogenesis
U722_RS13535	COG1017	nitric oxide dioxygenase activity
U722_RS13535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U722_RS13545	COG0693	protein deglycase activity
U722_RS13560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U722_RS13565	COG1378	Sugar-specific transcriptional regulator TrmB
U722_RS13585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U722_RS13590	COG0454	-acetyltransferase
U722_RS13595	COG0517	IMP dehydrogenase activity
U722_RS13600	COG0123	including yeast histone deacetylase and acetoin utilization protein
U722_RS13605	COG1360	Flagellar Motor Protein
U722_RS13610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U722_RS13615	COG1609	Transcriptional regulator
U722_RS13620	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
U722_RS13620	COG1605	Chorismate mutase
U722_RS13625	COG3118	belongs to the thioredoxin family
U722_RS13630	COG4980	gas vesicle protein
U722_RS13635	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
U722_RS13645	COG1674	ftsk spoiiie
U722_RS13650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U722_RS13660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS13670	COG1363	Peptidase, m42
U722_RS13675	COG5584	Small secreted protein
U722_RS13680	COG0281	malic enzyme
U722_RS13685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U722_RS13700	COG0510	thiamine kinase activity
U722_RS13705	COG1597	lipid kinase activity
U722_RS13715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
U722_RS13720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U722_RS13725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_RS13730	COG2252	PERMEase
U722_RS13735	COG4473	ABC transporter
U722_RS13740	COG1131	(ABC) transporter
U722_RS13745	COG1187	pseudouridine synthase activity
U722_RS13750	COG2244	polysaccharide biosynthetic process
U722_RS13755	COG2081	HI0933 family
U722_RS13760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U722_RS13770	COG1609	Transcriptional regulator
U722_RS13775	COG1653	transport
U722_RS13780	COG1175	transmembrane transport
U722_RS13785	COG0395	ABC-type sugar transport system, permease component
U722_RS13790	COG1486	melibiose metabolic process
U722_RS13800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
U722_RS13815	COG2202	Pas domain
U722_RS13815	COG1366	Belongs to the anti-sigma-factor antagonist family
U722_RS13820	COG2814	Major facilitator Superfamily
U722_RS13825	COG5522	Integral membrane protein (intg_mem_TP0381)
U722_RS13830	COG0577	efflux transmembrane transporter activity
U722_RS13835	COG1136	(ABC) transporter
U722_RS13840	COG2205	protein histidine kinase activity
U722_RS13845	COG0745	RESPONSE REGULATOR receiver
U722_RS13850	COG0577	efflux transmembrane transporter activity
U722_RS13855	COG1136	(ABC) transporter
U722_RS13875	COG1131	(ABC) transporter
U722_RS13880	COG1725	Transcriptional regulator
U722_RS13890	COG0640	Transcriptional regulator
U722_RS13895	COG0477	Major facilitator Superfamily
U722_RS13900	COG1242	4 iron, 4 sulfur cluster binding
U722_RS13905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
U722_RS13915	COG0584	glycerophosphoryl diester phosphodiesterase
U722_RS13925	COG2267	carboxylic ester hydrolase activity
U722_RS13930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U722_RS13935	COG1113	amino acid transport
U722_RS13940	COG0367	asparagine synthase
U722_RS13960	COG1506	peptidase
U722_RS13965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U722_RS13970	COG1116	anion transmembrane transporter activity
U722_RS13975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U722_RS13980	COG0494	nUDIX hydrolase
U722_RS13985	COG4824	toxin secretion phage lysis holin
U722_RS13990	COG0783	Belongs to the Dps family
U722_RS14015	COG0288	reversible hydration of carbon dioxide
U722_RS14025	COG1271	oxidase subunit
U722_RS14030	COG1294	oxidase, subunit
U722_RS14035	COG4948	Mandelate Racemase Muconate Lactonizing
U722_RS14045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
U722_RS14050	COG0596	Alpha beta hydrolase
U722_RS14060	COG1169	isochorismate synthase
U722_RS14065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U722_RS14070	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
U722_RS14205	COG3859	Proton-coupled thiamine transporter YuaJ
U722_RS14210	COG2268	Band 7 protein
U722_RS14215	COG1585	Membrane protein implicated in regulation of membrane protease activity
U722_RS14220	COG2318	DinB family
U722_RS14230	COG1454	alcohol dehydrogenase
U722_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS14240	COG1510	regulation of RNA biosynthetic process
U722_RS14250	COG0569	domain protein
U722_RS14255	COG1705	Flagellar rod assembly protein muramidase FlgJ
U722_RS14260	COG1017	nitric oxide dioxygenase activity
U722_RS14260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U722_RS14285	COG0628	permease
U722_RS14290	COG0673	inositol 2-dehydrogenase activity
U722_RS14295	COG0693	protein deglycase activity
U722_RS14300	COG0840	transmembrane signaling receptor activity
U722_RS14305	COG0840	transmembrane signaling receptor activity
U722_RS14310	COG0840	transmembrane signaling receptor activity
U722_RS14315	COG0840	transmembrane signaling receptor activity
U722_RS14330	COG2070	2-Nitropropane dioxygenase
U722_RS14335	COG0432	Pfam Uncharacterised protein family UPF0047
U722_RS14340	COG0366	Alpha amylase catalytic
U722_RS14345	COG1253	flavin adenine dinucleotide binding
U722_RS14350	COG2738	Putative neutral zinc metallopeptidase
U722_RS14365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U722_RS14390	COG1335	isochorismatase
U722_RS14395	COG1979	alcohol dehydrogenase
U722_RS14400	COG1979	alcohol dehydrogenase
U722_RS14405	COG2155	Conserved Protein
U722_RS14410	COG1098	S1 RNA binding domain
U722_RS14415	COG0436	Aminotransferase
U722_RS14420	COG1522	sequence-specific DNA binding
U722_RS14425	COG2267	carboxylic ester hydrolase activity
U722_RS14435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
U722_RS14440	COG2205	protein histidine kinase activity
U722_RS14450	COG5018	Exonuclease
U722_RS14455	COG2814	Major facilitator Superfamily
U722_RS14460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_RS14465	COG3011	Protein conserved in bacteria
U722_RS14475	COG3290	protein histidine kinase activity
U722_RS14480	COG4565	transcriptional regulatory protein
U722_RS14485	COG1744	ABC transporter substrate-binding protein PnrA-like
U722_RS14490	COG3845	ABC transporter
U722_RS14495	COG4603	Belongs to the binding-protein-dependent transport system permease family
U722_RS14500	COG1079	Belongs to the binding-protein-dependent transport system permease family
U722_RS14510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
U722_RS14510	COG2111	Na H antiporter
U722_RS14515	COG2111	Na H antiporter
U722_RS14520	COG1006	Multisubunit Na H antiporter MnhC subunit
U722_RS14525	COG0651	ATP synthesis coupled electron transport
U722_RS14530	COG1863	multisubunit Na H antiporter MnhE subunit
U722_RS14535	COG2212	antiporter activity
U722_RS14540	COG1320	monovalent cation:proton antiporter activity
U722_RS14545	COG2050	protein possibly involved in aromatic compounds catabolism
U722_RS14550	COG2197	response regulator
U722_RS14555	COG4585	Histidine kinase
U722_RS14565	COG0142	geranyltranstransferase activity
U722_RS14580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
U722_RS14585	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
U722_RS14590	COG1335	isochorismatase
U722_RS14595	COG5506	Protein of unknown function (DUF1694)
U722_RS14610	COG0628	permease
U722_RS14620	COG1418	mRNA catabolic process
U722_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS14635	COG1511	domain protein
U722_RS14640	COG0433	COG0433 Predicted ATPase
U722_RS14640	COG1674	ftsk spoiiie
U722_RS14645	COG4499	WXG100 protein secretion system (Wss), protein YukC
U722_RS14650	COG5417	Belongs to the EsaB family
U722_RS14655	COG4842	Belongs to the WXG100 family
U722_RS14660	COG2508	Transcriptional regulator
U722_RS14660	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
U722_RS14665	COG0686	Belongs to the AlaDH PNT family
U722_RS14670	COG5634	Uncharacterized conserved protein (DUF2278)
U722_RS14675	COG3251	PFAM MbtH domain protein
U722_RS14680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U722_RS14685	COG3433	isochorismatase activity
U722_RS14685	COG1535	isochorismatase
U722_RS14690	COG1021	2,3-dihydroxybenzoate-AMP ligase
U722_RS14695	COG1169	isochorismate synthase
U722_RS14700	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS14705	COG2819	hydrolase of the alpha beta superfamily
U722_RS14710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
U722_RS14715	COG1268	BioY protein
U722_RS14720	COG2056	Na+-H+ antiporter family
U722_RS14730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
U722_RS14735	COG3584	3D domain protein
U722_RS14745	COG1252	NADH dehydrogenase
U722_RS14770	COG1131	(ABC) transporter
U722_RS14795	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
U722_RS14800	COG0316	Belongs to the HesB IscA family
U722_RS14810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_RS14820	COG1252	NADH dehydrogenase
U722_RS14825	COG4837	Protein of unknown function (DUF1462)
U722_RS14830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
U722_RS14835	COG1506	peptidase
U722_RS14835	COG0823	Involved in the tonB-independent uptake of proteins
U722_RS14835	COG4946	Tricorn protease homolog
U722_RS14845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
U722_RS14850	COG0460	homoserine dehydrogenase
U722_RS14855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
U722_RS14860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
U722_RS14865	COG0647	UMP catabolic process
U722_RS14870	COG2445	Protein of unknown function DUF86
U722_RS14875	COG4470	Protein conserved in bacteria
U722_RS14885	COG0739	heme binding
U722_RS14895	COG0737	Belongs to the 5'-nucleotidase family
U722_RS14900	COG0730	response to heat
U722_RS14905	COG1801	Protein of unknown function DUF72
U722_RS14920	COG2508	Transcriptional regulator
U722_RS14925	COG0338	D12 class N6 adenine-specific DNA methyltransferase
U722_RS14940	COG2814	Major facilitator Superfamily
U722_RS14945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
U722_RS14950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
U722_RS14955	COG2356	endonuclease I
U722_RS14960	COG3842	ATPase activity
U722_RS14965	COG2188	Transcriptional regulator
U722_RS14970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_RS14975	COG0395	ABC-type sugar transport system, permease component
U722_RS14980	COG1175	transmembrane transport
U722_RS14985	COG1653	transport
U722_RS14990	COG2222	sugar isomerase
U722_RS14995	COG0789	Transcriptional regulator
U722_RS15005	COG0322	excinuclease ABC activity
U722_RS15010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U722_RS15015	COG2226	methyltransferase
U722_RS15025	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS15030	COG0719	Fe-S assembly protein
U722_RS15035	COG0822	iron-sulfur transferase activity
U722_RS15040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U722_RS15045	COG0719	Fe-S assembly protein
U722_RS15050	COG0396	ATPase activity
U722_RS15055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U722_RS15060	COG1464	Belongs to the NlpA lipoprotein family
U722_RS15065	COG2011	ABC-type metal ion transport system permease component
U722_RS15070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
U722_RS15080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
U722_RS15085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
U722_RS15100	COG1393	Belongs to the ArsC family
U722_RS15105	COG1960	acyl-CoA dehydrogenase activity
U722_RS15110	COG0183	Belongs to the thiolase family
U722_RS15115	COG1250	3-hydroxyacyl-CoA dehydrogenase
U722_RS15115	COG1024	Enoyl-CoA hydratase
U722_RS15130	COG0477	Major facilitator Superfamily
U722_RS15140	COG5577	PFAM Coat F domain
U722_RS15145	COG1846	Transcriptional regulator
U722_RS15150	COG0477	Major facilitator Superfamily
U722_RS15155	COG0583	DNA-binding transcription factor activity
U722_RS15175	COG1120	ATPase activity
U722_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS15195	COG0783	Belongs to the Dps family
U722_RS15200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_RS15205	COG0745	RESPONSE REGULATOR receiver
U722_RS15210	COG2770	Histidine kinase
U722_RS15210	COG2205	protein histidine kinase activity
U722_RS15215	COG1309	transcriptional regulator
U722_RS15220	COG0114	fumarate hydratase activity
U722_RS15230	COG0697	spore germination
U722_RS15235	COG0814	amino acid
U722_RS15245	COG2197	response regulator
U722_RS15250	COG4585	Histidine kinase
U722_RS15255	COG4758	membrane
U722_RS15260	COG3595	metallopeptidase activity
U722_RS15265	COG1842	Phage shock protein A
U722_RS15270	COG4758	membrane
U722_RS15275	COG2814	Major facilitator Superfamily
U722_RS15280	COG2096	Adenosyltransferase
U722_RS15285	COG1120	ATPase activity
U722_RS15290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS15295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_RS15300	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS15305	COG3386	PFAM SMP-30 Gluconolaconase
U722_RS15310	COG2205	protein histidine kinase activity
U722_RS15315	COG0745	RESPONSE REGULATOR receiver
U722_RS15325	COG1191	sigma factor activity
U722_RS15330	COG2140	Oxalate decarboxylase
U722_RS15340	COG1120	ATPase activity
U722_RS15345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS15350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS15355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_RS15360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
U722_RS15365	COG0531	amino acid
U722_RS15375	COG1988	membrane-bound metal-dependent
U722_RS15380	COG1368	sulfuric ester hydrolase activity
U722_RS15385	COG1910	domain protein
U722_RS15390	COG0725	ABC transporter, periplasmic molybdate-binding protein
U722_RS15395	COG4149	molybdate abc transporter
U722_RS15400	COG2197	response regulator
U722_RS15405	COG3850	Histidine kinase
U722_RS15410	COG1131	(ABC) transporter
U722_RS15420	COG0842	Transport permease protein
U722_RS15425	COG0656	L-ascorbic acid biosynthetic process
U722_RS15450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U722_RS15455	COG3973	AAA domain
U722_RS15460	COG2860	membrane
U722_RS15470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
U722_RS15475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U722_RS15480	COG2217	Heavy metal translocating P-type atpase
U722_RS15485	COG2217	Heavy metal translocating P-type atpase
U722_RS15490	COG2608	mercury ion transmembrane transporter activity
U722_RS15495	COG1937	Protein conserved in bacteria
U722_RS15500	COG0673	inositol 2-dehydrogenase activity
U722_RS15515	COG2814	Major facilitator Superfamily
U722_RS15530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS15535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
U722_RS15540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS15545	COG1126	abc transporter atp-binding protein
U722_RS15550	COG0765	amino acid transport
U722_RS15555	COG0765	amino acid transport
U722_RS15560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS15565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U722_RS15570	COG0454	-acetyltransferase
U722_RS15575	COG0583	DNA-binding transcription factor activity
U722_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS15585	COG2732	(Barnase) inhibitor
U722_RS15595	COG0557	exoribonuclease II activity
U722_RS15600	COG1647	Serine aminopeptidase, S33
U722_RS15605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
U722_RS15610	COG1476	TRANSCRIPTIONal
U722_RS15615	COG1396	sequence-specific DNA binding
U722_RS15620	COG1396	sequence-specific DNA binding
U722_RS15625	COG1733	regulation of RNA biosynthetic process
U722_RS15650	COG1131	(ABC) transporter
U722_RS15655	COG1174	glycine betaine transport
U722_RS15660	COG1732	Glycine betaine
U722_RS15665	COG1174	glycine betaine transport
U722_RS15670	COG1125	glycine betaine transport
U722_RS15670	COG0517	IMP dehydrogenase activity
U722_RS15675	COG1510	regulation of RNA biosynthetic process
U722_RS15680	COG1174	glycine betaine transport
U722_RS15685	COG1732	Glycine betaine
U722_RS15690	COG1174	glycine betaine transport
U722_RS15695	COG1125	glycine betaine transport
U722_RS15695	COG0517	IMP dehydrogenase activity
U722_RS15700	COG1510	regulation of RNA biosynthetic process
U722_RS15705	COG2095	MarC family integral membrane protein
U722_RS15710	COG3064	Membrane
U722_RS15715	COG4640	response to antibiotic
U722_RS15720	COG0456	acetyltransferase
U722_RS15735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
U722_RS15750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_RS15755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U722_RS15760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_RS15770	COG2234	aminopeptidase activity
U722_RS15790	COG0126	phosphoglycerate kinase activity
U722_RS15800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U722_RS15805	COG2390	Transcriptional regulator
U722_RS15810	COG2814	Major facilitator Superfamily
U722_RS15815	COG1609	Transcriptional regulator
U722_RS15820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS15830	COG0583	DNA-binding transcription factor activity
U722_RS15835	COG0697	spore germination
U722_RS15840	COG1113	amino acid transport
U722_RS15845	COG1737	Transcriptional regulator
U722_RS15850	COG1070	Carbohydrate kinase
U722_RS15875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_RS15880	COG2186	Transcriptional regulator
U722_RS15885	COG1620	l-lactate permease
U722_RS15890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
U722_RS15900	COG5039	Polysaccharide pyruvyl transferase
U722_RS15905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_RS15910	COG0110	maltose O-acetyltransferase activity
U722_RS15915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
U722_RS15920	COG2244	polysaccharide biosynthetic process
U722_RS15925	COG1216	Glycosyl transferase, family 2
U722_RS15930	COG5039	Polysaccharide pyruvyl transferase
U722_RS15935	COG1216	Glycosyl transferase, family 2
U722_RS15945	COG0438	transferase activity, transferring glycosyl groups
U722_RS15950	COG1215	transferase activity, transferring glycosyl groups
U722_RS15955	COG0438	transferase activity, transferring glycosyl groups
U722_RS15960	COG1086	Polysaccharide biosynthesis protein
U722_RS15965	COG0489	protein tyrosine kinase activity
U722_RS15970	COG3944	biosynthesis protein
U722_RS15975	COG1396	sequence-specific DNA binding
U722_RS15980	COG2272	Belongs to the type-B carboxylesterase lipase family
U722_RS15990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U722_RS15995	COG2364	Membrane
U722_RS16000	COG0456	acetyltransferase
U722_RS16005	COG3479	Phenolic acid decarboxylase
U722_RS16055	COG2223	nitrite transmembrane transporter activity
U722_RS16060	COG1609	Transcriptional regulator
U722_RS16070	COG0583	DNA-binding transcription factor activity
U722_RS16075	COG2828	Protein conserved in bacteria
U722_RS16080	COG2814	Major facilitator Superfamily
U722_RS16080	COG0477	Major facilitator Superfamily
U722_RS16085	COG1611	Belongs to the LOG family
U722_RS16090	COG1694	Mazg nucleotide pyrophosphohydrolase
U722_RS16095	COG0659	secondary active sulfate transmembrane transporter activity
U722_RS16100	COG0288	reversible hydration of carbon dioxide
U722_RS16110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U722_RS16115	COG4290	ribonuclease
U722_RS16120	COG2162	N-hydroxyarylamine O-acetyltransferase activity
U722_RS16125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS16135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
U722_RS16145	COG1051	belongs to the nudix hydrolase family
U722_RS16150	COG0492	ferredoxin-NADP+ reductase activity
U722_RS16155	COG3883	PFAM NLP P60 protein
U722_RS16155	COG0791	NLP P60 protein
U722_RS16160	COG0457	Tetratricopeptide repeat
U722_RS16165	COG5002	protein histidine kinase activity
U722_RS16170	COG0745	RESPONSE REGULATOR receiver
U722_RS16180	COG1132	(ABC) transporter
U722_RS16185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
U722_RS16185	COG0140	phosphoribosyl-ATP diphosphatase activity
U722_RS16210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
U722_RS16225	COG4990	cell redox homeostasis
U722_RS16230	COG0110	maltose O-acetyltransferase activity
U722_RS16250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U722_RS16260	COG2188	Transcriptional regulator
U722_RS16265	COG1309	transcriptional regulator
U722_RS16270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
U722_RS16275	COG1950	PFAM Membrane protein of
U722_RS16280	COG1983	PspC domain protein
U722_RS16285	COG3595	metallopeptidase activity
U722_RS16300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
U722_RS16310	COG4897	Protein conserved in bacteria
U722_RS16315	COG0574	Belongs to the PEP-utilizing enzyme family
U722_RS16315	COG3848	Pyruvate phosphate dikinase
U722_RS16320	COG1309	transcriptional regulator
U722_RS16325	COG2814	Major facilitator Superfamily
U722_RS16335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_RS16345	COG3409	Peptidoglycan-binding domain 1 protein
U722_RS16345	COG0793	Belongs to the peptidase S41A family
U722_RS16350	COG3420	alginic acid biosynthetic process
U722_RS16355	COG2177	Part of the ABC transporter FtsEX involved in
U722_RS16360	COG2884	Cell division ATP-binding protein ftsE
U722_RS16365	COG2010	Cytochrome c
U722_RS16370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS16375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U722_RS16385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
U722_RS16400	COG1516	flagellar protein fliS
U722_RS16405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
U722_RS16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U722_RS16430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U722_RS16435	COG1256	bacterial-type flagellum assembly
U722_RS16435	COG4786	Flagellar basal body rod
U722_RS16440	COG3418	PFAM FlgN family protein
U722_RS16445	COG2747	anti-sigma28 factor FlgM
U722_RS16455	COG1040	competence protein
U722_RS16465	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
U722_RS16470	COG1307	EDD domain protein, DegV family
U722_RS16475	COG2197	response regulator
U722_RS16480	COG4585	Histidine kinase
U722_RS16485	COG1739	Uncharacterized protein family UPF0029
U722_RS16490	COG1316	TRANSCRIPTIONal
U722_RS16495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
U722_RS16500	COG0438	transferase activity, transferring glycosyl groups
U722_RS16505	COG1215	transferase activity, transferring glycosyl groups
U722_RS16510	COG3206	protein involved in exopolysaccharide biosynthesis
U722_RS16515	COG3307	-O-antigen
U722_RS16520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
U722_RS16525	COG0438	transferase activity, transferring glycosyl groups
U722_RS16525	COG0297	glycogen (starch) synthase activity
U722_RS16530	COG2244	polysaccharide biosynthetic process
U722_RS16540	COG0860	N-Acetylmuramoyl-L-alanine amidase
U722_RS16540	COG2247	cell wall binding repeat
U722_RS16545	COG2247	cell wall binding repeat
U722_RS16545	COG2385	sporulation resulting in formation of a cellular spore
U722_RS16555	COG1316	TRANSCRIPTIONal
U722_RS16560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
U722_RS16565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
U722_RS16570	COG1134	teichoic acid transport
U722_RS16575	COG1682	transport, permease protein
U722_RS16580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_RS16590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
U722_RS16595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
U722_RS16600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_RS16605	COG4193	domain, Protein
U722_RS16610	COG1482	cell wall glycoprotein biosynthetic process
U722_RS16615	COG0697	spore germination
U722_RS16620	COG0814	amino acid
U722_RS16630	COG1215	transferase activity, transferring glycosyl groups
U722_RS16635	COG2814	Major facilitator Superfamily
U722_RS16640	COG1316	TRANSCRIPTIONal
U722_RS16645	COG0561	phosphatase activity
U722_RS16650	COG2433	Pfam Transposase IS66
U722_RS16655	COG0791	NLP P60 protein
U722_RS16660	COG2843	Capsule synthesis protein
U722_RS16670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
U722_RS16675	COG0697	spore germination
U722_RS16680	COG0814	amino acid
U722_RS16690	COG1609	Transcriptional regulator
U722_RS16695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U722_RS16705	COG1129	ABC transporter
U722_RS16710	COG1172	Belongs to the binding-protein-dependent transport system permease family
U722_RS16715	COG1879	ABC-type sugar transport system periplasmic component
U722_RS16720	COG3103	Sh3 type 3 domain protein
U722_RS16725	COG2249	NAD(P)H dehydrogenase (quinone) activity
U722_RS16730	COG3527	Alpha-acetolactate decarboxylase
U722_RS16735	COG0028	Belongs to the TPP enzyme family
U722_RS16740	COG0583	DNA-binding transcription factor activity
U722_RS16745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
U722_RS16760	COG5337	Spore coat protein CotH
U722_RS16770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
U722_RS16780	COG0405	Gamma-glutamyltransferase
U722_RS16785	COG1522	sequence-specific DNA binding
U722_RS16790	COG2059	Chromate
U722_RS16795	COG2059	Chromate
U722_RS16805	COG0655	NAD(P)H dehydrogenase (quinone) activity
U722_RS16810	COG0583	DNA-binding transcription factor activity
U722_RS16830	COG5444	nuclease activity
U722_RS16850	COG5444	nuclease activity
U722_RS16865	COG3878	Protein conserved in bacteria
U722_RS16870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
U722_RS16875	COG4464	protein tyrosine phosphatase activity
U722_RS16880	COG0489	protein tyrosine kinase activity
U722_RS16885	COG3944	biosynthesis protein
U722_RS16895	COG4715	Zinc finger, swim domain protein
U722_RS16900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U722_RS16905	COG0561	phosphatase activity
U722_RS16910	COG1349	DNA-binding transcription factor activity
U722_RS16915	COG0629	single-stranded DNA binding
U722_RS16940	COG0457	Tetratricopeptide repeat
U722_RS16945	COG4786	Flagellar basal body rod
U722_RS16950	COG4786	Flagellar basal body rod
U722_RS16955	COG1077	Cell shape determining protein MreB Mrl
U722_RS16960	COG1609	Transcriptional regulator
U722_RS16965	COG1846	Transcriptional regulator
U722_RS16970	COG2814	Major facilitator Superfamily
U722_RS16975	COG1953	Uracil, thiamine, allantoin
U722_RS16980	COG0477	Major facilitator Superfamily
U722_RS16985	COG1335	isochorismatase
U722_RS16990	COG0004	ammonium transporteR
U722_RS16995	COG0347	Belongs to the P(II) protein family
U722_RS17000	COG0772	Belongs to the SEDS family
U722_RS17005	COG0671	phosphoesterase, PA-phosphatase related
U722_RS17015	COG0739	heme binding
U722_RS17020	COG1247	-acetyltransferase
U722_RS17035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_RS17045	COG0726	polysaccharide deacetylase
U722_RS17055	COG1959	2 iron, 2 sulfur cluster binding
U722_RS17070	COG0831	urea catabolic process
U722_RS17075	COG3237	CsbD-like
U722_RS17080	COG1994	Peptidase M50
U722_RS17085	COG0457	Tetratricopeptide repeat
U722_RS17095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
U722_RS17100	COG2304	oxidoreductase activity
U722_RS17105	COG2304	oxidoreductase activity
U722_RS17110	COG2385	sporulation resulting in formation of a cellular spore
U722_RS17115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
U722_RS17125	COG4836	Membrane
U722_RS17195	COG0698	ribose 5-phosphate isomerase
U722_RS17200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U722_RS17210	COG0009	L-threonylcarbamoyladenylate synthase
U722_RS17215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
U722_RS17235	COG2890	protein-(glutamine-N5) methyltransferase activity
U722_RS17240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
U722_RS17245	COG0346	lactoylglutathione lyase activity
U722_RS17250	COG0789	Transcriptional regulator
U722_RS17255	COG0679	Auxin Efflux Carrier
U722_RS17260	COG0281	malic enzyme
U722_RS17275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
U722_RS17280	COG1494	fructose-1,6-bisphosphatase
U722_RS17285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
U722_RS17295	COG0191	fructose-bisphosphate aldolase activity
U722_RS17300	COG2204	response regulator
U722_RS17305	COG4821	SIS domain
U722_RS17320	COG2181	nitrate reductase activity
U722_RS17320	COG0247	lactate metabolic process
U722_RS17325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_RS17340	COG1132	(ABC) transporter
U722_RS17345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U722_RS17355	COG2181	nitrate reductase activity
U722_RS17360	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
U722_RS17365	COG1140	nitrate reductase beta subunit
U722_RS17370	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
U722_RS17375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_RS17385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U722_RS17390	COG2223	nitrite transmembrane transporter activity
U722_RS17400	COG4506	Protein conserved in bacteria
U722_RS17405	COG0457	Tetratricopeptide repeat
U722_RS17410	COG0010	Belongs to the arginase family
U722_RS17415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
U722_RS17420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U722_RS17435	COG1994	Peptidase M50
U722_RS17440	COG1942	4-Oxalocrotonate Tautomerase
U722_RS17445	COG1846	Transcriptional regulator
U722_RS17455	COG0531	amino acid
U722_RS17460	COG3465	dGTPase activity
U722_RS17465	COG1078	dGTPase activity
U722_RS17480	COG1695	Transcriptional regulator
U722_RS17495	COG0583	DNA-binding transcription factor activity
U722_RS17500	COG2855	membrane
U722_RS17505	COG0280	phosphate acetyltransferase
U722_RS17515	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS17520	COG0436	Aminotransferase
U722_RS17550	COG2814	Major facilitator Superfamily
U722_RS17555	COG2814	Major facilitator Superfamily
U722_RS17560	COG0833	amino acid
U722_RS17565	COG4187	Peptidase family M20/M25/M40
U722_RS17570	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS17575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U722_RS17585	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
U722_RS17590	COG1091	dTDP-4-dehydrorhamnose reductase activity
U722_RS17595	COG1088	dTDP-glucose 4,6-dehydratase activity
U722_RS17600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
U722_RS17605	COG3980	spore coat polysaccharide biosynthesis protein
U722_RS17610	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
U722_RS17615	COG2089	acid synthase
U722_RS17620	COG0456	acetyltransferase
U722_RS17625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
U722_RS17630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
U722_RS17635	COG0463	Glycosyl transferase, family 2
U722_RS17645	COG2363	Small membrane protein
U722_RS17650	COG2233	PERMEase
U722_RS17665	COG1216	Glycosyl transferase, family 2
U722_RS17680	COG1695	Transcriptional regulator
U722_RS17685	COG0351	phosphomethylpyrimidine kinase
U722_RS17695	COG1621	beta-fructofuranosidase activity
U722_RS17700	COG1263	PTS System
U722_RS17700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
U722_RS17705	COG3711	transcriptional antiterminator
U722_RS17715	COG1404	Belongs to the peptidase S8 family
U722_RS17720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U722_RS17725	COG0778	Nitroreductase
U722_RS17730	COG0772	Belongs to the SEDS family
U722_RS17735	COG0454	-acetyltransferase
U722_RS17755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U722_RS17760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U722_RS17765	COG2261	transglycosylase associated protein
U722_RS17770	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
U722_RS17775	COG2246	polysaccharide biosynthetic process
U722_RS17780	COG1309	transcriptional regulator
U722_RS17800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
U722_RS17805	COG2837	iron assimilation
U722_RS17825	COG0583	DNA-binding transcription factor activity
U722_RS17835	COG1346	cytolysis
U722_RS17840	COG4895	conserved protein (DUF2196)
U722_RS17845	COG0789	Transcriptional regulator
U722_RS17850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
U722_RS17855	COG0346	lactoylglutathione lyase activity
U722_RS17860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS17865	COG1404	Belongs to the peptidase S8 family
U722_RS17870	COG1442	glycosyl transferase family 8
U722_RS17875	COG2357	RelA SpoT domain protein
U722_RS17880	COG1575	Belongs to the MenA family. Type 1 subfamily
U722_RS17895	COG1696	Membrane protein involved in D-alanine export
U722_RS17905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
U722_RS17910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
U722_RS17915	COG1486	melibiose metabolic process
U722_RS17920	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_RS17925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS17930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS17935	COG3711	transcriptional antiterminator
U722_RS17935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
U722_RS17945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS17950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U722_RS17960	COG0640	Transcriptional regulator
U722_RS17965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
U722_RS17970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS17975	COG1447	Phosphotransferase system cellobiose-specific component IIA
U722_RS17980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
U722_RS17985	COG2723	6-phospho-beta-galactosidase activity
U722_RS17990	COG1940	carbohydrate kinase activity
U722_RS17995	COG1482	cell wall glycoprotein biosynthetic process
U722_RS18005	COG0753	catalase activity
U722_RS18010	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
U722_RS18015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U722_RS18020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
U722_RS18025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
U722_RS18030	COG4988	ABC transporter
U722_RS18035	COG1294	oxidase, subunit
U722_RS18040	COG1271	oxidase subunit
U722_RS18045	COG3493	citrate carrier protein
U722_RS18050	COG0726	polysaccharide deacetylase
U722_RS18055	COG3842	ATPase activity
U722_RS18060	COG2508	Transcriptional regulator
U722_RS18065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS18075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U722_RS18085	COG4894	glucomannan catabolic process
U722_RS18090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
U722_RS18095	COG0500	methyltransferase
U722_RS18100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_RS18115	COG0693	protein deglycase activity
U722_RS18115	COG0753	catalase activity
U722_RS18120	COG2851	Citrate transporter
U722_RS18125	COG2273	Hydrolase Family 16
U722_RS18135	COG2270	Major facilitator Superfamily
U722_RS18140	COG0513	Belongs to the DEAD box helicase family
U722_RS18205	COG0697	spore germination
U722_RS18210	COG0589	response to stress
U722_RS18260	COG3507	Belongs to the glycosyl hydrolase 43 family
U722_RS18285	COG0010	Belongs to the arginase family
U722_RS18290	COG0833	amino acid
U722_RS18295	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
U722_RS18300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
U722_RS18310	COG2390	Transcriptional regulator
U722_RS18315	COG0561	phosphatase activity
U722_RS18345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
U722_RS18350	COG5294	Protein conserved in bacteria
U722_RS18355	COG0577	efflux transmembrane transporter activity
U722_RS18360	COG1136	(ABC) transporter
U722_RS18365	COG2205	protein histidine kinase activity
U722_RS18370	COG0745	RESPONSE REGULATOR receiver
U722_RS18385	COG1082	Xylose isomerase domain protein TIM barrel
U722_RS18395	COG2814	Major facilitator Superfamily
U722_RS18425	COG1349	DNA-binding transcription factor activity
U722_RS18430	COG0667	Aldo Keto reductase
U722_RS18435	COG2814	Major facilitator Superfamily
U722_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS18455	COG2197	response regulator
U722_RS18460	COG4585	Histidine kinase
U722_RS18465	COG3239	Fatty acid desaturase
U722_RS18475	COG1309	transcriptional regulator
U722_RS18480	COG1012	belongs to the aldehyde dehydrogenase family
U722_RS18485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
U722_RS18495	COG0640	Transcriptional regulator
U722_RS18500	COG2814	Major facilitator Superfamily
U722_RS18505	COG1714	RDD family
U722_RS18515	COG0450	alkyl hydroperoxide reductase
U722_RS18520	COG3634	alkyl hydroperoxide reductase activity
U722_RS18525	COG1113	amino acid transport
U722_RS18535	COG2080	2 iron, 2 sulfur cluster binding
U722_RS18550	COG2068	MobA-Related Protein
U722_RS18555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
U722_RS18590	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
U722_RS18595	COG0667	Aldo Keto reductase
U722_RS18600	COG0456	acetyltransferase
U722_RS18605	COG0457	Tetratricopeptide repeat
U722_RS18610	COG0010	Belongs to the arginase family
U722_RS18615	COG0833	amino acid
U722_RS18620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U722_RS18625	COG3829	transcription factor binding
U722_RS18635	COG0488	(ABC) transporter
U722_RS18650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U722_RS18655	COG3850	Histidine kinase
U722_RS18655	COG5002	protein histidine kinase activity
U722_RS18665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U722_RS18670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
U722_RS18675	COG4853	Protein conserved in bacteria
U722_RS18680	COG4863	YycH protein
U722_RS18685	COG5002	protein histidine kinase activity
U722_RS18690	COG0745	RESPONSE REGULATOR receiver
U722_RS18725	COG0346	lactoylglutathione lyase activity
U722_RS18730	COG0305	Participates in initiation and elongation during chromosome replication
U722_RS18745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
U722_RS18750	COG0297	glycogen (starch) synthase activity
U722_RS18760	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
U722_RS18765	COG0438	transferase activity, transferring glycosyl groups
U722_RS18775	COG0515	serine threonine protein kinase
U722_RS18785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
U722_RS18790	COG4241	membrane
U722_RS18800	COG5577	PFAM Coat F domain
U722_RS18805	COG1733	regulation of RNA biosynthetic process
U722_RS18815	COG0697	spore germination
U722_RS18820	COG1621	beta-fructofuranosidase activity
U722_RS18825	COG1621	beta-fructofuranosidase activity
U722_RS18830	COG1802	Transcriptional regulator
U722_RS18835	COG2318	DinB family
U722_RS18840	COG2211	Major facilitator Superfamily
U722_RS18850	COG0778	Nitroreductase
U722_RS18855	COG1846	Transcriptional regulator
U722_RS18860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
U722_RS18865	COG1846	Transcriptional regulator
U722_RS18880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U722_RS18885	COG0583	DNA-binding transcription factor activity
U722_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
U722_RS18895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U722_RS18900	COG0697	spore germination
U722_RS18910	COG1959	2 iron, 2 sulfur cluster binding
U722_RS18915	COG1396	sequence-specific DNA binding
U722_RS18925	COG1331	Highly conserved protein containing a thioredoxin domain
U722_RS18930	COG1266	CAAX protease self-immunity
U722_RS18935	COG2814	Major facilitator Superfamily
U722_RS18935	COG0477	Major facilitator Superfamily
U722_RS18940	COG0346	lactoylglutathione lyase activity
U722_RS18945	COG1609	Transcriptional regulator
U722_RS18950	COG0708	Exodeoxyribonuclease III
U722_RS18955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U722_RS18960	COG2169	Transcriptional regulator
U722_RS18970	COG0629	single-stranded DNA binding
U722_RS18980	COG0012	GTP binding
U722_RS18985	COG0243	molybdopterin cofactor binding
U722_RS18990	COG4481	Protein conserved in bacteria
U722_RS18995	COG3949	Membrane
U722_RS19010	COG1475	DNA binding
U722_RS19015	COG1192	Involved in chromosome partitioning
U722_RS19040	COG1847	R3H domain protein
U722_RS19045	COG0706	membrane insertase activity