locus-tag	class	description
D2M30_RS00010	COG0592	DNA-directed DNA polymerase activity
D2M30_RS00015	COG2501	S4 domain
D2M30_RS00030	COG0187	DNA topoisomerase II activity
D2M30_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D2M30_RS00070	COG0517	IMP dehydrogenase activity
D2M30_RS00070	COG0516	GMP reductase activity
D2M30_RS00075	COG1686	Belongs to the peptidase S11 family
D2M30_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
D2M30_RS00105	COG1428	Deoxynucleoside kinase
D2M30_RS00110	COG1428	Deoxynucleoside kinase
D2M30_RS00115	COG1388	LysM domain
D2M30_RS00115	COG3858	chitin binding
D2M30_RS00120	COG1335	isochorismatase
D2M30_RS00125	COG0590	tRNA wobble adenosine to inosine editing
D2M30_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D2M30_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D2M30_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D2M30_RS00195	COG3853	Toxic anion resistance protein (TelA)
D2M30_RS00200	COG1982	Orn Lys Arg decarboxylase major
D2M30_RS00210	COG3870	Protein conserved in bacteria
D2M30_RS00215	COG1728	Protein conserved in bacteria
D2M30_RS00220	COG0470	DNA polymerase III
D2M30_RS00225	COG1774	PSP1 C-terminal conserved region
D2M30_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D2M30_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D2M30_RS00250	COG2002	toxin-antitoxin pair type II binding
D2M30_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D2M30_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D2M30_RS00260	COG0084	hydrolase, TatD family'
D2M30_RS00265	COG3583	domain protein
D2M30_RS00265	COG3584	3D domain protein
D2M30_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D2M30_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D2M30_RS00285	COG4466	Protein conserved in bacteria
D2M30_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D2M30_RS00305	COG0251	oxidation-reduction process
D2M30_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D2M30_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D2M30_RS00345	COG2002	toxin-antitoxin pair type II binding
D2M30_RS00350	COG2244	polysaccharide biosynthetic process
D2M30_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D2M30_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D2M30_RS00380	COG1098	S1 RNA binding domain
D2M30_RS00395	COG2208	phosphoserine phosphatase activity
D2M30_RS00400	COG2304	oxidoreductase activity
D2M30_RS00405	COG0515	serine threonine protein kinase
D2M30_RS00410	COG0037	tRNA processing
D2M30_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D2M30_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D2M30_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D2M30_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D2M30_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
D2M30_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D2M30_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D2M30_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D2M30_RS00475	COG1396	sequence-specific DNA binding
D2M30_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D2M30_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D2M30_RS00565	COG4463	regulation of RNA biosynthetic process
D2M30_RS00570	COG3880	PFAM UvrB UvrC protein
D2M30_RS00580	COG0542	response to heat
D2M30_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D2M30_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D2M30_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
D2M30_RS00615	COG1045	serine acetyltransferase
D2M30_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D2M30_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D2M30_RS00635	COG3688	RNA-binding protein containing a PIN domain
D2M30_RS00640	COG1595	DNA-templated transcription, initiation
D2M30_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D2M30_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
D2M30_RS00680	COG2813	Specifically methylates the guanine in position
D2M30_RS00695	COG1358	cellular component organization or biogenesis
D2M30_RS00720	COG0596	Alpha beta hydrolase
D2M30_RS00830	COG0201	protein transport
D2M30_RS00840	COG0024	Methionine aminopeptidase
D2M30_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D2M30_RS00880	COG1122	ATPase activity
D2M30_RS00885	COG1122	ATPase activity
D2M30_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D2M30_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D2M30_RS00910	COG2226	methyltransferase
D2M30_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS00925	COG0489	protein tyrosine kinase activity
D2M30_RS00935	COG2194	sulfuric ester hydrolase activity
D2M30_RS00940	COG0726	polysaccharide deacetylase
D2M30_RS01000	COG0738	Major facilitator superfamily
D2M30_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS01015	COG1063	alcohol dehydrogenase
D2M30_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
D2M30_RS01025	COG0385	Bile acid
D2M30_RS01030	COG2819	hydrolase of the alpha beta superfamily
D2M30_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D2M30_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D2M30_RS01050	COG2207	Transcriptional regulator
D2M30_RS01055	COG3876	Protein conserved in bacteria
D2M30_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
D2M30_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D2M30_RS01070	COG1263	PTS System
D2M30_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D2M30_RS01085	COG1683	Conserved Protein
D2M30_RS01115	COG1595	DNA-templated transcription, initiation
D2M30_RS01120	COG5662	AntiSigma factor
D2M30_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D2M30_RS01130	COG4856	YbbR-like protein
D2M30_RS01170	COG1346	cytolysis
D2M30_RS01175	COG1380	Effector of murein hydrolase LrgA
D2M30_RS01180	COG1846	Transcriptional regulator
D2M30_RS01185	COG1113	amino acid transport
D2M30_RS01190	COG1011	Hydrolase
D2M30_RS01195	COG4585	Histidine kinase
D2M30_RS01200	COG2197	response regulator
D2M30_RS01205	COG1131	(ABC) transporter
D2M30_RS01215	COG1511	domain protein
D2M30_RS01215	COG0842	Transport permease protein
D2M30_RS01245	COG0531	amino acid
D2M30_RS01260	COG0584	glycerophosphoryl diester phosphodiesterase
D2M30_RS01265	COG2271	Major facilitator Superfamily
D2M30_RS01280	COG2368	4-hydroxyphenylacetate
D2M30_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS01295	COG0697	spore germination
D2M30_RS01300	COG2207	Transcriptional regulator
D2M30_RS01300	COG1917	Cupin 2, conserved barrel domain protein
D2M30_RS01320	COG0371	Dehydrogenase
D2M30_RS01330	COG1183	phosphatidylcholine synthase activity
D2M30_RS01335	COG0586	Pfam SNARE associated Golgi protein
D2M30_RS01340	COG0688	phosphatidylethanolamine metabolic process
D2M30_RS01355	COG1301	dicarboxylic acid transport
D2M30_RS01365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS01370	COG0833	amino acid
D2M30_RS01375	COG2040	homocysteine
D2M30_RS01380	COG1115	amino acid carrier protein
D2M30_RS01385	COG2066	Belongs to the glutaminase family
D2M30_RS01390	COG4191	Histidine kinase
D2M30_RS01395	COG0784	Response regulator, receiver
D2M30_RS01400	COG3173	Aminoglycoside phosphotransferase
D2M30_RS01410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D2M30_RS01420	COG0346	lactoylglutathione lyase activity
D2M30_RS01425	COG2259	Doxx family
D2M30_RS01430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS01450	COG3773	Cell wall hydrolase
D2M30_RS01455	COG3540	Alkaline phosphatase
D2M30_RS01460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D2M30_RS01465	COG0805	protein transport
D2M30_RS01470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D2M30_RS01475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D2M30_RS01480	COG0477	Major facilitator Superfamily
D2M30_RS01485	COG1309	transcriptional regulator
D2M30_RS01490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D2M30_RS01495	COG3012	SEC-C Motif Domain Protein
D2M30_RS01495	COG1405	negative regulation of cell septum assembly
D2M30_RS01500	COG0667	Aldo Keto reductase
D2M30_RS01510	COG1595	DNA-templated transcription, initiation
D2M30_RS01515	COG1595	DNA-templated transcription, initiation
D2M30_RS01520	COG1876	peptidase activity
D2M30_RS01525	COG0457	Tetratricopeptide repeat
D2M30_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS01535	COG0366	Alpha amylase catalytic
D2M30_RS01540	COG0803	Belongs to the bacterial solute-binding protein 9 family
D2M30_RS01545	COG1121	(ABC) transporter
D2M30_RS01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D2M30_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS01560	COG2310	stress, protein
D2M30_RS01565	COG2310	stress, protein
D2M30_RS01570	COG2310	stress, protein
D2M30_RS01575	COG0861	Integral membrane protein TerC family
D2M30_RS01585	COG3853	Toxic anion resistance protein (TelA)
D2M30_RS01590	COG0477	Major facilitator Superfamily
D2M30_RS01595	COG0517	IMP dehydrogenase activity
D2M30_RS01595	COG4175	Glycine betaine
D2M30_RS01600	COG4176	ABC-type proline glycine betaine transport system permease component
D2M30_RS01605	COG2113	Glycine betaine
D2M30_RS01610	COG1473	amidohydrolase
D2M30_RS01615	COG1288	antiporter activity
D2M30_RS01625	COG1714	RDD family
D2M30_RS01635	COG2814	Major facilitator Superfamily
D2M30_RS01640	COG1846	Transcriptional regulator
D2M30_RS01645	COG1280	lysine exporter protein (LysE YggA)
D2M30_RS01650	COG3403	YqcI/YcgG family
D2M30_RS01655	COG1113	amino acid transport
D2M30_RS01660	COG3665	Urea carboxylase-associated protein
D2M30_RS01670	COG1082	Xylose isomerase domain protein TIM barrel
D2M30_RS01675	COG2271	Major facilitator Superfamily
D2M30_RS01680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D2M30_RS01685	COG3458	cephalosporin-C deacetylase activity
D2M30_RS01690	COG3541	Predicted nucleotidyltransferase
D2M30_RS01695	COG0506	proline dehydrogenase activity
D2M30_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS01705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D2M30_RS01710	COG2508	Transcriptional regulator
D2M30_RS01720	COG1587	Uroporphyrinogen-III synthase
D2M30_RS01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D2M30_RS01725	COG2146	nitrite reductase [NAD(P)H] activity
D2M30_RS01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D2M30_RS01735	COG2223	nitrite transmembrane transporter activity
D2M30_RS01740	COG0523	cobalamin synthesis protein
D2M30_RS01745	COG1063	alcohol dehydrogenase
D2M30_RS01750	COG1714	RDD family
D2M30_RS01760	COG2723	6-phospho-beta-galactosidase activity
D2M30_RS01770	COG3209	COG3209 Rhs family protein
D2M30_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D2M30_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D2M30_RS01790	COG1733	regulation of RNA biosynthetic process
D2M30_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS01810	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D2M30_RS01825	COG2364	Membrane
D2M30_RS01830	COG1126	abc transporter atp-binding protein
D2M30_RS01835	COG0765	amino acid transport
D2M30_RS01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS01845	COG0583	DNA-binding transcription factor activity
D2M30_RS01850	COG0163	prenyltransferase activity
D2M30_RS01855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D2M30_RS01870	COG3104	oligopeptide transport
D2M30_RS01875	COG5434	Belongs to the glycosyl hydrolase 28 family
D2M30_RS01885	COG0697	spore germination
D2M30_RS01895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D2M30_RS01900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS01905	COG0456	acetyltransferase
D2M30_RS01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS01915	COG0765	amino acid transport
D2M30_RS01920	COG1126	abc transporter atp-binding protein
D2M30_RS01925	COG1473	amidohydrolase
D2M30_RS01930	COG2079	MmgE PrpD family protein
D2M30_RS01935	COG1136	(ABC) transporter
D2M30_RS01940	COG0577	efflux transmembrane transporter activity
D2M30_RS01945	COG0745	RESPONSE REGULATOR receiver
D2M30_RS01950	COG3850	Histidine kinase
D2M30_RS01950	COG5002	protein histidine kinase activity
D2M30_RS01955	COG0457	Tetratricopeptide repeat
D2M30_RS01970	COG0527	aspartate kinase activity
D2M30_RS01975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS01980	COG4605	iron ion homeostasis
D2M30_RS01985	COG4604	ABC transporter, ATP-binding protein
D2M30_RS01990	COG4607	ABC-type enterochelin transport system periplasmic component
D2M30_RS01995	COG2814	Major facilitator Superfamily
D2M30_RS02000	COG1309	transcriptional regulator
D2M30_RS02005	COG0778	Nitroreductase
D2M30_RS02010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D2M30_RS02015	COG0640	Transcriptional regulator
D2M30_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D2M30_RS02025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS02035	COG4975	Glucose uptake
D2M30_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS02045	COG4549	nuclear export factor GLE1
D2M30_RS02050	COG1276	copper resistance
D2M30_RS02050	COG2372	response to copper ion
D2M30_RS02055	COG1349	DNA-binding transcription factor activity
D2M30_RS02065	COG2213	PTS system mannitol-specific
D2M30_RS02070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D2M30_RS02090	COG0561	phosphatase activity
D2M30_RS02100	COG1914	H( )-stimulated, divalent metal cation uptake system
D2M30_RS02110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D2M30_RS02115	COG1984	allophanate hydrolase subunit 2
D2M30_RS02120	COG1414	Transcriptional regulator
D2M30_RS02125	COG2755	lipolytic protein G-D-S-L family
D2M30_RS02135	COG2329	Antibiotic biosynthesis monooxygenase
D2M30_RS02140	COG0768	penicillin binding
D2M30_RS02145	COG4989	oxidoreductase activity
D2M30_RS02150	COG3711	transcriptional antiterminator
D2M30_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS02165	COG1917	Cupin 2, conserved barrel domain protein
D2M30_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D2M30_RS02175	COG3871	stress protein (general stress protein 26)
D2M30_RS02185	COG2814	Major facilitator Superfamily
D2M30_RS02190	COG1522	sequence-specific DNA binding
D2M30_RS02195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D2M30_RS02195	COG0551	DNA topoisomerase type I activity
D2M30_RS02200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D2M30_RS02205	COG3706	GGDEF domain
D2M30_RS02210	COG5298	Protein conserved in bacteria
D2M30_RS02215	COG1215	transferase activity, transferring glycosyl groups
D2M30_RS02225	COG0531	amino acid
D2M30_RS02230	COG0028	Belongs to the TPP enzyme family
D2M30_RS02250	COG1914	H( )-stimulated, divalent metal cation uptake system
D2M30_RS02260	COG4876	unkown
D2M30_RS02270	COG2076	Multidrug Resistance protein
D2M30_RS02275	COG2217	Heavy metal translocating P-type atpase
D2M30_RS02280	COG3729	General stress protein
D2M30_RS02285	COG0662	Cupin 2, conserved barrel domain protein
D2M30_RS02290	COG2329	Antibiotic biosynthesis monooxygenase
D2M30_RS02295	COG3546	catalase activity
D2M30_RS02300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D2M30_RS02305	COG3290	protein histidine kinase activity
D2M30_RS02310	COG4565	transcriptional regulatory protein
D2M30_RS02315	COG1301	dicarboxylic acid transport
D2M30_RS02320	COG0628	permease
D2M30_RS02325	COG1131	(ABC) transporter
D2M30_RS02330	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D2M30_RS02340	COG1960	acyl-CoA dehydrogenase activity
D2M30_RS02360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D2M30_RS02365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS02375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D2M30_RS02380	COG0513	Belongs to the DEAD box helicase family
D2M30_RS02385	COG3402	PFAM membrane-flanked domain
D2M30_RS02390	COG3428	Bacterial PH domain
D2M30_RS02395	COG0705	Rhomboid family
D2M30_RS02415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D2M30_RS02420	COG0864	Transcriptional regulator
D2M30_RS02425	COG2337	Toxic component of a toxin-antitoxin (TA) module
D2M30_RS02430	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS02435	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS02440	COG2172	sigma factor antagonist activity
D2M30_RS02445	COG2208	phosphoserine phosphatase activity
D2M30_RS02450	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS02460	COG1191	sigma factor activity
D2M30_RS02465	COG2208	phosphoserine phosphatase activity
D2M30_RS02470	COG2183	response to ionizing radiation
D2M30_RS02525	COG4124	Belongs to the glycosyl hydrolase 26 family
D2M30_RS02530	COG1846	Transcriptional regulator
D2M30_RS02535	COG0456	acetyltransferase
D2M30_RS02540	COG2808	Putative FMN-binding domain
D2M30_RS02560	COG0457	Tetratricopeptide repeat
D2M30_RS02585	COG1764	response to oxidative stress
D2M30_RS02590	COG1846	Transcriptional regulator
D2M30_RS02595	COG0456	acetyltransferase
D2M30_RS02595	COG1846	Transcriptional regulator
D2M30_RS02600	COG2271	Major facilitator Superfamily
D2M30_RS02605	COG4124	Belongs to the glycosyl hydrolase 26 family
D2M30_RS02625	COG1959	2 iron, 2 sulfur cluster binding
D2M30_RS02640	COG1278	Cold shock
D2M30_RS02645	COG1794	racemase activity, acting on amino acids and derivatives
D2M30_RS02665	COG0477	Major facilitator Superfamily
D2M30_RS02670	COG3621	Patatin-like phospholipase
D2M30_RS02680	COG0277	FAD linked oxidase domain protein
D2M30_RS02700	COG0662	Cupin 2, conserved barrel domain protein
D2M30_RS02710	COG0456	acetyltransferase
D2M30_RS02715	COG2207	Transcriptional regulator
D2M30_RS02715	COG3708	Transcriptional regulator
D2M30_RS02735	COG1064	alcohol dehydrogenase
D2M30_RS02740	COG0789	Transcriptional regulator
D2M30_RS02750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D2M30_RS02755	COG2808	Putative FMN-binding domain
D2M30_RS02765	COG2814	Major facilitator Superfamily
D2M30_RS02770	COG1309	transcriptional regulator
D2M30_RS02775	COG0697	spore germination
D2M30_RS02780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D2M30_RS02785	COG5577	PFAM Coat F domain
D2M30_RS02795	COG1063	alcohol dehydrogenase
D2M30_RS02800	COG5577	PFAM Coat F domain
D2M30_RS02810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D2M30_RS02820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D2M30_RS02825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS02835	COG2814	Major facilitator Superfamily
D2M30_RS02840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D2M30_RS02850	COG0730	response to heat
D2M30_RS02855	COG0456	acetyltransferase
D2M30_RS02860	COG0789	Transcriptional regulator
D2M30_RS02860	COG4978	Transcriptional regulator
D2M30_RS02865	COG0697	spore germination
D2M30_RS02870	COG1051	belongs to the nudix hydrolase family
D2M30_RS02875	COG0596	Alpha beta hydrolase
D2M30_RS02880	COG0473	3-isopropylmalate dehydrogenase activity
D2M30_RS02885	COG1802	Transcriptional regulator
D2M30_RS02890	COG1819	glycosyl
D2M30_RS02900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D2M30_RS02905	COG1388	LysM domain
D2M30_RS02910	COG2814	Major facilitator Superfamily
D2M30_RS02915	COG2188	Transcriptional regulator
D2M30_RS02920	COG2186	Transcriptional regulator
D2M30_RS02925	COG2807	transmembrane transport
D2M30_RS02930	COG2076	Multidrug Resistance protein
D2M30_RS02935	COG2076	Multidrug Resistance protein
D2M30_RS02940	COG1309	transcriptional regulator
D2M30_RS02945	COG0531	amino acid
D2M30_RS02955	COG3832	glyoxalase III activity
D2M30_RS02960	COG0604	alcohol dehydrogenase
D2M30_RS02965	COG2814	Major facilitator Superfamily
D2M30_RS03005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D2M30_RS03010	COG0802	atpase or kinase
D2M30_RS03015	COG1214	PFAM Peptidase M22, glycoprotease
D2M30_RS03020	COG0456	acetyltransferase
D2M30_RS03025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D2M30_RS03030	COG0488	(ABC) transporter
D2M30_RS03045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D2M30_RS03050	COG0805	protein transport
D2M30_RS03060	COG1266	CAAX protease self-immunity
D2M30_RS03080	COG5444	nuclease activity
D2M30_RS03100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D2M30_RS03105	COG0457	Tetratricopeptide repeat
D2M30_RS03110	COG1063	alcohol dehydrogenase
D2M30_RS03115	COG2211	Major facilitator Superfamily
D2M30_RS03120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D2M30_RS03130	COG1842	Phage shock protein A
D2M30_RS03135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D2M30_RS03140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D2M30_RS03145	COG4260	virion core protein, lumpy skin disease virus
D2M30_RS03150	COG2755	lipolytic protein G-D-S-L family
D2M30_RS03150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D2M30_RS03160	COG1595	DNA-templated transcription, initiation
D2M30_RS03165	COG1063	alcohol dehydrogenase
D2M30_RS03170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D2M30_RS03175	COG0823	Involved in the tonB-independent uptake of proteins
D2M30_RS03185	COG2132	Multicopper oxidase
D2M30_RS03190	COG1113	amino acid transport
D2M30_RS03200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D2M30_RS03205	COG0714	Associated with various cellular activities
D2M30_RS03210	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D2M30_RS03215	COG1305	Transglutaminase-like
D2M30_RS03235	COG2252	PERMEase
D2M30_RS03240	COG3064	Membrane
D2M30_RS03260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D2M30_RS03265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D2M30_RS03270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D2M30_RS03275	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D2M30_RS03280	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D2M30_RS03295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D2M30_RS03305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D2M30_RS03310	COG0138	bifunctional purine biosynthesis protein purh
D2M30_RS03315	COG0151	Belongs to the GarS family
D2M30_RS03320	COG1522	sequence-specific DNA binding
D2M30_RS03325	COG0531	amino acid
D2M30_RS03335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D2M30_RS03340	COG1470	cell adhesion involved in biofilm formation
D2M30_RS03345	COG4496	protein, YerC YecD
D2M30_RS03350	COG0069	glutamate synthase activity
D2M30_RS03360	COG0210	DNA helicase
D2M30_RS03370	COG4851	CamS sex pheromone cAM373 precursor
D2M30_RS03375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D2M30_RS03380	COG1285	pathogenesis
D2M30_RS03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D2M30_RS03405	COG1309	transcriptional regulator
D2M30_RS03410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D2M30_RS03415	COG1597	lipid kinase activity
D2M30_RS03420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D2M30_RS03425	COG2197	response regulator
D2M30_RS03435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS03445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D2M30_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS03460	COG1131	(ABC) transporter
D2M30_RS03490	COG5444	nuclease activity
D2M30_RS03510	COG5444	nuclease activity
D2M30_RS03540	COG3546	catalase activity
D2M30_RS03545	COG0454	-acetyltransferase
D2M30_RS03555	COG2323	membrane
D2M30_RS03560	COG2329	Antibiotic biosynthesis monooxygenase
D2M30_RS03565	COG0346	lactoylglutathione lyase activity
D2M30_RS03570	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS03575	COG5583	Uncharacterized small protein (DUF2292)
D2M30_RS03580	COG0196	riboflavin kinase activity
D2M30_RS03585	COG0670	Belongs to the BI1 family
D2M30_RS03595	COG1846	Transcriptional regulator
D2M30_RS03600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D2M30_RS03610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D2M30_RS03610	COG2124	cytochrome p450
D2M30_RS03620	COG1368	sulfuric ester hydrolase activity
D2M30_RS03630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D2M30_RS03635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D2M30_RS03640	COG1442	glycosyl transferase family 8
D2M30_RS03645	COG1216	Glycosyl transferase, family 2
D2M30_RS03650	COG1442	glycosyl transferase family 8
D2M30_RS03655	COG2223	nitrite transmembrane transporter activity
D2M30_RS03660	COG0531	amino acid
D2M30_RS03665	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS03670	COG0840	transmembrane signaling receptor activity
D2M30_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS03680	COG0457	Tetratricopeptide repeat
D2M30_RS03680	COG0463	Glycosyl transferase, family 2
D2M30_RS03685	COG0488	(ABC) transporter
D2M30_RS03690	COG0789	Transcriptional regulator
D2M30_RS03695	COG2814	Major facilitator Superfamily
D2M30_RS03700	COG0488	(ABC) transporter
D2M30_RS03705	COG0513	Belongs to the DEAD box helicase family
D2M30_RS03710	COG2130	NADP-dependent
D2M30_RS03725	COG3866	Pectate lyase
D2M30_RS03730	COG0471	metal ion transport
D2M30_RS03750	COG3290	protein histidine kinase activity
D2M30_RS03755	COG4565	transcriptional regulatory protein
D2M30_RS03760	COG3181	Tripartite tricarboxylate transporter family receptor
D2M30_RS03765	COG2851	Citrate transporter
D2M30_RS03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS03775	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D2M30_RS03785	COG2258	MOSC domain
D2M30_RS03800	COG0024	Methionine aminopeptidase
D2M30_RS03805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS03805	COG1263	PTS System
D2M30_RS03815	COG1368	sulfuric ester hydrolase activity
D2M30_RS03825	COG0071	Belongs to the small heat shock protein (HSP20) family
D2M30_RS03840	COG1263	PTS System
D2M30_RS03840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS03845	COG0366	Alpha amylase catalytic
D2M30_RS03850	COG2188	Transcriptional regulator
D2M30_RS03855	COG0778	Nitroreductase
D2M30_RS03870	COG0737	Belongs to the 5'-nucleotidase family
D2M30_RS03875	COG0693	protein deglycase activity
D2M30_RS03880	COG1609	Transcriptional regulator
D2M30_RS03895	COG2814	Major facilitator Superfamily
D2M30_RS03905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D2M30_RS03910	COG4980	gas vesicle protein
D2M30_RS03915	COG1295	ribonuclease BN
D2M30_RS03925	COG0477	Major facilitator Superfamily
D2M30_RS03930	COG0387	Pfam Sodium calcium exchanger
D2M30_RS03940	COG0668	transmembrane transport
D2M30_RS03945	COG0535	radical SAM domain protein
D2M30_RS03955	COG0726	polysaccharide deacetylase
D2M30_RS03960	COG2084	Dehydrogenase
D2M30_RS03970	COG0598	Magnesium transport protein CorA
D2M30_RS03975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D2M30_RS03980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D2M30_RS03995	COG1132	(ABC) transporter
D2M30_RS04000	COG0515	serine threonine protein kinase
D2M30_RS04010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D2M30_RS04015	COG4637	Psort location Cytoplasmic, score
D2M30_RS04020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D2M30_RS04025	COG0022	dehydrogenase e1 component
D2M30_RS04030	COG0508	dehydrogenase complex catalyzes the overall conversion of
D2M30_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D2M30_RS04040	COG3284	Transcriptional regulator
D2M30_RS04050	COG1486	melibiose metabolic process
D2M30_RS04055	COG1737	Transcriptional regulator
D2M30_RS04060	COG1263	PTS System
D2M30_RS04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS04065	COG5434	Belongs to the glycosyl hydrolase 28 family
D2M30_RS04070	COG1132	(ABC) transporter
D2M30_RS04075	COG1132	(ABC) transporter
D2M30_RS04080	COG2259	Doxx family
D2M30_RS04085	COG2514	catechol 2,3-dioxygenase activity
D2M30_RS04095	COG1695	Transcriptional regulator
D2M30_RS04100	COG2249	NAD(P)H dehydrogenase (quinone) activity
D2M30_RS04105	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D2M30_RS04110	COG2732	(Barnase) inhibitor
D2M30_RS04115	COG2318	DinB family
D2M30_RS04120	COG2814	Major facilitator Superfamily
D2M30_RS04125	COG1846	Transcriptional regulator
D2M30_RS04130	COG0392	lysyltransferase activity
D2M30_RS04130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D2M30_RS04135	COG0384	phenazine biosynthesis protein PhzF
D2M30_RS04140	COG0778	Nitroreductase
D2M30_RS04155	COG1090	epimerase
D2M30_RS04170	COG2814	Major facilitator Superfamily
D2M30_RS04180	COG3591	Belongs to the peptidase S1B family
D2M30_RS04195	COG3103	Sh3 type 3 domain protein
D2M30_RS04200	COG5658	integral membrane protein
D2M30_RS04205	COG0596	Alpha beta hydrolase
D2M30_RS04210	COG0463	Glycosyl transferase, family 2
D2M30_RS04215	COG4485	Bacterial membrane protein, YfhO
D2M30_RS04220	COG1988	membrane-bound metal-dependent
D2M30_RS04225	COG1194	a g-specific adenine glycosylase
D2M30_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS04255	COG1132	(ABC) transporter
D2M30_RS04260	COG4129	membrane
D2M30_RS04270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D2M30_RS04275	COG0735	belongs to the Fur family
D2M30_RS04385	COG1757	Na H antiporter
D2M30_RS04390	COG3340	Belongs to the peptidase S51 family
D2M30_RS04400	COG0277	FAD linked oxidase domain protein
D2M30_RS04410	COG0747	negative chemotaxis
D2M30_RS04415	COG0601	transmembrane transport
D2M30_RS04420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D2M30_RS04425	COG0444	Belongs to the ABC transporter superfamily
D2M30_RS04430	COG4608	Belongs to the ABC transporter superfamily
D2M30_RS04435	COG0753	catalase activity
D2M30_RS04445	COG1116	anion transmembrane transporter activity
D2M30_RS04450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D2M30_RS04455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D2M30_RS04475	COG1476	TRANSCRIPTIONal
D2M30_RS04485	COG3382	B3 4 domain protein
D2M30_RS04490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D2M30_RS04500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D2M30_RS04505	COG0789	Transcriptional regulator
D2M30_RS04510	COG1664	Polymer-forming cytoskeletal
D2M30_RS04515	COG1664	Polymer-forming cytoskeletal
D2M30_RS04520	COG2766	serine protein kinase
D2M30_RS04530	COG1846	Transcriptional regulator
D2M30_RS04535	COG1566	PFAM secretion protein HlyD family protein
D2M30_RS04540	COG2814	Major facilitator Superfamily
D2M30_RS04545	COG0655	NAD(P)H dehydrogenase (quinone) activity
D2M30_RS04560	COG1725	Transcriptional regulator
D2M30_RS04565	COG1131	(ABC) transporter
D2M30_RS04570	COG1131	(ABC) transporter
D2M30_RS04575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D2M30_RS04580	COG1278	Cold shock
D2M30_RS04585	COG1464	Belongs to the NlpA lipoprotein family
D2M30_RS04590	COG3706	GGDEF domain
D2M30_RS04595	COG1823	symporter activity
D2M30_RS04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D2M30_RS04620	COG5577	PFAM Coat F domain
D2M30_RS04625	COG4085	toxin activity
D2M30_RS04625	COG0737	Belongs to the 5'-nucleotidase family
D2M30_RS04625	COG1525	nuclease
D2M30_RS04630	COG3764	Sortase (surface protein transpeptidase)
D2M30_RS04635	COG0564	pseudouridine synthase activity
D2M30_RS04645	COG0517	IMP dehydrogenase activity
D2M30_RS04650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D2M30_RS04655	COG3153	acetyltransferase
D2M30_RS04655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D2M30_RS04660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D2M30_RS04665	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D2M30_RS04670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D2M30_RS04680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D2M30_RS04685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D2M30_RS04690	COG4585	Histidine kinase
D2M30_RS04690	COG2203	Gaf domain
D2M30_RS04695	COG2197	response regulator
D2M30_RS04700	COG0431	NADPH-dependent FMN reductase
D2M30_RS04715	COG1388	LysM domain
D2M30_RS04715	COG0791	NLP P60 protein
D2M30_RS04720	COG1959	2 iron, 2 sulfur cluster binding
D2M30_RS04725	COG0668	transmembrane transport
D2M30_RS04730	COG2719	SpoVR family
D2M30_RS04735	COG1785	Belongs to the alkaline phosphatase family
D2M30_RS04740	COG0791	NLP P60 protein
D2M30_RS04740	COG1388	LysM domain
D2M30_RS04745	COG0583	DNA-binding transcription factor activity
D2M30_RS04750	COG0372	Belongs to the citrate synthase family
D2M30_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS04760	COG0531	amino acid
D2M30_RS04765	COG0733	neurotransmitter:sodium symporter activity
D2M30_RS04780	COG1595	DNA-templated transcription, initiation
D2M30_RS04785	COG0204	Acyl-transferase
D2M30_RS04790	COG1253	flavin adenine dinucleotide binding
D2M30_RS04795	COG0789	Transcriptional regulator
D2M30_RS04800	COG0436	Aminotransferase
D2M30_RS04805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D2M30_RS04810	COG1253	flavin adenine dinucleotide binding
D2M30_RS04815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D2M30_RS04820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D2M30_RS04825	COG0584	glycerophosphoryl diester phosphodiesterase
D2M30_RS04835	COG0668	transmembrane transport
D2M30_RS04840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D2M30_RS04845	COG0726	polysaccharide deacetylase
D2M30_RS04850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS04855	COG3226	Transcriptional regulator
D2M30_RS04865	COG0589	response to stress
D2M30_RS04870	COG1132	(ABC) transporter
D2M30_RS04875	COG1132	(ABC) transporter
D2M30_RS04880	COG0702	epimerase
D2M30_RS04895	COG0189	ligase activity
D2M30_RS04900	COG0189	ligase activity
D2M30_RS04915	COG0561	phosphatase activity
D2M30_RS04920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D2M30_RS04930	COG0475	glutathione-regulated potassium exporter activity
D2M30_RS04935	COG0490	domain, Protein
D2M30_RS04945	COG1024	Enoyl-CoA hydratase
D2M30_RS04955	COG4152	abc transporter atp-binding protein
D2M30_RS04960	COG1668	transmembrane transport
D2M30_RS04965	COG0420	3'-5' exonuclease activity
D2M30_RS04970	COG4717	serine-type aminopeptidase activity
D2M30_RS04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D2M30_RS05025	COG4980	gas vesicle protein
D2M30_RS05040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D2M30_RS05045	COG0537	adenosine 5'-monophosphoramidase activity
D2M30_RS05050	COG1131	(ABC) transporter
D2M30_RS05055	COG4473	ABC transporter
D2M30_RS05065	COG1473	amidohydrolase
D2M30_RS05070	COG3069	C4-dicarboxylate transmembrane transporter activity
D2M30_RS05075	COG2329	Antibiotic biosynthesis monooxygenase
D2M30_RS05080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D2M30_RS05090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D2M30_RS05095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D2M30_RS05100	COG1309	transcriptional regulator
D2M30_RS05105	COG1511	domain protein
D2M30_RS05110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D2M30_RS05120	COG1363	Peptidase, m42
D2M30_RS05125	COG1301	dicarboxylic acid transport
D2M30_RS05135	COG1234	tRNA 3'-trailer cleavage
D2M30_RS05140	COG0095	Lipoate-protein ligase
D2M30_RS05145	COG0702	epimerase
D2M30_RS05150	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS05160	COG0501	Belongs to the peptidase M48B family
D2M30_RS05165	COG1404	Belongs to the peptidase S8 family
D2M30_RS05175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D2M30_RS05180	COG0406	alpha-ribazole phosphatase activity
D2M30_RS05185	COG0183	Belongs to the thiolase family
D2M30_RS05190	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS05195	COG1268	BioY protein
D2M30_RS05200	COG0840	transmembrane signaling receptor activity
D2M30_RS05205	COG0723	plastoquinol--plastocyanin reductase activity
D2M30_RS05205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D2M30_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS05220	COG4903	ComK protein
D2M30_RS05225	COG5646	InterPro IPR014922
D2M30_RS05250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D2M30_RS05265	COG0398	Pfam SNARE associated Golgi protein
D2M30_RS05270	COG0681	Belongs to the peptidase S26 family
D2M30_RS05275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D2M30_RS05280	COG1846	Transcriptional regulator
D2M30_RS05285	COG3180	Ammonia monooxygenase
D2M30_RS05290	COG2814	Major facilitator Superfamily
D2M30_RS05300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D2M30_RS05305	COG2323	membrane
D2M30_RS05320	COG0420	3'-5' exonuclease activity
D2M30_RS05325	COG0419	ATPase involved in DNA repair
D2M30_RS05330	COG1403	HNH endonuclease
D2M30_RS05370	COG0179	Fumarylacetoacetate (FAA) hydrolase
D2M30_RS05380	COG1404	Belongs to the peptidase S8 family
D2M30_RS05390	COG0367	asparagine synthase
D2M30_RS05395	COG1562	ergosterol biosynthetic process
D2M30_RS05400	COG0534	Mate efflux family protein
D2M30_RS05405	COG1917	Cupin 2, conserved barrel domain protein
D2M30_RS05405	COG2207	Transcriptional regulator
D2M30_RS05410	COG1609	Transcriptional regulator
D2M30_RS05415	COG0673	inositol 2-dehydrogenase activity
D2M30_RS05420	COG2318	DinB family
D2M30_RS05425	COG1279	arginine transmembrane transporter activity
D2M30_RS05430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D2M30_RS05435	COG1357	PFAM Pentapeptide repeats (8 copies)
D2M30_RS05440	COG2153	protein acetylation
D2M30_RS05445	COG0646	methionine synthase
D2M30_RS05445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D2M30_RS05455	COG2996	Protein conserved in bacteria
D2M30_RS05460	COG1744	ABC transporter substrate-binding protein PnrA-like
D2M30_RS05465	COG0840	transmembrane signaling receptor activity
D2M30_RS05470	COG2124	cytochrome p450
D2M30_RS05480	COG1307	EDD domain protein, DegV family
D2M30_RS05485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS05500	COG0561	phosphatase activity
D2M30_RS05505	COG1073	alpha beta
D2M30_RS05510	COG2151	metal-sulfur cluster biosynthetic enzyme
D2M30_RS05520	COG0277	FAD linked oxidase domain protein
D2M30_RS05525	COG2271	Major facilitator Superfamily
D2M30_RS05535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D2M30_RS05545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D2M30_RS05550	COG0505	Belongs to the CarA family
D2M30_RS05555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D2M30_RS05560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D2M30_RS05580	COG2267	carboxylic ester hydrolase activity
D2M30_RS05590	COG1744	ABC transporter substrate-binding protein PnrA-like
D2M30_RS05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D2M30_RS05610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D2M30_RS05615	COG5504	Zn-dependent protease
D2M30_RS05620	COG0444	Belongs to the ABC transporter superfamily
D2M30_RS05625	COG4608	Belongs to the ABC transporter superfamily
D2M30_RS05635	COG0601	transmembrane transport
D2M30_RS05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D2M30_RS05650	COG0180	Tryptophanyl-tRNA synthetase
D2M30_RS05660	COG4166	transmembrane transport
D2M30_RS05665	COG0601	transmembrane transport
D2M30_RS05670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D2M30_RS05675	COG0444	Belongs to the ABC transporter superfamily
D2M30_RS05680	COG4608	Belongs to the ABC transporter superfamily
D2M30_RS05690	COG0456	acetyltransferase
D2M30_RS05695	COG1393	Belongs to the ArsC family
D2M30_RS05700	COG0861	Integral membrane protein TerC family
D2M30_RS05705	COG4862	establishment of competence for transformation
D2M30_RS05710	COG4469	Competence protein
D2M30_RS05715	COG1164	Oligoendopeptidase f
D2M30_RS05720	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D2M30_RS05725	COG2346	COG2346, Truncated hemoglobins
D2M30_RS05730	COG0741	lytic transglycosylase activity
D2M30_RS05735	COG4116	CYTH
D2M30_RS05745	COG2357	RelA SpoT domain protein
D2M30_RS05750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D2M30_RS05755	COG0564	pseudouridine synthase activity
D2M30_RS05765	COG0569	domain protein
D2M30_RS05765	COG0475	glutathione-regulated potassium exporter activity
D2M30_RS05770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D2M30_RS05775	COG0352	thiamine-phosphate diphosphorylase activity
D2M30_RS05780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D2M30_RS05785	COG2104	thiamine diphosphate biosynthetic process
D2M30_RS05795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D2M30_RS05800	COG0351	phosphomethylpyrimidine kinase
D2M30_RS05805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D2M30_RS05860	COG0210	DNA helicase
D2M30_RS05870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS05880	COG1131	(ABC) transporter
D2M30_RS05890	COG2153	protein acetylation
D2M30_RS05900	COG2382	esterase
D2M30_RS05905	COG0626	cystathionine gamma-synthase activity
D2M30_RS05910	COG0626	cystathionine gamma-synthase activity
D2M30_RS05930	COG4974	Belongs to the 'phage' integrase family
D2M30_RS06135	COG2367	Beta-lactamase
D2M30_RS06140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D2M30_RS06150	COG1846	Transcriptional regulator
D2M30_RS06170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS06170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS06175	COG1447	Phosphotransferase system cellobiose-specific component IIA
D2M30_RS06185	COG1349	DNA-binding transcription factor activity
D2M30_RS06205	COG1285	pathogenesis
D2M30_RS06215	COG2205	protein histidine kinase activity
D2M30_RS06225	COG3383	formate dehydrogenase (NAD+) activity
D2M30_RS06230	COG2427	Protein of unknown function (DUF1641)
D2M30_RS06235	COG2124	cytochrome p450
D2M30_RS06240	COG1819	glycosyl
D2M30_RS06250	COG1587	Uroporphyrinogen-III synthase
D2M30_RS06255	COG0390	transport system, permease component
D2M30_RS06260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D2M30_RS06265	COG0697	spore germination
D2M30_RS06270	COG4297	protein containing double-stranded beta helix domain
D2M30_RS06280	COG1252	NADH dehydrogenase
D2M30_RS06290	COG1609	Transcriptional regulator
D2M30_RS06300	COG0745	RESPONSE REGULATOR receiver
D2M30_RS06305	COG5002	protein histidine kinase activity
D2M30_RS06320	COG0730	response to heat
D2M30_RS06325	COG2318	DinB family
D2M30_RS06330	COG0457	Tetratricopeptide repeat
D2M30_RS06335	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS06335	COG5632	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS06335	COG1388	LysM domain
D2M30_RS06345	COG4195	phage-related replication protein
D2M30_RS06350	COG2856	Zn peptidase
D2M30_RS06355	COG1396	sequence-specific DNA binding
D2M30_RS06365	COG1522	sequence-specific DNA binding
D2M30_RS06370	COG1484	DNA-dependent DNA replication
D2M30_RS06385	COG1595	DNA-templated transcription, initiation
D2M30_RS06390	COG5484	DNA packaging
D2M30_RS06390	COG3728	DNA packaging
D2M30_RS06395	COG1783	phage Terminase large subunit
D2M30_RS06400	COG5518	Phage portal protein
D2M30_RS06405	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D2M30_RS06410	COG4653	Phage capsid family
D2M30_RS06460	COG3953	SLT domain
D2M30_RS06460	COG5412	phage tail tape measure protein
D2M30_RS06460	COG3953	SLT domain
D2M30_RS06460	COG5412	phage tail tape measure protein
D2M30_RS06465	COG1652	LysM domain
D2M30_RS06470	COG4193	domain, Protein
D2M30_RS06480	COG3628	GPW Gp25 family protein
D2M30_RS06485	COG3299	homolog of phage Mu protein gp47
D2M30_RS06490	COG3778	Protein conserved in bacteria
D2M30_RS06530	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS06530	COG5632	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS06545	COG0306	phosphate transporter
D2M30_RS06550	COG1392	Phosphate transport regulator
D2M30_RS06555	COG0531	amino acid
D2M30_RS06560	COG0346	lactoylglutathione lyase activity
D2M30_RS06565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D2M30_RS06570	COG0463	Glycosyl transferase, family 2
D2M30_RS06575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D2M30_RS06580	COG0477	Major facilitator Superfamily
D2M30_RS06585	COG2362	D-Aminopeptidase
D2M30_RS06590	COG0601	transmembrane transport
D2M30_RS06595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D2M30_RS06600	COG0444	Belongs to the ABC transporter superfamily
D2M30_RS06605	COG4166	transmembrane transport
D2M30_RS06610	COG1619	proteins homologs of microcin C7 resistance protein MccF
D2M30_RS06615	COG4948	Mandelate Racemase Muconate Lactonizing
D2M30_RS06620	COG0791	NLP P60 protein
D2M30_RS06625	COG4608	Belongs to the ABC transporter superfamily
D2M30_RS06630	COG2706	6-phosphogluconolactonase activity
D2M30_RS06635	COG1834	amidinotransferase
D2M30_RS06640	COG1607	acyl-coa hydrolase
D2M30_RS06645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D2M30_RS06650	COG2076	Multidrug Resistance protein
D2M30_RS06655	COG2076	Multidrug Resistance protein
D2M30_RS06660	COG0788	formyltetrahydrofolate deformylase activity
D2M30_RS06665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D2M30_RS06675	COG1764	response to oxidative stress
D2M30_RS06680	COG1846	Transcriptional regulator
D2M30_RS06685	COG1764	response to oxidative stress
D2M30_RS06700	COG0457	Tetratricopeptide repeat
D2M30_RS06700	COG0463	Glycosyl transferase, family 2
D2M30_RS06715	COG2814	Major facilitator Superfamily
D2M30_RS06720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D2M30_RS06730	COG1404	Belongs to the peptidase S8 family
D2M30_RS06735	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS06740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D2M30_RS06745	COG1122	ATPase activity
D2M30_RS06750	COG4721	ABC-type cobalt transport system, permease component
D2M30_RS06755	COG3858	chitin binding
D2M30_RS06755	COG1388	LysM domain
D2M30_RS06770	COG2239	Acts as a magnesium transporter
D2M30_RS06775	COG0789	Transcriptional regulator
D2M30_RS06790	COG1846	Transcriptional regulator
D2M30_RS06795	COG0726	polysaccharide deacetylase
D2M30_RS06800	COG3285	dna ligase
D2M30_RS06800	COG1793	dna ligase
D2M30_RS06805	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D2M30_RS06810	COG3300	MHYT domain
D2M30_RS06810	COG5001	Diguanylate cyclase
D2M30_RS06815	COG0586	Pfam SNARE associated Golgi protein
D2M30_RS06820	COG0861	Integral membrane protein TerC family
D2M30_RS06825	COG1191	sigma factor activity
D2M30_RS06850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D2M30_RS06855	COG2323	membrane
D2M30_RS06865	COG3594	Acyltransferase
D2M30_RS06870	COG5002	protein histidine kinase activity
D2M30_RS06875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D2M30_RS06890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D2M30_RS06895	COG0436	Aminotransferase
D2M30_RS06930	COG3852	Histidine kinase
D2M30_RS06935	COG1846	Transcriptional regulator
D2M30_RS06940	COG1360	Flagellar Motor Protein
D2M30_RS06945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D2M30_RS06950	COG0542	response to heat
D2M30_RS06960	COG3949	Membrane
D2M30_RS06975	COG0720	synthase
D2M30_RS06980	COG0602	queuosine metabolic process
D2M30_RS06995	COG4873	Protein conserved in bacteria
D2M30_RS07005	COG3773	Cell wall hydrolase
D2M30_RS07010	COG2244	polysaccharide biosynthetic process
D2M30_RS07015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS07020	COG2217	Heavy metal translocating P-type atpase
D2M30_RS07025	COG0006	proline dipeptidase activity
D2M30_RS07030	COG1609	Transcriptional regulator
D2M30_RS07035	COG3711	transcriptional antiterminator
D2M30_RS07040	COG2190	(PTS) system
D2M30_RS07040	COG1263	PTS System
D2M30_RS07040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS07045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS07050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D2M30_RS07060	COG1533	DNA photolyase activity
D2M30_RS07065	COG0840	transmembrane signaling receptor activity
D2M30_RS07070	COG2084	Dehydrogenase
D2M30_RS07075	COG2340	Cysteine-rich secretory protein family
D2M30_RS07080	COG0768	penicillin binding
D2M30_RS07085	COG4191	Histidine kinase
D2M30_RS07090	COG0436	Aminotransferase
D2M30_RS07100	COG0784	Response regulator, receiver
D2M30_RS07100	COG0835	chemotaxis
D2M30_RS07110	COG2814	Major facilitator Superfamily
D2M30_RS07115	COG1376	ErfK ybiS ycfS ynhG family protein
D2M30_RS07120	COG1408	metallophosphoesterase
D2M30_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS07135	COG2200	EAL domain
D2M30_RS07140	COG4703	Protein of unknown function (DUF1797)
D2M30_RS07145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D2M30_RS07155	COG0517	IMP dehydrogenase activity
D2M30_RS07160	COG0583	DNA-binding transcription factor activity
D2M30_RS07165	COG0716	FMN binding
D2M30_RS07175	COG0716	FMN binding
D2M30_RS07195	COG0668	transmembrane transport
D2M30_RS07205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS07225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D2M30_RS07230	COG0303	'Molybdopterin
D2M30_RS07235	COG1763	Mo-molybdopterin cofactor biosynthetic process
D2M30_RS07240	COG0314	molybdopterin synthase activity
D2M30_RS07245	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D2M30_RS07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D2M30_RS07260	COG1136	(ABC) transporter
D2M30_RS07265	COG0577	efflux transmembrane transporter activity
D2M30_RS07270	COG1349	DNA-binding transcription factor activity
D2M30_RS07275	COG1105	Belongs to the carbohydrate kinase PfkB family
D2M30_RS07280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D2M30_RS07280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D2M30_RS07285	COG0681	Belongs to the peptidase S26 family
D2M30_RS07295	COG0488	(ABC) transporter
D2M30_RS07300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D2M30_RS07305	COG2309	aminopeptidase activity
D2M30_RS07315	COG1077	Cell shape determining protein MreB Mrl
D2M30_RS07325	COG2002	toxin-antitoxin pair type II binding
D2M30_RS07330	COG3852	Histidine kinase
D2M30_RS07335	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D2M30_RS07335	COG2105	PFAM AIG2 family protein
D2M30_RS07340	COG0569	domain protein
D2M30_RS07350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D2M30_RS07365	COG0561	phosphatase activity
D2M30_RS07370	COG0242	peptide deformylase activity
D2M30_RS07380	COG0497	DNA recombination
D2M30_RS07395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS07395	COG3321	synthase
D2M30_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS07395	COG4221	oxidoreductase activity
D2M30_RS07400	COG3321	synthase
D2M30_RS07400	COG4221	oxidoreductase activity
D2M30_RS07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS07400	COG0300	oxidoreductase activity
D2M30_RS07410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS07410	COG3321	synthase
D2M30_RS07410	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS07410	COG0300	oxidoreductase activity
D2M30_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS07415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS07415	COG0300	oxidoreductase activity
D2M30_RS07415	COG3321	synthase
D2M30_RS07415	COG4221	oxidoreductase activity
D2M30_RS07420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS07420	COG4221	oxidoreductase activity
D2M30_RS07420	COG3321	synthase
D2M30_RS07420	COG0300	oxidoreductase activity
D2M30_RS07425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS07425	COG4221	oxidoreductase activity
D2M30_RS07425	COG3321	synthase
D2M30_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS07430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D2M30_RS07435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D2M30_RS07440	COG0022	dehydrogenase e1 component
D2M30_RS07445	COG0508	dehydrogenase complex catalyzes the overall conversion of
D2M30_RS07450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D2M30_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS07530	COG1217	gtp-binding protein TYPA
D2M30_RS07540	COG4896	Protein conserved in bacteria
D2M30_RS07550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D2M30_RS07555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D2M30_RS07560	COG2066	Belongs to the glutaminase family
D2M30_RS07570	COG0772	Belongs to the SEDS family
D2M30_RS07575	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D2M30_RS07590	COG2010	Cytochrome c
D2M30_RS07590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D2M30_RS07595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D2M30_RS07600	COG1845	cytochrome c oxidase, subunit III
D2M30_RS07605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D2M30_RS07610	COG3336	cytochrome c oxidase
D2M30_RS07620	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D2M30_RS07625	COG2340	Cysteine-rich secretory protein family
D2M30_RS07640	COG3679	Belongs to the UPF0342 family
D2M30_RS07650	COG0742	ribosomal rna small subunit methyltransferase
D2M30_RS07660	COG3314	Sporulation integral membrane protein YlbJ
D2M30_RS07665	COG1752	Esterase of the alpha-beta hydrolase superfamily
D2M30_RS07670	COG3480	Lon protease (S16) C-terminal proteolytic domain
D2M30_RS07680	COG1399	metal-binding, possibly nucleic acid-binding protein
D2M30_RS07700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D2M30_RS07720	COG4839	cell division protein FtsL
D2M30_RS07725	COG0768	penicillin binding
D2M30_RS07730	COG0768	penicillin binding
D2M30_RS07750	COG0772	Belongs to the SEDS family
D2M30_RS07765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D2M30_RS07770	COG0849	cell division
D2M30_RS07775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D2M30_RS07780	COG1404	Belongs to the peptidase S8 family
D2M30_RS07780	COG4412	M6 family metalloprotease domain protein
D2M30_RS07790	COG1191	sigma factor activity
D2M30_RS07795	COG1191	sigma factor activity
D2M30_RS07800	COG1119	ATPase activity
D2M30_RS07805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D2M30_RS07810	COG1873	PFAM PRC-barrel domain
D2M30_RS07815	COG1496	oxidoreductase activity
D2M30_RS07820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D2M30_RS07830	COG0762	integral membrane protein
D2M30_RS07835	COG2302	S4 RNA-binding domain
D2M30_RS07840	COG3599	regulation of cell shape
D2M30_RS07850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D2M30_RS07855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D2M30_RS07865	COG0564	pseudouridine synthase activity
D2M30_RS07875	COG2233	PERMEase
D2M30_RS07885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D2M30_RS07890	COG0505	Belongs to the CarA family
D2M30_RS07895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D2M30_RS07910	COG0284	orotidine-5'-phosphate decarboxylase activity
D2M30_RS07915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D2M30_RS07925	COG0306	phosphate transporter
D2M30_RS07940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D2M30_RS07945	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D2M30_RS07950	COG1648	precorrin-2 dehydrogenase activity
D2M30_RS07965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D2M30_RS07970	COG1561	YicC-like family, N-terminal region
D2M30_RS07980	COG0194	GDP metabolic process
D2M30_RS07990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D2M30_RS07995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D2M30_RS08000	COG0242	peptide deformylase activity
D2M30_RS08010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D2M30_RS08010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D2M30_RS08020	COG0631	protein serine/threonine phosphatase activity
D2M30_RS08025	COG2815	serine threonine protein kinase
D2M30_RS08025	COG0515	serine threonine protein kinase
D2M30_RS08035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D2M30_RS08040	COG1564	THIamine pyrophosphokinase
D2M30_RS08055	COG1302	Protein conserved in bacteria
D2M30_RS08060	COG1461	Dihydroxyacetone kinase
D2M30_RS08065	COG1760	l-serine dehydratase
D2M30_RS08070	COG1760	l-serine dehydratase
D2M30_RS08075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D2M30_RS08090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D2M30_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS08110	COG1196	nuclear chromosome segregation
D2M30_RS08115	COG0552	protein localization to endoplasmic reticulum
D2M30_RS08125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D2M30_RS08135	COG1837	Belongs to the UPF0109 family
D2M30_RS08160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D2M30_RS08175	COG2257	FlhB HrpN YscU SpaS Family
D2M30_RS08185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D2M30_RS08190	COG0758	DNA mediated transformation
D2M30_RS08195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D2M30_RS08205	COG4974	Belongs to the 'phage' integrase family
D2M30_RS08225	COG1815	bacterial-type flagellum-dependent cell motility
D2M30_RS08230	COG1558	bacterial-type flagellum-dependent cell motility
D2M30_RS08235	COG1677	Flagellar hook-basal body complex protein FliE
D2M30_RS08240	COG1766	The M ring may be actively involved in energy transduction
D2M30_RS08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D2M30_RS08250	COG1317	bacterial-type flagellum organization
D2M30_RS08255	COG1157	protein secretion by the type III secretion system
D2M30_RS08260	COG2882	bacterial-type flagellum organization
D2M30_RS08265	COG3334	PFAM MgtE intracellular
D2M30_RS08270	COG3144	bacterial-type flagellum assembly
D2M30_RS08275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D2M30_RS08280	COG4786	Flagellar basal body rod
D2M30_RS08285	COG1582	Flagellar protein (FlbD)
D2M30_RS08290	COG1580	Controls the rotational direction of flagella during chemotaxis
D2M30_RS08295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D2M30_RS08300	COG1776	CheC inhibitor of MCP methylation
D2M30_RS08300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D2M30_RS08305	COG2201	protein-glutamate methylesterase activity
D2M30_RS08310	COG3190	flagellar
D2M30_RS08315	COG1338	Plays a role in the flagellum-specific transport system
D2M30_RS08320	COG1987	bacterial-type flagellum assembly
D2M30_RS08325	COG1684	flagellar biosynthetic protein fliR
D2M30_RS08330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D2M30_RS08335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D2M30_RS08340	COG1419	protein localization to endoplasmic reticulum
D2M30_RS08345	COG0455	bacterial-type flagellum organization
D2M30_RS08350	COG2201	protein-glutamate methylesterase activity
D2M30_RS08355	COG0643	Histidine kinase
D2M30_RS08355	COG2198	Histidine kinase
D2M30_RS08360	COG0835	chemotaxis
D2M30_RS08365	COG1776	CheC inhibitor of MCP methylation
D2M30_RS08375	COG1191	sigma factor activity
D2M30_RS08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D2M30_RS08410	COG4589	Belongs to the CDS family
D2M30_RS08420	COG0750	zinc metalloprotease
D2M30_RS08430	COG2176	DNA-directed DNA polymerase activity
D2M30_RS08440	COG0195	Participates in both transcription termination and antitermination
D2M30_RS08445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D2M30_RS08450	COG1358	cellular component organization or biogenesis
D2M30_RS08460	COG1550	Protein conserved in bacteria
D2M30_RS08475	COG0196	riboflavin kinase activity
D2M30_RS08490	COG0726	polysaccharide deacetylase
D2M30_RS08495	COG0612	Peptidase, M16
D2M30_RS08500	COG1873	PFAM PRC-barrel domain
D2M30_RS08505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D2M30_RS08510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D2M30_RS08515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D2M30_RS08520	COG0527	aspartate kinase activity
D2M30_RS08530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D2M30_RS08535	COG0740	serine-type endopeptidase activity
D2M30_RS08545	COG1674	ftsk spoiiie
D2M30_RS08545	COG4980	gas vesicle protein
D2M30_RS08550	COG2188	Transcriptional regulator
D2M30_RS08555	COG2814	Major facilitator Superfamily
D2M30_RS08560	COG1846	Transcriptional regulator
D2M30_RS08565	COG1033	growth of symbiont in host cell
D2M30_RS08565	COG2409	Drug exporters of the RND superfamily
D2M30_RS08570	COG0612	Peptidase, M16
D2M30_RS08575	COG0612	Peptidase, M16
D2M30_RS08580	COG0300	oxidoreductase activity
D2M30_RS08595	COG1426	Protein conserved in bacteria
D2M30_RS08600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D2M30_RS08615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D2M30_RS08625	COG1692	metallophosphoesterase
D2M30_RS08630	COG2359	stage V sporulation protein S
D2M30_RS08650	COG4550	Control of competence regulator ComK, YlbF/YmcA
D2M30_RS08690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS08695	COG3425	synthase
D2M30_RS08700	COG1024	Enoyl-CoA hydratase
D2M30_RS08705	COG1024	Enoyl-CoA hydratase
D2M30_RS08710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS08710	COG0300	oxidoreductase activity
D2M30_RS08710	COG3321	synthase
D2M30_RS08710	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS08715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS08715	COG0300	oxidoreductase activity
D2M30_RS08715	COG3321	synthase
D2M30_RS08715	COG4221	oxidoreductase activity
D2M30_RS08720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS08720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D2M30_RS08720	COG3321	synthase
D2M30_RS08720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS08720	COG3321	synthase
D2M30_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS08720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS08720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS08720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D2M30_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS08725	COG3321	synthase
D2M30_RS08725	COG4221	oxidoreductase activity
D2M30_RS08725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS08730	COG3321	synthase
D2M30_RS08730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D2M30_RS08730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D2M30_RS08730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D2M30_RS08735	COG2124	cytochrome p450
D2M30_RS08740	COG3209	COG3209 Rhs family protein
D2M30_RS08745	COG3619	membrane
D2M30_RS08755	COG1404	Belongs to the peptidase S8 family
D2M30_RS08765	COG4195	phage-related replication protein
D2M30_RS08770	COG1764	response to oxidative stress
D2M30_RS08780	COG2076	Multidrug Resistance protein
D2M30_RS08820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D2M30_RS08825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D2M30_RS08830	COG4112	unkown
D2M30_RS08835	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS08845	COG0464	growth
D2M30_RS08850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D2M30_RS08855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D2M30_RS08860	COG0789	Transcriptional regulator
D2M30_RS08865	COG0174	glutamine synthetase
D2M30_RS08870	COG0726	polysaccharide deacetylase
D2M30_RS08875	COG2124	cytochrome p450
D2M30_RS08880	COG2211	Major facilitator Superfamily
D2M30_RS08885	COG3507	Belongs to the glycosyl hydrolase 43 family
D2M30_RS08900	COG1070	Carbohydrate kinase
D2M30_RS08910	COG0574	Belongs to the PEP-utilizing enzyme family
D2M30_RS08910	COG3848	Pyruvate phosphate dikinase
D2M30_RS08935	COG2318	DinB family
D2M30_RS08940	COG1064	alcohol dehydrogenase
D2M30_RS09000	COG3397	chitin binding
D2M30_RS09020	COG5434	Belongs to the glycosyl hydrolase 28 family
D2M30_RS09025	COG2314	TM2 domain
D2M30_RS09030	COG0756	dUTP diphosphatase activity
D2M30_RS09040	COG4195	phage-related replication protein
D2M30_RS09070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D2M30_RS09080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D2M30_RS09100	COG0785	Cytochrome C biogenesis protein
D2M30_RS09105	COG2201	protein-glutamate methylesterase activity
D2M30_RS09110	COG4846	Membrane protein involved in cytochrome C biogenesis
D2M30_RS09120	COG0071	Belongs to the small heat shock protein (HSP20) family
D2M30_RS09135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D2M30_RS09140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS09160	COG0824	Thioesterase
D2M30_RS09170	COG4841	protein insertion into membrane
D2M30_RS09180	COG1832	CoA-binding protein
D2M30_RS09185	COG0187	DNA topoisomerase II activity
D2M30_RS09190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D2M30_RS09200	COG1115	amino acid carrier protein
D2M30_RS09225	COG2205	protein histidine kinase activity
D2M30_RS09230	COG0745	RESPONSE REGULATOR receiver
D2M30_RS09240	COG3507	Belongs to the glycosyl hydrolase 43 family
D2M30_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS09275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D2M30_RS09280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D2M30_RS09285	COG2124	cytochrome p450
D2M30_RS09305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D2M30_RS09315	COG2246	polysaccharide biosynthetic process
D2M30_RS09320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D2M30_RS09325	COG0586	Pfam SNARE associated Golgi protein
D2M30_RS09330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D2M30_RS09335	COG1024	Enoyl-CoA hydratase
D2M30_RS09340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D2M30_RS09345	COG0511	ligase activity, forming carbon-carbon bonds
D2M30_RS09350	COG0439	Biotin carboxylase
D2M30_RS09355	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS09360	COG1960	acyl-CoA dehydrogenase activity
D2M30_RS09365	COG1649	PFAM Uncharacterised BCR, COG1649
D2M30_RS09375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS09375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D2M30_RS09380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS09385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS09405	COG2027	D-alanyl-D-alanine carboxypeptidase
D2M30_RS09410	COG2017	converts alpha-aldose to the beta-anomer
D2M30_RS09415	COG0534	Mate efflux family protein
D2M30_RS09425	COG5444	nuclease activity
D2M30_RS09460	COG0582	viral genome integration into host DNA
D2M30_RS09465	COG0166	Belongs to the GPI family
D2M30_RS09470	COG0405	Gamma-glutamyltransferase
D2M30_RS09475	COG2814	Major facilitator Superfamily
D2M30_RS09480	COG0640	Transcriptional regulator
D2M30_RS09485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D2M30_RS09495	COG0604	alcohol dehydrogenase
D2M30_RS09505	COG0493	'glutamate synthase
D2M30_RS09510	COG0069	glutamate synthase activity
D2M30_RS09510	COG0070	glutamate synthase
D2M30_RS09510	COG0067	glutamate synthase
D2M30_RS09515	COG0583	DNA-binding transcription factor activity
D2M30_RS09520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D2M30_RS09535	COG0300	oxidoreductase activity
D2M30_RS09540	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D2M30_RS09550	COG2814	Major facilitator Superfamily
D2M30_RS09555	COG1070	Carbohydrate kinase
D2M30_RS09560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D2M30_RS09565	COG0243	molybdopterin cofactor binding
D2M30_RS09620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D2M30_RS09625	COG2207	Transcriptional regulator
D2M30_RS09625	COG0662	Cupin 2, conserved barrel domain protein
D2M30_RS09630	COG1309	transcriptional regulator
D2M30_RS09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS09645	COG0640	Transcriptional regulator
D2M30_RS09650	COG0741	lytic transglycosylase activity
D2M30_RS09655	COG2322	membrane
D2M30_RS09670	COG1619	proteins homologs of microcin C7 resistance protein MccF
D2M30_RS09680	COG3584	3D domain protein
D2M30_RS09680	COG1388	LysM domain
D2M30_RS09685	COG0514	ATP-dependent DNA helicase (RecQ)
D2M30_RS09695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D2M30_RS09700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D2M30_RS09715	COG0071	Belongs to the small heat shock protein (HSP20) family
D2M30_RS09745	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS09750	COG1657	PFAM Prenyltransferase squalene oxidase
D2M30_RS09755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D2M30_RS09760	COG0733	neurotransmitter:sodium symporter activity
D2M30_RS09765	COG0385	Bile acid
D2M30_RS09770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS09775	COG0508	dehydrogenase complex catalyzes the overall conversion of
D2M30_RS09785	COG4548	von Willebrand factor, type A
D2M30_RS09790	COG0714	Associated with various cellular activities
D2M30_RS09795	COG2032	superoxide dismutase activity
D2M30_RS09800	COG0791	NLP P60 protein
D2M30_RS09800	COG1388	LysM domain
D2M30_RS09810	COG1819	glycosyl
D2M30_RS09815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D2M30_RS09820	COG0534	Mate efflux family protein
D2M30_RS09825	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS09830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D2M30_RS09835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D2M30_RS09845	COG2962	Rard protein
D2M30_RS09860	COG1942	4-Oxalocrotonate Tautomerase
D2M30_RS09870	COG1733	regulation of RNA biosynthetic process
D2M30_RS09875	COG0778	Nitroreductase
D2M30_RS09880	COG0400	carboxylic ester hydrolase activity
D2M30_RS09885	COG0346	lactoylglutathione lyase activity
D2M30_RS09895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D2M30_RS09905	COG2723	6-phospho-beta-galactosidase activity
D2M30_RS09910	COG2188	Transcriptional regulator
D2M30_RS09915	COG0793	Belongs to the peptidase S41A family
D2M30_RS09915	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS09920	COG2226	methyltransferase
D2M30_RS09930	COG1876	peptidase activity
D2M30_RS09950	COG0671	phosphoesterase, PA-phosphatase related
D2M30_RS09965	COG0346	lactoylglutathione lyase activity
D2M30_RS09980	COG1509	lysine 2,3-aminomutase activity
D2M30_RS09985	COG0456	acetyltransferase
D2M30_RS09990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D2M30_RS09995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D2M30_RS10000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D2M30_RS10005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D2M30_RS10015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D2M30_RS10025	COG0456	acetyltransferase
D2M30_RS10030	COG0463	Glycosyl transferase, family 2
D2M30_RS10045	COG4641	Protein conserved in bacteria
D2M30_RS10055	COG1086	Polysaccharide biosynthesis protein
D2M30_RS10085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D2M30_RS10090	COG1086	Polysaccharide biosynthesis protein
D2M30_RS10105	COG1846	Transcriptional regulator
D2M30_RS10110	COG4698	Protein conserved in bacteria
D2M30_RS10115	COG2755	lipolytic protein G-D-S-L family
D2M30_RS10120	COG1999	signal sequence binding
D2M30_RS10130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D2M30_RS10135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D2M30_RS10140	COG1272	protein, Hemolysin III
D2M30_RS10145	COG0204	Acyl-transferase
D2M30_RS10150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D2M30_RS10165	COG2136	Putative SAM-dependent methyltransferase
D2M30_RS10165	COG2521	methyltransferase
D2M30_RS10180	COG1413	lyase activity
D2M30_RS10185	COG1418	mRNA catabolic process
D2M30_RS10190	COG0386	Belongs to the glutathione peroxidase family
D2M30_RS10200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D2M30_RS10210	COG1278	Cold shock
D2M30_RS10230	COG0328	RNA-DNA hybrid ribonuclease activity
D2M30_RS10235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D2M30_RS10240	COG0328	RNA-DNA hybrid ribonuclease activity
D2M30_RS10250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D2M30_RS10265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D2M30_RS10275	COG1755	Isoprenylcysteine carboxyl methyltransferase
D2M30_RS10280	COG3424	synthase
D2M30_RS10310	COG3331	DNA recombination
D2M30_RS10365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D2M30_RS10395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D2M30_RS10435	COG0756	dUTP diphosphatase activity
D2M30_RS10445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS10480	COG1372	Participates in initiation and elongation during chromosome replication
D2M30_RS10480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D2M30_RS10485	COG1780	Probably involved in ribonucleotide reductase function
D2M30_RS10540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D2M30_RS10550	COG3584	3D domain protein
D2M30_RS10555	COG0587	DNA-directed DNA polymerase activity
D2M30_RS10560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D2M30_RS10565	COG0358	DNA primase activity
D2M30_RS10570	COG0305	Participates in initiation and elongation during chromosome replication
D2M30_RS10580	COG2887	Belongs to the helicase family. UvrD subfamily
D2M30_RS10615	COG3420	alginic acid biosynthetic process
D2M30_RS10615	COG5434	Belongs to the glycosyl hydrolase 28 family
D2M30_RS10620	COG4195	phage-related replication protein
D2M30_RS10645	COG2135	peptidase activity
D2M30_RS10745	COG3655	Transcriptional regulator
D2M30_RS10840	COG3655	Transcriptional regulator
D2M30_RS10960	COG0776	regulation of translation
D2M30_RS11080	COG0582	viral genome integration into host DNA
D2M30_RS11170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D2M30_RS11210	COG5444	nuclease activity
D2M30_RS11220	COG4282	regulation of fungal-type cell wall biogenesis
D2M30_RS11225	COG1525	nuclease
D2M30_RS11230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D2M30_RS11245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D2M30_RS11250	COG1199	ATP-dependent helicase activity
D2M30_RS11265	COG0116	Belongs to the methyltransferase superfamily
D2M30_RS11295	COG3359	exonuclease
D2M30_RS11300	COG1205	dead DEAH box helicase
D2M30_RS11300	COG1111	helicase
D2M30_RS11305	COG2190	(PTS) system
D2M30_RS11310	COG0071	Belongs to the small heat shock protein (HSP20) family
D2M30_RS11350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D2M30_RS11350	COG4499	WXG100 protein secretion system (Wss), protein YukC
D2M30_RS11360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D2M30_RS11365	COG3935	DnaD domain protein
D2M30_RS11375	COG0436	Aminotransferase
D2M30_RS11380	COG5353	protein conserved in bacteria
D2M30_RS11390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D2M30_RS11390	COG1199	ATP-dependent helicase activity
D2M30_RS11420	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS11425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D2M30_RS11440	COG1694	Mazg nucleotide pyrophosphohydrolase
D2M30_RS11445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS11450	COG2140	Oxalate decarboxylase
D2M30_RS11460	COG4347	Protein of unknown function (DUF1405)
D2M30_RS11465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D2M30_RS11465	COG2010	Cytochrome c
D2M30_RS11470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D2M30_RS11475	COG0723	plastoquinol--plastocyanin reductase activity
D2M30_RS11490	COG0457	Tetratricopeptide repeat
D2M30_RS11500	COG0287	Prephenate dehydrogenase
D2M30_RS11535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D2M30_RS11540	COG4401	Chorismate mutase type I
D2M30_RS11555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D2M30_RS11560	COG0105	UTP biosynthetic process
D2M30_RS11565	COG0142	geranyltranstransferase activity
D2M30_RS11575	COG0142	geranyltranstransferase activity
D2M30_RS11590	COG0776	regulation of translation
D2M30_RS11595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D2M30_RS11635	COG0539	negative regulation of cytoplasmic translation
D2M30_RS11645	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D2M30_RS11650	COG2959	enzyme of heme biosynthesis
D2M30_RS11655	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS11655	COG3773	Cell wall hydrolase
D2M30_RS11660	COG2339	peptidase activity
D2M30_RS11665	COG0492	ferredoxin-NADP+ reductase activity
D2M30_RS11670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D2M30_RS11675	COG4862	establishment of competence for transformation
D2M30_RS11680	COG1408	metallophosphoesterase
D2M30_RS11690	COG1388	LysM domain
D2M30_RS11695	COG1266	CAAX protease self-immunity
D2M30_RS11700	COG0514	ATP-dependent DNA helicase (RecQ)
D2M30_RS11705	COG4955	Helix-turn-helix domain
D2M30_RS11710	COG1141	Ferredoxin
D2M30_RS11715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D2M30_RS11720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D2M30_RS11730	COG1595	DNA-templated transcription, initiation
D2M30_RS11735	COG5002	protein histidine kinase activity
D2M30_RS11740	COG0745	RESPONSE REGULATOR receiver
D2M30_RS11745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D2M30_RS11750	COG1333	cytochrome c biogenesis protein
D2M30_RS11755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS11760	COG1187	pseudouridine synthase activity
D2M30_RS11765	COG0700	Nucleoside recognition
D2M30_RS11770	COG2715	membrane protein required for spore maturation
D2M30_RS11775	COG1686	Belongs to the peptidase S11 family
D2M30_RS11800	COG1547	Domain of unknown function (DUF309)
D2M30_RS11810	COG0456	acetyltransferase
D2M30_RS11815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D2M30_RS11825	COG0307	riboflavin synthase, alpha
D2M30_RS11830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D2M30_RS11830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D2M30_RS11840	COG0681	Belongs to the peptidase S26 family
D2M30_RS11850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D2M30_RS11855	COG4086	secreted protein
D2M30_RS11860	COG0019	diaminopimelate decarboxylase activity
D2M30_RS11865	COG0697	spore germination
D2M30_RS11880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D2M30_RS11900	COG1191	sigma factor activity
D2M30_RS11910	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS11915	COG1686	Belongs to the peptidase S11 family
D2M30_RS11920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D2M30_RS11925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D2M30_RS11930	COG4974	Belongs to the 'phage' integrase family
D2M30_RS11940	COG0735	belongs to the Fur family
D2M30_RS11945	COG1300	Membrane
D2M30_RS11960	COG0281	malic enzyme
D2M30_RS11965	COG1757	Na H antiporter
D2M30_RS11970	COG1027	Aspartate ammonia-lyase
D2M30_RS11975	COG0252	asparaginase activity
D2M30_RS11980	COG1396	sequence-specific DNA binding
D2M30_RS11985	COG1379	DNA repair
D2M30_RS11990	COG0494	nUDIX hydrolase
D2M30_RS12000	COG0667	Aldo Keto reductase
D2M30_RS12010	COG1073	alpha beta
D2M30_RS12020	COG4918	Iron-sulphur cluster biosynthesis
D2M30_RS12025	COG0456	acetyltransferase
D2M30_RS12025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D2M30_RS12030	COG0456	acetyltransferase
D2M30_RS12035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D2M30_RS12050	COG0628	permease
D2M30_RS12065	COG3048	D-serine ammonia-lyase activity
D2M30_RS12070	COG0300	oxidoreductase activity
D2M30_RS12075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS12080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D2M30_RS12085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D2M30_RS12085	COG2070	2-Nitropropane dioxygenase
D2M30_RS12090	COG0250	Participates in transcription elongation, termination and antitermination
D2M30_RS12115	COG0596	Alpha beta hydrolase
D2M30_RS12130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D2M30_RS12135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D2M30_RS12150	COG0706	membrane insertase activity
D2M30_RS12155	COG2195	Cleaves the N-terminal amino acid of tripeptides
D2M30_RS12160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D2M30_RS12165	COG0346	lactoylglutathione lyase activity
D2M30_RS12170	COG1376	ErfK ybiS ycfS ynhG family protein
D2M30_RS12175	COG4129	membrane
D2M30_RS12180	COG1126	abc transporter atp-binding protein
D2M30_RS12185	COG0765	amino acid transport
D2M30_RS12190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS12200	COG1597	lipid kinase activity
D2M30_RS12205	COG0508	dehydrogenase complex catalyzes the overall conversion of
D2M30_RS12210	COG0022	dehydrogenase e1 component
D2M30_RS12215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D2M30_RS12220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D2M30_RS12225	COG3426	butyrate kinase activity
D2M30_RS12230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D2M30_RS12235	COG0280	phosphate acetyltransferase
D2M30_RS12240	COG3290	protein histidine kinase activity
D2M30_RS12240	COG3829	transcription factor binding
D2M30_RS12250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D2M30_RS12255	COG2079	MmgE PrpD family protein
D2M30_RS12260	COG0372	Belongs to the citrate synthase family
D2M30_RS12265	COG1960	acyl-CoA dehydrogenase activity
D2M30_RS12270	COG1250	3-hydroxyacyl-CoA dehydrogenase
D2M30_RS12275	COG0183	Belongs to the thiolase family
D2M30_RS12280	COG0584	glycerophosphoryl diester phosphodiesterase
D2M30_RS12285	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS12320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D2M30_RS12325	COG0745	RESPONSE REGULATOR receiver
D2M30_RS12330	COG0750	zinc metalloprotease
D2M30_RS12335	COG0497	DNA recombination
D2M30_RS12345	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D2M30_RS12355	COG0142	geranyltranstransferase activity
D2M30_RS12365	COG1570	exodeoxyribonuclease VII activity
D2M30_RS12380	COG1302	Protein conserved in bacteria
D2M30_RS12385	COG0439	Biotin carboxylase
D2M30_RS12390	COG0511	ligase activity, forming carbon-carbon bonds
D2M30_RS12430	COG3854	ATPases associated with a variety of cellular activities
D2M30_RS12445	COG0006	proline dipeptidase activity
D2M30_RS12455	COG3872	metal-dependent enzyme
D2M30_RS12465	COG1752	Esterase of the alpha-beta hydrolase superfamily
D2M30_RS12480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D2M30_RS12500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D2M30_RS12515	COG1396	sequence-specific DNA binding
D2M30_RS12525	COG0681	Belongs to the peptidase S26 family
D2M30_RS12550	COG4940	Competence protein ComGF
D2M30_RS12560	COG4970	Tfp pilus assembly protein FimT
D2M30_RS12565	COG4537	Required for transformation and DNA binding
D2M30_RS12570	COG1459	type II secretion system
D2M30_RS12575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D2M30_RS12585	COG1253	flavin adenine dinucleotide binding
D2M30_RS12590	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS12600	COG1393	Belongs to the ArsC family
D2M30_RS12610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS12620	COG0011	TIGRFAM Protein of
D2M30_RS12630	COG2866	Carboxypeptidase
D2M30_RS12635	COG1940	carbohydrate kinase activity
D2M30_RS12640	COG4483	Protein conserved in bacteria
D2M30_RS12645	COG1757	Na H antiporter
D2M30_RS12655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D2M30_RS12670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D2M30_RS12675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D2M30_RS12680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D2M30_RS12685	COG0581	inorganic phosphate transmembrane transporter activity
D2M30_RS12690	COG0573	inorganic phosphate transmembrane transporter activity
D2M30_RS12695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D2M30_RS12700	COG0768	penicillin binding
D2M30_RS12705	COG0477	Major facilitator Superfamily
D2M30_RS12710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D2M30_RS12715	COG2839	Protein conserved in bacteria
D2M30_RS12720	COG5521	maltodextrose utilization protein MalA
D2M30_RS12725	COG1388	LysM domain
D2M30_RS12735	COG4709	membrane
D2M30_RS12740	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D2M30_RS12745	COG0735	belongs to the Fur family
D2M30_RS12765	COG0513	Belongs to the DEAD box helicase family
D2M30_RS12780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D2M30_RS12785	COG2384	SAM-dependent methyltransferase
D2M30_RS12790	COG2010	Cytochrome c
D2M30_RS12795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D2M30_RS12800	COG0358	DNA primase activity
D2M30_RS12815	COG0517	IMP dehydrogenase activity
D2M30_RS12820	COG0751	glycine-tRNA ligase activity
D2M30_RS12840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D2M30_RS12845	COG0295	cytidine deaminase activity
D2M30_RS12850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D2M30_RS12860	COG1480	7TM receptor with intracellular HD hydrolase
D2M30_RS12865	COG1702	phosphate starvation-inducible protein PhoH
D2M30_RS12870	COG0561	phosphatase activity
D2M30_RS12885	COG4864	UPF0365 protein
D2M30_RS12890	COG1030	water channel activity
D2M30_RS12895	COG1610	YqeY-like protein
D2M30_RS12905	COG1283	sodium-dependent phosphate transmembrane transporter activity
D2M30_RS12910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D2M30_RS12915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D2M30_RS12945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D2M30_RS12960	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS12975	COG1466	dna polymerase III delta subunit
D2M30_RS12990	COG2333	competence protein COMEC
D2M30_RS12990	COG0658	competence protein
D2M30_RS12995	COG2131	deaminase
D2M30_RS13000	COG1555	photosystem II stabilization
D2M30_RS13000	COG1596	polysaccharide export
D2M30_RS13005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D2M30_RS13010	COG2226	methyltransferase
D2M30_RS13015	COG0799	negative regulation of ribosome biogenesis
D2M30_RS13020	COG1713	HD superfamily hydrolase involved in NAD metabolism
D2M30_RS13030	COG1534	Rna-binding protein
D2M30_RS13035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D2M30_RS13040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D2M30_RS13045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D2M30_RS13055	COG2755	lipolytic protein G-D-S-L family
D2M30_RS13065	COG5632	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS13065	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS13070	COG0398	Pfam SNARE associated Golgi protein
D2M30_RS13135	COG0563	adenylate kinase activity
D2M30_RS13145	COG2814	Major facilitator Superfamily
D2M30_RS13160	COG2318	DinB family
D2M30_RS13165	COG0561	phosphatase activity
D2M30_RS13170	COG0561	phosphatase activity
D2M30_RS13180	COG1482	cell wall glycoprotein biosynthetic process
D2M30_RS13185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS13185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D2M30_RS13185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D2M30_RS13190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS13190	COG3711	transcriptional antiterminator
D2M30_RS13200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D2M30_RS13205	COG0583	DNA-binding transcription factor activity
D2M30_RS13210	COG2814	Major facilitator Superfamily
D2M30_RS13215	COG2124	cytochrome p450
D2M30_RS13215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D2M30_RS13220	COG1309	transcriptional regulator
D2M30_RS13225	COG2226	methyltransferase
D2M30_RS13235	COG2116	formate transmembrane transporter activity
D2M30_RS13240	COG5609	conserved protein (DUF2294)
D2M30_RS13245	COG3383	formate dehydrogenase (NAD+) activity
D2M30_RS13250	COG2427	Protein of unknown function (DUF1641)
D2M30_RS13260	COG0626	cystathionine gamma-synthase activity
D2M30_RS13265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D2M30_RS13290	COG0768	penicillin binding
D2M30_RS13325	COG5632	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS13325	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS13330	COG4824	toxin secretion phage lysis holin
D2M30_RS13350	COG5434	Belongs to the glycosyl hydrolase 28 family
D2M30_RS13355	COG1705	Flagellar rod assembly protein muramidase FlgJ
D2M30_RS13365	COG3953	SLT domain
D2M30_RS13365	COG5280	Phage tail tape measure protein TP901
D2M30_RS13455	COG0582	viral genome integration into host DNA
D2M30_RS13460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D2M30_RS13555	COG1396	sequence-specific DNA binding
D2M30_RS13580	COG0826	peptidase U32
D2M30_RS13585	COG0826	peptidase U32
D2M30_RS13590	COG4122	O-methyltransferase activity
D2M30_RS13595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D2M30_RS13610	COG4472	Bacterial protein of unknown function (DUF965)
D2M30_RS13620	COG0628	permease
D2M30_RS13625	COG1126	abc transporter atp-binding protein
D2M30_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS13635	COG0765	amino acid transport
D2M30_RS13640	COG0765	amino acid transport
D2M30_RS13655	COG3881	PFAM PRC-barrel domain
D2M30_RS13660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D2M30_RS13665	COG0457	Tetratricopeptide repeat
D2M30_RS13675	COG1104	cysteine desulfurase activity
D2M30_RS13680	COG1959	2 iron, 2 sulfur cluster binding
D2M30_RS13685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D2M30_RS13690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D2M30_RS13715	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS13715	COG3103	Sh3 type 3 domain protein
D2M30_RS13715	COG4991	sh3 domain protein
D2M30_RS13720	COG1490	D-aminoacyl-tRNA deacylase activity
D2M30_RS13725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D2M30_RS13735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D2M30_RS13735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D2M30_RS13740	COG5416	Lipopolysaccharide assembly protein A domain
D2M30_RS13745	COG0490	domain, Protein
D2M30_RS13750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D2M30_RS13750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D2M30_RS13760	COG2244	polysaccharide biosynthetic process
D2M30_RS13765	COG2323	membrane
D2M30_RS13775	COG1862	Preprotein translocase
D2M30_RS13815	COG1388	LysM domain
D2M30_RS13825	COG0157	Belongs to the NadC ModD family
D2M30_RS13830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D2M30_RS13835	COG1104	cysteine desulfurase activity
D2M30_RS13840	COG1827	regulation of RNA biosynthetic process
D2M30_RS13845	COG0077	Prephenate dehydratase
D2M30_RS13860	COG3290	protein histidine kinase activity
D2M30_RS13865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D2M30_RS13870	COG2868	ribosomal protein
D2M30_RS13880	COG1994	Peptidase M50
D2M30_RS13885	COG0739	heme binding
D2M30_RS13890	COG2894	cell division
D2M30_RS13895	COG0850	regulation of cytokinetic process
D2M30_RS13900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D2M30_RS13910	COG1077	Cell shape determining protein MreB Mrl
D2M30_RS13930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D2M30_RS13935	COG0285	dihydrofolate synthase activity
D2M30_RS13940	COG0525	valine-tRNA ligase activity
D2M30_RS13950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D2M30_RS13955	COG1388	LysM domain
D2M30_RS13965	COG0113	porphobilinogen synthase activity
D2M30_RS13970	COG1587	Uroporphyrinogen-III synthase
D2M30_RS13980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D2M30_RS14000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D2M30_RS14005	COG1067	ATP-dependent peptidase activity
D2M30_RS14005	COG0470	DNA polymerase III
D2M30_RS14020	COG0457	Tetratricopeptide repeat
D2M30_RS14020	COG1477	protein flavinylation
D2M30_RS14035	COG0473	3-isopropylmalate dehydrogenase activity
D2M30_RS14050	COG0440	acetolactate synthase activity
D2M30_RS14055	COG0028	Belongs to the TPP enzyme family
D2M30_RS14080	COG0622	Phosphoesterase
D2M30_RS14085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D2M30_RS14095	COG5401	PFAM Sporulation and spore germination
D2M30_RS14105	COG1846	Transcriptional regulator
D2M30_RS14110	COG2197	response regulator
D2M30_RS14115	COG0824	Thioesterase
D2M30_RS14120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D2M30_RS14125	COG1053	succinate dehydrogenase
D2M30_RS14130	COG2009	succinate dehydrogenase
D2M30_RS14135	COG1719	4-vinyl reductase, 4VR
D2M30_RS14140	COG0527	aspartate kinase activity
D2M30_RS14150	COG3118	belongs to the thioredoxin family
D2M30_RS14155	COG3534	alpha-L-arabinofuranosidase
D2M30_RS14160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D2M30_RS14165	COG2086	electron transfer activity
D2M30_RS14170	COG1024	Enoyl-CoA hydratase
D2M30_RS14175	COG1309	transcriptional regulator
D2M30_RS14180	COG0318	PFAM AMP-dependent synthetase and ligase
D2M30_RS14190	COG3766	membrane
D2M30_RS14200	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D2M30_RS14200	COG1796	DNA polymerase
D2M30_RS14205	COG1286	toxin biosynthetic process
D2M30_RS14220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D2M30_RS14220	COG0072	phenylalanine-tRNA ligase activity
D2M30_RS14225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D2M30_RS14230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D2M30_RS14240	COG3835	regulator
D2M30_RS14250	COG0247	lactate metabolic process
D2M30_RS14255	COG1966	Carbon starvation protein
D2M30_RS14260	COG3534	alpha-L-arabinofuranosidase
D2M30_RS14265	COG0395	ABC-type sugar transport system, permease component
D2M30_RS14270	COG1175	transmembrane transport
D2M30_RS14275	COG1653	transport
D2M30_RS14285	COG0647	UMP catabolic process
D2M30_RS14290	COG0235	Class ii aldolase
D2M30_RS14295	COG1069	ribulokinase activity
D2M30_RS14300	COG2160	L-arabinose isomerase activity
D2M30_RS14305	COG3507	Belongs to the glycosyl hydrolase 43 family
D2M30_RS14310	COG1363	Peptidase, m42
D2M30_RS14320	COG3326	Membrane
D2M30_RS14325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D2M30_RS14330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D2M30_RS14335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D2M30_RS14340	COG1346	cytolysis
D2M30_RS14345	COG1380	Effector of murein hydrolase LrgA
D2M30_RS14350	COG3279	Response regulator of the LytR AlgR family
D2M30_RS14355	COG3275	phosphorelay sensor kinase activity
D2M30_RS14360	COG1011	Hydrolase
D2M30_RS14375	COG0398	Pfam SNARE associated Golgi protein
D2M30_RS14380	COG1484	DNA-dependent DNA replication
D2M30_RS14385	COG3611	Membrane attachment protein
D2M30_RS14400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D2M30_RS14405	COG1733	regulation of RNA biosynthetic process
D2M30_RS14410	COG2814	Major facilitator Superfamily
D2M30_RS14415	COG0656	L-ascorbic acid biosynthetic process
D2M30_RS14420	COG0237	dephospho-CoA kinase activity
D2M30_RS14425	COG1971	Probably functions as a manganese efflux pump
D2M30_RS14430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D2M30_RS14435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D2M30_RS14435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D2M30_RS14440	COG5002	protein histidine kinase activity
D2M30_RS14445	COG0745	RESPONSE REGULATOR receiver
D2M30_RS14455	COG0538	isocitrate dehydrogenase activity
D2M30_RS14460	COG0372	Belongs to the citrate synthase family
D2M30_RS14470	COG0628	permease
D2M30_RS14475	COG3030	protein affecting phage T7 exclusion by the F plasmid
D2M30_RS14480	COG0469	pyruvate kinase activity
D2M30_RS14500	COG0281	malic enzyme
D2M30_RS14505	COG0587	DNA-directed DNA polymerase activity
D2M30_RS14525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D2M30_RS14535	COG4109	DRTGG domain
D2M30_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS14560	COG0521	Mo-molybdopterin cofactor biosynthetic process
D2M30_RS14570	COG0827	DNA restriction-modification system
D2M30_RS14575	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D2M30_RS14580	COG3874	Sporulation protein YtfJ
D2M30_RS14590	COG1714	RDD family
D2M30_RS14595	COG0616	signal peptide processing
D2M30_RS14600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D2M30_RS14605	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D2M30_RS14610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D2M30_RS14625	COG1104	cysteine desulfurase activity
D2M30_RS14630	COG1114	Component of the transport system for branched-chain amino acids
D2M30_RS14640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D2M30_RS14645	COG1309	transcriptional regulator
D2M30_RS14650	COG1956	GAF domain-containing protein
D2M30_RS14655	COG2199	diguanylate cyclase activity
D2M30_RS14655	COG2203	Gaf domain
D2M30_RS14670	COG1017	nitric oxide dioxygenase activity
D2M30_RS14670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D2M30_RS14695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D2M30_RS14700	COG1378	Sugar-specific transcriptional regulator TrmB
D2M30_RS14705	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D2M30_RS14720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D2M30_RS14725	COG0454	-acetyltransferase
D2M30_RS14730	COG0517	IMP dehydrogenase activity
D2M30_RS14735	COG0123	including yeast histone deacetylase and acetoin utilization protein
D2M30_RS14740	COG1360	Flagellar Motor Protein
D2M30_RS14745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D2M30_RS14750	COG1609	Transcriptional regulator
D2M30_RS14755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D2M30_RS14755	COG1605	Chorismate mutase
D2M30_RS14760	COG3118	belongs to the thioredoxin family
D2M30_RS14765	COG4980	gas vesicle protein
D2M30_RS14770	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D2M30_RS14780	COG1674	ftsk spoiiie
D2M30_RS14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D2M30_RS14795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS14805	COG1363	Peptidase, m42
D2M30_RS14810	COG5584	Small secreted protein
D2M30_RS14815	COG0281	malic enzyme
D2M30_RS14820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D2M30_RS14835	COG0510	thiamine kinase activity
D2M30_RS14840	COG1597	lipid kinase activity
D2M30_RS14850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D2M30_RS14855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D2M30_RS14860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D2M30_RS14865	COG2252	PERMEase
D2M30_RS14870	COG4473	ABC transporter
D2M30_RS14875	COG1131	(ABC) transporter
D2M30_RS14880	COG1349	DNA-binding transcription factor activity
D2M30_RS14885	COG1187	pseudouridine synthase activity
D2M30_RS14890	COG2244	polysaccharide biosynthetic process
D2M30_RS14895	COG2081	HI0933 family
D2M30_RS14900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D2M30_RS14910	COG1609	Transcriptional regulator
D2M30_RS14915	COG1653	transport
D2M30_RS14920	COG1175	transmembrane transport
D2M30_RS14925	COG0395	ABC-type sugar transport system, permease component
D2M30_RS14930	COG1486	melibiose metabolic process
D2M30_RS14940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D2M30_RS14955	COG1366	Belongs to the anti-sigma-factor antagonist family
D2M30_RS14955	COG2202	Pas domain
D2M30_RS14960	COG2814	Major facilitator Superfamily
D2M30_RS14965	COG5522	Integral membrane protein (intg_mem_TP0381)
D2M30_RS14970	COG0577	efflux transmembrane transporter activity
D2M30_RS14975	COG1136	(ABC) transporter
D2M30_RS14980	COG2205	protein histidine kinase activity
D2M30_RS14985	COG0745	RESPONSE REGULATOR receiver
D2M30_RS14990	COG0577	efflux transmembrane transporter activity
D2M30_RS14995	COG1136	(ABC) transporter
D2M30_RS15015	COG1131	(ABC) transporter
D2M30_RS15020	COG1725	Transcriptional regulator
D2M30_RS15030	COG1242	4 iron, 4 sulfur cluster binding
D2M30_RS15035	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D2M30_RS15050	COG2267	carboxylic ester hydrolase activity
D2M30_RS15055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D2M30_RS15060	COG1113	amino acid transport
D2M30_RS15065	COG0367	asparagine synthase
D2M30_RS15085	COG1506	peptidase
D2M30_RS15090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D2M30_RS15095	COG1116	anion transmembrane transporter activity
D2M30_RS15100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D2M30_RS15105	COG0494	nUDIX hydrolase
D2M30_RS15110	COG4824	toxin secretion phage lysis holin
D2M30_RS15115	COG0783	Belongs to the Dps family
D2M30_RS15140	COG0288	reversible hydration of carbon dioxide
D2M30_RS15150	COG1271	oxidase subunit
D2M30_RS15155	COG1294	oxidase, subunit
D2M30_RS15165	COG4948	Mandelate Racemase Muconate Lactonizing
D2M30_RS15175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D2M30_RS15180	COG0596	Alpha beta hydrolase
D2M30_RS15190	COG1169	isochorismate synthase
D2M30_RS15195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D2M30_RS15200	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D2M30_RS15325	COG3859	Proton-coupled thiamine transporter YuaJ
D2M30_RS15330	COG2268	Band 7 protein
D2M30_RS15335	COG1585	Membrane protein implicated in regulation of membrane protease activity
D2M30_RS15340	COG2318	DinB family
D2M30_RS15350	COG1454	alcohol dehydrogenase
D2M30_RS15355	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS15360	COG1510	regulation of RNA biosynthetic process
D2M30_RS15370	COG0569	domain protein
D2M30_RS15375	COG1705	Flagellar rod assembly protein muramidase FlgJ
D2M30_RS15380	COG1017	nitric oxide dioxygenase activity
D2M30_RS15380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D2M30_RS15405	COG0628	permease
D2M30_RS15410	COG0673	inositol 2-dehydrogenase activity
D2M30_RS15415	COG0693	protein deglycase activity
D2M30_RS15420	COG0840	transmembrane signaling receptor activity
D2M30_RS15425	COG0840	transmembrane signaling receptor activity
D2M30_RS15430	COG0840	transmembrane signaling receptor activity
D2M30_RS15435	COG0840	transmembrane signaling receptor activity
D2M30_RS15450	COG2070	2-Nitropropane dioxygenase
D2M30_RS15455	COG0432	Pfam Uncharacterised protein family UPF0047
D2M30_RS15465	COG1253	flavin adenine dinucleotide binding
D2M30_RS15470	COG2738	Putative neutral zinc metallopeptidase
D2M30_RS15485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D2M30_RS15510	COG1335	isochorismatase
D2M30_RS15515	COG1979	alcohol dehydrogenase
D2M30_RS15520	COG1979	alcohol dehydrogenase
D2M30_RS15525	COG2155	Conserved Protein
D2M30_RS15530	COG1098	S1 RNA binding domain
D2M30_RS15535	COG0436	Aminotransferase
D2M30_RS15540	COG1522	sequence-specific DNA binding
D2M30_RS15545	COG2267	carboxylic ester hydrolase activity
D2M30_RS15555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D2M30_RS15560	COG2205	protein histidine kinase activity
D2M30_RS15570	COG5018	Exonuclease
D2M30_RS15575	COG2814	Major facilitator Superfamily
D2M30_RS15580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D2M30_RS15585	COG3011	Protein conserved in bacteria
D2M30_RS15595	COG3290	protein histidine kinase activity
D2M30_RS15600	COG4565	transcriptional regulatory protein
D2M30_RS15605	COG1744	ABC transporter substrate-binding protein PnrA-like
D2M30_RS15610	COG3845	ABC transporter
D2M30_RS15615	COG4603	Belongs to the binding-protein-dependent transport system permease family
D2M30_RS15620	COG1079	Belongs to the binding-protein-dependent transport system permease family
D2M30_RS15630	COG2111	Na H antiporter
D2M30_RS15630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D2M30_RS15635	COG2111	Na H antiporter
D2M30_RS15640	COG1006	Multisubunit Na H antiporter MnhC subunit
D2M30_RS15645	COG0651	ATP synthesis coupled electron transport
D2M30_RS15650	COG1863	multisubunit Na H antiporter MnhE subunit
D2M30_RS15655	COG2212	antiporter activity
D2M30_RS15660	COG1320	monovalent cation:proton antiporter activity
D2M30_RS15665	COG2050	protein possibly involved in aromatic compounds catabolism
D2M30_RS15670	COG2197	response regulator
D2M30_RS15675	COG4585	Histidine kinase
D2M30_RS15685	COG0142	geranyltranstransferase activity
D2M30_RS15705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D2M30_RS15710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D2M30_RS15715	COG1335	isochorismatase
D2M30_RS15720	COG5506	Protein of unknown function (DUF1694)
D2M30_RS15735	COG0628	permease
D2M30_RS15745	COG1418	mRNA catabolic process
D2M30_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS15760	COG1511	domain protein
D2M30_RS15765	COG1674	ftsk spoiiie
D2M30_RS15765	COG0433	COG0433 Predicted ATPase
D2M30_RS15770	COG4499	WXG100 protein secretion system (Wss), protein YukC
D2M30_RS15775	COG5417	Belongs to the EsaB family
D2M30_RS15780	COG4842	Belongs to the WXG100 family
D2M30_RS15785	COG2508	Transcriptional regulator
D2M30_RS15785	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D2M30_RS15790	COG0686	Belongs to the AlaDH PNT family
D2M30_RS15795	COG5634	Uncharacterized conserved protein (DUF2278)
D2M30_RS15800	COG3251	PFAM MbtH domain protein
D2M30_RS15805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D2M30_RS15810	COG1535	isochorismatase
D2M30_RS15810	COG3433	isochorismatase activity
D2M30_RS15815	COG1021	2,3-dihydroxybenzoate-AMP ligase
D2M30_RS15820	COG1169	isochorismate synthase
D2M30_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS15830	COG2819	hydrolase of the alpha beta superfamily
D2M30_RS15835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D2M30_RS15840	COG1268	BioY protein
D2M30_RS15845	COG2056	Na+-H+ antiporter family
D2M30_RS15855	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D2M30_RS15860	COG3584	3D domain protein
D2M30_RS15875	COG1252	NADH dehydrogenase
D2M30_RS15900	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D2M30_RS15905	COG0316	Belongs to the HesB IscA family
D2M30_RS15915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D2M30_RS15925	COG1252	NADH dehydrogenase
D2M30_RS15930	COG4837	Protein of unknown function (DUF1462)
D2M30_RS15935	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D2M30_RS15940	COG1506	peptidase
D2M30_RS15940	COG0823	Involved in the tonB-independent uptake of proteins
D2M30_RS15940	COG4946	Tricorn protease homolog
D2M30_RS15950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D2M30_RS15955	COG0460	homoserine dehydrogenase
D2M30_RS15960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D2M30_RS15965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D2M30_RS15970	COG0647	UMP catabolic process
D2M30_RS15975	COG2445	Protein of unknown function DUF86
D2M30_RS15980	COG4470	Protein conserved in bacteria
D2M30_RS15995	COG0739	heme binding
D2M30_RS16005	COG0737	Belongs to the 5'-nucleotidase family
D2M30_RS16010	COG0730	response to heat
D2M30_RS16015	COG1801	Protein of unknown function DUF72
D2M30_RS16030	COG2508	Transcriptional regulator
D2M30_RS16045	COG2814	Major facilitator Superfamily
D2M30_RS16050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D2M30_RS16055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D2M30_RS16060	COG2356	endonuclease I
D2M30_RS16080	COG0395	ABC-type sugar transport system, permease component
D2M30_RS16085	COG1175	transmembrane transport
D2M30_RS16090	COG1653	transport
D2M30_RS16095	COG2222	sugar isomerase
D2M30_RS16100	COG0789	Transcriptional regulator
D2M30_RS16125	COG0322	excinuclease ABC activity
D2M30_RS16130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D2M30_RS16145	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS16150	COG0719	Fe-S assembly protein
D2M30_RS16155	COG0822	iron-sulfur transferase activity
D2M30_RS16160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D2M30_RS16165	COG0719	Fe-S assembly protein
D2M30_RS16170	COG0396	ATPase activity
D2M30_RS16185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D2M30_RS16190	COG1464	Belongs to the NlpA lipoprotein family
D2M30_RS16195	COG2011	ABC-type metal ion transport system permease component
D2M30_RS16200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D2M30_RS16210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D2M30_RS16215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D2M30_RS16230	COG1393	Belongs to the ArsC family
D2M30_RS16235	COG1960	acyl-CoA dehydrogenase activity
D2M30_RS16240	COG0183	Belongs to the thiolase family
D2M30_RS16245	COG1024	Enoyl-CoA hydratase
D2M30_RS16245	COG1250	3-hydroxyacyl-CoA dehydrogenase
D2M30_RS16265	COG5577	PFAM Coat F domain
D2M30_RS16270	COG1846	Transcriptional regulator
D2M30_RS16275	COG0477	Major facilitator Superfamily
D2M30_RS16280	COG1942	4-Oxalocrotonate Tautomerase
D2M30_RS16290	COG0583	DNA-binding transcription factor activity
D2M30_RS16300	COG1120	ATPase activity
D2M30_RS16315	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS16320	COG0783	Belongs to the Dps family
D2M30_RS16325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D2M30_RS16330	COG0745	RESPONSE REGULATOR receiver
D2M30_RS16335	COG2205	protein histidine kinase activity
D2M30_RS16335	COG2770	Histidine kinase
D2M30_RS16345	COG1309	transcriptional regulator
D2M30_RS16350	COG0114	fumarate hydratase activity
D2M30_RS16360	COG0697	spore germination
D2M30_RS16365	COG0814	amino acid
D2M30_RS16375	COG2197	response regulator
D2M30_RS16380	COG4585	Histidine kinase
D2M30_RS16385	COG4758	membrane
D2M30_RS16390	COG3595	metallopeptidase activity
D2M30_RS16395	COG1842	Phage shock protein A
D2M30_RS16400	COG4758	membrane
D2M30_RS16405	COG2814	Major facilitator Superfamily
D2M30_RS16410	COG2096	Adenosyltransferase
D2M30_RS16415	COG1120	ATPase activity
D2M30_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS16425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D2M30_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS16435	COG3386	PFAM SMP-30 Gluconolaconase
D2M30_RS16440	COG2205	protein histidine kinase activity
D2M30_RS16445	COG0745	RESPONSE REGULATOR receiver
D2M30_RS16455	COG1191	sigma factor activity
D2M30_RS16465	COG2140	Oxalate decarboxylase
D2M30_RS16475	COG1120	ATPase activity
D2M30_RS16480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS16485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS16490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D2M30_RS16495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D2M30_RS16500	COG0531	amino acid
D2M30_RS16515	COG1988	membrane-bound metal-dependent
D2M30_RS16520	COG1368	sulfuric ester hydrolase activity
D2M30_RS16525	COG1910	domain protein
D2M30_RS16530	COG0725	ABC transporter, periplasmic molybdate-binding protein
D2M30_RS16535	COG4149	molybdate abc transporter
D2M30_RS16540	COG2197	response regulator
D2M30_RS16550	COG1131	(ABC) transporter
D2M30_RS16560	COG0842	Transport permease protein
D2M30_RS16565	COG0656	L-ascorbic acid biosynthetic process
D2M30_RS16585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D2M30_RS16590	COG3973	AAA domain
D2M30_RS16595	COG2860	membrane
D2M30_RS16605	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D2M30_RS16610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D2M30_RS16615	COG2217	Heavy metal translocating P-type atpase
D2M30_RS16620	COG2217	Heavy metal translocating P-type atpase
D2M30_RS16625	COG2608	mercury ion transmembrane transporter activity
D2M30_RS16630	COG1937	Protein conserved in bacteria
D2M30_RS16635	COG0673	inositol 2-dehydrogenase activity
D2M30_RS16650	COG2814	Major facilitator Superfamily
D2M30_RS16665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS16670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D2M30_RS16675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS16680	COG1126	abc transporter atp-binding protein
D2M30_RS16685	COG0765	amino acid transport
D2M30_RS16690	COG0765	amino acid transport
D2M30_RS16695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS16700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D2M30_RS16705	COG0454	-acetyltransferase
D2M30_RS16710	COG0583	DNA-binding transcription factor activity
D2M30_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS16720	COG2732	(Barnase) inhibitor
D2M30_RS16735	COG0557	exoribonuclease II activity
D2M30_RS16740	COG1647	Serine aminopeptidase, S33
D2M30_RS16745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D2M30_RS16750	COG1476	TRANSCRIPTIONal
D2M30_RS16755	COG1396	sequence-specific DNA binding
D2M30_RS16760	COG1396	sequence-specific DNA binding
D2M30_RS16765	COG1733	regulation of RNA biosynthetic process
D2M30_RS16790	COG1131	(ABC) transporter
D2M30_RS16795	COG1174	glycine betaine transport
D2M30_RS16800	COG1732	Glycine betaine
D2M30_RS16805	COG1174	glycine betaine transport
D2M30_RS16810	COG1125	glycine betaine transport
D2M30_RS16810	COG0517	IMP dehydrogenase activity
D2M30_RS16815	COG1510	regulation of RNA biosynthetic process
D2M30_RS16820	COG1174	glycine betaine transport
D2M30_RS16825	COG1732	Glycine betaine
D2M30_RS16830	COG1174	glycine betaine transport
D2M30_RS16835	COG1125	glycine betaine transport
D2M30_RS16835	COG0517	IMP dehydrogenase activity
D2M30_RS16840	COG1510	regulation of RNA biosynthetic process
D2M30_RS16845	COG2095	MarC family integral membrane protein
D2M30_RS16850	COG3064	Membrane
D2M30_RS16855	COG4640	response to antibiotic
D2M30_RS16860	COG0456	acetyltransferase
D2M30_RS16875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D2M30_RS16895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D2M30_RS16900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D2M30_RS16910	COG2234	aminopeptidase activity
D2M30_RS16930	COG0126	phosphoglycerate kinase activity
D2M30_RS16940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D2M30_RS16945	COG2390	Transcriptional regulator
D2M30_RS16950	COG2814	Major facilitator Superfamily
D2M30_RS16955	COG1609	Transcriptional regulator
D2M30_RS16960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS16970	COG0583	DNA-binding transcription factor activity
D2M30_RS16975	COG0697	spore germination
D2M30_RS16980	COG1113	amino acid transport
D2M30_RS16985	COG1737	Transcriptional regulator
D2M30_RS16990	COG1070	Carbohydrate kinase
D2M30_RS17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D2M30_RS17020	COG2186	Transcriptional regulator
D2M30_RS17025	COG1620	l-lactate permease
D2M30_RS17030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D2M30_RS17040	COG5039	Polysaccharide pyruvyl transferase
D2M30_RS17045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D2M30_RS17050	COG0110	maltose O-acetyltransferase activity
D2M30_RS17055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D2M30_RS17060	COG2244	polysaccharide biosynthetic process
D2M30_RS17065	COG1216	Glycosyl transferase, family 2
D2M30_RS17070	COG5039	Polysaccharide pyruvyl transferase
D2M30_RS17075	COG1216	Glycosyl transferase, family 2
D2M30_RS17085	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS17090	COG1215	transferase activity, transferring glycosyl groups
D2M30_RS17095	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS17100	COG1086	Polysaccharide biosynthesis protein
D2M30_RS17105	COG0489	protein tyrosine kinase activity
D2M30_RS17110	COG3944	biosynthesis protein
D2M30_RS17115	COG1396	sequence-specific DNA binding
D2M30_RS17120	COG2272	Belongs to the type-B carboxylesterase lipase family
D2M30_RS17130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D2M30_RS17145	COG2364	Membrane
D2M30_RS17155	COG3479	Phenolic acid decarboxylase
D2M30_RS17195	COG2211	Major facilitator Superfamily
D2M30_RS17205	COG1609	Transcriptional regulator
D2M30_RS17215	COG0583	DNA-binding transcription factor activity
D2M30_RS17220	COG2828	Protein conserved in bacteria
D2M30_RS17225	COG2814	Major facilitator Superfamily
D2M30_RS17225	COG0477	Major facilitator Superfamily
D2M30_RS17235	COG1611	Belongs to the LOG family
D2M30_RS17240	COG1694	Mazg nucleotide pyrophosphohydrolase
D2M30_RS17245	COG0659	secondary active sulfate transmembrane transporter activity
D2M30_RS17250	COG0288	reversible hydration of carbon dioxide
D2M30_RS17260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D2M30_RS17265	COG4290	ribonuclease
D2M30_RS17270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D2M30_RS17275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS17285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D2M30_RS17295	COG1051	belongs to the nudix hydrolase family
D2M30_RS17300	COG0492	ferredoxin-NADP+ reductase activity
D2M30_RS17305	COG3883	PFAM NLP P60 protein
D2M30_RS17305	COG0791	NLP P60 protein
D2M30_RS17310	COG0457	Tetratricopeptide repeat
D2M30_RS17315	COG5002	protein histidine kinase activity
D2M30_RS17320	COG0745	RESPONSE REGULATOR receiver
D2M30_RS17325	COG1132	(ABC) transporter
D2M30_RS17330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D2M30_RS17330	COG0140	phosphoribosyl-ATP diphosphatase activity
D2M30_RS17355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D2M30_RS17370	COG4990	cell redox homeostasis
D2M30_RS17375	COG0110	maltose O-acetyltransferase activity
D2M30_RS17395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D2M30_RS17405	COG2188	Transcriptional regulator
D2M30_RS17410	COG1309	transcriptional regulator
D2M30_RS17415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D2M30_RS17420	COG1950	PFAM Membrane protein of
D2M30_RS17425	COG1983	PspC domain protein
D2M30_RS17430	COG3595	metallopeptidase activity
D2M30_RS17445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D2M30_RS17455	COG4897	Protein conserved in bacteria
D2M30_RS17460	COG0574	Belongs to the PEP-utilizing enzyme family
D2M30_RS17460	COG3848	Pyruvate phosphate dikinase
D2M30_RS17465	COG1309	transcriptional regulator
D2M30_RS17470	COG2814	Major facilitator Superfamily
D2M30_RS17480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D2M30_RS17490	COG0793	Belongs to the peptidase S41A family
D2M30_RS17490	COG3409	Peptidoglycan-binding domain 1 protein
D2M30_RS17495	COG3420	alginic acid biosynthetic process
D2M30_RS17500	COG2177	Part of the ABC transporter FtsEX involved in
D2M30_RS17505	COG2884	Cell division ATP-binding protein ftsE
D2M30_RS17510	COG2010	Cytochrome c
D2M30_RS17515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS17530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D2M30_RS17545	COG1516	flagellar protein fliS
D2M30_RS17550	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D2M30_RS17555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D2M30_RS17575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D2M30_RS17580	COG1256	bacterial-type flagellum assembly
D2M30_RS17580	COG4786	Flagellar basal body rod
D2M30_RS17585	COG3418	PFAM FlgN family protein
D2M30_RS17590	COG2747	anti-sigma28 factor FlgM
D2M30_RS17600	COG1040	competence protein
D2M30_RS17610	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D2M30_RS17615	COG1307	EDD domain protein, DegV family
D2M30_RS17620	COG2197	response regulator
D2M30_RS17625	COG4585	Histidine kinase
D2M30_RS17630	COG1739	Uncharacterized protein family UPF0029
D2M30_RS17635	COG1316	TRANSCRIPTIONal
D2M30_RS17640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D2M30_RS17645	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS17650	COG1215	transferase activity, transferring glycosyl groups
D2M30_RS17655	COG3206	protein involved in exopolysaccharide biosynthesis
D2M30_RS17660	COG3307	-O-antigen
D2M30_RS17665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D2M30_RS17670	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS17670	COG0297	glycogen (starch) synthase activity
D2M30_RS17675	COG2244	polysaccharide biosynthetic process
D2M30_RS17685	COG0860	N-Acetylmuramoyl-L-alanine amidase
D2M30_RS17685	COG2247	cell wall binding repeat
D2M30_RS17690	COG2247	cell wall binding repeat
D2M30_RS17690	COG2385	sporulation resulting in formation of a cellular spore
D2M30_RS17700	COG1316	TRANSCRIPTIONal
D2M30_RS17705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D2M30_RS17710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D2M30_RS17715	COG1134	teichoic acid transport
D2M30_RS17720	COG1682	transport, permease protein
D2M30_RS17725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D2M30_RS17730	COG0463	Glycosyl transferase, family 2
D2M30_RS17735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D2M30_RS17740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D2M30_RS17745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D2M30_RS17750	COG4193	domain, Protein
D2M30_RS17755	COG1482	cell wall glycoprotein biosynthetic process
D2M30_RS17760	COG0697	spore germination
D2M30_RS17765	COG0814	amino acid
D2M30_RS17775	COG1215	transferase activity, transferring glycosyl groups
D2M30_RS17780	COG2814	Major facilitator Superfamily
D2M30_RS17785	COG1316	TRANSCRIPTIONal
D2M30_RS17790	COG0561	phosphatase activity
D2M30_RS17795	COG2433	Pfam Transposase IS66
D2M30_RS17800	COG0791	NLP P60 protein
D2M30_RS17815	COG2843	Capsule synthesis protein
D2M30_RS17825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D2M30_RS17835	COG0697	spore germination
D2M30_RS17840	COG0814	amino acid
D2M30_RS17850	COG1609	Transcriptional regulator
D2M30_RS17855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D2M30_RS17865	COG1129	ABC transporter
D2M30_RS17870	COG1172	Belongs to the binding-protein-dependent transport system permease family
D2M30_RS17875	COG1879	ABC-type sugar transport system periplasmic component
D2M30_RS17880	COG3103	Sh3 type 3 domain protein
D2M30_RS17885	COG2249	NAD(P)H dehydrogenase (quinone) activity
D2M30_RS17890	COG3527	Alpha-acetolactate decarboxylase
D2M30_RS17895	COG0028	Belongs to the TPP enzyme family
D2M30_RS17900	COG0583	DNA-binding transcription factor activity
D2M30_RS17905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D2M30_RS17920	COG5337	Spore coat protein CotH
D2M30_RS17930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D2M30_RS17940	COG0405	Gamma-glutamyltransferase
D2M30_RS17945	COG1522	sequence-specific DNA binding
D2M30_RS17950	COG2059	Chromate
D2M30_RS17955	COG2059	Chromate
D2M30_RS17970	COG5444	nuclease activity
D2M30_RS17985	COG3878	Protein conserved in bacteria
D2M30_RS17990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D2M30_RS17995	COG4464	protein tyrosine phosphatase activity
D2M30_RS18000	COG0489	protein tyrosine kinase activity
D2M30_RS18005	COG3944	biosynthesis protein
D2M30_RS18020	COG4715	Zinc finger, swim domain protein
D2M30_RS18025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D2M30_RS18030	COG0561	phosphatase activity
D2M30_RS18035	COG1349	DNA-binding transcription factor activity
D2M30_RS18040	COG0629	single-stranded DNA binding
D2M30_RS18065	COG0457	Tetratricopeptide repeat
D2M30_RS18070	COG4786	Flagellar basal body rod
D2M30_RS18075	COG4786	Flagellar basal body rod
D2M30_RS18080	COG1077	Cell shape determining protein MreB Mrl
D2M30_RS18090	COG1846	Transcriptional regulator
D2M30_RS18095	COG2814	Major facilitator Superfamily
D2M30_RS18100	COG1953	Uracil, thiamine, allantoin
D2M30_RS18105	COG0477	Major facilitator Superfamily
D2M30_RS18110	COG1335	isochorismatase
D2M30_RS18115	COG0004	ammonium transporteR
D2M30_RS18120	COG0347	Belongs to the P(II) protein family
D2M30_RS18125	COG0772	Belongs to the SEDS family
D2M30_RS18130	COG0671	phosphoesterase, PA-phosphatase related
D2M30_RS18145	COG0739	heme binding
D2M30_RS18150	COG1247	-acetyltransferase
D2M30_RS18165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D2M30_RS18175	COG2910	NAD(P)H-binding
D2M30_RS18180	COG1959	2 iron, 2 sulfur cluster binding
D2M30_RS18195	COG0831	urea catabolic process
D2M30_RS18200	COG3237	CsbD-like
D2M30_RS18205	COG1994	Peptidase M50
D2M30_RS18210	COG0457	Tetratricopeptide repeat
D2M30_RS18220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D2M30_RS18225	COG2304	oxidoreductase activity
D2M30_RS18230	COG2304	oxidoreductase activity
D2M30_RS18235	COG2385	sporulation resulting in formation of a cellular spore
D2M30_RS18240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D2M30_RS18250	COG4836	Membrane
D2M30_RS18320	COG0698	ribose 5-phosphate isomerase
D2M30_RS18325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D2M30_RS18335	COG0009	L-threonylcarbamoyladenylate synthase
D2M30_RS18340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D2M30_RS18360	COG2890	protein-(glutamine-N5) methyltransferase activity
D2M30_RS18365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D2M30_RS18370	COG0346	lactoylglutathione lyase activity
D2M30_RS18375	COG0789	Transcriptional regulator
D2M30_RS18380	COG0679	Auxin Efflux Carrier
D2M30_RS18385	COG0281	malic enzyme
D2M30_RS18400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D2M30_RS18405	COG1494	fructose-1,6-bisphosphatase
D2M30_RS18410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D2M30_RS18420	COG0191	fructose-bisphosphate aldolase activity
D2M30_RS18425	COG2204	response regulator
D2M30_RS18430	COG4821	SIS domain
D2M30_RS18445	COG0247	lactate metabolic process
D2M30_RS18445	COG2181	nitrate reductase activity
D2M30_RS18450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D2M30_RS18465	COG1132	(ABC) transporter
D2M30_RS18475	COG2181	nitrate reductase activity
D2M30_RS18480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D2M30_RS18485	COG1140	nitrate reductase beta subunit
D2M30_RS18495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D2M30_RS18505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D2M30_RS18510	COG2223	nitrite transmembrane transporter activity
D2M30_RS18520	COG4506	Protein conserved in bacteria
D2M30_RS18530	COG3391	amine dehydrogenase activity
D2M30_RS18540	COG0457	Tetratricopeptide repeat
D2M30_RS18550	COG0010	Belongs to the arginase family
D2M30_RS18555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D2M30_RS18560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D2M30_RS18575	COG1994	Peptidase M50
D2M30_RS18580	COG1942	4-Oxalocrotonate Tautomerase
D2M30_RS18585	COG1846	Transcriptional regulator
D2M30_RS18595	COG0531	amino acid
D2M30_RS18600	COG3465	dGTPase activity
D2M30_RS18605	COG1078	dGTPase activity
D2M30_RS18620	COG1695	Transcriptional regulator
D2M30_RS18630	COG1131	(ABC) transporter
D2M30_RS18635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D2M30_RS18665	COG0583	DNA-binding transcription factor activity
D2M30_RS18670	COG2855	membrane
D2M30_RS18675	COG0280	phosphate acetyltransferase
D2M30_RS18685	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS18690	COG0436	Aminotransferase
D2M30_RS18700	COG0151	Belongs to the GarS family
D2M30_RS18710	COG1917	Cupin 2, conserved barrel domain protein
D2M30_RS18715	COG0077	Prephenate dehydratase
D2M30_RS18720	COG2814	Major facilitator Superfamily
D2M30_RS18725	COG2814	Major facilitator Superfamily
D2M30_RS18730	COG0833	amino acid
D2M30_RS18735	COG4187	Peptidase family M20/M25/M40
D2M30_RS18745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D2M30_RS18755	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D2M30_RS18760	COG1091	dTDP-4-dehydrorhamnose reductase activity
D2M30_RS18765	COG1088	dTDP-glucose 4,6-dehydratase activity
D2M30_RS18770	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D2M30_RS18775	COG3980	spore coat polysaccharide biosynthesis protein
D2M30_RS18780	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D2M30_RS18785	COG2089	acid synthase
D2M30_RS18790	COG0456	acetyltransferase
D2M30_RS18795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D2M30_RS18800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D2M30_RS18805	COG0463	Glycosyl transferase, family 2
D2M30_RS18815	COG2363	Small membrane protein
D2M30_RS18820	COG2233	PERMEase
D2M30_RS18835	COG1216	Glycosyl transferase, family 2
D2M30_RS18845	COG0351	phosphomethylpyrimidine kinase
D2M30_RS18855	COG1621	beta-fructofuranosidase activity
D2M30_RS18860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS18860	COG1263	PTS System
D2M30_RS18865	COG3711	transcriptional antiterminator
D2M30_RS18875	COG1404	Belongs to the peptidase S8 family
D2M30_RS18880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D2M30_RS18885	COG2378	regulation of single-species biofilm formation
D2M30_RS18905	COG0778	Nitroreductase
D2M30_RS18910	COG0772	Belongs to the SEDS family
D2M30_RS18915	COG0454	-acetyltransferase
D2M30_RS18935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D2M30_RS18940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D2M30_RS18945	COG2261	transglycosylase associated protein
D2M30_RS18950	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D2M30_RS18955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D2M30_RS18960	COG2246	polysaccharide biosynthetic process
D2M30_RS18965	COG1309	transcriptional regulator
D2M30_RS18985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D2M30_RS18990	COG2837	iron assimilation
D2M30_RS18995	COG2822	iron ion transport
D2M30_RS19000	COG0672	)-iron permease
D2M30_RS19015	COG0583	DNA-binding transcription factor activity
D2M30_RS19025	COG1346	cytolysis
D2M30_RS19030	COG4895	conserved protein (DUF2196)
D2M30_RS19035	COG0789	Transcriptional regulator
D2M30_RS19040	COG5504	Zn-dependent protease
D2M30_RS19055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D2M30_RS19060	COG0346	lactoylglutathione lyase activity
D2M30_RS19065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS19070	COG1404	Belongs to the peptidase S8 family
D2M30_RS19075	COG1442	glycosyl transferase family 8
D2M30_RS19080	COG2357	RelA SpoT domain protein
D2M30_RS19085	COG1575	Belongs to the MenA family. Type 1 subfamily
D2M30_RS19110	COG1696	Membrane protein involved in D-alanine export
D2M30_RS19120	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D2M30_RS19125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D2M30_RS19130	COG1486	melibiose metabolic process
D2M30_RS19135	COG1447	Phosphotransferase system cellobiose-specific component IIA
D2M30_RS19140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS19145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS19150	COG3711	transcriptional antiterminator
D2M30_RS19150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D2M30_RS19165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS19170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D2M30_RS19180	COG0640	Transcriptional regulator
D2M30_RS19185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D2M30_RS19190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS19195	COG1447	Phosphotransferase system cellobiose-specific component IIA
D2M30_RS19200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D2M30_RS19205	COG2723	6-phospho-beta-galactosidase activity
D2M30_RS19210	COG1940	carbohydrate kinase activity
D2M30_RS19215	COG1482	cell wall glycoprotein biosynthetic process
D2M30_RS19225	COG0753	catalase activity
D2M30_RS19230	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D2M30_RS19235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D2M30_RS19240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D2M30_RS19245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D2M30_RS19250	COG4988	ABC transporter
D2M30_RS19255	COG1294	oxidase, subunit
D2M30_RS19260	COG1271	oxidase subunit
D2M30_RS19265	COG3493	citrate carrier protein
D2M30_RS19270	COG0726	polysaccharide deacetylase
D2M30_RS19275	COG3842	ATPase activity
D2M30_RS19280	COG2508	Transcriptional regulator
D2M30_RS19285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS19295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D2M30_RS19305	COG4894	glucomannan catabolic process
D2M30_RS19310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D2M30_RS19315	COG0500	methyltransferase
D2M30_RS19320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D2M30_RS19335	COG0693	protein deglycase activity
D2M30_RS19335	COG0753	catalase activity
D2M30_RS19340	COG2851	Citrate transporter
D2M30_RS19345	COG2273	Hydrolase Family 16
D2M30_RS19350	COG3711	transcriptional antiterminator
D2M30_RS19355	COG2270	Major facilitator Superfamily
D2M30_RS19360	COG0513	Belongs to the DEAD box helicase family
D2M30_RS19445	COG3209	COG3209 Rhs family protein
D2M30_RS19455	COG0697	spore germination
D2M30_RS19460	COG0589	response to stress
D2M30_RS19465	COG2723	6-phospho-beta-galactosidase activity
D2M30_RS19470	COG1263	PTS System
D2M30_RS19470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D2M30_RS19470	COG2190	(PTS) system
D2M30_RS19480	COG0494	nUDIX hydrolase
D2M30_RS19485	COG3507	Belongs to the glycosyl hydrolase 43 family
D2M30_RS19515	COG0010	Belongs to the arginase family
D2M30_RS19520	COG0833	amino acid
D2M30_RS19525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D2M30_RS19530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D2M30_RS19540	COG2390	Transcriptional regulator
D2M30_RS19545	COG0561	phosphatase activity
D2M30_RS19575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D2M30_RS19580	COG5294	Protein conserved in bacteria
D2M30_RS19585	COG0577	efflux transmembrane transporter activity
D2M30_RS19590	COG1136	(ABC) transporter
D2M30_RS19595	COG2205	protein histidine kinase activity
D2M30_RS19600	COG0745	RESPONSE REGULATOR receiver
D2M30_RS19615	COG1082	Xylose isomerase domain protein TIM barrel
D2M30_RS19625	COG2814	Major facilitator Superfamily
D2M30_RS19655	COG1349	DNA-binding transcription factor activity
D2M30_RS19660	COG0667	Aldo Keto reductase
D2M30_RS19665	COG2814	Major facilitator Superfamily
D2M30_RS19675	COG1028	Short-chain dehydrogenase reductase Sdr
D2M30_RS19680	COG2197	response regulator
D2M30_RS19685	COG4585	Histidine kinase
D2M30_RS19690	COG3239	Fatty acid desaturase
D2M30_RS19695	COG1309	transcriptional regulator
D2M30_RS19700	COG1012	belongs to the aldehyde dehydrogenase family
D2M30_RS19705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D2M30_RS19715	COG0640	Transcriptional regulator
D2M30_RS19720	COG2814	Major facilitator Superfamily
D2M30_RS19725	COG1714	RDD family
D2M30_RS19735	COG0450	alkyl hydroperoxide reductase
D2M30_RS19740	COG3634	alkyl hydroperoxide reductase activity
D2M30_RS19750	COG1113	amino acid transport
D2M30_RS19775	COG2080	2 iron, 2 sulfur cluster binding
D2M30_RS19790	COG2068	MobA-Related Protein
D2M30_RS19795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D2M30_RS19845	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D2M30_RS19850	COG0667	Aldo Keto reductase
D2M30_RS19855	COG0456	acetyltransferase
D2M30_RS19860	COG0457	Tetratricopeptide repeat
D2M30_RS19865	COG0010	Belongs to the arginase family
D2M30_RS19870	COG0833	amino acid
D2M30_RS19875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D2M30_RS19880	COG5658	integral membrane protein
D2M30_RS19885	COG0640	Transcriptional regulator
D2M30_RS19890	COG3829	transcription factor binding
D2M30_RS19900	COG0488	(ABC) transporter
D2M30_RS19915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D2M30_RS19920	COG3850	Histidine kinase
D2M30_RS19920	COG5002	protein histidine kinase activity
D2M30_RS19925	COG0745	RESPONSE REGULATOR receiver
D2M30_RS19935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D2M30_RS19940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D2M30_RS19945	COG4853	Protein conserved in bacteria
D2M30_RS19950	COG4863	YycH protein
D2M30_RS19955	COG5002	protein histidine kinase activity
D2M30_RS19960	COG0745	RESPONSE REGULATOR receiver
D2M30_RS19995	COG0346	lactoylglutathione lyase activity
D2M30_RS20000	COG0305	Participates in initiation and elongation during chromosome replication
D2M30_RS20015	COG3093	addiction module antidote protein HigA
D2M30_RS20040	COG0438	transferase activity, transferring glycosyl groups
D2M30_RS20060	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D2M30_RS20065	COG4241	membrane
D2M30_RS20075	COG5577	PFAM Coat F domain
D2M30_RS20080	COG1733	regulation of RNA biosynthetic process
D2M30_RS20090	COG0697	spore germination
D2M30_RS20095	COG1621	beta-fructofuranosidase activity
D2M30_RS20100	COG1621	beta-fructofuranosidase activity
D2M30_RS20105	COG1802	Transcriptional regulator
D2M30_RS20110	COG2318	DinB family
D2M30_RS20115	COG2211	Major facilitator Superfamily
D2M30_RS20130	COG0778	Nitroreductase
D2M30_RS20135	COG1846	Transcriptional regulator
D2M30_RS20140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D2M30_RS20145	COG1846	Transcriptional regulator
D2M30_RS20150	COG2153	protein acetylation
D2M30_RS20155	COG0640	Transcriptional regulator
D2M30_RS20160	COG2267	carboxylic ester hydrolase activity
D2M30_RS20165	COG1331	Highly conserved protein containing a thioredoxin domain
D2M30_RS20170	COG0477	Major facilitator Superfamily
D2M30_RS20185	COG0457	Tetratricopeptide repeat
D2M30_RS20215	COG0791	NLP P60 protein
D2M30_RS20215	COG0741	lytic transglycosylase activity
D2M30_RS20220	COG5644	endopeptidase inhibitor activity
D2M30_RS20230	COG0433	COG0433 Predicted ATPase
D2M30_RS20280	COG2946	Replication initiation factor
D2M30_RS20285	COG1674	ftsk spoiiie
D2M30_RS20310	COG1396	sequence-specific DNA binding
D2M30_RS20315	COG2856	Zn peptidase
D2M30_RS20330	COG1331	Highly conserved protein containing a thioredoxin domain
D2M30_RS20335	COG1331	Highly conserved protein containing a thioredoxin domain
D2M30_RS20340	COG1266	CAAX protease self-immunity
D2M30_RS20345	COG2814	Major facilitator Superfamily
D2M30_RS20345	COG0477	Major facilitator Superfamily
D2M30_RS20350	COG0346	lactoylglutathione lyase activity
D2M30_RS20355	COG1609	Transcriptional regulator
D2M30_RS20360	COG0708	Exodeoxyribonuclease III
D2M30_RS20365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D2M30_RS20370	COG2169	Transcriptional regulator
D2M30_RS20380	COG0629	single-stranded DNA binding
D2M30_RS20390	COG0012	GTP binding
D2M30_RS20395	COG0243	molybdopterin cofactor binding
D2M30_RS20400	COG4481	Protein conserved in bacteria
D2M30_RS20405	COG3949	Membrane
D2M30_RS20420	COG1475	DNA binding
D2M30_RS20425	COG1192	Involved in chromosome partitioning
D2M30_RS20450	COG1847	R3H domain protein
D2M30_RS20455	COG0706	membrane insertase activity