locus-tag	class	description
DOU34_RS00085	COG0667	Aldo Keto reductase
DOU34_RS00095	COG1595	DNA-templated transcription, initiation
DOU34_RS00100	COG1595	DNA-templated transcription, initiation
DOU34_RS00105	COG1876	peptidase activity
DOU34_RS00110	COG0457	Tetratricopeptide repeat
DOU34_RS00120	COG0366	Alpha amylase catalytic
DOU34_RS00125	COG0803	Belongs to the bacterial solute-binding protein 9 family
DOU34_RS00130	COG1121	(ABC) transporter
DOU34_RS00135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DOU34_RS00140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS00145	COG2310	stress, protein
DOU34_RS00150	COG2310	stress, protein
DOU34_RS00155	COG2310	stress, protein
DOU34_RS00160	COG0861	Integral membrane protein TerC family
DOU34_RS00170	COG3853	Toxic anion resistance protein (TelA)
DOU34_RS00175	COG0477	Major facilitator Superfamily
DOU34_RS00180	COG0517	IMP dehydrogenase activity
DOU34_RS00180	COG4175	Glycine betaine
DOU34_RS00185	COG4176	ABC-type proline glycine betaine transport system permease component
DOU34_RS00190	COG2113	Glycine betaine
DOU34_RS00195	COG1473	amidohydrolase
DOU34_RS00200	COG1288	antiporter activity
DOU34_RS00210	COG0366	Alpha amylase catalytic
DOU34_RS00220	COG2814	Major facilitator Superfamily
DOU34_RS00225	COG1846	Transcriptional regulator
DOU34_RS00230	COG1280	lysine exporter protein (LysE YggA)
DOU34_RS00235	COG3403	YqcI/YcgG family
DOU34_RS00240	COG1113	amino acid transport
DOU34_RS00245	COG3665	Urea carboxylase-associated protein
DOU34_RS00265	COG1082	Xylose isomerase domain protein TIM barrel
DOU34_RS00270	COG2271	Major facilitator Superfamily
DOU34_RS00275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOU34_RS00280	COG3458	cephalosporin-C deacetylase activity
DOU34_RS00285	COG3541	Predicted nucleotidyltransferase
DOU34_RS00290	COG0506	proline dehydrogenase activity
DOU34_RS00295	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS00300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOU34_RS00305	COG2508	Transcriptional regulator
DOU34_RS00315	COG1587	Uroporphyrinogen-III synthase
DOU34_RS00315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DOU34_RS00320	COG2146	nitrite reductase [NAD(P)H] activity
DOU34_RS00325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOU34_RS00330	COG0243	molybdopterin cofactor binding
DOU34_RS00335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOU34_RS00340	COG2223	nitrite transmembrane transporter activity
DOU34_RS00345	COG0523	cobalamin synthesis protein
DOU34_RS00350	COG1063	alcohol dehydrogenase
DOU34_RS00355	COG1714	RDD family
DOU34_RS00365	COG2723	6-phospho-beta-galactosidase activity
DOU34_RS00375	COG3209	COG3209 Rhs family protein
DOU34_RS00380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DOU34_RS00385	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DOU34_RS00390	COG1733	regulation of RNA biosynthetic process
DOU34_RS00400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS00405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS00410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS00415	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DOU34_RS00430	COG0697	spore germination
DOU34_RS00435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS00445	COG2364	Membrane
DOU34_RS00450	COG1126	abc transporter atp-binding protein
DOU34_RS00455	COG0765	amino acid transport
DOU34_RS00460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS00465	COG0583	DNA-binding transcription factor activity
DOU34_RS00470	COG0163	prenyltransferase activity
DOU34_RS00475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DOU34_RS00490	COG3104	oligopeptide transport
DOU34_RS00495	COG5434	Belongs to the glycosyl hydrolase 28 family
DOU34_RS00505	COG0697	spore germination
DOU34_RS00515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DOU34_RS00520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS00525	COG0456	acetyltransferase
DOU34_RS00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS00535	COG0765	amino acid transport
DOU34_RS00540	COG1126	abc transporter atp-binding protein
DOU34_RS00545	COG1473	amidohydrolase
DOU34_RS00550	COG2079	MmgE PrpD family protein
DOU34_RS00555	COG1136	(ABC) transporter
DOU34_RS00560	COG0577	efflux transmembrane transporter activity
DOU34_RS00565	COG0745	RESPONSE REGULATOR receiver
DOU34_RS00570	COG3850	Histidine kinase
DOU34_RS00570	COG5002	protein histidine kinase activity
DOU34_RS00575	COG0457	Tetratricopeptide repeat
DOU34_RS00590	COG0527	aspartate kinase activity
DOU34_RS00595	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS00600	COG4605	iron ion homeostasis
DOU34_RS00605	COG4604	ABC transporter, ATP-binding protein
DOU34_RS00610	COG4607	ABC-type enterochelin transport system periplasmic component
DOU34_RS00615	COG2814	Major facilitator Superfamily
DOU34_RS00620	COG1309	transcriptional regulator
DOU34_RS00625	COG0778	Nitroreductase
DOU34_RS00630	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DOU34_RS00635	COG0640	Transcriptional regulator
DOU34_RS00640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS00645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS00650	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS00655	COG4975	Glucose uptake
DOU34_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS00665	COG4549	nuclear export factor GLE1
DOU34_RS00670	COG1276	copper resistance
DOU34_RS00670	COG2372	response to copper ion
DOU34_RS00675	COG1349	DNA-binding transcription factor activity
DOU34_RS00685	COG2213	PTS system mannitol-specific
DOU34_RS00690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS00700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOU34_RS00710	COG0561	phosphatase activity
DOU34_RS00720	COG1914	H( )-stimulated, divalent metal cation uptake system
DOU34_RS00730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DOU34_RS00735	COG1984	allophanate hydrolase subunit 2
DOU34_RS00740	COG1414	Transcriptional regulator
DOU34_RS00745	COG2755	lipolytic protein G-D-S-L family
DOU34_RS00755	COG2329	Antibiotic biosynthesis monooxygenase
DOU34_RS00760	COG0768	penicillin binding
DOU34_RS00765	COG4989	oxidoreductase activity
DOU34_RS00770	COG3711	transcriptional antiterminator
DOU34_RS00775	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS00785	COG1917	Cupin 2, conserved barrel domain protein
DOU34_RS00790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS00795	COG3871	stress protein (general stress protein 26)
DOU34_RS00805	COG2814	Major facilitator Superfamily
DOU34_RS00810	COG1522	sequence-specific DNA binding
DOU34_RS00815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOU34_RS00815	COG0551	DNA topoisomerase type I activity
DOU34_RS00820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DOU34_RS00825	COG3706	GGDEF domain
DOU34_RS00830	COG5298	Protein conserved in bacteria
DOU34_RS00835	COG1215	transferase activity, transferring glycosyl groups
DOU34_RS00845	COG0531	amino acid
DOU34_RS00850	COG0494	nUDIX hydrolase
DOU34_RS00855	COG0028	Belongs to the TPP enzyme family
DOU34_RS00885	COG1794	racemase activity, acting on amino acids and derivatives
DOU34_RS00920	COG1914	H( )-stimulated, divalent metal cation uptake system
DOU34_RS00935	COG4876	unkown
DOU34_RS00945	COG2076	Multidrug Resistance protein
DOU34_RS00950	COG2217	Heavy metal translocating P-type atpase
DOU34_RS00955	COG3729	General stress protein
DOU34_RS00960	COG0662	Cupin 2, conserved barrel domain protein
DOU34_RS00965	COG2329	Antibiotic biosynthesis monooxygenase
DOU34_RS00970	COG3546	catalase activity
DOU34_RS00975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DOU34_RS00980	COG3290	protein histidine kinase activity
DOU34_RS00985	COG4565	transcriptional regulatory protein
DOU34_RS00990	COG1301	dicarboxylic acid transport
DOU34_RS00995	COG0628	permease
DOU34_RS01000	COG1131	(ABC) transporter
DOU34_RS01005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DOU34_RS01015	COG1960	acyl-CoA dehydrogenase activity
DOU34_RS01030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOU34_RS01035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS01045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DOU34_RS01050	COG0513	Belongs to the DEAD box helicase family
DOU34_RS01055	COG3402	PFAM membrane-flanked domain
DOU34_RS01060	COG3428	Bacterial PH domain
DOU34_RS01065	COG0705	Rhomboid family
DOU34_RS01075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DOU34_RS01080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOU34_RS01085	COG0864	Transcriptional regulator
DOU34_RS01090	COG2337	Toxic component of a toxin-antitoxin (TA) module
DOU34_RS01095	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS01100	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS01105	COG2172	sigma factor antagonist activity
DOU34_RS01110	COG2208	phosphoserine phosphatase activity
DOU34_RS01115	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS01125	COG1191	sigma factor activity
DOU34_RS01130	COG2208	phosphoserine phosphatase activity
DOU34_RS01135	COG2183	response to ionizing radiation
DOU34_RS01200	COG1959	2 iron, 2 sulfur cluster binding
DOU34_RS01205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOU34_RS01210	COG1090	epimerase
DOU34_RS01215	COG0457	Tetratricopeptide repeat
DOU34_RS01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
DOU34_RS01235	COG0477	Major facilitator Superfamily
DOU34_RS01240	COG1846	Transcriptional regulator
DOU34_RS01250	COG2030	dehydratase
DOU34_RS01265	COG1959	2 iron, 2 sulfur cluster binding
DOU34_RS01270	COG2910	NAD(P)H-binding
DOU34_RS01275	COG1309	transcriptional regulator
DOU34_RS01280	COG0300	oxidoreductase activity
DOU34_RS01290	COG3239	Fatty acid desaturase
DOU34_RS01300	COG1278	Cold shock
DOU34_RS01305	COG1329	Transcriptional regulator
DOU34_RS01310	COG1794	racemase activity, acting on amino acids and derivatives
DOU34_RS01325	COG3621	Patatin-like phospholipase
DOU34_RS01335	COG0662	Cupin 2, conserved barrel domain protein
DOU34_RS01350	COG0277	FAD linked oxidase domain protein
DOU34_RS01375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOU34_RS01410	COG0351	phosphomethylpyrimidine kinase
DOU34_RS01425	COG1064	alcohol dehydrogenase
DOU34_RS01430	COG0789	Transcriptional regulator
DOU34_RS01440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS01475	COG2814	Major facilitator Superfamily
DOU34_RS01480	COG1309	transcriptional regulator
DOU34_RS01485	COG0697	spore germination
DOU34_RS01490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS01495	COG5577	PFAM Coat F domain
DOU34_RS01505	COG1063	alcohol dehydrogenase
DOU34_RS01510	COG5577	PFAM Coat F domain
DOU34_RS01525	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DOU34_RS01530	COG0488	(ABC) transporter
DOU34_RS01535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS01540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS01550	COG2814	Major facilitator Superfamily
DOU34_RS01555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DOU34_RS01565	COG0730	response to heat
DOU34_RS01570	COG0456	acetyltransferase
DOU34_RS01575	COG4978	Transcriptional regulator
DOU34_RS01575	COG0789	Transcriptional regulator
DOU34_RS01580	COG0697	spore germination
DOU34_RS01585	COG1051	belongs to the nudix hydrolase family
DOU34_RS01590	COG2226	methyltransferase
DOU34_RS01595	COG0473	3-isopropylmalate dehydrogenase activity
DOU34_RS01600	COG1802	Transcriptional regulator
DOU34_RS01605	COG1819	glycosyl
DOU34_RS01620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DOU34_RS01625	COG1388	LysM domain
DOU34_RS01630	COG2814	Major facilitator Superfamily
DOU34_RS01635	COG2188	Transcriptional regulator
DOU34_RS01640	COG2186	Transcriptional regulator
DOU34_RS01645	COG2807	transmembrane transport
DOU34_RS01650	COG2076	Multidrug Resistance protein
DOU34_RS01655	COG2076	Multidrug Resistance protein
DOU34_RS01660	COG1309	transcriptional regulator
DOU34_RS01665	COG0531	amino acid
DOU34_RS01675	COG3832	glyoxalase III activity
DOU34_RS01680	COG0604	alcohol dehydrogenase
DOU34_RS01685	COG2814	Major facilitator Superfamily
DOU34_RS01725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DOU34_RS01730	COG0802	atpase or kinase
DOU34_RS01735	COG1214	PFAM Peptidase M22, glycoprotease
DOU34_RS01740	COG0456	acetyltransferase
DOU34_RS01745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOU34_RS01750	COG0488	(ABC) transporter
DOU34_RS01765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOU34_RS01770	COG0805	protein transport
DOU34_RS01780	COG1266	CAAX protease self-immunity
DOU34_RS01820	COG1073	alpha beta
DOU34_RS01825	COG0457	Tetratricopeptide repeat
DOU34_RS01830	COG1063	alcohol dehydrogenase
DOU34_RS01835	COG2211	Major facilitator Superfamily
DOU34_RS01840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOU34_RS01850	COG1842	Phage shock protein A
DOU34_RS01855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOU34_RS01860	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DOU34_RS01865	COG4260	virion core protein, lumpy skin disease virus
DOU34_RS01870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DOU34_RS01870	COG2755	lipolytic protein G-D-S-L family
DOU34_RS01885	COG1595	DNA-templated transcription, initiation
DOU34_RS01890	COG1063	alcohol dehydrogenase
DOU34_RS01895	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DOU34_RS01900	COG0823	Involved in the tonB-independent uptake of proteins
DOU34_RS01910	COG2132	Multicopper oxidase
DOU34_RS01915	COG1113	amino acid transport
DOU34_RS01920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOU34_RS01925	COG0714	Associated with various cellular activities
DOU34_RS01930	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DOU34_RS01935	COG1305	Transglutaminase-like
DOU34_RS01960	COG2252	PERMEase
DOU34_RS01965	COG3064	Membrane
DOU34_RS01985	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOU34_RS01990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOU34_RS01995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOU34_RS02000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DOU34_RS02005	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOU34_RS02020	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOU34_RS02030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOU34_RS02035	COG0138	bifunctional purine biosynthesis protein purh
DOU34_RS02040	COG0151	Belongs to the GarS family
DOU34_RS02050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DOU34_RS02055	COG1470	cell adhesion involved in biofilm formation
DOU34_RS02060	COG4496	protein, YerC YecD
DOU34_RS02065	COG0069	glutamate synthase activity
DOU34_RS02080	COG0210	DNA helicase
DOU34_RS02095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DOU34_RS02100	COG1285	pathogenesis
DOU34_RS02105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOU34_RS02125	COG1309	transcriptional regulator
DOU34_RS02130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOU34_RS02135	COG1597	lipid kinase activity
DOU34_RS02140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOU34_RS02175	COG5444	nuclease activity
DOU34_RS02205	COG3546	catalase activity
DOU34_RS02210	COG0454	-acetyltransferase
DOU34_RS02220	COG2323	membrane
DOU34_RS02225	COG2329	Antibiotic biosynthesis monooxygenase
DOU34_RS02230	COG0346	lactoylglutathione lyase activity
DOU34_RS02240	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS02245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DOU34_RS02250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DOU34_RS02255	COG4208	sulfate ABC transporter
DOU34_RS02265	COG5583	Uncharacterized small protein (DUF2292)
DOU34_RS02270	COG0196	riboflavin kinase activity
DOU34_RS02275	COG0670	Belongs to the BI1 family
DOU34_RS02285	COG1846	Transcriptional regulator
DOU34_RS02290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOU34_RS02300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOU34_RS02300	COG2124	cytochrome p450
DOU34_RS02305	COG1368	sulfuric ester hydrolase activity
DOU34_RS02310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DOU34_RS02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS02320	COG1442	glycosyl transferase family 8
DOU34_RS02325	COG1216	Glycosyl transferase, family 2
DOU34_RS02330	COG1442	glycosyl transferase family 8
DOU34_RS02335	COG2223	nitrite transmembrane transporter activity
DOU34_RS02340	COG0531	amino acid
DOU34_RS02345	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS02350	COG0840	transmembrane signaling receptor activity
DOU34_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS02360	COG0457	Tetratricopeptide repeat
DOU34_RS02360	COG0463	Glycosyl transferase, family 2
DOU34_RS02365	COG0488	(ABC) transporter
DOU34_RS02370	COG0789	Transcriptional regulator
DOU34_RS02375	COG2814	Major facilitator Superfamily
DOU34_RS02380	COG0488	(ABC) transporter
DOU34_RS02385	COG0513	Belongs to the DEAD box helicase family
DOU34_RS02390	COG0456	acetyltransferase
DOU34_RS02395	COG2130	NADP-dependent
DOU34_RS02410	COG3866	Pectate lyase
DOU34_RS02415	COG0471	metal ion transport
DOU34_RS02445	COG3290	protein histidine kinase activity
DOU34_RS02450	COG4565	transcriptional regulatory protein
DOU34_RS02455	COG3181	Tripartite tricarboxylate transporter family receptor
DOU34_RS02460	COG2851	Citrate transporter
DOU34_RS02465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS02470	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DOU34_RS02480	COG2258	MOSC domain
DOU34_RS02500	COG0024	Methionine aminopeptidase
DOU34_RS02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS02505	COG1263	PTS System
DOU34_RS02515	COG1368	sulfuric ester hydrolase activity
DOU34_RS02525	COG0071	Belongs to the small heat shock protein (HSP20) family
DOU34_RS02540	COG1263	PTS System
DOU34_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS02545	COG0366	Alpha amylase catalytic
DOU34_RS02550	COG2188	Transcriptional regulator
DOU34_RS02555	COG0778	Nitroreductase
DOU34_RS02570	COG0737	Belongs to the 5'-nucleotidase family
DOU34_RS02575	COG0693	protein deglycase activity
DOU34_RS02580	COG1609	Transcriptional regulator
DOU34_RS02595	COG2814	Major facilitator Superfamily
DOU34_RS02605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOU34_RS02610	COG4980	gas vesicle protein
DOU34_RS02615	COG1295	ribonuclease BN
DOU34_RS02620	COG0477	Major facilitator Superfamily
DOU34_RS02625	COG0387	Pfam Sodium calcium exchanger
DOU34_RS02635	COG0668	transmembrane transport
DOU34_RS02640	COG0535	radical SAM domain protein
DOU34_RS02650	COG0726	polysaccharide deacetylase
DOU34_RS02655	COG2084	Dehydrogenase
DOU34_RS02665	COG0598	Magnesium transport protein CorA
DOU34_RS02670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DOU34_RS02675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOU34_RS02685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOU34_RS02690	COG4637	Psort location Cytoplasmic, score
DOU34_RS02695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DOU34_RS02700	COG0022	dehydrogenase e1 component
DOU34_RS02705	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOU34_RS02710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOU34_RS02715	COG3284	Transcriptional regulator
DOU34_RS02725	COG1486	melibiose metabolic process
DOU34_RS02730	COG1737	Transcriptional regulator
DOU34_RS02735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS02735	COG1263	PTS System
DOU34_RS02740	COG1132	(ABC) transporter
DOU34_RS02745	COG1132	(ABC) transporter
DOU34_RS02750	COG2259	Doxx family
DOU34_RS02755	COG2514	catechol 2,3-dioxygenase activity
DOU34_RS02770	COG1695	Transcriptional regulator
DOU34_RS02775	COG2249	NAD(P)H dehydrogenase (quinone) activity
DOU34_RS02780	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DOU34_RS02790	COG3848	Pyruvate phosphate dikinase
DOU34_RS02790	COG0574	Belongs to the PEP-utilizing enzyme family
DOU34_RS02795	COG2732	(Barnase) inhibitor
DOU34_RS02800	COG2318	DinB family
DOU34_RS02805	COG2814	Major facilitator Superfamily
DOU34_RS02810	COG1846	Transcriptional regulator
DOU34_RS02815	COG0392	lysyltransferase activity
DOU34_RS02815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOU34_RS02820	COG0384	phenazine biosynthesis protein PhzF
DOU34_RS02825	COG0778	Nitroreductase
DOU34_RS02840	COG1090	epimerase
DOU34_RS02855	COG2814	Major facilitator Superfamily
DOU34_RS02865	COG3591	Belongs to the peptidase S1B family
DOU34_RS02880	COG3103	Sh3 type 3 domain protein
DOU34_RS02885	COG5658	integral membrane protein
DOU34_RS02890	COG0596	Alpha beta hydrolase
DOU34_RS02895	COG0463	Glycosyl transferase, family 2
DOU34_RS02900	COG4485	Bacterial membrane protein, YfhO
DOU34_RS02905	COG1988	membrane-bound metal-dependent
DOU34_RS02910	COG1194	a g-specific adenine glycosylase
DOU34_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS02940	COG1132	(ABC) transporter
DOU34_RS02945	COG4129	membrane
DOU34_RS02955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DOU34_RS02960	COG0735	belongs to the Fur family
DOU34_RS03070	COG1757	Na H antiporter
DOU34_RS03075	COG3340	Belongs to the peptidase S51 family
DOU34_RS03095	COG0747	negative chemotaxis
DOU34_RS03100	COG0601	transmembrane transport
DOU34_RS03105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOU34_RS03110	COG0444	Belongs to the ABC transporter superfamily
DOU34_RS03115	COG4608	Belongs to the ABC transporter superfamily
DOU34_RS03120	COG0753	catalase activity
DOU34_RS03130	COG1116	anion transmembrane transporter activity
DOU34_RS03135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DOU34_RS03140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOU34_RS03160	COG1476	TRANSCRIPTIONal
DOU34_RS03170	COG3382	B3 4 domain protein
DOU34_RS03175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOU34_RS03185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DOU34_RS03190	COG0789	Transcriptional regulator
DOU34_RS03195	COG1664	Polymer-forming cytoskeletal
DOU34_RS03200	COG1664	Polymer-forming cytoskeletal
DOU34_RS03210	COG2766	serine protein kinase
DOU34_RS03225	COG1846	Transcriptional regulator
DOU34_RS03230	COG1566	PFAM secretion protein HlyD family protein
DOU34_RS03235	COG2814	Major facilitator Superfamily
DOU34_RS03240	COG0655	NAD(P)H dehydrogenase (quinone) activity
DOU34_RS03255	COG1725	Transcriptional regulator
DOU34_RS03260	COG1131	(ABC) transporter
DOU34_RS03265	COG1131	(ABC) transporter
DOU34_RS03270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DOU34_RS03275	COG1278	Cold shock
DOU34_RS03285	COG1464	Belongs to the NlpA lipoprotein family
DOU34_RS03290	COG3706	GGDEF domain
DOU34_RS03295	COG1823	symporter activity
DOU34_RS03315	COG5577	PFAM Coat F domain
DOU34_RS03320	COG0737	Belongs to the 5'-nucleotidase family
DOU34_RS03320	COG1525	nuclease
DOU34_RS03320	COG4085	toxin activity
DOU34_RS03325	COG3764	Sortase (surface protein transpeptidase)
DOU34_RS03330	COG0564	pseudouridine synthase activity
DOU34_RS03340	COG0517	IMP dehydrogenase activity
DOU34_RS03345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DOU34_RS03350	COG3153	acetyltransferase
DOU34_RS03350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOU34_RS03355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DOU34_RS03360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DOU34_RS03365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DOU34_RS03375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DOU34_RS03380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOU34_RS03385	COG2203	Gaf domain
DOU34_RS03385	COG4585	Histidine kinase
DOU34_RS03390	COG2197	response regulator
DOU34_RS03395	COG0431	NADPH-dependent FMN reductase
DOU34_RS03410	COG0791	NLP P60 protein
DOU34_RS03410	COG1388	LysM domain
DOU34_RS03415	COG1959	2 iron, 2 sulfur cluster binding
DOU34_RS03425	COG0668	transmembrane transport
DOU34_RS03430	COG2719	SpoVR family
DOU34_RS03435	COG1785	Belongs to the alkaline phosphatase family
DOU34_RS03440	COG1388	LysM domain
DOU34_RS03440	COG0791	NLP P60 protein
DOU34_RS03445	COG0583	DNA-binding transcription factor activity
DOU34_RS03450	COG0372	Belongs to the citrate synthase family
DOU34_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS03465	COG0733	neurotransmitter:sodium symporter activity
DOU34_RS03480	COG1595	DNA-templated transcription, initiation
DOU34_RS03485	COG0204	Acyl-transferase
DOU34_RS03490	COG1253	flavin adenine dinucleotide binding
DOU34_RS03495	COG0789	Transcriptional regulator
DOU34_RS03500	COG0436	Aminotransferase
DOU34_RS03505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DOU34_RS03510	COG1253	flavin adenine dinucleotide binding
DOU34_RS03515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOU34_RS03520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOU34_RS03525	COG0584	glycerophosphoryl diester phosphodiesterase
DOU34_RS03535	COG0668	transmembrane transport
DOU34_RS03540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOU34_RS03545	COG0726	polysaccharide deacetylase
DOU34_RS03550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS03555	COG3226	Transcriptional regulator
DOU34_RS03565	COG0589	response to stress
DOU34_RS03570	COG1132	(ABC) transporter
DOU34_RS03575	COG1132	(ABC) transporter
DOU34_RS03580	COG0702	epimerase
DOU34_RS03600	COG0189	ligase activity
DOU34_RS03605	COG0189	ligase activity
DOU34_RS03620	COG4335	DNA alkylation repair
DOU34_RS03625	COG0561	phosphatase activity
DOU34_RS03630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOU34_RS03640	COG0475	glutathione-regulated potassium exporter activity
DOU34_RS03645	COG0490	domain, Protein
DOU34_RS03655	COG1024	Enoyl-CoA hydratase
DOU34_RS03665	COG4152	abc transporter atp-binding protein
DOU34_RS03670	COG1668	transmembrane transport
DOU34_RS03675	COG0420	3'-5' exonuclease activity
DOU34_RS03680	COG4717	serine-type aminopeptidase activity
DOU34_RS03695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOU34_RS03740	COG4980	gas vesicle protein
DOU34_RS03755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOU34_RS03760	COG0537	adenosine 5'-monophosphoramidase activity
DOU34_RS03765	COG1131	(ABC) transporter
DOU34_RS03770	COG4473	ABC transporter
DOU34_RS03780	COG1473	amidohydrolase
DOU34_RS03785	COG3069	C4-dicarboxylate transmembrane transporter activity
DOU34_RS03790	COG2329	Antibiotic biosynthesis monooxygenase
DOU34_RS03795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOU34_RS03805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DOU34_RS03810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DOU34_RS03815	COG1309	transcriptional regulator
DOU34_RS03820	COG1511	domain protein
DOU34_RS03825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOU34_RS03835	COG1363	Peptidase, m42
DOU34_RS03840	COG1301	dicarboxylic acid transport
DOU34_RS03850	COG1234	tRNA 3'-trailer cleavage
DOU34_RS03855	COG0095	Lipoate-protein ligase
DOU34_RS03860	COG0702	epimerase
DOU34_RS03865	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS03875	COG0501	Belongs to the peptidase M48B family
DOU34_RS03880	COG1404	Belongs to the peptidase S8 family
DOU34_RS03890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DOU34_RS03895	COG0406	alpha-ribazole phosphatase activity
DOU34_RS03900	COG0183	Belongs to the thiolase family
DOU34_RS03905	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS03910	COG1268	BioY protein
DOU34_RS03915	COG0840	transmembrane signaling receptor activity
DOU34_RS03920	COG0723	plastoquinol--plastocyanin reductase activity
DOU34_RS03920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOU34_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS03935	COG4903	ComK protein
DOU34_RS03945	COG5646	InterPro IPR014922
DOU34_RS03970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOU34_RS03985	COG0398	Pfam SNARE associated Golgi protein
DOU34_RS03990	COG0681	Belongs to the peptidase S26 family
DOU34_RS04000	COG1846	Transcriptional regulator
DOU34_RS04005	COG3180	Ammonia monooxygenase
DOU34_RS04010	COG2814	Major facilitator Superfamily
DOU34_RS04020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DOU34_RS04025	COG2323	membrane
DOU34_RS04040	COG0420	3'-5' exonuclease activity
DOU34_RS04045	COG0419	ATPase involved in DNA repair
DOU34_RS04050	COG1403	HNH endonuclease
DOU34_RS04090	COG0179	Fumarylacetoacetate (FAA) hydrolase
DOU34_RS04110	COG0367	asparagine synthase
DOU34_RS04115	COG1562	ergosterol biosynthetic process
DOU34_RS04120	COG0534	Mate efflux family protein
DOU34_RS04125	COG1917	Cupin 2, conserved barrel domain protein
DOU34_RS04125	COG2207	Transcriptional regulator
DOU34_RS04130	COG2318	DinB family
DOU34_RS04140	COG1357	PFAM Pentapeptide repeats (8 copies)
DOU34_RS04145	COG2153	protein acetylation
DOU34_RS04150	COG0646	methionine synthase
DOU34_RS04150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DOU34_RS04160	COG2996	Protein conserved in bacteria
DOU34_RS04165	COG1744	ABC transporter substrate-binding protein PnrA-like
DOU34_RS04170	COG0840	transmembrane signaling receptor activity
DOU34_RS04175	COG2124	cytochrome p450
DOU34_RS04190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS04205	COG0561	phosphatase activity
DOU34_RS04210	COG1073	alpha beta
DOU34_RS04215	COG2151	metal-sulfur cluster biosynthetic enzyme
DOU34_RS04225	COG0277	FAD linked oxidase domain protein
DOU34_RS04230	COG2271	Major facilitator Superfamily
DOU34_RS04240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DOU34_RS04250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOU34_RS04255	COG0505	Belongs to the CarA family
DOU34_RS04260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DOU34_RS04265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOU34_RS04285	COG2267	carboxylic ester hydrolase activity
DOU34_RS04295	COG1744	ABC transporter substrate-binding protein PnrA-like
DOU34_RS04310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOU34_RS04315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DOU34_RS04320	COG5504	Zn-dependent protease
DOU34_RS04325	COG0444	Belongs to the ABC transporter superfamily
DOU34_RS04330	COG4608	Belongs to the ABC transporter superfamily
DOU34_RS04340	COG0601	transmembrane transport
DOU34_RS04345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOU34_RS04355	COG2814	Major facilitator Superfamily
DOU34_RS04365	COG0180	Tryptophanyl-tRNA synthetase
DOU34_RS04370	COG4166	transmembrane transport
DOU34_RS04375	COG0601	transmembrane transport
DOU34_RS04380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOU34_RS04385	COG0444	Belongs to the ABC transporter superfamily
DOU34_RS04390	COG4608	Belongs to the ABC transporter superfamily
DOU34_RS04400	COG0456	acetyltransferase
DOU34_RS04405	COG1393	Belongs to the ArsC family
DOU34_RS04410	COG0861	Integral membrane protein TerC family
DOU34_RS04415	COG4862	establishment of competence for transformation
DOU34_RS04420	COG4469	Competence protein
DOU34_RS04425	COG1164	Oligoendopeptidase f
DOU34_RS04430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DOU34_RS04435	COG2346	COG2346, Truncated hemoglobins
DOU34_RS04440	COG0741	lytic transglycosylase activity
DOU34_RS04445	COG4116	CYTH
DOU34_RS04455	COG2357	RelA SpoT domain protein
DOU34_RS04460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOU34_RS04465	COG0564	pseudouridine synthase activity
DOU34_RS04475	COG0569	domain protein
DOU34_RS04475	COG0475	glutathione-regulated potassium exporter activity
DOU34_RS04480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DOU34_RS04485	COG0352	thiamine-phosphate diphosphorylase activity
DOU34_RS04490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOU34_RS04495	COG2104	thiamine diphosphate biosynthetic process
DOU34_RS04505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DOU34_RS04510	COG0351	phosphomethylpyrimidine kinase
DOU34_RS04515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DOU34_RS04570	COG0210	DNA helicase
DOU34_RS04590	COG1131	(ABC) transporter
DOU34_RS04600	COG2153	protein acetylation
DOU34_RS04610	COG2382	esterase
DOU34_RS04615	COG0626	cystathionine gamma-synthase activity
DOU34_RS04620	COG0626	cystathionine gamma-synthase activity
DOU34_RS04630	COG0582	viral genome integration into host DNA
DOU34_RS04635	COG2856	Zn peptidase
DOU34_RS04695	COG3935	DnaD domain protein
DOU34_RS04700	COG1484	DNA-dependent DNA replication
DOU34_RS04705	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DOU34_RS04735	COG1595	DNA-templated transcription, initiation
DOU34_RS04760	COG5484	DNA packaging
DOU34_RS04765	COG1783	phage Terminase large subunit
DOU34_RS04875	COG4824	toxin secretion phage lysis holin
DOU34_RS04880	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS04880	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS04900	COG5444	nuclease activity
DOU34_RS04955	COG5444	nuclease activity
DOU34_RS04975	COG0346	lactoylglutathione lyase activity
DOU34_RS04980	COG2367	Beta-lactamase
DOU34_RS04985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DOU34_RS04990	COG0477	Major facilitator Superfamily
DOU34_RS04995	COG1846	Transcriptional regulator
DOU34_RS05005	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DOU34_RS05010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOU34_RS05015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOU34_RS05020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS05020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS05025	COG1447	Phosphotransferase system cellobiose-specific component IIA
DOU34_RS05060	COG1285	pathogenesis
DOU34_RS05085	COG3383	formate dehydrogenase (NAD+) activity
DOU34_RS05090	COG2427	Protein of unknown function (DUF1641)
DOU34_RS05095	COG2124	cytochrome p450
DOU34_RS05100	COG1819	glycosyl
DOU34_RS05110	COG1587	Uroporphyrinogen-III synthase
DOU34_RS05115	COG0390	transport system, permease component
DOU34_RS05120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOU34_RS05125	COG0697	spore germination
DOU34_RS05130	COG4297	protein containing double-stranded beta helix domain
DOU34_RS05140	COG1252	NADH dehydrogenase
DOU34_RS05150	COG2211	Major facilitator Superfamily
DOU34_RS05155	COG1609	Transcriptional regulator
DOU34_RS05160	COG0246	Mannitol dehydrogenase
DOU34_RS05165	COG2721	sulfolactate sulfo-lyase activity
DOU34_RS05170	COG0730	response to heat
DOU34_RS05175	COG2318	DinB family
DOU34_RS05180	COG0457	Tetratricopeptide repeat
DOU34_RS05185	COG1388	LysM domain
DOU34_RS05185	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS05185	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS05195	COG4195	phage-related replication protein
DOU34_RS05200	COG2856	Zn peptidase
DOU34_RS05205	COG1396	sequence-specific DNA binding
DOU34_RS05215	COG1522	sequence-specific DNA binding
DOU34_RS05220	COG1484	DNA-dependent DNA replication
DOU34_RS05235	COG1595	DNA-templated transcription, initiation
DOU34_RS05240	COG3728	DNA packaging
DOU34_RS05240	COG5484	DNA packaging
DOU34_RS05245	COG1783	phage Terminase large subunit
DOU34_RS05250	COG5518	Phage portal protein
DOU34_RS05255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DOU34_RS05260	COG4653	Phage capsid family
DOU34_RS05310	COG5412	phage tail tape measure protein
DOU34_RS05310	COG3953	SLT domain
DOU34_RS05310	COG5412	phage tail tape measure protein
DOU34_RS05310	COG3953	SLT domain
DOU34_RS05310	COG5412	phage tail tape measure protein
DOU34_RS05310	COG3953	SLT domain
DOU34_RS05315	COG1652	LysM domain
DOU34_RS05320	COG4193	domain, Protein
DOU34_RS05330	COG3628	GPW Gp25 family protein
DOU34_RS05335	COG3299	homolog of phage Mu protein gp47
DOU34_RS05340	COG3778	Protein conserved in bacteria
DOU34_RS05380	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS05380	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS05395	COG0306	phosphate transporter
DOU34_RS05400	COG1392	Phosphate transport regulator
DOU34_RS05405	COG0531	amino acid
DOU34_RS05410	COG0346	lactoylglutathione lyase activity
DOU34_RS05415	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOU34_RS05420	COG0463	Glycosyl transferase, family 2
DOU34_RS05425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOU34_RS05430	COG0477	Major facilitator Superfamily
DOU34_RS05435	COG2362	D-Aminopeptidase
DOU34_RS05440	COG0601	transmembrane transport
DOU34_RS05445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOU34_RS05450	COG0444	Belongs to the ABC transporter superfamily
DOU34_RS05455	COG4166	transmembrane transport
DOU34_RS05460	COG1619	proteins homologs of microcin C7 resistance protein MccF
DOU34_RS05470	COG0791	NLP P60 protein
DOU34_RS05475	COG4608	Belongs to the ABC transporter superfamily
DOU34_RS05480	COG2706	6-phosphogluconolactonase activity
DOU34_RS05485	COG1834	amidinotransferase
DOU34_RS05490	COG1607	acyl-coa hydrolase
DOU34_RS05495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS05500	COG2076	Multidrug Resistance protein
DOU34_RS05505	COG2076	Multidrug Resistance protein
DOU34_RS05510	COG0788	formyltetrahydrofolate deformylase activity
DOU34_RS05515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOU34_RS05525	COG1764	response to oxidative stress
DOU34_RS05530	COG1846	Transcriptional regulator
DOU34_RS05535	COG1764	response to oxidative stress
DOU34_RS05550	COG0463	Glycosyl transferase, family 2
DOU34_RS05550	COG0457	Tetratricopeptide repeat
DOU34_RS05560	COG2814	Major facilitator Superfamily
DOU34_RS05565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOU34_RS05575	COG1404	Belongs to the peptidase S8 family
DOU34_RS05580	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS05585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOU34_RS05590	COG1122	ATPase activity
DOU34_RS05595	COG4721	ABC-type cobalt transport system, permease component
DOU34_RS05600	COG1388	LysM domain
DOU34_RS05600	COG3858	chitin binding
DOU34_RS05620	COG2239	Acts as a magnesium transporter
DOU34_RS05625	COG0789	Transcriptional regulator
DOU34_RS05640	COG1846	Transcriptional regulator
DOU34_RS05645	COG0726	polysaccharide deacetylase
DOU34_RS05650	COG1793	dna ligase
DOU34_RS05650	COG3285	dna ligase
DOU34_RS05655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DOU34_RS05660	COG0586	Pfam SNARE associated Golgi protein
DOU34_RS05665	COG0861	Integral membrane protein TerC family
DOU34_RS05670	COG1191	sigma factor activity
DOU34_RS05695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DOU34_RS05700	COG2323	membrane
DOU34_RS05710	COG3594	Acyltransferase
DOU34_RS05715	COG5002	protein histidine kinase activity
DOU34_RS05720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOU34_RS05735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOU34_RS05740	COG0436	Aminotransferase
DOU34_RS05770	COG3852	Histidine kinase
DOU34_RS05775	COG1846	Transcriptional regulator
DOU34_RS05780	COG1360	Flagellar Motor Protein
DOU34_RS05785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DOU34_RS05790	COG0542	response to heat
DOU34_RS05800	COG3949	Membrane
DOU34_RS05815	COG0720	synthase
DOU34_RS05820	COG0602	queuosine metabolic process
DOU34_RS05830	COG1733	regulation of RNA biosynthetic process
DOU34_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS05845	COG1388	LysM domain
DOU34_RS05845	COG4641	Protein conserved in bacteria
DOU34_RS05850	COG1388	LysM domain
DOU34_RS05855	COG3858	chitin binding
DOU34_RS05865	COG4873	Protein conserved in bacteria
DOU34_RS05875	COG3773	Cell wall hydrolase
DOU34_RS05880	COG2244	polysaccharide biosynthetic process
DOU34_RS05885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS05890	COG2217	Heavy metal translocating P-type atpase
DOU34_RS05895	COG0006	proline dipeptidase activity
DOU34_RS05900	COG1609	Transcriptional regulator
DOU34_RS05905	COG3711	transcriptional antiterminator
DOU34_RS05910	COG1263	PTS System
DOU34_RS05910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS05910	COG2190	(PTS) system
DOU34_RS05915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS05920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOU34_RS05930	COG1533	DNA photolyase activity
DOU34_RS05935	COG0840	transmembrane signaling receptor activity
DOU34_RS05940	COG2084	Dehydrogenase
DOU34_RS05945	COG2340	Cysteine-rich secretory protein family
DOU34_RS05950	COG0768	penicillin binding
DOU34_RS05955	COG4191	Histidine kinase
DOU34_RS05960	COG0436	Aminotransferase
DOU34_RS05970	COG0784	Response regulator, receiver
DOU34_RS05970	COG0835	chemotaxis
DOU34_RS05980	COG2814	Major facilitator Superfamily
DOU34_RS05985	COG1376	ErfK ybiS ycfS ynhG family protein
DOU34_RS05990	COG1408	metallophosphoesterase
DOU34_RS05995	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS06005	COG2200	EAL domain
DOU34_RS06010	COG4703	Protein of unknown function (DUF1797)
DOU34_RS06015	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DOU34_RS06025	COG0517	IMP dehydrogenase activity
DOU34_RS06030	COG0583	DNA-binding transcription factor activity
DOU34_RS06035	COG0716	FMN binding
DOU34_RS06045	COG0716	FMN binding
DOU34_RS06065	COG0668	transmembrane transport
DOU34_RS06070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS06090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DOU34_RS06095	COG0303	'Molybdopterin
DOU34_RS06100	COG1763	Mo-molybdopterin cofactor biosynthetic process
DOU34_RS06105	COG0314	molybdopterin synthase activity
DOU34_RS06110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DOU34_RS06120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOU34_RS06125	COG1136	(ABC) transporter
DOU34_RS06130	COG0577	efflux transmembrane transporter activity
DOU34_RS06135	COG1349	DNA-binding transcription factor activity
DOU34_RS06140	COG1105	Belongs to the carbohydrate kinase PfkB family
DOU34_RS06145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS06145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOU34_RS06145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOU34_RS06150	COG0681	Belongs to the peptidase S26 family
DOU34_RS06160	COG0488	(ABC) transporter
DOU34_RS06165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOU34_RS06170	COG2309	aminopeptidase activity
DOU34_RS06180	COG1077	Cell shape determining protein MreB Mrl
DOU34_RS06190	COG2002	toxin-antitoxin pair type II binding
DOU34_RS06195	COG3852	Histidine kinase
DOU34_RS06200	COG2105	PFAM AIG2 family protein
DOU34_RS06200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DOU34_RS06205	COG0569	domain protein
DOU34_RS06215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOU34_RS06225	COG0561	phosphatase activity
DOU34_RS06230	COG0242	peptide deformylase activity
DOU34_RS06240	COG0497	DNA recombination
DOU34_RS06255	COG4221	oxidoreductase activity
DOU34_RS06255	COG3321	synthase
DOU34_RS06255	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS06255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS06260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS06260	COG0300	oxidoreductase activity
DOU34_RS06260	COG4221	oxidoreductase activity
DOU34_RS06260	COG3321	synthase
DOU34_RS06265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS06265	COG3321	synthase
DOU34_RS06265	COG4221	oxidoreductase activity
DOU34_RS06270	COG0300	oxidoreductase activity
DOU34_RS06270	COG3321	synthase
DOU34_RS06270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS06270	COG4221	oxidoreductase activity
DOU34_RS06275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS06275	COG0300	oxidoreductase activity
DOU34_RS06275	COG3321	synthase
DOU34_RS06275	COG4221	oxidoreductase activity
DOU34_RS06280	COG0300	oxidoreductase activity
DOU34_RS06280	COG3321	synthase
DOU34_RS06280	COG4221	oxidoreductase activity
DOU34_RS06280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS06285	COG3321	synthase
DOU34_RS06285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS06285	COG4221	oxidoreductase activity
DOU34_RS06290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DOU34_RS06295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DOU34_RS06300	COG0022	dehydrogenase e1 component
DOU34_RS06305	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOU34_RS06310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOU34_RS06315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS06330	COG1982	Orn Lys Arg decarboxylase major
DOU34_RS06355	COG0483	inositol monophosphate 1-phosphatase activity
DOU34_RS06365	COG3227	Zinc metalloprotease (Elastase)
DOU34_RS06370	COG1595	DNA-templated transcription, initiation
DOU34_RS06390	COG1217	gtp-binding protein TYPA
DOU34_RS06400	COG4896	Protein conserved in bacteria
DOU34_RS06415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DOU34_RS06420	COG2066	Belongs to the glutaminase family
DOU34_RS06430	COG0772	Belongs to the SEDS family
DOU34_RS06435	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DOU34_RS06450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DOU34_RS06450	COG2010	Cytochrome c
DOU34_RS06455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOU34_RS06460	COG1845	cytochrome c oxidase, subunit III
DOU34_RS06465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DOU34_RS06470	COG3336	cytochrome c oxidase
DOU34_RS06480	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DOU34_RS06485	COG2340	Cysteine-rich secretory protein family
DOU34_RS06500	COG3679	Belongs to the UPF0342 family
DOU34_RS06515	COG0742	ribosomal rna small subunit methyltransferase
DOU34_RS06525	COG3314	Sporulation integral membrane protein YlbJ
DOU34_RS06530	COG1752	Esterase of the alpha-beta hydrolase superfamily
DOU34_RS06535	COG3480	Lon protease (S16) C-terminal proteolytic domain
DOU34_RS06545	COG1399	metal-binding, possibly nucleic acid-binding protein
DOU34_RS06565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOU34_RS06585	COG4839	cell division protein FtsL
DOU34_RS06590	COG0768	penicillin binding
DOU34_RS06595	COG0768	penicillin binding
DOU34_RS06615	COG0772	Belongs to the SEDS family
DOU34_RS06630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DOU34_RS06635	COG0849	cell division
DOU34_RS06640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOU34_RS06645	COG1404	Belongs to the peptidase S8 family
DOU34_RS06645	COG4412	M6 family metalloprotease domain protein
DOU34_RS06655	COG1191	sigma factor activity
DOU34_RS06660	COG1191	sigma factor activity
DOU34_RS06665	COG1119	ATPase activity
DOU34_RS06670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOU34_RS06675	COG1873	PFAM PRC-barrel domain
DOU34_RS06680	COG1496	oxidoreductase activity
DOU34_RS06685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOU34_RS06695	COG0762	integral membrane protein
DOU34_RS06700	COG2302	S4 RNA-binding domain
DOU34_RS06705	COG3599	regulation of cell shape
DOU34_RS06715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOU34_RS06720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DOU34_RS06730	COG0564	pseudouridine synthase activity
DOU34_RS06740	COG2233	PERMEase
DOU34_RS06750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DOU34_RS06755	COG0505	Belongs to the CarA family
DOU34_RS06760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DOU34_RS06775	COG0284	orotidine-5'-phosphate decarboxylase activity
DOU34_RS06780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOU34_RS06790	COG0306	phosphate transporter
DOU34_RS06805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DOU34_RS06810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DOU34_RS06815	COG1648	precorrin-2 dehydrogenase activity
DOU34_RS06835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DOU34_RS06840	COG1561	YicC-like family, N-terminal region
DOU34_RS06850	COG0194	GDP metabolic process
DOU34_RS06860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOU34_RS06865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOU34_RS06870	COG0242	peptide deformylase activity
DOU34_RS06880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOU34_RS06880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOU34_RS06890	COG0631	protein serine/threonine phosphatase activity
DOU34_RS06895	COG2815	serine threonine protein kinase
DOU34_RS06895	COG0515	serine threonine protein kinase
DOU34_RS06905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DOU34_RS06910	COG1564	THIamine pyrophosphokinase
DOU34_RS06925	COG1302	Protein conserved in bacteria
DOU34_RS06930	COG1461	Dihydroxyacetone kinase
DOU34_RS06935	COG1760	l-serine dehydratase
DOU34_RS06940	COG1760	l-serine dehydratase
DOU34_RS06945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOU34_RS06960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DOU34_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS06980	COG1196	nuclear chromosome segregation
DOU34_RS06985	COG0552	protein localization to endoplasmic reticulum
DOU34_RS07000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOU34_RS07010	COG1837	Belongs to the UPF0109 family
DOU34_RS07035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOU34_RS07050	COG2257	FlhB HrpN YscU SpaS Family
DOU34_RS07060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DOU34_RS07065	COG0758	DNA mediated transformation
DOU34_RS07070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOU34_RS07080	COG4974	Belongs to the 'phage' integrase family
DOU34_RS07100	COG1815	bacterial-type flagellum-dependent cell motility
DOU34_RS07105	COG1558	bacterial-type flagellum-dependent cell motility
DOU34_RS07110	COG1677	Flagellar hook-basal body complex protein FliE
DOU34_RS07115	COG1766	The M ring may be actively involved in energy transduction
DOU34_RS07120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOU34_RS07125	COG1317	bacterial-type flagellum organization
DOU34_RS07130	COG1157	protein secretion by the type III secretion system
DOU34_RS07135	COG2882	bacterial-type flagellum organization
DOU34_RS07140	COG3334	PFAM MgtE intracellular
DOU34_RS07145	COG3144	bacterial-type flagellum assembly
DOU34_RS07150	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DOU34_RS07155	COG4786	Flagellar basal body rod
DOU34_RS07160	COG1582	Flagellar protein (FlbD)
DOU34_RS07165	COG1580	Controls the rotational direction of flagella during chemotaxis
DOU34_RS07170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOU34_RS07175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DOU34_RS07175	COG1776	CheC inhibitor of MCP methylation
DOU34_RS07180	COG2201	protein-glutamate methylesterase activity
DOU34_RS07185	COG3190	flagellar
DOU34_RS07190	COG1338	Plays a role in the flagellum-specific transport system
DOU34_RS07195	COG1987	bacterial-type flagellum assembly
DOU34_RS07200	COG1684	flagellar biosynthetic protein fliR
DOU34_RS07205	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOU34_RS07210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOU34_RS07215	COG1419	protein localization to endoplasmic reticulum
DOU34_RS07220	COG0455	bacterial-type flagellum organization
DOU34_RS07225	COG2201	protein-glutamate methylesterase activity
DOU34_RS07230	COG0643	Histidine kinase
DOU34_RS07230	COG2198	Histidine kinase
DOU34_RS07235	COG0835	chemotaxis
DOU34_RS07240	COG1776	CheC inhibitor of MCP methylation
DOU34_RS07250	COG1191	sigma factor activity
DOU34_RS07280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOU34_RS07285	COG4589	Belongs to the CDS family
DOU34_RS07295	COG0750	zinc metalloprotease
DOU34_RS07305	COG2176	DNA-directed DNA polymerase activity
DOU34_RS07315	COG0195	Participates in both transcription termination and antitermination
DOU34_RS07320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DOU34_RS07325	COG1358	cellular component organization or biogenesis
DOU34_RS07335	COG1550	Protein conserved in bacteria
DOU34_RS07350	COG0196	riboflavin kinase activity
DOU34_RS07365	COG0726	polysaccharide deacetylase
DOU34_RS07370	COG0612	Peptidase, M16
DOU34_RS07375	COG1873	PFAM PRC-barrel domain
DOU34_RS07380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOU34_RS07390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOU34_RS07395	COG0527	aspartate kinase activity
DOU34_RS07405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOU34_RS07410	COG0740	serine-type endopeptidase activity
DOU34_RS07420	COG4980	gas vesicle protein
DOU34_RS07420	COG1674	ftsk spoiiie
DOU34_RS07425	COG2188	Transcriptional regulator
DOU34_RS07430	COG2814	Major facilitator Superfamily
DOU34_RS07435	COG1846	Transcriptional regulator
DOU34_RS07440	COG1033	growth of symbiont in host cell
DOU34_RS07440	COG2409	Drug exporters of the RND superfamily
DOU34_RS07445	COG0612	Peptidase, M16
DOU34_RS07450	COG0612	Peptidase, M16
DOU34_RS07455	COG0300	oxidoreductase activity
DOU34_RS07470	COG1426	Protein conserved in bacteria
DOU34_RS07475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOU34_RS07490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DOU34_RS07500	COG1692	metallophosphoesterase
DOU34_RS07505	COG2359	stage V sporulation protein S
DOU34_RS07525	COG4550	Control of competence regulator ComK, YlbF/YmcA
DOU34_RS07545	COG0582	viral genome integration into host DNA
DOU34_RS07595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS07600	COG3425	synthase
DOU34_RS07605	COG1024	Enoyl-CoA hydratase
DOU34_RS07610	COG1024	Enoyl-CoA hydratase
DOU34_RS07615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS07615	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS07615	COG0300	oxidoreductase activity
DOU34_RS07615	COG3321	synthase
DOU34_RS07615	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS07620	COG3321	synthase
DOU34_RS07620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS07620	COG0300	oxidoreductase activity
DOU34_RS07620	COG4221	oxidoreductase activity
DOU34_RS07625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS07625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS07625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS07625	COG3321	synthase
DOU34_RS07625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS07625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS07625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS07625	COG3321	synthase
DOU34_RS07630	COG3321	synthase
DOU34_RS07630	COG4221	oxidoreductase activity
DOU34_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS07630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS07635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS07635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DOU34_RS07635	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DOU34_RS07635	COG3321	synthase
DOU34_RS07640	COG2124	cytochrome p450
DOU34_RS07645	COG3209	COG3209 Rhs family protein
DOU34_RS07650	COG3619	membrane
DOU34_RS07660	COG1404	Belongs to the peptidase S8 family
DOU34_RS07670	COG4195	phage-related replication protein
DOU34_RS07675	COG1764	response to oxidative stress
DOU34_RS07685	COG2076	Multidrug Resistance protein
DOU34_RS07725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOU34_RS07730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOU34_RS07735	COG4112	unkown
DOU34_RS07740	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS07755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOU34_RS07760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DOU34_RS07765	COG0789	Transcriptional regulator
DOU34_RS07770	COG0174	glutamine synthetase
DOU34_RS07785	COG3507	Belongs to the glycosyl hydrolase 43 family
DOU34_RS07800	COG1070	Carbohydrate kinase
DOU34_RS07805	COG3848	Pyruvate phosphate dikinase
DOU34_RS07805	COG0574	Belongs to the PEP-utilizing enzyme family
DOU34_RS07830	COG1064	alcohol dehydrogenase
DOU34_RS07860	COG0456	acetyltransferase
DOU34_RS07900	COG3397	chitin binding
DOU34_RS07910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS07920	COG5434	Belongs to the glycosyl hydrolase 28 family
DOU34_RS07925	COG0756	dUTP diphosphatase activity
DOU34_RS07935	COG4195	phage-related replication protein
DOU34_RS07965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DOU34_RS07975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOU34_RS07995	COG0785	Cytochrome C biogenesis protein
DOU34_RS08000	COG2201	protein-glutamate methylesterase activity
DOU34_RS08005	COG4846	Membrane protein involved in cytochrome C biogenesis
DOU34_RS08015	COG0071	Belongs to the small heat shock protein (HSP20) family
DOU34_RS08030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DOU34_RS08035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS08055	COG0824	Thioesterase
DOU34_RS08065	COG4841	protein insertion into membrane
DOU34_RS08075	COG1832	CoA-binding protein
DOU34_RS08080	COG0187	DNA topoisomerase II activity
DOU34_RS08085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOU34_RS08095	COG1115	amino acid carrier protein
DOU34_RS08105	COG1063	alcohol dehydrogenase
DOU34_RS08110	COG0800	Aldolase
DOU34_RS08115	COG1312	Catalyzes the dehydration of D-mannonate
DOU34_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS08125	COG1609	Transcriptional regulator
DOU34_RS08130	COG2271	Major facilitator Superfamily
DOU34_RS08155	COG1136	(ABC) transporter
DOU34_RS08155	COG0577	efflux transmembrane transporter activity
DOU34_RS08185	COG2205	protein histidine kinase activity
DOU34_RS08190	COG0745	RESPONSE REGULATOR receiver
DOU34_RS08200	COG3507	Belongs to the glycosyl hydrolase 43 family
DOU34_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS08235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DOU34_RS08240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOU34_RS08245	COG2610	gluconate transmembrane transporter activity
DOU34_RS08250	COG2124	cytochrome p450
DOU34_RS08270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DOU34_RS08280	COG2246	polysaccharide biosynthetic process
DOU34_RS08285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DOU34_RS08290	COG0586	Pfam SNARE associated Golgi protein
DOU34_RS08295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DOU34_RS08300	COG1024	Enoyl-CoA hydratase
DOU34_RS08305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOU34_RS08310	COG0511	ligase activity, forming carbon-carbon bonds
DOU34_RS08315	COG0439	Biotin carboxylase
DOU34_RS08320	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS08325	COG1960	acyl-CoA dehydrogenase activity
DOU34_RS08330	COG1649	PFAM Uncharacterised BCR, COG1649
DOU34_RS08340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS08340	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DOU34_RS08345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS08350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS08355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS08360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS08370	COG2027	D-alanyl-D-alanine carboxypeptidase
DOU34_RS08375	COG2017	converts alpha-aldose to the beta-anomer
DOU34_RS08380	COG0534	Mate efflux family protein
DOU34_RS08390	COG5444	nuclease activity
DOU34_RS08405	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS08405	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS08410	COG4824	toxin secretion phage lysis holin
DOU34_RS08430	COG5434	Belongs to the glycosyl hydrolase 28 family
DOU34_RS08435	COG1705	Flagellar rod assembly protein muramidase FlgJ
DOU34_RS08435	COG1388	LysM domain
DOU34_RS08510	COG1802	Transcriptional regulator
DOU34_RS08510	COG4626	Terminase
DOU34_RS08540	COG0582	viral genome integration into host DNA
DOU34_RS08545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DOU34_RS08640	COG4974	Belongs to the 'phage' integrase family
DOU34_RS08650	COG0582	viral genome integration into host DNA
DOU34_RS08655	COG0166	Belongs to the GPI family
DOU34_RS08660	COG0405	Gamma-glutamyltransferase
DOU34_RS08665	COG2814	Major facilitator Superfamily
DOU34_RS08670	COG0640	Transcriptional regulator
DOU34_RS08675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOU34_RS08690	COG0604	alcohol dehydrogenase
DOU34_RS08695	COG0493	'glutamate synthase
DOU34_RS08700	COG0067	glutamate synthase
DOU34_RS08700	COG0070	glutamate synthase
DOU34_RS08700	COG0069	glutamate synthase activity
DOU34_RS08705	COG0583	DNA-binding transcription factor activity
DOU34_RS08710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOU34_RS08725	COG0300	oxidoreductase activity
DOU34_RS08730	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOU34_RS08740	COG2814	Major facilitator Superfamily
DOU34_RS08745	COG1070	Carbohydrate kinase
DOU34_RS08750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DOU34_RS08755	COG0243	molybdopterin cofactor binding
DOU34_RS08785	COG5444	nuclease activity
DOU34_RS08790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOU34_RS08795	COG2207	Transcriptional regulator
DOU34_RS08795	COG0662	Cupin 2, conserved barrel domain protein
DOU34_RS08800	COG1309	transcriptional regulator
DOU34_RS08805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS08815	COG0640	Transcriptional regulator
DOU34_RS08820	COG0741	lytic transglycosylase activity
DOU34_RS08825	COG2322	membrane
DOU34_RS08840	COG1619	proteins homologs of microcin C7 resistance protein MccF
DOU34_RS08850	COG1388	LysM domain
DOU34_RS08850	COG3584	3D domain protein
DOU34_RS08855	COG0514	ATP-dependent DNA helicase (RecQ)
DOU34_RS08865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOU34_RS08870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DOU34_RS08885	COG0071	Belongs to the small heat shock protein (HSP20) family
DOU34_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS08920	COG1657	PFAM Prenyltransferase squalene oxidase
DOU34_RS08925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOU34_RS08930	COG0733	neurotransmitter:sodium symporter activity
DOU34_RS08935	COG0385	Bile acid
DOU34_RS08940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS08945	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOU34_RS08955	COG4548	von Willebrand factor, type A
DOU34_RS08960	COG0714	Associated with various cellular activities
DOU34_RS08970	COG0791	NLP P60 protein
DOU34_RS08970	COG1388	LysM domain
DOU34_RS08975	COG1819	glycosyl
DOU34_RS08980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOU34_RS08985	COG0534	Mate efflux family protein
DOU34_RS08990	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS08995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DOU34_RS09000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DOU34_RS09010	COG2962	Rard protein
DOU34_RS09025	COG1942	4-Oxalocrotonate Tautomerase
DOU34_RS09035	COG1733	regulation of RNA biosynthetic process
DOU34_RS09040	COG0778	Nitroreductase
DOU34_RS09045	COG0400	carboxylic ester hydrolase activity
DOU34_RS09050	COG0346	lactoylglutathione lyase activity
DOU34_RS09060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOU34_RS09070	COG2723	6-phospho-beta-galactosidase activity
DOU34_RS09075	COG2188	Transcriptional regulator
DOU34_RS09080	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS09080	COG0793	Belongs to the peptidase S41A family
DOU34_RS09085	COG2226	methyltransferase
DOU34_RS09095	COG1876	peptidase activity
DOU34_RS09115	COG0671	phosphoesterase, PA-phosphatase related
DOU34_RS09145	COG1509	lysine 2,3-aminomutase activity
DOU34_RS09150	COG0456	acetyltransferase
DOU34_RS09155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOU34_RS09160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DOU34_RS09165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOU34_RS09170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DOU34_RS09185	COG0456	acetyltransferase
DOU34_RS09190	COG0463	Glycosyl transferase, family 2
DOU34_RS09205	COG4641	Protein conserved in bacteria
DOU34_RS09215	COG1086	Polysaccharide biosynthesis protein
DOU34_RS09230	COG1846	Transcriptional regulator
DOU34_RS09235	COG4698	Protein conserved in bacteria
DOU34_RS09240	COG2755	lipolytic protein G-D-S-L family
DOU34_RS09245	COG1999	signal sequence binding
DOU34_RS09255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DOU34_RS09260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DOU34_RS09265	COG1272	protein, Hemolysin III
DOU34_RS09270	COG0204	Acyl-transferase
DOU34_RS09275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOU34_RS09290	COG2521	methyltransferase
DOU34_RS09290	COG2136	Putative SAM-dependent methyltransferase
DOU34_RS09305	COG1413	lyase activity
DOU34_RS09310	COG1418	mRNA catabolic process
DOU34_RS09315	COG0386	Belongs to the glutathione peroxidase family
DOU34_RS09325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOU34_RS09330	COG1278	Cold shock
DOU34_RS09350	COG0328	RNA-DNA hybrid ribonuclease activity
DOU34_RS09355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DOU34_RS09360	COG0328	RNA-DNA hybrid ribonuclease activity
DOU34_RS09370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOU34_RS09385	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DOU34_RS09395	COG1755	Isoprenylcysteine carboxyl methyltransferase
DOU34_RS09400	COG3424	synthase
DOU34_RS09425	COG1335	isochorismatase
DOU34_RS09435	COG2233	PERMEase
DOU34_RS09445	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DOU34_RS09450	COG1199	ATP-dependent helicase activity
DOU34_RS09465	COG0116	Belongs to the methyltransferase superfamily
DOU34_RS09490	COG3359	exonuclease
DOU34_RS09495	COG1111	helicase
DOU34_RS09495	COG1205	dead DEAH box helicase
DOU34_RS09500	COG2190	(PTS) system
DOU34_RS09505	COG0071	Belongs to the small heat shock protein (HSP20) family
DOU34_RS09545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOU34_RS09545	COG4499	WXG100 protein secretion system (Wss), protein YukC
DOU34_RS09555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOU34_RS09560	COG3935	DnaD domain protein
DOU34_RS09570	COG0436	Aminotransferase
DOU34_RS09575	COG5353	protein conserved in bacteria
DOU34_RS09585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DOU34_RS09585	COG1199	ATP-dependent helicase activity
DOU34_RS09615	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS09620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DOU34_RS09635	COG1694	Mazg nucleotide pyrophosphohydrolase
DOU34_RS09640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS09645	COG2140	Oxalate decarboxylase
DOU34_RS09655	COG4347	Protein of unknown function (DUF1405)
DOU34_RS09660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DOU34_RS09660	COG2010	Cytochrome c
DOU34_RS09665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DOU34_RS09670	COG0723	plastoquinol--plastocyanin reductase activity
DOU34_RS09685	COG0457	Tetratricopeptide repeat
DOU34_RS09695	COG0287	Prephenate dehydrogenase
DOU34_RS09730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOU34_RS09735	COG4401	Chorismate mutase type I
DOU34_RS09750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DOU34_RS09755	COG0105	UTP biosynthetic process
DOU34_RS09760	COG0142	geranyltranstransferase activity
DOU34_RS09770	COG0142	geranyltranstransferase activity
DOU34_RS09785	COG0776	regulation of translation
DOU34_RS09790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DOU34_RS09830	COG0539	negative regulation of cytoplasmic translation
DOU34_RS09840	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DOU34_RS09845	COG2959	enzyme of heme biosynthesis
DOU34_RS09850	COG3773	Cell wall hydrolase
DOU34_RS09850	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS09860	COG0492	ferredoxin-NADP+ reductase activity
DOU34_RS09865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOU34_RS09870	COG4862	establishment of competence for transformation
DOU34_RS09875	COG1408	metallophosphoesterase
DOU34_RS09885	COG1388	LysM domain
DOU34_RS09890	COG1266	CAAX protease self-immunity
DOU34_RS09895	COG0514	ATP-dependent DNA helicase (RecQ)
DOU34_RS09900	COG4955	Helix-turn-helix domain
DOU34_RS09905	COG1141	Ferredoxin
DOU34_RS09910	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOU34_RS09915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DOU34_RS09925	COG1595	DNA-templated transcription, initiation
DOU34_RS09930	COG5002	protein histidine kinase activity
DOU34_RS09935	COG0745	RESPONSE REGULATOR receiver
DOU34_RS09940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DOU34_RS09945	COG1333	cytochrome c biogenesis protein
DOU34_RS09950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS09955	COG1187	pseudouridine synthase activity
DOU34_RS09960	COG0700	Nucleoside recognition
DOU34_RS09965	COG2715	membrane protein required for spore maturation
DOU34_RS09970	COG1686	Belongs to the peptidase S11 family
DOU34_RS09995	COG1547	Domain of unknown function (DUF309)
DOU34_RS10005	COG0456	acetyltransferase
DOU34_RS10020	COG0307	riboflavin synthase, alpha
DOU34_RS10025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOU34_RS10025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOU34_RS10035	COG0681	Belongs to the peptidase S26 family
DOU34_RS10045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOU34_RS10050	COG4086	secreted protein
DOU34_RS10055	COG0019	diaminopimelate decarboxylase activity
DOU34_RS10060	COG0697	spore germination
DOU34_RS10095	COG1191	sigma factor activity
DOU34_RS10105	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS10110	COG1686	Belongs to the peptidase S11 family
DOU34_RS10115	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DOU34_RS10120	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOU34_RS10125	COG4974	Belongs to the 'phage' integrase family
DOU34_RS10135	COG0735	belongs to the Fur family
DOU34_RS10140	COG1300	Membrane
DOU34_RS10155	COG0281	malic enzyme
DOU34_RS10160	COG1757	Na H antiporter
DOU34_RS10165	COG1027	Aspartate ammonia-lyase
DOU34_RS10170	COG0252	asparaginase activity
DOU34_RS10175	COG1396	sequence-specific DNA binding
DOU34_RS10180	COG1379	DNA repair
DOU34_RS10185	COG0494	nUDIX hydrolase
DOU34_RS10195	COG0667	Aldo Keto reductase
DOU34_RS10205	COG1073	alpha beta
DOU34_RS10215	COG4918	Iron-sulphur cluster biosynthesis
DOU34_RS10220	COG0456	acetyltransferase
DOU34_RS10220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOU34_RS10225	COG2329	Antibiotic biosynthesis monooxygenase
DOU34_RS10230	COG0456	acetyltransferase
DOU34_RS10235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOU34_RS10250	COG0628	permease
DOU34_RS10260	COG0346	lactoylglutathione lyase activity
DOU34_RS10270	COG3048	D-serine ammonia-lyase activity
DOU34_RS10275	COG0300	oxidoreductase activity
DOU34_RS10280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS10285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOU34_RS10290	COG1024	Enoyl-CoA hydratase
DOU34_RS10295	COG3425	synthase
DOU34_RS10305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS10305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS10305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10305	COG3321	synthase
DOU34_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10310	COG3321	synthase
DOU34_RS10310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS10310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS10315	COG0300	oxidoreductase activity
DOU34_RS10315	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS10315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10315	COG3321	synthase
DOU34_RS10320	COG0300	oxidoreductase activity
DOU34_RS10320	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS10320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10320	COG3321	synthase
DOU34_RS10325	COG3321	synthase
DOU34_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS10325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS10330	COG0300	oxidoreductase activity
DOU34_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10330	COG3321	synthase
DOU34_RS10330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10330	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS10335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOU34_RS10335	COG3321	synthase
DOU34_RS10335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS10335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS10335	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS10345	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS10360	COG2070	2-Nitropropane dioxygenase
DOU34_RS10360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DOU34_RS10370	COG0250	Participates in transcription elongation, termination and antitermination
DOU34_RS10395	COG0596	Alpha beta hydrolase
DOU34_RS10410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOU34_RS10415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOU34_RS10430	COG0706	membrane insertase activity
DOU34_RS10435	COG2195	Cleaves the N-terminal amino acid of tripeptides
DOU34_RS10440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DOU34_RS10445	COG0346	lactoylglutathione lyase activity
DOU34_RS10450	COG1376	ErfK ybiS ycfS ynhG family protein
DOU34_RS10455	COG4129	membrane
DOU34_RS10460	COG1126	abc transporter atp-binding protein
DOU34_RS10465	COG0765	amino acid transport
DOU34_RS10470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS10480	COG1597	lipid kinase activity
DOU34_RS10485	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOU34_RS10490	COG0022	dehydrogenase e1 component
DOU34_RS10495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DOU34_RS10500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOU34_RS10505	COG3426	butyrate kinase activity
DOU34_RS10510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOU34_RS10515	COG0280	phosphate acetyltransferase
DOU34_RS10520	COG3829	transcription factor binding
DOU34_RS10520	COG3290	protein histidine kinase activity
DOU34_RS10530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DOU34_RS10535	COG2079	MmgE PrpD family protein
DOU34_RS10545	COG1960	acyl-CoA dehydrogenase activity
DOU34_RS10550	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOU34_RS10555	COG0183	Belongs to the thiolase family
DOU34_RS10560	COG0584	glycerophosphoryl diester phosphodiesterase
DOU34_RS10565	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS10585	COG1902	pentaerythritol trinitrate reductase activity
DOU34_RS10600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOU34_RS10610	COG0745	RESPONSE REGULATOR receiver
DOU34_RS10615	COG0750	zinc metalloprotease
DOU34_RS10620	COG0497	DNA recombination
DOU34_RS10630	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DOU34_RS10640	COG0142	geranyltranstransferase activity
DOU34_RS10650	COG1570	exodeoxyribonuclease VII activity
DOU34_RS10665	COG1302	Protein conserved in bacteria
DOU34_RS10670	COG0439	Biotin carboxylase
DOU34_RS10675	COG0511	ligase activity, forming carbon-carbon bonds
DOU34_RS10715	COG3854	ATPases associated with a variety of cellular activities
DOU34_RS10730	COG0006	proline dipeptidase activity
DOU34_RS10740	COG3872	metal-dependent enzyme
DOU34_RS10750	COG1752	Esterase of the alpha-beta hydrolase superfamily
DOU34_RS10765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOU34_RS10785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DOU34_RS10800	COG1396	sequence-specific DNA binding
DOU34_RS10810	COG0681	Belongs to the peptidase S26 family
DOU34_RS10835	COG4940	Competence protein ComGF
DOU34_RS10845	COG4970	Tfp pilus assembly protein FimT
DOU34_RS10850	COG4537	Required for transformation and DNA binding
DOU34_RS10855	COG1459	type II secretion system
DOU34_RS10860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOU34_RS10865	COG0598	Magnesium transport protein CorA
DOU34_RS10870	COG1253	flavin adenine dinucleotide binding
DOU34_RS10875	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS10885	COG1393	Belongs to the ArsC family
DOU34_RS10895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS10905	COG0011	TIGRFAM Protein of
DOU34_RS10915	COG2866	Carboxypeptidase
DOU34_RS10920	COG1940	carbohydrate kinase activity
DOU34_RS10925	COG4483	Protein conserved in bacteria
DOU34_RS10930	COG1757	Na H antiporter
DOU34_RS10940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOU34_RS10955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOU34_RS10960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOU34_RS10965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOU34_RS10970	COG0581	inorganic phosphate transmembrane transporter activity
DOU34_RS10975	COG0573	inorganic phosphate transmembrane transporter activity
DOU34_RS10980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DOU34_RS10985	COG0768	penicillin binding
DOU34_RS10990	COG0477	Major facilitator Superfamily
DOU34_RS10995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOU34_RS11000	COG2839	Protein conserved in bacteria
DOU34_RS11005	COG5521	maltodextrose utilization protein MalA
DOU34_RS11010	COG1388	LysM domain
DOU34_RS11020	COG4709	membrane
DOU34_RS11025	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DOU34_RS11030	COG0735	belongs to the Fur family
DOU34_RS11035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS11050	COG0513	Belongs to the DEAD box helicase family
DOU34_RS11065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOU34_RS11070	COG2384	SAM-dependent methyltransferase
DOU34_RS11075	COG2010	Cytochrome c
DOU34_RS11080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOU34_RS11085	COG0358	DNA primase activity
DOU34_RS11100	COG0517	IMP dehydrogenase activity
DOU34_RS11105	COG0751	glycine-tRNA ligase activity
DOU34_RS11125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOU34_RS11130	COG0295	cytidine deaminase activity
DOU34_RS11135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DOU34_RS11145	COG1480	7TM receptor with intracellular HD hydrolase
DOU34_RS11150	COG1702	phosphate starvation-inducible protein PhoH
DOU34_RS11155	COG0561	phosphatase activity
DOU34_RS11170	COG4864	UPF0365 protein
DOU34_RS11175	COG1030	water channel activity
DOU34_RS11180	COG1610	YqeY-like protein
DOU34_RS11190	COG1283	sodium-dependent phosphate transmembrane transporter activity
DOU34_RS11195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOU34_RS11200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DOU34_RS11230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOU34_RS11245	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS11260	COG1466	dna polymerase III delta subunit
DOU34_RS11270	COG0658	competence protein
DOU34_RS11270	COG2333	competence protein COMEC
DOU34_RS11275	COG2131	deaminase
DOU34_RS11280	COG1596	polysaccharide export
DOU34_RS11280	COG1555	photosystem II stabilization
DOU34_RS11285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOU34_RS11290	COG2226	methyltransferase
DOU34_RS11295	COG0799	negative regulation of ribosome biogenesis
DOU34_RS11300	COG1713	HD superfamily hydrolase involved in NAD metabolism
DOU34_RS11310	COG1534	Rna-binding protein
DOU34_RS11315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOU34_RS11320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOU34_RS11325	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DOU34_RS11335	COG2755	lipolytic protein G-D-S-L family
DOU34_RS11345	COG0398	Pfam SNARE associated Golgi protein
DOU34_RS11380	COG2207	Transcriptional regulator
DOU34_RS11380	COG3708	Transcriptional regulator
DOU34_RS11390	COG0563	adenylate kinase activity
DOU34_RS11395	COG2814	Major facilitator Superfamily
DOU34_RS11405	COG0456	acetyltransferase
DOU34_RS11410	COG2318	DinB family
DOU34_RS11420	COG0561	phosphatase activity
DOU34_RS11425	COG0561	phosphatase activity
DOU34_RS11435	COG1482	cell wall glycoprotein biosynthetic process
DOU34_RS11440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOU34_RS11440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOU34_RS11440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS11445	COG3711	transcriptional antiterminator
DOU34_RS11445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS11455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOU34_RS11460	COG0583	DNA-binding transcription factor activity
DOU34_RS11465	COG2814	Major facilitator Superfamily
DOU34_RS11470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOU34_RS11470	COG2124	cytochrome p450
DOU34_RS11475	COG1309	transcriptional regulator
DOU34_RS11480	COG2226	methyltransferase
DOU34_RS11495	COG2116	formate transmembrane transporter activity
DOU34_RS11500	COG5609	conserved protein (DUF2294)
DOU34_RS11505	COG3383	formate dehydrogenase (NAD+) activity
DOU34_RS11510	COG2427	Protein of unknown function (DUF1641)
DOU34_RS11520	COG0626	cystathionine gamma-synthase activity
DOU34_RS11525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DOU34_RS11550	COG0768	penicillin binding
DOU34_RS11565	COG0826	peptidase U32
DOU34_RS11570	COG0826	peptidase U32
DOU34_RS11575	COG4122	O-methyltransferase activity
DOU34_RS11580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOU34_RS11595	COG4472	Bacterial protein of unknown function (DUF965)
DOU34_RS11605	COG0628	permease
DOU34_RS11610	COG1126	abc transporter atp-binding protein
DOU34_RS11615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS11620	COG0765	amino acid transport
DOU34_RS11625	COG0765	amino acid transport
DOU34_RS11640	COG3881	PFAM PRC-barrel domain
DOU34_RS11645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DOU34_RS11650	COG0457	Tetratricopeptide repeat
DOU34_RS11660	COG1104	cysteine desulfurase activity
DOU34_RS11665	COG1959	2 iron, 2 sulfur cluster binding
DOU34_RS11670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DOU34_RS11675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DOU34_RS11695	COG3103	Sh3 type 3 domain protein
DOU34_RS11695	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS11695	COG4991	sh3 domain protein
DOU34_RS11705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOU34_RS11715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DOU34_RS11715	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DOU34_RS11720	COG5416	Lipopolysaccharide assembly protein A domain
DOU34_RS11725	COG0490	domain, Protein
DOU34_RS11730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOU34_RS11730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOU34_RS11745	COG2323	membrane
DOU34_RS11755	COG1862	Preprotein translocase
DOU34_RS11800	COG1388	LysM domain
DOU34_RS11810	COG0157	Belongs to the NadC ModD family
DOU34_RS11815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DOU34_RS11820	COG1104	cysteine desulfurase activity
DOU34_RS11825	COG1827	regulation of RNA biosynthetic process
DOU34_RS11830	COG0077	Prephenate dehydratase
DOU34_RS11845	COG3290	protein histidine kinase activity
DOU34_RS11850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DOU34_RS11855	COG2868	ribosomal protein
DOU34_RS11865	COG1994	Peptidase M50
DOU34_RS11870	COG0739	heme binding
DOU34_RS11875	COG2894	cell division
DOU34_RS11885	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DOU34_RS11895	COG1077	Cell shape determining protein MreB Mrl
DOU34_RS11915	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DOU34_RS11920	COG0285	dihydrofolate synthase activity
DOU34_RS11925	COG0525	valine-tRNA ligase activity
DOU34_RS11935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DOU34_RS11940	COG1388	LysM domain
DOU34_RS11950	COG0113	porphobilinogen synthase activity
DOU34_RS11955	COG1587	Uroporphyrinogen-III synthase
DOU34_RS11965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DOU34_RS11985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DOU34_RS11990	COG1067	ATP-dependent peptidase activity
DOU34_RS11990	COG0470	DNA polymerase III
DOU34_RS12000	COG0544	peptidyl-prolyl cis-trans isomerase activity
DOU34_RS12005	COG0457	Tetratricopeptide repeat
DOU34_RS12005	COG1477	protein flavinylation
DOU34_RS12020	COG0473	3-isopropylmalate dehydrogenase activity
DOU34_RS12035	COG0440	acetolactate synthase activity
DOU34_RS12040	COG0028	Belongs to the TPP enzyme family
DOU34_RS12065	COG0622	Phosphoesterase
DOU34_RS12070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOU34_RS12080	COG5401	PFAM Sporulation and spore germination
DOU34_RS12090	COG1846	Transcriptional regulator
DOU34_RS12095	COG2197	response regulator
DOU34_RS12100	COG0824	Thioesterase
DOU34_RS12105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DOU34_RS12110	COG1053	succinate dehydrogenase
DOU34_RS12115	COG2009	succinate dehydrogenase
DOU34_RS12120	COG1719	4-vinyl reductase, 4VR
DOU34_RS12125	COG0527	aspartate kinase activity
DOU34_RS12140	COG3118	belongs to the thioredoxin family
DOU34_RS12145	COG3534	alpha-L-arabinofuranosidase
DOU34_RS12150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DOU34_RS12155	COG2086	electron transfer activity
DOU34_RS12160	COG1024	Enoyl-CoA hydratase
DOU34_RS12165	COG1309	transcriptional regulator
DOU34_RS12170	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS12180	COG3766	membrane
DOU34_RS12190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DOU34_RS12190	COG1796	DNA polymerase
DOU34_RS12195	COG1286	toxin biosynthetic process
DOU34_RS12210	COG0072	phenylalanine-tRNA ligase activity
DOU34_RS12210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOU34_RS12215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOU34_RS12220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOU34_RS12230	COG3835	regulator
DOU34_RS12235	COG0277	FAD linked oxidase domain protein
DOU34_RS12240	COG0247	lactate metabolic process
DOU34_RS12245	COG1966	Carbon starvation protein
DOU34_RS12250	COG3534	alpha-L-arabinofuranosidase
DOU34_RS12255	COG0395	ABC-type sugar transport system, permease component
DOU34_RS12260	COG1175	transmembrane transport
DOU34_RS12265	COG1653	transport
DOU34_RS12275	COG0647	UMP catabolic process
DOU34_RS12280	COG0235	Class ii aldolase
DOU34_RS12285	COG1069	ribulokinase activity
DOU34_RS12290	COG2160	L-arabinose isomerase activity
DOU34_RS12295	COG3507	Belongs to the glycosyl hydrolase 43 family
DOU34_RS12300	COG1363	Peptidase, m42
DOU34_RS12310	COG3326	Membrane
DOU34_RS12315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOU34_RS12325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOU34_RS12330	COG1346	cytolysis
DOU34_RS12335	COG1380	Effector of murein hydrolase LrgA
DOU34_RS12340	COG3279	Response regulator of the LytR AlgR family
DOU34_RS12345	COG3275	phosphorelay sensor kinase activity
DOU34_RS12350	COG1011	Hydrolase
DOU34_RS12365	COG0398	Pfam SNARE associated Golgi protein
DOU34_RS12370	COG1484	DNA-dependent DNA replication
DOU34_RS12375	COG3611	Membrane attachment protein
DOU34_RS12390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DOU34_RS12395	COG1733	regulation of RNA biosynthetic process
DOU34_RS12400	COG2814	Major facilitator Superfamily
DOU34_RS12405	COG0656	L-ascorbic acid biosynthetic process
DOU34_RS12410	COG0237	dephospho-CoA kinase activity
DOU34_RS12415	COG1971	Probably functions as a manganese efflux pump
DOU34_RS12420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DOU34_RS12425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOU34_RS12425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOU34_RS12430	COG5002	protein histidine kinase activity
DOU34_RS12435	COG0745	RESPONSE REGULATOR receiver
DOU34_RS12445	COG0538	isocitrate dehydrogenase activity
DOU34_RS12450	COG0372	Belongs to the citrate synthase family
DOU34_RS12475	COG0628	permease
DOU34_RS12480	COG3030	protein affecting phage T7 exclusion by the F plasmid
DOU34_RS12485	COG0469	pyruvate kinase activity
DOU34_RS12505	COG0281	malic enzyme
DOU34_RS12510	COG0587	DNA-directed DNA polymerase activity
DOU34_RS12530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DOU34_RS12540	COG4109	DRTGG domain
DOU34_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS12565	COG0521	Mo-molybdopterin cofactor biosynthetic process
DOU34_RS12575	COG0827	DNA restriction-modification system
DOU34_RS12580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOU34_RS12585	COG3874	Sporulation protein YtfJ
DOU34_RS12595	COG1714	RDD family
DOU34_RS12600	COG0616	signal peptide processing
DOU34_RS12605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOU34_RS12610	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DOU34_RS12615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOU34_RS12630	COG1104	cysteine desulfurase activity
DOU34_RS12635	COG1114	Component of the transport system for branched-chain amino acids
DOU34_RS12645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DOU34_RS12650	COG1309	transcriptional regulator
DOU34_RS12655	COG1956	GAF domain-containing protein
DOU34_RS12660	COG2203	Gaf domain
DOU34_RS12660	COG2199	diguanylate cyclase activity
DOU34_RS12675	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS12715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOU34_RS12715	COG1017	nitric oxide dioxygenase activity
DOU34_RS12730	COG0693	protein deglycase activity
DOU34_RS12745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOU34_RS12750	COG1378	Sugar-specific transcriptional regulator TrmB
DOU34_RS12775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOU34_RS12780	COG0454	-acetyltransferase
DOU34_RS12785	COG0517	IMP dehydrogenase activity
DOU34_RS12790	COG0123	including yeast histone deacetylase and acetoin utilization protein
DOU34_RS12795	COG1360	Flagellar Motor Protein
DOU34_RS12800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DOU34_RS12805	COG1609	Transcriptional regulator
DOU34_RS12810	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DOU34_RS12810	COG1605	Chorismate mutase
DOU34_RS12815	COG3118	belongs to the thioredoxin family
DOU34_RS12820	COG4980	gas vesicle protein
DOU34_RS12825	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOU34_RS12835	COG1674	ftsk spoiiie
DOU34_RS12840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOU34_RS12850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS12860	COG1363	Peptidase, m42
DOU34_RS12865	COG5584	Small secreted protein
DOU34_RS12870	COG0281	malic enzyme
DOU34_RS12875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOU34_RS12890	COG0510	thiamine kinase activity
DOU34_RS12895	COG1597	lipid kinase activity
DOU34_RS12905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DOU34_RS12910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DOU34_RS12915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOU34_RS12920	COG2252	PERMEase
DOU34_RS12925	COG4473	ABC transporter
DOU34_RS12930	COG1131	(ABC) transporter
DOU34_RS12935	COG1349	DNA-binding transcription factor activity
DOU34_RS12940	COG1187	pseudouridine synthase activity
DOU34_RS12945	COG2244	polysaccharide biosynthetic process
DOU34_RS12950	COG2081	HI0933 family
DOU34_RS12955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DOU34_RS12965	COG1609	Transcriptional regulator
DOU34_RS12970	COG1653	transport
DOU34_RS12975	COG1175	transmembrane transport
DOU34_RS12980	COG0395	ABC-type sugar transport system, permease component
DOU34_RS12985	COG1486	melibiose metabolic process
DOU34_RS12995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOU34_RS13010	COG2202	Pas domain
DOU34_RS13010	COG1366	Belongs to the anti-sigma-factor antagonist family
DOU34_RS13020	COG2814	Major facilitator Superfamily
DOU34_RS13025	COG5522	Integral membrane protein (intg_mem_TP0381)
DOU34_RS13030	COG0577	efflux transmembrane transporter activity
DOU34_RS13035	COG1136	(ABC) transporter
DOU34_RS13040	COG2205	protein histidine kinase activity
DOU34_RS13045	COG0745	RESPONSE REGULATOR receiver
DOU34_RS13050	COG0577	efflux transmembrane transporter activity
DOU34_RS13055	COG1136	(ABC) transporter
DOU34_RS13075	COG1131	(ABC) transporter
DOU34_RS13080	COG1725	Transcriptional regulator
DOU34_RS13090	COG0640	Transcriptional regulator
DOU34_RS13095	COG0477	Major facilitator Superfamily
DOU34_RS13100	COG1242	4 iron, 4 sulfur cluster binding
DOU34_RS13105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DOU34_RS13115	COG0584	glycerophosphoryl diester phosphodiesterase
DOU34_RS13125	COG2267	carboxylic ester hydrolase activity
DOU34_RS13130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DOU34_RS13135	COG1113	amino acid transport
DOU34_RS13140	COG0367	asparagine synthase
DOU34_RS13160	COG1506	peptidase
DOU34_RS13165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DOU34_RS13170	COG1116	anion transmembrane transporter activity
DOU34_RS13175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOU34_RS13180	COG0494	nUDIX hydrolase
DOU34_RS13185	COG4824	toxin secretion phage lysis holin
DOU34_RS13190	COG0783	Belongs to the Dps family
DOU34_RS13215	COG0288	reversible hydration of carbon dioxide
DOU34_RS13225	COG1271	oxidase subunit
DOU34_RS13230	COG1294	oxidase, subunit
DOU34_RS13245	COG4948	Mandelate Racemase Muconate Lactonizing
DOU34_RS13255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOU34_RS13260	COG0596	Alpha beta hydrolase
DOU34_RS13270	COG1169	isochorismate synthase
DOU34_RS13275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DOU34_RS13280	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DOU34_RS13405	COG3859	Proton-coupled thiamine transporter YuaJ
DOU34_RS13410	COG2268	Band 7 protein
DOU34_RS13415	COG1585	Membrane protein implicated in regulation of membrane protease activity
DOU34_RS13420	COG2318	DinB family
DOU34_RS13430	COG1454	alcohol dehydrogenase
DOU34_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS13440	COG1510	regulation of RNA biosynthetic process
DOU34_RS13450	COG0569	domain protein
DOU34_RS13455	COG1705	Flagellar rod assembly protein muramidase FlgJ
DOU34_RS13460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DOU34_RS13460	COG1017	nitric oxide dioxygenase activity
DOU34_RS13485	COG0628	permease
DOU34_RS13490	COG0673	inositol 2-dehydrogenase activity
DOU34_RS13495	COG0693	protein deglycase activity
DOU34_RS13500	COG0840	transmembrane signaling receptor activity
DOU34_RS13505	COG0840	transmembrane signaling receptor activity
DOU34_RS13510	COG0840	transmembrane signaling receptor activity
DOU34_RS13515	COG0840	transmembrane signaling receptor activity
DOU34_RS13530	COG2070	2-Nitropropane dioxygenase
DOU34_RS13535	COG0432	Pfam Uncharacterised protein family UPF0047
DOU34_RS13540	COG0366	Alpha amylase catalytic
DOU34_RS13545	COG1253	flavin adenine dinucleotide binding
DOU34_RS13550	COG2738	Putative neutral zinc metallopeptidase
DOU34_RS13565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DOU34_RS13595	COG1335	isochorismatase
DOU34_RS13600	COG1979	alcohol dehydrogenase
DOU34_RS13605	COG1979	alcohol dehydrogenase
DOU34_RS13610	COG2155	Conserved Protein
DOU34_RS13615	COG1098	S1 RNA binding domain
DOU34_RS13620	COG0436	Aminotransferase
DOU34_RS13625	COG1522	sequence-specific DNA binding
DOU34_RS13630	COG2267	carboxylic ester hydrolase activity
DOU34_RS13640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DOU34_RS13645	COG2205	protein histidine kinase activity
DOU34_RS13655	COG5018	Exonuclease
DOU34_RS13660	COG2814	Major facilitator Superfamily
DOU34_RS13665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOU34_RS13670	COG3011	Protein conserved in bacteria
DOU34_RS13680	COG3290	protein histidine kinase activity
DOU34_RS13685	COG4565	transcriptional regulatory protein
DOU34_RS13690	COG1744	ABC transporter substrate-binding protein PnrA-like
DOU34_RS13695	COG3845	ABC transporter
DOU34_RS13700	COG4603	Belongs to the binding-protein-dependent transport system permease family
DOU34_RS13705	COG1079	Belongs to the binding-protein-dependent transport system permease family
DOU34_RS13715	COG2111	Na H antiporter
DOU34_RS13715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOU34_RS13720	COG2111	Na H antiporter
DOU34_RS13725	COG1006	Multisubunit Na H antiporter MnhC subunit
DOU34_RS13730	COG0651	ATP synthesis coupled electron transport
DOU34_RS13735	COG1863	multisubunit Na H antiporter MnhE subunit
DOU34_RS13740	COG2212	antiporter activity
DOU34_RS13745	COG1320	monovalent cation:proton antiporter activity
DOU34_RS13750	COG2050	protein possibly involved in aromatic compounds catabolism
DOU34_RS13755	COG2197	response regulator
DOU34_RS13760	COG4585	Histidine kinase
DOU34_RS13770	COG0142	geranyltranstransferase activity
DOU34_RS13790	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DOU34_RS13795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOU34_RS13800	COG1335	isochorismatase
DOU34_RS13805	COG5506	Protein of unknown function (DUF1694)
DOU34_RS13820	COG0628	permease
DOU34_RS13830	COG1418	mRNA catabolic process
DOU34_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS13845	COG1511	domain protein
DOU34_RS13850	COG1674	ftsk spoiiie
DOU34_RS13850	COG0433	COG0433 Predicted ATPase
DOU34_RS13855	COG4499	WXG100 protein secretion system (Wss), protein YukC
DOU34_RS13860	COG5417	Belongs to the EsaB family
DOU34_RS13865	COG4842	Belongs to the WXG100 family
DOU34_RS13870	COG2508	Transcriptional regulator
DOU34_RS13870	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DOU34_RS13875	COG0686	Belongs to the AlaDH PNT family
DOU34_RS13880	COG5634	Uncharacterized conserved protein (DUF2278)
DOU34_RS13885	COG3251	PFAM MbtH domain protein
DOU34_RS13890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS13895	COG3433	isochorismatase activity
DOU34_RS13895	COG1535	isochorismatase
DOU34_RS13900	COG1021	2,3-dihydroxybenzoate-AMP ligase
DOU34_RS13905	COG1169	isochorismate synthase
DOU34_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS13915	COG2819	hydrolase of the alpha beta superfamily
DOU34_RS13920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DOU34_RS13925	COG1268	BioY protein
DOU34_RS13930	COG2056	Na+-H+ antiporter family
DOU34_RS13940	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DOU34_RS13945	COG3584	3D domain protein
DOU34_RS13960	COG1252	NADH dehydrogenase
DOU34_RS13990	COG1131	(ABC) transporter
DOU34_RS14010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS14015	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DOU34_RS14020	COG0316	Belongs to the HesB IscA family
DOU34_RS14030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOU34_RS14040	COG1252	NADH dehydrogenase
DOU34_RS14045	COG4837	Protein of unknown function (DUF1462)
DOU34_RS14050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DOU34_RS14055	COG0823	Involved in the tonB-independent uptake of proteins
DOU34_RS14055	COG4946	Tricorn protease homolog
DOU34_RS14055	COG1506	peptidase
DOU34_RS14065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DOU34_RS14070	COG0460	homoserine dehydrogenase
DOU34_RS14075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DOU34_RS14080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DOU34_RS14085	COG0647	UMP catabolic process
DOU34_RS14090	COG2445	Protein of unknown function DUF86
DOU34_RS14095	COG4470	Protein conserved in bacteria
DOU34_RS14110	COG0739	heme binding
DOU34_RS14120	COG0737	Belongs to the 5'-nucleotidase family
DOU34_RS14125	COG0730	response to heat
DOU34_RS14130	COG1801	Protein of unknown function DUF72
DOU34_RS14145	COG2508	Transcriptional regulator
DOU34_RS14170	COG2814	Major facilitator Superfamily
DOU34_RS14175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DOU34_RS14180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOU34_RS14185	COG2356	endonuclease I
DOU34_RS14190	COG3842	ATPase activity
DOU34_RS14195	COG2188	Transcriptional regulator
DOU34_RS14200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOU34_RS14205	COG0395	ABC-type sugar transport system, permease component
DOU34_RS14210	COG1175	transmembrane transport
DOU34_RS14215	COG1653	transport
DOU34_RS14220	COG2222	sugar isomerase
DOU34_RS14225	COG0789	Transcriptional regulator
DOU34_RS14250	COG0322	excinuclease ABC activity
DOU34_RS14255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOU34_RS14260	COG2226	methyltransferase
DOU34_RS14270	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS14275	COG0719	Fe-S assembly protein
DOU34_RS14280	COG0822	iron-sulfur transferase activity
DOU34_RS14285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOU34_RS14290	COG0719	Fe-S assembly protein
DOU34_RS14295	COG0396	ATPase activity
DOU34_RS14305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DOU34_RS14310	COG1464	Belongs to the NlpA lipoprotein family
DOU34_RS14315	COG2011	ABC-type metal ion transport system permease component
DOU34_RS14320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOU34_RS14330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS14335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOU34_RS14350	COG1393	Belongs to the ArsC family
DOU34_RS14355	COG1960	acyl-CoA dehydrogenase activity
DOU34_RS14360	COG0183	Belongs to the thiolase family
DOU34_RS14365	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOU34_RS14365	COG1024	Enoyl-CoA hydratase
DOU34_RS14380	COG0477	Major facilitator Superfamily
DOU34_RS14390	COG5577	PFAM Coat F domain
DOU34_RS14395	COG1846	Transcriptional regulator
DOU34_RS14400	COG0477	Major facilitator Superfamily
DOU34_RS14405	COG0583	DNA-binding transcription factor activity
DOU34_RS14425	COG1120	ATPase activity
DOU34_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS14445	COG0783	Belongs to the Dps family
DOU34_RS14450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOU34_RS14455	COG0745	RESPONSE REGULATOR receiver
DOU34_RS14460	COG2205	protein histidine kinase activity
DOU34_RS14460	COG2770	Histidine kinase
DOU34_RS14470	COG1309	transcriptional regulator
DOU34_RS14475	COG0114	fumarate hydratase activity
DOU34_RS14485	COG0697	spore germination
DOU34_RS14490	COG0814	amino acid
DOU34_RS14500	COG2197	response regulator
DOU34_RS14505	COG4585	Histidine kinase
DOU34_RS14510	COG4758	membrane
DOU34_RS14515	COG3595	metallopeptidase activity
DOU34_RS14520	COG1842	Phage shock protein A
DOU34_RS14525	COG4758	membrane
DOU34_RS14530	COG2814	Major facilitator Superfamily
DOU34_RS14535	COG2096	Adenosyltransferase
DOU34_RS14540	COG1120	ATPase activity
DOU34_RS14545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS14550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DOU34_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS14560	COG3386	PFAM SMP-30 Gluconolaconase
DOU34_RS14565	COG2205	protein histidine kinase activity
DOU34_RS14570	COG0745	RESPONSE REGULATOR receiver
DOU34_RS14580	COG1191	sigma factor activity
DOU34_RS14590	COG2140	Oxalate decarboxylase
DOU34_RS14600	COG1120	ATPase activity
DOU34_RS14605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS14610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS14615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DOU34_RS14620	COG0531	amino acid
DOU34_RS14635	COG1988	membrane-bound metal-dependent
DOU34_RS14640	COG1368	sulfuric ester hydrolase activity
DOU34_RS14645	COG1910	domain protein
DOU34_RS14650	COG0725	ABC transporter, periplasmic molybdate-binding protein
DOU34_RS14655	COG4149	molybdate abc transporter
DOU34_RS14660	COG2197	response regulator
DOU34_RS14665	COG3850	Histidine kinase
DOU34_RS14670	COG1131	(ABC) transporter
DOU34_RS14680	COG0842	Transport permease protein
DOU34_RS14685	COG0656	L-ascorbic acid biosynthetic process
DOU34_RS14710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOU34_RS14715	COG3973	AAA domain
DOU34_RS14720	COG2860	membrane
DOU34_RS14730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DOU34_RS14735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DOU34_RS14740	COG2217	Heavy metal translocating P-type atpase
DOU34_RS14745	COG2217	Heavy metal translocating P-type atpase
DOU34_RS14750	COG2608	mercury ion transmembrane transporter activity
DOU34_RS14755	COG1937	Protein conserved in bacteria
DOU34_RS14760	COG0673	inositol 2-dehydrogenase activity
DOU34_RS14770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS14775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DOU34_RS14780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS14785	COG1126	abc transporter atp-binding protein
DOU34_RS14790	COG0765	amino acid transport
DOU34_RS14795	COG0765	amino acid transport
DOU34_RS14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS14805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DOU34_RS14810	COG0454	-acetyltransferase
DOU34_RS14815	COG0583	DNA-binding transcription factor activity
DOU34_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS14825	COG2732	(Barnase) inhibitor
DOU34_RS14840	COG0557	exoribonuclease II activity
DOU34_RS14845	COG1647	Serine aminopeptidase, S33
DOU34_RS14850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DOU34_RS14855	COG1476	TRANSCRIPTIONal
DOU34_RS14860	COG1396	sequence-specific DNA binding
DOU34_RS14865	COG1396	sequence-specific DNA binding
DOU34_RS14870	COG1733	regulation of RNA biosynthetic process
DOU34_RS14895	COG1131	(ABC) transporter
DOU34_RS14900	COG1174	glycine betaine transport
DOU34_RS14905	COG1732	Glycine betaine
DOU34_RS14910	COG1174	glycine betaine transport
DOU34_RS14915	COG1125	glycine betaine transport
DOU34_RS14915	COG0517	IMP dehydrogenase activity
DOU34_RS14920	COG1510	regulation of RNA biosynthetic process
DOU34_RS14925	COG1174	glycine betaine transport
DOU34_RS14930	COG1732	Glycine betaine
DOU34_RS14935	COG1174	glycine betaine transport
DOU34_RS14940	COG1125	glycine betaine transport
DOU34_RS14940	COG0517	IMP dehydrogenase activity
DOU34_RS14945	COG1510	regulation of RNA biosynthetic process
DOU34_RS14950	COG2095	MarC family integral membrane protein
DOU34_RS14955	COG3064	Membrane
DOU34_RS14960	COG4640	response to antibiotic
DOU34_RS14965	COG0456	acetyltransferase
DOU34_RS14980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DOU34_RS14995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOU34_RS15000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOU34_RS15005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOU34_RS15015	COG2234	aminopeptidase activity
DOU34_RS15035	COG0126	phosphoglycerate kinase activity
DOU34_RS15045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DOU34_RS15050	COG2390	Transcriptional regulator
DOU34_RS15055	COG2814	Major facilitator Superfamily
DOU34_RS15060	COG1609	Transcriptional regulator
DOU34_RS15065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS15075	COG0583	DNA-binding transcription factor activity
DOU34_RS15080	COG0697	spore germination
DOU34_RS15085	COG1113	amino acid transport
DOU34_RS15095	COG1609	Transcriptional regulator
DOU34_RS15105	COG0561	phosphatase activity
DOU34_RS15110	COG1737	Transcriptional regulator
DOU34_RS15115	COG1070	Carbohydrate kinase
DOU34_RS15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS15185	COG2186	Transcriptional regulator
DOU34_RS15190	COG1620	l-lactate permease
DOU34_RS15195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DOU34_RS15205	COG5039	Polysaccharide pyruvyl transferase
DOU34_RS15210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOU34_RS15215	COG0110	maltose O-acetyltransferase activity
DOU34_RS15220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DOU34_RS15225	COG2244	polysaccharide biosynthetic process
DOU34_RS15230	COG1216	Glycosyl transferase, family 2
DOU34_RS15235	COG5039	Polysaccharide pyruvyl transferase
DOU34_RS15240	COG1216	Glycosyl transferase, family 2
DOU34_RS15250	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS15255	COG1215	transferase activity, transferring glycosyl groups
DOU34_RS15260	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS15265	COG1086	Polysaccharide biosynthesis protein
DOU34_RS15270	COG0489	protein tyrosine kinase activity
DOU34_RS15275	COG3944	biosynthesis protein
DOU34_RS15280	COG1396	sequence-specific DNA binding
DOU34_RS15285	COG2272	Belongs to the type-B carboxylesterase lipase family
DOU34_RS15295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOU34_RS15300	COG2364	Membrane
DOU34_RS15305	COG0456	acetyltransferase
DOU34_RS15310	COG3479	Phenolic acid decarboxylase
DOU34_RS15365	COG2223	nitrite transmembrane transporter activity
DOU34_RS15370	COG1609	Transcriptional regulator
DOU34_RS15380	COG0583	DNA-binding transcription factor activity
DOU34_RS15385	COG2828	Protein conserved in bacteria
DOU34_RS15390	COG2814	Major facilitator Superfamily
DOU34_RS15390	COG0477	Major facilitator Superfamily
DOU34_RS15395	COG1611	Belongs to the LOG family
DOU34_RS15400	COG1694	Mazg nucleotide pyrophosphohydrolase
DOU34_RS15405	COG0659	secondary active sulfate transmembrane transporter activity
DOU34_RS15410	COG0288	reversible hydration of carbon dioxide
DOU34_RS15420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOU34_RS15425	COG4290	ribonuclease
DOU34_RS15430	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DOU34_RS15435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS15445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DOU34_RS15455	COG1051	belongs to the nudix hydrolase family
DOU34_RS15460	COG0492	ferredoxin-NADP+ reductase activity
DOU34_RS15465	COG3883	PFAM NLP P60 protein
DOU34_RS15465	COG0791	NLP P60 protein
DOU34_RS15470	COG0457	Tetratricopeptide repeat
DOU34_RS15475	COG5002	protein histidine kinase activity
DOU34_RS15480	COG0745	RESPONSE REGULATOR receiver
DOU34_RS15485	COG1132	(ABC) transporter
DOU34_RS15490	COG0140	phosphoribosyl-ATP diphosphatase activity
DOU34_RS15490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DOU34_RS15515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOU34_RS15530	COG4990	cell redox homeostasis
DOU34_RS15535	COG0110	maltose O-acetyltransferase activity
DOU34_RS15565	COG2188	Transcriptional regulator
DOU34_RS15570	COG1309	transcriptional regulator
DOU34_RS15575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DOU34_RS15580	COG1950	PFAM Membrane protein of
DOU34_RS15585	COG1983	PspC domain protein
DOU34_RS15590	COG3595	metallopeptidase activity
DOU34_RS15605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DOU34_RS15615	COG4897	Protein conserved in bacteria
DOU34_RS15620	COG3848	Pyruvate phosphate dikinase
DOU34_RS15620	COG0574	Belongs to the PEP-utilizing enzyme family
DOU34_RS15625	COG1309	transcriptional regulator
DOU34_RS15630	COG2814	Major facilitator Superfamily
DOU34_RS15635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOU34_RS15645	COG0793	Belongs to the peptidase S41A family
DOU34_RS15645	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS15650	COG3420	alginic acid biosynthetic process
DOU34_RS15655	COG2177	Part of the ABC transporter FtsEX involved in
DOU34_RS15660	COG2884	Cell division ATP-binding protein ftsE
DOU34_RS15665	COG2010	Cytochrome c
DOU34_RS15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS15685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOU34_RS15700	COG1516	flagellar protein fliS
DOU34_RS15705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DOU34_RS15710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOU34_RS15730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOU34_RS15735	COG1256	bacterial-type flagellum assembly
DOU34_RS15735	COG4786	Flagellar basal body rod
DOU34_RS15740	COG3418	PFAM FlgN family protein
DOU34_RS15745	COG2747	anti-sigma28 factor FlgM
DOU34_RS15755	COG1040	competence protein
DOU34_RS15765	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DOU34_RS15770	COG1307	EDD domain protein, DegV family
DOU34_RS15775	COG2197	response regulator
DOU34_RS15780	COG4585	Histidine kinase
DOU34_RS15785	COG1739	Uncharacterized protein family UPF0029
DOU34_RS15790	COG1316	TRANSCRIPTIONal
DOU34_RS15795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOU34_RS15800	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS15805	COG1215	transferase activity, transferring glycosyl groups
DOU34_RS15810	COG3206	protein involved in exopolysaccharide biosynthesis
DOU34_RS15815	COG3307	-O-antigen
DOU34_RS15820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DOU34_RS15825	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS15825	COG0297	glycogen (starch) synthase activity
DOU34_RS15830	COG2244	polysaccharide biosynthetic process
DOU34_RS15840	COG2247	cell wall binding repeat
DOU34_RS15840	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS15845	COG2385	sporulation resulting in formation of a cellular spore
DOU34_RS15845	COG2247	cell wall binding repeat
DOU34_RS15855	COG1316	TRANSCRIPTIONal
DOU34_RS15860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DOU34_RS15865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DOU34_RS15870	COG1134	teichoic acid transport
DOU34_RS15875	COG1682	transport, permease protein
DOU34_RS15880	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DOU34_RS15890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DOU34_RS15895	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DOU34_RS15900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DOU34_RS15905	COG4193	domain, Protein
DOU34_RS15910	COG1482	cell wall glycoprotein biosynthetic process
DOU34_RS15915	COG0697	spore germination
DOU34_RS15920	COG0814	amino acid
DOU34_RS15930	COG1215	transferase activity, transferring glycosyl groups
DOU34_RS15935	COG2814	Major facilitator Superfamily
DOU34_RS15940	COG1316	TRANSCRIPTIONal
DOU34_RS15945	COG0561	phosphatase activity
DOU34_RS15950	COG2433	Pfam Transposase IS66
DOU34_RS15955	COG0791	NLP P60 protein
DOU34_RS15965	COG2843	Capsule synthesis protein
DOU34_RS15975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOU34_RS15985	COG0697	spore germination
DOU34_RS15990	COG0814	amino acid
DOU34_RS16000	COG1609	Transcriptional regulator
DOU34_RS16005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOU34_RS16015	COG1129	ABC transporter
DOU34_RS16020	COG1172	Belongs to the binding-protein-dependent transport system permease family
DOU34_RS16025	COG1879	ABC-type sugar transport system periplasmic component
DOU34_RS16030	COG3103	Sh3 type 3 domain protein
DOU34_RS16035	COG2249	NAD(P)H dehydrogenase (quinone) activity
DOU34_RS16040	COG3527	Alpha-acetolactate decarboxylase
DOU34_RS16045	COG0028	Belongs to the TPP enzyme family
DOU34_RS16050	COG0583	DNA-binding transcription factor activity
DOU34_RS16055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DOU34_RS16080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOU34_RS16090	COG0405	Gamma-glutamyltransferase
DOU34_RS16095	COG1522	sequence-specific DNA binding
DOU34_RS16100	COG2059	Chromate
DOU34_RS16105	COG2059	Chromate
DOU34_RS16120	COG5444	nuclease activity
DOU34_RS16135	COG3878	Protein conserved in bacteria
DOU34_RS16140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DOU34_RS16145	COG4464	protein tyrosine phosphatase activity
DOU34_RS16150	COG0489	protein tyrosine kinase activity
DOU34_RS16155	COG3944	biosynthesis protein
DOU34_RS16170	COG4715	Zinc finger, swim domain protein
DOU34_RS16175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DOU34_RS16180	COG0561	phosphatase activity
DOU34_RS16185	COG1349	DNA-binding transcription factor activity
DOU34_RS16190	COG0629	single-stranded DNA binding
DOU34_RS16215	COG0457	Tetratricopeptide repeat
DOU34_RS16220	COG4786	Flagellar basal body rod
DOU34_RS16225	COG4786	Flagellar basal body rod
DOU34_RS16230	COG1077	Cell shape determining protein MreB Mrl
DOU34_RS16235	COG1609	Transcriptional regulator
DOU34_RS16240	COG1846	Transcriptional regulator
DOU34_RS16245	COG2814	Major facilitator Superfamily
DOU34_RS16250	COG1953	Uracil, thiamine, allantoin
DOU34_RS16255	COG0477	Major facilitator Superfamily
DOU34_RS16260	COG1335	isochorismatase
DOU34_RS16265	COG0004	ammonium transporteR
DOU34_RS16270	COG0347	Belongs to the P(II) protein family
DOU34_RS16275	COG0772	Belongs to the SEDS family
DOU34_RS16280	COG0671	phosphoesterase, PA-phosphatase related
DOU34_RS16290	COG0739	heme binding
DOU34_RS16295	COG1247	-acetyltransferase
DOU34_RS16310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOU34_RS16325	COG0726	polysaccharide deacetylase
DOU34_RS16330	COG1959	2 iron, 2 sulfur cluster binding
DOU34_RS16345	COG0831	urea catabolic process
DOU34_RS16350	COG3237	CsbD-like
DOU34_RS16355	COG1994	Peptidase M50
DOU34_RS16360	COG0457	Tetratricopeptide repeat
DOU34_RS16370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DOU34_RS16375	COG2304	oxidoreductase activity
DOU34_RS16380	COG2304	oxidoreductase activity
DOU34_RS16390	COG2385	sporulation resulting in formation of a cellular spore
DOU34_RS16395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOU34_RS16405	COG4836	Membrane
DOU34_RS16475	COG0698	ribose 5-phosphate isomerase
DOU34_RS16480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOU34_RS16490	COG0009	L-threonylcarbamoyladenylate synthase
DOU34_RS16495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DOU34_RS16515	COG2890	protein-(glutamine-N5) methyltransferase activity
DOU34_RS16520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOU34_RS16525	COG0346	lactoylglutathione lyase activity
DOU34_RS16530	COG0789	Transcriptional regulator
DOU34_RS16535	COG0679	Auxin Efflux Carrier
DOU34_RS16540	COG0281	malic enzyme
DOU34_RS16555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DOU34_RS16560	COG1494	fructose-1,6-bisphosphatase
DOU34_RS16565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOU34_RS16580	COG0191	fructose-bisphosphate aldolase activity
DOU34_RS16585	COG2204	response regulator
DOU34_RS16590	COG4821	SIS domain
DOU34_RS16605	COG2181	nitrate reductase activity
DOU34_RS16605	COG0247	lactate metabolic process
DOU34_RS16610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOU34_RS16625	COG1132	(ABC) transporter
DOU34_RS16630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOU34_RS16640	COG2181	nitrate reductase activity
DOU34_RS16645	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DOU34_RS16650	COG1140	nitrate reductase beta subunit
DOU34_RS16655	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOU34_RS16660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOU34_RS16670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOU34_RS16675	COG2223	nitrite transmembrane transporter activity
DOU34_RS16685	COG4506	Protein conserved in bacteria
DOU34_RS16695	COG3391	amine dehydrogenase activity
DOU34_RS16700	COG3391	amine dehydrogenase activity
DOU34_RS16710	COG0457	Tetratricopeptide repeat
DOU34_RS16755	COG0010	Belongs to the arginase family
DOU34_RS16760	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DOU34_RS16765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOU34_RS16780	COG1994	Peptidase M50
DOU34_RS16785	COG1942	4-Oxalocrotonate Tautomerase
DOU34_RS16790	COG1846	Transcriptional regulator
DOU34_RS16800	COG0531	amino acid
DOU34_RS16805	COG3465	dGTPase activity
DOU34_RS16810	COG1078	dGTPase activity
DOU34_RS16825	COG1695	Transcriptional regulator
DOU34_RS16835	COG1131	(ABC) transporter
DOU34_RS16840	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DOU34_RS16870	COG0583	DNA-binding transcription factor activity
DOU34_RS16875	COG2855	membrane
DOU34_RS16880	COG0280	phosphate acetyltransferase
DOU34_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS16895	COG0436	Aminotransferase
DOU34_RS16925	COG2814	Major facilitator Superfamily
DOU34_RS16930	COG2814	Major facilitator Superfamily
DOU34_RS16935	COG0833	amino acid
DOU34_RS16940	COG4187	Peptidase family M20/M25/M40
DOU34_RS16945	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS16950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DOU34_RS16960	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DOU34_RS16965	COG1091	dTDP-4-dehydrorhamnose reductase activity
DOU34_RS16970	COG1088	dTDP-glucose 4,6-dehydratase activity
DOU34_RS16975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DOU34_RS16980	COG3980	spore coat polysaccharide biosynthesis protein
DOU34_RS16985	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DOU34_RS16990	COG2089	acid synthase
DOU34_RS16995	COG0456	acetyltransferase
DOU34_RS17000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DOU34_RS17005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DOU34_RS17010	COG0463	Glycosyl transferase, family 2
DOU34_RS17020	COG2363	Small membrane protein
DOU34_RS17025	COG2233	PERMEase
DOU34_RS17040	COG1216	Glycosyl transferase, family 2
DOU34_RS17055	COG1695	Transcriptional regulator
DOU34_RS17060	COG0351	phosphomethylpyrimidine kinase
DOU34_RS17070	COG1621	beta-fructofuranosidase activity
DOU34_RS17075	COG1263	PTS System
DOU34_RS17075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS17080	COG3711	transcriptional antiterminator
DOU34_RS17090	COG1404	Belongs to the peptidase S8 family
DOU34_RS17095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS17100	COG0778	Nitroreductase
DOU34_RS17105	COG0772	Belongs to the SEDS family
DOU34_RS17110	COG0454	-acetyltransferase
DOU34_RS17130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOU34_RS17135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DOU34_RS17140	COG2261	transglycosylase associated protein
DOU34_RS17145	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DOU34_RS17150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOU34_RS17155	COG2246	polysaccharide biosynthetic process
DOU34_RS17160	COG1309	transcriptional regulator
DOU34_RS17180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DOU34_RS17185	COG2837	iron assimilation
DOU34_RS17190	COG2822	iron ion transport
DOU34_RS17205	COG0583	DNA-binding transcription factor activity
DOU34_RS17215	COG1346	cytolysis
DOU34_RS17220	COG1131	(ABC) transporter
DOU34_RS17250	COG4895	conserved protein (DUF2196)
DOU34_RS17260	COG0789	Transcriptional regulator
DOU34_RS17265	COG5504	Zn-dependent protease
DOU34_RS17270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DOU34_RS17275	COG0346	lactoylglutathione lyase activity
DOU34_RS17280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS17285	COG1404	Belongs to the peptidase S8 family
DOU34_RS17290	COG1442	glycosyl transferase family 8
DOU34_RS17295	COG2357	RelA SpoT domain protein
DOU34_RS17300	COG1575	Belongs to the MenA family. Type 1 subfamily
DOU34_RS17320	COG1696	Membrane protein involved in D-alanine export
DOU34_RS17330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOU34_RS17335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS17340	COG1486	melibiose metabolic process
DOU34_RS17345	COG1447	Phosphotransferase system cellobiose-specific component IIA
DOU34_RS17350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS17355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS17360	COG3711	transcriptional antiterminator
DOU34_RS17360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOU34_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS17390	COG0640	Transcriptional regulator
DOU34_RS17395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DOU34_RS17400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS17405	COG1447	Phosphotransferase system cellobiose-specific component IIA
DOU34_RS17410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DOU34_RS17415	COG2723	6-phospho-beta-galactosidase activity
DOU34_RS17420	COG1940	carbohydrate kinase activity
DOU34_RS17425	COG1482	cell wall glycoprotein biosynthetic process
DOU34_RS17435	COG0753	catalase activity
DOU34_RS17445	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DOU34_RS17450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DOU34_RS17455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DOU34_RS17460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DOU34_RS17465	COG4988	ABC transporter
DOU34_RS17470	COG1294	oxidase, subunit
DOU34_RS17475	COG1271	oxidase subunit
DOU34_RS17480	COG3493	citrate carrier protein
DOU34_RS17485	COG0726	polysaccharide deacetylase
DOU34_RS17490	COG3842	ATPase activity
DOU34_RS17495	COG2508	Transcriptional regulator
DOU34_RS17500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS17510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOU34_RS17520	COG4894	glucomannan catabolic process
DOU34_RS17525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOU34_RS17530	COG0500	methyltransferase
DOU34_RS17535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOU34_RS17550	COG0753	catalase activity
DOU34_RS17550	COG0693	protein deglycase activity
DOU34_RS17555	COG2851	Citrate transporter
DOU34_RS17560	COG2273	Hydrolase Family 16
DOU34_RS17565	COG3711	transcriptional antiterminator
DOU34_RS17570	COG2270	Major facilitator Superfamily
DOU34_RS17575	COG0513	Belongs to the DEAD box helicase family
DOU34_RS17610	COG0697	spore germination
DOU34_RS17615	COG0589	response to stress
DOU34_RS17620	COG2723	6-phospho-beta-galactosidase activity
DOU34_RS17625	COG2190	(PTS) system
DOU34_RS17625	COG1263	PTS System
DOU34_RS17625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS17640	COG0494	nUDIX hydrolase
DOU34_RS17645	COG3507	Belongs to the glycosyl hydrolase 43 family
DOU34_RS17670	COG0010	Belongs to the arginase family
DOU34_RS17675	COG0833	amino acid
DOU34_RS17680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DOU34_RS17685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOU34_RS17695	COG2390	Transcriptional regulator
DOU34_RS17700	COG0561	phosphatase activity
DOU34_RS17730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DOU34_RS17735	COG5294	Protein conserved in bacteria
DOU34_RS17740	COG0577	efflux transmembrane transporter activity
DOU34_RS17745	COG1136	(ABC) transporter
DOU34_RS17750	COG2205	protein histidine kinase activity
DOU34_RS17755	COG0745	RESPONSE REGULATOR receiver
DOU34_RS17770	COG1082	Xylose isomerase domain protein TIM barrel
DOU34_RS17780	COG2814	Major facilitator Superfamily
DOU34_RS17810	COG1349	DNA-binding transcription factor activity
DOU34_RS17815	COG0667	Aldo Keto reductase
DOU34_RS17820	COG2814	Major facilitator Superfamily
DOU34_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS17840	COG2197	response regulator
DOU34_RS17845	COG4585	Histidine kinase
DOU34_RS17850	COG3239	Fatty acid desaturase
DOU34_RS17860	COG1309	transcriptional regulator
DOU34_RS17865	COG1012	belongs to the aldehyde dehydrogenase family
DOU34_RS17870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOU34_RS17880	COG0640	Transcriptional regulator
DOU34_RS17885	COG2814	Major facilitator Superfamily
DOU34_RS17890	COG1714	RDD family
DOU34_RS17900	COG0450	alkyl hydroperoxide reductase
DOU34_RS17905	COG3634	alkyl hydroperoxide reductase activity
DOU34_RS17910	COG3177	Filamentation induced by cAMP protein fic
DOU34_RS17915	COG1113	amino acid transport
DOU34_RS17925	COG2080	2 iron, 2 sulfur cluster binding
DOU34_RS17940	COG2068	MobA-Related Protein
DOU34_RS17945	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DOU34_RS17990	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DOU34_RS17995	COG0667	Aldo Keto reductase
DOU34_RS18000	COG0456	acetyltransferase
DOU34_RS18005	COG0457	Tetratricopeptide repeat
DOU34_RS18010	COG0010	Belongs to the arginase family
DOU34_RS18015	COG0833	amino acid
DOU34_RS18020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOU34_RS18025	COG5658	integral membrane protein
DOU34_RS18030	COG0640	Transcriptional regulator
DOU34_RS18035	COG3829	transcription factor binding
DOU34_RS18045	COG0488	(ABC) transporter
DOU34_RS18060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DOU34_RS18065	COG5002	protein histidine kinase activity
DOU34_RS18070	COG0745	RESPONSE REGULATOR receiver
DOU34_RS18075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOU34_RS18080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DOU34_RS18085	COG4853	Protein conserved in bacteria
DOU34_RS18090	COG4863	YycH protein
DOU34_RS18095	COG5002	protein histidine kinase activity
DOU34_RS18100	COG0745	RESPONSE REGULATOR receiver
DOU34_RS18135	COG0346	lactoylglutathione lyase activity
DOU34_RS18140	COG0305	Participates in initiation and elongation during chromosome replication
DOU34_RS18160	COG3093	addiction module antidote protein HigA
DOU34_RS18165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOU34_RS18180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOU34_RS18185	COG0438	transferase activity, transferring glycosyl groups
DOU34_RS18205	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DOU34_RS18210	COG4241	membrane
DOU34_RS18220	COG5577	PFAM Coat F domain
DOU34_RS18225	COG1733	regulation of RNA biosynthetic process
DOU34_RS18235	COG0697	spore germination
DOU34_RS18240	COG1621	beta-fructofuranosidase activity
DOU34_RS18245	COG1621	beta-fructofuranosidase activity
DOU34_RS18250	COG1802	Transcriptional regulator
DOU34_RS18255	COG2318	DinB family
DOU34_RS18260	COG2211	Major facilitator Superfamily
DOU34_RS18265	COG0583	DNA-binding transcription factor activity
DOU34_RS18280	COG0778	Nitroreductase
DOU34_RS18285	COG1846	Transcriptional regulator
DOU34_RS18290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOU34_RS18295	COG1846	Transcriptional regulator
DOU34_RS18300	COG2153	protein acetylation
DOU34_RS18310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DOU34_RS18315	COG0583	DNA-binding transcription factor activity
DOU34_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS18325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOU34_RS18330	COG0697	spore germination
DOU34_RS18335	COG1331	Highly conserved protein containing a thioredoxin domain
DOU34_RS18345	COG1078	dGTPase activity
DOU34_RS18360	COG1331	Highly conserved protein containing a thioredoxin domain
DOU34_RS18365	COG1266	CAAX protease self-immunity
DOU34_RS18370	COG2814	Major facilitator Superfamily
DOU34_RS18370	COG0477	Major facilitator Superfamily
DOU34_RS18375	COG0346	lactoylglutathione lyase activity
DOU34_RS18380	COG1609	Transcriptional regulator
DOU34_RS18385	COG0708	Exodeoxyribonuclease III
DOU34_RS18390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOU34_RS18395	COG2169	Transcriptional regulator
DOU34_RS18405	COG0629	single-stranded DNA binding
DOU34_RS18415	COG0012	GTP binding
DOU34_RS18420	COG0243	molybdopterin cofactor binding
DOU34_RS18425	COG4481	Protein conserved in bacteria
DOU34_RS18430	COG3949	Membrane
DOU34_RS18445	COG1475	DNA binding
DOU34_RS18450	COG1192	Involved in chromosome partitioning
DOU34_RS18475	COG1847	R3H domain protein
DOU34_RS18480	COG0706	membrane insertase activity
DOU34_RS18500	COG0592	DNA-directed DNA polymerase activity
DOU34_RS18505	COG2501	S4 domain
DOU34_RS18520	COG0187	DNA topoisomerase II activity
DOU34_RS18525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOU34_RS18560	COG0517	IMP dehydrogenase activity
DOU34_RS18560	COG0516	GMP reductase activity
DOU34_RS18565	COG1686	Belongs to the peptidase S11 family
DOU34_RS18585	COG1929	Belongs to the glycerate kinase type-1 family
DOU34_RS18595	COG1428	Deoxynucleoside kinase
DOU34_RS18600	COG1428	Deoxynucleoside kinase
DOU34_RS18605	COG3858	chitin binding
DOU34_RS18605	COG1388	LysM domain
DOU34_RS18610	COG1335	isochorismatase
DOU34_RS18615	COG0590	tRNA wobble adenosine to inosine editing
DOU34_RS18625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOU34_RS18630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOU34_RS18680	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DOU34_RS18685	COG3853	Toxic anion resistance protein (TelA)
DOU34_RS18690	COG1982	Orn Lys Arg decarboxylase major
DOU34_RS18700	COG3870	Protein conserved in bacteria
DOU34_RS18705	COG1728	Protein conserved in bacteria
DOU34_RS18710	COG0470	DNA polymerase III
DOU34_RS18715	COG1774	PSP1 C-terminal conserved region
DOU34_RS18725	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DOU34_RS18735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOU34_RS18740	COG2002	toxin-antitoxin pair type II binding
DOU34_RS18745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOU34_RS18745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOU34_RS18750	COG0084	hydrolase, TatD family'
DOU34_RS18755	COG3584	3D domain protein
DOU34_RS18755	COG3583	domain protein
DOU34_RS18760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOU34_RS18765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DOU34_RS18775	COG4466	Protein conserved in bacteria
DOU34_RS18790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOU34_RS18795	COG0251	oxidation-reduction process
DOU34_RS18810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOU34_RS18830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOU34_RS18835	COG2002	toxin-antitoxin pair type II binding
DOU34_RS18840	COG2244	polysaccharide biosynthetic process
DOU34_RS18845	COG3956	TIGRFAM MazG family protein
DOU34_RS18850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DOU34_RS18865	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DOU34_RS18870	COG1098	S1 RNA binding domain
DOU34_RS18885	COG2208	phosphoserine phosphatase activity
DOU34_RS18890	COG2304	oxidoreductase activity
DOU34_RS18895	COG0515	serine threonine protein kinase
DOU34_RS18900	COG0037	tRNA processing
DOU34_RS18905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DOU34_RS18910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOU34_RS18925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOU34_RS18930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DOU34_RS18935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOU34_RS18940	COG0512	Glutamine amidotransferase of anthranilate synthase
DOU34_RS18945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS18950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOU34_RS18955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOU34_RS18960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOU34_RS18965	COG1396	sequence-specific DNA binding
DOU34_RS18970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOU34_RS18975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DOU34_RS19060	COG4463	regulation of RNA biosynthetic process
DOU34_RS19065	COG3880	PFAM UvrB UvrC protein
DOU34_RS19075	COG0542	response to heat
DOU34_RS19080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOU34_RS19085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DOU34_RS19090	COG4956	integral membrane protein (PIN domain superfamily)
DOU34_RS19110	COG1045	serine acetyltransferase
DOU34_RS19120	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOU34_RS19125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOU34_RS19130	COG3688	RNA-binding protein containing a PIN domain
DOU34_RS19135	COG1595	DNA-templated transcription, initiation
DOU34_RS19145	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DOU34_RS19150	COG0250	Participates in transcription elongation, termination and antitermination
DOU34_RS19175	COG2813	Specifically methylates the guanine in position
DOU34_RS19190	COG1358	cellular component organization or biogenesis
DOU34_RS19215	COG0596	Alpha beta hydrolase
DOU34_RS19310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOU34_RS19325	COG0201	protein transport
DOU34_RS19335	COG0024	Methionine aminopeptidase
DOU34_RS19350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DOU34_RS19375	COG1122	ATPase activity
DOU34_RS19380	COG1122	ATPase activity
DOU34_RS19385	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOU34_RS19405	COG2226	methyltransferase
DOU34_RS19410	COG2318	DinB family
DOU34_RS19420	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS19425	COG0489	protein tyrosine kinase activity
DOU34_RS19440	COG0726	polysaccharide deacetylase
DOU34_RS19500	COG0738	Major facilitator superfamily
DOU34_RS19505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS19520	COG0659	secondary active sulfate transmembrane transporter activity
DOU34_RS19525	COG0385	Bile acid
DOU34_RS19530	COG2819	hydrolase of the alpha beta superfamily
DOU34_RS19535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS19540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOU34_RS19545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DOU34_RS19550	COG2207	Transcriptional regulator
DOU34_RS19550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DOU34_RS19555	COG3876	Protein conserved in bacteria
DOU34_RS19560	COG1472	Belongs to the glycosyl hydrolase 3 family
DOU34_RS19565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DOU34_RS19570	COG1263	PTS System
DOU34_RS19570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOU34_RS19580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOU34_RS19585	COG1683	Conserved Protein
DOU34_RS19615	COG1595	DNA-templated transcription, initiation
DOU34_RS19620	COG5662	AntiSigma factor
DOU34_RS19625	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOU34_RS19630	COG4856	YbbR-like protein
DOU34_RS19670	COG1346	cytolysis
DOU34_RS19675	COG1380	Effector of murein hydrolase LrgA
DOU34_RS19680	COG1846	Transcriptional regulator
DOU34_RS19685	COG1113	amino acid transport
DOU34_RS19690	COG1011	Hydrolase
DOU34_RS19695	COG4585	Histidine kinase
DOU34_RS19700	COG2197	response regulator
DOU34_RS19705	COG1131	(ABC) transporter
DOU34_RS19725	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DOU34_RS19745	COG3321	synthase
DOU34_RS19745	COG4221	oxidoreductase activity
DOU34_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS19745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS19750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOU34_RS19750	COG0300	oxidoreductase activity
DOU34_RS19750	COG0318	PFAM AMP-dependent synthetase and ligase
DOU34_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
DOU34_RS19750	COG3321	synthase
DOU34_RS19790	COG0531	amino acid
DOU34_RS19795	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DOU34_RS19810	COG0584	glycerophosphoryl diester phosphodiesterase
DOU34_RS19815	COG2271	Major facilitator Superfamily
DOU34_RS19830	COG2368	4-hydroxyphenylacetate
DOU34_RS19840	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS19855	COG0371	Dehydrogenase
DOU34_RS19865	COG1183	phosphatidylcholine synthase activity
DOU34_RS19870	COG0586	Pfam SNARE associated Golgi protein
DOU34_RS19875	COG0688	phosphatidylethanolamine metabolic process
DOU34_RS19890	COG1301	dicarboxylic acid transport
DOU34_RS19895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOU34_RS19900	COG0833	amino acid
DOU34_RS19905	COG2040	homocysteine
DOU34_RS19910	COG1115	amino acid carrier protein
DOU34_RS19915	COG2066	Belongs to the glutaminase family
DOU34_RS19920	COG4191	Histidine kinase
DOU34_RS19925	COG0784	Response regulator, receiver
DOU34_RS19945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOU34_RS19950	COG0778	Nitroreductase
DOU34_RS19955	COG0346	lactoylglutathione lyase activity
DOU34_RS19960	COG2259	Doxx family
DOU34_RS19965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOU34_RS19980	COG3773	Cell wall hydrolase
DOU34_RS19990	COG3540	Alkaline phosphatase
DOU34_RS19995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOU34_RS20000	COG0805	protein transport
DOU34_RS20010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOU34_RS20015	COG0477	Major facilitator Superfamily
DOU34_RS20020	COG1309	transcriptional regulator
DOU34_RS20025	COG0252	asparaginase activity
DOU34_RS20030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DOU34_RS20035	COG3012	SEC-C Motif Domain Protein
DOU34_RS20035	COG1405	negative regulation of cell septum assembly
DOU34_RS20040	COG0667	Aldo Keto reductase
DOU34_RS20050	COG1595	DNA-templated transcription, initiation
DOU34_RS20080	COG0803	Belongs to the bacterial solute-binding protein 9 family
DOU34_RS20085	COG1121	(ABC) transporter
DOU34_RS20090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DOU34_RS20095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOU34_RS20100	COG2310	stress, protein
DOU34_RS20105	COG2310	stress, protein
DOU34_RS20110	COG2310	stress, protein
DOU34_RS20115	COG0861	Integral membrane protein TerC family
DOU34_RS20125	COG3853	Toxic anion resistance protein (TelA)
DOU34_RS20130	COG0477	Major facilitator Superfamily
DOU34_RS20215	COG4824	toxin secretion phage lysis holin
DOU34_RS20230	COG4195	phage-related replication protein
DOU34_RS20265	COG1396	sequence-specific DNA binding
DOU34_RS20310	COG3331	DNA recombination
DOU34_RS20315	COG0629	single-stranded DNA binding
DOU34_RS20385	COG1595	DNA-templated transcription, initiation
DOU34_RS20390	COG3728	DNA packaging
DOU34_RS20495	COG4824	toxin secretion phage lysis holin
DOU34_RS20500	COG5632	N-Acetylmuramoyl-L-alanine amidase
DOU34_RS20500	COG3409	Peptidoglycan-binding domain 1 protein
DOU34_RS20510	COG4195	phage-related replication protein
DOU34_RS20545	COG1396	sequence-specific DNA binding
DOU34_RS20595	COG0629	single-stranded DNA binding
DOU34_RS20665	COG1595	DNA-templated transcription, initiation