locus-tag	class	description
S101267_RS00010	COG0592	DNA-directed DNA polymerase activity
S101267_RS00015	COG2501	S4 domain
S101267_RS00030	COG0187	DNA topoisomerase II activity
S101267_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101267_RS00070	COG0517	IMP dehydrogenase activity
S101267_RS00070	COG0516	GMP reductase activity
S101267_RS00075	COG1686	Belongs to the peptidase S11 family
S101267_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
S101267_RS00105	COG1428	Deoxynucleoside kinase
S101267_RS00110	COG1428	Deoxynucleoside kinase
S101267_RS00115	COG1388	LysM domain
S101267_RS00115	COG3858	chitin binding
S101267_RS00120	COG1335	isochorismatase
S101267_RS00125	COG0590	tRNA wobble adenosine to inosine editing
S101267_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S101267_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S101267_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S101267_RS00195	COG3853	Toxic anion resistance protein (TelA)
S101267_RS00200	COG1982	Orn Lys Arg decarboxylase major
S101267_RS00210	COG3870	Protein conserved in bacteria
S101267_RS00215	COG1728	Protein conserved in bacteria
S101267_RS00220	COG0470	DNA polymerase III
S101267_RS00225	COG1774	PSP1 C-terminal conserved region
S101267_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S101267_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S101267_RS00250	COG2002	toxin-antitoxin pair type II binding
S101267_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_RS00260	COG0084	hydrolase, TatD family'
S101267_RS00265	COG3584	3D domain protein
S101267_RS00265	COG3583	domain protein
S101267_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101267_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S101267_RS00285	COG4466	Protein conserved in bacteria
S101267_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101267_RS00305	COG0251	oxidation-reduction process
S101267_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S101267_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S101267_RS00345	COG2002	toxin-antitoxin pair type II binding
S101267_RS00350	COG2244	polysaccharide biosynthetic process
S101267_RS00355	COG3956	TIGRFAM MazG family protein
S101267_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S101267_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S101267_RS00380	COG1098	S1 RNA binding domain
S101267_RS00395	COG2208	phosphoserine phosphatase activity
S101267_RS00400	COG2304	oxidoreductase activity
S101267_RS00405	COG0515	serine threonine protein kinase
S101267_RS00410	COG0037	tRNA processing
S101267_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
S101267_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101267_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101267_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101267_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
S101267_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S101267_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S101267_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S101267_RS00475	COG1396	sequence-specific DNA binding
S101267_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101267_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S101267_RS00565	COG4463	regulation of RNA biosynthetic process
S101267_RS00570	COG3880	PFAM UvrB UvrC protein
S101267_RS00580	COG0542	response to heat
S101267_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S101267_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S101267_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
S101267_RS00615	COG1045	serine acetyltransferase
S101267_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S101267_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101267_RS00635	COG3688	RNA-binding protein containing a PIN domain
S101267_RS00640	COG1595	DNA-templated transcription, initiation
S101267_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101267_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
S101267_RS00680	COG2813	Specifically methylates the guanine in position
S101267_RS00695	COG1358	cellular component organization or biogenesis
S101267_RS00720	COG0596	Alpha beta hydrolase
S101267_RS00830	COG0201	protein transport
S101267_RS00840	COG0024	Methionine aminopeptidase
S101267_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S101267_RS00880	COG1122	ATPase activity
S101267_RS00885	COG1122	ATPase activity
S101267_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101267_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
S101267_RS00910	COG2226	methyltransferase
S101267_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS00925	COG0489	protein tyrosine kinase activity
S101267_RS00935	COG2194	sulfuric ester hydrolase activity
S101267_RS00940	COG0726	polysaccharide deacetylase
S101267_RS01000	COG0738	Major facilitator superfamily
S101267_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101267_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
S101267_RS01025	COG0385	Bile acid
S101267_RS01030	COG2819	hydrolase of the alpha beta superfamily
S101267_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_RS01050	COG2207	Transcriptional regulator
S101267_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_RS01055	COG3876	Protein conserved in bacteria
S101267_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
S101267_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_RS01070	COG1263	PTS System
S101267_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_RS01085	COG1683	Conserved Protein
S101267_RS01115	COG1595	DNA-templated transcription, initiation
S101267_RS01120	COG5662	AntiSigma factor
S101267_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101267_RS01130	COG4856	YbbR-like protein
S101267_RS01180	COG1346	cytolysis
S101267_RS01185	COG1380	Effector of murein hydrolase LrgA
S101267_RS01190	COG1846	Transcriptional regulator
S101267_RS01195	COG1113	amino acid transport
S101267_RS01200	COG1011	Hydrolase
S101267_RS01205	COG4585	Histidine kinase
S101267_RS01210	COG2197	response regulator
S101267_RS01215	COG1131	(ABC) transporter
S101267_RS01225	COG1511	domain protein
S101267_RS01225	COG0842	Transport permease protein
S101267_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_RS01275	COG2271	Major facilitator Superfamily
S101267_RS01290	COG2368	4-hydroxyphenylacetate
S101267_RS01305	COG0371	Dehydrogenase
S101267_RS01315	COG1183	phosphatidylcholine synthase activity
S101267_RS01320	COG0586	Pfam SNARE associated Golgi protein
S101267_RS01325	COG0688	phosphatidylethanolamine metabolic process
S101267_RS01340	COG1301	dicarboxylic acid transport
S101267_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_RS01350	COG0833	amino acid
S101267_RS01355	COG2040	homocysteine
S101267_RS01360	COG1115	amino acid carrier protein
S101267_RS01370	COG4191	Histidine kinase
S101267_RS01375	COG0784	Response regulator, receiver
S101267_RS01380	COG3173	Aminoglycoside phosphotransferase
S101267_RS01395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_RS01400	COG0778	Nitroreductase
S101267_RS01405	COG0346	lactoylglutathione lyase activity
S101267_RS01410	COG2259	Doxx family
S101267_RS01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS01435	COG3773	Cell wall hydrolase
S101267_RS01440	COG3540	Alkaline phosphatase
S101267_RS01445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101267_RS01450	COG0805	protein transport
S101267_RS01455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
S101267_RS01460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101267_RS01465	COG0477	Major facilitator Superfamily
S101267_RS01470	COG1309	transcriptional regulator
S101267_RS01480	COG3012	SEC-C Motif Domain Protein
S101267_RS01480	COG1405	negative regulation of cell septum assembly
S101267_RS01485	COG0667	Aldo Keto reductase
S101267_RS01495	COG1595	DNA-templated transcription, initiation
S101267_RS01500	COG1595	DNA-templated transcription, initiation
S101267_RS01505	COG1876	peptidase activity
S101267_RS01510	COG0457	Tetratricopeptide repeat
S101267_RS01515	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS01520	COG0366	Alpha amylase catalytic
S101267_RS01530	COG1695	Transcriptional regulator
S101267_RS01535	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101267_RS01540	COG1121	(ABC) transporter
S101267_RS01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101267_RS01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS01555	COG2310	stress, protein
S101267_RS01560	COG2310	stress, protein
S101267_RS01565	COG2310	stress, protein
S101267_RS01570	COG0861	Integral membrane protein TerC family
S101267_RS01580	COG3853	Toxic anion resistance protein (TelA)
S101267_RS01585	COG0477	Major facilitator Superfamily
S101267_RS01590	COG4175	Glycine betaine
S101267_RS01590	COG0517	IMP dehydrogenase activity
S101267_RS01595	COG4176	ABC-type proline glycine betaine transport system permease component
S101267_RS01600	COG2113	Glycine betaine
S101267_RS01605	COG1473	amidohydrolase
S101267_RS01620	COG1714	RDD family
S101267_RS01630	COG2814	Major facilitator Superfamily
S101267_RS01635	COG1846	Transcriptional regulator
S101267_RS01650	COG3403	YqcI/YcgG family
S101267_RS01655	COG1113	amino acid transport
S101267_RS01660	COG3665	Urea carboxylase-associated protein
S101267_RS01670	COG1082	Xylose isomerase domain protein TIM barrel
S101267_RS01675	COG2271	Major facilitator Superfamily
S101267_RS01680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
S101267_RS01685	COG3458	cephalosporin-C deacetylase activity
S101267_RS01690	COG3541	Predicted nucleotidyltransferase
S101267_RS01695	COG0506	proline dehydrogenase activity
S101267_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS01705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_RS01710	COG2508	Transcriptional regulator
S101267_RS01720	COG1587	Uroporphyrinogen-III synthase
S101267_RS01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101267_RS01725	COG2146	nitrite reductase [NAD(P)H] activity
S101267_RS01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101267_RS01735	COG2223	nitrite transmembrane transporter activity
S101267_RS01740	COG0523	cobalamin synthesis protein
S101267_RS01745	COG1063	alcohol dehydrogenase
S101267_RS01750	COG1714	RDD family
S101267_RS01760	COG2723	6-phospho-beta-galactosidase activity
S101267_RS01770	COG3209	COG3209 Rhs family protein
S101267_RS01775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S101267_RS01780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S101267_RS01785	COG1733	regulation of RNA biosynthetic process
S101267_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS01810	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S101267_RS01825	COG2364	Membrane
S101267_RS01830	COG1126	abc transporter atp-binding protein
S101267_RS01835	COG0765	amino acid transport
S101267_RS01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS01845	COG0583	DNA-binding transcription factor activity
S101267_RS01850	COG0163	prenyltransferase activity
S101267_RS01855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S101267_RS01870	COG3104	oligopeptide transport
S101267_RS01875	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS01885	COG0697	spore germination
S101267_RS01895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101267_RS01900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS01905	COG0456	acetyltransferase
S101267_RS01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS01915	COG0765	amino acid transport
S101267_RS01920	COG1126	abc transporter atp-binding protein
S101267_RS01925	COG1473	amidohydrolase
S101267_RS01930	COG2079	MmgE PrpD family protein
S101267_RS01935	COG1136	(ABC) transporter
S101267_RS01940	COG0577	efflux transmembrane transporter activity
S101267_RS01945	COG0745	RESPONSE REGULATOR receiver
S101267_RS01950	COG5002	protein histidine kinase activity
S101267_RS01950	COG3850	Histidine kinase
S101267_RS01955	COG0457	Tetratricopeptide repeat
S101267_RS01970	COG0527	aspartate kinase activity
S101267_RS01975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS01980	COG4605	iron ion homeostasis
S101267_RS01985	COG4604	ABC transporter, ATP-binding protein
S101267_RS01990	COG4607	ABC-type enterochelin transport system periplasmic component
S101267_RS01995	COG2814	Major facilitator Superfamily
S101267_RS02000	COG1309	transcriptional regulator
S101267_RS02005	COG0778	Nitroreductase
S101267_RS02010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101267_RS02015	COG0640	Transcriptional regulator
S101267_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS02025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101267_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS02035	COG4975	Glucose uptake
S101267_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS02045	COG4549	nuclear export factor GLE1
S101267_RS02050	COG2372	response to copper ion
S101267_RS02050	COG1276	copper resistance
S101267_RS02055	COG1349	DNA-binding transcription factor activity
S101267_RS02065	COG2213	PTS system mannitol-specific
S101267_RS02070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101267_RS02090	COG0561	phosphatase activity
S101267_RS02100	COG1914	H( )-stimulated, divalent metal cation uptake system
S101267_RS02110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S101267_RS02115	COG1984	allophanate hydrolase subunit 2
S101267_RS02120	COG1414	Transcriptional regulator
S101267_RS02125	COG2755	lipolytic protein G-D-S-L family
S101267_RS02135	COG2329	Antibiotic biosynthesis monooxygenase
S101267_RS02140	COG0768	penicillin binding
S101267_RS02145	COG4989	oxidoreductase activity
S101267_RS02150	COG3711	transcriptional antiterminator
S101267_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS02165	COG1917	Cupin 2, conserved barrel domain protein
S101267_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_RS02175	COG3871	stress protein (general stress protein 26)
S101267_RS02185	COG2814	Major facilitator Superfamily
S101267_RS02190	COG1522	sequence-specific DNA binding
S101267_RS02195	COG0551	DNA topoisomerase type I activity
S101267_RS02195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101267_RS02200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S101267_RS02205	COG3706	GGDEF domain
S101267_RS02210	COG5298	Protein conserved in bacteria
S101267_RS02215	COG1215	transferase activity, transferring glycosyl groups
S101267_RS02225	COG0531	amino acid
S101267_RS02230	COG0028	Belongs to the TPP enzyme family
S101267_RS02265	COG0457	Tetratricopeptide repeat
S101267_RS02280	COG1914	H( )-stimulated, divalent metal cation uptake system
S101267_RS02290	COG4876	unkown
S101267_RS02300	COG2076	Multidrug Resistance protein
S101267_RS02305	COG2217	Heavy metal translocating P-type atpase
S101267_RS02310	COG3729	General stress protein
S101267_RS02315	COG0662	Cupin 2, conserved barrel domain protein
S101267_RS02320	COG2329	Antibiotic biosynthesis monooxygenase
S101267_RS02325	COG3546	catalase activity
S101267_RS02335	COG3290	protein histidine kinase activity
S101267_RS02340	COG4565	transcriptional regulatory protein
S101267_RS02345	COG1301	dicarboxylic acid transport
S101267_RS02350	COG0628	permease
S101267_RS02355	COG1131	(ABC) transporter
S101267_RS02360	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_RS02370	COG1960	acyl-CoA dehydrogenase activity
S101267_RS02390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_RS02395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS02405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S101267_RS02410	COG0513	Belongs to the DEAD box helicase family
S101267_RS02415	COG3402	PFAM membrane-flanked domain
S101267_RS02420	COG3428	Bacterial PH domain
S101267_RS02425	COG0705	Rhomboid family
S101267_RS02435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S101267_RS02440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101267_RS02445	COG0864	Transcriptional regulator
S101267_RS02450	COG2337	Toxic component of a toxin-antitoxin (TA) module
S101267_RS02455	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS02465	COG2172	sigma factor antagonist activity
S101267_RS02470	COG2208	phosphoserine phosphatase activity
S101267_RS02475	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS02485	COG1191	sigma factor activity
S101267_RS02490	COG2208	phosphoserine phosphatase activity
S101267_RS02495	COG2183	response to ionizing radiation
S101267_RS02550	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS02570	COG1191	sigma factor activity
S101267_RS02590	COG0582	viral genome integration into host DNA
S101267_RS02595	COG2856	Zn peptidase
S101267_RS02600	COG1396	sequence-specific DNA binding
S101267_RS02630	COG1674	ftsk spoiiie
S101267_RS02635	COG2946	Replication initiation factor
S101267_RS02685	COG0433	COG0433 Predicted ATPase
S101267_RS02695	COG5644	endopeptidase inhibitor activity
S101267_RS02700	COG0791	NLP P60 protein
S101267_RS02700	COG0741	lytic transglycosylase activity
S101267_RS02735	COG0457	Tetratricopeptide repeat
S101267_RS02745	COG5444	nuclease activity
S101267_RS02755	COG1959	2 iron, 2 sulfur cluster binding
S101267_RS02765	COG1278	Cold shock
S101267_RS02775	COG1794	racemase activity, acting on amino acids and derivatives
S101267_RS02795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS02800	COG0477	Major facilitator Superfamily
S101267_RS02815	COG0277	FAD linked oxidase domain protein
S101267_RS02835	COG0662	Cupin 2, conserved barrel domain protein
S101267_RS02840	COG0456	acetyltransferase
S101267_RS02845	COG2207	Transcriptional regulator
S101267_RS02845	COG3708	Transcriptional regulator
S101267_RS02870	COG1064	alcohol dehydrogenase
S101267_RS02875	COG0789	Transcriptional regulator
S101267_RS02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS02890	COG2808	Putative FMN-binding domain
S101267_RS02895	COG2814	Major facilitator Superfamily
S101267_RS02900	COG1309	transcriptional regulator
S101267_RS02905	COG0697	spore germination
S101267_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS02915	COG5577	PFAM Coat F domain
S101267_RS02925	COG1063	alcohol dehydrogenase
S101267_RS02930	COG5577	PFAM Coat F domain
S101267_RS02940	COG2409	Drug exporters of the RND superfamily
S101267_RS02945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
S101267_RS02950	COG0488	(ABC) transporter
S101267_RS02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_RS02960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS02970	COG2814	Major facilitator Superfamily
S101267_RS02975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_RS02985	COG0730	response to heat
S101267_RS02990	COG0456	acetyltransferase
S101267_RS02995	COG0789	Transcriptional regulator
S101267_RS02995	COG4978	Transcriptional regulator
S101267_RS03000	COG0697	spore germination
S101267_RS03005	COG1051	belongs to the nudix hydrolase family
S101267_RS03010	COG0596	Alpha beta hydrolase
S101267_RS03015	COG0473	3-isopropylmalate dehydrogenase activity
S101267_RS03020	COG1802	Transcriptional regulator
S101267_RS03035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_RS03040	COG1388	LysM domain
S101267_RS03045	COG2814	Major facilitator Superfamily
S101267_RS03050	COG2188	Transcriptional regulator
S101267_RS03055	COG2186	Transcriptional regulator
S101267_RS03060	COG2807	transmembrane transport
S101267_RS03065	COG2076	Multidrug Resistance protein
S101267_RS03070	COG2076	Multidrug Resistance protein
S101267_RS03075	COG1309	transcriptional regulator
S101267_RS03080	COG0531	amino acid
S101267_RS03090	COG3832	glyoxalase III activity
S101267_RS03095	COG0604	alcohol dehydrogenase
S101267_RS03100	COG2814	Major facilitator Superfamily
S101267_RS03140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S101267_RS03145	COG0802	atpase or kinase
S101267_RS03150	COG1214	PFAM Peptidase M22, glycoprotease
S101267_RS03155	COG0456	acetyltransferase
S101267_RS03160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S101267_RS03165	COG0488	(ABC) transporter
S101267_RS03180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101267_RS03185	COG0805	protein transport
S101267_RS03195	COG1266	CAAX protease self-immunity
S101267_RS03215	COG2856	Zn peptidase
S101267_RS03230	COG1396	sequence-specific DNA binding
S101267_RS03270	COG5377	YqaJ viral recombinase family
S101267_RS03275	COG3723	Recombinational DNA repair protein, rece pathway
S101267_RS03280	COG3935	DnaD domain protein
S101267_RS03285	COG1484	DNA-dependent DNA replication
S101267_RS03390	COG1595	DNA-templated transcription, initiation
S101267_RS03415	COG5484	DNA packaging
S101267_RS03420	COG1783	phage Terminase large subunit
S101267_RS03545	COG1388	LysM domain
S101267_RS03545	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS03545	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS03560	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS03575	COG0457	Tetratricopeptide repeat
S101267_RS03580	COG1063	alcohol dehydrogenase
S101267_RS03585	COG2211	Major facilitator Superfamily
S101267_RS03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_RS03600	COG1842	Phage shock protein A
S101267_RS03605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101267_RS03610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S101267_RS03615	COG4260	virion core protein, lumpy skin disease virus
S101267_RS03620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101267_RS03620	COG2755	lipolytic protein G-D-S-L family
S101267_RS03630	COG1595	DNA-templated transcription, initiation
S101267_RS03635	COG1063	alcohol dehydrogenase
S101267_RS03640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S101267_RS03645	COG0823	Involved in the tonB-independent uptake of proteins
S101267_RS03655	COG2132	Multicopper oxidase
S101267_RS03660	COG1113	amino acid transport
S101267_RS03675	COG0714	Associated with various cellular activities
S101267_RS03680	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
S101267_RS03685	COG1305	Transglutaminase-like
S101267_RS03705	COG2252	PERMEase
S101267_RS03710	COG3064	Membrane
S101267_RS03730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S101267_RS03735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S101267_RS03740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S101267_RS03745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S101267_RS03750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101267_RS03765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S101267_RS03775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S101267_RS03780	COG0138	bifunctional purine biosynthesis protein purh
S101267_RS03785	COG0151	Belongs to the GarS family
S101267_RS03790	COG1522	sequence-specific DNA binding
S101267_RS03795	COG0531	amino acid
S101267_RS03805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101267_RS03810	COG1470	cell adhesion involved in biofilm formation
S101267_RS03815	COG4496	protein, YerC YecD
S101267_RS03820	COG0069	glutamate synthase activity
S101267_RS03835	COG0210	DNA helicase
S101267_RS03845	COG4851	CamS sex pheromone cAM373 precursor
S101267_RS03850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_RS03855	COG1285	pathogenesis
S101267_RS03860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_RS03880	COG1309	transcriptional regulator
S101267_RS03885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S101267_RS03890	COG1597	lipid kinase activity
S101267_RS03895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101267_RS03905	COG1131	(ABC) transporter
S101267_RS03935	COG5444	nuclease activity
S101267_RS03940	COG5444	nuclease activity
S101267_RS03970	COG3546	catalase activity
S101267_RS03975	COG0454	-acetyltransferase
S101267_RS03985	COG2323	membrane
S101267_RS03990	COG2329	Antibiotic biosynthesis monooxygenase
S101267_RS03995	COG0346	lactoylglutathione lyase activity
S101267_RS04000	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS04005	COG5583	Uncharacterized small protein (DUF2292)
S101267_RS04010	COG0196	riboflavin kinase activity
S101267_RS04015	COG0670	Belongs to the BI1 family
S101267_RS04020	COG1846	Transcriptional regulator
S101267_RS04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101267_RS04035	COG2124	cytochrome p450
S101267_RS04035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_RS04045	COG1368	sulfuric ester hydrolase activity
S101267_RS04050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S101267_RS04055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_RS04060	COG1442	glycosyl transferase family 8
S101267_RS04065	COG1216	Glycosyl transferase, family 2
S101267_RS04070	COG1442	glycosyl transferase family 8
S101267_RS04075	COG2223	nitrite transmembrane transporter activity
S101267_RS04080	COG0531	amino acid
S101267_RS04085	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS04090	COG0840	transmembrane signaling receptor activity
S101267_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS04100	COG0457	Tetratricopeptide repeat
S101267_RS04100	COG0463	Glycosyl transferase, family 2
S101267_RS04105	COG0488	(ABC) transporter
S101267_RS04110	COG0789	Transcriptional regulator
S101267_RS04115	COG2814	Major facilitator Superfamily
S101267_RS04120	COG0488	(ABC) transporter
S101267_RS04125	COG0513	Belongs to the DEAD box helicase family
S101267_RS04145	COG3866	Pectate lyase
S101267_RS04150	COG0471	metal ion transport
S101267_RS04170	COG2972	Histidine kinase
S101267_RS04170	COG0745	RESPONSE REGULATOR receiver
S101267_RS04185	COG3764	Sortase (surface protein transpeptidase)
S101267_RS04190	COG3290	protein histidine kinase activity
S101267_RS04195	COG4565	transcriptional regulatory protein
S101267_RS04200	COG3181	Tripartite tricarboxylate transporter family receptor
S101267_RS04205	COG2851	Citrate transporter
S101267_RS04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS04215	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S101267_RS04225	COG2258	MOSC domain
S101267_RS04245	COG0024	Methionine aminopeptidase
S101267_RS04250	COG1263	PTS System
S101267_RS04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS04260	COG1368	sulfuric ester hydrolase activity
S101267_RS04270	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_RS04285	COG1263	PTS System
S101267_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS04290	COG0366	Alpha amylase catalytic
S101267_RS04295	COG2188	Transcriptional regulator
S101267_RS04300	COG0778	Nitroreductase
S101267_RS04315	COG0737	Belongs to the 5'-nucleotidase family
S101267_RS04320	COG0693	protein deglycase activity
S101267_RS04325	COG1609	Transcriptional regulator
S101267_RS04340	COG2814	Major facilitator Superfamily
S101267_RS04350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101267_RS04355	COG4980	gas vesicle protein
S101267_RS04360	COG1295	ribonuclease BN
S101267_RS04365	COG0477	Major facilitator Superfamily
S101267_RS04370	COG0387	Pfam Sodium calcium exchanger
S101267_RS04380	COG0668	transmembrane transport
S101267_RS04385	COG0535	radical SAM domain protein
S101267_RS04395	COG0726	polysaccharide deacetylase
S101267_RS04410	COG0598	Magnesium transport protein CorA
S101267_RS04415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101267_RS04420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101267_RS04435	COG1132	(ABC) transporter
S101267_RS04440	COG0515	serine threonine protein kinase
S101267_RS04450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101267_RS04455	COG4637	Psort location Cytoplasmic, score
S101267_RS04460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_RS04465	COG0022	dehydrogenase e1 component
S101267_RS04470	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_RS04475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_RS04490	COG1486	melibiose metabolic process
S101267_RS04495	COG1737	Transcriptional regulator
S101267_RS04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS04500	COG1263	PTS System
S101267_RS04505	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS04510	COG1132	(ABC) transporter
S101267_RS04515	COG1132	(ABC) transporter
S101267_RS04520	COG2259	Doxx family
S101267_RS04525	COG2514	catechol 2,3-dioxygenase activity
S101267_RS04535	COG1695	Transcriptional regulator
S101267_RS04540	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101267_RS04545	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S101267_RS04550	COG2732	(Barnase) inhibitor
S101267_RS04555	COG2318	DinB family
S101267_RS04560	COG2814	Major facilitator Superfamily
S101267_RS04565	COG1846	Transcriptional regulator
S101267_RS04570	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S101267_RS04570	COG0392	lysyltransferase activity
S101267_RS04575	COG0384	phenazine biosynthesis protein PhzF
S101267_RS04580	COG0778	Nitroreductase
S101267_RS04595	COG1090	epimerase
S101267_RS04620	COG3591	Belongs to the peptidase S1B family
S101267_RS04635	COG3103	Sh3 type 3 domain protein
S101267_RS04640	COG5658	integral membrane protein
S101267_RS04650	COG0463	Glycosyl transferase, family 2
S101267_RS04655	COG4485	Bacterial membrane protein, YfhO
S101267_RS04660	COG1988	membrane-bound metal-dependent
S101267_RS04665	COG1194	a g-specific adenine glycosylase
S101267_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS04695	COG1132	(ABC) transporter
S101267_RS04700	COG4129	membrane
S101267_RS04710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S101267_RS04715	COG0735	belongs to the Fur family
S101267_RS04930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S101267_RS04935	COG0582	viral genome integration into host DNA
S101267_RS04940	COG4980	gas vesicle protein
S101267_RS04940	COG1674	ftsk spoiiie
S101267_RS04975	COG0740	serine-type endopeptidase activity
S101267_RS05020	COG3953	SLT domain
S101267_RS05020	COG5412	phage tail tape measure protein
S101267_RS05035	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS05055	COG4824	toxin secretion phage lysis holin
S101267_RS05060	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS05080	COG1757	Na H antiporter
S101267_RS05085	COG3340	Belongs to the peptidase S51 family
S101267_RS05095	COG0277	FAD linked oxidase domain protein
S101267_RS05105	COG0747	negative chemotaxis
S101267_RS05110	COG0601	transmembrane transport
S101267_RS05115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_RS05120	COG0444	Belongs to the ABC transporter superfamily
S101267_RS05130	COG0753	catalase activity
S101267_RS05140	COG1116	anion transmembrane transporter activity
S101267_RS05145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101267_RS05150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101267_RS05175	COG1476	TRANSCRIPTIONal
S101267_RS05185	COG3382	B3 4 domain protein
S101267_RS05190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S101267_RS05200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S101267_RS05205	COG0789	Transcriptional regulator
S101267_RS05210	COG1664	Polymer-forming cytoskeletal
S101267_RS05215	COG1664	Polymer-forming cytoskeletal
S101267_RS05220	COG2766	serine protein kinase
S101267_RS05230	COG1846	Transcriptional regulator
S101267_RS05235	COG1566	PFAM secretion protein HlyD family protein
S101267_RS05240	COG2814	Major facilitator Superfamily
S101267_RS05245	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101267_RS05260	COG1725	Transcriptional regulator
S101267_RS05265	COG1131	(ABC) transporter
S101267_RS05270	COG1131	(ABC) transporter
S101267_RS05275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_RS05280	COG1278	Cold shock
S101267_RS05290	COG1464	Belongs to the NlpA lipoprotein family
S101267_RS05295	COG3706	GGDEF domain
S101267_RS05300	COG1823	symporter activity
S101267_RS05305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_RS05325	COG5577	PFAM Coat F domain
S101267_RS05330	COG1525	nuclease
S101267_RS05330	COG0737	Belongs to the 5'-nucleotidase family
S101267_RS05330	COG4085	toxin activity
S101267_RS05335	COG3764	Sortase (surface protein transpeptidase)
S101267_RS05340	COG0564	pseudouridine synthase activity
S101267_RS05350	COG0517	IMP dehydrogenase activity
S101267_RS05355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101267_RS05360	COG3153	acetyltransferase
S101267_RS05360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101267_RS05365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_RS05370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S101267_RS05375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S101267_RS05385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S101267_RS05390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101267_RS05395	COG2203	Gaf domain
S101267_RS05395	COG4585	Histidine kinase
S101267_RS05400	COG2197	response regulator
S101267_RS05405	COG0431	NADPH-dependent FMN reductase
S101267_RS05420	COG0791	NLP P60 protein
S101267_RS05420	COG1388	LysM domain
S101267_RS05425	COG1959	2 iron, 2 sulfur cluster binding
S101267_RS05430	COG0668	transmembrane transport
S101267_RS05435	COG2719	SpoVR family
S101267_RS05440	COG1785	Belongs to the alkaline phosphatase family
S101267_RS05445	COG0791	NLP P60 protein
S101267_RS05445	COG1388	LysM domain
S101267_RS05450	COG0583	DNA-binding transcription factor activity
S101267_RS05455	COG0372	Belongs to the citrate synthase family
S101267_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS05465	COG0531	amino acid
S101267_RS05470	COG0733	neurotransmitter:sodium symporter activity
S101267_RS05485	COG1595	DNA-templated transcription, initiation
S101267_RS05490	COG0204	Acyl-transferase
S101267_RS05495	COG1253	flavin adenine dinucleotide binding
S101267_RS05500	COG0789	Transcriptional regulator
S101267_RS05505	COG0436	Aminotransferase
S101267_RS05510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_RS05515	COG1253	flavin adenine dinucleotide binding
S101267_RS05520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101267_RS05525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101267_RS05530	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_RS05540	COG0668	transmembrane transport
S101267_RS05545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
S101267_RS05550	COG0726	polysaccharide deacetylase
S101267_RS05555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_RS05560	COG3226	Transcriptional regulator
S101267_RS05570	COG0589	response to stress
S101267_RS05575	COG1132	(ABC) transporter
S101267_RS05580	COG1132	(ABC) transporter
S101267_RS05585	COG0702	epimerase
S101267_RS05610	COG0189	ligase activity
S101267_RS05615	COG0189	ligase activity
S101267_RS05630	COG0561	phosphatase activity
S101267_RS05635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101267_RS05645	COG0475	glutathione-regulated potassium exporter activity
S101267_RS05650	COG0490	domain, Protein
S101267_RS05660	COG1024	Enoyl-CoA hydratase
S101267_RS05670	COG4152	abc transporter atp-binding protein
S101267_RS05675	COG1668	transmembrane transport
S101267_RS05680	COG0420	3'-5' exonuclease activity
S101267_RS05685	COG4717	serine-type aminopeptidase activity
S101267_RS05700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101267_RS05740	COG4980	gas vesicle protein
S101267_RS05755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S101267_RS05760	COG0537	adenosine 5'-monophosphoramidase activity
S101267_RS05765	COG1131	(ABC) transporter
S101267_RS05770	COG4473	ABC transporter
S101267_RS05780	COG1473	amidohydrolase
S101267_RS05785	COG3069	C4-dicarboxylate transmembrane transporter activity
S101267_RS05790	COG2329	Antibiotic biosynthesis monooxygenase
S101267_RS05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_RS05805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
S101267_RS05810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
S101267_RS05815	COG1309	transcriptional regulator
S101267_RS05820	COG1511	domain protein
S101267_RS05825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS05835	COG1363	Peptidase, m42
S101267_RS05840	COG1301	dicarboxylic acid transport
S101267_RS05850	COG1234	tRNA 3'-trailer cleavage
S101267_RS05855	COG0095	Lipoate-protein ligase
S101267_RS05860	COG0702	epimerase
S101267_RS05865	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_RS05875	COG0501	Belongs to the peptidase M48B family
S101267_RS05880	COG1404	Belongs to the peptidase S8 family
S101267_RS05890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101267_RS05895	COG0406	alpha-ribazole phosphatase activity
S101267_RS05900	COG0183	Belongs to the thiolase family
S101267_RS05905	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_RS05910	COG1268	BioY protein
S101267_RS05915	COG0840	transmembrane signaling receptor activity
S101267_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS05935	COG4903	ComK protein
S101267_RS05940	COG5646	InterPro IPR014922
S101267_RS05965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_RS05980	COG0398	Pfam SNARE associated Golgi protein
S101267_RS05985	COG0681	Belongs to the peptidase S26 family
S101267_RS05990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101267_RS05995	COG1846	Transcriptional regulator
S101267_RS06000	COG3180	Ammonia monooxygenase
S101267_RS06005	COG2814	Major facilitator Superfamily
S101267_RS06015	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S101267_RS06020	COG2323	membrane
S101267_RS06035	COG0420	3'-5' exonuclease activity
S101267_RS06040	COG0419	ATPase involved in DNA repair
S101267_RS06045	COG1403	HNH endonuclease
S101267_RS06085	COG0179	Fumarylacetoacetate (FAA) hydrolase
S101267_RS06095	COG1404	Belongs to the peptidase S8 family
S101267_RS06105	COG0367	asparagine synthase
S101267_RS06110	COG1562	ergosterol biosynthetic process
S101267_RS06115	COG0534	Mate efflux family protein
S101267_RS06120	COG2207	Transcriptional regulator
S101267_RS06120	COG1917	Cupin 2, conserved barrel domain protein
S101267_RS06125	COG1609	Transcriptional regulator
S101267_RS06130	COG0673	inositol 2-dehydrogenase activity
S101267_RS06135	COG2318	DinB family
S101267_RS06140	COG1279	arginine transmembrane transporter activity
S101267_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS06150	COG1357	PFAM Pentapeptide repeats (8 copies)
S101267_RS06155	COG2153	protein acetylation
S101267_RS06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S101267_RS06160	COG0646	methionine synthase
S101267_RS06170	COG2996	Protein conserved in bacteria
S101267_RS06175	COG1744	ABC transporter substrate-binding protein PnrA-like
S101267_RS06180	COG0840	transmembrane signaling receptor activity
S101267_RS06185	COG2124	cytochrome p450
S101267_RS06195	COG1307	EDD domain protein, DegV family
S101267_RS06200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS06215	COG0561	phosphatase activity
S101267_RS06220	COG1073	alpha beta
S101267_RS06225	COG2151	metal-sulfur cluster biosynthetic enzyme
S101267_RS06235	COG0277	FAD linked oxidase domain protein
S101267_RS06240	COG2271	Major facilitator Superfamily
S101267_RS06250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
S101267_RS06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101267_RS06265	COG0505	Belongs to the CarA family
S101267_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101267_RS06275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
S101267_RS06295	COG2267	carboxylic ester hydrolase activity
S101267_RS06305	COG1744	ABC transporter substrate-binding protein PnrA-like
S101267_RS06320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS06325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101267_RS06330	COG5504	Zn-dependent protease
S101267_RS06335	COG0444	Belongs to the ABC transporter superfamily
S101267_RS06340	COG4608	Belongs to the ABC transporter superfamily
S101267_RS06350	COG0601	transmembrane transport
S101267_RS06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_RS06365	COG0180	Tryptophanyl-tRNA synthetase
S101267_RS06375	COG4166	transmembrane transport
S101267_RS06380	COG0601	transmembrane transport
S101267_RS06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_RS06390	COG0444	Belongs to the ABC transporter superfamily
S101267_RS06395	COG4608	Belongs to the ABC transporter superfamily
S101267_RS06405	COG0456	acetyltransferase
S101267_RS06410	COG1393	Belongs to the ArsC family
S101267_RS06415	COG0861	Integral membrane protein TerC family
S101267_RS06420	COG4862	establishment of competence for transformation
S101267_RS06425	COG4469	Competence protein
S101267_RS06430	COG1164	Oligoendopeptidase f
S101267_RS06440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101267_RS06445	COG2346	COG2346, Truncated hemoglobins
S101267_RS06450	COG0741	lytic transglycosylase activity
S101267_RS06455	COG4116	CYTH
S101267_RS06465	COG2357	RelA SpoT domain protein
S101267_RS06470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101267_RS06475	COG0564	pseudouridine synthase activity
S101267_RS06485	COG0569	domain protein
S101267_RS06485	COG0475	glutathione-regulated potassium exporter activity
S101267_RS06490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S101267_RS06495	COG0352	thiamine-phosphate diphosphorylase activity
S101267_RS06500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101267_RS06505	COG2104	thiamine diphosphate biosynthetic process
S101267_RS06515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101267_RS06520	COG0351	phosphomethylpyrimidine kinase
S101267_RS06525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S101267_RS06580	COG0210	DNA helicase
S101267_RS06590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS06600	COG1131	(ABC) transporter
S101267_RS06610	COG2153	protein acetylation
S101267_RS06620	COG2382	esterase
S101267_RS06625	COG0626	cystathionine gamma-synthase activity
S101267_RS06630	COG0626	cystathionine gamma-synthase activity
S101267_RS06640	COG0582	viral genome integration into host DNA
S101267_RS06740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_RS06775	COG0739	heme binding
S101267_RS06775	COG0741	lytic transglycosylase activity
S101267_RS06775	COG1196	nuclear chromosome segregation
S101267_RS06845	COG0582	viral genome integration into host DNA
S101267_RS06855	COG4282	regulation of fungal-type cell wall biogenesis
S101267_RS06880	COG3344	reverse transcriptase
S101267_RS06885	COG5290	Psort location Cytoplasmic, score
S101267_RS06905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101267_RS06960	COG2367	Beta-lactamase
S101267_RS06965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101267_RS06970	COG0477	Major facilitator Superfamily
S101267_RS06975	COG1846	Transcriptional regulator
S101267_RS06990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS06990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS06995	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_RS07000	COG2723	6-phospho-beta-galactosidase activity
S101267_RS07005	COG1349	DNA-binding transcription factor activity
S101267_RS07025	COG1285	pathogenesis
S101267_RS07035	COG2205	protein histidine kinase activity
S101267_RS07045	COG3383	formate dehydrogenase (NAD+) activity
S101267_RS07050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_RS07055	COG0390	transport system, permease component
S101267_RS07060	COG1587	Uroporphyrinogen-III synthase
S101267_RS07070	COG1819	glycosyl
S101267_RS07075	COG2124	cytochrome p450
S101267_RS07080	COG2427	Protein of unknown function (DUF1641)
S101267_RS07085	COG3383	formate dehydrogenase (NAD+) activity
S101267_RS07090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_RS07095	COG0697	spore germination
S101267_RS07100	COG4297	protein containing double-stranded beta helix domain
S101267_RS07110	COG1252	NADH dehydrogenase
S101267_RS07120	COG1609	Transcriptional regulator
S101267_RS07125	COG2721	sulfolactate sulfo-lyase activity
S101267_RS07130	COG0745	RESPONSE REGULATOR receiver
S101267_RS07135	COG5002	protein histidine kinase activity
S101267_RS07140	COG1131	(ABC) transporter
S101267_RS07150	COG0730	response to heat
S101267_RS07155	COG2318	DinB family
S101267_RS07160	COG0457	Tetratricopeptide repeat
S101267_RS07170	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS07170	COG1388	LysM domain
S101267_RS07170	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS07180	COG4195	phage-related replication protein
S101267_RS07185	COG2856	Zn peptidase
S101267_RS07190	COG1396	sequence-specific DNA binding
S101267_RS07200	COG1522	sequence-specific DNA binding
S101267_RS07205	COG1484	DNA-dependent DNA replication
S101267_RS07225	COG1595	DNA-templated transcription, initiation
S101267_RS07230	COG3728	DNA packaging
S101267_RS07230	COG5484	DNA packaging
S101267_RS07235	COG1783	phage Terminase large subunit
S101267_RS07240	COG5518	Phage portal protein
S101267_RS07245	COG0338	D12 class N6 adenine-specific DNA methyltransferase
S101267_RS07250	COG4653	Phage capsid family
S101267_RS07300	COG3953	SLT domain
S101267_RS07300	COG3953	SLT domain
S101267_RS07300	COG3953	SLT domain
S101267_RS07300	COG5412	phage tail tape measure protein
S101267_RS07300	COG5412	phage tail tape measure protein
S101267_RS07300	COG5412	phage tail tape measure protein
S101267_RS07305	COG1652	LysM domain
S101267_RS07310	COG4193	domain, Protein
S101267_RS07320	COG3628	GPW Gp25 family protein
S101267_RS07325	COG3299	homolog of phage Mu protein gp47
S101267_RS07330	COG3778	Protein conserved in bacteria
S101267_RS07385	COG0306	phosphate transporter
S101267_RS07390	COG1392	Phosphate transport regulator
S101267_RS07395	COG0531	amino acid
S101267_RS07400	COG0346	lactoylglutathione lyase activity
S101267_RS07405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101267_RS07410	COG0463	Glycosyl transferase, family 2
S101267_RS07415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_RS07420	COG0477	Major facilitator Superfamily
S101267_RS07425	COG2362	D-Aminopeptidase
S101267_RS07430	COG0601	transmembrane transport
S101267_RS07435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101267_RS07440	COG0444	Belongs to the ABC transporter superfamily
S101267_RS07445	COG4166	transmembrane transport
S101267_RS07450	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101267_RS07455	COG4948	Mandelate Racemase Muconate Lactonizing
S101267_RS07460	COG0791	NLP P60 protein
S101267_RS07465	COG4608	Belongs to the ABC transporter superfamily
S101267_RS07470	COG2706	6-phosphogluconolactonase activity
S101267_RS07475	COG1834	amidinotransferase
S101267_RS07480	COG1607	acyl-coa hydrolase
S101267_RS07485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101267_RS07490	COG2076	Multidrug Resistance protein
S101267_RS07495	COG2076	Multidrug Resistance protein
S101267_RS07500	COG0788	formyltetrahydrofolate deformylase activity
S101267_RS07505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101267_RS07515	COG1764	response to oxidative stress
S101267_RS07520	COG1846	Transcriptional regulator
S101267_RS07525	COG1764	response to oxidative stress
S101267_RS07540	COG0457	Tetratricopeptide repeat
S101267_RS07540	COG0463	Glycosyl transferase, family 2
S101267_RS07550	COG2814	Major facilitator Superfamily
S101267_RS07555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_RS07565	COG1404	Belongs to the peptidase S8 family
S101267_RS07570	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS07575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101267_RS07580	COG1122	ATPase activity
S101267_RS07585	COG4721	ABC-type cobalt transport system, permease component
S101267_RS07590	COG1388	LysM domain
S101267_RS07590	COG3858	chitin binding
S101267_RS07605	COG2239	Acts as a magnesium transporter
S101267_RS07610	COG0789	Transcriptional regulator
S101267_RS07625	COG1846	Transcriptional regulator
S101267_RS07630	COG0726	polysaccharide deacetylase
S101267_RS07635	COG3285	dna ligase
S101267_RS07635	COG1793	dna ligase
S101267_RS07640	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S101267_RS07645	COG3300	MHYT domain
S101267_RS07645	COG5001	Diguanylate cyclase
S101267_RS07650	COG0586	Pfam SNARE associated Golgi protein
S101267_RS07655	COG0861	Integral membrane protein TerC family
S101267_RS07660	COG1191	sigma factor activity
S101267_RS07685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101267_RS07690	COG2323	membrane
S101267_RS07700	COG3594	Acyltransferase
S101267_RS07705	COG5002	protein histidine kinase activity
S101267_RS07710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101267_RS07725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101267_RS07730	COG0436	Aminotransferase
S101267_RS07765	COG3852	Histidine kinase
S101267_RS07770	COG1846	Transcriptional regulator
S101267_RS07775	COG1360	Flagellar Motor Protein
S101267_RS07780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101267_RS07785	COG0542	response to heat
S101267_RS07795	COG3949	Membrane
S101267_RS07810	COG0720	synthase
S101267_RS07815	COG0602	queuosine metabolic process
S101267_RS07830	COG4873	Protein conserved in bacteria
S101267_RS07840	COG3773	Cell wall hydrolase
S101267_RS07845	COG2244	polysaccharide biosynthetic process
S101267_RS07850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS07855	COG2217	Heavy metal translocating P-type atpase
S101267_RS07860	COG0006	proline dipeptidase activity
S101267_RS07865	COG1609	Transcriptional regulator
S101267_RS07870	COG3711	transcriptional antiterminator
S101267_RS07875	COG1263	PTS System
S101267_RS07875	COG2190	(PTS) system
S101267_RS07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS07880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS07885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S101267_RS07895	COG1533	DNA photolyase activity
S101267_RS07900	COG0840	transmembrane signaling receptor activity
S101267_RS07905	COG2084	Dehydrogenase
S101267_RS07915	COG2340	Cysteine-rich secretory protein family
S101267_RS07920	COG0768	penicillin binding
S101267_RS07925	COG4191	Histidine kinase
S101267_RS07930	COG0436	Aminotransferase
S101267_RS07945	COG0784	Response regulator, receiver
S101267_RS07945	COG0835	chemotaxis
S101267_RS07955	COG2814	Major facilitator Superfamily
S101267_RS07960	COG1376	ErfK ybiS ycfS ynhG family protein
S101267_RS07965	COG1408	metallophosphoesterase
S101267_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS07980	COG2200	EAL domain
S101267_RS07985	COG4703	Protein of unknown function (DUF1797)
S101267_RS07990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S101267_RS08000	COG0517	IMP dehydrogenase activity
S101267_RS08005	COG0583	DNA-binding transcription factor activity
S101267_RS08010	COG0716	FMN binding
S101267_RS08020	COG0716	FMN binding
S101267_RS08040	COG0668	transmembrane transport
S101267_RS08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS08070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101267_RS08075	COG0303	'Molybdopterin
S101267_RS08080	COG1763	Mo-molybdopterin cofactor biosynthetic process
S101267_RS08085	COG0314	molybdopterin synthase activity
S101267_RS08090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S101267_RS08100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101267_RS08105	COG1136	(ABC) transporter
S101267_RS08110	COG0577	efflux transmembrane transporter activity
S101267_RS08115	COG1349	DNA-binding transcription factor activity
S101267_RS08120	COG1105	Belongs to the carbohydrate kinase PfkB family
S101267_RS08125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_RS08125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS08125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_RS08130	COG0681	Belongs to the peptidase S26 family
S101267_RS08140	COG0488	(ABC) transporter
S101267_RS08150	COG2309	aminopeptidase activity
S101267_RS08160	COG1077	Cell shape determining protein MreB Mrl
S101267_RS08170	COG2002	toxin-antitoxin pair type II binding
S101267_RS08175	COG3852	Histidine kinase
S101267_RS08180	COG2105	PFAM AIG2 family protein
S101267_RS08180	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S101267_RS08185	COG0569	domain protein
S101267_RS08195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101267_RS08210	COG0561	phosphatase activity
S101267_RS08215	COG0242	peptide deformylase activity
S101267_RS08225	COG0497	DNA recombination
S101267_RS08230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_RS08235	COG0022	dehydrogenase e1 component
S101267_RS08240	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_RS08245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_RS08250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS08265	COG1982	Orn Lys Arg decarboxylase major
S101267_RS08290	COG0483	inositol monophosphate 1-phosphatase activity
S101267_RS08300	COG3227	Zinc metalloprotease (Elastase)
S101267_RS08325	COG1217	gtp-binding protein TYPA
S101267_RS08335	COG4896	Protein conserved in bacteria
S101267_RS08345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S101267_RS08350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101267_RS08355	COG2066	Belongs to the glutaminase family
S101267_RS08365	COG0772	Belongs to the SEDS family
S101267_RS08370	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
S101267_RS08385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101267_RS08385	COG2010	Cytochrome c
S101267_RS08390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101267_RS08395	COG1845	cytochrome c oxidase, subunit III
S101267_RS08400	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101267_RS08405	COG3336	cytochrome c oxidase
S101267_RS08415	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S101267_RS08420	COG2340	Cysteine-rich secretory protein family
S101267_RS08435	COG3679	Belongs to the UPF0342 family
S101267_RS08445	COG0742	ribosomal rna small subunit methyltransferase
S101267_RS08455	COG3314	Sporulation integral membrane protein YlbJ
S101267_RS08460	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101267_RS08465	COG3480	Lon protease (S16) C-terminal proteolytic domain
S101267_RS08475	COG1399	metal-binding, possibly nucleic acid-binding protein
S101267_RS08495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101267_RS08515	COG4839	cell division protein FtsL
S101267_RS08520	COG0768	penicillin binding
S101267_RS08525	COG0768	penicillin binding
S101267_RS08545	COG0772	Belongs to the SEDS family
S101267_RS08560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S101267_RS08565	COG0849	cell division
S101267_RS08570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S101267_RS08575	COG1404	Belongs to the peptidase S8 family
S101267_RS08575	COG4412	M6 family metalloprotease domain protein
S101267_RS08585	COG1191	sigma factor activity
S101267_RS08590	COG1191	sigma factor activity
S101267_RS08595	COG1119	ATPase activity
S101267_RS08600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_RS08605	COG1873	PFAM PRC-barrel domain
S101267_RS08610	COG1496	oxidoreductase activity
S101267_RS08615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S101267_RS08625	COG0762	integral membrane protein
S101267_RS08630	COG2302	S4 RNA-binding domain
S101267_RS08635	COG3599	regulation of cell shape
S101267_RS08645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S101267_RS08650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_RS08660	COG0564	pseudouridine synthase activity
S101267_RS08670	COG2233	PERMEase
S101267_RS08680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101267_RS08685	COG0505	Belongs to the CarA family
S101267_RS08690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101267_RS08705	COG0284	orotidine-5'-phosphate decarboxylase activity
S101267_RS08710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S101267_RS08720	COG0306	phosphate transporter
S101267_RS08735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101267_RS08740	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
S101267_RS08745	COG1648	precorrin-2 dehydrogenase activity
S101267_RS08755	COG1293	RNA-binding protein homologous to eukaryotic snRNP
S101267_RS08760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101267_RS08765	COG1561	YicC-like family, N-terminal region
S101267_RS08775	COG0194	GDP metabolic process
S101267_RS08785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101267_RS08790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101267_RS08795	COG0242	peptide deformylase activity
S101267_RS08805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S101267_RS08805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101267_RS08815	COG0631	protein serine/threonine phosphatase activity
S101267_RS08820	COG0515	serine threonine protein kinase
S101267_RS08820	COG2815	serine threonine protein kinase
S101267_RS08830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S101267_RS08835	COG1564	THIamine pyrophosphokinase
S101267_RS08850	COG1302	Protein conserved in bacteria
S101267_RS08855	COG1461	Dihydroxyacetone kinase
S101267_RS08860	COG1760	l-serine dehydratase
S101267_RS08865	COG1760	l-serine dehydratase
S101267_RS08870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S101267_RS08885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S101267_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS08905	COG1196	nuclear chromosome segregation
S101267_RS08910	COG0552	protein localization to endoplasmic reticulum
S101267_RS08920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S101267_RS08930	COG1837	Belongs to the UPF0109 family
S101267_RS08955	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101267_RS08970	COG2257	FlhB HrpN YscU SpaS Family
S101267_RS08980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S101267_RS08985	COG0758	DNA mediated transformation
S101267_RS08990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101267_RS09000	COG4974	Belongs to the 'phage' integrase family
S101267_RS09020	COG1815	bacterial-type flagellum-dependent cell motility
S101267_RS09025	COG1558	bacterial-type flagellum-dependent cell motility
S101267_RS09030	COG1677	Flagellar hook-basal body complex protein FliE
S101267_RS09035	COG1766	The M ring may be actively involved in energy transduction
S101267_RS09040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_RS09045	COG1317	bacterial-type flagellum organization
S101267_RS09050	COG1157	protein secretion by the type III secretion system
S101267_RS09055	COG2882	bacterial-type flagellum organization
S101267_RS09060	COG3334	PFAM MgtE intracellular
S101267_RS09065	COG3144	bacterial-type flagellum assembly
S101267_RS09070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S101267_RS09075	COG4786	Flagellar basal body rod
S101267_RS09080	COG1582	Flagellar protein (FlbD)
S101267_RS09085	COG1580	Controls the rotational direction of flagella during chemotaxis
S101267_RS09090	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_RS09095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101267_RS09095	COG1776	CheC inhibitor of MCP methylation
S101267_RS09100	COG2201	protein-glutamate methylesterase activity
S101267_RS09105	COG3190	flagellar
S101267_RS09110	COG1338	Plays a role in the flagellum-specific transport system
S101267_RS09115	COG1987	bacterial-type flagellum assembly
S101267_RS09120	COG1684	flagellar biosynthetic protein fliR
S101267_RS09125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101267_RS09130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101267_RS09135	COG1419	protein localization to endoplasmic reticulum
S101267_RS09140	COG0455	bacterial-type flagellum organization
S101267_RS09145	COG2201	protein-glutamate methylesterase activity
S101267_RS09150	COG0643	Histidine kinase
S101267_RS09150	COG2198	Histidine kinase
S101267_RS09155	COG0835	chemotaxis
S101267_RS09160	COG1776	CheC inhibitor of MCP methylation
S101267_RS09170	COG1191	sigma factor activity
S101267_RS09200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S101267_RS09205	COG4589	Belongs to the CDS family
S101267_RS09215	COG0750	zinc metalloprotease
S101267_RS09225	COG2176	DNA-directed DNA polymerase activity
S101267_RS09235	COG0195	Participates in both transcription termination and antitermination
S101267_RS09240	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S101267_RS09245	COG1358	cellular component organization or biogenesis
S101267_RS09255	COG1550	Protein conserved in bacteria
S101267_RS09270	COG0196	riboflavin kinase activity
S101267_RS09285	COG0726	polysaccharide deacetylase
S101267_RS09290	COG0612	Peptidase, M16
S101267_RS09295	COG1873	PFAM PRC-barrel domain
S101267_RS09300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101267_RS09305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101267_RS09310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S101267_RS09315	COG0527	aspartate kinase activity
S101267_RS09325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101267_RS09330	COG0740	serine-type endopeptidase activity
S101267_RS09340	COG4980	gas vesicle protein
S101267_RS09340	COG1674	ftsk spoiiie
S101267_RS09345	COG2188	Transcriptional regulator
S101267_RS09350	COG2814	Major facilitator Superfamily
S101267_RS09355	COG1846	Transcriptional regulator
S101267_RS09360	COG1033	growth of symbiont in host cell
S101267_RS09360	COG2409	Drug exporters of the RND superfamily
S101267_RS09365	COG0612	Peptidase, M16
S101267_RS09370	COG0612	Peptidase, M16
S101267_RS09375	COG0300	oxidoreductase activity
S101267_RS09390	COG1426	Protein conserved in bacteria
S101267_RS09395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S101267_RS09410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101267_RS09420	COG1692	metallophosphoesterase
S101267_RS09425	COG2359	stage V sporulation protein S
S101267_RS09445	COG4550	Control of competence regulator ComK, YlbF/YmcA
S101267_RS09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_RS09490	COG3425	synthase
S101267_RS09495	COG1024	Enoyl-CoA hydratase
S101267_RS09500	COG1024	Enoyl-CoA hydratase
S101267_RS09505	COG0300	oxidoreductase activity
S101267_RS09505	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_RS09505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS09505	COG3321	synthase
S101267_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS09510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_RS09510	COG3321	synthase
S101267_RS09510	COG4221	oxidoreductase activity
S101267_RS09510	COG0300	oxidoreductase activity
S101267_RS09515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS09515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_RS09515	COG3321	synthase
S101267_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS09515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS09515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_RS09515	COG3321	synthase
S101267_RS09520	COG4221	oxidoreductase activity
S101267_RS09520	COG3321	synthase
S101267_RS09520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS09525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101267_RS09525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
S101267_RS09525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101267_RS09525	COG3321	synthase
S101267_RS09530	COG2124	cytochrome p450
S101267_RS09535	COG3209	COG3209 Rhs family protein
S101267_RS09540	COG3619	membrane
S101267_RS09550	COG1404	Belongs to the peptidase S8 family
S101267_RS09560	COG4195	phage-related replication protein
S101267_RS09565	COG1764	response to oxidative stress
S101267_RS09575	COG2076	Multidrug Resistance protein
S101267_RS09615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_RS09620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_RS09625	COG4112	unkown
S101267_RS09635	COG0464	growth
S101267_RS09640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S101267_RS09645	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S101267_RS09650	COG0789	Transcriptional regulator
S101267_RS09655	COG0174	glutamine synthetase
S101267_RS09660	COG4974	Belongs to the 'phage' integrase family
S101267_RS09680	COG3645	SOS response
S101267_RS09680	COG3646	Phage regulatory protein
S101267_RS09720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS09720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS09830	COG5412	phage tail tape measure protein
S101267_RS09830	COG3953	SLT domain
S101267_RS09840	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_RS09845	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS09865	COG4824	toxin secretion phage lysis holin
S101267_RS09870	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS09870	COG1388	LysM domain
S101267_RS09870	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS09905	COG0726	polysaccharide deacetylase
S101267_RS09910	COG2124	cytochrome p450
S101267_RS09915	COG2211	Major facilitator Superfamily
S101267_RS09920	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_RS09935	COG1070	Carbohydrate kinase
S101267_RS09945	COG3848	Pyruvate phosphate dikinase
S101267_RS09945	COG0574	Belongs to the PEP-utilizing enzyme family
S101267_RS09955	COG1063	alcohol dehydrogenase
S101267_RS09965	COG0457	Tetratricopeptide repeat
S101267_RS10010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS10025	COG2323	membrane
S101267_RS10035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS10040	COG2323	membrane
S101267_RS10050	COG2318	DinB family
S101267_RS10055	COG1064	alcohol dehydrogenase
S101267_RS10080	COG0456	acetyltransferase
S101267_RS10115	COG3397	chitin binding
S101267_RS10130	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS10135	COG2314	TM2 domain
S101267_RS10140	COG0756	dUTP diphosphatase activity
S101267_RS10150	COG4195	phage-related replication protein
S101267_RS10180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_RS10190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S101267_RS10210	COG0785	Cytochrome C biogenesis protein
S101267_RS10215	COG2201	protein-glutamate methylesterase activity
S101267_RS10220	COG4846	Membrane protein involved in cytochrome C biogenesis
S101267_RS10230	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_RS10245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S101267_RS10250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS10270	COG0824	Thioesterase
S101267_RS10280	COG4841	protein insertion into membrane
S101267_RS10290	COG1832	CoA-binding protein
S101267_RS10295	COG0187	DNA topoisomerase II activity
S101267_RS10300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101267_RS10310	COG1115	amino acid carrier protein
S101267_RS10340	COG2205	protein histidine kinase activity
S101267_RS10345	COG0745	RESPONSE REGULATOR receiver
S101267_RS10355	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_RS10385	COG2721	sulfolactate sulfo-lyase activity
S101267_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS10395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101267_RS10400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101267_RS10405	COG2124	cytochrome p450
S101267_RS10425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_RS10435	COG2246	polysaccharide biosynthetic process
S101267_RS10440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101267_RS10445	COG0586	Pfam SNARE associated Golgi protein
S101267_RS10450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101267_RS10455	COG1024	Enoyl-CoA hydratase
S101267_RS10460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101267_RS10465	COG0511	ligase activity, forming carbon-carbon bonds
S101267_RS10470	COG0439	Biotin carboxylase
S101267_RS10480	COG1960	acyl-CoA dehydrogenase activity
S101267_RS10485	COG1649	PFAM Uncharacterised BCR, COG1649
S101267_RS10495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS10495	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101267_RS10500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS10510	COG2027	D-alanyl-D-alanine carboxypeptidase
S101267_RS10515	COG2017	converts alpha-aldose to the beta-anomer
S101267_RS10520	COG0534	Mate efflux family protein
S101267_RS10535	COG0582	viral genome integration into host DNA
S101267_RS10540	COG0166	Belongs to the GPI family
S101267_RS10545	COG0405	Gamma-glutamyltransferase
S101267_RS10550	COG2814	Major facilitator Superfamily
S101267_RS10555	COG0640	Transcriptional regulator
S101267_RS10560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101267_RS10565	COG0493	'glutamate synthase
S101267_RS10570	COG0069	glutamate synthase activity
S101267_RS10570	COG0070	glutamate synthase
S101267_RS10570	COG0067	glutamate synthase
S101267_RS10575	COG0583	DNA-binding transcription factor activity
S101267_RS10580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101267_RS10595	COG0300	oxidoreductase activity
S101267_RS10600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101267_RS10610	COG2323	membrane
S101267_RS10615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS10625	COG2323	membrane
S101267_RS10640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS10680	COG2814	Major facilitator Superfamily
S101267_RS10685	COG1070	Carbohydrate kinase
S101267_RS10695	COG0243	molybdopterin cofactor binding
S101267_RS10725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_RS10730	COG0662	Cupin 2, conserved barrel domain protein
S101267_RS10730	COG2207	Transcriptional regulator
S101267_RS10735	COG1309	transcriptional regulator
S101267_RS10740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS10750	COG0640	Transcriptional regulator
S101267_RS10755	COG0741	lytic transglycosylase activity
S101267_RS10760	COG2322	membrane
S101267_RS10775	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101267_RS10785	COG3584	3D domain protein
S101267_RS10785	COG1388	LysM domain
S101267_RS10790	COG0514	ATP-dependent DNA helicase (RecQ)
S101267_RS10800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101267_RS10805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_RS10820	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_RS10850	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS10855	COG1657	PFAM Prenyltransferase squalene oxidase
S101267_RS10860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101267_RS10865	COG0733	neurotransmitter:sodium symporter activity
S101267_RS10870	COG0385	Bile acid
S101267_RS10875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS10880	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_RS10890	COG4548	von Willebrand factor, type A
S101267_RS10895	COG0714	Associated with various cellular activities
S101267_RS10900	COG2032	superoxide dismutase activity
S101267_RS10905	COG1388	LysM domain
S101267_RS10905	COG0791	NLP P60 protein
S101267_RS10910	COG1819	glycosyl
S101267_RS10915	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101267_RS10920	COG0534	Mate efflux family protein
S101267_RS10925	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS10930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_RS10935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_RS10945	COG2962	Rard protein
S101267_RS10960	COG1942	4-Oxalocrotonate Tautomerase
S101267_RS10970	COG1733	regulation of RNA biosynthetic process
S101267_RS10975	COG0778	Nitroreductase
S101267_RS10985	COG0346	lactoylglutathione lyase activity
S101267_RS10995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101267_RS11005	COG2723	6-phospho-beta-galactosidase activity
S101267_RS11010	COG2188	Transcriptional regulator
S101267_RS11015	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS11015	COG0793	Belongs to the peptidase S41A family
S101267_RS11020	COG2226	methyltransferase
S101267_RS11030	COG1876	peptidase activity
S101267_RS11050	COG0671	phosphoesterase, PA-phosphatase related
S101267_RS11070	COG0346	lactoylglutathione lyase activity
S101267_RS11085	COG1509	lysine 2,3-aminomutase activity
S101267_RS11095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_RS11100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101267_RS11105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101267_RS11110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101267_RS11120	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S101267_RS11130	COG0456	acetyltransferase
S101267_RS11135	COG0463	Glycosyl transferase, family 2
S101267_RS11150	COG4641	Protein conserved in bacteria
S101267_RS11160	COG1086	Polysaccharide biosynthesis protein
S101267_RS11190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_RS11195	COG1086	Polysaccharide biosynthesis protein
S101267_RS11210	COG1846	Transcriptional regulator
S101267_RS11215	COG4698	Protein conserved in bacteria
S101267_RS11220	COG2755	lipolytic protein G-D-S-L family
S101267_RS11225	COG1999	signal sequence binding
S101267_RS11235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101267_RS11240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101267_RS11245	COG1272	protein, Hemolysin III
S101267_RS11250	COG0204	Acyl-transferase
S101267_RS11255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101267_RS11260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
S101267_RS11270	COG2521	methyltransferase
S101267_RS11270	COG2136	Putative SAM-dependent methyltransferase
S101267_RS11285	COG1413	lyase activity
S101267_RS11290	COG1418	mRNA catabolic process
S101267_RS11295	COG0386	Belongs to the glutathione peroxidase family
S101267_RS11305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101267_RS11310	COG1278	Cold shock
S101267_RS11330	COG0328	RNA-DNA hybrid ribonuclease activity
S101267_RS11335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S101267_RS11340	COG0328	RNA-DNA hybrid ribonuclease activity
S101267_RS11350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS11365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101267_RS11370	COG1755	Isoprenylcysteine carboxyl methyltransferase
S101267_RS11375	COG3424	synthase
S101267_RS11400	COG2233	PERMEase
S101267_RS11410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S101267_RS11415	COG1199	ATP-dependent helicase activity
S101267_RS11435	COG0116	Belongs to the methyltransferase superfamily
S101267_RS11460	COG3359	exonuclease
S101267_RS11465	COG1205	dead DEAH box helicase
S101267_RS11465	COG1111	helicase
S101267_RS11470	COG2190	(PTS) system
S101267_RS11475	COG0071	Belongs to the small heat shock protein (HSP20) family
S101267_RS11515	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101267_RS11515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_RS11525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S101267_RS11530	COG3935	DnaD domain protein
S101267_RS11540	COG0436	Aminotransferase
S101267_RS11545	COG5353	protein conserved in bacteria
S101267_RS11555	COG1199	ATP-dependent helicase activity
S101267_RS11555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S101267_RS11585	COG0438	transferase activity, transferring glycosyl groups
S101267_RS11590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_RS11605	COG1694	Mazg nucleotide pyrophosphohydrolase
S101267_RS11610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS11615	COG2140	Oxalate decarboxylase
S101267_RS11625	COG4347	Protein of unknown function (DUF1405)
S101267_RS11630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101267_RS11630	COG2010	Cytochrome c
S101267_RS11635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101267_RS11640	COG0723	plastoquinol--plastocyanin reductase activity
S101267_RS11655	COG0457	Tetratricopeptide repeat
S101267_RS11665	COG0287	Prephenate dehydrogenase
S101267_RS11700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101267_RS11705	COG4401	Chorismate mutase type I
S101267_RS11720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
S101267_RS11725	COG0105	UTP biosynthetic process
S101267_RS11730	COG0142	geranyltranstransferase activity
S101267_RS11740	COG0142	geranyltranstransferase activity
S101267_RS11755	COG0776	regulation of translation
S101267_RS11760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101267_RS11800	COG0539	negative regulation of cytoplasmic translation
S101267_RS11815	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S101267_RS11820	COG2959	enzyme of heme biosynthesis
S101267_RS11825	COG3773	Cell wall hydrolase
S101267_RS11825	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS11830	COG2339	peptidase activity
S101267_RS11835	COG0492	ferredoxin-NADP+ reductase activity
S101267_RS11840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_RS11845	COG4862	establishment of competence for transformation
S101267_RS11850	COG1408	metallophosphoesterase
S101267_RS11860	COG1388	LysM domain
S101267_RS11865	COG1266	CAAX protease self-immunity
S101267_RS11870	COG0514	ATP-dependent DNA helicase (RecQ)
S101267_RS11875	COG4955	Helix-turn-helix domain
S101267_RS11880	COG1141	Ferredoxin
S101267_RS11885	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S101267_RS11890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101267_RS11900	COG1595	DNA-templated transcription, initiation
S101267_RS11905	COG5002	protein histidine kinase activity
S101267_RS11910	COG0745	RESPONSE REGULATOR receiver
S101267_RS11915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101267_RS11920	COG1333	cytochrome c biogenesis protein
S101267_RS11925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS11930	COG1187	pseudouridine synthase activity
S101267_RS11935	COG0700	Nucleoside recognition
S101267_RS11940	COG2715	membrane protein required for spore maturation
S101267_RS11945	COG1686	Belongs to the peptidase S11 family
S101267_RS11970	COG1547	Domain of unknown function (DUF309)
S101267_RS11980	COG0456	acetyltransferase
S101267_RS11985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
S101267_RS11990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101267_RS11990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101267_RS11995	COG0307	riboflavin synthase, alpha
S101267_RS12000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101267_RS12000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101267_RS12010	COG0681	Belongs to the peptidase S26 family
S101267_RS12020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101267_RS12025	COG4086	secreted protein
S101267_RS12030	COG0019	diaminopimelate decarboxylase activity
S101267_RS12035	COG0697	spore germination
S101267_RS12050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS12070	COG1191	sigma factor activity
S101267_RS12080	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS12085	COG1686	Belongs to the peptidase S11 family
S101267_RS12090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S101267_RS12095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S101267_RS12100	COG4974	Belongs to the 'phage' integrase family
S101267_RS12110	COG0735	belongs to the Fur family
S101267_RS12115	COG1300	Membrane
S101267_RS12130	COG0281	malic enzyme
S101267_RS12135	COG1757	Na H antiporter
S101267_RS12140	COG1027	Aspartate ammonia-lyase
S101267_RS12145	COG0252	asparaginase activity
S101267_RS12150	COG1396	sequence-specific DNA binding
S101267_RS12155	COG1379	DNA repair
S101267_RS12160	COG0494	nUDIX hydrolase
S101267_RS12170	COG0667	Aldo Keto reductase
S101267_RS12190	COG4918	Iron-sulphur cluster biosynthesis
S101267_RS12195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
S101267_RS12195	COG0456	acetyltransferase
S101267_RS12200	COG0456	acetyltransferase
S101267_RS12205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101267_RS12220	COG0628	permease
S101267_RS12235	COG3048	D-serine ammonia-lyase activity
S101267_RS12240	COG0300	oxidoreductase activity
S101267_RS12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS12250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101267_RS12275	COG0596	Alpha beta hydrolase
S101267_RS12290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S101267_RS12295	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101267_RS12310	COG0706	membrane insertase activity
S101267_RS12315	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101267_RS12320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101267_RS12325	COG0346	lactoylglutathione lyase activity
S101267_RS12330	COG1376	ErfK ybiS ycfS ynhG family protein
S101267_RS12335	COG4129	membrane
S101267_RS12340	COG1126	abc transporter atp-binding protein
S101267_RS12345	COG0765	amino acid transport
S101267_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS12360	COG1597	lipid kinase activity
S101267_RS12365	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101267_RS12370	COG0022	dehydrogenase e1 component
S101267_RS12375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101267_RS12380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101267_RS12385	COG3426	butyrate kinase activity
S101267_RS12390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_RS12395	COG0280	phosphate acetyltransferase
S101267_RS12400	COG3290	protein histidine kinase activity
S101267_RS12400	COG3829	transcription factor binding
S101267_RS12410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S101267_RS12415	COG2079	MmgE PrpD family protein
S101267_RS12420	COG0372	Belongs to the citrate synthase family
S101267_RS12425	COG1960	acyl-CoA dehydrogenase activity
S101267_RS12435	COG0183	Belongs to the thiolase family
S101267_RS12440	COG0584	glycerophosphoryl diester phosphodiesterase
S101267_RS12445	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS12465	COG1902	pentaerythritol trinitrate reductase activity
S101267_RS12480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101267_RS12485	COG0745	RESPONSE REGULATOR receiver
S101267_RS12490	COG0750	zinc metalloprotease
S101267_RS12495	COG0497	DNA recombination
S101267_RS12505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S101267_RS12515	COG0142	geranyltranstransferase activity
S101267_RS12525	COG1570	exodeoxyribonuclease VII activity
S101267_RS12540	COG1302	Protein conserved in bacteria
S101267_RS12545	COG0439	Biotin carboxylase
S101267_RS12550	COG0511	ligase activity, forming carbon-carbon bonds
S101267_RS12590	COG3854	ATPases associated with a variety of cellular activities
S101267_RS12605	COG0006	proline dipeptidase activity
S101267_RS12615	COG3872	metal-dependent enzyme
S101267_RS12625	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101267_RS12640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101267_RS12660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101267_RS12675	COG1396	sequence-specific DNA binding
S101267_RS12685	COG0681	Belongs to the peptidase S26 family
S101267_RS12710	COG4940	Competence protein ComGF
S101267_RS12720	COG4970	Tfp pilus assembly protein FimT
S101267_RS12725	COG4537	Required for transformation and DNA binding
S101267_RS12730	COG1459	type II secretion system
S101267_RS12735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S101267_RS12740	COG0598	Magnesium transport protein CorA
S101267_RS12745	COG1253	flavin adenine dinucleotide binding
S101267_RS12750	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS12760	COG1393	Belongs to the ArsC family
S101267_RS12770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS12780	COG0011	TIGRFAM Protein of
S101267_RS12790	COG2866	Carboxypeptidase
S101267_RS12795	COG1940	carbohydrate kinase activity
S101267_RS12800	COG4483	Protein conserved in bacteria
S101267_RS12805	COG1757	Na H antiporter
S101267_RS12815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S101267_RS12830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101267_RS12835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_RS12840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101267_RS12845	COG0581	inorganic phosphate transmembrane transporter activity
S101267_RS12850	COG0573	inorganic phosphate transmembrane transporter activity
S101267_RS12855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S101267_RS12860	COG0768	penicillin binding
S101267_RS12865	COG0477	Major facilitator Superfamily
S101267_RS12870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101267_RS12875	COG2839	Protein conserved in bacteria
S101267_RS12880	COG5521	maltodextrose utilization protein MalA
S101267_RS12885	COG1388	LysM domain
S101267_RS12895	COG4709	membrane
S101267_RS12900	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101267_RS12905	COG0735	belongs to the Fur family
S101267_RS12910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS12925	COG0513	Belongs to the DEAD box helicase family
S101267_RS12940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S101267_RS12945	COG2384	SAM-dependent methyltransferase
S101267_RS12950	COG2010	Cytochrome c
S101267_RS12955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S101267_RS12960	COG0358	DNA primase activity
S101267_RS12975	COG0517	IMP dehydrogenase activity
S101267_RS12980	COG0751	glycine-tRNA ligase activity
S101267_RS13000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S101267_RS13005	COG0295	cytidine deaminase activity
S101267_RS13010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S101267_RS13020	COG1480	7TM receptor with intracellular HD hydrolase
S101267_RS13025	COG1702	phosphate starvation-inducible protein PhoH
S101267_RS13030	COG0561	phosphatase activity
S101267_RS13045	COG4864	UPF0365 protein
S101267_RS13050	COG1030	water channel activity
S101267_RS13055	COG1610	YqeY-like protein
S101267_RS13065	COG1283	sodium-dependent phosphate transmembrane transporter activity
S101267_RS13070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101267_RS13075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S101267_RS13105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101267_RS13120	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS13135	COG1466	dna polymerase III delta subunit
S101267_RS13145	COG2333	competence protein COMEC
S101267_RS13145	COG0658	competence protein
S101267_RS13150	COG2131	deaminase
S101267_RS13155	COG1596	polysaccharide export
S101267_RS13155	COG1555	photosystem II stabilization
S101267_RS13160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101267_RS13165	COG2226	methyltransferase
S101267_RS13170	COG0799	negative regulation of ribosome biogenesis
S101267_RS13175	COG1713	HD superfamily hydrolase involved in NAD metabolism
S101267_RS13185	COG1534	Rna-binding protein
S101267_RS13190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101267_RS13195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101267_RS13200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S101267_RS13210	COG2755	lipolytic protein G-D-S-L family
S101267_RS13220	COG0398	Pfam SNARE associated Golgi protein
S101267_RS13240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101267_RS13285	COG0512	Glutamine amidotransferase of anthranilate synthase
S101267_RS13310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
S101267_RS13325	COG2378	regulation of single-species biofilm formation
S101267_RS13330	COG0693	protein deglycase activity
S101267_RS13360	COG0457	Tetratricopeptide repeat
S101267_RS13380	COG3628	GPW Gp25 family protein
S101267_RS13385	COG1794	racemase activity, acting on amino acids and derivatives
S101267_RS13395	COG1733	regulation of RNA biosynthetic process
S101267_RS13400	COG0656	L-ascorbic acid biosynthetic process
S101267_RS13410	COG4653	Phage capsid family
S101267_RS13440	COG0563	adenylate kinase activity
S101267_RS13450	COG2814	Major facilitator Superfamily
S101267_RS13455	COG0456	acetyltransferase
S101267_RS13460	COG2318	DinB family
S101267_RS13470	COG0561	phosphatase activity
S101267_RS13485	COG1482	cell wall glycoprotein biosynthetic process
S101267_RS13490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_RS13490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS13490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101267_RS13495	COG3711	transcriptional antiterminator
S101267_RS13495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS13505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101267_RS13510	COG0583	DNA-binding transcription factor activity
S101267_RS13515	COG2814	Major facilitator Superfamily
S101267_RS13520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_RS13520	COG2124	cytochrome p450
S101267_RS13525	COG1309	transcriptional regulator
S101267_RS13530	COG2226	methyltransferase
S101267_RS13545	COG2116	formate transmembrane transporter activity
S101267_RS13550	COG5609	conserved protein (DUF2294)
S101267_RS13555	COG3383	formate dehydrogenase (NAD+) activity
S101267_RS13560	COG2427	Protein of unknown function (DUF1641)
S101267_RS13570	COG0626	cystathionine gamma-synthase activity
S101267_RS13575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_RS13600	COG0768	penicillin binding
S101267_RS13615	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS13615	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS13620	COG4824	toxin secretion phage lysis holin
S101267_RS13640	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS13645	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_RS13655	COG3953	SLT domain
S101267_RS13655	COG5412	phage tail tape measure protein
S101267_RS13740	COG4980	gas vesicle protein
S101267_RS13740	COG1674	ftsk spoiiie
S101267_RS13745	COG0582	viral genome integration into host DNA
S101267_RS13750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S101267_RS13845	COG0826	peptidase U32
S101267_RS13850	COG0826	peptidase U32
S101267_RS13855	COG4122	O-methyltransferase activity
S101267_RS13860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101267_RS13885	COG0628	permease
S101267_RS13890	COG1126	abc transporter atp-binding protein
S101267_RS13895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS13900	COG0765	amino acid transport
S101267_RS13905	COG0765	amino acid transport
S101267_RS13920	COG3881	PFAM PRC-barrel domain
S101267_RS13925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S101267_RS13930	COG0457	Tetratricopeptide repeat
S101267_RS13940	COG1104	cysteine desulfurase activity
S101267_RS13945	COG1959	2 iron, 2 sulfur cluster binding
S101267_RS13950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S101267_RS13955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S101267_RS13985	COG3103	Sh3 type 3 domain protein
S101267_RS13985	COG4991	sh3 domain protein
S101267_RS13985	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS13990	COG1490	D-aminoacyl-tRNA deacylase activity
S101267_RS13995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S101267_RS14005	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
S101267_RS14005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
S101267_RS14010	COG5416	Lipopolysaccharide assembly protein A domain
S101267_RS14015	COG0490	domain, Protein
S101267_RS14020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101267_RS14020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101267_RS14030	COG2244	polysaccharide biosynthetic process
S101267_RS14035	COG2323	membrane
S101267_RS14045	COG1862	Preprotein translocase
S101267_RS14085	COG1388	LysM domain
S101267_RS14095	COG0157	Belongs to the NadC ModD family
S101267_RS14100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S101267_RS14105	COG1104	cysteine desulfurase activity
S101267_RS14110	COG1827	regulation of RNA biosynthetic process
S101267_RS14115	COG0077	Prephenate dehydratase
S101267_RS14130	COG3290	protein histidine kinase activity
S101267_RS14135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S101267_RS14140	COG2868	ribosomal protein
S101267_RS14150	COG1994	Peptidase M50
S101267_RS14155	COG0739	heme binding
S101267_RS14160	COG2894	cell division
S101267_RS14165	COG0850	regulation of cytokinetic process
S101267_RS14170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S101267_RS14180	COG1077	Cell shape determining protein MreB Mrl
S101267_RS14200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
S101267_RS14205	COG0285	dihydrofolate synthase activity
S101267_RS14210	COG0525	valine-tRNA ligase activity
S101267_RS14220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_RS14225	COG1388	LysM domain
S101267_RS14235	COG0113	porphobilinogen synthase activity
S101267_RS14240	COG1587	Uroporphyrinogen-III synthase
S101267_RS14250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101267_RS14270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S101267_RS14275	COG1067	ATP-dependent peptidase activity
S101267_RS14275	COG0470	DNA polymerase III
S101267_RS14290	COG0457	Tetratricopeptide repeat
S101267_RS14290	COG1477	protein flavinylation
S101267_RS14305	COG0473	3-isopropylmalate dehydrogenase activity
S101267_RS14320	COG0440	acetolactate synthase activity
S101267_RS14325	COG0028	Belongs to the TPP enzyme family
S101267_RS14350	COG0622	Phosphoesterase
S101267_RS14355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
S101267_RS14365	COG5401	PFAM Sporulation and spore germination
S101267_RS14375	COG1846	Transcriptional regulator
S101267_RS14380	COG2197	response regulator
S101267_RS14385	COG0824	Thioesterase
S101267_RS14390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S101267_RS14395	COG1053	succinate dehydrogenase
S101267_RS14400	COG2009	succinate dehydrogenase
S101267_RS14405	COG1719	4-vinyl reductase, 4VR
S101267_RS14410	COG0527	aspartate kinase activity
S101267_RS14420	COG3118	belongs to the thioredoxin family
S101267_RS14425	COG3534	alpha-L-arabinofuranosidase
S101267_RS14430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
S101267_RS14435	COG2086	electron transfer activity
S101267_RS14440	COG1024	Enoyl-CoA hydratase
S101267_RS14445	COG1309	transcriptional regulator
S101267_RS14450	COG0318	PFAM AMP-dependent synthetase and ligase
S101267_RS14460	COG3766	membrane
S101267_RS14470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101267_RS14470	COG1796	DNA polymerase
S101267_RS14475	COG1286	toxin biosynthetic process
S101267_RS14490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_RS14490	COG0072	phenylalanine-tRNA ligase activity
S101267_RS14495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S101267_RS14500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101267_RS14510	COG3835	regulator
S101267_RS14515	COG0277	FAD linked oxidase domain protein
S101267_RS14520	COG0247	lactate metabolic process
S101267_RS14525	COG1966	Carbon starvation protein
S101267_RS14530	COG3534	alpha-L-arabinofuranosidase
S101267_RS14535	COG0395	ABC-type sugar transport system, permease component
S101267_RS14540	COG1175	transmembrane transport
S101267_RS14545	COG1653	transport
S101267_RS14555	COG0647	UMP catabolic process
S101267_RS14560	COG0235	Class ii aldolase
S101267_RS14565	COG1069	ribulokinase activity
S101267_RS14570	COG2160	L-arabinose isomerase activity
S101267_RS14575	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_RS14580	COG1363	Peptidase, m42
S101267_RS14590	COG3326	Membrane
S101267_RS14595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
S101267_RS14605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S101267_RS14610	COG1346	cytolysis
S101267_RS14615	COG1380	Effector of murein hydrolase LrgA
S101267_RS14620	COG3279	Response regulator of the LytR AlgR family
S101267_RS14625	COG3275	phosphorelay sensor kinase activity
S101267_RS14630	COG1011	Hydrolase
S101267_RS14645	COG0398	Pfam SNARE associated Golgi protein
S101267_RS14650	COG1484	DNA-dependent DNA replication
S101267_RS14655	COG3611	Membrane attachment protein
S101267_RS14670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101267_RS14675	COG1733	regulation of RNA biosynthetic process
S101267_RS14680	COG2814	Major facilitator Superfamily
S101267_RS14685	COG0656	L-ascorbic acid biosynthetic process
S101267_RS14690	COG0237	dephospho-CoA kinase activity
S101267_RS14695	COG1971	Probably functions as a manganese efflux pump
S101267_RS14700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S101267_RS14705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS14705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS14710	COG5002	protein histidine kinase activity
S101267_RS14715	COG0745	RESPONSE REGULATOR receiver
S101267_RS14725	COG0538	isocitrate dehydrogenase activity
S101267_RS14730	COG0372	Belongs to the citrate synthase family
S101267_RS14740	COG0628	permease
S101267_RS14745	COG3030	protein affecting phage T7 exclusion by the F plasmid
S101267_RS14750	COG0469	pyruvate kinase activity
S101267_RS14770	COG0281	malic enzyme
S101267_RS14775	COG0587	DNA-directed DNA polymerase activity
S101267_RS14795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S101267_RS14805	COG4109	DRTGG domain
S101267_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS14835	COG0521	Mo-molybdopterin cofactor biosynthetic process
S101267_RS14845	COG0827	DNA restriction-modification system
S101267_RS14850	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S101267_RS14855	COG3874	Sporulation protein YtfJ
S101267_RS14865	COG1714	RDD family
S101267_RS14870	COG0616	signal peptide processing
S101267_RS14875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101267_RS14880	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S101267_RS14885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101267_RS14900	COG1104	cysteine desulfurase activity
S101267_RS14905	COG1114	Component of the transport system for branched-chain amino acids
S101267_RS14915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101267_RS14920	COG1309	transcriptional regulator
S101267_RS14925	COG1956	GAF domain-containing protein
S101267_RS14930	COG2199	diguanylate cyclase activity
S101267_RS14930	COG2203	Gaf domain
S101267_RS14945	COG1017	nitric oxide dioxygenase activity
S101267_RS14945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101267_RS14970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101267_RS14975	COG1378	Sugar-specific transcriptional regulator TrmB
S101267_RS14980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
S101267_RS15000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101267_RS15005	COG0454	-acetyltransferase
S101267_RS15010	COG0517	IMP dehydrogenase activity
S101267_RS15015	COG0123	including yeast histone deacetylase and acetoin utilization protein
S101267_RS15020	COG1360	Flagellar Motor Protein
S101267_RS15025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101267_RS15030	COG1609	Transcriptional regulator
S101267_RS15035	COG1605	Chorismate mutase
S101267_RS15035	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S101267_RS15040	COG3118	belongs to the thioredoxin family
S101267_RS15045	COG4980	gas vesicle protein
S101267_RS15050	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101267_RS15060	COG1674	ftsk spoiiie
S101267_RS15065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101267_RS15075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS15085	COG1363	Peptidase, m42
S101267_RS15090	COG5584	Small secreted protein
S101267_RS15095	COG0281	malic enzyme
S101267_RS15100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101267_RS15115	COG0510	thiamine kinase activity
S101267_RS15120	COG1597	lipid kinase activity
S101267_RS15130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101267_RS15135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101267_RS15140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_RS15145	COG2252	PERMEase
S101267_RS15150	COG4473	ABC transporter
S101267_RS15155	COG1131	(ABC) transporter
S101267_RS15160	COG1349	DNA-binding transcription factor activity
S101267_RS15165	COG1187	pseudouridine synthase activity
S101267_RS15170	COG2244	polysaccharide biosynthetic process
S101267_RS15175	COG2081	HI0933 family
S101267_RS15180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
S101267_RS15190	COG1609	Transcriptional regulator
S101267_RS15195	COG1653	transport
S101267_RS15200	COG1175	transmembrane transport
S101267_RS15205	COG0395	ABC-type sugar transport system, permease component
S101267_RS15210	COG1486	melibiose metabolic process
S101267_RS15220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101267_RS15235	COG1366	Belongs to the anti-sigma-factor antagonist family
S101267_RS15235	COG2202	Pas domain
S101267_RS15240	COG2814	Major facilitator Superfamily
S101267_RS15250	COG0577	efflux transmembrane transporter activity
S101267_RS15255	COG1136	(ABC) transporter
S101267_RS15260	COG2205	protein histidine kinase activity
S101267_RS15265	COG0745	RESPONSE REGULATOR receiver
S101267_RS15270	COG0577	efflux transmembrane transporter activity
S101267_RS15275	COG1136	(ABC) transporter
S101267_RS15295	COG1131	(ABC) transporter
S101267_RS15300	COG1725	Transcriptional regulator
S101267_RS15310	COG1242	4 iron, 4 sulfur cluster binding
S101267_RS15315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S101267_RS15330	COG2267	carboxylic ester hydrolase activity
S101267_RS15335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S101267_RS15340	COG1113	amino acid transport
S101267_RS15345	COG0367	asparagine synthase
S101267_RS15365	COG1506	peptidase
S101267_RS15370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101267_RS15375	COG1116	anion transmembrane transporter activity
S101267_RS15380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101267_RS15385	COG0494	nUDIX hydrolase
S101267_RS15390	COG4824	toxin secretion phage lysis holin
S101267_RS15395	COG0783	Belongs to the Dps family
S101267_RS15420	COG0288	reversible hydration of carbon dioxide
S101267_RS15430	COG1271	oxidase subunit
S101267_RS15435	COG1294	oxidase, subunit
S101267_RS15445	COG4948	Mandelate Racemase Muconate Lactonizing
S101267_RS15455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S101267_RS15460	COG0596	Alpha beta hydrolase
S101267_RS15470	COG1169	isochorismate synthase
S101267_RS15475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101267_RS15480	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S101267_RS15605	COG3859	Proton-coupled thiamine transporter YuaJ
S101267_RS15610	COG2268	Band 7 protein
S101267_RS15615	COG1585	Membrane protein implicated in regulation of membrane protease activity
S101267_RS15620	COG2318	DinB family
S101267_RS15630	COG1454	alcohol dehydrogenase
S101267_RS15635	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS15640	COG1510	regulation of RNA biosynthetic process
S101267_RS15650	COG0569	domain protein
S101267_RS15655	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101267_RS15660	COG1017	nitric oxide dioxygenase activity
S101267_RS15660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101267_RS15675	COG0457	Tetratricopeptide repeat
S101267_RS15710	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS15710	COG1388	LysM domain
S101267_RS15710	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101267_RS15735	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS15750	COG3953	SLT domain
S101267_RS15750	COG5280	Phage tail tape measure protein TP901
S101267_RS15795	COG0740	serine-type endopeptidase activity
S101267_RS15850	COG1216	Glycosyl transferase, family 2
S101267_RS15860	COG4195	phage-related replication protein
S101267_RS15865	COG3420	alginic acid biosynthetic process
S101267_RS15865	COG5434	Belongs to the glycosyl hydrolase 28 family
S101267_RS15940	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
S101267_RS15950	COG0756	dUTP diphosphatase activity
S101267_RS15955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_RS15960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_RS15970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101267_RS15975	COG1780	Probably involved in ribonucleotide reductase function
S101267_RS15995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
S101267_RS16015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS16015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101267_RS16050	COG3655	Transcriptional regulator
S101267_RS16075	COG1484	DNA-dependent DNA replication
S101267_RS16110	COG4974	Belongs to the 'phage' integrase family
S101267_RS16125	COG0628	permease
S101267_RS16130	COG0673	inositol 2-dehydrogenase activity
S101267_RS16135	COG0693	protein deglycase activity
S101267_RS16140	COG0840	transmembrane signaling receptor activity
S101267_RS16145	COG0840	transmembrane signaling receptor activity
S101267_RS16150	COG0840	transmembrane signaling receptor activity
S101267_RS16155	COG0840	transmembrane signaling receptor activity
S101267_RS16170	COG2070	2-Nitropropane dioxygenase
S101267_RS16175	COG0366	Alpha amylase catalytic
S101267_RS16180	COG1253	flavin adenine dinucleotide binding
S101267_RS16185	COG2738	Putative neutral zinc metallopeptidase
S101267_RS16200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S101267_RS16220	COG1979	alcohol dehydrogenase
S101267_RS16225	COG1979	alcohol dehydrogenase
S101267_RS16230	COG2155	Conserved Protein
S101267_RS16235	COG1098	S1 RNA binding domain
S101267_RS16240	COG0436	Aminotransferase
S101267_RS16245	COG1522	sequence-specific DNA binding
S101267_RS16250	COG2267	carboxylic ester hydrolase activity
S101267_RS16260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S101267_RS16265	COG2205	protein histidine kinase activity
S101267_RS16275	COG5018	Exonuclease
S101267_RS16280	COG2814	Major facilitator Superfamily
S101267_RS16285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_RS16290	COG3011	Protein conserved in bacteria
S101267_RS16300	COG3290	protein histidine kinase activity
S101267_RS16305	COG4565	transcriptional regulatory protein
S101267_RS16310	COG1744	ABC transporter substrate-binding protein PnrA-like
S101267_RS16315	COG3845	ABC transporter
S101267_RS16320	COG4603	Belongs to the binding-protein-dependent transport system permease family
S101267_RS16325	COG1079	Belongs to the binding-protein-dependent transport system permease family
S101267_RS16335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101267_RS16335	COG2111	Na H antiporter
S101267_RS16340	COG2111	Na H antiporter
S101267_RS16345	COG1006	Multisubunit Na H antiporter MnhC subunit
S101267_RS16350	COG0651	ATP synthesis coupled electron transport
S101267_RS16355	COG1863	multisubunit Na H antiporter MnhE subunit
S101267_RS16360	COG2212	antiporter activity
S101267_RS16365	COG1320	monovalent cation:proton antiporter activity
S101267_RS16370	COG2050	protein possibly involved in aromatic compounds catabolism
S101267_RS16375	COG2197	response regulator
S101267_RS16380	COG4585	Histidine kinase
S101267_RS16390	COG0142	geranyltranstransferase activity
S101267_RS16410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101267_RS16415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S101267_RS16420	COG1335	isochorismatase
S101267_RS16425	COG5506	Protein of unknown function (DUF1694)
S101267_RS16440	COG0628	permease
S101267_RS16450	COG1418	mRNA catabolic process
S101267_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS16465	COG1511	domain protein
S101267_RS16470	COG0433	COG0433 Predicted ATPase
S101267_RS16470	COG1674	ftsk spoiiie
S101267_RS16475	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101267_RS16480	COG5417	Belongs to the EsaB family
S101267_RS16485	COG4842	Belongs to the WXG100 family
S101267_RS16490	COG2508	Transcriptional regulator
S101267_RS16490	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101267_RS16495	COG0686	Belongs to the AlaDH PNT family
S101267_RS16500	COG5634	Uncharacterized conserved protein (DUF2278)
S101267_RS16505	COG3251	PFAM MbtH domain protein
S101267_RS16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101267_RS16515	COG3433	isochorismatase activity
S101267_RS16515	COG1535	isochorismatase
S101267_RS16520	COG1021	2,3-dihydroxybenzoate-AMP ligase
S101267_RS16525	COG1169	isochorismate synthase
S101267_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS16535	COG2819	hydrolase of the alpha beta superfamily
S101267_RS16540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101267_RS16545	COG1268	BioY protein
S101267_RS16550	COG2056	Na+-H+ antiporter family
S101267_RS16560	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
S101267_RS16565	COG3584	3D domain protein
S101267_RS16575	COG1252	NADH dehydrogenase
S101267_RS16605	COG1131	(ABC) transporter
S101267_RS16630	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101267_RS16635	COG0316	Belongs to the HesB IscA family
S101267_RS16645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_RS16655	COG1252	NADH dehydrogenase
S101267_RS16660	COG4837	Protein of unknown function (DUF1462)
S101267_RS16665	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
S101267_RS16680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S101267_RS16685	COG0460	homoserine dehydrogenase
S101267_RS16690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101267_RS16695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101267_RS16700	COG0647	UMP catabolic process
S101267_RS16705	COG2445	Protein of unknown function DUF86
S101267_RS16710	COG4470	Protein conserved in bacteria
S101267_RS16725	COG0739	heme binding
S101267_RS16735	COG0737	Belongs to the 5'-nucleotidase family
S101267_RS16740	COG0730	response to heat
S101267_RS16745	COG1801	Protein of unknown function DUF72
S101267_RS16760	COG2508	Transcriptional regulator
S101267_RS16770	COG3195	allantoin biosynthetic process
S101267_RS16770	COG3648	Uricase
S101267_RS16780	COG2814	Major facilitator Superfamily
S101267_RS16785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
S101267_RS16790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101267_RS16795	COG2356	endonuclease I
S101267_RS16800	COG3842	ATPase activity
S101267_RS16805	COG2188	Transcriptional regulator
S101267_RS16810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_RS16815	COG0395	ABC-type sugar transport system, permease component
S101267_RS16820	COG1175	transmembrane transport
S101267_RS16825	COG1653	transport
S101267_RS16830	COG2222	sugar isomerase
S101267_RS16835	COG0789	Transcriptional regulator
S101267_RS16860	COG0322	excinuclease ABC activity
S101267_RS16865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101267_RS16885	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS16890	COG0719	Fe-S assembly protein
S101267_RS16895	COG0822	iron-sulfur transferase activity
S101267_RS16900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101267_RS16905	COG0719	Fe-S assembly protein
S101267_RS16910	COG0396	ATPase activity
S101267_RS16920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101267_RS16925	COG1464	Belongs to the NlpA lipoprotein family
S101267_RS16930	COG2011	ABC-type metal ion transport system permease component
S101267_RS16935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
S101267_RS16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101267_RS16965	COG1393	Belongs to the ArsC family
S101267_RS16970	COG1960	acyl-CoA dehydrogenase activity
S101267_RS16975	COG0183	Belongs to the thiolase family
S101267_RS16980	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101267_RS16980	COG1024	Enoyl-CoA hydratase
S101267_RS17000	COG5577	PFAM Coat F domain
S101267_RS17005	COG1846	Transcriptional regulator
S101267_RS17010	COG0477	Major facilitator Superfamily
S101267_RS17035	COG1120	ATPase activity
S101267_RS17050	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS17055	COG0783	Belongs to the Dps family
S101267_RS17060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_RS17065	COG0745	RESPONSE REGULATOR receiver
S101267_RS17070	COG2205	protein histidine kinase activity
S101267_RS17070	COG2770	Histidine kinase
S101267_RS17080	COG1309	transcriptional regulator
S101267_RS17085	COG0114	fumarate hydratase activity
S101267_RS17095	COG0697	spore germination
S101267_RS17100	COG0814	amino acid
S101267_RS17110	COG2197	response regulator
S101267_RS17115	COG4585	Histidine kinase
S101267_RS17120	COG4758	membrane
S101267_RS17125	COG3595	metallopeptidase activity
S101267_RS17130	COG1842	Phage shock protein A
S101267_RS17135	COG4758	membrane
S101267_RS17140	COG2814	Major facilitator Superfamily
S101267_RS17145	COG2096	Adenosyltransferase
S101267_RS17150	COG1120	ATPase activity
S101267_RS17155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS17160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS17170	COG3386	PFAM SMP-30 Gluconolaconase
S101267_RS17175	COG2205	protein histidine kinase activity
S101267_RS17180	COG0745	RESPONSE REGULATOR receiver
S101267_RS17190	COG1191	sigma factor activity
S101267_RS17200	COG2140	Oxalate decarboxylase
S101267_RS17210	COG1120	ATPase activity
S101267_RS17215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS17220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS17225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_RS17230	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S101267_RS17235	COG0531	amino acid
S101267_RS17250	COG1988	membrane-bound metal-dependent
S101267_RS17260	COG1910	domain protein
S101267_RS17265	COG0725	ABC transporter, periplasmic molybdate-binding protein
S101267_RS17270	COG4149	molybdate abc transporter
S101267_RS17275	COG2197	response regulator
S101267_RS17285	COG1131	(ABC) transporter
S101267_RS17295	COG0842	Transport permease protein
S101267_RS17300	COG0656	L-ascorbic acid biosynthetic process
S101267_RS17325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101267_RS17335	COG2860	membrane
S101267_RS17345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S101267_RS17350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S101267_RS17355	COG2217	Heavy metal translocating P-type atpase
S101267_RS17360	COG2217	Heavy metal translocating P-type atpase
S101267_RS17365	COG2608	mercury ion transmembrane transporter activity
S101267_RS17370	COG1937	Protein conserved in bacteria
S101267_RS17375	COG0673	inositol 2-dehydrogenase activity
S101267_RS17385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS17390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
S101267_RS17395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS17400	COG1126	abc transporter atp-binding protein
S101267_RS17405	COG0765	amino acid transport
S101267_RS17410	COG0765	amino acid transport
S101267_RS17415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS17420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101267_RS17425	COG0454	-acetyltransferase
S101267_RS17430	COG0583	DNA-binding transcription factor activity
S101267_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS17440	COG2732	(Barnase) inhibitor
S101267_RS17455	COG0557	exoribonuclease II activity
S101267_RS17460	COG1647	Serine aminopeptidase, S33
S101267_RS17465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101267_RS17470	COG1476	TRANSCRIPTIONal
S101267_RS17475	COG1396	sequence-specific DNA binding
S101267_RS17480	COG1396	sequence-specific DNA binding
S101267_RS17485	COG1733	regulation of RNA biosynthetic process
S101267_RS17510	COG1131	(ABC) transporter
S101267_RS17515	COG1174	glycine betaine transport
S101267_RS17520	COG1732	Glycine betaine
S101267_RS17525	COG1174	glycine betaine transport
S101267_RS17530	COG1125	glycine betaine transport
S101267_RS17530	COG0517	IMP dehydrogenase activity
S101267_RS17535	COG1510	regulation of RNA biosynthetic process
S101267_RS17540	COG1174	glycine betaine transport
S101267_RS17545	COG1732	Glycine betaine
S101267_RS17550	COG1174	glycine betaine transport
S101267_RS17555	COG1125	glycine betaine transport
S101267_RS17555	COG0517	IMP dehydrogenase activity
S101267_RS17560	COG1510	regulation of RNA biosynthetic process
S101267_RS17565	COG2095	MarC family integral membrane protein
S101267_RS17570	COG3064	Membrane
S101267_RS17575	COG4640	response to antibiotic
S101267_RS17580	COG0456	acetyltransferase
S101267_RS17595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101267_RS17615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101267_RS17620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_RS17630	COG2234	aminopeptidase activity
S101267_RS17650	COG0126	phosphoglycerate kinase activity
S101267_RS17660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101267_RS17665	COG2390	Transcriptional regulator
S101267_RS17675	COG1609	Transcriptional regulator
S101267_RS17680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS17690	COG0697	spore germination
S101267_RS17695	COG1113	amino acid transport
S101267_RS17700	COG1737	Transcriptional regulator
S101267_RS17705	COG1070	Carbohydrate kinase
S101267_RS17730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101267_RS17735	COG2186	Transcriptional regulator
S101267_RS17740	COG1620	l-lactate permease
S101267_RS17745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101267_RS17755	COG5039	Polysaccharide pyruvyl transferase
S101267_RS17760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_RS17765	COG0110	maltose O-acetyltransferase activity
S101267_RS17770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S101267_RS17775	COG2244	polysaccharide biosynthetic process
S101267_RS17780	COG1216	Glycosyl transferase, family 2
S101267_RS17785	COG5039	Polysaccharide pyruvyl transferase
S101267_RS17790	COG1216	Glycosyl transferase, family 2
S101267_RS17800	COG0438	transferase activity, transferring glycosyl groups
S101267_RS17805	COG1215	transferase activity, transferring glycosyl groups
S101267_RS17810	COG0438	transferase activity, transferring glycosyl groups
S101267_RS17815	COG1086	Polysaccharide biosynthesis protein
S101267_RS17820	COG0489	protein tyrosine kinase activity
S101267_RS17825	COG3944	biosynthesis protein
S101267_RS17830	COG1396	sequence-specific DNA binding
S101267_RS17835	COG2272	Belongs to the type-B carboxylesterase lipase family
S101267_RS17845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101267_RS17860	COG2364	Membrane
S101267_RS17865	COG0456	acetyltransferase
S101267_RS17870	COG3479	Phenolic acid decarboxylase
S101267_RS17920	COG2223	nitrite transmembrane transporter activity
S101267_RS17925	COG1609	Transcriptional regulator
S101267_RS17935	COG0583	DNA-binding transcription factor activity
S101267_RS17940	COG2828	Protein conserved in bacteria
S101267_RS17945	COG0477	Major facilitator Superfamily
S101267_RS17945	COG2814	Major facilitator Superfamily
S101267_RS17955	COG1611	Belongs to the LOG family
S101267_RS17960	COG1694	Mazg nucleotide pyrophosphohydrolase
S101267_RS17965	COG0659	secondary active sulfate transmembrane transporter activity
S101267_RS17970	COG0288	reversible hydration of carbon dioxide
S101267_RS17980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101267_RS17985	COG4290	ribonuclease
S101267_RS17990	COG2162	N-hydroxyarylamine O-acetyltransferase activity
S101267_RS17995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS18005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S101267_RS18015	COG1051	belongs to the nudix hydrolase family
S101267_RS18020	COG0492	ferredoxin-NADP+ reductase activity
S101267_RS18025	COG3883	PFAM NLP P60 protein
S101267_RS18025	COG0791	NLP P60 protein
S101267_RS18030	COG0457	Tetratricopeptide repeat
S101267_RS18035	COG5002	protein histidine kinase activity
S101267_RS18040	COG0745	RESPONSE REGULATOR receiver
S101267_RS18045	COG1132	(ABC) transporter
S101267_RS18050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S101267_RS18050	COG0140	phosphoribosyl-ATP diphosphatase activity
S101267_RS18075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S101267_RS18090	COG4990	cell redox homeostasis
S101267_RS18095	COG0110	maltose O-acetyltransferase activity
S101267_RS18115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S101267_RS18125	COG2188	Transcriptional regulator
S101267_RS18130	COG1309	transcriptional regulator
S101267_RS18135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S101267_RS18140	COG1950	PFAM Membrane protein of
S101267_RS18145	COG1983	PspC domain protein
S101267_RS18150	COG3595	metallopeptidase activity
S101267_RS18165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S101267_RS18175	COG4897	Protein conserved in bacteria
S101267_RS18185	COG1309	transcriptional regulator
S101267_RS18190	COG2814	Major facilitator Superfamily
S101267_RS18205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_RS18215	COG0793	Belongs to the peptidase S41A family
S101267_RS18215	COG3409	Peptidoglycan-binding domain 1 protein
S101267_RS18220	COG3420	alginic acid biosynthetic process
S101267_RS18225	COG2177	Part of the ABC transporter FtsEX involved in
S101267_RS18230	COG2884	Cell division ATP-binding protein ftsE
S101267_RS18235	COG2010	Cytochrome c
S101267_RS18240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS18255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S101267_RS18270	COG1516	flagellar protein fliS
S101267_RS18275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S101267_RS18280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101267_RS18300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101267_RS18305	COG1256	bacterial-type flagellum assembly
S101267_RS18305	COG4786	Flagellar basal body rod
S101267_RS18310	COG3418	PFAM FlgN family protein
S101267_RS18315	COG2747	anti-sigma28 factor FlgM
S101267_RS18325	COG1040	competence protein
S101267_RS18335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S101267_RS18340	COG1307	EDD domain protein, DegV family
S101267_RS18345	COG2197	response regulator
S101267_RS18350	COG4585	Histidine kinase
S101267_RS18355	COG1739	Uncharacterized protein family UPF0029
S101267_RS18360	COG1316	TRANSCRIPTIONal
S101267_RS18365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101267_RS18370	COG0438	transferase activity, transferring glycosyl groups
S101267_RS18375	COG1215	transferase activity, transferring glycosyl groups
S101267_RS18380	COG3206	protein involved in exopolysaccharide biosynthesis
S101267_RS18385	COG3307	-O-antigen
S101267_RS18390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101267_RS18395	COG0438	transferase activity, transferring glycosyl groups
S101267_RS18395	COG0297	glycogen (starch) synthase activity
S101267_RS18400	COG2244	polysaccharide biosynthetic process
S101267_RS18410	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101267_RS18410	COG2247	cell wall binding repeat
S101267_RS18415	COG2247	cell wall binding repeat
S101267_RS18415	COG2385	sporulation resulting in formation of a cellular spore
S101267_RS18425	COG1316	TRANSCRIPTIONal
S101267_RS18430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S101267_RS18435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101267_RS18440	COG1134	teichoic acid transport
S101267_RS18445	COG1682	transport, permease protein
S101267_RS18450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_RS18455	COG0438	transferase activity, transferring glycosyl groups
S101267_RS18460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S101267_RS18465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S101267_RS18470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_RS18475	COG4193	domain, Protein
S101267_RS18480	COG1482	cell wall glycoprotein biosynthetic process
S101267_RS18485	COG0697	spore germination
S101267_RS18490	COG0814	amino acid
S101267_RS18505	COG1215	transferase activity, transferring glycosyl groups
S101267_RS18510	COG2814	Major facilitator Superfamily
S101267_RS18515	COG1316	TRANSCRIPTIONal
S101267_RS18520	COG0561	phosphatase activity
S101267_RS18525	COG2433	Pfam Transposase IS66
S101267_RS18530	COG0791	NLP P60 protein
S101267_RS18545	COG2843	Capsule synthesis protein
S101267_RS18555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101267_RS18565	COG0697	spore germination
S101267_RS18570	COG0814	amino acid
S101267_RS18580	COG1609	Transcriptional regulator
S101267_RS18585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101267_RS18595	COG1129	ABC transporter
S101267_RS18600	COG1172	Belongs to the binding-protein-dependent transport system permease family
S101267_RS18605	COG1879	ABC-type sugar transport system periplasmic component
S101267_RS18610	COG3103	Sh3 type 3 domain protein
S101267_RS18615	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101267_RS18620	COG3527	Alpha-acetolactate decarboxylase
S101267_RS18625	COG0028	Belongs to the TPP enzyme family
S101267_RS18630	COG0583	DNA-binding transcription factor activity
S101267_RS18635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101267_RS18650	COG5337	Spore coat protein CotH
S101267_RS18660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101267_RS18670	COG0405	Gamma-glutamyltransferase
S101267_RS18675	COG1522	sequence-specific DNA binding
S101267_RS18680	COG2059	Chromate
S101267_RS18685	COG2059	Chromate
S101267_RS18715	COG5444	nuclease activity
S101267_RS18730	COG3878	Protein conserved in bacteria
S101267_RS18735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101267_RS18740	COG4464	protein tyrosine phosphatase activity
S101267_RS18745	COG0489	protein tyrosine kinase activity
S101267_RS18750	COG3944	biosynthesis protein
S101267_RS18765	COG4715	Zinc finger, swim domain protein
S101267_RS18770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101267_RS18775	COG0561	phosphatase activity
S101267_RS18780	COG1349	DNA-binding transcription factor activity
S101267_RS18785	COG0629	single-stranded DNA binding
S101267_RS18810	COG0457	Tetratricopeptide repeat
S101267_RS18815	COG4786	Flagellar basal body rod
S101267_RS18820	COG4786	Flagellar basal body rod
S101267_RS18825	COG1077	Cell shape determining protein MreB Mrl
S101267_RS18830	COG1609	Transcriptional regulator
S101267_RS18835	COG1846	Transcriptional regulator
S101267_RS18840	COG2814	Major facilitator Superfamily
S101267_RS18845	COG1953	Uracil, thiamine, allantoin
S101267_RS18850	COG0477	Major facilitator Superfamily
S101267_RS18855	COG1335	isochorismatase
S101267_RS18860	COG0004	ammonium transporteR
S101267_RS18865	COG0347	Belongs to the P(II) protein family
S101267_RS18870	COG0772	Belongs to the SEDS family
S101267_RS18875	COG0671	phosphoesterase, PA-phosphatase related
S101267_RS18885	COG0739	heme binding
S101267_RS18890	COG1247	-acetyltransferase
S101267_RS18905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS18920	COG2910	NAD(P)H-binding
S101267_RS18925	COG1959	2 iron, 2 sulfur cluster binding
S101267_RS18940	COG0831	urea catabolic process
S101267_RS18945	COG3237	CsbD-like
S101267_RS18950	COG1994	Peptidase M50
S101267_RS18955	COG0457	Tetratricopeptide repeat
S101267_RS18965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S101267_RS18975	COG2304	oxidoreductase activity
S101267_RS18980	COG2304	oxidoreductase activity
S101267_RS18985	COG2385	sporulation resulting in formation of a cellular spore
S101267_RS18990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101267_RS19000	COG4836	Membrane
S101267_RS19070	COG0698	ribose 5-phosphate isomerase
S101267_RS19075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101267_RS19085	COG0009	L-threonylcarbamoyladenylate synthase
S101267_RS19090	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S101267_RS19110	COG2890	protein-(glutamine-N5) methyltransferase activity
S101267_RS19115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S101267_RS19120	COG0346	lactoylglutathione lyase activity
S101267_RS19125	COG0789	Transcriptional regulator
S101267_RS19130	COG0679	Auxin Efflux Carrier
S101267_RS19135	COG0281	malic enzyme
S101267_RS19150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S101267_RS19155	COG1494	fructose-1,6-bisphosphatase
S101267_RS19160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101267_RS19170	COG0191	fructose-bisphosphate aldolase activity
S101267_RS19175	COG2204	response regulator
S101267_RS19180	COG4821	SIS domain
S101267_RS19195	COG2181	nitrate reductase activity
S101267_RS19195	COG0247	lactate metabolic process
S101267_RS19200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS19215	COG1132	(ABC) transporter
S101267_RS19220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS19225	COG2181	nitrate reductase activity
S101267_RS19230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S101267_RS19235	COG1140	nitrate reductase beta subunit
S101267_RS19240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
S101267_RS19245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_RS19255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101267_RS19260	COG2223	nitrite transmembrane transporter activity
S101267_RS19270	COG4506	Protein conserved in bacteria
S101267_RS19280	COG3391	amine dehydrogenase activity
S101267_RS19290	COG0457	Tetratricopeptide repeat
S101267_RS19300	COG0010	Belongs to the arginase family
S101267_RS19305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S101267_RS19310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101267_RS19325	COG1994	Peptidase M50
S101267_RS19330	COG1942	4-Oxalocrotonate Tautomerase
S101267_RS19335	COG1846	Transcriptional regulator
S101267_RS19345	COG0531	amino acid
S101267_RS19350	COG3465	dGTPase activity
S101267_RS19355	COG1078	dGTPase activity
S101267_RS19370	COG1695	Transcriptional regulator
S101267_RS19380	COG1131	(ABC) transporter
S101267_RS19385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101267_RS19415	COG0583	DNA-binding transcription factor activity
S101267_RS19420	COG2855	membrane
S101267_RS19425	COG0280	phosphate acetyltransferase
S101267_RS19445	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS19450	COG0436	Aminotransferase
S101267_RS19460	COG0151	Belongs to the GarS family
S101267_RS19470	COG1917	Cupin 2, conserved barrel domain protein
S101267_RS19480	COG2814	Major facilitator Superfamily
S101267_RS19485	COG2814	Major facilitator Superfamily
S101267_RS19490	COG0833	amino acid
S101267_RS19495	COG4187	Peptidase family M20/M25/M40
S101267_RS19500	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS19505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101267_RS19515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S101267_RS19520	COG1091	dTDP-4-dehydrorhamnose reductase activity
S101267_RS19525	COG1088	dTDP-glucose 4,6-dehydratase activity
S101267_RS19530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S101267_RS19535	COG3980	spore coat polysaccharide biosynthesis protein
S101267_RS19540	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
S101267_RS19545	COG2089	acid synthase
S101267_RS19550	COG0456	acetyltransferase
S101267_RS19555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101267_RS19560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101267_RS19565	COG0463	Glycosyl transferase, family 2
S101267_RS19575	COG2363	Small membrane protein
S101267_RS19580	COG2233	PERMEase
S101267_RS19595	COG1216	Glycosyl transferase, family 2
S101267_RS19605	COG0351	phosphomethylpyrimidine kinase
S101267_RS19615	COG1621	beta-fructofuranosidase activity
S101267_RS19620	COG1263	PTS System
S101267_RS19620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS19625	COG3711	transcriptional antiterminator
S101267_RS19635	COG1404	Belongs to the peptidase S8 family
S101267_RS19640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101267_RS19645	COG2378	regulation of single-species biofilm formation
S101267_RS19665	COG0778	Nitroreductase
S101267_RS19670	COG0772	Belongs to the SEDS family
S101267_RS19675	COG0454	-acetyltransferase
S101267_RS19695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101267_RS19700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101267_RS19705	COG2261	transglycosylase associated protein
S101267_RS19710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101267_RS19715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101267_RS19720	COG2246	polysaccharide biosynthetic process
S101267_RS19725	COG1309	transcriptional regulator
S101267_RS19735	COG2813	Specifically methylates the guanine in position
S101267_RS19735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
S101267_RS19745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101267_RS19750	COG2837	iron assimilation
S101267_RS19755	COG2822	iron ion transport
S101267_RS19760	COG0672	)-iron permease
S101267_RS19775	COG0583	DNA-binding transcription factor activity
S101267_RS19785	COG1346	cytolysis
S101267_RS19790	COG4895	conserved protein (DUF2196)
S101267_RS19795	COG0789	Transcriptional regulator
S101267_RS19800	COG5504	Zn-dependent protease
S101267_RS19805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
S101267_RS19810	COG0346	lactoylglutathione lyase activity
S101267_RS19815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS19820	COG1404	Belongs to the peptidase S8 family
S101267_RS19825	COG1442	glycosyl transferase family 8
S101267_RS19830	COG2357	RelA SpoT domain protein
S101267_RS19835	COG1575	Belongs to the MenA family. Type 1 subfamily
S101267_RS19855	COG1696	Membrane protein involved in D-alanine export
S101267_RS19865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
S101267_RS19870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101267_RS19875	COG1486	melibiose metabolic process
S101267_RS19880	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_RS19885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS19890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS19895	COG3711	transcriptional antiterminator
S101267_RS19895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101267_RS19910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS19915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101267_RS19925	COG0640	Transcriptional regulator
S101267_RS19930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101267_RS19935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS19940	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101267_RS19945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101267_RS19950	COG2723	6-phospho-beta-galactosidase activity
S101267_RS19955	COG1940	carbohydrate kinase activity
S101267_RS19960	COG1482	cell wall glycoprotein biosynthetic process
S101267_RS19970	COG0753	catalase activity
S101267_RS19975	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S101267_RS19980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101267_RS19990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S101267_RS19995	COG4988	ABC transporter
S101267_RS20000	COG1294	oxidase, subunit
S101267_RS20005	COG1271	oxidase subunit
S101267_RS20010	COG3493	citrate carrier protein
S101267_RS20015	COG0726	polysaccharide deacetylase
S101267_RS20020	COG3842	ATPase activity
S101267_RS20025	COG2508	Transcriptional regulator
S101267_RS20030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS20040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101267_RS20050	COG4894	glucomannan catabolic process
S101267_RS20055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101267_RS20060	COG0500	methyltransferase
S101267_RS20065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_RS20085	COG0693	protein deglycase activity
S101267_RS20085	COG0753	catalase activity
S101267_RS20090	COG2851	Citrate transporter
S101267_RS20095	COG2273	Hydrolase Family 16
S101267_RS20100	COG3711	transcriptional antiterminator
S101267_RS20105	COG2270	Major facilitator Superfamily
S101267_RS20110	COG0513	Belongs to the DEAD box helicase family
S101267_RS20155	COG0697	spore germination
S101267_RS20160	COG0589	response to stress
S101267_RS20165	COG2723	6-phospho-beta-galactosidase activity
S101267_RS20170	COG2190	(PTS) system
S101267_RS20170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101267_RS20170	COG1263	PTS System
S101267_RS20185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
S101267_RS20205	COG3507	Belongs to the glycosyl hydrolase 43 family
S101267_RS20230	COG0010	Belongs to the arginase family
S101267_RS20235	COG0833	amino acid
S101267_RS20240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S101267_RS20245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101267_RS20255	COG2390	Transcriptional regulator
S101267_RS20260	COG0561	phosphatase activity
S101267_RS20290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101267_RS20295	COG5294	Protein conserved in bacteria
S101267_RS20300	COG0577	efflux transmembrane transporter activity
S101267_RS20305	COG1136	(ABC) transporter
S101267_RS20310	COG2205	protein histidine kinase activity
S101267_RS20315	COG0745	RESPONSE REGULATOR receiver
S101267_RS20330	COG1082	Xylose isomerase domain protein TIM barrel
S101267_RS20340	COG2814	Major facilitator Superfamily
S101267_RS20370	COG1349	DNA-binding transcription factor activity
S101267_RS20375	COG0667	Aldo Keto reductase
S101267_RS20380	COG2814	Major facilitator Superfamily
S101267_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
S101267_RS20395	COG2197	response regulator
S101267_RS20400	COG4585	Histidine kinase
S101267_RS20405	COG3239	Fatty acid desaturase
S101267_RS20410	COG1309	transcriptional regulator
S101267_RS20415	COG1012	belongs to the aldehyde dehydrogenase family
S101267_RS20420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
S101267_RS20430	COG0640	Transcriptional regulator
S101267_RS20435	COG2814	Major facilitator Superfamily
S101267_RS20440	COG1714	RDD family
S101267_RS20450	COG0450	alkyl hydroperoxide reductase
S101267_RS20455	COG3634	alkyl hydroperoxide reductase activity
S101267_RS20465	COG1113	amino acid transport
S101267_RS20520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101267_RS20535	COG2323	membrane
S101267_RS20545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101267_RS20550	COG2323	membrane
S101267_RS20560	COG2080	2 iron, 2 sulfur cluster binding
S101267_RS20570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
S101267_RS20575	COG2068	MobA-Related Protein
S101267_RS20580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
S101267_RS20630	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S101267_RS20635	COG0667	Aldo Keto reductase
S101267_RS20640	COG0456	acetyltransferase
S101267_RS20645	COG0457	Tetratricopeptide repeat
S101267_RS20650	COG0010	Belongs to the arginase family
S101267_RS20655	COG0833	amino acid
S101267_RS20660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101267_RS20665	COG5658	integral membrane protein
S101267_RS20670	COG0640	Transcriptional regulator
S101267_RS20675	COG3829	transcription factor binding
S101267_RS20690	COG5002	protein histidine kinase activity
S101267_RS20690	COG3850	Histidine kinase
S101267_RS20695	COG0745	RESPONSE REGULATOR receiver
S101267_RS20705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101267_RS20710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S101267_RS20715	COG4853	Protein conserved in bacteria
S101267_RS20720	COG4863	YycH protein
S101267_RS20725	COG5002	protein histidine kinase activity
S101267_RS20730	COG0745	RESPONSE REGULATOR receiver
S101267_RS20765	COG0346	lactoylglutathione lyase activity
S101267_RS20770	COG0305	Participates in initiation and elongation during chromosome replication
S101267_RS20785	COG3093	addiction module antidote protein HigA
S101267_RS20800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
S101267_RS20825	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S101267_RS20830	COG4241	membrane
S101267_RS20840	COG5577	PFAM Coat F domain
S101267_RS20845	COG1733	regulation of RNA biosynthetic process
S101267_RS20855	COG0697	spore germination
S101267_RS20860	COG1621	beta-fructofuranosidase activity
S101267_RS20865	COG1621	beta-fructofuranosidase activity
S101267_RS20875	COG2318	DinB family
S101267_RS20880	COG2211	Major facilitator Superfamily
S101267_RS20895	COG0778	Nitroreductase
S101267_RS20900	COG1846	Transcriptional regulator
S101267_RS20905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101267_RS20910	COG1846	Transcriptional regulator
S101267_RS20915	COG2153	protein acetylation
S101267_RS20920	COG0640	Transcriptional regulator
S101267_RS20935	COG0457	Tetratricopeptide repeat
S101267_RS20960	COG0741	lytic transglycosylase activity
S101267_RS20960	COG0791	NLP P60 protein
S101267_RS20965	COG5644	endopeptidase inhibitor activity
S101267_RS20975	COG0433	COG0433 Predicted ATPase
S101267_RS21025	COG2946	Replication initiation factor
S101267_RS21030	COG1674	ftsk spoiiie
S101267_RS21035	COG1674	ftsk spoiiie
S101267_RS21060	COG1396	sequence-specific DNA binding
S101267_RS21065	COG2856	Zn peptidase
S101267_RS21070	COG0457	Tetratricopeptide repeat
S101267_RS21075	COG1331	Highly conserved protein containing a thioredoxin domain
S101267_RS21085	COG1266	CAAX protease self-immunity
S101267_RS21090	COG2814	Major facilitator Superfamily
S101267_RS21090	COG0477	Major facilitator Superfamily
S101267_RS21095	COG0346	lactoylglutathione lyase activity
S101267_RS21105	COG0708	Exodeoxyribonuclease III
S101267_RS21110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101267_RS21115	COG2169	Transcriptional regulator
S101267_RS21125	COG0629	single-stranded DNA binding
S101267_RS21135	COG0012	GTP binding
S101267_RS21140	COG0243	molybdopterin cofactor binding
S101267_RS21145	COG4481	Protein conserved in bacteria
S101267_RS21150	COG3949	Membrane
S101267_RS21165	COG1475	DNA binding
S101267_RS21170	COG1192	Involved in chromosome partitioning
S101267_RS21195	COG1847	R3H domain protein
S101267_RS21200	COG0706	membrane insertase activity
S101267_RS21220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S101267_RS21250	COG4641	Protein conserved in bacteria
S101267_RS21260	COG1086	Polysaccharide biosynthesis protein
S101267_RS21280	COG4698	Protein conserved in bacteria
S101267_RS21285	COG2755	lipolytic protein G-D-S-L family
S101267_RS21290	COG1999	signal sequence binding