locus-tag	class	description
KD35_RS00020	COG1271	oxidase subunit
KD35_RS00025	COG1294	oxidase, subunit
KD35_RS00030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_RS00040	COG1620	l-lactate permease
KD35_RS00050	COG2389	metal-binding protein
KD35_RS00060	COG1368	sulfuric ester hydrolase activity
KD35_RS00075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS00085	COG1215	transferase activity, transferring glycosyl groups
KD35_RS00095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_RS00100	COG1388	LysM domain
KD35_RS00100	COG3584	3D domain protein
KD35_RS00125	COG4715	Zinc finger, swim domain protein
KD35_RS00130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_RS00170	COG0577	efflux transmembrane transporter activity
KD35_RS00175	COG1136	(ABC) transporter
KD35_RS00210	COG5002	protein histidine kinase activity
KD35_RS00215	COG0745	RESPONSE REGULATOR receiver
KD35_RS00220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KD35_RS00235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KD35_RS00240	COG1134	teichoic acid transport
KD35_RS00245	COG1682	transport, permease protein
KD35_RS00250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KD35_RS00295	COG1609	Transcriptional regulator
KD35_RS00310	COG0739	heme binding
KD35_RS00325	COG3279	Response regulator of the LytR AlgR family
KD35_RS00330	COG4555	ABC transporter
KD35_RS00335	COG2385	sporulation resulting in formation of a cellular spore
KD35_RS00350	COG4836	Membrane
KD35_RS00355	COG1007	ATP synthesis coupled electron transport
KD35_RS00360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KD35_RS00365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KD35_RS00375	COG0839	Belongs to the complex I subunit 6 family
KD35_RS00390	COG0649	NAD binding
KD35_RS00395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KD35_RS00410	COG3300	MHYT domain
KD35_RS00410	COG5001	Diguanylate cyclase
KD35_RS00460	COG0356	it plays a direct role in the translocation of protons across the membrane
KD35_RS00495	COG0698	ribose 5-phosphate isomerase
KD35_RS00505	COG2190	(PTS) system
KD35_RS00510	COG2259	Doxx family
KD35_RS00515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KD35_RS00530	COG0009	L-threonylcarbamoyladenylate synthase
KD35_RS00545	COG2890	protein-(glutamine-N5) methyltransferase activity
KD35_RS00565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KD35_RS00570	COG1494	fructose-1,6-bisphosphatase
KD35_RS00590	COG4821	SIS domain
KD35_RS00600	COG3343	RNA polymerase activity
KD35_RS00610	COG1960	acyl-CoA dehydrogenase activity
KD35_RS00615	COG1960	acyl-CoA dehydrogenase activity
KD35_RS00620	COG1250	3-hydroxyacyl-CoA dehydrogenase
KD35_RS00625	COG0183	Belongs to the thiolase family
KD35_RS00630	COG2181	nitrate reductase activity
KD35_RS00630	COG0247	lactate metabolic process
KD35_RS00635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_RS00645	COG5001	Diguanylate cyclase
KD35_RS00645	COG3300	MHYT domain
KD35_RS00660	COG2197	response regulator
KD35_RS00665	COG4585	Histidine kinase
KD35_RS00670	COG0842	Transport permease protein
KD35_RS00675	COG1131	(ABC) transporter
KD35_RS00680	COG0024	Methionine aminopeptidase
KD35_RS00700	COG2234	aminopeptidase activity
KD35_RS00720	COG1595	DNA-templated transcription, initiation
KD35_RS00725	COG0018	arginyl-trna synthetase
KD35_RS00730	COG4506	Protein conserved in bacteria
KD35_RS00735	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_RS00755	COG0010	Belongs to the arginase family
KD35_RS00765	COG2814	Major facilitator Superfamily
KD35_RS00770	COG0789	Transcriptional regulator
KD35_RS00775	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_RS00780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_RS00790	COG1994	Peptidase M50
KD35_RS00800	COG1078	dGTPase activity
KD35_RS00805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS00810	COG1120	ATPase activity
KD35_RS00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS00820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS00825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS00845	COG0095	Lipoate-protein ligase
KD35_RS00850	COG0280	phosphate acetyltransferase
KD35_RS00865	COG3773	Cell wall hydrolase
KD35_RS00875	COG2363	Small membrane protein
KD35_RS00885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KD35_RS00890	COG2233	PERMEase
KD35_RS00895	COG0561	phosphatase activity
KD35_RS00900	COG2814	Major facilitator Superfamily
KD35_RS00910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_RS00915	COG1131	(ABC) transporter
KD35_RS00920	COG2755	lipolytic protein G-D-S-L family
KD35_RS00925	COG1609	Transcriptional regulator
KD35_RS00935	COG0460	homoserine dehydrogenase
KD35_RS00945	COG2873	o-acetylhomoserine
KD35_RS00955	COG1011	Hydrolase
KD35_RS00960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KD35_RS00970	COG2197	response regulator
KD35_RS00980	COG0351	phosphomethylpyrimidine kinase
KD35_RS00985	COG3706	GGDEF domain
KD35_RS00990	COG2879	small protein
KD35_RS00995	COG1966	Carbon starvation protein
KD35_RS01000	COG3279	Response regulator of the LytR AlgR family
KD35_RS01005	COG0477	Major facilitator Superfamily
KD35_RS01030	COG0840	transmembrane signaling receptor activity
KD35_RS01040	COG1607	acyl-coa hydrolase
KD35_RS01055	COG0488	(ABC) transporter
KD35_RS01080	COG0463	Glycosyl transferase, family 2
KD35_RS01085	COG1309	transcriptional regulator
KD35_RS01090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KD35_RS01095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_RS01095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_RS01100	COG0628	permease
KD35_RS01115	COG3279	Response regulator of the LytR AlgR family
KD35_RS01120	COG3275	phosphorelay sensor kinase activity
KD35_RS01125	COG2814	Major facilitator Superfamily
KD35_RS01130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_RS01135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KD35_RS01140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_RS01160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KD35_RS01165	COG1272	protein, Hemolysin III
KD35_RS01185	COG0516	GMP reductase activity
KD35_RS01190	COG1164	Oligoendopeptidase f
KD35_RS01210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_RS01215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KD35_RS01220	COG4853	Protein conserved in bacteria
KD35_RS01225	COG4863	YycH protein
KD35_RS01230	COG5002	protein histidine kinase activity
KD35_RS01235	COG0745	RESPONSE REGULATOR receiver
KD35_RS01265	COG0305	Participates in initiation and elongation during chromosome replication
KD35_RS01275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KD35_RS01280	COG4241	membrane
KD35_RS01290	COG0629	single-stranded DNA binding
KD35_RS01300	COG0012	GTP binding
KD35_RS01305	COG4481	Protein conserved in bacteria
KD35_RS01310	COG0668	transmembrane transport
KD35_RS01320	COG1475	DNA binding
KD35_RS01325	COG1192	Involved in chromosome partitioning
KD35_RS01350	COG1847	R3H domain protein
KD35_RS01355	COG0706	membrane insertase activity
KD35_RS01365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KD35_RS01375	COG0592	DNA-directed DNA polymerase activity
KD35_RS01380	COG2501	S4 domain
KD35_RS01390	COG0187	DNA topoisomerase II activity
KD35_RS01395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KD35_RS01430	COG0517	IMP dehydrogenase activity
KD35_RS01430	COG0516	GMP reductase activity
KD35_RS01435	COG1686	Belongs to the peptidase S11 family
KD35_RS01465	COG1428	Deoxynucleoside kinase
KD35_RS01470	COG1428	Deoxynucleoside kinase
KD35_RS01475	COG1335	isochorismatase
KD35_RS01485	COG0590	tRNA wobble adenosine to inosine editing
KD35_RS01490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KD35_RS01545	COG1982	Orn Lys Arg decarboxylase major
KD35_RS01555	COG0470	DNA polymerase III
KD35_RS01560	COG1774	PSP1 C-terminal conserved region
KD35_RS01570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KD35_RS01580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KD35_RS01585	COG2002	toxin-antitoxin pair type II binding
KD35_RS01590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_RS01590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_RS01595	COG0084	hydrolase, TatD family'
KD35_RS01600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KD35_RS01615	COG4466	Protein conserved in bacteria
KD35_RS01630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KD35_RS01635	COG0251	oxidation-reduction process
KD35_RS01665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KD35_RS01670	COG2002	toxin-antitoxin pair type II binding
KD35_RS01675	COG2244	polysaccharide biosynthetic process
KD35_RS01680	COG3956	TIGRFAM MazG family protein
KD35_RS01685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KD35_RS01705	COG1098	S1 RNA binding domain
KD35_RS01720	COG2208	phosphoserine phosphatase activity
KD35_RS01725	COG0037	tRNA processing
KD35_RS01730	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KD35_RS01735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KD35_RS01750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_RS01755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KD35_RS01760	COG0512	Glutamine amidotransferase of anthranilate synthase
KD35_RS01765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_RS01770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KD35_RS01775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KD35_RS01780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KD35_RS01785	COG1396	sequence-specific DNA binding
KD35_RS01790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KD35_RS01820	COG3880	PFAM UvrB UvrC protein
KD35_RS01830	COG0542	response to heat
KD35_RS01835	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KD35_RS01845	COG4956	integral membrane protein (PIN domain superfamily)
KD35_RS01865	COG1045	serine acetyltransferase
KD35_RS01880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KD35_RS01885	COG3688	RNA-binding protein containing a PIN domain
KD35_RS01900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KD35_RS01905	COG0250	Participates in transcription elongation, termination and antitermination
KD35_RS01910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KD35_RS01930	COG2813	Specifically methylates the guanine in position
KD35_RS01940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KD35_RS01945	COG1358	cellular component organization or biogenesis
KD35_RS02015	COG0255	Belongs to the universal ribosomal protein uL29 family
KD35_RS02075	COG0201	protein transport
KD35_RS02085	COG0024	Methionine aminopeptidase
KD35_RS02095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KD35_RS02130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KD35_RS02155	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_RS02160	COG0489	protein tyrosine kinase activity
KD35_RS02170	COG2194	sulfuric ester hydrolase activity
KD35_RS02175	COG0726	polysaccharide deacetylase
KD35_RS02260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KD35_RS02265	COG4856	YbbR-like protein
KD35_RS02280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KD35_RS02285	COG0596	Alpha beta hydrolase
KD35_RS02305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KD35_RS02310	COG4946	Tricorn protease homolog
KD35_RS02310	COG1506	peptidase
KD35_RS02310	COG0823	Involved in the tonB-independent uptake of proteins
KD35_RS02345	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS02350	COG2011	ABC-type metal ion transport system permease component
KD35_RS02355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_RS02360	COG1464	Belongs to the NlpA lipoprotein family
KD35_RS02365	COG0604	alcohol dehydrogenase
KD35_RS02375	COG0277	FAD linked oxidase domain protein
KD35_RS02380	COG2271	Major facilitator Superfamily
KD35_RS02390	COG2814	Major facilitator Superfamily
KD35_RS02405	COG0601	transmembrane transport
KD35_RS02410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_RS02415	COG0444	Belongs to the ABC transporter superfamily
KD35_RS02420	COG4608	Belongs to the ABC transporter superfamily
KD35_RS02425	COG4166	transmembrane transport
KD35_RS02435	COG2207	Transcriptional regulator
KD35_RS02450	COG4166	transmembrane transport
KD35_RS02455	COG4166	transmembrane transport
KD35_RS02460	COG0656	L-ascorbic acid biosynthetic process
KD35_RS02465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_RS02485	COG4149	molybdate abc transporter
KD35_RS02490	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_RS02495	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_RS02500	COG1910	domain protein
KD35_RS02515	COG0583	DNA-binding transcription factor activity
KD35_RS02520	COG0697	spore germination
KD35_RS02530	COG0204	Acyl-transferase
KD35_RS02540	COG1609	Transcriptional regulator
KD35_RS02550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS02565	COG0084	hydrolase, TatD family'
KD35_RS02570	COG5298	Protein conserved in bacteria
KD35_RS02595	COG0488	(ABC) transporter
KD35_RS02610	COG0747	negative chemotaxis
KD35_RS02615	COG0601	transmembrane transport
KD35_RS02620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_RS02625	COG0444	Belongs to the ABC transporter superfamily
KD35_RS02630	COG4608	Belongs to the ABC transporter superfamily
KD35_RS02670	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KD35_RS02675	COG0179	Fumarylacetoacetate (FAA) hydrolase
KD35_RS02685	COG2814	Major facilitator Superfamily
KD35_RS02700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KD35_RS02710	COG4294	response to UV
KD35_RS02715	COG0705	Rhomboid family
KD35_RS02715	COG0457	Tetratricopeptide repeat
KD35_RS02725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KD35_RS02730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KD35_RS02735	COG0864	Transcriptional regulator
KD35_RS02740	COG2337	Toxic component of a toxin-antitoxin (TA) module
KD35_RS02745	COG2183	response to ionizing radiation
KD35_RS02840	COG0802	atpase or kinase
KD35_RS02845	COG1214	PFAM Peptidase M22, glycoprotease
KD35_RS02850	COG0456	acetyltransferase
KD35_RS02860	COG0488	(ABC) transporter
KD35_RS02875	COG1266	CAAX protease self-immunity
KD35_RS02895	COG2252	PERMEase
KD35_RS02905	COG5002	protein histidine kinase activity
KD35_RS02935	COG2226	methyltransferase
KD35_RS02975	COG1968	undecaprenyl-diphosphatase activity
KD35_RS02990	COG2205	protein histidine kinase activity
KD35_RS02995	COG0745	RESPONSE REGULATOR receiver
KD35_RS03015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KD35_RS03020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KD35_RS03025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KD35_RS03035	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KD35_RS03050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KD35_RS03060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KD35_RS03070	COG0151	Belongs to the GarS family
KD35_RS03095	COG0210	DNA helicase
KD35_RS03105	COG4851	CamS sex pheromone cAM373 precursor
KD35_RS03125	COG1335	isochorismatase
KD35_RS03130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_RS03135	COG2011	ABC-type metal ion transport system permease component
KD35_RS03140	COG1464	Belongs to the NlpA lipoprotein family
KD35_RS03160	COG1846	Transcriptional regulator
KD35_RS03185	COG1597	lipid kinase activity
KD35_RS03190	COG0546	phosphoglycolate phosphatase activity
KD35_RS03195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KD35_RS03205	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS03210	COG2076	Multidrug Resistance protein
KD35_RS03215	COG2309	aminopeptidase activity
KD35_RS03230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS03235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KD35_RS03240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KD35_RS03250	COG4807	Protein conserved in bacteria
KD35_RS03275	COG1757	Na H antiporter
KD35_RS03280	COG1473	amidohydrolase
KD35_RS03295	COG0450	alkyl hydroperoxide reductase
KD35_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS03345	COG0166	Belongs to the GPI family
KD35_RS03380	COG5002	protein histidine kinase activity
KD35_RS03400	COG3541	Predicted nucleotidyltransferase
KD35_RS03405	COG2814	Major facilitator Superfamily
KD35_RS03410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_RS03410	COG0723	plastoquinol--plastocyanin reductase activity
KD35_RS03420	COG0765	amino acid transport
KD35_RS03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_RS03440	COG0840	transmembrane signaling receptor activity
KD35_RS03445	COG0840	transmembrane signaling receptor activity
KD35_RS03450	COG0366	Alpha amylase catalytic
KD35_RS03455	COG2190	(PTS) system
KD35_RS03455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS03455	COG1263	PTS System
KD35_RS03485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KD35_RS03500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_RS03510	COG1116	anion transmembrane transporter activity
KD35_RS03515	COG0488	(ABC) transporter
KD35_RS03560	COG2270	Major facilitator Superfamily
KD35_RS03575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_RS03590	COG2310	stress, protein
KD35_RS03595	COG2310	stress, protein
KD35_RS03600	COG2310	stress, protein
KD35_RS03605	COG0861	Integral membrane protein TerC family
KD35_RS03615	COG3853	Toxic anion resistance protein (TelA)
KD35_RS03630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KD35_RS03640	COG1295	ribonuclease BN
KD35_RS03645	COG2217	Heavy metal translocating P-type atpase
KD35_RS03650	COG0697	spore germination
KD35_RS03670	COG0586	Pfam SNARE associated Golgi protein
KD35_RS03685	COG3871	stress protein (general stress protein 26)
KD35_RS03690	COG0387	Pfam Sodium calcium exchanger
KD35_RS03700	COG0535	radical SAM domain protein
KD35_RS03725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KD35_RS03730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KD35_RS03735	COG0582	viral genome integration into host DNA
KD35_RS03740	COG1396	sequence-specific DNA binding
KD35_RS03755	COG1396	sequence-specific DNA binding
KD35_RS03790	COG1484	DNA-dependent DNA replication
KD35_RS03885	COG0582	viral genome integration into host DNA
KD35_RS03890	COG0582	viral genome integration into host DNA
KD35_RS04015	COG0101	tRNA pseudouridine synthase activity
KD35_RS04025	COG3829	transcription factor binding
KD35_RS04035	COG0833	amino acid
KD35_RS04040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_RS04075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS04075	COG1263	PTS System
KD35_RS04080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_RS04095	COG0463	Glycosyl transferase, family 2
KD35_RS04110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_RS04110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KD35_RS04130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KD35_RS04150	COG1228	amidohydrolase
KD35_RS04155	COG1090	epimerase
KD35_RS04185	COG1988	membrane-bound metal-dependent
KD35_RS04190	COG1194	a g-specific adenine glycosylase
KD35_RS04215	COG1132	(ABC) transporter
KD35_RS04220	COG4129	membrane
KD35_RS04225	COG0070	glutamate synthase
KD35_RS04225	COG0069	glutamate synthase activity
KD35_RS04225	COG0067	glutamate synthase
KD35_RS04235	COG4555	ABC transporter
KD35_RS04255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KD35_RS04260	COG0735	belongs to the Fur family
KD35_RS04375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KD35_RS04380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KD35_RS04390	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KD35_RS04400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KD35_RS04415	COG2766	serine protein kinase
KD35_RS04440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_RS04450	COG1585	Membrane protein implicated in regulation of membrane protease activity
KD35_RS04455	COG2268	Band 7 protein
KD35_RS04465	COG3290	protein histidine kinase activity
KD35_RS04470	COG4565	transcriptional regulatory protein
KD35_RS04475	COG2851	Citrate transporter
KD35_RS04495	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KD35_RS04500	COG3842	ATPase activity
KD35_RS04505	COG1175	transmembrane transport
KD35_RS04510	COG0395	ABC-type sugar transport system, permease component
KD35_RS04520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KD35_RS04525	COG0745	RESPONSE REGULATOR receiver
KD35_RS04530	COG5002	protein histidine kinase activity
KD35_RS04540	COG4990	cell redox homeostasis
KD35_RS04550	COG3290	protein histidine kinase activity
KD35_RS04555	COG4565	transcriptional regulatory protein
KD35_RS04560	COG3493	citrate carrier protein
KD35_RS04565	COG0281	malic enzyme
KD35_RS04580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS04590	COG5002	protein histidine kinase activity
KD35_RS04595	COG0745	RESPONSE REGULATOR receiver
KD35_RS04605	COG0456	acetyltransferase
KD35_RS04605	COG0454	-acetyltransferase
KD35_RS04610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KD35_RS04615	COG3383	formate dehydrogenase (NAD+) activity
KD35_RS04620	COG2427	Protein of unknown function (DUF1641)
KD35_RS04635	COG0531	amino acid
KD35_RS04640	COG0640	Transcriptional regulator
KD35_RS04645	COG2217	Heavy metal translocating P-type atpase
KD35_RS04650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KD35_RS04660	COG3227	Zinc metalloprotease (Elastase)
KD35_RS04680	COG2720	vancomycin resistance protein
KD35_RS04685	COG1316	TRANSCRIPTIONal
KD35_RS04690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS04695	COG0346	lactoylglutathione lyase activity
KD35_RS04700	COG1253	flavin adenine dinucleotide binding
KD35_RS04705	COG1027	Aspartate ammonia-lyase
KD35_RS04710	COG1620	l-lactate permease
KD35_RS04725	COG3104	oligopeptide transport
KD35_RS04730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS04735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS04750	COG2226	methyltransferase
KD35_RS04755	COG0156	8-amino-7-oxononanoate synthase activity
KD35_RS04760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_RS04770	COG4548	von Willebrand factor, type A
KD35_RS04775	COG0714	Associated with various cellular activities
KD35_RS04780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_RS04800	COG0531	amino acid
KD35_RS04805	COG2188	Transcriptional regulator
KD35_RS04810	COG1263	PTS System
KD35_RS04810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS04815	COG0366	Alpha amylase catalytic
KD35_RS04830	COG0697	spore germination
KD35_RS04840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_RS04845	COG1115	amino acid carrier protein
KD35_RS04850	COG1126	abc transporter atp-binding protein
KD35_RS04855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_RS04860	COG0765	amino acid transport
KD35_RS04865	COG0765	amino acid transport
KD35_RS04870	COG0833	amino acid
KD35_RS04895	COG2378	regulation of single-species biofilm formation
KD35_RS04900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KD35_RS04905	COG5002	protein histidine kinase activity
KD35_RS04920	COG0659	secondary active sulfate transmembrane transporter activity
KD35_RS04935	COG0747	negative chemotaxis
KD35_RS04945	COG0601	transmembrane transport
KD35_RS04950	COG4608	Belongs to the ABC transporter superfamily
KD35_RS04960	COG2271	Major facilitator Superfamily
KD35_RS04965	COG1846	Transcriptional regulator
KD35_RS04970	COG0477	Major facilitator Superfamily
KD35_RS04975	COG0477	Major facilitator Superfamily
KD35_RS04980	COG1609	Transcriptional regulator
KD35_RS04985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KD35_RS05000	COG1172	Belongs to the binding-protein-dependent transport system permease family
KD35_RS05005	COG1879	ABC-type sugar transport system periplasmic component
KD35_RS05030	COG1063	alcohol dehydrogenase
KD35_RS05045	COG3568	Endonuclease Exonuclease Phosphatase
KD35_RS05070	COG1968	undecaprenyl-diphosphatase activity
KD35_RS05075	COG0840	transmembrane signaling receptor activity
KD35_RS05080	COG3584	3D domain protein
KD35_RS05080	COG1388	LysM domain
KD35_RS05085	COG1476	TRANSCRIPTIONal
KD35_RS05100	COG3104	oligopeptide transport
KD35_RS05105	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS05120	COG1113	amino acid transport
KD35_RS05125	COG2252	PERMEase
KD35_RS05150	COG0569	domain protein
KD35_RS05150	COG0475	glutathione-regulated potassium exporter activity
KD35_RS05165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KD35_RS05170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KD35_RS05175	COG0833	amino acid
KD35_RS05180	COG4990	cell redox homeostasis
KD35_RS05195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_RS05200	COG0697	spore germination
KD35_RS05205	COG0531	amino acid
KD35_RS05220	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_RS05225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_RS05230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_RS05230	COG1918	ferrous iron import across plasma membrane
KD35_RS05235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KD35_RS05240	COG0573	inorganic phosphate transmembrane transporter activity
KD35_RS05245	COG0581	inorganic phosphate transmembrane transporter activity
KD35_RS05255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KD35_RS05375	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KD35_RS05400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KD35_RS05405	COG1116	anion transmembrane transporter activity
KD35_RS05410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_RS05415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_RS05420	COG0352	thiamine-phosphate diphosphorylase activity
KD35_RS05425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_RS05430	COG2104	thiamine diphosphate biosynthetic process
KD35_RS05440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_RS05445	COG0351	phosphomethylpyrimidine kinase
KD35_RS05490	COG2205	protein histidine kinase activity
KD35_RS05495	COG2814	Major facilitator Superfamily
KD35_RS05500	COG1846	Transcriptional regulator
KD35_RS05515	COG2252	PERMEase
KD35_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS05535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KD35_RS05545	COG1263	PTS System
KD35_RS05545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS05550	COG1609	Transcriptional regulator
KD35_RS05560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_RS05565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KD35_RS05605	COG0778	Nitroreductase
KD35_RS05610	COG2719	SpoVR family
KD35_RS05635	COG0446	pyridine nucleotide-disulphide oxidoreductase
KD35_RS05640	COG1937	Protein conserved in bacteria
KD35_RS05645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS05645	COG0425	Belongs to the sulfur carrier protein TusA family
KD35_RS05650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS05650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS05655	COG0425	Belongs to the sulfur carrier protein TusA family
KD35_RS05660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS05670	COG2210	Belongs to the sulfur carrier protein TusA family
KD35_RS05675	COG0730	response to heat
KD35_RS05685	COG1316	TRANSCRIPTIONal
KD35_RS05690	COG0604	alcohol dehydrogenase
KD35_RS05695	COG1283	sodium-dependent phosphate transmembrane transporter activity
KD35_RS05710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_RS05710	COG3711	transcriptional antiterminator
KD35_RS05715	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_RS05720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_RS05740	COG3584	3D domain protein
KD35_RS05740	COG1388	LysM domain
KD35_RS05745	COG0577	efflux transmembrane transporter activity
KD35_RS05750	COG1136	(ABC) transporter
KD35_RS05760	COG5522	Integral membrane protein (intg_mem_TP0381)
KD35_RS05775	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS05780	COG3546	catalase activity
KD35_RS05815	COG0586	Pfam SNARE associated Golgi protein
KD35_RS05850	COG0531	amino acid
KD35_RS05855	COG0475	glutathione-regulated potassium exporter activity
KD35_RS05865	COG1737	Transcriptional regulator
KD35_RS05875	COG1263	PTS System
KD35_RS05875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS05885	COG2259	Doxx family
KD35_RS05900	COG0697	spore germination
KD35_RS05905	COG1522	sequence-specific DNA binding
KD35_RS05920	COG2076	Multidrug Resistance protein
KD35_RS05925	COG1309	transcriptional regulator
KD35_RS05930	COG2814	Major facilitator Superfamily
KD35_RS05935	COG1733	regulation of RNA biosynthetic process
KD35_RS05945	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_RS05950	COG4533	DNA binding
KD35_RS05955	COG2211	Major facilitator Superfamily
KD35_RS05965	COG0693	protein deglycase activity
KD35_RS05970	COG0693	protein deglycase activity
KD35_RS05970	COG0753	catalase activity
KD35_RS05980	COG0531	amino acid
KD35_RS05985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KD35_RS05995	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS06005	COG1132	(ABC) transporter
KD35_RS06015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_RS06020	COG0765	amino acid transport
KD35_RS06025	COG1126	abc transporter atp-binding protein
KD35_RS06040	COG0189	ligase activity
KD35_RS06070	COG0028	Belongs to the TPP enzyme family
KD35_RS06075	COG3527	Alpha-acetolactate decarboxylase
KD35_RS06090	COG0561	phosphatase activity
KD35_RS06105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KD35_RS06120	COG0659	secondary active sulfate transmembrane transporter activity
KD35_RS06140	COG0653	protein targeting
KD35_RS06145	COG2244	polysaccharide biosynthetic process
KD35_RS06155	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_RS06160	COG4196	transglutaminase domain protein
KD35_RS06175	COG1696	Membrane protein involved in D-alanine export
KD35_RS06190	COG1024	Enoyl-CoA hydratase
KD35_RS06210	COG1363	Peptidase, m42
KD35_RS06230	COG3938	Belongs to the proline racemase family
KD35_RS06270	COG0601	transmembrane transport
KD35_RS06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_RS06285	COG4608	Belongs to the ABC transporter superfamily
KD35_RS06315	COG0477	Major facilitator Superfamily
KD35_RS06320	COG3290	protein histidine kinase activity
KD35_RS06325	COG4565	transcriptional regulatory protein
KD35_RS06330	COG3181	Tripartite tricarboxylate transporter family receptor
KD35_RS06360	COG4978	Transcriptional regulator
KD35_RS06360	COG0789	Transcriptional regulator
KD35_RS06375	COG0305	Participates in initiation and elongation during chromosome replication
KD35_RS06415	COG0477	Major facilitator Superfamily
KD35_RS06465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KD35_RS06465	COG3320	Male sterility
KD35_RS06470	COG1309	transcriptional regulator
KD35_RS06490	COG1183	phosphatidylcholine synthase activity
KD35_RS06510	COG2376	Dihydroxyacetone kinase
KD35_RS06525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_RS06530	COG1959	2 iron, 2 sulfur cluster binding
KD35_RS06555	COG3437	response regulator, receiver
KD35_RS06555	COG2770	Histidine kinase
KD35_RS06605	COG3237	CsbD-like
KD35_RS06630	COG1191	sigma factor activity
KD35_RS06640	COG2208	phosphoserine phosphatase activity
KD35_RS06645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KD35_RS06650	COG2198	Histidine kinase
KD35_RS06650	COG2205	protein histidine kinase activity
KD35_RS06650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_RS06650	COG0784	Response regulator, receiver
KD35_RS06710	COG0420	3'-5' exonuclease activity
KD35_RS06715	COG4717	serine-type aminopeptidase activity
KD35_RS06735	COG1309	transcriptional regulator
KD35_RS06740	COG2814	Major facilitator Superfamily
KD35_RS06745	COG0346	lactoylglutathione lyase activity
KD35_RS06750	COG0346	lactoylglutathione lyase activity
KD35_RS06755	COG0457	Tetratricopeptide repeat
KD35_RS06760	COG2267	carboxylic ester hydrolase activity
KD35_RS06780	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KD35_RS06785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KD35_RS06795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KD35_RS06835	COG0477	Major facilitator Superfamily
KD35_RS06840	COG0477	Major facilitator Superfamily
KD35_RS06850	COG3973	AAA domain
KD35_RS06855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_RS06880	COG4980	gas vesicle protein
KD35_RS06885	COG0537	adenosine 5'-monophosphoramidase activity
KD35_RS06890	COG1131	(ABC) transporter
KD35_RS06895	COG4473	ABC transporter
KD35_RS06905	COG1309	transcriptional regulator
KD35_RS06915	COG3402	PFAM membrane-flanked domain
KD35_RS06925	COG3428	Bacterial PH domain
KD35_RS06965	COG3402	PFAM membrane-flanked domain
KD35_RS06970	COG3428	Bacterial PH domain
KD35_RS06975	COG2329	Antibiotic biosynthesis monooxygenase
KD35_RS06980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_RS06985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KD35_RS06990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KD35_RS06995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KD35_RS07030	COG1309	transcriptional regulator
KD35_RS07035	COG1511	domain protein
KD35_RS07060	COG1609	Transcriptional regulator
KD35_RS07070	COG1234	tRNA 3'-trailer cleavage
KD35_RS07075	COG0095	Lipoate-protein ligase
KD35_RS07085	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS07115	COG3209	COG3209 Rhs family protein
KD35_RS07160	COG1408	metallophosphoesterase
KD35_RS07165	COG1078	dGTPase activity
KD35_RS07175	COG1595	DNA-templated transcription, initiation
KD35_RS07180	COG2207	Transcriptional regulator
KD35_RS07180	COG3708	Transcriptional regulator
KD35_RS07195	COG2205	protein histidine kinase activity
KD35_RS07200	COG0745	RESPONSE REGULATOR receiver
KD35_RS07225	COG0501	Belongs to the peptidase M48B family
KD35_RS07230	COG0840	transmembrane signaling receptor activity
KD35_RS07235	COG0697	spore germination
KD35_RS07255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KD35_RS07260	COG2224	Isocitrate lyase
KD35_RS07285	COG4903	ComK protein
KD35_RS07290	COG0398	Pfam SNARE associated Golgi protein
KD35_RS07300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KD35_RS07305	COG1074	ATP-dependent DNA helicase activity
KD35_RS07350	COG0179	Fumarylacetoacetate (FAA) hydrolase
KD35_RS07375	COG0367	asparagine synthase
KD35_RS07380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KD35_RS07385	COG0753	catalase activity
KD35_RS07390	COG0004	ammonium transporteR
KD35_RS07415	COG2996	Protein conserved in bacteria
KD35_RS07425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_RS07435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS07450	COG0561	phosphatase activity
KD35_RS07465	COG0542	response to heat
KD35_RS07475	COG2267	carboxylic ester hydrolase activity
KD35_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS07495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KD35_RS07500	COG5504	Zn-dependent protease
KD35_RS07510	COG0180	Tryptophanyl-tRNA synthetase
KD35_RS07520	COG4166	transmembrane transport
KD35_RS07525	COG0601	transmembrane transport
KD35_RS07530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_RS07535	COG0444	Belongs to the ABC transporter superfamily
KD35_RS07540	COG4608	Belongs to the ABC transporter superfamily
KD35_RS07545	COG0534	Mate efflux family protein
KD35_RS07550	COG4166	transmembrane transport
KD35_RS07570	COG0861	Integral membrane protein TerC family
KD35_RS07575	COG4862	establishment of competence for transformation
KD35_RS07580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_RS07590	COG1164	Oligoendopeptidase f
KD35_RS07600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KD35_RS07605	COG2346	COG2346, Truncated hemoglobins
KD35_RS07610	COG4116	CYTH
KD35_RS07620	COG2357	RelA SpoT domain protein
KD35_RS07630	COG0564	pseudouridine synthase activity
KD35_RS07645	COG0772	Belongs to the SEDS family
KD35_RS07650	COG1216	Glycosyl transferase, family 2
KD35_RS07650	COG0463	Glycosyl transferase, family 2
KD35_RS07670	COG0463	Glycosyl transferase, family 2
KD35_RS07670	COG0457	Tetratricopeptide repeat
KD35_RS07690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KD35_RS07705	COG1091	dTDP-4-dehydrorhamnose reductase activity
KD35_RS07750	COG2153	protein acetylation
KD35_RS07760	COG2382	esterase
KD35_RS07775	COG5492	domain, Protein
KD35_RS07780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_RS07795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KD35_RS07795	COG0512	Glutamine amidotransferase of anthranilate synthase
KD35_RS07830	COG1620	l-lactate permease
KD35_RS07835	COG5634	Uncharacterized conserved protein (DUF2278)
KD35_RS07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_RS07895	COG1476	TRANSCRIPTIONal
KD35_RS07955	COG2226	methyltransferase
KD35_RS07965	COG1686	Belongs to the peptidase S11 family
KD35_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS07995	COG3842	ATPase activity
KD35_RS08000	COG1176	ABC-type spermidine putrescine transport system, permease component I
KD35_RS08005	COG1177	transmembrane transport
KD35_RS08010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KD35_RS08020	COG2409	Drug exporters of the RND superfamily
KD35_RS08030	COG0564	pseudouridine synthase activity
KD35_RS08040	COG2340	Cysteine-rich secretory protein family
KD35_RS08045	COG0247	lactate metabolic process
KD35_RS08050	COG0277	FAD linked oxidase domain protein
KD35_RS08055	COG3835	regulator
KD35_RS08065	COG0745	RESPONSE REGULATOR receiver
KD35_RS08070	COG5002	protein histidine kinase activity
KD35_RS08075	COG2186	Transcriptional regulator
KD35_RS08095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KD35_RS08105	COG2116	formate transmembrane transporter activity
KD35_RS08110	COG0861	Integral membrane protein TerC family
KD35_RS08115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_RS08125	COG2030	dehydratase
KD35_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS08150	COG3243	poly(R)-hydroxyalkanoic acid synthase
KD35_RS08155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_RS08160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_RS08175	COG1840	ABC-type Fe3 transport system, periplasmic component
KD35_RS08205	COG1349	DNA-binding transcription factor activity
KD35_RS08230	COG2861	carbohydrate metabolic process
KD35_RS08240	COG3852	Histidine kinase
KD35_RS08245	COG1846	Transcriptional regulator
KD35_RS08255	COG2318	DinB family
KD35_RS08265	COG5002	protein histidine kinase activity
KD35_RS08275	COG0720	synthase
KD35_RS08290	COG4873	Protein conserved in bacteria
KD35_RS08325	COG1780	Probably involved in ribonucleotide reductase function
KD35_RS08340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KD35_RS08345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KD35_RS08350	COG1725	Transcriptional regulator
KD35_RS08355	COG1131	(ABC) transporter
KD35_RS08365	COG1131	(ABC) transporter
KD35_RS08370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_RS08385	COG1522	sequence-specific DNA binding
KD35_RS08395	COG1335	isochorismatase
KD35_RS08405	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_RS08410	COG2070	2-Nitropropane dioxygenase
KD35_RS08415	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KD35_RS08425	COG1696	Membrane protein involved in D-alanine export
KD35_RS08450	COG0716	FMN binding
KD35_RS08465	COG3173	Aminoglycoside phosphotransferase
KD35_RS08485	COG0534	Mate efflux family protein
KD35_RS08490	COG1968	undecaprenyl-diphosphatase activity
KD35_RS08505	COG1846	Transcriptional regulator
KD35_RS08515	COG1301	dicarboxylic acid transport
KD35_RS08520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_RS08525	COG4709	membrane
KD35_RS08530	COG3874	Sporulation protein YtfJ
KD35_RS08560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_RS08565	COG0028	Belongs to the TPP enzyme family
KD35_RS08570	COG0440	acetolactate synthase activity
KD35_RS08575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KD35_RS08585	COG0473	3-isopropylmalate dehydrogenase activity
KD35_RS08610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KD35_RS08645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KD35_RS08660	COG1183	phosphatidylcholine synthase activity
KD35_RS08665	COG1368	sulfuric ester hydrolase activity
KD35_RS08675	COG0019	diaminopimelate decarboxylase activity
KD35_RS08695	COG0529	Catalyzes the synthesis of activated sulfate
KD35_RS08700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KD35_RS08720	COG1648	precorrin-2 dehydrogenase activity
KD35_RS08730	COG0733	neurotransmitter:sodium symporter activity
KD35_RS08750	COG1757	Na H antiporter
KD35_RS08765	COG4758	membrane
KD35_RS08770	COG4585	Histidine kinase
KD35_RS08775	COG2197	response regulator
KD35_RS08785	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS08795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KD35_RS08820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KD35_RS08820	COG1017	nitric oxide dioxygenase activity
KD35_RS08840	COG0730	response to heat
KD35_RS08845	COG0306	phosphate transporter
KD35_RS08850	COG1392	Phosphate transport regulator
KD35_RS08855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_RS08870	COG3852	Histidine kinase
KD35_RS08875	COG1801	Protein of unknown function DUF72
KD35_RS08885	COG0582	viral genome integration into host DNA
KD35_RS08890	COG5002	protein histidine kinase activity
KD35_RS08910	COG0392	lysyltransferase activity
KD35_RS08910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KD35_RS08925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_RS08930	COG1686	Belongs to the peptidase S11 family
KD35_RS08935	COG2715	membrane protein required for spore maturation
KD35_RS08940	COG0700	Nucleoside recognition
KD35_RS08945	COG1187	pseudouridine synthase activity
KD35_RS08955	COG1333	cytochrome c biogenesis protein
KD35_RS08960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KD35_RS08965	COG0745	RESPONSE REGULATOR receiver
KD35_RS08970	COG5002	protein histidine kinase activity
KD35_RS08975	COG2096	Adenosyltransferase
KD35_RS08990	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KD35_RS08995	COG1141	Ferredoxin
KD35_RS09000	COG4955	Helix-turn-helix domain
KD35_RS09005	COG0514	ATP-dependent DNA helicase (RecQ)
KD35_RS09010	COG1266	CAAX protease self-immunity
KD35_RS09030	COG4862	establishment of competence for transformation
KD35_RS09035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KD35_RS09055	COG0492	ferredoxin-NADP+ reductase activity
KD35_RS09060	COG0252	asparaginase activity
KD35_RS09130	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_RS09145	COG0142	geranyltranstransferase activity
KD35_RS09155	COG0142	geranyltranstransferase activity
KD35_RS09175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KD35_RS09180	COG0457	Tetratricopeptide repeat
KD35_RS09200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KD35_RS09210	COG4347	Protein of unknown function (DUF1405)
KD35_RS09225	COG2738	Putative neutral zinc metallopeptidase
KD35_RS09235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS09240	COG1694	Mazg nucleotide pyrophosphohydrolase
KD35_RS09255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_RS09260	COG0438	transferase activity, transferring glycosyl groups
KD35_RS09300	COG1199	ATP-dependent helicase activity
KD35_RS09300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KD35_RS09320	COG3935	DnaD domain protein
KD35_RS09325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KD35_RS09385	COG0116	Belongs to the methyltransferase superfamily
KD35_RS09395	COG1199	ATP-dependent helicase activity
KD35_RS09400	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KD35_RS09410	COG3173	Aminoglycoside phosphotransferase
KD35_RS09415	COG0024	Methionine aminopeptidase
KD35_RS09425	COG2233	PERMEase
KD35_RS09430	COG2311	Membrane
KD35_RS09435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_RS09445	COG0456	acetyltransferase
KD35_RS09470	COG0754	glutathionylspermidine amidase activity
KD35_RS09485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_RS09510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KD35_RS09525	COG1215	transferase activity, transferring glycosyl groups
KD35_RS09530	COG0438	transferase activity, transferring glycosyl groups
KD35_RS09545	COG0454	-acetyltransferase
KD35_RS09565	COG0328	RNA-DNA hybrid ribonuclease activity
KD35_RS09605	COG1280	lysine exporter protein (LysE YggA)
KD35_RS09620	COG3162	membrane
KD35_RS09630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_RS09640	COG0475	glutathione-regulated potassium exporter activity
KD35_RS09645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_RS09650	COG0789	Transcriptional regulator
KD35_RS09650	COG4978	Transcriptional regulator
KD35_RS09660	COG2323	membrane
KD35_RS09665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KD35_RS09720	COG1923	regulation of RNA biosynthetic process
KD35_RS09730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KD35_RS09735	COG1360	Flagellar Motor Protein
KD35_RS09740	COG2201	protein-glutamate methylesterase activity
KD35_RS09750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_RS09750	COG1776	CheC inhibitor of MCP methylation
KD35_RS09765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KD35_RS09785	COG1256	bacterial-type flagellum assembly
KD35_RS09790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KD35_RS09815	COG1815	bacterial-type flagellum-dependent cell motility
KD35_RS09820	COG1558	bacterial-type flagellum-dependent cell motility
KD35_RS09830	COG1766	The M ring may be actively involved in energy transduction
KD35_RS09840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_RS09850	COG1157	protein secretion by the type III secretion system
KD35_RS09890	COG0784	Response regulator, receiver
KD35_RS09890	COG0835	chemotaxis
KD35_RS09900	COG0463	Glycosyl transferase, family 2
KD35_RS09930	COG0457	Tetratricopeptide repeat
KD35_RS09930	COG0463	Glycosyl transferase, family 2
KD35_RS09955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KD35_RS09960	COG0741	lytic transglycosylase activity
KD35_RS09975	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_RS09975	COG1776	CheC inhibitor of MCP methylation
KD35_RS09985	COG1338	Plays a role in the flagellum-specific transport system
KD35_RS09990	COG1987	bacterial-type flagellum assembly
KD35_RS10000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KD35_RS10005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KD35_RS10010	COG1419	protein localization to endoplasmic reticulum
KD35_RS10015	COG4786	Flagellar basal body rod
KD35_RS10020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_RS10045	COG1309	transcriptional regulator
KD35_RS10065	COG2329	Antibiotic biosynthesis monooxygenase
KD35_RS10090	COG0583	DNA-binding transcription factor activity
KD35_RS10095	COG3842	ATPase activity
KD35_RS10100	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_RS10110	COG1234	tRNA 3'-trailer cleavage
KD35_RS10135	COG1686	Belongs to the peptidase S11 family
KD35_RS10145	COG0406	alpha-ribazole phosphatase activity
KD35_RS10190	COG2733	membrane
KD35_RS10225	COG1131	(ABC) transporter
KD35_RS10240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_RS10245	COG0528	UMP kinase activity
KD35_RS10255	COG1027	Aspartate ammonia-lyase
KD35_RS10260	COG0281	malic enzyme
KD35_RS10265	COG4191	Histidine kinase
KD35_RS10270	COG0784	Response regulator, receiver
KD35_RS10275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_RS10335	COG1051	belongs to the nudix hydrolase family
KD35_RS10340	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_RS10350	COG2814	Major facilitator Superfamily
KD35_RS10365	COG1966	Carbon starvation protein
KD35_RS10380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS10390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KD35_RS10400	COG4166	transmembrane transport
KD35_RS10405	COG2223	nitrite transmembrane transporter activity
KD35_RS10410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_RS10425	COG2244	polysaccharide biosynthetic process
KD35_RS10430	COG0733	neurotransmitter:sodium symporter activity
KD35_RS10440	COG5566	PFAM Mor transcription activator
KD35_RS10445	COG2323	membrane
KD35_RS10460	COG2084	Dehydrogenase
KD35_RS10475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_RS10485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_RS10490	COG0028	Belongs to the TPP enzyme family
KD35_RS10495	COG0440	acetolactate synthase activity
KD35_RS10500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KD35_RS10510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KD35_RS10535	COG2814	Major facilitator Superfamily
KD35_RS10540	COG3384	dioxygenase
KD35_RS10550	COG3279	Response regulator of the LytR AlgR family
KD35_RS10555	COG0427	acetyl-CoA hydrolase
KD35_RS10575	COG1073	alpha beta
KD35_RS10580	COG4166	transmembrane transport
KD35_RS10605	COG0535	radical SAM domain protein
KD35_RS10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS10630	COG1914	H( )-stimulated, divalent metal cation uptake system
KD35_RS10645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KD35_RS10680	COG2390	Transcriptional regulator
KD35_RS10690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS10695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KD35_RS10710	COG4224	UPF0291 protein
KD35_RS10730	COG0006	proline dipeptidase activity
KD35_RS10735	COG2132	Multicopper oxidase
KD35_RS10750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KD35_RS10765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_RS10780	COG2372	response to copper ion
KD35_RS10780	COG1276	copper resistance
KD35_RS10785	COG4549	nuclear export factor GLE1
KD35_RS10795	COG0697	spore germination
KD35_RS10800	COG0583	DNA-binding transcription factor activity
KD35_RS10805	COG1959	2 iron, 2 sulfur cluster binding
KD35_RS10810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KD35_RS10815	COG0778	Nitroreductase
KD35_RS10830	COG0628	permease
KD35_RS10840	COG1231	oxidoreductase activity
KD35_RS10845	COG0523	cobalamin synthesis protein
KD35_RS10860	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS10865	COG2030	dehydratase
KD35_RS10870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS10880	COG0411	ABC transporter
KD35_RS10900	COG0583	DNA-binding transcription factor activity
KD35_RS10920	COG1846	Transcriptional regulator
KD35_RS10930	COG1271	oxidase subunit
KD35_RS10935	COG1294	oxidase, subunit
KD35_RS10940	COG4988	ABC transporter
KD35_RS10945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KD35_RS10965	COG1686	Belongs to the peptidase S11 family
KD35_RS10980	COG0791	NLP P60 protein
KD35_RS10980	COG1388	LysM domain
KD35_RS10990	COG1132	(ABC) transporter
KD35_RS10995	COG1132	(ABC) transporter
KD35_RS11000	COG0745	RESPONSE REGULATOR receiver
KD35_RS11005	COG5002	protein histidine kinase activity
KD35_RS11015	COG0300	oxidoreductase activity
KD35_RS11050	COG0460	homoserine dehydrogenase
KD35_RS11075	COG1316	TRANSCRIPTIONal
KD35_RS11085	COG0745	RESPONSE REGULATOR receiver
KD35_RS11090	COG5002	protein histidine kinase activity
KD35_RS11105	COG1285	pathogenesis
KD35_RS11110	COG1247	-acetyltransferase
KD35_RS11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KD35_RS11140	COG1082	Xylose isomerase domain protein TIM barrel
KD35_RS11155	COG1279	arginine transmembrane transporter activity
KD35_RS11165	COG1752	Esterase of the alpha-beta hydrolase superfamily
KD35_RS11205	COG2002	toxin-antitoxin pair type II binding
KD35_RS11210	COG1404	Belongs to the peptidase S8 family
KD35_RS11215	COG0640	Transcriptional regulator
KD35_RS11220	COG0667	Aldo Keto reductase
KD35_RS11225	COG2814	Major facilitator Superfamily
KD35_RS11250	COG0840	transmembrane signaling receptor activity
KD35_RS11270	COG3949	Membrane
KD35_RS11275	COG0783	Belongs to the Dps family
KD35_RS11290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_RS11300	COG1231	oxidoreductase activity
KD35_RS11310	COG4989	oxidoreductase activity
KD35_RS11315	COG0523	cobalamin synthesis protein
KD35_RS11320	COG0456	acetyltransferase
KD35_RS11380	COG0803	Belongs to the bacterial solute-binding protein 9 family
KD35_RS11380	COG3443	Belongs to the bacterial solute-binding protein 9 family
KD35_RS11390	COG0702	epimerase
KD35_RS11400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KD35_RS11410	COG4166	transmembrane transport
KD35_RS11425	COG0406	alpha-ribazole phosphatase activity
KD35_RS11435	COG5337	Spore coat protein CotH
KD35_RS11440	COG1051	belongs to the nudix hydrolase family
KD35_RS11445	COG0586	Pfam SNARE associated Golgi protein
KD35_RS11450	COG2244	polysaccharide biosynthetic process
KD35_RS11460	COG0701	Predicted permease
KD35_RS11465	COG3689	TIGRFAM TIGR03943 family protein
KD35_RS11470	COG1607	acyl-coa hydrolase
KD35_RS11475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_RS11490	COG0702	epimerase
KD35_RS11495	COG2839	Protein conserved in bacteria
KD35_RS11500	COG1253	flavin adenine dinucleotide binding
KD35_RS11515	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS11520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_RS11540	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_RS11550	COG1876	peptidase activity
KD35_RS11560	COG0154	amidase activity
KD35_RS11565	COG2211	Major facilitator Superfamily
KD35_RS11585	COG0561	phosphatase activity
KD35_RS11595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KD35_RS11600	COG4106	trans-aconitate 2-methyltransferase activity
KD35_RS11615	COG1819	glycosyl
KD35_RS11620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS11625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS11650	COG0456	acetyltransferase
KD35_RS11700	COG3874	Sporulation protein YtfJ
KD35_RS11725	COG2226	methyltransferase
KD35_RS11745	COG1082	Xylose isomerase domain protein TIM barrel
KD35_RS11750	COG0346	lactoylglutathione lyase activity
KD35_RS11760	COG0604	alcohol dehydrogenase
KD35_RS11765	COG1595	DNA-templated transcription, initiation
KD35_RS11790	COG0386	Belongs to the glutathione peroxidase family
KD35_RS11795	COG1305	Transglutaminase-like
KD35_RS11800	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KD35_RS11805	COG0714	Associated with various cellular activities
KD35_RS11820	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KD35_RS11825	COG1140	nitrate reductase beta subunit
KD35_RS11830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KD35_RS11835	COG2181	nitrate reductase activity
KD35_RS11855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KD35_RS11860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KD35_RS11865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_RS11870	COG0303	'Molybdopterin
KD35_RS11875	COG0314	molybdopterin synthase activity
KD35_RS11885	COG2223	nitrite transmembrane transporter activity
KD35_RS11900	COG1648	precorrin-2 dehydrogenase activity
KD35_RS11910	COG1587	Uroporphyrinogen-III synthase
KD35_RS11910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KD35_RS11915	COG2146	nitrite reductase [NAD(P)H] activity
KD35_RS11920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KD35_RS11925	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KD35_RS11960	COG2359	stage V sporulation protein S
KD35_RS11975	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_RS11990	COG1418	mRNA catabolic process
KD35_RS11995	COG0488	(ABC) transporter
KD35_RS12010	COG0629	single-stranded DNA binding
KD35_RS12025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KD35_RS12030	COG1413	lyase activity
KD35_RS12045	COG2521	methyltransferase
KD35_RS12045	COG2136	Putative SAM-dependent methyltransferase
KD35_RS12050	COG0018	arginyl-trna synthetase
KD35_RS12075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KD35_RS12090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KD35_RS12095	COG0017	Asparaginyl-tRNA synthetase
KD35_RS12115	COG1674	ftsk spoiiie
KD35_RS12210	COG1929	Belongs to the glycerate kinase type-1 family
KD35_RS12215	COG0471	metal ion transport
KD35_RS12220	COG0745	RESPONSE REGULATOR receiver
KD35_RS12225	COG5002	protein histidine kinase activity
KD35_RS12225	COG3850	Histidine kinase
KD35_RS12240	COG0733	neurotransmitter:sodium symporter activity
KD35_RS12265	COG2610	gluconate transmembrane transporter activity
KD35_RS12270	COG1454	alcohol dehydrogenase
KD35_RS12275	COG1794	racemase activity, acting on amino acids and derivatives
KD35_RS12285	COG0456	acetyltransferase
KD35_RS12300	COG1131	(ABC) transporter
KD35_RS12305	COG4473	ABC transporter
KD35_RS12315	COG0546	phosphoglycolate phosphatase activity
KD35_RS12335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_RS12350	COG0768	penicillin binding
KD35_RS12355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_RS12360	COG0204	Acyl-transferase
KD35_RS12365	COG1272	protein, Hemolysin III
KD35_RS12375	COG0805	protein transport
KD35_RS12385	COG1307	EDD domain protein, DegV family
KD35_RS12390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KD35_RS12395	COG1999	signal sequence binding
KD35_RS12400	COG0071	Belongs to the small heat shock protein (HSP20) family
KD35_RS12405	COG0367	asparagine synthase
KD35_RS12425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS12430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_RS12465	COG0668	transmembrane transport
KD35_RS12470	COG2203	Gaf domain
KD35_RS12470	COG4585	Histidine kinase
KD35_RS12475	COG2197	response regulator
KD35_RS12485	COG1737	Transcriptional regulator
KD35_RS12490	COG1064	alcohol dehydrogenase
KD35_RS12520	COG1070	Carbohydrate kinase
KD35_RS12525	COG1070	Carbohydrate kinase
KD35_RS12555	COG1125	glycine betaine transport
KD35_RS12555	COG0517	IMP dehydrogenase activity
KD35_RS12560	COG1174	glycine betaine transport
KD35_RS12595	COG1253	flavin adenine dinucleotide binding
KD35_RS12600	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS12605	COG5506	Protein of unknown function (DUF1694)
KD35_RS12620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_RS12625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KD35_RS12630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KD35_RS12635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_RS12640	COG0456	acetyltransferase
KD35_RS12645	COG3829	transcription factor binding
KD35_RS12650	COG1509	lysine 2,3-aminomutase activity
KD35_RS12690	COG4326	sporulation control protein
KD35_RS12695	COG0671	phosphoesterase, PA-phosphatase related
KD35_RS12700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KD35_RS12705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_RS12735	COG1715	Restriction endonuclease
KD35_RS12735	COG1787	Restriction endonuclease
KD35_RS12825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_RS12865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_RS12865	COG4499	WXG100 protein secretion system (Wss), protein YukC
KD35_RS12870	COG2814	Major facilitator Superfamily
KD35_RS12875	COG4841	protein insertion into membrane
KD35_RS12880	COG0372	Belongs to the citrate synthase family
KD35_RS12885	COG2079	MmgE PrpD family protein
KD35_RS12890	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KD35_RS12895	COG1960	acyl-CoA dehydrogenase activity
KD35_RS12900	COG2084	Dehydrogenase
KD35_RS12910	COG1280	lysine exporter protein (LysE YggA)
KD35_RS12915	COG1024	Enoyl-CoA hydratase
KD35_RS12930	COG0420	3'-5' exonuclease activity
KD35_RS12935	COG0419	ATPase involved in DNA repair
KD35_RS12965	COG2223	nitrite transmembrane transporter activity
KD35_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS12975	COG1169	isochorismate synthase
KD35_RS12980	COG1021	2,3-dihydroxybenzoate-AMP ligase
KD35_RS12985	COG3433	isochorismatase activity
KD35_RS12985	COG1535	isochorismatase
KD35_RS12990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KD35_RS12995	COG3251	PFAM MbtH domain protein
KD35_RS13000	COG2814	Major facilitator Superfamily
KD35_RS13015	COG0776	regulation of translation
KD35_RS13025	COG2318	DinB family
KD35_RS13035	COG1115	amino acid carrier protein
KD35_RS13055	COG2329	Antibiotic biosynthesis monooxygenase
KD35_RS13060	COG1187	pseudouridine synthase activity
KD35_RS13065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_RS13080	COG0596	Alpha beta hydrolase
KD35_RS13085	COG2814	Major facilitator Superfamily
KD35_RS13105	COG2226	methyltransferase
KD35_RS13150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS13185	COG1247	-acetyltransferase
KD35_RS13215	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KD35_RS13225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS13235	COG1278	Cold shock
KD35_RS13250	COG0010	Belongs to the arginase family
KD35_RS13255	COG0561	phosphatase activity
KD35_RS13300	COG0583	DNA-binding transcription factor activity
KD35_RS13305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KD35_RS13320	COG0583	DNA-binding transcription factor activity
KD35_RS13325	COG2258	MOSC domain
KD35_RS13340	COG1132	(ABC) transporter
KD35_RS13345	COG1132	(ABC) transporter
KD35_RS13365	COG1396	sequence-specific DNA binding
KD35_RS13390	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KD35_RS13395	COG1595	DNA-templated transcription, initiation
KD35_RS13420	COG1649	PFAM Uncharacterised BCR, COG1649
KD35_RS13445	COG2971	BadF BadG BcrA BcrD
KD35_RS13450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_RS13455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KD35_RS13475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS13505	COG1309	transcriptional regulator
KD35_RS13520	COG1136	(ABC) transporter
KD35_RS13520	COG0577	efflux transmembrane transporter activity
KD35_RS13525	COG3615	Tellurite resistance protein tehB
KD35_RS13525	COG0500	methyltransferase
KD35_RS13535	COG2226	methyltransferase
KD35_RS13540	COG3961	Belongs to the TPP enzyme family
KD35_RS13545	COG1846	Transcriptional regulator
KD35_RS13585	COG2195	Cleaves the N-terminal amino acid of tripeptides
KD35_RS13600	COG1595	DNA-templated transcription, initiation
KD35_RS13610	COG0768	penicillin binding
KD35_RS13620	COG2367	Beta-lactamase
KD35_RS13625	COG0671	phosphoesterase, PA-phosphatase related
KD35_RS13630	COG1609	Transcriptional regulator
KD35_RS13635	COG2814	Major facilitator Superfamily
KD35_RS13640	COG0673	inositol 2-dehydrogenase activity
KD35_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS13665	COG0191	fructose-bisphosphate aldolase activity
KD35_RS13670	COG3718	enzyme involved in inositol metabolism
KD35_RS13700	COG0457	Tetratricopeptide repeat
KD35_RS13705	COG1476	TRANSCRIPTIONal
KD35_RS13720	COG1876	peptidase activity
KD35_RS13740	COG1309	transcriptional regulator
KD35_RS13745	COG0488	(ABC) transporter
KD35_RS13760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS13770	COG1252	NADH dehydrogenase
KD35_RS13775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS13790	COG1131	(ABC) transporter
KD35_RS13800	COG1309	transcriptional regulator
KD35_RS13815	COG1960	acyl-CoA dehydrogenase activity
KD35_RS13820	COG0439	Biotin carboxylase
KD35_RS13825	COG0511	ligase activity, forming carbon-carbon bonds
KD35_RS13830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KD35_RS13835	COG1024	Enoyl-CoA hydratase
KD35_RS13840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KD35_RS13845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_RS13855	COG1247	-acetyltransferase
KD35_RS13860	COG0572	uridine kinase
KD35_RS13870	COG2318	DinB family
KD35_RS13875	COG1686	Belongs to the peptidase S11 family
KD35_RS13900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KD35_RS13940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_RS13940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_RS13965	COG2814	Major facilitator Superfamily
KD35_RS13985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_RS14005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS14020	COG1063	alcohol dehydrogenase
KD35_RS14035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_RS14040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_RS14055	COG3773	Cell wall hydrolase
KD35_RS14065	COG0745	RESPONSE REGULATOR receiver
KD35_RS14080	COG0488	(ABC) transporter
KD35_RS14095	COG1136	(ABC) transporter
KD35_RS14120	COG0460	homoserine dehydrogenase
KD35_RS14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS14135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KD35_RS14210	COG2124	cytochrome p450
KD35_RS14245	COG0561	phosphatase activity
KD35_RS14255	COG5002	protein histidine kinase activity
KD35_RS14260	COG0768	penicillin binding
KD35_RS14265	COG1819	glycosyl
KD35_RS14270	COG1794	racemase activity, acting on amino acids and derivatives
KD35_RS14280	COG1122	ATPase activity
KD35_RS14290	COG2205	protein histidine kinase activity
KD35_RS14300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_RS14305	COG0604	alcohol dehydrogenase
KD35_RS14310	COG0768	penicillin binding
KD35_RS14320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_RS14355	COG0693	protein deglycase activity
KD35_RS14385	COG2814	Major facilitator Superfamily
KD35_RS14400	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_RS14420	COG0697	spore germination
KD35_RS14445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_RS14455	COG2223	nitrite transmembrane transporter activity
KD35_RS14470	COG2816	NAD+ diphosphatase activity
KD35_RS14475	COG0592	DNA-directed DNA polymerase activity
KD35_RS14480	COG1051	belongs to the nudix hydrolase family
KD35_RS14515	COG3878	Protein conserved in bacteria
KD35_RS14545	COG4667	esterase of the alpha-beta hydrolase superfamily
KD35_RS14570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KD35_RS14585	COG0322	excinuclease ABC activity
KD35_RS14625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_RS14650	COG1011	Hydrolase
KD35_RS14670	COG0076	glutamate decarboxylase activity
KD35_RS14685	COG1523	belongs to the glycosyl hydrolase 13 family
KD35_RS14690	COG3227	Zinc metalloprotease (Elastase)
KD35_RS14710	COG0201	protein transport
KD35_RS14720	COG0697	spore germination
KD35_RS14725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS14755	COG4129	membrane
KD35_RS14760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS14775	COG2959	enzyme of heme biosynthesis
KD35_RS14795	COG3483	tryptophan 2,3-dioxygenase activity
KD35_RS14800	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KD35_RS14805	COG3844	kynureninase activity
KD35_RS14810	COG1309	transcriptional regulator
KD35_RS14840	COG3284	Transcriptional regulator
KD35_RS14860	COG1349	DNA-binding transcription factor activity
KD35_RS14880	COG1959	2 iron, 2 sulfur cluster binding
KD35_RS14895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KD35_RS14900	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_RS14905	COG0022	dehydrogenase e1 component
KD35_RS14910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS14925	COG0456	acetyltransferase
KD35_RS14925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_RS14960	COG4176	ABC-type proline glycine betaine transport system permease component
KD35_RS14965	COG4175	Glycine betaine
KD35_RS14965	COG0517	IMP dehydrogenase activity
KD35_RS14990	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KD35_RS14995	COG2153	protein acetylation
KD35_RS15000	COG3397	chitin binding
KD35_RS15015	COG2205	protein histidine kinase activity
KD35_RS15045	COG2333	competence protein COMEC
KD35_RS15045	COG0658	competence protein
KD35_RS15095	COG3973	AAA domain
KD35_RS15110	COG2105	PFAM AIG2 family protein
KD35_RS15115	COG0514	ATP-dependent DNA helicase (RecQ)
KD35_RS15145	COG4637	Psort location Cytoplasmic, score
KD35_RS15170	COG3397	chitin binding
KD35_RS15180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KD35_RS15185	COG1115	amino acid carrier protein
KD35_RS15190	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS15195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KD35_RS15205	COG3938	Belongs to the proline racemase family
KD35_RS15210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_RS15250	COG0586	Pfam SNARE associated Golgi protein
KD35_RS15265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KD35_RS15270	COG0519	Catalyzes the synthesis of GMP from XMP
KD35_RS15275	COG4166	transmembrane transport
KD35_RS15285	COG4948	Mandelate Racemase Muconate Lactonizing
KD35_RS15325	COG2936	dipeptidyl-peptidase activity
KD35_RS15330	COG5002	protein histidine kinase activity
KD35_RS15335	COG0745	RESPONSE REGULATOR receiver
KD35_RS15375	COG1307	EDD domain protein, DegV family
KD35_RS15395	COG2814	Major facilitator Superfamily
KD35_RS15405	COG1664	Polymer-forming cytoskeletal
KD35_RS15410	COG0789	Transcriptional regulator
KD35_RS15415	COG4533	DNA binding
KD35_RS15420	COG0477	Major facilitator Superfamily
KD35_RS15420	COG2814	Major facilitator Superfamily
KD35_RS15440	COG2261	transglycosylase associated protein
KD35_RS15455	COG2226	methyltransferase
KD35_RS15490	COG0436	Aminotransferase
KD35_RS15495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KD35_RS15500	COG5146	pantothenate kinase activity
KD35_RS15520	COG1131	(ABC) transporter
KD35_RS15570	COG0628	permease
KD35_RS15585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_RS15595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_RS15600	COG1116	anion transmembrane transporter activity
KD35_RS15620	COG2816	NAD+ diphosphatase activity
KD35_RS15640	COG2746	aminoglycoside 3-N-acetyltransferase activity
KD35_RS15665	COG0697	spore germination
KD35_RS15670	COG2318	DinB family
KD35_RS15690	COG4912	Dna alkylation repair
KD35_RS15710	COG0861	Integral membrane protein TerC family
KD35_RS15715	COG1368	sulfuric ester hydrolase activity
KD35_RS15720	COG0488	(ABC) transporter
KD35_RS15730	COG2409	Drug exporters of the RND superfamily
KD35_RS15730	COG1033	growth of symbiont in host cell
KD35_RS15735	COG1033	growth of symbiont in host cell
KD35_RS15735	COG2409	Drug exporters of the RND superfamily
KD35_RS15740	COG2409	Drug exporters of the RND superfamily
KD35_RS15740	COG1033	growth of symbiont in host cell
KD35_RS15745	COG1309	transcriptional regulator
KD35_RS15760	COG0287	Prephenate dehydrogenase
KD35_RS15765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KD35_RS15770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KD35_RS15775	COG1605	Chorismate mutase
KD35_RS15775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KD35_RS15810	COG1388	LysM domain
KD35_RS15810	COG3584	3D domain protein
KD35_RS15820	COG1595	DNA-templated transcription, initiation
KD35_RS15845	COG1879	ABC-type sugar transport system periplasmic component
KD35_RS15855	COG1172	Belongs to the binding-protein-dependent transport system permease family
KD35_RS15865	COG2390	Transcriptional regulator
KD35_RS15900	COG2329	Antibiotic biosynthesis monooxygenase
KD35_RS15920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS15930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KD35_RS15935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_RS15940	COG4187	Peptidase family M20/M25/M40
KD35_RS15945	COG1414	Transcriptional regulator
KD35_RS15950	COG0833	amino acid
KD35_RS15955	COG1690	Belongs to the RtcB family
KD35_RS15960	COG3239	Fatty acid desaturase
KD35_RS15965	COG1785	Belongs to the alkaline phosphatase family
KD35_RS15975	COG3655	Transcriptional regulator
KD35_RS15990	COG4377	Putative membrane peptidase family (DUF2324)
KD35_RS16000	COG3279	Response regulator of the LytR AlgR family
KD35_RS16010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS16015	COG0346	lactoylglutathione lyase activity
KD35_RS16035	COG0714	Associated with various cellular activities
KD35_RS16085	COG0463	Glycosyl transferase, family 2
KD35_RS16095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KD35_RS16100	COG0753	catalase activity
KD35_RS16110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KD35_RS16135	COG0714	Associated with various cellular activities
KD35_RS16145	COG0778	Nitroreductase
KD35_RS16150	COG1846	Transcriptional regulator
KD35_RS16185	COG1725	Transcriptional regulator
KD35_RS16195	COG1136	(ABC) transporter
KD35_RS16195	COG0577	efflux transmembrane transporter activity
KD35_RS16220	COG2207	Transcriptional regulator
KD35_RS16225	COG0456	acetyltransferase
KD35_RS16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS16265	COG0642	Histidine kinase
KD35_RS16270	COG0745	RESPONSE REGULATOR receiver
KD35_RS16275	COG0596	Alpha beta hydrolase
KD35_RS16305	COG0730	response to heat
KD35_RS16315	COG0833	amino acid
KD35_RS16325	COG4335	DNA alkylation repair
KD35_RS16365	COG0768	penicillin binding
KD35_RS16375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KD35_RS16410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KD35_RS16415	COG1414	Transcriptional regulator
KD35_RS16430	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_RS16435	COG0640	Transcriptional regulator
KD35_RS16445	COG1960	acyl-CoA dehydrogenase activity
KD35_RS16465	COG3314	Sporulation integral membrane protein YlbJ
KD35_RS16480	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KD35_RS16495	COG0574	Belongs to the PEP-utilizing enzyme family
KD35_RS16495	COG3848	Pyruvate phosphate dikinase
KD35_RS16500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS16515	COG5577	PFAM Coat F domain
KD35_RS16520	COG3403	YqcI/YcgG family
KD35_RS16525	COG1280	lysine exporter protein (LysE YggA)
KD35_RS16560	COG1063	alcohol dehydrogenase
KD35_RS16575	COG1027	Aspartate ammonia-lyase
KD35_RS16580	COG0252	asparaginase activity
KD35_RS16585	COG1396	sequence-specific DNA binding
KD35_RS16595	COG0322	excinuclease ABC activity
KD35_RS16600	COG0531	amino acid
KD35_RS16605	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS16610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_RS16620	COG0281	malic enzyme
KD35_RS16640	COG0531	amino acid
KD35_RS16645	COG0697	spore germination
KD35_RS16650	COG0784	Response regulator, receiver
KD35_RS16660	COG2066	Belongs to the glutaminase family
KD35_RS16665	COG1115	amino acid carrier protein
KD35_RS16690	COG0737	Belongs to the 5'-nucleotidase family
KD35_RS16695	COG0753	catalase activity
KD35_RS16700	COG2267	carboxylic ester hydrolase activity
KD35_RS16705	COG1335	isochorismatase
KD35_RS16730	COG0583	DNA-binding transcription factor activity
KD35_RS16775	COG0415	Belongs to the DNA photolyase family
KD35_RS16780	COG0288	reversible hydration of carbon dioxide
KD35_RS16790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KD35_RS16795	COG5609	conserved protein (DUF2294)
KD35_RS16805	COG1575	Belongs to the MenA family. Type 1 subfamily
KD35_RS16810	COG2267	carboxylic ester hydrolase activity
KD35_RS16815	COG0803	Belongs to the bacterial solute-binding protein 9 family
KD35_RS16820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KD35_RS16825	COG1121	(ABC) transporter
KD35_RS16855	COG0798	PFAM Bile acid sodium symporter
KD35_RS16860	COG0346	lactoylglutathione lyase activity
KD35_RS16865	COG0640	Transcriptional regulator
KD35_RS16880	COG0443	Heat shock 70 kDa protein
KD35_RS16895	COG1522	sequence-specific DNA binding
KD35_RS16910	COG0346	lactoylglutathione lyase activity
KD35_RS16935	COG2169	Transcriptional regulator
KD35_RS16980	COG2814	Major facilitator Superfamily
KD35_RS17005	COG0745	RESPONSE REGULATOR receiver
KD35_RS17010	COG3850	Histidine kinase
KD35_RS17010	COG5002	protein histidine kinase activity
KD35_RS17040	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KD35_RS17065	COG1476	TRANSCRIPTIONal
KD35_RS17080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS17085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_RS17095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS17100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KD35_RS17115	COG1136	(ABC) transporter
KD35_RS17120	COG0577	efflux transmembrane transporter activity
KD35_RS17140	COG5002	protein histidine kinase activity
KD35_RS17140	COG3850	Histidine kinase
KD35_RS17150	COG2364	Membrane
KD35_RS17155	COG1846	Transcriptional regulator
KD35_RS17165	COG2808	Putative FMN-binding domain
KD35_RS17170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS17175	COG2271	Major facilitator Superfamily
KD35_RS17180	COG1556	Lactate utilization protein
KD35_RS17185	COG1139	Iron-sulfur cluster binding protein
KD35_RS17195	COG0583	DNA-binding transcription factor activity
KD35_RS17205	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_RS17230	COG0738	Major facilitator superfamily
KD35_RS17235	COG0673	inositol 2-dehydrogenase activity
KD35_RS17240	COG0561	phosphatase activity
KD35_RS17250	COG1609	Transcriptional regulator
KD35_RS17255	COG0457	Tetratricopeptide repeat
KD35_RS17275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KD35_RS17305	COG0534	Mate efflux family protein
KD35_RS17320	COG2814	Major facilitator Superfamily
KD35_RS17325	COG1309	transcriptional regulator
KD35_RS17340	COG0814	amino acid
KD35_RS17345	COG1760	l-serine dehydratase
KD35_RS17350	COG1760	l-serine dehydratase
KD35_RS17360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KD35_RS17365	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KD35_RS17375	COG1335	isochorismatase
KD35_RS17380	COG1522	sequence-specific DNA binding
KD35_RS17385	COG0531	amino acid
KD35_RS17400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KD35_RS17420	COG1595	DNA-templated transcription, initiation
KD35_RS17435	COG0662	Cupin 2, conserved barrel domain protein
KD35_RS17445	COG2207	Transcriptional regulator
KD35_RS17445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS17500	COG0477	Major facilitator Superfamily
KD35_RS17510	COG1846	Transcriptional regulator
KD35_RS17515	COG2814	Major facilitator Superfamily
KD35_RS17530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_RS17535	COG1131	(ABC) transporter
KD35_RS17555	COG2076	Multidrug Resistance protein
KD35_RS17560	COG1309	transcriptional regulator
KD35_RS17575	COG2031	fatty acid transporter
KD35_RS17585	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_RS17615	COG1122	ATPase activity
KD35_RS17620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KD35_RS17635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KD35_RS17640	COG1288	antiporter activity
KD35_RS17645	COG2356	endonuclease I
KD35_RS17660	COG3620	sequence-specific DNA binding
KD35_RS17665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_RS17670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KD35_RS17675	COG0124	histidyl-tRNA synthetase
KD35_RS17690	COG1733	regulation of RNA biosynthetic process
KD35_RS17695	COG0778	Nitroreductase
KD35_RS17715	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS17725	COG1131	(ABC) transporter
KD35_RS17750	COG1011	Hydrolase
KD35_RS17760	COG2365	Tyrosine phosphatase family
KD35_RS17785	COG0346	lactoylglutathione lyase activity
KD35_RS17790	COG1940	carbohydrate kinase activity
KD35_RS17795	COG0738	Major facilitator superfamily
KD35_RS17800	COG0110	maltose O-acetyltransferase activity
KD35_RS17810	COG1136	(ABC) transporter
KD35_RS17810	COG0577	efflux transmembrane transporter activity
KD35_RS17820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KD35_RS17825	COG0628	permease
KD35_RS17845	COG2226	methyltransferase
KD35_RS17855	COG0477	Major facilitator Superfamily
KD35_RS17885	COG1253	flavin adenine dinucleotide binding
KD35_RS17890	COG0789	Transcriptional regulator
KD35_RS17895	COG0697	spore germination
KD35_RS17900	COG1357	PFAM Pentapeptide repeats (8 copies)
KD35_RS17905	COG3813	Protein conserved in bacteria
KD35_RS17910	COG2706	6-phosphogluconolactonase activity
KD35_RS17915	COG1070	Carbohydrate kinase
KD35_RS17925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KD35_RS17930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KD35_RS17940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KD35_RS17945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KD35_RS17950	COG0604	alcohol dehydrogenase
KD35_RS17955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_RS17965	COG0604	alcohol dehydrogenase
KD35_RS17965	COG3321	synthase
KD35_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS18000	COG0656	L-ascorbic acid biosynthetic process
KD35_RS18005	COG2814	Major facilitator Superfamily
KD35_RS18020	COG0346	lactoylglutathione lyase activity
KD35_RS18025	COG0814	amino acid
KD35_RS18050	COG1393	Belongs to the ArsC family
KD35_RS18060	COG1733	regulation of RNA biosynthetic process
KD35_RS18065	COG2188	Transcriptional regulator
KD35_RS18075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KD35_RS18080	COG1733	regulation of RNA biosynthetic process
KD35_RS18085	COG1733	regulation of RNA biosynthetic process
KD35_RS18100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS18120	COG0384	phenazine biosynthesis protein PhzF
KD35_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS18150	COG1733	regulation of RNA biosynthetic process
KD35_RS18185	COG1191	sigma factor activity
KD35_RS18200	COG1309	transcriptional regulator
KD35_RS18220	COG3152	Membrane
KD35_RS18245	COG1151	hydroxylamine reductase activity
KD35_RS18255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS18260	COG3757	hydrolase, family 25
KD35_RS18260	COG3409	Peptidoglycan-binding domain 1 protein
KD35_RS18295	COG2072	flavoprotein involved in K transport
KD35_RS18330	COG0604	alcohol dehydrogenase
KD35_RS18335	COG1113	amino acid transport
KD35_RS18340	COG2814	Major facilitator Superfamily
KD35_RS18375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_RS18380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_RS18400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS18420	COG3739	integral membrane protein
KD35_RS18425	COG0384	phenazine biosynthesis protein PhzF
KD35_RS18455	COG0583	DNA-binding transcription factor activity
KD35_RS18475	COG1193	negative regulation of DNA recombination
KD35_RS18490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KD35_RS18500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_RS18530	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_RS18555	COG0640	Transcriptional regulator
KD35_RS18560	COG0604	alcohol dehydrogenase
KD35_RS18580	COG2808	Putative FMN-binding domain
KD35_RS18585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_RS18595	COG0385	Bile acid
KD35_RS18600	COG0277	FAD linked oxidase domain protein
KD35_RS18635	COG1216	Glycosyl transferase, family 2
KD35_RS18640	COG1024	Enoyl-CoA hydratase
KD35_RS18650	COG1285	pathogenesis
KD35_RS18660	COG2514	catechol 2,3-dioxygenase activity
KD35_RS18665	COG2720	vancomycin resistance protein
KD35_RS18705	COG0716	FMN binding
KD35_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS18745	COG0165	Argininosuccinate lyase
KD35_RS18760	COG4145	pantothenate transmembrane transporter activity
KD35_RS18770	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS18785	COG1657	PFAM Prenyltransferase squalene oxidase
KD35_RS18790	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KD35_RS18795	COG2962	Rard protein
KD35_RS18800	COG3326	Membrane
KD35_RS18815	COG0489	protein tyrosine kinase activity
KD35_RS18825	COG0314	molybdopterin synthase activity
KD35_RS18830	COG0303	'Molybdopterin
KD35_RS18835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_RS18840	COG2116	formate transmembrane transporter activity
KD35_RS18850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KD35_RS18855	COG5609	conserved protein (DUF2294)
KD35_RS18860	COG2427	Protein of unknown function (DUF1641)
KD35_RS18865	COG3383	formate dehydrogenase (NAD+) activity
KD35_RS18875	COG0697	spore germination
KD35_RS18915	COG2226	methyltransferase
KD35_RS18920	COG4166	transmembrane transport
KD35_RS18925	COG4166	transmembrane transport
KD35_RS18930	COG4166	transmembrane transport
KD35_RS18935	COG1301	dicarboxylic acid transport
KD35_RS18940	COG1316	TRANSCRIPTIONal
KD35_RS18950	COG1595	DNA-templated transcription, initiation
KD35_RS18975	COG1131	(ABC) transporter
KD35_RS18985	COG0673	inositol 2-dehydrogenase activity
KD35_RS18990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KD35_RS18995	COG0187	DNA topoisomerase II activity
KD35_RS19005	COG1832	CoA-binding protein
KD35_RS19010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_RS19015	COG0745	RESPONSE REGULATOR receiver
KD35_RS19030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_RS19035	COG4841	protein insertion into membrane
KD35_RS19040	COG0824	Thioesterase
KD35_RS19070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_RS19080	COG2274	protein secretion by the type I secretion system
KD35_RS19085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KD35_RS19115	COG2211	Major facilitator Superfamily
KD35_RS19125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_RS19140	COG0183	Belongs to the thiolase family
KD35_RS19145	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS19150	COG1268	BioY protein
KD35_RS19155	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS19200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS19210	COG5002	protein histidine kinase activity
KD35_RS19215	COG0400	carboxylic ester hydrolase activity
KD35_RS19220	COG0346	lactoylglutathione lyase activity
KD35_RS19225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_RS19230	COG0069	glutamate synthase activity
KD35_RS19235	COG1902	pentaerythritol trinitrate reductase activity
KD35_RS19240	COG1329	Transcriptional regulator
KD35_RS19245	COG0010	Belongs to the arginase family
KD35_RS19270	COG2226	methyltransferase
KD35_RS19325	COG4846	Membrane protein involved in cytochrome C biogenesis
KD35_RS19330	COG0785	Cytochrome C biogenesis protein
KD35_RS19340	COG0583	DNA-binding transcription factor activity
KD35_RS19345	COG1380	Effector of murein hydrolase LrgA
KD35_RS19350	COG1346	cytolysis
KD35_RS19365	COG0730	response to heat
KD35_RS19375	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_RS19375	COG3409	Peptidoglycan-binding domain 1 protein
KD35_RS19390	COG1132	(ABC) transporter
KD35_RS19395	COG1132	(ABC) transporter
KD35_RS19430	COG3639	organic phosphonate transmembrane transporter activity
KD35_RS19435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KD35_RS19450	COG0737	Belongs to the 5'-nucleotidase family
KD35_RS19460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KD35_RS19480	COG1695	Transcriptional regulator
KD35_RS19515	COG3409	Peptidoglycan-binding domain 1 protein
KD35_RS19515	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_RS19515	COG1388	LysM domain
KD35_RS19520	COG4824	toxin secretion phage lysis holin
KD35_RS19680	COG1595	DNA-templated transcription, initiation
KD35_RS19725	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KD35_RS19805	COG1396	sequence-specific DNA binding
KD35_RS19830	COG0174	glutamine synthetase
KD35_RS19835	COG0789	Transcriptional regulator
KD35_RS19840	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KD35_RS19850	COG2860	membrane
KD35_RS19855	COG0464	growth
KD35_RS19885	COG1388	LysM domain
KD35_RS19885	COG3584	3D domain protein
KD35_RS19890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_RS19890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KD35_RS19890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KD35_RS19895	COG1105	Belongs to the carbohydrate kinase PfkB family
KD35_RS19900	COG1349	DNA-binding transcription factor activity
KD35_RS19910	COG2322	membrane
KD35_RS19925	COG1113	amino acid transport
KD35_RS19935	COG1408	metallophosphoesterase
KD35_RS19940	COG2116	formate transmembrane transporter activity
KD35_RS19950	COG2217	Heavy metal translocating P-type atpase
KD35_RS19955	COG2608	mercury ion transmembrane transporter activity
KD35_RS19960	COG1937	Protein conserved in bacteria
KD35_RS19970	COG2819	hydrolase of the alpha beta superfamily
KD35_RS19975	COG1120	ATPase activity
KD35_RS19980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS19985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_RS19990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS20000	COG0708	Exodeoxyribonuclease III
KD35_RS20005	COG2169	Transcriptional regulator
KD35_RS20010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KD35_RS20015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KD35_RS20025	COG2364	Membrane
KD35_RS20040	COG2267	carboxylic ester hydrolase activity
KD35_RS20045	COG0346	lactoylglutathione lyase activity
KD35_RS20050	COG3300	MHYT domain
KD35_RS20050	COG5001	Diguanylate cyclase
KD35_RS20070	COG1346	cytolysis
KD35_RS20075	COG1380	Effector of murein hydrolase LrgA
KD35_RS20080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_RS20085	COG0596	Alpha beta hydrolase
KD35_RS20085	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_RS20090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_RS20105	COG1404	Belongs to the peptidase S8 family
KD35_RS20110	COG3773	Cell wall hydrolase
KD35_RS20115	COG0562	UDP-galactopyranose mutase
KD35_RS20120	COG1368	sulfuric ester hydrolase activity
KD35_RS20125	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_RS20135	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KD35_RS20160	COG1131	(ABC) transporter
KD35_RS20180	COG4550	Control of competence regulator ComK, YlbF/YmcA
KD35_RS20185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KD35_RS20190	COG1013	pyruvate-flavodoxin oxidoreductase activity
KD35_RS20195	COG0674	pyruvate-flavodoxin oxidoreductase activity
KD35_RS20195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KD35_RS20205	COG2359	stage V sporulation protein S
KD35_RS20210	COG1692	metallophosphoesterase
KD35_RS20235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KD35_RS20240	COG1426	Protein conserved in bacteria
KD35_RS20255	COG0300	oxidoreductase activity
KD35_RS20260	COG0612	Peptidase, M16
KD35_RS20265	COG0612	Peptidase, M16
KD35_RS20270	COG1079	Belongs to the binding-protein-dependent transport system permease family
KD35_RS20275	COG4603	Belongs to the binding-protein-dependent transport system permease family
KD35_RS20280	COG4603	Belongs to the binding-protein-dependent transport system permease family
KD35_RS20285	COG3845	ABC transporter
KD35_RS20290	COG1744	ABC transporter substrate-binding protein PnrA-like
KD35_RS20295	COG2188	Transcriptional regulator
KD35_RS20300	COG1674	ftsk spoiiie
KD35_RS20310	COG0740	serine-type endopeptidase activity
KD35_RS20315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_RS20330	COG0527	aspartate kinase activity
KD35_RS20335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KD35_RS20340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KD35_RS20345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KD35_RS20350	COG1873	PFAM PRC-barrel domain
KD35_RS20355	COG0612	Peptidase, M16
KD35_RS20360	COG0726	polysaccharide deacetylase
KD35_RS20375	COG0196	riboflavin kinase activity
KD35_RS20380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KD35_RS20390	COG1550	Protein conserved in bacteria
KD35_RS20400	COG1358	cellular component organization or biogenesis
KD35_RS20405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KD35_RS20410	COG0195	Participates in both transcription termination and antitermination
KD35_RS20430	COG0750	zinc metalloprotease
KD35_RS20440	COG4589	Belongs to the CDS family
KD35_RS20445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KD35_RS20455	COG0528	UMP kinase activity
KD35_RS20485	COG4974	Belongs to the 'phage' integrase family
KD35_RS20495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KD35_RS20505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KD35_RS20545	COG1837	Belongs to the UPF0109 family
KD35_RS20555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KD35_RS20565	COG0552	protein localization to endoplasmic reticulum
KD35_RS20570	COG1196	nuclear chromosome segregation
KD35_RS20580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KD35_RS20585	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS20590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KD35_RS20605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KD35_RS20610	COG1461	Dihydroxyacetone kinase
KD35_RS20615	COG1302	Protein conserved in bacteria
KD35_RS20630	COG1564	THIamine pyrophosphokinase
KD35_RS20635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KD35_RS20640	COG1162	GTPase activity
KD35_RS20645	COG2815	serine threonine protein kinase
KD35_RS20645	COG0515	serine threonine protein kinase
KD35_RS20650	COG0631	protein serine/threonine phosphatase activity
KD35_RS20660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KD35_RS20660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KD35_RS20670	COG0242	peptide deformylase activity
KD35_RS20675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KD35_RS20680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KD35_RS20700	COG1561	YicC-like family, N-terminal region
KD35_RS20705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KD35_RS20715	COG0006	proline dipeptidase activity
KD35_RS20730	COG3069	C4-dicarboxylate transmembrane transporter activity
KD35_RS20795	COG0564	pseudouridine synthase activity
KD35_RS20815	COG3599	regulation of cell shape
KD35_RS20820	COG2302	S4 RNA-binding domain
KD35_RS20825	COG0762	integral membrane protein
KD35_RS20835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KD35_RS20840	COG1496	oxidoreductase activity
KD35_RS20845	COG1873	PFAM PRC-barrel domain
KD35_RS20850	COG1191	sigma factor activity
KD35_RS20855	COG1191	sigma factor activity
KD35_RS20865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KD35_RS20870	COG0849	cell division
KD35_RS20875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KD35_RS20880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KD35_RS20890	COG0772	Belongs to the SEDS family
KD35_RS20905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_RS20910	COG0768	penicillin binding
KD35_RS20915	COG0768	penicillin binding
KD35_RS20920	COG4839	cell division protein FtsL
KD35_RS20935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KD35_RS20950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KD35_RS20955	COG1399	metal-binding, possibly nucleic acid-binding protein
KD35_RS21005	COG4824	toxin secretion phage lysis holin
KD35_RS21100	COG1802	Transcriptional regulator
KD35_RS21100	COG4626	Terminase
KD35_RS21125	COG0582	viral genome integration into host DNA
KD35_RS21195	COG0756	dUTP diphosphatase activity
KD35_RS21205	COG1191	sigma factor activity
KD35_RS21230	COG1484	DNA-dependent DNA replication
KD35_RS21260	COG1396	sequence-specific DNA binding
KD35_RS21270	COG1396	sequence-specific DNA binding
KD35_RS21285	COG0582	viral genome integration into host DNA
KD35_RS21295	COG3480	Lon protease (S16) C-terminal proteolytic domain
KD35_RS21300	COG1752	Esterase of the alpha-beta hydrolase superfamily
KD35_RS21305	COG3314	Sporulation integral membrane protein YlbJ
KD35_RS21315	COG0742	ribosomal rna small subunit methyltransferase
KD35_RS21330	COG3679	Belongs to the UPF0342 family
KD35_RS21335	COG0406	alpha-ribazole phosphatase activity
KD35_RS21350	COG2340	Cysteine-rich secretory protein family
KD35_RS21365	COG3336	cytochrome c oxidase
KD35_RS21400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KD35_RS21405	COG0772	Belongs to the SEDS family
KD35_RS21415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KD35_RS21420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KD35_RS21430	COG4896	Protein conserved in bacteria
KD35_RS21445	COG1217	gtp-binding protein TYPA
KD35_RS21455	COG0483	inositol monophosphate 1-phosphatase activity
KD35_RS21475	COG1982	Orn Lys Arg decarboxylase major
KD35_RS21520	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_RS21525	COG0022	dehydrogenase e1 component
KD35_RS21530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_RS21540	COG0242	peptide deformylase activity
KD35_RS21545	COG0561	phosphatase activity
KD35_RS21555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_RS21560	COG0569	domain protein
KD35_RS21580	COG0583	DNA-binding transcription factor activity
KD35_RS21585	COG0517	IMP dehydrogenase activity
KD35_RS21595	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KD35_RS21605	COG4703	Protein of unknown function (DUF1797)
KD35_RS21620	COG2200	EAL domain
KD35_RS21625	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS21630	COG1408	metallophosphoesterase
KD35_RS21640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KD35_RS21680	COG2814	Major facilitator Superfamily
KD35_RS21705	COG3209	COG3209 Rhs family protein
KD35_RS21715	COG2205	protein histidine kinase activity
KD35_RS21725	COG0436	Aminotransferase
KD35_RS21730	COG1609	Transcriptional regulator
KD35_RS21735	COG3833	ABC-type maltose transport systems, permease component
KD35_RS21740	COG1175	transmembrane transport
KD35_RS21745	COG2182	Extracellular solute-binding protein
KD35_RS21755	COG0366	Alpha amylase catalytic
KD35_RS21760	COG3842	ATPase activity
KD35_RS21800	COG0183	Belongs to the thiolase family
KD35_RS21840	COG1695	Transcriptional regulator
KD35_RS21845	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS21855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KD35_RS21865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KD35_RS21870	COG0436	Aminotransferase
KD35_RS21890	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KD35_RS21910	COG2199	diguanylate cyclase activity
KD35_RS21915	COG0778	Nitroreductase
KD35_RS21940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_RS21940	COG2190	(PTS) system
KD35_RS21940	COG1263	PTS System
KD35_RS21945	COG3711	transcriptional antiterminator
KD35_RS21955	COG2188	Transcriptional regulator
KD35_RS21965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KD35_RS21995	COG1547	Domain of unknown function (DUF309)
KD35_RS22000	COG0456	acetyltransferase
KD35_RS22010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KD35_RS22015	COG4086	secreted protein
KD35_RS22020	COG0561	phosphatase activity
KD35_RS22025	COG0697	spore germination
KD35_RS22040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS22065	COG0733	neurotransmitter:sodium symporter activity
KD35_RS22085	COG1686	Belongs to the peptidase S11 family
KD35_RS22090	COG1725	Transcriptional regulator
KD35_RS22095	COG1131	(ABC) transporter
KD35_RS22115	COG1846	Transcriptional regulator
KD35_RS22130	COG0598	Magnesium transport protein CorA
KD35_RS22155	COG4974	Belongs to the 'phage' integrase family
KD35_RS22165	COG0735	belongs to the Fur family
KD35_RS22170	COG1300	Membrane
KD35_RS22190	COG0667	Aldo Keto reductase
KD35_RS22195	COG0656	L-ascorbic acid biosynthetic process
KD35_RS22200	COG0456	acetyltransferase
KD35_RS22200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_RS22210	COG0737	Belongs to the 5'-nucleotidase family
KD35_RS22210	COG1525	nuclease
KD35_RS22210	COG4085	toxin activity
KD35_RS22220	COG0596	Alpha beta hydrolase
KD35_RS22225	COG2056	Na+-H+ antiporter family
KD35_RS22230	COG1609	Transcriptional regulator
KD35_RS22235	COG0456	acetyltransferase
KD35_RS22240	COG1073	alpha beta
KD35_RS22255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KD35_RS22255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KD35_RS22260	COG0307	riboflavin synthase, alpha
KD35_RS22285	COG4106	trans-aconitate 2-methyltransferase activity
KD35_RS22290	COG1073	alpha beta
KD35_RS22290	COG2226	methyltransferase
KD35_RS22305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_RS22315	COG1757	Na H antiporter
KD35_RS22320	COG0737	Belongs to the 5'-nucleotidase family
KD35_RS22330	COG1522	sequence-specific DNA binding
KD35_RS22350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KD35_RS22360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KD35_RS22375	COG0300	oxidoreductase activity
KD35_RS22380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS22390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_RS22395	COG1760	l-serine dehydratase
KD35_RS22400	COG1760	l-serine dehydratase
KD35_RS22420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KD35_RS22430	COG2195	Cleaves the N-terminal amino acid of tripeptides
KD35_RS22435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS22450	COG1376	ErfK ybiS ycfS ynhG family protein
KD35_RS22455	COG4129	membrane
KD35_RS22460	COG1126	abc transporter atp-binding protein
KD35_RS22465	COG0765	amino acid transport
KD35_RS22470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_RS22490	COG0772	Belongs to the SEDS family
KD35_RS22500	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_RS22505	COG0022	dehydrogenase e1 component
KD35_RS22510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_RS22515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KD35_RS22530	COG0280	phosphate acetyltransferase
KD35_RS22540	COG3290	protein histidine kinase activity
KD35_RS22540	COG3829	transcription factor binding
KD35_RS22550	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_RS22555	COG3093	addiction module antidote protein HigA
KD35_RS22565	COG0745	RESPONSE REGULATOR receiver
KD35_RS22575	COG0750	zinc metalloprotease
KD35_RS22580	COG0497	DNA recombination
KD35_RS22590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KD35_RS22600	COG0142	geranyltranstransferase activity
KD35_RS22625	COG1302	Protein conserved in bacteria
KD35_RS22630	COG0439	Biotin carboxylase
KD35_RS22635	COG0511	ligase activity, forming carbon-carbon bonds
KD35_RS22680	COG3854	ATPases associated with a variety of cellular activities
KD35_RS22705	COG0006	proline dipeptidase activity
KD35_RS22720	COG3872	metal-dependent enzyme
KD35_RS22730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KD35_RS22750	COG0095	Lipoate-protein ligase
KD35_RS22755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS22760	COG1609	Transcriptional regulator
KD35_RS22770	COG2076	Multidrug Resistance protein
KD35_RS22775	COG2076	Multidrug Resistance protein
KD35_RS22815	COG1131	(ABC) transporter
KD35_RS22820	COG1725	Transcriptional regulator
KD35_RS22850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_RS22905	COG4970	Tfp pilus assembly protein FimT
KD35_RS22915	COG1459	type II secretion system
KD35_RS22920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KD35_RS22970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KD35_RS22975	COG1410	methionine synthase
KD35_RS22975	COG0646	methionine synthase
KD35_RS22980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KD35_RS22980	COG0646	methionine synthase
KD35_RS22990	COG0626	cystathionine gamma-synthase activity
KD35_RS22995	COG0626	cystathionine gamma-synthase activity
KD35_RS23020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS23030	COG1940	carbohydrate kinase activity
KD35_RS23035	COG4483	Protein conserved in bacteria
KD35_RS23040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KD35_RS23045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KD35_RS23050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KD35_RS23055	COG0704	Plays a role in the regulation of phosphate uptake
KD35_RS23065	COG0581	inorganic phosphate transmembrane transporter activity
KD35_RS23070	COG0573	inorganic phosphate transmembrane transporter activity
KD35_RS23075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KD35_RS23080	COG0768	penicillin binding
KD35_RS23085	COG0477	Major facilitator Superfamily
KD35_RS23090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_RS23115	COG0735	belongs to the Fur family
KD35_RS23120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KD35_RS23125	COG1121	(ABC) transporter
KD35_RS23130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS23160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KD35_RS23165	COG2384	SAM-dependent methyltransferase
KD35_RS23170	COG2010	Cytochrome c
KD35_RS23175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KD35_RS23180	COG0358	DNA primase activity
KD35_RS23200	COG0517	IMP dehydrogenase activity
KD35_RS23215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KD35_RS23220	COG0295	cytidine deaminase activity
KD35_RS23225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KD35_RS23235	COG1480	7TM receptor with intracellular HD hydrolase
KD35_RS23240	COG1702	phosphate starvation-inducible protein PhoH
KD35_RS23260	COG1610	YqeY-like protein
KD35_RS23265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KD35_RS23270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KD35_RS23275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KD35_RS23305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KD35_RS23310	COG1733	regulation of RNA biosynthetic process
KD35_RS23335	COG1466	dna polymerase III delta subunit
KD35_RS23345	COG2333	competence protein COMEC
KD35_RS23345	COG0658	competence protein
KD35_RS23350	COG2131	deaminase
KD35_RS23355	COG1555	photosystem II stabilization
KD35_RS23355	COG1596	polysaccharide export
KD35_RS23360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_RS23365	COG2226	methyltransferase
KD35_RS23370	COG0799	negative regulation of ribosome biogenesis
KD35_RS23375	COG1713	HD superfamily hydrolase involved in NAD metabolism
KD35_RS23385	COG1534	Rna-binding protein
KD35_RS23395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KD35_RS23400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KD35_RS23425	COG1595	DNA-templated transcription, initiation
KD35_RS23435	COG0778	Nitroreductase
KD35_RS23440	COG2357	RelA SpoT domain protein
KD35_RS23450	COG1785	Belongs to the alkaline phosphatase family
KD35_RS23460	COG2267	carboxylic ester hydrolase activity
KD35_RS23495	COG1404	Belongs to the peptidase S8 family
KD35_RS23500	COG3186	Phenylalanine-4-hydroxylase
KD35_RS23510	COG2514	catechol 2,3-dioxygenase activity
KD35_RS23515	COG2514	catechol 2,3-dioxygenase activity
KD35_RS23520	COG2259	Doxx family
KD35_RS23560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_RS23570	COG1012	belongs to the aldehyde dehydrogenase family
KD35_RS23570	COG1454	alcohol dehydrogenase
KD35_RS23575	COG0626	cystathionine gamma-synthase activity
KD35_RS23580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_RS23605	COG0768	penicillin binding
KD35_RS23620	COG0826	peptidase U32
KD35_RS23625	COG0826	peptidase U32
KD35_RS23630	COG4122	O-methyltransferase activity
KD35_RS23635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KD35_RS23655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_RS23665	COG0628	permease
KD35_RS23685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KD35_RS23695	COG0482	sulfurtransferase activity
KD35_RS23700	COG1104	cysteine desulfurase activity
KD35_RS23705	COG1959	2 iron, 2 sulfur cluster binding
KD35_RS23710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KD35_RS23720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KD35_RS23745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KD35_RS23755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KD35_RS23755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KD35_RS23760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KD35_RS23765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KD35_RS23765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KD35_RS23775	COG2244	polysaccharide biosynthetic process
KD35_RS23780	COG2323	membrane
KD35_RS23790	COG1862	Preprotein translocase
KD35_RS23820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KD35_RS23830	COG0697	spore germination
KD35_RS23835	COG0697	spore germination
KD35_RS23840	COG0640	Transcriptional regulator
KD35_RS23865	COG0157	Belongs to the NadC ModD family
KD35_RS23870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KD35_RS23875	COG1104	cysteine desulfurase activity
KD35_RS23880	COG1827	regulation of RNA biosynthetic process
KD35_RS23885	COG2258	MOSC domain
KD35_RS23890	COG0077	Prephenate dehydratase
KD35_RS23895	COG0577	efflux transmembrane transporter activity
KD35_RS23900	COG0577	efflux transmembrane transporter activity
KD35_RS23905	COG1136	(ABC) transporter
KD35_RS23910	COG5002	protein histidine kinase activity
KD35_RS23920	COG0745	RESPONSE REGULATOR receiver
KD35_RS23925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KD35_RS23930	COG3290	protein histidine kinase activity
KD35_RS23940	COG2868	ribosomal protein
KD35_RS23950	COG1530	ribonuclease E activity
KD35_RS23955	COG1994	Peptidase M50
KD35_RS23960	COG0739	heme binding
KD35_RS23965	COG2894	cell division
KD35_RS23985	COG1077	Cell shape determining protein MreB Mrl
KD35_RS24005	COG0285	dihydrofolate synthase activity
KD35_RS24010	COG0525	valine-tRNA ligase activity
KD35_RS24020	COG1388	LysM domain
KD35_RS24030	COG0113	porphobilinogen synthase activity
KD35_RS24035	COG1587	Uroporphyrinogen-III synthase
KD35_RS24045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KD35_RS24055	COG1846	Transcriptional regulator
KD35_RS24060	COG1764	response to oxidative stress
KD35_RS24075	COG1067	ATP-dependent peptidase activity
KD35_RS24075	COG0470	DNA polymerase III
KD35_RS24125	COG0622	Phosphoesterase
KD35_RS24140	COG5401	PFAM Sporulation and spore germination
KD35_RS24160	COG1309	transcriptional regulator
KD35_RS24175	COG2197	response regulator
KD35_RS24180	COG2233	PERMEase
KD35_RS24190	COG0402	S-adenosylhomocysteine deaminase activity
KD35_RS24195	COG0402	S-adenosylhomocysteine deaminase activity
KD35_RS24205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_RS24215	COG0444	Belongs to the ABC transporter superfamily
KD35_RS24220	COG4608	Belongs to the ABC transporter superfamily
KD35_RS24225	COG3275	phosphorelay sensor kinase activity
KD35_RS24230	COG3279	Response regulator of the LytR AlgR family
KD35_RS24245	COG1983	PspC domain protein
KD35_RS24250	COG1396	sequence-specific DNA binding
KD35_RS24255	COG0697	spore germination
KD35_RS24265	COG1959	2 iron, 2 sulfur cluster binding
KD35_RS24270	COG1668	transmembrane transport
KD35_RS24275	COG4152	abc transporter atp-binding protein
KD35_RS24280	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KD35_RS24290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KD35_RS24295	COG1876	peptidase activity
KD35_RS24300	COG0824	Thioesterase
KD35_RS24305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KD35_RS24310	COG1053	succinate dehydrogenase
KD35_RS24315	COG2009	succinate dehydrogenase
KD35_RS24320	COG1719	4-vinyl reductase, 4VR
KD35_RS24330	COG3118	belongs to the thioredoxin family
KD35_RS24335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KD35_RS24340	COG2086	electron transfer activity
KD35_RS24345	COG1024	Enoyl-CoA hydratase
KD35_RS24350	COG1309	transcriptional regulator
KD35_RS24355	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_RS24375	COG2318	DinB family
KD35_RS24405	COG1131	(ABC) transporter
KD35_RS24410	COG2205	protein histidine kinase activity
KD35_RS24415	COG0745	RESPONSE REGULATOR receiver
KD35_RS24425	COG4895	conserved protein (DUF2196)
KD35_RS24430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KD35_RS24445	COG4509	Sortase family
KD35_RS24450	COG1120	ATPase activity
KD35_RS24465	COG5386	Cell surface protein
KD35_RS24475	COG5386	Cell surface protein
KD35_RS24480	COG1114	Component of the transport system for branched-chain amino acids
KD35_RS24485	COG1187	pseudouridine synthase activity
KD35_RS24500	COG1796	DNA polymerase
KD35_RS24500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KD35_RS24505	COG1286	toxin biosynthetic process
KD35_RS24550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KD35_RS24560	COG1418	mRNA catabolic process
KD35_RS24585	COG2814	Major facilitator Superfamily
KD35_RS24590	COG1566	PFAM secretion protein HlyD family protein
KD35_RS24595	COG1309	transcriptional regulator
KD35_RS24600	COG1363	Peptidase, m42
KD35_RS24625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_RS24635	COG1484	DNA-dependent DNA replication
KD35_RS24640	COG3611	Membrane attachment protein
KD35_RS24650	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KD35_RS24655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KD35_RS24660	COG0237	dephospho-CoA kinase activity
KD35_RS24665	COG1971	Probably functions as a manganese efflux pump
KD35_RS24675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_RS24675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_RS24680	COG5002	protein histidine kinase activity
KD35_RS24685	COG0745	RESPONSE REGULATOR receiver
KD35_RS24705	COG0538	isocitrate dehydrogenase activity
KD35_RS24710	COG0372	Belongs to the citrate synthase family
KD35_RS24725	COG0628	permease
KD35_RS24730	COG3030	protein affecting phage T7 exclusion by the F plasmid
KD35_RS24755	COG1725	Transcriptional regulator
KD35_RS24760	COG0281	malic enzyme
KD35_RS24765	COG0587	DNA-directed DNA polymerase activity
KD35_RS24780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KD35_RS24800	COG4109	DRTGG domain
KD35_RS24815	COG0006	proline dipeptidase activity
KD35_RS24850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS24855	COG0662	Cupin 2, conserved barrel domain protein
KD35_RS24865	COG1476	TRANSCRIPTIONal
KD35_RS24880	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_RS24885	COG0589	response to stress
KD35_RS24925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS24945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KD35_RS24950	COG0827	DNA restriction-modification system
KD35_RS24955	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KD35_RS24960	COG3874	Sporulation protein YtfJ
KD35_RS24975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KD35_RS24985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_RS25000	COG1104	cysteine desulfurase activity
KD35_RS25010	COG0583	DNA-binding transcription factor activity
KD35_RS25015	COG0697	spore germination
KD35_RS25025	COG1956	GAF domain-containing protein
KD35_RS25030	COG0626	cystathionine gamma-synthase activity
KD35_RS25060	COG1595	DNA-templated transcription, initiation
KD35_RS25070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_RS25075	COG0454	-acetyltransferase
KD35_RS25080	COG0517	IMP dehydrogenase activity
KD35_RS25085	COG0123	including yeast histone deacetylase and acetoin utilization protein
KD35_RS25095	COG0745	RESPONSE REGULATOR receiver
KD35_RS25105	COG0666	response to abiotic stimulus
KD35_RS25140	COG1609	Transcriptional regulator
KD35_RS25150	COG4851	CamS sex pheromone cAM373 precursor
KD35_RS25155	COG3118	belongs to the thioredoxin family
KD35_RS25165	COG2309	aminopeptidase activity
KD35_RS25185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS25200	COG1674	ftsk spoiiie
KD35_RS25210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_RS25215	COG4848	Belongs to the UPF0354 family
KD35_RS25220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_RS25225	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KD35_RS25230	COG1363	Peptidase, m42
KD35_RS25240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS25255	COG0510	thiamine kinase activity
KD35_RS25260	COG1523	belongs to the glycosyl hydrolase 13 family
KD35_RS25275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_RS25280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_RS25285	COG1349	DNA-binding transcription factor activity
KD35_RS25290	COG1187	pseudouridine synthase activity
KD35_RS25295	COG2244	polysaccharide biosynthetic process
KD35_RS25300	COG2081	HI0933 family
KD35_RS25305	COG2814	Major facilitator Superfamily
KD35_RS25315	COG3832	glyoxalase III activity
KD35_RS25335	COG1329	Transcriptional regulator
KD35_RS25345	COG4975	Glucose uptake
KD35_RS25360	COG0314	molybdopterin synthase activity
KD35_RS25365	COG1763	Mo-molybdopterin cofactor biosynthetic process
KD35_RS25370	COG0303	'Molybdopterin
KD35_RS25380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_RS25405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_RS25415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KD35_RS25460	COG2814	Major facilitator Superfamily
KD35_RS25465	COG0475	glutathione-regulated potassium exporter activity
KD35_RS25470	COG0490	domain, Protein
KD35_RS25475	COG0582	viral genome integration into host DNA
KD35_RS25485	COG1136	(ABC) transporter
KD35_RS25505	COG1242	4 iron, 4 sulfur cluster binding
KD35_RS25510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KD35_RS25515	COG1131	(ABC) transporter
KD35_RS25525	COG1794	racemase activity, acting on amino acids and derivatives
KD35_RS25545	COG2267	carboxylic ester hydrolase activity
KD35_RS25550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KD35_RS25555	COG0671	phosphoesterase, PA-phosphatase related
KD35_RS25560	COG0438	transferase activity, transferring glycosyl groups
KD35_RS25570	COG0521	Mo-molybdopterin cofactor biosynthetic process
KD35_RS25625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KD35_RS25630	COG5002	protein histidine kinase activity
KD35_RS25635	COG4191	Histidine kinase
KD35_RS25640	COG2267	carboxylic ester hydrolase activity
KD35_RS25660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_RS25665	COG1116	anion transmembrane transporter activity
KD35_RS25670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_RS25695	COG0494	nUDIX hydrolase
KD35_RS25725	COG0288	reversible hydration of carbon dioxide
KD35_RS25730	COG1271	oxidase subunit
KD35_RS25735	COG1294	oxidase, subunit
KD35_RS25755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS25780	COG1842	Phage shock protein A
KD35_RS25815	COG5002	protein histidine kinase activity
KD35_RS25820	COG0745	RESPONSE REGULATOR receiver
KD35_RS25850	COG1597	lipid kinase activity
KD35_RS25885	COG0586	Pfam SNARE associated Golgi protein
KD35_RS25895	COG0577	efflux transmembrane transporter activity
KD35_RS25900	COG1136	(ABC) transporter
KD35_RS25905	COG3708	Transcriptional regulator
KD35_RS25905	COG2207	Transcriptional regulator
KD35_RS25910	COG0745	RESPONSE REGULATOR receiver
KD35_RS25920	COG0577	efflux transmembrane transporter activity
KD35_RS25930	COG0577	efflux transmembrane transporter activity
KD35_RS25935	COG0577	efflux transmembrane transporter activity
KD35_RS25940	COG1136	(ABC) transporter
KD35_RS25960	COG2188	Transcriptional regulator
KD35_RS25980	COG3964	amidohydrolase
KD35_RS26010	COG4948	Mandelate Racemase Muconate Lactonizing
KD35_RS26020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KD35_RS26025	COG0596	Alpha beta hydrolase
KD35_RS26030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KD35_RS26035	COG1169	isochorismate synthase
KD35_RS26040	COG1575	Belongs to the MenA family. Type 1 subfamily
KD35_RS26045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KD35_RS26070	COG0058	SHG alpha-glucan phosphorylase activity
KD35_RS26075	COG0297	glycogen (starch) synthase activity
KD35_RS26080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KD35_RS26190	COG0544	peptidyl-prolyl cis-trans isomerase activity
KD35_RS26225	COG1285	pathogenesis
KD35_RS26230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KD35_RS26240	COG0166	Belongs to the GPI family
KD35_RS26250	COG2155	Conserved Protein
KD35_RS26255	COG1098	S1 RNA binding domain
KD35_RS26260	COG0436	Aminotransferase
KD35_RS26265	COG1522	sequence-specific DNA binding
KD35_RS26270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KD35_RS26275	COG2267	carboxylic ester hydrolase activity
KD35_RS26285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KD35_RS26305	COG5018	Exonuclease
KD35_RS26310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_RS26330	COG2050	protein possibly involved in aromatic compounds catabolism
KD35_RS26340	COG1268	BioY protein
KD35_RS26350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KD35_RS26355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KD35_RS26370	COG3584	3D domain protein
KD35_RS26385	COG1252	NADH dehydrogenase
KD35_RS26400	COG3708	Transcriptional regulator
KD35_RS26415	COG1683	Conserved Protein
KD35_RS26435	COG0316	Belongs to the HesB IscA family
KD35_RS26450	COG1252	NADH dehydrogenase
KD35_RS26465	COG0390	transport system, permease component
KD35_RS26470	COG2824	Alkylphosphonate utilization operon protein PhnA
KD35_RS26510	COG4837	Protein of unknown function (DUF1462)
KD35_RS26515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KD35_RS26525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_RS26530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KD35_RS26545	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_RS26550	COG0647	UMP catabolic process
KD35_RS26560	COG2445	Protein of unknown function DUF86
KD35_RS26565	COG1494	fructose-1,6-bisphosphatase
KD35_RS26585	COG4470	Protein conserved in bacteria
KD35_RS26595	COG0789	Transcriptional regulator
KD35_RS26600	COG4377	Putative membrane peptidase family (DUF2324)
KD35_RS26625	COG0739	heme binding
KD35_RS26635	COG3377	Domain of unknown function (DUF1805)
KD35_RS26640	COG0737	Belongs to the 5'-nucleotidase family
KD35_RS26650	COG1695	Transcriptional regulator
KD35_RS26665	COG0719	Fe-S assembly protein
KD35_RS26670	COG0822	iron-sulfur transferase activity
KD35_RS26675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KD35_RS26680	COG0719	Fe-S assembly protein
KD35_RS26685	COG0396	ATPase activity
KD35_RS26690	COG1464	Belongs to the NlpA lipoprotein family
KD35_RS26695	COG1464	Belongs to the NlpA lipoprotein family
KD35_RS26700	COG2011	ABC-type metal ion transport system permease component
KD35_RS26705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_RS26720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_RS26725	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KD35_RS26735	COG1393	Belongs to the ArsC family
KD35_RS26785	COG0039	L-malate dehydrogenase activity
KD35_RS26805	COG1309	transcriptional regulator
KD35_RS26810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_RS26815	COG1960	acyl-CoA dehydrogenase activity
KD35_RS26825	COG0183	Belongs to the thiolase family
KD35_RS26830	COG1024	Enoyl-CoA hydratase
KD35_RS26830	COG1250	3-hydroxyacyl-CoA dehydrogenase
KD35_RS26840	COG1686	Belongs to the peptidase S11 family
KD35_RS26855	COG0011	TIGRFAM Protein of
KD35_RS26860	COG0840	transmembrane signaling receptor activity
KD35_RS26880	COG2814	Major facilitator Superfamily
KD35_RS26885	COG0531	amino acid
KD35_RS26895	COG0706	membrane insertase activity
KD35_RS26905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_RS26940	COG0586	Pfam SNARE associated Golgi protein
KD35_RS26950	COG1376	ErfK ybiS ycfS ynhG family protein
KD35_RS26955	COG0745	RESPONSE REGULATOR receiver
KD35_RS26960	COG5002	protein histidine kinase activity
KD35_RS26985	COG2151	metal-sulfur cluster biosynthetic enzyme
KD35_RS26990	COG3227	Zinc metalloprotease (Elastase)
KD35_RS26995	COG1741	Belongs to the pirin family
KD35_RS27010	COG0475	glutathione-regulated potassium exporter activity
KD35_RS27015	COG0490	domain, Protein
KD35_RS27025	COG1115	amino acid carrier protein
KD35_RS27030	COG0783	Belongs to the Dps family
KD35_RS27045	COG1611	Belongs to the LOG family
KD35_RS27060	COG2311	Membrane
KD35_RS27070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS27075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_RS27080	COG1115	amino acid carrier protein
KD35_RS27085	COG1115	amino acid carrier protein
KD35_RS27090	COG2910	NAD(P)H-binding
KD35_RS27105	COG0656	L-ascorbic acid biosynthetic process
KD35_RS27110	COG2814	Major facilitator Superfamily
KD35_RS27115	COG1733	regulation of RNA biosynthetic process
KD35_RS27125	COG1252	NADH dehydrogenase
KD35_RS27130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KD35_RS27135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KD35_RS27145	COG0840	transmembrane signaling receptor activity
KD35_RS27145	COG3290	protein histidine kinase activity
KD35_RS27155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KD35_RS27160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KD35_RS27175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_RS27225	COG0557	exoribonuclease II activity
KD35_RS27230	COG1647	Serine aminopeptidase, S33
KD35_RS27235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KD35_RS27240	COG1346	cytolysis
KD35_RS27340	COG4695	Portal protein
KD35_RS27365	COG4974	Belongs to the 'phage' integrase family
KD35_RS27375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KD35_RS27380	COG0149	triose-phosphate isomerase activity
KD35_RS27390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KD35_RS27405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KD35_RS27430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_RS27445	COG2323	membrane
KD35_RS27450	COG0740	serine-type endopeptidase activity
KD35_RS27455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_RS27465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KD35_RS27475	COG1051	belongs to the nudix hydrolase family
KD35_RS27485	COG0492	ferredoxin-NADP+ reductase activity
KD35_RS27490	COG0457	Tetratricopeptide repeat
KD35_RS27495	COG0110	maltose O-acetyltransferase activity
KD35_RS27515	COG1950	PFAM Membrane protein of
KD35_RS27525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_RS27530	COG0556	nucleotide-excision repair
KD35_RS27550	COG0789	Transcriptional regulator
KD35_RS27575	COG2855	membrane
KD35_RS27580	COG0583	DNA-binding transcription factor activity
KD35_RS27590	COG0655	NAD(P)H dehydrogenase (quinone) activity
KD35_RS27605	COG1132	(ABC) transporter
KD35_RS27610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_RS27615	COG3409	Peptidoglycan-binding domain 1 protein
KD35_RS27615	COG0793	Belongs to the peptidase S41A family
KD35_RS27620	COG2177	Part of the ABC transporter FtsEX involved in
KD35_RS27625	COG2884	Cell division ATP-binding protein ftsE
KD35_RS27640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KD35_RS27645	COG0653	protein targeting
KD35_RS27650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KD35_RS27655	COG1278	Cold shock
KD35_RS27660	COG1040	competence protein
KD35_RS27665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KD35_RS27670	COG1388	LysM domain
KD35_RS27670	COG0791	NLP P60 protein
KD35_RS27675	COG1733	regulation of RNA biosynthetic process
KD35_RS27685	COG1307	EDD domain protein, DegV family
KD35_RS27690	COG1739	Uncharacterized protein family UPF0029
KD35_RS27695	COG1316	TRANSCRIPTIONal
KD35_RS27700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KD35_RS27705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KD35_RS27710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KD35_RS27720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KD35_RS27720	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KD35_RS27735	COG3394	polysaccharide catabolic process
KD35_RS27740	COG1486	melibiose metabolic process
KD35_RS27745	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_RS27750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_RS27760	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KD35_RS27765	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KD35_RS27770	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_RS27780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_RS27785	COG1301	dicarboxylic acid transport
KD35_RS27795	COG0346	lactoylglutathione lyase activity
KD35_RS27800	COG1511	domain protein
KD35_RS27805	COG0583	DNA-binding transcription factor activity
KD35_RS27810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KD35_RS28055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KD35_RS28065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KD35_RS28565	COG2814	Major facilitator Superfamily
KD35_RS28585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_RS28940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KD35_RS29155	COG2376	Dihydroxyacetone kinase