locus-tag	class	description
FZE25_RS00010	COG0592	DNA-directed DNA polymerase activity
FZE25_RS00015	COG2501	S4 domain
FZE25_RS00030	COG0187	DNA topoisomerase II activity
FZE25_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FZE25_RS00070	COG0517	IMP dehydrogenase activity
FZE25_RS00070	COG0516	GMP reductase activity
FZE25_RS00075	COG1686	Belongs to the peptidase S11 family
FZE25_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
FZE25_RS00105	COG1428	Deoxynucleoside kinase
FZE25_RS00110	COG1428	Deoxynucleoside kinase
FZE25_RS00115	COG3858	chitin binding
FZE25_RS00115	COG1388	LysM domain
FZE25_RS00120	COG1335	isochorismatase
FZE25_RS00125	COG0590	tRNA wobble adenosine to inosine editing
FZE25_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FZE25_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FZE25_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FZE25_RS00195	COG3853	Toxic anion resistance protein (TelA)
FZE25_RS00200	COG1982	Orn Lys Arg decarboxylase major
FZE25_RS00210	COG3870	Protein conserved in bacteria
FZE25_RS00215	COG1728	Protein conserved in bacteria
FZE25_RS00220	COG0470	DNA polymerase III
FZE25_RS00225	COG1774	PSP1 C-terminal conserved region
FZE25_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FZE25_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FZE25_RS00250	COG2002	toxin-antitoxin pair type II binding
FZE25_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZE25_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZE25_RS00260	COG0084	hydrolase, TatD family'
FZE25_RS00265	COG3583	domain protein
FZE25_RS00265	COG3584	3D domain protein
FZE25_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FZE25_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FZE25_RS00285	COG4466	Protein conserved in bacteria
FZE25_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FZE25_RS00305	COG0251	oxidation-reduction process
FZE25_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FZE25_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FZE25_RS00345	COG2002	toxin-antitoxin pair type II binding
FZE25_RS00350	COG2244	polysaccharide biosynthetic process
FZE25_RS00355	COG3956	TIGRFAM MazG family protein
FZE25_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FZE25_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FZE25_RS00380	COG1098	S1 RNA binding domain
FZE25_RS00395	COG2208	phosphoserine phosphatase activity
FZE25_RS00400	COG2304	oxidoreductase activity
FZE25_RS00405	COG0515	serine threonine protein kinase
FZE25_RS00410	COG0037	tRNA processing
FZE25_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FZE25_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FZE25_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FZE25_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FZE25_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FZE25_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
FZE25_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FZE25_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FZE25_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FZE25_RS00475	COG1396	sequence-specific DNA binding
FZE25_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FZE25_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FZE25_RS00565	COG4463	regulation of RNA biosynthetic process
FZE25_RS00570	COG3880	PFAM UvrB UvrC protein
FZE25_RS00580	COG0542	response to heat
FZE25_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FZE25_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FZE25_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
FZE25_RS00615	COG1045	serine acetyltransferase
FZE25_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FZE25_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FZE25_RS00635	COG3688	RNA-binding protein containing a PIN domain
FZE25_RS00640	COG1595	DNA-templated transcription, initiation
FZE25_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FZE25_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
FZE25_RS00680	COG2813	Specifically methylates the guanine in position
FZE25_RS00695	COG1358	cellular component organization or biogenesis
FZE25_RS00720	COG0596	Alpha beta hydrolase
FZE25_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FZE25_RS00830	COG0201	protein transport
FZE25_RS00840	COG0024	Methionine aminopeptidase
FZE25_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FZE25_RS00880	COG1122	ATPase activity
FZE25_RS00885	COG1122	ATPase activity
FZE25_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FZE25_RS00910	COG2226	methyltransferase
FZE25_RS00915	COG2318	DinB family
FZE25_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS00930	COG0489	protein tyrosine kinase activity
FZE25_RS00940	COG2194	sulfuric ester hydrolase activity
FZE25_RS00945	COG0726	polysaccharide deacetylase
FZE25_RS01005	COG0738	Major facilitator superfamily
FZE25_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS01020	COG1063	alcohol dehydrogenase
FZE25_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
FZE25_RS01030	COG0385	Bile acid
FZE25_RS01035	COG2819	hydrolase of the alpha beta superfamily
FZE25_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FZE25_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FZE25_RS01055	COG2207	Transcriptional regulator
FZE25_RS01060	COG3876	Protein conserved in bacteria
FZE25_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
FZE25_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FZE25_RS01075	COG1263	PTS System
FZE25_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FZE25_RS01090	COG1683	Conserved Protein
FZE25_RS01120	COG1595	DNA-templated transcription, initiation
FZE25_RS01125	COG5662	AntiSigma factor
FZE25_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FZE25_RS01135	COG4856	YbbR-like protein
FZE25_RS01170	COG1346	cytolysis
FZE25_RS01175	COG1380	Effector of murein hydrolase LrgA
FZE25_RS01180	COG1846	Transcriptional regulator
FZE25_RS01185	COG1113	amino acid transport
FZE25_RS01190	COG1011	Hydrolase
FZE25_RS01195	COG4585	Histidine kinase
FZE25_RS01200	COG2197	response regulator
FZE25_RS01205	COG1131	(ABC) transporter
FZE25_RS01245	COG0531	amino acid
FZE25_RS01250	COG0584	glycerophosphoryl diester phosphodiesterase
FZE25_RS01255	COG2271	Major facilitator Superfamily
FZE25_RS01270	COG2368	4-hydroxyphenylacetate
FZE25_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS01295	COG0371	Dehydrogenase
FZE25_RS01310	COG1183	phosphatidylcholine synthase activity
FZE25_RS01315	COG0586	Pfam SNARE associated Golgi protein
FZE25_RS01320	COG0688	phosphatidylethanolamine metabolic process
FZE25_RS01335	COG1301	dicarboxylic acid transport
FZE25_RS01340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS01345	COG0833	amino acid
FZE25_RS01350	COG2040	homocysteine
FZE25_RS01355	COG1115	amino acid carrier protein
FZE25_RS01360	COG2066	Belongs to the glutaminase family
FZE25_RS01365	COG4191	Histidine kinase
FZE25_RS01370	COG0784	Response regulator, receiver
FZE25_RS01390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FZE25_RS01395	COG0778	Nitroreductase
FZE25_RS01400	COG0346	lactoylglutathione lyase activity
FZE25_RS01405	COG2259	Doxx family
FZE25_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS01425	COG3773	Cell wall hydrolase
FZE25_RS01435	COG3540	Alkaline phosphatase
FZE25_RS01440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FZE25_RS01445	COG0805	protein transport
FZE25_RS01455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FZE25_RS01460	COG0477	Major facilitator Superfamily
FZE25_RS01465	COG1309	transcriptional regulator
FZE25_RS01470	COG0252	asparaginase activity
FZE25_RS01475	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FZE25_RS01480	COG3012	SEC-C Motif Domain Protein
FZE25_RS01480	COG1405	negative regulation of cell septum assembly
FZE25_RS01485	COG0667	Aldo Keto reductase
FZE25_RS01495	COG1595	DNA-templated transcription, initiation
FZE25_RS01500	COG1595	DNA-templated transcription, initiation
FZE25_RS01505	COG1876	peptidase activity
FZE25_RS01510	COG0457	Tetratricopeptide repeat
FZE25_RS01515	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS01520	COG0366	Alpha amylase catalytic
FZE25_RS01525	COG0803	Belongs to the bacterial solute-binding protein 9 family
FZE25_RS01530	COG1121	(ABC) transporter
FZE25_RS01535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FZE25_RS01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS01545	COG2310	stress, protein
FZE25_RS01550	COG2310	stress, protein
FZE25_RS01555	COG2310	stress, protein
FZE25_RS01560	COG0861	Integral membrane protein TerC family
FZE25_RS01570	COG3853	Toxic anion resistance protein (TelA)
FZE25_RS01575	COG0477	Major facilitator Superfamily
FZE25_RS01580	COG0517	IMP dehydrogenase activity
FZE25_RS01580	COG4175	Glycine betaine
FZE25_RS01585	COG4176	ABC-type proline glycine betaine transport system permease component
FZE25_RS01590	COG2113	Glycine betaine
FZE25_RS01595	COG1473	amidohydrolase
FZE25_RS01600	COG1288	antiporter activity
FZE25_RS01610	COG0366	Alpha amylase catalytic
FZE25_RS01620	COG2814	Major facilitator Superfamily
FZE25_RS01625	COG1846	Transcriptional regulator
FZE25_RS01630	COG1280	lysine exporter protein (LysE YggA)
FZE25_RS01635	COG3403	YqcI/YcgG family
FZE25_RS01640	COG1113	amino acid transport
FZE25_RS01645	COG3665	Urea carboxylase-associated protein
FZE25_RS01665	COG1660	Displays ATPase and GTPase activities
FZE25_RS01670	COG1082	Xylose isomerase domain protein TIM barrel
FZE25_RS01675	COG2271	Major facilitator Superfamily
FZE25_RS01680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FZE25_RS01685	COG3458	cephalosporin-C deacetylase activity
FZE25_RS01690	COG3541	Predicted nucleotidyltransferase
FZE25_RS01695	COG0506	proline dehydrogenase activity
FZE25_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS01705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FZE25_RS01710	COG2508	Transcriptional regulator
FZE25_RS01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FZE25_RS01720	COG1587	Uroporphyrinogen-III synthase
FZE25_RS01725	COG2146	nitrite reductase [NAD(P)H] activity
FZE25_RS01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FZE25_RS01735	COG0243	molybdopterin cofactor binding
FZE25_RS01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FZE25_RS01745	COG2223	nitrite transmembrane transporter activity
FZE25_RS01750	COG0523	cobalamin synthesis protein
FZE25_RS01755	COG1063	alcohol dehydrogenase
FZE25_RS01760	COG1714	RDD family
FZE25_RS01770	COG2723	6-phospho-beta-galactosidase activity
FZE25_RS01780	COG3209	COG3209 Rhs family protein
FZE25_RS01785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FZE25_RS01790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FZE25_RS01795	COG1733	regulation of RNA biosynthetic process
FZE25_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FZE25_RS01830	COG0697	spore germination
FZE25_RS01835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS01845	COG2364	Membrane
FZE25_RS01850	COG1126	abc transporter atp-binding protein
FZE25_RS01855	COG0765	amino acid transport
FZE25_RS01860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS01865	COG0583	DNA-binding transcription factor activity
FZE25_RS01870	COG0163	prenyltransferase activity
FZE25_RS01875	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FZE25_RS01890	COG3104	oligopeptide transport
FZE25_RS01895	COG5434	Belongs to the glycosyl hydrolase 28 family
FZE25_RS01905	COG0697	spore germination
FZE25_RS01915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FZE25_RS01920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS01925	COG0456	acetyltransferase
FZE25_RS01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS01935	COG0765	amino acid transport
FZE25_RS01940	COG1126	abc transporter atp-binding protein
FZE25_RS01945	COG1473	amidohydrolase
FZE25_RS01950	COG2079	MmgE PrpD family protein
FZE25_RS01955	COG1136	(ABC) transporter
FZE25_RS01960	COG0577	efflux transmembrane transporter activity
FZE25_RS01965	COG0745	RESPONSE REGULATOR receiver
FZE25_RS01970	COG5002	protein histidine kinase activity
FZE25_RS01970	COG3850	Histidine kinase
FZE25_RS01975	COG0457	Tetratricopeptide repeat
FZE25_RS01990	COG0527	aspartate kinase activity
FZE25_RS01995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS02000	COG4605	iron ion homeostasis
FZE25_RS02005	COG4604	ABC transporter, ATP-binding protein
FZE25_RS02010	COG4607	ABC-type enterochelin transport system periplasmic component
FZE25_RS02015	COG2814	Major facilitator Superfamily
FZE25_RS02020	COG1309	transcriptional regulator
FZE25_RS02025	COG0778	Nitroreductase
FZE25_RS02030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FZE25_RS02035	COG0640	Transcriptional regulator
FZE25_RS02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS02045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS02050	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS02055	COG4975	Glucose uptake
FZE25_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS02065	COG4549	nuclear export factor GLE1
FZE25_RS02070	COG1276	copper resistance
FZE25_RS02070	COG2372	response to copper ion
FZE25_RS02075	COG1349	DNA-binding transcription factor activity
FZE25_RS02085	COG2213	PTS system mannitol-specific
FZE25_RS02090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS02100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FZE25_RS02110	COG0561	phosphatase activity
FZE25_RS02120	COG1914	H( )-stimulated, divalent metal cation uptake system
FZE25_RS02130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FZE25_RS02135	COG1984	allophanate hydrolase subunit 2
FZE25_RS02140	COG1414	Transcriptional regulator
FZE25_RS02145	COG2755	lipolytic protein G-D-S-L family
FZE25_RS02155	COG2329	Antibiotic biosynthesis monooxygenase
FZE25_RS02160	COG0768	penicillin binding
FZE25_RS02165	COG4989	oxidoreductase activity
FZE25_RS02170	COG3711	transcriptional antiterminator
FZE25_RS02175	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS02185	COG1917	Cupin 2, conserved barrel domain protein
FZE25_RS02190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FZE25_RS02195	COG3871	stress protein (general stress protein 26)
FZE25_RS02205	COG2814	Major facilitator Superfamily
FZE25_RS02210	COG1522	sequence-specific DNA binding
FZE25_RS02215	COG0551	DNA topoisomerase type I activity
FZE25_RS02215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FZE25_RS02220	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FZE25_RS02225	COG3706	GGDEF domain
FZE25_RS02230	COG5298	Protein conserved in bacteria
FZE25_RS02235	COG1215	transferase activity, transferring glycosyl groups
FZE25_RS02245	COG0531	amino acid
FZE25_RS02250	COG0494	nUDIX hydrolase
FZE25_RS02255	COG0028	Belongs to the TPP enzyme family
FZE25_RS02280	COG1794	racemase activity, acting on amino acids and derivatives
FZE25_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
FZE25_RS02330	COG4876	unkown
FZE25_RS02340	COG2076	Multidrug Resistance protein
FZE25_RS02345	COG2217	Heavy metal translocating P-type atpase
FZE25_RS02350	COG3729	General stress protein
FZE25_RS02355	COG0662	Cupin 2, conserved barrel domain protein
FZE25_RS02360	COG2329	Antibiotic biosynthesis monooxygenase
FZE25_RS02365	COG3546	catalase activity
FZE25_RS02370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FZE25_RS02375	COG3290	protein histidine kinase activity
FZE25_RS02380	COG4565	transcriptional regulatory protein
FZE25_RS02385	COG1301	dicarboxylic acid transport
FZE25_RS02390	COG0628	permease
FZE25_RS02395	COG1131	(ABC) transporter
FZE25_RS02400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FZE25_RS02410	COG1960	acyl-CoA dehydrogenase activity
FZE25_RS02425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FZE25_RS02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS02440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FZE25_RS02445	COG0513	Belongs to the DEAD box helicase family
FZE25_RS02450	COG3402	PFAM membrane-flanked domain
FZE25_RS02455	COG3428	Bacterial PH domain
FZE25_RS02460	COG0705	Rhomboid family
FZE25_RS02470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FZE25_RS02475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FZE25_RS02480	COG0864	Transcriptional regulator
FZE25_RS02485	COG2337	Toxic component of a toxin-antitoxin (TA) module
FZE25_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS02495	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS02500	COG2172	sigma factor antagonist activity
FZE25_RS02505	COG2208	phosphoserine phosphatase activity
FZE25_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS02520	COG1191	sigma factor activity
FZE25_RS02530	COG2183	response to ionizing radiation
FZE25_RS02595	COG1959	2 iron, 2 sulfur cluster binding
FZE25_RS02600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FZE25_RS02605	COG1090	epimerase
FZE25_RS02610	COG0457	Tetratricopeptide repeat
FZE25_RS02615	COG2249	NAD(P)H dehydrogenase (quinone) activity
FZE25_RS02630	COG0477	Major facilitator Superfamily
FZE25_RS02635	COG1846	Transcriptional regulator
FZE25_RS02645	COG2030	dehydratase
FZE25_RS02660	COG1959	2 iron, 2 sulfur cluster binding
FZE25_RS02665	COG2910	NAD(P)H-binding
FZE25_RS02670	COG1309	transcriptional regulator
FZE25_RS02675	COG0300	oxidoreductase activity
FZE25_RS02685	COG3239	Fatty acid desaturase
FZE25_RS02695	COG1278	Cold shock
FZE25_RS02700	COG1329	Transcriptional regulator
FZE25_RS02720	COG1846	Transcriptional regulator
FZE25_RS02720	COG0456	acetyltransferase
FZE25_RS02725	COG2271	Major facilitator Superfamily
FZE25_RS02730	COG3621	Patatin-like phospholipase
FZE25_RS02740	COG0662	Cupin 2, conserved barrel domain protein
FZE25_RS02755	COG0277	FAD linked oxidase domain protein
FZE25_RS02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FZE25_RS02815	COG0351	phosphomethylpyrimidine kinase
FZE25_RS02830	COG1064	alcohol dehydrogenase
FZE25_RS02835	COG0789	Transcriptional regulator
FZE25_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS02860	COG2814	Major facilitator Superfamily
FZE25_RS02865	COG1309	transcriptional regulator
FZE25_RS02870	COG0697	spore germination
FZE25_RS02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS02880	COG5577	PFAM Coat F domain
FZE25_RS02890	COG1063	alcohol dehydrogenase
FZE25_RS02895	COG5577	PFAM Coat F domain
FZE25_RS02905	COG4585	Histidine kinase
FZE25_RS02910	COG2197	response regulator
FZE25_RS02915	COG2409	Drug exporters of the RND superfamily
FZE25_RS02920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FZE25_RS02925	COG0488	(ABC) transporter
FZE25_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FZE25_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS02945	COG2814	Major facilitator Superfamily
FZE25_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FZE25_RS02960	COG0730	response to heat
FZE25_RS02965	COG0456	acetyltransferase
FZE25_RS02970	COG0789	Transcriptional regulator
FZE25_RS02970	COG4978	Transcriptional regulator
FZE25_RS02975	COG0697	spore germination
FZE25_RS02980	COG1051	belongs to the nudix hydrolase family
FZE25_RS02985	COG2226	methyltransferase
FZE25_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
FZE25_RS02995	COG1802	Transcriptional regulator
FZE25_RS03000	COG1819	glycosyl
FZE25_RS03015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FZE25_RS03020	COG1388	LysM domain
FZE25_RS03025	COG2814	Major facilitator Superfamily
FZE25_RS03030	COG2188	Transcriptional regulator
FZE25_RS03035	COG2186	Transcriptional regulator
FZE25_RS03040	COG2807	transmembrane transport
FZE25_RS03045	COG2076	Multidrug Resistance protein
FZE25_RS03050	COG2076	Multidrug Resistance protein
FZE25_RS03055	COG1309	transcriptional regulator
FZE25_RS03060	COG0531	amino acid
FZE25_RS03070	COG3832	glyoxalase III activity
FZE25_RS03075	COG0604	alcohol dehydrogenase
FZE25_RS03080	COG2814	Major facilitator Superfamily
FZE25_RS03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FZE25_RS03125	COG0802	atpase or kinase
FZE25_RS03130	COG1214	PFAM Peptidase M22, glycoprotease
FZE25_RS03135	COG0456	acetyltransferase
FZE25_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FZE25_RS03145	COG0488	(ABC) transporter
FZE25_RS03160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FZE25_RS03165	COG0805	protein transport
FZE25_RS03175	COG1266	CAAX protease self-immunity
FZE25_RS03195	COG2856	Zn peptidase
FZE25_RS03210	COG1396	sequence-specific DNA binding
FZE25_RS03275	COG3935	DnaD domain protein
FZE25_RS03280	COG1484	DNA-dependent DNA replication
FZE25_RS03355	COG1595	DNA-templated transcription, initiation
FZE25_RS03385	COG5484	DNA packaging
FZE25_RS03505	COG4824	toxin secretion phage lysis holin
FZE25_RS03530	COG0457	Tetratricopeptide repeat
FZE25_RS03535	COG1063	alcohol dehydrogenase
FZE25_RS03540	COG2211	Major facilitator Superfamily
FZE25_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FZE25_RS03555	COG1842	Phage shock protein A
FZE25_RS03560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FZE25_RS03565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FZE25_RS03570	COG4260	virion core protein, lumpy skin disease virus
FZE25_RS03575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FZE25_RS03575	COG2755	lipolytic protein G-D-S-L family
FZE25_RS03585	COG1595	DNA-templated transcription, initiation
FZE25_RS03590	COG1063	alcohol dehydrogenase
FZE25_RS03595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FZE25_RS03600	COG0823	Involved in the tonB-independent uptake of proteins
FZE25_RS03610	COG2132	Multicopper oxidase
FZE25_RS03615	COG1113	amino acid transport
FZE25_RS03620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FZE25_RS03625	COG0714	Associated with various cellular activities
FZE25_RS03630	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FZE25_RS03635	COG1305	Transglutaminase-like
FZE25_RS03660	COG2252	PERMEase
FZE25_RS03665	COG3064	Membrane
FZE25_RS03685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FZE25_RS03690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FZE25_RS03695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FZE25_RS03700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FZE25_RS03705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FZE25_RS03720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FZE25_RS03730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FZE25_RS03735	COG0138	bifunctional purine biosynthesis protein purh
FZE25_RS03740	COG0151	Belongs to the GarS family
FZE25_RS03750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FZE25_RS03755	COG1470	cell adhesion involved in biofilm formation
FZE25_RS03760	COG4496	protein, YerC YecD
FZE25_RS03765	COG0069	glutamate synthase activity
FZE25_RS03775	COG0210	DNA helicase
FZE25_RS03785	COG4851	CamS sex pheromone cAM373 precursor
FZE25_RS03790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FZE25_RS03795	COG1285	pathogenesis
FZE25_RS03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FZE25_RS03820	COG1309	transcriptional regulator
FZE25_RS03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZE25_RS03830	COG1597	lipid kinase activity
FZE25_RS03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FZE25_RS03850	COG0497	DNA recombination
FZE25_RS03880	COG5444	nuclease activity
FZE25_RS03910	COG3546	catalase activity
FZE25_RS03915	COG0454	-acetyltransferase
FZE25_RS03925	COG2323	membrane
FZE25_RS03930	COG2329	Antibiotic biosynthesis monooxygenase
FZE25_RS03935	COG0346	lactoylglutathione lyase activity
FZE25_RS03945	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS03950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FZE25_RS03955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FZE25_RS03960	COG4208	sulfate ABC transporter
FZE25_RS03970	COG5583	Uncharacterized small protein (DUF2292)
FZE25_RS03975	COG0196	riboflavin kinase activity
FZE25_RS03980	COG0670	Belongs to the BI1 family
FZE25_RS03985	COG1846	Transcriptional regulator
FZE25_RS03990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZE25_RS04000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZE25_RS04000	COG2124	cytochrome p450
FZE25_RS04005	COG1368	sulfuric ester hydrolase activity
FZE25_RS04010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FZE25_RS04015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS04020	COG1442	glycosyl transferase family 8
FZE25_RS04025	COG1216	Glycosyl transferase, family 2
FZE25_RS04030	COG1442	glycosyl transferase family 8
FZE25_RS04035	COG2223	nitrite transmembrane transporter activity
FZE25_RS04040	COG0531	amino acid
FZE25_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS04050	COG0840	transmembrane signaling receptor activity
FZE25_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS04060	COG0457	Tetratricopeptide repeat
FZE25_RS04060	COG0463	Glycosyl transferase, family 2
FZE25_RS04065	COG0488	(ABC) transporter
FZE25_RS04070	COG0789	Transcriptional regulator
FZE25_RS04075	COG2814	Major facilitator Superfamily
FZE25_RS04080	COG0488	(ABC) transporter
FZE25_RS04085	COG0513	Belongs to the DEAD box helicase family
FZE25_RS04090	COG0456	acetyltransferase
FZE25_RS04095	COG2130	NADP-dependent
FZE25_RS04110	COG3866	Pectate lyase
FZE25_RS04115	COG0471	metal ion transport
FZE25_RS04140	COG3290	protein histidine kinase activity
FZE25_RS04145	COG4565	transcriptional regulatory protein
FZE25_RS04150	COG3181	Tripartite tricarboxylate transporter family receptor
FZE25_RS04155	COG2851	Citrate transporter
FZE25_RS04160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS04165	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FZE25_RS04175	COG2258	MOSC domain
FZE25_RS04195	COG0024	Methionine aminopeptidase
FZE25_RS04200	COG1263	PTS System
FZE25_RS04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS04210	COG1368	sulfuric ester hydrolase activity
FZE25_RS04220	COG0071	Belongs to the small heat shock protein (HSP20) family
FZE25_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS04235	COG1263	PTS System
FZE25_RS04240	COG0366	Alpha amylase catalytic
FZE25_RS04245	COG2188	Transcriptional regulator
FZE25_RS04250	COG0778	Nitroreductase
FZE25_RS04265	COG0737	Belongs to the 5'-nucleotidase family
FZE25_RS04270	COG0693	protein deglycase activity
FZE25_RS04275	COG1609	Transcriptional regulator
FZE25_RS04290	COG2814	Major facilitator Superfamily
FZE25_RS04300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FZE25_RS04305	COG4980	gas vesicle protein
FZE25_RS04310	COG1295	ribonuclease BN
FZE25_RS04315	COG0477	Major facilitator Superfamily
FZE25_RS04320	COG0387	Pfam Sodium calcium exchanger
FZE25_RS04330	COG0668	transmembrane transport
FZE25_RS04335	COG0535	radical SAM domain protein
FZE25_RS04345	COG0726	polysaccharide deacetylase
FZE25_RS04350	COG2084	Dehydrogenase
FZE25_RS04360	COG0598	Magnesium transport protein CorA
FZE25_RS04365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FZE25_RS04370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FZE25_RS04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FZE25_RS04385	COG4637	Psort location Cytoplasmic, score
FZE25_RS04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FZE25_RS04395	COG0022	dehydrogenase e1 component
FZE25_RS04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZE25_RS04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FZE25_RS04410	COG3284	Transcriptional regulator
FZE25_RS04420	COG1486	melibiose metabolic process
FZE25_RS04425	COG1737	Transcriptional regulator
FZE25_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS04430	COG1263	PTS System
FZE25_RS04435	COG1132	(ABC) transporter
FZE25_RS04440	COG1132	(ABC) transporter
FZE25_RS04445	COG2259	Doxx family
FZE25_RS04450	COG2514	catechol 2,3-dioxygenase activity
FZE25_RS04465	COG1695	Transcriptional regulator
FZE25_RS04470	COG2249	NAD(P)H dehydrogenase (quinone) activity
FZE25_RS04475	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FZE25_RS04480	COG3848	Pyruvate phosphate dikinase
FZE25_RS04480	COG0574	Belongs to the PEP-utilizing enzyme family
FZE25_RS04485	COG2732	(Barnase) inhibitor
FZE25_RS04490	COG2318	DinB family
FZE25_RS04495	COG2814	Major facilitator Superfamily
FZE25_RS04500	COG1846	Transcriptional regulator
FZE25_RS04505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FZE25_RS04505	COG0392	lysyltransferase activity
FZE25_RS04510	COG0384	phenazine biosynthesis protein PhzF
FZE25_RS04515	COG0778	Nitroreductase
FZE25_RS04530	COG1090	epimerase
FZE25_RS04545	COG2814	Major facilitator Superfamily
FZE25_RS04555	COG3591	Belongs to the peptidase S1B family
FZE25_RS04570	COG3103	Sh3 type 3 domain protein
FZE25_RS04575	COG5658	integral membrane protein
FZE25_RS04580	COG0596	Alpha beta hydrolase
FZE25_RS04585	COG0463	Glycosyl transferase, family 2
FZE25_RS04590	COG4485	Bacterial membrane protein, YfhO
FZE25_RS04595	COG1988	membrane-bound metal-dependent
FZE25_RS04600	COG1194	a g-specific adenine glycosylase
FZE25_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS04630	COG1132	(ABC) transporter
FZE25_RS04635	COG4129	membrane
FZE25_RS04645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FZE25_RS04650	COG0735	belongs to the Fur family
FZE25_RS04760	COG1757	Na H antiporter
FZE25_RS04765	COG3340	Belongs to the peptidase S51 family
FZE25_RS04775	COG0277	FAD linked oxidase domain protein
FZE25_RS04785	COG0747	negative chemotaxis
FZE25_RS04790	COG0601	transmembrane transport
FZE25_RS04795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FZE25_RS04800	COG0444	Belongs to the ABC transporter superfamily
FZE25_RS04805	COG4608	Belongs to the ABC transporter superfamily
FZE25_RS04810	COG0753	catalase activity
FZE25_RS04825	COG1116	anion transmembrane transporter activity
FZE25_RS04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FZE25_RS04835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FZE25_RS04855	COG1476	TRANSCRIPTIONal
FZE25_RS04865	COG3382	B3 4 domain protein
FZE25_RS04870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FZE25_RS04880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FZE25_RS04885	COG0789	Transcriptional regulator
FZE25_RS04890	COG1664	Polymer-forming cytoskeletal
FZE25_RS04895	COG1664	Polymer-forming cytoskeletal
FZE25_RS04900	COG2766	serine protein kinase
FZE25_RS04915	COG1846	Transcriptional regulator
FZE25_RS04920	COG1566	PFAM secretion protein HlyD family protein
FZE25_RS04925	COG2814	Major facilitator Superfamily
FZE25_RS04930	COG0655	NAD(P)H dehydrogenase (quinone) activity
FZE25_RS04945	COG1725	Transcriptional regulator
FZE25_RS04950	COG1131	(ABC) transporter
FZE25_RS04955	COG1131	(ABC) transporter
FZE25_RS04960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FZE25_RS04965	COG1278	Cold shock
FZE25_RS04975	COG1464	Belongs to the NlpA lipoprotein family
FZE25_RS04980	COG3706	GGDEF domain
FZE25_RS04985	COG1823	symporter activity
FZE25_RS05005	COG5577	PFAM Coat F domain
FZE25_RS05010	COG4085	toxin activity
FZE25_RS05010	COG0737	Belongs to the 5'-nucleotidase family
FZE25_RS05010	COG1525	nuclease
FZE25_RS05015	COG3764	Sortase (surface protein transpeptidase)
FZE25_RS05020	COG0564	pseudouridine synthase activity
FZE25_RS05030	COG0517	IMP dehydrogenase activity
FZE25_RS05035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FZE25_RS05040	COG3153	acetyltransferase
FZE25_RS05040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FZE25_RS05045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FZE25_RS05050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FZE25_RS05055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FZE25_RS05065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FZE25_RS05070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FZE25_RS05075	COG2203	Gaf domain
FZE25_RS05075	COG4585	Histidine kinase
FZE25_RS05080	COG2197	response regulator
FZE25_RS05085	COG0431	NADPH-dependent FMN reductase
FZE25_RS05100	COG1388	LysM domain
FZE25_RS05100	COG0791	NLP P60 protein
FZE25_RS05105	COG1959	2 iron, 2 sulfur cluster binding
FZE25_RS05110	COG0668	transmembrane transport
FZE25_RS05115	COG2719	SpoVR family
FZE25_RS05120	COG1785	Belongs to the alkaline phosphatase family
FZE25_RS05125	COG0791	NLP P60 protein
FZE25_RS05125	COG1388	LysM domain
FZE25_RS05130	COG0583	DNA-binding transcription factor activity
FZE25_RS05135	COG0372	Belongs to the citrate synthase family
FZE25_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS05145	COG0531	amino acid
FZE25_RS05150	COG0733	neurotransmitter:sodium symporter activity
FZE25_RS05165	COG1595	DNA-templated transcription, initiation
FZE25_RS05170	COG0204	Acyl-transferase
FZE25_RS05175	COG1253	flavin adenine dinucleotide binding
FZE25_RS05180	COG0789	Transcriptional regulator
FZE25_RS05185	COG0436	Aminotransferase
FZE25_RS05190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FZE25_RS05195	COG1253	flavin adenine dinucleotide binding
FZE25_RS05200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FZE25_RS05205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FZE25_RS05210	COG0584	glycerophosphoryl diester phosphodiesterase
FZE25_RS05220	COG0668	transmembrane transport
FZE25_RS05230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FZE25_RS05235	COG0726	polysaccharide deacetylase
FZE25_RS05240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS05245	COG3226	Transcriptional regulator
FZE25_RS05255	COG0589	response to stress
FZE25_RS05260	COG1132	(ABC) transporter
FZE25_RS05265	COG1132	(ABC) transporter
FZE25_RS05270	COG0702	epimerase
FZE25_RS05290	COG0189	ligase activity
FZE25_RS05295	COG0189	ligase activity
FZE25_RS05310	COG4335	DNA alkylation repair
FZE25_RS05315	COG0561	phosphatase activity
FZE25_RS05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FZE25_RS05330	COG0475	glutathione-regulated potassium exporter activity
FZE25_RS05335	COG0490	domain, Protein
FZE25_RS05345	COG1024	Enoyl-CoA hydratase
FZE25_RS05355	COG4152	abc transporter atp-binding protein
FZE25_RS05360	COG1668	transmembrane transport
FZE25_RS05365	COG0420	3'-5' exonuclease activity
FZE25_RS05370	COG4717	serine-type aminopeptidase activity
FZE25_RS05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FZE25_RS05430	COG4980	gas vesicle protein
FZE25_RS05445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FZE25_RS05450	COG0537	adenosine 5'-monophosphoramidase activity
FZE25_RS05455	COG1131	(ABC) transporter
FZE25_RS05460	COG4473	ABC transporter
FZE25_RS05470	COG1473	amidohydrolase
FZE25_RS05475	COG3069	C4-dicarboxylate transmembrane transporter activity
FZE25_RS05480	COG2329	Antibiotic biosynthesis monooxygenase
FZE25_RS05485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZE25_RS05495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FZE25_RS05500	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FZE25_RS05505	COG1309	transcriptional regulator
FZE25_RS05510	COG1511	domain protein
FZE25_RS05515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZE25_RS05525	COG1363	Peptidase, m42
FZE25_RS05530	COG1301	dicarboxylic acid transport
FZE25_RS05540	COG1234	tRNA 3'-trailer cleavage
FZE25_RS05545	COG0095	Lipoate-protein ligase
FZE25_RS05550	COG0702	epimerase
FZE25_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS05565	COG0501	Belongs to the peptidase M48B family
FZE25_RS05570	COG1404	Belongs to the peptidase S8 family
FZE25_RS05580	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FZE25_RS05585	COG0406	alpha-ribazole phosphatase activity
FZE25_RS05590	COG0183	Belongs to the thiolase family
FZE25_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS05600	COG1268	BioY protein
FZE25_RS05605	COG0840	transmembrane signaling receptor activity
FZE25_RS05610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZE25_RS05610	COG0723	plastoquinol--plastocyanin reductase activity
FZE25_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS05625	COG4903	ComK protein
FZE25_RS05635	COG5646	InterPro IPR014922
FZE25_RS05660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FZE25_RS05675	COG0398	Pfam SNARE associated Golgi protein
FZE25_RS05680	COG0681	Belongs to the peptidase S26 family
FZE25_RS05685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZE25_RS05690	COG1846	Transcriptional regulator
FZE25_RS05695	COG3180	Ammonia monooxygenase
FZE25_RS05700	COG2814	Major facilitator Superfamily
FZE25_RS05710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FZE25_RS05715	COG2323	membrane
FZE25_RS05730	COG0420	3'-5' exonuclease activity
FZE25_RS05735	COG0419	ATPase involved in DNA repair
FZE25_RS05740	COG1403	HNH endonuclease
FZE25_RS05780	COG0179	Fumarylacetoacetate (FAA) hydrolase
FZE25_RS05800	COG0367	asparagine synthase
FZE25_RS05805	COG1562	ergosterol biosynthetic process
FZE25_RS05810	COG0534	Mate efflux family protein
FZE25_RS05815	COG1917	Cupin 2, conserved barrel domain protein
FZE25_RS05815	COG2207	Transcriptional regulator
FZE25_RS05820	COG2318	DinB family
FZE25_RS05825	COG1279	arginine transmembrane transporter activity
FZE25_RS05830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS05835	COG1357	PFAM Pentapeptide repeats (8 copies)
FZE25_RS05840	COG2153	protein acetylation
FZE25_RS05845	COG0646	methionine synthase
FZE25_RS05845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FZE25_RS05855	COG2996	Protein conserved in bacteria
FZE25_RS05860	COG1744	ABC transporter substrate-binding protein PnrA-like
FZE25_RS05865	COG0840	transmembrane signaling receptor activity
FZE25_RS05870	COG2124	cytochrome p450
FZE25_RS05880	COG1307	EDD domain protein, DegV family
FZE25_RS05885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS05900	COG0561	phosphatase activity
FZE25_RS05905	COG1073	alpha beta
FZE25_RS05910	COG2151	metal-sulfur cluster biosynthetic enzyme
FZE25_RS05920	COG0277	FAD linked oxidase domain protein
FZE25_RS05925	COG2271	Major facilitator Superfamily
FZE25_RS05935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FZE25_RS05945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FZE25_RS05950	COG0505	Belongs to the CarA family
FZE25_RS05955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FZE25_RS05960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FZE25_RS05980	COG2267	carboxylic ester hydrolase activity
FZE25_RS05990	COG1744	ABC transporter substrate-binding protein PnrA-like
FZE25_RS06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZE25_RS06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FZE25_RS06015	COG5504	Zn-dependent protease
FZE25_RS06020	COG0444	Belongs to the ABC transporter superfamily
FZE25_RS06025	COG4608	Belongs to the ABC transporter superfamily
FZE25_RS06035	COG0601	transmembrane transport
FZE25_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FZE25_RS06050	COG0180	Tryptophanyl-tRNA synthetase
FZE25_RS06055	COG4166	transmembrane transport
FZE25_RS06060	COG0601	transmembrane transport
FZE25_RS06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FZE25_RS06070	COG0444	Belongs to the ABC transporter superfamily
FZE25_RS06075	COG4608	Belongs to the ABC transporter superfamily
FZE25_RS06085	COG0456	acetyltransferase
FZE25_RS06090	COG1393	Belongs to the ArsC family
FZE25_RS06095	COG0861	Integral membrane protein TerC family
FZE25_RS06100	COG4862	establishment of competence for transformation
FZE25_RS06105	COG4469	Competence protein
FZE25_RS06110	COG1164	Oligoendopeptidase f
FZE25_RS06115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FZE25_RS06120	COG2346	COG2346, Truncated hemoglobins
FZE25_RS06125	COG0741	lytic transglycosylase activity
FZE25_RS06130	COG4116	CYTH
FZE25_RS06140	COG2357	RelA SpoT domain protein
FZE25_RS06145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FZE25_RS06150	COG0564	pseudouridine synthase activity
FZE25_RS06165	COG0569	domain protein
FZE25_RS06165	COG0475	glutathione-regulated potassium exporter activity
FZE25_RS06170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FZE25_RS06175	COG0352	thiamine-phosphate diphosphorylase activity
FZE25_RS06180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZE25_RS06185	COG2104	thiamine diphosphate biosynthetic process
FZE25_RS06195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FZE25_RS06200	COG0351	phosphomethylpyrimidine kinase
FZE25_RS06205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FZE25_RS06260	COG0210	DNA helicase
FZE25_RS06290	COG2153	protein acetylation
FZE25_RS06300	COG2382	esterase
FZE25_RS06305	COG0626	cystathionine gamma-synthase activity
FZE25_RS06310	COG0626	cystathionine gamma-synthase activity
FZE25_RS06375	COG2367	Beta-lactamase
FZE25_RS06380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FZE25_RS06390	COG1846	Transcriptional regulator
FZE25_RS06400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FZE25_RS06405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FZE25_RS06410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FZE25_RS06415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS06415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS06420	COG1447	Phosphotransferase system cellobiose-specific component IIA
FZE25_RS06455	COG1285	pathogenesis
FZE25_RS06470	COG2205	protein histidine kinase activity
FZE25_RS06480	COG3383	formate dehydrogenase (NAD+) activity
FZE25_RS06485	COG2427	Protein of unknown function (DUF1641)
FZE25_RS06490	COG2124	cytochrome p450
FZE25_RS06495	COG1819	glycosyl
FZE25_RS06505	COG1587	Uroporphyrinogen-III synthase
FZE25_RS06510	COG0390	transport system, permease component
FZE25_RS06515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FZE25_RS06520	COG0697	spore germination
FZE25_RS06525	COG4297	protein containing double-stranded beta helix domain
FZE25_RS06535	COG1252	NADH dehydrogenase
FZE25_RS06545	COG2211	Major facilitator Superfamily
FZE25_RS06550	COG1609	Transcriptional regulator
FZE25_RS06555	COG0246	Mannitol dehydrogenase
FZE25_RS06560	COG2721	sulfolactate sulfo-lyase activity
FZE25_RS06565	COG0730	response to heat
FZE25_RS06570	COG2318	DinB family
FZE25_RS06575	COG0457	Tetratricopeptide repeat
FZE25_RS06585	COG1388	LysM domain
FZE25_RS06585	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS06585	COG5632	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS06595	COG4195	phage-related replication protein
FZE25_RS06600	COG2856	Zn peptidase
FZE25_RS06605	COG1396	sequence-specific DNA binding
FZE25_RS06615	COG1522	sequence-specific DNA binding
FZE25_RS06620	COG1484	DNA-dependent DNA replication
FZE25_RS06635	COG1595	DNA-templated transcription, initiation
FZE25_RS06640	COG3728	DNA packaging
FZE25_RS06640	COG5484	DNA packaging
FZE25_RS06645	COG1783	phage Terminase large subunit
FZE25_RS06650	COG5518	Phage portal protein
FZE25_RS06655	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FZE25_RS06660	COG4653	Phage capsid family
FZE25_RS06710	COG5412	phage tail tape measure protein
FZE25_RS06710	COG5412	phage tail tape measure protein
FZE25_RS06710	COG3953	SLT domain
FZE25_RS06710	COG3953	SLT domain
FZE25_RS06710	COG3953	SLT domain
FZE25_RS06710	COG5412	phage tail tape measure protein
FZE25_RS06715	COG1652	LysM domain
FZE25_RS06720	COG4193	domain, Protein
FZE25_RS06730	COG3628	GPW Gp25 family protein
FZE25_RS06735	COG3299	homolog of phage Mu protein gp47
FZE25_RS06740	COG3778	Protein conserved in bacteria
FZE25_RS06780	COG5632	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS06780	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS06795	COG0306	phosphate transporter
FZE25_RS06800	COG1392	Phosphate transport regulator
FZE25_RS06805	COG0531	amino acid
FZE25_RS06810	COG0346	lactoylglutathione lyase activity
FZE25_RS06815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FZE25_RS06820	COG0463	Glycosyl transferase, family 2
FZE25_RS06825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZE25_RS06830	COG0477	Major facilitator Superfamily
FZE25_RS06835	COG2362	D-Aminopeptidase
FZE25_RS06840	COG0601	transmembrane transport
FZE25_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FZE25_RS06850	COG0444	Belongs to the ABC transporter superfamily
FZE25_RS06855	COG4166	transmembrane transport
FZE25_RS06860	COG1619	proteins homologs of microcin C7 resistance protein MccF
FZE25_RS06865	COG4948	Mandelate Racemase Muconate Lactonizing
FZE25_RS06870	COG0791	NLP P60 protein
FZE25_RS06875	COG4608	Belongs to the ABC transporter superfamily
FZE25_RS06880	COG2706	6-phosphogluconolactonase activity
FZE25_RS06885	COG1834	amidinotransferase
FZE25_RS06890	COG1607	acyl-coa hydrolase
FZE25_RS06895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FZE25_RS06900	COG2076	Multidrug Resistance protein
FZE25_RS06905	COG2076	Multidrug Resistance protein
FZE25_RS06910	COG0788	formyltetrahydrofolate deformylase activity
FZE25_RS06915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FZE25_RS06925	COG1764	response to oxidative stress
FZE25_RS06930	COG1846	Transcriptional regulator
FZE25_RS06935	COG1764	response to oxidative stress
FZE25_RS06950	COG0463	Glycosyl transferase, family 2
FZE25_RS06950	COG0457	Tetratricopeptide repeat
FZE25_RS06960	COG2814	Major facilitator Superfamily
FZE25_RS06965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FZE25_RS06975	COG1404	Belongs to the peptidase S8 family
FZE25_RS06980	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS06985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FZE25_RS06990	COG1122	ATPase activity
FZE25_RS06995	COG4721	ABC-type cobalt transport system, permease component
FZE25_RS07000	COG3858	chitin binding
FZE25_RS07000	COG1388	LysM domain
FZE25_RS07020	COG2239	Acts as a magnesium transporter
FZE25_RS07025	COG0789	Transcriptional regulator
FZE25_RS07040	COG1846	Transcriptional regulator
FZE25_RS07045	COG0726	polysaccharide deacetylase
FZE25_RS07050	COG1793	dna ligase
FZE25_RS07050	COG3285	dna ligase
FZE25_RS07055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FZE25_RS07060	COG0586	Pfam SNARE associated Golgi protein
FZE25_RS07065	COG0861	Integral membrane protein TerC family
FZE25_RS07070	COG1191	sigma factor activity
FZE25_RS07095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FZE25_RS07100	COG2323	membrane
FZE25_RS07110	COG3594	Acyltransferase
FZE25_RS07115	COG5002	protein histidine kinase activity
FZE25_RS07120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FZE25_RS07135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FZE25_RS07140	COG0436	Aminotransferase
FZE25_RS07170	COG3852	Histidine kinase
FZE25_RS07175	COG1846	Transcriptional regulator
FZE25_RS07180	COG1360	Flagellar Motor Protein
FZE25_RS07185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FZE25_RS07190	COG0542	response to heat
FZE25_RS07200	COG3949	Membrane
FZE25_RS07215	COG0720	synthase
FZE25_RS07220	COG0602	queuosine metabolic process
FZE25_RS07230	COG1733	regulation of RNA biosynthetic process
FZE25_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS07245	COG1388	LysM domain
FZE25_RS07245	COG4641	Protein conserved in bacteria
FZE25_RS07250	COG1388	LysM domain
FZE25_RS07255	COG3858	chitin binding
FZE25_RS07270	COG4873	Protein conserved in bacteria
FZE25_RS07280	COG3773	Cell wall hydrolase
FZE25_RS07285	COG2244	polysaccharide biosynthetic process
FZE25_RS07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS07295	COG2217	Heavy metal translocating P-type atpase
FZE25_RS07300	COG0006	proline dipeptidase activity
FZE25_RS07305	COG1609	Transcriptional regulator
FZE25_RS07310	COG3711	transcriptional antiterminator
FZE25_RS07315	COG1263	PTS System
FZE25_RS07315	COG2190	(PTS) system
FZE25_RS07315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS07320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS07325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FZE25_RS07335	COG1533	DNA photolyase activity
FZE25_RS07340	COG0840	transmembrane signaling receptor activity
FZE25_RS07345	COG2084	Dehydrogenase
FZE25_RS07350	COG2340	Cysteine-rich secretory protein family
FZE25_RS07355	COG0768	penicillin binding
FZE25_RS07360	COG4191	Histidine kinase
FZE25_RS07365	COG0436	Aminotransferase
FZE25_RS07375	COG0784	Response regulator, receiver
FZE25_RS07375	COG0835	chemotaxis
FZE25_RS07385	COG2814	Major facilitator Superfamily
FZE25_RS07390	COG1376	ErfK ybiS ycfS ynhG family protein
FZE25_RS07395	COG1408	metallophosphoesterase
FZE25_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS07410	COG2200	EAL domain
FZE25_RS07415	COG4703	Protein of unknown function (DUF1797)
FZE25_RS07420	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FZE25_RS07430	COG0517	IMP dehydrogenase activity
FZE25_RS07435	COG0583	DNA-binding transcription factor activity
FZE25_RS07440	COG0716	FMN binding
FZE25_RS07450	COG0716	FMN binding
FZE25_RS07470	COG0668	transmembrane transport
FZE25_RS07475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS07495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FZE25_RS07500	COG0303	'Molybdopterin
FZE25_RS07505	COG1763	Mo-molybdopterin cofactor biosynthetic process
FZE25_RS07510	COG0314	molybdopterin synthase activity
FZE25_RS07515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FZE25_RS07525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZE25_RS07530	COG1136	(ABC) transporter
FZE25_RS07535	COG0577	efflux transmembrane transporter activity
FZE25_RS07540	COG1349	DNA-binding transcription factor activity
FZE25_RS07545	COG1105	Belongs to the carbohydrate kinase PfkB family
FZE25_RS07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZE25_RS07550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZE25_RS07555	COG0681	Belongs to the peptidase S26 family
FZE25_RS07565	COG0488	(ABC) transporter
FZE25_RS07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FZE25_RS07575	COG2309	aminopeptidase activity
FZE25_RS07585	COG1077	Cell shape determining protein MreB Mrl
FZE25_RS07595	COG2002	toxin-antitoxin pair type II binding
FZE25_RS07600	COG3852	Histidine kinase
FZE25_RS07605	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FZE25_RS07605	COG2105	PFAM AIG2 family protein
FZE25_RS07610	COG0569	domain protein
FZE25_RS07620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FZE25_RS07630	COG0561	phosphatase activity
FZE25_RS07635	COG0242	peptide deformylase activity
FZE25_RS07645	COG0497	DNA recombination
FZE25_RS07660	COG4221	oxidoreductase activity
FZE25_RS07660	COG3321	synthase
FZE25_RS07660	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS07660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS07665	COG4221	oxidoreductase activity
FZE25_RS07665	COG3321	synthase
FZE25_RS07665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS07665	COG0300	oxidoreductase activity
FZE25_RS07670	COG4221	oxidoreductase activity
FZE25_RS07670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS07670	COG3321	synthase
FZE25_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS07675	COG4221	oxidoreductase activity
FZE25_RS07675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS07675	COG0300	oxidoreductase activity
FZE25_RS07675	COG3321	synthase
FZE25_RS07680	COG3321	synthase
FZE25_RS07680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS07680	COG0300	oxidoreductase activity
FZE25_RS07680	COG4221	oxidoreductase activity
FZE25_RS07685	COG4221	oxidoreductase activity
FZE25_RS07685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS07685	COG3321	synthase
FZE25_RS07685	COG0300	oxidoreductase activity
FZE25_RS07690	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS07690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS07690	COG3321	synthase
FZE25_RS07690	COG4221	oxidoreductase activity
FZE25_RS07695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FZE25_RS07700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FZE25_RS07705	COG0022	dehydrogenase e1 component
FZE25_RS07710	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZE25_RS07715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FZE25_RS07720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS07735	COG1982	Orn Lys Arg decarboxylase major
FZE25_RS07760	COG0483	inositol monophosphate 1-phosphatase activity
FZE25_RS07770	COG3227	Zinc metalloprotease (Elastase)
FZE25_RS07795	COG1217	gtp-binding protein TYPA
FZE25_RS07805	COG4896	Protein conserved in bacteria
FZE25_RS07815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FZE25_RS07820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FZE25_RS07825	COG2066	Belongs to the glutaminase family
FZE25_RS07835	COG0772	Belongs to the SEDS family
FZE25_RS07840	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FZE25_RS07855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FZE25_RS07855	COG2010	Cytochrome c
FZE25_RS07860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FZE25_RS07865	COG1845	cytochrome c oxidase, subunit III
FZE25_RS07870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FZE25_RS07875	COG3336	cytochrome c oxidase
FZE25_RS07890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FZE25_RS07895	COG2340	Cysteine-rich secretory protein family
FZE25_RS07910	COG3679	Belongs to the UPF0342 family
FZE25_RS07925	COG0742	ribosomal rna small subunit methyltransferase
FZE25_RS07935	COG3314	Sporulation integral membrane protein YlbJ
FZE25_RS07940	COG1752	Esterase of the alpha-beta hydrolase superfamily
FZE25_RS07945	COG3480	Lon protease (S16) C-terminal proteolytic domain
FZE25_RS07955	COG1399	metal-binding, possibly nucleic acid-binding protein
FZE25_RS07975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FZE25_RS07995	COG4839	cell division protein FtsL
FZE25_RS08000	COG0768	penicillin binding
FZE25_RS08005	COG0768	penicillin binding
FZE25_RS08025	COG0772	Belongs to the SEDS family
FZE25_RS08040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FZE25_RS08045	COG0849	cell division
FZE25_RS08050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FZE25_RS08055	COG4412	M6 family metalloprotease domain protein
FZE25_RS08055	COG1404	Belongs to the peptidase S8 family
FZE25_RS08065	COG1191	sigma factor activity
FZE25_RS08070	COG1191	sigma factor activity
FZE25_RS08075	COG1119	ATPase activity
FZE25_RS08080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZE25_RS08085	COG1873	PFAM PRC-barrel domain
FZE25_RS08090	COG1496	oxidoreductase activity
FZE25_RS08095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FZE25_RS08105	COG0762	integral membrane protein
FZE25_RS08110	COG2302	S4 RNA-binding domain
FZE25_RS08115	COG3599	regulation of cell shape
FZE25_RS08120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FZE25_RS08125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FZE25_RS08135	COG0564	pseudouridine synthase activity
FZE25_RS08145	COG2233	PERMEase
FZE25_RS08155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FZE25_RS08160	COG0505	Belongs to the CarA family
FZE25_RS08165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FZE25_RS08180	COG0284	orotidine-5'-phosphate decarboxylase activity
FZE25_RS08185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FZE25_RS08195	COG0306	phosphate transporter
FZE25_RS08210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FZE25_RS08215	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FZE25_RS08220	COG1648	precorrin-2 dehydrogenase activity
FZE25_RS08235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FZE25_RS08240	COG1561	YicC-like family, N-terminal region
FZE25_RS08250	COG0194	GDP metabolic process
FZE25_RS08260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FZE25_RS08265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FZE25_RS08270	COG0242	peptide deformylase activity
FZE25_RS08280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FZE25_RS08280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FZE25_RS08290	COG0631	protein serine/threonine phosphatase activity
FZE25_RS08295	COG2815	serine threonine protein kinase
FZE25_RS08295	COG0515	serine threonine protein kinase
FZE25_RS08305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FZE25_RS08310	COG1564	THIamine pyrophosphokinase
FZE25_RS08325	COG1302	Protein conserved in bacteria
FZE25_RS08330	COG1461	Dihydroxyacetone kinase
FZE25_RS08335	COG1760	l-serine dehydratase
FZE25_RS08340	COG1760	l-serine dehydratase
FZE25_RS08345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FZE25_RS08360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FZE25_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS08380	COG1196	nuclear chromosome segregation
FZE25_RS08385	COG0552	protein localization to endoplasmic reticulum
FZE25_RS08400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FZE25_RS08410	COG1837	Belongs to the UPF0109 family
FZE25_RS08435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FZE25_RS08450	COG2257	FlhB HrpN YscU SpaS Family
FZE25_RS08460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FZE25_RS08465	COG0758	DNA mediated transformation
FZE25_RS08470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FZE25_RS08480	COG4974	Belongs to the 'phage' integrase family
FZE25_RS08500	COG1815	bacterial-type flagellum-dependent cell motility
FZE25_RS08505	COG1558	bacterial-type flagellum-dependent cell motility
FZE25_RS08510	COG1677	Flagellar hook-basal body complex protein FliE
FZE25_RS08515	COG1766	The M ring may be actively involved in energy transduction
FZE25_RS08520	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FZE25_RS08525	COG1317	bacterial-type flagellum organization
FZE25_RS08530	COG1157	protein secretion by the type III secretion system
FZE25_RS08535	COG2882	bacterial-type flagellum organization
FZE25_RS08540	COG3334	PFAM MgtE intracellular
FZE25_RS08545	COG3144	bacterial-type flagellum assembly
FZE25_RS08550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FZE25_RS08555	COG4786	Flagellar basal body rod
FZE25_RS08560	COG1582	Flagellar protein (FlbD)
FZE25_RS08565	COG1580	Controls the rotational direction of flagella during chemotaxis
FZE25_RS08570	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FZE25_RS08575	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FZE25_RS08575	COG1776	CheC inhibitor of MCP methylation
FZE25_RS08580	COG2201	protein-glutamate methylesterase activity
FZE25_RS08585	COG3190	flagellar
FZE25_RS08590	COG1338	Plays a role in the flagellum-specific transport system
FZE25_RS08595	COG1987	bacterial-type flagellum assembly
FZE25_RS08600	COG1684	flagellar biosynthetic protein fliR
FZE25_RS08605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FZE25_RS08610	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FZE25_RS08615	COG1419	protein localization to endoplasmic reticulum
FZE25_RS08620	COG0455	bacterial-type flagellum organization
FZE25_RS08625	COG2201	protein-glutamate methylesterase activity
FZE25_RS08630	COG2198	Histidine kinase
FZE25_RS08630	COG0643	Histidine kinase
FZE25_RS08635	COG0835	chemotaxis
FZE25_RS08640	COG1776	CheC inhibitor of MCP methylation
FZE25_RS08650	COG1191	sigma factor activity
FZE25_RS08680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FZE25_RS08685	COG4589	Belongs to the CDS family
FZE25_RS08695	COG0750	zinc metalloprotease
FZE25_RS08705	COG2176	DNA-directed DNA polymerase activity
FZE25_RS08715	COG0195	Participates in both transcription termination and antitermination
FZE25_RS08720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FZE25_RS08725	COG1358	cellular component organization or biogenesis
FZE25_RS08735	COG1550	Protein conserved in bacteria
FZE25_RS08750	COG0196	riboflavin kinase activity
FZE25_RS08765	COG0726	polysaccharide deacetylase
FZE25_RS08770	COG0612	Peptidase, M16
FZE25_RS08775	COG1873	PFAM PRC-barrel domain
FZE25_RS08780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FZE25_RS08785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FZE25_RS08790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FZE25_RS08795	COG0527	aspartate kinase activity
FZE25_RS08805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FZE25_RS08810	COG0740	serine-type endopeptidase activity
FZE25_RS08820	COG1674	ftsk spoiiie
FZE25_RS08820	COG4980	gas vesicle protein
FZE25_RS08825	COG2188	Transcriptional regulator
FZE25_RS08830	COG2814	Major facilitator Superfamily
FZE25_RS08835	COG1846	Transcriptional regulator
FZE25_RS08840	COG1033	growth of symbiont in host cell
FZE25_RS08840	COG2409	Drug exporters of the RND superfamily
FZE25_RS08845	COG0612	Peptidase, M16
FZE25_RS08850	COG0612	Peptidase, M16
FZE25_RS08855	COG0300	oxidoreductase activity
FZE25_RS08870	COG1426	Protein conserved in bacteria
FZE25_RS08875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FZE25_RS08890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FZE25_RS08900	COG1692	metallophosphoesterase
FZE25_RS08905	COG2359	stage V sporulation protein S
FZE25_RS08925	COG4550	Control of competence regulator ComK, YlbF/YmcA
FZE25_RS08945	COG0582	viral genome integration into host DNA
FZE25_RS08995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS09000	COG3425	synthase
FZE25_RS09005	COG1024	Enoyl-CoA hydratase
FZE25_RS09010	COG1024	Enoyl-CoA hydratase
FZE25_RS09015	COG3321	synthase
FZE25_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09015	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS09015	COG0300	oxidoreductase activity
FZE25_RS09020	COG3321	synthase
FZE25_RS09020	COG4221	oxidoreductase activity
FZE25_RS09020	COG0300	oxidoreductase activity
FZE25_RS09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS09025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09025	COG3321	synthase
FZE25_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS09025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS09025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS09025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09025	COG3321	synthase
FZE25_RS09030	COG4221	oxidoreductase activity
FZE25_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09030	COG3321	synthase
FZE25_RS09035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FZE25_RS09035	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FZE25_RS09035	COG3321	synthase
FZE25_RS09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS09040	COG2124	cytochrome p450
FZE25_RS09045	COG3209	COG3209 Rhs family protein
FZE25_RS09050	COG3619	membrane
FZE25_RS09060	COG1404	Belongs to the peptidase S8 family
FZE25_RS09070	COG4195	phage-related replication protein
FZE25_RS09075	COG1764	response to oxidative stress
FZE25_RS09085	COG2076	Multidrug Resistance protein
FZE25_RS09125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FZE25_RS09130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FZE25_RS09135	COG4112	unkown
FZE25_RS09140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS09150	COG0464	growth
FZE25_RS09155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FZE25_RS09160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FZE25_RS09165	COG0789	Transcriptional regulator
FZE25_RS09170	COG0174	glutamine synthetase
FZE25_RS09180	COG2211	Major facilitator Superfamily
FZE25_RS09185	COG3507	Belongs to the glycosyl hydrolase 43 family
FZE25_RS09200	COG1070	Carbohydrate kinase
FZE25_RS09205	COG3848	Pyruvate phosphate dikinase
FZE25_RS09205	COG0574	Belongs to the PEP-utilizing enzyme family
FZE25_RS09230	COG1064	alcohol dehydrogenase
FZE25_RS09240	COG0456	acetyltransferase
FZE25_RS09275	COG3397	chitin binding
FZE25_RS09295	COG5434	Belongs to the glycosyl hydrolase 28 family
FZE25_RS09300	COG0756	dUTP diphosphatase activity
FZE25_RS09310	COG4195	phage-related replication protein
FZE25_RS09340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FZE25_RS09350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FZE25_RS09370	COG0785	Cytochrome C biogenesis protein
FZE25_RS09375	COG2201	protein-glutamate methylesterase activity
FZE25_RS09380	COG4846	Membrane protein involved in cytochrome C biogenesis
FZE25_RS09390	COG0071	Belongs to the small heat shock protein (HSP20) family
FZE25_RS09405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FZE25_RS09410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS09430	COG0824	Thioesterase
FZE25_RS09440	COG4841	protein insertion into membrane
FZE25_RS09450	COG1832	CoA-binding protein
FZE25_RS09455	COG0187	DNA topoisomerase II activity
FZE25_RS09460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FZE25_RS09470	COG1115	amino acid carrier protein
FZE25_RS09480	COG1063	alcohol dehydrogenase
FZE25_RS09485	COG0800	Aldolase
FZE25_RS09490	COG1312	Catalyzes the dehydration of D-mannonate
FZE25_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09500	COG1609	Transcriptional regulator
FZE25_RS09505	COG2271	Major facilitator Superfamily
FZE25_RS09550	COG2205	protein histidine kinase activity
FZE25_RS09555	COG0745	RESPONSE REGULATOR receiver
FZE25_RS09565	COG3507	Belongs to the glycosyl hydrolase 43 family
FZE25_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS09595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FZE25_RS09600	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FZE25_RS09605	COG2610	gluconate transmembrane transporter activity
FZE25_RS09610	COG2124	cytochrome p450
FZE25_RS09630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FZE25_RS09640	COG2246	polysaccharide biosynthetic process
FZE25_RS09645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FZE25_RS09650	COG0586	Pfam SNARE associated Golgi protein
FZE25_RS09655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FZE25_RS09660	COG1024	Enoyl-CoA hydratase
FZE25_RS09665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FZE25_RS09670	COG0511	ligase activity, forming carbon-carbon bonds
FZE25_RS09675	COG0439	Biotin carboxylase
FZE25_RS09680	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS09685	COG1960	acyl-CoA dehydrogenase activity
FZE25_RS09690	COG1649	PFAM Uncharacterised BCR, COG1649
FZE25_RS09700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FZE25_RS09705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS09730	COG2027	D-alanyl-D-alanine carboxypeptidase
FZE25_RS09735	COG2017	converts alpha-aldose to the beta-anomer
FZE25_RS09740	COG0534	Mate efflux family protein
FZE25_RS09755	COG0582	viral genome integration into host DNA
FZE25_RS09760	COG0166	Belongs to the GPI family
FZE25_RS09765	COG0405	Gamma-glutamyltransferase
FZE25_RS09770	COG2814	Major facilitator Superfamily
FZE25_RS09775	COG0640	Transcriptional regulator
FZE25_RS09780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FZE25_RS09790	COG0604	alcohol dehydrogenase
FZE25_RS09795	COG0493	'glutamate synthase
FZE25_RS09800	COG0067	glutamate synthase
FZE25_RS09800	COG0069	glutamate synthase activity
FZE25_RS09800	COG0070	glutamate synthase
FZE25_RS09805	COG0583	DNA-binding transcription factor activity
FZE25_RS09810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FZE25_RS09825	COG0300	oxidoreductase activity
FZE25_RS09830	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FZE25_RS09840	COG2814	Major facilitator Superfamily
FZE25_RS09845	COG1070	Carbohydrate kinase
FZE25_RS09850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FZE25_RS09855	COG0243	molybdopterin cofactor binding
FZE25_RS09885	COG5444	nuclease activity
FZE25_RS09890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZE25_RS09895	COG2207	Transcriptional regulator
FZE25_RS09895	COG0662	Cupin 2, conserved barrel domain protein
FZE25_RS09900	COG1309	transcriptional regulator
FZE25_RS09905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS09915	COG0640	Transcriptional regulator
FZE25_RS09920	COG0741	lytic transglycosylase activity
FZE25_RS09925	COG2322	membrane
FZE25_RS09940	COG1619	proteins homologs of microcin C7 resistance protein MccF
FZE25_RS09950	COG1388	LysM domain
FZE25_RS09950	COG3584	3D domain protein
FZE25_RS09955	COG0514	ATP-dependent DNA helicase (RecQ)
FZE25_RS09965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FZE25_RS09970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FZE25_RS09985	COG0071	Belongs to the small heat shock protein (HSP20) family
FZE25_RS10015	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS10020	COG1657	PFAM Prenyltransferase squalene oxidase
FZE25_RS10025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FZE25_RS10030	COG0733	neurotransmitter:sodium symporter activity
FZE25_RS10035	COG0385	Bile acid
FZE25_RS10040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS10045	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZE25_RS10055	COG4548	von Willebrand factor, type A
FZE25_RS10060	COG0714	Associated with various cellular activities
FZE25_RS10065	COG2032	superoxide dismutase activity
FZE25_RS10070	COG1388	LysM domain
FZE25_RS10070	COG0791	NLP P60 protein
FZE25_RS10075	COG1819	glycosyl
FZE25_RS10080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FZE25_RS10085	COG0534	Mate efflux family protein
FZE25_RS10090	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS10095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FZE25_RS10100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FZE25_RS10110	COG2962	Rard protein
FZE25_RS10125	COG1942	4-Oxalocrotonate Tautomerase
FZE25_RS10135	COG1733	regulation of RNA biosynthetic process
FZE25_RS10140	COG0778	Nitroreductase
FZE25_RS10145	COG0400	carboxylic ester hydrolase activity
FZE25_RS10150	COG0346	lactoylglutathione lyase activity
FZE25_RS10160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FZE25_RS10170	COG2723	6-phospho-beta-galactosidase activity
FZE25_RS10175	COG2188	Transcriptional regulator
FZE25_RS10180	COG0793	Belongs to the peptidase S41A family
FZE25_RS10180	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS10185	COG2226	methyltransferase
FZE25_RS10195	COG1876	peptidase activity
FZE25_RS10215	COG0671	phosphoesterase, PA-phosphatase related
FZE25_RS10245	COG1509	lysine 2,3-aminomutase activity
FZE25_RS10250	COG0456	acetyltransferase
FZE25_RS10255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZE25_RS10260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FZE25_RS10265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FZE25_RS10270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FZE25_RS10285	COG0456	acetyltransferase
FZE25_RS10290	COG0463	Glycosyl transferase, family 2
FZE25_RS10305	COG4641	Protein conserved in bacteria
FZE25_RS10315	COG1086	Polysaccharide biosynthesis protein
FZE25_RS10330	COG1846	Transcriptional regulator
FZE25_RS10335	COG4698	Protein conserved in bacteria
FZE25_RS10340	COG2755	lipolytic protein G-D-S-L family
FZE25_RS10345	COG1999	signal sequence binding
FZE25_RS10355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FZE25_RS10360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FZE25_RS10365	COG1272	protein, Hemolysin III
FZE25_RS10370	COG0204	Acyl-transferase
FZE25_RS10375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FZE25_RS10390	COG2521	methyltransferase
FZE25_RS10390	COG2136	Putative SAM-dependent methyltransferase
FZE25_RS10405	COG1413	lyase activity
FZE25_RS10410	COG1418	mRNA catabolic process
FZE25_RS10415	COG0386	Belongs to the glutathione peroxidase family
FZE25_RS10425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FZE25_RS10435	COG1278	Cold shock
FZE25_RS10455	COG0328	RNA-DNA hybrid ribonuclease activity
FZE25_RS10460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FZE25_RS10465	COG0328	RNA-DNA hybrid ribonuclease activity
FZE25_RS10475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FZE25_RS10490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FZE25_RS10500	COG1755	Isoprenylcysteine carboxyl methyltransferase
FZE25_RS10505	COG3424	synthase
FZE25_RS10530	COG1335	isochorismatase
FZE25_RS10540	COG2233	PERMEase
FZE25_RS10550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FZE25_RS10555	COG1199	ATP-dependent helicase activity
FZE25_RS10570	COG0116	Belongs to the methyltransferase superfamily
FZE25_RS10600	COG3359	exonuclease
FZE25_RS10605	COG1111	helicase
FZE25_RS10605	COG1205	dead DEAH box helicase
FZE25_RS10610	COG2190	(PTS) system
FZE25_RS10615	COG0071	Belongs to the small heat shock protein (HSP20) family
FZE25_RS10655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZE25_RS10655	COG4499	WXG100 protein secretion system (Wss), protein YukC
FZE25_RS10665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FZE25_RS10670	COG3935	DnaD domain protein
FZE25_RS10680	COG0436	Aminotransferase
FZE25_RS10685	COG5353	protein conserved in bacteria
FZE25_RS10695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FZE25_RS10695	COG1199	ATP-dependent helicase activity
FZE25_RS10725	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS10730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FZE25_RS10745	COG1694	Mazg nucleotide pyrophosphohydrolase
FZE25_RS10750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS10755	COG2140	Oxalate decarboxylase
FZE25_RS10765	COG4347	Protein of unknown function (DUF1405)
FZE25_RS10770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FZE25_RS10770	COG2010	Cytochrome c
FZE25_RS10775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FZE25_RS10780	COG0723	plastoquinol--plastocyanin reductase activity
FZE25_RS10795	COG0457	Tetratricopeptide repeat
FZE25_RS10805	COG0287	Prephenate dehydrogenase
FZE25_RS10840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FZE25_RS10845	COG4401	Chorismate mutase type I
FZE25_RS10860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FZE25_RS10865	COG0105	UTP biosynthetic process
FZE25_RS10870	COG0142	geranyltranstransferase activity
FZE25_RS10880	COG0142	geranyltranstransferase activity
FZE25_RS10895	COG0776	regulation of translation
FZE25_RS10900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FZE25_RS10940	COG0539	negative regulation of cytoplasmic translation
FZE25_RS10950	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FZE25_RS10955	COG2959	enzyme of heme biosynthesis
FZE25_RS10960	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS10960	COG3773	Cell wall hydrolase
FZE25_RS10965	COG2339	peptidase activity
FZE25_RS10970	COG0492	ferredoxin-NADP+ reductase activity
FZE25_RS10975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FZE25_RS10980	COG4862	establishment of competence for transformation
FZE25_RS10985	COG1408	metallophosphoesterase
FZE25_RS10995	COG1388	LysM domain
FZE25_RS11000	COG1266	CAAX protease self-immunity
FZE25_RS11005	COG0514	ATP-dependent DNA helicase (RecQ)
FZE25_RS11010	COG4955	Helix-turn-helix domain
FZE25_RS11015	COG1141	Ferredoxin
FZE25_RS11020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FZE25_RS11025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FZE25_RS11035	COG1595	DNA-templated transcription, initiation
FZE25_RS11040	COG5002	protein histidine kinase activity
FZE25_RS11045	COG0745	RESPONSE REGULATOR receiver
FZE25_RS11050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FZE25_RS11055	COG1333	cytochrome c biogenesis protein
FZE25_RS11060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS11065	COG1187	pseudouridine synthase activity
FZE25_RS11070	COG0700	Nucleoside recognition
FZE25_RS11075	COG2715	membrane protein required for spore maturation
FZE25_RS11080	COG1686	Belongs to the peptidase S11 family
FZE25_RS11105	COG1547	Domain of unknown function (DUF309)
FZE25_RS11115	COG0456	acetyltransferase
FZE25_RS11130	COG0307	riboflavin synthase, alpha
FZE25_RS11135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FZE25_RS11135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FZE25_RS11145	COG0681	Belongs to the peptidase S26 family
FZE25_RS11155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FZE25_RS11160	COG4086	secreted protein
FZE25_RS11165	COG0019	diaminopimelate decarboxylase activity
FZE25_RS11170	COG0697	spore germination
FZE25_RS11185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZE25_RS11205	COG1191	sigma factor activity
FZE25_RS11215	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS11220	COG1686	Belongs to the peptidase S11 family
FZE25_RS11225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FZE25_RS11230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FZE25_RS11235	COG4974	Belongs to the 'phage' integrase family
FZE25_RS11245	COG0735	belongs to the Fur family
FZE25_RS11250	COG1300	Membrane
FZE25_RS11265	COG0281	malic enzyme
FZE25_RS11270	COG1757	Na H antiporter
FZE25_RS11275	COG1027	Aspartate ammonia-lyase
FZE25_RS11280	COG0252	asparaginase activity
FZE25_RS11285	COG1396	sequence-specific DNA binding
FZE25_RS11290	COG1379	DNA repair
FZE25_RS11295	COG0494	nUDIX hydrolase
FZE25_RS11305	COG0667	Aldo Keto reductase
FZE25_RS11315	COG1073	alpha beta
FZE25_RS11325	COG4918	Iron-sulphur cluster biosynthesis
FZE25_RS11330	COG0456	acetyltransferase
FZE25_RS11330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FZE25_RS11335	COG2329	Antibiotic biosynthesis monooxygenase
FZE25_RS11340	COG0456	acetyltransferase
FZE25_RS11345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FZE25_RS11360	COG0628	permease
FZE25_RS11370	COG0346	lactoylglutathione lyase activity
FZE25_RS11380	COG3048	D-serine ammonia-lyase activity
FZE25_RS11385	COG0300	oxidoreductase activity
FZE25_RS11390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS11395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FZE25_RS11400	COG1024	Enoyl-CoA hydratase
FZE25_RS11405	COG3425	synthase
FZE25_RS11410	COG2124	cytochrome p450
FZE25_RS11415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS11415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS11415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11415	COG3321	synthase
FZE25_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11420	COG3321	synthase
FZE25_RS11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS11425	COG3321	synthase
FZE25_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11425	COG0300	oxidoreductase activity
FZE25_RS11430	COG0300	oxidoreductase activity
FZE25_RS11430	COG3321	synthase
FZE25_RS11430	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS11430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11435	COG3321	synthase
FZE25_RS11435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS11435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS11435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11440	COG3321	synthase
FZE25_RS11440	COG0300	oxidoreductase activity
FZE25_RS11440	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZE25_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS11445	COG3321	synthase
FZE25_RS11445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS11455	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS11470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FZE25_RS11470	COG2070	2-Nitropropane dioxygenase
FZE25_RS11480	COG0250	Participates in transcription elongation, termination and antitermination
FZE25_RS11505	COG0596	Alpha beta hydrolase
FZE25_RS11520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FZE25_RS11525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FZE25_RS11540	COG0706	membrane insertase activity
FZE25_RS11545	COG2195	Cleaves the N-terminal amino acid of tripeptides
FZE25_RS11550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FZE25_RS11555	COG0346	lactoylglutathione lyase activity
FZE25_RS11565	COG1376	ErfK ybiS ycfS ynhG family protein
FZE25_RS11570	COG4129	membrane
FZE25_RS11575	COG1126	abc transporter atp-binding protein
FZE25_RS11580	COG0765	amino acid transport
FZE25_RS11585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS11600	COG1597	lipid kinase activity
FZE25_RS11605	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZE25_RS11610	COG0022	dehydrogenase e1 component
FZE25_RS11615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FZE25_RS11620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FZE25_RS11625	COG3426	butyrate kinase activity
FZE25_RS11630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FZE25_RS11635	COG0280	phosphate acetyltransferase
FZE25_RS11640	COG3290	protein histidine kinase activity
FZE25_RS11640	COG3829	transcription factor binding
FZE25_RS11650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FZE25_RS11655	COG2079	MmgE PrpD family protein
FZE25_RS11660	COG0372	Belongs to the citrate synthase family
FZE25_RS11665	COG1960	acyl-CoA dehydrogenase activity
FZE25_RS11670	COG1250	3-hydroxyacyl-CoA dehydrogenase
FZE25_RS11675	COG0183	Belongs to the thiolase family
FZE25_RS11680	COG0584	glycerophosphoryl diester phosphodiesterase
FZE25_RS11685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS11705	COG1902	pentaerythritol trinitrate reductase activity
FZE25_RS11720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FZE25_RS11730	COG0745	RESPONSE REGULATOR receiver
FZE25_RS11735	COG0750	zinc metalloprotease
FZE25_RS11740	COG0497	DNA recombination
FZE25_RS11750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FZE25_RS11760	COG0142	geranyltranstransferase activity
FZE25_RS11770	COG1570	exodeoxyribonuclease VII activity
FZE25_RS11785	COG1302	Protein conserved in bacteria
FZE25_RS11790	COG0439	Biotin carboxylase
FZE25_RS11795	COG0511	ligase activity, forming carbon-carbon bonds
FZE25_RS11835	COG3854	ATPases associated with a variety of cellular activities
FZE25_RS11850	COG0006	proline dipeptidase activity
FZE25_RS11860	COG3872	metal-dependent enzyme
FZE25_RS11870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FZE25_RS11885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FZE25_RS11905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FZE25_RS11920	COG1396	sequence-specific DNA binding
FZE25_RS11930	COG0681	Belongs to the peptidase S26 family
FZE25_RS11955	COG4940	Competence protein ComGF
FZE25_RS11965	COG4970	Tfp pilus assembly protein FimT
FZE25_RS11970	COG4537	Required for transformation and DNA binding
FZE25_RS11975	COG1459	type II secretion system
FZE25_RS11980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FZE25_RS11985	COG0598	Magnesium transport protein CorA
FZE25_RS11990	COG1253	flavin adenine dinucleotide binding
FZE25_RS11995	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS12005	COG1393	Belongs to the ArsC family
FZE25_RS12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS12025	COG0011	TIGRFAM Protein of
FZE25_RS12035	COG2866	Carboxypeptidase
FZE25_RS12040	COG1940	carbohydrate kinase activity
FZE25_RS12045	COG4483	Protein conserved in bacteria
FZE25_RS12050	COG1757	Na H antiporter
FZE25_RS12060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FZE25_RS12075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FZE25_RS12080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FZE25_RS12085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FZE25_RS12090	COG0581	inorganic phosphate transmembrane transporter activity
FZE25_RS12095	COG0573	inorganic phosphate transmembrane transporter activity
FZE25_RS12100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FZE25_RS12105	COG0768	penicillin binding
FZE25_RS12110	COG0477	Major facilitator Superfamily
FZE25_RS12115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FZE25_RS12120	COG2839	Protein conserved in bacteria
FZE25_RS12125	COG5521	maltodextrose utilization protein MalA
FZE25_RS12130	COG1388	LysM domain
FZE25_RS12145	COG4709	membrane
FZE25_RS12150	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FZE25_RS12155	COG0735	belongs to the Fur family
FZE25_RS12160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS12175	COG0513	Belongs to the DEAD box helicase family
FZE25_RS12190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FZE25_RS12195	COG2384	SAM-dependent methyltransferase
FZE25_RS12200	COG2010	Cytochrome c
FZE25_RS12205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FZE25_RS12210	COG0358	DNA primase activity
FZE25_RS12225	COG0517	IMP dehydrogenase activity
FZE25_RS12230	COG0751	glycine-tRNA ligase activity
FZE25_RS12250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FZE25_RS12255	COG0295	cytidine deaminase activity
FZE25_RS12260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FZE25_RS12270	COG1480	7TM receptor with intracellular HD hydrolase
FZE25_RS12275	COG1702	phosphate starvation-inducible protein PhoH
FZE25_RS12280	COG0561	phosphatase activity
FZE25_RS12295	COG4864	UPF0365 protein
FZE25_RS12300	COG1030	water channel activity
FZE25_RS12305	COG1610	YqeY-like protein
FZE25_RS12315	COG1283	sodium-dependent phosphate transmembrane transporter activity
FZE25_RS12320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FZE25_RS12325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FZE25_RS12355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FZE25_RS12370	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS12385	COG1466	dna polymerase III delta subunit
FZE25_RS12400	COG2333	competence protein COMEC
FZE25_RS12400	COG0658	competence protein
FZE25_RS12405	COG2131	deaminase
FZE25_RS12410	COG1555	photosystem II stabilization
FZE25_RS12410	COG1596	polysaccharide export
FZE25_RS12415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FZE25_RS12420	COG2226	methyltransferase
FZE25_RS12425	COG0799	negative regulation of ribosome biogenesis
FZE25_RS12430	COG1713	HD superfamily hydrolase involved in NAD metabolism
FZE25_RS12440	COG1534	Rna-binding protein
FZE25_RS12445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FZE25_RS12450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FZE25_RS12455	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FZE25_RS12465	COG2755	lipolytic protein G-D-S-L family
FZE25_RS12475	COG0398	Pfam SNARE associated Golgi protein
FZE25_RS12515	COG5444	nuclease activity
FZE25_RS12520	COG4282	regulation of fungal-type cell wall biogenesis
FZE25_RS12535	COG3708	Transcriptional regulator
FZE25_RS12535	COG2207	Transcriptional regulator
FZE25_RS12545	COG0563	adenylate kinase activity
FZE25_RS12550	COG2814	Major facilitator Superfamily
FZE25_RS12560	COG0456	acetyltransferase
FZE25_RS12565	COG2318	DinB family
FZE25_RS12575	COG0561	phosphatase activity
FZE25_RS12580	COG0561	phosphatase activity
FZE25_RS12590	COG1482	cell wall glycoprotein biosynthetic process
FZE25_RS12595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZE25_RS12595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZE25_RS12595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS12600	COG3711	transcriptional antiterminator
FZE25_RS12600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS12610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FZE25_RS12615	COG0583	DNA-binding transcription factor activity
FZE25_RS12620	COG2814	Major facilitator Superfamily
FZE25_RS12625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZE25_RS12625	COG2124	cytochrome p450
FZE25_RS12630	COG1309	transcriptional regulator
FZE25_RS12635	COG2226	methyltransferase
FZE25_RS12650	COG2116	formate transmembrane transporter activity
FZE25_RS12655	COG5609	conserved protein (DUF2294)
FZE25_RS12660	COG3383	formate dehydrogenase (NAD+) activity
FZE25_RS12665	COG2427	Protein of unknown function (DUF1641)
FZE25_RS12675	COG0626	cystathionine gamma-synthase activity
FZE25_RS12680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FZE25_RS12705	COG0768	penicillin binding
FZE25_RS12720	COG0826	peptidase U32
FZE25_RS12725	COG0826	peptidase U32
FZE25_RS12730	COG4122	O-methyltransferase activity
FZE25_RS12735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FZE25_RS12760	COG0628	permease
FZE25_RS12765	COG1126	abc transporter atp-binding protein
FZE25_RS12770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS12775	COG0765	amino acid transport
FZE25_RS12780	COG0765	amino acid transport
FZE25_RS12795	COG3881	PFAM PRC-barrel domain
FZE25_RS12800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FZE25_RS12805	COG0457	Tetratricopeptide repeat
FZE25_RS12815	COG1104	cysteine desulfurase activity
FZE25_RS12820	COG1959	2 iron, 2 sulfur cluster binding
FZE25_RS12825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FZE25_RS12830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FZE25_RS12850	COG4991	sh3 domain protein
FZE25_RS12850	COG3103	Sh3 type 3 domain protein
FZE25_RS12850	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS12860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FZE25_RS12870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FZE25_RS12870	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FZE25_RS12875	COG5416	Lipopolysaccharide assembly protein A domain
FZE25_RS12880	COG0490	domain, Protein
FZE25_RS12885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FZE25_RS12885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FZE25_RS12895	COG2244	polysaccharide biosynthetic process
FZE25_RS12900	COG2323	membrane
FZE25_RS12910	COG1862	Preprotein translocase
FZE25_RS12955	COG1388	LysM domain
FZE25_RS12965	COG0157	Belongs to the NadC ModD family
FZE25_RS12970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FZE25_RS12975	COG1104	cysteine desulfurase activity
FZE25_RS12980	COG1827	regulation of RNA biosynthetic process
FZE25_RS12985	COG0077	Prephenate dehydratase
FZE25_RS13000	COG3290	protein histidine kinase activity
FZE25_RS13005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FZE25_RS13010	COG2868	ribosomal protein
FZE25_RS13020	COG1994	Peptidase M50
FZE25_RS13025	COG0739	heme binding
FZE25_RS13030	COG2894	cell division
FZE25_RS13040	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FZE25_RS13050	COG1077	Cell shape determining protein MreB Mrl
FZE25_RS13070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FZE25_RS13075	COG0285	dihydrofolate synthase activity
FZE25_RS13080	COG0525	valine-tRNA ligase activity
FZE25_RS13090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FZE25_RS13095	COG1388	LysM domain
FZE25_RS13105	COG0113	porphobilinogen synthase activity
FZE25_RS13110	COG1587	Uroporphyrinogen-III synthase
FZE25_RS13120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FZE25_RS13140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FZE25_RS13145	COG1067	ATP-dependent peptidase activity
FZE25_RS13145	COG0470	DNA polymerase III
FZE25_RS13160	COG1477	protein flavinylation
FZE25_RS13160	COG0457	Tetratricopeptide repeat
FZE25_RS13175	COG0473	3-isopropylmalate dehydrogenase activity
FZE25_RS13190	COG0440	acetolactate synthase activity
FZE25_RS13195	COG0028	Belongs to the TPP enzyme family
FZE25_RS13220	COG0622	Phosphoesterase
FZE25_RS13225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FZE25_RS13235	COG5401	PFAM Sporulation and spore germination
FZE25_RS13245	COG1846	Transcriptional regulator
FZE25_RS13250	COG2197	response regulator
FZE25_RS13255	COG0824	Thioesterase
FZE25_RS13260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FZE25_RS13265	COG1053	succinate dehydrogenase
FZE25_RS13270	COG2009	succinate dehydrogenase
FZE25_RS13275	COG1719	4-vinyl reductase, 4VR
FZE25_RS13280	COG0527	aspartate kinase activity
FZE25_RS13295	COG3118	belongs to the thioredoxin family
FZE25_RS13300	COG3534	alpha-L-arabinofuranosidase
FZE25_RS13305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FZE25_RS13310	COG2086	electron transfer activity
FZE25_RS13315	COG1024	Enoyl-CoA hydratase
FZE25_RS13320	COG1309	transcriptional regulator
FZE25_RS13325	COG0318	PFAM AMP-dependent synthetase and ligase
FZE25_RS13335	COG3766	membrane
FZE25_RS13345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FZE25_RS13345	COG1796	DNA polymerase
FZE25_RS13350	COG1286	toxin biosynthetic process
FZE25_RS13365	COG0072	phenylalanine-tRNA ligase activity
FZE25_RS13365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZE25_RS13370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FZE25_RS13375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FZE25_RS13385	COG3835	regulator
FZE25_RS13390	COG0277	FAD linked oxidase domain protein
FZE25_RS13395	COG0247	lactate metabolic process
FZE25_RS13400	COG1966	Carbon starvation protein
FZE25_RS13405	COG3534	alpha-L-arabinofuranosidase
FZE25_RS13410	COG0395	ABC-type sugar transport system, permease component
FZE25_RS13415	COG1175	transmembrane transport
FZE25_RS13420	COG1653	transport
FZE25_RS13430	COG0647	UMP catabolic process
FZE25_RS13435	COG0235	Class ii aldolase
FZE25_RS13440	COG1069	ribulokinase activity
FZE25_RS13445	COG2160	L-arabinose isomerase activity
FZE25_RS13450	COG3507	Belongs to the glycosyl hydrolase 43 family
FZE25_RS13455	COG1363	Peptidase, m42
FZE25_RS13465	COG3326	Membrane
FZE25_RS13470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FZE25_RS13480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FZE25_RS13485	COG1346	cytolysis
FZE25_RS13490	COG1380	Effector of murein hydrolase LrgA
FZE25_RS13495	COG3279	Response regulator of the LytR AlgR family
FZE25_RS13500	COG3275	phosphorelay sensor kinase activity
FZE25_RS13505	COG1011	Hydrolase
FZE25_RS13520	COG0398	Pfam SNARE associated Golgi protein
FZE25_RS13525	COG1484	DNA-dependent DNA replication
FZE25_RS13530	COG3611	Membrane attachment protein
FZE25_RS13545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FZE25_RS13550	COG1733	regulation of RNA biosynthetic process
FZE25_RS13555	COG2814	Major facilitator Superfamily
FZE25_RS13560	COG0656	L-ascorbic acid biosynthetic process
FZE25_RS13565	COG0237	dephospho-CoA kinase activity
FZE25_RS13570	COG1971	Probably functions as a manganese efflux pump
FZE25_RS13575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FZE25_RS13580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FZE25_RS13580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FZE25_RS13585	COG5002	protein histidine kinase activity
FZE25_RS13590	COG0745	RESPONSE REGULATOR receiver
FZE25_RS13600	COG0538	isocitrate dehydrogenase activity
FZE25_RS13605	COG0372	Belongs to the citrate synthase family
FZE25_RS13630	COG0628	permease
FZE25_RS13635	COG3030	protein affecting phage T7 exclusion by the F plasmid
FZE25_RS13640	COG0469	pyruvate kinase activity
FZE25_RS13660	COG0281	malic enzyme
FZE25_RS13665	COG0587	DNA-directed DNA polymerase activity
FZE25_RS13685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FZE25_RS13695	COG4109	DRTGG domain
FZE25_RS13705	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS13725	COG0521	Mo-molybdopterin cofactor biosynthetic process
FZE25_RS13740	COG0827	DNA restriction-modification system
FZE25_RS13745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FZE25_RS13750	COG3874	Sporulation protein YtfJ
FZE25_RS13760	COG1714	RDD family
FZE25_RS13765	COG0616	signal peptide processing
FZE25_RS13770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FZE25_RS13775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FZE25_RS13780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FZE25_RS13795	COG1104	cysteine desulfurase activity
FZE25_RS13800	COG1114	Component of the transport system for branched-chain amino acids
FZE25_RS13810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FZE25_RS13815	COG1309	transcriptional regulator
FZE25_RS13820	COG1956	GAF domain-containing protein
FZE25_RS13825	COG2199	diguanylate cyclase activity
FZE25_RS13825	COG2203	Gaf domain
FZE25_RS13840	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS13880	COG1017	nitric oxide dioxygenase activity
FZE25_RS13880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FZE25_RS13895	COG0693	protein deglycase activity
FZE25_RS13910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FZE25_RS13915	COG1378	Sugar-specific transcriptional regulator TrmB
FZE25_RS13935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FZE25_RS13940	COG0454	-acetyltransferase
FZE25_RS13945	COG0517	IMP dehydrogenase activity
FZE25_RS13950	COG0123	including yeast histone deacetylase and acetoin utilization protein
FZE25_RS13955	COG1360	Flagellar Motor Protein
FZE25_RS13960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FZE25_RS13965	COG1609	Transcriptional regulator
FZE25_RS13970	COG1605	Chorismate mutase
FZE25_RS13970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FZE25_RS13975	COG3118	belongs to the thioredoxin family
FZE25_RS13980	COG4980	gas vesicle protein
FZE25_RS13985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FZE25_RS13995	COG1674	ftsk spoiiie
FZE25_RS14000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZE25_RS14010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS14020	COG1363	Peptidase, m42
FZE25_RS14025	COG5584	Small secreted protein
FZE25_RS14030	COG0281	malic enzyme
FZE25_RS14035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZE25_RS14050	COG0510	thiamine kinase activity
FZE25_RS14055	COG1597	lipid kinase activity
FZE25_RS14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FZE25_RS14070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FZE25_RS14075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZE25_RS14080	COG2252	PERMEase
FZE25_RS14085	COG4473	ABC transporter
FZE25_RS14090	COG1131	(ABC) transporter
FZE25_RS14095	COG1349	DNA-binding transcription factor activity
FZE25_RS14100	COG1187	pseudouridine synthase activity
FZE25_RS14105	COG2244	polysaccharide biosynthetic process
FZE25_RS14110	COG2081	HI0933 family
FZE25_RS14115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FZE25_RS14125	COG1609	Transcriptional regulator
FZE25_RS14130	COG1653	transport
FZE25_RS14135	COG1175	transmembrane transport
FZE25_RS14140	COG0395	ABC-type sugar transport system, permease component
FZE25_RS14145	COG1486	melibiose metabolic process
FZE25_RS14155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FZE25_RS14170	COG2202	Pas domain
FZE25_RS14170	COG1366	Belongs to the anti-sigma-factor antagonist family
FZE25_RS14175	COG2814	Major facilitator Superfamily
FZE25_RS14180	COG5522	Integral membrane protein (intg_mem_TP0381)
FZE25_RS14185	COG0577	efflux transmembrane transporter activity
FZE25_RS14190	COG1136	(ABC) transporter
FZE25_RS14195	COG2205	protein histidine kinase activity
FZE25_RS14200	COG0745	RESPONSE REGULATOR receiver
FZE25_RS14205	COG0577	efflux transmembrane transporter activity
FZE25_RS14210	COG1136	(ABC) transporter
FZE25_RS14230	COG1131	(ABC) transporter
FZE25_RS14235	COG1725	Transcriptional regulator
FZE25_RS14245	COG1242	4 iron, 4 sulfur cluster binding
FZE25_RS14250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FZE25_RS14260	COG0584	glycerophosphoryl diester phosphodiesterase
FZE25_RS14270	COG2267	carboxylic ester hydrolase activity
FZE25_RS14275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FZE25_RS14280	COG1113	amino acid transport
FZE25_RS14285	COG0367	asparagine synthase
FZE25_RS14305	COG1506	peptidase
FZE25_RS14310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FZE25_RS14315	COG1116	anion transmembrane transporter activity
FZE25_RS14320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FZE25_RS14325	COG0494	nUDIX hydrolase
FZE25_RS14330	COG4824	toxin secretion phage lysis holin
FZE25_RS14335	COG0783	Belongs to the Dps family
FZE25_RS14360	COG0288	reversible hydration of carbon dioxide
FZE25_RS14370	COG1271	oxidase subunit
FZE25_RS14375	COG1294	oxidase, subunit
FZE25_RS14390	COG4948	Mandelate Racemase Muconate Lactonizing
FZE25_RS14400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FZE25_RS14405	COG0596	Alpha beta hydrolase
FZE25_RS14415	COG1169	isochorismate synthase
FZE25_RS14420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FZE25_RS14425	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FZE25_RS14550	COG3859	Proton-coupled thiamine transporter YuaJ
FZE25_RS14555	COG2268	Band 7 protein
FZE25_RS14560	COG1585	Membrane protein implicated in regulation of membrane protease activity
FZE25_RS14565	COG2318	DinB family
FZE25_RS14575	COG1454	alcohol dehydrogenase
FZE25_RS14580	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS14585	COG1510	regulation of RNA biosynthetic process
FZE25_RS14595	COG0569	domain protein
FZE25_RS14600	COG1705	Flagellar rod assembly protein muramidase FlgJ
FZE25_RS14605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FZE25_RS14605	COG1017	nitric oxide dioxygenase activity
FZE25_RS14630	COG0628	permease
FZE25_RS14635	COG0673	inositol 2-dehydrogenase activity
FZE25_RS14640	COG0693	protein deglycase activity
FZE25_RS14645	COG0840	transmembrane signaling receptor activity
FZE25_RS14650	COG0840	transmembrane signaling receptor activity
FZE25_RS14655	COG0840	transmembrane signaling receptor activity
FZE25_RS14660	COG0840	transmembrane signaling receptor activity
FZE25_RS14675	COG2070	2-Nitropropane dioxygenase
FZE25_RS14680	COG0432	Pfam Uncharacterised protein family UPF0047
FZE25_RS14685	COG0366	Alpha amylase catalytic
FZE25_RS14690	COG1253	flavin adenine dinucleotide binding
FZE25_RS14695	COG2738	Putative neutral zinc metallopeptidase
FZE25_RS14710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FZE25_RS14740	COG1335	isochorismatase
FZE25_RS14745	COG1979	alcohol dehydrogenase
FZE25_RS14750	COG1979	alcohol dehydrogenase
FZE25_RS14755	COG2155	Conserved Protein
FZE25_RS14760	COG1098	S1 RNA binding domain
FZE25_RS14765	COG0436	Aminotransferase
FZE25_RS14770	COG1522	sequence-specific DNA binding
FZE25_RS14775	COG2267	carboxylic ester hydrolase activity
FZE25_RS14785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FZE25_RS14790	COG2205	protein histidine kinase activity
FZE25_RS14800	COG5018	Exonuclease
FZE25_RS14805	COG2814	Major facilitator Superfamily
FZE25_RS14810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZE25_RS14815	COG3011	Protein conserved in bacteria
FZE25_RS14825	COG3290	protein histidine kinase activity
FZE25_RS14830	COG4565	transcriptional regulatory protein
FZE25_RS14835	COG1744	ABC transporter substrate-binding protein PnrA-like
FZE25_RS14840	COG3845	ABC transporter
FZE25_RS14845	COG4603	Belongs to the binding-protein-dependent transport system permease family
FZE25_RS14850	COG1079	Belongs to the binding-protein-dependent transport system permease family
FZE25_RS14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FZE25_RS14860	COG2111	Na H antiporter
FZE25_RS14865	COG2111	Na H antiporter
FZE25_RS14870	COG1006	Multisubunit Na H antiporter MnhC subunit
FZE25_RS14875	COG0651	ATP synthesis coupled electron transport
FZE25_RS14880	COG1863	multisubunit Na H antiporter MnhE subunit
FZE25_RS14885	COG2212	antiporter activity
FZE25_RS14890	COG1320	monovalent cation:proton antiporter activity
FZE25_RS14895	COG2050	protein possibly involved in aromatic compounds catabolism
FZE25_RS14900	COG2197	response regulator
FZE25_RS14905	COG4585	Histidine kinase
FZE25_RS14915	COG0142	geranyltranstransferase activity
FZE25_RS14935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FZE25_RS14940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FZE25_RS14945	COG1335	isochorismatase
FZE25_RS14950	COG5506	Protein of unknown function (DUF1694)
FZE25_RS14965	COG0628	permease
FZE25_RS14975	COG1418	mRNA catabolic process
FZE25_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS14990	COG1511	domain protein
FZE25_RS14995	COG1674	ftsk spoiiie
FZE25_RS14995	COG0433	COG0433 Predicted ATPase
FZE25_RS15000	COG4499	WXG100 protein secretion system (Wss), protein YukC
FZE25_RS15005	COG5417	Belongs to the EsaB family
FZE25_RS15010	COG4842	Belongs to the WXG100 family
FZE25_RS15015	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FZE25_RS15015	COG2508	Transcriptional regulator
FZE25_RS15020	COG0686	Belongs to the AlaDH PNT family
FZE25_RS15025	COG5634	Uncharacterized conserved protein (DUF2278)
FZE25_RS15035	COG3251	PFAM MbtH domain protein
FZE25_RS15040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FZE25_RS15045	COG1535	isochorismatase
FZE25_RS15045	COG3433	isochorismatase activity
FZE25_RS15050	COG1021	2,3-dihydroxybenzoate-AMP ligase
FZE25_RS15055	COG1169	isochorismate synthase
FZE25_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS15065	COG2819	hydrolase of the alpha beta superfamily
FZE25_RS15070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FZE25_RS15075	COG1268	BioY protein
FZE25_RS15080	COG2056	Na+-H+ antiporter family
FZE25_RS15090	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FZE25_RS15095	COG3584	3D domain protein
FZE25_RS15110	COG1252	NADH dehydrogenase
FZE25_RS15140	COG1131	(ABC) transporter
FZE25_RS15160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FZE25_RS15165	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FZE25_RS15170	COG0316	Belongs to the HesB IscA family
FZE25_RS15180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FZE25_RS15190	COG1252	NADH dehydrogenase
FZE25_RS15195	COG4837	Protein of unknown function (DUF1462)
FZE25_RS15200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FZE25_RS15205	COG1506	peptidase
FZE25_RS15205	COG4946	Tricorn protease homolog
FZE25_RS15205	COG0823	Involved in the tonB-independent uptake of proteins
FZE25_RS15215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FZE25_RS15220	COG0460	homoserine dehydrogenase
FZE25_RS15225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FZE25_RS15230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FZE25_RS15235	COG0647	UMP catabolic process
FZE25_RS15240	COG2445	Protein of unknown function DUF86
FZE25_RS15245	COG4470	Protein conserved in bacteria
FZE25_RS15260	COG0739	heme binding
FZE25_RS15270	COG0737	Belongs to the 5'-nucleotidase family
FZE25_RS15275	COG0730	response to heat
FZE25_RS15280	COG1801	Protein of unknown function DUF72
FZE25_RS15295	COG2508	Transcriptional regulator
FZE25_RS15315	COG2814	Major facilitator Superfamily
FZE25_RS15320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FZE25_RS15325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZE25_RS15330	COG2356	endonuclease I
FZE25_RS15335	COG3842	ATPase activity
FZE25_RS15340	COG2188	Transcriptional regulator
FZE25_RS15345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FZE25_RS15350	COG0395	ABC-type sugar transport system, permease component
FZE25_RS15355	COG1175	transmembrane transport
FZE25_RS15360	COG1653	transport
FZE25_RS15365	COG2222	sugar isomerase
FZE25_RS15370	COG0789	Transcriptional regulator
FZE25_RS15395	COG0322	excinuclease ABC activity
FZE25_RS15400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZE25_RS15405	COG2226	methyltransferase
FZE25_RS15420	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS15425	COG0719	Fe-S assembly protein
FZE25_RS15430	COG0822	iron-sulfur transferase activity
FZE25_RS15435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FZE25_RS15440	COG0719	Fe-S assembly protein
FZE25_RS15445	COG0396	ATPase activity
FZE25_RS15455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FZE25_RS15460	COG1464	Belongs to the NlpA lipoprotein family
FZE25_RS15465	COG2011	ABC-type metal ion transport system permease component
FZE25_RS15470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FZE25_RS15480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZE25_RS15485	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FZE25_RS15500	COG1393	Belongs to the ArsC family
FZE25_RS15505	COG1960	acyl-CoA dehydrogenase activity
FZE25_RS15510	COG0183	Belongs to the thiolase family
FZE25_RS15515	COG1250	3-hydroxyacyl-CoA dehydrogenase
FZE25_RS15515	COG1024	Enoyl-CoA hydratase
FZE25_RS15535	COG5577	PFAM Coat F domain
FZE25_RS15540	COG1846	Transcriptional regulator
FZE25_RS15545	COG0477	Major facilitator Superfamily
FZE25_RS15550	COG0583	DNA-binding transcription factor activity
FZE25_RS15570	COG1120	ATPase activity
FZE25_RS15585	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS15590	COG0783	Belongs to the Dps family
FZE25_RS15595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZE25_RS15605	COG0745	RESPONSE REGULATOR receiver
FZE25_RS15610	COG2205	protein histidine kinase activity
FZE25_RS15610	COG2770	Histidine kinase
FZE25_RS15620	COG1309	transcriptional regulator
FZE25_RS15625	COG0114	fumarate hydratase activity
FZE25_RS15635	COG0697	spore germination
FZE25_RS15640	COG0814	amino acid
FZE25_RS15650	COG2197	response regulator
FZE25_RS15655	COG4585	Histidine kinase
FZE25_RS15660	COG4758	membrane
FZE25_RS15665	COG3595	metallopeptidase activity
FZE25_RS15670	COG1842	Phage shock protein A
FZE25_RS15675	COG4758	membrane
FZE25_RS15680	COG2814	Major facilitator Superfamily
FZE25_RS15685	COG2096	Adenosyltransferase
FZE25_RS15690	COG1120	ATPase activity
FZE25_RS15695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS15700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FZE25_RS15705	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS15710	COG3386	PFAM SMP-30 Gluconolaconase
FZE25_RS15715	COG2205	protein histidine kinase activity
FZE25_RS15720	COG0745	RESPONSE REGULATOR receiver
FZE25_RS15730	COG1191	sigma factor activity
FZE25_RS15740	COG2140	Oxalate decarboxylase
FZE25_RS15750	COG1120	ATPase activity
FZE25_RS15755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS15760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS15765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FZE25_RS15770	COG0531	amino acid
FZE25_RS15785	COG1988	membrane-bound metal-dependent
FZE25_RS15790	COG1368	sulfuric ester hydrolase activity
FZE25_RS15795	COG1910	domain protein
FZE25_RS15800	COG0725	ABC transporter, periplasmic molybdate-binding protein
FZE25_RS15805	COG4149	molybdate abc transporter
FZE25_RS15810	COG2197	response regulator
FZE25_RS15815	COG3850	Histidine kinase
FZE25_RS15820	COG1131	(ABC) transporter
FZE25_RS15830	COG0842	Transport permease protein
FZE25_RS15835	COG0656	L-ascorbic acid biosynthetic process
FZE25_RS15860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZE25_RS15865	COG3973	AAA domain
FZE25_RS15870	COG2860	membrane
FZE25_RS15880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FZE25_RS15885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FZE25_RS15890	COG2217	Heavy metal translocating P-type atpase
FZE25_RS15895	COG2217	Heavy metal translocating P-type atpase
FZE25_RS15900	COG2608	mercury ion transmembrane transporter activity
FZE25_RS15905	COG1937	Protein conserved in bacteria
FZE25_RS15910	COG0673	inositol 2-dehydrogenase activity
FZE25_RS15930	COG2814	Major facilitator Superfamily
FZE25_RS15945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS15950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FZE25_RS15955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS15960	COG1126	abc transporter atp-binding protein
FZE25_RS15965	COG0765	amino acid transport
FZE25_RS15970	COG0765	amino acid transport
FZE25_RS15975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS15980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZE25_RS15985	COG0454	-acetyltransferase
FZE25_RS15990	COG0583	DNA-binding transcription factor activity
FZE25_RS15995	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS16000	COG2732	(Barnase) inhibitor
FZE25_RS16015	COG0557	exoribonuclease II activity
FZE25_RS16020	COG1647	Serine aminopeptidase, S33
FZE25_RS16025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FZE25_RS16030	COG1476	TRANSCRIPTIONal
FZE25_RS16035	COG1396	sequence-specific DNA binding
FZE25_RS16040	COG1396	sequence-specific DNA binding
FZE25_RS16045	COG1733	regulation of RNA biosynthetic process
FZE25_RS16070	COG1131	(ABC) transporter
FZE25_RS16075	COG1174	glycine betaine transport
FZE25_RS16080	COG1732	Glycine betaine
FZE25_RS16085	COG1174	glycine betaine transport
FZE25_RS16090	COG1125	glycine betaine transport
FZE25_RS16090	COG0517	IMP dehydrogenase activity
FZE25_RS16095	COG1510	regulation of RNA biosynthetic process
FZE25_RS16100	COG1174	glycine betaine transport
FZE25_RS16105	COG1732	Glycine betaine
FZE25_RS16110	COG1174	glycine betaine transport
FZE25_RS16115	COG1125	glycine betaine transport
FZE25_RS16115	COG0517	IMP dehydrogenase activity
FZE25_RS16120	COG1510	regulation of RNA biosynthetic process
FZE25_RS16125	COG2095	MarC family integral membrane protein
FZE25_RS16130	COG3064	Membrane
FZE25_RS16135	COG4640	response to antibiotic
FZE25_RS16140	COG0456	acetyltransferase
FZE25_RS16155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FZE25_RS16170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FZE25_RS16175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZE25_RS16180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FZE25_RS16190	COG2234	aminopeptidase activity
FZE25_RS16210	COG0126	phosphoglycerate kinase activity
FZE25_RS16220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FZE25_RS16225	COG2390	Transcriptional regulator
FZE25_RS16230	COG2814	Major facilitator Superfamily
FZE25_RS16235	COG1609	Transcriptional regulator
FZE25_RS16240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS16250	COG0583	DNA-binding transcription factor activity
FZE25_RS16255	COG0697	spore germination
FZE25_RS16260	COG1113	amino acid transport
FZE25_RS16265	COG1737	Transcriptional regulator
FZE25_RS16270	COG1070	Carbohydrate kinase
FZE25_RS16295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS16300	COG2186	Transcriptional regulator
FZE25_RS16305	COG1620	l-lactate permease
FZE25_RS16310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FZE25_RS16320	COG5039	Polysaccharide pyruvyl transferase
FZE25_RS16325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FZE25_RS16330	COG0110	maltose O-acetyltransferase activity
FZE25_RS16335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FZE25_RS16340	COG2244	polysaccharide biosynthetic process
FZE25_RS16345	COG1216	Glycosyl transferase, family 2
FZE25_RS16350	COG5039	Polysaccharide pyruvyl transferase
FZE25_RS16355	COG1216	Glycosyl transferase, family 2
FZE25_RS16365	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS16370	COG1215	transferase activity, transferring glycosyl groups
FZE25_RS16375	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS16380	COG1086	Polysaccharide biosynthesis protein
FZE25_RS16385	COG0489	protein tyrosine kinase activity
FZE25_RS16390	COG3944	biosynthesis protein
FZE25_RS16395	COG1396	sequence-specific DNA binding
FZE25_RS16400	COG2272	Belongs to the type-B carboxylesterase lipase family
FZE25_RS16410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FZE25_RS16415	COG2364	Membrane
FZE25_RS16420	COG0456	acetyltransferase
FZE25_RS16425	COG3479	Phenolic acid decarboxylase
FZE25_RS16480	COG2223	nitrite transmembrane transporter activity
FZE25_RS16485	COG1609	Transcriptional regulator
FZE25_RS16495	COG0583	DNA-binding transcription factor activity
FZE25_RS16500	COG2828	Protein conserved in bacteria
FZE25_RS16505	COG2814	Major facilitator Superfamily
FZE25_RS16505	COG0477	Major facilitator Superfamily
FZE25_RS16510	COG1611	Belongs to the LOG family
FZE25_RS16515	COG1694	Mazg nucleotide pyrophosphohydrolase
FZE25_RS16520	COG0659	secondary active sulfate transmembrane transporter activity
FZE25_RS16525	COG0288	reversible hydration of carbon dioxide
FZE25_RS16535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FZE25_RS16540	COG4290	ribonuclease
FZE25_RS16545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FZE25_RS16550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS16560	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FZE25_RS16570	COG1051	belongs to the nudix hydrolase family
FZE25_RS16575	COG0492	ferredoxin-NADP+ reductase activity
FZE25_RS16580	COG0791	NLP P60 protein
FZE25_RS16580	COG3883	PFAM NLP P60 protein
FZE25_RS16585	COG0457	Tetratricopeptide repeat
FZE25_RS16590	COG5002	protein histidine kinase activity
FZE25_RS16595	COG0745	RESPONSE REGULATOR receiver
FZE25_RS16600	COG1132	(ABC) transporter
FZE25_RS16605	COG0140	phosphoribosyl-ATP diphosphatase activity
FZE25_RS16605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FZE25_RS16630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FZE25_RS16645	COG4990	cell redox homeostasis
FZE25_RS16650	COG0110	maltose O-acetyltransferase activity
FZE25_RS16670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FZE25_RS16680	COG2188	Transcriptional regulator
FZE25_RS16685	COG1309	transcriptional regulator
FZE25_RS16690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FZE25_RS16695	COG1950	PFAM Membrane protein of
FZE25_RS16700	COG1983	PspC domain protein
FZE25_RS16705	COG3595	metallopeptidase activity
FZE25_RS16720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FZE25_RS16730	COG4897	Protein conserved in bacteria
FZE25_RS16735	COG3848	Pyruvate phosphate dikinase
FZE25_RS16735	COG0574	Belongs to the PEP-utilizing enzyme family
FZE25_RS16740	COG1309	transcriptional regulator
FZE25_RS16745	COG2814	Major facilitator Superfamily
FZE25_RS16785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZE25_RS16795	COG0793	Belongs to the peptidase S41A family
FZE25_RS16795	COG3409	Peptidoglycan-binding domain 1 protein
FZE25_RS16800	COG3420	alginic acid biosynthetic process
FZE25_RS16805	COG2177	Part of the ABC transporter FtsEX involved in
FZE25_RS16810	COG2884	Cell division ATP-binding protein ftsE
FZE25_RS16815	COG2010	Cytochrome c
FZE25_RS16820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS16835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FZE25_RS16850	COG1516	flagellar protein fliS
FZE25_RS16855	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FZE25_RS16860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FZE25_RS16880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FZE25_RS16885	COG4786	Flagellar basal body rod
FZE25_RS16885	COG1256	bacterial-type flagellum assembly
FZE25_RS16890	COG3418	PFAM FlgN family protein
FZE25_RS16895	COG2747	anti-sigma28 factor FlgM
FZE25_RS16905	COG1040	competence protein
FZE25_RS16915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FZE25_RS16920	COG1307	EDD domain protein, DegV family
FZE25_RS16925	COG2197	response regulator
FZE25_RS16930	COG4585	Histidine kinase
FZE25_RS16935	COG1739	Uncharacterized protein family UPF0029
FZE25_RS16940	COG1316	TRANSCRIPTIONal
FZE25_RS16945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FZE25_RS16950	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS16955	COG1215	transferase activity, transferring glycosyl groups
FZE25_RS16960	COG3206	protein involved in exopolysaccharide biosynthesis
FZE25_RS16965	COG3307	-O-antigen
FZE25_RS16970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FZE25_RS16975	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS16975	COG0297	glycogen (starch) synthase activity
FZE25_RS16980	COG2244	polysaccharide biosynthetic process
FZE25_RS16990	COG2247	cell wall binding repeat
FZE25_RS16990	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZE25_RS16995	COG2385	sporulation resulting in formation of a cellular spore
FZE25_RS16995	COG2247	cell wall binding repeat
FZE25_RS17005	COG1316	TRANSCRIPTIONal
FZE25_RS17015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FZE25_RS17020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FZE25_RS17025	COG1134	teichoic acid transport
FZE25_RS17030	COG1682	transport, permease protein
FZE25_RS17035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FZE25_RS17045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FZE25_RS17050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FZE25_RS17055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FZE25_RS17060	COG4193	domain, Protein
FZE25_RS17065	COG1482	cell wall glycoprotein biosynthetic process
FZE25_RS17070	COG0697	spore germination
FZE25_RS17075	COG0814	amino acid
FZE25_RS17085	COG1215	transferase activity, transferring glycosyl groups
FZE25_RS17090	COG2814	Major facilitator Superfamily
FZE25_RS17095	COG1316	TRANSCRIPTIONal
FZE25_RS17100	COG0561	phosphatase activity
FZE25_RS17105	COG2433	Pfam Transposase IS66
FZE25_RS17110	COG0791	NLP P60 protein
FZE25_RS17120	COG2843	Capsule synthesis protein
FZE25_RS17130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FZE25_RS17140	COG0697	spore germination
FZE25_RS17145	COG0814	amino acid
FZE25_RS17155	COG1609	Transcriptional regulator
FZE25_RS17160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FZE25_RS17170	COG1129	ABC transporter
FZE25_RS17175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FZE25_RS17180	COG1879	ABC-type sugar transport system periplasmic component
FZE25_RS17185	COG3103	Sh3 type 3 domain protein
FZE25_RS17190	COG2249	NAD(P)H dehydrogenase (quinone) activity
FZE25_RS17195	COG3527	Alpha-acetolactate decarboxylase
FZE25_RS17200	COG0028	Belongs to the TPP enzyme family
FZE25_RS17205	COG0583	DNA-binding transcription factor activity
FZE25_RS17210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FZE25_RS17225	COG5337	Spore coat protein CotH
FZE25_RS17235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FZE25_RS17245	COG0405	Gamma-glutamyltransferase
FZE25_RS17250	COG1522	sequence-specific DNA binding
FZE25_RS17255	COG2059	Chromate
FZE25_RS17260	COG2059	Chromate
FZE25_RS17270	COG2849	repeat protein
FZE25_RS17275	COG5444	nuclease activity
FZE25_RS17290	COG3878	Protein conserved in bacteria
FZE25_RS17295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FZE25_RS17300	COG4464	protein tyrosine phosphatase activity
FZE25_RS17305	COG0489	protein tyrosine kinase activity
FZE25_RS17310	COG3944	biosynthesis protein
FZE25_RS17325	COG4715	Zinc finger, swim domain protein
FZE25_RS17330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FZE25_RS17335	COG0561	phosphatase activity
FZE25_RS17340	COG1349	DNA-binding transcription factor activity
FZE25_RS17345	COG0629	single-stranded DNA binding
FZE25_RS17370	COG0457	Tetratricopeptide repeat
FZE25_RS17375	COG4786	Flagellar basal body rod
FZE25_RS17380	COG4786	Flagellar basal body rod
FZE25_RS17385	COG1077	Cell shape determining protein MreB Mrl
FZE25_RS17390	COG1609	Transcriptional regulator
FZE25_RS17395	COG1846	Transcriptional regulator
FZE25_RS17400	COG2814	Major facilitator Superfamily
FZE25_RS17405	COG1953	Uracil, thiamine, allantoin
FZE25_RS17410	COG0477	Major facilitator Superfamily
FZE25_RS17415	COG1335	isochorismatase
FZE25_RS17420	COG0004	ammonium transporteR
FZE25_RS17425	COG0347	Belongs to the P(II) protein family
FZE25_RS17430	COG0772	Belongs to the SEDS family
FZE25_RS17435	COG0671	phosphoesterase, PA-phosphatase related
FZE25_RS17445	COG0739	heme binding
FZE25_RS17450	COG1247	-acetyltransferase
FZE25_RS17465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FZE25_RS17480	COG0726	polysaccharide deacetylase
FZE25_RS17485	COG1959	2 iron, 2 sulfur cluster binding
FZE25_RS17500	COG0831	urea catabolic process
FZE25_RS17505	COG3237	CsbD-like
FZE25_RS17510	COG1994	Peptidase M50
FZE25_RS17515	COG0457	Tetratricopeptide repeat
FZE25_RS17525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FZE25_RS17530	COG2304	oxidoreductase activity
FZE25_RS17535	COG2304	oxidoreductase activity
FZE25_RS17545	COG2385	sporulation resulting in formation of a cellular spore
FZE25_RS17550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FZE25_RS17560	COG4836	Membrane
FZE25_RS17630	COG0698	ribose 5-phosphate isomerase
FZE25_RS17635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FZE25_RS17645	COG0009	L-threonylcarbamoyladenylate synthase
FZE25_RS17650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FZE25_RS17670	COG2890	protein-(glutamine-N5) methyltransferase activity
FZE25_RS17675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FZE25_RS17680	COG0346	lactoylglutathione lyase activity
FZE25_RS17685	COG0789	Transcriptional regulator
FZE25_RS17690	COG0679	Auxin Efflux Carrier
FZE25_RS17695	COG0281	malic enzyme
FZE25_RS17710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FZE25_RS17715	COG1494	fructose-1,6-bisphosphatase
FZE25_RS17720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FZE25_RS17730	COG0191	fructose-bisphosphate aldolase activity
FZE25_RS17735	COG2204	response regulator
FZE25_RS17740	COG4821	SIS domain
FZE25_RS17755	COG2181	nitrate reductase activity
FZE25_RS17755	COG0247	lactate metabolic process
FZE25_RS17760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FZE25_RS17775	COG1132	(ABC) transporter
FZE25_RS17780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FZE25_RS17790	COG2181	nitrate reductase activity
FZE25_RS17795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FZE25_RS17800	COG1140	nitrate reductase beta subunit
FZE25_RS17805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FZE25_RS17810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FZE25_RS17820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FZE25_RS17825	COG2223	nitrite transmembrane transporter activity
FZE25_RS17835	COG4506	Protein conserved in bacteria
FZE25_RS17845	COG3391	amine dehydrogenase activity
FZE25_RS17850	COG3391	amine dehydrogenase activity
FZE25_RS17860	COG0457	Tetratricopeptide repeat
FZE25_RS17905	COG0010	Belongs to the arginase family
FZE25_RS17910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FZE25_RS17915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZE25_RS17930	COG1994	Peptidase M50
FZE25_RS17935	COG1942	4-Oxalocrotonate Tautomerase
FZE25_RS17940	COG1846	Transcriptional regulator
FZE25_RS17950	COG0531	amino acid
FZE25_RS17955	COG3465	dGTPase activity
FZE25_RS17960	COG1078	dGTPase activity
FZE25_RS17975	COG1695	Transcriptional regulator
FZE25_RS17985	COG1131	(ABC) transporter
FZE25_RS17990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FZE25_RS18020	COG0583	DNA-binding transcription factor activity
FZE25_RS18025	COG2855	membrane
FZE25_RS18030	COG0280	phosphate acetyltransferase
FZE25_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS18045	COG0436	Aminotransferase
FZE25_RS18075	COG2814	Major facilitator Superfamily
FZE25_RS18080	COG2814	Major facilitator Superfamily
FZE25_RS18085	COG0833	amino acid
FZE25_RS18090	COG4187	Peptidase family M20/M25/M40
FZE25_RS18095	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS18100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FZE25_RS18110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FZE25_RS18115	COG1091	dTDP-4-dehydrorhamnose reductase activity
FZE25_RS18120	COG1088	dTDP-glucose 4,6-dehydratase activity
FZE25_RS18125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FZE25_RS18130	COG3980	spore coat polysaccharide biosynthesis protein
FZE25_RS18135	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FZE25_RS18140	COG2089	acid synthase
FZE25_RS18145	COG0456	acetyltransferase
FZE25_RS18150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FZE25_RS18155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FZE25_RS18160	COG0463	Glycosyl transferase, family 2
FZE25_RS18170	COG2363	Small membrane protein
FZE25_RS18175	COG2233	PERMEase
FZE25_RS18190	COG1216	Glycosyl transferase, family 2
FZE25_RS18205	COG1695	Transcriptional regulator
FZE25_RS18210	COG0351	phosphomethylpyrimidine kinase
FZE25_RS18220	COG1621	beta-fructofuranosidase activity
FZE25_RS18225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS18225	COG1263	PTS System
FZE25_RS18230	COG3711	transcriptional antiterminator
FZE25_RS18240	COG1404	Belongs to the peptidase S8 family
FZE25_RS18245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZE25_RS18250	COG0778	Nitroreductase
FZE25_RS18255	COG0772	Belongs to the SEDS family
FZE25_RS18260	COG0454	-acetyltransferase
FZE25_RS18280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FZE25_RS18285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FZE25_RS18290	COG2261	transglycosylase associated protein
FZE25_RS18295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FZE25_RS18300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FZE25_RS18305	COG2246	polysaccharide biosynthetic process
FZE25_RS18310	COG1309	transcriptional regulator
FZE25_RS18330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FZE25_RS18335	COG2837	iron assimilation
FZE25_RS18340	COG2822	iron ion transport
FZE25_RS18355	COG0583	DNA-binding transcription factor activity
FZE25_RS18365	COG1346	cytolysis
FZE25_RS18370	COG4895	conserved protein (DUF2196)
FZE25_RS18375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FZE25_RS18380	COG0346	lactoylglutathione lyase activity
FZE25_RS18385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS18390	COG1404	Belongs to the peptidase S8 family
FZE25_RS18395	COG1442	glycosyl transferase family 8
FZE25_RS18400	COG2357	RelA SpoT domain protein
FZE25_RS18405	COG1575	Belongs to the MenA family. Type 1 subfamily
FZE25_RS18430	COG1696	Membrane protein involved in D-alanine export
FZE25_RS18440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FZE25_RS18445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FZE25_RS18450	COG1486	melibiose metabolic process
FZE25_RS18455	COG1447	Phosphotransferase system cellobiose-specific component IIA
FZE25_RS18460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS18465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS18470	COG3711	transcriptional antiterminator
FZE25_RS18470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZE25_RS18485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS18490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FZE25_RS18500	COG0640	Transcriptional regulator
FZE25_RS18505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FZE25_RS18510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS18515	COG1447	Phosphotransferase system cellobiose-specific component IIA
FZE25_RS18520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FZE25_RS18525	COG2723	6-phospho-beta-galactosidase activity
FZE25_RS18530	COG1940	carbohydrate kinase activity
FZE25_RS18535	COG1482	cell wall glycoprotein biosynthetic process
FZE25_RS18545	COG0753	catalase activity
FZE25_RS18550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FZE25_RS18555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FZE25_RS18560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FZE25_RS18565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FZE25_RS18570	COG4988	ABC transporter
FZE25_RS18575	COG1294	oxidase, subunit
FZE25_RS18580	COG1271	oxidase subunit
FZE25_RS18585	COG3493	citrate carrier protein
FZE25_RS18590	COG0726	polysaccharide deacetylase
FZE25_RS18595	COG3842	ATPase activity
FZE25_RS18600	COG2508	Transcriptional regulator
FZE25_RS18610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS18620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FZE25_RS18630	COG4894	glucomannan catabolic process
FZE25_RS18635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FZE25_RS18640	COG0500	methyltransferase
FZE25_RS18645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FZE25_RS18660	COG0693	protein deglycase activity
FZE25_RS18660	COG0753	catalase activity
FZE25_RS18665	COG2851	Citrate transporter
FZE25_RS18670	COG2273	Hydrolase Family 16
FZE25_RS18675	COG3711	transcriptional antiterminator
FZE25_RS18680	COG2270	Major facilitator Superfamily
FZE25_RS18685	COG0513	Belongs to the DEAD box helicase family
FZE25_RS18725	COG3209	COG3209 Rhs family protein
FZE25_RS18735	COG0697	spore germination
FZE25_RS18740	COG0589	response to stress
FZE25_RS18745	COG2723	6-phospho-beta-galactosidase activity
FZE25_RS18750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FZE25_RS18750	COG2190	(PTS) system
FZE25_RS18750	COG1263	PTS System
FZE25_RS18765	COG0494	nUDIX hydrolase
FZE25_RS18770	COG3507	Belongs to the glycosyl hydrolase 43 family
FZE25_RS18795	COG0010	Belongs to the arginase family
FZE25_RS18800	COG0833	amino acid
FZE25_RS18805	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FZE25_RS18810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FZE25_RS18820	COG2390	Transcriptional regulator
FZE25_RS18825	COG0561	phosphatase activity
FZE25_RS18855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FZE25_RS18860	COG5294	Protein conserved in bacteria
FZE25_RS18865	COG0577	efflux transmembrane transporter activity
FZE25_RS18870	COG1136	(ABC) transporter
FZE25_RS18875	COG2205	protein histidine kinase activity
FZE25_RS18880	COG0745	RESPONSE REGULATOR receiver
FZE25_RS18895	COG1082	Xylose isomerase domain protein TIM barrel
FZE25_RS18905	COG2814	Major facilitator Superfamily
FZE25_RS18935	COG1349	DNA-binding transcription factor activity
FZE25_RS18940	COG0667	Aldo Keto reductase
FZE25_RS18945	COG2814	Major facilitator Superfamily
FZE25_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS18965	COG2197	response regulator
FZE25_RS18970	COG4585	Histidine kinase
FZE25_RS18975	COG3239	Fatty acid desaturase
FZE25_RS18985	COG1309	transcriptional regulator
FZE25_RS18990	COG1012	belongs to the aldehyde dehydrogenase family
FZE25_RS18995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FZE25_RS19005	COG0640	Transcriptional regulator
FZE25_RS19010	COG2814	Major facilitator Superfamily
FZE25_RS19015	COG1714	RDD family
FZE25_RS19025	COG0450	alkyl hydroperoxide reductase
FZE25_RS19030	COG3634	alkyl hydroperoxide reductase activity
FZE25_RS19035	COG3177	Filamentation induced by cAMP protein fic
FZE25_RS19040	COG1113	amino acid transport
FZE25_RS19050	COG2080	2 iron, 2 sulfur cluster binding
FZE25_RS19065	COG2068	MobA-Related Protein
FZE25_RS19070	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FZE25_RS19085	COG1715	Restriction endonuclease
FZE25_RS19120	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FZE25_RS19125	COG0667	Aldo Keto reductase
FZE25_RS19130	COG0456	acetyltransferase
FZE25_RS19135	COG0457	Tetratricopeptide repeat
FZE25_RS19140	COG0010	Belongs to the arginase family
FZE25_RS19145	COG0833	amino acid
FZE25_RS19150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FZE25_RS19155	COG5658	integral membrane protein
FZE25_RS19160	COG0640	Transcriptional regulator
FZE25_RS19165	COG3829	transcription factor binding
FZE25_RS19175	COG0488	(ABC) transporter
FZE25_RS19190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FZE25_RS19195	COG5002	protein histidine kinase activity
FZE25_RS19195	COG3850	Histidine kinase
FZE25_RS19200	COG0745	RESPONSE REGULATOR receiver
FZE25_RS19205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZE25_RS19210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FZE25_RS19215	COG4853	Protein conserved in bacteria
FZE25_RS19220	COG4863	YycH protein
FZE25_RS19225	COG5002	protein histidine kinase activity
FZE25_RS19230	COG0745	RESPONSE REGULATOR receiver
FZE25_RS19265	COG0346	lactoylglutathione lyase activity
FZE25_RS19270	COG0305	Participates in initiation and elongation during chromosome replication
FZE25_RS19290	COG3093	addiction module antidote protein HigA
FZE25_RS19295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FZE25_RS19310	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FZE25_RS19315	COG0438	transferase activity, transferring glycosyl groups
FZE25_RS19335	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FZE25_RS19340	COG4241	membrane
FZE25_RS19350	COG5577	PFAM Coat F domain
FZE25_RS19355	COG1733	regulation of RNA biosynthetic process
FZE25_RS19365	COG0697	spore germination
FZE25_RS19370	COG1621	beta-fructofuranosidase activity
FZE25_RS19375	COG1621	beta-fructofuranosidase activity
FZE25_RS19380	COG1802	Transcriptional regulator
FZE25_RS19385	COG2318	DinB family
FZE25_RS19390	COG2211	Major facilitator Superfamily
FZE25_RS19395	COG0583	DNA-binding transcription factor activity
FZE25_RS19410	COG0778	Nitroreductase
FZE25_RS19415	COG1846	Transcriptional regulator
FZE25_RS19420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FZE25_RS19425	COG1846	Transcriptional regulator
FZE25_RS19430	COG2153	protein acetylation
FZE25_RS19440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FZE25_RS19445	COG0583	DNA-binding transcription factor activity
FZE25_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
FZE25_RS19455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZE25_RS19460	COG0697	spore germination
FZE25_RS19465	COG1331	Highly conserved protein containing a thioredoxin domain
FZE25_RS19475	COG1078	dGTPase activity
FZE25_RS19490	COG1331	Highly conserved protein containing a thioredoxin domain
FZE25_RS19495	COG1266	CAAX protease self-immunity
FZE25_RS19500	COG2814	Major facilitator Superfamily
FZE25_RS19500	COG0477	Major facilitator Superfamily
FZE25_RS19505	COG0346	lactoylglutathione lyase activity
FZE25_RS19510	COG1609	Transcriptional regulator
FZE25_RS19515	COG0708	Exodeoxyribonuclease III
FZE25_RS19520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FZE25_RS19525	COG2169	Transcriptional regulator
FZE25_RS19535	COG0629	single-stranded DNA binding
FZE25_RS19545	COG0012	GTP binding
FZE25_RS19550	COG0243	molybdopterin cofactor binding
FZE25_RS19555	COG4481	Protein conserved in bacteria
FZE25_RS19560	COG3949	Membrane
FZE25_RS19575	COG1475	DNA binding
FZE25_RS19580	COG1192	Involved in chromosome partitioning
FZE25_RS19605	COG1847	R3H domain protein
FZE25_RS19610	COG0706	membrane insertase activity