locus-tag	class	description
HT132_RS00110	COG0726	polysaccharide deacetylase
HT132_RS00115	COG2194	sulfuric ester hydrolase activity
HT132_RS00125	COG0489	protein tyrosine kinase activity
HT132_RS00130	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS00140	COG2318	DinB family
HT132_RS00145	COG2226	methyltransferase
HT132_RS00165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HT132_RS00170	COG1122	ATPase activity
HT132_RS00175	COG1122	ATPase activity
HT132_RS00200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HT132_RS00210	COG0024	Methionine aminopeptidase
HT132_RS00220	COG0201	protein transport
HT132_RS00330	COG0596	Alpha beta hydrolase
HT132_RS00355	COG1358	cellular component organization or biogenesis
HT132_RS00370	COG2813	Specifically methylates the guanine in position
HT132_RS00395	COG0250	Participates in transcription elongation, termination and antitermination
HT132_RS00400	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HT132_RS00410	COG1595	DNA-templated transcription, initiation
HT132_RS00415	COG3688	RNA-binding protein containing a PIN domain
HT132_RS00420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HT132_RS00425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HT132_RS00435	COG1045	serine acetyltransferase
HT132_RS00455	COG4956	integral membrane protein (PIN domain superfamily)
HT132_RS00460	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HT132_RS00465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HT132_RS00470	COG0542	response to heat
HT132_RS00480	COG3880	PFAM UvrB UvrC protein
HT132_RS00485	COG4463	regulation of RNA biosynthetic process
HT132_RS00565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HT132_RS00570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HT132_RS00575	COG1396	sequence-specific DNA binding
HT132_RS00580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HT132_RS00585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HT132_RS00590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HT132_RS00595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_RS00600	COG0512	Glutamine amidotransferase of anthranilate synthase
HT132_RS00605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HT132_RS00610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_RS00615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HT132_RS00630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HT132_RS00640	COG0037	tRNA processing
HT132_RS00645	COG0515	serine threonine protein kinase
HT132_RS00650	COG2304	oxidoreductase activity
HT132_RS00655	COG2208	phosphoserine phosphatase activity
HT132_RS00670	COG1098	S1 RNA binding domain
HT132_RS00675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HT132_RS00690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HT132_RS00695	COG3956	TIGRFAM MazG family protein
HT132_RS00700	COG2244	polysaccharide biosynthetic process
HT132_RS00705	COG2002	toxin-antitoxin pair type II binding
HT132_RS00710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HT132_RS00730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HT132_RS00745	COG0251	oxidation-reduction process
HT132_RS00750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HT132_RS00765	COG4466	Protein conserved in bacteria
HT132_RS00775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HT132_RS00780	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HT132_RS00785	COG3584	3D domain protein
HT132_RS00785	COG3583	domain protein
HT132_RS00790	COG0084	hydrolase, TatD family'
HT132_RS00795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_RS00795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_RS00800	COG2002	toxin-antitoxin pair type II binding
HT132_RS00805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HT132_RS00815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HT132_RS00825	COG1774	PSP1 C-terminal conserved region
HT132_RS00830	COG0470	DNA polymerase III
HT132_RS00835	COG1728	Protein conserved in bacteria
HT132_RS00840	COG3870	Protein conserved in bacteria
HT132_RS00850	COG1982	Orn Lys Arg decarboxylase major
HT132_RS00855	COG3853	Toxic anion resistance protein (TelA)
HT132_RS00860	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HT132_RS00910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HT132_RS00915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HT132_RS00925	COG0590	tRNA wobble adenosine to inosine editing
HT132_RS00930	COG1335	isochorismatase
HT132_RS00935	COG3858	chitin binding
HT132_RS00935	COG1388	LysM domain
HT132_RS00940	COG1428	Deoxynucleoside kinase
HT132_RS00945	COG1428	Deoxynucleoside kinase
HT132_RS00955	COG1929	Belongs to the glycerate kinase type-1 family
HT132_RS00975	COG1686	Belongs to the peptidase S11 family
HT132_RS00980	COG0517	IMP dehydrogenase activity
HT132_RS00980	COG0516	GMP reductase activity
HT132_RS01015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HT132_RS01020	COG0187	DNA topoisomerase II activity
HT132_RS01035	COG2501	S4 domain
HT132_RS01040	COG0592	DNA-directed DNA polymerase activity
HT132_RS01060	COG0706	membrane insertase activity
HT132_RS01065	COG1847	R3H domain protein
HT132_RS01090	COG1192	Involved in chromosome partitioning
HT132_RS01095	COG1475	DNA binding
HT132_RS01110	COG3949	Membrane
HT132_RS01115	COG4481	Protein conserved in bacteria
HT132_RS01120	COG0243	molybdopterin cofactor binding
HT132_RS01125	COG0012	GTP binding
HT132_RS01135	COG0629	single-stranded DNA binding
HT132_RS01145	COG2169	Transcriptional regulator
HT132_RS01150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HT132_RS01160	COG1609	Transcriptional regulator
HT132_RS01165	COG0346	lactoylglutathione lyase activity
HT132_RS01170	COG2814	Major facilitator Superfamily
HT132_RS01170	COG0477	Major facilitator Superfamily
HT132_RS01175	COG1266	CAAX protease self-immunity
HT132_RS01180	COG1331	Highly conserved protein containing a thioredoxin domain
HT132_RS01185	COG0697	spore germination
HT132_RS01190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS01195	COG0492	ferredoxin-NADP+ reductase activity
HT132_RS01205	COG0546	phosphoglycolate phosphatase activity
HT132_RS01215	COG2153	protein acetylation
HT132_RS01220	COG1846	Transcriptional regulator
HT132_RS01225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS01230	COG1846	Transcriptional regulator
HT132_RS01235	COG0778	Nitroreductase
HT132_RS01245	COG0697	spore germination
HT132_RS01250	COG2211	Major facilitator Superfamily
HT132_RS01255	COG2318	DinB family
HT132_RS01260	COG1802	Transcriptional regulator
HT132_RS01265	COG1621	beta-fructofuranosidase activity
HT132_RS01270	COG1621	beta-fructofuranosidase activity
HT132_RS01275	COG0697	spore germination
HT132_RS01285	COG1733	regulation of RNA biosynthetic process
HT132_RS01290	COG5577	PFAM Coat F domain
HT132_RS01300	COG4241	membrane
HT132_RS01305	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HT132_RS01315	COG2112	serine threonine protein kinase
HT132_RS01325	COG0438	transferase activity, transferring glycosyl groups
HT132_RS01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HT132_RS01340	COG0297	glycogen (starch) synthase activity
HT132_RS01345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HT132_RS01350	COG3093	addiction module antidote protein HigA
HT132_RS01365	COG0305	Participates in initiation and elongation during chromosome replication
HT132_RS01370	COG0346	lactoylglutathione lyase activity
HT132_RS01400	COG0745	RESPONSE REGULATOR receiver
HT132_RS01405	COG5002	protein histidine kinase activity
HT132_RS01410	COG4863	YycH protein
HT132_RS01415	COG4853	Protein conserved in bacteria
HT132_RS01420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HT132_RS01425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_RS01435	COG0745	RESPONSE REGULATOR receiver
HT132_RS01440	COG3850	Histidine kinase
HT132_RS01440	COG5002	protein histidine kinase activity
HT132_RS01445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_RS01460	COG0488	(ABC) transporter
HT132_RS01470	COG3829	transcription factor binding
HT132_RS01475	COG0640	Transcriptional regulator
HT132_RS01480	COG5658	integral membrane protein
HT132_RS01485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HT132_RS01490	COG0833	amino acid
HT132_RS01495	COG0010	Belongs to the arginase family
HT132_RS01500	COG0457	Tetratricopeptide repeat
HT132_RS01505	COG0456	acetyltransferase
HT132_RS01515	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HT132_RS01560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HT132_RS01565	COG2068	MobA-Related Protein
HT132_RS01580	COG2080	2 iron, 2 sulfur cluster binding
HT132_RS01590	COG1113	amino acid transport
HT132_RS01595	COG3177	Filamentation induced by cAMP protein fic
HT132_RS01600	COG3634	alkyl hydroperoxide reductase activity
HT132_RS01605	COG0450	alkyl hydroperoxide reductase
HT132_RS01610	COG1715	Restriction endonuclease
HT132_RS01615	COG0501	Belongs to the peptidase M48B family
HT132_RS01625	COG1714	RDD family
HT132_RS01630	COG2814	Major facilitator Superfamily
HT132_RS01635	COG0640	Transcriptional regulator
HT132_RS01645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HT132_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS01655	COG1309	transcriptional regulator
HT132_RS01660	COG3239	Fatty acid desaturase
HT132_RS01665	COG4585	Histidine kinase
HT132_RS01670	COG2197	response regulator
HT132_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS01685	COG2814	Major facilitator Superfamily
HT132_RS01690	COG0667	Aldo Keto reductase
HT132_RS01695	COG1349	DNA-binding transcription factor activity
HT132_RS01725	COG2814	Major facilitator Superfamily
HT132_RS01735	COG1082	Xylose isomerase domain protein TIM barrel
HT132_RS01765	COG0745	RESPONSE REGULATOR receiver
HT132_RS01770	COG2205	protein histidine kinase activity
HT132_RS01775	COG0745	RESPONSE REGULATOR receiver
HT132_RS01780	COG2205	protein histidine kinase activity
HT132_RS01785	COG1136	(ABC) transporter
HT132_RS01790	COG0577	efflux transmembrane transporter activity
HT132_RS01795	COG5294	Protein conserved in bacteria
HT132_RS01800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_RS01830	COG0561	phosphatase activity
HT132_RS01835	COG2390	Transcriptional regulator
HT132_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_RS01850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HT132_RS01855	COG0833	amino acid
HT132_RS01860	COG0010	Belongs to the arginase family
HT132_RS01885	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_RS01890	COG0494	nUDIX hydrolase
HT132_RS01900	COG0589	response to stress
HT132_RS01905	COG0697	spore germination
HT132_RS01960	COG0513	Belongs to the DEAD box helicase family
HT132_RS01965	COG2270	Major facilitator Superfamily
HT132_RS01970	COG3711	transcriptional antiterminator
HT132_RS01975	COG2273	Hydrolase Family 16
HT132_RS01980	COG2851	Citrate transporter
HT132_RS01985	COG0753	catalase activity
HT132_RS01985	COG0693	protein deglycase activity
HT132_RS02005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_RS02010	COG0500	methyltransferase
HT132_RS02015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HT132_RS02020	COG4894	glucomannan catabolic process
HT132_RS02035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HT132_RS02045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS02050	COG2508	Transcriptional regulator
HT132_RS02055	COG3842	ATPase activity
HT132_RS02060	COG0726	polysaccharide deacetylase
HT132_RS02065	COG3493	citrate carrier protein
HT132_RS02070	COG1271	oxidase subunit
HT132_RS02075	COG1294	oxidase, subunit
HT132_RS02080	COG4988	ABC transporter
HT132_RS02085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HT132_RS02090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HT132_RS02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HT132_RS02100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HT132_RS02105	COG0753	catalase activity
HT132_RS02115	COG1482	cell wall glycoprotein biosynthetic process
HT132_RS02120	COG1940	carbohydrate kinase activity
HT132_RS02125	COG2723	6-phospho-beta-galactosidase activity
HT132_RS02130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS02135	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_RS02140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS02145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HT132_RS02150	COG0640	Transcriptional regulator
HT132_RS02160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS02165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS02175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS02175	COG3711	transcriptional antiterminator
HT132_RS02180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS02185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS02190	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_RS02195	COG1486	melibiose metabolic process
HT132_RS02200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_RS02205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HT132_RS02215	COG1696	Membrane protein involved in D-alanine export
HT132_RS02230	COG1575	Belongs to the MenA family. Type 1 subfamily
HT132_RS02235	COG2357	RelA SpoT domain protein
HT132_RS02240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HT132_RS02250	COG1442	glycosyl transferase family 8
HT132_RS02255	COG1404	Belongs to the peptidase S8 family
HT132_RS02260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS02265	COG0346	lactoylglutathione lyase activity
HT132_RS02270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HT132_RS02275	COG5504	Zn-dependent protease
HT132_RS02280	COG0789	Transcriptional regulator
HT132_RS02285	COG4895	conserved protein (DUF2196)
HT132_RS02290	COG1346	cytolysis
HT132_RS02300	COG0583	DNA-binding transcription factor activity
HT132_RS02315	COG2822	iron ion transport
HT132_RS02320	COG2837	iron assimilation
HT132_RS02325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HT132_RS02345	COG1309	transcriptional regulator
HT132_RS02350	COG2246	polysaccharide biosynthetic process
HT132_RS02355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HT132_RS02360	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HT132_RS02365	COG2261	transglycosylase associated protein
HT132_RS02370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HT132_RS02375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HT132_RS02395	COG0454	-acetyltransferase
HT132_RS02400	COG0772	Belongs to the SEDS family
HT132_RS02405	COG0778	Nitroreductase
HT132_RS02410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS02425	COG3711	transcriptional antiterminator
HT132_RS02430	COG1263	PTS System
HT132_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS02435	COG1621	beta-fructofuranosidase activity
HT132_RS02445	COG0351	phosphomethylpyrimidine kinase
HT132_RS02450	COG1695	Transcriptional regulator
HT132_RS02465	COG1216	Glycosyl transferase, family 2
HT132_RS02480	COG2233	PERMEase
HT132_RS02485	COG2363	Small membrane protein
HT132_RS02495	COG0463	Glycosyl transferase, family 2
HT132_RS02500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_RS02505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HT132_RS02510	COG0456	acetyltransferase
HT132_RS02515	COG2089	acid synthase
HT132_RS02520	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HT132_RS02525	COG3980	spore coat polysaccharide biosynthesis protein
HT132_RS02530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HT132_RS02535	COG1088	dTDP-glucose 4,6-dehydratase activity
HT132_RS02540	COG1091	dTDP-4-dehydrorhamnose reductase activity
HT132_RS02545	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HT132_RS02550	COG1131	(ABC) transporter
HT132_RS02565	COG0745	RESPONSE REGULATOR receiver
HT132_RS02570	COG2205	protein histidine kinase activity
HT132_RS02575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_RS02580	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS02585	COG4187	Peptidase family M20/M25/M40
HT132_RS02590	COG0833	amino acid
HT132_RS02595	COG2814	Major facilitator Superfamily
HT132_RS02600	COG2814	Major facilitator Superfamily
HT132_RS02630	COG0436	Aminotransferase
HT132_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS02645	COG0280	phosphate acetyltransferase
HT132_RS02650	COG2855	membrane
HT132_RS02655	COG0583	DNA-binding transcription factor activity
HT132_RS02685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_RS02690	COG1131	(ABC) transporter
HT132_RS02700	COG1695	Transcriptional regulator
HT132_RS02715	COG1078	dGTPase activity
HT132_RS02720	COG3465	dGTPase activity
HT132_RS02725	COG0531	amino acid
HT132_RS02735	COG1846	Transcriptional regulator
HT132_RS02740	COG1942	4-Oxalocrotonate Tautomerase
HT132_RS02745	COG1994	Peptidase M50
HT132_RS02760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_RS02765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HT132_RS02770	COG0010	Belongs to the arginase family
HT132_RS02810	COG0457	Tetratricopeptide repeat
HT132_RS02815	COG4506	Protein conserved in bacteria
HT132_RS02825	COG2223	nitrite transmembrane transporter activity
HT132_RS02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_RS02840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_RS02845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HT132_RS02850	COG1140	nitrate reductase beta subunit
HT132_RS02855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HT132_RS02860	COG2181	nitrate reductase activity
HT132_RS02870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_RS02875	COG1132	(ABC) transporter
HT132_RS02890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_RS02895	COG2181	nitrate reductase activity
HT132_RS02895	COG0247	lactate metabolic process
HT132_RS02910	COG4821	SIS domain
HT132_RS02915	COG2204	response regulator
HT132_RS02920	COG0191	fructose-bisphosphate aldolase activity
HT132_RS02930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HT132_RS02935	COG1494	fructose-1,6-bisphosphatase
HT132_RS02940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HT132_RS02955	COG0281	malic enzyme
HT132_RS02960	COG0679	Auxin Efflux Carrier
HT132_RS02965	COG0789	Transcriptional regulator
HT132_RS02970	COG0346	lactoylglutathione lyase activity
HT132_RS02975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HT132_RS02980	COG2890	protein-(glutamine-N5) methyltransferase activity
HT132_RS03000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HT132_RS03005	COG0009	L-threonylcarbamoyladenylate synthase
HT132_RS03015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HT132_RS03020	COG0698	ribose 5-phosphate isomerase
HT132_RS03090	COG4836	Membrane
HT132_RS03100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HT132_RS03105	COG2385	sporulation resulting in formation of a cellular spore
HT132_RS03110	COG2304	oxidoreductase activity
HT132_RS03115	COG2304	oxidoreductase activity
HT132_RS03125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HT132_RS03135	COG0457	Tetratricopeptide repeat
HT132_RS03140	COG1994	Peptidase M50
HT132_RS03150	COG0831	urea catabolic process
HT132_RS03165	COG1959	2 iron, 2 sulfur cluster binding
HT132_RS03170	COG0726	polysaccharide deacetylase
HT132_RS03180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HT132_RS03195	COG1247	-acetyltransferase
HT132_RS03200	COG0739	heme binding
HT132_RS03210	COG0671	phosphoesterase, PA-phosphatase related
HT132_RS03215	COG0772	Belongs to the SEDS family
HT132_RS03220	COG0347	Belongs to the P(II) protein family
HT132_RS03225	COG0004	ammonium transporteR
HT132_RS03230	COG1335	isochorismatase
HT132_RS03235	COG0477	Major facilitator Superfamily
HT132_RS03240	COG1953	Uracil, thiamine, allantoin
HT132_RS03245	COG2814	Major facilitator Superfamily
HT132_RS03250	COG1846	Transcriptional regulator
HT132_RS03255	COG1609	Transcriptional regulator
HT132_RS03260	COG1077	Cell shape determining protein MreB Mrl
HT132_RS03265	COG4786	Flagellar basal body rod
HT132_RS03270	COG4786	Flagellar basal body rod
HT132_RS03275	COG0457	Tetratricopeptide repeat
HT132_RS03300	COG0629	single-stranded DNA binding
HT132_RS03305	COG1349	DNA-binding transcription factor activity
HT132_RS03310	COG0561	phosphatase activity
HT132_RS03315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HT132_RS03320	COG4715	Zinc finger, swim domain protein
HT132_RS03330	COG3944	biosynthesis protein
HT132_RS03335	COG0489	protein tyrosine kinase activity
HT132_RS03340	COG4464	protein tyrosine phosphatase activity
HT132_RS03345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HT132_RS03350	COG3878	Protein conserved in bacteria
HT132_RS03365	COG5444	nuclease activity
HT132_RS03370	COG2849	repeat protein
HT132_RS03375	COG1515	deoxyribonuclease V activity
HT132_RS03380	COG0583	DNA-binding transcription factor activity
HT132_RS03385	COG0655	NAD(P)H dehydrogenase (quinone) activity
HT132_RS03395	COG2059	Chromate
HT132_RS03400	COG2059	Chromate
HT132_RS03405	COG1522	sequence-specific DNA binding
HT132_RS03410	COG0405	Gamma-glutamyltransferase
HT132_RS03420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HT132_RS03430	COG5337	Spore coat protein CotH
HT132_RS03445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HT132_RS03450	COG0583	DNA-binding transcription factor activity
HT132_RS03455	COG0028	Belongs to the TPP enzyme family
HT132_RS03460	COG3527	Alpha-acetolactate decarboxylase
HT132_RS03465	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_RS03470	COG3103	Sh3 type 3 domain protein
HT132_RS03475	COG1879	ABC-type sugar transport system periplasmic component
HT132_RS03480	COG1172	Belongs to the binding-protein-dependent transport system permease family
HT132_RS03485	COG1129	ABC transporter
HT132_RS03495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_RS03500	COG1609	Transcriptional regulator
HT132_RS03510	COG0814	amino acid
HT132_RS03515	COG0697	spore germination
HT132_RS03520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HT132_RS03530	COG2843	Capsule synthesis protein
HT132_RS03540	COG0791	NLP P60 protein
HT132_RS03545	COG2433	Pfam Transposase IS66
HT132_RS03550	COG0561	phosphatase activity
HT132_RS03555	COG1316	TRANSCRIPTIONal
HT132_RS03560	COG2814	Major facilitator Superfamily
HT132_RS03565	COG1215	transferase activity, transferring glycosyl groups
HT132_RS03575	COG0814	amino acid
HT132_RS03580	COG0697	spore germination
HT132_RS03585	COG1482	cell wall glycoprotein biosynthetic process
HT132_RS03590	COG4193	domain, Protein
HT132_RS03595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_RS03600	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HT132_RS03605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HT132_RS03615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HT132_RS03620	COG1682	transport, permease protein
HT132_RS03625	COG1134	teichoic acid transport
HT132_RS03630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HT132_RS03635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HT132_RS03640	COG1316	TRANSCRIPTIONal
HT132_RS03650	COG2385	sporulation resulting in formation of a cellular spore
HT132_RS03650	COG2247	cell wall binding repeat
HT132_RS03655	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS03655	COG2247	cell wall binding repeat
HT132_RS03665	COG2244	polysaccharide biosynthetic process
HT132_RS03670	COG0297	glycogen (starch) synthase activity
HT132_RS03670	COG0438	transferase activity, transferring glycosyl groups
HT132_RS03675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HT132_RS03680	COG3307	-O-antigen
HT132_RS03685	COG3206	protein involved in exopolysaccharide biosynthesis
HT132_RS03690	COG1215	transferase activity, transferring glycosyl groups
HT132_RS03695	COG0438	transferase activity, transferring glycosyl groups
HT132_RS03700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HT132_RS03705	COG1316	TRANSCRIPTIONal
HT132_RS03710	COG1739	Uncharacterized protein family UPF0029
HT132_RS03715	COG4585	Histidine kinase
HT132_RS03720	COG2197	response regulator
HT132_RS03725	COG1307	EDD domain protein, DegV family
HT132_RS03730	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HT132_RS03740	COG1040	competence protein
HT132_RS03750	COG2747	anti-sigma28 factor FlgM
HT132_RS03755	COG3418	PFAM FlgN family protein
HT132_RS03760	COG1256	bacterial-type flagellum assembly
HT132_RS03760	COG4786	Flagellar basal body rod
HT132_RS03765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HT132_RS03785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HT132_RS03790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HT132_RS03795	COG1516	flagellar protein fliS
HT132_RS03810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HT132_RS03825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS03830	COG2010	Cytochrome c
HT132_RS03835	COG2884	Cell division ATP-binding protein ftsE
HT132_RS03840	COG2177	Part of the ABC transporter FtsEX involved in
HT132_RS03845	COG3420	alginic acid biosynthetic process
HT132_RS03850	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS03850	COG0793	Belongs to the peptidase S41A family
HT132_RS03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS03905	COG2814	Major facilitator Superfamily
HT132_RS03910	COG1309	transcriptional regulator
HT132_RS03915	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_RS03915	COG3848	Pyruvate phosphate dikinase
HT132_RS03920	COG4897	Protein conserved in bacteria
HT132_RS03930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HT132_RS03945	COG3595	metallopeptidase activity
HT132_RS03950	COG1983	PspC domain protein
HT132_RS03955	COG1950	PFAM Membrane protein of
HT132_RS03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HT132_RS03965	COG1309	transcriptional regulator
HT132_RS03970	COG2188	Transcriptional regulator
HT132_RS03980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HT132_RS04000	COG0110	maltose O-acetyltransferase activity
HT132_RS04005	COG4990	cell redox homeostasis
HT132_RS04020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HT132_RS04045	COG0140	phosphoribosyl-ATP diphosphatase activity
HT132_RS04045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HT132_RS04050	COG1132	(ABC) transporter
HT132_RS04060	COG0745	RESPONSE REGULATOR receiver
HT132_RS04065	COG5002	protein histidine kinase activity
HT132_RS04070	COG0457	Tetratricopeptide repeat
HT132_RS04075	COG3883	PFAM NLP P60 protein
HT132_RS04075	COG0791	NLP P60 protein
HT132_RS04080	COG0492	ferredoxin-NADP+ reductase activity
HT132_RS04085	COG1051	belongs to the nudix hydrolase family
HT132_RS04095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HT132_RS04105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS04110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HT132_RS04115	COG4290	ribonuclease
HT132_RS04120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HT132_RS04125	COG0288	reversible hydration of carbon dioxide
HT132_RS04130	COG0659	secondary active sulfate transmembrane transporter activity
HT132_RS04135	COG1694	Mazg nucleotide pyrophosphohydrolase
HT132_RS04140	COG1611	Belongs to the LOG family
HT132_RS04145	COG1609	Transcriptional regulator
HT132_RS04150	COG0366	Alpha amylase catalytic
HT132_RS04155	COG2182	Extracellular solute-binding protein
HT132_RS04160	COG1175	transmembrane transport
HT132_RS04165	COG3833	ABC-type maltose transport systems, permease component
HT132_RS04170	COG5521	maltodextrose utilization protein MalA
HT132_RS04175	COG1554	hydrolase, family 65, central catalytic
HT132_RS04180	COG0366	Alpha amylase catalytic
HT132_RS04185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HT132_RS04195	COG1609	Transcriptional regulator
HT132_RS04200	COG2223	nitrite transmembrane transporter activity
HT132_RS04240	COG3479	Phenolic acid decarboxylase
HT132_RS04245	COG0456	acetyltransferase
HT132_RS04250	COG2364	Membrane
HT132_RS04255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HT132_RS04265	COG2272	Belongs to the type-B carboxylesterase lipase family
HT132_RS04270	COG1396	sequence-specific DNA binding
HT132_RS04275	COG3944	biosynthesis protein
HT132_RS04280	COG0489	protein tyrosine kinase activity
HT132_RS04285	COG1086	Polysaccharide biosynthesis protein
HT132_RS04290	COG0438	transferase activity, transferring glycosyl groups
HT132_RS04295	COG1215	transferase activity, transferring glycosyl groups
HT132_RS04300	COG0438	transferase activity, transferring glycosyl groups
HT132_RS04310	COG1216	Glycosyl transferase, family 2
HT132_RS04315	COG5039	Polysaccharide pyruvyl transferase
HT132_RS04320	COG1216	Glycosyl transferase, family 2
HT132_RS04325	COG2244	polysaccharide biosynthetic process
HT132_RS04330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HT132_RS04335	COG0110	maltose O-acetyltransferase activity
HT132_RS04340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HT132_RS04345	COG5039	Polysaccharide pyruvyl transferase
HT132_RS04355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HT132_RS04360	COG1620	l-lactate permease
HT132_RS04365	COG2186	Transcriptional regulator
HT132_RS04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS04400	COG1070	Carbohydrate kinase
HT132_RS04405	COG1737	Transcriptional regulator
HT132_RS04415	COG1113	amino acid transport
HT132_RS04420	COG0697	spore germination
HT132_RS04425	COG0583	DNA-binding transcription factor activity
HT132_RS04430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS04435	COG1609	Transcriptional regulator
HT132_RS04440	COG2814	Major facilitator Superfamily
HT132_RS04445	COG2390	Transcriptional regulator
HT132_RS04450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HT132_RS04455	COG0126	phosphoglycerate kinase activity
HT132_RS04475	COG0456	acetyltransferase
HT132_RS04480	COG4640	response to antibiotic
HT132_RS04485	COG3064	Membrane
HT132_RS04490	COG2095	MarC family integral membrane protein
HT132_RS04495	COG1510	regulation of RNA biosynthetic process
HT132_RS04500	COG0517	IMP dehydrogenase activity
HT132_RS04500	COG1125	glycine betaine transport
HT132_RS04505	COG1174	glycine betaine transport
HT132_RS04510	COG1732	Glycine betaine
HT132_RS04515	COG1174	glycine betaine transport
HT132_RS04520	COG1510	regulation of RNA biosynthetic process
HT132_RS04525	COG0517	IMP dehydrogenase activity
HT132_RS04525	COG1125	glycine betaine transport
HT132_RS04530	COG1174	glycine betaine transport
HT132_RS04535	COG1732	Glycine betaine
HT132_RS04540	COG1174	glycine betaine transport
HT132_RS04545	COG1131	(ABC) transporter
HT132_RS04570	COG1733	regulation of RNA biosynthetic process
HT132_RS04575	COG1396	sequence-specific DNA binding
HT132_RS04580	COG1396	sequence-specific DNA binding
HT132_RS04585	COG1476	TRANSCRIPTIONal
HT132_RS04590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HT132_RS04595	COG1647	Serine aminopeptidase, S33
HT132_RS04600	COG0557	exoribonuclease II activity
HT132_RS04615	COG2732	(Barnase) inhibitor
HT132_RS04620	COG2732	(Barnase) inhibitor
HT132_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS04630	COG0583	DNA-binding transcription factor activity
HT132_RS04635	COG0454	-acetyltransferase
HT132_RS04640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS04645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS04650	COG0765	amino acid transport
HT132_RS04655	COG0765	amino acid transport
HT132_RS04660	COG1126	abc transporter atp-binding protein
HT132_RS04665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS04670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HT132_RS04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS04685	COG0673	inositol 2-dehydrogenase activity
HT132_RS04690	COG1937	Protein conserved in bacteria
HT132_RS04695	COG2608	mercury ion transmembrane transporter activity
HT132_RS04700	COG2217	Heavy metal translocating P-type atpase
HT132_RS04705	COG2217	Heavy metal translocating P-type atpase
HT132_RS04710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HT132_RS04715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HT132_RS04725	COG2860	membrane
HT132_RS04730	COG3973	AAA domain
HT132_RS04735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_RS04755	COG0656	L-ascorbic acid biosynthetic process
HT132_RS04760	COG0842	Transport permease protein
HT132_RS04770	COG1131	(ABC) transporter
HT132_RS04775	COG3850	Histidine kinase
HT132_RS04780	COG2197	response regulator
HT132_RS04785	COG4149	molybdate abc transporter
HT132_RS04790	COG0725	ABC transporter, periplasmic molybdate-binding protein
HT132_RS04795	COG1910	domain protein
HT132_RS04800	COG1368	sulfuric ester hydrolase activity
HT132_RS04805	COG1988	membrane-bound metal-dependent
HT132_RS04815	COG0531	amino acid
HT132_RS04820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HT132_RS04825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_RS04830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS04840	COG1120	ATPase activity
HT132_RS04850	COG2140	Oxalate decarboxylase
HT132_RS04860	COG1191	sigma factor activity
HT132_RS04870	COG0745	RESPONSE REGULATOR receiver
HT132_RS04875	COG2205	protein histidine kinase activity
HT132_RS04880	COG3386	PFAM SMP-30 Gluconolaconase
HT132_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS04890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_RS04895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS04900	COG1120	ATPase activity
HT132_RS04905	COG2096	Adenosyltransferase
HT132_RS04910	COG2814	Major facilitator Superfamily
HT132_RS04915	COG4758	membrane
HT132_RS04920	COG1842	Phage shock protein A
HT132_RS04925	COG3595	metallopeptidase activity
HT132_RS04930	COG4758	membrane
HT132_RS04935	COG4585	Histidine kinase
HT132_RS04940	COG2197	response regulator
HT132_RS04950	COG0814	amino acid
HT132_RS04955	COG0697	spore germination
HT132_RS04965	COG0114	fumarate hydratase activity
HT132_RS04970	COG1309	transcriptional regulator
HT132_RS04980	COG2770	Histidine kinase
HT132_RS04980	COG2205	protein histidine kinase activity
HT132_RS04985	COG0745	RESPONSE REGULATOR receiver
HT132_RS04990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_RS04995	COG0783	Belongs to the Dps family
HT132_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS05015	COG1120	ATPase activity
HT132_RS05035	COG0583	DNA-binding transcription factor activity
HT132_RS05040	COG0477	Major facilitator Superfamily
HT132_RS05045	COG1846	Transcriptional regulator
HT132_RS05050	COG5577	PFAM Coat F domain
HT132_RS05070	COG1250	3-hydroxyacyl-CoA dehydrogenase
HT132_RS05070	COG1024	Enoyl-CoA hydratase
HT132_RS05075	COG0183	Belongs to the thiolase family
HT132_RS05080	COG1960	acyl-CoA dehydrogenase activity
HT132_RS05085	COG1393	Belongs to the ArsC family
HT132_RS05100	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HT132_RS05105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS05115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HT132_RS05120	COG2011	ABC-type metal ion transport system permease component
HT132_RS05125	COG1464	Belongs to the NlpA lipoprotein family
HT132_RS05130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HT132_RS05140	COG0396	ATPase activity
HT132_RS05145	COG0719	Fe-S assembly protein
HT132_RS05150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HT132_RS05155	COG0822	iron-sulfur transferase activity
HT132_RS05160	COG0719	Fe-S assembly protein
HT132_RS05165	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS05175	COG2226	methyltransferase
HT132_RS05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_RS05185	COG0322	excinuclease ABC activity
HT132_RS05210	COG0789	Transcriptional regulator
HT132_RS05215	COG2222	sugar isomerase
HT132_RS05220	COG1653	transport
HT132_RS05225	COG1175	transmembrane transport
HT132_RS05230	COG0395	ABC-type sugar transport system, permease component
HT132_RS05235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_RS05240	COG2188	Transcriptional regulator
HT132_RS05245	COG3842	ATPase activity
HT132_RS05250	COG2356	endonuclease I
HT132_RS05255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_RS05260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HT132_RS05265	COG2814	Major facilitator Superfamily
HT132_RS05275	COG0457	Tetratricopeptide repeat
HT132_RS05280	COG2508	Transcriptional regulator
HT132_RS05295	COG1801	Protein of unknown function DUF72
HT132_RS05300	COG0730	response to heat
HT132_RS05305	COG0737	Belongs to the 5'-nucleotidase family
HT132_RS05315	COG0739	heme binding
HT132_RS05325	COG4470	Protein conserved in bacteria
HT132_RS05330	COG2445	Protein of unknown function DUF86
HT132_RS05335	COG0647	UMP catabolic process
HT132_RS05340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HT132_RS05345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_RS05350	COG0460	homoserine dehydrogenase
HT132_RS05355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HT132_RS05365	COG0823	Involved in the tonB-independent uptake of proteins
HT132_RS05365	COG1506	peptidase
HT132_RS05365	COG4946	Tricorn protease homolog
HT132_RS05370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HT132_RS05375	COG4837	Protein of unknown function (DUF1462)
HT132_RS05380	COG1252	NADH dehydrogenase
HT132_RS05390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HT132_RS05400	COG0316	Belongs to the HesB IscA family
HT132_RS05405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HT132_RS05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_RS05430	COG1131	(ABC) transporter
HT132_RS05460	COG1252	NADH dehydrogenase
HT132_RS05475	COG3584	3D domain protein
HT132_RS05480	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HT132_RS05490	COG2056	Na+-H+ antiporter family
HT132_RS05495	COG1268	BioY protein
HT132_RS05500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HT132_RS05505	COG2819	hydrolase of the alpha beta superfamily
HT132_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS05515	COG1169	isochorismate synthase
HT132_RS05520	COG1021	2,3-dihydroxybenzoate-AMP ligase
HT132_RS05525	COG3433	isochorismatase activity
HT132_RS05525	COG1535	isochorismatase
HT132_RS05530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS05535	COG3251	PFAM MbtH domain protein
HT132_RS05540	COG5634	Uncharacterized conserved protein (DUF2278)
HT132_RS05545	COG0686	Belongs to the AlaDH PNT family
HT132_RS05550	COG2508	Transcriptional regulator
HT132_RS05550	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HT132_RS05555	COG4842	Belongs to the WXG100 family
HT132_RS05560	COG5417	Belongs to the EsaB family
HT132_RS05565	COG4499	WXG100 protein secretion system (Wss), protein YukC
HT132_RS05570	COG0433	COG0433 Predicted ATPase
HT132_RS05570	COG1674	ftsk spoiiie
HT132_RS05575	COG1511	domain protein
HT132_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS05590	COG1418	mRNA catabolic process
HT132_RS05600	COG0628	permease
HT132_RS05615	COG5506	Protein of unknown function (DUF1694)
HT132_RS05620	COG1335	isochorismatase
HT132_RS05625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HT132_RS05630	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HT132_RS05645	COG0142	geranyltranstransferase activity
HT132_RS05655	COG4585	Histidine kinase
HT132_RS05660	COG2197	response regulator
HT132_RS05665	COG2050	protein possibly involved in aromatic compounds catabolism
HT132_RS05670	COG1320	monovalent cation:proton antiporter activity
HT132_RS05675	COG2212	antiporter activity
HT132_RS05680	COG1863	multisubunit Na H antiporter MnhE subunit
HT132_RS05690	COG1006	Multisubunit Na H antiporter MnhC subunit
HT132_RS05695	COG2111	Na H antiporter
HT132_RS05700	COG2111	Na H antiporter
HT132_RS05700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HT132_RS05730	COG4565	transcriptional regulatory protein
HT132_RS05735	COG3290	protein histidine kinase activity
HT132_RS05745	COG3011	Protein conserved in bacteria
HT132_RS05750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_RS05755	COG2814	Major facilitator Superfamily
HT132_RS05760	COG5018	Exonuclease
HT132_RS05770	COG2205	protein histidine kinase activity
HT132_RS05775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HT132_RS05785	COG2267	carboxylic ester hydrolase activity
HT132_RS05790	COG1522	sequence-specific DNA binding
HT132_RS05795	COG0436	Aminotransferase
HT132_RS05800	COG1098	S1 RNA binding domain
HT132_RS05805	COG2155	Conserved Protein
HT132_RS05810	COG1979	alcohol dehydrogenase
HT132_RS05815	COG1979	alcohol dehydrogenase
HT132_RS05820	COG1335	isochorismatase
HT132_RS05845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HT132_RS05860	COG2738	Putative neutral zinc metallopeptidase
HT132_RS05865	COG1253	flavin adenine dinucleotide binding
HT132_RS05870	COG0366	Alpha amylase catalytic
HT132_RS05875	COG0432	Pfam Uncharacterised protein family UPF0047
HT132_RS05880	COG2070	2-Nitropropane dioxygenase
HT132_RS05895	COG0840	transmembrane signaling receptor activity
HT132_RS05900	COG0840	transmembrane signaling receptor activity
HT132_RS05905	COG0840	transmembrane signaling receptor activity
HT132_RS05910	COG0840	transmembrane signaling receptor activity
HT132_RS05915	COG0693	protein deglycase activity
HT132_RS05920	COG0673	inositol 2-dehydrogenase activity
HT132_RS05925	COG0628	permease
HT132_RS05950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HT132_RS05950	COG1017	nitric oxide dioxygenase activity
HT132_RS05955	COG1705	Flagellar rod assembly protein muramidase FlgJ
HT132_RS05960	COG0569	domain protein
HT132_RS05970	COG1510	regulation of RNA biosynthetic process
HT132_RS05975	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS05980	COG1454	alcohol dehydrogenase
HT132_RS05990	COG2318	DinB family
HT132_RS05995	COG1585	Membrane protein implicated in regulation of membrane protease activity
HT132_RS06000	COG2268	Band 7 protein
HT132_RS06005	COG3859	Proton-coupled thiamine transporter YuaJ
HT132_RS06130	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HT132_RS06135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_RS06140	COG1169	isochorismate synthase
HT132_RS06150	COG0596	Alpha beta hydrolase
HT132_RS06155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HT132_RS06165	COG4948	Mandelate Racemase Muconate Lactonizing
HT132_RS06170	COG0803	Belongs to the bacterial solute-binding protein 9 family
HT132_RS06175	COG1121	(ABC) transporter
HT132_RS06180	COG1321	iron dependent repressor
HT132_RS06180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_RS06185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_RS06195	COG1294	oxidase, subunit
HT132_RS06200	COG1271	oxidase subunit
HT132_RS06210	COG0288	reversible hydration of carbon dioxide
HT132_RS06235	COG0783	Belongs to the Dps family
HT132_RS06240	COG4824	toxin secretion phage lysis holin
HT132_RS06245	COG0494	nUDIX hydrolase
HT132_RS06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HT132_RS06255	COG1116	anion transmembrane transporter activity
HT132_RS06260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HT132_RS06265	COG1506	peptidase
HT132_RS06285	COG0367	asparagine synthase
HT132_RS06290	COG1113	amino acid transport
HT132_RS06295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HT132_RS06300	COG2267	carboxylic ester hydrolase activity
HT132_RS06310	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_RS06320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HT132_RS06325	COG1242	4 iron, 4 sulfur cluster binding
HT132_RS06335	COG1725	Transcriptional regulator
HT132_RS06340	COG1131	(ABC) transporter
HT132_RS06360	COG1136	(ABC) transporter
HT132_RS06365	COG0577	efflux transmembrane transporter activity
HT132_RS06370	COG0745	RESPONSE REGULATOR receiver
HT132_RS06375	COG2205	protein histidine kinase activity
HT132_RS06380	COG1136	(ABC) transporter
HT132_RS06385	COG0577	efflux transmembrane transporter activity
HT132_RS06390	COG5522	Integral membrane protein (intg_mem_TP0381)
HT132_RS06395	COG2814	Major facilitator Superfamily
HT132_RS06400	COG2202	Pas domain
HT132_RS06400	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS06415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_RS06425	COG1486	melibiose metabolic process
HT132_RS06430	COG0395	ABC-type sugar transport system, permease component
HT132_RS06435	COG1175	transmembrane transport
HT132_RS06440	COG1653	transport
HT132_RS06445	COG1609	Transcriptional regulator
HT132_RS06455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HT132_RS06460	COG2081	HI0933 family
HT132_RS06465	COG2244	polysaccharide biosynthetic process
HT132_RS06470	COG1187	pseudouridine synthase activity
HT132_RS06475	COG1349	DNA-binding transcription factor activity
HT132_RS06480	COG1131	(ABC) transporter
HT132_RS06485	COG4473	ABC transporter
HT132_RS06490	COG2252	PERMEase
HT132_RS06495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_RS06500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_RS06505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HT132_RS06515	COG1597	lipid kinase activity
HT132_RS06520	COG0510	thiamine kinase activity
HT132_RS06535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS06540	COG0281	malic enzyme
HT132_RS06545	COG5584	Small secreted protein
HT132_RS06550	COG1363	Peptidase, m42
HT132_RS06560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS06570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_RS06575	COG1674	ftsk spoiiie
HT132_RS06585	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HT132_RS06590	COG4980	gas vesicle protein
HT132_RS06595	COG3118	belongs to the thioredoxin family
HT132_RS06600	COG1605	Chorismate mutase
HT132_RS06600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HT132_RS06605	COG1609	Transcriptional regulator
HT132_RS06610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HT132_RS06615	COG1360	Flagellar Motor Protein
HT132_RS06620	COG0123	including yeast histone deacetylase and acetoin utilization protein
HT132_RS06625	COG0517	IMP dehydrogenase activity
HT132_RS06630	COG0454	-acetyltransferase
HT132_RS06635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HT132_RS06655	COG1378	Sugar-specific transcriptional regulator TrmB
HT132_RS06660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_RS06675	COG0693	protein deglycase activity
HT132_RS06690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HT132_RS06690	COG1017	nitric oxide dioxygenase activity
HT132_RS06710	COG0457	Tetratricopeptide repeat
HT132_RS06715	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS06725	COG2203	Gaf domain
HT132_RS06725	COG2199	diguanylate cyclase activity
HT132_RS06730	COG1956	GAF domain-containing protein
HT132_RS06735	COG1309	transcriptional regulator
HT132_RS06740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HT132_RS06750	COG1114	Component of the transport system for branched-chain amino acids
HT132_RS06755	COG1104	cysteine desulfurase activity
HT132_RS06770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HT132_RS06775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HT132_RS06780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HT132_RS06785	COG0616	signal peptide processing
HT132_RS06790	COG1714	RDD family
HT132_RS06800	COG3874	Sporulation protein YtfJ
HT132_RS06805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HT132_RS06810	COG0827	DNA restriction-modification system
HT132_RS06820	COG0521	Mo-molybdopterin cofactor biosynthetic process
HT132_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS06845	COG4109	DRTGG domain
HT132_RS06855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HT132_RS06875	COG0587	DNA-directed DNA polymerase activity
HT132_RS06880	COG0281	malic enzyme
HT132_RS06900	COG0469	pyruvate kinase activity
HT132_RS06905	COG3030	protein affecting phage T7 exclusion by the F plasmid
HT132_RS06910	COG0628	permease
HT132_RS06935	COG0457	Tetratricopeptide repeat
HT132_RS06945	COG0372	Belongs to the citrate synthase family
HT132_RS06950	COG0538	isocitrate dehydrogenase activity
HT132_RS06960	COG0745	RESPONSE REGULATOR receiver
HT132_RS06965	COG5002	protein histidine kinase activity
HT132_RS06970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_RS06970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_RS06975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HT132_RS06980	COG1971	Probably functions as a manganese efflux pump
HT132_RS06985	COG0237	dephospho-CoA kinase activity
HT132_RS06990	COG0656	L-ascorbic acid biosynthetic process
HT132_RS06995	COG2814	Major facilitator Superfamily
HT132_RS07000	COG1733	regulation of RNA biosynthetic process
HT132_RS07005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HT132_RS07020	COG3611	Membrane attachment protein
HT132_RS07025	COG1484	DNA-dependent DNA replication
HT132_RS07030	COG0398	Pfam SNARE associated Golgi protein
HT132_RS07045	COG1011	Hydrolase
HT132_RS07050	COG3275	phosphorelay sensor kinase activity
HT132_RS07055	COG3279	Response regulator of the LytR AlgR family
HT132_RS07060	COG1380	Effector of murein hydrolase LrgA
HT132_RS07065	COG1346	cytolysis
HT132_RS07070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HT132_RS07085	COG3326	Membrane
HT132_RS07095	COG1363	Peptidase, m42
HT132_RS07100	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_RS07105	COG2160	L-arabinose isomerase activity
HT132_RS07110	COG1069	ribulokinase activity
HT132_RS07115	COG0235	Class ii aldolase
HT132_RS07120	COG0647	UMP catabolic process
HT132_RS07130	COG1653	transport
HT132_RS07135	COG1175	transmembrane transport
HT132_RS07140	COG0395	ABC-type sugar transport system, permease component
HT132_RS07145	COG3534	alpha-L-arabinofuranosidase
HT132_RS07150	COG1966	Carbon starvation protein
HT132_RS07155	COG0247	lactate metabolic process
HT132_RS07160	COG0277	FAD linked oxidase domain protein
HT132_RS07165	COG3835	regulator
HT132_RS07175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HT132_RS07180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HT132_RS07185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_RS07185	COG0072	phenylalanine-tRNA ligase activity
HT132_RS07200	COG1286	toxin biosynthetic process
HT132_RS07205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HT132_RS07205	COG1796	DNA polymerase
HT132_RS07215	COG3766	membrane
HT132_RS07225	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS07230	COG1309	transcriptional regulator
HT132_RS07235	COG1024	Enoyl-CoA hydratase
HT132_RS07240	COG2086	electron transfer activity
HT132_RS07245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HT132_RS07250	COG3534	alpha-L-arabinofuranosidase
HT132_RS07255	COG3118	belongs to the thioredoxin family
HT132_RS07265	COG0527	aspartate kinase activity
HT132_RS07270	COG1719	4-vinyl reductase, 4VR
HT132_RS07275	COG2009	succinate dehydrogenase
HT132_RS07280	COG1053	succinate dehydrogenase
HT132_RS07285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HT132_RS07290	COG0824	Thioesterase
HT132_RS07295	COG2197	response regulator
HT132_RS07300	COG1846	Transcriptional regulator
HT132_RS07310	COG5401	PFAM Sporulation and spore germination
HT132_RS07320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HT132_RS07325	COG0622	Phosphoesterase
HT132_RS07350	COG0028	Belongs to the TPP enzyme family
HT132_RS07355	COG0440	acetolactate synthase activity
HT132_RS07370	COG0473	3-isopropylmalate dehydrogenase activity
HT132_RS07385	COG0457	Tetratricopeptide repeat
HT132_RS07385	COG1477	protein flavinylation
HT132_RS07400	COG0470	DNA polymerase III
HT132_RS07400	COG1067	ATP-dependent peptidase activity
HT132_RS07405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HT132_RS07425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HT132_RS07435	COG1587	Uroporphyrinogen-III synthase
HT132_RS07440	COG0113	porphobilinogen synthase activity
HT132_RS07450	COG1388	LysM domain
HT132_RS07455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_RS07465	COG0525	valine-tRNA ligase activity
HT132_RS07470	COG0285	dihydrofolate synthase activity
HT132_RS07475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HT132_RS07495	COG1077	Cell shape determining protein MreB Mrl
HT132_RS07505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HT132_RS07515	COG2894	cell division
HT132_RS07520	COG0739	heme binding
HT132_RS07525	COG1994	Peptidase M50
HT132_RS07535	COG2868	ribosomal protein
HT132_RS07540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HT132_RS07545	COG3290	protein histidine kinase activity
HT132_RS07560	COG0077	Prephenate dehydratase
HT132_RS07565	COG1827	regulation of RNA biosynthetic process
HT132_RS07570	COG1104	cysteine desulfurase activity
HT132_RS07575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HT132_RS07580	COG0157	Belongs to the NadC ModD family
HT132_RS07590	COG1388	LysM domain
HT132_RS07630	COG1862	Preprotein translocase
HT132_RS07640	COG2323	membrane
HT132_RS07645	COG2244	polysaccharide biosynthetic process
HT132_RS07655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HT132_RS07655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HT132_RS07660	COG0490	domain, Protein
HT132_RS07665	COG5416	Lipopolysaccharide assembly protein A domain
HT132_RS07670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HT132_RS07670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HT132_RS07680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HT132_RS07690	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS07690	COG3103	Sh3 type 3 domain protein
HT132_RS07690	COG4991	sh3 domain protein
HT132_RS07715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HT132_RS07720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HT132_RS07725	COG1959	2 iron, 2 sulfur cluster binding
HT132_RS07730	COG1104	cysteine desulfurase activity
HT132_RS07740	COG0457	Tetratricopeptide repeat
HT132_RS07745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HT132_RS07750	COG3881	PFAM PRC-barrel domain
HT132_RS07765	COG0765	amino acid transport
HT132_RS07770	COG0765	amino acid transport
HT132_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS07780	COG1126	abc transporter atp-binding protein
HT132_RS07785	COG0628	permease
HT132_RS07795	COG4472	Bacterial protein of unknown function (DUF965)
HT132_RS07810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HT132_RS07815	COG4122	O-methyltransferase activity
HT132_RS07840	COG0768	penicillin binding
HT132_RS07865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HT132_RS07870	COG0626	cystathionine gamma-synthase activity
HT132_RS07880	COG2427	Protein of unknown function (DUF1641)
HT132_RS07885	COG3383	formate dehydrogenase (NAD+) activity
HT132_RS07890	COG5609	conserved protein (DUF2294)
HT132_RS07895	COG2116	formate transmembrane transporter activity
HT132_RS07910	COG2226	methyltransferase
HT132_RS07915	COG1309	transcriptional regulator
HT132_RS07920	COG2124	cytochrome p450
HT132_RS07920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_RS07925	COG2814	Major facilitator Superfamily
HT132_RS07930	COG0583	DNA-binding transcription factor activity
HT132_RS07935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HT132_RS07945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS07945	COG3711	transcriptional antiterminator
HT132_RS07950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_RS07950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS07950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_RS07955	COG1482	cell wall glycoprotein biosynthetic process
HT132_RS07965	COG0561	phosphatase activity
HT132_RS07970	COG0561	phosphatase activity
HT132_RS07980	COG2318	DinB family
HT132_RS07985	COG0456	acetyltransferase
HT132_RS08005	COG0563	adenylate kinase activity
HT132_RS08010	COG0454	-acetyltransferase
HT132_RS08020	COG2311	Membrane
HT132_RS08025	COG0745	RESPONSE REGULATOR receiver
HT132_RS08030	COG5002	protein histidine kinase activity
HT132_RS08030	COG0642	Histidine kinase
HT132_RS08055	COG2856	Zn peptidase
HT132_RS08060	COG0457	Tetratricopeptide repeat
HT132_RS08080	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_RS08080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_RS08090	COG0477	Major facilitator Superfamily
HT132_RS08105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_RS08110	COG0473	3-isopropylmalate dehydrogenase activity
HT132_RS08110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_RS08115	COG0473	3-isopropylmalate dehydrogenase activity
HT132_RS08115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HT132_RS08120	COG1802	Transcriptional regulator
HT132_RS08130	COG0583	DNA-binding transcription factor activity
HT132_RS08135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_RS08155	COG0398	Pfam SNARE associated Golgi protein
HT132_RS08165	COG2755	lipolytic protein G-D-S-L family
HT132_RS08175	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HT132_RS08180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HT132_RS08185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HT132_RS08190	COG1534	Rna-binding protein
HT132_RS08200	COG1713	HD superfamily hydrolase involved in NAD metabolism
HT132_RS08205	COG0799	negative regulation of ribosome biogenesis
HT132_RS08210	COG2226	methyltransferase
HT132_RS08215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HT132_RS08220	COG1555	photosystem II stabilization
HT132_RS08220	COG1596	polysaccharide export
HT132_RS08225	COG2131	deaminase
HT132_RS08230	COG2333	competence protein COMEC
HT132_RS08230	COG0658	competence protein
HT132_RS08245	COG1466	dna polymerase III delta subunit
HT132_RS08260	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS08275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HT132_RS08305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HT132_RS08310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HT132_RS08315	COG1283	sodium-dependent phosphate transmembrane transporter activity
HT132_RS08325	COG1610	YqeY-like protein
HT132_RS08330	COG1030	water channel activity
HT132_RS08335	COG4864	UPF0365 protein
HT132_RS08350	COG0561	phosphatase activity
HT132_RS08355	COG1702	phosphate starvation-inducible protein PhoH
HT132_RS08360	COG1480	7TM receptor with intracellular HD hydrolase
HT132_RS08370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HT132_RS08375	COG0295	cytidine deaminase activity
HT132_RS08380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HT132_RS08400	COG0751	glycine-tRNA ligase activity
HT132_RS08405	COG0517	IMP dehydrogenase activity
HT132_RS08420	COG0358	DNA primase activity
HT132_RS08425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HT132_RS08430	COG2010	Cytochrome c
HT132_RS08435	COG2384	SAM-dependent methyltransferase
HT132_RS08440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HT132_RS08455	COG0513	Belongs to the DEAD box helicase family
HT132_RS08470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS08475	COG0735	belongs to the Fur family
HT132_RS08480	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HT132_RS08485	COG4709	membrane
HT132_RS08495	COG1388	LysM domain
HT132_RS08500	COG5521	maltodextrose utilization protein MalA
HT132_RS08505	COG2839	Protein conserved in bacteria
HT132_RS08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HT132_RS08515	COG0477	Major facilitator Superfamily
HT132_RS08525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HT132_RS08530	COG0573	inorganic phosphate transmembrane transporter activity
HT132_RS08535	COG0581	inorganic phosphate transmembrane transporter activity
HT132_RS08540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_RS08545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_RS08550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HT132_RS08565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HT132_RS08575	COG1757	Na H antiporter
HT132_RS08580	COG4483	Protein conserved in bacteria
HT132_RS08585	COG1940	carbohydrate kinase activity
HT132_RS08590	COG2866	Carboxypeptidase
HT132_RS08600	COG0011	TIGRFAM Protein of
HT132_RS08610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS08620	COG1393	Belongs to the ArsC family
HT132_RS08630	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS08635	COG1253	flavin adenine dinucleotide binding
HT132_RS08640	COG0598	Magnesium transport protein CorA
HT132_RS08645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HT132_RS08650	COG1459	type II secretion system
HT132_RS08655	COG4537	Required for transformation and DNA binding
HT132_RS08660	COG4970	Tfp pilus assembly protein FimT
HT132_RS08670	COG4940	Competence protein ComGF
HT132_RS08695	COG0681	Belongs to the peptidase S26 family
HT132_RS08705	COG1396	sequence-specific DNA binding
HT132_RS08720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HT132_RS08740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_RS08755	COG1752	Esterase of the alpha-beta hydrolase superfamily
HT132_RS08765	COG3872	metal-dependent enzyme
HT132_RS08775	COG0006	proline dipeptidase activity
HT132_RS08790	COG3854	ATPases associated with a variety of cellular activities
HT132_RS08830	COG0511	ligase activity, forming carbon-carbon bonds
HT132_RS08835	COG0439	Biotin carboxylase
HT132_RS08840	COG1302	Protein conserved in bacteria
HT132_RS08855	COG1570	exodeoxyribonuclease VII activity
HT132_RS08865	COG0142	geranyltranstransferase activity
HT132_RS08875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HT132_RS08885	COG0497	DNA recombination
HT132_RS08890	COG0750	zinc metalloprotease
HT132_RS08895	COG0745	RESPONSE REGULATOR receiver
HT132_RS08900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HT132_RS08915	COG1902	pentaerythritol trinitrate reductase activity
HT132_RS08940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS08945	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_RS08950	COG0183	Belongs to the thiolase family
HT132_RS08955	COG1250	3-hydroxyacyl-CoA dehydrogenase
HT132_RS08960	COG1960	acyl-CoA dehydrogenase activity
HT132_RS08965	COG0372	Belongs to the citrate synthase family
HT132_RS08970	COG2079	MmgE PrpD family protein
HT132_RS08975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HT132_RS08985	COG3290	protein histidine kinase activity
HT132_RS08985	COG3829	transcription factor binding
HT132_RS08990	COG0280	phosphate acetyltransferase
HT132_RS08995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_RS09000	COG3426	butyrate kinase activity
HT132_RS09005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_RS09010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_RS09015	COG0022	dehydrogenase e1 component
HT132_RS09020	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_RS09025	COG1597	lipid kinase activity
HT132_RS09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS09040	COG0765	amino acid transport
HT132_RS09045	COG1126	abc transporter atp-binding protein
HT132_RS09050	COG4129	membrane
HT132_RS09055	COG1376	ErfK ybiS ycfS ynhG family protein
HT132_RS09065	COG0346	lactoylglutathione lyase activity
HT132_RS09070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HT132_RS09075	COG2195	Cleaves the N-terminal amino acid of tripeptides
HT132_RS09080	COG0706	membrane insertase activity
HT132_RS09095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HT132_RS09100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HT132_RS09115	COG0596	Alpha beta hydrolase
HT132_RS09140	COG0250	Participates in transcription elongation, termination and antitermination
HT132_RS09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HT132_RS09145	COG2070	2-Nitropropane dioxygenase
HT132_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09175	COG0300	oxidoreductase activity
HT132_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09175	COG3321	synthase
HT132_RS09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09180	COG3321	synthase
HT132_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09185	COG3321	synthase
HT132_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09185	COG0300	oxidoreductase activity
HT132_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09190	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS09190	COG0300	oxidoreductase activity
HT132_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09190	COG3321	synthase
HT132_RS09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS09195	COG3321	synthase
HT132_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS09200	COG3321	synthase
HT132_RS09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS09200	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS09200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS09205	COG2124	cytochrome p450
HT132_RS09210	COG3425	synthase
HT132_RS09215	COG1024	Enoyl-CoA hydratase
HT132_RS09220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HT132_RS09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS09230	COG0300	oxidoreductase activity
HT132_RS09235	COG3048	D-serine ammonia-lyase activity
HT132_RS09245	COG0346	lactoylglutathione lyase activity
HT132_RS09255	COG0628	permease
HT132_RS09270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HT132_RS09275	COG0456	acetyltransferase
HT132_RS09280	COG2329	Antibiotic biosynthesis monooxygenase
HT132_RS09285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HT132_RS09285	COG0456	acetyltransferase
HT132_RS09290	COG4918	Iron-sulphur cluster biosynthesis
HT132_RS09300	COG1073	alpha beta
HT132_RS09310	COG0667	Aldo Keto reductase
HT132_RS09320	COG0494	nUDIX hydrolase
HT132_RS09325	COG1379	DNA repair
HT132_RS09330	COG1396	sequence-specific DNA binding
HT132_RS09335	COG0252	asparaginase activity
HT132_RS09340	COG1027	Aspartate ammonia-lyase
HT132_RS09345	COG1757	Na H antiporter
HT132_RS09350	COG0281	malic enzyme
HT132_RS09365	COG1300	Membrane
HT132_RS09370	COG0735	belongs to the Fur family
HT132_RS09380	COG4974	Belongs to the 'phage' integrase family
HT132_RS09385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HT132_RS09390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HT132_RS09400	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS09410	COG1191	sigma factor activity
HT132_RS09430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_RS09445	COG0697	spore germination
HT132_RS09450	COG0019	diaminopimelate decarboxylase activity
HT132_RS09455	COG4086	secreted protein
HT132_RS09460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HT132_RS09470	COG0681	Belongs to the peptidase S26 family
HT132_RS09480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HT132_RS09480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HT132_RS09485	COG0307	riboflavin synthase, alpha
HT132_RS09500	COG0456	acetyltransferase
HT132_RS09505	COG1547	Domain of unknown function (DUF309)
HT132_RS09530	COG1686	Belongs to the peptidase S11 family
HT132_RS09535	COG2715	membrane protein required for spore maturation
HT132_RS09540	COG0700	Nucleoside recognition
HT132_RS09545	COG1187	pseudouridine synthase activity
HT132_RS09550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS09555	COG1333	cytochrome c biogenesis protein
HT132_RS09560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HT132_RS09565	COG0745	RESPONSE REGULATOR receiver
HT132_RS09570	COG5002	protein histidine kinase activity
HT132_RS09575	COG1595	DNA-templated transcription, initiation
HT132_RS09590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HT132_RS09595	COG1141	Ferredoxin
HT132_RS09600	COG4955	Helix-turn-helix domain
HT132_RS09605	COG0514	ATP-dependent DNA helicase (RecQ)
HT132_RS09610	COG1266	CAAX protease self-immunity
HT132_RS09615	COG1388	LysM domain
HT132_RS09625	COG1408	metallophosphoesterase
HT132_RS09630	COG4862	establishment of competence for transformation
HT132_RS09635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HT132_RS09640	COG0492	ferredoxin-NADP+ reductase activity
HT132_RS09645	COG2339	peptidase activity
HT132_RS09650	COG3773	Cell wall hydrolase
HT132_RS09650	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS09655	COG2959	enzyme of heme biosynthesis
HT132_RS09660	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HT132_RS09675	COG0539	negative regulation of cytoplasmic translation
HT132_RS09715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HT132_RS09720	COG0776	regulation of translation
HT132_RS09735	COG0142	geranyltranstransferase activity
HT132_RS09745	COG0142	geranyltranstransferase activity
HT132_RS09750	COG0105	UTP biosynthetic process
HT132_RS09755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HT132_RS09770	COG4401	Chorismate mutase type I
HT132_RS09775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HT132_RS09810	COG0287	Prephenate dehydrogenase
HT132_RS09820	COG0457	Tetratricopeptide repeat
HT132_RS09835	COG0723	plastoquinol--plastocyanin reductase activity
HT132_RS09840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HT132_RS09845	COG2010	Cytochrome c
HT132_RS09845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HT132_RS09850	COG4347	Protein of unknown function (DUF1405)
HT132_RS09860	COG2140	Oxalate decarboxylase
HT132_RS09865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS09870	COG1694	Mazg nucleotide pyrophosphohydrolase
HT132_RS09885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_RS09890	COG0438	transferase activity, transferring glycosyl groups
HT132_RS09920	COG1199	ATP-dependent helicase activity
HT132_RS09920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HT132_RS09930	COG5353	protein conserved in bacteria
HT132_RS09935	COG0436	Aminotransferase
HT132_RS09945	COG3935	DnaD domain protein
HT132_RS09950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HT132_RS09960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_RS09960	COG4499	WXG100 protein secretion system (Wss), protein YukC
HT132_RS10000	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_RS10005	COG2190	(PTS) system
HT132_RS10010	COG1111	helicase
HT132_RS10010	COG1205	dead DEAH box helicase
HT132_RS10015	COG3359	exonuclease
HT132_RS10045	COG0116	Belongs to the methyltransferase superfamily
HT132_RS10060	COG1199	ATP-dependent helicase activity
HT132_RS10065	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HT132_RS10075	COG2233	PERMEase
HT132_RS10080	COG0582	viral genome integration into host DNA
HT132_RS10085	COG3620	sequence-specific DNA binding
HT132_RS10100	COG3646	Phage regulatory protein
HT132_RS10100	COG3645	SOS response
HT132_RS10135	COG3935	DnaD domain protein
HT132_RS10140	COG1484	DNA-dependent DNA replication
HT132_RS10145	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HT132_RS10175	COG1595	DNA-templated transcription, initiation
HT132_RS10280	COG5280	Phage tail tape measure protein TP901
HT132_RS10280	COG3953	SLT domain
HT132_RS10290	COG1705	Flagellar rod assembly protein muramidase FlgJ
HT132_RS10295	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_RS10315	COG4824	toxin secretion phage lysis holin
HT132_RS10360	COG1335	isochorismatase
HT132_RS10380	COG3424	synthase
HT132_RS10385	COG1755	Isoprenylcysteine carboxyl methyltransferase
HT132_RS10395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HT132_RS10410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HT132_RS10420	COG0328	RNA-DNA hybrid ribonuclease activity
HT132_RS10425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HT132_RS10430	COG0328	RNA-DNA hybrid ribonuclease activity
HT132_RS10450	COG1278	Cold shock
HT132_RS10460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HT132_RS10470	COG0386	Belongs to the glutathione peroxidase family
HT132_RS10475	COG1418	mRNA catabolic process
HT132_RS10480	COG1413	lyase activity
HT132_RS10495	COG2521	methyltransferase
HT132_RS10495	COG2136	Putative SAM-dependent methyltransferase
HT132_RS10510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HT132_RS10515	COG0204	Acyl-transferase
HT132_RS10520	COG1272	protein, Hemolysin III
HT132_RS10525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HT132_RS10530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HT132_RS10540	COG1999	signal sequence binding
HT132_RS10545	COG2755	lipolytic protein G-D-S-L family
HT132_RS10550	COG4698	Protein conserved in bacteria
HT132_RS10555	COG1846	Transcriptional regulator
HT132_RS10575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_RS10590	COG1525	nuclease
HT132_RS10595	COG4282	regulation of fungal-type cell wall biogenesis
HT132_RS10600	COG5444	nuclease activity
HT132_RS10625	COG0457	Tetratricopeptide repeat
HT132_RS10630	COG1388	LysM domain
HT132_RS10655	COG1086	Polysaccharide biosynthesis protein
HT132_RS10665	COG4641	Protein conserved in bacteria
HT132_RS10680	COG0463	Glycosyl transferase, family 2
HT132_RS10685	COG0456	acetyltransferase
HT132_RS10695	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HT132_RS10700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HT132_RS10705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HT132_RS10710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HT132_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_RS10720	COG0456	acetyltransferase
HT132_RS10725	COG1509	lysine 2,3-aminomutase activity
HT132_RS10755	COG0671	phosphoesterase, PA-phosphatase related
HT132_RS10775	COG1876	peptidase activity
HT132_RS10785	COG2226	methyltransferase
HT132_RS10790	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS10790	COG0793	Belongs to the peptidase S41A family
HT132_RS10795	COG2188	Transcriptional regulator
HT132_RS10800	COG2723	6-phospho-beta-galactosidase activity
HT132_RS10810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_RS10820	COG0346	lactoylglutathione lyase activity
HT132_RS10825	COG0400	carboxylic ester hydrolase activity
HT132_RS10830	COG0778	Nitroreductase
HT132_RS10835	COG1733	regulation of RNA biosynthetic process
HT132_RS10845	COG1942	4-Oxalocrotonate Tautomerase
HT132_RS10860	COG2962	Rard protein
HT132_RS10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_RS10875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HT132_RS10880	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS10885	COG0534	Mate efflux family protein
HT132_RS10890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HT132_RS10895	COG1819	glycosyl
HT132_RS10900	COG1388	LysM domain
HT132_RS10900	COG0791	NLP P60 protein
HT132_RS10905	COG2032	superoxide dismutase activity
HT132_RS10910	COG0714	Associated with various cellular activities
HT132_RS10915	COG4548	von Willebrand factor, type A
HT132_RS10925	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_RS10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS10935	COG0385	Bile acid
HT132_RS10940	COG0733	neurotransmitter:sodium symporter activity
HT132_RS10945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HT132_RS10950	COG1657	PFAM Prenyltransferase squalene oxidase
HT132_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS10985	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_RS11000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_RS11005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HT132_RS11015	COG0514	ATP-dependent DNA helicase (RecQ)
HT132_RS11020	COG1388	LysM domain
HT132_RS11020	COG3584	3D domain protein
HT132_RS11030	COG1619	proteins homologs of microcin C7 resistance protein MccF
HT132_RS11045	COG2322	membrane
HT132_RS11050	COG0741	lytic transglycosylase activity
HT132_RS11055	COG0640	Transcriptional regulator
HT132_RS11065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS11070	COG1309	transcriptional regulator
HT132_RS11075	COG0662	Cupin 2, conserved barrel domain protein
HT132_RS11075	COG2207	Transcriptional regulator
HT132_RS11080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HT132_RS11085	COG5444	nuclease activity
HT132_RS11115	COG0243	molybdopterin cofactor binding
HT132_RS11120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HT132_RS11125	COG1070	Carbohydrate kinase
HT132_RS11130	COG2814	Major facilitator Superfamily
HT132_RS11140	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HT132_RS11145	COG0300	oxidoreductase activity
HT132_RS11160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HT132_RS11165	COG0583	DNA-binding transcription factor activity
HT132_RS11170	COG0067	glutamate synthase
HT132_RS11170	COG0069	glutamate synthase activity
HT132_RS11170	COG0070	glutamate synthase
HT132_RS11175	COG0493	'glutamate synthase
HT132_RS11185	COG0604	alcohol dehydrogenase
HT132_RS11195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HT132_RS11200	COG0640	Transcriptional regulator
HT132_RS11205	COG2814	Major facilitator Superfamily
HT132_RS11210	COG0405	Gamma-glutamyltransferase
HT132_RS11215	COG0166	Belongs to the GPI family
HT132_RS11220	COG0582	viral genome integration into host DNA
HT132_RS11235	COG0534	Mate efflux family protein
HT132_RS11240	COG2017	converts alpha-aldose to the beta-anomer
HT132_RS11245	COG2027	D-alanyl-D-alanine carboxypeptidase
HT132_RS11250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11270	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HT132_RS11280	COG1649	PFAM Uncharacterised BCR, COG1649
HT132_RS11285	COG1960	acyl-CoA dehydrogenase activity
HT132_RS11290	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS11295	COG0439	Biotin carboxylase
HT132_RS11300	COG0511	ligase activity, forming carbon-carbon bonds
HT132_RS11305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HT132_RS11310	COG1024	Enoyl-CoA hydratase
HT132_RS11315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HT132_RS11320	COG0586	Pfam SNARE associated Golgi protein
HT132_RS11325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HT132_RS11330	COG2246	polysaccharide biosynthetic process
HT132_RS11340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HT132_RS11360	COG2124	cytochrome p450
HT132_RS11365	COG2610	gluconate transmembrane transporter activity
HT132_RS11370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HT132_RS11375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HT132_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11405	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_RS11415	COG0745	RESPONSE REGULATOR receiver
HT132_RS11420	COG2205	protein histidine kinase activity
HT132_RS11450	COG1136	(ABC) transporter
HT132_RS11450	COG0577	efflux transmembrane transporter activity
HT132_RS11480	COG1609	Transcriptional regulator
HT132_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11490	COG1312	Catalyzes the dehydration of D-mannonate
HT132_RS11495	COG0800	Aldolase
HT132_RS11500	COG1063	alcohol dehydrogenase
HT132_RS11510	COG1115	amino acid carrier protein
HT132_RS11520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HT132_RS11525	COG0187	DNA topoisomerase II activity
HT132_RS11530	COG1832	CoA-binding protein
HT132_RS11540	COG4841	protein insertion into membrane
HT132_RS11550	COG0824	Thioesterase
HT132_RS11570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS11575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HT132_RS11590	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_RS11600	COG4846	Membrane protein involved in cytochrome C biogenesis
HT132_RS11605	COG2201	protein-glutamate methylesterase activity
HT132_RS11610	COG0785	Cytochrome C biogenesis protein
HT132_RS11630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HT132_RS11640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HT132_RS11675	COG4195	phage-related replication protein
HT132_RS11680	COG0756	dUTP diphosphatase activity
HT132_RS11685	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_RS11705	COG3397	chitin binding
HT132_RS11735	COG1064	alcohol dehydrogenase
HT132_RS11740	COG2318	DinB family
HT132_RS11760	COG3848	Pyruvate phosphate dikinase
HT132_RS11760	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_RS11765	COG1070	Carbohydrate kinase
HT132_RS11780	COG3507	Belongs to the glycosyl hydrolase 43 family
HT132_RS11785	COG2211	Major facilitator Superfamily
HT132_RS11805	COG0174	glutamine synthetase
HT132_RS11810	COG0789	Transcriptional regulator
HT132_RS11815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HT132_RS11820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HT132_RS11825	COG0464	growth
HT132_RS11830	COG0860	N-Acetylmuramoyl-L-alanine amidase
HT132_RS11835	COG4112	unkown
HT132_RS11840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HT132_RS11845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HT132_RS11885	COG2076	Multidrug Resistance protein
HT132_RS11895	COG1764	response to oxidative stress
HT132_RS11900	COG4195	phage-related replication protein
HT132_RS11910	COG1404	Belongs to the peptidase S8 family
HT132_RS11920	COG3619	membrane
HT132_RS11925	COG3209	COG3209 Rhs family protein
HT132_RS11930	COG2124	cytochrome p450
HT132_RS11935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HT132_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS11935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HT132_RS11935	COG3321	synthase
HT132_RS11940	COG4221	oxidoreductase activity
HT132_RS11940	COG3321	synthase
HT132_RS11940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11945	COG3321	synthase
HT132_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS11945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS11945	COG3321	synthase
HT132_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11950	COG3321	synthase
HT132_RS11950	COG4221	oxidoreductase activity
HT132_RS11950	COG0300	oxidoreductase activity
HT132_RS11950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS11955	COG0300	oxidoreductase activity
HT132_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS11955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS11955	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS11955	COG3321	synthase
HT132_RS11960	COG1024	Enoyl-CoA hydratase
HT132_RS11965	COG1024	Enoyl-CoA hydratase
HT132_RS11970	COG3425	synthase
HT132_RS11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS12040	COG4550	Control of competence regulator ComK, YlbF/YmcA
HT132_RS12060	COG2359	stage V sporulation protein S
HT132_RS12065	COG1692	metallophosphoesterase
HT132_RS12075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_RS12090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HT132_RS12095	COG1426	Protein conserved in bacteria
HT132_RS12110	COG0300	oxidoreductase activity
HT132_RS12115	COG0612	Peptidase, M16
HT132_RS12120	COG0612	Peptidase, M16
HT132_RS12125	COG2409	Drug exporters of the RND superfamily
HT132_RS12125	COG1033	growth of symbiont in host cell
HT132_RS12130	COG1846	Transcriptional regulator
HT132_RS12135	COG2814	Major facilitator Superfamily
HT132_RS12140	COG2188	Transcriptional regulator
HT132_RS12145	COG1674	ftsk spoiiie
HT132_RS12145	COG4980	gas vesicle protein
HT132_RS12155	COG0740	serine-type endopeptidase activity
HT132_RS12160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HT132_RS12170	COG0527	aspartate kinase activity
HT132_RS12175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HT132_RS12180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HT132_RS12185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HT132_RS12190	COG1873	PFAM PRC-barrel domain
HT132_RS12195	COG0612	Peptidase, M16
HT132_RS12200	COG0726	polysaccharide deacetylase
HT132_RS12215	COG0196	riboflavin kinase activity
HT132_RS12230	COG1550	Protein conserved in bacteria
HT132_RS12240	COG1358	cellular component organization or biogenesis
HT132_RS12245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HT132_RS12250	COG0195	Participates in both transcription termination and antitermination
HT132_RS12260	COG2176	DNA-directed DNA polymerase activity
HT132_RS12270	COG0750	zinc metalloprotease
HT132_RS12280	COG4589	Belongs to the CDS family
HT132_RS12285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HT132_RS12315	COG1191	sigma factor activity
HT132_RS12325	COG1776	CheC inhibitor of MCP methylation
HT132_RS12330	COG0835	chemotaxis
HT132_RS12335	COG0643	Histidine kinase
HT132_RS12335	COG2198	Histidine kinase
HT132_RS12340	COG2201	protein-glutamate methylesterase activity
HT132_RS12345	COG0455	bacterial-type flagellum organization
HT132_RS12350	COG1419	protein localization to endoplasmic reticulum
HT132_RS12355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HT132_RS12360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HT132_RS12365	COG1684	flagellar biosynthetic protein fliR
HT132_RS12370	COG1987	bacterial-type flagellum assembly
HT132_RS12375	COG1338	Plays a role in the flagellum-specific transport system
HT132_RS12380	COG3190	flagellar
HT132_RS12385	COG2201	protein-glutamate methylesterase activity
HT132_RS12390	COG1776	CheC inhibitor of MCP methylation
HT132_RS12390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_RS12395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_RS12400	COG1580	Controls the rotational direction of flagella during chemotaxis
HT132_RS12405	COG1582	Flagellar protein (FlbD)
HT132_RS12410	COG4786	Flagellar basal body rod
HT132_RS12415	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HT132_RS12420	COG3144	bacterial-type flagellum assembly
HT132_RS12425	COG3334	PFAM MgtE intracellular
HT132_RS12430	COG2882	bacterial-type flagellum organization
HT132_RS12435	COG1157	protein secretion by the type III secretion system
HT132_RS12440	COG1317	bacterial-type flagellum organization
HT132_RS12445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HT132_RS12450	COG1766	The M ring may be actively involved in energy transduction
HT132_RS12455	COG1677	Flagellar hook-basal body complex protein FliE
HT132_RS12460	COG1558	bacterial-type flagellum-dependent cell motility
HT132_RS12465	COG1815	bacterial-type flagellum-dependent cell motility
HT132_RS12485	COG4974	Belongs to the 'phage' integrase family
HT132_RS12495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HT132_RS12500	COG0758	DNA mediated transformation
HT132_RS12505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HT132_RS12515	COG2257	FlhB HrpN YscU SpaS Family
HT132_RS12530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HT132_RS12555	COG1837	Belongs to the UPF0109 family
HT132_RS12565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HT132_RS12580	COG0552	protein localization to endoplasmic reticulum
HT132_RS12585	COG1196	nuclear chromosome segregation
HT132_RS12600	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS12605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HT132_RS12620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HT132_RS12625	COG1760	l-serine dehydratase
HT132_RS12630	COG1760	l-serine dehydratase
HT132_RS12635	COG1461	Dihydroxyacetone kinase
HT132_RS12640	COG1302	Protein conserved in bacteria
HT132_RS12655	COG1564	THIamine pyrophosphokinase
HT132_RS12660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HT132_RS12670	COG0515	serine threonine protein kinase
HT132_RS12670	COG2815	serine threonine protein kinase
HT132_RS12675	COG0631	protein serine/threonine phosphatase activity
HT132_RS12685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HT132_RS12685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HT132_RS12695	COG0242	peptide deformylase activity
HT132_RS12700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HT132_RS12705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HT132_RS12715	COG0194	GDP metabolic process
HT132_RS12725	COG1561	YicC-like family, N-terminal region
HT132_RS12730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HT132_RS12745	COG1648	precorrin-2 dehydrogenase activity
HT132_RS12750	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HT132_RS12755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HT132_RS12770	COG0306	phosphate transporter
HT132_RS12780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HT132_RS12785	COG0284	orotidine-5'-phosphate decarboxylase activity
HT132_RS12800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_RS12805	COG0505	Belongs to the CarA family
HT132_RS12810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HT132_RS12820	COG2233	PERMEase
HT132_RS12830	COG0564	pseudouridine synthase activity
HT132_RS12840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HT132_RS12845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HT132_RS12850	COG3599	regulation of cell shape
HT132_RS12855	COG2302	S4 RNA-binding domain
HT132_RS12860	COG0762	integral membrane protein
HT132_RS12870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HT132_RS12880	COG1873	PFAM PRC-barrel domain
HT132_RS12885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HT132_RS12890	COG1119	ATPase activity
HT132_RS12895	COG1191	sigma factor activity
HT132_RS12900	COG1191	sigma factor activity
HT132_RS12910	COG4412	M6 family metalloprotease domain protein
HT132_RS12910	COG1404	Belongs to the peptidase S8 family
HT132_RS12915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HT132_RS12920	COG0849	cell division
HT132_RS12925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HT132_RS12940	COG0772	Belongs to the SEDS family
HT132_RS12960	COG0768	penicillin binding
HT132_RS12970	COG4839	cell division protein FtsL
HT132_RS12990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HT132_RS13010	COG1399	metal-binding, possibly nucleic acid-binding protein
HT132_RS13020	COG3480	Lon protease (S16) C-terminal proteolytic domain
HT132_RS13025	COG1752	Esterase of the alpha-beta hydrolase superfamily
HT132_RS13030	COG3314	Sporulation integral membrane protein YlbJ
HT132_RS13040	COG0742	ribosomal rna small subunit methyltransferase
HT132_RS13050	COG3679	Belongs to the UPF0342 family
HT132_RS13065	COG2340	Cysteine-rich secretory protein family
HT132_RS13070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HT132_RS13080	COG3336	cytochrome c oxidase
HT132_RS13085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HT132_RS13090	COG1845	cytochrome c oxidase, subunit III
HT132_RS13095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HT132_RS13100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HT132_RS13100	COG2010	Cytochrome c
HT132_RS13115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HT132_RS13120	COG0772	Belongs to the SEDS family
HT132_RS13130	COG2066	Belongs to the glutaminase family
HT132_RS13135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HT132_RS13140	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HT132_RS13150	COG4896	Protein conserved in bacteria
HT132_RS13185	COG3227	Zinc metalloprotease (Elastase)
HT132_RS13195	COG0483	inositol monophosphate 1-phosphatase activity
HT132_RS13215	COG1982	Orn Lys Arg decarboxylase major
HT132_RS13230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS13235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_RS13240	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_RS13245	COG0022	dehydrogenase e1 component
HT132_RS13250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_RS13255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_RS13260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS13260	COG3321	synthase
HT132_RS13260	COG4221	oxidoreductase activity
HT132_RS13265	COG0300	oxidoreductase activity
HT132_RS13265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS13265	COG4221	oxidoreductase activity
HT132_RS13265	COG3321	synthase
HT132_RS13270	COG0300	oxidoreductase activity
HT132_RS13270	COG3321	synthase
HT132_RS13270	COG4221	oxidoreductase activity
HT132_RS13270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS13275	COG0300	oxidoreductase activity
HT132_RS13275	COG4221	oxidoreductase activity
HT132_RS13275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS13275	COG3321	synthase
HT132_RS13280	COG4221	oxidoreductase activity
HT132_RS13280	COG3321	synthase
HT132_RS13280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS13285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HT132_RS13285	COG3321	synthase
HT132_RS13285	COG0300	oxidoreductase activity
HT132_RS13285	COG4221	oxidoreductase activity
HT132_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS13290	COG4221	oxidoreductase activity
HT132_RS13290	COG3321	synthase
HT132_RS13290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS13300	COG0497	DNA recombination
HT132_RS13310	COG0242	peptide deformylase activity
HT132_RS13315	COG0561	phosphatase activity
HT132_RS13325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HT132_RS13335	COG0569	domain protein
HT132_RS13340	COG2105	PFAM AIG2 family protein
HT132_RS13340	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HT132_RS13345	COG3852	Histidine kinase
HT132_RS13350	COG2002	toxin-antitoxin pair type II binding
HT132_RS13355	COG1077	Cell shape determining protein MreB Mrl
HT132_RS13365	COG2309	aminopeptidase activity
HT132_RS13370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HT132_RS13375	COG0488	(ABC) transporter
HT132_RS13385	COG0681	Belongs to the peptidase S26 family
HT132_RS13390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_RS13390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HT132_RS13390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS13395	COG1105	Belongs to the carbohydrate kinase PfkB family
HT132_RS13400	COG1349	DNA-binding transcription factor activity
HT132_RS13405	COG0577	efflux transmembrane transporter activity
HT132_RS13410	COG1136	(ABC) transporter
HT132_RS13415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HT132_RS13425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HT132_RS13430	COG0314	molybdopterin synthase activity
HT132_RS13435	COG1763	Mo-molybdopterin cofactor biosynthetic process
HT132_RS13440	COG0303	'Molybdopterin
HT132_RS13445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_RS13465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS13470	COG0668	transmembrane transport
HT132_RS13490	COG0716	FMN binding
HT132_RS13500	COG0716	FMN binding
HT132_RS13505	COG0583	DNA-binding transcription factor activity
HT132_RS13510	COG0517	IMP dehydrogenase activity
HT132_RS13520	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HT132_RS13525	COG4703	Protein of unknown function (DUF1797)
HT132_RS13530	COG2200	EAL domain
HT132_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS13545	COG1408	metallophosphoesterase
HT132_RS13550	COG1376	ErfK ybiS ycfS ynhG family protein
HT132_RS13555	COG2814	Major facilitator Superfamily
HT132_RS13565	COG0835	chemotaxis
HT132_RS13565	COG0784	Response regulator, receiver
HT132_RS13575	COG0436	Aminotransferase
HT132_RS13580	COG4191	Histidine kinase
HT132_RS13585	COG0768	penicillin binding
HT132_RS13590	COG2340	Cysteine-rich secretory protein family
HT132_RS13595	COG2084	Dehydrogenase
HT132_RS13600	COG0840	transmembrane signaling receptor activity
HT132_RS13605	COG1533	DNA photolyase activity
HT132_RS13615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HT132_RS13620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS13625	COG2190	(PTS) system
HT132_RS13625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS13625	COG1263	PTS System
HT132_RS13630	COG3711	transcriptional antiterminator
HT132_RS13635	COG1609	Transcriptional regulator
HT132_RS13640	COG0006	proline dipeptidase activity
HT132_RS13645	COG2217	Heavy metal translocating P-type atpase
HT132_RS13650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS13655	COG2244	polysaccharide biosynthetic process
HT132_RS13660	COG3773	Cell wall hydrolase
HT132_RS13670	COG4873	Protein conserved in bacteria
HT132_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS13690	COG1733	regulation of RNA biosynthetic process
HT132_RS13695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HT132_RS13700	COG0602	queuosine metabolic process
HT132_RS13705	COG0720	synthase
HT132_RS13720	COG3949	Membrane
HT132_RS13725	COG0542	response to heat
HT132_RS13730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HT132_RS13735	COG1360	Flagellar Motor Protein
HT132_RS13740	COG1846	Transcriptional regulator
HT132_RS13745	COG3852	Histidine kinase
HT132_RS13775	COG0436	Aminotransferase
HT132_RS13780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HT132_RS13795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HT132_RS13800	COG5002	protein histidine kinase activity
HT132_RS13805	COG3594	Acyltransferase
HT132_RS13815	COG2323	membrane
HT132_RS13820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HT132_RS13845	COG1191	sigma factor activity
HT132_RS13850	COG0861	Integral membrane protein TerC family
HT132_RS13855	COG0586	Pfam SNARE associated Golgi protein
HT132_RS13860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HT132_RS13865	COG1793	dna ligase
HT132_RS13865	COG3285	dna ligase
HT132_RS13870	COG0726	polysaccharide deacetylase
HT132_RS13875	COG1846	Transcriptional regulator
HT132_RS13890	COG0789	Transcriptional regulator
HT132_RS13895	COG2239	Acts as a magnesium transporter
HT132_RS13905	COG3858	chitin binding
HT132_RS13905	COG1388	LysM domain
HT132_RS13910	COG4721	ABC-type cobalt transport system, permease component
HT132_RS13915	COG1122	ATPase activity
HT132_RS13920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HT132_RS13925	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS13930	COG1404	Belongs to the peptidase S8 family
HT132_RS13940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HT132_RS13945	COG2814	Major facilitator Superfamily
HT132_RS13955	COG0457	Tetratricopeptide repeat
HT132_RS13955	COG0463	Glycosyl transferase, family 2
HT132_RS13970	COG1764	response to oxidative stress
HT132_RS13975	COG1846	Transcriptional regulator
HT132_RS13980	COG1764	response to oxidative stress
HT132_RS13990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HT132_RS13995	COG0788	formyltetrahydrofolate deformylase activity
HT132_RS14000	COG2076	Multidrug Resistance protein
HT132_RS14005	COG2076	Multidrug Resistance protein
HT132_RS14010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_RS14015	COG1607	acyl-coa hydrolase
HT132_RS14020	COG1834	amidinotransferase
HT132_RS14025	COG2706	6-phosphogluconolactonase activity
HT132_RS14030	COG4608	Belongs to the ABC transporter superfamily
HT132_RS14035	COG0791	NLP P60 protein
HT132_RS14040	COG4948	Mandelate Racemase Muconate Lactonizing
HT132_RS14045	COG1619	proteins homologs of microcin C7 resistance protein MccF
HT132_RS14050	COG4166	transmembrane transport
HT132_RS14055	COG0444	Belongs to the ABC transporter superfamily
HT132_RS14060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_RS14065	COG0601	transmembrane transport
HT132_RS14070	COG2362	D-Aminopeptidase
HT132_RS14075	COG0477	Major facilitator Superfamily
HT132_RS14080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HT132_RS14090	COG0463	Glycosyl transferase, family 2
HT132_RS14095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HT132_RS14100	COG0346	lactoylglutathione lyase activity
HT132_RS14105	COG0531	amino acid
HT132_RS14110	COG1392	Phosphate transport regulator
HT132_RS14115	COG0306	phosphate transporter
HT132_RS14130	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS14130	COG5632	N-Acetylmuramoyl-L-alanine amidase
HT132_RS14170	COG3778	Protein conserved in bacteria
HT132_RS14175	COG3299	homolog of phage Mu protein gp47
HT132_RS14180	COG3628	GPW Gp25 family protein
HT132_RS14190	COG4193	domain, Protein
HT132_RS14195	COG1652	LysM domain
HT132_RS14200	COG3953	SLT domain
HT132_RS14200	COG5412	phage tail tape measure protein
HT132_RS14200	COG3953	SLT domain
HT132_RS14200	COG5412	phage tail tape measure protein
HT132_RS14200	COG5412	phage tail tape measure protein
HT132_RS14200	COG3953	SLT domain
HT132_RS14250	COG4653	Phage capsid family
HT132_RS14255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HT132_RS14260	COG5518	Phage portal protein
HT132_RS14265	COG1783	phage Terminase large subunit
HT132_RS14270	COG3728	DNA packaging
HT132_RS14270	COG5484	DNA packaging
HT132_RS14275	COG1595	DNA-templated transcription, initiation
HT132_RS14295	COG1484	DNA-dependent DNA replication
HT132_RS14300	COG1522	sequence-specific DNA binding
HT132_RS14310	COG1396	sequence-specific DNA binding
HT132_RS14315	COG2856	Zn peptidase
HT132_RS14320	COG3546	catalase activity
HT132_RS14325	COG4195	phage-related replication protein
HT132_RS14335	COG5632	N-Acetylmuramoyl-L-alanine amidase
HT132_RS14335	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS14335	COG1388	LysM domain
HT132_RS14345	COG0457	Tetratricopeptide repeat
HT132_RS14350	COG2318	DinB family
HT132_RS14355	COG0730	response to heat
HT132_RS14360	COG2721	sulfolactate sulfo-lyase activity
HT132_RS14365	COG0246	Mannitol dehydrogenase
HT132_RS14370	COG1609	Transcriptional regulator
HT132_RS14375	COG2211	Major facilitator Superfamily
HT132_RS14385	COG1252	NADH dehydrogenase
HT132_RS14395	COG4297	protein containing double-stranded beta helix domain
HT132_RS14400	COG0697	spore germination
HT132_RS14405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HT132_RS14410	COG0390	transport system, permease component
HT132_RS14415	COG1587	Uroporphyrinogen-III synthase
HT132_RS14425	COG1819	glycosyl
HT132_RS14430	COG2124	cytochrome p450
HT132_RS14435	COG2427	Protein of unknown function (DUF1641)
HT132_RS14440	COG3383	formate dehydrogenase (NAD+) activity
HT132_RS14450	COG2205	protein histidine kinase activity
HT132_RS14465	COG1285	pathogenesis
HT132_RS14495	COG1447	Phosphotransferase system cellobiose-specific component IIA
HT132_RS14500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS14500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HT132_RS14505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HT132_RS14510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HT132_RS14515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HT132_RS14525	COG1846	Transcriptional regulator
HT132_RS14530	COG0477	Major facilitator Superfamily
HT132_RS14535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HT132_RS14540	COG2367	Beta-lactamase
HT132_RS14545	COG0346	lactoylglutathione lyase activity
HT132_RS14555	COG0135	phosphoribosylanthranilate isomerase activity
HT132_RS14600	COG5444	nuclease activity
HT132_RS14630	COG0626	cystathionine gamma-synthase activity
HT132_RS14635	COG0626	cystathionine gamma-synthase activity
HT132_RS14640	COG2382	esterase
HT132_RS14650	COG2153	protein acetylation
HT132_RS14660	COG1131	(ABC) transporter
HT132_RS14680	COG0210	DNA helicase
HT132_RS14735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HT132_RS14740	COG0351	phosphomethylpyrimidine kinase
HT132_RS14745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HT132_RS14755	COG2104	thiamine diphosphate biosynthetic process
HT132_RS14760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_RS14765	COG0352	thiamine-phosphate diphosphorylase activity
HT132_RS14770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HT132_RS14775	COG0569	domain protein
HT132_RS14775	COG0475	glutathione-regulated potassium exporter activity
HT132_RS14785	COG0564	pseudouridine synthase activity
HT132_RS14790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HT132_RS14795	COG2357	RelA SpoT domain protein
HT132_RS14805	COG4116	CYTH
HT132_RS14810	COG0741	lytic transglycosylase activity
HT132_RS14815	COG2346	COG2346, Truncated hemoglobins
HT132_RS14830	COG1164	Oligoendopeptidase f
HT132_RS14835	COG4469	Competence protein
HT132_RS14840	COG4862	establishment of competence for transformation
HT132_RS14850	COG0861	Integral membrane protein TerC family
HT132_RS14855	COG1393	Belongs to the ArsC family
HT132_RS14860	COG0456	acetyltransferase
HT132_RS14870	COG4608	Belongs to the ABC transporter superfamily
HT132_RS14875	COG0444	Belongs to the ABC transporter superfamily
HT132_RS14880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_RS14885	COG0601	transmembrane transport
HT132_RS14890	COG4166	transmembrane transport
HT132_RS14895	COG0180	Tryptophanyl-tRNA synthetase
HT132_RS14905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_RS14910	COG0601	transmembrane transport
HT132_RS14920	COG4608	Belongs to the ABC transporter superfamily
HT132_RS14925	COG0444	Belongs to the ABC transporter superfamily
HT132_RS14930	COG5504	Zn-dependent protease
HT132_RS14935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_RS14940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_RS14955	COG1744	ABC transporter substrate-binding protein PnrA-like
HT132_RS14965	COG2267	carboxylic ester hydrolase activity
HT132_RS14980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HT132_RS14985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_RS14990	COG0505	Belongs to the CarA family
HT132_RS14995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HT132_RS15005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HT132_RS15015	COG2271	Major facilitator Superfamily
HT132_RS15020	COG0277	FAD linked oxidase domain protein
HT132_RS15030	COG2151	metal-sulfur cluster biosynthetic enzyme
HT132_RS15035	COG1073	alpha beta
HT132_RS15040	COG0561	phosphatase activity
HT132_RS15060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS15065	COG1307	EDD domain protein, DegV family
HT132_RS15075	COG2124	cytochrome p450
HT132_RS15080	COG0840	transmembrane signaling receptor activity
HT132_RS15090	COG2996	Protein conserved in bacteria
HT132_RS15100	COG0646	methionine synthase
HT132_RS15100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HT132_RS15105	COG2153	protein acetylation
HT132_RS15110	COG1357	PFAM Pentapeptide repeats (8 copies)
HT132_RS15115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS15120	COG1279	arginine transmembrane transporter activity
HT132_RS15125	COG2318	DinB family
HT132_RS15130	COG0673	inositol 2-dehydrogenase activity
HT132_RS15135	COG1609	Transcriptional regulator
HT132_RS15140	COG2207	Transcriptional regulator
HT132_RS15140	COG1917	Cupin 2, conserved barrel domain protein
HT132_RS15145	COG0534	Mate efflux family protein
HT132_RS15150	COG1562	ergosterol biosynthetic process
HT132_RS15155	COG0367	asparagine synthase
HT132_RS15175	COG0179	Fumarylacetoacetate (FAA) hydrolase
HT132_RS15215	COG1403	HNH endonuclease
HT132_RS15220	COG0419	ATPase involved in DNA repair
HT132_RS15225	COG0420	3'-5' exonuclease activity
HT132_RS15240	COG2323	membrane
HT132_RS15245	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HT132_RS15255	COG2814	Major facilitator Superfamily
HT132_RS15260	COG3180	Ammonia monooxygenase
HT132_RS15265	COG1846	Transcriptional regulator
HT132_RS15270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HT132_RS15275	COG0681	Belongs to the peptidase S26 family
HT132_RS15280	COG0398	Pfam SNARE associated Golgi protein
HT132_RS15295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_RS15320	COG5646	InterPro IPR014922
HT132_RS15330	COG4903	ComK protein
HT132_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS15345	COG0723	plastoquinol--plastocyanin reductase activity
HT132_RS15345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HT132_RS15350	COG0840	transmembrane signaling receptor activity
HT132_RS15355	COG1268	BioY protein
HT132_RS15360	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS15365	COG0183	Belongs to the thiolase family
HT132_RS15370	COG0406	alpha-ribazole phosphatase activity
HT132_RS15375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HT132_RS15380	COG1404	Belongs to the peptidase S8 family
HT132_RS15385	COG0501	Belongs to the peptidase M48B family
HT132_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS15400	COG0702	epimerase
HT132_RS15405	COG0095	Lipoate-protein ligase
HT132_RS15410	COG1234	tRNA 3'-trailer cleavage
HT132_RS15420	COG1301	dicarboxylic acid transport
HT132_RS15425	COG1363	Peptidase, m42
HT132_RS15435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HT132_RS15440	COG1511	domain protein
HT132_RS15445	COG1309	transcriptional regulator
HT132_RS15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HT132_RS15470	COG2329	Antibiotic biosynthesis monooxygenase
HT132_RS15475	COG3069	C4-dicarboxylate transmembrane transporter activity
HT132_RS15480	COG1473	amidohydrolase
HT132_RS15490	COG4473	ABC transporter
HT132_RS15495	COG1131	(ABC) transporter
HT132_RS15500	COG0537	adenosine 5'-monophosphoramidase activity
HT132_RS15505	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HT132_RS15520	COG4980	gas vesicle protein
HT132_RS15555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HT132_RS15570	COG4717	serine-type aminopeptidase activity
HT132_RS15575	COG0420	3'-5' exonuclease activity
HT132_RS15580	COG1668	transmembrane transport
HT132_RS15585	COG4152	abc transporter atp-binding protein
HT132_RS15595	COG1024	Enoyl-CoA hydratase
HT132_RS15605	COG0490	domain, Protein
HT132_RS15610	COG0475	glutathione-regulated potassium exporter activity
HT132_RS15620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HT132_RS15625	COG0561	phosphatase activity
HT132_RS15630	COG4335	DNA alkylation repair
HT132_RS15645	COG0189	ligase activity
HT132_RS15650	COG0189	ligase activity
HT132_RS15665	COG0702	epimerase
HT132_RS15670	COG1132	(ABC) transporter
HT132_RS15675	COG1132	(ABC) transporter
HT132_RS15680	COG0589	response to stress
HT132_RS15690	COG3226	Transcriptional regulator
HT132_RS15695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_RS15700	COG0726	polysaccharide deacetylase
HT132_RS15705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HT132_RS15710	COG0668	transmembrane transport
HT132_RS15720	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_RS15725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HT132_RS15730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HT132_RS15735	COG1253	flavin adenine dinucleotide binding
HT132_RS15740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_RS15745	COG0436	Aminotransferase
HT132_RS15750	COG0789	Transcriptional regulator
HT132_RS15755	COG1253	flavin adenine dinucleotide binding
HT132_RS15760	COG0204	Acyl-transferase
HT132_RS15765	COG1595	DNA-templated transcription, initiation
HT132_RS15780	COG0733	neurotransmitter:sodium symporter activity
HT132_RS15785	COG0531	amino acid
HT132_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS15795	COG0372	Belongs to the citrate synthase family
HT132_RS15800	COG0583	DNA-binding transcription factor activity
HT132_RS15805	COG1388	LysM domain
HT132_RS15805	COG0791	NLP P60 protein
HT132_RS15810	COG1785	Belongs to the alkaline phosphatase family
HT132_RS15815	COG2719	SpoVR family
HT132_RS15820	COG0668	transmembrane transport
HT132_RS15825	COG1959	2 iron, 2 sulfur cluster binding
HT132_RS15830	COG0791	NLP P60 protein
HT132_RS15830	COG1388	LysM domain
HT132_RS15845	COG0431	NADPH-dependent FMN reductase
HT132_RS15850	COG2197	response regulator
HT132_RS15855	COG4585	Histidine kinase
HT132_RS15855	COG2203	Gaf domain
HT132_RS15860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HT132_RS15865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HT132_RS15875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HT132_RS15880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HT132_RS15890	COG3153	acetyltransferase
HT132_RS15890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HT132_RS15895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HT132_RS15900	COG0517	IMP dehydrogenase activity
HT132_RS15910	COG0564	pseudouridine synthase activity
HT132_RS15915	COG3764	Sortase (surface protein transpeptidase)
HT132_RS15920	COG1525	nuclease
HT132_RS15920	COG0737	Belongs to the 5'-nucleotidase family
HT132_RS15920	COG4085	toxin activity
HT132_RS15925	COG5577	PFAM Coat F domain
HT132_RS15945	COG1823	symporter activity
HT132_RS15950	COG3706	GGDEF domain
HT132_RS15955	COG1464	Belongs to the NlpA lipoprotein family
HT132_RS15960	COG1278	Cold shock
HT132_RS15965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_RS15970	COG1131	(ABC) transporter
HT132_RS15975	COG1131	(ABC) transporter
HT132_RS15980	COG1725	Transcriptional regulator
HT132_RS15995	COG0655	NAD(P)H dehydrogenase (quinone) activity
HT132_RS16000	COG2814	Major facilitator Superfamily
HT132_RS16005	COG1566	PFAM secretion protein HlyD family protein
HT132_RS16010	COG1846	Transcriptional regulator
HT132_RS16020	COG2766	serine protein kinase
HT132_RS16025	COG1664	Polymer-forming cytoskeletal
HT132_RS16030	COG1664	Polymer-forming cytoskeletal
HT132_RS16035	COG0789	Transcriptional regulator
HT132_RS16040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HT132_RS16050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HT132_RS16055	COG3382	B3 4 domain protein
HT132_RS16065	COG1476	TRANSCRIPTIONal
HT132_RS16085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HT132_RS16090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HT132_RS16095	COG1116	anion transmembrane transporter activity
HT132_RS16105	COG0753	catalase activity
HT132_RS16110	COG4608	Belongs to the ABC transporter superfamily
HT132_RS16115	COG0444	Belongs to the ABC transporter superfamily
HT132_RS16120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HT132_RS16140	COG0277	FAD linked oxidase domain protein
HT132_RS16150	COG3340	Belongs to the peptidase S51 family
HT132_RS16265	COG0735	belongs to the Fur family
HT132_RS16270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HT132_RS16280	COG4129	membrane
HT132_RS16285	COG1132	(ABC) transporter
HT132_RS16305	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS16315	COG1194	a g-specific adenine glycosylase
HT132_RS16320	COG1988	membrane-bound metal-dependent
HT132_RS16325	COG4485	Bacterial membrane protein, YfhO
HT132_RS16335	COG0596	Alpha beta hydrolase
HT132_RS16340	COG5658	integral membrane protein
HT132_RS16345	COG3103	Sh3 type 3 domain protein
HT132_RS16360	COG3591	Belongs to the peptidase S1B family
HT132_RS16370	COG2814	Major facilitator Superfamily
HT132_RS16385	COG1090	epimerase
HT132_RS16400	COG0778	Nitroreductase
HT132_RS16405	COG0384	phenazine biosynthesis protein PhzF
HT132_RS16410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HT132_RS16410	COG0392	lysyltransferase activity
HT132_RS16415	COG1846	Transcriptional regulator
HT132_RS16420	COG2814	Major facilitator Superfamily
HT132_RS16425	COG2318	DinB family
HT132_RS16430	COG2732	(Barnase) inhibitor
HT132_RS16435	COG3848	Pyruvate phosphate dikinase
HT132_RS16435	COG0574	Belongs to the PEP-utilizing enzyme family
HT132_RS16440	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HT132_RS16445	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_RS16450	COG1695	Transcriptional regulator
HT132_RS16460	COG2514	catechol 2,3-dioxygenase activity
HT132_RS16465	COG2259	Doxx family
HT132_RS16470	COG1132	(ABC) transporter
HT132_RS16475	COG1132	(ABC) transporter
HT132_RS16480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS16480	COG1263	PTS System
HT132_RS16485	COG1737	Transcriptional regulator
HT132_RS16490	COG1486	melibiose metabolic process
HT132_RS16500	COG3284	Transcriptional regulator
HT132_RS16505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HT132_RS16510	COG0508	dehydrogenase complex catalyzes the overall conversion of
HT132_RS16515	COG0022	dehydrogenase e1 component
HT132_RS16520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HT132_RS16525	COG4637	Psort location Cytoplasmic, score
HT132_RS16530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HT132_RS16540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HT132_RS16545	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HT132_RS16550	COG0598	Magnesium transport protein CorA
HT132_RS16560	COG2084	Dehydrogenase
HT132_RS16565	COG0726	polysaccharide deacetylase
HT132_RS16575	COG0535	radical SAM domain protein
HT132_RS16580	COG0668	transmembrane transport
HT132_RS16590	COG0387	Pfam Sodium calcium exchanger
HT132_RS16595	COG0477	Major facilitator Superfamily
HT132_RS16605	COG1295	ribonuclease BN
HT132_RS16610	COG4980	gas vesicle protein
HT132_RS16615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HT132_RS16625	COG2814	Major facilitator Superfamily
HT132_RS16640	COG1609	Transcriptional regulator
HT132_RS16645	COG0693	protein deglycase activity
HT132_RS16650	COG0737	Belongs to the 5'-nucleotidase family
HT132_RS16665	COG0778	Nitroreductase
HT132_RS16670	COG2188	Transcriptional regulator
HT132_RS16675	COG0366	Alpha amylase catalytic
HT132_RS16680	COG1263	PTS System
HT132_RS16680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS16695	COG0071	Belongs to the small heat shock protein (HSP20) family
HT132_RS16705	COG1368	sulfuric ester hydrolase activity
HT132_RS16715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS16715	COG1263	PTS System
HT132_RS16720	COG0024	Methionine aminopeptidase
HT132_RS16740	COG2258	MOSC domain
HT132_RS16750	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HT132_RS16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS16760	COG2851	Citrate transporter
HT132_RS16765	COG3181	Tripartite tricarboxylate transporter family receptor
HT132_RS16770	COG4565	transcriptional regulatory protein
HT132_RS16775	COG3290	protein histidine kinase activity
HT132_RS16780	COG3764	Sortase (surface protein transpeptidase)
HT132_RS16790	COG3279	Response regulator of the LytR AlgR family
HT132_RS16795	COG2972	Histidine kinase
HT132_RS16795	COG0745	RESPONSE REGULATOR receiver
HT132_RS16815	COG0471	metal ion transport
HT132_RS16820	COG3866	Pectate lyase
HT132_RS16835	COG2130	NADP-dependent
HT132_RS16845	COG0513	Belongs to the DEAD box helicase family
HT132_RS16850	COG0488	(ABC) transporter
HT132_RS16855	COG2814	Major facilitator Superfamily
HT132_RS16860	COG0789	Transcriptional regulator
HT132_RS16865	COG0488	(ABC) transporter
HT132_RS16870	COG0457	Tetratricopeptide repeat
HT132_RS16870	COG0463	Glycosyl transferase, family 2
HT132_RS16875	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS16880	COG0840	transmembrane signaling receptor activity
HT132_RS16885	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS16890	COG0531	amino acid
HT132_RS16895	COG2223	nitrite transmembrane transporter activity
HT132_RS16900	COG1442	glycosyl transferase family 8
HT132_RS16905	COG1216	Glycosyl transferase, family 2
HT132_RS16910	COG1442	glycosyl transferase family 8
HT132_RS16915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HT132_RS16920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HT132_RS16925	COG1368	sulfuric ester hydrolase activity
HT132_RS16935	COG1131	(ABC) transporter
HT132_RS16950	COG2124	cytochrome p450
HT132_RS16950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HT132_RS16960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HT132_RS16965	COG1846	Transcriptional regulator
HT132_RS16970	COG0670	Belongs to the BI1 family
HT132_RS16975	COG0196	riboflavin kinase activity
HT132_RS16980	COG5583	Uncharacterized small protein (DUF2292)
HT132_RS16990	COG4208	sulfate ABC transporter
HT132_RS16995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HT132_RS17000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HT132_RS17005	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS17010	COG0346	lactoylglutathione lyase activity
HT132_RS17015	COG2329	Antibiotic biosynthesis monooxygenase
HT132_RS17020	COG2323	membrane
HT132_RS17030	COG0454	-acetyltransferase
HT132_RS17035	COG3546	catalase activity
HT132_RS17065	COG5444	nuclease activity
HT132_RS17125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HT132_RS17130	COG1597	lipid kinase activity
HT132_RS17140	COG1309	transcriptional regulator
HT132_RS17160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_RS17165	COG1285	pathogenesis
HT132_RS17170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HT132_RS17175	COG4851	CamS sex pheromone cAM373 precursor
HT132_RS17185	COG0210	DNA helicase
HT132_RS17195	COG0069	glutamate synthase activity
HT132_RS17200	COG4496	protein, YerC YecD
HT132_RS17205	COG1470	cell adhesion involved in biofilm formation
HT132_RS17210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HT132_RS17220	COG0151	Belongs to the GarS family
HT132_RS17225	COG0138	bifunctional purine biosynthesis protein purh
HT132_RS17230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HT132_RS17240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HT132_RS17255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HT132_RS17260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HT132_RS17265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HT132_RS17270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HT132_RS17275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HT132_RS17295	COG3064	Membrane
HT132_RS17300	COG2252	PERMEase
HT132_RS17315	COG2211	Major facilitator Superfamily
HT132_RS17335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HT132_RS17345	COG1305	Transglutaminase-like
HT132_RS17350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HT132_RS17355	COG0714	Associated with various cellular activities
HT132_RS17360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_RS17365	COG1113	amino acid transport
HT132_RS17370	COG2132	Multicopper oxidase
HT132_RS17385	COG0823	Involved in the tonB-independent uptake of proteins
HT132_RS17390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HT132_RS17395	COG1063	alcohol dehydrogenase
HT132_RS17400	COG1595	DNA-templated transcription, initiation
HT132_RS17410	COG2755	lipolytic protein G-D-S-L family
HT132_RS17410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HT132_RS17415	COG4260	virion core protein, lumpy skin disease virus
HT132_RS17420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HT132_RS17425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HT132_RS17430	COG1842	Phage shock protein A
HT132_RS17440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HT132_RS17445	COG2211	Major facilitator Superfamily
HT132_RS17450	COG1063	alcohol dehydrogenase
HT132_RS17455	COG0457	Tetratricopeptide repeat
HT132_RS17475	COG1266	CAAX protease self-immunity
HT132_RS17485	COG0805	protein transport
HT132_RS17490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HT132_RS17505	COG0488	(ABC) transporter
HT132_RS17510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HT132_RS17515	COG0456	acetyltransferase
HT132_RS17520	COG1214	PFAM Peptidase M22, glycoprotease
HT132_RS17525	COG0802	atpase or kinase
HT132_RS17530	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HT132_RS17570	COG2814	Major facilitator Superfamily
HT132_RS17575	COG0604	alcohol dehydrogenase
HT132_RS17580	COG3832	glyoxalase III activity
HT132_RS17590	COG0531	amino acid
HT132_RS17595	COG1309	transcriptional regulator
HT132_RS17600	COG2076	Multidrug Resistance protein
HT132_RS17605	COG2076	Multidrug Resistance protein
HT132_RS17610	COG2807	transmembrane transport
HT132_RS17615	COG2186	Transcriptional regulator
HT132_RS17620	COG2188	Transcriptional regulator
HT132_RS17625	COG2814	Major facilitator Superfamily
HT132_RS17630	COG1388	LysM domain
HT132_RS17640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_RS17655	COG1819	glycosyl
HT132_RS17660	COG1802	Transcriptional regulator
HT132_RS17665	COG0473	3-isopropylmalate dehydrogenase activity
HT132_RS17670	COG2226	methyltransferase
HT132_RS17680	COG0697	spore germination
HT132_RS17685	COG0789	Transcriptional regulator
HT132_RS17685	COG4978	Transcriptional regulator
HT132_RS17690	COG0456	acetyltransferase
HT132_RS17695	COG0730	response to heat
HT132_RS17705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HT132_RS17710	COG2814	Major facilitator Superfamily
HT132_RS17720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HT132_RS17725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_RS17735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HT132_RS17740	COG2409	Drug exporters of the RND superfamily
HT132_RS17745	COG2197	response regulator
HT132_RS17750	COG4585	Histidine kinase
HT132_RS17770	COG0738	Major facilitator superfamily
HT132_RS17780	COG5577	PFAM Coat F domain
HT132_RS17785	COG1063	alcohol dehydrogenase
HT132_RS17795	COG5577	PFAM Coat F domain
HT132_RS17800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS17805	COG0697	spore germination
HT132_RS17810	COG1309	transcriptional regulator
HT132_RS17815	COG2814	Major facilitator Superfamily
HT132_RS17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS17840	COG0789	Transcriptional regulator
HT132_RS17845	COG1064	alcohol dehydrogenase
HT132_RS17860	COG0351	phosphomethylpyrimidine kinase
HT132_RS17920	COG0477	Major facilitator Superfamily
HT132_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS17935	COG1917	Cupin 2, conserved barrel domain protein
HT132_RS17935	COG2207	Transcriptional regulator
HT132_RS17940	COG1473	amidohydrolase
HT132_RS17945	COG0814	amino acid
HT132_RS17950	COG0251	oxidation-reduction process
HT132_RS17955	COG1802	Transcriptional regulator
HT132_RS17960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HT132_RS17970	COG3621	Patatin-like phospholipase
HT132_RS17985	COG1794	racemase activity, acting on amino acids and derivatives
HT132_RS17990	COG0730	response to heat
HT132_RS17995	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_RS18000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HT132_RS18000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_RS18005	COG0425	Belongs to the sulfur carrier protein TusA family
HT132_RS18005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HT132_RS18015	COG2210	Belongs to the sulfur carrier protein TusA family
HT132_RS18020	COG1937	Protein conserved in bacteria
HT132_RS18025	COG1329	Transcriptional regulator
HT132_RS18030	COG1278	Cold shock
HT132_RS18040	COG2910	NAD(P)H-binding
HT132_RS18045	COG1959	2 iron, 2 sulfur cluster binding
HT132_RS18060	COG2030	dehydratase
HT132_RS18070	COG0477	Major facilitator Superfamily
HT132_RS18075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HT132_RS18095	COG0457	Tetratricopeptide repeat
HT132_RS18100	COG2249	NAD(P)H dehydrogenase (quinone) activity
HT132_RS18105	COG0457	Tetratricopeptide repeat
HT132_RS18155	COG2183	response to ionizing radiation
HT132_RS18160	COG2208	phosphoserine phosphatase activity
HT132_RS18165	COG1191	sigma factor activity
HT132_RS18175	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS18180	COG2208	phosphoserine phosphatase activity
HT132_RS18185	COG2172	sigma factor antagonist activity
HT132_RS18190	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS18195	COG1366	Belongs to the anti-sigma-factor antagonist family
HT132_RS18200	COG2337	Toxic component of a toxin-antitoxin (TA) module
HT132_RS18205	COG0864	Transcriptional regulator
HT132_RS18210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HT132_RS18215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HT132_RS18225	COG0705	Rhomboid family
HT132_RS18230	COG3428	Bacterial PH domain
HT132_RS18235	COG3402	PFAM membrane-flanked domain
HT132_RS18240	COG0513	Belongs to the DEAD box helicase family
HT132_RS18245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HT132_RS18255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HT132_RS18260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HT132_RS18275	COG1960	acyl-CoA dehydrogenase activity
HT132_RS18285	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HT132_RS18290	COG1131	(ABC) transporter
HT132_RS18295	COG0628	permease
HT132_RS18300	COG1301	dicarboxylic acid transport
HT132_RS18305	COG4565	transcriptional regulatory protein
HT132_RS18310	COG3290	protein histidine kinase activity
HT132_RS18315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HT132_RS18320	COG3546	catalase activity
HT132_RS18325	COG2329	Antibiotic biosynthesis monooxygenase
HT132_RS18330	COG0662	Cupin 2, conserved barrel domain protein
HT132_RS18335	COG3729	General stress protein
HT132_RS18340	COG2217	Heavy metal translocating P-type atpase
HT132_RS18345	COG2076	Multidrug Resistance protein
HT132_RS18355	COG4876	unkown
HT132_RS18365	COG1914	H( )-stimulated, divalent metal cation uptake system
HT132_RS18395	COG0028	Belongs to the TPP enzyme family
HT132_RS18400	COG0494	nUDIX hydrolase
HT132_RS18405	COG0531	amino acid
HT132_RS18415	COG1215	transferase activity, transferring glycosyl groups
HT132_RS18420	COG5298	Protein conserved in bacteria
HT132_RS18425	COG3706	GGDEF domain
HT132_RS18430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HT132_RS18435	COG0551	DNA topoisomerase type I activity
HT132_RS18435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HT132_RS18440	COG1522	sequence-specific DNA binding
HT132_RS18445	COG2814	Major facilitator Superfamily
HT132_RS18455	COG3871	stress protein (general stress protein 26)
HT132_RS18460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_RS18465	COG1917	Cupin 2, conserved barrel domain protein
HT132_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS18475	COG0318	PFAM AMP-dependent synthetase and ligase
HT132_RS18480	COG3711	transcriptional antiterminator
HT132_RS18485	COG4989	oxidoreductase activity
HT132_RS18490	COG0768	penicillin binding
HT132_RS18495	COG2329	Antibiotic biosynthesis monooxygenase
HT132_RS18505	COG2755	lipolytic protein G-D-S-L family
HT132_RS18510	COG1414	Transcriptional regulator
HT132_RS18515	COG1984	allophanate hydrolase subunit 2
HT132_RS18520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HT132_RS18530	COG1914	H( )-stimulated, divalent metal cation uptake system
HT132_RS18540	COG0561	phosphatase activity
HT132_RS18550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HT132_RS18560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HT132_RS18565	COG2213	PTS system mannitol-specific
HT132_RS18575	COG1349	DNA-binding transcription factor activity
HT132_RS18580	COG1276	copper resistance
HT132_RS18580	COG2372	response to copper ion
HT132_RS18585	COG4549	nuclear export factor GLE1
HT132_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS18595	COG4975	Glucose uptake
HT132_RS18600	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS18605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HT132_RS18610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HT132_RS18615	COG0640	Transcriptional regulator
HT132_RS18620	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HT132_RS18625	COG0778	Nitroreductase
HT132_RS18630	COG1309	transcriptional regulator
HT132_RS18635	COG2814	Major facilitator Superfamily
HT132_RS18640	COG4607	ABC-type enterochelin transport system periplasmic component
HT132_RS18645	COG4604	ABC transporter, ATP-binding protein
HT132_RS18650	COG4605	iron ion homeostasis
HT132_RS18655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS18660	COG0527	aspartate kinase activity
HT132_RS18675	COG0457	Tetratricopeptide repeat
HT132_RS18680	COG5002	protein histidine kinase activity
HT132_RS18680	COG3850	Histidine kinase
HT132_RS18685	COG0745	RESPONSE REGULATOR receiver
HT132_RS18690	COG0577	efflux transmembrane transporter activity
HT132_RS18695	COG1136	(ABC) transporter
HT132_RS18700	COG2079	MmgE PrpD family protein
HT132_RS18705	COG1473	amidohydrolase
HT132_RS18710	COG1126	abc transporter atp-binding protein
HT132_RS18715	COG0765	amino acid transport
HT132_RS18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS18725	COG0456	acetyltransferase
HT132_RS18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS18735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HT132_RS18745	COG0697	spore germination
HT132_RS18755	COG5434	Belongs to the glycosyl hydrolase 28 family
HT132_RS18760	COG3104	oligopeptide transport
HT132_RS18775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HT132_RS18780	COG0163	prenyltransferase activity
HT132_RS18785	COG0583	DNA-binding transcription factor activity
HT132_RS18790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HT132_RS18795	COG0765	amino acid transport
HT132_RS18800	COG1126	abc transporter atp-binding protein
HT132_RS18805	COG2364	Membrane
HT132_RS18820	COG0697	spore germination
HT132_RS18835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HT132_RS18840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS18845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS18850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HT132_RS18855	COG1733	regulation of RNA biosynthetic process
HT132_RS18860	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HT132_RS18865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HT132_RS18870	COG3209	COG3209 Rhs family protein
HT132_RS18880	COG2723	6-phospho-beta-galactosidase activity
HT132_RS18890	COG1714	RDD family
HT132_RS18895	COG1063	alcohol dehydrogenase
HT132_RS18900	COG0523	cobalamin synthesis protein
HT132_RS18905	COG2223	nitrite transmembrane transporter activity
HT132_RS18910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HT132_RS18915	COG0243	molybdopterin cofactor binding
HT132_RS18920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HT132_RS18925	COG2146	nitrite reductase [NAD(P)H] activity
HT132_RS18930	COG1587	Uroporphyrinogen-III synthase
HT132_RS18930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HT132_RS18940	COG2508	Transcriptional regulator
HT132_RS18945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HT132_RS18950	COG1012	belongs to the aldehyde dehydrogenase family
HT132_RS18955	COG0506	proline dehydrogenase activity
HT132_RS18960	COG3541	Predicted nucleotidyltransferase
HT132_RS18965	COG3458	cephalosporin-C deacetylase activity
HT132_RS18970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HT132_RS18975	COG2271	Major facilitator Superfamily
HT132_RS18985	COG1660	Displays ATPase and GTPase activities
HT132_RS19000	COG3665	Urea carboxylase-associated protein
HT132_RS19005	COG1113	amino acid transport
HT132_RS19010	COG3403	YqcI/YcgG family
HT132_RS19015	COG1280	lysine exporter protein (LysE YggA)
HT132_RS19020	COG1846	Transcriptional regulator
HT132_RS19025	COG2814	Major facilitator Superfamily
HT132_RS19035	COG0366	Alpha amylase catalytic
HT132_RS19045	COG1288	antiporter activity
HT132_RS19050	COG1473	amidohydrolase
HT132_RS19055	COG2113	Glycine betaine
HT132_RS19060	COG4176	ABC-type proline glycine betaine transport system permease component
HT132_RS19065	COG4175	Glycine betaine
HT132_RS19065	COG0517	IMP dehydrogenase activity
HT132_RS19070	COG0477	Major facilitator Superfamily
HT132_RS19075	COG3853	Toxic anion resistance protein (TelA)
HT132_RS19085	COG0861	Integral membrane protein TerC family
HT132_RS19090	COG2310	stress, protein
HT132_RS19095	COG2310	stress, protein
HT132_RS19100	COG2310	stress, protein
HT132_RS19105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HT132_RS19110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HT132_RS19115	COG1121	(ABC) transporter
HT132_RS19120	COG0803	Belongs to the bacterial solute-binding protein 9 family
HT132_RS19125	COG0366	Alpha amylase catalytic
HT132_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
HT132_RS19140	COG0457	Tetratricopeptide repeat
HT132_RS19145	COG1876	peptidase activity
HT132_RS19150	COG1595	DNA-templated transcription, initiation
HT132_RS19155	COG1595	DNA-templated transcription, initiation
HT132_RS19165	COG0667	Aldo Keto reductase
HT132_RS19170	COG1405	negative regulation of cell septum assembly
HT132_RS19170	COG3012	SEC-C Motif Domain Protein
HT132_RS19175	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HT132_RS19180	COG0252	asparaginase activity
HT132_RS19185	COG1309	transcriptional regulator
HT132_RS19190	COG0477	Major facilitator Superfamily
HT132_RS19195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HT132_RS19205	COG0805	protein transport
HT132_RS19210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HT132_RS19215	COG3540	Alkaline phosphatase
HT132_RS19220	COG3773	Cell wall hydrolase
HT132_RS19235	COG3173	Aminoglycoside phosphotransferase
HT132_RS19240	COG0784	Response regulator, receiver
HT132_RS19245	COG4191	Histidine kinase
HT132_RS19250	COG2066	Belongs to the glutaminase family
HT132_RS19255	COG1115	amino acid carrier protein
HT132_RS19260	COG2040	homocysteine
HT132_RS19265	COG0833	amino acid
HT132_RS19270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HT132_RS19275	COG1301	dicarboxylic acid transport
HT132_RS19290	COG0688	phosphatidylethanolamine metabolic process
HT132_RS19295	COG0586	Pfam SNARE associated Golgi protein
HT132_RS19300	COG1183	phosphatidylcholine synthase activity
HT132_RS19310	COG0371	Dehydrogenase
HT132_RS19325	COG3409	Peptidoglycan-binding domain 1 protein
HT132_RS19335	COG2368	4-hydroxyphenylacetate
HT132_RS19345	COG2271	Major facilitator Superfamily
HT132_RS19350	COG0584	glycerophosphoryl diester phosphodiesterase
HT132_RS19370	COG0531	amino acid
HT132_RS19410	COG1131	(ABC) transporter
HT132_RS19415	COG2197	response regulator
HT132_RS19420	COG4585	Histidine kinase
HT132_RS19425	COG1011	Hydrolase
HT132_RS19430	COG1113	amino acid transport
HT132_RS19435	COG1846	Transcriptional regulator
HT132_RS19440	COG1380	Effector of murein hydrolase LrgA
HT132_RS19445	COG1346	cytolysis
HT132_RS19500	COG4856	YbbR-like protein
HT132_RS19505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HT132_RS19510	COG5662	AntiSigma factor
HT132_RS19515	COG1595	DNA-templated transcription, initiation
HT132_RS19550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HT132_RS19560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HT132_RS19560	COG1263	PTS System
HT132_RS19565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HT132_RS19570	COG1472	Belongs to the glycosyl hydrolase 3 family
HT132_RS19575	COG3876	Protein conserved in bacteria
HT132_RS19580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_RS19580	COG2207	Transcriptional regulator
HT132_RS19585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HT132_RS19590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS19595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HT132_RS19600	COG2819	hydrolase of the alpha beta superfamily
HT132_RS19605	COG0385	Bile acid
HT132_RS19610	COG0659	secondary active sulfate transmembrane transporter activity
HT132_RS19625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HT132_RS19630	COG0738	Major facilitator superfamily