locus-tag	class	description
OU987_RS00010	COG0592	DNA-directed DNA polymerase activity
OU987_RS00015	COG2501	S4 domain
OU987_RS00030	COG0187	DNA topoisomerase II activity
OU987_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OU987_RS00070	COG0516	GMP reductase activity
OU987_RS00070	COG0517	IMP dehydrogenase activity
OU987_RS00075	COG1686	Belongs to the peptidase S11 family
OU987_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
OU987_RS00105	COG1428	Deoxynucleoside kinase
OU987_RS00110	COG1428	Deoxynucleoside kinase
OU987_RS00115	COG1388	LysM domain
OU987_RS00115	COG3858	chitin binding
OU987_RS00120	COG1335	isochorismatase
OU987_RS00125	COG0590	tRNA wobble adenosine to inosine editing
OU987_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OU987_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OU987_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OU987_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OU987_RS00195	COG3853	Toxic anion resistance protein (TelA)
OU987_RS00200	COG1982	Orn Lys Arg decarboxylase major
OU987_RS00210	COG3870	Protein conserved in bacteria
OU987_RS00215	COG1728	Protein conserved in bacteria
OU987_RS00220	COG0470	DNA polymerase III
OU987_RS00225	COG1774	PSP1 C-terminal conserved region
OU987_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OU987_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OU987_RS00250	COG2002	toxin-antitoxin pair type II binding
OU987_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU987_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU987_RS00260	COG0084	hydrolase, TatD family'
OU987_RS00265	COG3584	3D domain protein
OU987_RS00265	COG3583	domain protein
OU987_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OU987_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OU987_RS00285	COG4466	Protein conserved in bacteria
OU987_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OU987_RS00305	COG0251	oxidation-reduction process
OU987_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OU987_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OU987_RS00345	COG2002	toxin-antitoxin pair type II binding
OU987_RS00350	COG2244	polysaccharide biosynthetic process
OU987_RS00355	COG3956	TIGRFAM MazG family protein
OU987_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OU987_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OU987_RS00380	COG1098	S1 RNA binding domain
OU987_RS00395	COG2208	phosphoserine phosphatase activity
OU987_RS00400	COG2304	oxidoreductase activity
OU987_RS00405	COG0515	serine threonine protein kinase
OU987_RS00410	COG0037	tRNA processing
OU987_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OU987_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OU987_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OU987_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU987_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OU987_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
OU987_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU987_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OU987_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OU987_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OU987_RS00475	COG1396	sequence-specific DNA binding
OU987_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OU987_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OU987_RS00565	COG4463	regulation of RNA biosynthetic process
OU987_RS00570	COG3880	PFAM UvrB UvrC protein
OU987_RS00580	COG0542	response to heat
OU987_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OU987_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OU987_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
OU987_RS00615	COG1045	serine acetyltransferase
OU987_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OU987_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OU987_RS00635	COG3688	RNA-binding protein containing a PIN domain
OU987_RS00640	COG1595	DNA-templated transcription, initiation
OU987_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OU987_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
OU987_RS00680	COG2813	Specifically methylates the guanine in position
OU987_RS00695	COG1358	cellular component organization or biogenesis
OU987_RS00720	COG0596	Alpha beta hydrolase
OU987_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OU987_RS00830	COG0201	protein transport
OU987_RS00840	COG0024	Methionine aminopeptidase
OU987_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OU987_RS00880	COG1122	ATPase activity
OU987_RS00885	COG1122	ATPase activity
OU987_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OU987_RS00910	COG2226	methyltransferase
OU987_RS00915	COG2318	DinB family
OU987_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS00930	COG0489	protein tyrosine kinase activity
OU987_RS00940	COG2194	sulfuric ester hydrolase activity
OU987_RS00945	COG0726	polysaccharide deacetylase
OU987_RS01005	COG0738	Major facilitator superfamily
OU987_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OU987_RS01020	COG1063	alcohol dehydrogenase
OU987_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
OU987_RS01030	COG0385	Bile acid
OU987_RS01035	COG2819	hydrolase of the alpha beta superfamily
OU987_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU987_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU987_RS01055	COG2207	Transcriptional regulator
OU987_RS01060	COG3876	Protein conserved in bacteria
OU987_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
OU987_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU987_RS01075	COG1263	PTS System
OU987_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU987_RS01090	COG1683	Conserved Protein
OU987_RS01120	COG1595	DNA-templated transcription, initiation
OU987_RS01125	COG5662	AntiSigma factor
OU987_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OU987_RS01135	COG4856	YbbR-like protein
OU987_RS01170	COG5002	protein histidine kinase activity
OU987_RS01175	COG1136	(ABC) transporter
OU987_RS01180	COG0577	efflux transmembrane transporter activity
OU987_RS01185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OU987_RS01200	COG1346	cytolysis
OU987_RS01205	COG1380	Effector of murein hydrolase LrgA
OU987_RS01210	COG1846	Transcriptional regulator
OU987_RS01215	COG1113	amino acid transport
OU987_RS01220	COG1011	Hydrolase
OU987_RS01225	COG4585	Histidine kinase
OU987_RS01230	COG2197	response regulator
OU987_RS01235	COG1131	(ABC) transporter
OU987_RS01275	COG0531	amino acid
OU987_RS01280	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OU987_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
OU987_RS01300	COG2271	Major facilitator Superfamily
OU987_RS01310	COG2368	4-hydroxyphenylacetate
OU987_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS01335	COG1397	ADP-ribosylglycohydrolase
OU987_RS01340	COG5444	nuclease activity
OU987_RS01350	COG0371	Dehydrogenase
OU987_RS01360	COG1183	phosphatidylcholine synthase activity
OU987_RS01365	COG0586	Pfam SNARE associated Golgi protein
OU987_RS01370	COG0688	phosphatidylethanolamine metabolic process
OU987_RS01385	COG1301	dicarboxylic acid transport
OU987_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU987_RS01395	COG0833	amino acid
OU987_RS01400	COG2040	homocysteine
OU987_RS01405	COG1115	amino acid carrier protein
OU987_RS01410	COG2066	Belongs to the glutaminase family
OU987_RS01415	COG4191	Histidine kinase
OU987_RS01420	COG0784	Response regulator, receiver
OU987_RS01440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OU987_RS01445	COG0778	Nitroreductase
OU987_RS01450	COG0346	lactoylglutathione lyase activity
OU987_RS01455	COG2259	Doxx family
OU987_RS01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS01475	COG3773	Cell wall hydrolase
OU987_RS01480	COG3540	Alkaline phosphatase
OU987_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OU987_RS01490	COG0805	protein transport
OU987_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OU987_RS01505	COG0477	Major facilitator Superfamily
OU987_RS01510	COG1309	transcriptional regulator
OU987_RS01515	COG0252	asparaginase activity
OU987_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OU987_RS01525	COG3012	SEC-C Motif Domain Protein
OU987_RS01525	COG1405	negative regulation of cell septum assembly
OU987_RS01540	COG1595	DNA-templated transcription, initiation
OU987_RS01545	COG1595	DNA-templated transcription, initiation
OU987_RS01550	COG1876	peptidase activity
OU987_RS01555	COG0457	Tetratricopeptide repeat
OU987_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS01565	COG0366	Alpha amylase catalytic
OU987_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
OU987_RS01575	COG1121	(ABC) transporter
OU987_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OU987_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS01590	COG2310	stress, protein
OU987_RS01595	COG2310	stress, protein
OU987_RS01600	COG2310	stress, protein
OU987_RS01605	COG0861	Integral membrane protein TerC family
OU987_RS01615	COG3853	Toxic anion resistance protein (TelA)
OU987_RS01620	COG0477	Major facilitator Superfamily
OU987_RS01625	COG4175	Glycine betaine
OU987_RS01625	COG0517	IMP dehydrogenase activity
OU987_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
OU987_RS01635	COG2113	Glycine betaine
OU987_RS01640	COG1473	amidohydrolase
OU987_RS01645	COG1288	antiporter activity
OU987_RS01665	COG2814	Major facilitator Superfamily
OU987_RS01670	COG1846	Transcriptional regulator
OU987_RS01675	COG1280	lysine exporter protein (LysE YggA)
OU987_RS01680	COG3403	YqcI/YcgG family
OU987_RS01685	COG1113	amino acid transport
OU987_RS01690	COG3665	Urea carboxylase-associated protein
OU987_RS01705	COG1660	Displays ATPase and GTPase activities
OU987_RS01710	COG1082	Xylose isomerase domain protein TIM barrel
OU987_RS01715	COG2271	Major facilitator Superfamily
OU987_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OU987_RS01725	COG3458	cephalosporin-C deacetylase activity
OU987_RS01730	COG3541	Predicted nucleotidyltransferase
OU987_RS01735	COG0506	proline dehydrogenase activity
OU987_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU987_RS01750	COG2508	Transcriptional regulator
OU987_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OU987_RS01760	COG1587	Uroporphyrinogen-III synthase
OU987_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
OU987_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OU987_RS01775	COG0243	molybdopterin cofactor binding
OU987_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OU987_RS01785	COG2223	nitrite transmembrane transporter activity
OU987_RS01790	COG0523	cobalamin synthesis protein
OU987_RS01795	COG1063	alcohol dehydrogenase
OU987_RS01800	COG1714	RDD family
OU987_RS01820	COG3209	COG3209 Rhs family protein
OU987_RS01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OU987_RS01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OU987_RS01835	COG1733	regulation of RNA biosynthetic process
OU987_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS01870	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OU987_RS01885	COG2364	Membrane
OU987_RS01890	COG1126	abc transporter atp-binding protein
OU987_RS01895	COG0765	amino acid transport
OU987_RS01905	COG0583	DNA-binding transcription factor activity
OU987_RS01910	COG0163	prenyltransferase activity
OU987_RS01915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OU987_RS01930	COG3104	oligopeptide transport
OU987_RS01935	COG5434	Belongs to the glycosyl hydrolase 28 family
OU987_RS01945	COG0697	spore germination
OU987_RS01955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OU987_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS01965	COG0456	acetyltransferase
OU987_RS01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU987_RS01975	COG0765	amino acid transport
OU987_RS01980	COG1126	abc transporter atp-binding protein
OU987_RS01985	COG1473	amidohydrolase
OU987_RS01990	COG2079	MmgE PrpD family protein
OU987_RS01995	COG1136	(ABC) transporter
OU987_RS02000	COG0577	efflux transmembrane transporter activity
OU987_RS02005	COG0745	RESPONSE REGULATOR receiver
OU987_RS02010	COG5002	protein histidine kinase activity
OU987_RS02010	COG3850	Histidine kinase
OU987_RS02015	COG0457	Tetratricopeptide repeat
OU987_RS02030	COG0527	aspartate kinase activity
OU987_RS02035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS02040	COG4605	iron ion homeostasis
OU987_RS02045	COG4604	ABC transporter, ATP-binding protein
OU987_RS02050	COG4607	ABC-type enterochelin transport system periplasmic component
OU987_RS02055	COG2814	Major facilitator Superfamily
OU987_RS02060	COG1309	transcriptional regulator
OU987_RS02065	COG0778	Nitroreductase
OU987_RS02070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OU987_RS02075	COG0640	Transcriptional regulator
OU987_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OU987_RS02090	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS02095	COG4975	Glucose uptake
OU987_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS02105	COG4549	nuclear export factor GLE1
OU987_RS02110	COG1276	copper resistance
OU987_RS02110	COG2372	response to copper ion
OU987_RS02115	COG1349	DNA-binding transcription factor activity
OU987_RS02125	COG2213	PTS system mannitol-specific
OU987_RS02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OU987_RS02150	COG0561	phosphatase activity
OU987_RS02160	COG1914	H( )-stimulated, divalent metal cation uptake system
OU987_RS02170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OU987_RS02175	COG1984	allophanate hydrolase subunit 2
OU987_RS02180	COG1414	Transcriptional regulator
OU987_RS02185	COG2755	lipolytic protein G-D-S-L family
OU987_RS02195	COG2329	Antibiotic biosynthesis monooxygenase
OU987_RS02200	COG0768	penicillin binding
OU987_RS02205	COG4989	oxidoreductase activity
OU987_RS02210	COG3711	transcriptional antiterminator
OU987_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS02225	COG1917	Cupin 2, conserved barrel domain protein
OU987_RS02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU987_RS02235	COG3871	stress protein (general stress protein 26)
OU987_RS02245	COG2814	Major facilitator Superfamily
OU987_RS02250	COG1522	sequence-specific DNA binding
OU987_RS02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OU987_RS02255	COG0551	DNA topoisomerase type I activity
OU987_RS02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OU987_RS02265	COG3706	GGDEF domain
OU987_RS02270	COG5298	Protein conserved in bacteria
OU987_RS02275	COG1215	transferase activity, transferring glycosyl groups
OU987_RS02285	COG0531	amino acid
OU987_RS02295	COG0028	Belongs to the TPP enzyme family
OU987_RS02300	COG1388	LysM domain
OU987_RS02300	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS02300	COG5632	N-Acetylmuramoyl-L-alanine amidase
OU987_RS02320	COG0457	Tetratricopeptide repeat
OU987_RS02350	COG1914	H( )-stimulated, divalent metal cation uptake system
OU987_RS02370	COG2076	Multidrug Resistance protein
OU987_RS02375	COG2217	Heavy metal translocating P-type atpase
OU987_RS02380	COG3729	General stress protein
OU987_RS02385	COG0662	Cupin 2, conserved barrel domain protein
OU987_RS02390	COG2329	Antibiotic biosynthesis monooxygenase
OU987_RS02395	COG3546	catalase activity
OU987_RS02400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OU987_RS02405	COG3290	protein histidine kinase activity
OU987_RS02410	COG4565	transcriptional regulatory protein
OU987_RS02415	COG1301	dicarboxylic acid transport
OU987_RS02420	COG0628	permease
OU987_RS02425	COG1131	(ABC) transporter
OU987_RS02430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU987_RS02440	COG1960	acyl-CoA dehydrogenase activity
OU987_RS02455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OU987_RS02460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS02470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OU987_RS02475	COG0513	Belongs to the DEAD box helicase family
OU987_RS02480	COG3402	PFAM membrane-flanked domain
OU987_RS02485	COG3428	Bacterial PH domain
OU987_RS02490	COG0705	Rhomboid family
OU987_RS02500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OU987_RS02505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OU987_RS02510	COG0864	Transcriptional regulator
OU987_RS02515	COG2337	Toxic component of a toxin-antitoxin (TA) module
OU987_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS02530	COG2172	sigma factor antagonist activity
OU987_RS02535	COG2208	phosphoserine phosphatase activity
OU987_RS02540	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS02550	COG1191	sigma factor activity
OU987_RS02555	COG2208	phosphoserine phosphatase activity
OU987_RS02560	COG2183	response to ionizing radiation
OU987_RS02625	COG5444	nuclease activity
OU987_RS02645	COG0477	Major facilitator Superfamily
OU987_RS02660	COG2030	dehydratase
OU987_RS02670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OU987_RS02675	COG1959	2 iron, 2 sulfur cluster binding
OU987_RS02680	COG2910	NAD(P)H-binding
OU987_RS02685	COG3239	Fatty acid desaturase
OU987_RS02690	COG1278	Cold shock
OU987_RS02695	COG1329	Transcriptional regulator
OU987_RS02700	COG1937	Protein conserved in bacteria
OU987_RS02705	COG2210	Belongs to the sulfur carrier protein TusA family
OU987_RS02710	COG1054	Belongs to the UPF0176 family
OU987_RS02715	COG0425	Belongs to the sulfur carrier protein TusA family
OU987_RS02715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU987_RS02725	COG0425	Belongs to the sulfur carrier protein TusA family
OU987_RS02730	COG0730	response to heat
OU987_RS02735	COG1794	racemase activity, acting on amino acids and derivatives
OU987_RS02750	COG3621	Patatin-like phospholipase
OU987_RS02760	COG0662	Cupin 2, conserved barrel domain protein
OU987_RS02775	COG0277	FAD linked oxidase domain protein
OU987_RS02800	COG0662	Cupin 2, conserved barrel domain protein
OU987_RS02805	COG2318	DinB family
OU987_RS02835	COG1064	alcohol dehydrogenase
OU987_RS02840	COG0789	Transcriptional regulator
OU987_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS02860	COG2814	Major facilitator Superfamily
OU987_RS02865	COG1309	transcriptional regulator
OU987_RS02870	COG0697	spore germination
OU987_RS02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS02880	COG5577	PFAM Coat F domain
OU987_RS02890	COG1063	alcohol dehydrogenase
OU987_RS02895	COG5577	PFAM Coat F domain
OU987_RS02905	COG4585	Histidine kinase
OU987_RS02910	COG2197	response regulator
OU987_RS02915	COG2409	Drug exporters of the RND superfamily
OU987_RS02920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OU987_RS02925	COG0488	(ABC) transporter
OU987_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU987_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS02945	COG2814	Major facilitator Superfamily
OU987_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OU987_RS02960	COG0730	response to heat
OU987_RS02965	COG0456	acetyltransferase
OU987_RS02970	COG0789	Transcriptional regulator
OU987_RS02970	COG4978	Transcriptional regulator
OU987_RS02975	COG0697	spore germination
OU987_RS02980	COG1051	belongs to the nudix hydrolase family
OU987_RS02985	COG2226	methyltransferase
OU987_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
OU987_RS02995	COG1802	Transcriptional regulator
OU987_RS03000	COG1819	glycosyl
OU987_RS03015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU987_RS03025	COG1388	LysM domain
OU987_RS03030	COG2814	Major facilitator Superfamily
OU987_RS03035	COG2188	Transcriptional regulator
OU987_RS03040	COG2186	Transcriptional regulator
OU987_RS03045	COG2807	transmembrane transport
OU987_RS03050	COG2076	Multidrug Resistance protein
OU987_RS03055	COG2076	Multidrug Resistance protein
OU987_RS03060	COG1309	transcriptional regulator
OU987_RS03065	COG0531	amino acid
OU987_RS03075	COG3832	glyoxalase III activity
OU987_RS03080	COG0604	alcohol dehydrogenase
OU987_RS03085	COG2814	Major facilitator Superfamily
OU987_RS03125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OU987_RS03130	COG0802	atpase or kinase
OU987_RS03135	COG1214	PFAM Peptidase M22, glycoprotease
OU987_RS03140	COG0456	acetyltransferase
OU987_RS03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OU987_RS03150	COG0488	(ABC) transporter
OU987_RS03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OU987_RS03170	COG0805	protein transport
OU987_RS03180	COG1266	CAAX protease self-immunity
OU987_RS03225	COG0457	Tetratricopeptide repeat
OU987_RS03230	COG1063	alcohol dehydrogenase
OU987_RS03235	COG2211	Major facilitator Superfamily
OU987_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU987_RS03250	COG1842	Phage shock protein A
OU987_RS03255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OU987_RS03260	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OU987_RS03265	COG4260	virion core protein, lumpy skin disease virus
OU987_RS03270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OU987_RS03270	COG2755	lipolytic protein G-D-S-L family
OU987_RS03280	COG1595	DNA-templated transcription, initiation
OU987_RS03285	COG1063	alcohol dehydrogenase
OU987_RS03290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OU987_RS03295	COG0823	Involved in the tonB-independent uptake of proteins
OU987_RS03305	COG2132	Multicopper oxidase
OU987_RS03310	COG1113	amino acid transport
OU987_RS03315	COG0714	Associated with various cellular activities
OU987_RS03320	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OU987_RS03325	COG1305	Transglutaminase-like
OU987_RS03350	COG2252	PERMEase
OU987_RS03355	COG3064	Membrane
OU987_RS03375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OU987_RS03380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OU987_RS03385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OU987_RS03390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OU987_RS03395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OU987_RS03410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OU987_RS03420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OU987_RS03425	COG0138	bifunctional purine biosynthesis protein purh
OU987_RS03430	COG0151	Belongs to the GarS family
OU987_RS03440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OU987_RS03445	COG1470	cell adhesion involved in biofilm formation
OU987_RS03450	COG4496	protein, YerC YecD
OU987_RS03455	COG0069	glutamate synthase activity
OU987_RS03465	COG0210	DNA helicase
OU987_RS03475	COG4851	CamS sex pheromone cAM373 precursor
OU987_RS03480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OU987_RS03485	COG1285	pathogenesis
OU987_RS03490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU987_RS03510	COG1309	transcriptional regulator
OU987_RS03515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OU987_RS03520	COG1597	lipid kinase activity
OU987_RS03525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OU987_RS03535	COG1131	(ABC) transporter
OU987_RS03575	COG5444	nuclease activity
OU987_RS03605	COG3546	catalase activity
OU987_RS03610	COG0454	-acetyltransferase
OU987_RS03620	COG2323	membrane
OU987_RS03625	COG2329	Antibiotic biosynthesis monooxygenase
OU987_RS03630	COG0346	lactoylglutathione lyase activity
OU987_RS03635	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS03640	COG5583	Uncharacterized small protein (DUF2292)
OU987_RS03645	COG0196	riboflavin kinase activity
OU987_RS03650	COG0670	Belongs to the BI1 family
OU987_RS03655	COG1846	Transcriptional regulator
OU987_RS03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OU987_RS03670	COG2124	cytochrome p450
OU987_RS03670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OU987_RS03675	COG1368	sulfuric ester hydrolase activity
OU987_RS03680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OU987_RS03685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS03690	COG1442	glycosyl transferase family 8
OU987_RS03695	COG1216	Glycosyl transferase, family 2
OU987_RS03700	COG1442	glycosyl transferase family 8
OU987_RS03705	COG2223	nitrite transmembrane transporter activity
OU987_RS03710	COG0531	amino acid
OU987_RS03715	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS03720	COG0840	transmembrane signaling receptor activity
OU987_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS03730	COG0463	Glycosyl transferase, family 2
OU987_RS03730	COG0457	Tetratricopeptide repeat
OU987_RS03735	COG0488	(ABC) transporter
OU987_RS03740	COG0789	Transcriptional regulator
OU987_RS03745	COG2814	Major facilitator Superfamily
OU987_RS03750	COG0488	(ABC) transporter
OU987_RS03755	COG0513	Belongs to the DEAD box helicase family
OU987_RS03760	COG0456	acetyltransferase
OU987_RS03765	COG2130	NADP-dependent
OU987_RS03780	COG3866	Pectate lyase
OU987_RS03785	COG0471	metal ion transport
OU987_RS03815	COG3290	protein histidine kinase activity
OU987_RS03820	COG4565	transcriptional regulatory protein
OU987_RS03825	COG3181	Tripartite tricarboxylate transporter family receptor
OU987_RS03830	COG2851	Citrate transporter
OU987_RS03835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS03840	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OU987_RS03850	COG2258	MOSC domain
OU987_RS03870	COG0024	Methionine aminopeptidase
OU987_RS03875	COG1263	PTS System
OU987_RS03875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS03885	COG1368	sulfuric ester hydrolase activity
OU987_RS03895	COG0071	Belongs to the small heat shock protein (HSP20) family
OU987_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS03910	COG1263	PTS System
OU987_RS03915	COG0366	Alpha amylase catalytic
OU987_RS03920	COG2188	Transcriptional regulator
OU987_RS03925	COG0778	Nitroreductase
OU987_RS03940	COG0737	Belongs to the 5'-nucleotidase family
OU987_RS03945	COG0693	protein deglycase activity
OU987_RS03950	COG1609	Transcriptional regulator
OU987_RS03965	COG2814	Major facilitator Superfamily
OU987_RS03975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OU987_RS03980	COG4980	gas vesicle protein
OU987_RS03985	COG1295	ribonuclease BN
OU987_RS03990	COG0477	Major facilitator Superfamily
OU987_RS03995	COG0387	Pfam Sodium calcium exchanger
OU987_RS04005	COG0668	transmembrane transport
OU987_RS04010	COG0535	radical SAM domain protein
OU987_RS04020	COG0726	polysaccharide deacetylase
OU987_RS04040	COG0745	RESPONSE REGULATOR receiver
OU987_RS04045	COG2205	protein histidine kinase activity
OU987_RS04050	COG2084	Dehydrogenase
OU987_RS04060	COG0598	Magnesium transport protein CorA
OU987_RS04065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OU987_RS04070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OU987_RS04085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OU987_RS04090	COG4637	Psort location Cytoplasmic, score
OU987_RS04095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU987_RS04100	COG0022	dehydrogenase e1 component
OU987_RS04105	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU987_RS04110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU987_RS04115	COG3284	Transcriptional regulator
OU987_RS04125	COG1486	melibiose metabolic process
OU987_RS04130	COG1737	Transcriptional regulator
OU987_RS04135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS04135	COG1263	PTS System
OU987_RS04140	COG5434	Belongs to the glycosyl hydrolase 28 family
OU987_RS04145	COG5434	Belongs to the glycosyl hydrolase 28 family
OU987_RS04150	COG1132	(ABC) transporter
OU987_RS04155	COG1132	(ABC) transporter
OU987_RS04160	COG2259	Doxx family
OU987_RS04165	COG2514	catechol 2,3-dioxygenase activity
OU987_RS04180	COG1695	Transcriptional regulator
OU987_RS04185	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU987_RS04190	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OU987_RS04195	COG3848	Pyruvate phosphate dikinase
OU987_RS04195	COG0574	Belongs to the PEP-utilizing enzyme family
OU987_RS04200	COG2732	(Barnase) inhibitor
OU987_RS04205	COG2318	DinB family
OU987_RS04210	COG2814	Major facilitator Superfamily
OU987_RS04215	COG1846	Transcriptional regulator
OU987_RS04220	COG0392	lysyltransferase activity
OU987_RS04220	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OU987_RS04225	COG0384	phenazine biosynthesis protein PhzF
OU987_RS04230	COG0778	Nitroreductase
OU987_RS04245	COG1090	epimerase
OU987_RS04260	COG2814	Major facilitator Superfamily
OU987_RS04270	COG3591	Belongs to the peptidase S1B family
OU987_RS04285	COG3103	Sh3 type 3 domain protein
OU987_RS04290	COG5658	integral membrane protein
OU987_RS04295	COG0596	Alpha beta hydrolase
OU987_RS04300	COG0463	Glycosyl transferase, family 2
OU987_RS04305	COG4485	Bacterial membrane protein, YfhO
OU987_RS04310	COG1988	membrane-bound metal-dependent
OU987_RS04315	COG1194	a g-specific adenine glycosylase
OU987_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS04345	COG1132	(ABC) transporter
OU987_RS04350	COG4129	membrane
OU987_RS04360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OU987_RS04365	COG0735	belongs to the Fur family
OU987_RS04480	COG3340	Belongs to the peptidase S51 family
OU987_RS04490	COG0277	FAD linked oxidase domain protein
OU987_RS04500	COG0747	negative chemotaxis
OU987_RS04505	COG0601	transmembrane transport
OU987_RS04510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU987_RS04515	COG0444	Belongs to the ABC transporter superfamily
OU987_RS04520	COG4608	Belongs to the ABC transporter superfamily
OU987_RS04525	COG0753	catalase activity
OU987_RS04535	COG1116	anion transmembrane transporter activity
OU987_RS04540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OU987_RS04545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OU987_RS04565	COG1476	TRANSCRIPTIONal
OU987_RS04575	COG3382	B3 4 domain protein
OU987_RS04580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OU987_RS04590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OU987_RS04595	COG0789	Transcriptional regulator
OU987_RS04600	COG1664	Polymer-forming cytoskeletal
OU987_RS04605	COG1664	Polymer-forming cytoskeletal
OU987_RS04610	COG2766	serine protein kinase
OU987_RS04620	COG1846	Transcriptional regulator
OU987_RS04625	COG1566	PFAM secretion protein HlyD family protein
OU987_RS04630	COG2814	Major facilitator Superfamily
OU987_RS04635	COG0655	NAD(P)H dehydrogenase (quinone) activity
OU987_RS04650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU987_RS04655	COG1278	Cold shock
OU987_RS04660	COG1464	Belongs to the NlpA lipoprotein family
OU987_RS04665	COG3706	GGDEF domain
OU987_RS04670	COG1823	symporter activity
OU987_RS04690	COG5577	PFAM Coat F domain
OU987_RS04695	COG0737	Belongs to the 5'-nucleotidase family
OU987_RS04695	COG1525	nuclease
OU987_RS04695	COG4085	toxin activity
OU987_RS04700	COG3764	Sortase (surface protein transpeptidase)
OU987_RS04705	COG0564	pseudouridine synthase activity
OU987_RS04715	COG0517	IMP dehydrogenase activity
OU987_RS04720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OU987_RS04725	COG3153	acetyltransferase
OU987_RS04725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OU987_RS04730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OU987_RS04735	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OU987_RS04740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OU987_RS04750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OU987_RS04755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OU987_RS04760	COG4585	Histidine kinase
OU987_RS04760	COG2203	Gaf domain
OU987_RS04765	COG2197	response regulator
OU987_RS04770	COG0431	NADPH-dependent FMN reductase
OU987_RS04785	COG1388	LysM domain
OU987_RS04785	COG0791	NLP P60 protein
OU987_RS04790	COG1959	2 iron, 2 sulfur cluster binding
OU987_RS04800	COG2719	SpoVR family
OU987_RS04805	COG1785	Belongs to the alkaline phosphatase family
OU987_RS04810	COG0791	NLP P60 protein
OU987_RS04810	COG1388	LysM domain
OU987_RS04815	COG0583	DNA-binding transcription factor activity
OU987_RS04820	COG0372	Belongs to the citrate synthase family
OU987_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS04830	COG0531	amino acid
OU987_RS04835	COG0733	neurotransmitter:sodium symporter activity
OU987_RS04850	COG1595	DNA-templated transcription, initiation
OU987_RS04855	COG0204	Acyl-transferase
OU987_RS04860	COG1253	flavin adenine dinucleotide binding
OU987_RS04865	COG0789	Transcriptional regulator
OU987_RS04870	COG0436	Aminotransferase
OU987_RS04875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OU987_RS04880	COG1253	flavin adenine dinucleotide binding
OU987_RS04885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OU987_RS04890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OU987_RS04895	COG0584	glycerophosphoryl diester phosphodiesterase
OU987_RS04905	COG0668	transmembrane transport
OU987_RS04910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OU987_RS04915	COG0726	polysaccharide deacetylase
OU987_RS04920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU987_RS04925	COG3226	Transcriptional regulator
OU987_RS04935	COG0589	response to stress
OU987_RS04940	COG1132	(ABC) transporter
OU987_RS04945	COG1132	(ABC) transporter
OU987_RS04950	COG0702	epimerase
OU987_RS04970	COG0189	ligase activity
OU987_RS04975	COG0189	ligase activity
OU987_RS04990	COG4335	DNA alkylation repair
OU987_RS04995	COG0561	phosphatase activity
OU987_RS05000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OU987_RS05010	COG0475	glutathione-regulated potassium exporter activity
OU987_RS05015	COG0490	domain, Protein
OU987_RS05025	COG1024	Enoyl-CoA hydratase
OU987_RS05035	COG4152	abc transporter atp-binding protein
OU987_RS05040	COG1668	transmembrane transport
OU987_RS05045	COG0420	3'-5' exonuclease activity
OU987_RS05050	COG4717	serine-type aminopeptidase activity
OU987_RS05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OU987_RS05100	COG4980	gas vesicle protein
OU987_RS05115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OU987_RS05120	COG0537	adenosine 5'-monophosphoramidase activity
OU987_RS05125	COG1131	(ABC) transporter
OU987_RS05130	COG4473	ABC transporter
OU987_RS05140	COG1473	amidohydrolase
OU987_RS05145	COG3069	C4-dicarboxylate transmembrane transporter activity
OU987_RS05150	COG2329	Antibiotic biosynthesis monooxygenase
OU987_RS05155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU987_RS05165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OU987_RS05170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OU987_RS05175	COG1309	transcriptional regulator
OU987_RS05180	COG1511	domain protein
OU987_RS05185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU987_RS05195	COG1363	Peptidase, m42
OU987_RS05200	COG1301	dicarboxylic acid transport
OU987_RS05210	COG1234	tRNA 3'-trailer cleavage
OU987_RS05215	COG0095	Lipoate-protein ligase
OU987_RS05220	COG0702	epimerase
OU987_RS05225	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS05235	COG0501	Belongs to the peptidase M48B family
OU987_RS05240	COG1404	Belongs to the peptidase S8 family
OU987_RS05245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OU987_RS05250	COG0406	alpha-ribazole phosphatase activity
OU987_RS05255	COG0183	Belongs to the thiolase family
OU987_RS05260	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS05265	COG1268	BioY protein
OU987_RS05270	COG0840	transmembrane signaling receptor activity
OU987_RS05275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OU987_RS05275	COG0723	plastoquinol--plastocyanin reductase activity
OU987_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS05290	COG4903	ComK protein
OU987_RS05300	COG5646	InterPro IPR014922
OU987_RS05320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU987_RS05335	COG0398	Pfam SNARE associated Golgi protein
OU987_RS05340	COG0681	Belongs to the peptidase S26 family
OU987_RS05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OU987_RS05350	COG1846	Transcriptional regulator
OU987_RS05355	COG3180	Ammonia monooxygenase
OU987_RS05360	COG2814	Major facilitator Superfamily
OU987_RS05370	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OU987_RS05375	COG2323	membrane
OU987_RS05390	COG0420	3'-5' exonuclease activity
OU987_RS05395	COG0419	ATPase involved in DNA repair
OU987_RS05400	COG1403	HNH endonuclease
OU987_RS05440	COG0179	Fumarylacetoacetate (FAA) hydrolase
OU987_RS05455	COG0367	asparagine synthase
OU987_RS05460	COG1562	ergosterol biosynthetic process
OU987_RS05465	COG0534	Mate efflux family protein
OU987_RS05470	COG1917	Cupin 2, conserved barrel domain protein
OU987_RS05470	COG2207	Transcriptional regulator
OU987_RS05480	COG2318	DinB family
OU987_RS05485	COG1279	arginine transmembrane transporter activity
OU987_RS05490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS05495	COG1357	PFAM Pentapeptide repeats (8 copies)
OU987_RS05500	COG2153	protein acetylation
OU987_RS05505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OU987_RS05505	COG0646	methionine synthase
OU987_RS05515	COG2996	Protein conserved in bacteria
OU987_RS05520	COG1744	ABC transporter substrate-binding protein PnrA-like
OU987_RS05525	COG0840	transmembrane signaling receptor activity
OU987_RS05530	COG2124	cytochrome p450
OU987_RS05540	COG1307	EDD domain protein, DegV family
OU987_RS05545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS05565	COG0561	phosphatase activity
OU987_RS05570	COG1073	alpha beta
OU987_RS05575	COG2151	metal-sulfur cluster biosynthetic enzyme
OU987_RS05585	COG0277	FAD linked oxidase domain protein
OU987_RS05590	COG2271	Major facilitator Superfamily
OU987_RS05600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OU987_RS05610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OU987_RS05615	COG0505	Belongs to the CarA family
OU987_RS05620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OU987_RS05625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OU987_RS05640	COG2267	carboxylic ester hydrolase activity
OU987_RS05650	COG1744	ABC transporter substrate-binding protein PnrA-like
OU987_RS05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU987_RS05670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OU987_RS05675	COG5504	Zn-dependent protease
OU987_RS05680	COG0444	Belongs to the ABC transporter superfamily
OU987_RS05685	COG4608	Belongs to the ABC transporter superfamily
OU987_RS05695	COG0601	transmembrane transport
OU987_RS05700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU987_RS05710	COG0180	Tryptophanyl-tRNA synthetase
OU987_RS05715	COG4166	transmembrane transport
OU987_RS05720	COG0601	transmembrane transport
OU987_RS05725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU987_RS05730	COG0444	Belongs to the ABC transporter superfamily
OU987_RS05735	COG4608	Belongs to the ABC transporter superfamily
OU987_RS05745	COG0456	acetyltransferase
OU987_RS05750	COG1393	Belongs to the ArsC family
OU987_RS05755	COG0861	Integral membrane protein TerC family
OU987_RS05760	COG4862	establishment of competence for transformation
OU987_RS05765	COG4469	Competence protein
OU987_RS05770	COG1164	Oligoendopeptidase f
OU987_RS05780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OU987_RS05785	COG2346	COG2346, Truncated hemoglobins
OU987_RS05790	COG0741	lytic transglycosylase activity
OU987_RS05795	COG4116	CYTH
OU987_RS05805	COG2357	RelA SpoT domain protein
OU987_RS05810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OU987_RS05815	COG0564	pseudouridine synthase activity
OU987_RS05825	COG0475	glutathione-regulated potassium exporter activity
OU987_RS05825	COG0569	domain protein
OU987_RS05830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OU987_RS05835	COG0352	thiamine-phosphate diphosphorylase activity
OU987_RS05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OU987_RS05845	COG2104	thiamine diphosphate biosynthetic process
OU987_RS05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OU987_RS05860	COG0351	phosphomethylpyrimidine kinase
OU987_RS05865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OU987_RS05920	COG0210	DNA helicase
OU987_RS05940	COG1131	(ABC) transporter
OU987_RS05950	COG2153	protein acetylation
OU987_RS05960	COG2382	esterase
OU987_RS05965	COG0626	cystathionine gamma-synthase activity
OU987_RS05970	COG0626	cystathionine gamma-synthase activity
OU987_RS06000	COG5444	nuclease activity
OU987_RS06010	COG0346	lactoylglutathione lyase activity
OU987_RS06015	COG2367	Beta-lactamase
OU987_RS06020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OU987_RS06025	COG0477	Major facilitator Superfamily
OU987_RS06030	COG1846	Transcriptional regulator
OU987_RS06040	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OU987_RS06045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU987_RS06050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OU987_RS06055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS06055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS06060	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU987_RS06070	COG1349	DNA-binding transcription factor activity
OU987_RS06090	COG1285	pathogenesis
OU987_RS06105	COG2205	protein histidine kinase activity
OU987_RS06115	COG3383	formate dehydrogenase (NAD+) activity
OU987_RS06120	COG2427	Protein of unknown function (DUF1641)
OU987_RS06125	COG2124	cytochrome p450
OU987_RS06130	COG1819	glycosyl
OU987_RS06140	COG1587	Uroporphyrinogen-III synthase
OU987_RS06145	COG0390	transport system, permease component
OU987_RS06150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OU987_RS06155	COG0697	spore germination
OU987_RS06160	COG4297	protein containing double-stranded beta helix domain
OU987_RS06170	COG1252	NADH dehydrogenase
OU987_RS06180	COG2211	Major facilitator Superfamily
OU987_RS06185	COG1609	Transcriptional regulator
OU987_RS06190	COG0246	Mannitol dehydrogenase
OU987_RS06195	COG2721	sulfolactate sulfo-lyase activity
OU987_RS06200	COG0745	RESPONSE REGULATOR receiver
OU987_RS06205	COG2205	protein histidine kinase activity
OU987_RS06205	COG2770	Histidine kinase
OU987_RS06225	COG4585	Histidine kinase
OU987_RS06230	COG2197	response regulator
OU987_RS06265	COG0730	response to heat
OU987_RS06270	COG2318	DinB family
OU987_RS06275	COG0457	Tetratricopeptide repeat
OU987_RS06285	COG1388	LysM domain
OU987_RS06285	COG5632	N-Acetylmuramoyl-L-alanine amidase
OU987_RS06285	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS06295	COG4195	phage-related replication protein
OU987_RS06300	COG2856	Zn peptidase
OU987_RS06305	COG1396	sequence-specific DNA binding
OU987_RS06315	COG1522	sequence-specific DNA binding
OU987_RS06320	COG1484	DNA-dependent DNA replication
OU987_RS06340	COG1595	DNA-templated transcription, initiation
OU987_RS06345	COG5484	DNA packaging
OU987_RS06345	COG3728	DNA packaging
OU987_RS06350	COG1783	phage Terminase large subunit
OU987_RS06355	COG5518	Phage portal protein
OU987_RS06360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OU987_RS06365	COG4653	Phage capsid family
OU987_RS06415	COG3953	SLT domain
OU987_RS06415	COG5412	phage tail tape measure protein
OU987_RS06415	COG3953	SLT domain
OU987_RS06415	COG5412	phage tail tape measure protein
OU987_RS06415	COG3953	SLT domain
OU987_RS06415	COG5412	phage tail tape measure protein
OU987_RS06420	COG1652	LysM domain
OU987_RS06425	COG4193	domain, Protein
OU987_RS06435	COG3628	GPW Gp25 family protein
OU987_RS06440	COG3299	homolog of phage Mu protein gp47
OU987_RS06445	COG3778	Protein conserved in bacteria
OU987_RS06485	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS06485	COG5632	N-Acetylmuramoyl-L-alanine amidase
OU987_RS06505	COG0306	phosphate transporter
OU987_RS06510	COG1392	Phosphate transport regulator
OU987_RS06515	COG0531	amino acid
OU987_RS06520	COG0346	lactoylglutathione lyase activity
OU987_RS06525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OU987_RS06530	COG0463	Glycosyl transferase, family 2
OU987_RS06540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU987_RS06545	COG0477	Major facilitator Superfamily
OU987_RS06550	COG2362	D-Aminopeptidase
OU987_RS06555	COG0601	transmembrane transport
OU987_RS06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU987_RS06565	COG0444	Belongs to the ABC transporter superfamily
OU987_RS06570	COG4166	transmembrane transport
OU987_RS06575	COG1619	proteins homologs of microcin C7 resistance protein MccF
OU987_RS06580	COG4948	Mandelate Racemase Muconate Lactonizing
OU987_RS06585	COG0791	NLP P60 protein
OU987_RS06590	COG4608	Belongs to the ABC transporter superfamily
OU987_RS06595	COG2706	6-phosphogluconolactonase activity
OU987_RS06600	COG1834	amidinotransferase
OU987_RS06605	COG1607	acyl-coa hydrolase
OU987_RS06610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU987_RS06615	COG2076	Multidrug Resistance protein
OU987_RS06620	COG2076	Multidrug Resistance protein
OU987_RS06625	COG0788	formyltetrahydrofolate deformylase activity
OU987_RS06630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OU987_RS06640	COG1764	response to oxidative stress
OU987_RS06645	COG1846	Transcriptional regulator
OU987_RS06650	COG1764	response to oxidative stress
OU987_RS06665	COG0463	Glycosyl transferase, family 2
OU987_RS06665	COG0457	Tetratricopeptide repeat
OU987_RS06690	COG1404	Belongs to the peptidase S8 family
OU987_RS06695	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS06700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OU987_RS06705	COG1122	ATPase activity
OU987_RS06710	COG4721	ABC-type cobalt transport system, permease component
OU987_RS06715	COG3858	chitin binding
OU987_RS06715	COG1388	LysM domain
OU987_RS06725	COG2239	Acts as a magnesium transporter
OU987_RS06730	COG0789	Transcriptional regulator
OU987_RS06745	COG1846	Transcriptional regulator
OU987_RS06750	COG0726	polysaccharide deacetylase
OU987_RS06755	COG1793	dna ligase
OU987_RS06755	COG3285	dna ligase
OU987_RS06760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OU987_RS06765	COG0586	Pfam SNARE associated Golgi protein
OU987_RS06775	COG1191	sigma factor activity
OU987_RS06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OU987_RS06805	COG2323	membrane
OU987_RS06815	COG3594	Acyltransferase
OU987_RS06820	COG5002	protein histidine kinase activity
OU987_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OU987_RS06845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OU987_RS06850	COG0436	Aminotransferase
OU987_RS06880	COG3852	Histidine kinase
OU987_RS06885	COG1846	Transcriptional regulator
OU987_RS06890	COG1360	Flagellar Motor Protein
OU987_RS06895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OU987_RS06900	COG0542	response to heat
OU987_RS06905	COG3949	Membrane
OU987_RS06920	COG0720	synthase
OU987_RS06925	COG0602	queuosine metabolic process
OU987_RS06940	COG1733	regulation of RNA biosynthetic process
OU987_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS06960	COG4873	Protein conserved in bacteria
OU987_RS06970	COG3773	Cell wall hydrolase
OU987_RS06975	COG2244	polysaccharide biosynthetic process
OU987_RS06980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS06985	COG2217	Heavy metal translocating P-type atpase
OU987_RS06990	COG0006	proline dipeptidase activity
OU987_RS07000	COG1609	Transcriptional regulator
OU987_RS07005	COG3711	transcriptional antiterminator
OU987_RS07010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS07010	COG2190	(PTS) system
OU987_RS07010	COG1263	PTS System
OU987_RS07015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS07020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OU987_RS07030	COG1533	DNA photolyase activity
OU987_RS07035	COG0840	transmembrane signaling receptor activity
OU987_RS07040	COG2084	Dehydrogenase
OU987_RS07045	COG2340	Cysteine-rich secretory protein family
OU987_RS07050	COG0768	penicillin binding
OU987_RS07055	COG4191	Histidine kinase
OU987_RS07060	COG0436	Aminotransferase
OU987_RS07070	COG0784	Response regulator, receiver
OU987_RS07070	COG0835	chemotaxis
OU987_RS07080	COG2814	Major facilitator Superfamily
OU987_RS07085	COG1376	ErfK ybiS ycfS ynhG family protein
OU987_RS07090	COG1408	metallophosphoesterase
OU987_RS07095	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS07105	COG2200	EAL domain
OU987_RS07110	COG4703	Protein of unknown function (DUF1797)
OU987_RS07115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OU987_RS07125	COG0517	IMP dehydrogenase activity
OU987_RS07130	COG0583	DNA-binding transcription factor activity
OU987_RS07135	COG0716	FMN binding
OU987_RS07145	COG0716	FMN binding
OU987_RS07165	COG0668	transmembrane transport
OU987_RS07170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS07190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OU987_RS07195	COG0303	'Molybdopterin
OU987_RS07200	COG1763	Mo-molybdopterin cofactor biosynthetic process
OU987_RS07205	COG0314	molybdopterin synthase activity
OU987_RS07210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OU987_RS07220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OU987_RS07225	COG1136	(ABC) transporter
OU987_RS07230	COG0577	efflux transmembrane transporter activity
OU987_RS07235	COG1349	DNA-binding transcription factor activity
OU987_RS07240	COG1105	Belongs to the carbohydrate kinase PfkB family
OU987_RS07245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU987_RS07245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU987_RS07245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS07250	COG0681	Belongs to the peptidase S26 family
OU987_RS07260	COG0488	(ABC) transporter
OU987_RS07265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OU987_RS07270	COG2309	aminopeptidase activity
OU987_RS07280	COG1077	Cell shape determining protein MreB Mrl
OU987_RS07285	COG2002	toxin-antitoxin pair type II binding
OU987_RS07290	COG3852	Histidine kinase
OU987_RS07295	COG2105	PFAM AIG2 family protein
OU987_RS07295	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OU987_RS07300	COG0569	domain protein
OU987_RS07310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OU987_RS07320	COG0561	phosphatase activity
OU987_RS07325	COG0242	peptide deformylase activity
OU987_RS07335	COG0497	DNA recombination
OU987_RS07340	COG2070	2-Nitropropane dioxygenase
OU987_RS07340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OU987_RS07345	COG4221	oxidoreductase activity
OU987_RS07345	COG3321	synthase
OU987_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS07345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS07350	COG4221	oxidoreductase activity
OU987_RS07350	COG0300	oxidoreductase activity
OU987_RS07350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS07350	COG3321	synthase
OU987_RS07355	COG4221	oxidoreductase activity
OU987_RS07355	COG3321	synthase
OU987_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS07355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS07360	COG3321	synthase
OU987_RS07360	COG4221	oxidoreductase activity
OU987_RS07360	COG0300	oxidoreductase activity
OU987_RS07365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS07365	COG0300	oxidoreductase activity
OU987_RS07365	COG3321	synthase
OU987_RS07365	COG4221	oxidoreductase activity
OU987_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS07370	COG3321	synthase
OU987_RS07370	COG4221	oxidoreductase activity
OU987_RS07370	COG0300	oxidoreductase activity
OU987_RS07375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS07375	COG3321	synthase
OU987_RS07375	COG4221	oxidoreductase activity
OU987_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS07380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU987_RS07385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU987_RS07390	COG0022	dehydrogenase e1 component
OU987_RS07395	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU987_RS07400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU987_RS07405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS07420	COG1982	Orn Lys Arg decarboxylase major
OU987_RS07440	COG0483	inositol monophosphate 1-phosphatase activity
OU987_RS07450	COG3227	Zinc metalloprotease (Elastase)
OU987_RS07455	COG1595	DNA-templated transcription, initiation
OU987_RS07475	COG1217	gtp-binding protein TYPA
OU987_RS07485	COG4896	Protein conserved in bacteria
OU987_RS07495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OU987_RS07500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OU987_RS07505	COG2066	Belongs to the glutaminase family
OU987_RS07515	COG0772	Belongs to the SEDS family
OU987_RS07520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OU987_RS07535	COG2010	Cytochrome c
OU987_RS07535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OU987_RS07540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OU987_RS07545	COG1845	cytochrome c oxidase, subunit III
OU987_RS07550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OU987_RS07555	COG3336	cytochrome c oxidase
OU987_RS07565	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OU987_RS07570	COG2340	Cysteine-rich secretory protein family
OU987_RS07585	COG3679	Belongs to the UPF0342 family
OU987_RS07595	COG0742	ribosomal rna small subunit methyltransferase
OU987_RS07605	COG3314	Sporulation integral membrane protein YlbJ
OU987_RS07610	COG1752	Esterase of the alpha-beta hydrolase superfamily
OU987_RS07615	COG3480	Lon protease (S16) C-terminal proteolytic domain
OU987_RS07625	COG1399	metal-binding, possibly nucleic acid-binding protein
OU987_RS07645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OU987_RS07665	COG4839	cell division protein FtsL
OU987_RS07670	COG0768	penicillin binding
OU987_RS07675	COG0768	penicillin binding
OU987_RS07695	COG0772	Belongs to the SEDS family
OU987_RS07710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OU987_RS07715	COG0849	cell division
OU987_RS07720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OU987_RS07725	COG4412	M6 family metalloprotease domain protein
OU987_RS07725	COG1404	Belongs to the peptidase S8 family
OU987_RS07735	COG1191	sigma factor activity
OU987_RS07740	COG1191	sigma factor activity
OU987_RS07745	COG1119	ATPase activity
OU987_RS07750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU987_RS07755	COG1873	PFAM PRC-barrel domain
OU987_RS07760	COG1496	oxidoreductase activity
OU987_RS07765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OU987_RS07775	COG0762	integral membrane protein
OU987_RS07780	COG2302	S4 RNA-binding domain
OU987_RS07785	COG3599	regulation of cell shape
OU987_RS07790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OU987_RS07795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU987_RS07805	COG0564	pseudouridine synthase activity
OU987_RS07815	COG2233	PERMEase
OU987_RS07825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OU987_RS07830	COG0505	Belongs to the CarA family
OU987_RS07835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OU987_RS07850	COG0284	orotidine-5'-phosphate decarboxylase activity
OU987_RS07855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OU987_RS07865	COG0306	phosphate transporter
OU987_RS07880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OU987_RS07885	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OU987_RS07890	COG1648	precorrin-2 dehydrogenase activity
OU987_RS07900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OU987_RS07905	COG1561	YicC-like family, N-terminal region
OU987_RS07915	COG0194	GDP metabolic process
OU987_RS07925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OU987_RS07930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OU987_RS07935	COG0242	peptide deformylase activity
OU987_RS07945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OU987_RS07945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OU987_RS07955	COG0631	protein serine/threonine phosphatase activity
OU987_RS07960	COG2815	serine threonine protein kinase
OU987_RS07960	COG0515	serine threonine protein kinase
OU987_RS07970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OU987_RS07975	COG1564	THIamine pyrophosphokinase
OU987_RS07990	COG1302	Protein conserved in bacteria
OU987_RS07995	COG1461	Dihydroxyacetone kinase
OU987_RS08000	COG1760	l-serine dehydratase
OU987_RS08005	COG1760	l-serine dehydratase
OU987_RS08010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OU987_RS08025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OU987_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS08045	COG1196	nuclear chromosome segregation
OU987_RS08050	COG0552	protein localization to endoplasmic reticulum
OU987_RS08065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OU987_RS08075	COG1837	Belongs to the UPF0109 family
OU987_RS08100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OU987_RS08115	COG2257	FlhB HrpN YscU SpaS Family
OU987_RS08125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OU987_RS08130	COG0758	DNA mediated transformation
OU987_RS08135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OU987_RS08145	COG4974	Belongs to the 'phage' integrase family
OU987_RS08165	COG1815	bacterial-type flagellum-dependent cell motility
OU987_RS08170	COG1558	bacterial-type flagellum-dependent cell motility
OU987_RS08175	COG1677	Flagellar hook-basal body complex protein FliE
OU987_RS08180	COG1766	The M ring may be actively involved in energy transduction
OU987_RS08185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU987_RS08190	COG1317	bacterial-type flagellum organization
OU987_RS08195	COG1157	protein secretion by the type III secretion system
OU987_RS08200	COG2882	bacterial-type flagellum organization
OU987_RS08205	COG3334	PFAM MgtE intracellular
OU987_RS08210	COG3144	bacterial-type flagellum assembly
OU987_RS08215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OU987_RS08220	COG4786	Flagellar basal body rod
OU987_RS08225	COG1582	Flagellar protein (FlbD)
OU987_RS08230	COG1580	Controls the rotational direction of flagella during chemotaxis
OU987_RS08235	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU987_RS08240	COG1776	CheC inhibitor of MCP methylation
OU987_RS08240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU987_RS08245	COG2201	protein-glutamate methylesterase activity
OU987_RS08250	COG3190	flagellar
OU987_RS08255	COG1338	Plays a role in the flagellum-specific transport system
OU987_RS08260	COG1987	bacterial-type flagellum assembly
OU987_RS08265	COG1684	flagellar biosynthetic protein fliR
OU987_RS08270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OU987_RS08275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OU987_RS08280	COG1419	protein localization to endoplasmic reticulum
OU987_RS08285	COG0455	bacterial-type flagellum organization
OU987_RS08290	COG2201	protein-glutamate methylesterase activity
OU987_RS08295	COG0643	Histidine kinase
OU987_RS08295	COG2198	Histidine kinase
OU987_RS08300	COG0835	chemotaxis
OU987_RS08305	COG1776	CheC inhibitor of MCP methylation
OU987_RS08315	COG1191	sigma factor activity
OU987_RS08345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OU987_RS08350	COG4589	Belongs to the CDS family
OU987_RS08360	COG0750	zinc metalloprotease
OU987_RS08380	COG0195	Participates in both transcription termination and antitermination
OU987_RS08385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OU987_RS08390	COG1358	cellular component organization or biogenesis
OU987_RS08400	COG1550	Protein conserved in bacteria
OU987_RS08415	COG0196	riboflavin kinase activity
OU987_RS08430	COG0726	polysaccharide deacetylase
OU987_RS08435	COG0612	Peptidase, M16
OU987_RS08440	COG1873	PFAM PRC-barrel domain
OU987_RS08445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU987_RS08450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OU987_RS08455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OU987_RS08460	COG0527	aspartate kinase activity
OU987_RS08470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OU987_RS08475	COG0740	serine-type endopeptidase activity
OU987_RS08485	COG1674	ftsk spoiiie
OU987_RS08485	COG4980	gas vesicle protein
OU987_RS08490	COG2188	Transcriptional regulator
OU987_RS08495	COG2814	Major facilitator Superfamily
OU987_RS08500	COG1846	Transcriptional regulator
OU987_RS08505	COG1033	growth of symbiont in host cell
OU987_RS08505	COG2409	Drug exporters of the RND superfamily
OU987_RS08510	COG0612	Peptidase, M16
OU987_RS08515	COG0612	Peptidase, M16
OU987_RS08520	COG0300	oxidoreductase activity
OU987_RS08535	COG1426	Protein conserved in bacteria
OU987_RS08540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OU987_RS08555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU987_RS08565	COG1692	metallophosphoesterase
OU987_RS08570	COG2359	stage V sporulation protein S
OU987_RS08590	COG4550	Control of competence regulator ComK, YlbF/YmcA
OU987_RS08635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS08640	COG3425	synthase
OU987_RS08645	COG1024	Enoyl-CoA hydratase
OU987_RS08650	COG1024	Enoyl-CoA hydratase
OU987_RS08655	COG0300	oxidoreductase activity
OU987_RS08655	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS08655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS08655	COG3321	synthase
OU987_RS08660	COG3321	synthase
OU987_RS08660	COG0300	oxidoreductase activity
OU987_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS08660	COG4221	oxidoreductase activity
OU987_RS08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS08665	COG3321	synthase
OU987_RS08665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS08665	COG3321	synthase
OU987_RS08665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS08665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS08665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS08670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS08670	COG4221	oxidoreductase activity
OU987_RS08670	COG3321	synthase
OU987_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS08675	COG3321	synthase
OU987_RS08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS08675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OU987_RS08675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OU987_RS08680	COG2124	cytochrome p450
OU987_RS08685	COG3209	COG3209 Rhs family protein
OU987_RS08690	COG3619	membrane
OU987_RS08700	COG1404	Belongs to the peptidase S8 family
OU987_RS08710	COG4195	phage-related replication protein
OU987_RS08715	COG1764	response to oxidative stress
OU987_RS08725	COG2076	Multidrug Resistance protein
OU987_RS08765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OU987_RS08770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OU987_RS08775	COG4112	unkown
OU987_RS08780	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS08785	COG0464	growth
OU987_RS08790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OU987_RS08795	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OU987_RS08800	COG0789	Transcriptional regulator
OU987_RS08805	COG0174	glutamine synthetase
OU987_RS08850	COG2211	Major facilitator Superfamily
OU987_RS08855	COG3507	Belongs to the glycosyl hydrolase 43 family
OU987_RS08870	COG1070	Carbohydrate kinase
OU987_RS08875	COG0574	Belongs to the PEP-utilizing enzyme family
OU987_RS08875	COG3848	Pyruvate phosphate dikinase
OU987_RS08895	COG2318	DinB family
OU987_RS08900	COG1064	alcohol dehydrogenase
OU987_RS08905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OU987_RS08905	COG4451	ribulose bisphosphate carboxylase, small
OU987_RS08950	COG3397	chitin binding
OU987_RS08970	COG5434	Belongs to the glycosyl hydrolase 28 family
OU987_RS08975	COG0756	dUTP diphosphatase activity
OU987_RS08985	COG4195	phage-related replication protein
OU987_RS09020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OU987_RS09030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OU987_RS09050	COG0785	Cytochrome C biogenesis protein
OU987_RS09055	COG2201	protein-glutamate methylesterase activity
OU987_RS09060	COG4846	Membrane protein involved in cytochrome C biogenesis
OU987_RS09070	COG0071	Belongs to the small heat shock protein (HSP20) family
OU987_RS09085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OU987_RS09090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS09110	COG0824	Thioesterase
OU987_RS09120	COG4841	protein insertion into membrane
OU987_RS09130	COG1832	CoA-binding protein
OU987_RS09135	COG0187	DNA topoisomerase II activity
OU987_RS09140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OU987_RS09155	COG1115	amino acid carrier protein
OU987_RS09165	COG1063	alcohol dehydrogenase
OU987_RS09170	COG0800	Aldolase
OU987_RS09175	COG1312	Catalyzes the dehydration of D-mannonate
OU987_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS09185	COG1609	Transcriptional regulator
OU987_RS09190	COG2271	Major facilitator Superfamily
OU987_RS09235	COG2205	protein histidine kinase activity
OU987_RS09240	COG0745	RESPONSE REGULATOR receiver
OU987_RS09250	COG3507	Belongs to the glycosyl hydrolase 43 family
OU987_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS09280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OU987_RS09285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OU987_RS09290	COG2610	gluconate transmembrane transporter activity
OU987_RS09295	COG2124	cytochrome p450
OU987_RS09315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OU987_RS09325	COG2246	polysaccharide biosynthetic process
OU987_RS09335	COG0586	Pfam SNARE associated Golgi protein
OU987_RS09340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OU987_RS09345	COG1024	Enoyl-CoA hydratase
OU987_RS09350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OU987_RS09355	COG0511	ligase activity, forming carbon-carbon bonds
OU987_RS09360	COG0439	Biotin carboxylase
OU987_RS09365	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS09370	COG1960	acyl-CoA dehydrogenase activity
OU987_RS09375	COG1649	PFAM Uncharacterised BCR, COG1649
OU987_RS09385	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OU987_RS09385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS09400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS09405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS09410	COG2027	D-alanyl-D-alanine carboxypeptidase
OU987_RS09415	COG2017	converts alpha-aldose to the beta-anomer
OU987_RS09420	COG0534	Mate efflux family protein
OU987_RS09435	COG0582	viral genome integration into host DNA
OU987_RS09440	COG0166	Belongs to the GPI family
OU987_RS09445	COG0405	Gamma-glutamyltransferase
OU987_RS09450	COG2814	Major facilitator Superfamily
OU987_RS09455	COG0640	Transcriptional regulator
OU987_RS09460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OU987_RS09470	COG0604	alcohol dehydrogenase
OU987_RS09475	COG0493	'glutamate synthase
OU987_RS09480	COG0067	glutamate synthase
OU987_RS09480	COG0070	glutamate synthase
OU987_RS09480	COG0069	glutamate synthase activity
OU987_RS09485	COG0583	DNA-binding transcription factor activity
OU987_RS09490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OU987_RS09505	COG0300	oxidoreductase activity
OU987_RS09510	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OU987_RS09520	COG2814	Major facilitator Superfamily
OU987_RS09525	COG1070	Carbohydrate kinase
OU987_RS09530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OU987_RS09535	COG0243	molybdopterin cofactor binding
OU987_RS09565	COG5444	nuclease activity
OU987_RS09570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU987_RS09575	COG2207	Transcriptional regulator
OU987_RS09575	COG0662	Cupin 2, conserved barrel domain protein
OU987_RS09580	COG1309	transcriptional regulator
OU987_RS09585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS09595	COG0640	Transcriptional regulator
OU987_RS09600	COG0741	lytic transglycosylase activity
OU987_RS09605	COG2322	membrane
OU987_RS09620	COG1619	proteins homologs of microcin C7 resistance protein MccF
OU987_RS09630	COG1388	LysM domain
OU987_RS09630	COG3584	3D domain protein
OU987_RS09635	COG0514	ATP-dependent DNA helicase (RecQ)
OU987_RS09645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OU987_RS09650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU987_RS09665	COG0071	Belongs to the small heat shock protein (HSP20) family
OU987_RS09695	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS09700	COG1657	PFAM Prenyltransferase squalene oxidase
OU987_RS09705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OU987_RS09710	COG0733	neurotransmitter:sodium symporter activity
OU987_RS09715	COG0385	Bile acid
OU987_RS09720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS09725	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU987_RS09735	COG4548	von Willebrand factor, type A
OU987_RS09740	COG0714	Associated with various cellular activities
OU987_RS09745	COG2032	superoxide dismutase activity
OU987_RS09750	COG0791	NLP P60 protein
OU987_RS09750	COG1388	LysM domain
OU987_RS09755	COG1819	glycosyl
OU987_RS09760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OU987_RS09765	COG0534	Mate efflux family protein
OU987_RS09770	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS09775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU987_RS09780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU987_RS09790	COG2962	Rard protein
OU987_RS09805	COG1942	4-Oxalocrotonate Tautomerase
OU987_RS09815	COG1733	regulation of RNA biosynthetic process
OU987_RS09820	COG0778	Nitroreductase
OU987_RS09825	COG0400	carboxylic ester hydrolase activity
OU987_RS09830	COG0346	lactoylglutathione lyase activity
OU987_RS09840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU987_RS09850	COG2723	6-phospho-beta-galactosidase activity
OU987_RS09855	COG2188	Transcriptional regulator
OU987_RS09860	COG0793	Belongs to the peptidase S41A family
OU987_RS09860	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS09865	COG2226	methyltransferase
OU987_RS09875	COG1876	peptidase activity
OU987_RS09895	COG0671	phosphoesterase, PA-phosphatase related
OU987_RS09925	COG1509	lysine 2,3-aminomutase activity
OU987_RS09930	COG0456	acetyltransferase
OU987_RS09935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU987_RS09940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OU987_RS09945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OU987_RS09950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OU987_RS09955	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OU987_RS09965	COG0456	acetyltransferase
OU987_RS09970	COG0463	Glycosyl transferase, family 2
OU987_RS09985	COG4641	Protein conserved in bacteria
OU987_RS09995	COG1086	Polysaccharide biosynthesis protein
OU987_RS10030	COG0457	Tetratricopeptide repeat
OU987_RS10040	COG3391	amine dehydrogenase activity
OU987_RS10060	COG5444	nuclease activity
OU987_RS10065	COG4282	regulation of fungal-type cell wall biogenesis
OU987_RS10070	COG1525	nuclease
OU987_RS10095	COG1846	Transcriptional regulator
OU987_RS10100	COG4698	Protein conserved in bacteria
OU987_RS10105	COG2755	lipolytic protein G-D-S-L family
OU987_RS10110	COG1999	signal sequence binding
OU987_RS10120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OU987_RS10125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OU987_RS10130	COG1272	protein, Hemolysin III
OU987_RS10135	COG0204	Acyl-transferase
OU987_RS10140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OU987_RS10155	COG2136	Putative SAM-dependent methyltransferase
OU987_RS10155	COG2521	methyltransferase
OU987_RS10170	COG1413	lyase activity
OU987_RS10175	COG1418	mRNA catabolic process
OU987_RS10180	COG0386	Belongs to the glutathione peroxidase family
OU987_RS10190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OU987_RS10200	COG1278	Cold shock
OU987_RS10220	COG0328	RNA-DNA hybrid ribonuclease activity
OU987_RS10225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OU987_RS10230	COG0328	RNA-DNA hybrid ribonuclease activity
OU987_RS10240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU987_RS10255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OU987_RS10265	COG1755	Isoprenylcysteine carboxyl methyltransferase
OU987_RS10270	COG3424	synthase
OU987_RS10295	COG1335	isochorismatase
OU987_RS10305	COG2233	PERMEase
OU987_RS10315	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OU987_RS10320	COG1199	ATP-dependent helicase activity
OU987_RS10335	COG0116	Belongs to the methyltransferase superfamily
OU987_RS10365	COG3359	exonuclease
OU987_RS10370	COG1205	dead DEAH box helicase
OU987_RS10370	COG1111	helicase
OU987_RS10375	COG2190	(PTS) system
OU987_RS10380	COG0071	Belongs to the small heat shock protein (HSP20) family
OU987_RS10420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU987_RS10420	COG4499	WXG100 protein secretion system (Wss), protein YukC
OU987_RS10430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OU987_RS10435	COG3935	DnaD domain protein
OU987_RS10445	COG0436	Aminotransferase
OU987_RS10450	COG5353	protein conserved in bacteria
OU987_RS10460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OU987_RS10460	COG1199	ATP-dependent helicase activity
OU987_RS10490	COG0438	transferase activity, transferring glycosyl groups
OU987_RS10495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU987_RS10510	COG1694	Mazg nucleotide pyrophosphohydrolase
OU987_RS10515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS10530	COG4347	Protein of unknown function (DUF1405)
OU987_RS10535	COG2010	Cytochrome c
OU987_RS10535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OU987_RS10540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OU987_RS10545	COG0723	plastoquinol--plastocyanin reductase activity
OU987_RS10560	COG0457	Tetratricopeptide repeat
OU987_RS10570	COG0287	Prephenate dehydrogenase
OU987_RS10605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OU987_RS10610	COG4401	Chorismate mutase type I
OU987_RS10625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OU987_RS10630	COG0105	UTP biosynthetic process
OU987_RS10635	COG0142	geranyltranstransferase activity
OU987_RS10645	COG0142	geranyltranstransferase activity
OU987_RS10660	COG0776	regulation of translation
OU987_RS10665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OU987_RS10705	COG0539	negative regulation of cytoplasmic translation
OU987_RS10720	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OU987_RS10725	COG2959	enzyme of heme biosynthesis
OU987_RS10730	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS10730	COG3773	Cell wall hydrolase
OU987_RS10735	COG2339	peptidase activity
OU987_RS10740	COG0492	ferredoxin-NADP+ reductase activity
OU987_RS10745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OU987_RS10750	COG4862	establishment of competence for transformation
OU987_RS10755	COG1408	metallophosphoesterase
OU987_RS10765	COG1388	LysM domain
OU987_RS10770	COG1266	CAAX protease self-immunity
OU987_RS10775	COG0514	ATP-dependent DNA helicase (RecQ)
OU987_RS10780	COG4955	Helix-turn-helix domain
OU987_RS10785	COG1141	Ferredoxin
OU987_RS10790	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OU987_RS10795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OU987_RS10805	COG1595	DNA-templated transcription, initiation
OU987_RS10810	COG5002	protein histidine kinase activity
OU987_RS10815	COG0745	RESPONSE REGULATOR receiver
OU987_RS10820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OU987_RS10825	COG1333	cytochrome c biogenesis protein
OU987_RS10830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS10835	COG1187	pseudouridine synthase activity
OU987_RS10840	COG0700	Nucleoside recognition
OU987_RS10845	COG2715	membrane protein required for spore maturation
OU987_RS10850	COG1686	Belongs to the peptidase S11 family
OU987_RS10875	COG1547	Domain of unknown function (DUF309)
OU987_RS10880	COG0456	acetyltransferase
OU987_RS10895	COG0307	riboflavin synthase, alpha
OU987_RS10900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OU987_RS10900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OU987_RS10910	COG0681	Belongs to the peptidase S26 family
OU987_RS10920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OU987_RS10925	COG4086	secreted protein
OU987_RS10930	COG0019	diaminopimelate decarboxylase activity
OU987_RS10935	COG0697	spore germination
OU987_RS10950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU987_RS10970	COG1191	sigma factor activity
OU987_RS10980	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS10985	COG1686	Belongs to the peptidase S11 family
OU987_RS10990	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OU987_RS10995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OU987_RS11000	COG4974	Belongs to the 'phage' integrase family
OU987_RS11010	COG0735	belongs to the Fur family
OU987_RS11015	COG1300	Membrane
OU987_RS11030	COG0281	malic enzyme
OU987_RS11035	COG1757	Na H antiporter
OU987_RS11040	COG1027	Aspartate ammonia-lyase
OU987_RS11045	COG0252	asparaginase activity
OU987_RS11050	COG1396	sequence-specific DNA binding
OU987_RS11055	COG1379	DNA repair
OU987_RS11060	COG0494	nUDIX hydrolase
OU987_RS11070	COG0667	Aldo Keto reductase
OU987_RS11080	COG1073	alpha beta
OU987_RS11090	COG4918	Iron-sulphur cluster biosynthesis
OU987_RS11095	COG0456	acetyltransferase
OU987_RS11095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OU987_RS11100	COG2329	Antibiotic biosynthesis monooxygenase
OU987_RS11105	COG0456	acetyltransferase
OU987_RS11110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OU987_RS11125	COG0628	permease
OU987_RS11135	COG0346	lactoylglutathione lyase activity
OU987_RS11145	COG3048	D-serine ammonia-lyase activity
OU987_RS11150	COG0300	oxidoreductase activity
OU987_RS11155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS11160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OU987_RS11165	COG1024	Enoyl-CoA hydratase
OU987_RS11170	COG3425	synthase
OU987_RS11175	COG2124	cytochrome p450
OU987_RS11180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS11180	COG3321	synthase
OU987_RS11180	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11185	COG3321	synthase
OU987_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS11185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS11185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11190	COG3321	synthase
OU987_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11190	COG0300	oxidoreductase activity
OU987_RS11190	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS11195	COG3321	synthase
OU987_RS11195	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11195	COG0300	oxidoreductase activity
OU987_RS11200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS11200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS11200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11200	COG3321	synthase
OU987_RS11205	COG0300	oxidoreductase activity
OU987_RS11205	COG3321	synthase
OU987_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11205	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS11210	COG3321	synthase
OU987_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS11210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU987_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS11235	COG2070	2-Nitropropane dioxygenase
OU987_RS11235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OU987_RS11240	COG0250	Participates in transcription elongation, termination and antitermination
OU987_RS11260	COG0596	Alpha beta hydrolase
OU987_RS11275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OU987_RS11280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OU987_RS11295	COG0706	membrane insertase activity
OU987_RS11300	COG2195	Cleaves the N-terminal amino acid of tripeptides
OU987_RS11305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OU987_RS11310	COG0346	lactoylglutathione lyase activity
OU987_RS11325	COG4129	membrane
OU987_RS11330	COG1126	abc transporter atp-binding protein
OU987_RS11335	COG0765	amino acid transport
OU987_RS11340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU987_RS11350	COG1597	lipid kinase activity
OU987_RS11355	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU987_RS11360	COG0022	dehydrogenase e1 component
OU987_RS11365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU987_RS11370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU987_RS11375	COG3426	butyrate kinase activity
OU987_RS11380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OU987_RS11385	COG0280	phosphate acetyltransferase
OU987_RS11390	COG3829	transcription factor binding
OU987_RS11390	COG3290	protein histidine kinase activity
OU987_RS11400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OU987_RS11405	COG2079	MmgE PrpD family protein
OU987_RS11410	COG0372	Belongs to the citrate synthase family
OU987_RS11415	COG1960	acyl-CoA dehydrogenase activity
OU987_RS11420	COG1250	3-hydroxyacyl-CoA dehydrogenase
OU987_RS11425	COG0183	Belongs to the thiolase family
OU987_RS11430	COG0584	glycerophosphoryl diester phosphodiesterase
OU987_RS11435	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS11460	COG1902	pentaerythritol trinitrate reductase activity
OU987_RS11475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OU987_RS11480	COG0745	RESPONSE REGULATOR receiver
OU987_RS11485	COG0750	zinc metalloprotease
OU987_RS11490	COG0497	DNA recombination
OU987_RS11500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OU987_RS11510	COG0142	geranyltranstransferase activity
OU987_RS11520	COG1570	exodeoxyribonuclease VII activity
OU987_RS11535	COG1302	Protein conserved in bacteria
OU987_RS11540	COG0439	Biotin carboxylase
OU987_RS11545	COG0511	ligase activity, forming carbon-carbon bonds
OU987_RS11585	COG3854	ATPases associated with a variety of cellular activities
OU987_RS11600	COG0006	proline dipeptidase activity
OU987_RS11610	COG3872	metal-dependent enzyme
OU987_RS11620	COG1752	Esterase of the alpha-beta hydrolase superfamily
OU987_RS11635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU987_RS11655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OU987_RS11670	COG1396	sequence-specific DNA binding
OU987_RS11680	COG0681	Belongs to the peptidase S26 family
OU987_RS11705	COG4940	Competence protein ComGF
OU987_RS11715	COG4970	Tfp pilus assembly protein FimT
OU987_RS11720	COG4537	Required for transformation and DNA binding
OU987_RS11725	COG1459	type II secretion system
OU987_RS11730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OU987_RS11735	COG0598	Magnesium transport protein CorA
OU987_RS11740	COG1253	flavin adenine dinucleotide binding
OU987_RS11745	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS11755	COG1393	Belongs to the ArsC family
OU987_RS11765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS11775	COG0011	TIGRFAM Protein of
OU987_RS11785	COG2866	Carboxypeptidase
OU987_RS11790	COG1940	carbohydrate kinase activity
OU987_RS11795	COG4483	Protein conserved in bacteria
OU987_RS11800	COG1757	Na H antiporter
OU987_RS11810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OU987_RS11825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OU987_RS11830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OU987_RS11835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OU987_RS11840	COG0581	inorganic phosphate transmembrane transporter activity
OU987_RS11845	COG0573	inorganic phosphate transmembrane transporter activity
OU987_RS11850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OU987_RS11855	COG0768	penicillin binding
OU987_RS11860	COG0477	Major facilitator Superfamily
OU987_RS11865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OU987_RS11870	COG2839	Protein conserved in bacteria
OU987_RS11875	COG5521	maltodextrose utilization protein MalA
OU987_RS11880	COG1388	LysM domain
OU987_RS11890	COG4709	membrane
OU987_RS11895	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OU987_RS11900	COG0735	belongs to the Fur family
OU987_RS11905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS11920	COG0513	Belongs to the DEAD box helicase family
OU987_RS11935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OU987_RS11940	COG2384	SAM-dependent methyltransferase
OU987_RS11945	COG2010	Cytochrome c
OU987_RS11950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OU987_RS11955	COG0358	DNA primase activity
OU987_RS11970	COG0517	IMP dehydrogenase activity
OU987_RS11975	COG0751	glycine-tRNA ligase activity
OU987_RS11995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OU987_RS12000	COG0295	cytidine deaminase activity
OU987_RS12005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OU987_RS12015	COG1480	7TM receptor with intracellular HD hydrolase
OU987_RS12020	COG1702	phosphate starvation-inducible protein PhoH
OU987_RS12025	COG0561	phosphatase activity
OU987_RS12040	COG4864	UPF0365 protein
OU987_RS12045	COG1030	water channel activity
OU987_RS12050	COG1610	YqeY-like protein
OU987_RS12060	COG1283	sodium-dependent phosphate transmembrane transporter activity
OU987_RS12065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OU987_RS12070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OU987_RS12100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OU987_RS12115	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS12145	COG0658	competence protein
OU987_RS12145	COG2333	competence protein COMEC
OU987_RS12150	COG2131	deaminase
OU987_RS12155	COG1596	polysaccharide export
OU987_RS12155	COG1555	photosystem II stabilization
OU987_RS12160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OU987_RS12165	COG2226	methyltransferase
OU987_RS12170	COG0799	negative regulation of ribosome biogenesis
OU987_RS12175	COG1713	HD superfamily hydrolase involved in NAD metabolism
OU987_RS12185	COG1534	Rna-binding protein
OU987_RS12190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OU987_RS12195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OU987_RS12200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OU987_RS12215	COG2755	lipolytic protein G-D-S-L family
OU987_RS12225	COG0398	Pfam SNARE associated Golgi protein
OU987_RS12250	COG1794	racemase activity, acting on amino acids and derivatives
OU987_RS12270	COG0656	L-ascorbic acid biosynthetic process
OU987_RS12300	COG3677	Transposase
OU987_RS12340	COG0642	Histidine kinase
OU987_RS12340	COG5002	protein histidine kinase activity
OU987_RS12345	COG0745	RESPONSE REGULATOR receiver
OU987_RS12350	COG2311	Membrane
OU987_RS12360	COG0454	-acetyltransferase
OU987_RS12365	COG0563	adenylate kinase activity
OU987_RS12375	COG2814	Major facilitator Superfamily
OU987_RS12380	COG0456	acetyltransferase
OU987_RS12385	COG2318	DinB family
OU987_RS12395	COG0561	phosphatase activity
OU987_RS12400	COG0561	phosphatase activity
OU987_RS12410	COG1482	cell wall glycoprotein biosynthetic process
OU987_RS12415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS12415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU987_RS12415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU987_RS12420	COG3711	transcriptional antiterminator
OU987_RS12420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS12430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OU987_RS12435	COG0583	DNA-binding transcription factor activity
OU987_RS12440	COG2814	Major facilitator Superfamily
OU987_RS12445	COG2124	cytochrome p450
OU987_RS12445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OU987_RS12450	COG1309	transcriptional regulator
OU987_RS12455	COG2226	methyltransferase
OU987_RS12470	COG2116	formate transmembrane transporter activity
OU987_RS12475	COG5609	conserved protein (DUF2294)
OU987_RS12480	COG3383	formate dehydrogenase (NAD+) activity
OU987_RS12485	COG2427	Protein of unknown function (DUF1641)
OU987_RS12495	COG0626	cystathionine gamma-synthase activity
OU987_RS12500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU987_RS12525	COG0768	penicillin binding
OU987_RS12540	COG0826	peptidase U32
OU987_RS12545	COG0826	peptidase U32
OU987_RS12550	COG4122	O-methyltransferase activity
OU987_RS12555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OU987_RS12580	COG0628	permease
OU987_RS12585	COG1126	abc transporter atp-binding protein
OU987_RS12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU987_RS12595	COG0765	amino acid transport
OU987_RS12600	COG0765	amino acid transport
OU987_RS12615	COG3881	PFAM PRC-barrel domain
OU987_RS12620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OU987_RS12625	COG0457	Tetratricopeptide repeat
OU987_RS12635	COG1104	cysteine desulfurase activity
OU987_RS12640	COG1959	2 iron, 2 sulfur cluster binding
OU987_RS12645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OU987_RS12650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OU987_RS12675	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS12675	COG3103	Sh3 type 3 domain protein
OU987_RS12675	COG4991	sh3 domain protein
OU987_RS12685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OU987_RS12695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OU987_RS12695	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OU987_RS12700	COG5416	Lipopolysaccharide assembly protein A domain
OU987_RS12705	COG0490	domain, Protein
OU987_RS12710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OU987_RS12710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OU987_RS12720	COG2244	polysaccharide biosynthetic process
OU987_RS12725	COG2323	membrane
OU987_RS12735	COG1862	Preprotein translocase
OU987_RS12775	COG1388	LysM domain
OU987_RS12785	COG0157	Belongs to the NadC ModD family
OU987_RS12790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OU987_RS12795	COG1104	cysteine desulfurase activity
OU987_RS12800	COG1827	regulation of RNA biosynthetic process
OU987_RS12805	COG0077	Prephenate dehydratase
OU987_RS12820	COG3290	protein histidine kinase activity
OU987_RS12825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OU987_RS12830	COG2868	ribosomal protein
OU987_RS12840	COG1994	Peptidase M50
OU987_RS12845	COG0739	heme binding
OU987_RS12850	COG2894	cell division
OU987_RS12855	COG0850	regulation of cytokinetic process
OU987_RS12860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OU987_RS12870	COG1077	Cell shape determining protein MreB Mrl
OU987_RS12890	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OU987_RS12895	COG0285	dihydrofolate synthase activity
OU987_RS12900	COG0525	valine-tRNA ligase activity
OU987_RS12910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OU987_RS12915	COG1388	LysM domain
OU987_RS12925	COG0113	porphobilinogen synthase activity
OU987_RS12930	COG1587	Uroporphyrinogen-III synthase
OU987_RS12940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OU987_RS12960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OU987_RS12965	COG0470	DNA polymerase III
OU987_RS12965	COG1067	ATP-dependent peptidase activity
OU987_RS12980	COG0457	Tetratricopeptide repeat
OU987_RS12980	COG1477	protein flavinylation
OU987_RS12995	COG0473	3-isopropylmalate dehydrogenase activity
OU987_RS13010	COG0440	acetolactate synthase activity
OU987_RS13015	COG0028	Belongs to the TPP enzyme family
OU987_RS13040	COG0622	Phosphoesterase
OU987_RS13045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OU987_RS13055	COG5401	PFAM Sporulation and spore germination
OU987_RS13065	COG1846	Transcriptional regulator
OU987_RS13070	COG2197	response regulator
OU987_RS13075	COG0824	Thioesterase
OU987_RS13080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OU987_RS13085	COG1053	succinate dehydrogenase
OU987_RS13090	COG2009	succinate dehydrogenase
OU987_RS13095	COG1719	4-vinyl reductase, 4VR
OU987_RS13100	COG0527	aspartate kinase activity
OU987_RS13110	COG3118	belongs to the thioredoxin family
OU987_RS13115	COG3534	alpha-L-arabinofuranosidase
OU987_RS13120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OU987_RS13125	COG2086	electron transfer activity
OU987_RS13130	COG1024	Enoyl-CoA hydratase
OU987_RS13135	COG1309	transcriptional regulator
OU987_RS13140	COG0318	PFAM AMP-dependent synthetase and ligase
OU987_RS13150	COG3766	membrane
OU987_RS13160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OU987_RS13160	COG1796	DNA polymerase
OU987_RS13165	COG1286	toxin biosynthetic process
OU987_RS13180	COG0072	phenylalanine-tRNA ligase activity
OU987_RS13180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU987_RS13185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OU987_RS13190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OU987_RS13200	COG3835	regulator
OU987_RS13205	COG0277	FAD linked oxidase domain protein
OU987_RS13210	COG0247	lactate metabolic process
OU987_RS13215	COG1966	Carbon starvation protein
OU987_RS13220	COG3534	alpha-L-arabinofuranosidase
OU987_RS13225	COG0395	ABC-type sugar transport system, permease component
OU987_RS13230	COG1175	transmembrane transport
OU987_RS13235	COG1653	transport
OU987_RS13245	COG0647	UMP catabolic process
OU987_RS13250	COG0235	Class ii aldolase
OU987_RS13255	COG1069	ribulokinase activity
OU987_RS13260	COG2160	L-arabinose isomerase activity
OU987_RS13265	COG3507	Belongs to the glycosyl hydrolase 43 family
OU987_RS13270	COG1363	Peptidase, m42
OU987_RS13280	COG3326	Membrane
OU987_RS13295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OU987_RS13300	COG1346	cytolysis
OU987_RS13305	COG1380	Effector of murein hydrolase LrgA
OU987_RS13310	COG3279	Response regulator of the LytR AlgR family
OU987_RS13315	COG3275	phosphorelay sensor kinase activity
OU987_RS13320	COG1011	Hydrolase
OU987_RS13335	COG0398	Pfam SNARE associated Golgi protein
OU987_RS13340	COG1484	DNA-dependent DNA replication
OU987_RS13345	COG3611	Membrane attachment protein
OU987_RS13360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OU987_RS13365	COG1733	regulation of RNA biosynthetic process
OU987_RS13370	COG2814	Major facilitator Superfamily
OU987_RS13375	COG0656	L-ascorbic acid biosynthetic process
OU987_RS13380	COG0237	dephospho-CoA kinase activity
OU987_RS13385	COG1971	Probably functions as a manganese efflux pump
OU987_RS13390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OU987_RS13395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU987_RS13395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU987_RS13400	COG5002	protein histidine kinase activity
OU987_RS13405	COG0745	RESPONSE REGULATOR receiver
OU987_RS13415	COG0538	isocitrate dehydrogenase activity
OU987_RS13420	COG0372	Belongs to the citrate synthase family
OU987_RS13450	COG0628	permease
OU987_RS13455	COG3030	protein affecting phage T7 exclusion by the F plasmid
OU987_RS13460	COG0469	pyruvate kinase activity
OU987_RS13480	COG0281	malic enzyme
OU987_RS13485	COG0587	DNA-directed DNA polymerase activity
OU987_RS13505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OU987_RS13515	COG4109	DRTGG domain
OU987_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS13545	COG0521	Mo-molybdopterin cofactor biosynthetic process
OU987_RS13555	COG0827	DNA restriction-modification system
OU987_RS13560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OU987_RS13565	COG3874	Sporulation protein YtfJ
OU987_RS13575	COG1714	RDD family
OU987_RS13580	COG0616	signal peptide processing
OU987_RS13585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OU987_RS13590	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OU987_RS13595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OU987_RS13610	COG1104	cysteine desulfurase activity
OU987_RS13615	COG1114	Component of the transport system for branched-chain amino acids
OU987_RS13625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OU987_RS13630	COG1309	transcriptional regulator
OU987_RS13635	COG1956	GAF domain-containing protein
OU987_RS13640	COG2203	Gaf domain
OU987_RS13640	COG2199	diguanylate cyclase activity
OU987_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS13655	COG4282	regulation of fungal-type cell wall biogenesis
OU987_RS13700	COG1017	nitric oxide dioxygenase activity
OU987_RS13700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OU987_RS13710	COG0693	protein deglycase activity
OU987_RS13730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OU987_RS13735	COG1378	Sugar-specific transcriptional regulator TrmB
OU987_RS13760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OU987_RS13765	COG0454	-acetyltransferase
OU987_RS13770	COG0517	IMP dehydrogenase activity
OU987_RS13775	COG0123	including yeast histone deacetylase and acetoin utilization protein
OU987_RS13780	COG1360	Flagellar Motor Protein
OU987_RS13785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OU987_RS13790	COG1609	Transcriptional regulator
OU987_RS13795	COG1605	Chorismate mutase
OU987_RS13795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OU987_RS13800	COG3118	belongs to the thioredoxin family
OU987_RS13805	COG4980	gas vesicle protein
OU987_RS13810	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OU987_RS13820	COG1674	ftsk spoiiie
OU987_RS13825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU987_RS13835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS13845	COG1363	Peptidase, m42
OU987_RS13850	COG5584	Small secreted protein
OU987_RS13855	COG0281	malic enzyme
OU987_RS13860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU987_RS13875	COG0510	thiamine kinase activity
OU987_RS13880	COG1597	lipid kinase activity
OU987_RS13890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OU987_RS13895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU987_RS13900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU987_RS13905	COG2252	PERMEase
OU987_RS13910	COG4473	ABC transporter
OU987_RS13915	COG1131	(ABC) transporter
OU987_RS13920	COG1349	DNA-binding transcription factor activity
OU987_RS13925	COG1187	pseudouridine synthase activity
OU987_RS13930	COG2244	polysaccharide biosynthetic process
OU987_RS13935	COG2081	HI0933 family
OU987_RS13940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OU987_RS13950	COG1609	Transcriptional regulator
OU987_RS13955	COG1653	transport
OU987_RS13960	COG1175	transmembrane transport
OU987_RS13965	COG0395	ABC-type sugar transport system, permease component
OU987_RS13970	COG1486	melibiose metabolic process
OU987_RS13980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU987_RS13995	COG2202	Pas domain
OU987_RS13995	COG1366	Belongs to the anti-sigma-factor antagonist family
OU987_RS14000	COG2814	Major facilitator Superfamily
OU987_RS14005	COG5522	Integral membrane protein (intg_mem_TP0381)
OU987_RS14010	COG0577	efflux transmembrane transporter activity
OU987_RS14015	COG1136	(ABC) transporter
OU987_RS14020	COG2205	protein histidine kinase activity
OU987_RS14025	COG0745	RESPONSE REGULATOR receiver
OU987_RS14030	COG0577	efflux transmembrane transporter activity
OU987_RS14035	COG1136	(ABC) transporter
OU987_RS14055	COG1131	(ABC) transporter
OU987_RS14060	COG1725	Transcriptional regulator
OU987_RS14075	COG1242	4 iron, 4 sulfur cluster binding
OU987_RS14080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OU987_RS14090	COG0584	glycerophosphoryl diester phosphodiesterase
OU987_RS14100	COG2267	carboxylic ester hydrolase activity
OU987_RS14105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OU987_RS14110	COG1113	amino acid transport
OU987_RS14115	COG0367	asparagine synthase
OU987_RS14135	COG1506	peptidase
OU987_RS14140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OU987_RS14145	COG1116	anion transmembrane transporter activity
OU987_RS14150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OU987_RS14155	COG0494	nUDIX hydrolase
OU987_RS14160	COG4824	toxin secretion phage lysis holin
OU987_RS14165	COG0783	Belongs to the Dps family
OU987_RS14190	COG0288	reversible hydration of carbon dioxide
OU987_RS14200	COG1271	oxidase subunit
OU987_RS14205	COG1294	oxidase, subunit
OU987_RS14220	COG4948	Mandelate Racemase Muconate Lactonizing
OU987_RS14230	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OU987_RS14235	COG0596	Alpha beta hydrolase
OU987_RS14245	COG1169	isochorismate synthase
OU987_RS14250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU987_RS14255	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OU987_RS14380	COG3859	Proton-coupled thiamine transporter YuaJ
OU987_RS14385	COG2268	Band 7 protein
OU987_RS14390	COG1585	Membrane protein implicated in regulation of membrane protease activity
OU987_RS14395	COG2318	DinB family
OU987_RS14405	COG1454	alcohol dehydrogenase
OU987_RS14410	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS14415	COG1510	regulation of RNA biosynthetic process
OU987_RS14425	COG0569	domain protein
OU987_RS14430	COG1705	Flagellar rod assembly protein muramidase FlgJ
OU987_RS14435	COG1017	nitric oxide dioxygenase activity
OU987_RS14435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OU987_RS14460	COG0628	permease
OU987_RS14465	COG0673	inositol 2-dehydrogenase activity
OU987_RS14470	COG0693	protein deglycase activity
OU987_RS14475	COG0840	transmembrane signaling receptor activity
OU987_RS14480	COG0840	transmembrane signaling receptor activity
OU987_RS14485	COG0840	transmembrane signaling receptor activity
OU987_RS14490	COG0840	transmembrane signaling receptor activity
OU987_RS14505	COG2070	2-Nitropropane dioxygenase
OU987_RS14510	COG0432	Pfam Uncharacterised protein family UPF0047
OU987_RS14515	COG0366	Alpha amylase catalytic
OU987_RS14520	COG1253	flavin adenine dinucleotide binding
OU987_RS14525	COG2738	Putative neutral zinc metallopeptidase
OU987_RS14540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OU987_RS14565	COG1335	isochorismatase
OU987_RS14570	COG1979	alcohol dehydrogenase
OU987_RS14575	COG1979	alcohol dehydrogenase
OU987_RS14580	COG2155	Conserved Protein
OU987_RS14585	COG1098	S1 RNA binding domain
OU987_RS14590	COG0436	Aminotransferase
OU987_RS14595	COG1522	sequence-specific DNA binding
OU987_RS14600	COG2267	carboxylic ester hydrolase activity
OU987_RS14610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OU987_RS14615	COG2205	protein histidine kinase activity
OU987_RS14625	COG5018	Exonuclease
OU987_RS14630	COG2814	Major facilitator Superfamily
OU987_RS14635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU987_RS14640	COG3011	Protein conserved in bacteria
OU987_RS14650	COG3290	protein histidine kinase activity
OU987_RS14655	COG4565	transcriptional regulatory protein
OU987_RS14660	COG1744	ABC transporter substrate-binding protein PnrA-like
OU987_RS14665	COG3845	ABC transporter
OU987_RS14670	COG4603	Belongs to the binding-protein-dependent transport system permease family
OU987_RS14675	COG1079	Belongs to the binding-protein-dependent transport system permease family
OU987_RS14685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OU987_RS14685	COG2111	Na H antiporter
OU987_RS14690	COG2111	Na H antiporter
OU987_RS14695	COG1006	Multisubunit Na H antiporter MnhC subunit
OU987_RS14700	COG0651	ATP synthesis coupled electron transport
OU987_RS14705	COG1863	multisubunit Na H antiporter MnhE subunit
OU987_RS14710	COG2212	antiporter activity
OU987_RS14715	COG1320	monovalent cation:proton antiporter activity
OU987_RS14720	COG2050	protein possibly involved in aromatic compounds catabolism
OU987_RS14725	COG2197	response regulator
OU987_RS14730	COG4585	Histidine kinase
OU987_RS14755	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OU987_RS14760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OU987_RS14765	COG1335	isochorismatase
OU987_RS14770	COG5506	Protein of unknown function (DUF1694)
OU987_RS14785	COG0628	permease
OU987_RS14795	COG1418	mRNA catabolic process
OU987_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS14810	COG1511	domain protein
OU987_RS14815	COG1674	ftsk spoiiie
OU987_RS14815	COG0433	COG0433 Predicted ATPase
OU987_RS14820	COG4499	WXG100 protein secretion system (Wss), protein YukC
OU987_RS14825	COG5417	Belongs to the EsaB family
OU987_RS14830	COG4842	Belongs to the WXG100 family
OU987_RS14835	COG2508	Transcriptional regulator
OU987_RS14835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OU987_RS14840	COG0686	Belongs to the AlaDH PNT family
OU987_RS14845	COG5634	Uncharacterized conserved protein (DUF2278)
OU987_RS14850	COG3251	PFAM MbtH domain protein
OU987_RS14855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU987_RS14860	COG1535	isochorismatase
OU987_RS14860	COG3433	isochorismatase activity
OU987_RS14865	COG1021	2,3-dihydroxybenzoate-AMP ligase
OU987_RS14870	COG1169	isochorismate synthase
OU987_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS14880	COG2819	hydrolase of the alpha beta superfamily
OU987_RS14885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OU987_RS14890	COG1268	BioY protein
OU987_RS14895	COG2056	Na+-H+ antiporter family
OU987_RS14905	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OU987_RS14910	COG3584	3D domain protein
OU987_RS14925	COG1252	NADH dehydrogenase
OU987_RS14955	COG1131	(ABC) transporter
OU987_RS14975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU987_RS14980	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OU987_RS14985	COG0316	Belongs to the HesB IscA family
OU987_RS14995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU987_RS15005	COG1252	NADH dehydrogenase
OU987_RS15010	COG4837	Protein of unknown function (DUF1462)
OU987_RS15015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OU987_RS15020	COG0823	Involved in the tonB-independent uptake of proteins
OU987_RS15020	COG1506	peptidase
OU987_RS15020	COG4946	Tricorn protease homolog
OU987_RS15030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OU987_RS15035	COG0460	homoserine dehydrogenase
OU987_RS15040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OU987_RS15045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OU987_RS15050	COG0647	UMP catabolic process
OU987_RS15055	COG2445	Protein of unknown function DUF86
OU987_RS15060	COG4470	Protein conserved in bacteria
OU987_RS15070	COG0739	heme binding
OU987_RS15080	COG0737	Belongs to the 5'-nucleotidase family
OU987_RS15085	COG0730	response to heat
OU987_RS15090	COG1801	Protein of unknown function DUF72
OU987_RS15105	COG2508	Transcriptional regulator
OU987_RS15130	COG2814	Major facilitator Superfamily
OU987_RS15135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OU987_RS15140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU987_RS15145	COG2356	endonuclease I
OU987_RS15150	COG3842	ATPase activity
OU987_RS15155	COG2188	Transcriptional regulator
OU987_RS15160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU987_RS15165	COG0395	ABC-type sugar transport system, permease component
OU987_RS15170	COG1175	transmembrane transport
OU987_RS15175	COG1653	transport
OU987_RS15180	COG2222	sugar isomerase
OU987_RS15185	COG0789	Transcriptional regulator
OU987_RS15210	COG0322	excinuclease ABC activity
OU987_RS15215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OU987_RS15235	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS15240	COG0719	Fe-S assembly protein
OU987_RS15245	COG0822	iron-sulfur transferase activity
OU987_RS15250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OU987_RS15255	COG0719	Fe-S assembly protein
OU987_RS15260	COG0396	ATPase activity
OU987_RS15270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OU987_RS15275	COG1464	Belongs to the NlpA lipoprotein family
OU987_RS15280	COG2011	ABC-type metal ion transport system permease component
OU987_RS15285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OU987_RS15295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU987_RS15300	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OU987_RS15315	COG1393	Belongs to the ArsC family
OU987_RS15320	COG1960	acyl-CoA dehydrogenase activity
OU987_RS15325	COG0183	Belongs to the thiolase family
OU987_RS15330	COG1024	Enoyl-CoA hydratase
OU987_RS15330	COG1250	3-hydroxyacyl-CoA dehydrogenase
OU987_RS15350	COG5577	PFAM Coat F domain
OU987_RS15355	COG1846	Transcriptional regulator
OU987_RS15360	COG0477	Major facilitator Superfamily
OU987_RS15365	COG1942	4-Oxalocrotonate Tautomerase
OU987_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS15375	COG0583	DNA-binding transcription factor activity
OU987_RS15385	COG0583	DNA-binding transcription factor activity
OU987_RS15405	COG1120	ATPase activity
OU987_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS15425	COG0783	Belongs to the Dps family
OU987_RS15430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU987_RS15435	COG0745	RESPONSE REGULATOR receiver
OU987_RS15440	COG2205	protein histidine kinase activity
OU987_RS15440	COG2770	Histidine kinase
OU987_RS15450	COG1309	transcriptional regulator
OU987_RS15455	COG0114	fumarate hydratase activity
OU987_RS15465	COG0697	spore germination
OU987_RS15470	COG0814	amino acid
OU987_RS15480	COG2197	response regulator
OU987_RS15485	COG4585	Histidine kinase
OU987_RS15490	COG4758	membrane
OU987_RS15495	COG3595	metallopeptidase activity
OU987_RS15500	COG1842	Phage shock protein A
OU987_RS15505	COG4758	membrane
OU987_RS15510	COG2814	Major facilitator Superfamily
OU987_RS15515	COG2096	Adenosyltransferase
OU987_RS15520	COG1120	ATPase activity
OU987_RS15525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS15530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU987_RS15535	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS15540	COG3386	PFAM SMP-30 Gluconolaconase
OU987_RS15545	COG2205	protein histidine kinase activity
OU987_RS15550	COG0745	RESPONSE REGULATOR receiver
OU987_RS15560	COG1191	sigma factor activity
OU987_RS15570	COG2140	Oxalate decarboxylase
OU987_RS15580	COG1120	ATPase activity
OU987_RS15585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS15590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS15595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU987_RS15600	COG0531	amino acid
OU987_RS15610	COG1988	membrane-bound metal-dependent
OU987_RS15615	COG1368	sulfuric ester hydrolase activity
OU987_RS15620	COG1910	domain protein
OU987_RS15625	COG0725	ABC transporter, periplasmic molybdate-binding protein
OU987_RS15630	COG4149	molybdate abc transporter
OU987_RS15635	COG2197	response regulator
OU987_RS15640	COG3850	Histidine kinase
OU987_RS15645	COG1131	(ABC) transporter
OU987_RS15655	COG0842	Transport permease protein
OU987_RS15660	COG0656	L-ascorbic acid biosynthetic process
OU987_RS15680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OU987_RS15685	COG3973	AAA domain
OU987_RS15690	COG2860	membrane
OU987_RS15700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OU987_RS15705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OU987_RS15710	COG2217	Heavy metal translocating P-type atpase
OU987_RS15715	COG2217	Heavy metal translocating P-type atpase
OU987_RS15720	COG2608	mercury ion transmembrane transporter activity
OU987_RS15725	COG1937	Protein conserved in bacteria
OU987_RS15730	COG0673	inositol 2-dehydrogenase activity
OU987_RS15740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS15745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OU987_RS15750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS15755	COG1126	abc transporter atp-binding protein
OU987_RS15760	COG0765	amino acid transport
OU987_RS15765	COG0765	amino acid transport
OU987_RS15770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU987_RS15775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU987_RS15780	COG0454	-acetyltransferase
OU987_RS15785	COG0583	DNA-binding transcription factor activity
OU987_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS15835	COG0557	exoribonuclease II activity
OU987_RS15840	COG1647	Serine aminopeptidase, S33
OU987_RS15845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OU987_RS15850	COG1476	TRANSCRIPTIONal
OU987_RS15855	COG1396	sequence-specific DNA binding
OU987_RS15860	COG1396	sequence-specific DNA binding
OU987_RS15865	COG1733	regulation of RNA biosynthetic process
OU987_RS15890	COG1131	(ABC) transporter
OU987_RS15895	COG1174	glycine betaine transport
OU987_RS15900	COG1732	Glycine betaine
OU987_RS15905	COG1174	glycine betaine transport
OU987_RS15910	COG0517	IMP dehydrogenase activity
OU987_RS15910	COG1125	glycine betaine transport
OU987_RS15915	COG1510	regulation of RNA biosynthetic process
OU987_RS15920	COG1174	glycine betaine transport
OU987_RS15925	COG1732	Glycine betaine
OU987_RS15930	COG1174	glycine betaine transport
OU987_RS15935	COG0517	IMP dehydrogenase activity
OU987_RS15935	COG1125	glycine betaine transport
OU987_RS15940	COG1510	regulation of RNA biosynthetic process
OU987_RS15945	COG2095	MarC family integral membrane protein
OU987_RS15950	COG3064	Membrane
OU987_RS15955	COG4640	response to antibiotic
OU987_RS15960	COG0456	acetyltransferase
OU987_RS15975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU987_RS15995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU987_RS16000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU987_RS16010	COG2234	aminopeptidase activity
OU987_RS16030	COG0126	phosphoglycerate kinase activity
OU987_RS16035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OU987_RS16040	COG2390	Transcriptional regulator
OU987_RS16045	COG2814	Major facilitator Superfamily
OU987_RS16050	COG1609	Transcriptional regulator
OU987_RS16055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS16065	COG0583	DNA-binding transcription factor activity
OU987_RS16070	COG0697	spore germination
OU987_RS16075	COG1113	amino acid transport
OU987_RS16080	COG1609	Transcriptional regulator
OU987_RS16090	COG0561	phosphatase activity
OU987_RS16095	COG1737	Transcriptional regulator
OU987_RS16100	COG1070	Carbohydrate kinase
OU987_RS16140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS16145	COG2186	Transcriptional regulator
OU987_RS16150	COG1620	l-lactate permease
OU987_RS16155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OU987_RS16165	COG5039	Polysaccharide pyruvyl transferase
OU987_RS16170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU987_RS16175	COG0110	maltose O-acetyltransferase activity
OU987_RS16180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OU987_RS16185	COG2244	polysaccharide biosynthetic process
OU987_RS16190	COG1216	Glycosyl transferase, family 2
OU987_RS16195	COG5039	Polysaccharide pyruvyl transferase
OU987_RS16200	COG1216	Glycosyl transferase, family 2
OU987_RS16210	COG0438	transferase activity, transferring glycosyl groups
OU987_RS16215	COG1215	transferase activity, transferring glycosyl groups
OU987_RS16220	COG0438	transferase activity, transferring glycosyl groups
OU987_RS16225	COG1086	Polysaccharide biosynthesis protein
OU987_RS16230	COG0489	protein tyrosine kinase activity
OU987_RS16235	COG3944	biosynthesis protein
OU987_RS16240	COG1396	sequence-specific DNA binding
OU987_RS16245	COG2272	Belongs to the type-B carboxylesterase lipase family
OU987_RS16250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OU987_RS16255	COG2364	Membrane
OU987_RS16260	COG0456	acetyltransferase
OU987_RS16265	COG3479	Phenolic acid decarboxylase
OU987_RS16320	COG2223	nitrite transmembrane transporter activity
OU987_RS16325	COG1609	Transcriptional regulator
OU987_RS16335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OU987_RS16340	COG0366	Alpha amylase catalytic
OU987_RS16345	COG1554	hydrolase, family 65, central catalytic
OU987_RS16350	COG5521	maltodextrose utilization protein MalA
OU987_RS16355	COG3833	ABC-type maltose transport systems, permease component
OU987_RS16360	COG1175	transmembrane transport
OU987_RS16365	COG2182	Extracellular solute-binding protein
OU987_RS16370	COG0366	Alpha amylase catalytic
OU987_RS16375	COG1609	Transcriptional regulator
OU987_RS16380	COG1611	Belongs to the LOG family
OU987_RS16385	COG1694	Mazg nucleotide pyrophosphohydrolase
OU987_RS16390	COG0659	secondary active sulfate transmembrane transporter activity
OU987_RS16395	COG0288	reversible hydration of carbon dioxide
OU987_RS16400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU987_RS16405	COG4290	ribonuclease
OU987_RS16410	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OU987_RS16415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS16425	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OU987_RS16435	COG1051	belongs to the nudix hydrolase family
OU987_RS16440	COG0492	ferredoxin-NADP+ reductase activity
OU987_RS16445	COG0791	NLP P60 protein
OU987_RS16445	COG3883	PFAM NLP P60 protein
OU987_RS16450	COG0457	Tetratricopeptide repeat
OU987_RS16455	COG5002	protein histidine kinase activity
OU987_RS16460	COG0745	RESPONSE REGULATOR receiver
OU987_RS16465	COG1132	(ABC) transporter
OU987_RS16470	COG0140	phosphoribosyl-ATP diphosphatase activity
OU987_RS16470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OU987_RS16495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OU987_RS16510	COG4990	cell redox homeostasis
OU987_RS16515	COG0110	maltose O-acetyltransferase activity
OU987_RS16535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OU987_RS16545	COG2188	Transcriptional regulator
OU987_RS16550	COG1309	transcriptional regulator
OU987_RS16555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OU987_RS16560	COG1950	PFAM Membrane protein of
OU987_RS16565	COG1983	PspC domain protein
OU987_RS16570	COG3595	metallopeptidase activity
OU987_RS16585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OU987_RS16595	COG4897	Protein conserved in bacteria
OU987_RS16600	COG3848	Pyruvate phosphate dikinase
OU987_RS16600	COG0574	Belongs to the PEP-utilizing enzyme family
OU987_RS16605	COG1309	transcriptional regulator
OU987_RS16610	COG2814	Major facilitator Superfamily
OU987_RS16625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU987_RS16635	COG0793	Belongs to the peptidase S41A family
OU987_RS16635	COG3409	Peptidoglycan-binding domain 1 protein
OU987_RS16640	COG3420	alginic acid biosynthetic process
OU987_RS16645	COG2177	Part of the ABC transporter FtsEX involved in
OU987_RS16650	COG2884	Cell division ATP-binding protein ftsE
OU987_RS16655	COG2010	Cytochrome c
OU987_RS16660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS16675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OU987_RS16690	COG1516	flagellar protein fliS
OU987_RS16695	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OU987_RS16700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OU987_RS16720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OU987_RS16725	COG1256	bacterial-type flagellum assembly
OU987_RS16725	COG4786	Flagellar basal body rod
OU987_RS16730	COG3418	PFAM FlgN family protein
OU987_RS16735	COG2747	anti-sigma28 factor FlgM
OU987_RS16745	COG1040	competence protein
OU987_RS16755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OU987_RS16760	COG1307	EDD domain protein, DegV family
OU987_RS16765	COG2197	response regulator
OU987_RS16770	COG4585	Histidine kinase
OU987_RS16775	COG1739	Uncharacterized protein family UPF0029
OU987_RS16780	COG1316	TRANSCRIPTIONal
OU987_RS16785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OU987_RS16790	COG0438	transferase activity, transferring glycosyl groups
OU987_RS16795	COG1215	transferase activity, transferring glycosyl groups
OU987_RS16800	COG3206	protein involved in exopolysaccharide biosynthesis
OU987_RS16805	COG3307	-O-antigen
OU987_RS16810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OU987_RS16815	COG0438	transferase activity, transferring glycosyl groups
OU987_RS16815	COG0297	glycogen (starch) synthase activity
OU987_RS16820	COG2244	polysaccharide biosynthetic process
OU987_RS16830	COG2247	cell wall binding repeat
OU987_RS16830	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU987_RS16835	COG2247	cell wall binding repeat
OU987_RS16835	COG2385	sporulation resulting in formation of a cellular spore
OU987_RS16845	COG1316	TRANSCRIPTIONal
OU987_RS16850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OU987_RS16855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OU987_RS16860	COG1134	teichoic acid transport
OU987_RS16865	COG1682	transport, permease protein
OU987_RS16870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU987_RS16880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OU987_RS16885	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OU987_RS16890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU987_RS16895	COG4193	domain, Protein
OU987_RS16900	COG1482	cell wall glycoprotein biosynthetic process
OU987_RS16905	COG0697	spore germination
OU987_RS16910	COG0814	amino acid
OU987_RS16920	COG1215	transferase activity, transferring glycosyl groups
OU987_RS16925	COG2814	Major facilitator Superfamily
OU987_RS16930	COG1316	TRANSCRIPTIONal
OU987_RS16935	COG0561	phosphatase activity
OU987_RS16940	COG2433	Pfam Transposase IS66
OU987_RS16945	COG0791	NLP P60 protein
OU987_RS16955	COG2843	Capsule synthesis protein
OU987_RS16965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OU987_RS16970	COG0697	spore germination
OU987_RS16975	COG0814	amino acid
OU987_RS16985	COG1609	Transcriptional regulator
OU987_RS16990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU987_RS17000	COG1129	ABC transporter
OU987_RS17005	COG1172	Belongs to the binding-protein-dependent transport system permease family
OU987_RS17010	COG1879	ABC-type sugar transport system periplasmic component
OU987_RS17015	COG3103	Sh3 type 3 domain protein
OU987_RS17020	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU987_RS17025	COG3527	Alpha-acetolactate decarboxylase
OU987_RS17030	COG0028	Belongs to the TPP enzyme family
OU987_RS17035	COG0583	DNA-binding transcription factor activity
OU987_RS17040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OU987_RS17055	COG5337	Spore coat protein CotH
OU987_RS17065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OU987_RS17075	COG0405	Gamma-glutamyltransferase
OU987_RS17080	COG1522	sequence-specific DNA binding
OU987_RS17085	COG2059	Chromate
OU987_RS17090	COG2059	Chromate
OU987_RS17100	COG0655	NAD(P)H dehydrogenase (quinone) activity
OU987_RS17105	COG0583	DNA-binding transcription factor activity
OU987_RS17135	COG5444	nuclease activity
OU987_RS17150	COG3878	Protein conserved in bacteria
OU987_RS17155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OU987_RS17160	COG4464	protein tyrosine phosphatase activity
OU987_RS17165	COG0489	protein tyrosine kinase activity
OU987_RS17170	COG3944	biosynthesis protein
OU987_RS17180	COG4715	Zinc finger, swim domain protein
OU987_RS17185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OU987_RS17190	COG0561	phosphatase activity
OU987_RS17195	COG1349	DNA-binding transcription factor activity
OU987_RS17200	COG0629	single-stranded DNA binding
OU987_RS17225	COG0457	Tetratricopeptide repeat
OU987_RS17230	COG4786	Flagellar basal body rod
OU987_RS17235	COG4786	Flagellar basal body rod
OU987_RS17240	COG1077	Cell shape determining protein MreB Mrl
OU987_RS17245	COG1609	Transcriptional regulator
OU987_RS17250	COG1846	Transcriptional regulator
OU987_RS17255	COG2814	Major facilitator Superfamily
OU987_RS17260	COG1953	Uracil, thiamine, allantoin
OU987_RS17265	COG0477	Major facilitator Superfamily
OU987_RS17270	COG1335	isochorismatase
OU987_RS17275	COG0004	ammonium transporteR
OU987_RS17280	COG0347	Belongs to the P(II) protein family
OU987_RS17285	COG0772	Belongs to the SEDS family
OU987_RS17290	COG0671	phosphoesterase, PA-phosphatase related
OU987_RS17300	COG0739	heme binding
OU987_RS17305	COG1247	-acetyltransferase
OU987_RS17320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU987_RS17335	COG0726	polysaccharide deacetylase
OU987_RS17345	COG1959	2 iron, 2 sulfur cluster binding
OU987_RS17360	COG0831	urea catabolic process
OU987_RS17365	COG3237	CsbD-like
OU987_RS17370	COG1994	Peptidase M50
OU987_RS17375	COG0457	Tetratricopeptide repeat
OU987_RS17385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OU987_RS17395	COG2304	oxidoreductase activity
OU987_RS17400	COG2304	oxidoreductase activity
OU987_RS17405	COG2385	sporulation resulting in formation of a cellular spore
OU987_RS17410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OU987_RS17420	COG4836	Membrane
OU987_RS17490	COG0698	ribose 5-phosphate isomerase
OU987_RS17495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OU987_RS17505	COG0009	L-threonylcarbamoyladenylate synthase
OU987_RS17510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OU987_RS17530	COG2890	protein-(glutamine-N5) methyltransferase activity
OU987_RS17535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OU987_RS17540	COG0346	lactoylglutathione lyase activity
OU987_RS17545	COG0789	Transcriptional regulator
OU987_RS17550	COG0679	Auxin Efflux Carrier
OU987_RS17555	COG0281	malic enzyme
OU987_RS17570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OU987_RS17580	COG1494	fructose-1,6-bisphosphatase
OU987_RS17585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OU987_RS17595	COG0191	fructose-bisphosphate aldolase activity
OU987_RS17600	COG2204	response regulator
OU987_RS17605	COG4821	SIS domain
OU987_RS17620	COG0247	lactate metabolic process
OU987_RS17620	COG2181	nitrate reductase activity
OU987_RS17625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU987_RS17640	COG1132	(ABC) transporter
OU987_RS17645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU987_RS17655	COG2181	nitrate reductase activity
OU987_RS17660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OU987_RS17665	COG1140	nitrate reductase beta subunit
OU987_RS17670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OU987_RS17675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OU987_RS17685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OU987_RS17690	COG2223	nitrite transmembrane transporter activity
OU987_RS17700	COG4506	Protein conserved in bacteria
OU987_RS17710	COG3391	amine dehydrogenase activity
OU987_RS17715	COG3391	amine dehydrogenase activity
OU987_RS17720	COG0457	Tetratricopeptide repeat
OU987_RS17730	COG0010	Belongs to the arginase family
OU987_RS17735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OU987_RS17740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU987_RS17755	COG1994	Peptidase M50
OU987_RS17760	COG1942	4-Oxalocrotonate Tautomerase
OU987_RS17765	COG1846	Transcriptional regulator
OU987_RS17770	COG0531	amino acid
OU987_RS17775	COG3465	dGTPase activity
OU987_RS17780	COG1078	dGTPase activity
OU987_RS17795	COG1695	Transcriptional regulator
OU987_RS17805	COG1131	(ABC) transporter
OU987_RS17810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU987_RS17840	COG0583	DNA-binding transcription factor activity
OU987_RS17845	COG2855	membrane
OU987_RS17850	COG0280	phosphate acetyltransferase
OU987_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS17865	COG0436	Aminotransferase
OU987_RS17895	COG2814	Major facilitator Superfamily
OU987_RS17900	COG2814	Major facilitator Superfamily
OU987_RS17905	COG0833	amino acid
OU987_RS17910	COG4187	Peptidase family M20/M25/M40
OU987_RS17915	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS17920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OU987_RS17925	COG2205	protein histidine kinase activity
OU987_RS17930	COG0745	RESPONSE REGULATOR receiver
OU987_RS17945	COG1131	(ABC) transporter
OU987_RS17950	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OU987_RS17955	COG1091	dTDP-4-dehydrorhamnose reductase activity
OU987_RS17960	COG1088	dTDP-glucose 4,6-dehydratase activity
OU987_RS17965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OU987_RS17970	COG3980	spore coat polysaccharide biosynthesis protein
OU987_RS17975	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OU987_RS17980	COG2089	acid synthase
OU987_RS17985	COG0456	acetyltransferase
OU987_RS17990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU987_RS17995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU987_RS18000	COG0463	Glycosyl transferase, family 2
OU987_RS18010	COG2363	Small membrane protein
OU987_RS18015	COG2233	PERMEase
OU987_RS18030	COG1216	Glycosyl transferase, family 2
OU987_RS18045	COG1695	Transcriptional regulator
OU987_RS18050	COG0351	phosphomethylpyrimidine kinase
OU987_RS18060	COG1621	beta-fructofuranosidase activity
OU987_RS18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU987_RS18065	COG1263	PTS System
OU987_RS18070	COG3711	transcriptional antiterminator
OU987_RS18080	COG1404	Belongs to the peptidase S8 family
OU987_RS18085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU987_RS18090	COG0778	Nitroreductase
OU987_RS18095	COG0772	Belongs to the SEDS family
OU987_RS18100	COG0454	-acetyltransferase
OU987_RS18120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OU987_RS18125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OU987_RS18130	COG2261	transglycosylase associated protein
OU987_RS18135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OU987_RS18140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OU987_RS18145	COG2246	polysaccharide biosynthetic process
OU987_RS18150	COG1309	transcriptional regulator
OU987_RS18170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OU987_RS18175	COG2837	iron assimilation
OU987_RS18195	COG0583	DNA-binding transcription factor activity
OU987_RS18205	COG1346	cytolysis
OU987_RS18210	COG4895	conserved protein (DUF2196)
OU987_RS18215	COG0789	Transcriptional regulator
OU987_RS18220	COG5504	Zn-dependent protease
OU987_RS18225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OU987_RS18230	COG0346	lactoylglutathione lyase activity
OU987_RS18235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS18240	COG1404	Belongs to the peptidase S8 family
OU987_RS18245	COG1442	glycosyl transferase family 8
OU987_RS18250	COG2357	RelA SpoT domain protein
OU987_RS18255	COG1575	Belongs to the MenA family. Type 1 subfamily
OU987_RS18270	COG1696	Membrane protein involved in D-alanine export
OU987_RS18280	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OU987_RS18285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU987_RS18290	COG1486	melibiose metabolic process
OU987_RS18295	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU987_RS18300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS18305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS18310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU987_RS18310	COG3711	transcriptional antiterminator
OU987_RS18325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS18330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU987_RS18340	COG0640	Transcriptional regulator
OU987_RS18345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OU987_RS18350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS18355	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU987_RS18360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU987_RS18365	COG2723	6-phospho-beta-galactosidase activity
OU987_RS18375	COG1482	cell wall glycoprotein biosynthetic process
OU987_RS18385	COG0753	catalase activity
OU987_RS18390	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OU987_RS18395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OU987_RS18415	COG3279	Response regulator of the LytR AlgR family
OU987_RS18435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OU987_RS18440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OU987_RS18445	COG4988	ABC transporter
OU987_RS18450	COG1294	oxidase, subunit
OU987_RS18455	COG1271	oxidase subunit
OU987_RS18460	COG3493	citrate carrier protein
OU987_RS18465	COG0726	polysaccharide deacetylase
OU987_RS18470	COG3842	ATPase activity
OU987_RS18475	COG2508	Transcriptional regulator
OU987_RS18480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS18490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU987_RS18505	COG4894	glucomannan catabolic process
OU987_RS18510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OU987_RS18515	COG0500	methyltransferase
OU987_RS18520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU987_RS18535	COG0753	catalase activity
OU987_RS18535	COG0693	protein deglycase activity
OU987_RS18540	COG2851	Citrate transporter
OU987_RS18545	COG2273	Hydrolase Family 16
OU987_RS18555	COG2270	Major facilitator Superfamily
OU987_RS18560	COG0513	Belongs to the DEAD box helicase family
OU987_RS18570	COG0697	spore germination
OU987_RS18575	COG0589	response to stress
OU987_RS18635	COG3507	Belongs to the glycosyl hydrolase 43 family
OU987_RS18660	COG0010	Belongs to the arginase family
OU987_RS18665	COG0833	amino acid
OU987_RS18670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OU987_RS18675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU987_RS18685	COG2390	Transcriptional regulator
OU987_RS18690	COG0561	phosphatase activity
OU987_RS18720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU987_RS18725	COG5294	Protein conserved in bacteria
OU987_RS18730	COG0577	efflux transmembrane transporter activity
OU987_RS18735	COG1136	(ABC) transporter
OU987_RS18740	COG2205	protein histidine kinase activity
OU987_RS18745	COG0745	RESPONSE REGULATOR receiver
OU987_RS18750	COG2205	protein histidine kinase activity
OU987_RS18755	COG0745	RESPONSE REGULATOR receiver
OU987_RS18785	COG1082	Xylose isomerase domain protein TIM barrel
OU987_RS18795	COG2814	Major facilitator Superfamily
OU987_RS18825	COG1349	DNA-binding transcription factor activity
OU987_RS18830	COG0667	Aldo Keto reductase
OU987_RS18835	COG2814	Major facilitator Superfamily
OU987_RS18850	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS18855	COG2197	response regulator
OU987_RS18860	COG4585	Histidine kinase
OU987_RS18865	COG3239	Fatty acid desaturase
OU987_RS18870	COG1309	transcriptional regulator
OU987_RS18875	COG1012	belongs to the aldehyde dehydrogenase family
OU987_RS18880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OU987_RS18890	COG0640	Transcriptional regulator
OU987_RS18895	COG2814	Major facilitator Superfamily
OU987_RS18900	COG1714	RDD family
OU987_RS18910	COG0450	alkyl hydroperoxide reductase
OU987_RS18915	COG3634	alkyl hydroperoxide reductase activity
OU987_RS18920	COG3177	Filamentation induced by cAMP protein fic
OU987_RS18925	COG1113	amino acid transport
OU987_RS18935	COG2080	2 iron, 2 sulfur cluster binding
OU987_RS18950	COG2068	MobA-Related Protein
OU987_RS18955	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OU987_RS19010	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OU987_RS19015	COG0667	Aldo Keto reductase
OU987_RS19020	COG0456	acetyltransferase
OU987_RS19030	COG0457	Tetratricopeptide repeat
OU987_RS19035	COG0010	Belongs to the arginase family
OU987_RS19040	COG0833	amino acid
OU987_RS19045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OU987_RS19050	COG5658	integral membrane protein
OU987_RS19055	COG0640	Transcriptional regulator
OU987_RS19060	COG3829	transcription factor binding
OU987_RS19070	COG0488	(ABC) transporter
OU987_RS19085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OU987_RS19090	COG5002	protein histidine kinase activity
OU987_RS19090	COG3850	Histidine kinase
OU987_RS19100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU987_RS19105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OU987_RS19110	COG4853	Protein conserved in bacteria
OU987_RS19115	COG4863	YycH protein
OU987_RS19120	COG5002	protein histidine kinase activity
OU987_RS19125	COG0745	RESPONSE REGULATOR receiver
OU987_RS19155	COG0346	lactoylglutathione lyase activity
OU987_RS19160	COG0305	Participates in initiation and elongation during chromosome replication
OU987_RS19175	COG3093	addiction module antidote protein HigA
OU987_RS19180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OU987_RS19185	COG0297	glycogen (starch) synthase activity
OU987_RS19195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OU987_RS19200	COG0438	transferase activity, transferring glycosyl groups
OU987_RS19220	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OU987_RS19225	COG4241	membrane
OU987_RS19235	COG5577	PFAM Coat F domain
OU987_RS19240	COG1733	regulation of RNA biosynthetic process
OU987_RS19250	COG0697	spore germination
OU987_RS19255	COG1621	beta-fructofuranosidase activity
OU987_RS19260	COG1621	beta-fructofuranosidase activity
OU987_RS19270	COG2318	DinB family
OU987_RS19275	COG2211	Major facilitator Superfamily
OU987_RS19285	COG0778	Nitroreductase
OU987_RS19295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU987_RS19300	COG1846	Transcriptional regulator
OU987_RS19305	COG2153	protein acetylation
OU987_RS19315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OU987_RS19320	COG0583	DNA-binding transcription factor activity
OU987_RS19325	COG1028	Short-chain dehydrogenase reductase Sdr
OU987_RS19330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU987_RS19335	COG0697	spore germination
OU987_RS19365	COG1331	Highly conserved protein containing a thioredoxin domain
OU987_RS19370	COG1266	CAAX protease self-immunity
OU987_RS19375	COG0477	Major facilitator Superfamily
OU987_RS19375	COG2814	Major facilitator Superfamily
OU987_RS19380	COG0346	lactoylglutathione lyase activity
OU987_RS19385	COG1609	Transcriptional regulator
OU987_RS19390	COG0708	Exodeoxyribonuclease III
OU987_RS19395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OU987_RS19400	COG2169	Transcriptional regulator
OU987_RS19410	COG0629	single-stranded DNA binding
OU987_RS19420	COG0012	GTP binding
OU987_RS19425	COG0243	molybdopterin cofactor binding
OU987_RS19430	COG4481	Protein conserved in bacteria
OU987_RS19435	COG3949	Membrane
OU987_RS19450	COG1475	DNA binding
OU987_RS19455	COG1192	Involved in chromosome partitioning
OU987_RS19480	COG1847	R3H domain protein
OU987_RS19485	COG0706	membrane insertase activity