locus-tag	class	description
KM417_RS00010	COG0592	DNA-directed DNA polymerase activity
KM417_RS00015	COG2501	S4 domain
KM417_RS00025	COG0187	DNA topoisomerase II activity
KM417_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM417_RS00065	COG0516	GMP reductase activity
KM417_RS00065	COG0517	IMP dehydrogenase activity
KM417_RS00070	COG1686	Belongs to the peptidase S11 family
KM417_RS00100	COG1428	Deoxynucleoside kinase
KM417_RS00105	COG1428	Deoxynucleoside kinase
KM417_RS00110	COG1335	isochorismatase
KM417_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM417_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM417_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM417_RS00190	COG0470	DNA polymerase III
KM417_RS00195	COG1774	PSP1 C-terminal conserved region
KM417_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM417_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM417_RS00220	COG2002	toxin-antitoxin pair type II binding
KM417_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_RS00230	COG0084	hydrolase, TatD family'
KM417_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM417_RS00250	COG4466	Protein conserved in bacteria
KM417_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM417_RS00270	COG0251	oxidation-reduction process
KM417_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM417_RS00305	COG2002	toxin-antitoxin pair type II binding
KM417_RS00310	COG2244	polysaccharide biosynthetic process
KM417_RS00315	COG3956	TIGRFAM MazG family protein
KM417_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM417_RS00340	COG1098	S1 RNA binding domain
KM417_RS00355	COG2208	phosphoserine phosphatase activity
KM417_RS00360	COG0037	tRNA processing
KM417_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM417_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM417_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM417_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM417_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM417_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM417_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM417_RS00420	COG1396	sequence-specific DNA binding
KM417_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM417_RS00455	COG3880	PFAM UvrB UvrC protein
KM417_RS00465	COG0542	response to heat
KM417_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM417_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM417_RS00500	COG1045	serine acetyltransferase
KM417_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM417_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM417_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM417_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM417_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM417_RS00565	COG2813	Specifically methylates the guanine in position
KM417_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM417_RS00580	COG1358	cellular component organization or biogenesis
KM417_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM417_RS00710	COG0201	protein transport
KM417_RS00720	COG0024	Methionine aminopeptidase
KM417_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM417_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM417_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_RS00795	COG0489	protein tyrosine kinase activity
KM417_RS00805	COG2194	sulfuric ester hydrolase activity
KM417_RS00810	COG0726	polysaccharide deacetylase
KM417_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM417_RS00895	COG4856	YbbR-like protein
KM417_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM417_RS00915	COG0596	Alpha beta hydrolase
KM417_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM417_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM417_RS00940	COG1506	peptidase
KM417_RS00940	COG4946	Tricorn protease homolog
KM417_RS00975	COG2011	ABC-type metal ion transport system permease component
KM417_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM417_RS00990	COG0604	alcohol dehydrogenase
KM417_RS01000	COG0277	FAD linked oxidase domain protein
KM417_RS01005	COG2271	Major facilitator Superfamily
KM417_RS01015	COG2814	Major facilitator Superfamily
KM417_RS01030	COG0601	transmembrane transport
KM417_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM417_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM417_RS01050	COG4166	transmembrane transport
KM417_RS01060	COG2207	Transcriptional regulator
KM417_RS01075	COG4166	transmembrane transport
KM417_RS01080	COG4166	transmembrane transport
KM417_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM417_RS01105	COG4149	molybdate abc transporter
KM417_RS01115	COG1910	domain protein
KM417_RS01125	COG0583	DNA-binding transcription factor activity
KM417_RS01130	COG0697	spore germination
KM417_RS01145	COG0204	Acyl-transferase
KM417_RS01155	COG1609	Transcriptional regulator
KM417_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS01175	COG0084	hydrolase, TatD family'
KM417_RS01180	COG5298	Protein conserved in bacteria
KM417_RS01205	COG0488	(ABC) transporter
KM417_RS01220	COG0747	negative chemotaxis
KM417_RS01225	COG0601	transmembrane transport
KM417_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM417_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM417_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM417_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM417_RS01290	COG2814	Major facilitator Superfamily
KM417_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM417_RS01310	COG4294	response to UV
KM417_RS01315	COG0705	Rhomboid family
KM417_RS01315	COG0457	Tetratricopeptide repeat
KM417_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM417_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM417_RS01335	COG0864	Transcriptional regulator
KM417_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM417_RS01345	COG2183	response to ionizing radiation
KM417_RS01440	COG0802	atpase or kinase
KM417_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM417_RS01450	COG0456	acetyltransferase
KM417_RS01460	COG0488	(ABC) transporter
KM417_RS01475	COG1266	CAAX protease self-immunity
KM417_RS01495	COG2252	PERMEase
KM417_RS01505	COG5002	protein histidine kinase activity
KM417_RS01535	COG2226	methyltransferase
KM417_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM417_RS01595	COG2205	protein histidine kinase activity
KM417_RS01600	COG0745	RESPONSE REGULATOR receiver
KM417_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM417_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM417_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM417_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM417_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM417_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM417_RS01680	COG0151	Belongs to the GarS family
KM417_RS01705	COG0210	DNA helicase
KM417_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM417_RS01735	COG1335	isochorismatase
KM417_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_RS01745	COG2011	ABC-type metal ion transport system permease component
KM417_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM417_RS01775	COG1846	Transcriptional regulator
KM417_RS01800	COG1597	lipid kinase activity
KM417_RS01805	COG0546	phosphoglycolate phosphatase activity
KM417_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM417_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS01825	COG2076	Multidrug Resistance protein
KM417_RS01830	COG2309	aminopeptidase activity
KM417_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM417_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM417_RS01865	COG4807	Protein conserved in bacteria
KM417_RS01890	COG1757	Na H antiporter
KM417_RS01895	COG1473	amidohydrolase
KM417_RS01910	COG0450	alkyl hydroperoxide reductase
KM417_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS01955	COG0166	Belongs to the GPI family
KM417_RS01990	COG5002	protein histidine kinase activity
KM417_RS02010	COG3541	Predicted nucleotidyltransferase
KM417_RS02015	COG2814	Major facilitator Superfamily
KM417_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
KM417_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_RS02030	COG0765	amino acid transport
KM417_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_RS02045	COG0840	transmembrane signaling receptor activity
KM417_RS02050	COG0840	transmembrane signaling receptor activity
KM417_RS02055	COG0366	Alpha amylase catalytic
KM417_RS02060	COG1263	PTS System
KM417_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS02060	COG2190	(PTS) system
KM417_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM417_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_RS02115	COG1116	anion transmembrane transporter activity
KM417_RS02120	COG0488	(ABC) transporter
KM417_RS02165	COG2270	Major facilitator Superfamily
KM417_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_RS02195	COG2310	stress, protein
KM417_RS02200	COG2310	stress, protein
KM417_RS02205	COG2310	stress, protein
KM417_RS02210	COG0861	Integral membrane protein TerC family
KM417_RS02220	COG3853	Toxic anion resistance protein (TelA)
KM417_RS02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM417_RS02245	COG1295	ribonuclease BN
KM417_RS02250	COG2217	Heavy metal translocating P-type atpase
KM417_RS02255	COG0697	spore germination
KM417_RS02275	COG0586	Pfam SNARE associated Golgi protein
KM417_RS02290	COG3871	stress protein (general stress protein 26)
KM417_RS02295	COG0387	Pfam Sodium calcium exchanger
KM417_RS02305	COG0535	radical SAM domain protein
KM417_RS02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM417_RS02335	COG0582	viral genome integration into host DNA
KM417_RS02345	COG1396	sequence-specific DNA binding
KM417_RS02360	COG1396	sequence-specific DNA binding
KM417_RS02395	COG1484	DNA-dependent DNA replication
KM417_RS02625	COG0101	tRNA pseudouridine synthase activity
KM417_RS02635	COG3829	transcription factor binding
KM417_RS02645	COG0833	amino acid
KM417_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM417_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS02680	COG1263	PTS System
KM417_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_RS02700	COG0463	Glycosyl transferase, family 2
KM417_RS02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM417_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM417_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM417_RS02745	COG1228	amidohydrolase
KM417_RS02750	COG1090	epimerase
KM417_RS02780	COG1988	membrane-bound metal-dependent
KM417_RS02785	COG1194	a g-specific adenine glycosylase
KM417_RS02810	COG1132	(ABC) transporter
KM417_RS02815	COG4129	membrane
KM417_RS02820	COG0067	glutamate synthase
KM417_RS02820	COG0070	glutamate synthase
KM417_RS02820	COG0069	glutamate synthase activity
KM417_RS02830	COG4555	ABC transporter
KM417_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM417_RS02855	COG0735	belongs to the Fur family
KM417_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM417_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM417_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM417_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM417_RS03005	COG2766	serine protein kinase
KM417_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM417_RS03040	COG2268	Band 7 protein
KM417_RS03050	COG3290	protein histidine kinase activity
KM417_RS03055	COG4565	transcriptional regulatory protein
KM417_RS03060	COG2851	Citrate transporter
KM417_RS03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM417_RS03085	COG3842	ATPase activity
KM417_RS03090	COG1175	transmembrane transport
KM417_RS03095	COG0395	ABC-type sugar transport system, permease component
KM417_RS03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM417_RS03110	COG0745	RESPONSE REGULATOR receiver
KM417_RS03115	COG5002	protein histidine kinase activity
KM417_RS03125	COG4990	cell redox homeostasis
KM417_RS03135	COG3290	protein histidine kinase activity
KM417_RS03140	COG4565	transcriptional regulatory protein
KM417_RS03145	COG3493	citrate carrier protein
KM417_RS03150	COG0281	malic enzyme
KM417_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS03175	COG5002	protein histidine kinase activity
KM417_RS03180	COG0745	RESPONSE REGULATOR receiver
KM417_RS03185	COG0456	acetyltransferase
KM417_RS03185	COG0454	-acetyltransferase
KM417_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM417_RS03195	COG3383	formate dehydrogenase (NAD+) activity
KM417_RS03215	COG0531	amino acid
KM417_RS03220	COG0640	Transcriptional regulator
KM417_RS03225	COG2217	Heavy metal translocating P-type atpase
KM417_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM417_RS03245	COG3227	Zinc metalloprotease (Elastase)
KM417_RS03265	COG2720	vancomycin resistance protein
KM417_RS03270	COG1316	TRANSCRIPTIONal
KM417_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS03280	COG0346	lactoylglutathione lyase activity
KM417_RS03290	COG1027	Aspartate ammonia-lyase
KM417_RS03295	COG1620	l-lactate permease
KM417_RS03310	COG3104	oligopeptide transport
KM417_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS03335	COG2226	methyltransferase
KM417_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
KM417_RS03355	COG4548	von Willebrand factor, type A
KM417_RS03360	COG0714	Associated with various cellular activities
KM417_RS03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_RS03385	COG0531	amino acid
KM417_RS03390	COG2188	Transcriptional regulator
KM417_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS03395	COG1263	PTS System
KM417_RS03400	COG0366	Alpha amylase catalytic
KM417_RS03415	COG0697	spore germination
KM417_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_RS03430	COG1115	amino acid carrier protein
KM417_RS03435	COG1126	abc transporter atp-binding protein
KM417_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_RS03445	COG0765	amino acid transport
KM417_RS03450	COG0765	amino acid transport
KM417_RS03455	COG0833	amino acid
KM417_RS03480	COG2378	regulation of single-species biofilm formation
KM417_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM417_RS03490	COG5002	protein histidine kinase activity
KM417_RS03505	COG0659	secondary active sulfate transmembrane transporter activity
KM417_RS03520	COG0747	negative chemotaxis
KM417_RS03530	COG0601	transmembrane transport
KM417_RS03535	COG4608	Belongs to the ABC transporter superfamily
KM417_RS03545	COG2271	Major facilitator Superfamily
KM417_RS03550	COG1846	Transcriptional regulator
KM417_RS03560	COG1609	Transcriptional regulator
KM417_RS03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM417_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM417_RS03585	COG1879	ABC-type sugar transport system periplasmic component
KM417_RS03610	COG1063	alcohol dehydrogenase
KM417_RS03625	COG3568	Endonuclease Exonuclease Phosphatase
KM417_RS03650	COG1968	undecaprenyl-diphosphatase activity
KM417_RS03655	COG0840	transmembrane signaling receptor activity
KM417_RS03660	COG3584	3D domain protein
KM417_RS03660	COG1388	LysM domain
KM417_RS03665	COG1476	TRANSCRIPTIONal
KM417_RS03680	COG3104	oligopeptide transport
KM417_RS03685	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS03700	COG1113	amino acid transport
KM417_RS03705	COG2252	PERMEase
KM417_RS03730	COG0475	glutathione-regulated potassium exporter activity
KM417_RS03730	COG0569	domain protein
KM417_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM417_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM417_RS03755	COG4990	cell redox homeostasis
KM417_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_RS03775	COG0697	spore germination
KM417_RS03780	COG0531	amino acid
KM417_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_RS03800	COG1918	ferrous iron import across plasma membrane
KM417_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_RS03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM417_RS03810	COG0573	inorganic phosphate transmembrane transporter activity
KM417_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
KM417_RS03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM417_RS03945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM417_RS03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM417_RS03970	COG1116	anion transmembrane transporter activity
KM417_RS03975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_RS03980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_RS03985	COG0352	thiamine-phosphate diphosphorylase activity
KM417_RS03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_RS03995	COG2104	thiamine diphosphate biosynthetic process
KM417_RS04005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_RS04010	COG0351	phosphomethylpyrimidine kinase
KM417_RS04050	COG2205	protein histidine kinase activity
KM417_RS04055	COG2814	Major facilitator Superfamily
KM417_RS04060	COG1846	Transcriptional regulator
KM417_RS04075	COG2252	PERMEase
KM417_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM417_RS04100	COG1621	beta-fructofuranosidase activity
KM417_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS04105	COG1263	PTS System
KM417_RS04110	COG1609	Transcriptional regulator
KM417_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_RS04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM417_RS04160	COG0778	Nitroreductase
KM417_RS04165	COG2719	SpoVR family
KM417_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM417_RS04195	COG1937	Protein conserved in bacteria
KM417_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
KM417_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
KM417_RS04225	COG2210	Belongs to the sulfur carrier protein TusA family
KM417_RS04230	COG0730	response to heat
KM417_RS04240	COG1316	TRANSCRIPTIONal
KM417_RS04245	COG0604	alcohol dehydrogenase
KM417_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM417_RS04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_RS04265	COG3711	transcriptional antiterminator
KM417_RS04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_RS04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_RS04295	COG1388	LysM domain
KM417_RS04295	COG3584	3D domain protein
KM417_RS04300	COG0577	efflux transmembrane transporter activity
KM417_RS04305	COG1136	(ABC) transporter
KM417_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
KM417_RS04330	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS04335	COG3546	catalase activity
KM417_RS04370	COG0586	Pfam SNARE associated Golgi protein
KM417_RS04405	COG0531	amino acid
KM417_RS04410	COG0475	glutathione-regulated potassium exporter activity
KM417_RS04420	COG1737	Transcriptional regulator
KM417_RS04430	COG1263	PTS System
KM417_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS04440	COG2259	Doxx family
KM417_RS04455	COG0697	spore germination
KM417_RS04460	COG1522	sequence-specific DNA binding
KM417_RS04475	COG2076	Multidrug Resistance protein
KM417_RS04480	COG1309	transcriptional regulator
KM417_RS04485	COG2814	Major facilitator Superfamily
KM417_RS04490	COG1733	regulation of RNA biosynthetic process
KM417_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_RS04505	COG4533	DNA binding
KM417_RS04510	COG2211	Major facilitator Superfamily
KM417_RS04520	COG0693	protein deglycase activity
KM417_RS04525	COG0693	protein deglycase activity
KM417_RS04525	COG0753	catalase activity
KM417_RS04535	COG0531	amino acid
KM417_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM417_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS04555	COG1132	(ABC) transporter
KM417_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_RS04570	COG0765	amino acid transport
KM417_RS04575	COG1126	abc transporter atp-binding protein
KM417_RS04590	COG0189	ligase activity
KM417_RS04620	COG0028	Belongs to the TPP enzyme family
KM417_RS04625	COG3527	Alpha-acetolactate decarboxylase
KM417_RS04640	COG0561	phosphatase activity
KM417_RS04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM417_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
KM417_RS04690	COG0653	protein targeting
KM417_RS04695	COG2244	polysaccharide biosynthetic process
KM417_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_RS04710	COG4196	transglutaminase domain protein
KM417_RS04725	COG1696	Membrane protein involved in D-alanine export
KM417_RS04740	COG1024	Enoyl-CoA hydratase
KM417_RS04760	COG1363	Peptidase, m42
KM417_RS04780	COG3938	Belongs to the proline racemase family
KM417_RS04820	COG0601	transmembrane transport
KM417_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_RS04835	COG4608	Belongs to the ABC transporter superfamily
KM417_RS04870	COG0477	Major facilitator Superfamily
KM417_RS04875	COG3290	protein histidine kinase activity
KM417_RS04880	COG4565	transcriptional regulatory protein
KM417_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
KM417_RS04915	COG4978	Transcriptional regulator
KM417_RS04915	COG0789	Transcriptional regulator
KM417_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
KM417_RS04970	COG0477	Major facilitator Superfamily
KM417_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_RS05015	COG3320	Male sterility
KM417_RS05020	COG1309	transcriptional regulator
KM417_RS05040	COG1183	phosphatidylcholine synthase activity
KM417_RS05060	COG2376	Dihydroxyacetone kinase
KM417_RS05070	COG2376	Dihydroxyacetone kinase
KM417_RS05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_RS05080	COG1959	2 iron, 2 sulfur cluster binding
KM417_RS05110	COG2770	Histidine kinase
KM417_RS05110	COG3437	response regulator, receiver
KM417_RS05160	COG3237	CsbD-like
KM417_RS05185	COG1191	sigma factor activity
KM417_RS05195	COG2208	phosphoserine phosphatase activity
KM417_RS05200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM417_RS05205	COG2205	protein histidine kinase activity
KM417_RS05205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_RS05205	COG0784	Response regulator, receiver
KM417_RS05205	COG2198	Histidine kinase
KM417_RS05260	COG0420	3'-5' exonuclease activity
KM417_RS05285	COG1309	transcriptional regulator
KM417_RS05290	COG2814	Major facilitator Superfamily
KM417_RS05295	COG0346	lactoylglutathione lyase activity
KM417_RS05305	COG0457	Tetratricopeptide repeat
KM417_RS05310	COG2267	carboxylic ester hydrolase activity
KM417_RS05330	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM417_RS05335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM417_RS05345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM417_RS05385	COG0477	Major facilitator Superfamily
KM417_RS05390	COG0477	Major facilitator Superfamily
KM417_RS05400	COG3973	AAA domain
KM417_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_RS05425	COG4980	gas vesicle protein
KM417_RS05430	COG0537	adenosine 5'-monophosphoramidase activity
KM417_RS05435	COG1131	(ABC) transporter
KM417_RS05440	COG4473	ABC transporter
KM417_RS05455	COG1309	transcriptional regulator
KM417_RS05465	COG3402	PFAM membrane-flanked domain
KM417_RS05510	COG3402	PFAM membrane-flanked domain
KM417_RS05515	COG3428	Bacterial PH domain
KM417_RS05520	COG2329	Antibiotic biosynthesis monooxygenase
KM417_RS05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_RS05530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM417_RS05535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM417_RS05540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM417_RS05575	COG1309	transcriptional regulator
KM417_RS05580	COG1511	domain protein
KM417_RS05605	COG1609	Transcriptional regulator
KM417_RS05615	COG1234	tRNA 3'-trailer cleavage
KM417_RS05620	COG0095	Lipoate-protein ligase
KM417_RS05630	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS05660	COG3209	COG3209 Rhs family protein
KM417_RS05700	COG1078	dGTPase activity
KM417_RS05710	COG1595	DNA-templated transcription, initiation
KM417_RS05715	COG2207	Transcriptional regulator
KM417_RS05715	COG3708	Transcriptional regulator
KM417_RS05730	COG2205	protein histidine kinase activity
KM417_RS05735	COG0745	RESPONSE REGULATOR receiver
KM417_RS05760	COG0501	Belongs to the peptidase M48B family
KM417_RS05765	COG0840	transmembrane signaling receptor activity
KM417_RS05770	COG0697	spore germination
KM417_RS05790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM417_RS05795	COG2224	Isocitrate lyase
KM417_RS05820	COG4903	ComK protein
KM417_RS05825	COG0398	Pfam SNARE associated Golgi protein
KM417_RS05835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM417_RS05840	COG1074	ATP-dependent DNA helicase activity
KM417_RS05885	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM417_RS05910	COG0367	asparagine synthase
KM417_RS05915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM417_RS05920	COG0753	catalase activity
KM417_RS05925	COG0004	ammonium transporteR
KM417_RS05945	COG2996	Protein conserved in bacteria
KM417_RS05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_RS05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS05980	COG0561	phosphatase activity
KM417_RS05990	COG0542	response to heat
KM417_RS06000	COG2267	carboxylic ester hydrolase activity
KM417_RS06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM417_RS06025	COG5504	Zn-dependent protease
KM417_RS06035	COG0180	Tryptophanyl-tRNA synthetase
KM417_RS06045	COG4166	transmembrane transport
KM417_RS06050	COG0601	transmembrane transport
KM417_RS06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_RS06060	COG0444	Belongs to the ABC transporter superfamily
KM417_RS06065	COG4608	Belongs to the ABC transporter superfamily
KM417_RS06070	COG0534	Mate efflux family protein
KM417_RS06075	COG4166	transmembrane transport
KM417_RS06090	COG0861	Integral membrane protein TerC family
KM417_RS06095	COG4862	establishment of competence for transformation
KM417_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_RS06110	COG1164	Oligoendopeptidase f
KM417_RS06120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM417_RS06125	COG2346	COG2346, Truncated hemoglobins
KM417_RS06130	COG4116	CYTH
KM417_RS06140	COG2357	RelA SpoT domain protein
KM417_RS06150	COG0564	pseudouridine synthase activity
KM417_RS06170	COG0463	Glycosyl transferase, family 2
KM417_RS06170	COG1216	Glycosyl transferase, family 2
KM417_RS06190	COG0457	Tetratricopeptide repeat
KM417_RS06190	COG0463	Glycosyl transferase, family 2
KM417_RS06210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM417_RS06225	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM417_RS06270	COG2153	protein acetylation
KM417_RS06280	COG2382	esterase
KM417_RS06295	COG5492	domain, Protein
KM417_RS06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_RS06310	COG0512	Glutamine amidotransferase of anthranilate synthase
KM417_RS06310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM417_RS06345	COG1620	l-lactate permease
KM417_RS06350	COG5634	Uncharacterized conserved protein (DUF2278)
KM417_RS06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_RS06415	COG1476	TRANSCRIPTIONal
KM417_RS06475	COG2226	methyltransferase
KM417_RS06485	COG1686	Belongs to the peptidase S11 family
KM417_RS06490	COG0681	Belongs to the peptidase S26 family
KM417_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS06530	COG3842	ATPase activity
KM417_RS06535	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM417_RS06540	COG1177	transmembrane transport
KM417_RS06545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM417_RS06555	COG2409	Drug exporters of the RND superfamily
KM417_RS06565	COG0564	pseudouridine synthase activity
KM417_RS06575	COG2340	Cysteine-rich secretory protein family
KM417_RS06580	COG0247	lactate metabolic process
KM417_RS06585	COG0277	FAD linked oxidase domain protein
KM417_RS06590	COG3835	regulator
KM417_RS06600	COG0745	RESPONSE REGULATOR receiver
KM417_RS06605	COG5002	protein histidine kinase activity
KM417_RS06610	COG2186	Transcriptional regulator
KM417_RS06630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM417_RS06640	COG2116	formate transmembrane transporter activity
KM417_RS06645	COG0861	Integral membrane protein TerC family
KM417_RS06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_RS06660	COG2030	dehydratase
KM417_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS06685	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM417_RS06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_RS06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_RS06710	COG1840	ABC-type Fe3 transport system, periplasmic component
KM417_RS06740	COG1349	DNA-binding transcription factor activity
KM417_RS06760	COG2861	carbohydrate metabolic process
KM417_RS06770	COG3852	Histidine kinase
KM417_RS06775	COG1846	Transcriptional regulator
KM417_RS06785	COG2318	DinB family
KM417_RS06795	COG5002	protein histidine kinase activity
KM417_RS06805	COG0720	synthase
KM417_RS06820	COG4873	Protein conserved in bacteria
KM417_RS06850	COG1780	Probably involved in ribonucleotide reductase function
KM417_RS06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM417_RS06875	COG1725	Transcriptional regulator
KM417_RS06880	COG1131	(ABC) transporter
KM417_RS06890	COG1131	(ABC) transporter
KM417_RS06895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_RS06910	COG1522	sequence-specific DNA binding
KM417_RS06920	COG1335	isochorismatase
KM417_RS06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_RS06935	COG2070	2-Nitropropane dioxygenase
KM417_RS06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM417_RS06950	COG1696	Membrane protein involved in D-alanine export
KM417_RS06975	COG0716	FMN binding
KM417_RS06990	COG3173	Aminoglycoside phosphotransferase
KM417_RS07010	COG0534	Mate efflux family protein
KM417_RS07015	COG1968	undecaprenyl-diphosphatase activity
KM417_RS07030	COG1846	Transcriptional regulator
KM417_RS07040	COG1301	dicarboxylic acid transport
KM417_RS07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_RS07050	COG4709	membrane
KM417_RS07055	COG3874	Sporulation protein YtfJ
KM417_RS07075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_RS07080	COG0028	Belongs to the TPP enzyme family
KM417_RS07085	COG0440	acetolactate synthase activity
KM417_RS07090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM417_RS07100	COG0473	3-isopropylmalate dehydrogenase activity
KM417_RS07125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM417_RS07160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM417_RS07175	COG1183	phosphatidylcholine synthase activity
KM417_RS07180	COG1368	sulfuric ester hydrolase activity
KM417_RS07190	COG0019	diaminopimelate decarboxylase activity
KM417_RS07210	COG0529	Catalyzes the synthesis of activated sulfate
KM417_RS07215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM417_RS07235	COG1648	precorrin-2 dehydrogenase activity
KM417_RS07240	COG0733	neurotransmitter:sodium symporter activity
KM417_RS07260	COG1757	Na H antiporter
KM417_RS07275	COG4758	membrane
KM417_RS07280	COG4585	Histidine kinase
KM417_RS07285	COG2197	response regulator
KM417_RS07295	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS07305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM417_RS07330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM417_RS07330	COG1017	nitric oxide dioxygenase activity
KM417_RS07345	COG0730	response to heat
KM417_RS07350	COG0306	phosphate transporter
KM417_RS07355	COG1392	Phosphate transport regulator
KM417_RS07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_RS07375	COG3852	Histidine kinase
KM417_RS07380	COG1801	Protein of unknown function DUF72
KM417_RS07390	COG0582	viral genome integration into host DNA
KM417_RS07395	COG5002	protein histidine kinase activity
KM417_RS07415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM417_RS07415	COG0392	lysyltransferase activity
KM417_RS07430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_RS07435	COG1686	Belongs to the peptidase S11 family
KM417_RS07440	COG2715	membrane protein required for spore maturation
KM417_RS07445	COG0700	Nucleoside recognition
KM417_RS07450	COG1187	pseudouridine synthase activity
KM417_RS07460	COG1333	cytochrome c biogenesis protein
KM417_RS07465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM417_RS07470	COG0745	RESPONSE REGULATOR receiver
KM417_RS07475	COG5002	protein histidine kinase activity
KM417_RS07480	COG2096	Adenosyltransferase
KM417_RS07495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM417_RS07500	COG1141	Ferredoxin
KM417_RS07505	COG4955	Helix-turn-helix domain
KM417_RS07510	COG0514	ATP-dependent DNA helicase (RecQ)
KM417_RS07515	COG1266	CAAX protease self-immunity
KM417_RS07535	COG4862	establishment of competence for transformation
KM417_RS07540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM417_RS07560	COG0492	ferredoxin-NADP+ reductase activity
KM417_RS07565	COG0252	asparaginase activity
KM417_RS07635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_RS07650	COG0142	geranyltranstransferase activity
KM417_RS07660	COG0142	geranyltranstransferase activity
KM417_RS07680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM417_RS07685	COG0457	Tetratricopeptide repeat
KM417_RS07705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM417_RS07715	COG4347	Protein of unknown function (DUF1405)
KM417_RS07730	COG2738	Putative neutral zinc metallopeptidase
KM417_RS07740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS07745	COG1694	Mazg nucleotide pyrophosphohydrolase
KM417_RS07760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_RS07765	COG0438	transferase activity, transferring glycosyl groups
KM417_RS07800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM417_RS07800	COG1199	ATP-dependent helicase activity
KM417_RS07820	COG3935	DnaD domain protein
KM417_RS07825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM417_RS07835	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM417_RS07835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_RS07895	COG0116	Belongs to the methyltransferase superfamily
KM417_RS07905	COG1199	ATP-dependent helicase activity
KM417_RS07910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM417_RS07920	COG3173	Aminoglycoside phosphotransferase
KM417_RS07925	COG0024	Methionine aminopeptidase
KM417_RS07935	COG2233	PERMEase
KM417_RS07940	COG2311	Membrane
KM417_RS07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_RS07955	COG0456	acetyltransferase
KM417_RS08005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_RS08030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM417_RS08045	COG1215	transferase activity, transferring glycosyl groups
KM417_RS08050	COG0438	transferase activity, transferring glycosyl groups
KM417_RS08065	COG0454	-acetyltransferase
KM417_RS08085	COG0328	RNA-DNA hybrid ribonuclease activity
KM417_RS08125	COG1280	lysine exporter protein (LysE YggA)
KM417_RS08140	COG3162	membrane
KM417_RS08145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_RS08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_RS08160	COG0475	glutathione-regulated potassium exporter activity
KM417_RS08165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_RS08170	COG0789	Transcriptional regulator
KM417_RS08170	COG4978	Transcriptional regulator
KM417_RS08180	COG2323	membrane
KM417_RS08185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM417_RS08240	COG1923	regulation of RNA biosynthetic process
KM417_RS08250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM417_RS08255	COG1360	Flagellar Motor Protein
KM417_RS08260	COG2201	protein-glutamate methylesterase activity
KM417_RS08270	COG1776	CheC inhibitor of MCP methylation
KM417_RS08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_RS08285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM417_RS08305	COG1256	bacterial-type flagellum assembly
KM417_RS08330	COG1815	bacterial-type flagellum-dependent cell motility
KM417_RS08335	COG1558	bacterial-type flagellum-dependent cell motility
KM417_RS08350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_RS08360	COG1157	protein secretion by the type III secretion system
KM417_RS08395	COG0835	chemotaxis
KM417_RS08395	COG0784	Response regulator, receiver
KM417_RS08405	COG0463	Glycosyl transferase, family 2
KM417_RS08430	COG0463	Glycosyl transferase, family 2
KM417_RS08430	COG0457	Tetratricopeptide repeat
KM417_RS08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM417_RS08450	COG0741	lytic transglycosylase activity
KM417_RS08465	COG1776	CheC inhibitor of MCP methylation
KM417_RS08465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_RS08475	COG1338	Plays a role in the flagellum-specific transport system
KM417_RS08480	COG1987	bacterial-type flagellum assembly
KM417_RS08490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM417_RS08495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM417_RS08500	COG1419	protein localization to endoplasmic reticulum
KM417_RS08505	COG4786	Flagellar basal body rod
KM417_RS08510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_RS08535	COG1309	transcriptional regulator
KM417_RS08555	COG2329	Antibiotic biosynthesis monooxygenase
KM417_RS08580	COG0583	DNA-binding transcription factor activity
KM417_RS08590	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM417_RS08600	COG1234	tRNA 3'-trailer cleavage
KM417_RS08625	COG1686	Belongs to the peptidase S11 family
KM417_RS08635	COG0406	alpha-ribazole phosphatase activity
KM417_RS08665	COG0367	asparagine synthase
KM417_RS08695	COG1802	Transcriptional regulator
KM417_RS08700	COG0697	spore germination
KM417_RS08705	COG0523	cobalamin synthesis protein
KM417_RS08710	COG0701	Predicted permease
KM417_RS08720	COG1216	Glycosyl transferase, family 2
KM417_RS08720	COG0438	transferase activity, transferring glycosyl groups
KM417_RS08725	COG1757	Na H antiporter
KM417_RS08730	COG0114	fumarate hydratase activity
KM417_RS08755	COG3340	Belongs to the peptidase S51 family
KM417_RS08775	COG0785	Cytochrome C biogenesis protein
KM417_RS08805	COG2733	membrane
KM417_RS08840	COG1131	(ABC) transporter
KM417_RS08855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_RS08860	COG0528	UMP kinase activity
KM417_RS08870	COG1027	Aspartate ammonia-lyase
KM417_RS08875	COG0281	malic enzyme
KM417_RS08880	COG4191	Histidine kinase
KM417_RS08885	COG0784	Response regulator, receiver
KM417_RS08890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_RS08950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_RS08960	COG2814	Major facilitator Superfamily
KM417_RS08975	COG1966	Carbon starvation protein
KM417_RS08990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM417_RS09010	COG2223	nitrite transmembrane transporter activity
KM417_RS09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_RS09030	COG2244	polysaccharide biosynthetic process
KM417_RS09035	COG0733	neurotransmitter:sodium symporter activity
KM417_RS09045	COG5566	PFAM Mor transcription activator
KM417_RS09050	COG2323	membrane
KM417_RS09070	COG2084	Dehydrogenase
KM417_RS09085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_RS09095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_RS09100	COG0028	Belongs to the TPP enzyme family
KM417_RS09105	COG0440	acetolactate synthase activity
KM417_RS09110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM417_RS09120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM417_RS09145	COG2814	Major facilitator Superfamily
KM417_RS09150	COG3384	dioxygenase
KM417_RS09160	COG3279	Response regulator of the LytR AlgR family
KM417_RS09165	COG0427	acetyl-CoA hydrolase
KM417_RS09185	COG1073	alpha beta
KM417_RS09215	COG0535	radical SAM domain protein
KM417_RS09220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS09240	COG1914	H( )-stimulated, divalent metal cation uptake system
KM417_RS09255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM417_RS09285	COG2390	Transcriptional regulator
KM417_RS09295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS09300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM417_RS09315	COG4224	UPF0291 protein
KM417_RS09335	COG0006	proline dipeptidase activity
KM417_RS09340	COG2132	Multicopper oxidase
KM417_RS09355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM417_RS09370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_RS09385	COG1276	copper resistance
KM417_RS09385	COG2372	response to copper ion
KM417_RS09390	COG4549	nuclear export factor GLE1
KM417_RS09400	COG0697	spore germination
KM417_RS09405	COG0583	DNA-binding transcription factor activity
KM417_RS09410	COG1959	2 iron, 2 sulfur cluster binding
KM417_RS09415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM417_RS09420	COG0778	Nitroreductase
KM417_RS09430	COG0628	permease
KM417_RS09440	COG1231	oxidoreductase activity
KM417_RS09445	COG0523	cobalamin synthesis protein
KM417_RS09460	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS09465	COG2030	dehydratase
KM417_RS09470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS09480	COG0411	ABC transporter
KM417_RS09500	COG0583	DNA-binding transcription factor activity
KM417_RS09520	COG1846	Transcriptional regulator
KM417_RS09530	COG1271	oxidase subunit
KM417_RS09535	COG1294	oxidase, subunit
KM417_RS09540	COG4988	ABC transporter
KM417_RS09545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM417_RS09565	COG1686	Belongs to the peptidase S11 family
KM417_RS09580	COG1388	LysM domain
KM417_RS09580	COG0791	NLP P60 protein
KM417_RS09595	COG0745	RESPONSE REGULATOR receiver
KM417_RS09600	COG5002	protein histidine kinase activity
KM417_RS09610	COG0300	oxidoreductase activity
KM417_RS09645	COG0460	homoserine dehydrogenase
KM417_RS09670	COG1316	TRANSCRIPTIONal
KM417_RS09680	COG0745	RESPONSE REGULATOR receiver
KM417_RS09685	COG5002	protein histidine kinase activity
KM417_RS09700	COG1285	pathogenesis
KM417_RS09705	COG1247	-acetyltransferase
KM417_RS09725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_RS09735	COG1082	Xylose isomerase domain protein TIM barrel
KM417_RS09750	COG1279	arginine transmembrane transporter activity
KM417_RS09760	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM417_RS09800	COG2002	toxin-antitoxin pair type II binding
KM417_RS09805	COG1404	Belongs to the peptidase S8 family
KM417_RS09810	COG0640	Transcriptional regulator
KM417_RS09815	COG0667	Aldo Keto reductase
KM417_RS09820	COG2814	Major facilitator Superfamily
KM417_RS09845	COG0840	transmembrane signaling receptor activity
KM417_RS09860	COG3949	Membrane
KM417_RS09865	COG0783	Belongs to the Dps family
KM417_RS09880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_RS09890	COG1231	oxidoreductase activity
KM417_RS09900	COG4989	oxidoreductase activity
KM417_RS09905	COG0523	cobalamin synthesis protein
KM417_RS09910	COG0456	acetyltransferase
KM417_RS09970	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM417_RS09970	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM417_RS09980	COG0702	epimerase
KM417_RS09990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM417_RS10000	COG4166	transmembrane transport
KM417_RS10015	COG0406	alpha-ribazole phosphatase activity
KM417_RS10025	COG5337	Spore coat protein CotH
KM417_RS10030	COG1051	belongs to the nudix hydrolase family
KM417_RS10035	COG0586	Pfam SNARE associated Golgi protein
KM417_RS10040	COG2244	polysaccharide biosynthetic process
KM417_RS10050	COG0701	Predicted permease
KM417_RS10055	COG3689	TIGRFAM TIGR03943 family protein
KM417_RS10060	COG1607	acyl-coa hydrolase
KM417_RS10070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_RS10085	COG0702	epimerase
KM417_RS10090	COG2839	Protein conserved in bacteria
KM417_RS10095	COG1253	flavin adenine dinucleotide binding
KM417_RS10110	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_RS10135	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_RS10145	COG1876	peptidase activity
KM417_RS10155	COG0154	amidase activity
KM417_RS10160	COG2211	Major facilitator Superfamily
KM417_RS10180	COG0561	phosphatase activity
KM417_RS10190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM417_RS10195	COG4106	trans-aconitate 2-methyltransferase activity
KM417_RS10210	COG1819	glycosyl
KM417_RS10215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS10220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS10255	COG0456	acetyltransferase
KM417_RS10310	COG3874	Sporulation protein YtfJ
KM417_RS10335	COG2226	methyltransferase
KM417_RS10360	COG0346	lactoylglutathione lyase activity
KM417_RS10370	COG0604	alcohol dehydrogenase
KM417_RS10375	COG1595	DNA-templated transcription, initiation
KM417_RS10400	COG0386	Belongs to the glutathione peroxidase family
KM417_RS10405	COG1305	Transglutaminase-like
KM417_RS10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM417_RS10415	COG0714	Associated with various cellular activities
KM417_RS10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM417_RS10435	COG1140	nitrate reductase beta subunit
KM417_RS10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM417_RS10445	COG2181	nitrate reductase activity
KM417_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM417_RS10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM417_RS10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_RS10480	COG0303	'Molybdopterin
KM417_RS10485	COG0314	molybdopterin synthase activity
KM417_RS10495	COG2223	nitrite transmembrane transporter activity
KM417_RS10510	COG1648	precorrin-2 dehydrogenase activity
KM417_RS10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM417_RS10520	COG1587	Uroporphyrinogen-III synthase
KM417_RS10525	COG2146	nitrite reductase [NAD(P)H] activity
KM417_RS10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM417_RS10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM417_RS10570	COG2359	stage V sporulation protein S
KM417_RS10595	COG1418	mRNA catabolic process
KM417_RS10600	COG0488	(ABC) transporter
KM417_RS10615	COG0629	single-stranded DNA binding
KM417_RS10630	COG1413	lyase activity
KM417_RS10645	COG2521	methyltransferase
KM417_RS10645	COG2136	Putative SAM-dependent methyltransferase
KM417_RS10650	COG0018	arginyl-trna synthetase
KM417_RS10675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM417_RS10695	COG0017	Asparaginyl-tRNA synthetase
KM417_RS10715	COG1674	ftsk spoiiie
KM417_RS10785	COG1929	Belongs to the glycerate kinase type-1 family
KM417_RS10790	COG0471	metal ion transport
KM417_RS10795	COG0745	RESPONSE REGULATOR receiver
KM417_RS10800	COG5002	protein histidine kinase activity
KM417_RS10800	COG3850	Histidine kinase
KM417_RS10815	COG0733	neurotransmitter:sodium symporter activity
KM417_RS10840	COG2610	gluconate transmembrane transporter activity
KM417_RS10845	COG1454	alcohol dehydrogenase
KM417_RS10850	COG1794	racemase activity, acting on amino acids and derivatives
KM417_RS10860	COG0456	acetyltransferase
KM417_RS10875	COG1131	(ABC) transporter
KM417_RS10890	COG0546	phosphoglycolate phosphatase activity
KM417_RS10910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_RS10925	COG0768	penicillin binding
KM417_RS10930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_RS10935	COG0204	Acyl-transferase
KM417_RS10940	COG1272	protein, Hemolysin III
KM417_RS10950	COG0805	protein transport
KM417_RS10960	COG1307	EDD domain protein, DegV family
KM417_RS10965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM417_RS10970	COG1999	signal sequence binding
KM417_RS10975	COG0071	Belongs to the small heat shock protein (HSP20) family
KM417_RS10980	COG0367	asparagine synthase
KM417_RS10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_RS11035	COG0668	transmembrane transport
KM417_RS11040	COG2203	Gaf domain
KM417_RS11040	COG4585	Histidine kinase
KM417_RS11045	COG2197	response regulator
KM417_RS11055	COG1064	alcohol dehydrogenase
KM417_RS11110	COG0517	IMP dehydrogenase activity
KM417_RS11110	COG1125	glycine betaine transport
KM417_RS11115	COG1174	glycine betaine transport
KM417_RS11150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_RS11155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM417_RS11160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM417_RS11165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM417_RS11170	COG0456	acetyltransferase
KM417_RS11175	COG3829	transcription factor binding
KM417_RS11180	COG1509	lysine 2,3-aminomutase activity
KM417_RS11220	COG4326	sporulation control protein
KM417_RS11225	COG0671	phosphoesterase, PA-phosphatase related
KM417_RS11230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM417_RS11235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_RS11265	COG1787	Restriction endonuclease
KM417_RS11265	COG1715	Restriction endonuclease
KM417_RS11355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_RS11395	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM417_RS11395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_RS11405	COG2814	Major facilitator Superfamily
KM417_RS11410	COG4841	protein insertion into membrane
KM417_RS11415	COG0372	Belongs to the citrate synthase family
KM417_RS11420	COG2079	MmgE PrpD family protein
KM417_RS11425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM417_RS11430	COG1960	acyl-CoA dehydrogenase activity
KM417_RS11435	COG2084	Dehydrogenase
KM417_RS11445	COG1280	lysine exporter protein (LysE YggA)
KM417_RS11450	COG1024	Enoyl-CoA hydratase
KM417_RS11465	COG0420	3'-5' exonuclease activity
KM417_RS11470	COG0419	ATPase involved in DNA repair
KM417_RS11490	COG2223	nitrite transmembrane transporter activity
KM417_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS11500	COG1169	isochorismate synthase
KM417_RS11505	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM417_RS11510	COG1535	isochorismatase
KM417_RS11510	COG3433	isochorismatase activity
KM417_RS11515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM417_RS11520	COG3251	PFAM MbtH domain protein
KM417_RS11525	COG2814	Major facilitator Superfamily
KM417_RS11540	COG0776	regulation of translation
KM417_RS11550	COG2318	DinB family
KM417_RS11560	COG1115	amino acid carrier protein
KM417_RS11575	COG2329	Antibiotic biosynthesis monooxygenase
KM417_RS11580	COG1187	pseudouridine synthase activity
KM417_RS11585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_RS11600	COG0596	Alpha beta hydrolase
KM417_RS11605	COG2814	Major facilitator Superfamily
KM417_RS11625	COG2226	methyltransferase
KM417_RS11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS11705	COG1247	-acetyltransferase
KM417_RS11735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM417_RS11745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS11755	COG1278	Cold shock
KM417_RS11770	COG0010	Belongs to the arginase family
KM417_RS11775	COG0561	phosphatase activity
KM417_RS11820	COG0583	DNA-binding transcription factor activity
KM417_RS11825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM417_RS11840	COG0583	DNA-binding transcription factor activity
KM417_RS11845	COG2258	MOSC domain
KM417_RS11860	COG1132	(ABC) transporter
KM417_RS11865	COG1132	(ABC) transporter
KM417_RS11885	COG1396	sequence-specific DNA binding
KM417_RS11910	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM417_RS11915	COG1595	DNA-templated transcription, initiation
KM417_RS11940	COG1649	PFAM Uncharacterised BCR, COG1649
KM417_RS11965	COG2971	BadF BadG BcrA BcrD
KM417_RS11970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_RS11975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM417_RS11995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS12025	COG1309	transcriptional regulator
KM417_RS12040	COG0577	efflux transmembrane transporter activity
KM417_RS12040	COG1136	(ABC) transporter
KM417_RS12045	COG0500	methyltransferase
KM417_RS12045	COG3615	Tellurite resistance protein tehB
KM417_RS12055	COG2226	methyltransferase
KM417_RS12060	COG3961	Belongs to the TPP enzyme family
KM417_RS12065	COG1846	Transcriptional regulator
KM417_RS12105	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM417_RS12120	COG1595	DNA-templated transcription, initiation
KM417_RS12130	COG0768	penicillin binding
KM417_RS12140	COG2367	Beta-lactamase
KM417_RS12145	COG0671	phosphoesterase, PA-phosphatase related
KM417_RS12150	COG1609	Transcriptional regulator
KM417_RS12155	COG2814	Major facilitator Superfamily
KM417_RS12160	COG0673	inositol 2-dehydrogenase activity
KM417_RS12170	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS12185	COG0191	fructose-bisphosphate aldolase activity
KM417_RS12190	COG3718	enzyme involved in inositol metabolism
KM417_RS12215	COG0457	Tetratricopeptide repeat
KM417_RS12220	COG1476	TRANSCRIPTIONal
KM417_RS12235	COG1876	peptidase activity
KM417_RS12255	COG1309	transcriptional regulator
KM417_RS12260	COG0488	(ABC) transporter
KM417_RS12275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS12290	COG1252	NADH dehydrogenase
KM417_RS12295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_RS12310	COG1131	(ABC) transporter
KM417_RS12320	COG1309	transcriptional regulator
KM417_RS12335	COG1960	acyl-CoA dehydrogenase activity
KM417_RS12340	COG0439	Biotin carboxylase
KM417_RS12345	COG0511	ligase activity, forming carbon-carbon bonds
KM417_RS12350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM417_RS12355	COG1024	Enoyl-CoA hydratase
KM417_RS12360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM417_RS12365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_RS12375	COG1247	-acetyltransferase
KM417_RS12380	COG0572	uridine kinase
KM417_RS12390	COG2318	DinB family
KM417_RS12395	COG1686	Belongs to the peptidase S11 family
KM417_RS12420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM417_RS12460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_RS12460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_RS12485	COG2814	Major facilitator Superfamily
KM417_RS12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_RS12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS12540	COG1063	alcohol dehydrogenase
KM417_RS12555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM417_RS12560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM417_RS12575	COG3773	Cell wall hydrolase
KM417_RS12585	COG0745	RESPONSE REGULATOR receiver
KM417_RS12600	COG0488	(ABC) transporter
KM417_RS12615	COG1136	(ABC) transporter
KM417_RS12640	COG0460	homoserine dehydrogenase
KM417_RS12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS12655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM417_RS12720	COG2124	cytochrome p450
KM417_RS12755	COG0561	phosphatase activity
KM417_RS12765	COG0768	penicillin binding
KM417_RS12770	COG1819	glycosyl
KM417_RS12775	COG1794	racemase activity, acting on amino acids and derivatives
KM417_RS12785	COG1122	ATPase activity
KM417_RS12800	COG2205	protein histidine kinase activity
KM417_RS12810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_RS12815	COG0604	alcohol dehydrogenase
KM417_RS12820	COG0768	penicillin binding
KM417_RS12830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_RS12865	COG0693	protein deglycase activity
KM417_RS12895	COG2814	Major facilitator Superfamily
KM417_RS12910	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_RS12930	COG0697	spore germination
KM417_RS12960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_RS12970	COG2223	nitrite transmembrane transporter activity
KM417_RS12985	COG2816	NAD+ diphosphatase activity
KM417_RS12990	COG0592	DNA-directed DNA polymerase activity
KM417_RS12995	COG1051	belongs to the nudix hydrolase family
KM417_RS13030	COG3878	Protein conserved in bacteria
KM417_RS13080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM417_RS13095	COG0322	excinuclease ABC activity
KM417_RS13135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_RS13160	COG1011	Hydrolase
KM417_RS13180	COG0076	glutamate decarboxylase activity
KM417_RS13195	COG1523	belongs to the glycosyl hydrolase 13 family
KM417_RS13200	COG3227	Zinc metalloprotease (Elastase)
KM417_RS13220	COG0201	protein transport
KM417_RS13230	COG0697	spore germination
KM417_RS13235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS13265	COG4129	membrane
KM417_RS13270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS13285	COG2959	enzyme of heme biosynthesis
KM417_RS13305	COG3483	tryptophan 2,3-dioxygenase activity
KM417_RS13310	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM417_RS13315	COG3844	kynureninase activity
KM417_RS13320	COG1309	transcriptional regulator
KM417_RS13350	COG3284	Transcriptional regulator
KM417_RS13370	COG1349	DNA-binding transcription factor activity
KM417_RS13390	COG1959	2 iron, 2 sulfur cluster binding
KM417_RS13405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM417_RS13410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_RS13415	COG0022	dehydrogenase e1 component
KM417_RS13420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS13435	COG0456	acetyltransferase
KM417_RS13435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_RS13465	COG4176	ABC-type proline glycine betaine transport system permease component
KM417_RS13470	COG0517	IMP dehydrogenase activity
KM417_RS13470	COG4175	Glycine betaine
KM417_RS13495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM417_RS13500	COG2153	protein acetylation
KM417_RS13505	COG3397	chitin binding
KM417_RS13520	COG2205	protein histidine kinase activity
KM417_RS13545	COG2333	competence protein COMEC
KM417_RS13545	COG0658	competence protein
KM417_RS13595	COG3973	AAA domain
KM417_RS13610	COG2105	PFAM AIG2 family protein
KM417_RS13615	COG0514	ATP-dependent DNA helicase (RecQ)
KM417_RS13635	COG4637	Psort location Cytoplasmic, score
KM417_RS13660	COG3397	chitin binding
KM417_RS13675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM417_RS13680	COG1115	amino acid carrier protein
KM417_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS13690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM417_RS13700	COG3938	Belongs to the proline racemase family
KM417_RS13705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_RS13745	COG0586	Pfam SNARE associated Golgi protein
KM417_RS13760	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM417_RS13765	COG0519	Catalyzes the synthesis of GMP from XMP
KM417_RS13770	COG4166	transmembrane transport
KM417_RS13780	COG4948	Mandelate Racemase Muconate Lactonizing
KM417_RS13825	COG2936	dipeptidyl-peptidase activity
KM417_RS13830	COG5002	protein histidine kinase activity
KM417_RS13880	COG1307	EDD domain protein, DegV family
KM417_RS13900	COG2814	Major facilitator Superfamily
KM417_RS13910	COG1664	Polymer-forming cytoskeletal
KM417_RS13915	COG0789	Transcriptional regulator
KM417_RS13920	COG4533	DNA binding
KM417_RS13925	COG2814	Major facilitator Superfamily
KM417_RS13925	COG0477	Major facilitator Superfamily
KM417_RS13945	COG2261	transglycosylase associated protein
KM417_RS13960	COG2226	methyltransferase
KM417_RS13995	COG0436	Aminotransferase
KM417_RS14000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM417_RS14005	COG5146	pantothenate kinase activity
KM417_RS14025	COG1131	(ABC) transporter
KM417_RS14070	COG0628	permease
KM417_RS14085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_RS14090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_RS14095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_RS14100	COG1116	anion transmembrane transporter activity
KM417_RS14120	COG2816	NAD+ diphosphatase activity
KM417_RS14140	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM417_RS14165	COG0697	spore germination
KM417_RS14170	COG2318	DinB family
KM417_RS14190	COG4912	Dna alkylation repair
KM417_RS14210	COG0861	Integral membrane protein TerC family
KM417_RS14215	COG1368	sulfuric ester hydrolase activity
KM417_RS14220	COG0488	(ABC) transporter
KM417_RS14235	COG1309	transcriptional regulator
KM417_RS14250	COG0287	Prephenate dehydrogenase
KM417_RS14255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM417_RS14260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM417_RS14265	COG1605	Chorismate mutase
KM417_RS14265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM417_RS14300	COG1388	LysM domain
KM417_RS14300	COG3584	3D domain protein
KM417_RS14310	COG1595	DNA-templated transcription, initiation
KM417_RS14335	COG1879	ABC-type sugar transport system periplasmic component
KM417_RS14345	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM417_RS14355	COG2390	Transcriptional regulator
KM417_RS14390	COG2329	Antibiotic biosynthesis monooxygenase
KM417_RS14410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS14420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM417_RS14425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_RS14430	COG4187	Peptidase family M20/M25/M40
KM417_RS14435	COG1414	Transcriptional regulator
KM417_RS14440	COG0833	amino acid
KM417_RS14445	COG1690	Belongs to the RtcB family
KM417_RS14455	COG1785	Belongs to the alkaline phosphatase family
KM417_RS14465	COG3655	Transcriptional regulator
KM417_RS14480	COG4377	Putative membrane peptidase family (DUF2324)
KM417_RS14490	COG3279	Response regulator of the LytR AlgR family
KM417_RS14500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS14505	COG0346	lactoylglutathione lyase activity
KM417_RS14525	COG0714	Associated with various cellular activities
KM417_RS14550	COG0463	Glycosyl transferase, family 2
KM417_RS14570	COG0463	Glycosyl transferase, family 2
KM417_RS14580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM417_RS14585	COG0753	catalase activity
KM417_RS14595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM417_RS14620	COG0714	Associated with various cellular activities
KM417_RS14630	COG0778	Nitroreductase
KM417_RS14635	COG1846	Transcriptional regulator
KM417_RS14670	COG1725	Transcriptional regulator
KM417_RS14680	COG0577	efflux transmembrane transporter activity
KM417_RS14680	COG1136	(ABC) transporter
KM417_RS14705	COG2207	Transcriptional regulator
KM417_RS14710	COG0456	acetyltransferase
KM417_RS14730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS14750	COG0642	Histidine kinase
KM417_RS14755	COG0745	RESPONSE REGULATOR receiver
KM417_RS14760	COG0596	Alpha beta hydrolase
KM417_RS14790	COG0730	response to heat
KM417_RS14800	COG0833	amino acid
KM417_RS14810	COG4335	DNA alkylation repair
KM417_RS14850	COG0768	penicillin binding
KM417_RS14860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM417_RS14895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM417_RS14900	COG1414	Transcriptional regulator
KM417_RS14915	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_RS14920	COG0640	Transcriptional regulator
KM417_RS14930	COG1960	acyl-CoA dehydrogenase activity
KM417_RS14945	COG3314	Sporulation integral membrane protein YlbJ
KM417_RS14960	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM417_RS14975	COG0574	Belongs to the PEP-utilizing enzyme family
KM417_RS14975	COG3848	Pyruvate phosphate dikinase
KM417_RS14980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS14995	COG5577	PFAM Coat F domain
KM417_RS15000	COG3403	YqcI/YcgG family
KM417_RS15005	COG1280	lysine exporter protein (LysE YggA)
KM417_RS15040	COG1063	alcohol dehydrogenase
KM417_RS15055	COG1027	Aspartate ammonia-lyase
KM417_RS15060	COG0252	asparaginase activity
KM417_RS15065	COG1396	sequence-specific DNA binding
KM417_RS15075	COG0322	excinuclease ABC activity
KM417_RS15080	COG0531	amino acid
KM417_RS15085	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS15090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_RS15100	COG0281	malic enzyme
KM417_RS15115	COG0531	amino acid
KM417_RS15125	COG0784	Response regulator, receiver
KM417_RS15135	COG2066	Belongs to the glutaminase family
KM417_RS15140	COG1115	amino acid carrier protein
KM417_RS15170	COG0737	Belongs to the 5'-nucleotidase family
KM417_RS15175	COG0753	catalase activity
KM417_RS15180	COG2267	carboxylic ester hydrolase activity
KM417_RS15185	COG1335	isochorismatase
KM417_RS15205	COG0583	DNA-binding transcription factor activity
KM417_RS15255	COG0415	Belongs to the DNA photolyase family
KM417_RS15260	COG0288	reversible hydration of carbon dioxide
KM417_RS15270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM417_RS15275	COG5609	conserved protein (DUF2294)
KM417_RS15290	COG1575	Belongs to the MenA family. Type 1 subfamily
KM417_RS15295	COG2267	carboxylic ester hydrolase activity
KM417_RS15300	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM417_RS15305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM417_RS15310	COG1121	(ABC) transporter
KM417_RS15340	COG0798	PFAM Bile acid sodium symporter
KM417_RS15345	COG0346	lactoylglutathione lyase activity
KM417_RS15350	COG0640	Transcriptional regulator
KM417_RS15365	COG0443	Heat shock 70 kDa protein
KM417_RS15380	COG1522	sequence-specific DNA binding
KM417_RS15395	COG0346	lactoylglutathione lyase activity
KM417_RS15415	COG2169	Transcriptional regulator
KM417_RS15420	COG2169	Transcriptional regulator
KM417_RS15465	COG2814	Major facilitator Superfamily
KM417_RS15490	COG0745	RESPONSE REGULATOR receiver
KM417_RS15495	COG3850	Histidine kinase
KM417_RS15495	COG5002	protein histidine kinase activity
KM417_RS15520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM417_RS15540	COG1476	TRANSCRIPTIONal
KM417_RS15555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS15560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM417_RS15570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS15575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM417_RS15590	COG1136	(ABC) transporter
KM417_RS15595	COG0577	efflux transmembrane transporter activity
KM417_RS15610	COG3850	Histidine kinase
KM417_RS15610	COG5002	protein histidine kinase activity
KM417_RS15620	COG2364	Membrane
KM417_RS15625	COG1846	Transcriptional regulator
KM417_RS15635	COG2808	Putative FMN-binding domain
KM417_RS15640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS15645	COG2271	Major facilitator Superfamily
KM417_RS15650	COG1556	Lactate utilization protein
KM417_RS15655	COG1139	Iron-sulfur cluster binding protein
KM417_RS15665	COG0583	DNA-binding transcription factor activity
KM417_RS15675	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_RS15695	COG0738	Major facilitator superfamily
KM417_RS15700	COG0673	inositol 2-dehydrogenase activity
KM417_RS15705	COG0561	phosphatase activity
KM417_RS15715	COG1609	Transcriptional regulator
KM417_RS15720	COG0457	Tetratricopeptide repeat
KM417_RS15740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_RS15770	COG0534	Mate efflux family protein
KM417_RS15790	COG2814	Major facilitator Superfamily
KM417_RS15795	COG1309	transcriptional regulator
KM417_RS15810	COG0814	amino acid
KM417_RS15815	COG1760	l-serine dehydratase
KM417_RS15820	COG1760	l-serine dehydratase
KM417_RS15830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM417_RS15835	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM417_RS15845	COG1335	isochorismatase
KM417_RS15850	COG1522	sequence-specific DNA binding
KM417_RS15855	COG0531	amino acid
KM417_RS15875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM417_RS15895	COG1595	DNA-templated transcription, initiation
KM417_RS15910	COG0662	Cupin 2, conserved barrel domain protein
KM417_RS15915	COG2207	Transcriptional regulator
KM417_RS15915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS15965	COG0477	Major facilitator Superfamily
KM417_RS15975	COG1846	Transcriptional regulator
KM417_RS15980	COG2814	Major facilitator Superfamily
KM417_RS15990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_RS15995	COG1131	(ABC) transporter
KM417_RS16015	COG2076	Multidrug Resistance protein
KM417_RS16020	COG1309	transcriptional regulator
KM417_RS16030	COG2031	fatty acid transporter
KM417_RS16040	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_RS16070	COG1122	ATPase activity
KM417_RS16075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM417_RS16090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM417_RS16095	COG1288	antiporter activity
KM417_RS16100	COG2356	endonuclease I
KM417_RS16115	COG3620	sequence-specific DNA binding
KM417_RS16120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_RS16125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM417_RS16130	COG0124	histidyl-tRNA synthetase
KM417_RS16145	COG1733	regulation of RNA biosynthetic process
KM417_RS16150	COG0778	Nitroreductase
KM417_RS16170	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS16180	COG1131	(ABC) transporter
KM417_RS16205	COG1011	Hydrolase
KM417_RS16215	COG2365	Tyrosine phosphatase family
KM417_RS16240	COG0346	lactoylglutathione lyase activity
KM417_RS16245	COG1940	carbohydrate kinase activity
KM417_RS16250	COG0738	Major facilitator superfamily
KM417_RS16255	COG0110	maltose O-acetyltransferase activity
KM417_RS16265	COG0577	efflux transmembrane transporter activity
KM417_RS16265	COG1136	(ABC) transporter
KM417_RS16280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM417_RS16285	COG0628	permease
KM417_RS16305	COG2226	methyltransferase
KM417_RS16315	COG0477	Major facilitator Superfamily
KM417_RS16345	COG1253	flavin adenine dinucleotide binding
KM417_RS16350	COG0789	Transcriptional regulator
KM417_RS16355	COG0697	spore germination
KM417_RS16360	COG1357	PFAM Pentapeptide repeats (8 copies)
KM417_RS16365	COG3813	Protein conserved in bacteria
KM417_RS16370	COG2706	6-phosphogluconolactonase activity
KM417_RS16375	COG1070	Carbohydrate kinase
KM417_RS16385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM417_RS16390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM417_RS16400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM417_RS16405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM417_RS16410	COG0604	alcohol dehydrogenase
KM417_RS16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_RS16425	COG0604	alcohol dehydrogenase
KM417_RS16425	COG3321	synthase
KM417_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS16455	COG0656	L-ascorbic acid biosynthetic process
KM417_RS16460	COG2814	Major facilitator Superfamily
KM417_RS16475	COG0346	lactoylglutathione lyase activity
KM417_RS16480	COG0814	amino acid
KM417_RS16505	COG1393	Belongs to the ArsC family
KM417_RS16510	COG1733	regulation of RNA biosynthetic process
KM417_RS16515	COG2188	Transcriptional regulator
KM417_RS16525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM417_RS16530	COG1733	regulation of RNA biosynthetic process
KM417_RS16535	COG1733	regulation of RNA biosynthetic process
KM417_RS16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS16570	COG0384	phenazine biosynthesis protein PhzF
KM417_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS16590	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS16600	COG1733	regulation of RNA biosynthetic process
KM417_RS16630	COG1191	sigma factor activity
KM417_RS16645	COG1309	transcriptional regulator
KM417_RS16665	COG3152	Membrane
KM417_RS16690	COG1151	hydroxylamine reductase activity
KM417_RS16700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS16705	COG3757	hydrolase, family 25
KM417_RS16705	COG3409	Peptidoglycan-binding domain 1 protein
KM417_RS16740	COG2072	flavoprotein involved in K transport
KM417_RS16775	COG0604	alcohol dehydrogenase
KM417_RS16780	COG1113	amino acid transport
KM417_RS16785	COG2814	Major facilitator Superfamily
KM417_RS16815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_RS16820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_RS16845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS16850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS16855	COG3739	integral membrane protein
KM417_RS16860	COG0384	phenazine biosynthesis protein PhzF
KM417_RS16890	COG0583	DNA-binding transcription factor activity
KM417_RS16910	COG1193	negative regulation of DNA recombination
KM417_RS16935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_RS16965	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_RS16990	COG0640	Transcriptional regulator
KM417_RS16995	COG0604	alcohol dehydrogenase
KM417_RS17015	COG2808	Putative FMN-binding domain
KM417_RS17020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_RS17030	COG0385	Bile acid
KM417_RS17035	COG0277	FAD linked oxidase domain protein
KM417_RS17065	COG1216	Glycosyl transferase, family 2
KM417_RS17070	COG1024	Enoyl-CoA hydratase
KM417_RS17080	COG1285	pathogenesis
KM417_RS17095	COG2514	catechol 2,3-dioxygenase activity
KM417_RS17100	COG2720	vancomycin resistance protein
KM417_RS17140	COG0716	FMN binding
KM417_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS17180	COG0165	Argininosuccinate lyase
KM417_RS17195	COG4145	pantothenate transmembrane transporter activity
KM417_RS17205	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS17210	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS17220	COG1657	PFAM Prenyltransferase squalene oxidase
KM417_RS17225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM417_RS17230	COG2962	Rard protein
KM417_RS17235	COG3326	Membrane
KM417_RS17250	COG0489	protein tyrosine kinase activity
KM417_RS17260	COG0314	molybdopterin synthase activity
KM417_RS17265	COG0303	'Molybdopterin
KM417_RS17270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_RS17275	COG2116	formate transmembrane transporter activity
KM417_RS17285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM417_RS17290	COG5609	conserved protein (DUF2294)
KM417_RS17295	COG2427	Protein of unknown function (DUF1641)
KM417_RS17300	COG3383	formate dehydrogenase (NAD+) activity
KM417_RS17310	COG0697	spore germination
KM417_RS17350	COG2226	methyltransferase
KM417_RS17355	COG4166	transmembrane transport
KM417_RS17360	COG4166	transmembrane transport
KM417_RS17365	COG4166	transmembrane transport
KM417_RS17370	COG1301	dicarboxylic acid transport
KM417_RS17375	COG1316	TRANSCRIPTIONal
KM417_RS17385	COG1595	DNA-templated transcription, initiation
KM417_RS17405	COG1131	(ABC) transporter
KM417_RS17415	COG0673	inositol 2-dehydrogenase activity
KM417_RS17420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM417_RS17425	COG0187	DNA topoisomerase II activity
KM417_RS17430	COG1832	CoA-binding protein
KM417_RS17435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_RS17440	COG0745	RESPONSE REGULATOR receiver
KM417_RS17455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_RS17460	COG4841	protein insertion into membrane
KM417_RS17465	COG0824	Thioesterase
KM417_RS17495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_RS17505	COG2274	protein secretion by the type I secretion system
KM417_RS17510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM417_RS17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_RS17565	COG0183	Belongs to the thiolase family
KM417_RS17570	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS17575	COG1268	BioY protein
KM417_RS17580	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS17630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS17640	COG5002	protein histidine kinase activity
KM417_RS17645	COG0400	carboxylic ester hydrolase activity
KM417_RS17650	COG0346	lactoylglutathione lyase activity
KM417_RS17655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_RS17660	COG0069	glutamate synthase activity
KM417_RS17665	COG1902	pentaerythritol trinitrate reductase activity
KM417_RS17670	COG1329	Transcriptional regulator
KM417_RS17675	COG0010	Belongs to the arginase family
KM417_RS17700	COG2226	methyltransferase
KM417_RS17735	COG4846	Membrane protein involved in cytochrome C biogenesis
KM417_RS17740	COG0785	Cytochrome C biogenesis protein
KM417_RS17750	COG0583	DNA-binding transcription factor activity
KM417_RS17755	COG1380	Effector of murein hydrolase LrgA
KM417_RS17760	COG1346	cytolysis
KM417_RS17785	COG3409	Peptidoglycan-binding domain 1 protein
KM417_RS17785	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM417_RS17800	COG1132	(ABC) transporter
KM417_RS17805	COG1132	(ABC) transporter
KM417_RS17835	COG3639	organic phosphonate transmembrane transporter activity
KM417_RS17840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM417_RS17860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM417_RS17880	COG1695	Transcriptional regulator
KM417_RS17920	COG1388	LysM domain
KM417_RS17920	COG3409	Peptidoglycan-binding domain 1 protein
KM417_RS17920	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM417_RS17925	COG4824	toxin secretion phage lysis holin
KM417_RS18080	COG1595	DNA-templated transcription, initiation
KM417_RS18125	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM417_RS18205	COG1396	sequence-specific DNA binding
KM417_RS18230	COG0174	glutamine synthetase
KM417_RS18235	COG0789	Transcriptional regulator
KM417_RS18240	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM417_RS18250	COG2860	membrane
KM417_RS18255	COG0464	growth
KM417_RS18285	COG3584	3D domain protein
KM417_RS18285	COG1388	LysM domain
KM417_RS18290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM417_RS18290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM417_RS18290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_RS18295	COG1105	Belongs to the carbohydrate kinase PfkB family
KM417_RS18300	COG1349	DNA-binding transcription factor activity
KM417_RS18310	COG2322	membrane
KM417_RS18320	COG1113	amino acid transport
KM417_RS18335	COG1408	metallophosphoesterase
KM417_RS18340	COG2116	formate transmembrane transporter activity
KM417_RS18350	COG2217	Heavy metal translocating P-type atpase
KM417_RS18355	COG2608	mercury ion transmembrane transporter activity
KM417_RS18360	COG1937	Protein conserved in bacteria
KM417_RS18370	COG2819	hydrolase of the alpha beta superfamily
KM417_RS18375	COG1120	ATPase activity
KM417_RS18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS18395	COG0708	Exodeoxyribonuclease III
KM417_RS18400	COG2169	Transcriptional regulator
KM417_RS18405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM417_RS18410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM417_RS18420	COG2364	Membrane
KM417_RS18435	COG2267	carboxylic ester hydrolase activity
KM417_RS18440	COG0346	lactoylglutathione lyase activity
KM417_RS18445	COG3300	MHYT domain
KM417_RS18445	COG5001	Diguanylate cyclase
KM417_RS18465	COG1346	cytolysis
KM417_RS18470	COG1380	Effector of murein hydrolase LrgA
KM417_RS18475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_RS18480	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_RS18480	COG0596	Alpha beta hydrolase
KM417_RS18485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_RS18505	COG1404	Belongs to the peptidase S8 family
KM417_RS18510	COG3773	Cell wall hydrolase
KM417_RS18515	COG0562	UDP-galactopyranose mutase
KM417_RS18520	COG1368	sulfuric ester hydrolase activity
KM417_RS18525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_RS18535	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM417_RS18560	COG1131	(ABC) transporter
KM417_RS18580	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM417_RS18585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM417_RS18590	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM417_RS18595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM417_RS18595	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM417_RS18605	COG2359	stage V sporulation protein S
KM417_RS18610	COG1692	metallophosphoesterase
KM417_RS18635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM417_RS18640	COG1426	Protein conserved in bacteria
KM417_RS18655	COG0300	oxidoreductase activity
KM417_RS18660	COG0612	Peptidase, M16
KM417_RS18665	COG0612	Peptidase, M16
KM417_RS18670	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM417_RS18680	COG3845	ABC transporter
KM417_RS18685	COG1744	ABC transporter substrate-binding protein PnrA-like
KM417_RS18690	COG2188	Transcriptional regulator
KM417_RS18695	COG1674	ftsk spoiiie
KM417_RS18705	COG0740	serine-type endopeptidase activity
KM417_RS18710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_RS18720	COG0527	aspartate kinase activity
KM417_RS18725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM417_RS18730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM417_RS18735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM417_RS18740	COG1873	PFAM PRC-barrel domain
KM417_RS18745	COG0612	Peptidase, M16
KM417_RS18750	COG0726	polysaccharide deacetylase
KM417_RS18765	COG0196	riboflavin kinase activity
KM417_RS18770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM417_RS18780	COG1550	Protein conserved in bacteria
KM417_RS18790	COG1358	cellular component organization or biogenesis
KM417_RS18795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM417_RS18800	COG0195	Participates in both transcription termination and antitermination
KM417_RS18820	COG0750	zinc metalloprotease
KM417_RS18830	COG4589	Belongs to the CDS family
KM417_RS18835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM417_RS18845	COG0528	UMP kinase activity
KM417_RS18875	COG4974	Belongs to the 'phage' integrase family
KM417_RS18885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM417_RS18895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM417_RS18935	COG1837	Belongs to the UPF0109 family
KM417_RS18945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM417_RS18955	COG0552	protein localization to endoplasmic reticulum
KM417_RS18960	COG1196	nuclear chromosome segregation
KM417_RS18970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_RS18975	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS18980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM417_RS18995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM417_RS19000	COG1461	Dihydroxyacetone kinase
KM417_RS19005	COG1302	Protein conserved in bacteria
KM417_RS19020	COG1564	THIamine pyrophosphokinase
KM417_RS19025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM417_RS19030	COG1162	GTPase activity
KM417_RS19035	COG0515	serine threonine protein kinase
KM417_RS19035	COG2815	serine threonine protein kinase
KM417_RS19040	COG0631	protein serine/threonine phosphatase activity
KM417_RS19050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM417_RS19050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM417_RS19060	COG0242	peptide deformylase activity
KM417_RS19065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM417_RS19070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM417_RS19090	COG1561	YicC-like family, N-terminal region
KM417_RS19095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM417_RS19105	COG0006	proline dipeptidase activity
KM417_RS19120	COG3069	C4-dicarboxylate transmembrane transporter activity
KM417_RS19185	COG0564	pseudouridine synthase activity
KM417_RS19205	COG3599	regulation of cell shape
KM417_RS19210	COG2302	S4 RNA-binding domain
KM417_RS19215	COG0762	integral membrane protein
KM417_RS19225	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM417_RS19230	COG1496	oxidoreductase activity
KM417_RS19235	COG1873	PFAM PRC-barrel domain
KM417_RS19240	COG1191	sigma factor activity
KM417_RS19245	COG1191	sigma factor activity
KM417_RS19255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM417_RS19260	COG0849	cell division
KM417_RS19265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM417_RS19270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM417_RS19280	COG0772	Belongs to the SEDS family
KM417_RS19295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM417_RS19300	COG0768	penicillin binding
KM417_RS19305	COG0768	penicillin binding
KM417_RS19310	COG4839	cell division protein FtsL
KM417_RS19325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM417_RS19340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM417_RS19345	COG1399	metal-binding, possibly nucleic acid-binding protein
KM417_RS19395	COG4824	toxin secretion phage lysis holin
KM417_RS19490	COG1802	Transcriptional regulator
KM417_RS19490	COG4626	Terminase
KM417_RS19515	COG0582	viral genome integration into host DNA
KM417_RS19580	COG0756	dUTP diphosphatase activity
KM417_RS19595	COG1191	sigma factor activity
KM417_RS19620	COG1484	DNA-dependent DNA replication
KM417_RS19650	COG1396	sequence-specific DNA binding
KM417_RS19665	COG1396	sequence-specific DNA binding
KM417_RS19680	COG0582	viral genome integration into host DNA
KM417_RS19690	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM417_RS19695	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM417_RS19700	COG3314	Sporulation integral membrane protein YlbJ
KM417_RS19710	COG0742	ribosomal rna small subunit methyltransferase
KM417_RS19725	COG3679	Belongs to the UPF0342 family
KM417_RS19730	COG0406	alpha-ribazole phosphatase activity
KM417_RS19745	COG2340	Cysteine-rich secretory protein family
KM417_RS19760	COG3336	cytochrome c oxidase
KM417_RS19795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM417_RS19800	COG0772	Belongs to the SEDS family
KM417_RS19810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM417_RS19815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM417_RS19825	COG4896	Protein conserved in bacteria
KM417_RS19840	COG1217	gtp-binding protein TYPA
KM417_RS19850	COG0483	inositol monophosphate 1-phosphatase activity
KM417_RS19870	COG1982	Orn Lys Arg decarboxylase major
KM417_RS19915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_RS19920	COG0022	dehydrogenase e1 component
KM417_RS19925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_RS19935	COG0242	peptide deformylase activity
KM417_RS19940	COG0561	phosphatase activity
KM417_RS19950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_RS19955	COG0569	domain protein
KM417_RS19975	COG0583	DNA-binding transcription factor activity
KM417_RS19980	COG0517	IMP dehydrogenase activity
KM417_RS19990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM417_RS20000	COG4703	Protein of unknown function (DUF1797)
KM417_RS20015	COG2200	EAL domain
KM417_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS20025	COG1408	metallophosphoesterase
KM417_RS20035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM417_RS20070	COG2814	Major facilitator Superfamily
KM417_RS20090	COG3209	COG3209 Rhs family protein
KM417_RS20100	COG2205	protein histidine kinase activity
KM417_RS20110	COG0436	Aminotransferase
KM417_RS20115	COG1609	Transcriptional regulator
KM417_RS20120	COG3833	ABC-type maltose transport systems, permease component
KM417_RS20125	COG1175	transmembrane transport
KM417_RS20130	COG2182	Extracellular solute-binding protein
KM417_RS20140	COG0366	Alpha amylase catalytic
KM417_RS20145	COG3842	ATPase activity
KM417_RS20185	COG0183	Belongs to the thiolase family
KM417_RS20220	COG1695	Transcriptional regulator
KM417_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS20235	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM417_RS20245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM417_RS20250	COG0436	Aminotransferase
KM417_RS20270	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM417_RS20290	COG2199	diguanylate cyclase activity
KM417_RS20295	COG0778	Nitroreductase
KM417_RS20320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_RS20320	COG2190	(PTS) system
KM417_RS20320	COG1263	PTS System
KM417_RS20325	COG3711	transcriptional antiterminator
KM417_RS20335	COG2188	Transcriptional regulator
KM417_RS20345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM417_RS20370	COG1547	Domain of unknown function (DUF309)
KM417_RS20375	COG0456	acetyltransferase
KM417_RS20385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM417_RS20390	COG4086	secreted protein
KM417_RS20395	COG0561	phosphatase activity
KM417_RS20400	COG0697	spore germination
KM417_RS20415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS20440	COG0733	neurotransmitter:sodium symporter activity
KM417_RS20460	COG1686	Belongs to the peptidase S11 family
KM417_RS20465	COG1725	Transcriptional regulator
KM417_RS20470	COG1131	(ABC) transporter
KM417_RS20485	COG1846	Transcriptional regulator
KM417_RS20500	COG0598	Magnesium transport protein CorA
KM417_RS20525	COG4974	Belongs to the 'phage' integrase family
KM417_RS20535	COG0735	belongs to the Fur family
KM417_RS20540	COG1300	Membrane
KM417_RS20560	COG0667	Aldo Keto reductase
KM417_RS20565	COG0656	L-ascorbic acid biosynthetic process
KM417_RS20570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_RS20570	COG0456	acetyltransferase
KM417_RS20580	COG0737	Belongs to the 5'-nucleotidase family
KM417_RS20580	COG1525	nuclease
KM417_RS20580	COG4085	toxin activity
KM417_RS20590	COG0596	Alpha beta hydrolase
KM417_RS20595	COG2056	Na+-H+ antiporter family
KM417_RS20600	COG1609	Transcriptional regulator
KM417_RS20605	COG0456	acetyltransferase
KM417_RS20610	COG1073	alpha beta
KM417_RS20625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM417_RS20625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM417_RS20630	COG0307	riboflavin synthase, alpha
KM417_RS20655	COG4106	trans-aconitate 2-methyltransferase activity
KM417_RS20660	COG2226	methyltransferase
KM417_RS20660	COG1073	alpha beta
KM417_RS20675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_RS20685	COG1757	Na H antiporter
KM417_RS20690	COG0737	Belongs to the 5'-nucleotidase family
KM417_RS20700	COG1522	sequence-specific DNA binding
KM417_RS20720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM417_RS20730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM417_RS20745	COG0300	oxidoreductase activity
KM417_RS20755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_RS20760	COG1760	l-serine dehydratase
KM417_RS20765	COG1760	l-serine dehydratase
KM417_RS20785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_RS20795	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM417_RS20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS20815	COG1376	ErfK ybiS ycfS ynhG family protein
KM417_RS20820	COG4129	membrane
KM417_RS20825	COG1126	abc transporter atp-binding protein
KM417_RS20830	COG0765	amino acid transport
KM417_RS20835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_RS20850	COG2816	NAD+ diphosphatase activity
KM417_RS20855	COG0772	Belongs to the SEDS family
KM417_RS20860	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_RS20865	COG0022	dehydrogenase e1 component
KM417_RS20870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_RS20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM417_RS20890	COG0280	phosphate acetyltransferase
KM417_RS20895	COG3290	protein histidine kinase activity
KM417_RS20895	COG3829	transcription factor binding
KM417_RS20905	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_RS20910	COG3093	addiction module antidote protein HigA
KM417_RS20920	COG0745	RESPONSE REGULATOR receiver
KM417_RS20925	COG0750	zinc metalloprotease
KM417_RS20930	COG0497	DNA recombination
KM417_RS20940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM417_RS20950	COG0142	geranyltranstransferase activity
KM417_RS20975	COG1302	Protein conserved in bacteria
KM417_RS20980	COG0439	Biotin carboxylase
KM417_RS20985	COG0511	ligase activity, forming carbon-carbon bonds
KM417_RS21030	COG3854	ATPases associated with a variety of cellular activities
KM417_RS21055	COG0006	proline dipeptidase activity
KM417_RS21070	COG3872	metal-dependent enzyme
KM417_RS21080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM417_RS21100	COG0095	Lipoate-protein ligase
KM417_RS21105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_RS21110	COG1609	Transcriptional regulator
KM417_RS21120	COG2076	Multidrug Resistance protein
KM417_RS21125	COG2076	Multidrug Resistance protein
KM417_RS21160	COG1131	(ABC) transporter
KM417_RS21165	COG1725	Transcriptional regulator
KM417_RS21195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_RS21250	COG4970	Tfp pilus assembly protein FimT
KM417_RS21260	COG1459	type II secretion system
KM417_RS21265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM417_RS21315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM417_RS21320	COG0646	methionine synthase
KM417_RS21320	COG1410	methionine synthase
KM417_RS21325	COG0646	methionine synthase
KM417_RS21325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM417_RS21330	COG0626	cystathionine gamma-synthase activity
KM417_RS21335	COG0626	cystathionine gamma-synthase activity
KM417_RS21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS21365	COG1940	carbohydrate kinase activity
KM417_RS21370	COG4483	Protein conserved in bacteria
KM417_RS21375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM417_RS21380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM417_RS21385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM417_RS21390	COG0704	Plays a role in the regulation of phosphate uptake
KM417_RS21400	COG0581	inorganic phosphate transmembrane transporter activity
KM417_RS21405	COG0573	inorganic phosphate transmembrane transporter activity
KM417_RS21410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM417_RS21415	COG0768	penicillin binding
KM417_RS21420	COG0477	Major facilitator Superfamily
KM417_RS21425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_RS21450	COG0735	belongs to the Fur family
KM417_RS21455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM417_RS21460	COG1121	(ABC) transporter
KM417_RS21465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS21495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM417_RS21500	COG2384	SAM-dependent methyltransferase
KM417_RS21505	COG2010	Cytochrome c
KM417_RS21510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM417_RS21515	COG0358	DNA primase activity
KM417_RS21525	COG0517	IMP dehydrogenase activity
KM417_RS21540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM417_RS21545	COG0295	cytidine deaminase activity
KM417_RS21550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM417_RS21560	COG1480	7TM receptor with intracellular HD hydrolase
KM417_RS21565	COG1702	phosphate starvation-inducible protein PhoH
KM417_RS21580	COG1610	YqeY-like protein
KM417_RS21585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM417_RS21590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM417_RS21595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM417_RS21625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM417_RS21630	COG1733	regulation of RNA biosynthetic process
KM417_RS21655	COG1466	dna polymerase III delta subunit
KM417_RS21665	COG2333	competence protein COMEC
KM417_RS21665	COG0658	competence protein
KM417_RS21670	COG2131	deaminase
KM417_RS21675	COG1555	photosystem II stabilization
KM417_RS21675	COG1596	polysaccharide export
KM417_RS21680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_RS21685	COG2226	methyltransferase
KM417_RS21690	COG0799	negative regulation of ribosome biogenesis
KM417_RS21695	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM417_RS21705	COG1534	Rna-binding protein
KM417_RS21715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM417_RS21720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM417_RS21745	COG1595	DNA-templated transcription, initiation
KM417_RS21755	COG0778	Nitroreductase
KM417_RS21760	COG2357	RelA SpoT domain protein
KM417_RS21770	COG1785	Belongs to the alkaline phosphatase family
KM417_RS21780	COG2267	carboxylic ester hydrolase activity
KM417_RS21815	COG1404	Belongs to the peptidase S8 family
KM417_RS21820	COG3186	Phenylalanine-4-hydroxylase
KM417_RS21835	COG2259	Doxx family
KM417_RS21875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS21885	COG1454	alcohol dehydrogenase
KM417_RS21885	COG1012	belongs to the aldehyde dehydrogenase family
KM417_RS21890	COG0626	cystathionine gamma-synthase activity
KM417_RS21895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_RS21920	COG0768	penicillin binding
KM417_RS21935	COG0826	peptidase U32
KM417_RS21940	COG0826	peptidase U32
KM417_RS21945	COG4122	O-methyltransferase activity
KM417_RS21950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM417_RS21970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_RS21980	COG0628	permease
KM417_RS22000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM417_RS22010	COG0482	sulfurtransferase activity
KM417_RS22015	COG1104	cysteine desulfurase activity
KM417_RS22020	COG1959	2 iron, 2 sulfur cluster binding
KM417_RS22025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM417_RS22035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM417_RS22060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM417_RS22070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM417_RS22070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM417_RS22075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM417_RS22080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM417_RS22080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM417_RS22090	COG2244	polysaccharide biosynthetic process
KM417_RS22095	COG2323	membrane
KM417_RS22105	COG1862	Preprotein translocase
KM417_RS22135	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM417_RS22145	COG0697	spore germination
KM417_RS22150	COG0697	spore germination
KM417_RS22155	COG0640	Transcriptional regulator
KM417_RS22180	COG0157	Belongs to the NadC ModD family
KM417_RS22185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM417_RS22190	COG1104	cysteine desulfurase activity
KM417_RS22195	COG1827	regulation of RNA biosynthetic process
KM417_RS22200	COG2258	MOSC domain
KM417_RS22205	COG0077	Prephenate dehydratase
KM417_RS22210	COG0577	efflux transmembrane transporter activity
KM417_RS22215	COG0577	efflux transmembrane transporter activity
KM417_RS22220	COG1136	(ABC) transporter
KM417_RS22230	COG0745	RESPONSE REGULATOR receiver
KM417_RS22235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM417_RS22240	COG3290	protein histidine kinase activity
KM417_RS22250	COG2868	ribosomal protein
KM417_RS22260	COG1530	ribonuclease E activity
KM417_RS22265	COG1994	Peptidase M50
KM417_RS22270	COG0739	heme binding
KM417_RS22275	COG2894	cell division
KM417_RS22295	COG1077	Cell shape determining protein MreB Mrl
KM417_RS22315	COG0285	dihydrofolate synthase activity
KM417_RS22320	COG0525	valine-tRNA ligase activity
KM417_RS22330	COG1388	LysM domain
KM417_RS22340	COG0113	porphobilinogen synthase activity
KM417_RS22345	COG1587	Uroporphyrinogen-III synthase
KM417_RS22355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM417_RS22365	COG1846	Transcriptional regulator
KM417_RS22370	COG1764	response to oxidative stress
KM417_RS22385	COG0470	DNA polymerase III
KM417_RS22385	COG1067	ATP-dependent peptidase activity
KM417_RS22430	COG0622	Phosphoesterase
KM417_RS22445	COG5401	PFAM Sporulation and spore germination
KM417_RS22465	COG1309	transcriptional regulator
KM417_RS22480	COG2197	response regulator
KM417_RS22485	COG2233	PERMEase
KM417_RS22495	COG0402	S-adenosylhomocysteine deaminase activity
KM417_RS22500	COG0402	S-adenosylhomocysteine deaminase activity
KM417_RS22510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_RS22520	COG0444	Belongs to the ABC transporter superfamily
KM417_RS22525	COG4608	Belongs to the ABC transporter superfamily
KM417_RS22530	COG3275	phosphorelay sensor kinase activity
KM417_RS22535	COG3279	Response regulator of the LytR AlgR family
KM417_RS22550	COG1983	PspC domain protein
KM417_RS22555	COG1396	sequence-specific DNA binding
KM417_RS22560	COG0697	spore germination
KM417_RS22570	COG1959	2 iron, 2 sulfur cluster binding
KM417_RS22575	COG1668	transmembrane transport
KM417_RS22580	COG4152	abc transporter atp-binding protein
KM417_RS22585	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM417_RS22595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM417_RS22600	COG1876	peptidase activity
KM417_RS22605	COG0824	Thioesterase
KM417_RS22610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM417_RS22615	COG1053	succinate dehydrogenase
KM417_RS22620	COG2009	succinate dehydrogenase
KM417_RS22625	COG1719	4-vinyl reductase, 4VR
KM417_RS22635	COG3118	belongs to the thioredoxin family
KM417_RS22640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM417_RS22645	COG2086	electron transfer activity
KM417_RS22650	COG1024	Enoyl-CoA hydratase
KM417_RS22660	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_RS22680	COG2318	DinB family
KM417_RS22710	COG1131	(ABC) transporter
KM417_RS22715	COG2205	protein histidine kinase activity
KM417_RS22720	COG0745	RESPONSE REGULATOR receiver
KM417_RS22730	COG4895	conserved protein (DUF2196)
KM417_RS22735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM417_RS22750	COG4509	Sortase family
KM417_RS22755	COG1120	ATPase activity
KM417_RS22770	COG5386	Cell surface protein
KM417_RS22780	COG5386	Cell surface protein
KM417_RS22785	COG1114	Component of the transport system for branched-chain amino acids
KM417_RS22790	COG1187	pseudouridine synthase activity
KM417_RS22800	COG1796	DNA polymerase
KM417_RS22800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM417_RS22805	COG1286	toxin biosynthetic process
KM417_RS22850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM417_RS22860	COG1418	mRNA catabolic process
KM417_RS22885	COG2814	Major facilitator Superfamily
KM417_RS22890	COG1566	PFAM secretion protein HlyD family protein
KM417_RS22895	COG1309	transcriptional regulator
KM417_RS22900	COG1363	Peptidase, m42
KM417_RS22925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_RS22935	COG1484	DNA-dependent DNA replication
KM417_RS22940	COG3611	Membrane attachment protein
KM417_RS22950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM417_RS22955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM417_RS22960	COG0237	dephospho-CoA kinase activity
KM417_RS22965	COG1971	Probably functions as a manganese efflux pump
KM417_RS22975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_RS22975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_RS22980	COG5002	protein histidine kinase activity
KM417_RS22985	COG0745	RESPONSE REGULATOR receiver
KM417_RS23005	COG0538	isocitrate dehydrogenase activity
KM417_RS23010	COG0372	Belongs to the citrate synthase family
KM417_RS23020	COG0628	permease
KM417_RS23025	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM417_RS23050	COG1725	Transcriptional regulator
KM417_RS23055	COG0281	malic enzyme
KM417_RS23060	COG0587	DNA-directed DNA polymerase activity
KM417_RS23075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM417_RS23095	COG4109	DRTGG domain
KM417_RS23110	COG0006	proline dipeptidase activity
KM417_RS23150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS23155	COG0662	Cupin 2, conserved barrel domain protein
KM417_RS23165	COG1476	TRANSCRIPTIONal
KM417_RS23180	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_RS23185	COG0589	response to stress
KM417_RS23225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS23245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM417_RS23250	COG0827	DNA restriction-modification system
KM417_RS23255	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM417_RS23260	COG3874	Sporulation protein YtfJ
KM417_RS23275	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM417_RS23285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_RS23300	COG1104	cysteine desulfurase activity
KM417_RS23310	COG0583	DNA-binding transcription factor activity
KM417_RS23315	COG0697	spore germination
KM417_RS23325	COG1956	GAF domain-containing protein
KM417_RS23330	COG0626	cystathionine gamma-synthase activity
KM417_RS23360	COG1595	DNA-templated transcription, initiation
KM417_RS23370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_RS23375	COG0454	-acetyltransferase
KM417_RS23380	COG0517	IMP dehydrogenase activity
KM417_RS23385	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM417_RS23395	COG0745	RESPONSE REGULATOR receiver
KM417_RS23405	COG0666	response to abiotic stimulus
KM417_RS23440	COG1609	Transcriptional regulator
KM417_RS23445	COG4851	CamS sex pheromone cAM373 precursor
KM417_RS23450	COG3118	belongs to the thioredoxin family
KM417_RS23460	COG2309	aminopeptidase activity
KM417_RS23480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS23495	COG1674	ftsk spoiiie
KM417_RS23505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_RS23510	COG4848	Belongs to the UPF0354 family
KM417_RS23515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_RS23520	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM417_RS23525	COG1363	Peptidase, m42
KM417_RS23535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS23550	COG0510	thiamine kinase activity
KM417_RS23555	COG1523	belongs to the glycosyl hydrolase 13 family
KM417_RS23570	COG1349	DNA-binding transcription factor activity
KM417_RS23575	COG1187	pseudouridine synthase activity
KM417_RS23580	COG2244	polysaccharide biosynthetic process
KM417_RS23585	COG2081	HI0933 family
KM417_RS23590	COG2814	Major facilitator Superfamily
KM417_RS23600	COG3832	glyoxalase III activity
KM417_RS23620	COG1329	Transcriptional regulator
KM417_RS23630	COG4975	Glucose uptake
KM417_RS23645	COG0314	molybdopterin synthase activity
KM417_RS23650	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM417_RS23655	COG0303	'Molybdopterin
KM417_RS23665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_RS23690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_RS23700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM417_RS23740	COG2814	Major facilitator Superfamily
KM417_RS23745	COG0475	glutathione-regulated potassium exporter activity
KM417_RS23750	COG0490	domain, Protein
KM417_RS23755	COG0582	viral genome integration into host DNA
KM417_RS23765	COG1136	(ABC) transporter
KM417_RS23785	COG1242	4 iron, 4 sulfur cluster binding
KM417_RS23790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM417_RS23795	COG1131	(ABC) transporter
KM417_RS23805	COG1794	racemase activity, acting on amino acids and derivatives
KM417_RS23825	COG2267	carboxylic ester hydrolase activity
KM417_RS23835	COG0671	phosphoesterase, PA-phosphatase related
KM417_RS23840	COG0438	transferase activity, transferring glycosyl groups
KM417_RS23850	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM417_RS23905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM417_RS23910	COG5002	protein histidine kinase activity
KM417_RS23915	COG4191	Histidine kinase
KM417_RS23920	COG2267	carboxylic ester hydrolase activity
KM417_RS23940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_RS23945	COG1116	anion transmembrane transporter activity
KM417_RS23950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_RS23975	COG0494	nUDIX hydrolase
KM417_RS24010	COG0288	reversible hydration of carbon dioxide
KM417_RS24015	COG1271	oxidase subunit
KM417_RS24020	COG1294	oxidase, subunit
KM417_RS24040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS24065	COG1842	Phage shock protein A
KM417_RS24095	COG5002	protein histidine kinase activity
KM417_RS24100	COG0745	RESPONSE REGULATOR receiver
KM417_RS24130	COG1597	lipid kinase activity
KM417_RS24165	COG0586	Pfam SNARE associated Golgi protein
KM417_RS24175	COG0577	efflux transmembrane transporter activity
KM417_RS24180	COG1136	(ABC) transporter
KM417_RS24185	COG3708	Transcriptional regulator
KM417_RS24185	COG2207	Transcriptional regulator
KM417_RS24190	COG0745	RESPONSE REGULATOR receiver
KM417_RS24195	COG2205	protein histidine kinase activity
KM417_RS24205	COG0577	efflux transmembrane transporter activity
KM417_RS24210	COG1136	(ABC) transporter
KM417_RS24230	COG2188	Transcriptional regulator
KM417_RS24250	COG3964	amidohydrolase
KM417_RS24280	COG4948	Mandelate Racemase Muconate Lactonizing
KM417_RS24290	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM417_RS24295	COG0596	Alpha beta hydrolase
KM417_RS24300	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM417_RS24305	COG1169	isochorismate synthase
KM417_RS24310	COG1575	Belongs to the MenA family. Type 1 subfamily
KM417_RS24315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM417_RS24335	COG0058	SHG alpha-glucan phosphorylase activity
KM417_RS24340	COG0297	glycogen (starch) synthase activity
KM417_RS24345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM417_RS24460	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM417_RS24495	COG1285	pathogenesis
KM417_RS24500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM417_RS24510	COG0166	Belongs to the GPI family
KM417_RS24515	COG2155	Conserved Protein
KM417_RS24520	COG1098	S1 RNA binding domain
KM417_RS24525	COG0436	Aminotransferase
KM417_RS24530	COG1522	sequence-specific DNA binding
KM417_RS24535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM417_RS24540	COG2267	carboxylic ester hydrolase activity
KM417_RS24550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM417_RS24570	COG5018	Exonuclease
KM417_RS24575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_RS24595	COG2050	protein possibly involved in aromatic compounds catabolism
KM417_RS24605	COG1268	BioY protein
KM417_RS24615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM417_RS24620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM417_RS24635	COG3584	3D domain protein
KM417_RS24650	COG1252	NADH dehydrogenase
KM417_RS24665	COG3708	Transcriptional regulator
KM417_RS24680	COG1683	Conserved Protein
KM417_RS24700	COG0316	Belongs to the HesB IscA family
KM417_RS24715	COG1252	NADH dehydrogenase
KM417_RS24730	COG0390	transport system, permease component
KM417_RS24735	COG2824	Alkylphosphonate utilization operon protein PhnA
KM417_RS24775	COG4837	Protein of unknown function (DUF1462)
KM417_RS24780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM417_RS24790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_RS24795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM417_RS24805	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_RS24810	COG0647	UMP catabolic process
KM417_RS24820	COG2445	Protein of unknown function DUF86
KM417_RS24825	COG1494	fructose-1,6-bisphosphatase
KM417_RS24840	COG4470	Protein conserved in bacteria
KM417_RS24850	COG0789	Transcriptional regulator
KM417_RS24855	COG4377	Putative membrane peptidase family (DUF2324)
KM417_RS24880	COG0739	heme binding
KM417_RS24890	COG3377	Domain of unknown function (DUF1805)
KM417_RS24895	COG0737	Belongs to the 5'-nucleotidase family
KM417_RS24900	COG1695	Transcriptional regulator
KM417_RS24910	COG0719	Fe-S assembly protein
KM417_RS24915	COG0822	iron-sulfur transferase activity
KM417_RS24920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM417_RS24925	COG0719	Fe-S assembly protein
KM417_RS24930	COG0396	ATPase activity
KM417_RS24935	COG1464	Belongs to the NlpA lipoprotein family
KM417_RS24940	COG1464	Belongs to the NlpA lipoprotein family
KM417_RS24945	COG2011	ABC-type metal ion transport system permease component
KM417_RS24950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_RS24960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_RS24965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM417_RS24975	COG1393	Belongs to the ArsC family
KM417_RS25020	COG0039	L-malate dehydrogenase activity
KM417_RS25045	COG1309	transcriptional regulator
KM417_RS25050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_RS25055	COG1960	acyl-CoA dehydrogenase activity
KM417_RS25060	COG0183	Belongs to the thiolase family
KM417_RS25065	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM417_RS25065	COG1024	Enoyl-CoA hydratase
KM417_RS25075	COG1686	Belongs to the peptidase S11 family
KM417_RS25090	COG0011	TIGRFAM Protein of
KM417_RS25095	COG0840	transmembrane signaling receptor activity
KM417_RS25115	COG2814	Major facilitator Superfamily
KM417_RS25120	COG0531	amino acid
KM417_RS25130	COG0706	membrane insertase activity
KM417_RS25140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_RS25175	COG0586	Pfam SNARE associated Golgi protein
KM417_RS25185	COG1376	ErfK ybiS ycfS ynhG family protein
KM417_RS25190	COG0745	RESPONSE REGULATOR receiver
KM417_RS25195	COG5002	protein histidine kinase activity
KM417_RS25220	COG2151	metal-sulfur cluster biosynthetic enzyme
KM417_RS25225	COG3227	Zinc metalloprotease (Elastase)
KM417_RS25230	COG1741	Belongs to the pirin family
KM417_RS25245	COG0475	glutathione-regulated potassium exporter activity
KM417_RS25250	COG0490	domain, Protein
KM417_RS25255	COG1115	amino acid carrier protein
KM417_RS25260	COG0783	Belongs to the Dps family
KM417_RS25275	COG1611	Belongs to the LOG family
KM417_RS25295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS25300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS25305	COG1115	amino acid carrier protein
KM417_RS25310	COG1115	amino acid carrier protein
KM417_RS25315	COG2910	NAD(P)H-binding
KM417_RS25330	COG0656	L-ascorbic acid biosynthetic process
KM417_RS25335	COG2814	Major facilitator Superfamily
KM417_RS25340	COG1733	regulation of RNA biosynthetic process
KM417_RS25350	COG1252	NADH dehydrogenase
KM417_RS25355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM417_RS25360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM417_RS25370	COG0840	transmembrane signaling receptor activity
KM417_RS25370	COG3290	protein histidine kinase activity
KM417_RS25380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM417_RS25385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM417_RS25400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_RS25455	COG0557	exoribonuclease II activity
KM417_RS25460	COG1647	Serine aminopeptidase, S33
KM417_RS25465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM417_RS25470	COG1346	cytolysis
KM417_RS25565	COG4695	Portal protein
KM417_RS25590	COG4974	Belongs to the 'phage' integrase family
KM417_RS25600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM417_RS25605	COG0149	triose-phosphate isomerase activity
KM417_RS25615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM417_RS25630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM417_RS25655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_RS25670	COG2323	membrane
KM417_RS25675	COG0740	serine-type endopeptidase activity
KM417_RS25680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_RS25690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM417_RS25700	COG1051	belongs to the nudix hydrolase family
KM417_RS25710	COG0492	ferredoxin-NADP+ reductase activity
KM417_RS25715	COG0457	Tetratricopeptide repeat
KM417_RS25720	COG0110	maltose O-acetyltransferase activity
KM417_RS25740	COG1950	PFAM Membrane protein of
KM417_RS25750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_RS25755	COG0556	nucleotide-excision repair
KM417_RS25775	COG0789	Transcriptional regulator
KM417_RS25800	COG2855	membrane
KM417_RS25805	COG0583	DNA-binding transcription factor activity
KM417_RS25815	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM417_RS25820	COG0488	(ABC) transporter
KM417_RS25830	COG1132	(ABC) transporter
KM417_RS25835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_RS25840	COG0793	Belongs to the peptidase S41A family
KM417_RS25840	COG3409	Peptidoglycan-binding domain 1 protein
KM417_RS25845	COG2177	Part of the ABC transporter FtsEX involved in
KM417_RS25850	COG2884	Cell division ATP-binding protein ftsE
KM417_RS25865	COG0653	protein targeting
KM417_RS25870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM417_RS25875	COG1278	Cold shock
KM417_RS25880	COG1040	competence protein
KM417_RS25885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM417_RS25890	COG0791	NLP P60 protein
KM417_RS25890	COG1388	LysM domain
KM417_RS25895	COG1733	regulation of RNA biosynthetic process
KM417_RS25900	COG1307	EDD domain protein, DegV family
KM417_RS25905	COG1739	Uncharacterized protein family UPF0029
KM417_RS25910	COG1316	TRANSCRIPTIONal
KM417_RS25915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM417_RS25920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM417_RS25925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM417_RS25935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM417_RS25935	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM417_RS25950	COG3394	polysaccharide catabolic process
KM417_RS25955	COG1486	melibiose metabolic process
KM417_RS25960	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_RS25965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_RS25975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM417_RS25980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM417_RS25985	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_RS25995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_RS26000	COG1301	dicarboxylic acid transport
KM417_RS26010	COG0346	lactoylglutathione lyase activity
KM417_RS26015	COG1511	domain protein
KM417_RS26020	COG0583	DNA-binding transcription factor activity
KM417_RS26025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM417_RS26040	COG1271	oxidase subunit
KM417_RS26045	COG1294	oxidase, subunit
KM417_RS26050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_RS26070	COG2389	metal-binding protein
KM417_RS26080	COG1368	sulfuric ester hydrolase activity
KM417_RS26095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_RS26105	COG1215	transferase activity, transferring glycosyl groups
KM417_RS26110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_RS26115	COG3584	3D domain protein
KM417_RS26115	COG1388	LysM domain
KM417_RS26140	COG4715	Zinc finger, swim domain protein
KM417_RS26145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_RS26185	COG0577	efflux transmembrane transporter activity
KM417_RS26190	COG1136	(ABC) transporter
KM417_RS26225	COG5002	protein histidine kinase activity
KM417_RS26230	COG0745	RESPONSE REGULATOR receiver
KM417_RS26235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM417_RS26255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM417_RS26260	COG1134	teichoic acid transport
KM417_RS26265	COG1682	transport, permease protein
KM417_RS26270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM417_RS26315	COG1609	Transcriptional regulator
KM417_RS26330	COG0739	heme binding
KM417_RS26350	COG2385	sporulation resulting in formation of a cellular spore
KM417_RS26365	COG4836	Membrane
KM417_RS26370	COG1007	ATP synthesis coupled electron transport
KM417_RS26375	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM417_RS26380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM417_RS26390	COG0839	Belongs to the complex I subunit 6 family
KM417_RS26405	COG0649	NAD binding
KM417_RS26410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM417_RS26425	COG5001	Diguanylate cyclase
KM417_RS26425	COG3300	MHYT domain
KM417_RS26475	COG0356	it plays a direct role in the translocation of protons across the membrane
KM417_RS26510	COG0698	ribose 5-phosphate isomerase
KM417_RS26520	COG2190	(PTS) system
KM417_RS26525	COG2259	Doxx family
KM417_RS26530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM417_RS26545	COG0009	L-threonylcarbamoyladenylate synthase
KM417_RS26560	COG2890	protein-(glutamine-N5) methyltransferase activity
KM417_RS26580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM417_RS26585	COG1494	fructose-1,6-bisphosphatase
KM417_RS26605	COG4821	SIS domain
KM417_RS26615	COG3343	RNA polymerase activity
KM417_RS26625	COG1960	acyl-CoA dehydrogenase activity
KM417_RS26630	COG1960	acyl-CoA dehydrogenase activity
KM417_RS26635	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM417_RS26640	COG0183	Belongs to the thiolase family
KM417_RS26645	COG0247	lactate metabolic process
KM417_RS26645	COG2181	nitrate reductase activity
KM417_RS26650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_RS26660	COG3300	MHYT domain
KM417_RS26660	COG5001	Diguanylate cyclase
KM417_RS26680	COG2197	response regulator
KM417_RS26685	COG4585	Histidine kinase
KM417_RS26690	COG0842	Transport permease protein
KM417_RS26695	COG1131	(ABC) transporter
KM417_RS26700	COG0024	Methionine aminopeptidase
KM417_RS26710	COG2234	aminopeptidase activity
KM417_RS26730	COG1595	DNA-templated transcription, initiation
KM417_RS26735	COG0018	arginyl-trna synthetase
KM417_RS26740	COG4506	Protein conserved in bacteria
KM417_RS26745	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_RS26760	COG0010	Belongs to the arginase family
KM417_RS26770	COG2814	Major facilitator Superfamily
KM417_RS26775	COG0789	Transcriptional regulator
KM417_RS26780	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_RS26785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_RS26795	COG1994	Peptidase M50
KM417_RS26805	COG1078	dGTPase activity
KM417_RS26810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_RS26815	COG1120	ATPase activity
KM417_RS26820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_RS26845	COG0095	Lipoate-protein ligase
KM417_RS26850	COG0280	phosphate acetyltransferase
KM417_RS26865	COG3773	Cell wall hydrolase
KM417_RS26875	COG2363	Small membrane protein
KM417_RS26885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM417_RS26890	COG2233	PERMEase
KM417_RS26895	COG0561	phosphatase activity
KM417_RS26900	COG2814	Major facilitator Superfamily
KM417_RS26910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_RS26915	COG1131	(ABC) transporter
KM417_RS26920	COG2755	lipolytic protein G-D-S-L family
KM417_RS26925	COG1609	Transcriptional regulator
KM417_RS26935	COG0460	homoserine dehydrogenase
KM417_RS26945	COG2873	o-acetylhomoserine
KM417_RS26955	COG1011	Hydrolase
KM417_RS26960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM417_RS26970	COG2197	response regulator
KM417_RS26980	COG0351	phosphomethylpyrimidine kinase
KM417_RS26985	COG3706	GGDEF domain
KM417_RS26990	COG2879	small protein
KM417_RS26995	COG1966	Carbon starvation protein
KM417_RS27000	COG3279	Response regulator of the LytR AlgR family
KM417_RS27005	COG0477	Major facilitator Superfamily
KM417_RS27030	COG0840	transmembrane signaling receptor activity
KM417_RS27040	COG1607	acyl-coa hydrolase
KM417_RS27055	COG0488	(ABC) transporter
KM417_RS27075	COG0463	Glycosyl transferase, family 2
KM417_RS27080	COG1309	transcriptional regulator
KM417_RS27085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM417_RS27090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_RS27090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_RS27095	COG0628	permease
KM417_RS27110	COG3279	Response regulator of the LytR AlgR family
KM417_RS27115	COG3275	phosphorelay sensor kinase activity
KM417_RS27120	COG2814	Major facilitator Superfamily
KM417_RS27125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_RS27130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM417_RS27135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_RS27155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM417_RS27160	COG1272	protein, Hemolysin III
KM417_RS27180	COG0516	GMP reductase activity
KM417_RS27185	COG1164	Oligoendopeptidase f
KM417_RS27205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_RS27210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM417_RS27215	COG4853	Protein conserved in bacteria
KM417_RS27220	COG4863	YycH protein
KM417_RS27225	COG5002	protein histidine kinase activity
KM417_RS27230	COG0745	RESPONSE REGULATOR receiver
KM417_RS27260	COG0305	Participates in initiation and elongation during chromosome replication
KM417_RS27270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM417_RS27275	COG4241	membrane
KM417_RS27285	COG0629	single-stranded DNA binding
KM417_RS27295	COG0012	GTP binding
KM417_RS27300	COG4481	Protein conserved in bacteria
KM417_RS27305	COG0668	transmembrane transport
KM417_RS27315	COG1475	DNA binding
KM417_RS27320	COG1192	Involved in chromosome partitioning
KM417_RS27345	COG1847	R3H domain protein
KM417_RS27350	COG0706	membrane insertase activity
KM417_RS27360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM417_RS27415	COG3344	reverse transcriptase
KM417_RS27495	COG3344	reverse transcriptase
KM417_RS27700	COG4962	Type ii secretion system protein e
KM417_RS27835	COG2311	Membrane
KM417_RS27855	COG4196	transglutaminase domain protein
KM417_RS27860	COG0671	phosphoesterase, PA-phosphatase related
KM417_RS27880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM417_RS27885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM417_RS28055	COG2002	toxin-antitoxin pair type II binding
KM417_RS28065	COG4974	Belongs to the 'phage' integrase family
KM417_RS28125	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM417_RS28135	COG4974	Belongs to the 'phage' integrase family
KM417_RS28160	COG0457	Tetratricopeptide repeat
KM417_RS28365	COG0791	NLP P60 protein
KM417_RS28365	COG0741	lytic transglycosylase activity
KM417_RS28485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_RS28495	COG4166	transmembrane transport
KM417_RS28540	COG1280	lysine exporter protein (LysE YggA)
KM417_RS28575	COG0681	Belongs to the peptidase S26 family
KM417_RS28650	COG1309	transcriptional regulator
KM417_RS28655	COG1683	Conserved Protein
KM417_RS28700	COG1192	Involved in chromosome partitioning